Transmembrane protein 86A

Overview
NameTransmembrane protein 86A
Smed IDSMED30014236
Length (bp)907
Neoblast Clusters

Zeng et. al., 2018



▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)



Explore this single cell expression dataset with our NB Cluster Shiny App



 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of Transmembrane protein 86A (SMED30014236) t-SNE clustered cells

Violin plots show distribution of expression levels for Transmembrane protein 86A (SMED30014236) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of Transmembrane protein 86A (SMED30014236) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for Transmembrane protein 86A (SMED30014236) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
Sort Descending | Sort Ascending | Only Non-Zero Values | Tile/Chart | Reset

Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020



SMED30014236

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 5

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
protonephridiaSMED30014236SMESG000038930.1 dd_Smed_v4_5848_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
parenchymal cellSMED30014236SMESG000038930.1 dd_Smed_v4_5848_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
Smed sexual biotypeSMED30014236SMESG000038930.1 Contig46874newmark_estsPMID:29674431
Fincher et al., 2018		FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
Smed sexual biotypeSMED30014236SMESG000038930.1 Contig46874uc_Smed_v2PMID:29674431
Fincher et al., 2018		FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
epidermisSMED30014236SMESG000038930.1 dd_Smed_v4_5848_0_1dd_Smed_v4PMID:28292427
Wurtzel et al., 2017		whole organism asexual adult single-cell RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
[Close]
BLAST of Transmembrane protein 86A vs. Ensembl Human
Match: TMEM86A (transmembrane protein 86A [Source:HGNC Symbol;Acc:HGNC:26890])

HSP 1 Score: 118.242 bits (295), Expect = 3.388e-31
Identity = 75/227 (33.04%), Postives = 129/227 (56.83%), Query Frame = 2 
Query:   86 LLKSVIPLLIPFFKTSALYFILSNHLSESKILFSILKCTPIITLLIFVISRC--YISRCFSSYRILVSAGLILSCIGDVFLVYKPEGYLIHGIVAFGIAQVIYTCAFGFRQF---KGKIAGALFACGVCIYRLIYPNLTGILVIACPIYMSMLGCMIWRATSRAEWSNRELCTSKLLPAIGSILFMISDIILALSLF-HVITFTGCGNAIMFTYYAAQMFIALSCTD 748
            ++KS  P L+PFFK + +YF+L    S    + +++KC PI  L +F+++    ++    S+ RI V  GL+ S +GD FL+++ +GY +HG++ F +  + Y  AFG +      G +  AL   G+C Y L+YP L+G       +Y++++G M WRA +    +  +   ++L    G++ F+ISD+ +AL+ F   + ++     IM TYY AQM +ALS  +
Sbjct:    7 VVKSEGPKLVPFFKATCVYFVLWLPSSSPSWVSTLIKCLPIFCLWLFLLAHGLGFLLAHPSATRIFV--GLVFSAVGDAFLIWQDQGYFVHGLLMFAVTHMFYASAFGMQPLALRTGLVMAAL--SGLC-YALLYPCLSGAFTYLVGVYVALIGFMGWRAMAGLRLAGADWRWTELAAGSGALFFIISDLTIALNKFCFPVPYSRA--LIMSTYYVAQMLVALSAVE 226
[Close]
BLAST of Transmembrane protein 86A vs. Ensembl Human
Match: TMEM86B (transmembrane protein 86B [Source:HGNC Symbol;Acc:HGNC:28448])

HSP 1 Score: 61.6178 bits (148), Expect = 1.430e-10
Identity = 60/214 (28.04%), Postives = 98/214 (45.79%), Query Frame = 2 
Query:  110 LIPFFKTSALYFILSNHLSESKILFSILKCTPIITLLIFVISRCYISRCFSSYRILVSAGLILSCIGDVFLVYKPEGYLIHGIVAFGIAQVIYTCAFGFRQFK-GKIAGALFACGVCIYRLIYPNLTGILVIACPIYMSMLGCMIWRATSR---AEWSNRELCTSKLLPAIGSILFMISDIILALSLFHVITFTGCGNAIMFTYYAAQMFIALS 739
            L PF  +  +YF L     +     +++KC P++ L  F+    ++      Y  L+   L+ S +GD  L++ P  + + G+ AF  A ++Y  AFGF   + G +   + A G  +  L+  +L   +V+    Y  +L  M+WR  ++   A W              G++LF +SD +LA   F           IM TYYAAQ+ I LS
Sbjct:   25 LSPFILSCCVYFCLWIPEDQLSWFAALVKCLPVLCLAGFL----WVMSPSGGYTQLLQGALVCSAVGDACLIW-PAAF-VPGMAAFATAHLLYVWAFGFSPLQPGLLLLIILAPGPYL-SLVLQHLEPDMVLPVAAYGLILMAMLWRGLAQGGSAGW--------------GALLFTLSDGVLAWDTF-AQPLPHAHLVIMTTYYAAQLLITLS 216
[Close]
BLAST of Transmembrane protein 86A vs. Ensembl Fly
Match: CG7582 (gene:FBgn0039681 transcript:FBtr0085464)

HSP 1 Score: 99.7525 bits (247), Expect = 1.694e-24
Identity = 76/238 (31.93%), Postives = 117/238 (49.16%), Query Frame = 2 
Query:   92 KSVIPLLIPFFKTSALYFILSNHLSESKILFSILKCTPIITLLIFVISRCYISRCFSSYRILVSAGLILSCIGDVFLVYKPEGYLIHGIVAFGIAQVIYTCAFGFRQFKGKIAGALF-ACGVCIYR------------------LIYPNLTGILVIACPIYMSMLGCMIWRATSRAEWSNRELCTSKLLPAIGSILFMISDIILALSLFHVITFTGCGNAIMFTYYAAQMFIALSCTD 748
            KS  P L+PF  T  LYF L     + ++  ++LKC PI  L+ +V+++    +      + +  GL+ S  GD  L          G+++FG+A V Y  AFG++  K  I   L+ A  +C +                    ++  L  IL+I  PIY  ++  M+WR+ +RA  S   L    +  AIG+ILF+ISD ++A+++F  +        IM TYYAAQ  IALS  D
Sbjct:    9 KSQGPKLVPFLVTIVLYFSLVRKDPQGELWTTVLKCLPIFALVFYVVAKGISLKKEYRRSLWILLGLVFSSGGDALLNIN---LFPFGMISFGVAHVFYISAFGWKPIKWFIGLLLYVAVSLCKFTGHYIRIPYLEYLKPPVVYFVHTKLDEILIIGVPIYCFLITTMLWRSLARAVDSRNFLA---VFCAIGAILFVISDALIAVTMFVGVPLPCARLQIMITYYAAQFAIALSTAD 240
[Close]
BLAST of Transmembrane protein 86A vs. Ensembl Fly
Match: CG7582 (gene:FBgn0039681 transcript:FBtr0308238)

HSP 1 Score: 77.411 bits (189), Expect = 3.379e-17
Identity = 49/131 (37.40%), Postives = 73/131 (55.73%), Query Frame = 2 
Query:  356 IVAFGIAQVIYTCAFGFRQFKGKIAGALFACGVCIYRLIYPNLTGILVIACPIYMSMLGCMIWRATSRAEWSNRELCTSKLLPAIGSILFMISDIILALSLFHVITFTGCGNAIMFTYYAAQMFIALSCTD 748
            +++FG+A V Y  AFG++  K  I   L+         ++  L  IL+I  PIY  ++  M+WR+ +RA  S   L    +  AIG+ILF+ISD ++A+++F  +        IM TYYAAQ  IALS  D
Sbjct:    1 MISFGVAHVFYISAFGWKPIKWFIGLLLYVAVSLFVYFVHTKLDEILIIGVPIYCFLITTMLWRSLARAVDSRNFLA---VFCAIGAILFVISDALIAVTMFVGVPLPCARLQIMITYYAAQFAIALSTAD 128
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BLAST of Transmembrane protein 86A vs. Ensembl Zebrafish
Match: CT573392.2 (pep chromosome:GRCz11:CHR_ALT_CTG25_1_21:24252904:24261865:1 gene:ENSDARG00000112825.1 transcript:ENSDART00000180373.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CT573392.2)

HSP 1 Score: 132.109 bits (331), Expect = 9.432e-37
Identity = 77/223 (34.53%), Postives = 127/223 (56.95%), Query Frame = 2 
Query:   86 LLKSVIPLLIPFFKTSALYFILSNHLSESKILFSILKCTPIITLLIFVISR--CYISRCFSSYRILVSAGLILSCIGDVFLVYKPEGYLIHGIVAFGIAQVIYTCAFGFRQFKGKIAGALFACGVCIYRLIYPNLTGILVIACPIYMSMLGCMIWRATSRAEWSNRELCTSKLLPAIGSILFMISDIILALSLFHVITFTGCGNAIMFTYYAAQMFIALSCTD 748
            L+KS  P L+PFFK + +YF+L    S      +++KC PI  L +F+++    ++    S+ +IL  AGLI S +GD FL+++ +GY  HG++ F I  ++Y+ AFG +    +    +       Y L+YP L+G       +Y++++G M WRA +  +++N     +KL   +G++LFM+SD+ +A++ F           IM TYYAAQM IALS  +
Sbjct:    8 LVKSEGPKLVPFFKATCVYFVLWLPTSSPSWFSALIKCLPIFCLWVFLLAHGINFLGAHSSARKIL--AGLIFSALGDAFLIWQEQGYFSHGLLMFAITHILYSSAFGMKPLNSRAGLIIAVISGFSYTLLYPYLSGPFTYLVAVYIALIGFMGWRAIAGVQFANDLWTWTKLSACLGAVLFMVSDLTIAVNKF-CFPVPHSRAIIMATYYAAQMLIALSAVE 227
[Close]
BLAST of Transmembrane protein 86A vs. Ensembl Zebrafish
Match: tmem86a (transmembrane protein 86A [Source:ZFIN;Acc:ZDB-GENE-050320-81])

HSP 1 Score: 130.954 bits (328), Expect = 2.830e-36
Identity = 76/223 (34.08%), Postives = 127/223 (56.95%), Query Frame = 2 
Query:   86 LLKSVIPLLIPFFKTSALYFILSNHLSESKILFSILKCTPIITLLIFVISR--CYISRCFSSYRILVSAGLILSCIGDVFLVYKPEGYLIHGIVAFGIAQVIYTCAFGFRQFKGKIAGALFACGVCIYRLIYPNLTGILVIACPIYMSMLGCMIWRATSRAEWSNRELCTSKLLPAIGSILFMISDIILALSLFHVITFTGCGNAIMFTYYAAQMFIALSCTD 748
            ++KS  P L+PFFK + +YF+L    S      +++KC PI  L +F+++    ++    S+ +IL  AGLI S +GD FL+++ +GY  HG++ F I  ++Y+ AFG +    +    +       Y L+YP L+G       +Y++++G M WRA +  +++N     +KL   +G++LFM+SD+ +A++ F           IM TYYAAQM IALS  +
Sbjct:    7 VVKSEGPKLVPFFKATCVYFVLWLPTSSPSWFSALIKCLPIFCLWVFLLAHGINFLGAHSSARKIL--AGLIFSALGDAFLIWQEQGYFSHGLLMFAITHILYSSAFGMKPLNSRAGLIIAVISGFSYTLLYPYLSGPFTYLVAVYIALIGFMGWRAIAGVQFANDLWTWTKLSACLGAVLFMVSDLTIAVNKF-CFPVPHSRAIIMATYYAAQMLIALSAVE 226
[Close]
BLAST of Transmembrane protein 86A vs. Ensembl Zebrafish
Match: tmem86b (transmembrane protein 86B [Source:ZFIN;Acc:ZDB-GENE-060825-132])

HSP 1 Score: 53.1434 bits (126), Expect = 8.417e-8
Identity = 63/221 (28.51%), Postives = 108/221 (48.87%), Query Frame = 2 
Query:  110 LIPFFKTSALYFILSNHLSESKILFSILKCTPIITLLIFVISRCYISRCFSSYRIL-VSAGLILSCIGDVFLVYKPEGYLIHGIVAFGIAQVIYTCAFGFRQFKGKIAGA----------LFACGVCIYRLIYPNLTGILVIACPIYMSMLGCMIWRATSRAEWSNRELCTSKLLPAIGSILFMISDIILALSLFHVITFTGCGNAIMFTYYAAQMFIALS 739
            L+PF  +  LYF L    S   +L + +K  PI++L++ V+S          + ++ V+ GL+LS  GD  L++ PE + IHG+  F +A ++Y+  F   ++    +            LF  G+ +Y + +  L     +  P     +  ++  AT  A        T + L  +GS++FM SD+ +AL+ F+V+      + IM TYY AQ+ IAL 
Sbjct:   25 LLPFIASCTLYFYLWIPDSAPSLLAAGIKAAPILSLVLLVLSYN------GGWSLVGVAGGLLLSAGGDCCLIW-PELF-IHGMGCFALAHLLYSVTFLSSRYSSTSSSFSFFFLYLVLWLFGVGIYVYLMPFLQLDPEADVLVPAIGGYVLLIVIMATMAAR-------TRRPLILLGSLVFMASDLTIALTKFNVVDTEYKRHIIMVTYYLAQLMIALG 230
[Close]
BLAST of Transmembrane protein 86A vs. Ensembl Xenopus
Match: tmem86a (transmembrane protein 86A [Source:NCBI gene;Acc:100145092])

HSP 1 Score: 114.39 bits (285), Expect = 1.256e-29
Identity = 71/216 (32.87%), Postives = 114/216 (52.78%), Query Frame = 2 
Query:   92 KSVIPLLIPFFKTSALYFILSNHLSESKILFSILKCTPIITLLIFVISRCYISRCFSSYRILVSAGLILSCIGDVFLVYKPEGYLIHGIVAFGIAQVIYTCAFGFRQFKGKIAGALFACGVCIYRLIYPNLTGILVIACPIYMSMLGCMIWRATSRAEWSNRELCTSKLLPAIGSILFMISDIILALSLFHVITFTGCGNAIMFTYYAAQMFIALS 739
            +SVIP L+PF  +   YF L   LSE  +  +++K  P++ L  F++        FSSY   +  GL+ S  GD+ L++  E + +HG+V FG+A ++Y  +FGFR  + ++   L       +    P L G  +   P Y  ++G M WRA +R   ++ +   + +  A+GS++F++SD  LA+  F           +M TYY  QMFIALS
Sbjct:   26 RSVIPKLLPFLISCYNYFALWLPLSEPNLFHALIKSLPVLCLGFFIVVHSLSQGRFSSYSKKIFVGLMFSAAGDICLLW--EDFFLHGMVMFGLAHIMYIISFGFRPLRLRLFILLALFCAAFFFFALPYLHGPFLYMVPGYSVLIGTMAWRALARVSLASYKFSWAHVFAALGSLIFVVSDCFLAVDKF-CFPIENSRAIVMATYYGGQMFIALS 238
[Close]
BLAST of Transmembrane protein 86A vs. Ensembl Xenopus
Match: tmem86a (transmembrane protein 86A [Source:NCBI gene;Acc:100145092])

HSP 1 Score: 114.005 bits (284), Expect = 1.332e-29
Identity = 71/216 (32.87%), Postives = 114/216 (52.78%), Query Frame = 2 
Query:   92 KSVIPLLIPFFKTSALYFILSNHLSESKILFSILKCTPIITLLIFVISRCYISRCFSSYRILVSAGLILSCIGDVFLVYKPEGYLIHGIVAFGIAQVIYTCAFGFRQFKGKIAGALFACGVCIYRLIYPNLTGILVIACPIYMSMLGCMIWRATSRAEWSNRELCTSKLLPAIGSILFMISDIILALSLFHVITFTGCGNAIMFTYYAAQMFIALS 739
            +SVIP L+PF  +   YF L   LSE  +  +++K  P++ L  F++        FSSY   +  GL+ S  GD+ L++  E + +HG+V FG+A ++Y  +FGFR  + ++   L       +    P L G  +   P Y  ++G M WRA +R   ++ +   + +  A+GS++F++SD  LA+  F           +M TYY  QMFIALS
Sbjct:   19 RSVIPKLLPFLISCYNYFALWLPLSEPNLFHALIKSLPVLCLGFFIVVHSLSQGRFSSYSKKIFVGLMFSAAGDICLLW--EDFFLHGMVMFGLAHIMYIISFGFRPLRLRLFILLALFCAAFFFFALPYLHGPFLYMVPGYSVLIGTMAWRALARVSLASYKFSWAHVFAALGSLIFVVSDCFLAVDKF-CFPIENSRAIVMATYYGGQMFIALS 231
[Close]
BLAST of Transmembrane protein 86A vs. Ensembl Xenopus
Match: tmem86a (transmembrane protein 86A [Source:NCBI gene;Acc:100145092])

HSP 1 Score: 112.464 bits (280), Expect = 4.530e-29
Identity = 71/215 (33.02%), Postives = 113/215 (52.56%), Query Frame = 2 
Query:   95 SVIPLLIPFFKTSALYFILSNHLSESKILFSILKCTPIITLLIFVISRCYISRCFSSYRILVSAGLILSCIGDVFLVYKPEGYLIHGIVAFGIAQVIYTCAFGFRQFKGKIAGALFACGVCIYRLIYPNLTGILVIACPIYMSMLGCMIWRATSRAEWSNRELCTSKLLPAIGSILFMISDIILALSLFHVITFTGCGNAIMFTYYAAQMFIALS 739
            SVIP L+PF  +   YF L   LSE  +  +++K  P++ L  F++        FSSY   +  GL+ S  GD+ L++  E + +HG+V FG+A ++Y  +FGFR  + ++   L       +    P L G  +   P Y  ++G M WRA +R   ++ +   + +  A+GS++F++SD  LA+  F           +M TYY  QMFIALS
Sbjct:   15 SVIPKLLPFLISCYNYFALWLPLSEPNLFHALIKSLPVLCLGFFIVVHSLSQGRFSSYSKKIFVGLMFSAAGDICLLW--EDFFLHGMVMFGLAHIMYIISFGFRPLRLRLFILLALFCAAFFFFALPYLHGPFLYMVPGYSVLIGTMAWRALARVSLASYKFSWAHVFAALGSLIFVVSDCFLAVDKF-CFPIENSRAIVMATYYGGQMFIALS 226
[Close]
BLAST of Transmembrane protein 86A vs. Ensembl Mouse
Match: Tmem86a (transmembrane protein 86A [Source:MGI Symbol;Acc:MGI:1915143])

HSP 1 Score: 119.013 bits (297), Expect = 1.255e-31
Identity = 78/230 (33.91%), Postives = 124/230 (53.91%), Query Frame = 2 
Query:   86 LLKSVIPLLIPFFKTSALYFILSNHLSESKILFSILKCTPIITLLIFVISRCYISRCFSSYRILVSAGLILSCIGDVFLVYKPEGYLIHGIVAFGIAQVIYTCAFGFRQFK---GKIAGALFACGVCIYRLIYPNLTGILVIACPIYMSMLGCMIWRATS-----RAEWSNRELCTSKLLPAIGSILFMISDIILALSLF-HVITFTGCGNAIMFTYYAAQMFIALSCTD 748
            ++KS  P L+PFFK + +YF+L    S    + +++KC PI  L +F+++             L+  GL+ S +GD FL+++  GY  HG++ F +A ++Y  AFG R      G + G L   G+C Y L+YP L+G       +Y++++  M WRA +      A W   EL         G++LF++SD+ +AL+ F   + ++     IM TYYAAQM IALS  +
Sbjct:    7 VVKSEGPKLVPFFKATCVYFVLWLPSSSPSWVSALIKCLPIFCLWLFLLAHGVRFLLAHPSASLIFVGLVFSAVGDAFLIWQDHGYFEHGLLMFAVAHILYAAAFGMRPLALRTGLVIGVL--SGLC-YALLYPGLSGAFTYLVGVYVALISFMGWRAMAGLRLVGAAWRWTELAAGG-----GALLFILSDLTIALNKFCFPVPYSRA--LIMSTYYAAQMLIALSAVE 226
[Close]
BLAST of Transmembrane protein 86A vs. Ensembl Mouse
Match: Tmem86b (transmembrane protein 86B [Source:MGI Symbol;Acc:MGI:1915505])

HSP 1 Score: 64.3142 bits (155), Expect = 1.100e-11
Identity = 60/213 (28.17%), Postives = 100/213 (46.95%), Query Frame = 2 
Query:  110 LIPFFKTSALYFILSNHLSESKILFSILKCTPIITLLIFVISRCYISRCFSSYRILVSAGLILSCIGDVFLVYKPEGYLIHGIVAFGIAQVIYTCAFGFRQFKGKIAGALFACGVCIYRLIYPNLTGILVIACPIYMSMLGCMIWRA---TSRAEWSNRELCTSKLLPAIGSILFMISDIILALSLFHVITFTGCGNAIMFTYYAAQMFIALS 739
            L PF    +LYF+L   + +   + +++KC PI+ L++F+ +   ++   SS  +L  A L+ S +GD  L++ PE +  +G  AF +A + Y  AFG    +  +        +  Y  +  +L   +V+    Y  +L  M+WR+      A W              G++LF  SD +LA   F V +        M TYYAAQ+ + LS
Sbjct:   25 LAPFILACSLYFLLWIPVDQPSWVSALIKCQPILCLVVFLWA---VAPGGSSTWLLQGA-LVCSAVGDACLIW-PEAF-FYGTAAFSVAHLFYLGAFGLTPLQPGLLLCTTLASLTYYSFLLLHLEQGMVLPVMAYGLILNSMLWRSLVWGGSASW--------------GAVLFTFSDGVLAWDTF-VYSLPFARLVTMSTYYAAQLLLILS 216
[Close]
BLAST of Transmembrane protein 86A vs. Ensembl Mouse
Match: Tmem86b (transmembrane protein 86B [Source:MGI Symbol;Acc:MGI:1915505])

HSP 1 Score: 64.3142 bits (155), Expect = 1.144e-11
Identity = 60/213 (28.17%), Postives = 100/213 (46.95%), Query Frame = 2 
Query:  110 LIPFFKTSALYFILSNHLSESKILFSILKCTPIITLLIFVISRCYISRCFSSYRILVSAGLILSCIGDVFLVYKPEGYLIHGIVAFGIAQVIYTCAFGFRQFKGKIAGALFACGVCIYRLIYPNLTGILVIACPIYMSMLGCMIWRA---TSRAEWSNRELCTSKLLPAIGSILFMISDIILALSLFHVITFTGCGNAIMFTYYAAQMFIALS 739
            L PF    +LYF+L   + +   + +++KC PI+ L++F+ +   ++   SS  +L  A L+ S +GD  L++ PE +  +G  AF +A + Y  AFG    +  +        +  Y  +  +L   +V+    Y  +L  M+WR+      A W              G++LF  SD +LA   F V +        M TYYAAQ+ + LS
Sbjct:   20 LAPFILACSLYFLLWIPVDQPSWVSALIKCQPILCLVVFLWA---VAPGGSSTWLLQGA-LVCSAVGDACLIW-PEAF-FYGTAAFSVAHLFYLGAFGLTPLQPGLLLCTTLASLTYYSFLLLHLEQGMVLPVMAYGLILNSMLWRSLVWGGSASW--------------GAVLFTFSDGVLAWDTF-VYSLPFARLVTMSTYYAAQLLLILS 211
[Close]
BLAST of Transmembrane protein 86A vs. UniProt/SwissProt
Match: sp|Q3MHQ7|TM86A_BOVIN (Lysoplasmalogenase-like protein TMEM86A OS=Bos taurus OX=9913 GN=TMEM86A PE=2 SV=1)

HSP 1 Score: 126.331 bits (316), Expect = 1.291e-33
Identity = 80/226 (35.40%), Postives = 129/226 (57.08%), Query Frame = 2 
Query:   86 LLKSVIPLLIPFFKTSALYFILSNHLSESKILFSILKCTPIITLLIFVISRC--YISRCFSSYRILVSAGLILSCIGDVFLVYKPEGYLIHGIVAFGIAQVIYTCAFGFRQFKGKIAGALFA--CGVCIYRLIYPNLTGILVIACPIYMSMLGCMIWRATSRAEWSNRELCTSKLLPAIGSILFMISDIILALSLF-HVITFTGCGNAIMFTYYAAQMFIALSCTD 748
            ++KS  P L+PFFK + +YF+L    S    + +++KC PI  L +F+++    ++    S+ RI V  GL+ S IGD FL+++ +GY +HG++ F +  ++Y  AFG R   G   G L     G+C Y  +YPNLTG       +Y++++G M WRA +  +        ++L    G++LF++SD+ +AL  F   + ++     IM TYYAAQM IALS  +
Sbjct:    7 VVKSEGPKLVPFFKATCVYFVLWLPSSSPSWVSALIKCLPIFCLWLFLLAHGLGFLLTHPSATRIFV--GLVFSAIGDAFLIWQDQGYFVHGMLMFAVTHMLYASAFGMRPL-GLRTGLLMVILSGLC-YAFLYPNLTGAFTYVVGVYVAIIGFMGWRAMAGLQLVGAAWRWTELAAGTGALLFIVSDLTIALDKFCFPVPYSRA--LIMSTYYAAQMLIALSAVE 226
[Close]
BLAST of Transmembrane protein 86A vs. UniProt/SwissProt
Match: sp|Q9D8N3|TM86A_MOUSE (Lysoplasmalogenase-like protein TMEM86A OS=Mus musculus OX=10090 GN=Tmem86a PE=2 SV=1)

HSP 1 Score: 119.013 bits (297), Expect = 8.776e-31
Identity = 78/230 (33.91%), Postives = 124/230 (53.91%), Query Frame = 2 
Query:   86 LLKSVIPLLIPFFKTSALYFILSNHLSESKILFSILKCTPIITLLIFVISRCYISRCFSSYRILVSAGLILSCIGDVFLVYKPEGYLIHGIVAFGIAQVIYTCAFGFRQFK---GKIAGALFACGVCIYRLIYPNLTGILVIACPIYMSMLGCMIWRATS-----RAEWSNRELCTSKLLPAIGSILFMISDIILALSLF-HVITFTGCGNAIMFTYYAAQMFIALSCTD 748
            ++KS  P L+PFFK + +YF+L    S    + +++KC PI  L +F+++             L+  GL+ S +GD FL+++  GY  HG++ F +A ++Y  AFG R      G + G L   G+C Y L+YP L+G       +Y++++  M WRA +      A W   EL         G++LF++SD+ +AL+ F   + ++     IM TYYAAQM IALS  +
Sbjct:    7 VVKSEGPKLVPFFKATCVYFVLWLPSSSPSWVSALIKCLPIFCLWLFLLAHGVRFLLAHPSASLIFVGLVFSAVGDAFLIWQDHGYFEHGLLMFAVAHILYAAAFGMRPLALRTGLVIGVL--SGLC-YALLYPGLSGAFTYLVGVYVALISFMGWRAMAGLRLVGAAWRWTELAAGG-----GALLFILSDLTIALNKFCFPVPYSRA--LIMSTYYAAQMLIALSAVE 226
[Close]
BLAST of Transmembrane protein 86A vs. UniProt/SwissProt
Match: sp|Q8N2M4|TM86A_HUMAN (Lysoplasmalogenase-like protein TMEM86A OS=Homo sapiens OX=9606 GN=TMEM86A PE=1 SV=1)

HSP 1 Score: 118.242 bits (295), Expect = 1.627e-30
Identity = 75/227 (33.04%), Postives = 129/227 (56.83%), Query Frame = 2 
Query:   86 LLKSVIPLLIPFFKTSALYFILSNHLSESKILFSILKCTPIITLLIFVISRC--YISRCFSSYRILVSAGLILSCIGDVFLVYKPEGYLIHGIVAFGIAQVIYTCAFGFRQF---KGKIAGALFACGVCIYRLIYPNLTGILVIACPIYMSMLGCMIWRATSRAEWSNRELCTSKLLPAIGSILFMISDIILALSLF-HVITFTGCGNAIMFTYYAAQMFIALSCTD 748
            ++KS  P L+PFFK + +YF+L    S    + +++KC PI  L +F+++    ++    S+ RI V  GL+ S +GD FL+++ +GY +HG++ F +  + Y  AFG +      G +  AL   G+C Y L+YP L+G       +Y++++G M WRA +    +  +   ++L    G++ F+ISD+ +AL+ F   + ++     IM TYY AQM +ALS  +
Sbjct:    7 VVKSEGPKLVPFFKATCVYFVLWLPSSSPSWVSTLIKCLPIFCLWLFLLAHGLGFLLAHPSATRIFV--GLVFSAVGDAFLIWQDQGYFVHGLLMFAVTHMFYASAFGMQPLALRTGLVMAAL--SGLC-YALLYPCLSGAFTYLVGVYVALIGFMGWRAMAGLRLAGADWRWTELAAGSGALFFIISDLTIALNKFCFPVPYSRA--LIMSTYYVAQMLVALSAVE 226
[Close]
BLAST of Transmembrane protein 86A vs. UniProt/SwissProt
Match: sp|F1RMN2|TM86B_PIG (Lysoplasmalogenase OS=Sus scrofa OX=9823 GN=TMEM86B PE=3 SV=1)

HSP 1 Score: 81.2629 bits (199), Expect = 6.374e-17
Identity = 62/213 (29.11%), Postives = 103/213 (48.36%), Query Frame = 2 
Query:  110 LIPFFKTSALYFILSNHLSESKILFSILKCTPIITLLIFVISRCYISRCFSSYRILVSAGLILSCIGDVFLVYKPEGYLIHGIVAFGIAQVIYTCAFGFRQFKGKIAGALFACGVCIYRLIYPNLTGILVIACPIYMSMLGCMIWRATSRAEWSNRELCTSKLLPAIGSILFMISDIILALSLFHVITFTGCGNAIMFTYYAAQMFIALSCTD 748
            L PFF T A+YF+L     +   + +++KC P+++L++F+ +          Y   +   L+ S +GD  LV+ PE +L HG+ AF  A ++Y  AFG    +  +   +    +  Y L+  +L   LV+A   Y   L  M+WR  +R   +             G++LF +SD  LA + F           +M TYY+AQ+ I+LS + 
Sbjct:   25 LSPFFFTCAVYFLLWIPDDQPSWVGALVKCLPVLSLVVFLRA----VDAGGGYSARLQGALLCSAVGDACLVW-PEAFL-HGVAAFAAAHLLYLWAFGLTPLQPGLLLLVILAALPYYGLLLWHLPPDLVLALTAYSLALATMLWRGLARGGSTG-----------WGALLFTLSDTTLAWNAF-AQPLPHARLVVMTTYYSAQVLISLSVSQ 219
[Close]
BLAST of Transmembrane protein 86A vs. UniProt/SwissProt
Match: sp|Q3T0W0|TM86B_BOVIN (Lysoplasmalogenase OS=Bos taurus OX=9913 GN=TMEM86B PE=2 SV=1)

HSP 1 Score: 78.5666 bits (192), Expect = 7.062e-16
Identity = 65/214 (30.37%), Postives = 107/214 (50.00%), Query Frame = 2 
Query:  110 LIPFFKTSALYFILSNHLSESKILFSILKCTPIITLLIFVISRCYISRCFSSYRILVSAGLILSCIGDVFLVYKPEGYLIHGIVAFGIAQVIYTCAFGFRQFKGKIAGALFACGVCIYRLIYPNLTGILVIACPIYMSMLGCMIWRATSR---AEWSNRELCTSKLLPAIGSILFMISDIILALSLFHVITFTGCGNAIMFTYYAAQMFIALSC 742
            L+PFF   A+Y ++ N   +   +  +LK  P++ L  F+ +    +     YR L+   L+ S +GD  LV+ PE  L +G+ AFG+A ++Y  AFG    K  +   L       +R+++P++   +V     Y  +L  M+WR  +R   A W              G++LF++SD +LA ++F  +   G    +M TYY+AQM I LS 
Sbjct:   24 LLPFFLACAVYLLVRN-ADQPPWVNVLLKILPVLYLAGFLGT----AHPGGGYRALLQGALLCSAVGDACLVW-PEA-LRYGMAAFGLAHLLYLRAFGLTPLKPGLLLPLLLVSALYFRVLHPHMPPQVVWPLLAYSIVLVAMLWRGLARGGSAHW--------------GALLFVLSDSVLAWNIFTYLVPHGH-LLVMTTYYSAQMLITLSA 215
[Close]
BLAST of Transmembrane protein 86A vs. TrEMBL
Match: A0A482XSI8 (Uncharacterized protein OS=Laodelphax striatellus OX=195883 GN=LSTR_LSTR003049 PE=4 SV=1)

HSP 1 Score: 147.902 bits (372), Expect = 3.575e-39
Identity = 89/224 (39.73%), Postives = 131/224 (58.48%), Query Frame = 2 
Query:   86 LLKSVIPLLIPFFKTSALYFILSNHLSESKILFSILKCTPIITLLIFVI--SRCYISRCFSSYRILVSAGLILSCIGDVFLVYKPEGYLIHGIVAFGIAQVIYTCAFGFRQFKGKIAGALFACGVCIYRLIYPNLTGILVIACPIYMSMLGCMIWRATSRAEWSNRELCTSKLLPAIGSILFMISDIILALSLF-HVITFTGCGNAIMFTYYAAQMFIALSCTD 748
            +LK V P L+PFFKT A+YF+L   +    +  +++KC PI++L+IFV+            S RIL  +GL+LSC+GD  LV+ PE Y +HG+ AFG+A VIYT AFGF+ F   +   L+     +  ++ P L+G+L I  P+Y  +L   +WRA +R +        +KL    G I+F +SD ++ +  F H I ++     IM TYYAAQ+ IALS  D
Sbjct:    7 VLKVVGPKLVPFFKTVAIYFVLYIPVDRPSLFAAVIKCLPIVSLIIFVLLHGMSLADEYAFSRRIL--SGLVLSCVGDALLVW-PE-YFVHGMAAFGVAHVIYTYAFGFKPFNAALGAILYTLCALVTAVLMPGLSGVLAIGIPVYNCLLVTTVWRAIARVQLFEELWTWTKLCSCAGGIMFAVSDAMIGIHHFYHPILYS--QTLIMVTYYAAQLGIALSVVD 224
[Close]
BLAST of Transmembrane protein 86A vs. TrEMBL
Match: A0A1S3JIA1 (lysoplasmalogenase-like protein TMEM86A OS=Lingula unguis OX=7574 GN=LOC106173154 PE=4 SV=1)

HSP 1 Score: 144.436 bits (363), Expect = 6.540e-38
Identity = 90/227 (39.65%), Postives = 133/227 (58.59%), Query Frame = 2 
Query:   86 LLKSVIPLLIPFFKTSALYFIL-SNHLSESKILFSILKCTPIITLLIFVISRCYISRCFSSYRILVSAGLILSCIGDVFLVYKPEGYLIHGIVAFGIAQVIYTCAFGFRQFKGKIAGALFACGVCIYRLIYPNLTGILVIACPIYMSMLGCMIWRATSRAEWSNRELCTSKLLPAIGSILFMISDIILALSLFHVITFTGCGNAIMFTYYAAQMFIALSCTD-PLSI 760
            +LKSV P L+PFFKT A+YF+L  +  S   I ++I+KC P+I+L++FV+        + +Y   + AGLI SC+GD+FLV+K   +  HG+  F +AQ++Y  AFG R         +   G  +Y ++ P LTGI+ I  P+Y+ ++  M WRA +R +  +     +KL    GSI F+ISD+ +AL  F V+        IM TYYAAQ  IALS  D P+ +
Sbjct:    7 VLKSVGPKLVPFFKTLAIYFVLFGDEASYGSIFYAIIKCLPVISLIVFVLLHGMNLSEYYAYSRRILAGLIFSCLGDIFLVWKHYCFE-HGLAMFAVAQLLYASAFGMRPLNPWAGLVISFLGSIVYTILSPGLTGIMNILVPMYLILILFMAWRAVARVQLFDDLWTWTKLCGCAGSIAFLISDLTIALDKF-VMPIPFGHTIIMTTYYAAQFGIALSVVDSPIDV 231
[Close]
BLAST of Transmembrane protein 86A vs. TrEMBL
Match: R7UKM0 (Uncharacterized protein OS=Capitella teleta OX=283909 GN=CAPTEDRAFT_223328 PE=4 SV=1)

HSP 1 Score: 142.51 bits (358), Expect = 3.135e-37
Identity = 84/226 (37.17%), Postives = 129/226 (57.08%), Query Frame = 2 
Query:   74 KSAPLLKSVIPLLIPFFKTSALYFILSNHLSE-SKILFSILKCTPIITLLIFVISRCYISRCFSSYRILVSAGLILSCIGDVFLVYKPEGYLIHGIVAFGIAQVIYTCAFGFRQFKGKIAGALFACGVCIYRLIYPNLTGILVIACPIYMSMLGCMIWRATSRAEWSNRELCTSKLLPAIGSILFMISDIILALSLFHVITFTGCGNAIMFTYYAAQMFIALSCTD 748
            K + ++K++ P L+PFFKT A++FIL    S  + I + ++KC P++ L+IFV+          +Y   +  GL  SC+GD FLV+K  GY  HG+  F +AQV+YT AFGFR    +        G  +Y LI P L G +V    +Y++++  M WRA +R ++ N     + L  + GS+LF++SD ++A++ F           IM TYYAAQ+ IA+S  D
Sbjct:    9 KPSTVVKAIGPKLVPFFKTVAIFFILFEADSRLNSIFYCLVKCLPVVCLMIFVLMHGMSLSEIYAYSRKILLGLFFSCLGDAFLVWKNAGYFPHGLAMFALAQVMYTWAFGFRPLSLRTCSVCACLGFFVYWLILPGLEGPMVWMAGLYVALICTMAWRAIARVKFLNDGWTWTGLCSSGGSVLFLMSDFVIAVNRFR-FDVPYSHQLIMATYYAAQLGIAVSVVD 233
[Close]
BLAST of Transmembrane protein 86A vs. TrEMBL
Match: A0A433U7W0 (Uncharacterized protein (Fragment) OS=Elysia chlorotica OX=188477 GN=EGW08_002330 PE=4 SV=1)

HSP 1 Score: 144.436 bits (363), Expect = 3.514e-37
Identity = 86/228 (37.72%), Postives = 132/228 (57.89%), Query Frame = 2 
Query:   74 KSAPLLKSVIPLLIPFFKTSALYFILSNHLSESKILFSILKCTPIITLLIFVI-SRCYISRCFS-SYRILVSAGLILSCIGDVFLVYKPEGYLIH-GIVAFGIAQVIYTCAFGFRQFKGKIAGALFACGVCIYRLIYPNLTGILVIACPIYMSMLGCMIWRATSRAEWSNRELCTSKLLPAIGSILFMISDIILALSLFHVITFTGCGNAIMFTYYAAQMFIALSCTD 748
            K   +LKSV P L+PFFKT A++F+L      + + F + KC P+++L+ FV+     +  C+  S RIL   GL+ S +GDVFLV+K        G++ F IAQ +Y  AFG+R  K +      A GV +Y  +   LTG++V   P+YM+++  M WRA +R E  +     +KL   +G++ FM+SD+++A+++F      G    +M TYYAAQ  I+LS  D
Sbjct:   47 KPLTVLKSVGPKLVPFFKTVAIFFVLFGQEERTSVFFCVAKCLPVLSLMAFVLLHGMSLDECYRYSRRIL--TGLVFSLLGDVFLVWKHSFCNFELGLLCFAIAQTMYARAFGWRPLKPRPGLVFLAIGVLVYSYLQLYLTGVMVFLAPLYMTLICTMAWRAVARVEIYDDLWTWTKLCGCVGAVCFMVSDLLIAVNMF-AFPVPGAHQLVMLTYYAAQFGISLSVVD 271
[Close]
BLAST of Transmembrane protein 86A vs. TrEMBL
Match: A0A3M7PMA4 (Lysoplasmalogenase TMEM86A OS=Brachionus plicatilis OX=10195 GN=BpHYR1_022005 PE=4 SV=1)

HSP 1 Score: 142.51 bits (358), Expect = 8.094e-37
Identity = 90/224 (40.18%), Postives = 130/224 (58.04%), Query Frame = 2 
Query:   86 LLKSVIPLLIPFFKTSALYFILSNHLSESKILFSILKCTPIITLLIFVISRCYISRCFSSYRILVSAGLILSCIGDVFLVYKPEGYLIHGIVAFGIAQVIYTCAFGFRQFKGKIAGALFACGVCIYRLIYPNLTG-ILVIACPIYMSMLGCMIWRATSRAEWSNREL--CTSKLLPAIGSILFMISDIILALSLFHVITFTGCGNAIMFTYYAAQMFIALSCTD 748
            ++K V P L+PF ++  ++F+L    SES + F I+KC PII L+IFV+S  +  +   SY   +  GL  S IGD  LVY PE + I G+++FGIA +IY  AFG +    K A AL    + +     P L   +L +  PIYM++L  M+WRA SR +  N+E+    +KL  +IG+  F++SD +L+   F +         IMFTYYAAQ+ IALS  D
Sbjct:    7 VIKHVGPKLVPFLESVFIFFVLYPLKSESNLFFLIIKCMPIIALMIFVLSNGFNLKFEYSYSRRIFTGLFFSMIGDACLVY-PEEFFIFGVISFGIAHIIYLTAFGIKPLNYKFALALSVLALPVTAFYIPFLQNYVLKLIVPIYMALLLSMLWRAVSRLQIFNKEVKWTWTKLCCSIGAFFFVVSDSVLSFDFF-IYPVPYSHPIIMFTYYAAQLGIALSVVD 228
[Close]
BLAST of Transmembrane protein 86A vs. Ensembl Cavefish
Match: tmem86a (transmembrane protein 86A [Source:NCBI gene;Acc:103022453])

HSP 1 Score: 130.568 bits (327), Expect = 3.991e-36
Identity = 78/224 (34.82%), Postives = 126/224 (56.25%), Query Frame = 2 
Query:   86 LLKSVIPLLIPFFKTSALYFILSNHLSESKILFSILKCTPIITLLIFVISRCYISRCFSSYRILVSAGLILSCIGDVFLVYKPEGYLIHGIVAFGIAQVIYTCAFGFRQFK---GKIAGALFACGVCIYRLIYPNLTGILVIACPIYMSMLGCMIWRATSRAEWSNRELCTSKLLPAIGSILFMISDIILALSLFHVITFTGCGNAIMFTYYAAQMFIALSCTD 748
            ++KS  P L+PFFK + +YF+L    S      +++KC PI  L +F+++  +      S    + AGLI S +GD FL+++ +GY  HG++ F I  ++Y+ AFG +      G + G +   G+C Y L+YP L G       +Y++++G M WRA +  + +N     +KL   +G++LFM+SD+ +A++ F           IM TYYAAQM IALS  +
Sbjct:    7 VVKSEGPKLVPFFKATCVYFVLWLPTSSPSWFSALIKCLPIFCLWVFLLAHGFSFLGAHSNARKILAGLIFSALGDAFLIWQEQGYFSHGLLMFAITHILYSSAFGMKPLNLRAGLVIGTI--SGLC-YTLLYPYLAGPFTYLVAVYIALIGFMGWRAIAGVQLANDLWTWTKLSACLGAVLFMVSDLTIAVNKF-CFPVPHSRAIIMATYYAAQMLIALSAVE 226
[Close]
BLAST of Transmembrane protein 86A vs. Ensembl Cavefish
Match: tmem86b (lysoplasmalogenase-like [Source:NCBI gene;Acc:103023220])

HSP 1 Score: 53.1434 bits (126), Expect = 8.563e-8
Identity = 62/221 (28.05%), Postives = 106/221 (47.96%), Query Frame = 2 
Query:  110 LIPFFKTSALYFILSNHLSESKILFSILKCTPIITLLIFVIS-RCYISRCFSSYRILVSAGLILSCIGDVFLVYKPEGYLIHGIVAFGIAQVIYTCAFGFRQFKGKIAGALFACGVCIYRLIYPNLTGILVI----------ACPIYMSMLGCMIWRATSRAEWSNRELCTSKLLPAIGSILFMISDIILALSLFHVITFTGCGNAI-MFTYYAAQMFIAL 736
            L+PFF ++AL+F L    S   +L + +K  P+I+L + V+S     S    +  +L+S+G      GD+ L++   G  +HG+  F +A ++Y+ +F   ++    A +  + G+ I  L+   +TG   +             I++  +G   +     A    R   T   L  +G ++FM SD+ LAL  F V+     G  I M TYY AQ+ IA+
Sbjct:   25 LLPFFASAALFFYLWIPESTPSLLAAGVKAVPVISLALMVLSYNGGRSLLGVAGGLLLSSG------GDICLIWP--GLFLHGMGFFALAHLMYSLSFLSSRYT---AHSYPSSGIYIVYLLQWGITGAAYVYLLPFLQNSPEPNIFVPAVGAYAFLIVLMATLGAR---TRHSLVMLGGLVFMTSDLSLALQHFKVVESLEYGRHIVMITYYLAQLLIAV 231
[Close]
BLAST of Transmembrane protein 86A vs. Ensembl Nematostella
Match: EDO48808 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RIH1])

HSP 1 Score: 112.079 bits (279), Expect = 3.094e-29
Identity = 84/225 (37.33%), Postives = 119/225 (52.89%), Query Frame = 2 
Query:   80 APLLKSVIPLLIPFFKTSALYFILSNHLSESKILFS-ILKCTPIITLLIFVISRCYISRCFSSYRILVSAGLILSCIGDVFLVYKPEGYLIHGIVAFGIAQVIYTCAFGFRQFKGKIAGALFACGVCIYRLIYPNLTGILVIACPIYMSMLGCMIWRATSRAE---WSNRELCT-SKLLPAIGSILFMISDIILALSLFHVITFTGCGNAIMFTYYAAQMFIALS 739
            A +LK+  P L+PFFKT  +YF+     S+   +F+ +LK  PI  L  FV  +         Y   +  GLI S IGDV LV+K   Y IHG+VAF IA ++Y  +FGFR  K           +  Y   +PNL G+L  A P+Y+ ++G M+WRA +  +   +S+  L   +KL   +G++ F ISD  + L+ F           IMFTYY  Q+ IALS
Sbjct:   28 ADVLKTAGPKLVPFFKTVCVYFVAWLPESDRPTIFAALLKILPIACLCGFVTLQGVSLTKQHDYSRRILLGLIFSMIGDVCLVWK-HSYFIHGMVAFAIAHLLYMRSFGFRPLKPLTGIICLLLMLPFYVFYFPNLKGLLFYAVPVYIVVIGIMVWRAITGLQAQIYSDDGLWRWTKLCACLGALSFAISDAAIGLNKF-CFPIPHSRAIIMFTYYGGQLGIALS 250
[Close]
BLAST of Transmembrane protein 86A vs. Ensembl Medaka
Match: tmem86a (transmembrane protein 86A [Source:NCBI gene;Acc:101161706])

HSP 1 Score: 135.576 bits (340), Expect = 4.685e-38
Identity = 75/221 (33.94%), Postives = 124/221 (56.11%), Query Frame = 2 
Query:   86 LLKSVIPLLIPFFKTSALYFILSNHLSESKILFSILKCTPIITLLIFVISRCYISRCFSSYRILVSAGLILSCIGDVFLVYKPEGYLIHGIVAFGIAQVIYTCAFGFRQFKGKIAGALFACGVCIYRLIYPNLTGILVIACPIYMSMLGCMIWRATSRAEWSNRELCTSKLLPAIGSILFMISDIILALSLFHVITFTGCGNAIMFTYYAAQMFIALSCTD 748
            ++KS  P L+PFFK + +YF+L    S      +++KC PI  L +F+++      C  +    + AGLI S +GD FL+++ +GY +HG++ F +  ++Y+ AFG +    +    + A     Y L+YP L+G       +YM+++G M WRA +  + +N     +KL   +G++LFM+SD+ +A++ F           IM TYYAAQM IALS  +
Sbjct:    7 VVKSEGPKLVPFFKATCVYFVLWLPTSSPSWFSALIKCLPIFCLWVFLLAHGSGFLCAHADARKILAGLIFSALGDAFLIWQEQGYFVHGLLMFAVTHILYSSAFGMKPLNVRAGLLMAAVSFLTYVLLYPYLSGPFTYLVAVYMALIGFMGWRAVAGLQLANDLWTWTKLSACLGAVLFMVSDLTIAVNKF-CFPVPHSRAIIMATYYAAQMLIALSAVE 226
[Close]
BLAST of Transmembrane protein 86A vs. Planmine SMEST
Match: SMESG000038930.1 (SMESG000038930.1)

HSP 1 Score: 465.692 bits (1197), Expect = 5.415e-168
Identity = 234/236 (99.15%), Postives = 235/236 (99.58%), Query Frame = 2 
Query:   53 MVSYISAKSAPLLKSVIPLLIPFFKTSALYFILSNHLSESKILFSILKCTPIITLLIFVISRCYISRCFSSYRILVSAGLILSCIGDVFLVYKPEGYLIHGIVAFGIAQVIYTCAFGFRQFKGKIAGALFACGVCIYRLIYPNLTGILVIACPIYMSMLGCMIWRATSRAEWSNRELCTSKLLPAIGSILFMISDIILALSLFHVITFTGCGNAIMFTYYAAQMFIALSCTDPLSI 760
            MVSYISAKSAPLLKSVIPLLIPFFKTSALYFILSNHLSESKILFSILKCTPIITLLIFVISRCY+SRCFSSYRILVSAGLILSCIGDVFLVYKPEGYLIHGIVAFGIAQVIYTCAFGFRQFKGKIAGALF CGVCIYRLIYPNLTGILVIACPIYMSMLGCMIWRATSRAEWSNRELCTSKLLPAIGSILFMISDIILALSLFHVITFTGCGNAIMFTYYAAQMFIALSCTDPLSI
Sbjct:    1 MVSYISAKSAPLLKSVIPLLIPFFKTSALYFILSNHLSESKILFSILKCTPIITLLIFVISRCYVSRCFSSYRILVSAGLILSCIGDVFLVYKPEGYLIHGIVAFGIAQVIYTCAFGFRQFKGKIAGALFVCGVCIYRLIYPNLTGILVIACPIYMSMLGCMIWRATSRAEWSNRELCTSKLLPAIGSILFMISDIILALSLFHVITFTGCGNAIMFTYYAAQMFIALSCTDPLSI 236
[Close]
BLAST of Transmembrane protein 86A vs. Planmine SMEST
Match: SMESG000010122.1 (SMESG000010122.1)

HSP 1 Score: 126.331 bits (316), Expect = 4.932e-35
Identity = 80/206 (38.83%), Postives = 116/206 (56.31%), Query Frame = 2 
Query:  134 ALYFILSNHLSESKILFSILKCTPIITLLIFVISRCYISRCFSS-YRILVSAGLILSCIGDVFLVYKPEGYLIHGIVAFGIAQVIYTCAFGFRQFKGKIAGALFACGVCIYRLIYPNLTGILVIACPIYMSMLGCMIWRATSRAEWSNRELCTS--KLLPAIGSILFMISDIILALSLFHVITFTGCGNAIMFTYYAAQMFIALSC 742
            A+YFI+S +L E+K+ +S  K  PII+L+  + S+    +C  + Y  L+S GL+ S IGDVFLV++ +GYL HG + F IA + Y  AFGF  FK  ++       +  Y   Y    GI  I  P+YM ++  M WR  S+   +   L     KL  A G I F++SD+IL   +F +I+F   G  +M TYYAAQ  +A+S 
Sbjct:    3 AIYFIVSYNLEENKVFYSCAKIAPIISLIFILQSQ----KCMKTKYVYLISLGLLFSAIGDVFLVWRTKGYLTHGTLFFSIAHLAYLVAFGFNPFKILLSIPFLIIAIVSYSCTYHLFYGINAIVLPVYMILVCSMGWRGLSQLHSTASHLVYKHMKLGAAFGGISFVLSDMILCTEIFGLISFPHSGVFVMLTYYAAQFGLAISA 204
[Close]
BLAST of Transmembrane protein 86A vs. Planmine SMEST
Match: SMESG000001487.1 (SMESG000001487.1)

HSP 1 Score: 126.331 bits (316), Expect = 4.932e-35
Identity = 80/206 (38.83%), Postives = 116/206 (56.31%), Query Frame = 2 
Query:  134 ALYFILSNHLSESKILFSILKCTPIITLLIFVISRCYISRCFSS-YRILVSAGLILSCIGDVFLVYKPEGYLIHGIVAFGIAQVIYTCAFGFRQFKGKIAGALFACGVCIYRLIYPNLTGILVIACPIYMSMLGCMIWRATSRAEWSNRELCTS--KLLPAIGSILFMISDIILALSLFHVITFTGCGNAIMFTYYAAQMFIALSC 742
            A+YFI+S +L E+K+ +S  K  PII+L+  + S+    +C  + Y  L+S GL+ S IGDVFLV++ +GYL HG + F IA + Y  AFGF  FK  ++       +  Y   Y    GI  I  P+YM ++  M WR  S+   +   L     KL  A G I F++SD+IL   +F +I+F   G  +M TYYAAQ  +A+S 
Sbjct:    3 AIYFIVSYNLEENKVFYSCAKIAPIISLIFILQSQ----KCMKTKYVYLISLGLLFSAIGDVFLVWRTKGYLTHGTLFFSIAHLAYLVAFGFNPFKILLSIPFLIIAIVSYSCTYHLFYGINAIVLPVYMILVCSMGWRGLSQLHSTASHLVYKHMKLGAAFGGISFVLSDMILCTEIFGLISFPHSGVFVMLTYYAAQFGLAISA 204
The following BLAST results are available for this feature:
BLAST of Transmembrane protein 86A vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 2
Match NameE-valueIdentityDescription
TMEM86A3.388e-3133.04transmembrane protein 86A [Source:HGNC Symbol;Acc:... [more]
TMEM86B1.430e-1028.04transmembrane protein 86B [Source:HGNC Symbol;Acc:... [more]
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BLAST of Transmembrane protein 86A vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Transmembrane protein 86A vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 2
Match NameE-valueIdentityDescription
CG75821.694e-2431.93gene:FBgn0039681 transcript:FBtr0085464[more]
CG75823.379e-1737.40gene:FBgn0039681 transcript:FBtr0308238[more]
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BLAST of Transmembrane protein 86A vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 3
Match NameE-valueIdentityDescription
CT573392.29.432e-3734.53pep chromosome:GRCz11:CHR_ALT_CTG25_1_21:24252904:... [more]
tmem86a2.830e-3634.08transmembrane protein 86A [Source:ZFIN;Acc:ZDB-GEN... [more]
tmem86b8.417e-828.51transmembrane protein 86B [Source:ZFIN;Acc:ZDB-GEN... [more]
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BLAST of Transmembrane protein 86A vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 3
Match NameE-valueIdentityDescription
tmem86a1.256e-2932.87transmembrane protein 86A [Source:NCBI gene;Acc:10... [more]
tmem86a1.332e-2932.87transmembrane protein 86A [Source:NCBI gene;Acc:10... [more]
tmem86a4.530e-2933.02transmembrane protein 86A [Source:NCBI gene;Acc:10... [more]
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BLAST of Transmembrane protein 86A vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 3
Match NameE-valueIdentityDescription
Tmem86a1.255e-3133.91transmembrane protein 86A [Source:MGI Symbol;Acc:M... [more]
Tmem86b1.100e-1128.17transmembrane protein 86B [Source:MGI Symbol;Acc:M... [more]
Tmem86b1.144e-1128.17transmembrane protein 86B [Source:MGI Symbol;Acc:M... [more]
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BLAST of Transmembrane protein 86A vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|Q3MHQ7|TM86A_BOVIN1.291e-3335.40Lysoplasmalogenase-like protein TMEM86A OS=Bos tau... [more]
sp|Q9D8N3|TM86A_MOUSE8.776e-3133.91Lysoplasmalogenase-like protein TMEM86A OS=Mus mus... [more]
sp|Q8N2M4|TM86A_HUMAN1.627e-3033.04Lysoplasmalogenase-like protein TMEM86A OS=Homo sa... [more]
sp|F1RMN2|TM86B_PIG6.374e-1729.11Lysoplasmalogenase OS=Sus scrofa OX=9823 GN=TMEM86... [more]
sp|Q3T0W0|TM86B_BOVIN7.062e-1630.37Lysoplasmalogenase OS=Bos taurus OX=9913 GN=TMEM86... [more]
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BLAST of Transmembrane protein 86A vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
A0A482XSI83.575e-3939.73Uncharacterized protein OS=Laodelphax striatellus ... [more]
A0A1S3JIA16.540e-3839.65lysoplasmalogenase-like protein TMEM86A OS=Lingula... [more]
R7UKM03.135e-3737.17Uncharacterized protein OS=Capitella teleta OX=283... [more]
A0A433U7W03.514e-3737.72Uncharacterized protein (Fragment) OS=Elysia chlor... [more]
A0A3M7PMA48.094e-3740.18Lysoplasmalogenase TMEM86A OS=Brachionus plicatili... [more]
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BLAST of Transmembrane protein 86A vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 2
Match NameE-valueIdentityDescription
tmem86a3.991e-3634.82transmembrane protein 86A [Source:NCBI gene;Acc:10... [more]
tmem86b8.563e-828.05lysoplasmalogenase-like [Source:NCBI gene;Acc:1030... [more]
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BLAST of Transmembrane protein 86A vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Transmembrane protein 86A vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Transmembrane protein 86A vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 1
Match NameE-valueIdentityDescription
EDO488083.094e-2937.33Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
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BLAST of Transmembrane protein 86A vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 1
Match NameE-valueIdentityDescription
tmem86a4.685e-3833.94transmembrane protein 86A [Source:NCBI gene;Acc:10... [more]
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BLAST of Transmembrane protein 86A vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 3
Match NameE-valueIdentityDescription
SMESG000038930.15.415e-16899.15SMESG000038930.1[more]
SMESG000010122.14.932e-3538.83SMESG000010122.1[more]
SMESG000001487.14.932e-3538.83SMESG000001487.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30014236 ID=SMED30014236|Name=Transmembrane protein 86A|organism=Schmidtea mediterranea sexual|type=transcript|length=907bp
ATAAGATCTAATTTTCATCTCTCTTTAAAAATTTTGACTTCATATTTAAA
AAATGGTTAGCTATATAAGTGCGAAGTCAGCTCCATTGTTGAAATCAGTC
ATCCCATTACTCATCCCATTCTTCAAAACATCAGCATTATATTTCATTTT
GTCAAATCATCTTAGTGAATCTAAAATATTATTTTCCATTCTGAAATGCA
CTCCAATTATAACGTTACTTATATTCGTCATATCTAGATGTTATATTTCC
CGATGCTTTAGCAGTTATCGTATTTTAGTATCGGCGGGGTTGATTTTATC
GTGCATTGGTGATGTATTTCTAGTATATAAACCTGAAGGTTATCTGATTC
ATGGAATCGTTGCATTTGGAATCGCCCAAGTGATTTATACTTGTGCATTT
GGTTTTCGACAATTTAAAGGCAAAATTGCTGGTGCTTTATTTGCGTGTGG
TGTCTGCATTTATAGATTAATCTATCCAAATTTAACGGGAATTCTTGTTA
TTGCCTGTCCGATTTATATGTCTATGCTTGGTTGCATGATATGGAGGGCA
ACTTCACGGGCTGAATGGTCGAATCGAGAATTATGTACTTCCAAGCTGTT
ACCGGCTATAGGATCAATTTTATTTATGATTTCAGATATTATTTTGGCAT
TGTCTTTATTTCATGTGATAACATTTACCGGCTGTGGTAATGCTATTATG
TTCACGTATTATGCAGCTCAGATGTTTATTGCGCTGTCATGTACCGATCC
GCTTTCCATTTAATATATTGTTATATTTCCTTTAGTTTTCTAGTATTCAT
GTTGTGGTTTCCTAATCATTTTTTCATATTTATATTGGTAAAATTTGTTT
AGTTGTCGAAAAGTATTATTTGCATCATTTTGGAGAAGTTTTTATTTTTT
ATTGTCT
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protein sequence of SMED30014236-orf-1

>SMED30014236-orf-1 ID=SMED30014236-orf-1|Name=SMED30014236-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=237bp
MVSYISAKSAPLLKSVIPLLIPFFKTSALYFILSNHLSESKILFSILKCT
PIITLLIFVISRCYISRCFSSYRILVSAGLILSCIGDVFLVYKPEGYLIH
GIVAFGIAQVIYTCAFGFRQFKGKIAGALFACGVCIYRLIYPNLTGILVI
ACPIYMSMLGCMIWRATSRAEWSNRELCTSKLLPAIGSILFMISDIILAL
SLFHVITFTGCGNAIMFTYYAAQMFIALSCTDPLSI*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000020protonephridia
PLANA:0000034epidermis
Vocabulary: INTERPRO
TermDefinition
IPR012506YhhN
Vocabulary: cellular component
TermDefinition
GO:0016021integral component of membrane
GO:0016020membrane
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR012506YhhN-likePFAMPF07947YhhNcoord: 45..229
e-value: 6.7E-37
score: 126.9
IPR012506YhhN-likePANTHERPTHR31885FAMILY NOT NAMEDcoord: 14..232
NoneNo IPR availablePANTHERPTHR31885:SF6TRANSMEMBRANE PROTEIN 86Acoord: 14..232
NoneNo IPR availableTMHMMTMhelixcoord: 69..91
NoneNo IPR availableTMHMMTMhelixcoord: 125..142
NoneNo IPR availableTMHMMTMhelixcoord: 147..164
NoneNo IPR availableTMHMMTMhelixcoord: 96..118
NoneNo IPR availableTMHMMTMhelixcoord: 13..32
NoneNo IPR availableTMHMMTMhelixcoord: 42..64
NoneNo IPR availableTMHMMTMhelixcoord: 185..207