Myeloid differentiation primary response protein MyD88
Overview
Neoblast Clusters
Zeng et. al., 2018▻ Overview▻ Neoblast Population▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Overview
Single cell RNA-seq of pluripotent neoblasts and its early progeniesWe isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)Explore this single cell expression dataset with our NB Cluster Shiny App
Neoblast Population
Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Embryonic Expression
Davies et. al., 2017
Hover the mouse over a column in the graph to view average RPKM values per sample. Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult. back to top Anatomical Expression
PAGE et. al., 2020SMED30014235 has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGEPAGE Curations: 6
Homology
BLAST of Myeloid differentiation primary response protein MyD88 vs. Ensembl Zebrafish
Match: myd88 (MYD88 innate immune signal transduction adaptor [Source:NCBI gene;Acc:403145]) HSP 1 Score: 55.8398 bits (133), Expect = 2.970e-8 Identity = 57/262 (21.76%), Postives = 116/262 (44.27%), Query Frame = 3 Query: 297 SVPIHALSEKCKEKLKFLDCTFIIPDTEVKLRDYRGLAVLLNYSTLELNYLIDQKRYTSPTYLILDRMKMEKRTFLDLYCCLKKLKRSDIIDNCREELTRDAMEFLKKTGKFLFEHVNQEAFKQITSPTELDEAKKTIGKLFTTDIIETANRQIDIYDVFISFESESIDDIKIMWLISGRLESR--GLTVAKGSYSFIQGVCINEAFANAIYNRSKKVILLISKAFINSESCLMQLNFARDADRASRRNKIIPVYIEEVKKP 1076 ++P+ AL+ ++KL F+ P V D+R +A L++++ LE+ +KR ++ D T +L L+K +R D+I +E L D +++++ + K + P +T + T + + +D FI + DI+ + + +LE L + + G C+ + I R K+++++IS +++S++C Q FA +R ++IPV + +K+P Sbjct: 11 AIPVTALNCSFRKKLGL----FLNPTNTVAA-DWRTVAELMDFTYLEIKNF--EKRECPFEKVLTDWETRPDATVANLLSILEKAERKDVISELKEILDDDCRKYMERQQR-----------KPLQVPVVDSCGPRTQEREGITLYDDPQGLTPETFDAFICY---CQSDIQFVHEMIKQLEHTEYNLKLCVFDRDVLPGTCVWTIASELIEKRCKRMVVVISDDYLDSDACDFQTKFALSLCPGARTKRLIPVVYKSMKRP 251
BLAST of Myeloid differentiation primary response protein MyD88 vs. Ensembl Xenopus
Match: myd88 (myeloid differentiation primary response 88 [Source:NCBI gene;Acc:549591]) HSP 1 Score: 51.6026 bits (122), Expect = 1.264e-6 Identity = 67/298 (22.48%), Postives = 129/298 (43.29%), Query Frame = 3 Query: 291 FSSVPIHALSEKCKEKLKFLDCTFIIPDTEVKLRDYRGLAVLLNYSTLELNYLIDQKRYTSPTYLILDRM--KMEKRTFLDLYCCLKKLKRSDIIDNCREELTRDAMEFLKKTGKFLFEHVNQEAFKQITSPTELDEAKKTIGKLFTTDIIETANRQIDIYDVFISFESESIDDIKIMWLISGRLESRG--LTVAKGSYSFIQGVCINEAFANAIYNRSKKVILLISKAFINSESCLMQLNFARDADRASRRNKIIPVYIEEVKKPECIASINGF----NYYNNSIREMFFDSFINSF 1160 +S+P+ AL+ + +L ++ P+ V + LA + Y LE+ +R+ T +L+ K + T L LKK++R+DI+ + + D M+ L+K L ++ + T+ D+ ++ + F D FI + ++ I ++ M IS RLE L + + G C+ + I +R +K++++IS +++S C Q FA +R ++IPV + +K+P SI F +Y N + F++ + Sbjct: 12 MNSIPLVALNYNVRHRLSL----YLNPNAVVA-AGWTQLAEEMGYDYLEIKNF---ERFPDCTMKLLEDWEKKCFRATVGGLLEMLKKMERNDILTDLGPLIEADCMKHLEKKNAPLPLQDDKVDSSEQYRITKSDDPSGSLPETF---------------DAFICYCAQDISFVQEM--IS-RLEQTDYKLKLCVFDRDVLPGTCLWSITSELIEHRCRKMVVIISDDYLDSSECDFQTKFALSLGPGAREKRLIPVKYKPMKRP--FPSILRFITLCDYTNPCTKGWFWERLAKAL 281
BLAST of Myeloid differentiation primary response protein MyD88 vs. UniProt/SwissProt
Match: sp|Q9DF60|MY88A_XENLA (Myeloid differentiation primary response protein MyD88-A OS=Xenopus laevis OX=8355 GN=myd88-a PE=2 SV=1) HSP 1 Score: 67.0106 bits (162), Expect = 5.516e-11 Identity = 69/296 (23.31%), Postives = 129/296 (43.58%), Query Frame = 3 Query: 291 FSSVPIHALSEKCKEKLKFLDCTFIIPDTEVKLRDYRGLAVLLNYSTLELNYLIDQKRYTSPTYLILDRM--KMEKRTFLDLYCCLKKLKRSDIIDNCREELTRDAMEFLKKTGKFLFEHVNQEAFKQITSPTELDEAKKTIGKLFTTDIIETANRQIDIYDVFISFESESIDDIKIMWLISGRLESRG--LTVAKGSYSFIQGVCINEAFANAIYNRSKKVILLISKAFINSESCLMQLNFARDADRASRRNKIIPVYIEEVKK--PECIASINGFNYYNNSIREMFFDSFINSF 1160 +S+P+ AL+ + +L C ++ PD V D+ LA + Y LE+ +RY T +L+ K + T L LKK++R+DI+ + + D M++L+K K + P + D+ + + T + + +D FI + ++ I ++ M RLE L + + G C+ + I NR +K++++IS +++S C Q FA +R ++IPV + +K+ P + I +Y N + F+D + Sbjct: 12 MNSIPLVALNYTVRHRL----CLYLNPDAVVA-ADWTRLAEEMGYDYLEIRNF---QRYPDSTMKLLEDWEKKCFRATVGGLLEMLKKMERNDILTDLGPLIEADCMKYLEK--------------KHVPLPIQDDKVDSS-EQYRITKSDDPYGSMPETFDAFICYCAQDISFVQEM---ISRLEQTDYKLKLCVFDRDVLPGTCLWSITSELIENRCRKMVVIISDDYLDSSDCDFQTKFALSLGPGAREKRLIPVKYKPMKRPFPSILRFITVCDYTNPYTKAWFWDKLAKAL 281
BLAST of Myeloid differentiation primary response protein MyD88 vs. UniProt/SwissProt
Match: sp|Q5FWM2|MY88B_XENLA (Myeloid differentiation primary response protein MyD88-B OS=Xenopus laevis OX=8355 GN=myd88-b PE=2 SV=1) HSP 1 Score: 58.151 bits (139), Expect = 3.935e-8 Identity = 67/273 (24.54%), Postives = 122/273 (44.69%), Query Frame = 3 Query: 273 MNISDYFSSVPIHALSEKCKEKLKFLDCTFIIPDTEVKLRDYRGLAVLLNYSTLELNYLIDQKRYTSPTYLILD--RMKMEKRTFLDLYCCLKKLKRSDIIDNCREELTRDAMEFL-KKTGKFLFEHVNQEAFKQITSPTELDEAKKTIGKLFTTDIIETANRQIDIYDVFISFESESIDDIKIMWLISGRLESRG--LTVAKGSYSFIQGVCINEAFANAIYNRSKKVILLISKAFINSESCLMQLNFARDADRASRRNKIIPVYIEEVKKP 1076 MN D +S+P+ AL+ + +L C ++ P+ V D+ LA + Y LE+ RY T +L+ + K + T L LKK++R+DI+ + + D ++L KK G + N ++ +Q + ++ G + T +D FI ++ DI + + RLE L + + G C+ + I NR +K++++IS +++S C Q FA +R ++IPV + +K+P Sbjct: 7 MNSFD-MNSIPLVALNYTVRHRL----CLYLNPNAVVA-ADWTRLAEEMGYDYLEIRNF---DRYPDSTMKLLEDWQKKCFRATVGGLLEMLKKMERNDILTDLAPLIEADCKKYLEKKHGPLPLQDDNVDSSEQY----RITKSDDPYGSMPET------------FDAFICCCAQ---DILFVQEMISRLEQTDYKLKLCVFDRDVLPGTCLWSITSELIENRCRKMVVIISDDYLDSSECDFQTKFALSLGPGAREKRLIPVKYKPMKRP 251
BLAST of Myeloid differentiation primary response protein MyD88 vs. UniProt/SwissProt
Match: sp|Q5XJ85|MYD88_DANRE (Myeloid differentiation primary response protein MyD88 OS=Danio rerio OX=7955 GN=myd88 PE=2 SV=2) HSP 1 Score: 55.8398 bits (133), Expect = 2.764e-7 Identity = 57/262 (21.76%), Postives = 116/262 (44.27%), Query Frame = 3 Query: 297 SVPIHALSEKCKEKLKFLDCTFIIPDTEVKLRDYRGLAVLLNYSTLELNYLIDQKRYTSPTYLILDRMKMEKRTFLDLYCCLKKLKRSDIIDNCREELTRDAMEFLKKTGKFLFEHVNQEAFKQITSPTELDEAKKTIGKLFTTDIIETANRQIDIYDVFISFESESIDDIKIMWLISGRLESR--GLTVAKGSYSFIQGVCINEAFANAIYNRSKKVILLISKAFINSESCLMQLNFARDADRASRRNKIIPVYIEEVKKP 1076 ++P+ AL+ ++KL F+ P V D+R +A L++++ LE+ +KR ++ D T +L L+K +R D+I +E L D +++++ + K + P +T + T + + +D FI + DI+ + + +LE L + + G C+ + I R K+++++IS +++S++C Q FA +R ++IPV + +K+P Sbjct: 11 AIPVTALNCSFRKKLGL----FLNPTNTVAA-DWRTVAELMDFTYLEIKNF--EKRDCPFEKVLTDWETRPDATVANLLSILEKAERKDVISELKEILDDDCRKYMERQQR-----------KPLQVPVVDSCGPRTQEREGITLYDDPQGLTPETFDAFICY---CQSDIQFVHEMIKQLEHTEYNLKLCVFDRDVLPGTCVWTIASELIEKRCKRMVVVISDDYLDSDACDFQTKFALSLCPGARTKRLIPVVYKSMKRP 251
BLAST of Myeloid differentiation primary response protein MyD88 vs. UniProt/SwissProt
Match: sp|Q28DJ2|MYD88_XENTR (Myeloid differentiation primary response protein MyD88 OS=Xenopus tropicalis OX=8364 GN=myd88 PE=2 SV=1) HSP 1 Score: 51.6026 bits (122), Expect = 5.688e-6 Identity = 67/298 (22.48%), Postives = 129/298 (43.29%), Query Frame = 3 Query: 291 FSSVPIHALSEKCKEKLKFLDCTFIIPDTEVKLRDYRGLAVLLNYSTLELNYLIDQKRYTSPTYLILDRM--KMEKRTFLDLYCCLKKLKRSDIIDNCREELTRDAMEFLKKTGKFLFEHVNQEAFKQITSPTELDEAKKTIGKLFTTDIIETANRQIDIYDVFISFESESIDDIKIMWLISGRLESRG--LTVAKGSYSFIQGVCINEAFANAIYNRSKKVILLISKAFINSESCLMQLNFARDADRASRRNKIIPVYIEEVKKPECIASINGF----NYYNNSIREMFFDSFINSF 1160 +S+P+ AL+ + +L ++ P+ V + LA + Y LE+ +R+ T +L+ K + T L LKK++R+DI+ + + D M+ L+K L ++ + T+ D+ ++ + F D FI + ++ I ++ M IS RLE L + + G C+ + I +R +K++++IS +++S C Q FA +R ++IPV + +K+P SI F +Y N + F++ + Sbjct: 12 MNSIPLVALNYNVRHRLSL----YLNPNAVVA-AGWTQLAEEMGYDYLEIKNF---ERFPDCTMKLLEDWEKKCFRATVGGLLEMLKKMERNDILTDLGPLIEADCMKHLEKKNAPLPLQDDKVDSSEQYRITKSDDPSGSLPETF---------------DAFICYCAQDISFVQEM--IS-RLEQTDYKLKLCVFDRDVLPGTCLWSITSELIEHRCRKMVVIISDDYLDSSECDFQTKFALSLGPGAREKRLIPVKYKPMKRP--FPSILRFITLCDYTNPCTKGWFWERLAKAL 281
BLAST of Myeloid differentiation primary response protein MyD88 vs. TrEMBL
Match: A0A0A7NVN0 (MYD88 OS=Cyclina sinensis OX=120566 PE=2 SV=1) HSP 1 Score: 93.2041 bits (230), Expect = 1.405e-16 Identity = 78/300 (26.00%), Postives = 139/300 (46.33%), Query Frame = 3 Query: 276 NISDYFSSVPIHALSEKCKEKLKF-LDCTFIIPDTEVKLRDYRGLAVLLNYSTLELNYLIDQKRYTSPTYLILDRMKME---KRTFLDLYCCLKKLKRSDIIDNCREELTRDAMEFLKKTGKFLFEHVN-QEAFKQITSPTELDEAKKTIGKLFTTDIIETANRQIDIYDVFISFESESIDDIKIMWLISGRLESRGLTVAKGSYSFIQGVCINEAFANAIYNRSKKVILLISKAFINSESCLMQLNFARDADRASRRNKIIPVYIEEVKKPECIASINGFNYYNNSIREMFFDSFINSF 1160 ++S +S +P+ AL+ C+ ++ L+ + + + + DYRGLA L+ ++ LE+ +R SPT +L T L+ L L+R D++ + ++ + RD ++L+ +F + Q+ T ++DE+ LF + + + + IYD F+ + E D + LI GL + + G N A I R K++I+++S +++ S +C Q FA SR K+IPV IE+ PE I + NY +RE F+ I+S Sbjct: 10 DLSSKYSVIPLEALNASCRRQIALHLNLEGTMNEDNI-INDYRGLAELVGFNYLEIKNF---ERNNSPTEQLLSDWTTRTDLSPTVGTLWKNLLSLERVDVLTDSKKYIERDCEKYLEIKARFQTSQIPVQDNTVSQTPDHDVDES------LFM-GVDDVIHGKPTIYDAFVCYNPEGKDLAFVRQLIQKLEVENGLKLFVPWRDDLPGASHNTVCAKLIEYRCKRMIIILSPSYLQSPACDFQTKFAHGLSPGSRNKKLIPVLIEDCVIPEIIRHVTCCNYTKKDLREWFWSRLISSL 298
BLAST of Myeloid differentiation primary response protein MyD88 vs. TrEMBL
Match: A0A3G1HV23 (Myeloid differentiation factor 88 OS=Anadara sativa OX=1028096 PE=2 SV=1) HSP 1 Score: 89.7373 bits (221), Expect = 1.518e-15 Identity = 75/298 (25.17%), Postives = 143/298 (47.99%), Query Frame = 3 Query: 273 MNISDYFSSVPIHALSEKCKEKL-KFLDCTFIIPDTEVKLRDYRGLAVLLNYSTLELNYLIDQKRYTSPTYLILDRMKME---KRTFLDLYCCLKKLKRSDIIDNCREELTRDAMEFLKKTGKFLFEH--VNQEAFKQITSPTELDEAKKTIGKLFTTDIIETANRQIDIYDVFISFESESIDDIKIMWLISGRLESR-GLTVAKGSYSFIQGVCINEAFANAIYNRSKKVILLISKAFINSESCLMQLNFARDADRASRRNKIIPVYIE-EVKKPECIASINGFNYYNNSIREMFFD 1142 M++SD + +P+ L+ + KL K+L+ + + DY GLA L+ + L++ +R SPT +LD K T +L+ L +L R D++++C + + RD FL++ KF E+ V ++ Q T +T+ + + D +E + YD F+ + E D+K + + LE++ L + + G A I +R +++++++S+ ++ S +C Q+ FA +R K+IPV IE VK P+ + + ++ + E F+D Sbjct: 14 MSLSDQYKEIPLDGLNISSRRKLAKYLNIPAEFHEDSGHIGDYSGLAELIGFDYLDIKNF---ERQKSPTEEVLDAWSQRADFKPTIGNLWKYLIELGRLDVLEDCEQSIRRDIEGFLQRRAKFQDEYKPVQEDTVSQSTETAPDHHVNETL--ILSKDDVEG---HLQFYDAFVCYNPEG-GDVKFVKEMIKMLENKYKLKLFVPYRDDLPGGARYVMDAKLIESRCRRMVIIMSQNYMKSSACDFQVKFAHALSPGARSKKLIPVLIESSVKIPQILRHVTLCDFTKQDLMEWFWD 302
BLAST of Myeloid differentiation primary response protein MyD88 vs. TrEMBL
Match: A0A5C0NSG4 (Myeloid differentiation factor 88 OS=Mimachlamys nobilis OX=106276 GN=Myd88 PE=4 SV=1) HSP 1 Score: 87.4261 bits (215), Expect = 4.445e-15 Identity = 75/312 (24.04%), Postives = 143/312 (45.83%), Query Frame = 3 Query: 300 VPIHALSEKCKEKLKFL--DCTFIIPDTEVKLRDYRGLAVLLNYSTLELNYLIDQKRYTSPTYLILDRM---KMEKRTFLDLYCCLKKLKRSDIIDNCREELTRDAMEFLKKTGKFLFEHVNQEAFKQITSPTELDEAKKTIGKLFTTDIIETANRQIDIYDVFISFESESIDDIKIMWLISGRLESR--GLTVAKGSYSFIQGVCINEAFANAIYNRSKKVILLISKAFINSESCLMQLNFARDADRASRRNKIIPVYIEEVKKPECIASINGFNYYNNSIREMFFDSFINSF*TVLHGMSRTILYDFLSY 1214 V + +L+ C+ K+ L +IPD+++ D+ G A LLN+S E+ L KR+ SPT +L K + T +L L +L+R D+I +CR + RD ++ K+ K + + N F+ L+ + + E YD F+ + ++ D + + +SG LE L + ++ G ++ A I + ++ +++SK+F NS + QL FA +R+ ++IP+ IE+++ P + + +YN IR + + + L T L ++ ++ Sbjct: 17 VKLKSLNNGCRRKIGMLLDPEGSLIPDSDM-FNDWGGYAELLNFSQPEIENL---KRHKSPTQEMLHLWTTRKYPEPTVGNLIRFLYQLERVDVITDCRNMIERDVKKW-KENEKSIEDMYNDPTFRD----PNLNATSNPPSRKTPESVPEVEREHEMYYDCFVIYNPDAPDQLDFVKEMSGILEGPEYNLRLFIPWRDYLVGTAMHSVSAAIIEKKCRRCAVILSKSFNNSPAADFQLKFAHALSPGARQKRVIPIVIEKMEVPNILNFVAPAPFYNVGIRHWQWPRVAATIKSELLPDPETWLPEYDAW 319
BLAST of Myeloid differentiation primary response protein MyD88 vs. TrEMBL
Match: A0A0H3Y827 (MyD88-1 OS=Mizuhopecten yessoensis OX=6573 PE=2 SV=1) HSP 1 Score: 87.0409 bits (214), Expect = 7.267e-15 Identity = 75/298 (25.17%), Postives = 140/298 (46.98%), Query Frame = 3 Query: 276 NISDYFSSVPIHALSEKCKEKLK-FLDC-TFIIPDTEVKLRDYRGLAVLLNYSTLELNYLIDQKRYTSPTYLILDRMKMEKRTFLDLYCCLKKLKRSDIIDNCREELTRDAMEFLKKTGKFLFEHVNQEAFKQI-TSPTELDEAKKTIGKLFTTDIIETANRQIDIY-DVFISFESESIDDIKIMWLISGRLESRGLTVAKGSYSF---------IQGVCINEAFANAIYNRSKKVILLISKAFINSESCLMQLNFARDADRASRRNKIIPVYIEEVKKPECIASINGFNYYNNSIRE 1130 N+ + V +++L+ C+ K+ F+D +IPD+++ D+ G A LLN+S E+ + QK T + + T +L L +L+R D+I CR+ + RD ++ + NQ++ K+I PT D + + + + A Q +IY D F+ + ++ D ++ + +S LE Y+F + G ++ A I + ++ I+++SK+F NS + QL FA +R+ ++IP+ IE V+ P + + +YN IR Sbjct: 8 NLIESMKDVHMNSLNNGCRRKIGMFMDPEGSLIPDSDM-FNDWCGCAELLNFSQPEIENMKRQKSPTQEMLHLWSTRNDPEPTVGNLISFLFQLERFDVISECRQMIERDVKKWKQ----------NQQSLKKIYDDPTFRDPSSPSSPPPDKIETVSDAGSQHEIYYDCFVIYNPDASDQLEFVKEMSRILEG-------PEYNFRLFIPWRDDLVGTAMHSVSAAIIEKKCRRCIVIVSKSFNNSPAADFQLKFAHALSPGARQKRVIPIVIENVEVPSILNFVAPAPFYNVGIRH 287
BLAST of Myeloid differentiation primary response protein MyD88 vs. TrEMBL
Match: A0A2U6KF89 (Myeloid differentiation factor 88 OS=Pinctada fucata OX=50426 PE=2 SV=1) HSP 1 Score: 85.5001 bits (210), Expect = 2.021e-14 Identity = 76/297 (25.59%), Postives = 135/297 (45.45%), Query Frame = 3 Query: 276 NISDYFSSVPIHALSEKCKEKL-KFLDCTFIIPDTEVKLRDYRGLAVLLNYSTLELNYLIDQKRYTSPTYLILDRM--KMEKRTFLD-LYCCLKKLKRSDIIDNCREELTRDAMEFLKKTGKFLFEHVNQEAFKQITSPTELDEAKKTIGKLFTTDIIETANRQ----ID--IYDVFISFESESIDDIKIMWLISGRLESR--GLTVAKGSYSFIQGVCINEAFANAIYNRSKKVILLISKAFINSESCLMQLNFARDADRASRRNKIIPVYIEEVKKPECIASINGFNYYNNSIRE 1130 +I D VP+HAL+ + K+ FLD + T DY GLA + E+ L Q++ PT L + ++ ++D L L+++ R D+ID CR+++ +D ++ K E ++ K+++ E+ K I T RQ ID YD F+ + D+ + ++ RLE GL + + G E A I NR K+ ++++S +F+ S + QL FA+ +R K++PV+ K P + ++N ++ N +R+ Sbjct: 6 SIKDVCKGVPLHALNMAVRNKMASFLDPEGFV--TGDFCNDYTGLAECAGFQYEEIKRLQSQRK---PTLEFLHEWGTRQDRDPYVDVLISHLERIGRPDVIDECRQQIVQDVQKY-----KRCHEDLDPVQSKEVSCGNEVTLYKHEIKSSILTKEEALDPRQACGSIDKLYYDGFVIYNPNGQADLNFVKELADRLEGPEYGLKLFIPFRDDLPGTARYEVTAEIIANRCKRALVILSPSFLQSPAADFQLKFAQCLSPGARSKKVVPVFNGRCKMPNILRAVNFVDFTNPGLRD 292
BLAST of Myeloid differentiation primary response protein MyD88 vs. Ensembl Nematostella
Match: EDO37422 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SFW6]) HSP 1 Score: 45.4394 bits (106), Expect = 3.982e-6 Identity = 35/123 (28.46%), Postives = 60/123 (48.78%), Query Frame = 3 Query: 774 FISFESESIDDIKIMWLISGRLESRGLTVAKGSYSFIQGVCINEAFANAIYNRSKKVILLISKAFINSESCLMQLNFARDADRASRRNKIIPVYIEEVKKPECIASINGFNYYNNSIREMFFD 1142 FI + S+ DIK + RLE+ G F+ G I ANAIY+ S+K + ++S FI SE C +L+ A +R+ R ++++ + E P + +Y N ++ F++ Sbjct: 1 FICYSSK---DIKFAKELQERLENAGFKCCIDLRDFMPGEAIVVNIANAIYH-SRKTLAILSPDFIESEYCKHELHQA--LNRSIRAHQVVAILYRECNVPLELRHKTYLDYLNCYVKPHFWE 117
BLAST of Myeloid differentiation primary response protein MyD88 vs. Ensembl Medaka
Match: myd88 (MYD88 innate immune signal transduction adaptor [Source:NCBI gene;Acc:101168580]) HSP 1 Score: 53.1434 bits (126), Expect = 2.150e-7 Identity = 56/265 (21.13%), Postives = 118/265 (44.53%), Query Frame = 3 Query: 297 SVPIHALSEKCKEKLKFLDCTFIIPDTEVKLRDYRGLAVLLNYSTLEL-NYLIDQKRYTSPTYLILDRMKMEKR--TFLDLYCCLKKLKRSDIIDNCREELTRDAMEFLKKTGKFLFEHVNQEAFKQITSPTELDEAKKTIGKLFTTDIIETANRQIDIYDVFISFESESIDDIKIMWLISGRLES--RGLTVAKGSYSFIQGVCINEAFANAIYNRSKKVILLISKAFINSESCLMQLNFARDADRASRRNKIIPVYIEEVKKP 1076 +VP+ AL+ + KL ++ P V D+ +A + ++ LE+ NY + +PT +L+ + + + L L +++R D++++ R ++ D ++L+ + E Q+ E+D + F + + + +++D FI + DD + + LE L + + G C+ + I R K+++++IS ++ S++C Q FA +R ++IPV + +KKP Sbjct: 12 TVPLVALNVTVRRKLGL----YLNPKNTVAA-DWMTVAEEMGFTYLEIKNY----EASKNPTKTVLEDWQARSKDASVGKLLSILTEVERKDVVEDLRPQIDEDVRKYLESLQR------KSEPPLQVA---EVDSCVPRTPERFGITVEDDPDGSPEMFDAFICY---CQDDFHFVCEMIRELEQTDHKLKLCVFDRDVLPGSCVWTITSELIEKRCKRMVVVISDEYLESDACDFQTKFALSLCPGARNKRLIPVIYKTMKKP 255
BLAST of Myeloid differentiation primary response protein MyD88 vs. Planmine SMEST
Match: SMESG000051766.1 (SMESG000051766.1) HSP 1 Score: 601.282 bits (1549), Expect = 0.000e+0 Identity = 295/296 (99.66%), Postives = 296/296 (100.00%), Query Frame = 3 Query: 273 MNISDYFSSVPIHALSEKCKEKLKFLDCTFIIPDTEVKLRDYRGLAVLLNYSTLELNYLIDQKRYTSPTYLILDRMKMEKRTFLDLYCCLKKLKRSDIIDNCREELTRDAMEFLKKTGKFLFEHVNQEAFKQITSPTELDEAKKTIGKLFTTDIIETANRQIDIYDVFISFESESIDDIKIMWLISGRLESRGLTVAKGSYSFIQGVCINEAFANAIYNRSKKVILLISKAFINSESCLMQLNFARDADRASRRNKIIPVYIEEVKKPECIASINGFNYYNNSIREMFFDSFINSF 1160 MNISDYFSSVPIHALSEKCKEKLKFLDCTFIIPDTE+KLRDYRGLAVLLNYSTLELNYLIDQKRYTSPTYLILDRMKMEKRTFLDLYCCLKKLKRSDIIDNCREELTRDAMEFLKKTGKFLFEHVNQEAFKQITSPTELDEAKKTIGKLFTTDIIETANRQIDIYDVFISFESESIDDIKIMWLISGRLESRGLTVAKGSYSFIQGVCINEAFANAIYNRSKKVILLISKAFINSESCLMQLNFARDADRASRRNKIIPVYIEEVKKPECIASINGFNYYNNSIREMFFDSFINSF Sbjct: 1 MNISDYFSSVPIHALSEKCKEKLKFLDCTFIIPDTEMKLRDYRGLAVLLNYSTLELNYLIDQKRYTSPTYLILDRMKMEKRTFLDLYCCLKKLKRSDIIDNCREELTRDAMEFLKKTGKFLFEHVNQEAFKQITSPTELDEAKKTIGKLFTTDIIETANRQIDIYDVFISFESESIDDIKIMWLISGRLESRGLTVAKGSYSFIQGVCINEAFANAIYNRSKKVILLISKAFINSESCLMQLNFARDADRASRRNKIIPVYIEEVKKPECIASINGFNYYNNSIREMFFDSFINSF 296 The following BLAST results are available for this feature:
BLAST of Myeloid differentiation primary response protein MyD88 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99) Total hits: 0
BLAST of Myeloid differentiation primary response protein MyD88 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99) Total hits: 0
BLAST of Myeloid differentiation primary response protein MyD88 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99) Total hits: 0
BLAST of Myeloid differentiation primary response protein MyD88 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99) Total hits: 1
BLAST of Myeloid differentiation primary response protein MyD88 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99) Total hits: 1
BLAST of Myeloid differentiation primary response protein MyD88 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99) Total hits: 0
BLAST of Myeloid differentiation primary response protein MyD88 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt) Total hits: 4
BLAST of Myeloid differentiation primary response protein MyD88 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL) Total hits: 5
BLAST of Myeloid differentiation primary response protein MyD88 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99) Total hits: 0
BLAST of Myeloid differentiation primary response protein MyD88 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99) Total hits: 0
BLAST of Myeloid differentiation primary response protein MyD88 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46) Total hits: 0
BLAST of Myeloid differentiation primary response protein MyD88 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46) Total hits: 1
BLAST of Myeloid differentiation primary response protein MyD88 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99) Total hits: 1
BLAST of Myeloid differentiation primary response protein MyD88 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST) Total hits: 1
Analyses
This transcript is derived from or has results from the following analyses Sequences
The following sequences are available for this feature:
transcript sequence >SMED30014235 ID=SMED30014235|Name=Myeloid differentiation primary response protein MyD88|organism=Schmidtea mediterranea sexual|type=transcript|length=1401bpback to top protein sequence of SMED30014235-orf-1 >SMED30014235-orf-1 ID=SMED30014235-orf-1|Name=SMED30014235-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=297bp MNISDYFSSVPIHALSEKCKEKLKFLDCTFIIPDTEVKLRDYRGLAVLLNback to top Annotated Terms
The following terms have been associated with this transcript:
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
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