GCR129

Overview
NameGCR129
Smed IDSMED30014227
Length (bp)1188
Neoblast Clusters

Zeng et. al., 2018



 

 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)



Explore this single cell expression dataset with our NB Cluster Shiny App



Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020



SMED30014227

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 1

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
testisSMED30014227SMESG000059005.1 GCR129smed_ncbi_20200123PMID:27163480
Saberi et al., 2016		whole organism adult hermaphrodite colorimetric in situ hybridization evidence
Note: Hover over icons to view figure legend
Homology
[Close]
BLAST of GCR129 vs. Ensembl Human
Match: ADRB2 (adrenoceptor beta 2 [Source:HGNC Symbol;Acc:HGNC:286])

HSP 1 Score: 80.4925 bits (197), Expect = 6.139e-16
Identity = 61/205 (29.76%), Postives = 100/205 (48.78%), Query Frame = 2 
Query:  218 VMLILVVASIIGNVAVIVKLITLGKDFRRNHLIFIFNYAIIEFLLASFVMGV-----NAAYVISNQWILGNFICSLSCSVNYFCIISSTVTFSLLIIDRYMAICHSLRYNTFVTKSKIQLQILFIWIIGILFSTVPV--------HQKAIITSYYELGCAVDWLAASSXXXXXXXXXXXXXXAIPLFVIMYCYYRIISKIKEISQ 793
            VM ++V+A + GNV VI  +      F R  L  + NY I     A  VMG+      AA+++   W  GNF C    S++  C+ +S  T  ++ +DRY AI    +Y + +TK+K ++ IL +WI+  L S +P+        HQ+AI     E  C  D+    ++ I     +F     +PL ++++ Y R+  + K   Q
Sbjct:   39 VMSLIVLAIVFGNVLVITAI----AKFER--LQTVTNYFITSLACADLVMGLAVVPFGAAHILMKMWTFGNFWCEFWTSIDVLCVTASIETLCVIAVDRYFAITSPFKYQSLLTKNKARVIILMVWIVSGLTSFLPIQMHWYRATHQEAINCYANETCC--DFFTNQAYAIASSIVSFY----VPLVIMVFVYSRVFQEAKRQLQ 231
[Close]
BLAST of GCR129 vs. Ensembl Human
Match: ADRA1B (adrenoceptor alpha 1B [Source:HGNC Symbol;Acc:HGNC:278])

HSP 1 Score: 70.4774 bits (171), Expect = 1.387e-12
Identity = 42/139 (30.22%), Postives = 77/139 (55.40%), Query Frame = 2 
Query:  200 RVIISGVML-ILVVASIIGNVAVIVKLITLGKDFRRNHLIFIFNYAIIEFLLASFVMGVNAAYVISNQWILGNFICSLSCSVNYFCIISSTVTFSLLIIDRYMAICHSLRYNTFVTKSKIQLQILFIWIIGILFSTVPV 613
            R I  G++L   ++ +I+GN+ VI+  +   +  R     FI N A+ + LL+  V+  +AA  +   W+LG   C +  +V+  C  +S ++   + IDRY+ + +SL+Y T VT+ K  L +L +W++  + S  P+
Sbjct:   44 RAISVGLVLGAFILFAIVGNILVILS-VACNRHLRTPTNYFIVNLAMADLLLSFTVLPFSAALEVLGYWVLGRIFCDIWAAVDVLCCTASILSLCAISIDRYIGVRYSLQYPTLVTRRKAILALLSVWVLSTVISIGPL 181
[Close]
BLAST of GCR129 vs. Ensembl Human
Match: ADRB1 (adrenoceptor beta 1 [Source:HGNC Symbol;Acc:HGNC:285])

HSP 1 Score: 68.1662 bits (165), Expect = 7.145e-12
Identity = 44/148 (29.73%), Postives = 80/148 (54.05%), Query Frame = 2 
Query:  176 VSMRTTAERVIISGVMLILVVASIIGNVAVIVKLITLGKDFRRNHL--IFIFNYAIIEFLLASFVMGVNAAYVISNQWILGNFICSLSCSVNYFCIISSTVTFSLLIIDRYMAICHSLRYNTFVTKSKIQLQILFIWIIGILFSTVPV 613
            +S + TA   ++  ++++L+VA   GNV VIV    + K  R   L  +FI + A  + ++   V+   A  V+  +W  G+F C L  SV+  C+ +S  T  ++ +DRY+AI    RY + +T+++ +  +  +W I  L S +P+
Sbjct:   53 LSQQWTAGMGLLMALIVLLIVA---GNVLVIV---AIAKTPRLQTLTNLFIMSLASADLVMGLLVVPFGATIVVWGRWEYGSFFCELWTSVDVLCVTASIETLCVIALDRYLAITSPFRYQSLLTRARARGLVCTVWAISALVSFLPI 194
[Close]
BLAST of GCR129 vs. Ensembl Human
Match: ADRB3 (adrenoceptor beta 3 [Source:HGNC Symbol;Acc:HGNC:288])

HSP 1 Score: 65.855 bits (159), Expect = 3.897e-11
Identity = 36/137 (26.28%), Postives = 67/137 (48.91%), Query Frame = 2 
Query:  242 SIIGNVAVIVKLITLGKDFRRNHLIFIFNYAIIEFLLASFVMGVNAAYVISNQWILGNFICSLSCSVNYFCIISSTVTFSLLIIDRYMAICHSLRYNTFVTKSKIQLQILFIWIIGILFSTVPVHQKAIITSYYELG 652
            ++ GN+ VIV  I      +    +F+ + A  + ++   V+   A   ++  W LG   C L  SV+  C+ +S  T   L +DRY+A+ + LRY   VTK   +  ++ +W++    S  P     I++ ++ +G
Sbjct:   51 TVGGNLLVIVA-IAWTPRLQTMTNVFVTSLAAADLVMGLLVVPPAATLALTGHWPLGATGCELWTSVDVLCVTASIETLCALAVDRYLAVTNPLRYGALVTKRCARTAVVLVWVVSAAVSFAP-----IMSQWWRVG 181
[Close]
BLAST of GCR129 vs. Ensembl Human
Match: ADRA1A (adrenoceptor alpha 1A [Source:HGNC Symbol;Acc:HGNC:277])

HSP 1 Score: 64.3142 bits (155), Expect = 7.028e-11
Identity = 51/230 (22.17%), Postives = 107/230 (46.52%), Query Frame = 2 
Query:  200 RVIISGVMLI-LVVASIIGNVAVIVKLITLGKDFRRNHLI---FIFNYAIIEFLLASFVMGVNAAYVISNQWILGNFICSLSCSVNYFCIISSTVTFSLLIIDRYMAICHSLRYNTFVTKSKIQLQILFIWIIGILFSTVPVHQKAIITSYYELGCAVDWLAASSXXXXXXXXXXXXXXAIPLFVIMYCYYRIISKIKEISQTFQSPNVIPSNTISERISSDQKVIRSHE 877
            + I+ GV+L  L++  ++GN+ VI+ +       R  H +   +I N A+ + LL S V+  +A + +   W  G   C++  +V+  C  +S +   ++ IDRY+ + + LRY T VT+ +  + +L +W + ++ S  P+          E  C ++         V  +     +  + + ++MYC   +++K        +    + S   +++  S+Q  +R H 
Sbjct:   25 KAILLGVILGGLILFGVLGNILVILSVAC----HRHLHSVTHYYIVNLAVADLLLTSTVLPFSAIFEVLGYWAFGRVFCNIWAAVDVLCCTASIMGLCIISIDRYIGVSYPLRYPTIVTQRRGLMALLCVWALSLVISIGPLFGWRQPAPEDETICQIN----EEPGYVLFSALGSFYLPLAIILVMYCRVYVVAK--------RESRGLKSGLKTDKSDSEQVTLRIHR 238
[Close]
BLAST of GCR129 vs. Ensembl Celegans
Match: ser-5 (SERotonin/octopamine receptor family [Source:UniProtKB/TrEMBL;Acc:G5EBX8])

HSP 1 Score: 72.0182 bits (175), Expect = 1.606e-13
Identity = 43/134 (32.09%), Postives = 74/134 (55.22%), Query Frame = 2 
Query:  224 LILVVASIIGNVAVIVKLITLGKDFRRNHLIFIFNYAIIEFLLASFVMGVNAAYVISNQWILGNFICSLSCSVNYFCIISSTVTFSLLIIDRYMAICHSLRYNTFVTKSKIQLQILFIWII--GILFSTVPVHQ 619
            +I+++ +I GN+ V+     +G   R N  + ++N  + +FL+   V+ + A Y+I  +WI G F+C L  + +      S VT  ++ +DRY+A+   LRY + VTK+K+   +  IWI    IL +TV   Q
Sbjct:   70 VIIILLTIFGNLLVLFFKARVG---RTNTTLLVWNLGLTDFLVGVIVLPMGAVYLIYRKWIFGRFLCRLWVAADVTFCTCSVVTICVISVDRYLAVTRPLRYKSIVTKTKVISVMTIIWIFSSSILLTTVRWEQ 200
[Close]
BLAST of GCR129 vs. Ensembl Celegans
Match: gar-2 (Muscarinic acetylcholine receptor gar-2 [Source:UniProtKB/Swiss-Prot;Acc:Q09388])

HSP 1 Score: 68.9366 bits (167), Expect = 4.394e-13
Identity = 45/135 (33.33%), Postives = 79/135 (58.52%), Query Frame = 2 
Query:  203 VIISGVMLILVVASIIGNVAVIVKLITLGKDFRRNHLIFIFNYAIIEFLLASFVMGVNAA-YVISNQWILGNFICSLSCSVNYFCIISSTVTFSLLIIDRYMAICHSLRYNTFVTKSKIQLQILFIWII-GILFS 601
            V+++  ML L + ++IGN+AV++    L K+ R+    FIF+ AI + L+    + V  A Y+ +N+WI G+ +C L  S++Y   ++S  T   + +DRY ++     Y  + T  ++ L I+FIW++  ILFS
Sbjct:    6 VLLALFMLFLSIVTVIGNLAVLLSYY-LDKNIRQPTNYFIFSLAISDLLIGLEGIPVYTAFYLNNNEWIWGDVLCDLWLSIDYIVCLASIYTVLGITVDRYYSVKKPATYRNWRTPGRVVLIIIFIWLVPSILFS 139
[Close]
BLAST of GCR129 vs. Ensembl Celegans
Match: gar-2 (Muscarinic acetylcholine receptor gar-2 [Source:UniProtKB/Swiss-Prot;Acc:Q09388])

HSP 1 Score: 68.5514 bits (166), Expect = 2.517e-12
Identity = 45/135 (33.33%), Postives = 79/135 (58.52%), Query Frame = 2 
Query:  203 VIISGVMLILVVASIIGNVAVIVKLITLGKDFRRNHLIFIFNYAIIEFLLASFVMGVNAA-YVISNQWILGNFICSLSCSVNYFCIISSTVTFSLLIIDRYMAICHSLRYNTFVTKSKIQLQILFIWII-GILFS 601
            V+++  ML L + ++IGN+AV++    L K+ R+    FIF+ AI + L+    + V  A Y+ +N+WI G+ +C L  S++Y   ++S  T   + +DRY ++     Y  + T  ++ L I+FIW++  ILFS
Sbjct:    6 VLLALFMLFLSIVTVIGNLAVLLSYY-LDKNIRQPTNYFIFSLAISDLLIGLEGIPVYTAFYLNNNEWIWGDVLCDLWLSIDYIVCLASIYTVLGITVDRYYSVKKPATYRNWRTPGRVVLIIIFIWLVPSILFS 139
[Close]
BLAST of GCR129 vs. Ensembl Celegans
Match: gar-2 (Muscarinic acetylcholine receptor gar-2 [Source:UniProtKB/Swiss-Prot;Acc:Q09388])

HSP 1 Score: 68.5514 bits (166), Expect = 2.940e-12
Identity = 45/135 (33.33%), Postives = 79/135 (58.52%), Query Frame = 2 
Query:  203 VIISGVMLILVVASIIGNVAVIVKLITLGKDFRRNHLIFIFNYAIIEFLLASFVMGVNAA-YVISNQWILGNFICSLSCSVNYFCIISSTVTFSLLIIDRYMAICHSLRYNTFVTKSKIQLQILFIWII-GILFS 601
            V+++  ML L + ++IGN+AV++    L K+ R+    FIF+ AI + L+    + V  A Y+ +N+WI G+ +C L  S++Y   ++S  T   + +DRY ++     Y  + T  ++ L I+FIW++  ILFS
Sbjct:    6 VLLALFMLFLSIVTVIGNLAVLLSYY-LDKNIRQPTNYFIFSLAISDLLIGLEGIPVYTAFYLNNNEWIWGDVLCDLWLSIDYIVCLASIYTVLGITVDRYYSVKKPATYRNWRTPGRVVLIIIFIWLVPSILFS 139
[Close]
BLAST of GCR129 vs. Ensembl Celegans
Match: gar-2 (Muscarinic acetylcholine receptor gar-2 [Source:UniProtKB/Swiss-Prot;Acc:Q09388])

HSP 1 Score: 68.5514 bits (166), Expect = 3.213e-12
Identity = 45/135 (33.33%), Postives = 79/135 (58.52%), Query Frame = 2 
Query:  203 VIISGVMLILVVASIIGNVAVIVKLITLGKDFRRNHLIFIFNYAIIEFLLASFVMGVNAA-YVISNQWILGNFICSLSCSVNYFCIISSTVTFSLLIIDRYMAICHSLRYNTFVTKSKIQLQILFIWII-GILFS 601
            V+++  ML L + ++IGN+AV++    L K+ R+    FIF+ AI + L+    + V  A Y+ +N+WI G+ +C L  S++Y   ++S  T   + +DRY ++     Y  + T  ++ L I+FIW++  ILFS
Sbjct:    6 VLLALFMLFLSIVTVIGNLAVLLSYY-LDKNIRQPTNYFIFSLAISDLLIGLEGIPVYTAFYLNNNEWIWGDVLCDLWLSIDYIVCLASIYTVLGITVDRYYSVKKPATYRNWRTPGRVVLIIIFIWLVPSILFS 139
[Close]
BLAST of GCR129 vs. Ensembl Fly
Match: Oct-TyrR (gene:FBgn0004514 transcript:FBtr0078479)

HSP 1 Score: 65.0846 bits (157), Expect = 3.905e-11
Identity = 41/139 (29.50%), Postives = 73/139 (52.52%), Query Frame = 2 
Query:  197 ERVIISGVMLILVVASIIGNVAVIVKLITLGKDFRRNHLIFIFNYAIIEFLLASFVMGVNAAYVISNQWILGNFICSLSCSVNYFCIISSTVTFSLLIIDRYMAICHSLRYNTFVTKSKIQLQILFIWIIGILFSTVPV 613
            E ++ + V+ +++V +IIGN+ VI+ + T  K  R     FI + A+ +  +A  V+  N AY I  +W  G  +C L  + +  C  SS +    + +DRY AI   + Y    T  ++ L I  +W++ +L S+ P+
Sbjct:  108 EALLTALVLSVIIVLTIIGNILVILSVFTY-KPLRIVQNFFIVSLAVADLTVALLVLPFNVAYSILGRWEFGIHLCKLWLTCDVLCCTSSILNLCAIALDRYWAITDPINYAQKRTVGRVLLLISGVWLLSLLISSPPL 245
[Close]
BLAST of GCR129 vs. Ensembl Fly
Match: Oct-TyrR (gene:FBgn0004514 transcript:FBtr0301930)

HSP 1 Score: 65.0846 bits (157), Expect = 3.905e-11
Identity = 41/139 (29.50%), Postives = 73/139 (52.52%), Query Frame = 2 
Query:  197 ERVIISGVMLILVVASIIGNVAVIVKLITLGKDFRRNHLIFIFNYAIIEFLLASFVMGVNAAYVISNQWILGNFICSLSCSVNYFCIISSTVTFSLLIIDRYMAICHSLRYNTFVTKSKIQLQILFIWIIGILFSTVPV 613
            E ++ + V+ +++V +IIGN+ VI+ + T  K  R     FI + A+ +  +A  V+  N AY I  +W  G  +C L  + +  C  SS +    + +DRY AI   + Y    T  ++ L I  +W++ +L S+ P+
Sbjct:  108 EALLTALVLSVIIVLTIIGNILVILSVFTY-KPLRIVQNFFIVSLAVADLTVALLVLPFNVAYSILGRWEFGIHLCKLWLTCDVLCCTSSILNLCAIALDRYWAITDPINYAQKRTVGRVLLLISGVWLLSLLISSPPL 245
[Close]
BLAST of GCR129 vs. Ensembl Fly
Match: 5-HT1B (gene:FBgn0263116 transcript:FBtr0330055)

HSP 1 Score: 63.929 bits (154), Expect = 9.592e-11
Identity = 58/225 (25.78%), Postives = 104/225 (46.22%), Query Frame = 2 
Query:  218 VMLILVVASIIGNVAVIVKLITLGKDFRRNHLIFIFNYAIIEFLLASFVMGVNAAYVISNQWILGNFICSLSCSVNYFCIISSTVTFSLLIIDRYMAICHSLRYNTFVTKSKIQLQILFIWIIGILFSTVPV---HQKAIITSYYELGCAVDWLAASSXXXXXXXXXXXXXXAIPLFVIMYCYYR--IISKIKEISQTFQSPNVIPSNTISERISSDQKVIRSHE 877
            V+ ++++ +IIGNV VI  +I L ++ +      + + A+ +  +A  VM + A Y ISN WILG  +C +  S +  C  +S +    +  DRY  + + + YN   T  ++ L I  +W   ++ S  P         +    E  C V      S  + +  F     F +PL VI++ Y++  II++ +   +  +S NV  + T  +    + K  RS  
Sbjct:   96 VLGLMILVTIIGNVFVIAAII-LERNLQNVANYLVASLAVADLFVACLVMPLGAVYEISNGWILGPELCDIWTSCDVLCCTASILHLVAIAADRYWTVTN-IDYNNLRTPRRVFLMIFCVWFAALIVSLAPQFGWKDPDYMKRIEEQHCMV------SQDVGYQIFATCCTFYVPLLVILFLYWKIYIIARKRIQRRAQKSFNVTLTETDCDSAVRELKKERSKR 312
[Close]
BLAST of GCR129 vs. Ensembl Fly
Match: 5-HT1B (gene:FBgn0263116 transcript:FBtr0086599)

HSP 1 Score: 63.1586 bits (152), Expect = 1.775e-10
Identity = 58/225 (25.78%), Postives = 104/225 (46.22%), Query Frame = 2 
Query:  218 VMLILVVASIIGNVAVIVKLITLGKDFRRNHLIFIFNYAIIEFLLASFVMGVNAAYVISNQWILGNFICSLSCSVNYFCIISSTVTFSLLIIDRYMAICHSLRYNTFVTKSKIQLQILFIWIIGILFSTVPV---HQKAIITSYYELGCAVDWLAASSXXXXXXXXXXXXXXAIPLFVIMYCYYR--IISKIKEISQTFQSPNVIPSNTISERISSDQKVIRSHE 877
            V+ ++++ +IIGNV VI  +I L ++ +      + + A+ +  +A  VM + A Y ISN WILG  +C +  S +  C  +S +    +  DRY  + + + YN   T  ++ L I  +W   ++ S  P         +    E  C V      S  + +  F     F +PL VI++ Y++  II++ +   +  +S NV  + T  +    + K  RS  
Sbjct:   96 VLGLMILVTIIGNVFVIAAII-LERNLQNVANYLVASLAVADLFVACLVMPLGAVYEISNGWILGPELCDIWTSCDVLCCTASILHLVAIAADRYWTVTN-IDYNNLRTPRRVFLMIFCVWFAALIVSLAPQFGWKDPDYMKRIEEQHCMV------SQDVGYQIFATCCTFYVPLLVILFLYWKIYIIARKRIQRRAQKSFNVTLTETDCDSAVRELKKERSKR 312
[Close]
BLAST of GCR129 vs. Ensembl Fly
Match: 5-HT1B (gene:FBgn0263116 transcript:FBtr0330056)

HSP 1 Score: 63.1586 bits (152), Expect = 2.049e-10
Identity = 58/225 (25.78%), Postives = 104/225 (46.22%), Query Frame = 2 
Query:  218 VMLILVVASIIGNVAVIVKLITLGKDFRRNHLIFIFNYAIIEFLLASFVMGVNAAYVISNQWILGNFICSLSCSVNYFCIISSTVTFSLLIIDRYMAICHSLRYNTFVTKSKIQLQILFIWIIGILFSTVPV---HQKAIITSYYELGCAVDWLAASSXXXXXXXXXXXXXXAIPLFVIMYCYYR--IISKIKEISQTFQSPNVIPSNTISERISSDQKVIRSHE 877
            V+ ++++ +IIGNV VI  +I L ++ +      + + A+ +  +A  VM + A Y ISN WILG  +C +  S +  C  +S +    +  DRY  + + + YN   T  ++ L I  +W   ++ S  P         +    E  C V      S  + +  F     F +PL VI++ Y++  II++ +   +  +S NV  + T  +    + K  RS  
Sbjct:   96 VLGLMILVTIIGNVFVIAAII-LERNLQNVANYLVASLAVADLFVACLVMPLGAVYEISNGWILGPELCDIWTSCDVLCCTASILHLVAIAADRYWTVTN-IDYNNLRTPRRVFLMIFCVWFAALIVSLAPQFGWKDPDYMKRIEEQHCMV------SQDVGYQIFATCCTFYVPLLVILFLYWKIYIIARKRIQRRAQKSFNVTLTETDCDSAVRELKKERSKR 312
[Close]
BLAST of GCR129 vs. Ensembl Zebrafish
Match: adrb2a (adrenoceptor beta 2, surface a [Source:ZFIN;Acc:ZDB-GENE-100414-3])

HSP 1 Score: 86.6557 bits (213), Expect = 3.270e-18
Identity = 63/249 (25.30%), Postives = 125/249 (50.20%), Query Frame = 2 
Query:  176 VSMRTTAERVIISGVMLILVVASIIGNVAVIVKLITLGKDFRRNHLIFIFNYAIIEFLLASFVMGV-----NAAYVISNQWILGNFICSLSCSVNYFCIISSTVTFSLLIIDRYMAICHSLRYNTFVTKSKIQLQILFIWIIGILFSTVPVHQKAIITSYYELGCAVD--WLAASSXXXXXXXXXXXXXXAIPLFVIMYCYYRII----SKIKEISQTFQSPNVIPSNTISERISSDQKVIRSHEILLF 889
             S ++  +  ++  +M ILV+  + GNV VI  +      F+R  L  + N  I     A  VMG+      A Y+I N W  G+F+C    + +  C+ +S  T  ++ +DRY+AI    RY + +TK++ +  +L +W+I  L S +P+H +  I++  E  C  +  +         +   + ++ F IPL ++++ Y R+      ++K+I++T    +   SN+ ++ ++++   +RS +   F
Sbjct:   20 ASTKSELQMTVLGTLMSILVLIIVFGNVMVITAI----SRFQR--LQNVTNCFITSLACADLVMGLVVIPFGALYIILNTWHFGHFLCDFWTATDVLCVTASIETLCVIAMDRYIAITSPFRYQSLLTKNRARFIVLMVWVIAGLVSYLPIHMEWWISTDNETLCCYNNTYCCEFDITYSYAIVSSIISFYIPLVIMVFVYSRVFQEARKQLKKINKTEGRFHAQKSNSRNQDVANNHSEMRSTKKAKF 262
[Close]
BLAST of GCR129 vs. Ensembl Zebrafish
Match: adrb2b (adrenoceptor beta 2, surface b [Source:ZFIN;Acc:ZDB-GENE-070410-32])

HSP 1 Score: 82.8037 bits (203), Expect = 6.809e-17
Identity = 83/326 (25.46%), Postives = 141/326 (43.25%), Query Frame = 2 
Query:  176 VSMRTTAERVIISGVMLILVVASIIGNVAVIVKLITLGKDFRRNHLIFIFNYAIIEFLLASFVMGV-----NAAYVISNQWILGNFICSLSCSVNYFCIISSTVTFSLLIIDRYMAICHSLRYNTFVTKSKIQLQILFIWIIGILFSTVPVHQKAIITSYYE-LGCAVDWLAAS-SXXXXXXXXXXXXXXAIPLFVIMYCYYRIISKIKEISQTF---------QSPNVIPSNTISERIS----SDQKVIRSHEILLFAIVMSIGPYW----ISKILKMSQDQEFGP----NYLTTAGSLVPLIGSLITPLIYVNMQTEICVVTEV 1069
            VS  + AE V+IS ++ ILV+  + GN  VI  ++      R   L  + NY I     A  VMG+      A Y++ N W  GNF C    + +  C+ +S  T  ++ +DRY+AI   LRY + +TK K    ++ +W +  L S +P+H +  ++   E L C  +      +    +   + ++ F IPL ++ + Y R+  + +   Q           QS +    N I  R +     D K +++  I++    +   P++    ++ I KM  D    P    N++  A        S   PLIY       C   E+
Sbjct:   32 VSEYSDAEVVLISILIGILVLVIVFGNALVISAIV------RFQRLQTVTNYFISSLACADLVMGLMVVPFGACYILLNTWHFGNFFCEFWTATDVLCVTASIETLCVIALDRYIAIMWPLRYQSMLTKRKACGMVIGVWAVAALISFLPIHMEWWVSDEPEALSCLEEPTCCDFNTNAAYAVTSSIISFYIPLVIMAFVYSRVFQEARRQLQKIDRIEGRIRTQSLSTQEGNEIKNRRTKFCMKDHKALKTLGIIMGTFTLCWLPFFVLNVVAAIWKM--DNIMLPFRILNWIGYA-------NSAFNPLIYCRSPEFRCAFQEI 342
[Close]
BLAST of GCR129 vs. Ensembl Zebrafish
Match: adrb2b (adrenoceptor beta 2, surface b [Source:ZFIN;Acc:ZDB-GENE-070410-32])

HSP 1 Score: 82.8037 bits (203), Expect = 7.132e-17
Identity = 83/326 (25.46%), Postives = 141/326 (43.25%), Query Frame = 2 
Query:  176 VSMRTTAERVIISGVMLILVVASIIGNVAVIVKLITLGKDFRRNHLIFIFNYAIIEFLLASFVMGV-----NAAYVISNQWILGNFICSLSCSVNYFCIISSTVTFSLLIIDRYMAICHSLRYNTFVTKSKIQLQILFIWIIGILFSTVPVHQKAIITSYYE-LGCAVDWLAAS-SXXXXXXXXXXXXXXAIPLFVIMYCYYRIISKIKEISQTF---------QSPNVIPSNTISERIS----SDQKVIRSHEILLFAIVMSIGPYW----ISKILKMSQDQEFGP----NYLTTAGSLVPLIGSLITPLIYVNMQTEICVVTEV 1069
            VS  + AE V+IS ++ ILV+  + GN  VI  ++      R   L  + NY I     A  VMG+      A Y++ N W  GNF C    + +  C+ +S  T  ++ +DRY+AI   LRY + +TK K    ++ +W +  L S +P+H +  ++   E L C  +      +    +   + ++ F IPL ++ + Y R+  + +   Q           QS +    N I  R +     D K +++  I++    +   P++    ++ I KM  D    P    N++  A        S   PLIY       C   E+
Sbjct:   32 VSEYSDAEVVLISILIGILVLVIVFGNALVISAIV------RFQRLQTVTNYFISSLACADLVMGLMVVPFGACYILLNTWHFGNFFCEFWTATDVLCVTASIETLCVIALDRYIAIMWPLRYQSMLTKRKACGMVIGVWAVAALISFLPIHMEWWVSDEPEALSCLEEPTCCDFNTNAAYAVTSSIISFYIPLVIMAFVYSRVFQEARRQLQKIDRIEGRIRTQSLSTQEGNEIKNRRTKFCMKDHKALKTLGIIMGTFTLCWLPFFVLNVVAAIWKM--DNIMLPFRILNWIGYA-------NSAFNPLIYCRSPEFRCAFQEI 342
[Close]
BLAST of GCR129 vs. Ensembl Zebrafish
Match: adrb1 (adrenoceptor beta 1 [Source:ZFIN;Acc:ZDB-GENE-081022-145])

HSP 1 Score: 75.485 bits (184), Expect = 1.781e-14
Identity = 66/274 (24.09%), Postives = 135/274 (49.27%), Query Frame = 2 
Query:  176 VSMRTTAERVIISGVMLILVVASII-GNVAVIVKLITLGKDFRRNHL--IFIFNYAIIEFLLASFVMGVNAAYVISNQWILGNFICSLSCSVNYFCIISSTVTFSLLIIDRYMAICHSLRYNTFVTKSKIQLQILFIWIIGILFSTVPV----HQKAIITSYYELGCAVDWLAASSXXXXXXXXXXXXXXAIPLFVIMYCYYRI-------ISKIKEISQTF---QSPNVIPSNTISERISS--DQKVIRSHEILLFAIVMSIGPYWISKILKM 940
            V +  + + ++  G+++ L+V  I+ GN+ VIV    + ++ R   L  +FI + A  + ++   V+   AA  +   W+ G+F C    S++  C+ +S  T  ++ IDRY+AI    RY + +TK++ ++ +  +W I  L S  P+     Q +  TS YE     D++   ++ I     +F     IPL V+++ Y R+       ++KI +    F      N  P+   + +I +  +QK +++  I++    +   P++I  ++++
Sbjct:   19 VDLNVSEQWLVGMGILMGLIVFVIVVGNILVIV---AIARNQRLQTLTNVFIVSLACADLIMGLLVVPFGAALEVRGAWMYGSFFCEFWISLDVLCVTASIETLCVIAIDRYIAIISPFRYQSLLTKARAKVVVCAVWAISALVSFPPILMHWSQDSEETSCYENPECCDFVTNRAYAISSSIISFY----IPLIVMIFVYARVYREAKQQLNKINKCEGRFYNNHGTNCKPTRKRTTKILALKEQKALKTLGIIMGTFTLCWLPFFIVNVVRV 285
[Close]
BLAST of GCR129 vs. Ensembl Zebrafish
Match: adrb1 (adrenoceptor beta 1 [Source:ZFIN;Acc:ZDB-GENE-081022-145])

HSP 1 Score: 75.485 bits (184), Expect = 1.781e-14
Identity = 66/274 (24.09%), Postives = 135/274 (49.27%), Query Frame = 2 
Query:  176 VSMRTTAERVIISGVMLILVVASII-GNVAVIVKLITLGKDFRRNHL--IFIFNYAIIEFLLASFVMGVNAAYVISNQWILGNFICSLSCSVNYFCIISSTVTFSLLIIDRYMAICHSLRYNTFVTKSKIQLQILFIWIIGILFSTVPV----HQKAIITSYYELGCAVDWLAASSXXXXXXXXXXXXXXAIPLFVIMYCYYRI-------ISKIKEISQTF---QSPNVIPSNTISERISS--DQKVIRSHEILLFAIVMSIGPYWISKILKM 940
            V +  + + ++  G+++ L+V  I+ GN+ VIV    + ++ R   L  +FI + A  + ++   V+   AA  +   W+ G+F C    S++  C+ +S  T  ++ IDRY+AI    RY + +TK++ ++ +  +W I  L S  P+     Q +  TS YE     D++   ++ I     +F     IPL V+++ Y R+       ++KI +    F      N  P+   + +I +  +QK +++  I++    +   P++I  ++++
Sbjct:   19 VDLNVSEQWLVGMGILMGLIVFVIVVGNILVIV---AIARNQRLQTLTNVFIVSLACADLIMGLLVVPFGAALEVRGAWMYGSFFCEFWISLDVLCVTASIETLCVIAIDRYIAIISPFRYQSLLTKARAKVVVCAVWAISALVSFPPILMHWSQDSEETSCYENPECCDFVTNRAYAISSSIISFY----IPLIVMIFVYARVYREAKQQLNKINKCEGRFYNNHGTNCKPTRKRTTKILALKEQKALKTLGIIMGTFTLCWLPFFIVNVVRV 285
[Close]
BLAST of GCR129 vs. Ensembl Xenopus
Match: ENSXETT00000011711.1 (adrenoceptor alpha 1B [Source:NCBI gene;Acc:100488806])

HSP 1 Score: 79.337 bits (194), Expect = 1.782e-15
Identity = 62/226 (27.43%), Postives = 109/226 (48.23%), Query Frame = 2 
Query:  200 RVIISGVML-ILVVASIIGNVAVIVKLITLGKDFRRNHLIFIFNYAIIEFLLASFVMGVNAAYVISNQWILGNFICSLSCSVNYFCIISSTVTFSLLIIDRYMAICHSLRYNTFVTKSKIQLQILFIWIIGILFSTVPVHQKAIITSYYELGCAVDWLAASSXXXXXXXXXXXXXXAIPLFVIMYCYYRIISKIKEISQTFQSPNVIPSNTISERISSDQKVIRSH 874
            R ++ G  L   +  +IIGN+ VI+ ++T  K  R      I N AI + LL+S V+  +A   I   W+ G  +C +  +++  C  +S  +   + IDRY+ + HSLRY T VT+ +  L +L +W+   + S  P      +  + E      ++   +  I +  F+ +  F IPL VI+  Y R+    K I++  +      +  + ER+ S +  +R H
Sbjct:   43 RAMLLGFTLGAFISVAIIGNIMVIISVVT-NKQLRIPTNYLIVNLAIADLLLSSTVLPFSATKEIVGYWVFGRILCDVWAAMDVLCCTASIFSLCTISIDRYIGVRHSLRYPTIVTRKRTILALLGVWMFSTVISIGP------LLGWKEPAPPDTYVCEITTEIFYAIFSSLASFYIPLIVILVMYCRVYVVAKRITKNLE------AGVMKERMDSKELTLRIH 255
[Close]
BLAST of GCR129 vs. Ensembl Xenopus
Match: prrc2c (proline-rich coiled-coil 2C [Source:Xenbase;Acc:XB-GENE-984671])

HSP 1 Score: 74.3294 bits (181), Expect = 5.838e-14
Identity = 70/297 (23.57%), Postives = 138/297 (46.46%), Query Frame = 2 
Query:  218 VMLILVVASIIGNVAVIVKLITLGKDFRRNHLIFIFNYAIIEFLLASFVMGV-----NAAYVISNQWILGNFICSLSCSVNYFCIISSTVTFSLLIIDRYMAICHSLRYNTFVTKSKIQLQILFIWIIGILFSTVPVH-------QKAIITSYYELGCAVDWLAASSXXXXXXXXXXXXXXAIPLFVIMYCYYRI-------ISKIKEISQTFQSPN---VIPSNTISERIS----SDQKVIRSHEILLFAIVMSIGPYWISKILKMSQDQEFGPNYLTTAGSLVPLIGSLITPLIY 1030
            +M  +V+  ++GNV VI  +      F+R  L  + NY I     A  +MG+      A+ +I + W+  NF C    SV+  C+ +S  T  ++ +DRY AI    RY + +TK K ++ IL +W++  L S +P++       +++ +  Y +  C   +   +     +   + ++ F +PL V+++ Y R+       + KI +    F + N          ++R S     + K +++  I++    +   P++I  I+++   ++F P  +    + V  + S   PLIY
Sbjct:   43 IMSCIVLVIVLGNVLVITAI----AKFQR--LQTVTNYFITSLACADLLMGLIVVPFGASSIILDTWVFNNFWCEFWTSVDILCVTASIETLCVIAVDRYFAITSPFRYQSLLTKCKARIVILLVWVVSTLTSFLPIYMHWYRIEEESALHCYDDPSCCFFFTNPA-----YAISSSIISFYLPLVVMIFVYARVFQEAKKQLKKIDKSEGRFHNQNNQQDTNGKQGNKRTSKFWLKEHKALKTLGIIMGTFTLCWLPFFIVNIVQVMH-KDFIPVKVYNFLNWVGYVNSAFNPLIY 327
[Close]
BLAST of GCR129 vs. Ensembl Xenopus
Match: ENSXETT00000006856.1 (pep primary_assembly:Xenopus_tropicalis_v9.1:3:118467762:118507139:-1 gene:ENSXETG00000012361.1 transcript:ENSXETT00000006856.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 69.707 bits (169), Expect = 2.132e-12
Identity = 38/145 (26.21%), Postives = 75/145 (51.72%), Query Frame = 2 
Query:  194 AERVIISGVMLILVVASIIGNVAVIVKLITLGKDFRRNHL--IFIFNYAIIEFLLASFVMGVNAAYVISNQWILGNFICSLSCSVNYFCIISSTVTFSLLIIDRYMAICHSLRYNTFVTKSKIQLQILFIWIIGILFSTVPVHQK 622
             +R ++  V+  +++  + GN+ VI   I + K  R   +  +FI + A  + ++   V+   A  +++  W+    +C L  SV+  C+ +S  T  ++ +DRY+AI   L+Y   VTK + +L +  +W I  L S +P+  +
Sbjct:   27 TQRWMLGAVLSFMIMVIVFGNMLVI---IAIAKTPRLQTMTNVFITSLACADLIMGLLVVPPGATILVTGDWLFETTVCELWTSVDVLCVTASIETLCVIAVDRYIAITSPLKYEMLVTKVRARLTVCLVWAISALISFLPIMNR 168
[Close]
BLAST of GCR129 vs. Ensembl Xenopus
Match: ENSXETT00000006865.1 (pep primary_assembly:Xenopus_tropicalis_v9.1:3:118467762:118507139:-1 gene:ENSXETG00000012361.1 transcript:ENSXETT00000006865.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 69.3218 bits (168), Expect = 2.506e-12
Identity = 39/153 (25.49%), Postives = 78/153 (50.98%), Query Frame = 2 
Query:  194 AERVIISGVMLILVVASIIGNVAVIVKLITLGKDFRRNHL--IFIFNYAIIEFLLASFVMGVNAAYVISNQWILGNFICSLSCSVNYFCIISSTVTFSLLIIDRYMAICHSLRYNTFVTKSKIQLQILFIWIIGILFSTVPVHQKAIITSYYE 646
             +R ++  V+  +++  + GN+ VI   I + K  R   +  +FI + A  + ++   V+   A  +++  W+    +C L  SV+  C+ +S  T  ++ +DRY+AI   L+Y   VTK + +L +  +W I  L S +P+  +    ++ E
Sbjct:   27 TQRWMLGAVLSFMIMVIVFGNMLVI---IAIAKTPRLQTMTNVFITSLACADLIMGLLVVPPGATILVTGDWLFETTVCELWTSVDVLCVTASIETLCVIAVDRYIAITSPLKYEMLVTKVRARLTVCLVWAISALISFLPIMNRWWRDTHNE 176
[Close]
BLAST of GCR129 vs. Ensembl Xenopus
Match: efr3b (EFR3 homolog B [Source:Xenbase;Acc:XB-GENE-6033491])

HSP 1 Score: 67.781 bits (164), Expect = 9.488e-12
Identity = 37/139 (26.62%), Postives = 76/139 (54.68%), Query Frame = 2 
Query:  200 RVIISGVML-ILVVASIIGNVAVIVKLITLGKDFRRNHLIFIFNYAIIEFLLASFVMGVNAAYVISNQWILGNFICSLSCSVNYFCIISSTVTFSLLIIDRYMAICHSLRYNTFVTKSKIQLQILFIWIIGILFSTVPV 613
            + I+ GV+  + +   ++GN+ VI+  +   +  +     FI N A+ + LL S V+  +A + I   W+ G   C++  +V+  C  +S ++   + IDRY+ + + LRY + +T+ +  L +L IW++ ++ S  P+
Sbjct:   49 KAIVVGVIFGVFITFGVLGNILVILS-VACHRHLQTVTHYFIANLAVADLLLMSMVLPFSATFEIQGYWLFGRIFCNIWAAVDVLCCTASIMSLCAISIDRYIGVSYPLRYPSIMTEKRGVLALLCIWVLSLVISIGPL 186
[Close]
BLAST of GCR129 vs. Ensembl Mouse
Match: Adrb2 (adrenergic receptor, beta 2 [Source:MGI Symbol;Acc:MGI:87938])

HSP 1 Score: 80.4925 bits (197), Expect = 4.089e-16
Identity = 71/254 (27.95%), Postives = 122/254 (48.03%), Query Frame = 2 
Query:  185 RTTAERVIISGVMLILVVASIIGNVAVIVKLITLGKDFRRNHLIFIFNYAIIEFLLASFVMGV-----NAAYVISNQWILGNFICSLSCSVNYFCIISSTVTFSLLIIDRYMAICHSLRYNTFVTKSKIQLQILFIWIIGILFSTVPV--------HQKAIITSYYELGCAVDWLAASSXXXXXXXXXXXXXXAIPLFVIMYCYYRI-------ISKIKEISQTFQSPNVIPSNTISERISSDQKVIRSHEILL 886
            R  A  V ++ +M ++V+A + GNV VI  +      F R  L  + NY II    A  VMG+      A++++   W  GNF C    S++  C+ +S  T  ++ +DRY+AI    +Y + +TK+K ++ IL +WI+  L S +P+        H+KA I  Y E  C  D+    ++ I     +F     +PL V+++ Y R+       + KI +    F + N+   + + +   S   + RS +  L
Sbjct:   28 RDEAWVVGMAILMSVIVLAIVFGNVLVITAI----AKFER--LQTVTNYFIISLACADLVMGLAVVPFGASHILMKMWNFGNFWCEFWTSIDVLCVTASIETLCVIAVDRYVAITSPFKYQSLLTKNKARVVILMVWIVSGLTSFLPIQMHWYRATHKKA-IDCYTEETCC-DFFTNQAYAIASSIVSFY----VPLVVMVFVYSRVFQVAKRQLQKIDKSEGRFHAQNL---SQVEQDGRSGHGLRRSSKFCL 266
[Close]
BLAST of GCR129 vs. Ensembl Mouse
Match: Adrb3 (adrenergic receptor, beta 3 [Source:MGI Symbol;Acc:MGI:87939])

HSP 1 Score: 72.7886 bits (177), Expect = 1.240e-13
Identity = 33/117 (28.21%), Postives = 60/117 (51.28%), Query Frame = 2 
Query:  314 IFIFNYAIIEFLLASFVMGVNAAYVISNQWILGNFICSLSCSVNYFCIISSTVTFSLLIIDRYMAICHSLRYNTFVTKSKIQLQILFIWIIGILFSTVPVHQKAIITSYYELGCAVD 664
            +F+ + A  + ++   VM   A   ++  W LG   C L  SV+  C+ +S  T   L +DRY+A+ + LRY T VTK + +  ++ +WI+    S  P     I++ ++ +G   +
Sbjct:   71 VFVTSLAAADLVVGLLVMPPGATLALTGHWPLGETGCELWTSVDVLCVTASIETLCALAVDRYLAVTNPLRYGTLVTKRRARAAVVLVWIVSAAVSFAP-----IMSQWWRVGADAE 182
[Close]
BLAST of GCR129 vs. Ensembl Mouse
Match: Adrb3 (adrenergic receptor, beta 3 [Source:MGI Symbol;Acc:MGI:87939])

HSP 1 Score: 72.7886 bits (177), Expect = 1.240e-13
Identity = 33/117 (28.21%), Postives = 60/117 (51.28%), Query Frame = 2 
Query:  314 IFIFNYAIIEFLLASFVMGVNAAYVISNQWILGNFICSLSCSVNYFCIISSTVTFSLLIIDRYMAICHSLRYNTFVTKSKIQLQILFIWIIGILFSTVPVHQKAIITSYYELGCAVD 664
            +F+ + A  + ++   VM   A   ++  W LG   C L  SV+  C+ +S  T   L +DRY+A+ + LRY T VTK + +  ++ +WI+    S  P     I++ ++ +G   +
Sbjct:   71 VFVTSLAAADLVVGLLVMPPGATLALTGHWPLGETGCELWTSVDVLCVTASIETLCALAVDRYLAVTNPLRYGTLVTKRRARAAVVLVWIVSAAVSFAP-----IMSQWWRVGADAE 182
[Close]
BLAST of GCR129 vs. Ensembl Mouse
Match: Adrb3 (adrenergic receptor, beta 3 [Source:MGI Symbol;Acc:MGI:87939])

HSP 1 Score: 72.7886 bits (177), Expect = 1.296e-13
Identity = 33/117 (28.21%), Postives = 60/117 (51.28%), Query Frame = 2 
Query:  314 IFIFNYAIIEFLLASFVMGVNAAYVISNQWILGNFICSLSCSVNYFCIISSTVTFSLLIIDRYMAICHSLRYNTFVTKSKIQLQILFIWIIGILFSTVPVHQKAIITSYYELGCAVD 664
            +F+ + A  + ++   VM   A   ++  W LG   C L  SV+  C+ +S  T   L +DRY+A+ + LRY T VTK + +  ++ +WI+    S  P     I++ ++ +G   +
Sbjct:   71 VFVTSLAAADLVVGLLVMPPGATLALTGHWPLGETGCELWTSVDVLCVTASIETLCALAVDRYLAVTNPLRYGTLVTKRRARAAVVLVWIVSAAVSFAP-----IMSQWWRVGADAE 182
[Close]
BLAST of GCR129 vs. Ensembl Mouse
Match: Hrh2 (histamine receptor H2 [Source:MGI Symbol;Acc:MGI:108482])

HSP 1 Score: 70.4774 bits (171), Expect = 7.308e-13
Identity = 43/141 (30.50%), Postives = 75/141 (53.19%), Query Frame = 2 
Query:  194 AERVIISGVMLILVVASIIGNVAVIVKLITLGKDFRRNHLIFIFNYAIIEFLLASFVMGVNAAYVISNQWILGNFICSLSCSVNYFCIISSTVTFSLLIIDRYMAICHSLRYNTFVTKSKIQLQILFIWIIGILFSTVPVH 616
            A +V IS V+  L+  ++ GNV V +  ++L +  R     FI + A  + LL   VM  +A Y +S +W  G   C++  S++     +S +   ++ +DRY A+   LRY   VT  ++ + ++FIW+I I  S + +H
Sbjct:   16 ALKVTISVVLTTLIFITVAGNVVVCLA-VSLNRRLRSLTNCFIVSLAATDLLLGLLVMPFSAIYQLSFKWSFGQVFCNIYTSLDVMLCTASILNLFMISLDRYCAVTDPLRYPVLVTPVRVAISLVFIWVISITLSFLSIH 155
[Close]
BLAST of GCR129 vs. UniProt/SwissProt
Match: sp|P04274|ADRB2_MESAU (Beta-2 adrenergic receptor OS=Mesocricetus auratus OX=10036 GN=ADRB2 PE=1 SV=1)

HSP 1 Score: 88.5817 bits (218), Expect = 5.698e-18
Identity = 85/312 (27.24%), Postives = 147/312 (47.12%), Query Frame = 2 
Query:  185 RTTAERVIISGVMLILVVASIIGNVAVIVKLITLGKDFRRNHLIFIFNYAIIEFLLASFVMGV-----NAAYVISNQWILGNFICSLSCSVNYFCIISSTVTFSLLIIDRYMAICHSLRYNTFVTKSKIQLQILFIWIIGILFSTVPV--------HQKAIITSYYELGCAVDWLAASSXXXXXXXXXXXXXXAIPLFVIMYCYYRI-------ISKIKEISQTFQSPNV--IPSNTISE---RISS-----DQKVIRSHEILLFAIVMSIGPYWISKILKMSQDQEFGPNYLTTAGSLVPLIGSLITPLIY 1030
            R  A  V ++ +M ++V+A + GNV VI  +      F R  L  + NY I     A  VMG+      A++++   W  GNF C    S++  C+ +S  T  ++ +DRY+AI    +Y + +TK+K ++ IL +WI+  L S +P+        HQKAI   + E  C  D+    ++ I     +F     +PL V+++ Y R+       + KI +    F SPN+  +  +  S    R SS     + K +++  I++    +   P++I  I+ + QD    P  +    + +  + S   PLIY
Sbjct:   28 RDEAWVVGMAILMSVIVLAIVFGNVLVITAI----AKFER--LQTVTNYFITSLACADLVMGLAVVPFGASHILMKMWNFGNFWCEFWTSIDVLCVTASIETLCVIAVDRYIAITSPFKYQSLLTKNKARMVILMVWIVSGLTSFLPIQMHWYRATHQKAIDCYHKETCC--DFFTNQAYAIASSIVSFY----VPLVVMVFVYSRVFQVAKRQLQKIDKSEGRFHSPNLGQVEQDGRSGHGLRRSSKFCLKEHKALKTLGIIMGTFTLCWLPFFIVNIVHVIQDNLI-PKEVYILLNWLGYVNSAFNPLIY 326
[Close]
BLAST of GCR129 vs. UniProt/SwissProt
Match: sp|Q8K4Z4|ADRB2_CAVPO (Beta-2 adrenergic receptor OS=Cavia porcellus OX=10141 GN=Adrb2 PE=3 SV=1)

HSP 1 Score: 84.3445 bits (207), Expect = 1.466e-16
Identity = 83/317 (26.18%), Postives = 140/317 (44.16%), Query Frame = 2 
Query:  167 EN*VSMRTTAERVIISGVMLILVVASIIGNVAVIVKLITLGKDFRRNHLIFIFNYAIIEFLLASFVMGV-----NAAYVISNQWILGNFICSLSCSVNYFCIISSTVTFSLLIIDRYMAICHSLRYNTFVTKSKIQLQILFIWIIGILFSTVPVH-------QKAIITSYYELGCAVDWLAASSXXXXXXXXXXXXXXAIPLFVIMYCYYRI-------ISKIKEISQTFQSPNVIPSNTISE-----RISS-----DQKVIRSHEILLFAIVMSIGPYWISKILKMSQDQEFGPNYLTTAGSLVPLIGSLITPLIY 1030
             N    R  A  V ++ VM ++V+A + GNV VI  +      F R  L  + NY I     A  VMG+      A++++ N W  GNF C    S++  C+ +S  T  ++ +DRY AI    +Y + +TK+K ++ IL +W++  L S +P+         K  I  Y E  C  D+    ++ I     +F     +PL V+++ Y R+       + KI      F + N+             R SS     + K +++  I++    +   P++I  I+ + QD    P  +    + V  + S   PLIY
Sbjct:   22 HNVTRERDEAWVVGMAIVMSLIVLAIVFGNVLVITAI----AKFER--LQTVTNYFITSLACADLVMGLAVVPFGASHILMNMWTFGNFWCEFWTSIDVLCVTASIETLCVIAVDRYFAITSPFKYQSLLTKNKARVVILMVWVVSGLTSFLPIQMHWYRATHKDAINCYAEETCC-DFFTNQAYAIASSIVSFY----LPLVVMVFVYSRVFQVAKKQLQKIDRSEGRFHTQNLSQVEQDGRSGHGLRRSSKFYLKEHKALKTLGIIMGTFTLCWLPFFIVNIVHVIQDNLI-PKEVYILLNWVGYVNSAFNPLIY 326
[Close]
BLAST of GCR129 vs. UniProt/SwissProt
Match: sp|Q28509|ADRB2_MACMU (Beta-2 adrenergic receptor OS=Macaca mulatta OX=9544 GN=ADRB2 PE=2 SV=1)

HSP 1 Score: 83.5741 bits (205), Expect = 2.968e-16
Identity = 82/312 (26.28%), Postives = 143/312 (45.83%), Query Frame = 2 
Query:  185 RTTAERVIISGVMLILVVASIIGNVAVIVKLITLGKDFRRNHLIFIFNYAIIEFLLASFVMGV-----NAAYVISNQWILGNFICSLSCSVNYFCIISSTVTFSLLIIDRYMAICHSLRYNTFVTKSKIQLQILFIWIIGILFSTVPV--------HQKAIITSYYELGCAVDWLAASSXXXXXXXXXXXXXXAIPLFVIMYCYYRIISKIK-EISQTFQSPNVIPSNTISE-----------RISS-----DQKVIRSHEILLFAIVMSIGPYWISKILKMSQDQEFGPNYLTTAGSLVPLIGSLITPLIY 1030
            R  A  V +  VM ++V+A + GNV VI  +      F R  L  + NY I     A  VMG+      AA+++   W  GNF C    S++  C+ +S  T  ++ +DRY AI    +Y + +TK+K ++ IL +WI+  L S +P+        HQ+AI     E  C  D+    ++ I     +F     +PL ++++ Y R+  + K ++ +  +S     +  +S+           R SS     + K +++  I++    +   P++I  I+ + QD    P  +    + V  + S   PLIY
Sbjct:   28 RDEAWVVGMGIVMSLIVLAIVFGNVLVITAI----AKFER--LQTVTNYFITSLACADLVMGLAVVPFGAAHILMKMWTFGNFWCEFWTSIDVLCVTASIETLCVIAVDRYFAITSPFKYQSLLTKNKARVIILMVWIVSGLTSFLPIQMHWYRATHQEAINCYAKETCC--DFFTNQAYAIASSIVSFY----VPLVIMVFVYSRVFQEAKRQLQKIDKSEGRFHAQNLSQVEQDGRTGHGLRRSSKFCLKEHKALKTLGIIMGTFTLCWLPFFIVNIVHVIQDNLI-PKEVYILLNWVGYVNSGFNPLIY 326
[Close]
BLAST of GCR129 vs. UniProt/SwissProt
Match: sp|P54833|ADRB2_CANLF (Beta-2 adrenergic receptor OS=Canis lupus familiaris OX=9615 GN=ADRB2 PE=2 SV=1)

HSP 1 Score: 83.1889 bits (204), Expect = 3.705e-16
Identity = 83/312 (26.60%), Postives = 142/312 (45.51%), Query Frame = 2 
Query:  185 RTTAERVIISGVMLILVVASIIGNVAVIVKLITLGKDFRRNHLIFIFNYAIIEFLLASFVMGV-----NAAYVISNQWILGNFICSLSCSVNYFCIISSTVTFSLLIIDRYMAICHSLRYNTFVTKSKIQLQILFIWIIGILFSTVPV--------HQKAIITSYYELGCAVDWLAASSXXXXXXXXXXXXXXAIPLFVIMYCYYRI-------ISKIKEISQTFQSPNV--IPSNTIS---ERISS-----DQKVIRSHEILLFAIVMSIGPYWISKILKMSQDQEFGPNYLTTAGSLVPLIGSLITPLIY 1030
            R+ A  V +  VM ++V+A + GNV VI  +       R   L  + NY I     A  VMG+      A++++   W  GNF C    S++  C+ +S  T  ++ +DRY AI    +Y + +TK+K ++ IL +WI+  L S +P+        HQ+AI     E  C  D+    ++ I     +F     +PL V+++ Y R+       + KI      F + N+  +  +  S    R SS     + K +++  I++    +   P++I  I+ + QD    P  +    + V  + S   PLIY
Sbjct:   28 RSEAWVVGMGIVMSLIVLAIVFGNVLVITAIA------RFERLQTVTNYFITSLACADLVMGLAVVPFGASHILMKMWTFGNFWCEFWTSIDVLCVTASIETLCVIAVDRYFAITSPFKYQSLLTKNKARVVILMVWIVSGLTSFLPIQMHWYRATHQEAINCYAKETCC--DFFTNQAYAIASSIVSFY----LPLVVMVFVYSRVFQVAQRQLQKIDRSEGRFHAQNLSQVEQDGRSGHGHRRSSKFCLKEHKALKTLGIIMGTFTLCWLPFFIVNIVHVIQDNLI-PKEVYILLNWVGYVNSAFNPLIY 326
[Close]
BLAST of GCR129 vs. UniProt/SwissProt
Match: sp|Q9TST5|ADRB2_FELCA (Beta-2 adrenergic receptor OS=Felis catus OX=9685 GN=ADRB2 PE=3 SV=1)

HSP 1 Score: 83.1889 bits (204), Expect = 4.286e-16
Identity = 82/312 (26.28%), Postives = 139/312 (44.55%), Query Frame = 2 
Query:  185 RTTAERVIISGVMLILVVASIIGNVAVIVKLITLGKDFRRNHLIFIFNYAIIEFLLASFVMGV-----NAAYVISNQWILGNFICSLSCSVNYFCIISSTVTFSLLIIDRYMAICHSLRYNTFVTKSKIQLQILFIWIIGILFSTVPV--------HQKAIITSYYELGCAVDWLAASSXXXXXXXXXXXXXXAIPLFVIMYCYYRI-------ISKIKEISQTFQSPNVIP------SNTISERIS----SDQKVIRSHEILLFAIVMSIGPYWISKILKMSQDQEFGPNYLTTAGSLVPLIGSLITPLIY 1030
            R  A  V +  VM ++V+A + GNV VI  +       R   L  + NY I     A  VMG+      A++++   W  GNF C    S++  C+ +S  T  ++ +DRY AI    +Y + +TK+K ++ IL +WI+  L S +P+        HQ+AI     E  C  D+    ++ I     +F     +PL V+++ Y R+       + KI +    F + N+        S     R S     + K +++  I++    +   P++I  I+ + QD    P  +    + V  + S   PLIY
Sbjct:   28 RNDAWVVGMGIVMSLIVLAIVFGNVLVITAIA------RFERLQTVTNYFITSLACADLVMGLAVVPFGASHILMKMWTFGNFWCEFWTSIDVLCVTASIETLCVIAVDRYFAITSPFKYQSLLTKNKARVVILMVWIVSGLTSFLPIQMHWYRATHQEAINCYAKETCC--DFFTNQAYAIASSIVSFY----LPLVVMVFVYSRVFQVAQRQLQKIDKSEGRFHAQNLSQVEQDGRSGHGHRRASKFCLKEHKALKTLGIIMGTFTLCWLPFFIVNIVHVIQDNLI-PKEVYILLNWVGYVNSAFNPLIY 326
[Close]
BLAST of GCR129 vs. TrEMBL
Match: A0A193KUE2 (GCR129 OS=Schmidtea mediterranea OX=79327 GN=gcr129 PE=2 SV=1)

HSP 1 Score: 573.163 bits (1476), Expect = 0.000e+0
Identity = 302/302 (100.00%), Postives = 302/302 (100.00%), Query Frame = 2 
Query:  182 MRTTAERVIISGVMLILVVASIIGNVAVIVKLITLGKDFRRNHLIFIFNYAIIEFLLASFVMGVNAAYVISNQWILGNFICSLSCSVNYFCIISSTVTFSLLIIDRYMAICHSLRYNTFVTKSKIQLQILFIWIIGILFSTVPVHQKAIITSYYELGCAVDWLAASSXXXXXXXXXXXXXXAIPLFVIMYCYYRIISKIKEISQTFQSPNVIPSNTISERISSDQKVIRSHEILLFAIVMSIGPYWISKILKMSQDQEFGPNYLTTAGSLVPLIGSLITPLIYVNMQTEICVVTEVEDGINV 1087
            MRTTAERVIISGVMLILVVASIIGNVAVIVKLITLGKDFRRNHLIFIFNYAIIEFLLASFVMGVNAAYVISNQWILGNFICSLSCSVNYFCIISSTVTFSLLIIDRYMAICHSLRYNTFVTKSKIQLQILFIWIIGILFSTVPVHQKAIITSYYELGCAVDWLAASSFIIVFVTFTFVLFFAIPLFVIMYCYYRIISKIKEISQTFQSPNVIPSNTISERISSDQKVIRSHEILLFAIVMSIGPYWISKILKMSQDQEFGPNYLTTAGSLVPLIGSLITPLIYVNMQTEICVVTEVEDGINV
Sbjct:    1 MRTTAERVIISGVMLILVVASIIGNVAVIVKLITLGKDFRRNHLIFIFNYAIIEFLLASFVMGVNAAYVISNQWILGNFICSLSCSVNYFCIISSTVTFSLLIIDRYMAICHSLRYNTFVTKSKIQLQILFIWIIGILFSTVPVHQKAIITSYYELGCAVDWLAASSFIIVFVTFTFVLFFAIPLFVIMYCYYRIISKIKEISQTFQSPNVIPSNTISERISSDQKVIRSHEILLFAIVMSIGPYWISKILKMSQDQEFGPNYLTTAGSLVPLIGSLITPLIYVNMQTEICVVTEVEDGINV 302
[Close]
BLAST of GCR129 vs. TrEMBL
Match: A0A1S3J8T4 (5-hydroxytryptamine receptor 4 OS=Lingula unguis OX=7574 GN=LOC106171058 PE=3 SV=1)

HSP 1 Score: 126.331 bits (316), Expect = 2.933e-29
Identity = 87/295 (29.49%), Postives = 154/295 (52.20%), Query Frame = 2 
Query:  185 RTTAERVIISGVMLI-LVVASIIGNVAVIVKLITLGKDFRRNHLIFIFNYAIIEFLLASFVMGVNAAYVISNQWILGNFICSLSCSVNYFCIISSTVTFSLLIIDRYMAICHSLRYNTFVTKSKIQLQILFIWIIGILFSTVPVHQKAIITSYYELGCAVDWLAASSXXXXXXXXXXXXXXAIPLFVIMYCY-----------YRIISKIKEISQTFQSP-NVIPSNTISERISSDQKVIRSHEILLFAIVMSIGPYWISKILKMSQDQEFGPNYLTTAGSLVPLIGSLITPLIY 1030
            R + E +II  + L+ +++ SI+GN++VIV + T  K + +   IFI N +I +   A FVM      +I++ W  G   C   C+ NY+ II S  T + + +DRY +I H L+Y  ++T  KI + + F WI+G++F+ VPV    +   Y+E+ CA++W       + +V   F++ F +P  +++ CY            RI + +   SQ+  S  N   ++  ++ I S+ KVI+S  I++    + + P+ ++K+LK+       P +L    + V  + S   P IY
Sbjct:   24 RRSLEAIIIGSIFLLAIILCSILGNISVIVAVWTYPKLYEQKASIFIVNLSITDLCNAIFVMIWTCCALITDGWPFGIMWCRFQCAFNYWLIIVSMQTLAWISVDRYHSIAHPLQYADYLTTKKIMMMLSFSWILGLIFAFVPVFLDWVHYDYWEVVCAINWHYQQDMAVFYVVIAFIVCFLVPAVIMVGCYSCIAYAANKCARRIEACVVPRSQSIASDSNSTGTSQTTKLIQSNTKVIKSLIIVVAVFFVCMTPFCVTKLLKVVFYNNIVPGWLNAFSTWVQFLSSASNPFIY 318
[Close]
BLAST of GCR129 vs. TrEMBL
Match: W4Y459 (G_PROTEIN_RECEP_F1_2 domain-containing protein OS=Strongylocentrotus purpuratus OX=7668 PE=3 SV=1)

HSP 1 Score: 115.931 bits (289), Expect = 1.730e-24
Identity = 96/334 (28.74%), Postives = 159/334 (47.60%), Query Frame = 2 
Query:  200 RVIISGVMLILVVASIIGNVAVIVKLITLGKDFRRN-HLIFIFNYAIIEFLLASFVMGVNAAYVISNQWILGNFICSLSCSVNYFCIISSTVTFSLLIIDRYMAICHSLRYNTFVTKSKIQLQILFIWIIGILFSTVPVHQKAIITSYYELGCAVDWLAASSXXXXXXXXXXXXXXAIPLFVIMYCY---YR-------------IISKIKEISQ---------TFQSP-----NVIPSNTISERISSD-------------------------QKVIRSHEILLFAIVMSIGPYWISKILKMSQ-DQEFGPNYLTTAGSLVPLIGSLITPLIY 1030
             ++++GV+ I++  +IIGN  V +  I+  +  R     +FI N AI +   AS VM  +   V  + WI GNF+C ++C  NY  II S ++ +L+ +DR++ + H  RY   VT  +  + +L  W++G +F+  P   + +I    E+ CAVDW +  S I+ +    FV+ F  P+ V+ YCY   YR             I+ +I EI Q         T Q+P     N+  SN I   +S++                          K IRS  +++ A V+   P+ ++K++K+ + + E  P Y+ TA S    I     P+IY
Sbjct:    8 EILLTGVLCIIICVAIIGNSMVCLA-ISRSRTLRAQVANVFIVNLAITDLGCASLVMPFSLVSVWFDHWIFGNFMCDVACFFNYCFIIVSMLSLALISVDRHIYVVHPFRYQGMVTHRRAFVLVLCTWLVGFIFAAAPPLMRWVIFDNAEIICAVDWESDHSKILAYTVSAFVMCFMSPILVMFYCYVGIYRVAKEHAKRIAPPHIVGRIGEIEQPPVQTPEYATEQTPEHVCRNLNGSNYIQREVSANGQSSTLTNTLKQSALIKSKSPGFYSNKAIRSILVMVLAYVLCNTPFSLTKLIKVIKINNEAVPFYINTAASWFGFINPCCNPIIY 340
[Close]
BLAST of GCR129 vs. TrEMBL
Match: R7UWE7 (G_PROTEIN_RECEP_F1_2 domain-containing protein (Fragment) OS=Capitella teleta OX=283909 GN=CAPTEDRAFT_54000 PE=4 SV=1)

HSP 1 Score: 108.227 bits (269), Expect = 4.125e-23
Identity = 70/276 (25.36%), Postives = 148/276 (53.62%), Query Frame = 2 
Query:  206 IISGVMLILVVASIIGNVAVIVKLITLGKDFRRNHLIFIFNYAIIEFLLASFVMGVNAAYVISNQWILGNFICSLSCSVNYFCIISSTVTFSLLIIDRYMAICHSLRYNTFVTKSKIQLQILFIWIIGILFSTVPVHQKAIITSYYELGCAVDWLAASSXXXXXXXXXXXXXXAIPLFVIMYCYYRIISKIKEISQTFQSPNVIPSNTISERISSDQKVIRSHEILLFAIVMSIGPYWISKILKMS-QDQEFGPNYLTTAGSLVPLIGSLITPLIY 1030
            ++S ++ +++  ++IGN  VIV + +  +   +   IFI N  + +   A  VMG     ++S+   +    C++ C+ NY  II S +T + + ++R +AI  ++RY+  VT+++++L   ++W+ G++F+  PV    I   Y+E+ CA+DW   S+  + +V   F + FA+P  ++++CY  II + + + +   S  +  S  + E      K I S  +++    + + P+ ++K+LK++ +D  +  ++     S    + S+I P +Y
Sbjct:    1 VLSTLLFLIMSMALIGNALVIVAIRSNHRLREQTSNIFIINLCVADLCSAIVVMGTVFYAILSDTHEINTIWCNIVCAANYCFIIVSMMTLAGISVERLIAIKTAMRYDVLVTRARVKLACAYVWLQGVIFAASPVGLGWIHYDYWEVVCAIDWQKESA--VYYVYVAFCVNFALPGLIMLFCYVAIIKEARRLKRVIPSELIPTSTQLRENQHQALKSITSLVVVVGLFFLCMTPFCLTKLLKVTVKDVHYIHDHTNLMASYFGYLSSMINPFVY 274
[Close]
BLAST of GCR129 vs. TrEMBL
Match: K1RP61 (Histamine H2 receptor OS=Crassostrea gigas OX=29159 GN=CGI_10020237 PE=3 SV=1)

HSP 1 Score: 103.219 bits (256), Expect = 6.696e-21
Identity = 84/286 (29.37%), Postives = 146/286 (51.05%), Query Frame = 2 
Query:  185 RTTAERVIISGVMLILVVASIIGNVAVIVKLIT--LGKDFRRNHLIFIFNYAIIEFLLASFVMGVNAAYVISNQWILGNFICSLSCSVNYFCIISSTVTFSLLIIDRYMAICHSLRYNTFVTKSKIQLQILFIWIIGILFSTVPVHQKAIITSYYELGCAVDWLAASSXXXXXXXXXXXXXXAIPLFVIMYCYYRIISKIKEISQTFQSPNVIPSNTISER-ISSDQKVIRSHEILLFAIVMSIGPYWISKILKMSQDQEFGPN-YLTTAGSLVPLIGSLITPLIY 1030
            R+  E   ++  + +++V S+ GN+AVIV + T  + ++   N L    N AI +      V+  +   VI++ W  G   C L C++NY  II+S +T   +  DR+ AI + L+Y   +    I L I + W  GI+FS VP     +   Y+E  CA+ W       + +V   F+L F +P  ++++ YY II +++       +    P + IS +  S+  K IRS  I++ A  + + P+ ++K++K++  QE   N +  +  S+V  I S + PLIY
Sbjct:   22 RSGVENAFLAFSLAVVMVFSVCGNLAVIVAIFTSRILREELSNRLTI--NLAITDLSNGLVVIFSSLFSVIADSWRFGPVYCDLICAINYCLIITSMLTLCFISCDRFQAITYPLQYINRMKPIHIYLMISYAWFQGIVFSAVPSALGWVEYDYWEAICAIQWQKEQKQAVYYVVVAFILCFLLPGLILIFNYYLIIKQVR-------TKVSCPGSPISAKSYSTSSKAIRSLLIVVIAYFVCMTPFSVTKLMKVTIAQETVLNSHFNSIASIVAFISSAVNPLIY 298
[Close]
BLAST of GCR129 vs. Ensembl Cavefish
Match: adrb2a (adrenoceptor beta 2 [Source:NCBI gene;Acc:103041180])

HSP 1 Score: 82.8037 bits (203), Expect = 5.328e-17
Identity = 69/258 (26.74%), Postives = 123/258 (47.67%), Query Frame = 2 
Query:  197 ERVIISGVMLILVVASIIGNVAVIVKLITLGKDFRRNHLIFIFNYAIIEFLLASFVMGV-----NAAYVISNQWILGNFICSLSCSVNYFCIISSTVTFSLLIIDRYMAICHSLRYNTFVTKSKIQLQILFIWIIGILFSTVPVHQKAIITSYYELG-CAVDWLAAS-SXXXXXXXXXXXXXXAIPLFVIMYCYYRIISKI-KEISQTFQSPNVIPSNTISE-----------RISSDQK-VIRSHEIL-LFAIVMSI 907
            + V++  V+ +LV+A ++GNV VI  +       R   L  + N  I+    A  VMG+      A ++I N W  G F C    + +  C+ +S  T  ++ +DRY+AI    RY + +TK K ++ +L +WIIG L S +P+H +  +++  E   C  D          ++   + ++ F IPL ++++ Y R+  +  K++ +  +S      N I +           RI+   K  +R H+ L    I+M I
Sbjct:   27 QMVLLGTVLSVLVLAIVLGNVLVITAIA------RFQRLQNVTNCFIMSLACADLVMGLIVVPFGAIHIILNNWYFGRFWCEFWTATDVLCVTASIETLCIIALDRYLAITSPFRYQSLLTKCKARIVVLLVWIIGALISYLPIHLRWYLSNSDEAQTCMKDASCCEFQPNRLYTIISSIISFYIPLVIMVFVYSRVFQEARKQLKKIDRSEGRFHHNGIGKGHQDANSSSDVRIAKKPKFCLREHKALKTLGIIMGI 278
[Close]
BLAST of GCR129 vs. Ensembl Cavefish
Match: adrb2b (beta-2 adrenergic receptor-like [Source:NCBI gene;Acc:103035250])

HSP 1 Score: 78.9518 bits (193), Expect = 1.025e-15
Identity = 46/148 (31.08%), Postives = 79/148 (53.38%), Query Frame = 2 
Query:  188 TTAERVIISGVMLILVVASIIGNVAVIVKLITLGKDFRRNHLI---FIFNYAIIEFLLASFVMGVNAAYVISNQWILGNFICSLSCSVNYFCIISSTVTFSLLIIDRYMAICHSLRYNTFVTKSKIQLQILFIWIIGILFSTVPVHQK 622
            + AE VI+  +M +LV+  + GNV VI  +      F+R   +   FI + A  + ++   V+   A Y++ N W  GNF C    + +  C+ +S  T  ++ +DRY+AI   LRY + +TK K    +L +W++  L S +P+H +
Sbjct:   40 SDAEMVILGILMGLLVLGIVFGNVLVITAI----ARFQRLQTVTNCFISSLACADLVMGLLVVPFGACYILLNTWHFGNFFCEFWTATDVLCVTASIETLCVIALDRYLAITWPLRYQSVLTKRKACWVVLAVWLVAGLISFLPIHME 183
[Close]
BLAST of GCR129 vs. Ensembl Cavefish
Match: adra1ba (adrenoceptor alpha 1B [Source:NCBI gene;Acc:103033427])

HSP 1 Score: 73.559 bits (179), Expect = 9.029e-14
Identity = 55/219 (25.11%), Postives = 107/219 (48.86%), Query Frame = 2 
Query:  218 VMLILVVASIIGNVAVIVKLITLGKDFRRNHLIFIFNYAIIEFLLASFVMGVNAAYVISNQWILGNFICSLSCSVNYFCIISSTVTFSLLIIDRYMAICHSLRYNTFVTKSKIQLQILFIWIIGILFSTVPVHQKAIITSYYELGCAVDWLAASSXXXXXXXXXXXXXXAIPLFVIMYCYYRIISKIKEISQTFQSPNVIPSNTISERISSDQKVIRSH 874
            V+   +V +I+GN+ VI+ ++   +  R     FI N A+ + LL + V+ V+A   I N W+ G   C +  +V+  C  +S ++  ++ IDRY+ + + L+Y + VT+ +  L +L +W++  + S  P      +  + E     D +   +    +  F+ +  F IPL VI+  Y R+    K  ++  +      +  + ER+ S +  +R H
Sbjct:   51 VLGAFIVFAIVGNILVILSVV-CNRHLRIPTNYFIINLAMADLLLGTTVLPVSATLEILNYWVFGRIFCDIWAAVDVLCCTASIMSLCVISIDRYIGVRYPLQYPSIVTEKRALLAMLGVWVLATVISIGP------LLGWKEPPSDDDTICPITEEPFYALFSSLGSFYIPLAVILAMYCRVYIVAKRTTRNLE------AGVMKERMDSSELTLRIH 256
[Close]
BLAST of GCR129 vs. Ensembl Cavefish
Match: ENSAMXT00000052904.1 (pep primary_assembly:Astyanax_mexicanus-2.0:21:18347467:18356662:-1 gene:ENSAMXG00000034261.1 transcript:ENSAMXT00000052904.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 72.4034 bits (176), Expect = 2.160e-13
Identity = 54/207 (26.09%), Postives = 111/207 (53.62%), Query Frame = 2 
Query:  197 ERVIISGVMLILVVASIIGNVAVIVKLITLGKDFRRNHLIFIFNYAIIEFLLASFVMGVNAAYVISNQWILGNFIC-SLSCSVNYFCIISSTVTFSLLIIDRYMAICHSLRYNTFVTKSKIQLQILFIWIIGILFSTVPV---HQKAIITSYYELGCAVDWLAASSXXXXXXXXXXXXXXAIPLFVIMYCYYRIISKIKEISQTFQS 805
            E+V++  +M+++ V ++ GN+ VIV ++   K F     + I N AI +FL+   VM   A  +++N W+  N +C  +  + + +C  +S +T + + +DRY +I   LRY++  T  +    +L+IW+  +L S+ P+      + ++  Y   C V+W ++ S+ +     +F+    +P  VI++CY +I+   +  ++   S
Sbjct:   37 EKVLLEVLMVLMCVGAVTGNILVIV-IVVATKTFHSVTSVLIINLAISDFLVGIGVMPFVAVSIMNNGWVNCNDLCLYVGYTSSVYC-TASVLTLAAIALDRYYSIVDCLRYDSRCTVWRTGAAVLWIWLQAMLTSSPPLLGWSNVSFVSPMYS--CVVNWASSPSYTVFMAALSFL----LPATVILFCYVKIVRVARHHARRIHS 235
[Close]
BLAST of GCR129 vs. Ensembl Cavefish
Match: adra1aa (alpha-1A adrenergic receptor-like [Source:NCBI gene;Acc:103024013])

HSP 1 Score: 71.2478 bits (173), Expect = 3.857e-13
Identity = 37/137 (27.01%), Postives = 75/137 (54.74%), Query Frame = 2 
Query:  203 VIISGVMLILVVASIIGNVAVIVKLITLGKDFRRNHLIFIFNYAIIEFLLASFVMGVNAAYVISNQWILGNFICSLSCSVNYFCIISSTVTFSLLIIDRYMAICHSLRYNTFVTKSKIQLQILFIWIIGILFSTVPV 613
            V++  V+ I +V  ++GN+ VI+  +   ++ R     FI N A+ + LL+S V+  +A + +   W+ G   C +  +++  C  +S ++   + +DRY+ + + LRY T VT+ +  L ++ +W + I  S  P+
Sbjct:   41 VVLGIVLAIFIVFGVMGNILVILS-VACHRNLRTVTHYFIANLAVADLLLSSTVLPFSAIFEMLGHWVFGRAFCDVWAAMDVLCCTASIMSLCAISVDRYIGVSYPLRYPTIVTERRALLALMGVWALSITISVGPL 176
[Close]
BLAST of GCR129 vs. Ensembl Sea Lamprey
Match: HTR1F (5-hydroxytryptamine receptor 1F [Source:HGNC Symbol;Acc:HGNC:5292])

HSP 1 Score: 64.6994 bits (156), Expect = 9.813e-12
Identity = 33/118 (27.97%), Postives = 60/118 (50.85%), Query Frame = 2 
Query:  260 AVIVKLITLGKDFRRNHLIFIFNYAIIEFLLASFVMGVNAAYVISNQWILGNFICSLSCSVNYFCIISSTVTFSLLIIDRYMAICHSLRYNTFVTKSKIQLQILFIWIIGILFSTVPV 613
            A+++  I+  +  R+     I + A+ + L+A+ VM V AAYV++ +W LG  +C L  S++  C  +S +    + +DR+ AI  +  Y    T  +  L I   W++    S  P+
Sbjct:   66 ALVIAAISATRKLRQPANYLIGSLAVADLLVAALVMPVAAAYVVTGEWALGGALCDLWLSLDVTCCTASILHLCAIALDRFWAITDAAEYAHKRTPGRAALMIAASWLLAACISVPPL 183
[Close]
BLAST of GCR129 vs. Ensembl Sea Lamprey
Match: TAAR1 (trace amine associated receptor 1 [Source:HGNC Symbol;Acc:HGNC:17734])

HSP 1 Score: 62.7734 bits (151), Expect = 2.870e-11
Identity = 34/132 (25.76%), Postives = 67/132 (50.76%), Query Frame = 2 
Query:  203 VIISGVMLILVVASIIGNVAVIVKLITLGKDFRRNHLIFIFNYAIIEFLLASFVMGVNAAYVISNQWILGNFICSLSCSVNYFCIISSTVTFSLLIIDRYMAICHSLRYNTFVTKSKIQLQILFIWIIGILF 598
            +++ GV+L  ++++I+GN+ VI  +I   K  + +      + A  + L+   VM  +    + + W  G  +C L CS++Y     S +  S +  DRY+AIC  L Y + VT + +   ++  W   +++
Sbjct:   30 LVVQGVLLFFIISTILGNMLVIASIIYF-KQLQSHTNSLTLSLAAADLLVGLVVMPFSMMRTVHSCWFYGKLLCKLHCSLDYIFSTVSILHLSCVAFDRYVAICDPLHYTSRVTNNTVAFMLILCWTCPLVY 160
[Close]
BLAST of GCR129 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000008360.1 (pep scaffold:Pmarinus_7.0:GL477173:168532:170490:1 gene:ENSPMAG00000007563.1 transcript:ENSPMAT00000008360.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 60.4622 bits (145), Expect = 2.661e-10
Identity = 33/128 (25.78%), Postives = 67/128 (52.34%), Query Frame = 2 
Query:  230 LVVASIIGNVAVIVKLITLGKDFRRNHLIFIFNYAIIEFLLASFVMGVNAAYVISNQWILGNFICSLSCSVNYFCIISSTVTFSLLIIDRYMAICHSLRYNTFVTKSKIQLQILFIWIIGILFSTVPV 613
            +++ +I GN  V + + T  K  +    +F+ + A  + L+A+ VM  + A  +   W+ G+F C +  +++     SS V    + +DRY ++  ++RYN   T  +++  I+ +W+I  L S  P+
Sbjct:   43 IILVTIFGNSLVAIAVFT-SKSLKAAQNLFLVSLAAADILVATLVMPFSLANELMGYWVFGSFWCEMYLALDVLFCTSSIVHLCAISLDRYWSVTQAVRYNMKRTPRRVKRAIVIVWVIAALISFPPL 169
[Close]
BLAST of GCR129 vs. Ensembl Sea Lamprey
Match: oprk1 (opioid receptor, kappa 1 [Source:ZFIN;Acc:ZDB-GENE-030729-1])

HSP 1 Score: 58.151 bits (139), Expect = 7.113e-10
Identity = 29/91 (31.87%), Postives = 56/91 (61.54%), Query Frame = 2 
Query:  317 FIFNYAIIEFLLASFVMGVNAAYVISNQWILGNFICSLSCSVNYFCIISSTVTFSLLIIDRYMAICHSLRYNTFVTKSKIQLQILFIWIIG 589
            +IFN A+ + L+ + +   +A Y++ + W  G  IC +  S++Y+ + +S  T +++ +DRY+A+CH ++   F T SK +L  + IWI+ 
Sbjct:   13 YIFNLALADTLVTTTLPFQSADYLMGS-WPFGEVICKVVMSIDYYNMFTSIFTLTIMSVDRYIAVCHPVKALDFRTPSKAKLINICIWILS 102
[Close]
BLAST of GCR129 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000010661.1 (pep scaffold:Pmarinus_7.0:GL479584:296:6514:-1 gene:ENSPMAG00000009652.1 transcript:ENSPMAT00000010661.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 58.151 bits (139), Expect = 7.558e-10
Identity = 36/119 (30.25%), Postives = 62/119 (52.10%), Query Frame = 2 
Query:  236 VASIIGNVAVIVKLITLGKDFRRNHLIFIFNYAIIEFLLASFVMGVNAAYVISNQWILGNFICSLSCSVNYFCIISSTVTFSLLIIDRYMAICHSLRYNTFVTKSKIQLQILFIWIIGI 592
            V ++ GN AV+V ++ LG+  R +   F+ N A+ +  +A F +      V+   W+ G  +C L        +  S  T + + IDRY A+CH L  ++ +TKS+ ++ I  IW + I
Sbjct:   11 VLALSGN-AVVVWVLALGRRARTDISAFLINLALADLTMALFCLPFTFTEVLLQSWLFGALLCPLVRFAQTLSVSVSIYTLTTIGIDRYYAVCHPL--HSRMTKSRGKVLIALIWAVSI 126
[Close]
BLAST of GCR129 vs. Ensembl Nematostella
Match: EDO31716 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SX59])

HSP 1 Score: 74.7146 bits (182), Expect = 6.299e-15
Identity = 71/294 (24.15%), Postives = 136/294 (46.26%), Query Frame = 2 
Query:  221 MLILVVASIIGNVAVIVKLITLGKDFRRN-HLIFIFNYAIIEFLLASFVMGVNAAYVISNQWILGNFICSLSCSVNYFCIISSTVTFSLLIIDRYMAICHSLRYNTFVTKSKIQLQILFIWIIGILFSTVPVHQKAIITSYYELG-----CAVDWLAASSXXXXXXXXXXXXXXAIPLFVIMYCYYRI--ISKIKE-------ISQTFQSPNVIPSNTISERISSDQKVIRSHEILLF---AIVMSIGPYWISKILKMSQDQEFGPNYLTTAGSLVPLIGSLITPLIYVNMQTE 1048
            +  + +A+++ N  V + ++   K+ RR+   +FI N A+ +F+++ F M  +   V+ N W  GNF C  +   N    +++ +T + + IDRY+A+   L+Y   +T     + I+F+WI   +F+  P+        +YE       C       +   I F   T+     + L +++  YY+I  ++K+         IS    +P V  + +     SS Q+  ++   +LF   A V  + PY   +++++ +  +   + LT A S V  + S I P IY  +Q  
Sbjct:   16 LFFMTLAAVVMNFLVCL-VVYRSKELRRHISSVFIVNLAVCDFMMSIFAMPYSFGAVVVNHWPFGNFWCQTTGFWNLVLSLAAVLTLATISIDRYIAVIKPLQYRAKMTLQWALVMIVFVWIQATVFAIAPIG-----LGWYEFNSHYFFCTFPSELQTVEYIAFKVLTYTANVGVSLLILLSTYYKIFGVAKLHSRRIGHAVISTVHFAPGVRGAMSTE---SSRQREFKAARKILFVIGAFVCCVAPYTTIRLIELVKGYQPLSHRLTIAFSWVAYLKSAIDPFIYGLLQRR 300
[Close]
BLAST of GCR129 vs. Ensembl Nematostella
Match: EDO39352 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SAD3])

HSP 1 Score: 70.8626 bits (172), Expect = 9.929e-14
Identity = 70/277 (25.27%), Postives = 119/277 (42.96%), Query Frame = 2 
Query:  230 LVVASIIGNVAVIVKLITLGKDFRRNHLIFIFNYAIIEFLLASFVMGVNAAYVISNQWILGNFICSLSCSVNYFCIISSTVTFSLLIIDRYMAICHSLRYNTFVTKSKIQLQILFIWIIGILFSTVP-VHQKAIITSYYELGCAVDWLAASSXXXXXXXXXXXXXXAIPLFVIMYCYYRIISKIKE---------ISQTFQSPNVIPSNTISERISSDQKVIRSHEILLFAIVMSIGPYWISKILKMSQDQEFGPNYLTTAGSLVPLIGSLITPLIY 1030
            L++A IIGN  V+V LI L +        F+ N +  E L+    + +  A V+  +W  G  +C     V    + +S +T  ++ +DR++ I   LRY   +TK +  + I  IW   + ++ +P V    I        C  D+ A+     V+     V  FAIP  V  YC+ +I    KE         + + F S +V     ++     ++K  ++  I++ A V+   PY I    K++        +    G  + L  S + PLIY
Sbjct:   23 LILAIIIGNSLVLV-LIRLNRRLHSPTFYFLGNLSFAELLIGVGFVPLYTAAVLEGRWRFGKTMCRAHAFVVTSSVNASLITLCVVSVDRFLDIRDPLRYFGRMTKRRSAMIIFCIWAHSLFWAAMPLVDWGEISFDNNTKTCRPDFAASGISNRVYAALLVVFGFAIPSLVTGYCHIKIYQMAKEQTRKIAKISVRKDFTSGHVQEDIVLTFHPRKERKAHKTILIIIGAFVVCWLPYSIGTSWKLATGHALELYWFANVGLTLALTNSSLNPLIY 298
[Close]
BLAST of GCR129 vs. Ensembl Nematostella
Match: EDO37058 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SGY4])

HSP 1 Score: 67.781 bits (164), Expect = 1.512e-12
Identity = 62/314 (19.75%), Postives = 135/314 (42.99%), Query Frame = 2 
Query:  164 LEN*VSMRTTAERVIISGVMLILVVASIIGNVAVIVKLITLGKDFRRNHLI---FIFNYAIIEFLLASFVMGVNAAYVISNQWILGNFICSLSCSVNYFCIISSTVTFSLLIIDRYMAICHSLRYNTFVTKSKIQLQILFIWIIGILFSTVPV-------HQKAIITSYYELGCAVDWLAASSXXXXXXXXXXXXXXAIPLFVIMYCYYRIISKIKEISQTFQS--------------PNVIPSNTISERISSDQKVIRSHEILLFAIVMSIGPYWISKILKMS-QDQEFGPNYLTTAGSLVPLIGSLITPLIY 1030
            +++ V + T  E    + +++++++    GN+AV V +    KD      I    IFN A+ + L  + V+    + +    W+ G+F C  +  + Y   I S  + + + +DR+ AIC  L+Y + VT  ++   I+  W+  I+F+T  +        Q   + +Y   G    W  A      +   T +    +P  +++Y Y RI + ++  ++   +               N  P       +++  K  R+  +++   ++S  P+ +++++K+   + E  P    T  ++   + +   PL Y
Sbjct:    1 MQSRVDLLTAGEEAAFTTLLILILIFGFFGNIAVCVAIC---KDHHLRQQIPNALIFNLALTDLLTVTLVVPFCVSAIQREDWVFGHFWCQTTAFLYYTFAIVSLESLAFISLDRFYAICRPLQYRSAVTTKRLIPVIMLSWVWAIVFTTPCIFMGWFRFGQYESLCTYTFDGTGEKWKTAVI---TYSIITIITCIVVPFLLLLYSYVRIFAAVRHQNKRVATQQQLQHQQQLQHQQSNNRPRRRTLWNVNTAYKGYRTIVLIVILFLLSWAPFSVTRLIKIFLWNHEAVPAGADTFATVFSFLSAAANPLAY 308
[Close]
BLAST of GCR129 vs. Ensembl Nematostella
Match: EDO35245 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SM13])

HSP 1 Score: 64.6994 bits (156), Expect = 1.263e-11
Identity = 74/302 (24.50%), Postives = 130/302 (43.05%), Query Frame = 2 
Query:  185 RTTAERVIISGVMLILVVASIIGNVAVIVKLITLGKDFRRNHLIFIFNYAIIEFLLASFVMGVNAAYV------ISNQWILGNFICSLSCSVNYFCIISSTVTFSLLIIDRYMAICHSLRYNTFVTKSKIQLQILFIWIIGILFSTVPVHQKAIITSYYELG-CAVDWLAASSXXXXXXXXXXXXXXAIPLFVIMYCYYRIIS----KIKEISQTFQSPNVIPSNTISERIS---SDQKVIRSHEILLFAIVMSIGPYWISKILKMSQDQEFGPNYLTTAGS------LVPLIGSLITPLIY 1030
            R+  ERVI + V+ I+ + S++GN  V     T+  D+R +   F F   I    +A  ++G  A YV      + + W  G   C +          +S VT +L+  DRY+AI   LRY  F+T  +    I   W+  + ++  P      I    +   C ++W +      V+  F     F IP  +++YCY +I       +K+I Q          N++S + S   +D + +++  I++ A  ++  PY +  + K+     F P  +    +       V L+   I P+IY
Sbjct:   16 RSIGERVIQAIVLSIICLTSVLGNALVAA---TIHFDYRLHKPTFYF---IASLSVADIIVG--AVYVPFFAVAVLDGWGFGTIWCDVLAVTVSLSFNASLVTLALVSWDRYLAITKPLRYQAFMTSERAAALIAGAWVHSLFWAASPSVGWGEIAFDLDTNICRIEWSSKVESSKVYSLFLAFFAFFIPTAIMIYCYCKIFKVARHHVKQIKQ----------NSVSSQQSVTVNDTRALKTILIVIGAFAVAWLPYTMFSLTKL-----FAPGVVKVEATGSNAVLTVTLLNGCINPVIY 294
[Close]
BLAST of GCR129 vs. Ensembl Nematostella
Match: EDO38342 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SD89])

HSP 1 Score: 63.929 bits (154), Expect = 2.735e-11
Identity = 56/229 (24.45%), Postives = 107/229 (46.72%), Query Frame = 2 
Query:  230 LVVASIIGNVAVIVKLITLGKDFRRNHLIFIFNYAIIEFLLASFVMGVNAAYVISNQWILGNFICSLSCSVNYFCIISSTVTFSLLIIDRYMAICHSLRYNTFVTKSKIQLQILFIWIIGILFSTVPVHQKAIITSYYELGCAVDWLAASSXXXXXXXXXXXXXXAIPLFVIMYCYYRIISKIKEISQTFQSPNVIPSNTISERISSDQKVIRSHEILLFAIVMSIGPY 916
            ++V +IIGN ++I+  I   +  +    +F+ N AI +  LA   M       I+ +WI G+  C +    N     +S +T + + ++R++AI H L+Y  ++T   I++ +++IW+  ++ +T            +E  C VDW    S+ I +  F  V FF +P   +  CY+ I+ K  E  +   S   I    I  + + +Q+  +        I + +G +
Sbjct:   47 IIVTAIIGN-SLILTAIYRFRSLQTKTNVFVVNLAIADISLAVLAMPFTMTSSITYEWIFGDTFCKVQGIFNSLFCEASILTLTFVSLERFIAILHPLKYQQWMTPRTIKIMVVYIWLQSLICATSTFLFSKFEFLKFEHICTVDW----SYSIGYTFFFVVTFFFLPFAAMAVCYFVILRKALEQRRKIAS---ITVGEIRGQSNEEQRKTKQEHKATIMIAIVVGTF 267
[Close]
BLAST of GCR129 vs. Ensembl Medaka
Match: ENSORLT00000006865.2 (alpha-1A adrenergic receptor [Source:NCBI gene;Acc:101159926])

HSP 1 Score: 76.2554 bits (186), Expect = 1.085e-14
Identity = 54/225 (24.00%), Postives = 113/225 (50.22%), Query Frame = 2 
Query:  203 VIISGVMLILVVASIIGNVAVIVKLITLGKDFRRNHLIFIFNYAIIEFLLASFVMGVNAAYVISNQWILGNFICSLSCSVNYFCIISSTVTFSLLIIDRYMAICHSLRYNTFVTKSKIQLQILFIWIIGILFSTVPVHQKAIITSYYELGCAVDWLAASSXXXXXXXXXXXXXXAIPLFVIMYCYYRIISKIKEISQTFQSPNVIPSNTISERISSDQKVIRSHE 877
            ++++ V+   +V +I GN+ VI+ ++   +  R     FI N A+ + LL + V+ V+A   I N W+ G   C +  +++  C  +S ++  ++ IDRY+ + H L+Y   VT+ +  L +L +W++ ++ S  P+       S  ++ C +      +    +  F+ +  F IPL VI+  Y R+    K  ++  +      +  + ER+++ +  +R H+
Sbjct:   48 IVLALVLGAFIVFAIAGNILVILSVVC-NRHLRTPTNYFIINLAMADLLLGTTVLPVSATKEILNYWVFGRIFCDIWAALDVLCCTASIMSLCVISIDRYIGVSHPLQYPGIVTEKRALLAMLGVWVLSVVISIGPLLGWKQPPSDDDMECLI------TEEPFYALFSSLGSFYIPLAVILAMYCRVYIVAKRTTRNLE------AGVMRERMNTSELTLRIHK 259
[Close]
BLAST of GCR129 vs. Ensembl Medaka
Match: adra1aa (alpha-1A adrenergic receptor [Source:NCBI gene;Acc:101157705])

HSP 1 Score: 76.2554 bits (186), Expect = 1.155e-14
Identity = 53/230 (23.04%), Postives = 115/230 (50.00%), Query Frame = 2 
Query:  188 TTAERVIISGVMLILVVASIIGNVAVIVKLITLGKDFRRNHLIFIFNYAIIEFLLASFVMGVNAAYVISNQWILGNFICSLSCSVNYFCIISSTVTFSLLIIDRYMAICHSLRYNTFVTKSKIQLQILFIWIIGILFSTVPVHQKAIITSYYELGCAVDWLAASSXXXXXXXXXXXXXXAIPLFVIMYCYYRIISKIKEISQTFQSPNVIPSNTISERISSDQKVIRSHE 877
             T + V++  V+ I ++  +IGN+ VI+ ++   +  +     FI N A+ + LL+S V+  +A + I ++W+ G   C++  +V+  C  +S ++  ++ +DRY+ + + LRY   +TK +  L ++ +W++ ++ S  P+          E  C +      +    +  F+ V  F +PL +I+  Y R+    ++ S+  +          +E+  S+Q ++R H 
Sbjct:   29 NTVKAVVLGMVLGIFILFGVIGNILVILSVVC-HRHLQTVTYYFIVNLAVADLLLSSTVLPFSAIFEILDRWVFGRVFCNIWAAVDVLCCTASIMSLCVISVDRYIGVSYPLRYPAIMTKRRALLAVMLLWVLSVIISIGPLFGWKEPAPEDETVCKI------TEEPGYAIFSAVGSFYLPLAIILAMYCRVYVVAQKESRGLK------EGQKTEKSDSEQVILRMHR 245
[Close]
BLAST of GCR129 vs. Ensembl Medaka
Match: ENSORLT00000002753.2 (beta-2 adrenergic receptor [Source:NCBI gene;Acc:101159524])

HSP 1 Score: 75.8702 bits (185), Expect = 1.474e-14
Identity = 46/150 (30.67%), Postives = 81/150 (54.00%), Query Frame = 2 
Query:  188 TTAERVIISGVMLILVVASIIGNVAVIVKLITLGKDFRRNHLIFIFNYAIIEFLLASFVMGV-----NAAYVISNQWILGNFICSLSCSVNYFCIISSTVTFSLLIIDRYMAICHSLRYNTFVTKSKIQLQILFIWIIGILFSTVPVHQK 622
            + AE V+++  M ILV+A + GNV VI  ++      R + L  + N  I    +A  +MGV     +++ ++   W  GNF+C    + +  C+ +S  T  ++ +DRY+AI   LRY T +T+++    IL +W +  L S +P++ K
Sbjct:   21 SDAELVLLAVAMAILVLAIVFGNVMVISAIL------RFHRLQTVTNLFIASLAVADLIMGVVVVPFSSSNILLRSWKFGNFMCEFWTAADVLCVTASIETLCVIALDRYLAITLPLRYPTLLTRARAFAAILAVWAVASLISFLPIYLK 164
[Close]
BLAST of GCR129 vs. Ensembl Medaka
Match: adrb1 (adrenoceptor beta 1 [Source:ZFIN;Acc:ZDB-GENE-081022-145])

HSP 1 Score: 73.559 bits (179), Expect = 5.782e-14
Identity = 62/262 (23.66%), Postives = 127/262 (48.47%), Query Frame = 2 
Query:  209 ISGVMLILVVASIIGNVAVIVKLITLGKDFRRNHL--IFIFNYAIIEFLLASFVMGVNAAYVISNQWILGNFICSLSCSVNYFCIISSTVTFSLLIIDRYMAICHSLRYNTFVTKSKIQLQILFIWIIGILFSTVPV----HQKAIITSYYELGCAVDWLAASSXXXXXXXXXXXXXXAIPLFVIMYCYYRI-------ISKIKEISQTFQSPNVIPSNTISERISS-----DQKVIRSHEILLFAIVMSIGPYWISKILKM 940
            +S VM ++V++ + GN+ VI   + + +  R   L  +FI + A  + ++   V+   A   +   W+ G+F C +  SV+  C+ +S  T  ++ IDRY+AI    RY + +TKS+ +  +  +W I  L S +P+     + ++ T  YE     D++   ++ I     +F     IPL V+++ Y R+       + KI +    F +     ++   +R S      +QK +++  I++    +   P++I  ++++
Sbjct:   45 MSLVMALIVLSIVFGNILVI---LAIARTQRLQTLTNVFIVSLASADLIMGLLVVPFGAVLEVRGLWLYGSFFCEIWTSVDVLCVTASIETLCVIAIDRYVAITSPFRYQSLLTKSRAKAVVCVVWAISALVSFLPILMHWSRDSMDTDCYENPQCCDFVTNRAYAISSSVISFY----IPLVVMIFVYARVYREAKKQLKKIDKCEGRFHNTLTGLTSKCKKRPSKILALREQKALKTLGIIMGTFTLCWLPFFIVNVVRV 299
[Close]
BLAST of GCR129 vs. Ensembl Medaka
Match: adrb3a (adrenoceptor beta 3a [Source:ZFIN;Acc:ZDB-GENE-080917-21])

HSP 1 Score: 73.1738 bits (178), Expect = 8.557e-14
Identity = 35/134 (26.12%), Postives = 78/134 (58.21%), Query Frame = 2 
Query:  218 VMLILVVASIIGNVAVIVKLITLGKDFRRNHLIFIFNYAIIEFLLASFVMGVNAAYVISNQWILGNFICSLSCSVNYFCIISSTVTFSLLIIDRYMAICHSLRYNTFVTKSKIQLQILFIWIIGILFSTVPVHQ 619
            V++ +++ +++GN+ VI+  +      + +  IFI + A  + ++   V+ + A+YV+  +W LG  +C +  S++  C+ +S  T  ++ +DRY+AI   LR+   ++K + ++ +  +W++  L S VP+ Q
Sbjct:   21 VLVNIILITVVGNLLVIIA-VARTPQLQTSTNIFIMSLACADLIMGVLVVPLGASYVVIGKWELGTTLCDIWTSIDVLCVTASIETLCVIAVDRYIAITRPLRHKVLLSKLRARIIVCLVWLVSTLISFVPIMQ 153
[Close]
BLAST of GCR129 vs. Planmine SMEST
Match: SMESG000059005.1 (SMESG000059005.1)

HSP 1 Score: 571.622 bits (1472), Expect = 0.000e+0
Identity = 301/301 (100.00%), Postives = 301/301 (100.00%), Query Frame = 2 
Query:  182 MRTTAERVIISGVMLILVVASIIGNVAVIVKLITLGKDFRRNHLIFIFNYAIIEFLLASFVMGVNAAYVISNQWILGNFICSLSCSVNYFCIISSTVTFSLLIIDRYMAICHSLRYNTFVTKSKIQLQILFIWIIGILFSTVPVHQKAIITSYYELGCAVDWLAASSXXXXXXXXXXXXXXAIPLFVIMYCYYRIISKIKEISQTFQSPNVIPSNTISERISSDQKVIRSHEILLFAIVMSIGPYWISKILKMSQDQEFGPNYLTTAGSLVPLIGSLITPLIYVNMQTEICVVTEVEDGIN 1084
            MRTTAERVIISGVMLILVVASIIGNVAVIVKLITLGKDFRRNHLIFIFNYAIIEFLLASFVMGVNAAYVISNQWILGNFICSLSCSVNYFCIISSTVTFSLLIIDRYMAICHSLRYNTFVTKSKIQLQILFIWIIGILFSTVPVHQKAIITSYYELGCAVDWLAASSFIIVFVTFTFVLFFAIPLFVIMYCYYRIISKIKEISQTFQSPNVIPSNTISERISSDQKVIRSHEILLFAIVMSIGPYWISKILKMSQDQEFGPNYLTTAGSLVPLIGSLITPLIYVNMQTEICVVTEVEDGIN
Sbjct:    1 MRTTAERVIISGVMLILVVASIIGNVAVIVKLITLGKDFRRNHLIFIFNYAIIEFLLASFVMGVNAAYVISNQWILGNFICSLSCSVNYFCIISSTVTFSLLIIDRYMAICHSLRYNTFVTKSKIQLQILFIWIIGILFSTVPVHQKAIITSYYELGCAVDWLAASSFIIVFVTFTFVLFFAIPLFVIMYCYYRIISKIKEISQTFQSPNVIPSNTISERISSDQKVIRSHEILLFAIVMSIGPYWISKILKMSQDQEFGPNYLTTAGSLVPLIGSLITPLIYVNMQTEICVVTEVEDGIN 301
[Close]
BLAST of GCR129 vs. Planmine SMEST
Match: SMESG000055001.1 (SMESG000055001.1)

HSP 1 Score: 73.1738 bits (178), Expect = 6.768e-14
Identity = 41/137 (29.93%), Postives = 78/137 (56.93%), Query Frame = 2 
Query:  230 LVVASIIGNVAVIVKLITLGKDFRRNHLIFIFNYAIIEFLLASFVMGVNAAYVISNQ-WILGNFICSLSCSVNYFCIISSTVTFSLLIIDRYMAICHSLRYNTFVTKSKIQLQILFIWIIGILFSTVPVHQKAIITS 637
            ++++++ GNV VI+ +I   K    NH +F+ + A+ + L+A FVM  N   +++N  W  G+ +C +  S + F   +S +    + +DR+ AI H L Y++ +TK+++ L +L  W   IL S +P++     T+
Sbjct:   34 VIISAVFGNVLVILSVILYRKIRTLNHNLFVLSLAMADVLVALFVMPFNLTQIVTNGFWPFGSLMCEIYNSNDVFLSTASIIHLCCISMDRHFAIIHPLTYDSIMTKTRVGLMLLGCWTSSILISYIPIYSGLYTTN 170
[Close]
BLAST of GCR129 vs. Planmine SMEST
Match: SMESG000023113.1 (SMESG000023113.1)

HSP 1 Score: 71.633 bits (174), Expect = 1.559e-13
Identity = 67/288 (23.26%), Postives = 130/288 (45.14%), Query Frame = 2 
Query:  200 RVIISGVMLILVVASIIGNVAVIVKLITLGKDFRRNHLIFIFNYAIIEFLLASFVMGVNAAYVISNQWILGNFICSLSCSVNYFCIISSTVTFSLLIIDRYMAICHSLRYNTFVTKSKIQLQILFIWIIGILFSTVPVHQKAI----ITSYYELGCAVDWLAASSXXXXXXXXXXXXXXAIPLFVIMYCYYRIIS-KIKEISQTFQSPNVIPSNTISERISSDQKVIRSHEILLFAIVMSIGPYWISKILKMSQDQEFGPNYLTTAGSLVPLIGSLITPLIYVNMQTE 1048
            R+ +S +M ++++ ++ GN  V+V +I   +   +    F+ + AI +  +A FVM V+  Y +   W  G   C    S +  C  +S +    + IDRY++I H LRY T +T  +    I+ IW++ +L S VP++            +   C +D    +    +  + T      + L VI +  YRI S + K+I           S + S++  +D+K I++  +++    +   P++I  +++      F  N      + +  + S   P++Y   Q E
Sbjct:   17 RICLSFLMNLIILVTLFGNTLVVVSVIKFRRLRSQMCFRFLCSLAISDICVAVFVMFVSMIYFLVQLWPFGWVFCYFWMSCDVMCCTASILHLCAVAIDRYISIAHGLRYATLMTGRRALTIIVAIWLLSVLISFVPIYSNWFGPLNWNGTFHGSCDLD---VNHVYALISSLTSFYIPFLALSVIYFEIYRIASFQAKQIRHQ-------QSRSESKKSKNDRKAIKTVGLIVGLFSLCWFPFFIMYVVRGFCKTCFIDNNWILFITWIGYVNSSFNPILYCFTQRE 294
[Close]
BLAST of GCR129 vs. Planmine SMEST
Match: SMESG000066813.1 (SMESG000066813.1)

HSP 1 Score: 60.8474 bits (146), Expect = 7.950e-10
Identity = 35/129 (27.13%), Postives = 69/129 (53.49%), Query Frame = 2 
Query:  227 ILVVASIIGNVAVIVKLITLGKDFRRNHLIFIFNYAIIEFLLASFVMGVNAAYVISNQWILGNFICSLSCSVNYFCIISSTVTFSLLIIDRYMAICHSLRYNTFVTKSKIQLQILFIWII--GILFSTV 607
            ++ V++I+GN+ VIV      +  R +   FI + A+ + L+  F M     Y++ + W LG   C L  S++Y   ++S  T   + +DR+ ++    +Y  + T+SK++L +   WI+   + F+T+
Sbjct:   32 VVSVSTIMGNLLVIVSFF-FERALRTSTNYFIASLAVTDLLIGVFSMNFYTVYLLLSYWPLGELFCDLWLSLDYTACLTSQYTVFFITVDRFCSVKIPAKYRNWRTESKVRLMVAITWIVPFAVFFTTI 159
[Close]
BLAST of GCR129 vs. Planmine SMEST
Match: SMESG000008878.1 (SMESG000008878.1)

HSP 1 Score: 60.4622 bits (145), Expect = 1.005e-9
Identity = 44/137 (32.12%), Postives = 72/137 (52.55%), Query Frame = 2 
Query:  206 IISGVMLILVVASIIGNVAVIVKLITLGKDFRRNHLIFIFNYAIIEFLLASFVMGVNAAYVISNQWILGNFICSLSCSVNYFCIISSTVTFSLLIIDRYMAICHSLRYNTFVTKSKIQLQILFIWIIGILFSTVPVH 616
            I SGV+++L++ ++IGN  VI  ++ L K+        I + A+ + ++AS VM ++  + IS  W LG  IC L    +  C  +S +    + IDRYMA+     Y    T  +I + I  IW++ I+ S VP  
Sbjct:   32 ITSGVLVVLILCTVIGNSFVIAAIL-LEKNLLNVSNYLIISLAVADLMVASLVMSLSVFHEISEAWFLGLEICDLWVCFDVLCCSASILHLVAIAIDRYMAVTKP-DYVRTRTAKRIYIMIAIIWLLSIMIS-VPTR 165
The following BLAST results are available for this feature:
BLAST of GCR129 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5
Match NameE-valueIdentityDescription
ADRB26.139e-1629.76adrenoceptor beta 2 [Source:HGNC Symbol;Acc:HGNC:2... [more]
ADRA1B1.387e-1230.22adrenoceptor alpha 1B [Source:HGNC Symbol;Acc:HGNC... [more]
ADRB17.145e-1229.73adrenoceptor beta 1 [Source:HGNC Symbol;Acc:HGNC:2... [more]
ADRB33.897e-1126.28adrenoceptor beta 3 [Source:HGNC Symbol;Acc:HGNC:2... [more]
ADRA1A7.028e-1122.17adrenoceptor alpha 1A [Source:HGNC Symbol;Acc:HGNC... [more]
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BLAST of GCR129 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 5
Match NameE-valueIdentityDescription
ser-51.606e-1332.09SERotonin/octopamine receptor family [Source:UniP... [more]
gar-24.394e-1333.33Muscarinic acetylcholine receptor gar-2 [Source:U... [more]
gar-22.517e-1233.33Muscarinic acetylcholine receptor gar-2 [Source:U... [more]
gar-22.940e-1233.33Muscarinic acetylcholine receptor gar-2 [Source:U... [more]
gar-23.213e-1233.33Muscarinic acetylcholine receptor gar-2 [Source:U... [more]
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BLAST of GCR129 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Oct-TyrR3.905e-1129.50gene:FBgn0004514 transcript:FBtr0078479[more]
Oct-TyrR3.905e-1129.50gene:FBgn0004514 transcript:FBtr0301930[more]
5-HT1B9.592e-1125.78gene:FBgn0263116 transcript:FBtr0330055[more]
5-HT1B1.775e-1025.78gene:FBgn0263116 transcript:FBtr0086599[more]
5-HT1B2.049e-1025.78gene:FBgn0263116 transcript:FBtr0330056[more]
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BLAST of GCR129 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
adrb2a3.270e-1825.30adrenoceptor beta 2, surface a [Source:ZFIN;Acc:ZD... [more]
adrb2b6.809e-1725.46adrenoceptor beta 2, surface b [Source:ZFIN;Acc:ZD... [more]
adrb2b7.132e-1725.46adrenoceptor beta 2, surface b [Source:ZFIN;Acc:ZD... [more]
adrb11.781e-1424.09adrenoceptor beta 1 [Source:ZFIN;Acc:ZDB-GENE-0810... [more]
adrb11.781e-1424.09adrenoceptor beta 1 [Source:ZFIN;Acc:ZDB-GENE-0810... [more]
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BLAST of GCR129 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5
Match NameE-valueIdentityDescription
ENSXETT00000011711.11.782e-1527.43adrenoceptor alpha 1B [Source:NCBI gene;Acc:100488... [more]
prrc2c5.838e-1423.57proline-rich coiled-coil 2C [Source:Xenbase;Acc:XB... [more]
ENSXETT00000006856.12.132e-1226.21pep primary_assembly:Xenopus_tropicalis_v9.1:3:118... [more]
ENSXETT00000006865.12.506e-1225.49pep primary_assembly:Xenopus_tropicalis_v9.1:3:118... [more]
efr3b9.488e-1226.62EFR3 homolog B [Source:Xenbase;Acc:XB-GENE-6033491... [more]
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BLAST of GCR129 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Adrb24.089e-1627.95adrenergic receptor, beta 2 [Source:MGI Symbol;Acc... [more]
Adrb31.240e-1328.21adrenergic receptor, beta 3 [Source:MGI Symbol;Acc... [more]
Adrb31.240e-1328.21adrenergic receptor, beta 3 [Source:MGI Symbol;Acc... [more]
Adrb31.296e-1328.21adrenergic receptor, beta 3 [Source:MGI Symbol;Acc... [more]
Hrh27.308e-1330.50histamine receptor H2 [Source:MGI Symbol;Acc:MGI:1... [more]
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BLAST of GCR129 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|P04274|ADRB2_MESAU5.698e-1827.24Beta-2 adrenergic receptor OS=Mesocricetus auratus... [more]
sp|Q8K4Z4|ADRB2_CAVPO1.466e-1626.18Beta-2 adrenergic receptor OS=Cavia porcellus OX=1... [more]
sp|Q28509|ADRB2_MACMU2.968e-1626.28Beta-2 adrenergic receptor OS=Macaca mulatta OX=95... [more]
sp|P54833|ADRB2_CANLF3.705e-1626.60Beta-2 adrenergic receptor OS=Canis lupus familiar... [more]
sp|Q9TST5|ADRB2_FELCA4.286e-1626.28Beta-2 adrenergic receptor OS=Felis catus OX=9685 ... [more]
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BLAST of GCR129 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
A0A193KUE20.000e+0100.00GCR129 OS=Schmidtea mediterranea OX=79327 GN=gcr12... [more]
A0A1S3J8T42.933e-2929.495-hydroxytryptamine receptor 4 OS=Lingula unguis O... [more]
W4Y4591.730e-2428.74G_PROTEIN_RECEP_F1_2 domain-containing protein OS=... [more]
R7UWE74.125e-2325.36G_PROTEIN_RECEP_F1_2 domain-containing protein (Fr... [more]
K1RP616.696e-2129.37Histamine H2 receptor OS=Crassostrea gigas OX=2915... [more]
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BLAST of GCR129 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
adrb2a5.328e-1726.74adrenoceptor beta 2 [Source:NCBI gene;Acc:10304118... [more]
adrb2b1.025e-1531.08beta-2 adrenergic receptor-like [Source:NCBI gene;... [more]
adra1ba9.029e-1425.11adrenoceptor alpha 1B [Source:NCBI gene;Acc:103033... [more]
ENSAMXT00000052904.12.160e-1326.09pep primary_assembly:Astyanax_mexicanus-2.0:21:183... [more]
adra1aa3.857e-1327.01alpha-1A adrenergic receptor-like [Source:NCBI gen... [more]
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BLAST of GCR129 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 5
Match NameE-valueIdentityDescription
HTR1F9.813e-1227.975-hydroxytryptamine receptor 1F [Source:HGNC Symbo... [more]
TAAR12.870e-1125.76trace amine associated receptor 1 [Source:HGNC Sym... [more]
ENSPMAT00000008360.12.661e-1025.78pep scaffold:Pmarinus_7.0:GL477173:168532:170490:1... [more]
oprk17.113e-1031.87opioid receptor, kappa 1 [Source:ZFIN;Acc:ZDB-GENE... [more]
ENSPMAT00000010661.17.558e-1030.25pep scaffold:Pmarinus_7.0:GL479584:296:6514:-1 gen... [more]
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BLAST of GCR129 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of GCR129 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 5
Match NameE-valueIdentityDescription
EDO317166.299e-1524.15Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO393529.929e-1425.27Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO370581.512e-1219.75Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO352451.263e-1124.50Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO383422.735e-1124.45Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
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BLAST of GCR129 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5
Match NameE-valueIdentityDescription
ENSORLT00000006865.21.085e-1424.00alpha-1A adrenergic receptor [Source:NCBI gene;Acc... [more]
adra1aa1.155e-1423.04alpha-1A adrenergic receptor [Source:NCBI gene;Acc... [more]
ENSORLT00000002753.21.474e-1430.67beta-2 adrenergic receptor [Source:NCBI gene;Acc:1... [more]
adrb15.782e-1423.66adrenoceptor beta 1 [Source:ZFIN;Acc:ZDB-GENE-0810... [more]
adrb3a8.557e-1426.12adrenoceptor beta 3a [Source:ZFIN;Acc:ZDB-GENE-080... [more]
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BLAST of GCR129 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5
Match NameE-valueIdentityDescription
SMESG000059005.10.000e+0100.00SMESG000059005.1[more]
SMESG000055001.16.768e-1429.93SMESG000055001.1[more]
SMESG000023113.11.559e-1323.26SMESG000023113.1[more]
SMESG000066813.17.950e-1027.13SMESG000066813.1[more]
SMESG000008878.11.005e-932.12SMESG000008878.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30014227 ID=SMED30014227|Name=GCR129|organism=Schmidtea mediterranea sexual|type=transcript|length=1188bp
CGATCTCTCAAATTAATTACGACTTATATTGGAAAATCAAAGTATCCGTT
AAATAAGTCAATGATAGAATCCAAGACAGATAAAAGAAACAAGTGTAAAG
CAAGTGGAAATTTGGCAGTTATATGAATTATTTTGGATCTTTGTATATTT
GAGAAGAAAATTATTAGAAAACTGAGTAAGCATGAGAACAACAGCTGAAA
GGGTCATTATATCCGGTGTCATGCTAATACTTGTTGTAGCATCCATTATC
GGGAATGTCGCCGTCATTGTCAAACTTATAACTCTAGGAAAAGATTTTCG
AAGAAATCATTTAATTTTCATTTTTAATTACGCAATCATAGAATTCCTGC
TGGCCTCCTTTGTGATGGGAGTAAATGCTGCATATGTTATATCAAATCAG
TGGATCTTAGGCAACTTCATATGCAGTCTCAGTTGTTCCGTGAATTACTT
TTGCATTATATCTTCCACCGTTACATTTTCTTTACTCATCATTGACCGGT
ACATGGCGATTTGCCATTCGCTGCGCTATAACACTTTTGTCACTAAATCA
AAAATTCAATTACAGATACTTTTTATCTGGATCATTGGCATTTTATTCAG
TACAGTTCCTGTGCATCAAAAAGCTATAATTACTAGTTATTATGAGCTCG
GATGTGCAGTCGATTGGTTGGCTGCGTCCAGTTTTATTATAGTTTTTGTG
ACTTTTACGTTTGTGTTGTTTTTTGCAATTCCCTTGTTCGTCATCATGTA
TTGTTACTATAGAATAATTTCCAAAATTAAAGAAATTTCCCAAACTTTTC
AATCTCCTAATGTAATCCCTTCGAATACAATTTCAGAAAGAATTTCAAGT
GATCAGAAAGTCATAAGAAGCCATGAAATATTGCTCTTTGCAATCGTCAT
GAGCATAGGTCCATATTGGATTTCTAAGATTTTGAAAATGAGTCAAGATC
AAGAATTTGGTCCAAATTATTTAACTACTGCTGGATCTCTGGTGCCGTTA
ATTGGGAGTCTTATTACACCTTTAATATATGTGAATATGCAAACAGAGAT
TTGTGTAGTAACTGAAGTTGAAGATGGAATAAATGTGTAATTATTTTTAG
TAAATATCATCTTTTCTTTCGCTATTAAAACCACCTCAATCTATATTGAC
CCAATTACTTGCAATGCCTTGATTCAGAGATCGGAAGA
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protein sequence of SMED30014227-orf-1

>SMED30014227-orf-1 ID=SMED30014227-orf-1|Name=SMED30014227-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=303bp
MRTTAERVIISGVMLILVVASIIGNVAVIVKLITLGKDFRRNHLIFIFNY
AIIEFLLASFVMGVNAAYVISNQWILGNFICSLSCSVNYFCIISSTVTFS
LLIIDRYMAICHSLRYNTFVTKSKIQLQILFIWIIGILFSTVPVHQKAII
TSYYELGCAVDWLAASSFIIVFVTFTFVLFFAIPLFVIMYCYYRIISKIK
EISQTFQSPNVIPSNTISERISSDQKVIRSHEILLFAIVMSIGPYWISKI
LKMSQDQEFGPNYLTTAGSLVPLIGSLITPLIYVNMQTEICVVTEVEDGI
NV*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000208testis
Vocabulary: INTERPRO
TermDefinition
IPR000276GPCR_Rhodpsn
IPR017452GPCR_Rhodpsn_7TM
Vocabulary: biological process
TermDefinition
GO:0007186G-protein coupled receptor signaling pathway
GO:0002032desensitization of G-protein coupled receptor protein signaling pathway by arrestin
GO:0006898receptor-mediated endocytosis
GO:0006940regulation of smooth muscle contraction
GO:0007165signal transduction
GO:0007189adenylate cyclase-activating G-protein coupled receptor signaling pathway
GO:0007190activation of adenylate cyclase activity
GO:0043410positive regulation of MAPK cascade
GO:0071875adrenergic receptor signaling pathway
GO:1901098positive regulation of autophagosome maturation
GO:1904504positive regulation of lipophagy
Vocabulary: cellular component
TermDefinition
GO:0016021integral component of membrane
GO:0005768endosome
GO:0005769early endosome
GO:0005886plasma membrane
GO:0016020membrane
GO:0043235receptor complex
Vocabulary: molecular function
TermDefinition
GO:0004930G-protein coupled receptor activity
GO:0004871signal transducer activity
GO:0004935adrenergic receptor activity
GO:0004941beta2-adrenergic receptor activity
GO:0042803protein homodimerization activity
GO:0051380norepinephrine binding
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR000276G protein-coupled receptor, rhodopsin-likePRINTSPR00237GPCRRHODOPSNcoord: 88..110
score: 26.17
coord: 124..145
score: 18.63
coord: 265..291
score: 17.45
coord: 43..64
score: 20.29
coord: 173..196
score: 29.74
coord: 9..33
score: 23.29
IPR000276G protein-coupled receptor, rhodopsin-likePFAMPF000017tm_1coord: 24..283
e-value: 5.0E-33
score: 114.6
NoneNo IPR availableGENE3DG3DSA:1.20.1070.10coord: 2..293
e-value: 2.9E-45
score: 156.5
NoneNo IPR availablePANTHERPTHR24229NEUROPEPTIDES RECEPTORcoord: 5..285
NoneNo IPR availableCDDcd006377tm_classA_rhodopsin-likecoord: 10..283
e-value: 3.67269E-29
score: 110.445
NoneNo IPR availableSUPERFAMILYSSF81321Family A G protein-coupled receptor-likecoord: 6..288
NoneNo IPR availableTMHMMTMhelixcoord: 262..284
NoneNo IPR availableTMHMMTMhelixcoord: 45..67
NoneNo IPR availableTMHMMTMhelixcoord: 125..144
NoneNo IPR availableTMHMMTMhelixcoord: 230..247
NoneNo IPR availableTMHMMTMhelixcoord: 168..190
NoneNo IPR availableTMHMMTMhelixcoord: 82..104
NoneNo IPR availableTMHMMTMhelixcoord: 10..32
IPR017452GPCR, rhodopsin-like, 7TMPROSITEPS50262G_PROTEIN_RECEP_F1_2coord: 24..283
score: 32.95