AGO-2

Overview


Name	AGO-2 (ADY05336.1)
Smed ID	SMED30014222
Length (bp)	3040

Neoblast Clusters

Overview

Single cell RNA-seq of pluripotent neoblasts and its early progenies

We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)

Explore this single cell expression dataset with our NB Cluster Shiny App

Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

Anatomical Expression

PAGE et. al., 2020

SMED30014222

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE

PAGE Curations: 1

Expressed In	Reference Transcript	Gene Models	Published Transcript	Transcriptome	Publication	Specimen	Lifecycle	Evidence
whole organism	SMED30014222		JF263459	smed_ncbi_20240424	PMID:21894189 Li et al., 2011

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Homology

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BLAST of AGO-2 vs. Ensembl Human
Match: AGO2 (argonaute RISC catalytic component 2 [Source:HGNC Symbol;Acc:HGNC:3263])

HSP 1 Score: 1307.35 bits (3382), Expect = 0.000e+0
Identity = 619/838 (73.87%), Postives = 714/838 (85.20%), Query Frame = 1

Query:  277 FQPPSRPDQGTDGRTIQLKANHFEIVMPKGFLHHYDITITPEKCPRRVNRDIIQAMVNNMHYQKYFYNQKPVFDGRRNMYTREPLSIGKEKLELEVILPGEGKDRVFKVCLKHVSEVSLFALEEALQGRRQTIPAETVTALDVIMRHLPSMTYTPVGRSFFHNTGDYDNPLGGGREVWFGFHQSVRPSQWKMMLNIDVSATAFYKEQSVINFMFEVLEID--KDLKRPLTDSQRVKFTKEIKGLKVEINHCGPIKRKYRVCNVTRRSAQSQTFPLQSEQGQTIECTVTKYFQDRYGMKLQHPHLPCLQVGQEQKHTYLPLEVCNIVSGQRCIKKLTDMQTSTMIKATARSAPDREKEINNLVRRSNFNADPHLQIFGVSVNTRMADIQGRVIPAPKIQYGGRTKAQATPQQGVWDMRGKQFFSGIEIKVWAIACFAPQRTVREDSLRTFTQQLQKISNDAGMPIVGQPCFCKYATGQDQVEPMFRYLKNSFSGLQLIVVVLPGKTPVYAEVKRVGDIIFGLATQCVQAKNVNKPSPQTLSNLCLKINVKLGGINSILVPSVRPAVFKEPVIFLGADFTHPPAGDKTKPSIAAVVGSMDAHPSRYAATVSVQPHRQETIQDLAAMVKELLIQFYKSTRFKPTRIIYYRDGVSEGQFLNVLNHELKAIREACIKLEMSYQPGITFVVVQKRHHTRLFCSDKKDQMGRSGNIPAGTTVDQIITHPTEFDFYLCSHAGIQGTSRPSHYHVLWDDNRFSADEIQTLTYQLCHTYVRCTRSVSIPAPAYYAHLVAFRARYHLVEKELDSGEGSQKSGNSDERNPTAMMRAVTVHSETLKVMYFA 2784
            F+PP RPD GT GRTI+L+AN FE+ +PK  ++HY++ I PEKCPRRVNR+I++ MV +   Q  F ++KPVFDGR+N+YT  PL IG++K+ELEV LPGEGKDR+FKV +K VS VSL AL +AL GR  ++P ET+ ALDV+MRHLPSM YTPVGRSFF  +    NPLGGGREVWFGFHQSVRPS WKMMLNIDVSATAFYK Q VI F+ EVL+    ++ ++PLTDSQRVKFTKEIKGLKVEI HCG +KRKYRVCNVTRR A  QTFPLQ E GQT+ECTV +YF+DR+ + L++PHLPCLQVGQEQKHTYLPLEVCNIV+GQRCIKKLTD QTSTMI+ATARSAPDR++EI+ L+R ++FN DP+++ FG+ V   M D+ GRV+  P I YGGR KA ATP QGVWDMR KQF +GIEIKVWAIACFAPQR   E  L++FT+QL+KIS DAGMPI GQPCFCKYA G D VEPMFR+LKN+++GLQL+VV+LPGKTPVYAEVKRVGD + G+ATQCVQ KNV + +PQTLSNLCLKINVKLGG+N+IL+P  RP VF++PVIFLGAD THPPAGD  KPSIAAVVGSMDAHP+RY ATV VQ HRQE IQDLAAMV+ELLIQFYKSTRFKPTRII+YRDGVSEGQF  VL+HEL AIREACIKLE  YQPGITF+VVQKRHHTRLFC+DK +++G+SGNIPAGTTVD  ITHPTEFDFYLCSHAGIQGTSRPSHYHVLWDDNRFS+DE+Q LTYQLCHTYVRCTRSVSIPAPAYYAHLVAFRARYHLV+KE DS EGS  SG S+ R+  A+ +AV VH +TL+ MYFA
Sbjct:   23 FKPPPRPDFGTSGRTIKLQANFFEMDIPKIDIYHYELDIKPEKCPRRVNREIVEHMVQHFKTQ-IFGDRKPVFDGRKNLYTAMPLPIGRDKVELEVTLPGEGKDRIFKVSIKWVSCVSLQALHDALSGRLPSVPFETIQALDVVMRHLPSMRYTPVGRSFFTASEGCSNPLGGGREVWFGFHQSVRPSLWKMMLNIDVSATAFYKAQPVIEFVCEVLDFKSIEEQQKPLTDSQRVKFTKEIKGLKVEITHCGQMKRKYRVCNVTRRPASHQTFPLQQESGQTVECTVAQYFKDRHKLVLRYPHLPCLQVGQEQKHTYLPLEVCNIVAGQRCIKKLTDNQTSTMIRATARSAPDRQEEISKLMRSASFNTDPYVREFGIMVKDEMTDVTGRVLQPPSILYGGRNKAIATPVQGVWDMRNKQFHTGIEIKVWAIACFAPQRQCTEVHLKSFTEQLRKISRDAGMPIQGQPCFCKYAQGADSVEPMFRHLKNTYAGLQLVVVILPGKTPVYAEVKRVGDTVLGMATQCVQMKNVQRTTPQTLSNLCLKINVKLGGVNNILLPQGRPPVFQQPVIFLGADVTHPPAGDGKKPSIAAVVGSMDAHPNRYCATVRVQQHRQEIIQDLAAMVRELLIQFYKSTRFKPTRIIFYRDGVSEGQFQQVLHHELLAIREACIKLEKDYQPGITFIVVQKRHHTRLFCTDKNERVGKSGNIPAGTTVDTKITHPTEFDFYLCSHAGIQGTSRPSHYHVLWDDNRFSSDELQILTYQLCHTYVRCTRSVSIPAPAYYAHLVAFRARYHLVDKEHDSAEGSHTSGQSNGRDHQALAKAVQVHQDTLRTMYFA 859

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BLAST of AGO-2 vs. Ensembl Human
Match: AGO1 (argonaute RISC component 1 [Source:HGNC Symbol;Acc:HGNC:3262])

HSP 1 Score: 1256.89 bits (3251), Expect = 0.000e+0
Identity = 595/838 (71.00%), Postives = 701/838 (83.65%), Query Frame = 1

Query:  277 FQPPSRPDQGTDGRTIQLKANHFEIVMPKGFLHHYDITITPEKCPRRVNRDIIQAMVNNMHYQKYFYNQKPVFDGRRNMYTREPLSIGKEKLELEVILPGEGKDRVFKVCLKHVSEVSLFALEEALQGRRQTIPAETVTALDVIMRHLPSMTYTPVGRSFFHNTGDYDNPLGGGREVWFGFHQSVRPSQWKMMLNIDVSATAFYKEQSVINFMFEVLEIDK--DLKRPLTDSQRVKFTKEIKGLKVEINHCGPIKRKYRVCNVTRRSAQSQTFPLQSEQGQTIECTVTKYFQDRYGMKLQHPHLPCLQVGQEQKHTYLPLEVCNIVSGQRCIKKLTDMQTSTMIKATARSAPDREKEINNLVRRSNFNADPHLQIFGVSVNTRMADIQGRVIPAPKIQYGGRTKAQATPQQGVWDMRGKQFFSGIEIKVWAIACFAPQRTVREDSLRTFTQQLQKISNDAGMPIVGQPCFCKYATGQDQVEPMFRYLKNSFSGLQLIVVVLPGKTPVYAEVKRVGDIIFGLATQCVQAKNVNKPSPQTLSNLCLKINVKLGGINSILVPSVRPAVFKEPVIFLGADFTHPPAGDKTKPSIAAVVGSMDAHPSRYAATVSVQPHRQETIQDLAAMVKELLIQFYKSTRFKPTRIIYYRDGVSEGQFLNVLNHELKAIREACIKLEMSYQPGITFVVVQKRHHTRLFCSDKKDQMGRSGNIPAGTTVDQIITHPTEFDFYLCSHAGIQGTSRPSHYHVLWDDNRFSADEIQTLTYQLCHTYVRCTRSVSIPAPAYYAHLVAFRARYHLVEKELDSGEGSQKSGNSDERNPTAMMRAVTVHSETLKVMYFA 2784
            FQ P RP  GT G+ I+L AN+FE+ +PK  ++HY++ I P+KCPRRVNR++++ MV +   Q  F ++KPV+DG++N+YT   L IG E+++ EV +PGEGKDR+FKV +K ++ VS   L EAL   +  +P E+V ALDV MRHL SM YTPVGRSFF     Y +PLGGGREVWFGFHQSVRP+ WKMMLNIDVSATAFYK Q VI FM EVL+I    +  +PLTDSQRV+FTKEIKGLKVE+ HCG +KRKYRVCNVTRR A  QTFPLQ E GQT+ECTV +YF+ +Y ++L++PHLPCLQVGQEQKHTYLPLEVCNIV+GQRCIKKLTD QTSTMIKATARSAPDR++EI+ L++ +++N DP++Q FG+ V   M ++ GRV+PAP +QYGGR +A ATP QGVWDMRGKQF++GIEIKVWAIACFAPQ+  RE+ L+ FT QL+KIS DAGMPI GQPCFCKYA G D VEPMFR+LKN++SGLQLI+V+LPGKTPVYAEVKRVGD + G+ATQCVQ KNV K SPQTLSNLCLKINVKLGGIN+ILVP  R AVF++PVIFLGAD THPPAGD  KPSI AVVGSMDAHPSRY ATV VQ  RQE I+DL+ MV+ELLIQFYKSTRFKPTRII+YRDGV EGQ   +L++EL AIR+ACIKLE  YQPGIT++VVQKRHHTRLFC+DK +++G+SGNIPAGTTVD  ITHP EFDFYLCSHAGIQGTSRPSHY+VLWDDNRF+ADE+Q LTYQLCHTYVRCTRSVSIPAPAYYA LVAFRARYHLV+KE DSGEGS  SG S+ R+P A+ +AV VH +TL+ MYFA
Sbjct:   21 FQAPRRPGIGTVGKPIKLLANYFEVDIPKIDVYHYEVDIKPDKCPRRVNREVVEYMVQHFKPQ-IFGDRKPVYDGKKNIYTVTALPIGNERVDFEVTIPGEGKDRIFKVSIKWLAIVSWRMLHEALVSGQIPVPLESVQALDVAMRHLASMRYTPVGRSFFSPPEGYYHPLGGGREVWFGFHQSVRPAMWKMMLNIDVSATAFYKAQPVIEFMCEVLDIRNIDEQPKPLTDSQRVRFTKEIKGLKVEVTHCGQMKRKYRVCNVTRRPASHQTFPLQLESGQTVECTVAQYFKQKYNLQLKYPHLPCLQVGQEQKHTYLPLEVCNIVAGQRCIKKLTDNQTSTMIKATARSAPDRQEEISRLMKNASYNLDPYIQEFGIKVKDDMTEVTGRVLPAPILQYGGRNRAIATPNQGVWDMRGKQFYNGIEIKVWAIACFAPQKQCREEVLKNFTDQLRKISKDAGMPIQGQPCFCKYAQGADSVEPMFRHLKNTYSGLQLIIVILPGKTPVYAEVKRVGDTLLGMATQCVQVKNVVKTSPQTLSNLCLKINVKLGGINNILVPHQRSAVFQQPVIFLGADVTHPPAGDGKKPSITAVVGSMDAHPSRYCATVRVQRPRQEIIEDLSYMVRELLIQFYKSTRFKPTRIIFYRDGVPEGQLPQILHYELLAIRDACIKLEKDYQPGITYIVVQKRHHTRLFCADKNERIGKSGNIPAGTTVDTNITHPFEFDFYLCSHAGIQGTSRPSHYYVLWDDNRFTADELQILTYQLCHTYVRCTRSVSIPAPAYYARLVAFRARYHLVDKEHDSGEGSHISGQSNGRDPQALAKAVQVHQDTLRTMYFA 857

[Close]

BLAST of AGO-2 vs. Ensembl Human
Match: AGO3 (argonaute RISC catalytic component 3 [Source:HGNC Symbol;Acc:HGNC:18421])

HSP 1 Score: 1233.01 bits (3189), Expect = 0.000e+0
Identity = 593/844 (70.26%), Postives = 688/844 (81.52%), Query Frame = 1

Query:  286 PSRPDQGTDGRTIQLKANHFEIVMPKGFLHHYDITITPEKCPRRVNRDIIQAMVNNMHYQKYFYNQKPVFDGRRNMYTREPLSIGKEKLELEVILPGEG-KDRVFKVCLKHVSEVSLFALEEALQGRRQTIPAET--------VTALDVIMRHLPSMTYTPVGRSFFHNTGDYDNPLGGGREVWFGFHQSVRPSQWKMMLNIDVSATAFYKEQSVINFMFEVLEIDK--DLKRPLTDSQRVKFTKEIKGLKVEINHCGPIKRKYRVCNVTRRSAQSQTFPLQSEQGQTIECTVTKYFQDRYGMKLQHPHLPCLQVGQEQKHTYLPLEVCNIVSGQRCIKKLTDMQTSTMIKATARSAPDREKEINNLVRRSNFNADPHLQIFGVSVNTRMADIQGRVIPAPKIQYGGRTKAQATPQQGVWDMRGKQFFSGIEIKVWAIACFAPQRTVREDSLRTFTQQLQKISNDAGMPIVGQPCFCKYATGQDQVEPMFRYLKNSFSGLQLIVVVLPGKTPVYAEVKRVGDIIFGLATQCVQAKNVNKPSPQTLSNLCLKINVKLGGINSILVPSVRPAVFKEPVIFLGADFTHPPAGDKTKPSIAAVVGSMDAHPSRYAATVSVQPHRQETIQDLAAMVKELLIQFYKSTRFKPTRIIYYRDGVSEGQFLNVLNHELKAIREACIKLEMSYQPGITFVVVQKRHHTRLFCSDKKDQMGRSGNIPAGTTVDQIITHPTEFDFYLCSHAGIQGTSRPSHYHVLWDDNRFSADEIQTLTYQLCHTYVRCTRSVSIPAPAYYAHLVAFRARYHLVEKELDSGEGSQKSGNSDERNPTAMMRAVTVHSETLKVMYFA 2784
            P RP  GT G+ I+L AN F++ +PK  ++ Y++ I P+KCPRRVNR+++ +MV +      F +++PV+DG+R++YT  PL +    ++L+V LPGEG KDR FKV +K VS VS   L E L GR    P E         V A+DV++RHLPSM YTPVGRSFF     YD+PLGGGREVWFGFHQSVRP+ WKMMLNIDVSATAFYK Q VI FM EVL+I    +  RPLTDS RVKFTKEIKGLKVE+ HCG ++RKYRVCNVTRR A  QTFPLQ E GQT+E TV +YF+++Y ++L++PHLPCLQVGQEQKHTYLPLEVCNIV+GQRCIKKLTD QTSTMIKATARSAPDR++EI+ LVR +N+  DP +Q F   V   MA + GRV+PAP +QYGGR +  ATP  GVWDMRGKQF +G+EIK+WAIACFA QR  RE+ L+ FT QL+KIS DAGMPI GQPCFCKYA G D VEPMFR+LKN++SGLQLI+V+LPGKTPVYAEVKRVGD + G+ATQCVQ KNV K SPQTLSNLCLKINVKLGGIN+ILVP  RP+VF++PVIFLGAD THPPAGD  KPSIAAVVGSMDAHPSRY ATV VQ  RQE IQDLA+MV+ELLIQFYKSTRFKPTRII+YRDGVSEGQF  VL +EL AIREACI LE  YQPGIT++VVQKRHHTRLFC+D+ +++GRSGNIPAGTTVD  ITHP EFDFYLCSHAGIQGTSRPSHYHVLWDDN F+ADE+Q LTYQLCHTYVRCTRSVSIPAPAYYAHLVAFRARYHLV+KE DS EGS  SG S+ R+P A+ +AV +H +TL+ MYFA
Sbjct:   18 PRRPGYGTMGKPIKLLANCFQVEIPKIDVYLYEVDIKPDKCPRRVNREVVDSMVQHFKV-TIFGDRRPVYDGKRSLYTANPLPVATTGVDLDVTLPGEGGKDRPFKVSIKFVSRVSWHLLHEVLTGRTLPEPLELDKPISTNPVHAVDVVLRHLPSMKYTPVGRSFFSAPEGYDHPLGGGREVWFGFHQSVRPAMWKMMLNIDVSATAFYKAQPVIQFMCEVLDIHNIDEQPRPLTDSHRVKFTKEIKGLKVEVTHCGTMRRKYRVCNVTRRPASHQTFPLQLENGQTVERTVAQYFREKYTLQLKYPHLPCLQVGQEQKHTYLPLEVCNIVAGQRCIKKLTDNQTSTMIKATARSAPDRQEEISRLVRSANYETDPFVQEFQFKVRDEMAHVTGRVLPAPMLQYGGRNRTVATPSHGVWDMRGKQFHTGVEIKMWAIACFATQRQCREEILKGFTDQLRKISKDAGMPIQGQPCFCKYAQGADSVEPMFRHLKNTYSGLQLIIVILPGKTPVYAEVKRVGDTLLGMATQCVQVKNVIKTSPQTLSNLCLKINVKLGGINNILVPHQRPSVFQQPVIFLGADVTHPPAGDGKKPSIAAVVGSMDAHPSRYCATVRVQRPRQEIIQDLASMVRELLIQFYKSTRFKPTRIIFYRDGVSEGQFRQVLYYELLAIREACISLEKDYQPGITYIVVQKRHHTRLFCADRTERVGRSGNIPAGTTVDTDITHPYEFDFYLCSHAGIQGTSRPSHYHVLWDDNCFTADELQLLTYQLCHTYVRCTRSVSIPAPAYYAHLVAFRARYHLVDKEHDSAEGSHVSGQSNGRDPQALAKAVQIHQDTLRTMYFA 860

[Close]

BLAST of AGO-2 vs. Ensembl Human
Match: AGO2 (argonaute RISC catalytic component 2 [Source:HGNC Symbol;Acc:HGNC:3263])

HSP 1 Score: 1225.31 bits (3169), Expect = 0.000e+0
Identity = 589/838 (70.29%), Postives = 682/838 (81.38%), Query Frame = 1

Query:  277 FQPPSRPDQGTDGRTIQLKANHFEIVMPKGFLHHYDITITPEKCPRRVNRDIIQAMVNNMHYQKYFYNQKPVFDGRRNMYTREPLSIGKEKLELEVILPGEGKDRVFKVCLKHVSEVSLFALEEALQGRRQTIPAETVTALDVIMRHLPSMTYTPVGRSFFHNTGDYDNPLGGGREVWFGFHQSVRPSQWKMMLNIDVSATAFYKEQSVINFMFEVLEID--KDLKRPLTDSQRVKFTKEIKGLKVEINHCGPIKRKYRVCNVTRRSAQSQTFPLQSEQGQTIECTVTKYFQDRYGMKLQHPHLPCLQVGQEQKHTYLPLEVCNIVSGQRCIKKLTDMQTSTMIKATARSAPDREKEINNLVRRSNFNADPHLQIFGVSVNTRMADIQGRVIPAPKIQYGGRTKAQATPQQGVWDMRGKQFFSGIEIKVWAIACFAPQRTVREDSLRTFTQQLQKISNDAGMPIVGQPCFCKYATGQDQVEPMFRYLKNSFSGLQLIVVVLPGKTPVYAEVKRVGDIIFGLATQCVQAKNVNKPSPQTLSNLCLKINVKLGGINSILVPSVRPAVFKEPVIFLGADFTHPPAGDKTKPSIAAVVGSMDAHPSRYAATVSVQPHRQETIQDLAAMVKELLIQFYKSTRFKPTRIIYYRDGVSEGQFLNVLNHELKAIREACIKLEMSYQPGITFVVVQKRHHTRLFCSDKKDQMGRSGNIPAGTTVDQIITHPTEFDFYLCSHAGIQGTSRPSHYHVLWDDNRFSADEIQTLTYQLCHTYVRCTRSVSIPAPAYYAHLVAFRARYHLVEKELDSGEGSQKSGNSDERNPTAMMRAVTVHSETLKVMYFA 2784
            F+PP RPD GT GRTI+L+AN FE+ +PK  ++HY++ I PEKCPRRVNR+I++ MV +   Q  F ++KPVFDGR+N+YT  PL IG++K+ELEV LPGEGKDR+FKV +K VS VSL AL +AL GR  ++P ET+ ALDV+MRHLPSM YTPVGRSFF  +    NPLGGGREVWFGFHQSVRPS WKMMLNIDVSATAFYK Q VI F+ EVL+    ++ ++PLTDSQRVKFTKEIKGLKVEI HCG +KRKYRVCNVTRR A  QTFPLQ E GQT+ECTV +YF+DR+ + L++PHLPCLQVGQEQKHTYLPLEVCNIV+GQRCIKKLTD QTSTMI+ATARSAPDR++EI+ L+R ++FN DP+++ FG+ V   M D+ GRV+  P I YGGR KA ATP QGVWDMR KQF +GIEIKVWAIACFAPQR   E  L++FT+QL+KIS DAGMPI GQPCFCKYA G D VEPMFR+LKN+++GLQL+VV+LPGKTPVYAEVKRVGD + G+ATQCVQ KNV + +PQTLSNLCLKINVKLGG+N+IL+P  RP VF++PVIFLGAD THPPAGD  KPSIAAVVGSMDAHP+RY ATV VQ HRQE IQDLAAMV+ELLIQFYKSTRFKPTRII+YRDGVSEGQF  VL+HEL AIREACIKLE  YQPGITF+VVQKRHHTRLFC+DK +                                  +GTSRPSHYHVLWDDNRFS+DE+Q LTYQLCHTYVRCTRSVSIPAPAYYAHLVAFRARYHLV+KE DS EGS  SG S+ R+  A+ +AV VH +TL+ MYFA
Sbjct:   23 FKPPPRPDFGTSGRTIKLQANFFEMDIPKIDIYHYELDIKPEKCPRRVNREIVEHMVQHFKTQ-IFGDRKPVFDGRKNLYTAMPLPIGRDKVELEVTLPGEGKDRIFKVSIKWVSCVSLQALHDALSGRLPSVPFETIQALDVVMRHLPSMRYTPVGRSFFTASEGCSNPLGGGREVWFGFHQSVRPSLWKMMLNIDVSATAFYKAQPVIEFVCEVLDFKSIEEQQKPLTDSQRVKFTKEIKGLKVEITHCGQMKRKYRVCNVTRRPASHQTFPLQQESGQTVECTVAQYFKDRHKLVLRYPHLPCLQVGQEQKHTYLPLEVCNIVAGQRCIKKLTDNQTSTMIRATARSAPDRQEEISKLMRSASFNTDPYVREFGIMVKDEMTDVTGRVLQPPSILYGGRNKAIATPVQGVWDMRNKQFHTGIEIKVWAIACFAPQRQCTEVHLKSFTEQLRKISRDAGMPIQGQPCFCKYAQGADSVEPMFRHLKNTYAGLQLVVVILPGKTPVYAEVKRVGDTVLGMATQCVQMKNVQRTTPQTLSNLCLKINVKLGGVNNILLPQGRPPVFQQPVIFLGADVTHPPAGDGKKPSIAAVVGSMDAHPNRYCATVRVQQHRQEIIQDLAAMVRELLIQFYKSTRFKPTRIIFYRDGVSEGQFQQVLHHELLAIREACIKLEKDYQPGITFIVVQKRHHTRLFCTDKNE----------------------------------RGTSRPSHYHVLWDDNRFSSDELQILTYQLCHTYVRCTRSVSIPAPAYYAHLVAFRARYHLVDKEHDSAEGSHTSGQSNGRDHQALAKAVQVHQDTLRTMYFA 825

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BLAST of AGO-2 vs. Ensembl Human
Match: AGO4 (argonaute RISC component 4 [Source:HGNC Symbol;Acc:HGNC:18424])

HSP 1 Score: 1217.99 bits (3150), Expect = 0.000e+0
Identity = 586/850 (68.94%), Postives = 689/850 (81.06%), Query Frame = 1

Query:  277 FQPPSRPDQGTDGRTIQLKANHFEIVMPKGFLHHYDITITPEKCPRRVNRDIIQAMVNNMHYQKYFYNQKPVFDGRRNMYTREPLSIGKEKLELEVILPGEGKDRVFKVCLKHVSEVSLFALEEALQGRRQTIPAETVTALDVIMRHLPSMTYTPVGRSFFHNTGDYDNPLGGGREVWFGFHQSVRPSQWKMMLNIDVSATAFYKEQSVINFMFEVLEIDK--DLKRPLTDSQRVKFTKEIKGLKVEINHCGPIKRKYRVCNVTRRSAQSQTFPLQSEQGQTIECTVTKYFQDRYGMKLQHPHLPCLQVGQEQKHTYLPLEVCNIVSGQRCIKKLTDMQTSTMIKATARSAPDREKEINNLVRRSNF--NADPHLQIFGVSVNTRMADIQGRVIPAPKIQYGGRTKAQATPQQGVWDMRGKQFFSGIEIKVWAIACFAPQRTVREDSLRTFTQQLQKISNDAGMPIVGQPCFCKYATGQDQVEPMFRYLKNSFSGLQLIVVVLPGKTPVYAEVKRVGDIIFGLATQCVQAKNVNKPSPQTLSNLCLKINVKLGGINSILVPSVRPAVFKEPVIFLGADFTHPPAGDKTKPSIAAVVGSMDAHPSRYAATVSVQPHR----------QETIQDLAAMVKELLIQFYKSTRFKPTRIIYYRDGVSEGQFLNVLNHELKAIREACIKLEMSYQPGITFVVVQKRHHTRLFCSDKKDQMGRSGNIPAGTTVDQIITHPTEFDFYLCSHAGIQGTSRPSHYHVLWDDNRFSADEIQTLTYQLCHTYVRCTRSVSIPAPAYYAHLVAFRARYHLVEKELDSGEGSQKSGNSDERNPTAMMRAVTVHSETLKVMYFA 2784
            FQPP RP  GT G+ I+L ANHF++ +PK  ++HYD+ I PEK PRRVNR+++  MV +   Q  F +++P +DG+RNMYT  PL IG++++++EV LPGEGKD+ FKV ++ VS VSL  L EAL G    +P ++V ALDVI RHLPSM YTPVGRSFF     Y +PLGGGREVWFGFHQSVRP+ W MMLNIDVSATAFY+ Q +I FM EVL+I    +  +PLTDSQRVKFTKEI+GLKVE+ HCG +KRKYRVCNVTRR A  QTFPLQ E GQ +ECTV +YF+ +Y ++L++PHLPCLQVGQEQKHTYLPLEVCNIV+GQRCIKKLTD QTSTMIKATARSAPDR++EI+ LV+ ++     DP+L+ FG+ V+  M ++ GRV+PAP +QYGGR K  ATP QGVWDMRGKQF++GIEIKVWA+ACFAPQ+  RED L++FT QL+KIS DAGMPI GQPCFCKYA G D VEPMF++LK ++ GLQLIVV+LPGKTPVYAEVKRVGD + G+ATQCVQ KNV K SPQTLSNLCLKIN KLGGIN++LVP  RP+VF++PVIFLGAD THPPAGD  KPSIAAVVGSMD HPSRY ATV VQ  R          QE IQDL  MV+ELLIQFYKSTRFKPTRIIYYR GVSEGQ   V   EL AIR+ACI LE  Y+PGIT++VVQKRHHTRLFC+DK +++G+SGN+PAGTTVD  ITHP+EFDFYLCSHAGIQGTSRPSHY VLWDDN F+ADE+Q LTYQLCHTYVRCTRSVSIPAPAYYA LVAFRARYHLV+K+ DS EGS  SG S+ R+P A+ +AV +H +T   MYFA
Sbjct:   13 FQPPRRPGLGTVGKPIRLLANHFQVQIPKIDVYHYDVDIKPEKRPRRVNREVVDTMVRHFKMQ-IFGDRQPGYDGKRNMYTAHPLPIGRDRVDMEVTLPGEGKDQTFKVSVQWVSVVSLQLLLEALAGHLNEVPDDSVQALDVITRHLPSMRYTPVGRSFFSPPEGYYHPLGGGREVWFGFHQSVRPAMWNMMLNIDVSATAFYRAQPIIEFMCEVLDIQNINEQTKPLTDSQRVKFTKEIRGLKVEVTHCGQMKRKYRVCNVTRRPASHQTFPLQLENGQAMECTVAQYFKQKYSLQLKYPHLPCLQVGQEQKHTYLPLEVCNIVAGQRCIKKLTDNQTSTMIKATARSAPDRQEEISRLVKSNSMVGGPDPYLKEFGIVVHNEMTELTGRVLPAPMLQYGGRNKTVATPNQGVWDMRGKQFYAGIEIKVWAVACFAPQKQCREDLLKSFTDQLRKISKDAGMPIQGQPCFCKYAQGADSVEPMFKHLKMTYVGLQLIVVILPGKTPVYAEVKRVGDTLLGMATQCVQVKNVVKTSPQTLSNLCLKINAKLGGINNVLVPHQRPSVFQQPVIFLGADVTHPPAGDGKKPSIAAVVGSMDGHPSRYCATVRVQTSRQEISQELLYSQEVIQDLTNMVRELLIQFYKSTRFKPTRIIYYRGGVSEGQMKQVAWPELIAIRKACISLEEDYRPGITYIVVQKRHHTRLFCADKTERVGKSGNVPAGTTVDSTITHPSEFDFYLCSHAGIQGTSRPSHYQVLWDDNCFTADELQLLTYQLCHTYVRCTRSVSIPAPAYYARLVAFRARYHLVDKDHDSAEGSHVSGQSNGRDPQALAKAVQIHHDTQHTMYFA 861

[Close]

BLAST of AGO-2 vs. Ensembl Celegans
Match: alg-1 (pep chromosome:WBcel235:X:13949114:13956261:1 gene:WBGene00000105.1 transcript:F48F7.1b.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:alg-1)

HSP 1 Score: 1261.51 bits (3263), Expect = 0.000e+0
Identity = 591/871 (67.85%), Postives = 705/871 (80.94%), Query Frame = 1

Query:  271 VYFQPPSRPDQGTDGRTIQLKANHFEIVMPKGFLHHYDITITPEKCPRRVNRDIIQAMVNNMHYQKYFYNQKPVFDGRRNMYTREPLSIGKEKLELEVILPGEGK-DRVFKVCLKHVSEVSLFALEEALQGRRQTIPAETVTALDVIMRHLPSMTYTPVGRSFF---------------------------HNTGDY--DNPLGGGREVWFGFHQSVRPSQWKMMLNIDVSATAFYKEQSVINFMFEVLEIDKDL---KRPLTDSQRVKFTKEIKGLKVEINHCGPIKRKYRVCNVTRRSAQSQTFPLQSEQGQTIECTVTKYFQDRYGMKLQHPHLPCLQVGQEQKHTYLPLEVCNIVSGQRCIKKLTDMQTSTMIKATARSAPDREKEINNLVRRSNFNADPHLQIFGVSVNTRMADIQGRVIPAPKIQYGGRTKAQATPQQGVWDMRGKQFFSGIEIKVWAIACFAPQRTVREDSLRTFTQQLQKISNDAGMPIVGQPCFCKYATGQDQVEPMFRYLKNSFSGLQLIVVVLPGKTPVYAEVKRVGDIIFGLATQCVQAKNVNKPSPQTLSNLCLKINVKLGGINSILVPSVRPAVFKEPVIFLGADFTHPPAGDKTKPSIAAVVGSMDAHPSRYAATVSVQPHRQETIQDLAAMVKELLIQFYKSTRFKPTRIIYYRDGVSEGQFLNVLNHELKAIREACIKLEMSYQPGITFVVVQKRHHTRLFCSDKKDQMGRSGNIPAGTTVDQIITHPTEFDFYLCSHAGIQGTSRPSHYHVLWDDNRFSADEIQTLTYQLCHTYVRCTRSVSIPAPAYYAHLVAFRARYHLVEKELDSGEGSQKSGNSDERNPTAMMRAVTVHSETLKVMYFA 2784
            + FQ P RP+ G +GR+I L+ANHF + +P G + HY + +TP+KCPRRVNR+II  +++   + KYF N +PV+DG+RNMYTREPL IG+E+++ +V LPG+   +R F V LK V +VSL  LE+A++GR + +P E V A+DVI+RHLPS+ YTPVGRSFF                           H+ G Y  ++ LGGGREVWFGFHQSVRPSQWKMMLNIDVSATAFY+   VI F+ EVLE+       +R L+D+QRVKFTKEI+GLK+EI HCG ++RKYRVCNVTRR AQ+QTFPLQ E GQTIECTV KYF D+Y ++L++PHLPCLQVGQEQKHTYLP EVCNIV GQRCIKKLTD+QTSTMIKATARSAP+RE+EI+NLVR++ F+ADP    FG+++N  M +++GRV+ APK+ YGGRT+A A P QGVWDMRGKQF +GI+++VWAIACFA Q+ V+E+ LR FT QLQ+ISNDAGMPIVG PCFCKYA G +QVEPMF+YLK ++SG+QL+VVVLPGKTPVYAEVKRVGD + G+ATQCVQAKN  + +PQTLSNLCLK+NVKLGG+NSIL+P+VRP +F EPVIF G D THPPAGD  KPSIAAVVGSMDAHPSRYAATV VQ HRQE I DL  MV+ELL+QFY++TRFKP RI+ YRDGVSEGQF NVL +EL+AIREAC+ LE  YQPGITF+ VQKRHHTRLF  DKKDQ+G++ NIP GTTVD  ITHPTEFDFYLCSHAGIQGTSRPSHYHVLWDDN  +ADE+Q LTYQ+CHTYVRCTRSVSIPAPAYYAHLVAFRARYHLV++E DSGEGSQ SG S++   + M RAV VH +   VMYFA
Sbjct:  155 IQFQCPRRPNHGVEGRSILLRANHFAVRIPGGTIQHYQVDVTPDKCPRRVNREIISCLISA--FSKYFTNIRPVYDGKRNMYTREPLPIGRERMDFDVTLPGDSAVERQFSVSLKWVGQVSLSTLEDAMEGRVRQVPFEAVQAMDVILRHLPSLKYTPVGRSFFSPPVPNASGVMAGSCPPQASGAVAGGAHSAGQYHAESKLGGGREVWFGFHQSVRPSQWKMMLNIDVSATAFYRSMPVIEFIAEVLELPVQALAERRALSDAQRVKFTKEIRGLKIEITHCGQMRRKYRVCNVTRRPAQTQTFPLQLETGQTIECTVAKYFYDKYRIQLKYPHLPCLQVGQEQKHTYLPPEVCNIVPGQRCIKKLTDVQTSTMIKATARSAPEREREISNLVRKAEFSADPFAHEFGITINPAMTEVKGRVLSAPKLLYGGRTRATALPNQGVWDMRGKQFHTGIDVRVWAIACFAQQQHVKENDLRMFTNQLQRISNDAGMPIVGNPCFCKYAVGVEQVEPMFKYLKQNYSGIQLVVVVLPGKTPVYAEVKRVGDTVLGIATQCVQAKNAIRTTPQTLSNLCLKMNVKLGGVNSILLPNVRPRIFNEPVIFFGCDITHPPAGDSRKPSIAAVVGSMDAHPSRYAATVRVQQHRQEIISDLTYMVRELLVQFYRNTRFKPARIVVYRDGVSEGQFFNVLQYELRAIREACMMLERGYQPGITFIAVQKRHHTRLFAVDKKDQVGKAYNIPPGTTVDVGITHPTEFDFYLCSHAGIQGTSRPSHYHVLWDDNNLTADELQQLTYQMCHTYVRCTRSVSIPAPAYYAHLVAFRARYHLVDREHDSGEGSQPSGTSEDTTLSNMARAVQVHPDANNVMYFA 1023

[Close]

BLAST of AGO-2 vs. Ensembl Celegans
Match: alg-1 (pep chromosome:WBcel235:X:13951262:13956261:1 gene:WBGene00000105.1 transcript:F48F7.1a.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:alg-1)

HSP 1 Score: 1260.36 bits (3260), Expect = 0.000e+0
Identity = 591/871 (67.85%), Postives = 705/871 (80.94%), Query Frame = 1

Query:  271 VYFQPPSRPDQGTDGRTIQLKANHFEIVMPKGFLHHYDITITPEKCPRRVNRDIIQAMVNNMHYQKYFYNQKPVFDGRRNMYTREPLSIGKEKLELEVILPGEGK-DRVFKVCLKHVSEVSLFALEEALQGRRQTIPAETVTALDVIMRHLPSMTYTPVGRSFF---------------------------HNTGDY--DNPLGGGREVWFGFHQSVRPSQWKMMLNIDVSATAFYKEQSVINFMFEVLEIDKDL---KRPLTDSQRVKFTKEIKGLKVEINHCGPIKRKYRVCNVTRRSAQSQTFPLQSEQGQTIECTVTKYFQDRYGMKLQHPHLPCLQVGQEQKHTYLPLEVCNIVSGQRCIKKLTDMQTSTMIKATARSAPDREKEINNLVRRSNFNADPHLQIFGVSVNTRMADIQGRVIPAPKIQYGGRTKAQATPQQGVWDMRGKQFFSGIEIKVWAIACFAPQRTVREDSLRTFTQQLQKISNDAGMPIVGQPCFCKYATGQDQVEPMFRYLKNSFSGLQLIVVVLPGKTPVYAEVKRVGDIIFGLATQCVQAKNVNKPSPQTLSNLCLKINVKLGGINSILVPSVRPAVFKEPVIFLGADFTHPPAGDKTKPSIAAVVGSMDAHPSRYAATVSVQPHRQETIQDLAAMVKELLIQFYKSTRFKPTRIIYYRDGVSEGQFLNVLNHELKAIREACIKLEMSYQPGITFVVVQKRHHTRLFCSDKKDQMGRSGNIPAGTTVDQIITHPTEFDFYLCSHAGIQGTSRPSHYHVLWDDNRFSADEIQTLTYQLCHTYVRCTRSVSIPAPAYYAHLVAFRARYHLVEKELDSGEGSQKSGNSDERNPTAMMRAVTVHSETLKVMYFA 2784
            + FQ P RP+ G +GR+I L+ANHF + +P G + HY + +TP+KCPRRVNR+II  +++   + KYF N +PV+DG+RNMYTREPL IG+E+++ +V LPG+   +R F V LK V +VSL  LE+A++GR + +P E V A+DVI+RHLPS+ YTPVGRSFF                           H+ G Y  ++ LGGGREVWFGFHQSVRPSQWKMMLNIDVSATAFY+   VI F+ EVLE+       +R L+D+QRVKFTKEI+GLK+EI HCG ++RKYRVCNVTRR AQ+QTFPLQ E GQTIECTV KYF D+Y ++L++PHLPCLQVGQEQKHTYLP EVCNIV GQRCIKKLTD+QTSTMIKATARSAP+RE+EI+NLVR++ F+ADP    FG+++N  M +++GRV+ APK+ YGGRT+A A P QGVWDMRGKQF +GI+++VWAIACFA Q+ V+E+ LR FT QLQ+ISNDAGMPIVG PCFCKYA G +QVEPMF+YLK ++SG+QL+VVVLPGKTPVYAEVKRVGD + G+ATQCVQAKN  + +PQTLSNLCLK+NVKLGG+NSIL+P+VRP +F EPVIF G D THPPAGD  KPSIAAVVGSMDAHPSRYAATV VQ HRQE I DL  MV+ELL+QFY++TRFKP RI+ YRDGVSEGQF NVL +EL+AIREAC+ LE  YQPGITF+ VQKRHHTRLF  DKKDQ+G++ NIP GTTVD  ITHPTEFDFYLCSHAGIQGTSRPSHYHVLWDDN  +ADE+Q LTYQ+CHTYVRCTRSVSIPAPAYYAHLVAFRARYHLV++E DSGEGSQ SG S++   + M RAV VH +   VMYFA
Sbjct:  134 IQFQCPRRPNHGVEGRSILLRANHFAVRIPGGTIQHYQVDVTPDKCPRRVNREIISCLISA--FSKYFTNIRPVYDGKRNMYTREPLPIGRERMDFDVTLPGDSAVERQFSVSLKWVGQVSLSTLEDAMEGRVRQVPFEAVQAMDVILRHLPSLKYTPVGRSFFSPPVPNASGVMAGSCPPQASGAVAGGAHSAGQYHAESKLGGGREVWFGFHQSVRPSQWKMMLNIDVSATAFYRSMPVIEFIAEVLELPVQALAERRALSDAQRVKFTKEIRGLKIEITHCGQMRRKYRVCNVTRRPAQTQTFPLQLETGQTIECTVAKYFYDKYRIQLKYPHLPCLQVGQEQKHTYLPPEVCNIVPGQRCIKKLTDVQTSTMIKATARSAPEREREISNLVRKAEFSADPFAHEFGITINPAMTEVKGRVLSAPKLLYGGRTRATALPNQGVWDMRGKQFHTGIDVRVWAIACFAQQQHVKENDLRMFTNQLQRISNDAGMPIVGNPCFCKYAVGVEQVEPMFKYLKQNYSGIQLVVVVLPGKTPVYAEVKRVGDTVLGIATQCVQAKNAIRTTPQTLSNLCLKMNVKLGGVNSILLPNVRPRIFNEPVIFFGCDITHPPAGDSRKPSIAAVVGSMDAHPSRYAATVRVQQHRQEIISDLTYMVRELLVQFYRNTRFKPARIVVYRDGVSEGQFFNVLQYELRAIREACMMLERGYQPGITFIAVQKRHHTRLFAVDKKDQVGKAYNIPPGTTVDVGITHPTEFDFYLCSHAGIQGTSRPSHYHVLWDDNNLTADELQQLTYQMCHTYVRCTRSVSIPAPAYYAHLVAFRARYHLVDREHDSGEGSQPSGTSEDTTLSNMARAVQVHPDANNVMYFA 1002

[Close]

BLAST of AGO-2 vs. Ensembl Celegans
Match: alg-2 (pep chromosome:WBcel235:II:874160:879001:1 gene:WBGene00000106.1 transcript:T07D3.7b.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:alg-2)

HSP 1 Score: 1207.59 bits (3123), Expect = 0.000e+0
Identity = 570/853 (66.82%), Postives = 689/853 (80.77%), Query Frame = 1

Query:  271 VYFQPPSRPDQGTDGRTIQLKANHFEIVMPKGFLHHYDITITPEKCPRRVNRDIIQAMVNNMHYQKYFYNQKPVFDGRRNMYTREPLSIGKEKLELEVILPGEGK-DRVFKVCLKHVSEVSLFALEEALQGRRQTIPAETVTALDVIMRHLPSMTYTPVGRSFFHNTG--------DYDNPLGGGREVWFGFHQSVRPSQWKMMLNIDVSATAFYKEQSVINFMFEVLEIDKDL---KRPLTDSQRVKFTKEIKGLKVEINHCGPIKRKYRVCNVTRRSAQSQTFPLQSEQGQTIECTVTKYFQDRYGMKLQHPHLPCLQVGQEQKHTYLPLEVCNIVSGQRCIKKLTDMQTSTMIKATARSAPDREKEINNLVRRSNFNADPHLQIFGVSVNTRMADIQGRVIPAPKIQYGGRTKAQ-ATPQQGVWDMRGKQFFSGIEIKVWAIACFAPQRTVREDSLRTFTQQLQKISNDAGMPIVGQPCFCKYATGQDQVEPMFRYLKNSFSGLQLIVVVLPGKTPVYAEVKRVGDIIFGLATQCVQAKNVNKPSPQTLSNLCLKINVKLGGINSILVPSVRPAVFKEPVIFLGADFTHPPAGDKTKPSIAAVVGSMDAHPSRYAATVSVQPHRQETIQDLAAMVKELLIQFYKSTRFKPTRIIYYRDGVSEGQFLNVLNHELKAIREACIKLEMSYQPGITFVVVQKRHHTRLFCSDKKDQMGRSGNIPAGTTVDQIITHPTEFDFYLCSHAGIQGTSRPSHYHVLWDDNRFSADEIQTLTYQLCHTYVRCTRSVSIPAPAYYAHLVAFRARYHLVEKELDSG-EGSQKSGNSDERNP-TAMMRAVTVHSETLKVMYFA 2784
            V FQ P RP+ G +GR+I L+ANHF + +P G + HY I + P+KCPRRVNR++I  ++++  + KYF N +PV+DG+RNMYTREPL IG E +  EV LPG+   +R F V +K + +V L AL++A++GR + +P E V ++DVI+RHLPS+ YTPVGRSFF   G          ++ LGGGREVWFGFHQSVRPSQWKMMLNIDVSATAFY+   VI F+ EVLE+       +R L+D+QRVKFTKEI+GLK+EI HCG ++RKYRVCNVTRR AQ+QTFPLQ E GQTIECTV KYF D+Y ++L++PHLPCLQVGQEQKHTYLP EVC+IV GQRC+KKLTD+QTSTMIKATARSAP+RE+EI  LV ++  +ADP    FG+++N  M +++GRV+ APK+ YGGR +A  A P QGVWDMRGKQF +G+E++ WAIACFA Q  V+E+ LR FT QLQ+IS DAGMPI+G P FCKYA+G +QVEPMF+YLK ++S +QLIVVVLPGKTP+YAEVKRVGD + G+ATQCVQAKN  + +PQTLSNLCLK+NVKLGG+NSIL+P+VRP +F EPVIFLG D THP AGD  KPSIAAVVGSMDAHPSRYAATV VQ HRQE I DL  MV+ELL+QFY++TRFKP RI+ YRDGVSEGQ  NVL +EL+AIREAC+ LE  YQPGITF+ VQKRHHTRLF +DK DQ+G++ NIP GTTVD  ITHPTEFDF+LCSHAGIQGTSRPSHYHVLWDDN  +ADE+Q LTYQ+CHTYVRCTRSVSIPAPAYYAHLVAFRARYHLV+++  SG EGSQ SG S E    ++M +AV VH ++  VMYFA
Sbjct:   41 VQFQCPVRPNHGVEGRSILLRANHFAVRIPGGSVQHYQIDVFPDKCPRRVNREVIGCLISS--FSKYFTNIRPVYDGKRNMYTREPLPIGTEPMNFEVTLPGDSAVERKFSVTMKWIGQVCLSALDDAMEGRVRQVPHEAVQSIDVILRHLPSLKYTPVGRSFFTPPGVMKPGMQMHQESKLGGGREVWFGFHQSVRPSQWKMMLNIDVSATAFYRAMPVIEFVAEVLELPVQALAERRALSDAQRVKFTKEIRGLKIEITHCGAVRRKYRVCNVTRRPAQTQTFPLQLETGQTIECTVAKYFFDKYRIQLKYPHLPCLQVGQEQKHTYLPPEVCDIVPGQRCLKKLTDVQTSTMIKATARSAPEREREICKLVSKAELSADPFAHEFGITINPAMTEVKGRVLSAPKLLYGGRHRATTALPNQGVWDMRGKQFHTGMEVRTWAIACFAQQSHVKENDLRMFTTQLQRISTDAGMPIIGTPMFCKYASGVEQVEPMFKYLKQTYSAIQLIVVVLPGKTPIYAEVKRVGDTVLGIATQCVQAKNAIRTTPQTLSNLCLKMNVKLGGVNSILLPNVRPRIFNEPVIFLGCDITHPAAGDTRKPSIAAVVGSMDAHPSRYAATVRVQQHRQEIITDLTYMVRELLVQFYRNTRFKPARIVVYRDGVSEGQLFNVLQYELRAIREACVMLESGYQPGITFIAVQKRHHTRLFAADKADQVGKAFNIPPGTTVDVGITHPTEFDFFLCSHAGIQGTSRPSHYHVLWDDNDLTADELQQLTYQMCHTYVRCTRSVSIPAPAYYAHLVAFRARYHLVDRDHGSGEEGSQPSGTSSEDTTLSSMAKAVQVHPDSNNVMYFA 891

[Close]

BLAST of AGO-2 vs. Ensembl Celegans
Match: alg-2 (pep chromosome:WBcel235:II:873176:878945:1 gene:WBGene00000106.1 transcript:T07D3.7a.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:alg-2)

HSP 1 Score: 1207.59 bits (3123), Expect = 0.000e+0
Identity = 570/853 (66.82%), Postives = 689/853 (80.77%), Query Frame = 1

Query:  271 VYFQPPSRPDQGTDGRTIQLKANHFEIVMPKGFLHHYDITITPEKCPRRVNRDIIQAMVNNMHYQKYFYNQKPVFDGRRNMYTREPLSIGKEKLELEVILPGEGK-DRVFKVCLKHVSEVSLFALEEALQGRRQTIPAETVTALDVIMRHLPSMTYTPVGRSFFHNTG--------DYDNPLGGGREVWFGFHQSVRPSQWKMMLNIDVSATAFYKEQSVINFMFEVLEIDKDL---KRPLTDSQRVKFTKEIKGLKVEINHCGPIKRKYRVCNVTRRSAQSQTFPLQSEQGQTIECTVTKYFQDRYGMKLQHPHLPCLQVGQEQKHTYLPLEVCNIVSGQRCIKKLTDMQTSTMIKATARSAPDREKEINNLVRRSNFNADPHLQIFGVSVNTRMADIQGRVIPAPKIQYGGRTKAQ-ATPQQGVWDMRGKQFFSGIEIKVWAIACFAPQRTVREDSLRTFTQQLQKISNDAGMPIVGQPCFCKYATGQDQVEPMFRYLKNSFSGLQLIVVVLPGKTPVYAEVKRVGDIIFGLATQCVQAKNVNKPSPQTLSNLCLKINVKLGGINSILVPSVRPAVFKEPVIFLGADFTHPPAGDKTKPSIAAVVGSMDAHPSRYAATVSVQPHRQETIQDLAAMVKELLIQFYKSTRFKPTRIIYYRDGVSEGQFLNVLNHELKAIREACIKLEMSYQPGITFVVVQKRHHTRLFCSDKKDQMGRSGNIPAGTTVDQIITHPTEFDFYLCSHAGIQGTSRPSHYHVLWDDNRFSADEIQTLTYQLCHTYVRCTRSVSIPAPAYYAHLVAFRARYHLVEKELDSG-EGSQKSGNSDERNP-TAMMRAVTVHSETLKVMYFA 2784
            V FQ P RP+ G +GR+I L+ANHF + +P G + HY I + P+KCPRRVNR++I  ++++  + KYF N +PV+DG+RNMYTREPL IG E +  EV LPG+   +R F V +K + +V L AL++A++GR + +P E V ++DVI+RHLPS+ YTPVGRSFF   G          ++ LGGGREVWFGFHQSVRPSQWKMMLNIDVSATAFY+   VI F+ EVLE+       +R L+D+QRVKFTKEI+GLK+EI HCG ++RKYRVCNVTRR AQ+QTFPLQ E GQTIECTV KYF D+Y ++L++PHLPCLQVGQEQKHTYLP EVC+IV GQRC+KKLTD+QTSTMIKATARSAP+RE+EI  LV ++  +ADP    FG+++N  M +++GRV+ APK+ YGGR +A  A P QGVWDMRGKQF +G+E++ WAIACFA Q  V+E+ LR FT QLQ+IS DAGMPI+G P FCKYA+G +QVEPMF+YLK ++S +QLIVVVLPGKTP+YAEVKRVGD + G+ATQCVQAKN  + +PQTLSNLCLK+NVKLGG+NSIL+P+VRP +F EPVIFLG D THP AGD  KPSIAAVVGSMDAHPSRYAATV VQ HRQE I DL  MV+ELL+QFY++TRFKP RI+ YRDGVSEGQ  NVL +EL+AIREAC+ LE  YQPGITF+ VQKRHHTRLF +DK DQ+G++ NIP GTTVD  ITHPTEFDF+LCSHAGIQGTSRPSHYHVLWDDN  +ADE+Q LTYQ+CHTYVRCTRSVSIPAPAYYAHLVAFRARYHLV+++  SG EGSQ SG S E    ++M +AV VH ++  VMYFA
Sbjct:   60 VQFQCPVRPNHGVEGRSILLRANHFAVRIPGGSVQHYQIDVFPDKCPRRVNREVIGCLISS--FSKYFTNIRPVYDGKRNMYTREPLPIGTEPMNFEVTLPGDSAVERKFSVTMKWIGQVCLSALDDAMEGRVRQVPHEAVQSIDVILRHLPSLKYTPVGRSFFTPPGVMKPGMQMHQESKLGGGREVWFGFHQSVRPSQWKMMLNIDVSATAFYRAMPVIEFVAEVLELPVQALAERRALSDAQRVKFTKEIRGLKIEITHCGAVRRKYRVCNVTRRPAQTQTFPLQLETGQTIECTVAKYFFDKYRIQLKYPHLPCLQVGQEQKHTYLPPEVCDIVPGQRCLKKLTDVQTSTMIKATARSAPEREREICKLVSKAELSADPFAHEFGITINPAMTEVKGRVLSAPKLLYGGRHRATTALPNQGVWDMRGKQFHTGMEVRTWAIACFAQQSHVKENDLRMFTTQLQRISTDAGMPIIGTPMFCKYASGVEQVEPMFKYLKQTYSAIQLIVVVLPGKTPIYAEVKRVGDTVLGIATQCVQAKNAIRTTPQTLSNLCLKMNVKLGGVNSILLPNVRPRIFNEPVIFLGCDITHPAAGDTRKPSIAAVVGSMDAHPSRYAATVRVQQHRQEIITDLTYMVRELLVQFYRNTRFKPARIVVYRDGVSEGQLFNVLQYELRAIREACVMLESGYQPGITFIAVQKRHHTRLFAADKADQVGKAFNIPPGTTVDVGITHPTEFDFFLCSHAGIQGTSRPSHYHVLWDDNDLTADELQQLTYQMCHTYVRCTRSVSIPAPAYYAHLVAFRARYHLVDRDHGSGEEGSQPSGTSSEDTTLSSMAKAVQVHPDSNNVMYFA 910

[Close]

BLAST of AGO-2 vs. Ensembl Celegans
Match: alg-5 (pep chromosome:WBcel235:I:9989802:9993975:1 gene:WBGene00011945.1 transcript:T23D8.7.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:alg-5)

HSP 1 Score: 588.186 bits (1515), Expect = 0.000e+0
Identity = 321/834 (38.49%), Postives = 490/834 (58.75%), Query Frame = 1

Query:  277 FQPPSRPDQGTDGRTIQLKANHFEIVMPKGFLHHYDITITPEKCPRRVNRDIIQAMVNNMHYQKYFYNQKP-VFDGRRNMYTREPLSI---GKEKLELEVILPGEGKDRVFKVCLKHVSEVSLFALEEALQGRR-QTIPAETVTALDVIMRHLPSMTYTPVGRSFF-----------HNTGDYDNPLGGGREVWFGFHQSVRPSQWKMMLNIDVSATAFYKEQSVINFMFEVLEIDKDL---KRPLTDSQRVKFTKEIKGLKVEINHCGPIKRKYRVCNVTRRSAQSQTFPLQSEQGQ--TIECTVTKYFQDRYGMKLQHPHLPCLQVGQEQKHTYLPLEVCNIVSGQRCIKKLTDMQTSTMIKATARSAPDREKEINNLVRRSNFNADPHLQIFGVSVNTRMADIQGRVIPAPKIQYGG----RTKAQATPQQGVWDMRGKQFFSGIEIKVWAIACFAPQRTVREDSLRTFTQQLQKISNDAGMPIVGQPCFCKYATGQDQVEPMFRYLKNSFSGLQLIVVVLPGKTPVYAEVKRVGDIIFGLATQCVQAKNVNKPSPQTLSNLCLKINVKLGGINSILVPSVRPAVFKEPVIFLGADFTHPPAGDKT---------KPSIAAVVGSMDAHPSRYAATVSVQPHRQETIQDLAAMVKELLIQFYKSTRFKPTRIIYYRDGVSEGQFLNVLNHELKAIREACIKLEMSYQPGITFVVVQKRHHTRLFCSDKKDQMGRSGNIPAGTTVDQIITHPTEFDFYLCSHAGIQGTSRPSHYHVLWDDNRFSADEIQTLTYQLCHTYVRCTRSVSIPAPAYYAHLVAFRARYHLVEKELD 2676
            F+   +P   T GR + L ANHF+I      +H Y I   P+   +++NR I++ +      Q     + P VFDG   +Y+ E +++       + +  ++  +    +FK+ L HV   S     + + G + Q      + A+D + R   +  +  V +SFF           H  G     LG GREV +GF+Q+V  +   + +N+DV+ T FY+  +++ F+ E+LE+        R L+D Q+ KF +E+ GLKVE  HC    R++RV   T +  ++ +F L    G   +   ++ +Y++ RY + L + HLPC++VG+  +   LPLE+C +VSGQRCIKKL + Q + +I+AT+R+A +R+  + +L  R   + D +   FG+ V  ++  I+GRV+P P++ Y      R +    P  G WDMRGK F+SGI+I+ WAI CFA    + E S+R+F + L  ++++ GMP + +  FC+YA   DQ   +  +L   ++ LQL++ ++PGK+ VY E+KR G+++ GL TQCV+++NV+K SP TLSNLC+KIN KLGGIN IL  S   ++  EPV+F+G   T       +           SIA +VGSMD HP++++     QP  Q TI D+  M +E +I F KST FKP +II YR G+++     ++  EL+A+R+AC  +E  +QPGITF+ +   HHTRLF +++KD++G S N+PAGT V+  IT    F+FYL SHAGIQGTSRP+ Y V+WDDN   + +I  +TYQLCHT  RCTRSVSIP+P YYA LVA RA+  + ++  D
Sbjct:   66 FKLIGKPLPSTTGRFLSLLANHFQITCNGSIIHQYYIRFDPDIPSKKLNRTILRTL----QEQNPGLIECPLVFDGIHTVYSTELINVKEVNNSVINVAGVVNTKESPNLFKLYLTHVD--SFLLDTKIITGNQDQNQKLRMMHAIDTVFRQTSTGNFHAVLQSFFSIAQNSAIEPSHGLGWGTVNLGVGREVCYGFYQNVVETFDTLTMNLDVATTTFYRPVALVEFLAEILEVPLATVTDGRSLSDVQKKKFNREVAGLKVETRHCS-CPRRFRVARCTWKPTENISFHLSETAGNQDSKPLSLVEYYKRRYNIDLTYKHLPCIEVGR-TRECILPLELCYVVSGQRCIKKLNEQQIANLIRATSRNATERQNAVMSLQNRLKMDNDVNAVKFGLKVEAQLLKIEGRVLPVPRLLYRSPNLKRQECVTVPNNGTWDMRGKNFYSGIQIREWAIVCFASPEIIGEASMRSFVRNLVNVASEIGMPFLEEHRFCRYAE-PDQTVKLLEHLNEQYN-LQLVLCIVPGKSVVYGELKRKGELL-GLTTQCVRSQNVSKASPHTLSNLCMKINSKLGGINVIL-SSPPQSLNSEPVLFIGCHLTRSSLASSSDSTSSIAHCDSSIACLVGSMDGHPTQFSPIFRTQPRHQRTIVDMCEMTREAIINFRKSTGFKPHKIIIYRAGIADVTVDEIMQTELRAVRDACAMIEYGFQPGITFIGLDVTHHTRLFAANEKDRVGNSQNVPAGTLVETGITVNNLFEFYLVSHAGIQGTSRPTKYVVMWDDNSIPSADIHEMTYQLCHTQSRCTRSVSIPSPVYYAKLVAQRAKILMADENFD 887

[Close]

BLAST of AGO-2 vs. Ensembl Fly
Match: AGO1 (gene:FBgn0262739 transcript:FBtr0305592)

HSP 1 Score: 1360.51 bits (3520), Expect = 0.000e+0
Identity = 644/854 (75.41%), Postives = 734/854 (85.95%), Query Frame = 1

Query:  277 FQPPSRPDQGTDGRTIQLKANHFEIVMPKGFLHHYDITITPEKCPRRVNRDIIQAMVNNMHYQKYFYNQKPVFDGRRNMYTREPLSIGKEKLELEVILPGEGKDRVFKVCLKHVSEVSLFALEEALQGRRQTIPAETVTALDVIMRHLPSMTYTPVGRSFFHNTGDYDNPLGGGREVWFGFHQSVRPSQWKMMLNIDVSATAFYKEQSVINFMFEVLEID--KDLKRPLTDSQRVKFTKEIKGLKVEINHCGPIKRKYRVCNVTRRSAQSQTFPLQSEQGQTIECTVTKYFQDRYGMKLQHPHLPCLQVGQEQKHTYLPLEVCNIVSGQRCIKKLTDMQTSTMIKATARSAPDREKEINNLVRRSNFNADPHLQIFGVSVNTRMADIQGRVIPAPKIQYGGRTK---------------AQATPQQGVWDMRGKQFFSGIEIKVWAIACFAPQRTVREDSLRTFTQQLQKISNDAGMPIVGQPCFCKYATGQDQVEPMFRYLKNSFSGLQLIVVVLPGKTPVYAEVKRVGDIIFGLATQCVQAKNVNKPSPQTLSNLCLKINVKLGGINSILVPSVRPAVFKEPVIFLGADFTHPPAGDKTKPSIAAVVGSMDAHPSRYAATVSVQPHRQETIQDLAAMVKELLIQFYKST-RFKPTRIIYYRDGVSEGQFLNVLNHELKAIREACIKLEMSYQPGITFVVVQKRHHTRLFCSDKKDQMGRSGNIPAGTTVDQIITHPTEFDFYLCSHAGIQGTSRPSHYHVLWDDNRFSADEIQTLTYQLCHTYVRCTRSVSIPAPAYYAHLVAFRARYHLVEKELDSGEGSQKSGNSDERNPTAMMRAVTVHSETLKVMYFA 2784
            F  P RP+ G +GR I L+ANHF++ MP+G++HHYDI I P+KCPR+VNR+II+ MV+   Y K F   KPVFDGR N+YTR+PL IG E+LELEV LPGEGKDR+F+V +K  ++VSLF LEEAL+GR + IP + + ALDV+MRHLPSMTYTPVGRSFF +   Y +PLGGGREVWFGFHQSVRPSQWKMMLNIDVSATAFYK Q VI+FM EVL+I    + ++PLTDSQRVKFTKEIKGLK+EI HCG ++RKYRVCNVTRR AQ Q+FPLQ E GQT+ECTV KYF D+Y MKL++PHLPCLQVGQE KHTYLPLEVCNIV+GQRCIKKLTDMQTSTMIKATARSAPDRE+EINNLV+R++FN D ++Q FG++++  M +++GRV+P PK+QYGGR                 + A+P QGVWDMRGKQFF+G+EI++WAIACFAPQRTVRED+LR FTQQLQKISNDAGMPI+GQPCFCKYATG DQVEPMFRYLK +F GLQL+VVVLPGKTPVYAEVKRVGD + G+ATQCVQAKNVNK SPQTLSNLCLKINVKLGGINSILVPS+RP VF EPVIFLGAD THPPAGD  KPSIAAVVGSMDAHPSRYAATV VQ HRQE IQ+L++MV+ELLI FYKST  +KP RII YRDGVSEGQF +VL HEL AIREACIKLE  Y+PGITF+VVQKRHHTRLFC++KK+Q G+SGNIPAGTTVD  ITHPTEFDFYLCSH GIQGTSRPSHYHVLWDDN F +DE+Q LTYQLCHTYVRCTRSVSIPAPAYYAHLVAFRARYHLVEKE DSGEGS +SG S++R P AM RA+TVH++T KVMYFA
Sbjct:  133 FTCPRRPNLGREGRPIVLRANHFQVTMPRGYVHHYDINIQPDKCPRKVNREIIETMVHA--YSKIFGVLKPVFDGRNNLYTRDPLPIGNERLELEVTLPGEGKDRIFRVTIKWQAQVSLFNLEEALEGRTRQIPYDAILALDVVMRHLPSMTYTPVGRSFFSSPEGYYHPLGGGREVWFGFHQSVRPSQWKMMLNIDVSATAFYKAQPVIDFMCEVLDIRDINEQRKPLTDSQRVKFTKEIKGLKIEITHCGQMRRKYRVCNVTRRPAQMQSFPLQLENGQTVECTVAKYFLDKYRMKLRYPHLPCLQVGQEHKHTYLPLEVCNIVAGQRCIKKLTDMQTSTMIKATARSAPDREREINNLVKRADFNNDSYVQEFGLTISNSMMEVRGRVLPPPKLQYGGRVSTGLTGQQLFPPQNKVSLASPNQGVWDMRGKQFFTGVEIRIWAIACFAPQRTVREDALRNFTQQLQKISNDAGMPIIGQPCFCKYATGPDQVEPMFRYLKITFPGLQLVVVVLPGKTPVYAEVKRVGDTVLGMATQCVQAKNVNKTSPQTLSNLCLKINVKLGGINSILVPSIRPKVFNEPVIFLGADVTHPPAGDNKKPSIAAVVGSMDAHPSRYAATVRVQQHRQEIIQELSSMVRELLIMFYKSTGGYKPHRIILYRDGVSEGQFPHVLQHELTAIREACIKLEPEYRPGITFIVVQKRHHTRLFCAEKKEQSGKSGNIPAGTTVDVGITHPTEFDFYLCSHQGIQGTSRPSHYHVLWDDNHFDSDELQCLTYQLCHTYVRCTRSVSIPAPAYYAHLVAFRARYHLVEKEHDSGEGSHQSGCSEDRTPGAMARAITVHADTKKVMYFA 984

[Close]

BLAST of AGO-2 vs. Ensembl Fly
Match: AGO1 (gene:FBgn0262739 transcript:FBtr0087612)

HSP 1 Score: 1360.51 bits (3520), Expect = 0.000e+0
Identity = 644/854 (75.41%), Postives = 734/854 (85.95%), Query Frame = 1

Query:  277 FQPPSRPDQGTDGRTIQLKANHFEIVMPKGFLHHYDITITPEKCPRRVNRDIIQAMVNNMHYQKYFYNQKPVFDGRRNMYTREPLSIGKEKLELEVILPGEGKDRVFKVCLKHVSEVSLFALEEALQGRRQTIPAETVTALDVIMRHLPSMTYTPVGRSFFHNTGDYDNPLGGGREVWFGFHQSVRPSQWKMMLNIDVSATAFYKEQSVINFMFEVLEID--KDLKRPLTDSQRVKFTKEIKGLKVEINHCGPIKRKYRVCNVTRRSAQSQTFPLQSEQGQTIECTVTKYFQDRYGMKLQHPHLPCLQVGQEQKHTYLPLEVCNIVSGQRCIKKLTDMQTSTMIKATARSAPDREKEINNLVRRSNFNADPHLQIFGVSVNTRMADIQGRVIPAPKIQYGGRTK---------------AQATPQQGVWDMRGKQFFSGIEIKVWAIACFAPQRTVREDSLRTFTQQLQKISNDAGMPIVGQPCFCKYATGQDQVEPMFRYLKNSFSGLQLIVVVLPGKTPVYAEVKRVGDIIFGLATQCVQAKNVNKPSPQTLSNLCLKINVKLGGINSILVPSVRPAVFKEPVIFLGADFTHPPAGDKTKPSIAAVVGSMDAHPSRYAATVSVQPHRQETIQDLAAMVKELLIQFYKST-RFKPTRIIYYRDGVSEGQFLNVLNHELKAIREACIKLEMSYQPGITFVVVQKRHHTRLFCSDKKDQMGRSGNIPAGTTVDQIITHPTEFDFYLCSHAGIQGTSRPSHYHVLWDDNRFSADEIQTLTYQLCHTYVRCTRSVSIPAPAYYAHLVAFRARYHLVEKELDSGEGSQKSGNSDERNPTAMMRAVTVHSETLKVMYFA 2784
            F  P RP+ G +GR I L+ANHF++ MP+G++HHYDI I P+KCPR+VNR+II+ MV+   Y K F   KPVFDGR N+YTR+PL IG E+LELEV LPGEGKDR+F+V +K  ++VSLF LEEAL+GR + IP + + ALDV+MRHLPSMTYTPVGRSFF +   Y +PLGGGREVWFGFHQSVRPSQWKMMLNIDVSATAFYK Q VI+FM EVL+I    + ++PLTDSQRVKFTKEIKGLK+EI HCG ++RKYRVCNVTRR AQ Q+FPLQ E GQT+ECTV KYF D+Y MKL++PHLPCLQVGQE KHTYLPLEVCNIV+GQRCIKKLTDMQTSTMIKATARSAPDRE+EINNLV+R++FN D ++Q FG++++  M +++GRV+P PK+QYGGR                 + A+P QGVWDMRGKQFF+G+EI++WAIACFAPQRTVRED+LR FTQQLQKISNDAGMPI+GQPCFCKYATG DQVEPMFRYLK +F GLQL+VVVLPGKTPVYAEVKRVGD + G+ATQCVQAKNVNK SPQTLSNLCLKINVKLGGINSILVPS+RP VF EPVIFLGAD THPPAGD  KPSIAAVVGSMDAHPSRYAATV VQ HRQE IQ+L++MV+ELLI FYKST  +KP RII YRDGVSEGQF +VL HEL AIREACIKLE  Y+PGITF+VVQKRHHTRLFC++KK+Q G+SGNIPAGTTVD  ITHPTEFDFYLCSH GIQGTSRPSHYHVLWDDN F +DE+Q LTYQLCHTYVRCTRSVSIPAPAYYAHLVAFRARYHLVEKE DSGEGS +SG S++R P AM RA+TVH++T KVMYFA
Sbjct:  133 FTCPRRPNLGREGRPIVLRANHFQVTMPRGYVHHYDINIQPDKCPRKVNREIIETMVHA--YSKIFGVLKPVFDGRNNLYTRDPLPIGNERLELEVTLPGEGKDRIFRVTIKWQAQVSLFNLEEALEGRTRQIPYDAILALDVVMRHLPSMTYTPVGRSFFSSPEGYYHPLGGGREVWFGFHQSVRPSQWKMMLNIDVSATAFYKAQPVIDFMCEVLDIRDINEQRKPLTDSQRVKFTKEIKGLKIEITHCGQMRRKYRVCNVTRRPAQMQSFPLQLENGQTVECTVAKYFLDKYRMKLRYPHLPCLQVGQEHKHTYLPLEVCNIVAGQRCIKKLTDMQTSTMIKATARSAPDREREINNLVKRADFNNDSYVQEFGLTISNSMMEVRGRVLPPPKLQYGGRVSTGLTGQQLFPPQNKVSLASPNQGVWDMRGKQFFTGVEIRIWAIACFAPQRTVREDALRNFTQQLQKISNDAGMPIIGQPCFCKYATGPDQVEPMFRYLKITFPGLQLVVVVLPGKTPVYAEVKRVGDTVLGMATQCVQAKNVNKTSPQTLSNLCLKINVKLGGINSILVPSIRPKVFNEPVIFLGADVTHPPAGDNKKPSIAAVVGSMDAHPSRYAATVRVQQHRQEIIQELSSMVRELLIMFYKSTGGYKPHRIILYRDGVSEGQFPHVLQHELTAIREACIKLEPEYRPGITFIVVQKRHHTRLFCAEKKEQSGKSGNIPAGTTVDVGITHPTEFDFYLCSHQGIQGTSRPSHYHVLWDDNHFDSDELQCLTYQLCHTYVRCTRSVSIPAPAYYAHLVAFRARYHLVEKEHDSGEGSHQSGCSEDRTPGAMARAITVHADTKKVMYFA 984

[Close]

BLAST of AGO-2 vs. Ensembl Fly
Match: AGO1 (gene:FBgn0262739 transcript:FBtr0087613)

HSP 1 Score: 1360.51 bits (3520), Expect = 0.000e+0
Identity = 644/854 (75.41%), Postives = 734/854 (85.95%), Query Frame = 1

Query:  277 FQPPSRPDQGTDGRTIQLKANHFEIVMPKGFLHHYDITITPEKCPRRVNRDIIQAMVNNMHYQKYFYNQKPVFDGRRNMYTREPLSIGKEKLELEVILPGEGKDRVFKVCLKHVSEVSLFALEEALQGRRQTIPAETVTALDVIMRHLPSMTYTPVGRSFFHNTGDYDNPLGGGREVWFGFHQSVRPSQWKMMLNIDVSATAFYKEQSVINFMFEVLEID--KDLKRPLTDSQRVKFTKEIKGLKVEINHCGPIKRKYRVCNVTRRSAQSQTFPLQSEQGQTIECTVTKYFQDRYGMKLQHPHLPCLQVGQEQKHTYLPLEVCNIVSGQRCIKKLTDMQTSTMIKATARSAPDREKEINNLVRRSNFNADPHLQIFGVSVNTRMADIQGRVIPAPKIQYGGRTK---------------AQATPQQGVWDMRGKQFFSGIEIKVWAIACFAPQRTVREDSLRTFTQQLQKISNDAGMPIVGQPCFCKYATGQDQVEPMFRYLKNSFSGLQLIVVVLPGKTPVYAEVKRVGDIIFGLATQCVQAKNVNKPSPQTLSNLCLKINVKLGGINSILVPSVRPAVFKEPVIFLGADFTHPPAGDKTKPSIAAVVGSMDAHPSRYAATVSVQPHRQETIQDLAAMVKELLIQFYKST-RFKPTRIIYYRDGVSEGQFLNVLNHELKAIREACIKLEMSYQPGITFVVVQKRHHTRLFCSDKKDQMGRSGNIPAGTTVDQIITHPTEFDFYLCSHAGIQGTSRPSHYHVLWDDNRFSADEIQTLTYQLCHTYVRCTRSVSIPAPAYYAHLVAFRARYHLVEKELDSGEGSQKSGNSDERNPTAMMRAVTVHSETLKVMYFA 2784
            F  P RP+ G +GR I L+ANHF++ MP+G++HHYDI I P+KCPR+VNR+II+ MV+   Y K F   KPVFDGR N+YTR+PL IG E+LELEV LPGEGKDR+F+V +K  ++VSLF LEEAL+GR + IP + + ALDV+MRHLPSMTYTPVGRSFF +   Y +PLGGGREVWFGFHQSVRPSQWKMMLNIDVSATAFYK Q VI+FM EVL+I    + ++PLTDSQRVKFTKEIKGLK+EI HCG ++RKYRVCNVTRR AQ Q+FPLQ E GQT+ECTV KYF D+Y MKL++PHLPCLQVGQE KHTYLPLEVCNIV+GQRCIKKLTDMQTSTMIKATARSAPDRE+EINNLV+R++FN D ++Q FG++++  M +++GRV+P PK+QYGGR                 + A+P QGVWDMRGKQFF+G+EI++WAIACFAPQRTVRED+LR FTQQLQKISNDAGMPI+GQPCFCKYATG DQVEPMFRYLK +F GLQL+VVVLPGKTPVYAEVKRVGD + G+ATQCVQAKNVNK SPQTLSNLCLKINVKLGGINSILVPS+RP VF EPVIFLGAD THPPAGD  KPSIAAVVGSMDAHPSRYAATV VQ HRQE IQ+L++MV+ELLI FYKST  +KP RII YRDGVSEGQF +VL HEL AIREACIKLE  Y+PGITF+VVQKRHHTRLFC++KK+Q G+SGNIPAGTTVD  ITHPTEFDFYLCSH GIQGTSRPSHYHVLWDDN F +DE+Q LTYQLCHTYVRCTRSVSIPAPAYYAHLVAFRARYHLVEKE DSGEGS +SG S++R P AM RA+TVH++T KVMYFA
Sbjct:  133 FTCPRRPNLGREGRPIVLRANHFQVTMPRGYVHHYDINIQPDKCPRKVNREIIETMVHA--YSKIFGVLKPVFDGRNNLYTRDPLPIGNERLELEVTLPGEGKDRIFRVTIKWQAQVSLFNLEEALEGRTRQIPYDAILALDVVMRHLPSMTYTPVGRSFFSSPEGYYHPLGGGREVWFGFHQSVRPSQWKMMLNIDVSATAFYKAQPVIDFMCEVLDIRDINEQRKPLTDSQRVKFTKEIKGLKIEITHCGQMRRKYRVCNVTRRPAQMQSFPLQLENGQTVECTVAKYFLDKYRMKLRYPHLPCLQVGQEHKHTYLPLEVCNIVAGQRCIKKLTDMQTSTMIKATARSAPDREREINNLVKRADFNNDSYVQEFGLTISNSMMEVRGRVLPPPKLQYGGRVSTGLTGQQLFPPQNKVSLASPNQGVWDMRGKQFFTGVEIRIWAIACFAPQRTVREDALRNFTQQLQKISNDAGMPIIGQPCFCKYATGPDQVEPMFRYLKITFPGLQLVVVVLPGKTPVYAEVKRVGDTVLGMATQCVQAKNVNKTSPQTLSNLCLKINVKLGGINSILVPSIRPKVFNEPVIFLGADVTHPPAGDNKKPSIAAVVGSMDAHPSRYAATVRVQQHRQEIIQELSSMVRELLIMFYKSTGGYKPHRIILYRDGVSEGQFPHVLQHELTAIREACIKLEPEYRPGITFIVVQKRHHTRLFCAEKKEQSGKSGNIPAGTTVDVGITHPTEFDFYLCSHQGIQGTSRPSHYHVLWDDNHFDSDELQCLTYQLCHTYVRCTRSVSIPAPAYYAHLVAFRARYHLVEKEHDSGEGSHQSGCSEDRTPGAMARAITVHADTKKVMYFA 984

[Close]

BLAST of AGO-2 vs. Ensembl Fly
Match: AGO1 (gene:FBgn0262739 transcript:FBtr0087614)

HSP 1 Score: 1360.13 bits (3519), Expect = 0.000e+0
Identity = 644/854 (75.41%), Postives = 734/854 (85.95%), Query Frame = 1

Query:  277 FQPPSRPDQGTDGRTIQLKANHFEIVMPKGFLHHYDITITPEKCPRRVNRDIIQAMVNNMHYQKYFYNQKPVFDGRRNMYTREPLSIGKEKLELEVILPGEGKDRVFKVCLKHVSEVSLFALEEALQGRRQTIPAETVTALDVIMRHLPSMTYTPVGRSFFHNTGDYDNPLGGGREVWFGFHQSVRPSQWKMMLNIDVSATAFYKEQSVINFMFEVLEID--KDLKRPLTDSQRVKFTKEIKGLKVEINHCGPIKRKYRVCNVTRRSAQSQTFPLQSEQGQTIECTVTKYFQDRYGMKLQHPHLPCLQVGQEQKHTYLPLEVCNIVSGQRCIKKLTDMQTSTMIKATARSAPDREKEINNLVRRSNFNADPHLQIFGVSVNTRMADIQGRVIPAPKIQYGGRTK---------------AQATPQQGVWDMRGKQFFSGIEIKVWAIACFAPQRTVREDSLRTFTQQLQKISNDAGMPIVGQPCFCKYATGQDQVEPMFRYLKNSFSGLQLIVVVLPGKTPVYAEVKRVGDIIFGLATQCVQAKNVNKPSPQTLSNLCLKINVKLGGINSILVPSVRPAVFKEPVIFLGADFTHPPAGDKTKPSIAAVVGSMDAHPSRYAATVSVQPHRQETIQDLAAMVKELLIQFYKST-RFKPTRIIYYRDGVSEGQFLNVLNHELKAIREACIKLEMSYQPGITFVVVQKRHHTRLFCSDKKDQMGRSGNIPAGTTVDQIITHPTEFDFYLCSHAGIQGTSRPSHYHVLWDDNRFSADEIQTLTYQLCHTYVRCTRSVSIPAPAYYAHLVAFRARYHLVEKELDSGEGSQKSGNSDERNPTAMMRAVTVHSETLKVMYFA 2784
            F  P RP+ G +GR I L+ANHF++ MP+G++HHYDI I P+KCPR+VNR+II+ MV+   Y K F   KPVFDGR N+YTR+PL IG E+LELEV LPGEGKDR+F+V +K  ++VSLF LEEAL+GR + IP + + ALDV+MRHLPSMTYTPVGRSFF +   Y +PLGGGREVWFGFHQSVRPSQWKMMLNIDVSATAFYK Q VI+FM EVL+I    + ++PLTDSQRVKFTKEIKGLK+EI HCG ++RKYRVCNVTRR AQ Q+FPLQ E GQT+ECTV KYF D+Y MKL++PHLPCLQVGQE KHTYLPLEVCNIV+GQRCIKKLTDMQTSTMIKATARSAPDRE+EINNLV+R++FN D ++Q FG++++  M +++GRV+P PK+QYGGR                 + A+P QGVWDMRGKQFF+G+EI++WAIACFAPQRTVRED+LR FTQQLQKISNDAGMPI+GQPCFCKYATG DQVEPMFRYLK +F GLQL+VVVLPGKTPVYAEVKRVGD + G+ATQCVQAKNVNK SPQTLSNLCLKINVKLGGINSILVPS+RP VF EPVIFLGAD THPPAGD  KPSIAAVVGSMDAHPSRYAATV VQ HRQE IQ+L++MV+ELLI FYKST  +KP RII YRDGVSEGQF +VL HEL AIREACIKLE  Y+PGITF+VVQKRHHTRLFC++KK+Q G+SGNIPAGTTVD  ITHPTEFDFYLCSH GIQGTSRPSHYHVLWDDN F +DE+Q LTYQLCHTYVRCTRSVSIPAPAYYAHLVAFRARYHLVEKE DSGEGS +SG S++R P AM RA+TVH++T KVMYFA
Sbjct:   99 FTCPRRPNLGREGRPIVLRANHFQVTMPRGYVHHYDINIQPDKCPRKVNREIIETMVHA--YSKIFGVLKPVFDGRNNLYTRDPLPIGNERLELEVTLPGEGKDRIFRVTIKWQAQVSLFNLEEALEGRTRQIPYDAILALDVVMRHLPSMTYTPVGRSFFSSPEGYYHPLGGGREVWFGFHQSVRPSQWKMMLNIDVSATAFYKAQPVIDFMCEVLDIRDINEQRKPLTDSQRVKFTKEIKGLKIEITHCGQMRRKYRVCNVTRRPAQMQSFPLQLENGQTVECTVAKYFLDKYRMKLRYPHLPCLQVGQEHKHTYLPLEVCNIVAGQRCIKKLTDMQTSTMIKATARSAPDREREINNLVKRADFNNDSYVQEFGLTISNSMMEVRGRVLPPPKLQYGGRVSTGLTGQQLFPPQNKVSLASPNQGVWDMRGKQFFTGVEIRIWAIACFAPQRTVREDALRNFTQQLQKISNDAGMPIIGQPCFCKYATGPDQVEPMFRYLKITFPGLQLVVVVLPGKTPVYAEVKRVGDTVLGMATQCVQAKNVNKTSPQTLSNLCLKINVKLGGINSILVPSIRPKVFNEPVIFLGADVTHPPAGDNKKPSIAAVVGSMDAHPSRYAATVRVQQHRQEIIQELSSMVRELLIMFYKSTGGYKPHRIILYRDGVSEGQFPHVLQHELTAIREACIKLEPEYRPGITFIVVQKRHHTRLFCAEKKEQSGKSGNIPAGTTVDVGITHPTEFDFYLCSHQGIQGTSRPSHYHVLWDDNHFDSDELQCLTYQLCHTYVRCTRSVSIPAPAYYAHLVAFRARYHLVEKEHDSGEGSHQSGCSEDRTPGAMARAITVHADTKKVMYFA 950

[Close]

BLAST of AGO-2 vs. Ensembl Fly
Match: AGO2 (gene:FBgn0087035 transcript:FBtr0331933)

HSP 1 Score: 323.168 bits (827), Expect = 2.593e-96
Identity = 243/790 (30.76%), Postives = 379/790 (47.97%), Query Frame = 1

Query:  373 HHYDITITPEKCPRRVNRDIIQAMVNNMHYQKYFYNQKP----VFDGRRNMYTREPLSIGKEKLELEVILPGEGKDRVFKVCLKHV--SEVSLFALEEALQGRRQTIPAETVTALDVIMRHLPSMTYTPVGRSFFHNTGDYDN--PLGGGREVWFGFHQSVRPSQWKMMLNIDVSATAFYKEQSVINFMFEVLEIDKDLKRPLTDSQRVKFTKE-----IKGLKV-----EINHCGPIKRKYRVCNVTRRSAQSQTFPLQSEQGQTIECTVTKYFQDRYGMKLQHPHLPCLQVGQEQKHTYLPLEVCNIVSGQRCIKKLTDMQTSTMIKATARSAPDREKEINNLVRRSNFNADPHLQIFGVSVNTRMADIQGRVIPAPKIQYGGRTKAQATPQQGVWDMRGKQFFSGIEIKVWAIACFAPQRTVREDSLRTFTQQLQKISNDAGMPIVGQPCFCKYATGQDQVEPMF----RYLKNSFSGLQ-----LIVVVLPGKTPVYAEVKRVGDIIFGLATQCVQAKNVN-KPSPQTLSNLCLKINVKLGGINSILVPSVRPAVFKEPVIFLGADFTHPPAGDKTKPSIAAVVGSMDAHPSRYAATVSVQPHRQETIQDLAAMVKELLIQFYKSTRFKPTRIIYYRDGVSEGQFLNVLNHELKAIREACIKLEMSYQPGITFVVVQKRHHTRLFCSDKKDQMGRSGNIPAGTTVDQIITHPTEFDFYLCSHAGIQGTSRPSHYHVLWDDNRFSADEIQTLTYQLCHTYVRCTRSVSIPAPAYYAHLVAFRARYHL 2658
            +HYD+ I PE+ P++  R   QA      ++++  +Q       +DG+ + Y+ + L +  +  E+ V     G+   + + +K    S + L +L   +  R    P   +  ++V++          VGRSFF    D +N   L  G E   G +Q+      +  LN+D+S  +F     +I ++         LK  + ++  + +++      ++G+ V     +     P  R YRV  ++R  A S+TF      G+ +  T+  YF  R    L+ P L CL VG   K   LP+E+C+I  GQ   +K    Q + MIK  A S   R+++I NL++    N DP +  FG+ +      +  RV+  P+++Y   +K     + G W M G +F   +E K  A  C       R      +TQ      ND G  I+ Q      +   D     F    R L   F+ L+     L +V++P     Y  +K+  ++  G+ TQC++   V  K + QT+ N+ LKIN KL GIN  +    R  + K   +++GAD THP    +  PS+  V  S D + + Y     +Q    E I+D+ ++  E L  + +     P  IIYYRDGVS+GQF  + N EL+ I++AC K+    +P I  V+V KRHHTR F S       +  N+  GT VD+ I HP E  F++ SH  IQGT++P+ Y+V+ +      D +Q LTY LCH + RC RSVS PAPAY AHLVA R R +L
Sbjct:    6 YHYDVKIMPER-PKKFYR---QA------FEQFRVDQLGGAVLAYDGKASCYSVDKLPLNSQNPEVTVT-DRNGRTLRYTIEIKETGDSTIDLKSLTTYMNDRIFDKPMRAMQCVEVVLASPCHNKAIRVGRSFF-KMSDPNNRHELDDGYEALVGLYQAFMLGD-RPFLNVDISHKSFPISMPMIEYLERF-----SLKAKINNTTNLDYSRRFLEPFLRGINVVYTPPQSFQSAP--RVYRVNGLSRAPASSETF---EHDGKKV--TIASYFHSR-NYPLKFPQLHCLNVGSSIKSILLPIELCSIEEGQALNRKDGATQVANMIKYAATSTNVRKRKIMNLLQYFQHNLDPTISRFGIRIANDFIVVSTRVLSPPQVEY--HSKRFTMVKNGSWRMDGMKF---LEPKPKAHKCAVLYCDPRSGRKMNYTQL-----NDFGNLIISQGKAVNISLDSDVTYRPFTDDERSLDTIFADLKRSQHDLAIVIIPQFRISYDTIKQKAELQHGILTQCIKQFTVERKCNNQTIGNILLKINSKLNGINHKIKDDPRLPMMKN-TMYIGADVTHPSPDQREIPSVVGVAASHDPYGASYNMQYRLQRGALEEIEDMFSITLEHLRVYKEYRNAYPDHIIYYRDGVSDGQFPKIKNEELRCIKQACDKV--GCKPKICCVIVVKRHHTRFFPSGDVTTSNKFNNVDPGTVVDRTIVHPNEMQFFMVSHQAIQGTAKPTRYNVIENTGNLDIDLLQQLTYNLCHMFPRCNRSVSYPAPAYLAHLVAARGRVYL 756

[Close]

BLAST of AGO-2 vs. Ensembl Zebrafish
Match: ago2 (argonaute RISC catalytic component 2 [Source:ZFIN;Acc:ZDB-GENE-110606-6])

HSP 1 Score: 1297.34 bits (3356), Expect = 0.000e+0
Identity = 628/892 (70.40%), Postives = 719/892 (80.61%), Query Frame = 1

Query:  115 MNPLGAPGQPPNTSVPAIIGSTQLSSNISSGPSPPQLPTXXXXXXXXXXXXXVYFQPPSRPDQGTDGRTIQLKANHFEIVMPKGFLHHYDITITPEKCPRRVNRDIIQAMVNNMHYQKYFYNQKPVFDGRRNMYTREPLSIGKEKLELEVILPGEGKDRVFKVCLKHVSEVSLFALEEALQGRRQTIPAETVTALDVIMRHLPSMTYTPVGRSFFHNTGDYDNPLGGGREVWFGFHQSVRPSQWKMMLNIDVSATAFYKEQSVINFMFEVLEID--KDLKRPLTDSQRVKFTKEIKGLKVEINHCGPIKRKYRVCNVTRRSAQSQTFPLQSEQGQTIECTVTKYFQDRYGMKLQHPHLPCLQVGQEQKHTYLPLEVCNIVSGQRCIKKLTDMQTSTMIKATARSAPDREKEINNLVRRSNFNADPHLQIFGVSVNTRMADIQGRVIPAPKIQYGGRTKAQATPQQGVWDMRGKQFFSGIEIKVWAIACFAPQRTVREDSLRTFTQQLQKISNDAGMPIVGQPCFCKYATGQDQVEPMFRYLKNSFSGLQLIVVVLPGKTPVYAEVKRVGDIIFGLATQCVQAKNVNKPSPQTLSNLCLKINVKLGGINSILVPSVRPAVFKEPVIFLGADFTHPPAGDKTKPSIAAVVGSMDAHPSRYAATVSVQPHRQETIQDLAAMVKELLIQFYKSTRFKPTRIIYYRDGVSEGQFLNVLNHELKAIREACIKLEMSYQPGITFVVVQKRHHTRLFCSDKKDQMGRSGNIPAGTTVDQIITHPTEFDFYLCSHAGIQGTSRPSHYHVLWDDNRFSADEIQTLTYQLCHTYVRCTRSVSIPAPAYYAHLVAFRARYHLVEKELDSGEGSQKSGNSDERNPTAMMRAVTVHSETLKVMYFA 2784
            M P+GA G     +     G     S++S+  SPP                   F+PP RPD GT GRTI+L+AN FE+ +PK  ++HY+I I PEKCPRRVNR+I++ MV +   Q  F ++KPV+DGR+N+YT  PL IG++K+ELEV +PGEGKDR FKV +K +S VSL AL EAL GR   IP ET+ ALDV+MRHLPSM YTPVGRSFF  +    NPLGGGREVWFGFHQSVRPS WKMMLNIDVSATAFYK Q VI FM EVL+    ++ ++PLTDSQRVKFTKEIKGLKVEI HCG +KRKYRVCNVTRR A  QTFPLQ E GQTIECTV +YF+D+Y + L++PHLPCLQVGQEQKHTYLPLEVCNIV+GQRCIKKLTD QTSTMI+ATARSAPDR+ EI+ L+R +NFN DP+++ FGV V   M ++ GRV+ AP I YGGR KA ATP QGVWDMR KQF +GIEIKVWAIACFAPQR   E  L+ FT QL+KIS DAGMPI GQPCFCKYA G D VEPMF++LK ++ GLQL+VV+LPGKTPVYAEVKRVGD + G+ATQCVQ KNV K +PQTLSNLCLKINVKLGG+N+IL+P  RP VF++PVIFLGAD THPPAGD  KPSIAAVVGSMDAHPSRY ATV VQ HRQ+ IQDLA MV+ELLIQFYKSTRFKPTRIIYYRDG+SEGQF  VL HEL AIREACIKLE  YQPGITFVVVQKRHHTRLFC D+ +++G+SGNIPAGTTVD  ITHP EFDFYLCSHAGIQGTSRPSHYHVLWDDN F++DE+Q LTYQLCHTYVRCTRSVSIPAPAYYAHLVAFRARYHLV+KE DS EGS  SG S+ R+  A+ +AV +H +TL+ MYFA
Sbjct:    1 MYPIGAAG-----ATELFQGRPSSGSDVSAPASPP-------------APQEYVFKPPQRPDFGTMGRTIKLQANFFEMEIPKLEVYHYEIDIKPEKCPRRVNREIVEHMVQHFKTQ-IFGDRKPVYDGRKNLYTAMPLPIGRDKVELEVTIPGEGKDRSFKVAIKWMSCVSLQALHEALSGRLPNIPFETIQALDVVMRHLPSMRYTPVGRSFFTPSEGCSNPLGGGREVWFGFHQSVRPSLWKMMLNIDVSATAFYKAQPVIEFMCEVLDFKSIEEQQKPLTDSQRVKFTKEIKGLKVEITHCGQMKRKYRVCNVTRRPASHQTFPLQQENGQTIECTVAQYFKDKYKLVLRYPHLPCLQVGQEQKHTYLPLEVCNIVAGQRCIKKLTDNQTSTMIRATARSAPDRQDEISKLMRSANFNTDPYVREFGVMVRDDMTEVNGRVLQAPSILYGGRNKAIATPVQGVWDMRNKQFHTGIEIKVWAIACFAPQRQCTELLLKAFTDQLRKISRDAGMPIQGQPCFCKYAQGADSVEPMFKHLKYTYQGLQLVVVILPGKTPVYAEVKRVGDTVLGMATQCVQVKNVQKTTPQTLSNLCLKINVKLGGVNNILLPQGRPLVFQQPVIFLGADVTHPPAGDGKKPSIAAVVGSMDAHPSRYCATVRVQQHRQDIIQDLATMVRELLIQFYKSTRFKPTRIIYYRDGISEGQFNQVLQHELLAIREACIKLEKDYQPGITFVVVQKRHHTRLFCMDRNERVGKSGNIPAGTTVDTKITHPFEFDFYLCSHAGIQGTSRPSHYHVLWDDNHFTSDELQVLTYQLCHTYVRCTRSVSIPAPAYYAHLVAFRARYHLVDKEHDSAEGSHTSGQSNGRDQQALAKAVQIHQDTLRTMYFA 873

[Close]

BLAST of AGO-2 vs. Ensembl Zebrafish
Match: ago1 (argonaute RISC component 1 [Source:ZFIN;Acc:ZDB-GENE-110606-3])

HSP 1 Score: 1259.97 bits (3259), Expect = 0.000e+0
Identity = 601/868 (69.24%), Postives = 708/868 (81.57%), Query Frame = 1

Query:  187 SSNISSGPSPPQLPTXXXXXXXXXXXXXVYFQPPSRPDQGTDGRTIQLKANHFEIVMPKGFLHHYDITITPEKCPRRVNRDIIQAMVNNMHYQKYFYNQKPVFDGRRNMYTREPLSIGKEKLELEVILPGEGKDRVFKVCLKHVSEVSLFALEEALQGRRQTIPAETVTALDVIMRHLPSMTYTPVGRSFFHNTGDYDNPLGGGREVWFGFHQSVRPSQWKMMLNIDVSATAFYKEQSVINFMFEVLEIDKDLKRP--LTDSQRVKFTKEIKGLKVEINHCGPIKRKYRVCNVTRRSAQSQTFPLQSEQGQTIECTVTKYFQDRYGMKLQHPHLPCLQVGQEQKHTYLPLEVCNIVSGQRCIKKLTDMQTSTMIKATARSAPDREKEINNLVRRSNFNADPHLQIFGVSVNTRMADIQGRVIPAPKIQYGGRTKAQATPQQGVWDMRGKQFFSGIEIKVWAIACFAPQRTVREDSLRTFTQQLQKISNDAGMPIVGQPCFCKYATGQDQVEPMFRYLKNSFSGLQLIVVVLPGKTPVYAEVKRVGDIIFGLATQCVQAKNVNKPSPQTLSNLCLKINVKLGGINSILVPSVRPAVFKEPVIFLGADFTHPPAGDKTKPSIAAVVGSMDAHPSRYAATVSVQPHRQETIQDLAAMVKELLIQFYKSTRFKPTRIIYYRDGVSEGQFLNVLNHELKAIREACIKLEMSYQPGITFVVVQKRHHTRLFCSDKKDQMGRSGNIPAGTTVDQIITHPTEFDFYLCSHAGIQGTSRPSHYHVLWDDNRFSADEIQTLTYQLCHTYVRCTRSVSIPAPAYYAHLVAFRARYHLVEKELDSGEGSQKSGNSDERNPTAMMRAVTVHSETLKVMYFA 2784
            S  +  GP PP L                 FQ P RP  GT G+ I+L AN+FE+ +PK  + HY++ I P+KCPRRVNR++++ MV +   Q  F ++KPV+DG++N+YT   L IG EK++ EV +PGEGKDR+FKV ++ +++VS   L+E L   R  +P E+V ALDV MRHL SM YTPVGRSFF     Y +PLGGGREVWFGFHQSVRP+ WKMMLNIDVSATAFYK Q VI FM EVL+I    ++P  LTDSQRV+FTKEIKGLKVE+ HCG +KRKYRVCNVTRR A  QTFPLQ E GQT+ECTV +YF+ +Y ++L++PHLPCLQVGQEQKHTYLPLEVCNIV+GQRCIKKLTD QTSTMIKATARSAPDR++EI+ L++ +NFN DP++Q FG+ V   M ++ GRV+PAP +QYGGR +A ATP QGVWDMRGKQF++GIEIKVWAIACFAPQ+  RE+ L+ FT QL+KIS DAGMPI GQPCFCKYA G D VEPMFR+LKN++SGLQLI+V+LPGKTPVYAEVKRVGD + G+ATQCVQ KNV K SPQTLSNLCLKINVKLGGIN+ILVP  R AVF++PVIFLGAD THPPAGD  KPSI AVVGSMDAHPSRY ATV VQ  RQE I+DL+ MV+ELLIQFYKSTRFKPTRII+YRDGV EGQ   +L++EL AIR+ACIKLE  YQPGIT++VVQKRHHTRLFC+DK +++G+SGNIPAGTTVD  ITHP EFDFYLCSHAGIQGTSRPSHY+VLWDDNRF+ADE+Q LTYQLCHTYVRCTRSVSIPAPAYYA LVAFRARYHLV+KE DSGEGS  SG S+ R+P A+ +AV +H ++L+ MYFA
Sbjct:    6 SGAVPVGPYPPPLQQV--------------FQAPRRPGMGTVGKPIKLLANYFEVEIPKMDVFHYEVDIKPDKCPRRVNREVVEYMVQHFKPQ-LFGDRKPVYDGKKNIYTVLALPIGSEKVDFEVTIPGEGKDRIFKVSIRWLAKVSWRLLQETLVSGRLQVPLESVQALDVAMRHLASMRYTPVGRSFFSPPEGYYHPLGGGREVWFGFHQSVRPAMWKMMLNIDVSATAFYKAQPVIEFMCEVLDIRNIDEQPKTLTDSQRVRFTKEIKGLKVEVTHCGQMKRKYRVCNVTRRPASHQTFPLQLESGQTVECTVAQYFKQKYNLQLKYPHLPCLQVGQEQKHTYLPLEVCNIVAGQRCIKKLTDNQTSTMIKATARSAPDRQEEISRLMKNANFNLDPYIQEFGIKVKDDMTEVTGRVLPAPILQYGGRNRAIATPNQGVWDMRGKQFYNGIEIKVWAIACFAPQKQCREEVLKNFTDQLRKISKDAGMPIQGQPCFCKYAQGADSVEPMFRHLKNTYSGLQLIIVILPGKTPVYAEVKRVGDTLLGMATQCVQVKNVVKTSPQTLSNLCLKINVKLGGINNILVPHQRSAVFQQPVIFLGADVTHPPAGDGKKPSITAVVGSMDAHPSRYCATVRVQRPRQEIIEDLSYMVRELLIQFYKSTRFKPTRIIFYRDGVPEGQLPQILHYELLAIRDACIKLEKDYQPGITYIVVQKRHHTRLFCADKSERIGKSGNIPAGTTVDTSITHPFEFDFYLCSHAGIQGTSRPSHYYVLWDDNRFTADELQILTYQLCHTYVRCTRSVSIPAPAYYARLVAFRARYHLVDKEHDSGEGSHVSGQSNGRDPQALAKAVQIHHDSLRTMYFA 858

[Close]

BLAST of AGO-2 vs. Ensembl Zebrafish
Match: ago3b (argonaute RISC catalytic component 3b [Source:NCBI gene;Acc:568159])

HSP 1 Score: 1238.4 bits (3203), Expect = 0.000e+0
Identity = 592/847 (69.89%), Postives = 693/847 (81.82%), Query Frame = 1

Query:  277 FQPPSRPDQGTDGRTIQLKANHFEIVMPKGFLHHYDITITPEKCPRRVNRDIIQAMVNNMHYQKYFYNQKPVFDGRRNMYTREPLSIGKEKLELEVILPGEG-KDRVFKVCLKHVSEVSLFALEEALQGRRQTIPAET--------VTALDVIMRHLPSMTYTPVGRSFFHNTGDYDNPLGGGREVWFGFHQSVRPSQWKMMLNIDVSATAFYKEQSVINFMFEVLEIDK--DLKRPLTDSQRVKFTKEIKGLKVEINHCGPIKRKYRVCNVTRRSAQSQTFPLQSEQGQTIECTVTKYFQDRYGMKLQHPHLPCLQVGQEQKHTYLPLEVCNIVSGQRCIKKLTDMQTSTMIKATARSAPDREKEINNLVRRSNFNADPHLQIFGVSVNTRMADIQGRVIPAPKIQYGGRTKAQATPQQGVWDMRGKQFFSGIEIKVWAIACFAPQRTVREDSLRTFTQQLQKISNDAGMPIVGQPCFCKYATGQDQVEPMFRYLKNSFSGLQLIVVVLPGKTPVYAEVKRVGDIIFGLATQCVQAKNVNKPSPQTLSNLCLKINVKLGGINSILVPSVRPAVFKEPVIFLGADFTHPPAGDKTKPSIAAVVGSMDAHPSRYAATVSVQPHRQETIQDLAAMVKELLIQFYKSTRFKPTRIIYYRDGVSEGQFLNVLNHELKAIREACIKLEMSYQPGITFVVVQKRHHTRLFCSDKKDQMGRSGNIPAGTTVDQIITHPTEFDFYLCSHAGIQGTSRPSHYHVLWDDNRFSADEIQTLTYQLCHTYVRCTRSVSIPAPAYYAHLVAFRARYHLVEKELDSGEGSQKSGNSDERNPTAMMRAVTVHSETLKVMYFA 2784
            F  P RP  GT G+ I+L AN F++ +PK  ++ YD+ I PEKCPRRVNR+++ +MV +      F +++PV+DG++++YT +PL +    ++L+V LPGEG KDR+FKV +K VS VS   L E L GR    P E         V A+DV++RHLPSM YTPVGRSFF +   YD+PLGGGREVWFGFHQSVRP+ WKMMLNIDVSATAFYK Q VI FM EVL+I    +  RPLTDS RVKFTKEIKGLKVE+ HCG ++RKYRVCNVTRR A  QTFPLQ E GQT+E TV +YF+++Y ++L++PHLPCLQVGQEQKHTYLPLEVCNIV+GQRCIKKLTD QTSTMIKATARSAPDR++EI+ LVR +N+N+DP +Q F   V   MA++ GRV+PAP +QYGGR +  ATP  GVWDMRGKQF +G+EIK+WAIACFA QR  RE+ L+ FT QL+KIS DAGMPI GQPCFCKYA G D VEPMFR+LKN+++GLQLI+V+LPGKTPVYAEVKRVGD + G+ATQCVQ KNV K SPQTLSNLCLKINVKLGGIN+ILVP  RP+VF++PVIFLGAD THPPAGD  KPSIAAVVGSMDAHPSRY ATV VQ  RQE IQDLA+MV+ELLIQFYKST +KPTRII+YRDGVSEGQF  VL +EL AIREACI LE  YQPGIT++VVQKRHHTRLFC+D+ +++GRSGNIPAGTTVD  ITHP EFDFYLCSHAGIQGTSRPSHY+VLWDDN F+ADE Q LTYQLCHTYVRCTRSVSIPAPAYYAHLVAFRARYHLV+KE DS EGS  SG S+ R+P A+ +AV +H +TL+ MYFA
Sbjct:   15 FSVPRRPGYGTMGKPIKLLANCFQVDIPKMDVYLYDVDIKPEKCPRRVNREVVDSMVQHFKV-TIFGDRRPVYDGKKSLYTAQPLPVASAGVDLDVTLPGEGGKDRIFKVTIKFVSLVSWHMLHEVLTGRSTPDPLELDKPISTNPVHAVDVVLRHLPSMRYTPVGRSFFSSPEGYDHPLGGGREVWFGFHQSVRPAMWKMMLNIDVSATAFYKAQPVIQFMCEVLDIHNIDEQPRPLTDSHRVKFTKEIKGLKVEVTHCGTMRRKYRVCNVTRRPASHQTFPLQLENGQTVERTVAQYFREKYNLQLKYPHLPCLQVGQEQKHTYLPLEVCNIVAGQRCIKKLTDNQTSTMIKATARSAPDRQEEISRLVRSANYNSDPFVQEFQFRVRDEMAEVTGRVLPAPMLQYGGRNRTVATPSHGVWDMRGKQFHTGVEIKMWAIACFATQRQCREEVLKGFTDQLRKISKDAGMPIQGQPCFCKYAQGADNVEPMFRHLKNTYAGLQLIIVILPGKTPVYAEVKRVGDTLLGMATQCVQVKNVVKTSPQTLSNLCLKINVKLGGINNILVPHQRPSVFQQPVIFLGADVTHPPAGDGKKPSIAAVVGSMDAHPSRYCATVRVQRPRQEVIQDLASMVRELLIQFYKSTHYKPTRIIFYRDGVSEGQFRQVLYYELLAIREACISLEKEYQPGITYIVVQKRHHTRLFCADRAERVGRSGNIPAGTTVDTDITHPYEFDFYLCSHAGIQGTSRPSHYYVLWDDNCFTADEFQLLTYQLCHTYVRCTRSVSIPAPAYYAHLVAFRARYHLVDKEHDSAEGSHVSGQSNGRDPQALAKAVQIHHDTLRTMYFA 860

[Close]

BLAST of AGO-2 vs. Ensembl Zebrafish
Match: ago4 (argonaute RISC component 4 [Source:ZFIN;Acc:ZDB-GENE-030131-5357])

HSP 1 Score: 1235.71 bits (3196), Expect = 0.000e+0
Identity = 593/850 (69.76%), Postives = 690/850 (81.18%), Query Frame = 1

Query:  277 FQPPSRPDQGTDGRTIQLKANHFEIVMPKGFLHHYDITITPEKCPRRVNRDIIQAMVNNMHYQKYFYNQKPVFDGRRNMYTREPLSIGKEKLELEVILPGEGKDRVFKVCLKHVSEVSLFALEEALQGRRQTIPAETVTALDVIMRHLPSMTYTPVGRSFFHNTGDYDNPLGGGREVWFGFHQSVRPSQWKMMLNIDVSATAFYKEQSVINFMFEVLEIDK--DLKRPLTDSQRVKFTKEIKGLKVEINHCGPIKRKYRVCNVTRRSAQSQTFPLQSEQGQTIECTVTKYFQDRYGMKLQHPHLPCLQVGQEQKHTYLPLEVCNIVSGQRCIKKLTDMQTSTMIKATARSAPDREKEINNLVRRSNF--NADPHLQIFGVSVNTRMADIQGRVIPAPKIQYGGRTKAQATPQQGVWDMRGKQFFSGIEIKVWAIACFAPQRTVREDSLRTFTQQLQKISNDAGMPIVGQPCFCKYATGQDQVEPMFRYLKNSFSGLQLIVVVLPGKTPVYAEVKRVGDIIFGLATQCVQAKNVNKPSPQTLSNLCLKINVKLGGINSILVPSVRPAVFKEPVIFLGADFTHPPAGDKTKPSIAAVVGSMDAHPSRYAATVSVQPHR----------QETIQDLAAMVKELLIQFYKSTRFKPTRIIYYRDGVSEGQFLNVLNHELKAIREACIKLEMSYQPGITFVVVQKRHHTRLFCSDKKDQMGRSGNIPAGTTVDQIITHPTEFDFYLCSHAGIQGTSRPSHYHVLWDDNRFSADEIQTLTYQLCHTYVRCTRSVSIPAPAYYAHLVAFRARYHLVEKELDSGEGSQKSGNSDERNPTAMMRAVTVHSETLKVMYFA 2784
            FQPP RP  GT G+ I+L ANHF++ +PK  ++HYDI I PEK PRRVNR+++  MV +   Q  F +++P +DG+RNMYT  PL IG+++++LEV LPGEGKD+ FKV L+ VS VSL  L EAL G    +P ++V ALDVI RHLPSM YTPVGRSFF     Y +PLGGGREVWFGFHQSVRP+ W MMLNIDVSATAFY+ Q VI FM EVL+I    +  +PLTDSQRVKFTKEI+GLKVE+ HCG +KRKYRVCNVTRR A  QTFPLQ E GQ +ECTV +YF+ +Y ++L++PHLPCLQVGQEQKHTYLPLEVCNIV+GQRCIKKLTD QTSTMIKATARSAPDR++EI+ LV+ ++     DP+L+ FG+ V+  M ++ GRV+PAP +QYGGR K  ATP QGVWDMRGKQF++GIEIKVWA+ACFAPQ+  RED L++FT QL+KIS DAGMPI GQPCFCKYA G D VEPMF++LK S+ GLQLIVV+LPGKTPVYAEVKRVGD + G+ATQCVQ KNV K SPQTLSNLCLKIN KLGGIN++LVP  RP+VF++PVIFLGAD THPPAGD  KPSIAAVVGSMD HPSRY ATV VQ  R          QE IQDL  MV+ELLIQFYKSTRFKPTRIIYYR GVSEGQ   V   EL AIR+ACI LE  Y+PGIT++VVQKRHHTRLFCSDK +++G+SGN+PAGTTVD  ITHP+EFDFYLCSHAGIQGTSRPSHYHVLWDDN F+ADE+Q LTYQLCHTYVRCTRSVSIPAPAYYA LVAFRARYHLV+K+ DS EGS  SG S+ R+P A+ +AV +H +T   MYFA
Sbjct:   15 FQPPRRPGLGTVGKPIRLLANHFQVQIPKIDVYHYDIDIKPEKRPRRVNREVVDTMVRHFKMQ-IFGDRQPGYDGKRNMYTAHPLPIGRDRVDLEVTLPGEGKDQTFKVSLQWVSVVSLQMLLEALSGHLNEVPEDSVQALDVITRHLPSMRYTPVGRSFFSPPEGYYHPLGGGREVWFGFHQSVRPAMWNMMLNIDVSATAFYRAQPVIEFMCEVLDIQNINEQTKPLTDSQRVKFTKEIRGLKVEVTHCGQMKRKYRVCNVTRRPASHQTFPLQLENGQAMECTVAQYFKQKYSLQLKYPHLPCLQVGQEQKHTYLPLEVCNIVAGQRCIKKLTDNQTSTMIKATARSAPDRQEEISRLVKSNSMVGGPDPYLKEFGIVVHNDMTEVTGRVLPAPMLQYGGRNKTVATPNQGVWDMRGKQFYAGIEIKVWAVACFAPQKQCREDLLKSFTDQLRKISKDAGMPIQGQPCFCKYAQGADSVEPMFKHLKMSYVGLQLIVVILPGKTPVYAEVKRVGDTLLGMATQCVQVKNVVKTSPQTLSNLCLKINAKLGGINNVLVPHQRPSVFQQPVIFLGADVTHPPAGDGKKPSIAAVVGSMDGHPSRYCATVRVQTSRQDLSQEQLFSQEVIQDLTNMVRELLIQFYKSTRFKPTRIIYYRGGVSEGQMKQVAWPELIAIRKACISLEEDYRPGITYIVVQKRHHTRLFCSDKAERVGKSGNVPAGTTVDSTITHPSEFDFYLCSHAGIQGTSRPSHYHVLWDDNCFTADELQLLTYQLCHTYVRCTRSVSIPAPAYYARLVAFRARYHLVDKDHDSAEGSHVSGQSNGRDPQALAKAVQIHYDTQHTMYFA 863

[Close]

BLAST of AGO-2 vs. Ensembl Zebrafish
Match: ago3b (argonaute RISC catalytic component 3b [Source:NCBI gene;Acc:568159])

HSP 1 Score: 1233.39 bits (3190), Expect = 0.000e+0
Identity = 592/854 (69.32%), Postives = 694/854 (81.26%), Query Frame = 1

Query:  277 FQPPSRPDQGTDGRTIQLKANHFEIVMPKGFLHHYDITITPEKCPRRVNRDIIQAMVNNMHYQKYFYNQKPVFDGRRNMYTREPLSIGKEKLELEVILPGEG-KDRVFKVCLKHVSEVSLFALEEALQGRRQTIPAET--------VTALDVIMRHLPSMTYTPVGRSFFHNTGDYDNPLGGGREVWFGFHQSVRPSQWKMMLNIDVSATAFYKEQSVINFMFEVLEIDK--DLKRPLTDSQRVKFTKEIKGLKVEINHCGPIKRKYRVCNVTRRSAQSQTFPLQSEQGQTIECTVTKYFQDRYGMKLQHPHLPCLQVGQEQKHTYLPLEVCNIVSGQRCIKKLTDMQTSTMIKATARSAPDREKEINNLVRRSNFNADPHLQIFGVSVNTRMADIQGRVIPAPKIQYGGRTKAQ-------ATPQQGVWDMRGKQFFSGIEIKVWAIACFAPQRTVREDSLRTFTQQLQKISNDAGMPIVGQPCFCKYATGQDQVEPMFRYLKNSFSGLQLIVVVLPGKTPVYAEVKRVGDIIFGLATQCVQAKNVNKPSPQTLSNLCLKINVKLGGINSILVPSVRPAVFKEPVIFLGADFTHPPAGDKTKPSIAAVVGSMDAHPSRYAATVSVQPHRQETIQDLAAMVKELLIQFYKSTRFKPTRIIYYRDGVSEGQFLNVLNHELKAIREACIKLEMSYQPGITFVVVQKRHHTRLFCSDKKDQMGRSGNIPAGTTVDQIITHPTEFDFYLCSHAGIQGTSRPSHYHVLWDDNRFSADEIQTLTYQLCHTYVRCTRSVSIPAPAYYAHLVAFRARYHLVEKELDSGEGSQKSGNSDERNPTAMMRAVTVHSETLKVMYFA 2784
            F  P RP  GT G+ I+L AN F++ +PK  ++ YD+ I PEKCPRRVNR+++ +MV +      F +++PV+DG++++YT +PL +    ++L+V LPGEG KDR+FKV +K VS VS   L E L GR    P E         V A+DV++RHLPSM YTPVGRSFF +   YD+PLGGGREVWFGFHQSVRP+ WKMMLNIDVSATAFYK Q VI FM EVL+I    +  RPLTDS RVKFTKEIKGLKVE+ HCG ++RKYRVCNVTRR A  QTFPLQ E GQT+E TV +YF+++Y ++L++PHLPCLQVGQEQKHTYLPLEVCNIV+GQRCIKKLTD QTSTMIKATARSAPDR++EI+ LVR +N+N+DP +Q F   V   MA++ GRV+PAP +QYGGR  ++       ATP  GVWDMRGKQF +G+EIK+WAIACFA QR  RE+ L+ FT QL+KIS DAGMPI GQPCFCKYA G D VEPMFR+LKN+++GLQLI+V+LPGKTPVYAEVKRVGD + G+ATQCVQ KNV K SPQTLSNLCLKINVKLGGIN+ILVP  RP+VF++PVIFLGAD THPPAGD  KPSIAAVVGSMDAHPSRY ATV VQ  RQE IQDLA+MV+ELLIQFYKST +KPTRII+YRDGVSEGQF  VL +EL AIREACI LE  YQPGIT++VVQKRHHTRLFC+D+ +++GRSGNIPAGTTVD  ITHP EFDFYLCSHAGIQGTSRPSHY+VLWDDN F+ADE Q LTYQLCHTYVRCTRSVSIPAPAYYAHLVAFRARYHLV+KE DS EGS  SG S+ R+P A+ +AV +H +TL+ MYFA
Sbjct:   15 FSVPRRPGYGTMGKPIKLLANCFQVDIPKMDVYLYDVDIKPEKCPRRVNREVVDSMVQHFKV-TIFGDRRPVYDGKKSLYTAQPLPVASAGVDLDVTLPGEGGKDRIFKVTIKFVSLVSWHMLHEVLTGRSTPDPLELDKPISTNPVHAVDVVLRHLPSMRYTPVGRSFFSSPEGYDHPLGGGREVWFGFHQSVRPAMWKMMLNIDVSATAFYKAQPVIQFMCEVLDIHNIDEQPRPLTDSHRVKFTKEIKGLKVEVTHCGTMRRKYRVCNVTRRPASHQTFPLQLENGQTVERTVAQYFREKYNLQLKYPHLPCLQVGQEQKHTYLPLEVCNIVAGQRCIKKLTDNQTSTMIKATARSAPDRQEEISRLVRSANYNSDPFVQEFQFRVRDEMAEVTGRVLPAPMLQYGGRVSSEHFMNRTVATPSHGVWDMRGKQFHTGVEIKMWAIACFATQRQCREEVLKGFTDQLRKISKDAGMPIQGQPCFCKYAQGADNVEPMFRHLKNTYAGLQLIIVILPGKTPVYAEVKRVGDTLLGMATQCVQVKNVVKTSPQTLSNLCLKINVKLGGINNILVPHQRPSVFQQPVIFLGADVTHPPAGDGKKPSIAAVVGSMDAHPSRYCATVRVQRPRQEVIQDLASMVRELLIQFYKSTHYKPTRIIFYRDGVSEGQFRQVLYYELLAIREACISLEKEYQPGITYIVVQKRHHTRLFCADRAERVGRSGNIPAGTTVDTDITHPYEFDFYLCSHAGIQGTSRPSHYYVLWDDNCFTADEFQLLTYQLCHTYVRCTRSVSIPAPAYYAHLVAFRARYHLVDKEHDSAEGSHVSGQSNGRDPQALAKAVQIHHDTLRTMYFA 867

[Close]

BLAST of AGO-2 vs. Ensembl Xenopus
Match: rbm26 (RNA binding motif protein 26 [Source:Xenbase;Acc:XB-GENE-960053])

HSP 1 Score: 1301.19 bits (3366), Expect = 0.000e+0
Identity = 616/838 (73.51%), Postives = 712/838 (84.96%), Query Frame = 1

Query:  277 FQPPSRPDQGTDGRTIQLKANHFEIVMPKGFLHHYDITITPEKCPRRVNRDIIQAMVNNMHYQKYFYNQKPVFDGRRNMYTREPLSIGKEKLELEVILPGEGKDRVFKVCLKHVSEVSLFALEEALQGRRQTIPAETVTALDVIMRHLPSMTYTPVGRSFFHNTGDYDNPLGGGREVWFGFHQSVRPSQWKMMLNIDVSATAFYKEQSVINFMFEVLEID--KDLKRPLTDSQRVKFTKEIKGLKVEINHCGPIKRKYRVCNVTRRSAQSQTFPLQSEQGQTIECTVTKYFQDRYGMKLQHPHLPCLQVGQEQKHTYLPLEVCNIVSGQRCIKKLTDMQTSTMIKATARSAPDREKEINNLVRRSNFNADPHLQIFGVSVNTRMADIQGRVIPAPKIQYGGRTKAQATPQQGVWDMRGKQFFSGIEIKVWAIACFAPQRTVREDSLRTFTQQLQKISNDAGMPIVGQPCFCKYATGQDQVEPMFRYLKNSFSGLQLIVVVLPGKTPVYAEVKRVGDIIFGLATQCVQAKNVNKPSPQTLSNLCLKINVKLGGINSILVPSVRPAVFKEPVIFLGADFTHPPAGDKTKPSIAAVVGSMDAHPSRYAATVSVQPHRQETIQDLAAMVKELLIQFYKSTRFKPTRIIYYRDGVSEGQFLNVLNHELKAIREACIKLEMSYQPGITFVVVQKRHHTRLFCSDKKDQMGRSGNIPAGTTVDQIITHPTEFDFYLCSHAGIQGTSRPSHYHVLWDDNRFSADEIQTLTYQLCHTYVRCTRSVSIPAPAYYAHLVAFRARYHLVEKELDSGEGSQKSGNSDERNPTAMMRAVTVHSETLKVMYFA 2784
            F+PP RPD GT GRTI+L+AN FE+ +PK  ++HY+I I PEKCPRRVNR+I++ MV +   Q  F ++KPVFDGR+N+YT  PL I ++K+ELEV LPGEGKDR+FKV +K ++ VSL AL +AL GR  ++P ET+ ALDV+MRHLPSM YTPVGRSFF  +    NPLGGGREVWFGFHQSVRPS WKMMLNIDVSATAFYK Q VI FM EVL+    ++ ++PLTDSQRVKFTKEIKGLKVEI HCG +KRKYRVCNVTRR A  QTFPLQ E GQT+ECTV +YF+DR+ + L++PHLPCLQVGQEQKHTYLPLEVCNIV+GQRCIKKLTD QTSTMI+ATARSAPDR++EI+ L+R ++FN DP ++ FG+ V   M D+ GRV+  P I YGGR KA ATP QGVWDMR KQF +GIEIKVWAIACFAPQR   E  L+TFT+QL+KIS DAGMPI GQPCFCKYA G D VEPMFR+LKN+++GLQL+VV+LPGKTPVYAEVKRVGD + G+ATQCVQ KNV + +PQTLSNLCLKINVKLGG+N+IL+P  RP VF++PVIFLGAD THPPAGD  KPSIAAVVGSMDAHP+RY ATV VQ HRQE IQDL+AMV+ELLIQFYKSTRFKPTRII+YRDGVSEGQF  VL+HEL AIREACIKLE  YQPGITF+VVQKRHHTRLFC+D+ +++G+SGNIPAGTTVD  ITHP+EFDFYLCSHAGIQGTSRPSHYHVLWDDNRFS+DE+Q LTYQLCHTYVRCTRSVSIPAPAYYAHLVAFRARYHLV+KE DS EGS  SG S+ R+  A+ +AV VH +TL+ MYFA
Sbjct:   58 FKPPPRPDFGTSGRTIKLQANFFEMDIPKIEIYHYEIDIKPEKCPRRVNREIVEHMVQHFKAQ-IFGDRKPVFDGRKNLYTAMPLPIARDKVELEVTLPGEGKDRIFKVAIKWMACVSLQALHDALSGRLPSVPFETIQALDVVMRHLPSMRYTPVGRSFFTASEGCANPLGGGREVWFGFHQSVRPSLWKMMLNIDVSATAFYKAQPVIEFMCEVLDFKSIEEQQKPLTDSQRVKFTKEIKGLKVEITHCGQMKRKYRVCNVTRRPASHQTFPLQQESGQTVECTVAQYFKDRHKLVLRYPHLPCLQVGQEQKHTYLPLEVCNIVAGQRCIKKLTDNQTSTMIRATARSAPDRQEEISKLMRSASFNTDPFVREFGIMVKDDMTDVTGRVLQPPSILYGGRNKAIATPVQGVWDMRNKQFHTGIEIKVWAIACFAPQRQCTEVHLKTFTEQLRKISRDAGMPIQGQPCFCKYAQGADSVEPMFRHLKNTYTGLQLVVVILPGKTPVYAEVKRVGDTVLGMATQCVQMKNVQRTTPQTLSNLCLKINVKLGGVNNILLPQGRPPVFQQPVIFLGADVTHPPAGDGKKPSIAAVVGSMDAHPNRYCATVRVQQHRQEIIQDLSAMVRELLIQFYKSTRFKPTRIIFYRDGVSEGQFQQVLHHELLAIREACIKLEKDYQPGITFIVVQKRHHTRLFCTDRNERVGKSGNIPAGTTVDTKITHPSEFDFYLCSHAGIQGTSRPSHYHVLWDDNRFSSDELQILTYQLCHTYVRCTRSVSIPAPAYYAHLVAFRARYHLVDKEHDSAEGSHTSGQSNGRDQQALAKAVQVHQDTLRTMYFA 894

[Close]

BLAST of AGO-2 vs. Ensembl Xenopus
Match: rbm26 (RNA binding motif protein 26 [Source:Xenbase;Acc:XB-GENE-960053])

HSP 1 Score: 1300.03 bits (3363), Expect = 0.000e+0
Identity = 615/838 (73.39%), Postives = 710/838 (84.73%), Query Frame = 1

Query:  277 FQPPSRPDQGTDGRTIQLKANHFEIVMPKGFLHHYDITITPEKCPRRVNRDIIQAMVNNMHYQKYFYNQKPVFDGRRNMYTREPLSIGKEKLELEVILPGEGKDRVFKVCLKHVSEVSLFALEEALQGRRQTIPAETVTALDVIMRHLPSMTYTPVGRSFFHNTGDYDNPLGGGREVWFGFHQSVRPSQWKMMLNIDVSATAFYKEQSVINFMFEVLEID--KDLKRPLTDSQRVKFTKEIKGLKVEINHCGPIKRKYRVCNVTRRSAQSQTFPLQSEQGQTIECTVTKYFQDRYGMKLQHPHLPCLQVGQEQKHTYLPLEVCNIVSGQRCIKKLTDMQTSTMIKATARSAPDREKEINNLVRRSNFNADPHLQIFGVSVNTRMADIQGRVIPAPKIQYGGRTKAQATPQQGVWDMRGKQFFSGIEIKVWAIACFAPQRTVREDSLRTFTQQLQKISNDAGMPIVGQPCFCKYATGQDQVEPMFRYLKNSFSGLQLIVVVLPGKTPVYAEVKRVGDIIFGLATQCVQAKNVNKPSPQTLSNLCLKINVKLGGINSILVPSVRPAVFKEPVIFLGADFTHPPAGDKTKPSIAAVVGSMDAHPSRYAATVSVQPHRQETIQDLAAMVKELLIQFYKSTRFKPTRIIYYRDGVSEGQFLNVLNHELKAIREACIKLEMSYQPGITFVVVQKRHHTRLFCSDKKDQMGRSGNIPAGTTVDQIITHPTEFDFYLCSHAGIQGTSRPSHYHVLWDDNRFSADEIQTLTYQLCHTYVRCTRSVSIPAPAYYAHLVAFRARYHLVEKELDSGEGSQKSGNSDERNPTAMMRAVTVHSETLKVMYFA 2784
              PP RPD GT GRTI+L+AN FE+ +PK  ++HY+I I PEKCPRRVNR+I++ MV +   Q  F ++KPVFDGR+N+YT  PL I ++K+ELEV LPGEGKDR+FKV +K ++ VSL AL +AL GR  ++P ET+ ALDV+MRHLPSM YTPVGRSFF  +    NPLGGGREVWFGFHQSVRPS WKMMLNIDVSATAFYK Q VI FM EVL+    ++ ++PLTDSQRVKFTKEIKGLKVEI HCG +KRKYRVCNVTRR A  QTFPLQ E GQT+ECTV +YF+DR+ + L++PHLPCLQVGQEQKHTYLPLEVCNIV+GQRCIKKLTD QTSTMI+ATARSAPDR++EI+ L+R ++FN DP ++ FG+ V   M D+ GRV+  P I YGGR KA ATP QGVWDMR KQF +GIEIKVWAIACFAPQR   E  L+TFT+QL+KIS DAGMPI GQPCFCKYA G D VEPMFR+LKN+++GLQL+VV+LPGKTPVYAEVKRVGD + G+ATQCVQ KNV + +PQTLSNLCLKINVKLGG+N+IL+P  RP VF++PVIFLGAD THPPAGD  KPSIAAVVGSMDAHP+RY ATV VQ HRQE IQDL+AMV+ELLIQFYKSTRFKPTRII+YRDGVSEGQF  VL+HEL AIREACIKLE  YQPGITF+VVQKRHHTRLFC+D+ +++G+SGNIPAGTTVD  ITHP+EFDFYLCSHAGIQGTSRPSHYHVLWDDNRFS+DE+Q LTYQLCHTYVRCTRSVSIPAPAYYAHLVAFRARYHLV+KE DS EGS  SG S+ R+  A+ +AV VH +TL+ MYFA
Sbjct:    6 IHPPPRPDFGTSGRTIKLQANFFEMDIPKIEIYHYEIDIKPEKCPRRVNREIVEHMVQHFKAQ-IFGDRKPVFDGRKNLYTAMPLPIARDKVELEVTLPGEGKDRIFKVAIKWMACVSLQALHDALSGRLPSVPFETIQALDVVMRHLPSMRYTPVGRSFFTASEGCANPLGGGREVWFGFHQSVRPSLWKMMLNIDVSATAFYKAQPVIEFMCEVLDFKSIEEQQKPLTDSQRVKFTKEIKGLKVEITHCGQMKRKYRVCNVTRRPASHQTFPLQQESGQTVECTVAQYFKDRHKLVLRYPHLPCLQVGQEQKHTYLPLEVCNIVAGQRCIKKLTDNQTSTMIRATARSAPDRQEEISKLMRSASFNTDPFVREFGIMVKDDMTDVTGRVLQPPSILYGGRNKAIATPVQGVWDMRNKQFHTGIEIKVWAIACFAPQRQCTEVHLKTFTEQLRKISRDAGMPIQGQPCFCKYAQGADSVEPMFRHLKNTYTGLQLVVVILPGKTPVYAEVKRVGDTVLGMATQCVQMKNVQRTTPQTLSNLCLKINVKLGGVNNILLPQGRPPVFQQPVIFLGADVTHPPAGDGKKPSIAAVVGSMDAHPNRYCATVRVQQHRQEIIQDLSAMVRELLIQFYKSTRFKPTRIIFYRDGVSEGQFQQVLHHELLAIREACIKLEKDYQPGITFIVVQKRHHTRLFCTDRNERVGKSGNIPAGTTVDTKITHPSEFDFYLCSHAGIQGTSRPSHYHVLWDDNRFSSDELQILTYQLCHTYVRCTRSVSIPAPAYYAHLVAFRARYHLVDKEHDSAEGSHTSGQSNGRDQQALAKAVQVHQDTLRTMYFA 842

[Close]

BLAST of AGO-2 vs. Ensembl Xenopus
Match: rbm26 (RNA binding motif protein 26 [Source:Xenbase;Acc:XB-GENE-960053])

HSP 1 Score: 1292.72 bits (3344), Expect = 0.000e+0
Identity = 615/842 (73.04%), Postives = 710/842 (84.32%), Query Frame = 1

Query:  283 PPSRPDQGTDGRTIQLKANHFEIVMPKGFLHHYDITITPEKCPRRVNRDIIQAMVNNMHYQKYFYNQKPVFDGRRNMYTREPLSIGKEKLELEVILPGEGKDRVFKVCLKHVSEVSLFALEEALQGRRQTIPAETVTALDVIMRHLPSMTYTPVGRSFFHNTGDYDNPLGGGREVWFGFHQSVRPSQWKMMLNIDVSATAFYKEQSVINFMFEVLEID--KDLKRPLTDSQRVKFTKEIKGLKVEINHCGPIKRKYRVCNVTRRSAQSQTFPLQSEQGQTIECTVTKYFQDRYGMKLQHPHLPCLQVGQEQKHTYLPLEVCNIVSGQRCIKKLTDMQTSTMIKATARSAPDREKEINNLVRRSNFNADPHLQIFGVSVNTRMADIQGRVIPAPKIQYGGRT------KAQATPQQGVWDMRGKQFFSGIEIKVWAIACFAPQRTVREDSLRTFTQQLQKISNDAGMPIVGQPCFCKYATGQDQVEPMFRYLKNSFSGLQLIVVVLPGKTPVYAEVKRVGDIIFGLATQCVQAKNVNKPSPQTLSNLCLKINVKLGGINSILVPSVRPAVFKEPVIFLGADFTHPPAGDKTKPSIAAVVGSMDAHPSRYAATVSVQPHRQETIQDLAAMVKELLIQFYKSTRFKPTRIIYYRDGVSEGQFLNVLNHELKAIREACIKLEMSYQPGITFVVVQKRHHTRLFCSDKKDQMGRSGNIPAGTTVDQIITHPTEFDFYLCSHAGIQGTSRPSHYHVLWDDNRFSADEIQTLTYQLCHTYVRCTRSVSIPAPAYYAHLVAFRARYHLVEKELDSGEGSQKSGNSDERNPTAMMRAVTVHSETLKVMYFA 2784
            PP RPD GT GRTI+L+AN FE+ +PK  ++HY+I I PEKCPRRVNR+I++ MV +   Q  F ++KPVFDGR+N+YT  PL I ++K+ELEV LPGEGKDR+FKV +K ++ VSL AL +AL GR  ++P ET+ ALDV+MRHLPSM YTPVGRSFF  +    NPLGGGREVWFGFHQSVRPS WKMMLNIDVSATAFYK Q VI FM EVL+    ++ ++PLTDSQRVKFTKEIKGLKVEI HCG +KRKYRVCNVTRR A  QTFPLQ E GQT+ECTV +YF+DR+ + L++PHLPCLQVGQEQKHTYLPLEVCNIV+GQRCIKKLTD QTSTMI+ATARSAPDR++EI+ L+R ++FN DP ++ FG+ V   M D+ GRV+  P I YGGR       KA ATP QGVWDMR KQF +GIEIKVWAIACFAPQR   E  L+TFT+QL+KIS DAGMPI GQPCFCKYA G D VEPMFR+LKN+++GLQL+VV+LPGKTPVYAEVKRVGD + G+ATQCVQ KNV + +PQTLSNLCLKINVKLGG+N+IL+P  RP VF++PVIFLGAD THPPAGD  KPSIAAVVGSMDAHP+RY ATV VQ HRQE IQDL+AMV+ELLIQFYKSTRFKPTRII+YRDGVSEGQF  VL+HEL AIREACIKLE  YQPGITF+VVQKRHHTRLFC+D+ +++G+SGNIPAGTTVD  ITHP+EFDFYLCSHAGIQGTSRPSHYHVLWDDNRFS+DE+Q LTYQLCHTYVRCTRSVSIPAPAYYAHLVAFRARYHLV+KE DS EGS  SG S+ R+  A+ +AV VH +TL+ MYFA
Sbjct:   18 PPPRPDFGTSGRTIKLQANFFEMDIPKIEIYHYEIDIKPEKCPRRVNREIVEHMVQHFKAQ-IFGDRKPVFDGRKNLYTAMPLPIARDKVELEVTLPGEGKDRIFKVAIKWMACVSLQALHDALSGRLPSVPFETIQALDVVMRHLPSMRYTPVGRSFFTASEGCANPLGGGREVWFGFHQSVRPSLWKMMLNIDVSATAFYKAQPVIEFMCEVLDFKSIEEQQKPLTDSQRVKFTKEIKGLKVEITHCGQMKRKYRVCNVTRRPASHQTFPLQQESGQTVECTVAQYFKDRHKLVLRYPHLPCLQVGQEQKHTYLPLEVCNIVAGQRCIKKLTDNQTSTMIRATARSAPDRQEEISKLMRSASFNTDPFVREFGIMVKDDMTDVTGRVLQPPSILYGGRVWEEPNNKAIATPVQGVWDMRNKQFHTGIEIKVWAIACFAPQRQCTEVHLKTFTEQLRKISRDAGMPIQGQPCFCKYAQGADSVEPMFRHLKNTYTGLQLVVVILPGKTPVYAEVKRVGDTVLGMATQCVQMKNVQRTTPQTLSNLCLKINVKLGGVNNILLPQGRPPVFQQPVIFLGADVTHPPAGDGKKPSIAAVVGSMDAHPNRYCATVRVQQHRQEIIQDLSAMVRELLIQFYKSTRFKPTRIIFYRDGVSEGQFQQVLHHELLAIREACIKLEKDYQPGITFIVVQKRHHTRLFCTDRNERVGKSGNIPAGTTVDTKITHPSEFDFYLCSHAGIQGTSRPSHYHVLWDDNRFSSDELQILTYQLCHTYVRCTRSVSIPAPAYYAHLVAFRARYHLVDKEHDSAEGSHTSGQSNGRDQQALAKAVQVHQDTLRTMYFA 858

[Close]

BLAST of AGO-2 vs. Ensembl Xenopus
Match: rbm26 (RNA binding motif protein 26 [Source:Xenbase;Acc:XB-GENE-960053])

HSP 1 Score: 1290.79 bits (3339), Expect = 0.000e+0
Identity = 610/829 (73.58%), Postives = 705/829 (85.04%), Query Frame = 1

Query:  304 GTDGRTIQLKANHFEIVMPKGFLHHYDITITPEKCPRRVNRDIIQAMVNNMHYQKYFYNQKPVFDGRRNMYTREPLSIGKEKLELEVILPGEGKDRVFKVCLKHVSEVSLFALEEALQGRRQTIPAETVTALDVIMRHLPSMTYTPVGRSFFHNTGDYDNPLGGGREVWFGFHQSVRPSQWKMMLNIDVSATAFYKEQSVINFMFEVLEID--KDLKRPLTDSQRVKFTKEIKGLKVEINHCGPIKRKYRVCNVTRRSAQSQTFPLQSEQGQTIECTVTKYFQDRYGMKLQHPHLPCLQVGQEQKHTYLPLEVCNIVSGQRCIKKLTDMQTSTMIKATARSAPDREKEINNLVRRSNFNADPHLQIFGVSVNTRMADIQGRVIPAPKIQYGGRTKAQATPQQGVWDMRGKQFFSGIEIKVWAIACFAPQRTVREDSLRTFTQQLQKISNDAGMPIVGQPCFCKYATGQDQVEPMFRYLKNSFSGLQLIVVVLPGKTPVYAEVKRVGDIIFGLATQCVQAKNVNKPSPQTLSNLCLKINVKLGGINSILVPSVRPAVFKEPVIFLGADFTHPPAGDKTKPSIAAVVGSMDAHPSRYAATVSVQPHRQETIQDLAAMVKELLIQFYKSTRFKPTRIIYYRDGVSEGQFLNVLNHELKAIREACIKLEMSYQPGITFVVVQKRHHTRLFCSDKKDQMGRSGNIPAGTTVDQIITHPTEFDFYLCSHAGIQGTSRPSHYHVLWDDNRFSADEIQTLTYQLCHTYVRCTRSVSIPAPAYYAHLVAFRARYHLVEKELDSGEGSQKSGNSDERNPTAMMRAVTVHSETLKVMYFA 2784
            GT GRTI+L+AN FE+ +PK  ++HY+I I PEKCPRRVNR+I++ MV +   Q  F ++KPVFDGR+N+YT  PL I ++K+ELEV LPGEGKDR+FKV +K ++ VSL AL +AL GR  ++P ET+ ALDV+MRHLPSM YTPVGRSFF  +    NPLGGGREVWFGFHQSVRPS WKMMLNIDVSATAFYK Q VI FM EVL+    ++ ++PLTDSQRVKFTKEIKGLKVEI HCG +KRKYRVCNVTRR A  QTFPLQ E GQT+ECTV +YF+DR+ + L++PHLPCLQVGQEQKHTYLPLEVCNIV+GQRCIKKLTD QTSTMI+ATARSAPDR++EI+ L+R ++FN DP ++ FG+ V   M D+ GRV+  P I YGGR KA ATP QGVWDMR KQF +GIEIKVWAIACFAPQR   E  L+TFT+QL+KIS DAGMPI GQPCFCKYA G D VEPMFR+LKN+++GLQL+VV+LPGKTPVYAEVKRVGD + G+ATQCVQ KNV + +PQTLSNLCLKINVKLGG+N+IL+P  RP VF++PVIFLGAD THPPAGD  KPSIAAVVGSMDAHP+RY ATV VQ HRQE IQDL+AMV+ELLIQFYKSTRFKPTRII+YRDGVSEGQF  VL+HEL AIREACIKLE  YQPGITF+VVQKRHHTRLFC+D+ +++G+SGNIPAGTTVD  ITHP+EFDFYLCSHAGIQGTSRPSHYHVLWDDNRFS+DE+Q LTYQLCHTYVRCTRSVSIPAPAYYAHLVAFRARYHLV+KE DS EGS  SG S+ R+  A+ +AV VH +TL+ MYFA
Sbjct:    5 GTSGRTIKLQANFFEMDIPKIEIYHYEIDIKPEKCPRRVNREIVEHMVQHFKAQ-IFGDRKPVFDGRKNLYTAMPLPIARDKVELEVTLPGEGKDRIFKVAIKWMACVSLQALHDALSGRLPSVPFETIQALDVVMRHLPSMRYTPVGRSFFTASEGCANPLGGGREVWFGFHQSVRPSLWKMMLNIDVSATAFYKAQPVIEFMCEVLDFKSIEEQQKPLTDSQRVKFTKEIKGLKVEITHCGQMKRKYRVCNVTRRPASHQTFPLQQESGQTVECTVAQYFKDRHKLVLRYPHLPCLQVGQEQKHTYLPLEVCNIVAGQRCIKKLTDNQTSTMIRATARSAPDRQEEISKLMRSASFNTDPFVREFGIMVKDDMTDVTGRVLQPPSILYGGRNKAIATPVQGVWDMRNKQFHTGIEIKVWAIACFAPQRQCTEVHLKTFTEQLRKISRDAGMPIQGQPCFCKYAQGADSVEPMFRHLKNTYTGLQLVVVILPGKTPVYAEVKRVGDTVLGMATQCVQMKNVQRTTPQTLSNLCLKINVKLGGVNNILLPQGRPPVFQQPVIFLGADVTHPPAGDGKKPSIAAVVGSMDAHPNRYCATVRVQQHRQEIIQDLSAMVRELLIQFYKSTRFKPTRIIFYRDGVSEGQFQQVLHHELLAIREACIKLEKDYQPGITFIVVQKRHHTRLFCTDRNERVGKSGNIPAGTTVDTKITHPSEFDFYLCSHAGIQGTSRPSHYHVLWDDNRFSSDELQILTYQLCHTYVRCTRSVSIPAPAYYAHLVAFRARYHLVDKEHDSAEGSHTSGQSNGRDQQALAKAVQVHQDTLRTMYFA 832

[Close]

BLAST of AGO-2 vs. Ensembl Xenopus
Match: rbm26 (RNA binding motif protein 26 [Source:Xenbase;Acc:XB-GENE-960053])

HSP 1 Score: 1290.4 bits (3338), Expect = 0.000e+0
Identity = 616/848 (72.64%), Postives = 712/848 (83.96%), Query Frame = 1

Query:  277 FQPPSRPDQGTDGRTIQLKANHFEIVMPKGFLHHYDITITPEKCPRRVNRDIIQAMVNNMHYQKYFYNQKPVFDGRRNMYTREPLSIGKEK-LELEVILPGEGKDRVFKVCLKHVSEVSLFALEEALQGRRQTIPAETVTALDVIMRHLPSMTYTPVGRSFFHNTGDYDNPLGGGREVWFGFHQSVRPSQWKMMLNIDVSATAFYKEQSVINFMFEVLEID--KDLKRPLTDSQRVKFTKEIKGLKVEINHCGPIKRKYRVCNVTRRSAQSQTFPLQSEQGQTIECTVTKYFQDRYGMKLQHPHLPCLQVGQEQKHTYLPLEVCNIVSGQRCIKKLTDMQTSTMIKATARSAPDREKEINNLVRRSNFNADPHLQIFGVSVNTRMADIQGRVIPAPKIQYGGRT---------KAQATPQQGVWDMRGKQFFSGIEIKVWAIACFAPQRTVREDSLRTFTQQLQKISNDAGMPIVGQPCFCKYATGQDQVEPMFRYLKNSFSGLQLIVVVLPGKTPVYAEVKRVGDIIFGLATQCVQAKNVNKPSPQTLSNLCLKINVKLGGINSILVPSVRPAVFKEPVIFLGADFTHPPAGDKTKPSIAAVVGSMDAHPSRYAATVSVQPHRQETIQDLAAMVKELLIQFYKSTRFKPTRIIYYRDGVSEGQFLNVLNHELKAIREACIKLEMSYQPGITFVVVQKRHHTRLFCSDKKDQMGRSGNIPAGTTVDQIITHPTEFDFYLCSHAGIQGTSRPSHYHVLWDDNRFSADEIQTLTYQLCHTYVRCTRSVSIPAPAYYAHLVAFRARYHLVEKELDSGEGSQKSGNSDERNPTAMMRAVTVHSETLKVMYFA 2784
            F+PP RPD GT GRTI+L+AN FE+ +PK  ++HY+I I PEKCPRRVNR+I++ MV +   Q  F ++KPVFDGR+N+YT  PL I ++K +ELEV LPGEGKDR+FKV +K ++ VSL AL +AL GR  ++P ET+ ALDV+MRHLPSM YTPVGRSFF  +    NPLGGGREVWFGFHQSVRPS WKMMLNIDVSATAFYK Q VI FM EVL+    ++ ++PLTDSQRVKFTKEIKGLKVEI HCG +KRKYRVCNVTRR A  QTFPLQ E GQT+ECTV +YF+DR+ + L++PHLPCLQVGQEQKHTYLPLEVCNIV+GQRCIKKLTD QTSTMI+ATARSAPDR++EI+ L+R ++FN DP ++ FG+ V   M D+ GRV+  P I YGGR          KA ATP QGVWDMR KQF +GIEIKVWAIACFAPQR   E  L+TFT+QL+KIS DAGMPI GQPCFCKYA G D VEPMFR+LKN+++GLQL+VV+LPGKTPVYAEVKRVGD + G+ATQCVQ KNV + +PQTLSNLCLKINVKLGG+N+IL+P  RP VF++PVIFLGAD THPPAGD  KPSIAAVVGSMDAHP+RY ATV VQ HRQE IQDL+AMV+ELLIQFYKSTRFKPTRII+YRDGVSEGQF  VL+HEL AIREACIKLE  YQPGITF+VVQKRHHTRLFC+D+ +++G+SGNIPAGTTVD  ITHP+EFDFYLCSHAGIQGTSRPSHYHVLWDDNRFS+DE+Q LTYQLCHTYVRCTRSVSIPAPAYYAHLVAFRARYHLV+KE DS EGS  SG S+ R+  A+ +AV VH +TL+ MYFA
Sbjct:   25 FKPPPRPDFGTSGRTIKLQANFFEMDIPKIEIYHYEIDIKPEKCPRRVNREIVEHMVQHFKAQ-IFGDRKPVFDGRKNLYTAMPLPIARDKQVELEVTLPGEGKDRIFKVAIKWMACVSLQALHDALSGRLPSVPFETIQALDVVMRHLPSMRYTPVGRSFFTASEGCANPLGGGREVWFGFHQSVRPSLWKMMLNIDVSATAFYKAQPVIEFMCEVLDFKSIEEQQKPLTDSQRVKFTKEIKGLKVEITHCGQMKRKYRVCNVTRRPASHQTFPLQQESGQTVECTVAQYFKDRHKLVLRYPHLPCLQVGQEQKHTYLPLEVCNIVAGQRCIKKLTDNQTSTMIRATARSAPDRQEEISKLMRSASFNTDPFVREFGIMVKDDMTDVTGRVLQPPSILYGGRVWEEPNAPLNKAIATPVQGVWDMRNKQFHTGIEIKVWAIACFAPQRQCTEVHLKTFTEQLRKISRDAGMPIQGQPCFCKYAQGADSVEPMFRHLKNTYTGLQLVVVILPGKTPVYAEVKRVGDTVLGMATQCVQMKNVQRTTPQTLSNLCLKINVKLGGVNNILLPQGRPPVFQQPVIFLGADVTHPPAGDGKKPSIAAVVGSMDAHPNRYCATVRVQQHRQEIIQDLSAMVRELLIQFYKSTRFKPTRIIFYRDGVSEGQFQQVLHHELLAIREACIKLEKDYQPGITFIVVQKRHHTRLFCTDRNERVGKSGNIPAGTTVDTKITHPSEFDFYLCSHAGIQGTSRPSHYHVLWDDNRFSSDELQILTYQLCHTYVRCTRSVSIPAPAYYAHLVAFRARYHLVDKEHDSAEGSHTSGQSNGRDQQALAKAVQVHQDTLRTMYFA 871

[Close]

BLAST of AGO-2 vs. Ensembl Mouse
Match: Ago2 (argonaute RISC catalytic subunit 2 [Source:MGI Symbol;Acc:MGI:2446632])

HSP 1 Score: 1306.97 bits (3381), Expect = 0.000e+0
Identity = 619/838 (73.87%), Postives = 714/838 (85.20%), Query Frame = 1

Query:  277 FQPPSRPDQGTDGRTIQLKANHFEIVMPKGFLHHYDITITPEKCPRRVNRDIIQAMVNNMHYQKYFYNQKPVFDGRRNMYTREPLSIGKEKLELEVILPGEGKDRVFKVCLKHVSEVSLFALEEALQGRRQTIPAETVTALDVIMRHLPSMTYTPVGRSFFHNTGDYDNPLGGGREVWFGFHQSVRPSQWKMMLNIDVSATAFYKEQSVINFMFEVLEID--KDLKRPLTDSQRVKFTKEIKGLKVEINHCGPIKRKYRVCNVTRRSAQSQTFPLQSEQGQTIECTVTKYFQDRYGMKLQHPHLPCLQVGQEQKHTYLPLEVCNIVSGQRCIKKLTDMQTSTMIKATARSAPDREKEINNLVRRSNFNADPHLQIFGVSVNTRMADIQGRVIPAPKIQYGGRTKAQATPQQGVWDMRGKQFFSGIEIKVWAIACFAPQRTVREDSLRTFTQQLQKISNDAGMPIVGQPCFCKYATGQDQVEPMFRYLKNSFSGLQLIVVVLPGKTPVYAEVKRVGDIIFGLATQCVQAKNVNKPSPQTLSNLCLKINVKLGGINSILVPSVRPAVFKEPVIFLGADFTHPPAGDKTKPSIAAVVGSMDAHPSRYAATVSVQPHRQETIQDLAAMVKELLIQFYKSTRFKPTRIIYYRDGVSEGQFLNVLNHELKAIREACIKLEMSYQPGITFVVVQKRHHTRLFCSDKKDQMGRSGNIPAGTTVDQIITHPTEFDFYLCSHAGIQGTSRPSHYHVLWDDNRFSADEIQTLTYQLCHTYVRCTRSVSIPAPAYYAHLVAFRARYHLVEKELDSGEGSQKSGNSDERNPTAMMRAVTVHSETLKVMYFA 2784
            F+PP RPD GT GRTI+L+AN FE+ +PK  ++HY++ I PEKCPRRVNR+I++ MV +   Q  F ++KPVFDGR+N+YT  PL IG++K+ELEV LPGEGKDR+FKV +K VS VSL AL +AL GR  ++P ET+ ALDV+MRHLPSM YTPVGRSFF  +    NPLGGGREVWFGFHQSVRPS WKMMLNIDVSATAFYK Q VI F+ EVL+    ++ ++PLTDSQRVKFTKEIKGLKVEI HCG +KRKYRVCNVTRR A  QTFPLQ E GQT+ECTV +YF+DR+ + L++PHLPCLQVGQEQKHTYLPLEVCNIV+GQRCIKKLTD QTSTMI+ATARSAPDR++EI+ L+R ++FN DP+++ FG+ V   M D+ GRV+  P I YGGR KA ATP QGVWDMR KQF +GIEIKVWAIACFAPQR   E  L++FT+QL+KIS DAGMPI GQPCFCKYA G D VEPMFR+LKN+++GLQL+VV+LPGKTPVYAEVKRVGD + G+ATQCVQ KNV + +PQTLSNLCLKINVKLGG+N+IL+P  RP VF++PVIFLGAD THPPAGD  KPSIAAVVGSMDAHP+RY ATV VQ HRQE IQDLAAMV+ELLIQFYKSTRFKPTRII+YRDGVSEGQF  VL+HEL AIREACIKLE  YQPGITF+VVQKRHHTRLFC+DK +++G+SGNIPAGTTVD  ITHPTEFDFYLCSHAGIQGTSRPSHYHVLWDDNRFS+DE+Q LTYQLCHTYVRCTRSVSIPAPAYYAHLVAFRARYHLV+KE DS EGS  SG S+ R+  A+ +AV VH +TL+ MYFA
Sbjct:   24 FKPPPRPDFGTTGRTIKLQANFFEMDIPKIDIYHYELDIKPEKCPRRVNREIVEHMVQHFKTQ-IFGDRKPVFDGRKNLYTAMPLPIGRDKVELEVTLPGEGKDRIFKVSIKWVSCVSLQALHDALSGRLPSVPFETIQALDVVMRHLPSMRYTPVGRSFFTASEGCSNPLGGGREVWFGFHQSVRPSLWKMMLNIDVSATAFYKAQPVIEFVCEVLDFKSIEEQQKPLTDSQRVKFTKEIKGLKVEITHCGQMKRKYRVCNVTRRPASHQTFPLQQESGQTVECTVAQYFKDRHKLVLRYPHLPCLQVGQEQKHTYLPLEVCNIVAGQRCIKKLTDNQTSTMIRATARSAPDRQEEISKLMRSASFNTDPYVREFGIMVKDEMTDVTGRVLQPPSILYGGRNKAIATPVQGVWDMRNKQFHTGIEIKVWAIACFAPQRQCTEVHLKSFTEQLRKISRDAGMPIQGQPCFCKYAQGADSVEPMFRHLKNTYAGLQLVVVILPGKTPVYAEVKRVGDTVLGMATQCVQMKNVQRTTPQTLSNLCLKINVKLGGVNNILLPQGRPPVFQQPVIFLGADVTHPPAGDGKKPSIAAVVGSMDAHPNRYCATVRVQQHRQEIIQDLAAMVRELLIQFYKSTRFKPTRIIFYRDGVSEGQFQQVLHHELLAIREACIKLEKDYQPGITFIVVQKRHHTRLFCTDKNERVGKSGNIPAGTTVDTKITHPTEFDFYLCSHAGIQGTSRPSHYHVLWDDNRFSSDELQILTYQLCHTYVRCTRSVSIPAPAYYAHLVAFRARYHLVDKEHDSAEGSHTSGQSNGRDHQALAKAVQVHQDTLRTMYFA 860

[Close]

BLAST of AGO-2 vs. Ensembl Mouse
Match: Ago1 (argonaute RISC catalytic subunit 1 [Source:MGI Symbol;Acc:MGI:2446630])

HSP 1 Score: 1256.89 bits (3251), Expect = 0.000e+0
Identity = 595/838 (71.00%), Postives = 701/838 (83.65%), Query Frame = 1

Query:  277 FQPPSRPDQGTDGRTIQLKANHFEIVMPKGFLHHYDITITPEKCPRRVNRDIIQAMVNNMHYQKYFYNQKPVFDGRRNMYTREPLSIGKEKLELEVILPGEGKDRVFKVCLKHVSEVSLFALEEALQGRRQTIPAETVTALDVIMRHLPSMTYTPVGRSFFHNTGDYDNPLGGGREVWFGFHQSVRPSQWKMMLNIDVSATAFYKEQSVINFMFEVLEIDK--DLKRPLTDSQRVKFTKEIKGLKVEINHCGPIKRKYRVCNVTRRSAQSQTFPLQSEQGQTIECTVTKYFQDRYGMKLQHPHLPCLQVGQEQKHTYLPLEVCNIVSGQRCIKKLTDMQTSTMIKATARSAPDREKEINNLVRRSNFNADPHLQIFGVSVNTRMADIQGRVIPAPKIQYGGRTKAQATPQQGVWDMRGKQFFSGIEIKVWAIACFAPQRTVREDSLRTFTQQLQKISNDAGMPIVGQPCFCKYATGQDQVEPMFRYLKNSFSGLQLIVVVLPGKTPVYAEVKRVGDIIFGLATQCVQAKNVNKPSPQTLSNLCLKINVKLGGINSILVPSVRPAVFKEPVIFLGADFTHPPAGDKTKPSIAAVVGSMDAHPSRYAATVSVQPHRQETIQDLAAMVKELLIQFYKSTRFKPTRIIYYRDGVSEGQFLNVLNHELKAIREACIKLEMSYQPGITFVVVQKRHHTRLFCSDKKDQMGRSGNIPAGTTVDQIITHPTEFDFYLCSHAGIQGTSRPSHYHVLWDDNRFSADEIQTLTYQLCHTYVRCTRSVSIPAPAYYAHLVAFRARYHLVEKELDSGEGSQKSGNSDERNPTAMMRAVTVHSETLKVMYFA 2784
            FQ P RP  GT G+ I+L AN+FE+ +PK  ++HY++ I P+KCPRRVNR++++ MV +   Q  F ++KPV+DG++N+YT   L IG E+++ EV +PGEGKDR+FKV +K ++ VS   L EAL   +  +P E+V ALDV MRHL SM YTPVGRSFF     Y +PLGGGREVWFGFHQSVRP+ WKMMLNIDVSATAFYK Q VI FM EVL+I    +  +PLTDSQRV+FTKEIKGLKVE+ HCG +KRKYRVCNVTRR A  QTFPLQ E GQT+ECTV +YF+ +Y ++L++PHLPCLQVGQEQKHTYLPLEVCNIV+GQRCIKKLTD QTSTMIKATARSAPDR++EI+ L++ +++N DP++Q FG+ V   M ++ GRV+PAP +QYGGR +A ATP QGVWDMRGKQF++GIEIKVWAIACFAPQ+  RE+ L+ FT QL+KIS DAGMPI GQPCFCKYA G D VEPMFR+LKN++SGLQLI+V+LPGKTPVYAEVKRVGD + G+ATQCVQ KNV K SPQTLSNLCLKINVKLGGIN+ILVP  R AVF++PVIFLGAD THPPAGD  KPSI AVVGSMDAHPSRY ATV VQ  RQE I+DL+ MV+ELLIQFYKSTRFKPTRII+YRDGV EGQ   +L++EL AIR+ACIKLE  YQPGIT++VVQKRHHTRLFC+DK +++G+SGNIPAGTTVD  ITHP EFDFYLCSHAGIQGTSRPSHY+VLWDDNRF+ADE+Q LTYQLCHTYVRCTRSVSIPAPAYYA LVAFRARYHLV+KE DSGEGS  SG S+ R+P A+ +AV VH +TL+ MYFA
Sbjct:   21 FQAPRRPGIGTVGKPIKLLANYFEVDIPKIDVYHYEVDIKPDKCPRRVNREVVEYMVQHFKPQ-IFGDRKPVYDGKKNIYTVTALPIGNERVDFEVTIPGEGKDRIFKVSIKWLAIVSWRMLHEALVSGQIPVPLESVQALDVAMRHLASMRYTPVGRSFFSPPEGYYHPLGGGREVWFGFHQSVRPAMWKMMLNIDVSATAFYKAQPVIEFMCEVLDIRNIDEQPKPLTDSQRVRFTKEIKGLKVEVTHCGQMKRKYRVCNVTRRPASHQTFPLQLESGQTVECTVAQYFKQKYNLQLKYPHLPCLQVGQEQKHTYLPLEVCNIVAGQRCIKKLTDNQTSTMIKATARSAPDRQEEISRLMKNASYNLDPYIQEFGIKVKDDMTEVTGRVLPAPILQYGGRNRAIATPNQGVWDMRGKQFYNGIEIKVWAIACFAPQKQCREEVLKNFTDQLRKISKDAGMPIQGQPCFCKYAQGADSVEPMFRHLKNTYSGLQLIIVILPGKTPVYAEVKRVGDTLLGMATQCVQVKNVVKTSPQTLSNLCLKINVKLGGINNILVPHQRSAVFQQPVIFLGADVTHPPAGDGKKPSITAVVGSMDAHPSRYCATVRVQRPRQEIIEDLSYMVRELLIQFYKSTRFKPTRIIFYRDGVPEGQLPQILHYELLAIRDACIKLEKDYQPGITYIVVQKRHHTRLFCADKNERIGKSGNIPAGTTVDTNITHPFEFDFYLCSHAGIQGTSRPSHYYVLWDDNRFTADELQILTYQLCHTYVRCTRSVSIPAPAYYARLVAFRARYHLVDKEHDSGEGSHISGQSNGRDPQALAKAVQVHQDTLRTMYFA 857

[Close]

BLAST of AGO-2 vs. Ensembl Mouse
Match: Ago3 (argonaute RISC catalytic subunit 3 [Source:MGI Symbol;Acc:MGI:2446634])

HSP 1 Score: 1232.24 bits (3187), Expect = 0.000e+0
Identity = 594/847 (70.13%), Postives = 689/847 (81.35%), Query Frame = 1

Query:  277 FQPPSRPDQGTDGRTIQLKANHFEIVMPKGFLHHYDITITPEKCPRRVNRDIIQAMVNNMHYQKYFYNQKPVFDGRRNMYTREPLSIGKEKLELEVILPGEG-KDRVFKVCLKHVSEVSLFALEEALQGRRQTIPAET--------VTALDVIMRHLPSMTYTPVGRSFFHNTGDYDNPLGGGREVWFGFHQSVRPSQWKMMLNIDVSATAFYKEQSVINFMFEVLEIDK--DLKRPLTDSQRVKFTKEIKGLKVEINHCGPIKRKYRVCNVTRRSAQSQTFPLQSEQGQTIECTVTKYFQDRYGMKLQHPHLPCLQVGQEQKHTYLPLEVCNIVSGQRCIKKLTDMQTSTMIKATARSAPDREKEINNLVRRSNFNADPHLQIFGVSVNTRMADIQGRVIPAPKIQYGGRTKAQATPQQGVWDMRGKQFFSGIEIKVWAIACFAPQRTVREDSLRTFTQQLQKISNDAGMPIVGQPCFCKYATGQDQVEPMFRYLKNSFSGLQLIVVVLPGKTPVYAEVKRVGDIIFGLATQCVQAKNVNKPSPQTLSNLCLKINVKLGGINSILVPSVRPAVFKEPVIFLGADFTHPPAGDKTKPSIAAVVGSMDAHPSRYAATVSVQPHRQETIQDLAAMVKELLIQFYKSTRFKPTRIIYYRDGVSEGQFLNVLNHELKAIREACIKLEMSYQPGITFVVVQKRHHTRLFCSDKKDQMGRSGNIPAGTTVDQIITHPTEFDFYLCSHAGIQGTSRPSHYHVLWDDNRFSADEIQTLTYQLCHTYVRCTRSVSIPAPAYYAHLVAFRARYHLVEKELDSGEGSQKSGNSDERNPTAMMRAVTVHSETLKVMYFA 2784
            F  P RP  GT G+ I+L AN F++ +PK  ++ Y++ I P+KCPRRVNR+++ +MV +      F +++PV+DG+R++YT  PL +    ++L+V LPGEG KDR FKV +K VS VS   L EAL G     P E         V A+DV++RHLPSM YTPVGRSFF     YD+PLGGGREVWFGFHQSVRP+ WKMMLNIDVSATAFYK Q VI FM EVL+I    +  RPLTDS RVKFTKEIKGLKVE+ HCG ++RKYRVCNVTRR A  QTFPLQ E GQT+E TV +YF+++Y ++L++PHLPCLQVGQEQKHTYLPLEVCNIV+GQRCIKKLTD QTSTMIKATARSAPDR++EI+ LVR +N+  DP +Q F   V   MA + GRV+PAP +QYGGR +  ATP  GVWDMRGKQF +G+EIK+WAIACFA QR  RE+ L+ FT QL+KIS DAGMPI GQPCFCKYA G D VEPMFR+LKN++SGLQLI+V+LPGKTPVYAEVKRVGD + G+ATQCVQ KNV K SPQTLSNLCLKINVKLGGIN+ILVP  RP+VF++PVIFLGAD THPPAGD  KPSIAAVVGSMDAHPSRY ATV VQ  RQE IQDLA+MV+ELLIQFYKSTRFKPTRII+YRDGVSEGQF  VL +EL AIREACI LE  YQPGIT++VVQKRHHTRLFC+D+ +++GRSGNIPAGTTVD  ITHP EFDFYLCSHAGIQGTSRPSHYHVLWDDN F+ADE+Q LTYQLCHTYVRCTRSVSIPAPAYYAHLVAFRARYHLV+KE DS EGS  SG S+ R+P A+ +AV +H +TL+ MYFA
Sbjct:   15 FIVPRRPGYGTMGKPIKLLANCFQVEIPKIDVYLYEVDIKPDKCPRRVNREVVDSMVQHFKV-TIFGDRRPVYDGKRSLYTANPLPVATTGVDLDVTLPGEGGKDRPFKVSVKFVSRVSWHLLHEALAGGTLPEPLELDKPVSTNPVHAVDVVLRHLPSMKYTPVGRSFFSAPEGYDHPLGGGREVWFGFHQSVRPAMWKMMLNIDVSATAFYKAQPVIQFMCEVLDIHNIDEQPRPLTDSHRVKFTKEIKGLKVEVTHCGTMRRKYRVCNVTRRPASHQTFPLQLENGQTVERTVAQYFREKYTLQLKYPHLPCLQVGQEQKHTYLPLEVCNIVAGQRCIKKLTDNQTSTMIKATARSAPDRQEEISRLVRSANYETDPFVQEFQFKVRDEMAHVTGRVLPAPMLQYGGRNRTVATPSHGVWDMRGKQFHTGVEIKMWAIACFATQRQCREEILKGFTDQLRKISKDAGMPIQGQPCFCKYAQGADSVEPMFRHLKNTYSGLQLIIVILPGKTPVYAEVKRVGDTLLGMATQCVQVKNVIKTSPQTLSNLCLKINVKLGGINNILVPHQRPSVFQQPVIFLGADVTHPPAGDGKKPSIAAVVGSMDAHPSRYCATVRVQRPRQEIIQDLASMVRELLIQFYKSTRFKPTRIIFYRDGVSEGQFRQVLYYELLAIREACISLEKDYQPGITYIVVQKRHHTRLFCADRTERVGRSGNIPAGTTVDTDITHPYEFDFYLCSHAGIQGTSRPSHYHVLWDDNFFTADELQLLTYQLCHTYVRCTRSVSIPAPAYYAHLVAFRARYHLVDKEHDSAEGSHVSGQSNGRDPQALAKAVQIHQDTLRTMYFA 860

[Close]

BLAST of AGO-2 vs. Ensembl Mouse
Match: Ago4 (argonaute RISC catalytic subunit 4 [Source:MGI Symbol;Acc:MGI:1924100])

HSP 1 Score: 1217.6 bits (3149), Expect = 0.000e+0
Identity = 583/850 (68.59%), Postives = 689/850 (81.06%), Query Frame = 1

Query:  277 FQPPSRPDQGTDGRTIQLKANHFEIVMPKGFLHHYDITITPEKCPRRVNRDIIQAMVNNMHYQKYFYNQKPVFDGRRNMYTREPLSIGKEKLELEVILPGEGKDRVFKVCLKHVSEVSLFALEEALQGRRQTIPAETVTALDVIMRHLPSMTYTPVGRSFFHNTGDYDNPLGGGREVWFGFHQSVRPSQWKMMLNIDVSATAFYKEQSVINFMFEVLEIDK--DLKRPLTDSQRVKFTKEIKGLKVEINHCGPIKRKYRVCNVTRRSAQSQTFPLQSEQGQTIECTVTKYFQDRYGMKLQHPHLPCLQVGQEQKHTYLPLEVCNIVSGQRCIKKLTDMQTSTMIKATARSAPDREKEINNLVRRSNF--NADPHLQIFGVSVNTRMADIQGRVIPAPKIQYGGRTKAQATPQQGVWDMRGKQFFSGIEIKVWAIACFAPQRTVREDSLRTFTQQLQKISNDAGMPIVGQPCFCKYATGQDQVEPMFRYLKNSFSGLQLIVVVLPGKTPVYAEVKRVGDIIFGLATQCVQAKNVNKPSPQTLSNLCLKINVKLGGINSILVPSVRPAVFKEPVIFLGADFTHPPAGDKTKPSIAAVVGSMDAHPSRYAATVSVQPHR----------QETIQDLAAMVKELLIQFYKSTRFKPTRIIYYRDGVSEGQFLNVLNHELKAIREACIKLEMSYQPGITFVVVQKRHHTRLFCSDKKDQMGRSGNIPAGTTVDQIITHPTEFDFYLCSHAGIQGTSRPSHYHVLWDDNRFSADEIQTLTYQLCHTYVRCTRSVSIPAPAYYAHLVAFRARYHLVEKELDSGEGSQKSGNSDERNPTAMMRAVTVHSETLKVMYFA 2784
            FQPP RP  GT G+ I+L ANHF++ +PK  ++HYD+ I PEK PRRVNR+++  MV +   Q  F +++P +DG+RNMYT  PL IG++++++EV LPGEGKD+ FKV ++ VS VSL  L EAL G    +P ++V ALDVI RHLPSM YTPVGRSFF     Y +PLGGGREVWFGFHQSVRP+ W MMLNIDVSATAFY+ Q +I FM EVL+I    +  +PLTDSQRVKFTKEI+GLKVE+ HCG +KRKYRVCNVTRR A  QTFPLQ E GQ +ECTV +YF+ +Y ++L+HPHLPCLQVGQEQKHTYLPLEVCNIV+GQRCIKKLTD QTSTMIKATARSAPDR++EI+ LV+ ++     DP+L+ FG+ V+  M ++ GRV+PAP +QYGGR K  ATP QGVWDMRGKQF++GIEIKVWA+ACFAPQ+  RED L++FT QL+KIS DAGMPI GQPCFCKYA G D VEPMF++LK ++ GLQLIVV+LPGKTPVYAEVKRVGD + G+ATQCVQ KNV K SPQTLSNLCLK+N KLGGIN++LVP  RP+VF++PVIFLGAD THPPAGD  KPSIAAVVGSMD HPSRY ATV VQ  R          QE +QDL +M +ELLIQFYKSTRFKPTRIIYYR GVSEGQ   V   EL AIR+ACI LE  Y+PGIT++VVQKRHHTRLFC+DK +++G+SGN+PAGTTVD  +THP+EFDFYLCSHAGIQGTSRPSHY VLWDDN F+ADE+Q LTYQLCHTYVRCTRSVSIPAPAYYA LVAFRARYHLV+K+ DS EGS  SG S+ R+P A+ +AV +H +T   MYFA
Sbjct:   13 FQPPRRPGLGTVGKPIRLLANHFQVQIPKIDVYHYDVDIKPEKRPRRVNREVVDTMVRHFKMQ-IFGDRQPGYDGKRNMYTAHPLPIGRDRIDMEVTLPGEGKDQTFKVSVQWVSVVSLQLLLEALAGHLNEVPDDSVQALDVITRHLPSMRYTPVGRSFFSPPEGYYHPLGGGREVWFGFHQSVRPAMWNMMLNIDVSATAFYRAQPIIEFMCEVLDIQNINEQTKPLTDSQRVKFTKEIRGLKVEVTHCGQMKRKYRVCNVTRRPASHQTFPLQLENGQAMECTVAQYFKQKYSLQLKHPHLPCLQVGQEQKHTYLPLEVCNIVAGQRCIKKLTDNQTSTMIKATARSAPDRQEEISRLVKSNSMVGGPDPYLKEFGIVVHNEMTELTGRVLPAPMLQYGGRNKTVATPSQGVWDMRGKQFYAGIEIKVWAVACFAPQKQCREDLLKSFTDQLRKISKDAGMPIQGQPCFCKYAQGADSVEPMFKHLKMTYVGLQLIVVILPGKTPVYAEVKRVGDTLLGMATQCVQVKNVVKTSPQTLSNLCLKMNAKLGGINNVLVPHQRPSVFQQPVIFLGADVTHPPAGDGKKPSIAAVVGSMDGHPSRYCATVRVQTSRQEITQELLYSQEVVQDLTSMARELLIQFYKSTRFKPTRIIYYRGGVSEGQMKQVAWPELIAIRKACISLEEDYRPGITYIVVQKRHHTRLFCADKMERVGKSGNVPAGTTVDSTVTHPSEFDFYLCSHAGIQGTSRPSHYQVLWDDNCFTADELQLLTYQLCHTYVRCTRSVSIPAPAYYARLVAFRARYHLVDKDHDSAEGSHVSGQSNGRDPQALAKAVQIHHDTQHTMYFA 861

[Close]

BLAST of AGO-2 vs. Ensembl Mouse
Match: Ago1 (argonaute RISC catalytic subunit 1 [Source:MGI Symbol;Acc:MGI:2446630])

HSP 1 Score: 896.345 bits (2315), Expect = 0.000e+0
Identity = 417/553 (75.41%), Postives = 482/553 (87.16%), Query Frame = 1

Query: 1135 KYFQDRYGMKLQHPHLPCLQVGQEQKHTYLPLEVCNIVSGQRCIKKLTDMQTSTMIKATARSAPDREKEINNLVRRSNFNADPHLQIFGVSVNTRMADIQGRVIPAPKIQYGGR---TKAQATPQQGVWDMRGKQFFSGIEIKVWAIACFAPQRTVREDSLRTFTQQLQKISNDAGMPIVGQPCFCKYATGQDQVEPMFRYLKNSFSGLQLIVVVLPGKTPVYAEVKRVGDIIFGLATQCVQAKNVNKPSPQTLSNLCLKINVKLGGINSILVPSVRPAVFKEPVIFLGADFTHPPAGDKTKPSIAAVVGSMDAHPSRYAATVSVQPHRQETIQDLAAMVKELLIQFYKSTRFKPTRIIYYRDGVSEGQFLNVLNHELKAIREACIKLEMSYQPGITFVVVQKRHHTRLFCSDKKDQMGRSGNIPAGTTVDQIITHPTEFDFYLCSHAGIQGTSRPSHYHVLWDDNRFSADEIQTLTYQLCHTYVRCTRSVSIPAPAYYAHLVAFRARYHLVEKELDSGEGSQKSGNSDERNPTAMMRAVTVHSETLKVMYFA 2784
            +YF+ +Y ++L++PHLPCLQVGQEQKHTYLPLEVCNIV+GQRCIKKLTD QTSTMIKATARSAPDR++EI+ L++ +++N DP++Q FG+ V   M ++ GRV+PAP +QYGGR    +A ATP QGVWDMRGKQF++GIEIKVWAIACFAPQ+  RE+ L+ FT QL+KIS DAGMPI GQPCFCKYA G D VEPMFR+LKN++SGLQLI+V+LPGKTPVYAEVKRVGD + G+ATQCVQ KNV K SPQTLSNLCLKINVKLGGIN+ILVP  R AVF++PVIFLGAD THPPAGD  KPSI AVVGSMDAHPSRY ATV VQ  RQE I+DL+ MV+ELLIQFYKSTRFKPTRII+YRDGV EGQ   +L++EL AIR+ACIKLE  YQPGIT++VVQKRHHTRLFC+DK +++G+SGNIPAGTTVD  ITHP EFDFYLCSHAGIQGTSRPSHY+VLWDDNRF+ADE+Q LTYQLCHTYVRCTRSVSIPAPAYYA LVAFRARYHLV+KE DSGEGS  SG S+ R+P A+ +AV VH +TL+ MYFA
Sbjct:    1 QYFKQKYNLQLKYPHLPCLQVGQEQKHTYLPLEVCNIVAGQRCIKKLTDNQTSTMIKATARSAPDRQEEISRLMKNASYNLDPYIQEFGIKVKDDMTEVTGRVLPAPILQYGGRVSRNRAIATPNQGVWDMRGKQFYNGIEIKVWAIACFAPQKQCREEVLKNFTDQLRKISKDAGMPIQGQPCFCKYAQGADSVEPMFRHLKNTYSGLQLIIVILPGKTPVYAEVKRVGDTLLGMATQCVQVKNVVKTSPQTLSNLCLKINVKLGGINNILVPHQRSAVFQQPVIFLGADVTHPPAGDGKKPSITAVVGSMDAHPSRYCATVRVQRPRQEIIEDLSYMVRELLIQFYKSTRFKPTRIIFYRDGVPEGQLPQILHYELLAIRDACIKLEKDYQPGITYIVVQKRHHTRLFCADKNERIGKSGNIPAGTTVDTNITHPFEFDFYLCSHAGIQGTSRPSHYYVLWDDNRFTADELQILTYQLCHTYVRCTRSVSIPAPAYYARLVAFRARYHLVDKEHDSGEGSHISGQSNGRDPQALAKAVQVHQDTLRTMYFA 553

[Close]

BLAST of AGO-2 vs. UniProt/SwissProt
Match: sp|Q9UKV8|AGO2_HUMAN (Protein argonaute-2 OS=Homo sapiens OX=9606 GN=AGO2 PE=1 SV=3)

HSP 1 Score: 1307.35 bits (3382), Expect = 0.000e+0
Identity = 619/838 (73.87%), Postives = 714/838 (85.20%), Query Frame = 1

Query:  277 FQPPSRPDQGTDGRTIQLKANHFEIVMPKGFLHHYDITITPEKCPRRVNRDIIQAMVNNMHYQKYFYNQKPVFDGRRNMYTREPLSIGKEKLELEVILPGEGKDRVFKVCLKHVSEVSLFALEEALQGRRQTIPAETVTALDVIMRHLPSMTYTPVGRSFFHNTGDYDNPLGGGREVWFGFHQSVRPSQWKMMLNIDVSATAFYKEQSVINFMFEVLEID--KDLKRPLTDSQRVKFTKEIKGLKVEINHCGPIKRKYRVCNVTRRSAQSQTFPLQSEQGQTIECTVTKYFQDRYGMKLQHPHLPCLQVGQEQKHTYLPLEVCNIVSGQRCIKKLTDMQTSTMIKATARSAPDREKEINNLVRRSNFNADPHLQIFGVSVNTRMADIQGRVIPAPKIQYGGRTKAQATPQQGVWDMRGKQFFSGIEIKVWAIACFAPQRTVREDSLRTFTQQLQKISNDAGMPIVGQPCFCKYATGQDQVEPMFRYLKNSFSGLQLIVVVLPGKTPVYAEVKRVGDIIFGLATQCVQAKNVNKPSPQTLSNLCLKINVKLGGINSILVPSVRPAVFKEPVIFLGADFTHPPAGDKTKPSIAAVVGSMDAHPSRYAATVSVQPHRQETIQDLAAMVKELLIQFYKSTRFKPTRIIYYRDGVSEGQFLNVLNHELKAIREACIKLEMSYQPGITFVVVQKRHHTRLFCSDKKDQMGRSGNIPAGTTVDQIITHPTEFDFYLCSHAGIQGTSRPSHYHVLWDDNRFSADEIQTLTYQLCHTYVRCTRSVSIPAPAYYAHLVAFRARYHLVEKELDSGEGSQKSGNSDERNPTAMMRAVTVHSETLKVMYFA 2784
            F+PP RPD GT GRTI+L+AN FE+ +PK  ++HY++ I PEKCPRRVNR+I++ MV +   Q  F ++KPVFDGR+N+YT  PL IG++K+ELEV LPGEGKDR+FKV +K VS VSL AL +AL GR  ++P ET+ ALDV+MRHLPSM YTPVGRSFF  +    NPLGGGREVWFGFHQSVRPS WKMMLNIDVSATAFYK Q VI F+ EVL+    ++ ++PLTDSQRVKFTKEIKGLKVEI HCG +KRKYRVCNVTRR A  QTFPLQ E GQT+ECTV +YF+DR+ + L++PHLPCLQVGQEQKHTYLPLEVCNIV+GQRCIKKLTD QTSTMI+ATARSAPDR++EI+ L+R ++FN DP+++ FG+ V   M D+ GRV+  P I YGGR KA ATP QGVWDMR KQF +GIEIKVWAIACFAPQR   E  L++FT+QL+KIS DAGMPI GQPCFCKYA G D VEPMFR+LKN+++GLQL+VV+LPGKTPVYAEVKRVGD + G+ATQCVQ KNV + +PQTLSNLCLKINVKLGG+N+IL+P  RP VF++PVIFLGAD THPPAGD  KPSIAAVVGSMDAHP+RY ATV VQ HRQE IQDLAAMV+ELLIQFYKSTRFKPTRII+YRDGVSEGQF  VL+HEL AIREACIKLE  YQPGITF+VVQKRHHTRLFC+DK +++G+SGNIPAGTTVD  ITHPTEFDFYLCSHAGIQGTSRPSHYHVLWDDNRFS+DE+Q LTYQLCHTYVRCTRSVSIPAPAYYAHLVAFRARYHLV+KE DS EGS  SG S+ R+  A+ +AV VH +TL+ MYFA
Sbjct:   23 FKPPPRPDFGTSGRTIKLQANFFEMDIPKIDIYHYELDIKPEKCPRRVNREIVEHMVQHFKTQ-IFGDRKPVFDGRKNLYTAMPLPIGRDKVELEVTLPGEGKDRIFKVSIKWVSCVSLQALHDALSGRLPSVPFETIQALDVVMRHLPSMRYTPVGRSFFTASEGCSNPLGGGREVWFGFHQSVRPSLWKMMLNIDVSATAFYKAQPVIEFVCEVLDFKSIEEQQKPLTDSQRVKFTKEIKGLKVEITHCGQMKRKYRVCNVTRRPASHQTFPLQQESGQTVECTVAQYFKDRHKLVLRYPHLPCLQVGQEQKHTYLPLEVCNIVAGQRCIKKLTDNQTSTMIRATARSAPDRQEEISKLMRSASFNTDPYVREFGIMVKDEMTDVTGRVLQPPSILYGGRNKAIATPVQGVWDMRNKQFHTGIEIKVWAIACFAPQRQCTEVHLKSFTEQLRKISRDAGMPIQGQPCFCKYAQGADSVEPMFRHLKNTYAGLQLVVVILPGKTPVYAEVKRVGDTVLGMATQCVQMKNVQRTTPQTLSNLCLKINVKLGGVNNILLPQGRPPVFQQPVIFLGADVTHPPAGDGKKPSIAAVVGSMDAHPNRYCATVRVQQHRQEIIQDLAAMVRELLIQFYKSTRFKPTRIIFYRDGVSEGQFQQVLHHELLAIREACIKLEKDYQPGITFIVVQKRHHTRLFCTDKNERVGKSGNIPAGTTVDTKITHPTEFDFYLCSHAGIQGTSRPSHYHVLWDDNRFSSDELQILTYQLCHTYVRCTRSVSIPAPAYYAHLVAFRARYHLVDKEHDSAEGSHTSGQSNGRDHQALAKAVQVHQDTLRTMYFA 859

[Close]

BLAST of AGO-2 vs. UniProt/SwissProt
Match: sp|Q9QZ81|AGO2_RAT (Protein argonaute-2 OS=Rattus norvegicus OX=10116 GN=Ago2 PE=1 SV=2)

HSP 1 Score: 1306.97 bits (3381), Expect = 0.000e+0
Identity = 619/838 (73.87%), Postives = 714/838 (85.20%), Query Frame = 1

Query:  277 FQPPSRPDQGTDGRTIQLKANHFEIVMPKGFLHHYDITITPEKCPRRVNRDIIQAMVNNMHYQKYFYNQKPVFDGRRNMYTREPLSIGKEKLELEVILPGEGKDRVFKVCLKHVSEVSLFALEEALQGRRQTIPAETVTALDVIMRHLPSMTYTPVGRSFFHNTGDYDNPLGGGREVWFGFHQSVRPSQWKMMLNIDVSATAFYKEQSVINFMFEVLEID--KDLKRPLTDSQRVKFTKEIKGLKVEINHCGPIKRKYRVCNVTRRSAQSQTFPLQSEQGQTIECTVTKYFQDRYGMKLQHPHLPCLQVGQEQKHTYLPLEVCNIVSGQRCIKKLTDMQTSTMIKATARSAPDREKEINNLVRRSNFNADPHLQIFGVSVNTRMADIQGRVIPAPKIQYGGRTKAQATPQQGVWDMRGKQFFSGIEIKVWAIACFAPQRTVREDSLRTFTQQLQKISNDAGMPIVGQPCFCKYATGQDQVEPMFRYLKNSFSGLQLIVVVLPGKTPVYAEVKRVGDIIFGLATQCVQAKNVNKPSPQTLSNLCLKINVKLGGINSILVPSVRPAVFKEPVIFLGADFTHPPAGDKTKPSIAAVVGSMDAHPSRYAATVSVQPHRQETIQDLAAMVKELLIQFYKSTRFKPTRIIYYRDGVSEGQFLNVLNHELKAIREACIKLEMSYQPGITFVVVQKRHHTRLFCSDKKDQMGRSGNIPAGTTVDQIITHPTEFDFYLCSHAGIQGTSRPSHYHVLWDDNRFSADEIQTLTYQLCHTYVRCTRSVSIPAPAYYAHLVAFRARYHLVEKELDSGEGSQKSGNSDERNPTAMMRAVTVHSETLKVMYFA 2784
            F+PP RPD GT GRTI+L+AN FE+ +PK  ++HY++ I PEKCPRRVNR+I++ MV +   Q  F ++KPVFDGR+N+YT  PL IG++K+ELEV LPGEGKDR+FKV +K VS VSL AL +AL GR  ++P ET+ ALDV+MRHLPSM YTPVGRSFF  +    NPLGGGREVWFGFHQSVRPS WKMMLNIDVSATAFYK Q VI F+ EVL+    ++ ++PLTDSQRVKFTKEIKGLKVEI HCG +KRKYRVCNVTRR A  QTFPLQ E GQT+ECTV +YF+DR+ + L++PHLPCLQVGQEQKHTYLPLEVCNIV+GQRCIKKLTD QTSTMI+ATARSAPDR++EI+ L+R ++FN DP+++ FG+ V   M D+ GRV+  P I YGGR KA ATP QGVWDMR KQF +GIEIKVWAIACFAPQR   E  L++FT+QL+KIS DAGMPI GQPCFCKYA G D VEPMFR+LKN+++GLQL+VV+LPGKTPVYAEVKRVGD + G+ATQCVQ KNV + +PQTLSNLCLKINVKLGG+N+IL+P  RP VF++PVIFLGAD THPPAGD  KPSIAAVVGSMDAHP+RY ATV VQ HRQE IQDLAAMV+ELLIQFYKSTRFKPTRII+YRDGVSEGQF  VL+HEL AIREACIKLE  YQPGITF+VVQKRHHTRLFC+DK +++G+SGNIPAGTTVD  ITHPTEFDFYLCSHAGIQGTSRPSHYHVLWDDNRFS+DE+Q LTYQLCHTYVRCTRSVSIPAPAYYAHLVAFRARYHLV+KE DS EGS  SG S+ R+  A+ +AV VH +TL+ MYFA
Sbjct:   24 FKPPPRPDFGTTGRTIKLQANFFEMDIPKIDIYHYELDIKPEKCPRRVNREIVEHMVQHFKTQ-IFGDRKPVFDGRKNLYTAMPLPIGRDKVELEVTLPGEGKDRIFKVSIKWVSCVSLQALHDALSGRLPSVPFETIQALDVVMRHLPSMRYTPVGRSFFTASEGCSNPLGGGREVWFGFHQSVRPSLWKMMLNIDVSATAFYKAQPVIEFVCEVLDFKSIEEQQKPLTDSQRVKFTKEIKGLKVEITHCGQMKRKYRVCNVTRRPASHQTFPLQQESGQTVECTVAQYFKDRHKLVLRYPHLPCLQVGQEQKHTYLPLEVCNIVAGQRCIKKLTDNQTSTMIRATARSAPDRQEEISKLMRSASFNTDPYVREFGIMVKDEMTDVTGRVLQPPSILYGGRNKAIATPVQGVWDMRNKQFHTGIEIKVWAIACFAPQRQCTEVHLKSFTEQLRKISRDAGMPIQGQPCFCKYAQGADSVEPMFRHLKNTYAGLQLVVVILPGKTPVYAEVKRVGDTVLGMATQCVQMKNVQRTTPQTLSNLCLKINVKLGGVNNILLPQGRPPVFQQPVIFLGADVTHPPAGDGKKPSIAAVVGSMDAHPNRYCATVRVQQHRQEIIQDLAAMVRELLIQFYKSTRFKPTRIIFYRDGVSEGQFQQVLHHELLAIREACIKLEKEYQPGITFIVVQKRHHTRLFCTDKNERVGKSGNIPAGTTVDTKITHPTEFDFYLCSHAGIQGTSRPSHYHVLWDDNRFSSDELQILTYQLCHTYVRCTRSVSIPAPAYYAHLVAFRARYHLVDKEHDSAEGSHTSGQSNGRDHQALAKAVQVHQDTLRTMYFA 860

[Close]

BLAST of AGO-2 vs. UniProt/SwissProt
Match: sp|Q8CJG0|AGO2_MOUSE (Protein argonaute-2 OS=Mus musculus OX=10090 GN=Ago2 PE=1 SV=3)

HSP 1 Score: 1306.97 bits (3381), Expect = 0.000e+0
Identity = 619/838 (73.87%), Postives = 714/838 (85.20%), Query Frame = 1

Query:  277 FQPPSRPDQGTDGRTIQLKANHFEIVMPKGFLHHYDITITPEKCPRRVNRDIIQAMVNNMHYQKYFYNQKPVFDGRRNMYTREPLSIGKEKLELEVILPGEGKDRVFKVCLKHVSEVSLFALEEALQGRRQTIPAETVTALDVIMRHLPSMTYTPVGRSFFHNTGDYDNPLGGGREVWFGFHQSVRPSQWKMMLNIDVSATAFYKEQSVINFMFEVLEID--KDLKRPLTDSQRVKFTKEIKGLKVEINHCGPIKRKYRVCNVTRRSAQSQTFPLQSEQGQTIECTVTKYFQDRYGMKLQHPHLPCLQVGQEQKHTYLPLEVCNIVSGQRCIKKLTDMQTSTMIKATARSAPDREKEINNLVRRSNFNADPHLQIFGVSVNTRMADIQGRVIPAPKIQYGGRTKAQATPQQGVWDMRGKQFFSGIEIKVWAIACFAPQRTVREDSLRTFTQQLQKISNDAGMPIVGQPCFCKYATGQDQVEPMFRYLKNSFSGLQLIVVVLPGKTPVYAEVKRVGDIIFGLATQCVQAKNVNKPSPQTLSNLCLKINVKLGGINSILVPSVRPAVFKEPVIFLGADFTHPPAGDKTKPSIAAVVGSMDAHPSRYAATVSVQPHRQETIQDLAAMVKELLIQFYKSTRFKPTRIIYYRDGVSEGQFLNVLNHELKAIREACIKLEMSYQPGITFVVVQKRHHTRLFCSDKKDQMGRSGNIPAGTTVDQIITHPTEFDFYLCSHAGIQGTSRPSHYHVLWDDNRFSADEIQTLTYQLCHTYVRCTRSVSIPAPAYYAHLVAFRARYHLVEKELDSGEGSQKSGNSDERNPTAMMRAVTVHSETLKVMYFA 2784
            F+PP RPD GT GRTI+L+AN FE+ +PK  ++HY++ I PEKCPRRVNR+I++ MV +   Q  F ++KPVFDGR+N+YT  PL IG++K+ELEV LPGEGKDR+FKV +K VS VSL AL +AL GR  ++P ET+ ALDV+MRHLPSM YTPVGRSFF  +    NPLGGGREVWFGFHQSVRPS WKMMLNIDVSATAFYK Q VI F+ EVL+    ++ ++PLTDSQRVKFTKEIKGLKVEI HCG +KRKYRVCNVTRR A  QTFPLQ E GQT+ECTV +YF+DR+ + L++PHLPCLQVGQEQKHTYLPLEVCNIV+GQRCIKKLTD QTSTMI+ATARSAPDR++EI+ L+R ++FN DP+++ FG+ V   M D+ GRV+  P I YGGR KA ATP QGVWDMR KQF +GIEIKVWAIACFAPQR   E  L++FT+QL+KIS DAGMPI GQPCFCKYA G D VEPMFR+LKN+++GLQL+VV+LPGKTPVYAEVKRVGD + G+ATQCVQ KNV + +PQTLSNLCLKINVKLGG+N+IL+P  RP VF++PVIFLGAD THPPAGD  KPSIAAVVGSMDAHP+RY ATV VQ HRQE IQDLAAMV+ELLIQFYKSTRFKPTRII+YRDGVSEGQF  VL+HEL AIREACIKLE  YQPGITF+VVQKRHHTRLFC+DK +++G+SGNIPAGTTVD  ITHPTEFDFYLCSHAGIQGTSRPSHYHVLWDDNRFS+DE+Q LTYQLCHTYVRCTRSVSIPAPAYYAHLVAFRARYHLV+KE DS EGS  SG S+ R+  A+ +AV VH +TL+ MYFA
Sbjct:   24 FKPPPRPDFGTTGRTIKLQANFFEMDIPKIDIYHYELDIKPEKCPRRVNREIVEHMVQHFKTQ-IFGDRKPVFDGRKNLYTAMPLPIGRDKVELEVTLPGEGKDRIFKVSIKWVSCVSLQALHDALSGRLPSVPFETIQALDVVMRHLPSMRYTPVGRSFFTASEGCSNPLGGGREVWFGFHQSVRPSLWKMMLNIDVSATAFYKAQPVIEFVCEVLDFKSIEEQQKPLTDSQRVKFTKEIKGLKVEITHCGQMKRKYRVCNVTRRPASHQTFPLQQESGQTVECTVAQYFKDRHKLVLRYPHLPCLQVGQEQKHTYLPLEVCNIVAGQRCIKKLTDNQTSTMIRATARSAPDRQEEISKLMRSASFNTDPYVREFGIMVKDEMTDVTGRVLQPPSILYGGRNKAIATPVQGVWDMRNKQFHTGIEIKVWAIACFAPQRQCTEVHLKSFTEQLRKISRDAGMPIQGQPCFCKYAQGADSVEPMFRHLKNTYAGLQLVVVILPGKTPVYAEVKRVGDTVLGMATQCVQMKNVQRTTPQTLSNLCLKINVKLGGVNNILLPQGRPPVFQQPVIFLGADVTHPPAGDGKKPSIAAVVGSMDAHPNRYCATVRVQQHRQEIIQDLAAMVRELLIQFYKSTRFKPTRIIFYRDGVSEGQFQQVLHHELLAIREACIKLEKDYQPGITFIVVQKRHHTRLFCTDKNERVGKSGNIPAGTTVDTKITHPTEFDFYLCSHAGIQGTSRPSHYHVLWDDNRFSSDELQILTYQLCHTYVRCTRSVSIPAPAYYAHLVAFRARYHLVDKEHDSAEGSHTSGQSNGRDHQALAKAVQVHQDTLRTMYFA 860

[Close]

BLAST of AGO-2 vs. UniProt/SwissProt
Match: sp|O77503|AGO2_RABIT (Protein argonaute-2 (Fragment) OS=Oryctolagus cuniculus OX=9986 GN=AGO2 PE=1 SV=2)

HSP 1 Score: 1305.81 bits (3378), Expect = 0.000e+0
Identity = 619/838 (73.87%), Postives = 713/838 (85.08%), Query Frame = 1

Query:  277 FQPPSRPDQGTDGRTIQLKANHFEIVMPKGFLHHYDITITPEKCPRRVNRDIIQAMVNNMHYQKYFYNQKPVFDGRRNMYTREPLSIGKEKLELEVILPGEGKDRVFKVCLKHVSEVSLFALEEALQGRRQTIPAETVTALDVIMRHLPSMTYTPVGRSFFHNTGDYDNPLGGGREVWFGFHQSVRPSQWKMMLNIDVSATAFYKEQSVINFMFEVLEID--KDLKRPLTDSQRVKFTKEIKGLKVEINHCGPIKRKYRVCNVTRRSAQSQTFPLQSEQGQTIECTVTKYFQDRYGMKLQHPHLPCLQVGQEQKHTYLPLEVCNIVSGQRCIKKLTDMQTSTMIKATARSAPDREKEINNLVRRSNFNADPHLQIFGVSVNTRMADIQGRVIPAPKIQYGGRTKAQATPQQGVWDMRGKQFFSGIEIKVWAIACFAPQRTVREDSLRTFTQQLQKISNDAGMPIVGQPCFCKYATGQDQVEPMFRYLKNSFSGLQLIVVVLPGKTPVYAEVKRVGDIIFGLATQCVQAKNVNKPSPQTLSNLCLKINVKLGGINSILVPSVRPAVFKEPVIFLGADFTHPPAGDKTKPSIAAVVGSMDAHPSRYAATVSVQPHRQETIQDLAAMVKELLIQFYKSTRFKPTRIIYYRDGVSEGQFLNVLNHELKAIREACIKLEMSYQPGITFVVVQKRHHTRLFCSDKKDQMGRSGNIPAGTTVDQIITHPTEFDFYLCSHAGIQGTSRPSHYHVLWDDNRFSADEIQTLTYQLCHTYVRCTRSVSIPAPAYYAHLVAFRARYHLVEKELDSGEGSQKSGNSDERNPTAMMRAVTVHSETLKVMYFA 2784
            F+PP RPD GT GRTI+L+AN FE+ +PK  ++HY++ I PEKCPRRVNR+I++ MV +   Q  F ++KPVFDGR+N+YT  PL IG+EK+ELEV LPGEGKDR+FKV +K VS VSL AL +AL GR  ++P ET+ ALDV+MRHLPSM YTPVGRSFF  +    NPLGGGREVWFGFHQSVRPS WKMMLNIDVSATAFYK Q VI F+ EVL+    ++ ++PLTDSQRVKFTKEIKGLKVEI HCG +KRKYRVCNVTRR A  QTFPLQ E GQT+ECTV +YF+DR+ + L++PHLPCLQVGQEQKHTYLPLEVCNIV+GQRCIKKLTD QTSTMI+ATARSAPDR++EI+ L+R ++FN DP+++ FG+ V   M D+ GRV+  P I YGGR KA ATP QGVWDMR KQF +GIEIKVWAIACFAPQR   E  L++FT+QL+KIS DAGMPI GQPCFCKYA G D V PMFR+LKN+++GLQL+VV+LPGKTPVYAEVKRVGD + G+ATQCVQ KNV + +PQTLSNLCLKINVKLGG+N+IL+P  RP VF++PVIFLGAD THPPAGD  KPSIAAVVGSMDAHP+RY ATV VQ HRQE IQDLAAMV+ELLIQFYKSTRFKPTRII+YRDGVSEGQF  VL+HEL AIREACIKLE  YQPGITF+VVQKRHHTRLFC+DK +++G+SGNIPAGTTVD  ITHPTEFDFYLCSHAGIQGTSRPSHYHVLWDDNRFS+DE+Q LTYQLCHTYVRCTRSVSIPAPAYYAHLVAFRARYHLV+KE DS EGS  SG S+ R+  A+ +AV VH +TL+ MYFA
Sbjct:    4 FKPPPRPDFGTSGRTIKLQANFFEMDIPKIDIYHYELDIKPEKCPRRVNREIVEHMVQHFKAQ-IFGDRKPVFDGRKNLYTAMPLPIGREKVELEVTLPGEGKDRIFKVSIKWVSCVSLQALHDALSGRLPSVPFETIQALDVVMRHLPSMRYTPVGRSFFTASEGCSNPLGGGREVWFGFHQSVRPSLWKMMLNIDVSATAFYKAQPVIEFVCEVLDFKSIEEQQKPLTDSQRVKFTKEIKGLKVEITHCGQMKRKYRVCNVTRRPASHQTFPLQQESGQTVECTVAQYFKDRHKLVLRYPHLPCLQVGQEQKHTYLPLEVCNIVAGQRCIKKLTDNQTSTMIRATARSAPDRQEEISKLMRSASFNTDPYVREFGIMVKDEMTDVTGRVLQPPSILYGGRNKAIATPVQGVWDMRNKQFHTGIEIKVWAIACFAPQRQCTEVHLKSFTEQLRKISRDAGMPIQGQPCFCKYAQGADSVGPMFRHLKNTYAGLQLVVVILPGKTPVYAEVKRVGDTVLGMATQCVQMKNVQRTTPQTLSNLCLKINVKLGGVNNILLPQGRPPVFQQPVIFLGADVTHPPAGDGKKPSIAAVVGSMDAHPNRYCATVRVQQHRQEIIQDLAAMVRELLIQFYKSTRFKPTRIIFYRDGVSEGQFQQVLHHELLAIREACIKLEKDYQPGITFIVVQKRHHTRLFCTDKNERVGKSGNIPAGTTVDTKITHPTEFDFYLCSHAGIQGTSRPSHYHVLWDDNRFSSDELQILTYQLCHTYVRCTRSVSIPAPAYYAHLVAFRARYHLVDKEHDSAEGSHTSGQSNGRDHQALAKAVQVHQDTLRTMYFA 840

[Close]

BLAST of AGO-2 vs. UniProt/SwissProt
Match: sp|Q6QME8|AGO2_BOVIN (Protein argonaute-2 OS=Bos taurus OX=9913 GN=AGO2 PE=2 SV=1)

HSP 1 Score: 1303.12 bits (3371), Expect = 0.000e+0
Identity = 618/838 (73.75%), Postives = 713/838 (85.08%), Query Frame = 1

Query:  277 FQPPSRPDQGTDGRTIQLKANHFEIVMPKGFLHHYDITITPEKCPRRVNRDIIQAMVNNMHYQKYFYNQKPVFDGRRNMYTREPLSIGKEKLELEVILPGEGKDRVFKVCLKHVSEVSLFALEEALQGRRQTIPAETVTALDVIMRHLPSMTYTPVGRSFFHNTGDYDNPLGGGREVWFGFHQSVRPSQWKMMLNIDVSATAFYKEQSVINFMFEVLEID--KDLKRPLTDSQRVKFTKEIKGLKVEINHCGPIKRKYRVCNVTRRSAQSQTFPLQSEQGQTIECTVTKYFQDRYGMKLQHPHLPCLQVGQEQKHTYLPLEVCNIVSGQRCIKKLTDMQTSTMIKATARSAPDREKEINNLVRRSNFNADPHLQIFGVSVNTRMADIQGRVIPAPKIQYGGRTKAQATPQQGVWDMRGKQFFSGIEIKVWAIACFAPQRTVREDSLRTFTQQLQKISNDAGMPIVGQPCFCKYATGQDQVEPMFRYLKNSFSGLQLIVVVLPGKTPVYAEVKRVGDIIFGLATQCVQAKNVNKPSPQTLSNLCLKINVKLGGINSILVPSVRPAVFKEPVIFLGADFTHPPAGDKTKPSIAAVVGSMDAHPSRYAATVSVQPHRQETIQDLAAMVKELLIQFYKSTRFKPTRIIYYRDGVSEGQFLNVLNHELKAIREACIKLEMSYQPGITFVVVQKRHHTRLFCSDKKDQMGRSGNIPAGTTVDQIITHPTEFDFYLCSHAGIQGTSRPSHYHVLWDDNRFSADEIQTLTYQLCHTYVRCTRSVSIPAPAYYAHLVAFRARYHLVEKELDSGEGSQKSGNSDERNPTAMMRAVTVHSETLKVMYFA 2784
            F+PP RPD GT GRTI+L+AN FE+ +PK  ++HY++ I PEKCPRRVNR+I++ MV +   Q  F ++KPVFDGR+N+YT  PL IG++K+ELEV LPGEGKDR+FKV +K VS VSL AL +AL GR  ++P ET+ ALDV+MRHLPSM YTPVGRSFF  +    NPLGGGREVWFGFHQSVRPS WKMMLNIDVSATAFYK Q VI F+ EVL+    ++ ++PLTDSQRVKFTKEIKGLKVEI HCG +KRKYRVCNVTRR A  QTFPLQ E GQT+ECTV +YF+DR+ + L++PHLPCLQVGQEQKHTYLPLEVCNIV+GQRCIKKLTD QTSTMI+ATARSAPDR++EI+ L+R ++FN DP+++ FG+ V   M D+ GRV+  P I YGGR KA ATP QGVWDMR KQF +GIEIKVWAIACFAPQR   E  L++FT+QL+KIS DAGMPI GQPCFCKYA G D VEPMFR+LKN+++GLQL+VV+LPGKTPVYAEVKRVGD + G+ATQCVQ KNV + +PQTLSNL LKINVKLGG+N+IL+P  RP VF++PVIFLGAD THPPAGD  KPSIAAVVGSMDAHP+RY ATV VQ HRQE IQDLAAMV+ELLIQFYKSTRFKPTRII+YRDGVSEGQF  VL+HEL AIREACIKLE  YQPGITF+VVQKRHHTRLFC+DK +++G+SGNIPAGTTVD  ITHPTEFDFYLCSHAGIQGTSRPSHYHVLWDDNRFS+DE+Q LTYQLCHTYVRCTRSVSIPAPAYYAHLVAFRARYHLV+KE DS EGS  SG S+ R+  A+ +AV VH +TL+ MYFA
Sbjct:   24 FKPPPRPDFGTSGRTIKLQANFFEMDIPKIDIYHYELDIKPEKCPRRVNREIVEHMVQHFKTQ-IFGDRKPVFDGRKNLYTAMPLPIGRDKVELEVTLPGEGKDRIFKVSIKWVSCVSLQALHDALSGRLPSVPFETIQALDVVMRHLPSMRYTPVGRSFFTASEGCSNPLGGGREVWFGFHQSVRPSLWKMMLNIDVSATAFYKAQPVIEFVCEVLDFKSIEEQQKPLTDSQRVKFTKEIKGLKVEITHCGQMKRKYRVCNVTRRPASHQTFPLQQESGQTVECTVAQYFKDRHKLVLRYPHLPCLQVGQEQKHTYLPLEVCNIVAGQRCIKKLTDNQTSTMIRATARSAPDRQEEISKLMRSASFNTDPYVREFGIMVKDEMTDVTGRVLQPPSILYGGRNKAIATPVQGVWDMRNKQFHTGIEIKVWAIACFAPQRQCTEVHLKSFTEQLRKISRDAGMPIQGQPCFCKYAQGADSVEPMFRHLKNTYAGLQLVVVILPGKTPVYAEVKRVGDTVLGMATQCVQMKNVQRTTPQTLSNLWLKINVKLGGVNNILLPQGRPPVFQQPVIFLGADVTHPPAGDGKKPSIAAVVGSMDAHPNRYCATVRVQQHRQEIIQDLAAMVRELLIQFYKSTRFKPTRIIFYRDGVSEGQFQQVLHHELLAIREACIKLEKDYQPGITFIVVQKRHHTRLFCTDKNERVGKSGNIPAGTTVDTKITHPTEFDFYLCSHAGIQGTSRPSHYHVLWDDNRFSSDELQILTYQLCHTYVRCTRSVSIPAPAYYAHLVAFRARYHLVDKEHDSAEGSHTSGQSNGRDHQALAKAVQVHQDTLRTMYFA 860

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BLAST of AGO-2 vs. TrEMBL
Match: F8TJX6 (AGO-2 OS=Schmidtea mediterranea OX=79327 PE=2 SV=1)

HSP 1 Score: 1889 bits (4892), Expect = 0.000e+0
Identity = 928/928 (100.00%), Postives = 928/928 (100.00%), Query Frame = 1

Query:    1 MLGGTYFTPPTYLFXXXXXXXXXXAILGLAATPNGNQTMNPLGAPGQPPNTSVPAIIGSTQLSSNISSGPSPPQLPTXXXXXXXXXXXXXVYFQPPSRPDQGTDGRTIQLKANHFEIVMPKGFLHHYDITITPEKCPRRVNRDIIQAMVNNMHYQKYFYNQKPVFDGRRNMYTREPLSIGKEKLELEVILPGEGKDRVFKVCLKHVSEVSLFALEEALQGRRQTIPAETVTALDVIMRHLPSMTYTPVGRSFFHNTGDYDNPLGGGREVWFGFHQSVRPSQWKMMLNIDVSATAFYKEQSVINFMFEVLEIDKDLKRPLTDSQRVKFTKEIKGLKVEINHCGPIKRKYRVCNVTRRSAQSQTFPLQSEQGQTIECTVTKYFQDRYGMKLQHPHLPCLQVGQEQKHTYLPLEVCNIVSGQRCIKKLTDMQTSTMIKATARSAPDREKEINNLVRRSNFNADPHLQIFGVSVNTRMADIQGRVIPAPKIQYGGRTKAQATPQQGVWDMRGKQFFSGIEIKVWAIACFAPQRTVREDSLRTFTQQLQKISNDAGMPIVGQPCFCKYATGQDQVEPMFRYLKNSFSGLQLIVVVLPGKTPVYAEVKRVGDIIFGLATQCVQAKNVNKPSPQTLSNLCLKINVKLGGINSILVPSVRPAVFKEPVIFLGADFTHPPAGDKTKPSIAAVVGSMDAHPSRYAATVSVQPHRQETIQDLAAMVKELLIQFYKSTRFKPTRIIYYRDGVSEGQFLNVLNHELKAIREACIKLEMSYQPGITFVVVQKRHHTRLFCSDKKDQMGRSGNIPAGTTVDQIITHPTEFDFYLCSHAGIQGTSRPSHYHVLWDDNRFSADEIQTLTYQLCHTYVRCTRSVSIPAPAYYAHLVAFRARYHLVEKELDSGEGSQKSGNSDERNPTAMMRAVTVHSETLKVMYFA 2784
            MLGGTYFTPPTYLFNSNGNNENNSAILGLAATPNGNQTMNPLGAPGQPPNTSVPAIIGSTQLSSNISSGPSPPQLPTGSNSQYSSSGNGSVYFQPPSRPDQGTDGRTIQLKANHFEIVMPKGFLHHYDITITPEKCPRRVNRDIIQAMVNNMHYQKYFYNQKPVFDGRRNMYTREPLSIGKEKLELEVILPGEGKDRVFKVCLKHVSEVSLFALEEALQGRRQTIPAETVTALDVIMRHLPSMTYTPVGRSFFHNTGDYDNPLGGGREVWFGFHQSVRPSQWKMMLNIDVSATAFYKEQSVINFMFEVLEIDKDLKRPLTDSQRVKFTKEIKGLKVEINHCGPIKRKYRVCNVTRRSAQSQTFPLQSEQGQTIECTVTKYFQDRYGMKLQHPHLPCLQVGQEQKHTYLPLEVCNIVSGQRCIKKLTDMQTSTMIKATARSAPDREKEINNLVRRSNFNADPHLQIFGVSVNTRMADIQGRVIPAPKIQYGGRTKAQATPQQGVWDMRGKQFFSGIEIKVWAIACFAPQRTVREDSLRTFTQQLQKISNDAGMPIVGQPCFCKYATGQDQVEPMFRYLKNSFSGLQLIVVVLPGKTPVYAEVKRVGDIIFGLATQCVQAKNVNKPSPQTLSNLCLKINVKLGGINSILVPSVRPAVFKEPVIFLGADFTHPPAGDKTKPSIAAVVGSMDAHPSRYAATVSVQPHRQETIQDLAAMVKELLIQFYKSTRFKPTRIIYYRDGVSEGQFLNVLNHELKAIREACIKLEMSYQPGITFVVVQKRHHTRLFCSDKKDQMGRSGNIPAGTTVDQIITHPTEFDFYLCSHAGIQGTSRPSHYHVLWDDNRFSADEIQTLTYQLCHTYVRCTRSVSIPAPAYYAHLVAFRARYHLVEKELDSGEGSQKSGNSDERNPTAMMRAVTVHSETLKVMYFA
Sbjct:    1 MLGGTYFTPPTYLFNSNGNNENNSAILGLAATPNGNQTMNPLGAPGQPPNTSVPAIIGSTQLSSNISSGPSPPQLPTGSNSQYSSSGNGSVYFQPPSRPDQGTDGRTIQLKANHFEIVMPKGFLHHYDITITPEKCPRRVNRDIIQAMVNNMHYQKYFYNQKPVFDGRRNMYTREPLSIGKEKLELEVILPGEGKDRVFKVCLKHVSEVSLFALEEALQGRRQTIPAETVTALDVIMRHLPSMTYTPVGRSFFHNTGDYDNPLGGGREVWFGFHQSVRPSQWKMMLNIDVSATAFYKEQSVINFMFEVLEIDKDLKRPLTDSQRVKFTKEIKGLKVEINHCGPIKRKYRVCNVTRRSAQSQTFPLQSEQGQTIECTVTKYFQDRYGMKLQHPHLPCLQVGQEQKHTYLPLEVCNIVSGQRCIKKLTDMQTSTMIKATARSAPDREKEINNLVRRSNFNADPHLQIFGVSVNTRMADIQGRVIPAPKIQYGGRTKAQATPQQGVWDMRGKQFFSGIEIKVWAIACFAPQRTVREDSLRTFTQQLQKISNDAGMPIVGQPCFCKYATGQDQVEPMFRYLKNSFSGLQLIVVVLPGKTPVYAEVKRVGDIIFGLATQCVQAKNVNKPSPQTLSNLCLKINVKLGGINSILVPSVRPAVFKEPVIFLGADFTHPPAGDKTKPSIAAVVGSMDAHPSRYAATVSVQPHRQETIQDLAAMVKELLIQFYKSTRFKPTRIIYYRDGVSEGQFLNVLNHELKAIREACIKLEMSYQPGITFVVVQKRHHTRLFCSDKKDQMGRSGNIPAGTTVDQIITHPTEFDFYLCSHAGIQGTSRPSHYHVLWDDNRFSADEIQTLTYQLCHTYVRCTRSVSIPAPAYYAHLVAFRARYHLVEKELDSGEGSQKSGNSDERNPTAMMRAVTVHSETLKVMYFA 928

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BLAST of AGO-2 vs. TrEMBL
Match: D5JG45 (Argonaute-2 (Fragment) OS=Dugesia japonica OX=6161 GN=AGO-2 PE=2 SV=1)

HSP 1 Score: 1856.26 bits (4807), Expect = 0.000e+0
Identity = 910/917 (99.24%), Postives = 914/917 (99.67%), Query Frame = 1

Query:   34 YLFXXXXXXXXXXAILGLAATPNGNQTMNPLGAPGQPPNTSVPAIIGSTQLSSNISSGPSPPQLPTXXXXXXXXXXXXXVYFQPPSRPDQGTDGRTIQLKANHFEIVMPKGFLHHYDITITPEKCPRRVNRDIIQAMVNNMHYQKYFYNQKPVFDGRRNMYTREPLSIGKEKLELEVILPGEGKDRVFKVCLKHVSEVSLFALEEALQGRRQTIPAETVTALDVIMRHLPSMTYTPVGRSFFHNTGDYDNPLGGGREVWFGFHQSVRPSQWKMMLNIDVSATAFYKEQSVINFMFEVLEIDKDLKRPLTDSQRVKFTKEIKGLKVEINHCGPIKRKYRVCNVTRRSAQSQTFPLQSEQGQTIECTVTKYFQDRYGMKLQHPHLPCLQVGQEQKHTYLPLEVCNIVSGQRCIKKLTDMQTSTMIKATARSAPDREKEINNLVRRSNFNADPHLQIFGVSVNTRMADIQGRVIPAPKIQYGGRTKAQATPQQGVWDMRGKQFFSGIEIKVWAIACFAPQRTVREDSLRTFTQQLQKISNDAGMPIVGQPCFCKYATGQDQVEPMFRYLKNSFSGLQLIVVVLPGKTPVYAEVKRVGDIIFGLATQCVQAKNVNKPSPQTLSNLCLKINVKLGGINSILVPSVRPAVFKEPVIFLGADFTHPPAGDKTKPSIAAVVGSMDAHPSRYAATVSVQPHRQETIQDLAAMVKELLIQFYKSTRFKPTRIIYYRDGVSEGQFLNVLNHELKAIREACIKLEMSYQPGITFVVVQKRHHTRLFCSDKKDQMGRSGNIPAGTTVDQIITHPTEFDFYLCSHAGIQGTSRPSHYHVLWDDNRFSADEIQTLTYQLCHTYVRCTRSVSIPAPAYYAHLVAFRARYHLVEKELDSGEGSQKSGNSDERNPTAMMRAVTVHSETLKVMYFA 2784
            YLFNSNGN+ENN+  L LA+TPNGNQTMNPLGAPGQPPNTSVPAIIGSTQLSSN+SSGPSPPQLPTGSNSQYSSSGNGSVYFQPPSRPDQGTDGRTIQLKANHFEIVMPKGFLHHYDITITPEKCPRRVNRDIIQAMVNNMHYQKYFYNQKPVFDGRRNMYTREPLSIGKEKLELEVILPGEGKDRVFKVCLKHVSEVSLFALEEALQGRRQTIPAETVTALDVIMRHLPSMTYTPVGRSFFHNTGDYDNPLGGGREVWFGFHQSVRPSQWKMMLNIDVSATAFYKEQSVINFMFEVLEIDKDLKRPLTDSQRVKFTKEIKGLKVEINHCGPIKRKYRVCNVTRRSAQSQTFPLQSEQGQTIECTVTKYFQDRYGMKLQHPHLPCLQVGQEQKHTYLPLEVCNIVSGQRCIKKLTDMQTSTMIKATARSAPDREKEINNLVRRSNFNADPHLQIFGVSVNTRMADIQGRVIPAPKIQYGGRTKAQATPQQGVWDMRGKQFFSGIEIKVWAIACFAPQRTVREDSLRTFTQQLQKISNDAGMPIVGQPCFCKYATGQDQVEPMFRYLKNSFSGLQLIVVVLPGKTPVYAEVKRVGDIIFGLATQCVQAKNVNKPSPQTLSNLCLKINVKLGGINSILVPSVRPAVFKEPVIFLGADFTHPPAGDKTKPSIAAVVGSMDAHPSRYAATVSVQPHRQETIQDLAAMVKELLIQFYKSTRFKPTRIIYYRDGVSEGQFLNVLNHELKAIREACIKLEMSYQPGITFVVVQKRHHTRLFCSDKKDQMGRSGNIPAGTTVDQIITHPTEFDFYLCSHAGIQGTSRPSHYHVLWDDNRFSADEIQTLTYQLCHTYVRCTRSVSIPAPAYYAHLVAFRARYHLVEKELDSGEGSQKSGNSDERNPTAMMRAVTVHSETLKVMYFA
Sbjct:    1 YLFNSNGNSENNNNSLCLASTPNGNQTMNPLGAPGQPPNTSVPAIIGSTQLSSNLSSGPSPPQLPTGSNSQYSSSGNGSVYFQPPSRPDQGTDGRTIQLKANHFEIVMPKGFLHHYDITITPEKCPRRVNRDIIQAMVNNMHYQKYFYNQKPVFDGRRNMYTREPLSIGKEKLELEVILPGEGKDRVFKVCLKHVSEVSLFALEEALQGRRQTIPAETVTALDVIMRHLPSMTYTPVGRSFFHNTGDYDNPLGGGREVWFGFHQSVRPSQWKMMLNIDVSATAFYKEQSVINFMFEVLEIDKDLKRPLTDSQRVKFTKEIKGLKVEINHCGPIKRKYRVCNVTRRSAQSQTFPLQSEQGQTIECTVTKYFQDRYGMKLQHPHLPCLQVGQEQKHTYLPLEVCNIVSGQRCIKKLTDMQTSTMIKATARSAPDREKEINNLVRRSNFNADPHLQIFGVSVNTRMADIQGRVIPAPKIQYGGRTKAQATPQQGVWDMRGKQFFSGIEIKVWAIACFAPQRTVREDSLRTFTQQLQKISNDAGMPIVGQPCFCKYATGQDQVEPMFRYLKNSFSGLQLIVVVLPGKTPVYAEVKRVGDIIFGLATQCVQAKNVNKPSPQTLSNLCLKINVKLGGINSILVPSVRPAVFKEPVIFLGADFTHPPAGDKTKPSIAAVVGSMDAHPSRYAATVSVQPHRQETIQDLAAMVKELLIQFYKSTRFKPTRIIYYRDGVSEGQFLNVLNHELKAIREACIKLEMSYQPGITFVVVQKRHHTRLFCSDKKDQMGRSGNIPAGTTVDQIITHPTEFDFYLCSHAGIQGTSRPSHYHVLWDDNRFSADEIQTLTYQLCHTYVRCTRSVSIPAPAYYAHLVAFRARYHLVEKELDSGEGSQKSGNSDERNPTAMMRAVTVHSETLKVMYFA 917

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BLAST of AGO-2 vs. TrEMBL
Match: A0A4S2LHY1 (Uncharacterized protein OS=Opisthorchis felineus OX=147828 GN=CRM22_007061 PE=3 SV=1)

HSP 1 Score: 1545.79 bits (4001), Expect = 0.000e+0
Identity = 720/840 (85.71%), Postives = 786/840 (93.57%), Query Frame = 1

Query:  271 VYFQPPSRPDQGTDGRTIQLKANHFEIVMPKGFLHHYDITITPEKCPRRVNRDIIQAMVNNMHYQKYFYNQKPVFDGRRNMYTREPLSIGKEKLELEVILPGEGKDRVFKVCLKHVSEVSLFALEEALQGRRQTIPAETVTALDVIMRHLPSMTYTPVGRSFFHNTGDYDNPLGGGREVWFGFHQSVRPSQWKMMLNIDVSATAFYKEQSVINFMFEVLEI-DK-DLKRPLTDSQRVKFTKEIKGLKVEINHCGPIKRKYRVCNVTRRSAQSQTFPLQSEQGQTIECTVTKYFQDRYGMKLQHPHLPCLQVGQEQKHTYLPLEVCNIVSGQRCIKKLTDMQTSTMIKATARSAPDREKEINNLVRRSNFNADPHLQIFGVSVNTRMADIQGRVIPAPKIQYGGRTKAQATPQQGVWDMRGKQFFSGIEIKVWAIACFAPQRTVREDSLRTFTQQLQKISNDAGMPIVGQPCFCKYATGQDQVEPMFRYLKNSFSGLQLIVVVLPGKTPVYAEVKRVGDIIFGLATQCVQAKNVNKPSPQTLSNLCLKINVKLGGINSILVPSVRPAVFKEPVIFLGADFTHPPAGDKTKPSIAAVVGSMDAHPSRYAATVSVQPHRQETIQDLAAMVKELLIQFYKSTRFKPTRIIYYRDGVSEGQFLNVLNHELKAIREACIKLEMSYQPGITFVVVQKRHHTRLFCSDKKDQMGRSGNIPAGTTVDQIITHPTEFDFYLCSHAGIQGTSRPSHYHVLWDDNRFSADEIQTLTYQLCHTYVRCTRSVSIPAPAYYAHLVAFRARYHLVEKELDSGEGSQKSGNSDERNPTAMMRAVTVHSETLKVMYFA 2784
            + F+PP+RP +G+DGR I L+ANHFEI MPKGFLHHYD++I PEKCPRRVNR+II+ MVN+MHYQKYFYNQKPVFDGRRNMYTR+PL I KEK+ELEV LPGEGKDRVF+V +KHVSEVSLFALEEAL G  + IP + V +LDVIMRHLPSM+YTPVGRSFF N   Y+NPLGGGREVWFGFHQSVRPSQW+MMLNIDVSATAFYK QSVI+FM EVL+I DK + +R LTDSQRVKFTKEIKGLKVEI HCG ++RKYRVCNVTRR A +Q+FPLQ E G T+ECTV KYFQ+RY ++L++PHLPCLQVGQEQKHTYLPLEVCN+V+GQRCIKKLTDMQTSTMIKATARSAPDREKEINNLV+R+NFNADPHLQ+FG++VNTRMA+IQGRVIPAPKIQYGGRTKAQA+PQ GVWDMRGKQFFSGIEIKVWAIACFAPQR VREDSLR FT QLQKISNDAGMPI+ QPCFCKYATGQDQVEPMFRYLKN+ +GLQLIVVVLPGKTPVYAEVKRVGDI+FGLATQCVQ+KNVNK SPQTLSNLCLKINVKLGGINSI+VPSVRPAVF+EPVIFLGAD THPPAGDKTKPSIAAVV SMDAHPSRY+ATV VQPHRQE IQDL  MVK+LL+QFY++TRFKPTRIIYYRDGVSEGQFLNVLNHEL+AIREAC+KLE+ YQPGITF+VVQKRHHTRLFC+DKKDQMG+SGNIPAGTTVDQ+ITHPTEFDFYLCSHAGIQGTSRPSHYHVLWDDNRFSAD+IQ LTYQLCHTYVRCTRSVSIPAPAYYAHLVAFRARYHLVEKE+DSGEGSQKSGNSDER PTAMMRAVTVH ETL+VMYFA
Sbjct:  174 IQFEPPARPGRGSDGRAISLRANHFEIRMPKGFLHHYDVSIVPEKCPRRVNREIIETMVNSMHYQKYFYNQKPVFDGRRNMYTRDPLPISKEKVELEVTLPGEGKDRVFRVAIKHVSEVSLFALEEALGGHIRHIPNDAVVSLDVIMRHLPSMSYTPVGRSFFQNPDGYENPLGGGREVWFGFHQSVRPSQWRMMLNIDVSATAFYKAQSVIDFMCEVLDISDKSEQRRALTDSQRVKFTKEIKGLKVEITHCGTMRRKYRVCNVTRRPAHTQSFPLQLETGATMECTVAKYFQERYNIRLEYPHLPCLQVGQEQKHTYLPLEVCNMVAGQRCIKKLTDMQTSTMIKATARSAPDREKEINNLVKRANFNADPHLQMFGINVNTRMAEIQGRVIPAPKIQYGGRTKAQASPQLGVWDMRGKQFFSGIEIKVWAIACFAPQRIVREDSLRLFTLQLQKISNDAGMPILAQPCFCKYATGQDQVEPMFRYLKNTHAGLQLIVVVLPGKTPVYAEVKRVGDIMFGLATQCVQSKNVNKTSPQTLSNLCLKINVKLGGINSIIVPSVRPAVFREPVIFLGADVTHPPAGDKTKPSIAAVVASMDAHPSRYSATVRVQPHRQEIIQDLYPMVKDLLLQFYRATRFKPTRIIYYRDGVSEGQFLNVLNHELRAIREACVKLELGYQPGITFIVVQKRHHTRLFCADKKDQMGKSGNIPAGTTVDQVITHPTEFDFYLCSHAGIQGTSRPSHYHVLWDDNRFSADDIQNLTYQLCHTYVRCTRSVSIPAPAYYAHLVAFRARYHLVEKEIDSGEGSQKSGNSDERTPTAMMRAVTVHPETLRVMYFA 1013

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BLAST of AGO-2 vs. TrEMBL
Match: A0A074ZUU8 (Uncharacterized protein OS=Opisthorchis viverrini OX=6198 GN=T265_02735 PE=3 SV=1)

HSP 1 Score: 1545.79 bits (4001), Expect = 0.000e+0
Identity = 720/840 (85.71%), Postives = 786/840 (93.57%), Query Frame = 1

Query:  271 VYFQPPSRPDQGTDGRTIQLKANHFEIVMPKGFLHHYDITITPEKCPRRVNRDIIQAMVNNMHYQKYFYNQKPVFDGRRNMYTREPLSIGKEKLELEVILPGEGKDRVFKVCLKHVSEVSLFALEEALQGRRQTIPAETVTALDVIMRHLPSMTYTPVGRSFFHNTGDYDNPLGGGREVWFGFHQSVRPSQWKMMLNIDVSATAFYKEQSVINFMFEVLEI-DK-DLKRPLTDSQRVKFTKEIKGLKVEINHCGPIKRKYRVCNVTRRSAQSQTFPLQSEQGQTIECTVTKYFQDRYGMKLQHPHLPCLQVGQEQKHTYLPLEVCNIVSGQRCIKKLTDMQTSTMIKATARSAPDREKEINNLVRRSNFNADPHLQIFGVSVNTRMADIQGRVIPAPKIQYGGRTKAQATPQQGVWDMRGKQFFSGIEIKVWAIACFAPQRTVREDSLRTFTQQLQKISNDAGMPIVGQPCFCKYATGQDQVEPMFRYLKNSFSGLQLIVVVLPGKTPVYAEVKRVGDIIFGLATQCVQAKNVNKPSPQTLSNLCLKINVKLGGINSILVPSVRPAVFKEPVIFLGADFTHPPAGDKTKPSIAAVVGSMDAHPSRYAATVSVQPHRQETIQDLAAMVKELLIQFYKSTRFKPTRIIYYRDGVSEGQFLNVLNHELKAIREACIKLEMSYQPGITFVVVQKRHHTRLFCSDKKDQMGRSGNIPAGTTVDQIITHPTEFDFYLCSHAGIQGTSRPSHYHVLWDDNRFSADEIQTLTYQLCHTYVRCTRSVSIPAPAYYAHLVAFRARYHLVEKELDSGEGSQKSGNSDERNPTAMMRAVTVHSETLKVMYFA 2784
            + F+PP+RP +G+DGR I L+ANHFEI MPKGFLHHYD++I PEKCPRRVNR+II+ MVN+MHYQKYFYNQKPVFDGRRNMYTR+PL I KEK+ELEV LPGEGKDRVF+V +KHVSEVSLFALEEAL G  + IP + V +LDVIMRHLPSM+YTPVGRSFF N   Y+NPLGGGREVWFGFHQSVRPSQW+MMLNIDVSATAFYK QSVI+FM EVL+I DK + +R LTDSQRVKFTKEIKGLKVEI HCG ++RKYRVCNVTRR A +Q+FPLQ E G T+ECTV KYFQ+RY ++L++PHLPCLQVGQEQKHTYLPLEVCN+V+GQRCIKKLTDMQTSTMIKATARSAPDREKEINNLV+R+NFNADPHLQ+FG++VNTRMA+IQGRVIPAPKIQYGGRTKAQA+PQ GVWDMRGKQFFSGIEIKVWAIACFAPQR VREDSLR FT QLQKISNDAGMPI+ QPCFCKYATGQDQVEPMFRYLKN+ +GLQLIVVVLPGKTPVYAEVKRVGDI+FGLATQCVQ+KNVNK SPQTLSNLCLKINVKLGGINSI+VPSVRPAVF+EPVIFLGAD THPPAGDKTKPSIAAVV SMDAHPSRY+ATV VQPHRQE IQDL  MVK+LL+QFY++TRFKPTRIIYYRDGVSEGQFLNVLNHEL+AIREAC+KLE+ YQPGITF+VVQKRHHTRLFC+DKKDQMG+SGNIPAGTTVDQ+ITHPTEFDFYLCSHAGIQGTSRPSHYHVLWDDNRFSAD+IQ LTYQLCHTYVRCTRSVSIPAPAYYAHLVAFRARYHLVEKE+DSGEGSQKSGNSDER PTAMMRAVTVH ETL+VMYFA
Sbjct:  174 IQFEPPARPGRGSDGRAISLRANHFEIRMPKGFLHHYDVSIVPEKCPRRVNREIIETMVNSMHYQKYFYNQKPVFDGRRNMYTRDPLPISKEKVELEVTLPGEGKDRVFRVAIKHVSEVSLFALEEALGGHIRHIPNDAVVSLDVIMRHLPSMSYTPVGRSFFQNPDGYENPLGGGREVWFGFHQSVRPSQWRMMLNIDVSATAFYKAQSVIDFMCEVLDISDKSEQRRALTDSQRVKFTKEIKGLKVEITHCGTMRRKYRVCNVTRRPAHTQSFPLQLETGATMECTVAKYFQERYNIRLEYPHLPCLQVGQEQKHTYLPLEVCNMVAGQRCIKKLTDMQTSTMIKATARSAPDREKEINNLVKRANFNADPHLQMFGINVNTRMAEIQGRVIPAPKIQYGGRTKAQASPQLGVWDMRGKQFFSGIEIKVWAIACFAPQRIVREDSLRLFTLQLQKISNDAGMPILAQPCFCKYATGQDQVEPMFRYLKNTHAGLQLIVVVLPGKTPVYAEVKRVGDIMFGLATQCVQSKNVNKTSPQTLSNLCLKINVKLGGINSIIVPSVRPAVFREPVIFLGADVTHPPAGDKTKPSIAAVVASMDAHPSRYSATVRVQPHRQEIIQDLYPMVKDLLLQFYRATRFKPTRIIYYRDGVSEGQFLNVLNHELRAIREACVKLELGYQPGITFIVVQKRHHTRLFCADKKDQMGKSGNIPAGTTVDQVITHPTEFDFYLCSHAGIQGTSRPSHYHVLWDDNRFSADDIQNLTYQLCHTYVRCTRSVSIPAPAYYAHLVAFRARYHLVEKEIDSGEGSQKSGNSDERTPTAMMRAVTVHPETLRVMYFA 1013

[Close]

BLAST of AGO-2 vs. TrEMBL
Match: A0A3R7D5K5 (Protein argonaute-2 OS=Clonorchis sinensis OX=79923 GN=AGO2 PE=3 SV=1)

HSP 1 Score: 1544.64 bits (3998), Expect = 0.000e+0
Identity = 720/840 (85.71%), Postives = 786/840 (93.57%), Query Frame = 1

Query:  271 VYFQPPSRPDQGTDGRTIQLKANHFEIVMPKGFLHHYDITITPEKCPRRVNRDIIQAMVNNMHYQKYFYNQKPVFDGRRNMYTREPLSIGKEKLELEVILPGEGKDRVFKVCLKHVSEVSLFALEEALQGRRQTIPAETVTALDVIMRHLPSMTYTPVGRSFFHNTGDYDNPLGGGREVWFGFHQSVRPSQWKMMLNIDVSATAFYKEQSVINFMFEVLEI-DK-DLKRPLTDSQRVKFTKEIKGLKVEINHCGPIKRKYRVCNVTRRSAQSQTFPLQSEQGQTIECTVTKYFQDRYGMKLQHPHLPCLQVGQEQKHTYLPLEVCNIVSGQRCIKKLTDMQTSTMIKATARSAPDREKEINNLVRRSNFNADPHLQIFGVSVNTRMADIQGRVIPAPKIQYGGRTKAQATPQQGVWDMRGKQFFSGIEIKVWAIACFAPQRTVREDSLRTFTQQLQKISNDAGMPIVGQPCFCKYATGQDQVEPMFRYLKNSFSGLQLIVVVLPGKTPVYAEVKRVGDIIFGLATQCVQAKNVNKPSPQTLSNLCLKINVKLGGINSILVPSVRPAVFKEPVIFLGADFTHPPAGDKTKPSIAAVVGSMDAHPSRYAATVSVQPHRQETIQDLAAMVKELLIQFYKSTRFKPTRIIYYRDGVSEGQFLNVLNHELKAIREACIKLEMSYQPGITFVVVQKRHHTRLFCSDKKDQMGRSGNIPAGTTVDQIITHPTEFDFYLCSHAGIQGTSRPSHYHVLWDDNRFSADEIQTLTYQLCHTYVRCTRSVSIPAPAYYAHLVAFRARYHLVEKELDSGEGSQKSGNSDERNPTAMMRAVTVHSETLKVMYFA 2784
            + F+PP+RP +G+DGR I L+ANHFEI MPKGFLHHYD++I PEKCPRRVNR+II+ MVN+MHYQKYFYNQKPVFDGRRNMYTR+PL I KEK+ELEV LPGEGKDRVF+V +KHVSEVSLFALEEAL G  + IP + V +LDVIMRHLPSM+YTPVGRSFF N   Y+NPLGGGREVWFGFHQSVRPSQW+MMLNIDVSATAFYK QSVI+FM EVL+I DK + +R LTDSQRVKFTKEIKGLKVEI HCG ++RKYRVCNVTRR A +Q+FPLQ E G T+ECTV KYFQ+RY ++L++PHLPCLQVGQEQKHTYLPLEVCN+V+GQRCIKKLTDMQTSTMIKATARSAPDREKEINNLV+R+NFNADPHLQ+FG++VNTRMA+IQGRVIPAPKIQYGGRTKAQA+PQ GVWDMRGKQFFSGIEIKVWAIACFAPQR VREDSLR FT QLQKISNDAGMPI+ QPCFCKYATGQDQVEPMFRYLKN+ +GLQLIVVVLPGKTPVYAEVKRVGDI+FGLATQCVQ+KNVNK SPQTLSNLCLKINVKLGGINSI+VPSVRPAVF+EPVIFLGAD THPPAGDKTKPSIAAVV SMDAHPSRY+ATV VQPHRQE IQDL  MVK+LL+QFY++TRFKPTRIIYYRDGVSEGQFLNVLNHEL+AIREAC+KLE+ YQPGITF+VVQKRHHTRLFC+DKKDQMG+SGNIPAGTTVDQ+ITHPTEFDFYLCSHAGIQGTSRPSHYHVLWDDNRFSAD+IQ LTYQLCHTYVRCTRSVSIPAPAYYAHLVAFRARYHLVEKE+DSGEGSQKSGNSDER PTAMMRAVTVH ETL+VMYFA
Sbjct:  175 IQFEPPARPGRGSDGRAISLRANHFEIRMPKGFLHHYDVSIVPEKCPRRVNREIIETMVNSMHYQKYFYNQKPVFDGRRNMYTRDPLPISKEKVELEVTLPGEGKDRVFRVAIKHVSEVSLFALEEALGGHIRHIPNDAVVSLDVIMRHLPSMSYTPVGRSFFQNPDGYENPLGGGREVWFGFHQSVRPSQWRMMLNIDVSATAFYKAQSVIDFMCEVLDISDKSEQRRALTDSQRVKFTKEIKGLKVEITHCGTMRRKYRVCNVTRRPAHTQSFPLQLETGATMECTVAKYFQERYNIRLEYPHLPCLQVGQEQKHTYLPLEVCNMVAGQRCIKKLTDMQTSTMIKATARSAPDREKEINNLVKRANFNADPHLQMFGINVNTRMAEIQGRVIPAPKIQYGGRTKAQASPQLGVWDMRGKQFFSGIEIKVWAIACFAPQRIVREDSLRLFTLQLQKISNDAGMPILAQPCFCKYATGQDQVEPMFRYLKNTHAGLQLIVVVLPGKTPVYAEVKRVGDIMFGLATQCVQSKNVNKTSPQTLSNLCLKINVKLGGINSIIVPSVRPAVFREPVIFLGADVTHPPAGDKTKPSIAAVVASMDAHPSRYSATVRVQPHRQEIIQDLYPMVKDLLLQFYRATRFKPTRIIYYRDGVSEGQFLNVLNHELRAIREACVKLELGYQPGITFIVVQKRHHTRLFCADKKDQMGKSGNIPAGTTVDQVITHPTEFDFYLCSHAGIQGTSRPSHYHVLWDDNRFSADDIQNLTYQLCHTYVRCTRSVSIPAPAYYAHLVAFRARYHLVEKEIDSGEGSQKSGNSDERTPTAMMRAVTVHPETLRVMYFA 1014

[Close]

BLAST of AGO-2 vs. Ensembl Cavefish
Match: ago2 (argonaute RISC catalytic component 2 [Source:NCBI gene;Acc:103030212])

HSP 1 Score: 1304.66 bits (3375), Expect = 0.000e+0
Identity = 633/892 (70.96%), Postives = 721/892 (80.83%), Query Frame = 1

Query:  115 MNPLGAPGQPPNTSVPAIIGSTQLSSNISSGPSPPQLPTXXXXXXXXXXXXXVYFQPPSRPDQGTDGRTIQLKANHFEIVMPKGFLHHYDITITPEKCPRRVNRDIIQAMVNNMHYQKYFYNQKPVFDGRRNMYTREPLSIGKEKLELEVILPGEGKDRVFKVCLKHVSEVSLFALEEALQGRRQTIPAETVTALDVIMRHLPSMTYTPVGRSFFHNTGDYDNPLGGGREVWFGFHQSVRPSQWKMMLNIDVSATAFYKEQSVINFMFEVLEID--KDLKRPLTDSQRVKFTKEIKGLKVEINHCGPIKRKYRVCNVTRRSAQSQTFPLQSEQGQTIECTVTKYFQDRYGMKLQHPHLPCLQVGQEQKHTYLPLEVCNIVSGQRCIKKLTDMQTSTMIKATARSAPDREKEINNLVRRSNFNADPHLQIFGVSVNTRMADIQGRVIPAPKIQYGGRTKAQATPQQGVWDMRGKQFFSGIEIKVWAIACFAPQRTVREDSLRTFTQQLQKISNDAGMPIVGQPCFCKYATGQDQVEPMFRYLKNSFSGLQLIVVVLPGKTPVYAEVKRVGDIIFGLATQCVQAKNVNKPSPQTLSNLCLKINVKLGGINSILVPSVRPAVFKEPVIFLGADFTHPPAGDKTKPSIAAVVGSMDAHPSRYAATVSVQPHRQETIQDLAAMVKELLIQFYKSTRFKPTRIIYYRDGVSEGQFLNVLNHELKAIREACIKLEMSYQPGITFVVVQKRHHTRLFCSDKKDQMGRSGNIPAGTTVDQIITHPTEFDFYLCSHAGIQGTSRPSHYHVLWDDNRFSADEIQTLTYQLCHTYVRCTRSVSIPAPAYYAHLVAFRARYHLVEKELDSGEGSQKSGNSDERNPTAMMRAVTVHSETLKVMYFA 2784
            M P GA G           G T   S  S+ PSPP              +    F+PP RPD GT GRTI+L+AN FE+ +PK  ++HYDI I PEKCPRRVNR+I++ MV +   Q  F ++KPV+DGR+N+YT  PL IG++K+ELEV +PGEGKDR FKV +K VS VSL AL EAL GR  +IP ET+ ALDV+MRHLPSM YTPVGRSFF  +    NPLGGGREVWFGFHQSVRPS WKMMLNIDVSATAFYK Q VI FM EVL+    ++ ++PLTDSQRVKFTKEIKGLKVEI HCG +KRKYRVCNVTRR A  QTFPLQ E GQTIECTV +YF+D+Y + L++PHLPCLQVGQEQKHTYLPLEVCNIV+GQRCIKKLTD QTSTMI+ATARSAPDR+ EI+ L+R +NFN DP+++ FGV V   M ++ GRV+ AP I YGGR KA ATP QGVWDMR KQF +GIEIKVWAIACFAPQR   E  L+ FT QL+KIS DAGMPI GQPCFCKYA G D VEPMF++LK ++ GLQL+VV+LPGKTPVYAEVKRVGD + G+ATQCVQ KNV K +PQTLSNLCLKINVKLGG+N+IL+P  RP VF++PVIFLGAD THPPAGD  KPSIAAVVGSMDAHPSRY ATV VQ HRQ+ IQDLAAMV+ELLIQFYKSTRFKPTRIIYYRDG+SEGQF  VL HEL AIREACIKLE  YQPGITFVVVQKRHHTRLFC D+ +++G+SGNIPAGTTVD  ITHP+EFDFYLCSHAGIQGTSRPSHYHVLWDDN F++DE+Q LTYQLCHTYVRCTRSVSIPAPAYYAHLVAFRARYHLV+KE DS EGS  SG S+ R+  A+ +AV +H +TL+ MYFA
Sbjct:    1 MYPSGAAGVAEMCE-----GLTSSRSVDSAPPSPP--------------SHEYVFKPPQRPDFGTMGRTIKLQANFFEMEIPKLEMYHYDIDIKPEKCPRRVNREIVEHMVQHFKTQ-IFGDRKPVYDGRKNLYTAMPLPIGRDKVELEVTIPGEGKDRSFKVAIKWVSCVSLQALHEALSGRLPSIPFETIQALDVVMRHLPSMRYTPVGRSFFTPSEGCSNPLGGGREVWFGFHQSVRPSLWKMMLNIDVSATAFYKAQPVIEFMCEVLDFKSIEEQQKPLTDSQRVKFTKEIKGLKVEITHCGQMKRKYRVCNVTRRPASHQTFPLQQENGQTIECTVAQYFKDKYKLVLRYPHLPCLQVGQEQKHTYLPLEVCNIVAGQRCIKKLTDNQTSTMIRATARSAPDRQDEISKLMRSANFNTDPYVREFGVMVRDEMTEVNGRVLQAPSILYGGRNKAIATPIQGVWDMRNKQFHTGIEIKVWAIACFAPQRQCTELLLKAFTDQLRKISRDAGMPIQGQPCFCKYAQGADSVEPMFKHLKYTYQGLQLVVVILPGKTPVYAEVKRVGDTVLGMATQCVQVKNVQKTTPQTLSNLCLKINVKLGGVNNILLPQGRPLVFQQPVIFLGADVTHPPAGDGKKPSIAAVVGSMDAHPSRYCATVRVQQHRQDIIQDLAAMVRELLIQFYKSTRFKPTRIIYYRDGISEGQFNQVLQHELLAIREACIKLEKDYQPGITFVVVQKRHHTRLFCMDRNERVGKSGNIPAGTTVDTKITHPSEFDFYLCSHAGIQGTSRPSHYHVLWDDNHFTSDELQVLTYQLCHTYVRCTRSVSIPAPAYYAHLVAFRARYHLVDKEHDSAEGSHTSGQSNGRDQQALAKAVQIHQDTLRTMYFA 872

[Close]

BLAST of AGO-2 vs. Ensembl Cavefish
Match: ago2 (argonaute RISC catalytic component 2 [Source:NCBI gene;Acc:103030212])

HSP 1 Score: 1302.35 bits (3369), Expect = 0.000e+0
Identity = 620/838 (73.99%), Postives = 706/838 (84.25%), Query Frame = 1

Query:  277 FQPPSRPDQGTDGRTIQLKANHFEIVMPKGFLHHYDITITPEKCPRRVNRDIIQAMVNNMHYQKYFYNQKPVFDGRRNMYTREPLSIGKEKLELEVILPGEGKDRVFKVCLKHVSEVSLFALEEALQGRRQTIPAETVTALDVIMRHLPSMTYTPVGRSFFHNTGDYDNPLGGGREVWFGFHQSVRPSQWKMMLNIDVSATAFYKEQSVINFMFEVLEID--KDLKRPLTDSQRVKFTKEIKGLKVEINHCGPIKRKYRVCNVTRRSAQSQTFPLQSEQGQTIECTVTKYFQDRYGMKLQHPHLPCLQVGQEQKHTYLPLEVCNIVSGQRCIKKLTDMQTSTMIKATARSAPDREKEINNLVRRSNFNADPHLQIFGVSVNTRMADIQGRVIPAPKIQYGGRTKAQATPQQGVWDMRGKQFFSGIEIKVWAIACFAPQRTVREDSLRTFTQQLQKISNDAGMPIVGQPCFCKYATGQDQVEPMFRYLKNSFSGLQLIVVVLPGKTPVYAEVKRVGDIIFGLATQCVQAKNVNKPSPQTLSNLCLKINVKLGGINSILVPSVRPAVFKEPVIFLGADFTHPPAGDKTKPSIAAVVGSMDAHPSRYAATVSVQPHRQETIQDLAAMVKELLIQFYKSTRFKPTRIIYYRDGVSEGQFLNVLNHELKAIREACIKLEMSYQPGITFVVVQKRHHTRLFCSDKKDQMGRSGNIPAGTTVDQIITHPTEFDFYLCSHAGIQGTSRPSHYHVLWDDNRFSADEIQTLTYQLCHTYVRCTRSVSIPAPAYYAHLVAFRARYHLVEKELDSGEGSQKSGNSDERNPTAMMRAVTVHSETLKVMYFA 2784
            F+PP RPD GT GRTI+L+AN FE+ +PK  ++HYDI I PEKCPRRVNR+I++ MV +   Q  F ++KPV+DGR+N+YT  PL IG++K+ELEV +PGEGKDR FKV +K VS VSL AL EAL GR  +IP ET+ ALDV+MRHLPSM YTPVGRSFF  +    NPLGGGREVWFGFHQSVRPS WKMMLNIDVSATAFYK Q VI FM EVL+    ++ ++PLTDSQRVKFTKEIKGLKVEI HCG +KRKYRVCNVTRR A  QTFPLQ E GQTIECTV +YF+D+Y + L++PHLPCLQVGQEQKHTYLPLEVCNIV+GQRCIKKLTD QTSTMI+ATARSAPDR+ EI+ L+R +NFN DP+++ FGV V   M ++ GRV+ AP I YGGR KA ATP QGVWDMR KQF +GIEIKVWAIACFAPQR   E  L+ FT QL+KIS DAGMPI GQPCFCKYA G D VEPMF++LK ++ GLQL+VV+LPGKTPVYAEVKRVGD + G+ATQCVQ KNV K +PQTLSNLCLKINVKLGG+N+IL+P  RP VF++PVIFLGAD THPPAGD  KPSIAAVVGSMDAHPSRY ATV VQ HRQ+ IQDLAAMV+ELLIQFYKSTRFKPTRIIYYRDG+SEGQF  VL HEL AIREACIKLE  YQPGITFVVVQKRHHTRLFC D+ +++G+SGNIPAGTTVD  ITHP+EFDFYLCSHAGIQGTSRPSHYHVLWDDN F++DE+Q LTYQLCHTYVRCTRSVSIPAPAYYAHLVAFRARYHLV+KE DS EGS  SG S+ R+  A+ +AV +H +TL+ MYFA
Sbjct:   20 FKPPQRPDFGTMGRTIKLQANFFEMEIPKLEMYHYDIDIKPEKCPRRVNREIVEHMVQHFKTQ-IFGDRKPVYDGRKNLYTAMPLPIGRDKVELEVTIPGEGKDRSFKVAIKWVSCVSLQALHEALSGRLPSIPFETIQALDVVMRHLPSMRYTPVGRSFFTPSEGCSNPLGGGREVWFGFHQSVRPSLWKMMLNIDVSATAFYKAQPVIEFMCEVLDFKSIEEQQKPLTDSQRVKFTKEIKGLKVEITHCGQMKRKYRVCNVTRRPASHQTFPLQQENGQTIECTVAQYFKDKYKLVLRYPHLPCLQVGQEQKHTYLPLEVCNIVAGQRCIKKLTDNQTSTMIRATARSAPDRQDEISKLMRSANFNTDPYVREFGVMVRDEMTEVNGRVLQAPSILYGGRNKAIATPIQGVWDMRNKQFHTGIEIKVWAIACFAPQRQCTELLLKAFTDQLRKISRDAGMPIQGQPCFCKYAQGADSVEPMFKHLKYTYQGLQLVVVILPGKTPVYAEVKRVGDTVLGMATQCVQVKNVQKTTPQTLSNLCLKINVKLGGVNNILLPQGRPLVFQQPVIFLGADVTHPPAGDGKKPSIAAVVGSMDAHPSRYCATVRVQQHRQDIIQDLAAMVRELLIQFYKSTRFKPTRIIYYRDGISEGQFNQVLQHELLAIREACIKLEKDYQPGITFVVVQKRHHTRLFCMDRNERVGKSGNIPAGTTVDTKITHPSEFDFYLCSHAGIQGTSRPSHYHVLWDDNHFTSDELQVLTYQLCHTYVRCTRSVSIPAPAYYAHLVAFRARYHLVDKEHDSAEGSHTSGQSNGRDQQALAKAVQIHQDTLRTMYFA 856

[Close]

BLAST of AGO-2 vs. Ensembl Cavefish
Match: ago4 (protein argonaute-4 [Source:NCBI gene;Acc:103043810])

HSP 1 Score: 1228 bits (3176), Expect = 0.000e+0
Identity = 593/861 (68.87%), Postives = 690/861 (80.14%), Query Frame = 1

Query:  277 FQPPSRPDQGTDGRTIQLKANHFEIVMPKGFLHHYDITITPEKCPRRVNRDIIQAMVNNMHYQKYFYNQKPVFDGRRNMYTREPLSIGKEKLELEVILPGEGKDRVFKVCLKHVSEVSLFALEEALQGRRQTIPAETVTALDVIMRHLPSMTYTPVGRSFFHNTGDYDNPLGGGREVWFGFHQSVRPSQWKMMLNIDVSATAFYKEQSVINFMFEVLEIDK--DLKRPLTDSQRVKFTKEIKGLKVEINHCGPIKRKYRVCNVTRRSAQSQTFPLQSEQGQTIECTVTKYFQDRYGMKLQHPHLPCLQVGQEQKHTYLPLEVCNIVSGQRCIKKLTDMQTSTMIKATARSAPDREKEINNLVRRSNF--NADPHLQIFGVSVNTRMADIQGRVIPAPKIQYGGRT-----------KAQATPQQGVWDMRGKQFFSGIEIKVWAIACFAPQRTVREDSLRTFTQQLQKISNDAGMPIVGQPCFCKYATGQDQVEPMFRYLKNSFSGLQLIVVVLPGKTPVYAEVKRVGDIIFGLATQCVQAKNVNKPSPQTLSNLCLKINVKLGGINSILVPSVRPAVFKEPVIFLGADFTHPPAGDKTKPSIAAVVGSMDAHPSRYAATVSVQPHRQ----------ETIQDLAAMVKELLIQFYKSTRFKPTRIIYYRDGVSEGQFLNVLNHELKAIREACIKLEMSYQPGITFVVVQKRHHTRLFCSDKKDQMGRSGNIPAGTTVDQIITHPTEFDFYLCSHAGIQGTSRPSHYHVLWDDNRFSADEIQTLTYQLCHTYVRCTRSVSIPAPAYYAHLVAFRARYHLVEKELDSGEGSQKSGNSDERNPTAMMRAVTVHSETLKVMYFA 2784
            FQPP RP  GT G+ I+L ANHF++ +PK  ++HYDI I PEK PRRVNR+++  MV +   Q  F +++P +DG+RNMYT  PL IG+++++LEV LPGEGKD+ FKV L+ VS VSL  L EAL G    +P ++V ALDVI RHLPSM YTPVGRSFF     Y +PLGGGREVWFGFHQSVRP+ W MMLNIDVSATAFY+ Q VI FM EVL+I    +  +PLTDSQRVKFTKEI+GLKVE+ HCG +KRKYRVCNVTRR A  QTFPLQ E GQ +ECTV +YF+ +Y ++L++PHLPCLQVGQEQKHTYLPLEVCNIV+GQRCIKKLTD QTSTMIKATARSAPDR++EI+ LV+ ++     DP+L+ FG+ V+  M ++ GRV+PAP +QYGGR            K  ATP QGVWDMRGKQF++GIEIKVWA+ACFAPQ+  RED L++FT QL+KIS DAGMPI GQPCFCKYA G D VEPMF++LK S+ GLQLIVV+LPGKTPVYAEVKRVGD + G+ATQCVQ KNV K SPQTLSNLCLKIN KLGGIN++LVP  RP+VF++PVIFLGAD THPPAGD  KPSIAAVVGSMD HPSRY ATV VQ  RQ          E IQDL  MV+ELLIQFYKSTRFKPTRIIYYR GVSEGQ   V   EL AIR+ACI LE  Y+PGIT++VVQKRHHTRLFCSDK +++G+SGN+PAGTTVD  ITHP+EFDFYLCSHAGIQGTSRPSHYHVLWDDN F+ADE+Q LTYQLCHTYVRCTRSVSIPAPAYYA LVAFRARYHLV+K+ DS EGS  SG S+ R+P A+ +AV +H +T   MYFA
Sbjct:   15 FQPPRRPGLGTVGKPIRLLANHFQVQIPKIDVYHYDIEIKPEKRPRRVNREVVDTMVRHFKMQ-IFGDRQPGYDGKRNMYTAHPLPIGRDRVDLEVTLPGEGKDQTFKVSLQWVSVVSLQMLLEALSGHLNEVPEDSVQALDVITRHLPSMRYTPVGRSFFSPPEGYYHPLGGGREVWFGFHQSVRPAMWNMMLNIDVSATAFYRAQPVIEFMCEVLDIQNINEQTKPLTDSQRVKFTKEIRGLKVEVTHCGQMKRKYRVCNVTRRPASHQTFPLQLENGQAMECTVAQYFKQKYSLQLKYPHLPCLQVGQEQKHTYLPLEVCNIVAGQRCIKKLTDNQTSTMIKATARSAPDRQEEISRLVKSNSMVGGPDPYLKEFGIVVHNDMTEVTGRVLPAPMLQYGGRVSTDTGRDCGRNKTVATPNQGVWDMRGKQFYAGIEIKVWAVACFAPQKQCREDLLKSFTDQLRKISKDAGMPIQGQPCFCKYAQGADSVEPMFKHLKMSYVGLQLIVVILPGKTPVYAEVKRVGDTLLGMATQCVQVKNVVKTSPQTLSNLCLKINAKLGGINNVLVPHQRPSVFQQPVIFLGADVTHPPAGDGKKPSIAAVVGSMDGHPSRYCATVRVQTSRQDLSQEQLYSQEVIQDLTNMVRELLIQFYKSTRFKPTRIIYYRGGVSEGQMKQVAWPELIAIRKACISLEEDYRPGITYIVVQKRHHTRLFCSDKAERVGKSGNVPAGTTVDSTITHPSEFDFYLCSHAGIQGTSRPSHYHVLWDDNCFTADELQLLTYQLCHTYVRCTRSVSIPAPAYYARLVAFRARYHLVDKDHDSAEGSHVSGQSNGRDPQALAKAVQIHYDTQHTMYFA 874

[Close]

BLAST of AGO-2 vs. Ensembl Cavefish
Match: ago3b (argonaute RISC catalytic component 3b [Source:NCBI gene;Acc:568159])

HSP 1 Score: 1145.95 bits (2963), Expect = 0.000e+0
Identity = 553/782 (70.72%), Postives = 636/782 (81.33%), Query Frame = 1

Query:  472 FYNQKPVFDGRRNMYTREPLSIGKEKLELEVILPGEG-KDRVFKVCLKHVSEVSLFALEEALQGRRQTIPAET--------VTALDVIMRHLPSMTYTPVGRSFFHNTGDYDNPLGGGREVWFGFHQSVRPSQWKMMLNIDVSATAFYKEQSVINFMFEVLEIDK--DLKRPLTDSQRVKFTKEIKGLKVEINHCGPIKRKYRVCNVTRRSAQSQTFPLQSEQGQTIECTVTKYFQDRYGMKLQHPHLPCLQVGQEQKHTYLPLEVCNIVSGQRCIKKLTDMQTSTMIKATARSAPDREKEINNLVRRSNFNADPHLQIFGVSVNTRMADIQGRVIPAPKIQYGGRTKAQATPQQGVWDMRGKQFFSGIEIKVWAIACFAPQRTVREDSLRTFTQQLQKISNDAGMPIVGQPCFCKYATGQDQVEPMFRYLKNSFSGLQLIVVVLPGKTPVYAEVKRVGDIIFGLATQCVQAKNVNKPSPQTLSNLCLKINVKLGGINSILVPSVRPAVFKEPVIFLGADFTHPPAGDKTKPSIAAVVGSMDAHPSRYAATVSVQPHRQETIQDLAAMVKELLIQFYKSTRFKPTRIIYYRDGVSEGQFLNVLNHELKAIREACIKLEMSYQPGITFVVVQKRHHTRLFCSDKKDQMGRSGNIPAGTTVDQIITHPTEFDFYLCSHAGIQGTSRPSHYHVLWDDNRFSADEIQTLTYQLCHTYVRCTRSVSIPAPAYYAHLVAFRARYHLVEKELDSGEGSQKSGNSDERNPTAMMRAVTVHSETLKVMYFA 2784
            F ++KPV+DG+R++YT  PL +    ++L+V LPGEG KDR FKV +K VS VS   L E L GR    P +         V A+DV++RHLPSM YTPVGRSFF +   YD+PLGGGREVWFGFHQSVRP+ WKMMLNIDVSATAFYK Q VI FM EVL+I    +  RPLTDS RVKFTKEIKGLKVE+ HCG ++RKYRVCNVTRR A  QTFPLQ E GQT+E TV +YF+++Y ++L++PHLPCLQVGQEQKHTYLPLEVCNIV+GQRCIKKLTD QTSTMIKATARSAPDR++EI+ LVR +N+ ADP +Q F   V   MA++ GRV+PAP +QYGGR +  ATP  GVWDMRGKQF +G+EIK+WAIACFA QR  RE+ L++FT QL+KIS DAGMPI GQPCFCKYA G D VEPMFR+LKN+++GLQLI+V+LPGKTPVYAEVKRVGD + G+ATQCVQ KNV K SPQTLSNLCLKIN              R A+F +PVIFLGAD THPPAGD  KPSIAAVVGSMDAHPSRY ATV VQ  RQE IQDLA+MV+ELLIQFYKSTR+KPTR+I+YRDGVSEGQF  VL +EL AIREACI LE  YQPGIT++VVQKRHHTRLFC+D+ +++GRSGNIPAGTTVD  ITHP EFDFYLCSHAGIQGTSRPSHYHVLWDDN F+ADE Q LTYQLCHTYVRCTRSVSIPAPAYYAHLVAFRARYHLV+KE DS EGS  SG S+ R+P A+ +AV +H +TL+ MYFA
Sbjct:   10 FGDRKPVYDGKRSLYTAHPLPVATGGVDLDVTLPGEGGKDRPFKVSIKFVSLVSWHMLHEVLTGRTMPEPIDLDKPISTNPVHAVDVVLRHLPSMRYTPVGRSFFSSPEGYDHPLGGGREVWFGFHQSVRPAMWKMMLNIDVSATAFYKAQQVIQFMCEVLDIHNIDEQPRPLTDSHRVKFTKEIKGLKVEVTHCGTMRRKYRVCNVTRRPASHQTFPLQLENGQTVERTVAQYFREKYNLQLKYPHLPCLQVGQEQKHTYLPLEVCNIVAGQRCIKKLTDNQTSTMIKATARSAPDRQEEISRLVRSANYEADPFVQEFQFRVRDEMAEVTGRVLPAPMLQYGGRNRTVATPSHGVWDMRGKQFHTGVEIKMWAIACFATQRQCREEILKSFTDQLRKISKDAGMPIQGQPCFCKYAQGADSVEPMFRHLKNTYAGLQLIIVILPGKTPVYAEVKRVGDTLLGMATQCVQVKNVVKTSPQTLSNLCLKIN--------------RCALF-QPVIFLGADVTHPPAGDGKKPSIAAVVGSMDAHPSRYCATVRVQRPRQEIIQDLASMVRELLIQFYKSTRYKPTRLIFYRDGVSEGQFRQVLYYELLAIREACISLEREYQPGITYIVVQKRHHTRLFCADRNERVGRSGNIPAGTTVDTDITHPYEFDFYLCSHAGIQGTSRPSHYHVLWDDNCFTADEFQLLTYQLCHTYVRCTRSVSIPAPAYYAHLVAFRARYHLVDKEHDSAEGSHVSGQSNGRDPQALAKAVQIHHDTLRTMYFA 776

[Close]

BLAST of AGO-2 vs. Ensembl Cavefish
Match: ago3a (argonaute RISC catalytic component 3a [Source:ZFIN;Acc:ZDB-GENE-051107-16])

HSP 1 Score: 1142.49 bits (2954), Expect = 0.000e+0
Identity = 554/782 (70.84%), Postives = 631/782 (80.69%), Query Frame = 1

Query:  472 FYNQKPVFDGRRNMYTREPLSIGKEKLELEVILPGEG-KDRVFKVCLKHVSEVSLFALEEALQGRRQTIPAET--------VTALDVIMRHLPSMTYTPVGRSFFHNTGDYDNPLGGGREVWFGFHQSVRPSQWKMMLNIDVSATAFYKEQSVINFMFEVLEIDK--DLKRPLTDSQRVKFTKEIKGLKVEINHCGPIKRKYRVCNVTRRSAQSQTFPLQSEQGQTIECTVTKYFQDRYGMKLQHPHLPCLQVGQEQKHTYLPLEVCNIVSGQRCIKKLTDMQTSTMIKATARSAPDREKEINNLVRRSNFNADPHLQIFGVSVNTRMADIQGRVIPAPKIQYGGRTKAQATPQQGVWDMRGKQFFSGIEIKVWAIACFAPQRTVREDSLRTFTQQLQKISNDAGMPIVGQPCFCKYATGQDQVEPMFRYLKNSFSGLQLIVVVLPGKTPVYAEVKRVGDIIFGLATQCVQAKNVNKPSPQTLSNLCLKINVKLGGINSILVPSVRPAVFKEPVIFLGADFTHPPAGDKTKPSIAAVVGSMDAHPSRYAATVSVQPHRQETIQDLAAMVKELLIQFYKSTRFKPTRIIYYRDGVSEGQFLNVLNHELKAIREACIKLEMSYQPGITFVVVQKRHHTRLFCSDKKDQMGRSGNIPAGTTVDQIITHPTEFDFYLCSHAGIQGTSRPSHYHVLWDDNRFSADEIQTLTYQLCHTYVRCTRSVSIPAPAYYAHLVAFRARYHLVEKELDSGEGSQKSGNSDERNPTAMMRAVTVHSETLKVMYFA 2784
            F +++PV+DG++++YT  PL +    ++L+V LPGEG KDR FKV +K VS VS   L E L GR    P E         V A+DV++RHLPSM YTPVGRSFF     YD+PLGGGREVWFGFHQSVRP+ WKMMLNIDVSATAFYK Q VI FM EVL+I    +  RPLTDS RVKFTKEIKGLKVE+ HCG ++RKYRVCNVTRR A  QTFPLQ E GQT+E TV +YF+++Y ++L++PHLPCLQVGQEQKHTYLPLEVCNIV+GQRCIKKLTD QTSTMIKATARSAPDR++EI+ LVR +N+ ADP +Q F   V   MA + GRV+PAP +QYGGR +  ATP  GVWDMRGKQF +G+EIK+WAIACFA QR  RE+ L+ FT QL+KIS DAGMPI GQPCFCKYA G D VEPMFR+LKN+++GLQLI+V+LPGKTPVYAEVKRVGD + G+ATQCVQ KNV K SPQTLSNLCLKINVKLGGIN+ILVP  RP+VF++PVIFLGAD THPPAGD  KPSIAAVVGSMDAHPSRY ATV VQ  RQE IQDLA+MV+ELLIQFYKSTR+KPTRII+YRDGVSEGQF  VL +EL AIREACI LE  YQPGIT++VV                 GRSGNIPAGTTVD  ITHP EFDFYLCSHAGIQGTSRPSHYHVLWDDN F+ADE Q LTYQLCHTYVRCTRSVSIPAPAYYAHLVAFRARYHLV+KE DS EGS  SG S+ R+P A+ +AV +H +TL+ MYFA
Sbjct:   10 FGDRRPVYDGKKSLYTANPLPVAPAGVDLDVTLPGEGGKDRPFKVTIKFVSLVSWHLLHEVLTGRSMPEPLELDKPISTNPVHAVDVVLRHLPSMKYTPVGRSFFSAPEGYDHPLGGGREVWFGFHQSVRPAMWKMMLNIDVSATAFYKAQPVIQFMCEVLDIHNIDEQPRPLTDSHRVKFTKEIKGLKVEVTHCGTMRRKYRVCNVTRRPASHQTFPLQLENGQTVERTVAQYFREKYNLQLKYPHLPCLQVGQEQKHTYLPLEVCNIVAGQRCIKKLTDNQTSTMIKATARSAPDRQEEISRLVRSANYEADPFVQEFQFRVRDEMAHVTGRVLPAPMLQYGGRNRTVATPSHGVWDMRGKQFHTGVEIKMWAIACFATQRQCREEILKGFTDQLRKISKDAGMPIQGQPCFCKYAQGADSVEPMFRHLKNTYAGLQLIIVILPGKTPVYAEVKRVGDTLLGMATQCVQVKNVVKTSPQTLSNLCLKINVKLGGINNILVPHQRPSVFQQPVIFLGADVTHPPAGDGKKPSIAAVVGSMDAHPSRYCATVRVQRPRQEVIQDLASMVRELLIQFYKSTRYKPTRIIFYRDGVSEGQFRQVLYYELLAIREACISLEKEYQPGITYIVV-----------------GRSGNIPAGTTVDTDITHPYEFDFYLCSHAGIQGTSRPSHYHVLWDDNCFTADEFQLLTYQLCHTYVRCTRSVSIPAPAYYAHLVAFRARYHLVDKEHDSAEGSHVSGQSNGRDPQALAKAVQIHHDTLRTMYFA 774

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BLAST of AGO-2 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000009610.1 (pep scaffold:Pmarinus_7.0:GL477777:44890:66775:1 gene:ENSPMAG00000008651.1 transcript:ENSPMAT00000009610.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 1069.3 bits (2764), Expect = 0.000e+0
Identity = 509/711 (71.59%), Postives = 595/711 (83.68%), Query Frame = 1

Query:  277 FQPPSRPDQGTDGRTIQLKANHFEIVMPKGFLHHYDITITPEKCPRRVNRDIIQAMVNNMHYQKYFYNQKPVFDGRRNMYTREPLSIGKEKLELEVILPGEGKDRVFKVCLKHVSEVSLFALEEALQGRRQTIPAETVTALDVIMRHLPSMTYTPVGRSFFHNTGDYDNPLGGGREVWFGFHQSVRPSQWKMMLNIDVSATAFYKEQSVINFMFEVLEID--KDLKRPLTDSQRVKFTKEIKGLKVEINHCGPIKRKYRVCNVTRRSAQSQTFPLQSEQGQTIECTVTKYFQDRYGMKLQHPHLPCLQVGQEQKHTYLPLEVCNIVSGQRCIKKLTDMQTSTMIKATARSAPDREKEINNLVRRSNFNADPHLQIFGVSVNTRMADIQGRVIPAPKIQYGGRTKAQATPQQGVWDMRGKQFFSGIEIKVWAIACFAPQRTVREDSLRTFTQQLQKISNDAGMPIVGQPCFCKYATGQDQVEPMFRYLKNSFSGLQLIVVVLPGKTPVYAEVKRVGDIIFGLATQCVQAKNVNKPSPQTLSNLCLKINVKLGGINSILVPSVRPAVFKEPVIFLGADFTHPPAGDKTKPSIAAVVGSMDAHPSRYAATVSVQPHRQETIQDLAAMVKELLIQFYKSTRFKPTRIIYYRDGVSEGQFLNVLNHELKAIREACIKLEMSYQPGITFVVVQKRHHTRLFCSDKKDQMGRSGNIPA 2403
            FQ P RP  GT G+ IQL+AN+FE+ +PK  L HYDI I PEKCPRRVNR++++ MV +  + K F ++KPVFDGR+N+YT  PL IG++++ELEV LPGEGK+RVFKV +K ++ VSL  L EAL GR   IP E++  LDV+MRHLPSM YTPVGRSFF     Y  PLGGGREVWFGFHQSVRP  WKMMLNIDVSATAFYK Q VI FM EVL++   ++  RPL+DSQRVKFTKEIKGLKVEI HCG +KRKYRVCNVTRR A  QTFPLQ E GQT+ECTV +YF+D+Y + L++ HLPCLQVGQE+KHTYLPLEVCNIV+GQRCIKKLTD QTSTMIKATARSAPDR++EI+ L++ ++FN+DP+++ FG+ V   MAD+QGRV+  P +QYGGRT+A ATP QGVWDMRGKQFF+GIEIKVWAIACFAPQR  RE+ L+ FT QL+KIS DAGMPI GQPCFCKYA G + VEPMFR+LKN++ GLQLIVV+LPGKTPVYAEVKRVGD + G+ATQCVQ KNV K SPQTLSNLCLKINVKLGG+N+ILVP +RPAVF++PVIFLGAD THPPAGD  KPSIAAVVGSMDAHPSRY ATV VQ HRQE I DL++MV+ELLIQFYKSTRFKPTRII+YRDGVSEGQF  VL HEL AIREACI+LE  Y+PGITF+VVQKRHHTRLFC+D+ +++  +   PA
Sbjct:   24 FQAPLRPGFGTVGKPIQLRANYFEVDIPKMDLLHYDIDIKPEKCPRRVNREVVEHMVQHFKH-KIFGDRKPVFDGRKNLYTVTPLPIGRDRVELEVTLPGEGKERVFKVTIKWMANVSLQLLHEALSGRLAQIPYESIQGLDVVMRHLPSMRYTPVGRSFFTPPEGYSQPLGGGREVWFGFHQSVRPCMWKMMLNIDVSATAFYKAQPVIEFMCEVLDLRTVEEQPRPLSDSQRVKFTKEIKGLKVEITHCGQMKRKYRVCNVTRRPAAQQTFPLQLESGQTVECTVAQYFRDKYKLHLKYAHLPCLQVGQEEKHTYLPLEVCNIVAGQRCIKKLTDNQTSTMIKATARSAPDRQEEISRLMKSASFNSDPYVREFGIMVKDDMADVQGRVLNPPMLQYGGRTRAVATPNQGVWDMRGKQFFTGIEIKVWAIACFAPQRQCREEVLKNFTDQLRKISKDAGMPIQGQPCFCKYAQGAENVEPMFRHLKNAYMGLQLIVVILPGKTPVYAEVKRVGDTLLGMATQCVQVKNVLKTSPQTLSNLCLKINVKLGGVNNILVPHIRPAVFQQPVIFLGADVTHPPAGDGKKPSIAAVVGSMDAHPSRYCATVRVQQHRQEIIHDLSSMVRELLIQFYKSTRFKPTRIIFYRDGVSEGQFQQVLYHELLAIREACIRLEKEYRPGITFIVVQKRHHTRLFCADRNERVSDACKSPA 733

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BLAST of AGO-2 vs. Ensembl Sea Lamprey
Match: ago2 (argonaute RISC catalytic component 2 [Source:ZFIN;Acc:ZDB-GENE-110606-6])

HSP 1 Score: 467.618 bits (1202), Expect = 1.413e-158
Identity = 222/278 (79.86%), Postives = 243/278 (87.41%), Query Frame = 1

Query: 1954 RPAVFKEPVIFLGADFTHPPAGDKTKPSIAAVVGSMDAHPSRYAATVSVQPHRQETIQDLAAMVKELLIQFYKSTRFKPTRIIYYRDGVSEGQFLNVLNHELKAIREACIKLEMSYQPGITFVVVQKRHHTRLFCSDKKDQMGRSGNIPAG-TTVDQIITHPTEFDFYLCSHAGIQGTSRPSHYHVLWDDNRFSADEIQTLTYQLCHTYVRCTRSVSIPAPAYYAHLVAFRARYHLVEKELDSGEGSQKSGNSDERNPTAMMRAVTVHSETLKVMYFA 2784
            RPAVF +PVIFLGA+ THPPAGD  KPSIAAVVGSMDAHPSRY ATV VQ HRQE IQDL  MV+ELLIQFYKSTRFKPTRII+YRDGVSEGQF  VL HEL AIR+ACIKLE  YQPGIT+V VQKRHHTRLFC+D+ +++G+SGNIPAG TTVD  ITHP+EFDFYLCSHAGIQGTSRPSHYHVLWDDNRFSADE+Q LTYQLCHTYVRCTRSVSIPAPAYYA LVAFRARYHLV+KE DS EGS  SG S+ R+  A+ +AV VH +TL+ MYFA
Sbjct:    2 RPAVFHQPVIFLGAEVTHPPAGDGKKPSIAAVVGSMDAHPSRYCATVRVQHHRQEIIQDLGTMVRELLIQFYKSTRFKPTRIIFYRDGVSEGQFQQVLFHELLAIRDACIKLEKDYQPGITYVAVQKRHHTRLFCADRNERIGKSGNIPAGTTTVDTKITHPSEFDFYLCSHAGIQGTSRPSHYHVLWDDNRFSADELQVLTYQLCHTYVRCTRSVSIPAPAYYARLVAFRARYHLVDKEHDSAEGSHVSGASNGRDAQALAKAVQVHVDTLRTMYFA 279

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BLAST of AGO-2 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000009316.1 (pep scaffold:Pmarinus_7.0:GL484064:2408:13690:1 gene:ENSPMAG00000008422.1 transcript:ENSPMAT00000009316.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 433.721 bits (1114), Expect = 1.484e-144
Identity = 213/325 (65.54%), Postives = 256/325 (78.77%), Query Frame = 1

Query:  274 YFQPPSRPDQGTDGRTIQLKANHFEIVMPKGFLHHYDITITPEKCPRRVNRDIIQAMVNNMHYQKYFYNQKPVFDGRRNMYTREPLSIGKEKL-ELEVILPGEGKDRVFKVCLKHVSEVSLFALEEALQGRRQTIPAETVTALDVIMRHLPSMT-YTPVGRSFFHNTGDYDNPLGGGREVWFGFHQSVRPSQWKMMLNIDVSATAFYKEQSVINFMFEVLEIDK--DLKRPLTDSQRVKFTKEIKGLKVEINHCGPIKRKYRVCNVTRRSAQSQTFPLQSEQGQTIECTVTKYFQDRYGMKLQHPHLPCLQVGQEQKHTYLPLEV 1236
            + Q P RP  GT G+ I+L AN+FE+ +PK  +HHYD+ I PEKCPRRVNR+++  +VN  + Q +F ++KPVFDGR+N+YT   L +G++K+ ELEV LPGEGKDRVFKV LK V  VS  AL +AL GR   +P + V A+DV++RHLPSM  YTPVGRSFF +   Y +PLGGGREVWFGFHQSVRPS WKMMLNIDVSATAFYK Q VI FM EVL+I    +  +PLTDSQRVKFTKEIKGLKVEI HCG +KRKY+VCNVTRR A  QTFPLQ + GQT+ECTV  YF+DR+ ++L++ HLPCLQVGQEQKHTYLPLEV
Sbjct:   17 HLQAPRRPGLGTVGKHIKLLANYFEVDIPKIEVHHYDLDIKPEKCPRRVNREVVDYLVNRSNVQ-FFRDRKPVFDGRKNLYTASALPVGRDKVVELEVTLPGEGKDRVFKVALKWVGYVSWHALHDALAGRIMQVPQDPVQAVDVVLRHLPSMRRYTPVGRSFFSSPEGYSHPLGGGREVWFGFHQSVRPSMWKMMLNIDVSATAFYKAQPVIEFMCEVLDIRNIDEQPKPLTDSQRVKFTKEIKGLKVEITHCGQMKRKYKVCNVTRRPASHQTFPLQLDTGQTVECTVAHYFRDRHKLQLKYAHLPCLQVGQEQKHTYLPLEV 340

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BLAST of AGO-2 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000009143.1 (pep scaffold:Pmarinus_7.0:GL477723:307292:327713:-1 gene:ENSPMAG00000008265.1 transcript:ENSPMAT00000009143.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 409.068 bits (1050), Expect = 3.150e-134
Identity = 199/401 (49.63%), Postives = 280/401 (69.83%), Query Frame = 1

Query:  277 FQPPSRPDQGTDGRTIQLKANHFEIVMPKGFLHHYDITITPEKCPRRVNRDIIQAMVNNMHYQKYFYNQKPVFDGRRNMYTREPLSIGKEKLELEVILPGEGKDRVFKVCLKHVSEVSLFALEEALQGRRQTIPAETVTALDVIMRHLPSMTYTPVGRSFFHNTGDYDNPLGGGREVWFGFHQSVRPSQWKMMLNIDVSATAFYKEQSVINFMFEVLEIDK--DLKRPLTDSQRVKFTKEIKGLKVEINHCGPIKRKYRVCNVTRRSAQSQTFPLQSEQGQTIECTVTKYFQDRYGMKLQHPHLPCLQVGQEQKHTYLPLEVCNIVSGQRCIKKLTDMQTSTMIKATARSAPDREKEINNLVRRSNFNADPHLQIFGVSVNTRMADIQGRVIPAPKIQYGG 1473
            FQPP RP  G+ GRTI+L+AN F++ +PKGFL HY++ + P+KCPRRVNR+++  MV   HY++ F  +KPV+DGR+N+YT  PL IG +++ L+  +    KD VF   ++++S    +A         Q+   +T     ++++H  +    P G  +F  +  +  P+ G         ++V P  +K ML + VSATAFYK Q V+ F+ E+L +    D ++PLTDSQRV FTKEI GLKVEI HCG +KRKYRVC+V+R+SA  QTFPLQ E GQT+EC+V  YF++++ ++L++PHLPCLQVGQ++KHTYLPLEVCNIV GQRCI++LTD QTSTMIKATARSAPDR++EI+ L++ +NF  DP ++ F + V   M ++ GRV+PAP +QYGG
Sbjct:    1 FQPPLRPSLGSLGRTIRLQANFFQVDIPKGFLQHYEVEVKPDKCPRRVNREVVLHMVQ--HYKQIFGERKPVYDGRQNLYTATPLPIGWDRVNLQCSILANAKDLVFFNSIEYISSYIDYAENVLKNDIIQSSVYDTFQCQPLVLKHRQTHRICPAGCEYFVLSQGWQCPVRG---------KAVCPCLFKRMLAMAVSATAFYKAQPVVEFLCEILGVHSLDDQRKPLTDSQRVAFTKEITGLKVEITHCGQMKRKYRVCSVSRKSASHQTFPLQLESGQTVECSVAHYFREKHKLQLRYPHLPCLQVGQKEKHTYLPLEVCNIVPGQRCIRRLTDSQTSTMIKATARSAPDRQEEISKLMKNANFKGDPFMREFEIRVRDDMTEVTGRVLPAPMLQYGG 390

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BLAST of AGO-2 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000009140.1 (pep scaffold:Pmarinus_7.0:GL477723:307292:327713:-1 gene:ENSPMAG00000008265.1 transcript:ENSPMAT00000009140.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 399.438 bits (1025), Expect = 1.831e-130
Identity = 202/407 (49.63%), Postives = 281/407 (69.04%), Query Frame = 1

Query:  277 FQPPSRPDQGTDGRTIQLKANHFEIVMPKGFLHHYDITITPEKCPRRVNRDIIQAMVNNMHYQKYFYNQKPVFDGRRNMYTREPLSIGKEKLELEVILPGEGKD----RVFKVCLKHVSEVSLFALEEALQGRRQTIP--AETVTALDVIMRHLPSMTYTPVGRSFFHNTGDYDNPLGGGREVWFGFHQSVRPSQWKMMLNIDVSATAFYKEQSVINFMFEVLEIDK--DLKRPLTDSQRVKFTKEIKGLKVEINHCGPIKRKYRVCNVTRRSAQSQTFPLQSEQGQTIECTVTKYFQDRYGMKLQHPHLPCLQVGQEQKHTYLPLEVCNIVSGQRCIKKLTDMQTSTMIKATARSAPDREKEINNLVRRSNFNADPHLQIFGVSVNTRMADIQGRVIPAPKIQYGG 1473
            FQPP RP  G+ GRTI+L+AN F++ +PKGFL HY++ + P+KCPRRVNR+++  MV   HY++ F  +KPV+DGR+N+YT  PL IG ++ + +     EG+     ++  V L  +   +L  ++E  Q    T+   A+  T  D + R  P +   P G  +F  +  +  P+ G         ++V P  +K ML + VSATAFYK Q V+ F+ E+L +    D ++PLTDSQRV FTKEI GLKVEI HCG +KRKYRVC+V+R+SA  QTFPLQ E GQT+EC+V  YF++++ ++L++PHLPCLQVGQ++KHTYLPLEVCNIV GQRCI++LTD QTSTMIKATARSAPDR++EI+ L++ +NF  DP ++ F + V   M ++ GRV+PAP +QYGG
Sbjct:    1 FQPPLRPSLGSLGRTIRLQANFFQVDIPKGFLQHYEVEVKPDKCPRRVNREVVLHMVQ--HYKQIFGERKPVYDGRQNLYTATPLPIGWDRADWDGSSIREGQREPPAKLHVVDLPLLCWTTLHDVQEGTQ-HVATVEHDAQISTVSDGVARGCPVLAVCPAGCEYFVLSQGWQCPVRG---------KAVCPCLFKRMLAMAVSATAFYKAQPVVEFLCEILGVHSLDDQRKPLTDSQRVAFTKEITGLKVEITHCGQMKRKYRVCSVSRKSASHQTFPLQLESGQTVECSVAHYFREKHKLQLRYPHLPCLQVGQKEKHTYLPLEVCNIVPGQRCIRRLTDSQTSTMIKATARSAPDRQEEISKLMKNANFKGDPFMREFEIRVRDDMTEVTGRVLPAPMLQYGG 395

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BLAST of AGO-2 vs. Ensembl Nematostella
Match: EDO46431 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RQ46])

HSP 1 Score: 1179.85 bits (3051), Expect = 0.000e+0
Identity = 559/843 (66.31%), Postives = 674/843 (79.95%), Query Frame = 1

Query:  277 FQPPSRPDQGTDGRTIQLKANHFEIVMPKGFLHHYDITITPEKCPRRVNRDIIQAMVNNMHYQKYFYNQKPVFDGRRNMYTREPLSIGKEKLELEVILPGEG-KDRVFKVCLKHVSEVSLFALEEALQGRRQTIPAETVTALDVIMRHLPSMTYTPVGRSFFHNTGDYDNPLGGGREVWFGFHQSVRPSQWKMMLNIDVSATAFYKEQSVINFMFEVLEIDKD-LKR--PLTDSQRVKFTKEIKGLKVEINHCGPIKRKYRVCNVTRRSAQSQTFPLQSEQGQTIECTVTKYFQDRYGMKLQHPHLPCLQVGQEQKHTYLPLEVCNIVSGQRCIKKLTDMQTSTMIKATARSAPDREKEINNLVRRSNFNADPHLQIFGVSVNTRMADIQGRVIPAPKIQYGGRTKAQATPQQ--GVWDMRGKQFFSGIEIKVWAIACFAPQRTVREDSLRTFTQQLQKISNDAGMPIVGQPCFCKYATGQDQVEPMFRYLKNSFSGLQLIVVVLPGKTPVYAEVKRVGDIIFGLATQCVQAKNVNKPSPQTLSNLCLKINVKLGGINSILVPSVRPAVFKEPVIFLGADFTHPPAGDKTKPSIAAVVGSMDAHPSRYAATVSVQPHRQETIQDLAAMVKELLIQFYKSTRFKPTRIIYYRDGVSEGQFLNVLNHELKAIREACIKLEMSYQPGITFVVVQKRHHTRLFCSDKKDQMGRSGNIPAGTTVDQIITHPTEFDFYLCSHAGIQGTSRPSHYHVLWDDNRFSADEIQTLTYQLCHTYVRCTRSVSIPAPAYYAHLVAFRARYHLVEKELDSG-EGSQKSGNSDERNPTAMMRAVTVHSETLKVMYFA 2784
            F PP RP+ G+ GRTI L+AN F + +P+G +HHYD++I P+KCPRRVNRD+++ MV N  Y K F   KPVFDGR+N+YTR+PL IGK   E EV+LP +  +D+ FKV LK VS+VSL+ALE+AL+G    IP ET+ ALDV++RHLPSM YTPVGRSFF     YD PL  GREVWFGFHQS+RPSQWKM+LNIDVSATAFYK QSV+ FM EVL I KD L++  PL D+ R++FT+EIKGLKVEI HCGP+KRKYRV NVT++ AQ+  FPL  E GQT + TV +YFQD++  +L++PHLPCLQVGQEQ+HTYLPLEVCNIV GQRC+KKLTD QTS MI+ATARSAPDRE+EI  LV+++NF+ D +++ F +S+   M ++QGRV+P PK+ YGG+ + +       GVWDMRG+Q F GIEI+ WAIACF  Q+   EDSLR F+ QL KIS + GMPI   P F +YA   D+VE MFR LK +   LQ+I+VVLPGKTPVYAEVKRVGD + G+ TQC+Q KNV KPSPQTLSNLCLKIN KLGG+N+IL P +RP VF+EPVIFLGAD THP AGD  +PS+AAVVGSMDAHPSRY A+V VQ HRQE I +LAAMV+ELL+QFY+STR KP RI++YRDGVSEGQF  VL HELKAIREACIKLE+ YQPGI+F+VVQKRHHTRLFC   +D+ G+SGN+P GTTVD+ ITHPTEFDFYLCSHAGIQGTSRPSHYHVLWDDN FSADE+Q LTYQLCHTYVRCTR+VSIPAPAYYAHLVAFRARYH+++++ ++G + S  +   D R P  +  AV VH + L+ MYFA
Sbjct:   14 FNPPKRPNHGSTGRTIALRANFFPVQLPRGNIHHYDLSICPDKCPRRVNRDVVEVMVLN--YHKVFGGMKPVFDGRKNLYTRDPLPIGKTPTEFEVVLPTDNSQDKKFKVTLKWVSQVSLYALEKALEGTCNQIPFETIQALDVVLRHLPSMKYTPVGRSFFSPPDGYDFPLERGREVWFGFHQSIRPSQWKMLLNIDVSATAFYKCQSVVEFMCEVLRIRKDDLEKHAPLNDADRLRFTREIKGLKVEITHCGPMKRKYRVINVTKQPAQALQFPLTLESGQTAQITVARYFQDKHKQRLRYPHLPCLQVGQEQRHTYLPLEVCNIVPGQRCVKKLTDTQTSKMIRATARSAPDREREIRGLVKKANFDEDAYVKDFSISIGKNMVELQGRVLPPPKLVYGGKVRIEKIIHSFSGVWDMRGRQLFHGIEIRTWAIACFVKQQMCTEDSLRRFSNQLMKISVEQGMPISCPPVFFRYARNPDEVERMFRRLKEAHPDLQMILVVLPGKTPVYAEVKRVGDTMLGVITQCIQGKNVTKPSPQTLSNLCLKINAKLGGVNNILAPEIRPPVFREPVIFLGADVTHPAAGDDKRPSVAAVVGSMDAHPSRYYASVRVQTHRQEIIAELAAMVRELLVQFYRSTRHKPQRIVFYRDGVSEGQFRQVLVHELKAIREACIKLEVGYQPGISFIVVQKRHHTRLFCQRDQDKCGKSGNVPPGTTVDRGITHPTEFDFYLCSHAGIQGTSRPSHYHVLWDDNNFSADELQALTYQLCHTYVRCTRAVSIPAPAYYAHLVAFRARYHMMDRDKEAGNDNSSVASGEDCRGPQLLANAVQVHPKVLQGMYFA 854

[Close]

BLAST of AGO-2 vs. Ensembl Nematostella
Match: EDO38583 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SCI6])

HSP 1 Score: 614.379 bits (1583), Expect = 0.000e+0
Identity = 332/757 (43.86%), Postives = 461/757 (60.90%), Query Frame = 1

Query:  286 PSRPDQGTDGRTIQLKANHFEIVMPK-GFLHHYDITITPEKCPRRVNRDIIQAMVNNMHYQKYFYNQKPVFDGRRNMYTREPLSIGKEKLELEVILPGE--GKDRVFKVCLKHVSEVSLFALEEALQGR-RQTIPAETVTALDVIMRHLPSMTYTPVGRSFFHNTGDYDNPLGGGREVWFGFHQSVRPSQWK-MMLNIDVSATAFYKEQSVINFMFEVLEIDK----DLKRPLTDSQRVKFTKEIKGLKVEINHCGPIKRKYRVCNVTRRSAQSQTFPLQSEQGQTIECTVTKYFQDRYGMKLQHPHLPCLQVGQEQKHTYLPLEVCNIVSGQRCIKKLTDMQTSTMIKATARSAPDREKEINNLVRRSNFNADPHLQ-IFGVSVNTRMADIQGRVIPAPKIQYGGRTKAQA-TPQQGVWDMRGKQFFSGIEIKVWAIACFAPQRTVREDSLRTFTQQLQKISNDAGMPIVGQPCFCKYATGQDQVEPMFRYLKNSFSGLQLIVVVLP--GKTPVYAEVKRVGDIIFGLATQCVQAKNVNKPSPQTLSNLCLKINVKLGGINSILVPSVRP--------AVFKEPVIFLGADFTHPPAGDKTKPSIAAVVGSMDAHPSRYAATVSVQPHR-----QETIQDLAAMVKELLIQFYKSTRFKPTRIIYYRDGVSEGQFLNVLNHELKAIREACIKLEMSYQPGITFVVVQKRHHTRLFCSDKKDQMGRSGNIPAGTTVDQIITHPTEFDFYLCSHAGIQ 2478
            P RP  G +GR I+L+AN F++ +P   FL+HYD+ I+PEK P  V RD++ A + +  ++  F   KP FDGRRN+Y REPL +  E+  L+V LPG   GK+R F + +K    VS+  L++ L G  R  +P + +  +D+++R +PSM +T VGR FF     + + LGGG E+W GF+QSVRPSQWK M+LNIDVS+  F K   VI+FM E+L  D+    D +  + +  + K T EIKGL+VE  H   IKRK+ V  ++   A +  F L+       E TV  YF+++Y + L++PHLPCL VGQ  K   +P+EVCN++  QR  K+LTD QT+ MI+ TA+ A +R+++IN  V      +D +L+  +G+ +N +M  I+GRV+PAP++  GG  +  A TP  G WDMRGK FF    ++VWA+ CF+  +   ++ L  F +Q+  +    GM +   PC  +YA+   +VE +F  L + F+ LQLIVV LP  G   VY EVKRVGD + G+ TQCVQ K      PQ  SN+ +KIN KLGG N ++  S++          +F  PVI  GAD THP  GD   PSIAAVV S++ + SRY A V  Q H      QE I DLA M   + I+ ++      T+ ++ R          VL  E++A+++AC  LE  YQP ITFVVVQKRHH RLF  + +D  G+S N+PAGTTVD +I HP EFDFYLCSHAGIQ
Sbjct:    7 PKRPGYGREGRKIKLRANFFQVTLPNVDFLYHYDLEISPEKAPVSVCRDVVDAAIKHGEFKGVFNGCKPAFDGRRNLYCREPLPLKSEEASLKVTLPGTDGGKERKFTLKIKEAGLVSIKELDQFLNGEFRGKVPQDAIQGMDIVLRQMPSMKFTAVGRCFFPPPNGHCHDLGGGCELWTGFYQSVRPSQWKTMLLNIDVSSKGFQKSMPVIDFMLEILRQDRNRVLDTRWVMDERDKKKLTTEIKGLRVETTH---IKRKFTVMGLSH-PAFNNRFRLED----NTETTVEAYFRNKYNISLRYPHLPCLLVGQ--KKNSVPMEVCNMIPTQR--KRLTDEQTAAMIRKTAKPANERQRDINQWVDELATASDQYLKNEYGMRINKQMVAIEGRVLPAPELTLGGNPQGSALTPSDGAWDMRGKSFFEARTVEVWALVCFSHPKWCPKEKLEGFARQMGNVCRSEGMRMNPVPCRAEYASRVQEVEGIFGKLLHDFNSLQLIVVALPDRGNKDVYNEVKRVGDTVLGIPTQCVQMKQFTMAKPQVCSNIAMKINGKLGGTNHVIADSLKATITDDKGNGIFNSPVIIFGADVTHPAPGDNGIPSIAAVVASLNRNASRYCARVRPQTHMKCKQAQEIIVDLADMDVHIYIRLWRKLESHDTQTMFRR--------FQVLLEEVRAVQQACAMLEKDYQPLITFVVVQKRHHARLFAEEGRDARGKSRNVPAGTTVDTVICHPFEFDFYLCSHAGIQ 743

[Close]

BLAST of AGO-2 vs. Ensembl Nematostella
Match: EDO49931 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RFC2])

HSP 1 Score: 194.126 bits (492), Expect = 4.483e-51
Identity = 201/824 (24.39%), Postives = 353/824 (42.84%), Query Frame = 1

Query:  280 QPPSRPD----QGTDGRTIQLKANHFEI-VMPKGFLHHYDITITPEKCPRRVNRDIIQAMVNNMHYQKYFYNQKPVFDGRRNMYTREPLSIGKEKLELEVILPGEGKDRVFKVCLKHVSEVSLFALEEALQGRRQTIPAETVTALD----VIMRHLPSMTYTPVGRSFFHNTGDYDNPLGGGREVWFGFHQSVRPSQWKMMLNIDVSATAFYKEQSVINFMFEVLEIDKDLKRPLTDSQRVKFTKEI-KGLKVEINHCGPIKRKYRVCNVTRRSAQSQTFPLQSEQGQTIECTVTKYFQDRYGMKLQHPHLPCL------QVGQEQKHTYLPLEVCNIVSGQRCIKK----LTDMQTSTMIKATARSAPDREKEINNLVRRSNFNADP--HLQIFGVSVNTRMADIQGRVIPAPKIQYGGRTKAQATPQQGVW--DMRGKQFFSGIEIKVWAIACFAPQRTVREDSLRT-FTQQLQKISNDAGMPIVGQPCFCKYATGQDQVEPMFRYLKNSFSGL--QLIVVVLP-GKTPVYAEVKRVGDIIFGLATQCVQAKNVNKPSPQTLSNLCLKI----NVKLGG-INSILVPSVRPAVFKEPVIFLGADFTHPPAGDKTKPSIAAVVGSMDAHPSR---YAATVSVQPHRQETIQDLAAMVKELLIQFYKSTRFKPTRIIYYRDGVSEGQFLNVLNHELKAIREACIKLEMSYQPGITFVVVQKRHHTRLFCSDKKD-QMGRSGNIPAGTTVDQIITHPTEFDFYLCSHAGIQGTSRPSHYHVLWDDNRFSADEIQTLTYQLCHTYVRCTRSVSIPAPAYYAHLVAF 2640
            +P +R D    +G+ G  + + +N+F +   P+  ++ Y+++ +PE        D  +A    +  Q+        FDG                  + + LP +  D+V K+        +     E        +PA++ T L     ++ R L  +    VGR++++       P   G E+W G+  S+   +  ++L  DVS     ++Q+V++F++E+               R  F  E  K L  EI       + YRV ++      + TF   + +G   E +   Y++  Y   +     P L      + G +     LP E+C +      ++     + D+   T +   ARS     K++N L+   N N D    L  +G+     + D  GR++P  KI +     +   P+   W  ++RG    S + ++ W I       T R+  + T F Q L ++    G+    +P         D+ +   + L N       Q++V ++P  +   Y  +K++  +  G+ +Q V ++ ++K   Q L ++C KI    N KLGG   ++ +P        + ++ +G D  H  +  +   S+   V S++   +R   Y +  + Q   QE +  L   +   L Q+ +     P +II +RDGV +GQ   V+ HE+  I     + +  Y P   F VV+KR  TRLF  + +D  M    N P GT VD+ +T    FDF++ S +  QGT  P+HY+V+ D      D  Q L+Y+L H Y     +V +PAP  YAH +AF
Sbjct:   94 EPTTRRDGFNKEGSVGTKVGIVSNYFRLETRPQAAIYQYNVSFSPEV-------DFKKARFALIGEQRELLGNIRAFDG------------------MVLFLPKKLPDQVTKIMAVRTRRETPDEPVEITITLTNELPADSPTCLHLFNIILKRILKYIDMKQVGRNYYYIKNAIAIP-KHGLELWPGYTTSILKYEHSILLGADVSHKVL-RKQTVLDFLYELYN---------KMQGRGNFHDEAAKKLVGEIVLTRYNNKTYRVDDIDWNKRPNSTF--TTPKG---EISFNDYYKKNYDFTITDQEQPLLFSKPKKRKGADDPVLLLP-ELCFLTGLSDDMRADFSVMKDLAVHTRLDPKARS-----KDLNKLISEINNNPDASGELSGWGLRFGRNLLDFDGRILPGEKI-FQKNKGSNYDPKSADWSREIRGAPLHSTVNLENWVIV-----HTNRDSGVATDFQQTLARVCGPMGINTT-KPRMV--PLNDDRTDSYLKALSNEIQADFPQIVVTIVPSNRKDRYDSIKKLCCLEKGVPSQVVVSRTLSKK--QMLMSVCTKIGIQLNCKLGGEAWAVDIPL-------KNLMIVGIDTYHDSS--QKGRSVGGFVASLNKPCTRQREYYSRCTFQHSGQELVDGLKVCMTAALRQWQQINGVLPDKIIVFRDGVGDGQLRAVIEHEVPQILSTFKQFQDGYDPKFGFTVVKKRIQTRLFMREARDPDMRNLMNPPPGTVVDKEVTRSEWFDFFIVSQSVRQGTVSPTHYNVIHDTTGLRPDHWQQLSYKLTHLYYNWPGTVRVPAPCQYAHKLAF 850

[Close]

BLAST of AGO-2 vs. Ensembl Nematostella
Match: EDO34027 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SQI3])

HSP 1 Score: 176.792 bits (447), Expect = 6.779e-46
Identity = 162/631 (25.67%), Postives = 284/631 (45.01%), Query Frame = 1

Query:  805 VWFGFHQSVRPSQWKMMLNIDVSATAFYKEQSVINFMFEVLEIDKDLKRPLTDSQRVKFTKEIKGLKVEINHCGPIKRKYRVCNVTRRSAQSQTFPLQSEQGQTIECTVTKYFQDRYGMK---LQHPHLPCLQVGQEQKH------TYLPLEVCNIVSGQRCIKKLTDMQTSTMIKATARSAP-DREKEINNLVRRSNFN--ADPHLQIFGVSVNTRMADIQGRVIPAPKIQYGGRTKAQATPQQGVWDMRGKQFFSGIEIKVWAIACFAPQRTVREDSLRTFTQQLQKISNDAGMPIVGQPCFCKYATGQDQVEPMFRYLK-NSFSGLQLIVVVLP-GKTPVYAEVKRVGDIIFGLATQCVQAKNVNKPSP--QTLSNLCLKINVKLGG-INSILVPSVRPAVFKEPVIFLGADFTHPPAGDKTKPSIAAVVGSMDAHPSRYAATVSVQPHRQETIQDLAAMVKELLIQFYKSTRFKPTRIIYYRDGVSEGQFLNVLNHELKAIREACIKLEMSYQPGITFVVVQKRHHTRLFCSDKKDQMGRSGNIPAGTTVDQIITHPTEFDFYLCSHAGIQGTSRPSHYHVLWDDNRFSADEIQTLTYQLCHTYVRCTRSVSIPAPAYYAHLVAFRA 2646
            +W G+  S++  +  +ML  DV      +  S +++M        ++   + D  R + +KE+ G  V   +     + YRV ++      + TF   + +    + T  +Y++  Y ++   L  P +       EQK         L  E+C +      ++K  D +    I A  R  P  R++ +   V   N    A   L  + + ++T     +GR  P  KI YG  T +         D   ++  S + +  W +  F  QR         F Q + K +   G+  V QP   +     D+ E   R ++ N    +Q++VV+ P  +   YA VK++  +   + +Q + +K ++ P+     +  + L+INVKLGG + ++ +PS         ++  G D  H  A  +   S+  +V SM+   +R+ + V  Q   QE I  L  ++ + + +++      P RII YRDGV +GQ   V  +E++   E       SY+P +  +VVQKR +TR+F ++      R GN   G+ +D  +T     DF+L S    QGT  P+HY V++D + +  D +Q L+Y+L H Y     +V +PAP  YAH +A++ 
Sbjct:  136 LWPGYITSLQHYEGGLMLLCDVHH-RLLRTDSCLDYML-------NMHSKVGDRFRDEVSKELIGSVVLTTYNN---KTYRVDDIDWNKRPTSTFTFHNGE----QMTFVEYYKKSYEIEIRDLDQPMIVNRPKKTEQKRGGVIEVILLIPELCKLTGLNDAMRK--DFRVMKDIAAHTRVNPMQRQEAMKKFVMSINSTPEALEQLTAWNLRLDTSTLMTEGRQFPPEKIIYGNTTGSAGDQADWGRDATREKVISAVNLNNWMV--FFTQRD--SGKANDFVQTMNKCAPAMGIQ-VNQPKMNQLR--DDRTETYLRSIRENLHPQVQVVVVIFPTSRDDRYAAVKKLCCVESPVPSQVIISKTISNPTKLRSVVQKIALQINVKLGGELWALDIPS-------RSLMVCGIDVYHDKA--RGGRSVGGLVCSMNRSLTRWYSDVCFQSPGQELIDGLKMLLIKGIRKWHDVNNALPERIIVYRDGVGDGQLKVVAGYEVQQFEECFASFGESYKPKLAVLVVQKRINTRIFSAEP-----RLGNPGPGSVLDHTVTRKDWNDFFLVSQHVRQGTVTPTHYVVVYDTSNWKPDIMQKLSYKLTHLYYNWPGTVRVPAPCQYAHKLAYQV 728

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BLAST of AGO-2 vs. Ensembl Nematostella
Match: EDO38584 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SCI7])

HSP 1 Score: 77.7962 bits (190), Expect = 9.457e-18
Identity = 34/66 (51.52%), Postives = 48/66 (72.73%), Query Frame = 1

Query:  673 IPAETVTALDVIMRHLPSMTYTPVGRSFFHNTGDYDNPLGGGREVWFGFHQSVRPSQWK-MMLNID 867
            +P + +  +D+++R +PSM +T VGR FF     + + LGGG E+W GF+QSVRPSQWK M+LNID
Sbjct:    1 VPQDAIQGMDIVLRQMPSMKFTAVGRCFFPPPNGHCHDLGGGCELWTGFYQSVRPSQWKTMLLNID 66

[Close]

BLAST of AGO-2 vs. Ensembl Medaka
Match: AGO2 (protein argonaute-2 [Source:NCBI gene;Acc:101156100])

HSP 1 Score: 1300.42 bits (3364), Expect = 0.000e+0
Identity = 620/838 (73.99%), Postives = 705/838 (84.13%), Query Frame = 1

Query:  277 FQPPSRPDQGTDGRTIQLKANHFEIVMPKGFLHHYDITITPEKCPRRVNRDIIQAMVNNMHYQKYFYNQKPVFDGRRNMYTREPLSIGKEKLELEVILPGEGKDRVFKVCLKHVSEVSLFALEEALQGRRQTIPAETVTALDVIMRHLPSMTYTPVGRSFFHNTGDYDNPLGGGREVWFGFHQSVRPSQWKMMLNIDVSATAFYKEQSVINFMFEVLEID--KDLKRPLTDSQRVKFTKEIKGLKVEINHCGPIKRKYRVCNVTRRSAQSQTFPLQSEQGQTIECTVTKYFQDRYGMKLQHPHLPCLQVGQEQKHTYLPLEVCNIVSGQRCIKKLTDMQTSTMIKATARSAPDREKEINNLVRRSNFNADPHLQIFGVSVNTRMADIQGRVIPAPKIQYGGRTKAQATPQQGVWDMRGKQFFSGIEIKVWAIACFAPQRTVREDSLRTFTQQLQKISNDAGMPIVGQPCFCKYATGQDQVEPMFRYLKNSFSGLQLIVVVLPGKTPVYAEVKRVGDIIFGLATQCVQAKNVNKPSPQTLSNLCLKINVKLGGINSILVPSVRPAVFKEPVIFLGADFTHPPAGDKTKPSIAAVVGSMDAHPSRYAATVSVQPHRQETIQDLAAMVKELLIQFYKSTRFKPTRIIYYRDGVSEGQFLNVLNHELKAIREACIKLEMSYQPGITFVVVQKRHHTRLFCSDKKDQMGRSGNIPAGTTVDQIITHPTEFDFYLCSHAGIQGTSRPSHYHVLWDDNRFSADEIQTLTYQLCHTYVRCTRSVSIPAPAYYAHLVAFRARYHLVEKELDSGEGSQKSGNSDERNPTAMMRAVTVHSETLKVMYFA 2784
            F+PPSRPD GT GRTI+L+AN FE+ +PK  ++HYDI I PEKCPRRVNR+I++ MV +   Q  F ++KPV+DGR+N+YT   L IG+EK+ELEV +PGEGKDR FKV +K VS VSL AL EAL GR  ++P ET+ ALDV+MRHLPSM YTPVGRSFF  +    NPLGGGREVWFGFHQSVRPS WKMMLNIDVSATAFYK Q VI FM EVL+    ++ ++PLTDSQRVKFTKEIKGLKVEI HCG +KRKYRVCNVTRR A  QTFPLQ E GQTIECTV +YF+D+Y + L++PHLPCLQVGQEQKHTYLPLEVCNIV+GQRCIKKLTD QTSTMI+ATARSAPDR+ EI+ L+R +NFN DP+++ FGV V   M ++ GRV+ AP I YGGR KA ATP QGVWDMR KQF +GIEIKVWAIACFAPQR   E  L+ FT QL+KIS DAGMPI GQPCFCKYA G D VEPMFR+LK ++ GLQL+VV+LPGKTPVYAEVKRVGD + G+ATQCVQ KNV K +PQTLSNLCLKINVKLGG+N+IL+P  RP VF++PVIFLG+D THPPAGD  KPSIAAVVGSMDAHPSRY ATV VQ HRQ+ IQDLA MV+ELLIQFYKSTRFKPTRIIYYRDG+SEGQF  VL HEL AIREACIKLE  YQPGITFVVVQKRHHTRLFC D+ +++G+SGNIPAGTTVD  ITHP+EFDFYLCSHAGIQGTSRPSHYHVLWDDN FS+DE+Q LTYQLCHTYVRCTRSVSIPAPAYYAHLVAFRARYHLV+KE DS EGS  SG S+ R+  A+ +AV +H +TL+ MYFA
Sbjct:   18 FKPPSRPDFGTMGRTIKLQANFFEMEIPKLEVYHYDIDIKPEKCPRRVNREIVEHMVQHFKTQ-IFGDRKPVYDGRKNLYTAMALPIGREKVELEVTIPGEGKDRSFKVAIKWVSCVSLQALHEALSGRLPSVPFETIQALDVVMRHLPSMRYTPVGRSFFTPSEACSNPLGGGREVWFGFHQSVRPSLWKMMLNIDVSATAFYKAQPVIEFMCEVLDFKSIEEQQKPLTDSQRVKFTKEIKGLKVEITHCGQMKRKYRVCNVTRRPASHQTFPLQQENGQTIECTVAQYFKDKYKLILRYPHLPCLQVGQEQKHTYLPLEVCNIVAGQRCIKKLTDNQTSTMIRATARSAPDRQDEISKLMRSANFNTDPYVREFGVMVRDEMTEVNGRVLQAPSILYGGRNKAIATPIQGVWDMRNKQFHTGIEIKVWAIACFAPQRQCTELLLKAFTDQLRKISRDAGMPIQGQPCFCKYAQGADSVEPMFRHLKYTYQGLQLVVVILPGKTPVYAEVKRVGDTVLGMATQCVQVKNVQKTTPQTLSNLCLKINVKLGGVNNILLPQGRPMVFQQPVIFLGSDVTHPPAGDGKKPSIAAVVGSMDAHPSRYCATVRVQQHRQDIIQDLANMVRELLIQFYKSTRFKPTRIIYYRDGISEGQFNQVLQHELLAIREACIKLEKDYQPGITFVVVQKRHHTRLFCMDRNERVGKSGNIPAGTTVDTKITHPSEFDFYLCSHAGIQGTSRPSHYHVLWDDNHFSSDELQVLTYQLCHTYVRCTRSVSIPAPAYYAHLVAFRARYHLVDKEHDSAEGSHTSGQSNGRDHQALAKAVQIHQDTLRTMYFA 854

[Close]

BLAST of AGO-2 vs. Ensembl Medaka
Match: ago1 (protein argonaute-1 [Source:NCBI gene;Acc:101169483])

HSP 1 Score: 1261.13 bits (3262), Expect = 0.000e+0
Identity = 595/838 (71.00%), Postives = 702/838 (83.77%), Query Frame = 1

Query:  277 FQPPSRPDQGTDGRTIQLKANHFEIVMPKGFLHHYDITITPEKCPRRVNRDIIQAMVNNMHYQKYFYNQKPVFDGRRNMYTREPLSIGKEKLELEVILPGEGKDRVFKVCLKHVSEVSLFALEEALQGRRQTIPAETVTALDVIMRHLPSMTYTPVGRSFFHNTGDYDNPLGGGREVWFGFHQSVRPSQWKMMLNIDVSATAFYKEQSVINFMFEVLEIDKDLKRP--LTDSQRVKFTKEIKGLKVEINHCGPIKRKYRVCNVTRRSAQSQTFPLQSEQGQTIECTVTKYFQDRYGMKLQHPHLPCLQVGQEQKHTYLPLEVCNIVSGQRCIKKLTDMQTSTMIKATARSAPDREKEINNLVRRSNFNADPHLQIFGVSVNTRMADIQGRVIPAPKIQYGGRTKAQATPQQGVWDMRGKQFFSGIEIKVWAIACFAPQRTVREDSLRTFTQQLQKISNDAGMPIVGQPCFCKYATGQDQVEPMFRYLKNSFSGLQLIVVVLPGKTPVYAEVKRVGDIIFGLATQCVQAKNVNKPSPQTLSNLCLKINVKLGGINSILVPSVRPAVFKEPVIFLGADFTHPPAGDKTKPSIAAVVGSMDAHPSRYAATVSVQPHRQETIQDLAAMVKELLIQFYKSTRFKPTRIIYYRDGVSEGQFLNVLNHELKAIREACIKLEMSYQPGITFVVVQKRHHTRLFCSDKKDQMGRSGNIPAGTTVDQIITHPTEFDFYLCSHAGIQGTSRPSHYHVLWDDNRFSADEIQTLTYQLCHTYVRCTRSVSIPAPAYYAHLVAFRARYHLVEKELDSGEGSQKSGNSDERNPTAMMRAVTVHSETLKVMYFA 2784
            F  P RP  GT G+ I+L AN+FE+ +PK  ++HY++ I P+KCPRRVNR++++ MV +   Q  F ++KPV+DG++N+YT   L IG EK++ EV +PGEGKDR+FKV ++ +++VS   L+E L   R  +P ++V ALDV MRHL SM YTPVGRSFF     Y +PLGGGREVWFGFHQSVRP+ WKMMLNIDVSATAFYK Q VI FM EVL+I    ++P  LTDSQRV+FTKEIKGLKVE+ HCG +KRKYRVCNVTRR A  QTFPLQ E GQT+ECTV +YF+ +Y ++L++PHLPCLQVGQEQKHTYLPLEVCNIV+GQRCIKKLTD QTSTMIKATARSAPDR++EI+ L++ +NFN DP++Q FG+ V   MA++ GRV+PAP +QYGGR +A ATP QGVWDMRGKQF++GIEIKVWAIACFAPQ+  RE+ L+ FT QL+KIS DAGMPI GQPCFCKYA G D VEPMFR+LKN++SGLQLI+V+LPGKTPVYAEVKRVGD + G+ATQCVQ KNV K SPQTLSNLCLKINVKLGGIN+ILVP  R AVF++PVIFLGAD THPPAGD  KPSI AVVGSMDAHPSRY ATV VQ  RQE I+DL+ MV+ELLIQFYKSTRFKPTRII+YRDGV EGQ   +L++EL AIR+ACIKLE  YQPGIT++VVQKRHHTRLFC+DK +++G+SGNIPAGTTVD  ITHP EFDFYLCSHAGIQGTSRPSHY+VLWDDNRF+ADE+Q LTYQLCHTYVRCTRSVSIPAPAYYA LVAFRARYHLV+KE DSGEGS  SG S+ R+P A+ +AV +H +TL+ MYFA
Sbjct:   22 FHAPRRPGMGTVGKPIKLLANYFEVEIPKMDVYHYEVDIKPDKCPRRVNREVVEYMVQHFKPQ-LFGDRKPVYDGKKNIYTVLALPIGSEKVDFEVTIPGEGKDRIFKVSIRWLAKVSWRLLQETLVSGRLQVPLDSVQALDVAMRHLASMRYTPVGRSFFSPPEGYYHPLGGGREVWFGFHQSVRPAMWKMMLNIDVSATAFYKAQPVIEFMCEVLDIRNIDEQPKTLTDSQRVRFTKEIKGLKVEVTHCGQMKRKYRVCNVTRRPASHQTFPLQLESGQTVECTVAQYFKQKYNLQLKYPHLPCLQVGQEQKHTYLPLEVCNIVAGQRCIKKLTDNQTSTMIKATARSAPDRQEEISRLMKNANFNLDPYIQEFGIKVKDDMAEVTGRVLPAPILQYGGRNRAIATPNQGVWDMRGKQFYNGIEIKVWAIACFAPQKQCREEVLKNFTDQLRKISKDAGMPIQGQPCFCKYAQGADSVEPMFRHLKNTYSGLQLIIVILPGKTPVYAEVKRVGDTLLGMATQCVQVKNVVKTSPQTLSNLCLKINVKLGGINNILVPHQRSAVFQQPVIFLGADVTHPPAGDGKKPSITAVVGSMDAHPSRYCATVRVQRPRQEIIEDLSYMVRELLIQFYKSTRFKPTRIIFYRDGVPEGQLPQILHYELLAIRDACIKLEKDYQPGITYIVVQKRHHTRLFCADKSERIGKSGNIPAGTTVDTSITHPFEFDFYLCSHAGIQGTSRPSHYYVLWDDNRFTADELQILTYQLCHTYVRCTRSVSIPAPAYYARLVAFRARYHLVDKEHDSGEGSHVSGQSNGRDPQALAKAVQIHHDTLRTMYFA 858

[Close]

BLAST of AGO-2 vs. Ensembl Medaka
Match: AGO2 (protein argonaute-2 [Source:NCBI gene;Acc:101156100])

HSP 1 Score: 1241.87 bits (3212), Expect = 0.000e+0
Identity = 602/839 (71.75%), Postives = 680/839 (81.05%), Query Frame = 1

Query:  277 FQPPSRPDQGTDGRTIQLKANHFEIVMPKGFLHHYDITITPEKCPRRVNRDIIQAMVNNMHYQKYFYNQKPVFDGRRNMYTREPLSIGKEKLELEVILPGEGKDRVFKVCLKHVSEVSLFALEEALQGRRQTIPAETVTALDVIMRHLPSMTYTPVGRSFFHNTGDYDNPLGGGREVWFGFHQSVRPSQWKMMLNIDVSATAFYKEQSVINFMFEVLEID--KDLKRPLTDSQRVKFTKEIKGLKVEINHCGPIKRKYRVCNVTRRSAQSQTFPLQSEQGQTIECTVTKYFQDRYGMKLQHPHLPCLQVGQEQKHTYLPLEVCNIVSGQRCIKKLTDMQTSTMIKATARSAPDREKEINNLVRRSNFNADPHLQIFGVSVNTRMADIQGRVIPAPKIQYGGRTKAQATPQQGVWDMRGKQFFSGIEIKVWAIACFAPQRTVREDSLRTFTQQLQKISNDAGMPIVGQPCFCKYATGQDQVEPMFRYLKNSFSGLQLIVVVLPGKTPVYAEVKRVGDIIFGLATQCVQAKNVNKPSPQTLSNLCLKINVKLGGINSILVPSVRPAVFKEPVIFLGADFTHPPAGDKTKPSIAAVVGSMDAHPSRYAATVSVQPHRQETIQDLAAMVKELLIQFYKSTRFKPTRIIYYRDGVSEGQFLNVLNHELKAIREACIKLEMSYQPGITFVVVQKRHHTRLFCSDKKDQMGRSGNIPAGTTVDQIITHPTEFDFYLCSHAGI-------------------------------------QGTSRPSHYHVLWDDNRFSADEIQTLTYQLCHTYVRCTRSVSIPAPAYYAHLVAFRARYHLVEKELD 2676
            F+PPSRPD GT GRTI+L+AN FE+ +PK  ++HYDI I PEKCPRRVNR+I++ MV +   Q  F ++KPV+DGR+N+YT   L IG+EK+ELEV +PGEGKDR FKV +K VS VSL AL EAL GR  ++P ET+ ALDV+MRHLPSM YTPVGRSFF  +    NPLGGGREVWFGFHQSVRPS WKMMLNIDVSATAFYK Q VI FM EVL+    ++ ++PLTDSQRVKFTKEIKGLKVEI HCG +KRKYRVCNVTRR A  QTFPLQ E GQTIECTV +YF+D+Y + L++PHLPCLQVGQEQKHTYLPLEVCNIV+GQRCIKKLTD QTSTMI+ATARSAPDR+ EI+ L+R +NFN DP+++ FGV V   M ++ GRV+ AP I YGGR KA ATP QGVWDMR KQF +GIEIKVWAIACFAPQR   E  L+ FT QL+KIS DAGMPI GQPCFCKYA G D VEPMFR+LK ++ GLQL+VV+LPGKTPVYAEVKRVGD + G+ATQCVQ KNV K +PQTLSNLCLKINVKLGG+N+IL+P  RP VF++PVIFLG+D THPPAGD  KPSIAAVVGSMDAHPSRY ATV VQ HRQ+ IQDLA MV+ELLIQFYKSTRFKPTRIIYYRDG+SEGQF  VL HEL AIREACIKLE  YQPGITFVVVQKRHHTRLFC D+ +++G+SGNIPAGTTVD  ITHP+EFDFYLCSHAGI                                     QGTSRPSHYHVLWDDN FS+DE+Q LTYQLCHTYVRCTRSVSIPAPAYYAHLVAFRARYHLV+KE D
Sbjct:   74 FKPPSRPDFGTMGRTIKLQANFFEMEIPKLEVYHYDIDIKPEKCPRRVNREIVEHMVQHFKTQ-IFGDRKPVYDGRKNLYTAMALPIGREKVELEVTIPGEGKDRSFKVAIKWVSCVSLQALHEALSGRLPSVPFETIQALDVVMRHLPSMRYTPVGRSFFTPSEACSNPLGGGREVWFGFHQSVRPSLWKMMLNIDVSATAFYKAQPVIEFMCEVLDFKSIEEQQKPLTDSQRVKFTKEIKGLKVEITHCGQMKRKYRVCNVTRRPASHQTFPLQQENGQTIECTVAQYFKDKYKLILRYPHLPCLQVGQEQKHTYLPLEVCNIVAGQRCIKKLTDNQTSTMIRATARSAPDRQDEISKLMRSANFNTDPYVREFGVMVRDEMTEVNGRVLQAPSILYGGRNKAIATPIQGVWDMRNKQFHTGIEIKVWAIACFAPQRQCTELLLKAFTDQLRKISRDAGMPIQGQPCFCKYAQGADSVEPMFRHLKYTYQGLQLVVVILPGKTPVYAEVKRVGDTVLGMATQCVQVKNVQKTTPQTLSNLCLKINVKLGGVNNILLPQGRPMVFQQPVIFLGSDVTHPPAGDGKKPSIAAVVGSMDAHPSRYCATVRVQQHRQDIIQDLANMVRELLIQFYKSTRFKPTRIIYYRDGISEGQFNQVLQHELLAIREACIKLEKDYQPGITFVVVQKRHHTRLFCMDRNERVGKSGNIPAGTTVDTKITHPSEFDFYLCSHAGIQVRDQRKMAELNESPSCALSVSAWFDGGKAFINALYLQGTSRPSHYHVLWDDNHFSSDELQVLTYQLCHTYVRCTRSVSIPAPAYYAHLVAFRARYHLVDKEHD 911

[Close]

BLAST of AGO-2 vs. Ensembl Medaka
Match: ago4 (protein argonaute-4 [Source:NCBI gene;Acc:101167465])

HSP 1 Score: 1229.54 bits (3180), Expect = 0.000e+0
Identity = 593/861 (68.87%), Postives = 690/861 (80.14%), Query Frame = 1

Query:  277 FQPPSRPDQGTDGRTIQLKANHFEIVMPKGFLHHYDITITPEKCPRRVNRDIIQAMVNNMHYQKYFYNQKPVFDGRRNMYTREPLSIGKEKLELEVILPGEGKDRVFKVCLKHVSEVSLFALEEALQGRRQTIPAETVTALDVIMRHLPSMTYTPVGRSFFHNTGDYDNPLGGGREVWFGFHQSVRPSQWKMMLNIDVSATAFYKEQSVINFMFEVLEIDK--DLKRPLTDSQRVKFTKEIKGLKVEINHCGPIKRKYRVCNVTRRSAQSQTFPLQSEQGQTIECTVTKYFQDRYGMKLQHPHLPCLQVGQEQKHTYLPLEVCNIVSGQRCIKKLTDMQTSTMIKATARSAPDREKEINNLVRRSNF--NADPHLQIFGVSVNTRMADIQGRVIPAPKIQYGGRT-----------KAQATPQQGVWDMRGKQFFSGIEIKVWAIACFAPQRTVREDSLRTFTQQLQKISNDAGMPIVGQPCFCKYATGQDQVEPMFRYLKNSFSGLQLIVVVLPGKTPVYAEVKRVGDIIFGLATQCVQAKNVNKPSPQTLSNLCLKINVKLGGINSILVPSVRPAVFKEPVIFLGADFTHPPAGDKTKPSIAAVVGSMDAHPSRYAATVSVQPHRQ----------ETIQDLAAMVKELLIQFYKSTRFKPTRIIYYRDGVSEGQFLNVLNHELKAIREACIKLEMSYQPGITFVVVQKRHHTRLFCSDKKDQMGRSGNIPAGTTVDQIITHPTEFDFYLCSHAGIQGTSRPSHYHVLWDDNRFSADEIQTLTYQLCHTYVRCTRSVSIPAPAYYAHLVAFRARYHLVEKELDSGEGSQKSGNSDERNPTAMMRAVTVHSETLKVMYFA 2784
            FQPP RP  GT G+ I+L ANHF++ +PK  ++HYDI I PEK PRRVNR+++  MV +   Q  F +++P +DG+RNMYT  PL IG+++++LEV LPGEGKD+ FKV L+ VS VSL  L EAL G    +P ++V ALDVI RHLPSM YTPVGRSFF     Y +PLGGGREVWFGFHQSVRP+ W MMLNIDVSATAFY+ Q VI FM EVL+I    +  +PLTDSQRVKFTKEI+GLKVE+ HCG +KRKYRVCNVTRR A  QTFPLQ E GQ +ECTV +YF+ +Y ++L++PHLPCLQVGQEQKHTYLPLEVCNIV+GQRCIKKLTD QTSTMIKATARSAPDR++EI+ LV+ ++     DP+L+ FG+ V+  M ++ GRV+PAP +QYGGR            K  ATP QGVWDMRGKQF++GIEIKVWA+ACFAPQ+  RED L++FT QL+KIS DAGMPI GQPCFCKYA G D VEPMF++LK S+ GLQLIVV+LPGKTPVYAEVKRVGD + G+ATQCVQ KNV K SPQTLSNLCLKIN KLGGIN++LVP  RP+VF++PVIFLGAD THPPAGD  KPSIAAVVGSMD HPSRY ATV VQ  RQ          E IQDL  MV+ELLIQFYKSTRFKPTRIIYYR GVSEGQ   V   EL AIR+ACI LE  Y+PGIT++VVQKRHHTRLFCSDK +++G+SGN+PAGTTVD  ITHP+EFDFYLCSHAGIQGTSRPSHYHVLWDDN F+ADE+Q LTYQLCHTYVRCTRSVSIPAPAYYA LVAFRARYHLV+K+ DS EGS  SG S+ R+P A+ +AV +H +T   MYFA
Sbjct:   88 FQPPRRPGLGTVGKPIRLLANHFQVQIPKIDVYHYDIDIKPEKRPRRVNREVVDTMVRHFKMQ-IFGDRQPGYDGKRNMYTAHPLPIGRDRVDLEVTLPGEGKDQTFKVSLQWVSVVSLQMLLEALSGHLNEVPEDSVQALDVITRHLPSMRYTPVGRSFFSPPEGYYHPLGGGREVWFGFHQSVRPAMWNMMLNIDVSATAFYRAQPVIEFMCEVLDIQNINEQTKPLTDSQRVKFTKEIRGLKVEVTHCGQMKRKYRVCNVTRRPASHQTFPLQLENGQAMECTVAQYFKQKYNLQLKYPHLPCLQVGQEQKHTYLPLEVCNIVAGQRCIKKLTDNQTSTMIKATARSAPDRQEEISRLVKSNSMVGGPDPYLKEFGIVVHNDMTEVTGRVLPAPMLQYGGRVSTDTGRDCGRNKTVATPNQGVWDMRGKQFYAGIEIKVWAVACFAPQKQCREDLLKSFTDQLRKISKDAGMPIQGQPCFCKYAQGADSVEPMFKHLKMSYVGLQLIVVILPGKTPVYAEVKRVGDTLLGMATQCVQVKNVVKTSPQTLSNLCLKINAKLGGINNVLVPHQRPSVFQQPVIFLGADVTHPPAGDGKKPSIAAVVGSMDGHPSRYCATVRVQTSRQDMSQEQLFSQEVIQDLTNMVRELLIQFYKSTRFKPTRIIYYRGGVSEGQMKQVAWPELIAIRKACISLEEDYRPGITYIVVQKRHHTRLFCSDKAERVGKSGNVPAGTTVDSTITHPSEFDFYLCSHAGIQGTSRPSHYHVLWDDNCFTADELQLLTYQLCHTYVRCTRSVSIPAPAYYARLVAFRARYHLVDKDHDSAEGSHVSGQSNGRDPQALAKAVQIHYDTQHTMYFA 947

[Close]

BLAST of AGO-2 vs. Ensembl Medaka
Match: ENSORLT00000011404.2 (protein argonaute-3 [Source:NCBI gene;Acc:101165653])

HSP 1 Score: 1226.08 bits (3171), Expect = 0.000e+0
Identity = 588/847 (69.42%), Postives = 687/847 (81.11%), Query Frame = 1

Query:  277 FQPPSRPDQGTDGRTIQLKANHFEIVMPKGFLHHYDITITPEKCPRRVNRDIIQAMVNNMHYQKYFYNQKPVFDGRRNMYTREPLSIGKEKLELEVILPGEG-KDRVFKVCLKHVSEVSLFALEEALQGRRQTIPAET--------VTALDVIMRHLPSMTYTPVGRSFFHNTGDYDNPLGGGREVWFGFHQSVRPSQWKMMLNIDVSATAFYKEQSVINFMFEVLEIDK--DLKRPLTDSQRVKFTKEIKGLKVEINHCGPIKRKYRVCNVTRRSAQSQTFPLQSEQGQTIECTVTKYFQDRYGMKLQHPHLPCLQVGQEQKHTYLPLEVCNIVSGQRCIKKLTDMQTSTMIKATARSAPDREKEINNLVRRSNFNADPHLQIFGVSVNTRMADIQGRVIPAPKIQYGGRTKAQATPQQGVWDMRGKQFFSGIEIKVWAIACFAPQRTVREDSLRTFTQQLQKISNDAGMPIVGQPCFCKYATGQDQVEPMFRYLKNSFSGLQLIVVVLPGKTPVYAEVKRVGDIIFGLATQCVQAKNVNKPSPQTLSNLCLKINVKLGGINSILVPSVRPAVFKEPVIFLGADFTHPPAGDKTKPSIAAVVGSMDAHPSRYAATVSVQPHRQETIQDLAAMVKELLIQFYKSTRFKPTRIIYYRDGVSEGQFLNVLNHELKAIREACIKLEMSYQPGITFVVVQKRHHTRLFCSDKKDQMGRSGNIPAGTTVDQIITHPTEFDFYLCSHAGIQGTSRPSHYHVLWDDNRFSADEIQTLTYQLCHTYVRCTRSVSIPAPAYYAHLVAFRARYHLVEKELDSGEGSQKSGNSDERNPTAMMRAVTVHSETLKVMYFA 2784
            F  P RP  GT G+ I+L AN F++ +PK  ++ Y++ I P+KCPRRVNR+++ +MV +      F ++ PV+DG++N+YT  PL +    ++L+V LPGEG KDR FKV LK VS VS   L + L+GR    P +         V A+DV++RHLPSM YTPVGRSFF +  D D  LGGGREVWFGFHQSVRP+ WKMMLNIDVSATAFYK QSVI FM EVL+I    +  RPL DS RVKFTKEIKGLKVE+ HCG ++RKYRVCNVTRR A  QTFPLQ E GQT+E TV +YF+++Y ++L++PHLPCLQVGQEQKHTYLPLEVCNIV GQRCIKKLTD QTS MIKATARSAPDR++EI+ LVR +N+ ADP +Q F   +   MA + GRV+PAP +QYGGR +  ATP  GVWDMRGKQF +G+EIKVWAIACFA QR  RE+ L++FT QL+KIS DAGMPI GQPCFCKYA G D VEPMFR+LKN+++GLQLI+V+LPGKTPVYAEVKRVGD + G+ATQCVQ KNV K SPQTLSNLCLKINVKLGGIN+ILVP  RP+VF++P+IFLGAD THPPAGD  KPSIAAVVGSMDAHPSRY ATV +Q  RQE IQDLA+MV+ELLIQFYKSTR+KPTRII+YRDGVSEGQF  VL +EL AIREACI LE  YQPGITF+VVQKRHHTRLFC+D+ +++GRSGNIPAGTTVD  ITHP EFDFYLCSHAGIQGTSRPSHYH+LWDDN F+ADE Q LTYQLCHTYVRCTRSVSIPAPAYYAHLVAFRARYHLV+KE DS EGS  SG S+ R+P A+ +AV +H +TL+ MYFA
Sbjct:   15 FSLPQRPGYGTIGKAIKLLANCFQVDIPKLDVYLYEVDIKPDKCPRRVNREVVDSMVQHFKV-TIFGDRLPVYDGKKNLYTASPLPVASGGVDLDVTLPGEGGKDRPFKVSLKFVSLVSWHLLHDILKGRSTPEPVDLDKPLSTNPVHAVDVVLRHLPSMKYTPVGRSFFSSPKDNDYTLGGGREVWFGFHQSVRPAMWKMMLNIDVSATAFYKAQSVIQFMCEVLDIHNIDEQPRPLADSHRVKFTKEIKGLKVEVTHCGTMRRKYRVCNVTRRPASLQTFPLQLENGQTVERTVAQYFREKYNLQLKYPHLPCLQVGQEQKHTYLPLEVCNIVVGQRCIKKLTDNQTSIMIKATARSAPDRQEEISRLVRNANYGADPFVQEFQFRLCDEMAQVTGRVLPAPMLQYGGRNRTVATPSHGVWDMRGKQFHTGVEIKVWAIACFATQRQCREEILKSFTDQLRKISKDAGMPIQGQPCFCKYAQGADSVEPMFRHLKNTYTGLQLIIVILPGKTPVYAEVKRVGDTLLGMATQCVQMKNVVKTSPQTLSNLCLKINVKLGGINNILVPHQRPSVFQQPIIFLGADVTHPPAGDGKKPSIAAVVGSMDAHPSRYCATVRIQKPRQEIIQDLASMVRELLIQFYKSTRYKPTRIIFYRDGVSEGQFRQVLYYELLAIREACISLEKEYQPGITFIVVQKRHHTRLFCADRNERVGRSGNIPAGTTVDTDITHPYEFDFYLCSHAGIQGTSRPSHYHILWDDNCFTADEFQLLTYQLCHTYVRCTRSVSIPAPAYYAHLVAFRARYHLVDKEHDSAEGSHISGQSNGRDPQALAKAVQIHHDTLRTMYFA 860

[Close]

BLAST of AGO-2 vs. Planmine SMEST
Match: SMESG000047591.1 (SMESG000047591.1)

HSP 1 Score: 1885.92 bits (4884), Expect = 0.000e+0
Identity = 926/928 (99.78%), Postives = 927/928 (99.89%), Query Frame = 1

Query:    1 MLGGTYFTPPTYLFXXXXXXXXXXAILGLAATPNGNQTMNPLGAPGQPPNTSVPAIIGSTQLSSNISSGPSPPQLPTXXXXXXXXXXXXXVYFQPPSRPDQGTDGRTIQLKANHFEIVMPKGFLHHYDITITPEKCPRRVNRDIIQAMVNNMHYQKYFYNQKPVFDGRRNMYTREPLSIGKEKLELEVILPGEGKDRVFKVCLKHVSEVSLFALEEALQGRRQTIPAETVTALDVIMRHLPSMTYTPVGRSFFHNTGDYDNPLGGGREVWFGFHQSVRPSQWKMMLNIDVSATAFYKEQSVINFMFEVLEIDKDLKRPLTDSQRVKFTKEIKGLKVEINHCGPIKRKYRVCNVTRRSAQSQTFPLQSEQGQTIECTVTKYFQDRYGMKLQHPHLPCLQVGQEQKHTYLPLEVCNIVSGQRCIKKLTDMQTSTMIKATARSAPDREKEINNLVRRSNFNADPHLQIFGVSVNTRMADIQGRVIPAPKIQYGGRTKAQATPQQGVWDMRGKQFFSGIEIKVWAIACFAPQRTVREDSLRTFTQQLQKISNDAGMPIVGQPCFCKYATGQDQVEPMFRYLKNSFSGLQLIVVVLPGKTPVYAEVKRVGDIIFGLATQCVQAKNVNKPSPQTLSNLCLKINVKLGGINSILVPSVRPAVFKEPVIFLGADFTHPPAGDKTKPSIAAVVGSMDAHPSRYAATVSVQPHRQETIQDLAAMVKELLIQFYKSTRFKPTRIIYYRDGVSEGQFLNVLNHELKAIREACIKLEMSYQPGITFVVVQKRHHTRLFCSDKKDQMGRSGNIPAGTTVDQIITHPTEFDFYLCSHAGIQGTSRPSHYHVLWDDNRFSADEIQTLTYQLCHTYVRCTRSVSIPAPAYYAHLVAFRARYHLVEKELDSGEGSQKSGNSDERNPTAMMRAVTVHSETLKVMYFA 2784
            MLGGTYFTPPTYLFNSNGNNENNSAILGLAATPNGNQTMNPLGAPGQPPNTSVPAIIGSTQLSSNISSGPSPPQLPTGSNSQYSSSGNGSVYFQPPSRPDQGTDGRTIQLKANHFEIVMPKGFLHHYDITITPEKCPRRVNRDIIQAMVNNMHYQKYFYNQKPVFDGRRNMYTREPLSIGKEKLELEVILPGEGKDRVFKVCLKHVSEVSLFALEEALQGRRQTIPAETVTALDVIMRHLPSMTYTPVGRSFFHNTGDYDNPLGGGREVWFGFHQSVRPSQWKMMLNIDVSATAFYKEQSVINFMFEVLEIDKD KRPLTDSQRVKFTKEIKGLKVEINHCGPIKRKYRVCNVTRRSAQSQTFPLQSEQGQTIECTVTKYFQDRYGMKLQHPHLPCLQVGQEQKHTYLPLEVCNIVSGQRCIKKLTDMQTSTMIKATARSAPDREKEINNLVRRSNFNADPHLQIFGVSVNTRMADIQGRVIPAPKIQYGGRTKAQATPQQGVWDMRGKQFFSGIEIKVWAIACFAPQRTVREDSLRTFTQQLQKISNDAGMPIVGQPCFCKYATGQDQVEPMFRYLKNSF+GLQLIVVVLPGKTPVYAEVKRVGDIIFGLATQCVQAKNVNKPSPQTLSNLCLKINVKLGGINSILVPSVRPAVFKEPVIFLGADFTHPPAGDKTKPSIAAVVGSMDAHPSRYAATVSVQPHRQETIQDLAAMVKELLIQFYKSTRFKPTRIIYYRDGVSEGQFLNVLNHELKAIREACIKLEMSYQPGITFVVVQKRHHTRLFCSDKKDQMGRSGNIPAGTTVDQIITHPTEFDFYLCSHAGIQGTSRPSHYHVLWDDNRFSADEIQTLTYQLCHTYVRCTRSVSIPAPAYYAHLVAFRARYHLVEKELDSGEGSQKSGNSDERNPTAMMRAVTVHSETLKVMYFA
Sbjct:    1 MLGGTYFTPPTYLFNSNGNNENNSAILGLAATPNGNQTMNPLGAPGQPPNTSVPAIIGSTQLSSNISSGPSPPQLPTGSNSQYSSSGNGSVYFQPPSRPDQGTDGRTIQLKANHFEIVMPKGFLHHYDITITPEKCPRRVNRDIIQAMVNNMHYQKYFYNQKPVFDGRRNMYTREPLSIGKEKLELEVILPGEGKDRVFKVCLKHVSEVSLFALEEALQGRRQTIPAETVTALDVIMRHLPSMTYTPVGRSFFHNTGDYDNPLGGGREVWFGFHQSVRPSQWKMMLNIDVSATAFYKEQSVINFMFEVLEIDKDQKRPLTDSQRVKFTKEIKGLKVEINHCGPIKRKYRVCNVTRRSAQSQTFPLQSEQGQTIECTVTKYFQDRYGMKLQHPHLPCLQVGQEQKHTYLPLEVCNIVSGQRCIKKLTDMQTSTMIKATARSAPDREKEINNLVRRSNFNADPHLQIFGVSVNTRMADIQGRVIPAPKIQYGGRTKAQATPQQGVWDMRGKQFFSGIEIKVWAIACFAPQRTVREDSLRTFTQQLQKISNDAGMPIVGQPCFCKYATGQDQVEPMFRYLKNSFTGLQLIVVVLPGKTPVYAEVKRVGDIIFGLATQCVQAKNVNKPSPQTLSNLCLKINVKLGGINSILVPSVRPAVFKEPVIFLGADFTHPPAGDKTKPSIAAVVGSMDAHPSRYAATVSVQPHRQETIQDLAAMVKELLIQFYKSTRFKPTRIIYYRDGVSEGQFLNVLNHELKAIREACIKLEMSYQPGITFVVVQKRHHTRLFCSDKKDQMGRSGNIPAGTTVDQIITHPTEFDFYLCSHAGIQGTSRPSHYHVLWDDNRFSADEIQTLTYQLCHTYVRCTRSVSIPAPAYYAHLVAFRARYHLVEKELDSGEGSQKSGNSDERNPTAMMRAVTVHSETLKVMYFA 928

[Close]

BLAST of AGO-2 vs. Planmine SMEST
Match: SMESG000050994.1 (SMESG000050994.1)

HSP 1 Score: 424.861 bits (1091), Expect = 6.286e-130
Identity = 284/840 (33.81%), Postives = 442/840 (52.62%), Query Frame = 1

Query:  286 PSRPDQG-TDGRTIQLKANHFEIVMPKGFLHHYDITITPEKC-----------------PRRVNRDIIQAMVNNMHYQKYFYNQKPVFDGRRNMYTRE--PLSIGKEKLELEVILPGEGKDRVFKVCLKHVSEVSLFALEEALQ---GRRQTIPAETVTALDVIMRH--LPSMTYTPVGRSFFHNTGDYDNPLGGGREVWF-GFHQSVRPSQWKMMLNIDVSATAFYKEQSVINFMFEVLEIDKDLKRPLTDSQRVKFTKEIKGLKVEINHCG-----PIKRKYRVCNVTRRSAQSQTFPLQSEQGQTIECTVTKYFQDRYGMKLQHPHLPCLQVGQEQKHTYLPLEVCNIVSGQRCIKKLTDMQTSTMIKATARSAPDREKEINNLVRRSNFN--ADPHLQIFGVSVNTRMADIQGRVIPAPKIQYGGRTKAQATP-QQGVWDMRGKQFFSGIEIKV-WAIACFAPQRTVREDS--LRTFTQQLQKISNDAGMPIVGQPCF--CKYATGQDQVEPMFRYLKNSFSGLQLIVVVLPGKTPVYAEVKRVGDIIFGLATQCVQAKNVNKPS--PQTLSNLCLKINVKLGGINSILVPSVRPAVF---KEPVIFLGADFTHPPA--GDKTKPSIAAVVGSMDAHPSRYAATVSVQPHRQE-----TIQDLAAMVKELLIQFYKSTR-FKPTRIIYYRDGVSEGQFLNVLNHELKAIREACIKLEMSYQPGITFVVVQKRHHTRLFCSDKKDQMGRSGNIPAGTTVDQIITHPTEFDFYLCSHAGIQGTSRPSHYHVLWDDNRFSADEIQTLTYQLCHTYVRCTRSVSIPAPAYYAHLVAFRAR 2649
            PSRPD G   GR I+L  N  ++ +    +  YDI +T  +                  P+   +D+I+ +V  +  +       PVFDG R ++T +  P + G  K+        E     F +      ++ L  L   +Q   GR   +P E + ALD I R   L     T  GR+ F        PL  G  +   G+  ++RP  WK+  N D +    ++  ++ +++ ++++ ++     L  +     T+++K L+V+ NH          RKY +   + +SA+ +      E+  TIE    +YFQ  Y +KL++P+LP ++     K T++P+E+  ++  QR I+    +    +IK  A  A DR  ++N+ +         D  LQ + + ++ ++  +  RV+  P+  +GG+   +  P + G WD+R K+F    +  V WA+     +R  + +   L     +L   +N+ G+ + G   F    Y   +       R  +     L L+V V+      Y EVK+ GD++FG+ TQC++   +N+     Q L N+ LK+N KLGG+N  L P +R  +F   K+  +  G D THP +   D +K S+AA+VGS+D + + Y+A +  Q  ++E      + ++  MV  LL+ FYK+ +  KP R+I+YRDGVSEGQF  V  HE+ AI+ AC KLE  YQP IT++VVQKRH  R F  ++KD +GRSGN+P+GT VD+ ITH  EFDFYLCSH GIQGTS+P+HYHVL+D+N + +DE+Q+ TY LCH Y RCTRSVS PAP YYAHL AFR R
Sbjct:  401 PSRPDDGGKKGRPIKLIINCCDVKINPMKIFMYDIELTKAEVIVAEKDKTEKKKSRDVTPKMKKKDVIRNIVKELLQKA---EGMPVFDGGRIIFTNKLLPYNDGTCKITHNFNYESENVTCHFNIQRVKEEDIELGNLNNYIQSKKGRSDDMPQEALRALDTIFREMFLNKNLITIGGRAIFDPKTS--TPLRCGPYILMEGYATTIRPHMWKVRFNFDKTQVVCHEAINLYDYISKIMDPNR-----LNPNTIRNLTRKLKTLRVQANHLKNADGKAYSRKYTIFGFSNKSAREEKI---VEKNLTIE----QYFQKEYNIKLKYPNLPMVKTS-PNKPTFVPIELLTMLPNQRVIESDGKI-VQEVIKFAAIPAADRLYKLNSAMSSLQIGNRGDKFLQNYKIEIDPKLIGVDARVLDGPEGIFGGQ---RTEPLRGGKWDIRNKKFIKPYDKLVNWALFAVGTERDYQRNDKPLYDIEDKLPGAANNVGIRMGGSFYFSYVPYQNIEKVATDTIRNSEKEKKKLDLLVFVVINDED-YKEVKKFGDVLFGIVTQCMKYATLNRQKFLDQYLGNIMLKVNGKLGGVNWELSP-IRNRLFTPIKDSFMVFGIDVTHPASTRNDLSK-SVAAMVGSLDNNATMYSALIRQQLSKKERAIIEIVMEMEDMVYNLLMTFYKANKQLKPKRLIFYRDGVSEGQFDIVFKHEIIAIQSACQKLEKDYQPPITYIVVQKRHKIRFFPQNEKDGVGRSGNVPSGTVVDKDITHCREFDFYLCSHEGIQGTSKPAHYHVLFDENNWGSDELQSFTYFLCHIYARCTRSVSYPAPTYYAHLAAFRGR 1215

[Close]

BLAST of AGO-2 vs. Planmine SMEST
Match: SMESG000051000.1 (SMESG000051000.1)

HSP 1 Score: 337.421 bits (864), Expect = 3.005e-100
Identity = 241/820 (29.39%), Postives = 401/820 (48.90%), Query Frame = 1

Query:  286 PSRPDQG-TDGRTIQLKANHFEIVMPKGFLHHYDITITPEKCPRRVN----------RDIIQAMVNNMHYQKYFYNQKPVFDGRRNMYTREPLSIGKEKLELEVILPGEGKDRVFKVCLKHVSEVSLFALEEAL----QGRRQTIPAETVTALDVIMRH-LPSMTYTPVGRSFFHNTGDYDNPLGGG-REVWFGFHQSVRPSQWKMMLNIDVSATAFYKEQSVINFMFEVLEIDKDLKRPLTDSQRVKFTKEIKGLKVEINHCGPIK-----RKYRVCNVTRRSAQSQTFPLQSEQGQTIECTVTKYFQDRYGMKLQHPHLPCLQVGQEQKHTYLPLEVCNIVSGQRCIKKLTDMQTSTMIKATARSAPDREKEIN-NLVRRSNFNADPHLQIFGVSVNTRMADIQGRVIPAPKIQYGGRTKAQATPQQGVWDMRGKQFFSGIEIKVWAIACFAPQRTV-REDSLRTFTQQLQKISNDAGMPIVGQPCFCKYATGQDQVEPMFRYLKNSFSGLQLIVVVLPGKTPVYAEVKRVGDIIFGLATQCVQAKNV--NKPSPQTLSNLCLKINVKLGGINSILVPSVRPAVFKEPVIFLGADFTHPPAGDKTKPSIAAVVGSMDAHPSRYAATVSVQPHRQ-----ETIQDLAAMVKELLIQFYKSTRFK-PTRIIYYRDGVSEGQFLNVLNHELKAIREACIKLEMSYQPGITFVVVQKRHHTRLFCSDKKDQMGRSGNIPAGTTVDQIITHPTEFDFYLCSHAGIQGTSRPSHYHVLWDDNRFSADEIQTLTYQLCHTYVRCTRSVSIPAPAYYAHLVAFRAR 2649
            P RPD+G T GR I L  N F + +    +  YDI +   +     N          +DI + +V+     K      P+FDG R ++  + L   +   +L  I   E ++    + L+ V+      L +      +GR   IP ET+  LD+I+R  L       +G     N      PL      +  G+  ++RP    +  N+D +    ++  ++ +++ +V  ++           +      I  +KV+ +H    +     R + V  V +++A ++         + +  +V +YF   +G+ L++P L  ++     K    P E+  I+  Q+ +    ++    +IK +A    +R   +  ++V    F  + +LQ + +++  +M +++GR++  P   +G + +     +  + + + K  F    IK WA+  F  +R    E+ L     +L K +    + I+    FC      D ++     +K     L L+VVV+      Y  VK +GDI  G+ TQC+  +N+   K   Q + NL LK+N KLGG+N   + ++  A  K   +  G D THP   D    S+AAVVGS++   + Y+A +  Q  +      ET+ ++  MV  L+  FY   + K P  +I+YRDGVSEGQF  V NHE+ AI+ AC K + +Y+P IT+++VQKRH+ R      +D +GR  N+  G  +D  ITH  EFDFYLCSH GIQGTS+P HY+V+ D+NR++++++Q  TY LC+   RCTRS+S PAP +YAHL AFR R
Sbjct:  120 PERPDKGGTKGRQIPLIVNCFNMTVKSTKIFMYDIELLKAELVLENNVRDFTNKIKRKDIFRDVVSQFLKDKCGL---PIFDGGRIIFNNQLLPYTETINKLNFIYNYENQNINCHLNLQLVNSDIDLDLIDDYIHSGKGRSNNIPQETIRVLDIIIREMLLDCDLILIGNKGLFNPRT-SKPLDRDPYTILSGYFSTIRPHMSNIRFNLDTTQIVCHQAINMKDYIQKVFTLNN-----FNIQNKKHINSRIYNIKVKASHYKNDQGENYTRIFTVKGVYQKNAHNEII-------ENLGKSVNEYFLSTHGINLKYPELLLIETTNYNK---FPAELLTILPNQKVMGNDPNI-VREVIKHSAIPCTERFDNLKKSVVAFKGFRNNKYLQSYNITIIPQMINVKGRILDEPTALFGDKEEKLPKSKFNIMNKKFKDPFHD-PIK-WALFAFGERREYGNENELYAIEIELPKAAIKVNVKILKDNTFC--YVSNDDIKKSIEKIK---EDLDLLVVVVRNDVE-YKLVKDIGDIELGIVTQCICYENLCRQKNLSQYMGNLMLKVNAKLGGVNW-EIKNIEYAPIKGLFMVFGVDVTHPSNNDGLSKSVAAVVGSINKTATIYSAVIKKQLSKDGKDAVETVVEMEDMVHRLIKVFYDLNQSKLPDHLIFYRDGVSEGQFEIVFNHEIAAIQYACEKFKKNYKPKITYIIVQKRHNIRFCPITLEDSVGRCKNVLPGVVIDNDITHSREFDFYLCSHEGIQGTSKPVHYYVILDENRWNSNDLQEFTYFLCYVCFRCTRSISYPAPTHYAHLAAFRGR 910

[Close]

BLAST of AGO-2 vs. Planmine SMEST
Match: SMESG000081970.1 (SMESG000081970.1)

HSP 1 Score: 169.474 bits (428), Expect = 1.053e-42
Identity = 160/647 (24.73%), Postives = 285/647 (44.05%), Query Frame = 1

Query:  802 EVWFGFHQSVRPSQWKMMLNIDVSATAFYKEQSVINFMFEVLEIDKDLKRPLTDSQRVKFTKEIKGLKVEINHCGPIKRKYRVCNVTRRSAQSQTFPLQSEQGQTIECTVTKYFQDRYGMKLQHPHLPCLQVGQEQKH----------------TYLPLEVCNIVSGQRCIKKLTDMQTSTMIKATARSAPDREKE-----INNLVRRSNFNADPHLQIFGVSVNTRMADIQGRVIPAPKIQYGGRTKAQATPQQGVWD-MRGKQFFSGIEIKVWAIACFAPQRTVREDSLRTFTQQLQKISNDAGMPIVGQPCFCKYATGQDQVEPMFRYLK-NSFSGLQLIVVVLPG-KTPVYAEVKRVGDIIFGLATQCVQAKNVNKPSPQTLS---NLCLKINVKLGG-INSILVPSVRPAVFKEPVIFLGADFTHPPAGDKTKPSIAAVVGSMDAHPSRYAATVSVQPHRQETIQDLAAMVKELLIQFYKSTRFKPTRIIYYRDGVSEGQFLNVLNHELKAIREACIKLEMSYQPGITFVVVQKRHHTRLFCSDKKDQMGRSGNIPAGTTVDQIITHPTEFDFYLCSHAGIQGTSRPSHYHVLWDDNRFSADEIQTLTYQLCHTYVRCTRSVSIPAPAYYAHLVAFRARYHL 2658
            E+W G+  S++     ++L  DVS     +  SV + M E+        + + +  +++ T  I  L  +I       R YR+ ++         F    E+      +   YF++ YG++++    P +      +                  YL  E+C +      + K  D +    +    R  P +  E     ++N+   S   A   L  +G+++     +I    +    I +G      A  Q      +   +   GI I+ W +   +P+  + + +     Q L   S   G+ + G+P   +     D+ E   + LK N   G+QL+V +L   +   Y  +K+   +   + +Q V A+ + K  P+  S   N+ L+IN KLGG + ++ +P  +        + +G D  H   G     S+ AVVGS +A  +R+ +   +Q   +E +  L + +  LL  +++   F P  I  YRDGVS+GQ   V   E++   +        Y+P + + VVQKR +TRL+ SD K++ G+  N   GT VD  +T    +DF+L S +  QGT  P+HY VL D+++++  ++Q + Y+ CH Y     +V +PAP  YAH +A+    +L
Sbjct:  349 EIWPGYVTSIQNFDGGLLLQCDVSHKVI-RNDSVYDIMMEI-------NKTVNNKGQMQ-TAAINQLLGQIVLTPHNNRNYRITDIDWAKNCLSEFDKGGEK-----ISYRDYFKNTYGLQIRDLEQPMIVSKSNSRSGKNRGPKGSKEVDGGLVYLIPELCMLTGLTDDMIK--DFRLMRELHEHCRVTPKKRHEALLEFVDNIY--SCEEAKKLLGYWGITIEKDTVNINACKMNPEMIYFGNEASVSAGEQAEFKQALAHNKVIGGIRIENWIL--ISPKSLLTKAN--GLLQALMSKSPRVGV-MFGKPKIVE--MNNDRTEEYLKELKRNVAPGVQLVVTILSAVREDRYNAIKKFCYVDCPVPSQVVLAQTL-KEGPKLNSVAVNIALQINAKLGGELWAVKIPIKK-------FMVVGLDVWHDTKGRSR--SVGAVVGSTNALCTRWFSKSHLQEQDKEIMYVLQSCMLSLLKAYFEENNFLPETIFMYRDGVSDGQLGYVQKTEIEQFFKVFESFSADYKPNMVYNVVQKRINTRLYVSDPKNK-GQINNPNPGTIVDHTVTRANLYDFFLVSQSVRQGTVTPTHYVVLCDNSKYTPHQVQLMAYKTCHIYYNWPGTVRVPAPCMYAHKLAYMVGQNL 959

[Close]

BLAST of AGO-2 vs. Planmine SMEST
Match: SMESG000069984.1 (SMESG000069984.1)

HSP 1 Score: 118.242 bits (295), Expect = 9.802e-27
Identity = 104/355 (29.30%), Postives = 159/355 (44.79%), Query Frame = 1

Query: 1621 QQLQKISNDAGMPIVGQPCFCKYATGQDQVEPMFRYLKNSFSGLQLIVVVLPGKTPVYAEVKRVGDIIFGLATQCVQAKN----VNKPSPQTLSNLCLKINVKLGGINSILVPSVRPAVFKEPVIFLGADFTHPPAGDKTKPSIAAVVGSMDAHPSRYAATVSVQPHRQETIQDLAAMVKELLIQFYKSTRFKPTRIIYYRDGVSEGQFLNVLNHELKAIR---EACIKLEMSYQPGITFVVVQKRHHTRLFCSDKKDQMGRSGNIPAGTTVDQIITHPTEFDFYLCSHAGIQGTSRPSHYHVLWDDNRFSA---------DEIQTLTYQLCHTYVRCTRSVSIPAPAYYAHLVA 2637
            Q+L+ +  DA    VG+   C    G + VE        S SG   + +V      VYA+VK    +  GL TQCV  +N     +K      S   ++I  K G     +   +RP       + +G D  H  +   +K SI A V S+++  ++Y + V+    RQE  + L       L  F K     P RI+ +RDGV + Q     N E+ A++   E   K      P I +V+V+KR  T+LF         R  N   GT VD+ I  P  ++F+L S    +GT+ P++Y+VL D    +          +E+Q +TY L H Y     ++ +P P +YAH +A
Sbjct:  481 QELRNMRIDAR---VGKVNTC----GPNDVERCLNDAARSGSGCAKMALVFVPDDRVYAKVKSF-TMSTGLLTQCVTTRNGTNRNDKRRKVVSSKTVMQIFAKFGYDPWTVEIKLRPT------MIVGMDTYHNKS---SKKSIQASVFSINSTFTQYMSFVNSPKGRQEFHETLGKNFNLALEDFKKRYDILPQRILVFRDGVGDNQLQFTKNFEVDAMKPLIENIYKGNGFPVPQIIYVIVKKRVGTKLF--------NRGNNPNPGTVVDKEIVKPNFYEFFLVSQRTTKGTATPTNYNVLEDTRLLTKKGTMDPMAPNELQKITYALTHLYFNWMGTIRVPVPVHYAHRLA 810

The following BLAST results are available for this feature:

BLAST of AGO-2 vs. Ensembl Human
BLAST of AGO-2 vs. Ensembl Celegans
BLAST of AGO-2 vs. Ensembl Fly
BLAST of AGO-2 vs. Ensembl Zebrafish
BLAST of AGO-2 vs. Ensembl Xenopus
BLAST of AGO-2 vs. Ensembl Mouse
BLAST of AGO-2 vs. UniProt/SwissProt
BLAST of AGO-2 vs. TrEMBL
BLAST of AGO-2 vs. Ensembl Cavefish
BLAST of AGO-2 vs. Ensembl Sea Lamprey
BLAST of AGO-2 vs. Ensembl Yeast
BLAST of AGO-2 vs. Ensembl Nematostella
BLAST of AGO-2 vs. Ensembl Medaka
BLAST of AGO-2 vs. Planmine SMEST

BLAST of AGO-2 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5


Match Name	E-value	Identity	Description
AGO2	0.000e+0	73.87	argonaute RISC catalytic component 2 [Source:HGNC ...	[more]
AGO1	0.000e+0	71.00	argonaute RISC component 1 [Source:HGNC Symbol;Acc...	[more]
AGO3	0.000e+0	70.26	argonaute RISC catalytic component 3 [Source:HGNC ...	[more]
AGO2	0.000e+0	70.29	argonaute RISC catalytic component 2 [Source:HGNC ...	[more]
AGO4	0.000e+0	68.94	argonaute RISC component 4 [Source:HGNC Symbol;Acc...	[more]

BLAST of AGO-2 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 5


Match Name	E-value	Identity	Description
alg-1	0.000e+0	67.85	pep chromosome:WBcel235:X:13949114:13956261:1 gene...	[more]
alg-1	0.000e+0	67.85	pep chromosome:WBcel235:X:13951262:13956261:1 gene...	[more]
alg-2	0.000e+0	66.82	pep chromosome:WBcel235:II:874160:879001:1 gene:WB...	[more]
alg-2	0.000e+0	66.82	pep chromosome:WBcel235:II:873176:878945:1 gene:WB...	[more]
alg-5	0.000e+0	38.49	pep chromosome:WBcel235:I:9989802:9993975:1 gene:W...	[more]

BLAST of AGO-2 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5


Match Name	E-value	Identity	Description
AGO1	0.000e+0	75.41	gene:FBgn0262739 transcript:FBtr0305592	[more]
AGO1	0.000e+0	75.41	gene:FBgn0262739 transcript:FBtr0087612	[more]
AGO1	0.000e+0	75.41	gene:FBgn0262739 transcript:FBtr0087613	[more]
AGO1	0.000e+0	75.41	gene:FBgn0262739 transcript:FBtr0087614	[more]
AGO2	2.593e-96	30.76	gene:FBgn0087035 transcript:FBtr0331933	[more]

BLAST of AGO-2 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5


Match Name	E-value	Identity	Description
ago2	0.000e+0	70.40	argonaute RISC catalytic component 2 [Source:ZFIN;...	[more]
ago1	0.000e+0	69.24	argonaute RISC component 1 [Source:ZFIN;Acc:ZDB-GE...	[more]
ago3b	0.000e+0	69.89	argonaute RISC catalytic component 3b [Source:NCBI...	[more]
ago4	0.000e+0	69.76	argonaute RISC component 4 [Source:ZFIN;Acc:ZDB-GE...	[more]
ago3b	0.000e+0	69.32	argonaute RISC catalytic component 3b [Source:NCBI...	[more]

BLAST of AGO-2 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5


Match Name	E-value	Identity	Description
rbm26	0.000e+0	73.51	RNA binding motif protein 26 [Source:Xenbase;Acc:X...	[more]
rbm26	0.000e+0	73.39	RNA binding motif protein 26 [Source:Xenbase;Acc:X...	[more]
rbm26	0.000e+0	73.04	RNA binding motif protein 26 [Source:Xenbase;Acc:X...	[more]
rbm26	0.000e+0	73.58	RNA binding motif protein 26 [Source:Xenbase;Acc:X...	[more]
rbm26	0.000e+0	72.64	RNA binding motif protein 26 [Source:Xenbase;Acc:X...	[more]

BLAST of AGO-2 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5


Match Name	E-value	Identity	Description
Ago2	0.000e+0	73.87	argonaute RISC catalytic subunit 2 [Source:MGI Sym...	[more]
Ago1	0.000e+0	71.00	argonaute RISC catalytic subunit 1 [Source:MGI Sym...	[more]
Ago3	0.000e+0	70.13	argonaute RISC catalytic subunit 3 [Source:MGI Sym...	[more]
Ago4	0.000e+0	68.59	argonaute RISC catalytic subunit 4 [Source:MGI Sym...	[more]
Ago1	0.000e+0	75.41	argonaute RISC catalytic subunit 1 [Source:MGI Sym...	[more]

BLAST of AGO-2 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5


Match Name	E-value	Identity	Description
sp\|Q9UKV8\|AGO2_HUMAN	0.000e+0	73.87	Protein argonaute-2 OS=Homo sapiens OX=9606 GN=AGO...	[more]
sp\|Q9QZ81\|AGO2_RAT	0.000e+0	73.87	Protein argonaute-2 OS=Rattus norvegicus OX=10116 ...	[more]
sp\|Q8CJG0\|AGO2_MOUSE	0.000e+0	73.87	Protein argonaute-2 OS=Mus musculus OX=10090 GN=Ag...	[more]
sp\|O77503\|AGO2_RABIT	0.000e+0	73.87	Protein argonaute-2 (Fragment) OS=Oryctolagus cuni...	[more]
sp\|Q6QME8\|AGO2_BOVIN	0.000e+0	73.75	Protein argonaute-2 OS=Bos taurus OX=9913 GN=AGO2 ...	[more]

BLAST of AGO-2 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5


Match Name	E-value	Identity	Description
F8TJX6	0.000e+0	100.00	AGO-2 OS=Schmidtea mediterranea OX=79327 PE=2 SV=1	[more]
D5JG45	0.000e+0	99.24	Argonaute-2 (Fragment) OS=Dugesia japonica OX=6161...	[more]
A0A4S2LHY1	0.000e+0	85.71	Uncharacterized protein OS=Opisthorchis felineus O...	[more]
A0A074ZUU8	0.000e+0	85.71	Uncharacterized protein OS=Opisthorchis viverrini ...	[more]
A0A3R7D5K5	0.000e+0	85.71	Protein argonaute-2 OS=Clonorchis sinensis OX=7992...	[more]

BLAST of AGO-2 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5


Match Name	E-value	Identity	Description
ago2	0.000e+0	70.96	argonaute RISC catalytic component 2 [Source:NCBI ...	[more]
ago2	0.000e+0	73.99	argonaute RISC catalytic component 2 [Source:NCBI ...	[more]
ago4	0.000e+0	68.87	protein argonaute-4 [Source:NCBI gene;Acc:10304381...	[more]
ago3b	0.000e+0	70.72	argonaute RISC catalytic component 3b [Source:NCBI...	[more]
ago3a	0.000e+0	70.84	argonaute RISC catalytic component 3a [Source:ZFIN...	[more]

BLAST of AGO-2 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 5


Match Name	E-value	Identity	Description
ENSPMAT00000009610.1	0.000e+0	71.59	pep scaffold:Pmarinus_7.0:GL477777:44890:66775:1 g...	[more]
ago2	1.413e-158	79.86	argonaute RISC catalytic component 2 [Source:ZFIN;...	[more]
ENSPMAT00000009316.1	1.484e-144	65.54	pep scaffold:Pmarinus_7.0:GL484064:2408:13690:1 ge...	[more]
ENSPMAT00000009143.1	3.150e-134	49.63	pep scaffold:Pmarinus_7.0:GL477723:307292:327713:-...	[more]
ENSPMAT00000009140.1	1.831e-130	49.63	pep scaffold:Pmarinus_7.0:GL477723:307292:327713:-...	[more]

BLAST of AGO-2 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0


Match Name	E-value	Identity	Description

BLAST of AGO-2 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 5


Match Name	E-value	Identity	Description
EDO46431	0.000e+0	66.31	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO38583	0.000e+0	43.86	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO49931	4.483e-51	24.39	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO34027	6.779e-46	25.67	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO38584	9.457e-18	51.52	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]

BLAST of AGO-2 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5


Match Name	E-value	Identity	Description
AGO2	0.000e+0	73.99	protein argonaute-2 [Source:NCBI gene;Acc:10115610...	[more]
ago1	0.000e+0	71.00	protein argonaute-1 [Source:NCBI gene;Acc:10116948...	[more]
AGO2	0.000e+0	71.75	protein argonaute-2 [Source:NCBI gene;Acc:10115610...	[more]
ago4	0.000e+0	68.87	protein argonaute-4 [Source:NCBI gene;Acc:10116746...	[more]
ENSORLT00000011404.2	0.000e+0	69.42	protein argonaute-3 [Source:NCBI gene;Acc:10116565...	[more]

BLAST of AGO-2 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5


Match Name	E-value	Identity	Description
SMESG000047591.1	0.000e+0	99.78	SMESG000047591.1	[more]
SMESG000050994.1	6.286e-130	33.81	SMESG000050994.1	[more]
SMESG000051000.1	3.005e-100	29.39	SMESG000051000.1	[more]
SMESG000081970.1	1.053e-42	24.73	SMESG000081970.1	[more]
SMESG000069984.1	9.802e-27	29.30	SMESG000069984.1	[more]

Analyses

This transcript is derived from or has results from the following analyses


Analysis Name	Date Performed
Embryonic Stages	2016-07-25
Schmidtea mediterranea smed_20140614 BLASTX Human e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL	2020-05-01
Schmidtea mediterranea Sexual smed_20140614 transcriptome	2016-07-25
Schmidtea mediteranean smed_20140614 Interproscan	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST	2020-05-08

Cross References

External references for this transcript


Database	Accession
SmedGD GBrowse	SMED30014222
GenBank	ADY05336.1

Sequences

The following sequences are available for this feature:

transcript sequence
protein sequence

transcript sequence

>SMED30014222 ID=SMED30014222|Name=AGO-2|organism=Schmidtea mediterranea sexual|type=transcript|length=3040bp
ATGCTTGGTGGAACTTATTTCACCCCTCCAACCTATTTATTCAATTCAAA
TGGGAATAATGAAAATAATAGTGCTATATTGGGTCTTGCTGCAACACCGA
ATGGAAATCAAACTATGAATCCGTTAGGGGCACCAGGTCAACCTCCAAAT
ACAAGTGTTCCTGCTATTATCGGGTCTACTCAATTATCTTCGAATATTTC
ATCAGGTCCATCACCACCCCAATTACCTACTGGTAGTAATTCTCAGTATT
CTTCAAGTGGTAATGGATCCGTATATTTTCAACCACCAAGCAGACCCGAT
CAAGGAACTGATGGAAGAACCATACAACTTAAAGCAAATCATTTTGAAAT
AGTTATGCCAAAAGGGTTTCTTCATCATTATGATATAACTATAACACCGG
AGAAGTGCCCTAGACGTGTTAATCGGGATATTATTCAAGCTATGGTTAAC
AATATGCATTACCAAAAATACTTTTACAACCAGAAACCTGTGTTTGACGG
TAGACGAAATATGTATACACGTGAACCATTATCTATCGGAAAAGAAAAGC
TTGAATTGGAGGTAATTTTACCAGGCGAAGGAAAGGATAGAGTTTTTAAA
GTTTGCCTCAAACATGTGAGCGAAGTGTCACTGTTTGCTCTCGAAGAAGC
TCTTCAAGGACGTCGACAAACCATTCCAGCAGAAACAGTAACTGCTCTGG
ATGTAATAATGCGGCATTTGCCAAGCATGACTTATACTCCTGTTGGGCGT
TCTTTTTTTCACAATACTGGCGATTATGATAATCCTCTAGGAGGTGGCCG
AGAAGTGTGGTTTGGTTTTCATCAAAGTGTCAGACCGTCTCAGTGGAAAA
TGATGCTTAATATTGATGTTTCTGCTACTGCTTTTTACAAGGAACAATCG
GTCATTAATTTTATGTTTGAAGTTCTTGAAATTGACAAAGATCTAAAACG
ACCACTAACTGATAGTCAACGTGTCAAATTTACGAAGGAAATCAAAGGAT
TAAAAGTGGAAATAAACCATTGTGGGCCAATCAAGCGTAAATATCGCGTG
TGTAACGTAACAAGACGTAGTGCTCAATCTCAAACATTCCCCCTTCAGTC
TGAACAAGGTCAGACTATAGAATGCACCGTAACAAAATATTTTCAAGATC
GTTACGGTATGAAATTGCAACATCCTCATTTACCGTGTCTCCAAGTGGGA
CAAGAACAAAAGCATACTTATTTACCTCTAGAAGTGTGTAATATTGTCAG
CGGACAACGTTGTATTAAAAAACTCACAGATATGCAAACATCAACTATGA
TAAAAGCGACAGCAAGATCAGCACCAGACCGAGAGAAAGAAATCAATAAT
TTGGTGCGACGATCTAATTTCAATGCTGATCCACATTTGCAAATATTTGG
AGTTAGTGTCAACACTCGTATGGCTGATATTCAAGGAAGAGTGATTCCAG
CACCAAAAATCCAATATGGTGGGCGTACTAAAGCACAAGCAACTCCCCAA
CAAGGTGTTTGGGATATGAGAGGGAAACAATTCTTTTCTGGTATAGAAAT
CAAAGTATGGGCGATTGCTTGCTTTGCTCCTCAGCGGACAGTGAGAGAAG
ATTCATTGAGGACGTTTACACAGCAATTACAAAAGATCTCAAACGATGCT
GGCATGCCAATTGTAGGTCAACCGTGTTTCTGCAAATATGCAACGGGCCA
AGATCAAGTCGAGCCAATGTTCAGGTATCTGAAGAACAGCTTCAGTGGAC
TGCAACTGATTGTTGTGGTGTTACCTGGAAAAACTCCTGTTTATGCTGAG
GTCAAGAGAGTTGGTGATATTATTTTTGGTTTGGCAACTCAATGTGTACA
AGCGAAAAATGTTAATAAACCATCGCCTCAGACACTTTCAAATTTATGTT
TGAAAATAAATGTGAAATTGGGCGGAATCAACAGTATTTTAGTTCCAAGT
GTTCGCCCAGCCGTGTTTAAAGAACCTGTAATATTTCTCGGAGCTGATTT
TACTCATCCTCCAGCTGGTGATAAAACAAAACCTAGTATAGCAGCTGTTG
TGGGTAGCATGGATGCTCATCCTAGTCGATACGCTGCTACTGTTAGTGTA
CAACCTCATCGACAAGAAACTATTCAAGATCTAGCTGCTATGGTTAAAGA
ATTACTGATCCAATTTTATAAATCCACCAGGTTTAAGCCAACTCGTATTA
TCTATTATCGTGATGGAGTTAGTGAAGGACAGTTTCTTAACGTTCTGAAT
CACGAATTAAAAGCAATTAGAGAAGCATGCATTAAGCTTGAAATGTCATA
TCAACCAGGCATTACTTTCGTTGTAGTTCAAAAACGACATCATACCAGAC
TCTTTTGTTCTGATAAAAAAGATCAAATGGGTCGATCTGGAAATATTCCT
GCTGGAACCACTGTTGACCAAATTATAACTCATCCTACTGAATTCGACTT
CTACCTCTGTAGTCATGCGGGAATTCAAGGTACCTCACGACCAAGTCATT
ATCATGTATTATGGGATGATAATCGATTCTCAGCTGATGAAATTCAAACT
TTGACATATCAACTTTGTCATACTTATGTTAGATGTACAAGATCTGTGTC
AATACCAGCTCCTGCTTATTATGCGCATCTCGTTGCTTTTAGAGCTCGAT
ATCATTTGGTCGAAAAGGAGCTTGATAGTGGGGAAGGATCCCAAAAATCT
GGAAACTCAGATGAAAGAAACCCCACTGCTATGATGAGGGCTGTTACTGT
TCACAGTGAAACGTTGAAAGTGATGTATTTTGCTTAACGCGTCATTTAGT
TTTCGTTATTAATTTTGACCGTTTTGAATGTGTAACCAATCGTCTTGGGA
TTGTGTAGATGTATAAATTAAACACTGCCCAAGGCGATCTTGTTAAGCCA
GTAGGTGGTTGCGCTATTAATTTGAAGCCATATTCCGCATGTTCGCATTG
TATCTTATTTTATTCAATTTGGCATTGTTATTACAAATATATTATTATTT
ACCTGAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA

protein sequence of SMED30014222-orf-1

>SMED30014222-orf-1 ID=SMED30014222-orf-1|Name=SMED30014222-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=929bp
MLGGTYFTPPTYLFNSNGNNENNSAILGLAATPNGNQTMNPLGAPGQPPN
TSVPAIIGSTQLSSNISSGPSPPQLPTGSNSQYSSSGNGSVYFQPPSRPD
QGTDGRTIQLKANHFEIVMPKGFLHHYDITITPEKCPRRVNRDIIQAMVN
NMHYQKYFYNQKPVFDGRRNMYTREPLSIGKEKLELEVILPGEGKDRVFK
VCLKHVSEVSLFALEEALQGRRQTIPAETVTALDVIMRHLPSMTYTPVGR
SFFHNTGDYDNPLGGGREVWFGFHQSVRPSQWKMMLNIDVSATAFYKEQS
VINFMFEVLEIDKDLKRPLTDSQRVKFTKEIKGLKVEINHCGPIKRKYRV
CNVTRRSAQSQTFPLQSEQGQTIECTVTKYFQDRYGMKLQHPHLPCLQVG
QEQKHTYLPLEVCNIVSGQRCIKKLTDMQTSTMIKATARSAPDREKEINN
LVRRSNFNADPHLQIFGVSVNTRMADIQGRVIPAPKIQYGGRTKAQATPQ
QGVWDMRGKQFFSGIEIKVWAIACFAPQRTVREDSLRTFTQQLQKISNDA
GMPIVGQPCFCKYATGQDQVEPMFRYLKNSFSGLQLIVVVLPGKTPVYAE
VKRVGDIIFGLATQCVQAKNVNKPSPQTLSNLCLKINVKLGGINSILVPS
VRPAVFKEPVIFLGADFTHPPAGDKTKPSIAAVVGSMDAHPSRYAATVSV
QPHRQETIQDLAAMVKELLIQFYKSTRFKPTRIIYYRDGVSEGQFLNVLN
HELKAIREACIKLEMSYQPGITFVVVQKRHHTRLFCSDKKDQMGRSGNIP
AGTTVDQIITHPTEFDFYLCSHAGIQGTSRPSHYHVLWDDNRFSADEIQT
LTYQLCHTYVRCTRSVSIPAPAYYAHLVAFRARYHLVEKELDSGEGSQKS
GNSDERNPTAMMRAVTVHSETLKVMYFA*

Annotated Terms

The following terms have been associated with this transcript:

Vocabulary: **biological process**
Term	Definition
GO:0031047	gene silencing by RNA

Vocabulary: **Planarian Anatomy**
Term	Definition
PLANA:0000136	whole organism

Vocabulary: **INTERPRO**
Term	Definition
IPR036397	RNaseH_sf
IPR036085	PAZ_dom_sf
IPR014811	ArgoL1
IPR032474	Argonaute_N
IPR032473	Argonaute_Mid_dom
IPR012337	RNaseH-like_sf
IPR032472	ArgoL2
IPR003100	PAZ_dom
IPR003165	Piwi

Vocabulary: **molecular function**
Term	Definition
GO:0005515	protein binding
GO:0003676	nucleic acid binding

InterPro

Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01


IPR Term	IPR Description	Source	Source Term	Source Description	Alignment
IPR003165	Piwi domain	SMART	SM00950	Piwi_a_2	coord: 586..885 e-value: 2.0E-129 score: 445.9
IPR003165	Piwi domain	PFAM	PF02171	Piwi	coord: 586..884 e-value: 1.7E-113 score: 378.9
IPR003165	Piwi domain	PROSITE	PS50822	PIWI	coord: 586..885 score: 52.271
IPR014811	Argonaute, linker 1 domain	SMART	SM01163	DUF1785_2	coord: 246..298 e-value: 1.2E-27 score: 107.9
IPR014811	Argonaute, linker 1 domain	PFAM	PF08699	ArgoL1	coord: 247..297 e-value: 7.6E-23 score: 79.9
IPR003100	PAZ domain	SMART	SM00949	PAZ_2_a_3	coord: 299..439 e-value: 2.7E-5 score: 28.0
IPR003100	PAZ domain	PFAM	PF02170	PAZ	coord: 315..434 e-value: 3.0E-26 score: 91.9
IPR003100	PAZ domain	PROSITE	PS50821	PAZ	coord: 299..417 score: 30.391
None	No IPR available	GENE3D	G3DSA:2.170.260.10		coord: 292..422 e-value: 5.4E-43 score: 148.2
None	No IPR available	GENE3D	G3DSA:3.40.50.2300		coord: 481..650 e-value: 8.2E-65 score: 219.6
None	No IPR available	MOBIDB_LITE	mobidb-lite	disorder_prediction	coord: 63..89
None	No IPR available	PANTHER	PTHR22891	EUKARYOTIC TRANSLATION INITIATION FACTOR 2C	coord: 90..885
None	No IPR available	PANTHER	PTHR22891:SF59	PROTEIN ARGONAUTE-2	coord: 90..885
None	No IPR available	CDD	cd02846	PAZ_argonaute_like	coord: 298..416 e-value: 5.78678E-38 score: 135.523
None	No IPR available	CDD	cd04657	Piwi_ago-like	coord: 461..885 e-value: 0.0 score: 661.231
IPR032472	Argonaute linker 2 domain	PFAM	PF16488	ArgoL2	coord: 443..489 e-value: 6.6E-12 score: 45.6
IPR032473	Protein argonaute, Mid domain	PFAM	PF16487	ArgoMid	coord: 498..579 e-value: 1.2E-34 score: 118.4
IPR032474	Protein argonaute, N-terminal	PFAM	PF16486	ArgoN	coord: 106..237 e-value: 3.2E-27 score: 95.8
IPR036397	Ribonuclease H superfamily	GENE3D	G3DSA:3.30.420.10		coord: 651..885 e-value: 1.1E-123 score: 413.8
IPR012337	Ribonuclease H-like superfamily	SUPERFAMILY	SSF53098	Ribonuclease H-like	coord: 583..885
IPR036085	PAZ domain superfamily	SUPERFAMILY	SSF101690	PAZ domain	coord: 108..458

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AGO-2

Zeng et. al., 2018

Overview

Single cell RNA-seq of pluripotent neoblasts and its early progenies

Explore this single cell expression dataset with our NB Cluster Shiny App

Davies et. al., 2017

PAGE et. al., 2020

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE

PAGE Curations: 1

Owlery

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