Centrosome-associated protein 350
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Overview
Neoblast Clusters
Zeng et. al., 2018▻ Overview▻ Neoblast Population▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Overview
Single cell RNA-seq of pluripotent neoblasts and its early progeniesWe isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)Explore this single cell expression dataset with our NB Cluster Shiny App
Neoblast Population
Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Embryonic Expression
Davies et. al., 2017
Hover the mouse over a column in the graph to view average RPKM values per sample. Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult. back to top Anatomical Expression
PAGE et. al., 2020SMED30014136 has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGEPAGE Curations: 7
Homology
BLAST of Centrosome-associated protein 350 vs. Ensembl Human
Match: DCTN1 (dynactin subunit 1 [Source:HGNC Symbol;Acc:HGNC:2711]) HSP 1 Score: 101.679 bits (252), Expect = 6.441e-21 Identity = 118/562 (21.00%), Postives = 250/562 (44.48%), Query Frame = 1
Query: 1186 LQILKKKEYKRCGDLEKLNNELQRELLDAKEREERIKKEFDSYRDMMRSGEEEIEMITIDKEMAEEKLEQVNQDYRNLKKLYEQVLEENSMLK------NSDGTSDAKIFIDQTSTINKYKNALLELSQSINCYKEENRNL-------NSELDILKELQIFQENESEQLKSKIEKHEKDLKEMKDLVDSTADVEVILDKLTFKNXXXXXXXXXXXXXXXXXXXXXXXXXXVIESKDKKIREFHEECDCLNLIVNEIQNALDKKKIENSELLKTTNQMNERICXXXXXXXXXXXXXXXXXXXVKK-----AKAKD--RELS----------------SLTFSKQNIEKNEMKRDIENKLKTIEISHKSHQVQLLIQYLPASFSLPGGEHDLIETVQIVDKLIDKISLVLEYIIQKRRLYQQRDNSEKTP-------ENICIQYKLEFLLLIWCGLLKQLQINIHHSSPEALCQLRSEFKQILQQEQNIDLLIDLMKKQCLDNSRNFSGVLQSIAFFQNFYADRFCYQQIDCNLKMENFISILSKGSECLRNDLSWIDQMLENN 2742
+Q K K ++ DL++ E ++E +A E +ER Y + M + IEM T+DKEMAEE+ E + Q+ LK+ +++ + +LK SDG + + + K+AL+ + + K+E+ L N EL+++++ + E+L+ ++ + E + E+K+ VD+ E +++ LT +N +E K +++RE + + +N + +E+Q + ++E E L + R+ ++ + + + +KK A +D REL+ + F + E + IE +L+ +E++ + + LL ++P SF PGG+HD + + ++ +LI K L+ + +K ++ +N + P E + L + L + L + + + S + ++ S + ++ E+++D LI+L+ K LD + N + ++I ++Q+ Y+ Q DC +++ + I +C+ ++ + L+
Sbjct: 238 VQEWKSKMQEQQADLQRRLKEARKEAKEALEAKER-------YMEEMADTADAIEMATLDKEMAEERAESLQQEVEALKERVDELTTDLEILKAEIEEKGSDGAASSYQLKQLEEQNARLKDALVRMRDLSSSEKQEHVKLQKLMEKKNQELEVVRQ-------QRERLQEELSQAESTIDELKEQVDAALGAEEMVEMLTDRNLN-------------------------LEEKVRELRETVGDLEAMNEMNDELQENARETELELREQL---DMAGARVREAQKRVEAAQETVADYQQTIKKYRQLTAHLQDVNRELTNQQEASVERQQQPPPETFDFKIKFAETKAHAKAIEMELRQMEVAQANRHMSLLTAFMPDSFLRPGGDHDCVLVLLLMPRLICKAELIRKQAQEK---FELSENCSERPGLRGAAGEQLSFAAGLVYSLSLLQATLHRYEHALSQCSVDVYKKVGSLYPEMSAHERSLDFLIELLHKDQLDETVNVEPLTKAIKYYQHLYSIHLAEQPEDCTMQLADHIKFTQSALDCMSVEVGRLRAFLQGG 754 HSP 2 Score: 67.781 bits (164), Expect = 1.751e-10 Identity = 40/112 (35.71%), Postives = 60/112 (53.57%), Query Frame = 1
Query: 145 GTVRFIGSTASAKGTFYGIELHTADGRTDGTMDGISYFECKEKHGIFARRSQLTKIQ-STEVTSSE--NEVHDKLLNSCGETRDLTAQTSDKIASHIKTNNIVTSVPSIINS 471
GTV ++G+T A G + G+ L A G+ DGT+ G YF C E HGIF R+SQ+ + + TS E + K+L E D TA+TS K+ + + + + S+ S
Sbjct: 42 GTVAYVGATLFATGKWVGVILDEAKGKNDGTVQGRKYFTCDEGHGIFVRQSQIQVFEDGADTTSPETPDSSASKVLKR--EGTDTTAKTS-KLPTRPASTGVAGASSSLGPS 150
BLAST of Centrosome-associated protein 350 vs. Ensembl Human
Match: DCTN1 (dynactin subunit 1 [Source:HGNC Symbol;Acc:HGNC:2711]) HSP 1 Score: 101.679 bits (252), Expect = 7.006e-21 Identity = 118/562 (21.00%), Postives = 250/562 (44.48%), Query Frame = 1
Query: 1186 LQILKKKEYKRCGDLEKLNNELQRELLDAKEREERIKKEFDSYRDMMRSGEEEIEMITIDKEMAEEKLEQVNQDYRNLKKLYEQVLEENSMLK------NSDGTSDAKIFIDQTSTINKYKNALLELSQSINCYKEENRNL-------NSELDILKELQIFQENESEQLKSKIEKHEKDLKEMKDLVDSTADVEVILDKLTFKNXXXXXXXXXXXXXXXXXXXXXXXXXXVIESKDKKIREFHEECDCLNLIVNEIQNALDKKKIENSELLKTTNQMNERICXXXXXXXXXXXXXXXXXXXVKK-----AKAKD--RELS----------------SLTFSKQNIEKNEMKRDIENKLKTIEISHKSHQVQLLIQYLPASFSLPGGEHDLIETVQIVDKLIDKISLVLEYIIQKRRLYQQRDNSEKTP-------ENICIQYKLEFLLLIWCGLLKQLQINIHHSSPEALCQLRSEFKQILQQEQNIDLLIDLMKKQCLDNSRNFSGVLQSIAFFQNFYADRFCYQQIDCNLKMENFISILSKGSECLRNDLSWIDQMLENN 2742
+Q K K ++ DL++ E ++E +A E +ER Y + M + IEM T+DKEMAEE+ E + Q+ LK+ +++ + +LK SDG + + + K+AL+ + + K+E+ L N EL+++++ + E+L+ ++ + E + E+K+ VD+ E +++ LT +N +E K +++RE + + +N + +E+Q + ++E E L + R+ ++ + + + +KK A +D REL+ + F + E + IE +L+ +E++ + + LL ++P SF PGG+HD + + ++ +LI K L+ + +K ++ +N + P E + L + L + L + + + S + ++ S + ++ E+++D LI+L+ K LD + N + ++I ++Q+ Y+ Q DC +++ + I +C+ ++ + L+
Sbjct: 251 VQEWKSKMQEQQADLQRRLKEARKEAKEALEAKER-------YMEEMADTADAIEMATLDKEMAEERAESLQQEVEALKERVDELTTDLEILKAEIEEKGSDGAASSYQLKQLEEQNARLKDALVRMRDLSSSEKQEHVKLQKLMEKKNQELEVVRQ-------QRERLQEELSQAESTIDELKEQVDAALGAEEMVEMLTDRNLN-------------------------LEEKVRELRETVGDLEAMNEMNDELQENARETELELREQL---DMAGARVREAQKRVEAAQETVADYQQTIKKYRQLTAHLQDVNRELTNQQEASVERQQQPPPETFDFKIKFAETKAHAKAIEMELRQMEVAQANRHMSLLTAFMPDSFLRPGGDHDCVLVLLLMPRLICKAELIRKQAQEK---FELSENCSERPGLRGAAGEQLSFAAGLVYSLSLLQATLHRYEHALSQCSVDVYKKVGSLYPEMSAHERSLDFLIELLHKDQLDETVNVEPLTKAIKYYQHLYSIHLAEQPEDCTMQLADHIKFTQSALDCMSVEVGRLRAFLQGG 767 HSP 2 Score: 67.781 bits (164), Expect = 1.460e-10 Identity = 42/113 (37.17%), Postives = 59/113 (52.21%), Query Frame = 1
Query: 145 GTVRFIGSTASAKGTFYGIELHTADGRTDGTMDGISYFECKEKHGIFARRSQLTKIQ-STEVTSSE--NEVHDKLLNSCGETRDLTAQTSDKIASHIKTNNIVTSVPSIINST 474
GTV ++G+T A G + G+ L A G+ DGT+ G YF C E HGIF R+SQ+ + + TS E + K+L E D TA+TS K+A + P+ ST
Sbjct: 42 GTVAYVGATLFATGKWVGVILDEAKGKNDGTVQGRKYFTCDEGHGIFVRQSQIQVFEDGADTTSPETPDSSASKVLKR--EGTDTTAKTS-KLAPTARKTTTRRPKPTRPAST 151
BLAST of Centrosome-associated protein 350 vs. Ensembl Human
Match: DCTN1 (dynactin subunit 1 [Source:HGNC Symbol;Acc:HGNC:2711]) HSP 1 Score: 101.679 bits (252), Expect = 7.086e-21 Identity = 118/562 (21.00%), Postives = 250/562 (44.48%), Query Frame = 1
Query: 1186 LQILKKKEYKRCGDLEKLNNELQRELLDAKEREERIKKEFDSYRDMMRSGEEEIEMITIDKEMAEEKLEQVNQDYRNLKKLYEQVLEENSMLK------NSDGTSDAKIFIDQTSTINKYKNALLELSQSINCYKEENRNL-------NSELDILKELQIFQENESEQLKSKIEKHEKDLKEMKDLVDSTADVEVILDKLTFKNXXXXXXXXXXXXXXXXXXXXXXXXXXVIESKDKKIREFHEECDCLNLIVNEIQNALDKKKIENSELLKTTNQMNERICXXXXXXXXXXXXXXXXXXXVKK-----AKAKD--RELS----------------SLTFSKQNIEKNEMKRDIENKLKTIEISHKSHQVQLLIQYLPASFSLPGGEHDLIETVQIVDKLIDKISLVLEYIIQKRRLYQQRDNSEKTP-------ENICIQYKLEFLLLIWCGLLKQLQINIHHSSPEALCQLRSEFKQILQQEQNIDLLIDLMKKQCLDNSRNFSGVLQSIAFFQNFYADRFCYQQIDCNLKMENFISILSKGSECLRNDLSWIDQMLENN 2742
+Q K K ++ DL++ E ++E +A E +ER Y + M + IEM T+DKEMAEE+ E + Q+ LK+ +++ + +LK SDG + + + K+AL+ + + K+E+ L N EL+++++ + E+L+ ++ + E + E+K+ VD+ E +++ LT +N +E K +++RE + + +N + +E+Q + ++E E L + R+ ++ + + + +KK A +D REL+ + F + E + IE +L+ +E++ + + LL ++P SF PGG+HD + + ++ +LI K L+ + +K ++ +N + P E + L + L + L + + + S + ++ S + ++ E+++D LI+L+ K LD + N + ++I ++Q+ Y+ Q DC +++ + I +C+ ++ + L+
Sbjct: 258 VQEWKSKMQEQQADLQRRLKEARKEAKEALEAKER-------YMEEMADTADAIEMATLDKEMAEERAESLQQEVEALKERVDELTTDLEILKAEIEEKGSDGAASSYQLKQLEEQNARLKDALVRMRDLSSSEKQEHVKLQKLMEKKNQELEVVRQ-------QRERLQEELSQAESTIDELKEQVDAALGAEEMVEMLTDRNLN-------------------------LEEKVRELRETVGDLEAMNEMNDELQENARETELELREQL---DMAGARVREAQKRVEAAQETVADYQQTIKKYRQLTAHLQDVNRELTNQQEASVERQQQPPPETFDFKIKFAETKAHAKAIEMELRQMEVAQANRHMSLLTAFMPDSFLRPGGDHDCVLVLLLMPRLICKAELIRKQAQEK---FELSENCSERPGLRGAAGEQLSFAAGLVYSLSLLQATLHRYEHALSQCSVDVYKKVGSLYPEMSAHERSLDFLIELLHKDQLDETVNVEPLTKAIKYYQHLYSIHLAEQPEDCTMQLADHIKFTQSALDCMSVEVGRLRAFLQGG 774 HSP 2 Score: 65.855 bits (159), Expect = 5.803e-10 Identity = 37/90 (41.11%), Postives = 51/90 (56.67%), Query Frame = 1
Query: 145 GTVRFIGSTASAKGTFYGIELHTADGRTDGTMDGISYFECKEKHGIFARRSQLTKIQ-STEVTSSE--NEVHDKLLNSCGETRDLTAQTS 405
GTV ++G+T A G + G+ L A G+ DGT+ G YF C E HGIF R+SQ+ + + TS E + K+L E D TA+TS
Sbjct: 42 GTVAYVGATLFATGKWVGVILDEAKGKNDGTVQGRKYFTCDEGHGIFVRQSQIQVFEDGADTTSPETPDSSASKVLKR--EGTDTTAKTS 129
BLAST of Centrosome-associated protein 350 vs. Ensembl Human
Match: DCTN1 (dynactin subunit 1 [Source:HGNC Symbol;Acc:HGNC:2711]) HSP 1 Score: 101.679 bits (252), Expect = 7.575e-21 Identity = 118/562 (21.00%), Postives = 250/562 (44.48%), Query Frame = 1
Query: 1186 LQILKKKEYKRCGDLEKLNNELQRELLDAKEREERIKKEFDSYRDMMRSGEEEIEMITIDKEMAEEKLEQVNQDYRNLKKLYEQVLEENSMLK------NSDGTSDAKIFIDQTSTINKYKNALLELSQSINCYKEENRNL-------NSELDILKELQIFQENESEQLKSKIEKHEKDLKEMKDLVDSTADVEVILDKLTFKNXXXXXXXXXXXXXXXXXXXXXXXXXXVIESKDKKIREFHEECDCLNLIVNEIQNALDKKKIENSELLKTTNQMNERICXXXXXXXXXXXXXXXXXXXVKK-----AKAKD--RELS----------------SLTFSKQNIEKNEMKRDIENKLKTIEISHKSHQVQLLIQYLPASFSLPGGEHDLIETVQIVDKLIDKISLVLEYIIQKRRLYQQRDNSEKTP-------ENICIQYKLEFLLLIWCGLLKQLQINIHHSSPEALCQLRSEFKQILQQEQNIDLLIDLMKKQCLDNSRNFSGVLQSIAFFQNFYADRFCYQQIDCNLKMENFISILSKGSECLRNDLSWIDQMLENN 2742
+Q K K ++ DL++ E ++E +A E +ER Y + M + IEM T+DKEMAEE+ E + Q+ LK+ +++ + +LK SDG + + + K+AL+ + + K+E+ L N EL+++++ + E+L+ ++ + E + E+K+ VD+ E +++ LT +N +E K +++RE + + +N + +E+Q + ++E E L + R+ ++ + + + +KK A +D REL+ + F + E + IE +L+ +E++ + + LL ++P SF PGG+HD + + ++ +LI K L+ + +K ++ +N + P E + L + L + L + + + S + ++ S + ++ E+++D LI+L+ K LD + N + ++I ++Q+ Y+ Q DC +++ + I +C+ ++ + L+
Sbjct: 221 VQEWKSKMQEQQADLQRRLKEARKEAKEALEAKER-------YMEEMADTADAIEMATLDKEMAEERAESLQQEVEALKERVDELTTDLEILKAEIEEKGSDGAASSYQLKQLEEQNARLKDALVRMRDLSSSEKQEHVKLQKLMEKKNQELEVVRQ-------QRERLQEELSQAESTIDELKEQVDAALGAEEMVEMLTDRNLN-------------------------LEEKVRELRETVGDLEAMNEMNDELQENARETELELREQL---DMAGARVREAQKRVEAAQETVADYQQTIKKYRQLTAHLQDVNRELTNQQEASVERQQQPPPETFDFKIKFAETKAHAKAIEMELRQMEVAQANRHMSLLTAFMPDSFLRPGGDHDCVLVLLLMPRLICKAELIRKQAQEK---FELSENCSERPGLRGAAGEQLSFAAGLVYSLSLLQATLHRYEHALSQCSVDVYKKVGSLYPEMSAHERSLDFLIELLHKDQLDETVNVEPLTKAIKYYQHLYSIHLAEQPEDCTMQLADHIKFTQSALDCMSVEVGRLRAFLQGG 737 HSP 2 Score: 67.781 bits (164), Expect = 1.603e-10 Identity = 40/112 (35.71%), Postives = 60/112 (53.57%), Query Frame = 1
Query: 145 GTVRFIGSTASAKGTFYGIELHTADGRTDGTMDGISYFECKEKHGIFARRSQLTKIQ-STEVTSSE--NEVHDKLLNSCGETRDLTAQTSDKIASHIKTNNIVTSVPSIINS 471
GTV ++G+T A G + G+ L A G+ DGT+ G YF C E HGIF R+SQ+ + + TS E + K+L E D TA+TS K+ + + + + S+ S
Sbjct: 25 GTVAYVGATLFATGKWVGVILDEAKGKNDGTVQGRKYFTCDEGHGIFVRQSQIQVFEDGADTTSPETPDSSASKVLKR--EGTDTTAKTS-KLPTRPASTGVAGASSSLGPS 133
BLAST of Centrosome-associated protein 350 vs. Ensembl Human
Match: DCTN1 (dynactin subunit 1 [Source:HGNC Symbol;Acc:HGNC:2711]) HSP 1 Score: 100.908 bits (250), Expect = 8.225e-21 Identity = 115/562 (20.46%), Postives = 253/562 (45.02%), Query Frame = 1
Query: 1186 LQILKKKEYKRCGDLEKLNNELQRELLDAKEREERIKKEFDSYRDMMRSGEEEIEMITIDKEMAEEKLEQVNQDYRNLKKLYEQVLEENSMLK------NSDGTSDAKIFIDQTSTINKYKNALLELSQSINCYKEENRNL-------NSELDILKELQIFQENESEQLKSKIEKHEKDLKEMKDLVDSTADVEVILDKLTFKNXXXXXXXXXXXXXXXXXXXXXXXXXXVIESKDKKIREFHEECDCLNLIVNEIQNALDKKKIENSELLKTTNQMNERICXXXXXXXXXXXXXXXXXXXVKK-----AKAKD--RELS----------------SLTFSKQNIEKNEMKRDIENKLKTIEISHKSHQVQLLIQYLPASFSLPGGEHDLIETVQIVDKLIDKISLVLEYIIQKRRLYQQRDNSEKTP-------ENICIQYKLEFLLLIWCGLLKQLQINIHHSSPEALCQLRSEFKQILQQEQNIDLLIDLMKKQCLDNSRNFSGVLQSIAFFQNFYADRFCYQQIDCNLKMENFISILSKGSECLRNDLSWIDQMLENN 2742
+Q+ + +E+K +++ +LQR L +A++ + + + Y + M + IEM T+DKEMAEE+ E + Q+ LK+ +++ + +LK SDG + + + K+AL+ + + K+E+ L N EL+++++ + E+L+ ++ + E + E+K+ VD+ E +++ LT +N +E K +++RE + + +N + +E+Q + ++E E L + R+ ++ + + + +KK A +D REL+ + F + E + IE +L+ +E++ + + LL ++P SF PGG+HD + + ++ +LI K L+ + +K ++ +N + P E + L + L + L + + + S + ++ S + ++ E+++D LI+L+ K LD + N + ++I ++Q+ Y+ Q DC +++ + I +C+ ++ + L+
Sbjct: 216 IQLEQVQEWK--SKMQEQQADLQRRLKEARKEAKEALEAKERYMEEMADTADAIEMATLDKEMAEERAESLQQEVEALKERVDELTTDLEILKAEIEEKGSDGAASSYQLKQLEEQNARLKDALVRMRDLSSSEKQEHVKLQKLMEKKNQELEVVRQ-------QRERLQEELSQAESTIDELKEQVDAALGAEEMVEMLTDRNLN-------------------------LEEKVRELRETVGDLEAMNEMNDELQENARETELELREQL---DMAGARVREAQKRVEAAQETVADYQQTIKKYRQLTAHLQDVNRELTNQQEASVERQQQPPPETFDFKIKFAETKAHAKAIEMELRQMEVAQANRHMSLLTAFMPDSFLRPGGDHDCVLVLLLMPRLICKAELIRKQAQEK---FELSENCSERPGLRGAAGEQLSFAAGLVYSLSLLQATLHRYEHALSQCSVDVYKKVGSLYPEMSAHERSLDFLIELLHKDQLDETVNVEPLTKAIKYYQHLYSIHLAEQPEDCTMQLADHIKFTQSALDCMSVEVGRLRAFLQGG 737 HSP 2 Score: 67.3958 bits (163), Expect = 1.615e-10 Identity = 40/112 (35.71%), Postives = 60/112 (53.57%), Query Frame = 1
Query: 145 GTVRFIGSTASAKGTFYGIELHTADGRTDGTMDGISYFECKEKHGIFARRSQLTKIQ-STEVTSSE--NEVHDKLLNSCGETRDLTAQTSDKIASHIKTNNIVTSVPSIINS 471
GTV ++G+T A G + G+ L A G+ DGT+ G YF C E HGIF R+SQ+ + + TS E + K+L E D TA+TS K+ + + + + S+ S
Sbjct: 25 GTVAYVGATLFATGKWVGVILDEAKGKNDGTVQGRKYFTCDEGHGIFVRQSQIQVFEDGADTTSPETPDSSASKVLKR--EGTDTTAKTS-KLPTRPASTGVAGASSSLGPS 133
BLAST of Centrosome-associated protein 350 vs. Ensembl Celegans
Match: dnc-1 (DyNactin Complex component [Source:UniProtKB/TrEMBL;Acc:E2JKZ0]) HSP 1 Score: 69.3218 bits (168), Expect = 1.926e-11 Identity = 102/483 (21.12%), Postives = 235/483 (48.65%), Query Frame = 1
Query: 1246 ELQRELLDAKEREERIKKEFDSYRDMMRSGEEEIEMITIDKEMAEEKLEQVNQDYRNLKKLYEQVLEENSMLKN--SDGTSDAKIF----IDQTSTIN-KYKNALLELSQSINCYKEENRNLNSE--LDILKEL----QIFQENE-----SEQLKSKIEKHEKDLKEMKDLVDSTADVEVILDKLTFKNXXXXXXXXXXXXXXXXXXXXXXXXXXVIESKDKKIREFHEECDCLNLIVNEIQNALDKKKIENSELLKTTNQMNERICXXXXXXXXXXXXXXXXXXXVKKAKAKDRELSSLTFSKQNIEKNEMKRDIENKLKTIEISHKSHQVQLLIQYLPASFSLPGGEHDLIETVQIVDKLIDKISLVLEYIIQ--------KRRLYQQRDNSEKTPENICIQYKLEFLLLIWCGLLKQLQINIHHSSPEALCQLRSEFKQILQQEQNIDLLIDLMKKQCLDNSRNFSGVLQSIAFFQNFYA 2616
EL++++ D + +E+++ D + ++ ++ +EM TI+KE+AEE+ + + D L + E + E +LK ++G A++ + Q N K K+AL++L R+LN++ LD K + ++ EN +E LK + E E + ++ +D+ E ++ +LT KN +E+ + +L++ + ++++ D ++ E + +++++ +E + L + ++E+ + ++ +L +T + ER+ L +++++++ ++ E + + D + +S+ Q D+E ++ IE+ Q L +LP +FS GGE+D I V ++ +L K L Q RR + + + + ++ ++ +L L +L+ I ++ E L +L + ++ E+ +D ++L+KK D + + ++ + +FQN ++
Sbjct: 320 ELEKQIGDERIAKEQLQAWQDENKVLLSDHQDTMEMATIEKELAEERADSLQNDVLTLTEKLESMETELEILKEEMANGGGAAQVGNSVQMKQIEIQNDKLKDALIKL-----------RDLNAQATLDRQKAVDEAERLKTENSELIRVAENLKRQTEIAESKIAGFQEQIDAAMGAEAMVTQLTDKNFNMEERIMQLEETIEDMEEARDLDEQLAEVQKQQVKDLMKEIEQLKIHIHELNGRIRDEQKHAVDLSQTILKFRERMANLNSQIQDQKDQVLSLEEQLHGHISVDNDRASMVNQLQISANRNFAEDVERQVNAIEVEFARRQAGYLKAFLPDNFSRVGGENDSILLVVMLPRLAAKTKLFASLAAQCFPQVPGGMRREHVTKSHKGEQWAHVA---RVNYLANSINAALGKLESAIGETTVEVLIKLTETYGEMSTHEKTVDQYLELLKKSRFDENTSLDSFVRPLVYFQNMFS 788 HSP 2 Score: 55.8398 bits (133), Expect = 2.349e-7 Identity = 26/67 (38.81%), Postives = 39/67 (58.21%), Query Frame = 1
Query: 103 FQIGDSVLYNSKLEGTVRFIGSTASAKGTFYGIELHTADGRTDGTMDGISYFECKEKHGIFARRSQL 303
F+IG V +S G V F G T A+G + G+ L TA G+ +GT+ + YFEC+ G+F + S +
Sbjct: 3 FEIGTRVKTSSG-NGRVVFCGQTQFAEGDWVGVILDTATGKNNGTVQNVQYFECEPNFGVFVKSSAV 68
BLAST of Centrosome-associated protein 350 vs. Ensembl Celegans
Match: dnc-1 (DyNactin Complex component [Source:UniProtKB/TrEMBL;Acc:E2JKZ0]) HSP 1 Score: 69.3218 bits (168), Expect = 1.938e-11 Identity = 102/483 (21.12%), Postives = 235/483 (48.65%), Query Frame = 1
Query: 1246 ELQRELLDAKEREERIKKEFDSYRDMMRSGEEEIEMITIDKEMAEEKLEQVNQDYRNLKKLYEQVLEENSMLKN--SDGTSDAKIF----IDQTSTIN-KYKNALLELSQSINCYKEENRNLNSE--LDILKEL----QIFQENE-----SEQLKSKIEKHEKDLKEMKDLVDSTADVEVILDKLTFKNXXXXXXXXXXXXXXXXXXXXXXXXXXVIESKDKKIREFHEECDCLNLIVNEIQNALDKKKIENSELLKTTNQMNERICXXXXXXXXXXXXXXXXXXXVKKAKAKDRELSSLTFSKQNIEKNEMKRDIENKLKTIEISHKSHQVQLLIQYLPASFSLPGGEHDLIETVQIVDKLIDKISLVLEYIIQ--------KRRLYQQRDNSEKTPENICIQYKLEFLLLIWCGLLKQLQINIHHSSPEALCQLRSEFKQILQQEQNIDLLIDLMKKQCLDNSRNFSGVLQSIAFFQNFYA 2616
EL++++ D + +E+++ D + ++ ++ +EM TI+KE+AEE+ + + D L + E + E +LK ++G A++ + Q N K K+AL++L R+LN++ LD K + ++ EN +E LK + E E + ++ +D+ E ++ +LT KN +E+ + +L++ + ++++ D ++ E + +++++ +E + L + ++E+ + ++ +L +T + ER+ L +++++++ ++ E + + D + +S+ Q D+E ++ IE+ Q L +LP +FS GGE+D I V ++ +L K L Q RR + + + + ++ ++ +L L +L+ I ++ E L +L + ++ E+ +D ++L+KK D + + ++ + +FQN ++
Sbjct: 348 ELEKQIGDERIAKEQLQAWQDENKVLLSDHQDTMEMATIEKELAEERADSLQNDVLTLTEKLESMETELEILKEEMANGGGAAQVGNSVQMKQIEIQNDKLKDALIKL-----------RDLNAQATLDRQKAVDEAERLKTENSELIRVAENLKRQTEIAESKIAGFQEQIDAAMGAEAMVTQLTDKNFNMEERIMQLEETIEDMEEARDLDEQLAEVQKQQVKDLMKEIEQLKIHIHELNGRIRDEQKHAVDLSQTILKFRERMANLNSQIQDQKDQVLSLEEQLHGHISVDNDRASMVNQLQISANRNFAEDVERQVNAIEVEFARRQAGYLKAFLPDNFSRVGGENDSILLVVMLPRLAAKTKLFASLAAQCFPQVPGGMRREHVTKSHKGEQWAHVA---RVNYLANSINAALGKLESAIGETTVEVLIKLTETYGEMSTHEKTVDQYLELLKKSRFDENTSLDSFVRPLVYFQNMFS 816 HSP 2 Score: 55.8398 bits (133), Expect = 2.340e-7 Identity = 26/67 (38.81%), Postives = 39/67 (58.21%), Query Frame = 1
Query: 103 FQIGDSVLYNSKLEGTVRFIGSTASAKGTFYGIELHTADGRTDGTMDGISYFECKEKHGIFARRSQL 303
F+IG V +S G V F G T A+G + G+ L TA G+ +GT+ + YFEC+ G+F + S +
Sbjct: 3 FEIGTRVKTSSG-NGRVVFCGQTQFAEGDWVGVILDTATGKNNGTVQNVQYFECEPNFGVFVKSSAV 68
BLAST of Centrosome-associated protein 350 vs. Ensembl Celegans
Match: dnc-1 (DyNactin Complex component [Source:UniProtKB/TrEMBL;Acc:E2JKZ0]) HSP 1 Score: 68.9366 bits (167), Expect = 2.735e-11 Identity = 102/483 (21.12%), Postives = 235/483 (48.65%), Query Frame = 1
Query: 1246 ELQRELLDAKEREERIKKEFDSYRDMMRSGEEEIEMITIDKEMAEEKLEQVNQDYRNLKKLYEQVLEENSMLKN--SDGTSDAKIF----IDQTSTIN-KYKNALLELSQSINCYKEENRNLNSE--LDILKEL----QIFQENE-----SEQLKSKIEKHEKDLKEMKDLVDSTADVEVILDKLTFKNXXXXXXXXXXXXXXXXXXXXXXXXXXVIESKDKKIREFHEECDCLNLIVNEIQNALDKKKIENSELLKTTNQMNERICXXXXXXXXXXXXXXXXXXXVKKAKAKDRELSSLTFSKQNIEKNEMKRDIENKLKTIEISHKSHQVQLLIQYLPASFSLPGGEHDLIETVQIVDKLIDKISLVLEYIIQ--------KRRLYQQRDNSEKTPENICIQYKLEFLLLIWCGLLKQLQINIHHSSPEALCQLRSEFKQILQQEQNIDLLIDLMKKQCLDNSRNFSGVLQSIAFFQNFYA 2616
EL++++ D + +E+++ D + ++ ++ +EM TI+KE+AEE+ + + D L + E + E +LK ++G A++ + Q N K K+AL++L R+LN++ LD K + ++ EN +E LK + E E + ++ +D+ E ++ +LT KN +E+ + +L++ + ++++ D ++ E + +++++ +E + L + ++E+ + ++ +L +T + ER+ L +++++++ ++ E + + D + +S+ Q D+E ++ IE+ Q L +LP +FS GGE+D I V ++ +L K L Q RR + + + + ++ ++ +L L +L+ I ++ E L +L + ++ E+ +D ++L+KK D + + ++ + +FQN ++
Sbjct: 110 ELEKQIGDERIAKEQLQAWQDENKVLLSDHQDTMEMATIEKELAEERADSLQNDVLTLTEKLESMETELEILKEEMANGGGAAQVGNSVQMKQIEIQNDKLKDALIKL-----------RDLNAQATLDRQKAVDEAERLKTENSELIRVAENLKRQTEIAESKIAGFQEQIDAAMGAEAMVTQLTDKNFNMEERIMQLEETIEDMEEARDLDEQLAEVQKQQVKDLMKEIEQLKIHIHELNGRIRDEQKHAVDLSQTILKFRERMANLNSQIQDQKDQVLSLEEQLHGHISVDNDRASMVNQLQISANRNFAEDVERQVNAIEVEFARRQAGYLKAFLPDNFSRVGGENDSILLVVMLPRLAAKTKLFASLAAQCFPQVPGGMRREHVTKSHKGEQWAHVA---RVNYLANSINAALGKLESAIGETTVEVLIKLTETYGEMSTHEKTVDQYLELLKKSRFDENTSLDSFVRPLVYFQNMFS 578
BLAST of Centrosome-associated protein 350 vs. Ensembl Celegans
Match: dnc-1 (DyNactin Complex component [Source:UniProtKB/TrEMBL;Acc:E2JKZ0]) HSP 1 Score: 68.5514 bits (166), Expect = 3.207e-11 Identity = 102/483 (21.12%), Postives = 235/483 (48.65%), Query Frame = 1
Query: 1246 ELQRELLDAKEREERIKKEFDSYRDMMRSGEEEIEMITIDKEMAEEKLEQVNQDYRNLKKLYEQVLEENSMLKN--SDGTSDAKIF----IDQTSTIN-KYKNALLELSQSINCYKEENRNLNSE--LDILKEL----QIFQENE-----SEQLKSKIEKHEKDLKEMKDLVDSTADVEVILDKLTFKNXXXXXXXXXXXXXXXXXXXXXXXXXXVIESKDKKIREFHEECDCLNLIVNEIQNALDKKKIENSELLKTTNQMNERICXXXXXXXXXXXXXXXXXXXVKKAKAKDRELSSLTFSKQNIEKNEMKRDIENKLKTIEISHKSHQVQLLIQYLPASFSLPGGEHDLIETVQIVDKLIDKISLVLEYIIQ--------KRRLYQQRDNSEKTPENICIQYKLEFLLLIWCGLLKQLQINIHHSSPEALCQLRSEFKQILQQEQNIDLLIDLMKKQCLDNSRNFSGVLQSIAFFQNFYA 2616
EL++++ D + +E+++ D + ++ ++ +EM TI+KE+AEE+ + + D L + E + E +LK ++G A++ + Q N K K+AL++L R+LN++ LD K + ++ EN +E LK + E E + ++ +D+ E ++ +LT KN +E+ + +L++ + ++++ D ++ E + +++++ +E + L + ++E+ + ++ +L +T + ER+ L +++++++ ++ E + + D + +S+ Q D+E ++ IE+ Q L +LP +FS GGE+D I V ++ +L K L Q RR + + + + ++ ++ +L L +L+ I ++ E L +L + ++ E+ +D ++L+KK D + + ++ + +FQN ++
Sbjct: 373 ELEKQIGDERIAKEQLQAWQDENKVLLSDHQDTMEMATIEKELAEERADSLQNDVLTLTEKLESMETELEILKEEMANGGGAAQVGNSVQMKQIEIQNDKLKDALIKL-----------RDLNAQATLDRQKAVDEAERLKTENSELIRVAENLKRQTEIAESKIAGFQEQIDAAMGAEAMVTQLTDKNFNMEERIMQLEETIEDMEEARDLDEQLAEVQKQQVKDLMKEIEQLKIHIHELNGRIRDEQKHAVDLSQTILKFRERMANLNSQIQDQKDQVLSLEEQLHGHISVDNDRASMVNQLQISANRNFAEDVERQVNAIEVEFARRQAGYLKAFLPDNFSRVGGENDSILLVVMLPRLAAKTKLFASLAAQCFPQVPGGMRREHVTKSHKGEQWAHVA---RVNYLANSINAALGKLESAIGETTVEVLIKLTETYGEMSTHEKTVDQYLELLKKSRFDENTSLDSFVRPLVYFQNMFS 841 HSP 2 Score: 55.8398 bits (133), Expect = 2.329e-7 Identity = 26/67 (38.81%), Postives = 39/67 (58.21%), Query Frame = 1
Query: 103 FQIGDSVLYNSKLEGTVRFIGSTASAKGTFYGIELHTADGRTDGTMDGISYFECKEKHGIFARRSQL 303
F+IG V +S G V F G T A+G + G+ L TA G+ +GT+ + YFEC+ G+F + S +
Sbjct: 3 FEIGTRVKTSSG-NGRVVFCGQTQFAEGDWVGVILDTATGKNNGTVQNVQYFECEPNFGVFVKSSAV 68
BLAST of Centrosome-associated protein 350 vs. Ensembl Celegans
Match: dnc-1 (DyNactin Complex component [Source:UniProtKB/TrEMBL;Acc:E2JKZ0]) HSP 1 Score: 68.5514 bits (166), Expect = 3.327e-11 Identity = 102/483 (21.12%), Postives = 235/483 (48.65%), Query Frame = 1
Query: 1246 ELQRELLDAKEREERIKKEFDSYRDMMRSGEEEIEMITIDKEMAEEKLEQVNQDYRNLKKLYEQVLEENSMLKN--SDGTSDAKIF----IDQTSTIN-KYKNALLELSQSINCYKEENRNLNSE--LDILKEL----QIFQENE-----SEQLKSKIEKHEKDLKEMKDLVDSTADVEVILDKLTFKNXXXXXXXXXXXXXXXXXXXXXXXXXXVIESKDKKIREFHEECDCLNLIVNEIQNALDKKKIENSELLKTTNQMNERICXXXXXXXXXXXXXXXXXXXVKKAKAKDRELSSLTFSKQNIEKNEMKRDIENKLKTIEISHKSHQVQLLIQYLPASFSLPGGEHDLIETVQIVDKLIDKISLVLEYIIQ--------KRRLYQQRDNSEKTPENICIQYKLEFLLLIWCGLLKQLQINIHHSSPEALCQLRSEFKQILQQEQNIDLLIDLMKKQCLDNSRNFSGVLQSIAFFQNFYA 2616
EL++++ D + +E+++ D + ++ ++ +EM TI+KE+AEE+ + + D L + E + E +LK ++G A++ + Q N K K+AL++L R+LN++ LD K + ++ EN +E LK + E E + ++ +D+ E ++ +LT KN +E+ + +L++ + ++++ D ++ E + +++++ +E + L + ++E+ + ++ +L +T + ER+ L +++++++ ++ E + + D + +S+ Q D+E ++ IE+ Q L +LP +FS GGE+D I V ++ +L K L Q RR + + + + ++ ++ +L L +L+ I ++ E L +L + ++ E+ +D ++L+KK D + + ++ + +FQN ++
Sbjct: 345 ELEKQIGDERIAKEQLQAWQDENKVLLSDHQDTMEMATIEKELAEERADSLQNDVLTLTEKLESMETELEILKEEMANGGGAAQVGNSVQMKQIEIQNDKLKDALIKL-----------RDLNAQATLDRQKAVDEAERLKTENSELIRVAENLKRQTEIAESKIAGFQEQIDAAMGAEAMVTQLTDKNFNMEERIMQLEETIEDMEEARDLDEQLAEVQKQQVKDLMKEIEQLKIHIHELNGRIRDEQKHAVDLSQTILKFRERMANLNSQIQDQKDQVLSLEEQLHGHISVDNDRASMVNQLQISANRNFAEDVERQVNAIEVEFARRQAGYLKAFLPDNFSRVGGENDSILLVVMLPRLAAKTKLFASLAAQCFPQVPGGMRREHVTKSHKGEQWAHVA---RVNYLANSINAALGKLESAIGETTVEVLIKLTETYGEMSTHEKTVDQYLELLKKSRFDENTSLDSFVRPLVYFQNMFS 813 HSP 2 Score: 55.8398 bits (133), Expect = 2.261e-7 Identity = 26/67 (38.81%), Postives = 39/67 (58.21%), Query Frame = 1
Query: 103 FQIGDSVLYNSKLEGTVRFIGSTASAKGTFYGIELHTADGRTDGTMDGISYFECKEKHGIFARRSQL 303
F+IG V +S G V F G T A+G + G+ L TA G+ +GT+ + YFEC+ G+F + S +
Sbjct: 3 FEIGTRVKTSSG-NGRVVFCGQTQFAEGDWVGVILDTATGKNNGTVQNVQYFECEPNFGVFVKSSAV 68
BLAST of Centrosome-associated protein 350 vs. Ensembl Fly
Match: Khc-73 (gene:FBgn0019968 transcript:FBtr0087357) HSP 1 Score: 72.4034 bits (176), Expect = 3.408e-12 Identity = 30/68 (44.12%), Postives = 45/68 (66.18%), Query Frame = 1
Query: 109 IGDSVL---YNSKLEGTVRFIGSTASAKGTFYGIELHTADGRTDGTMDGISYFECKEKHGIFARRSQL 303
+G+SVL YN+ G +RF+G+T G + G+EL T G+ DG++ G+ YF+CK KHG+F R +L
Sbjct: 1807 VGESVLIRPYNTS--GVIRFVGTTEFQPGAWIGVELDTPTGKNDGSVKGVQYFQCKPKHGMFVRSDKL 1872
BLAST of Centrosome-associated protein 350 vs. Ensembl Fly
Match: Khc-73 (gene:FBgn0019968 transcript:FBtr0346265) HSP 1 Score: 72.4034 bits (176), Expect = 3.612e-12 Identity = 30/68 (44.12%), Postives = 45/68 (66.18%), Query Frame = 1
Query: 109 IGDSVL---YNSKLEGTVRFIGSTASAKGTFYGIELHTADGRTDGTMDGISYFECKEKHGIFARRSQL 303
+G+SVL YN+ G +RF+G+T G + G+EL T G+ DG++ G+ YF+CK KHG+F R +L
Sbjct: 1799 VGESVLIRPYNTS--GVIRFVGTTEFQPGAWIGVELDTPTGKNDGSVKGVQYFQCKPKHGMFVRSDKL 1864
BLAST of Centrosome-associated protein 350 vs. Ensembl Fly
Match: Khc-73 (gene:FBgn0019968 transcript:FBtr0329956) HSP 1 Score: 72.0182 bits (175), Expect = 3.641e-12 Identity = 30/68 (44.12%), Postives = 45/68 (66.18%), Query Frame = 1
Query: 109 IGDSVL---YNSKLEGTVRFIGSTASAKGTFYGIELHTADGRTDGTMDGISYFECKEKHGIFARRSQL 303
+G+SVL YN+ G +RF+G+T G + G+EL T G+ DG++ G+ YF+CK KHG+F R +L
Sbjct: 1794 VGESVLIRPYNTS--GVIRFVGTTEFQPGAWIGVELDTPTGKNDGSVKGVQYFQCKPKHGMFVRSDKL 1859
BLAST of Centrosome-associated protein 350 vs. Ensembl Fly
Match: Khc-73 (gene:FBgn0019968 transcript:FBtr0329955) HSP 1 Score: 72.0182 bits (175), Expect = 3.731e-12 Identity = 30/68 (44.12%), Postives = 45/68 (66.18%), Query Frame = 1
Query: 109 IGDSVL---YNSKLEGTVRFIGSTASAKGTFYGIELHTADGRTDGTMDGISYFECKEKHGIFARRSQL 303
+G+SVL YN+ G +RF+G+T G + G+EL T G+ DG++ G+ YF+CK KHG+F R +L
Sbjct: 1785 VGESVLIRPYNTS--GVIRFVGTTEFQPGAWIGVELDTPTGKNDGSVKGVQYFQCKPKHGMFVRSDKL 1850
BLAST of Centrosome-associated protein 350 vs. Ensembl Fly
Match: Khc-73 (gene:FBgn0019968 transcript:FBtr0329957) HSP 1 Score: 72.0182 bits (175), Expect = 3.914e-12 Identity = 30/68 (44.12%), Postives = 45/68 (66.18%), Query Frame = 1
Query: 109 IGDSVL---YNSKLEGTVRFIGSTASAKGTFYGIELHTADGRTDGTMDGISYFECKEKHGIFARRSQL 303
+G+SVL YN+ G +RF+G+T G + G+EL T G+ DG++ G+ YF+CK KHG+F R +L
Sbjct: 1785 VGESVLIRPYNTS--GVIRFVGTTEFQPGAWIGVELDTPTGKNDGSVKGVQYFQCKPKHGMFVRSDKL 1850
BLAST of Centrosome-associated protein 350 vs. Ensembl Zebrafish
Match: dctn1a (dynactin 1a [Source:ZFIN;Acc:ZDB-GENE-070117-2205]) HSP 1 Score: 114.775 bits (286), Expect = 4.358e-25 Identity = 160/738 (21.68%), Postives = 347/738 (47.02%), Query Frame = 1
Query: 1228 LEKLNNELQRELLDAKEREERIKKEFDSYRDMMRSGEEEIEMITIDKEMAEEKLEQVNQDYRNLKKLYEQVLEENSML------KNSDGTSDAKIFIDQTSTIN-KYKNALLELSQSINCYKEENRNL-------NSELDILKELQIFQENESEQLKSKIEKHEKDLKEMKDLVDSTADVEVILDKLTFKNXXXXXXXXXXXXXXXXXXXXXXXXXXVIESKDKKIREFHEECDCLNLIVNEIQNALDKKKIENSELLKTTNQMNERICXXXXXXXXXXXXXXXXXXXVKKAKAKDRELSSLTFSKQNIEKNEMKRDIENKLKTIEISHKSHQVQLLIQYLPASFSLPGGEHDLIETVQIVDKLIDKISLVLEYIIQKRRL----YQQRDNSEKTPENICIQYKLEFLLLIWCGLLKQLQINIHHSSPEALCQLRSEFKQILQQEQNIDLLIDLMKKQCLDNSRNFSGVLQSIAFFQNFYADRFCYQQIDCNLKMENFISILSKGSECLRNDLSWIDQMLE-NNVGEQTLKLMDNLN-----------KISTNVQST-MKNTQMYLRHNQRITFDSSVS-KSIDGIIFSLMDIVLSISDFALQLTDERIFS-----DEAMCRLTEIFANNRNPLNPTSDNEILF-SLNSIDKQVENIVSNFKSGVYDADKLNKTFNSAIDTNATNYREKLMGLQALSFEIKLKDEMLALINQELKEKSSQLSEILMQVNFYKQKLQTA 3327
+++ N+LQ++L +AK+ + D Y + M + IEM T+DKEMAEE+ E + Q+ +LK+ E++ + +L K SDG + + + Q N + K AL+ + + K+E+ L NSEL+ L+ ++ E+L+ +++ E + E+K+ VD+ E +++ LT +N LE+++++L++ + +L+ + + E+ E+ + E E+ D V E Q ++ + ++ +T N+ E L +E + E +++ A EL F + E + IE +L+ +E+S + QV LL ++P SF GG+HD I + ++ +LI K L+ + +K L ++ E + L + L + L + ++ + + ++ + ++ E+++D LIDL+ K LD + + ++I ++Q+ Y+ C Q DC +++ + I +C+ +++ + L+ G + L+ +L+ KI + T LR +++++ + S K + ++ L ++ + + L ++ S D A + +++ LNP E L S +++ + + + + G YD+++ + ++T A R ++ + L +++ ++ ++ + + LK K +LSE ++++ ++KL T+
Sbjct: 246 MQEQQNDLQKQLKEAKKEAREALEAKDRYMEEMADTADAIEMATLDKEMAEERAESLQQETESLKEKLEELTMDMEILKHEIEEKGSDGAASS-YHVKQLEEQNARLKEALVRMRDLSSSEKQEHVKLQKQMEKKNSELETLR-------SQKEKLQEEMKLAEDTIDELKEQVDAALGAEEMVETLTERNLDLEEKVRELRETVSDLESINEMNDELQENARETELELREQLDLAGARVREAQKRVEAAQETLADYQQTINKYRELTTHLQEVNRELTNQQSSSAEQLQQPAA---EL--FDFKIKFAETKAYAKAIEMELRKMEVSQANRQVSLLTSFMPESFLRHGGDHDCILVLLLIPRLICKAELISKQAQEKFDLTGGSLERAGLRGAAGEQLSFASGLVYSLTLLQATLHKYELALSVCGVDVYKRMGMLYSEMCVHERSLDFLIDLLHKDQLDETVQVEPLTKAIKYYQHLYSVHLCDQPEDCTVQLADHIKFTQSALDCMGSEVGRLRAFLQAGQEGAELCVLLKDLDTSCGDIRQFCKKIRRRMPGTDAPGIPAALRFSEQVSEALADSRKQLARVVAVLQEVSAAGAQMMAPLQEQEGLSAVKIEDVAFKAVEQVYGTQG--LNP---YECLRQSCSAVIATMNKMATAMQEGEYDSERPQRP-PPPVETRAAAVRAEMTDAEGLGNKLEDRETVIKELKKSLKIKGEELSEANVRLSLLEKKLDTS 964 HSP 2 Score: 66.6254 bits (161), Expect = 1.946e-10 Identity = 29/70 (41.43%), Postives = 42/70 (60.00%), Query Frame = 1
Query: 145 GTVRFIGSTASAKGTFYGIELHTADGRTDGTMDGISYFECKEKHGIFARRSQLTKIQSTEVTSSENEVHD 354
GTV +IG+T A G + G+ L A G+ DGT+ G YF C+E HGIF R+SQ+ + +++ E D
Sbjct: 25 GTVAYIGATLFASGKWVGVILDEAKGKNDGTVQGKRYFTCEENHGIFVRQSQIQLMDDGGSSATSPETPD 94
BLAST of Centrosome-associated protein 350 vs. Ensembl Zebrafish
Match: dctn1a (dynactin 1a [Source:ZFIN;Acc:ZDB-GENE-070117-2205]) HSP 1 Score: 114.775 bits (286), Expect = 4.621e-25 Identity = 160/738 (21.68%), Postives = 347/738 (47.02%), Query Frame = 1
Query: 1228 LEKLNNELQRELLDAKEREERIKKEFDSYRDMMRSGEEEIEMITIDKEMAEEKLEQVNQDYRNLKKLYEQVLEENSML------KNSDGTSDAKIFIDQTSTIN-KYKNALLELSQSINCYKEENRNL-------NSELDILKELQIFQENESEQLKSKIEKHEKDLKEMKDLVDSTADVEVILDKLTFKNXXXXXXXXXXXXXXXXXXXXXXXXXXVIESKDKKIREFHEECDCLNLIVNEIQNALDKKKIENSELLKTTNQMNERICXXXXXXXXXXXXXXXXXXXVKKAKAKDRELSSLTFSKQNIEKNEMKRDIENKLKTIEISHKSHQVQLLIQYLPASFSLPGGEHDLIETVQIVDKLIDKISLVLEYIIQKRRL----YQQRDNSEKTPENICIQYKLEFLLLIWCGLLKQLQINIHHSSPEALCQLRSEFKQILQQEQNIDLLIDLMKKQCLDNSRNFSGVLQSIAFFQNFYADRFCYQQIDCNLKMENFISILSKGSECLRNDLSWIDQMLE-NNVGEQTLKLMDNLN-----------KISTNVQST-MKNTQMYLRHNQRITFDSSVS-KSIDGIIFSLMDIVLSISDFALQLTDERIFS-----DEAMCRLTEIFANNRNPLNPTSDNEILF-SLNSIDKQVENIVSNFKSGVYDADKLNKTFNSAIDTNATNYREKLMGLQALSFEIKLKDEMLALINQELKEKSSQLSEILMQVNFYKQKLQTA 3327
+++ N+LQ++L +AK+ + D Y + M + IEM T+DKEMAEE+ E + Q+ +LK+ E++ + +L K SDG + + + Q N + K AL+ + + K+E+ L NSEL+ L+ ++ E+L+ +++ E + E+K+ VD+ E +++ LT +N LE+++++L++ + +L+ + + E+ E+ + E E+ D V E Q ++ + ++ +T N+ E L +E + E +++ A EL F + E + IE +L+ +E+S + QV LL ++P SF GG+HD I + ++ +LI K L+ + +K L ++ E + L + L + L + ++ + + ++ + ++ E+++D LIDL+ K LD + + ++I ++Q+ Y+ C Q DC +++ + I +C+ +++ + L+ G + L+ +L+ KI + T LR +++++ + S K + ++ L ++ + + L ++ S D A + +++ LNP E L S +++ + + + + G YD+++ + ++T A R ++ + L +++ ++ ++ + + LK K +LSE ++++ ++KL T+
Sbjct: 214 MQEQQNDLQKQLKEAKKEAREALEAKDRYMEEMADTADAIEMATLDKEMAEERAESLQQETESLKEKLEELTMDMEILKHEIEEKGSDGAASS-YHVKQLEEQNARLKEALVRMRDLSSSEKQEHVKLQKQMEKKNSELETLR-------SQKEKLQEEMKLAEDTIDELKEQVDAALGAEEMVETLTERNLDLEEKVRELRETVSDLESINEMNDELQENARETELELREQLDLAGARVREAQKRVEAAQETLADYQQTINKYRELTTHLQEVNRELTNQQSSSAEQLQQPAA---EL--FDFKIKFAETKAYAKAIEMELRKMEVSQANRQVSLLTSFMPESFLRHGGDHDCILVLLLIPRLICKAELISKQAQEKFDLTGGSLERAGLRGAAGEQLSFASGLVYSLTLLQATLHKYELALSVCGVDVYKRMGMLYSEMCVHERSLDFLIDLLHKDQLDETVQVEPLTKAIKYYQHLYSVHLCDQPEDCTVQLADHIKFTQSALDCMGSEVGRLRAFLQAGQEGAELCVLLKDLDTSCGDIRQFCKKIRRRMPGTDAPGIPAALRFSEQVSEALADSRKQLARVVAVLQEVSAAGAQMMAPLQEQEGLSAVKIEDVAFKAVEQVYGTQG--LNP---YECLRQSCSAVIATMNKMATAMQEGEYDSERPQRP-PPPVETRAAAVRAEMTDAEGLGNKLEDRETVIKELKKSLKIKGEELSEANVRLSLLEKKLDTS 932 HSP 2 Score: 67.0106 bits (162), Expect = 1.899e-10 Identity = 29/70 (41.43%), Postives = 42/70 (60.00%), Query Frame = 1
Query: 145 GTVRFIGSTASAKGTFYGIELHTADGRTDGTMDGISYFECKEKHGIFARRSQLTKIQSTEVTSSENEVHD 354
GTV +IG+T A G + G+ L A G+ DGT+ G YF C+E HGIF R+SQ+ + +++ E D
Sbjct: 25 GTVAYIGATLFASGKWVGVILDEAKGKNDGTVQGKRYFTCEENHGIFVRQSQIQLMDDGGSSATSPETPD 94
BLAST of Centrosome-associated protein 350 vs. Ensembl Zebrafish
Match: dctn1a (dynactin 1a [Source:ZFIN;Acc:ZDB-GENE-070117-2205]) HSP 1 Score: 114.775 bits (286), Expect = 4.621e-25 Identity = 160/738 (21.68%), Postives = 347/738 (47.02%), Query Frame = 1
Query: 1228 LEKLNNELQRELLDAKEREERIKKEFDSYRDMMRSGEEEIEMITIDKEMAEEKLEQVNQDYRNLKKLYEQVLEENSML------KNSDGTSDAKIFIDQTSTIN-KYKNALLELSQSINCYKEENRNL-------NSELDILKELQIFQENESEQLKSKIEKHEKDLKEMKDLVDSTADVEVILDKLTFKNXXXXXXXXXXXXXXXXXXXXXXXXXXVIESKDKKIREFHEECDCLNLIVNEIQNALDKKKIENSELLKTTNQMNERICXXXXXXXXXXXXXXXXXXXVKKAKAKDRELSSLTFSKQNIEKNEMKRDIENKLKTIEISHKSHQVQLLIQYLPASFSLPGGEHDLIETVQIVDKLIDKISLVLEYIIQKRRL----YQQRDNSEKTPENICIQYKLEFLLLIWCGLLKQLQINIHHSSPEALCQLRSEFKQILQQEQNIDLLIDLMKKQCLDNSRNFSGVLQSIAFFQNFYADRFCYQQIDCNLKMENFISILSKGSECLRNDLSWIDQMLE-NNVGEQTLKLMDNLN-----------KISTNVQST-MKNTQMYLRHNQRITFDSSVS-KSIDGIIFSLMDIVLSISDFALQLTDERIFS-----DEAMCRLTEIFANNRNPLNPTSDNEILF-SLNSIDKQVENIVSNFKSGVYDADKLNKTFNSAIDTNATNYREKLMGLQALSFEIKLKDEMLALINQELKEKSSQLSEILMQVNFYKQKLQTA 3327
+++ N+LQ++L +AK+ + D Y + M + IEM T+DKEMAEE+ E + Q+ +LK+ E++ + +L K SDG + + + Q N + K AL+ + + K+E+ L NSEL+ L+ ++ E+L+ +++ E + E+K+ VD+ E +++ LT +N LE+++++L++ + +L+ + + E+ E+ + E E+ D V E Q ++ + ++ +T N+ E L +E + E +++ A EL F + E + IE +L+ +E+S + QV LL ++P SF GG+HD I + ++ +LI K L+ + +K L ++ E + L + L + L + ++ + + ++ + ++ E+++D LIDL+ K LD + + ++I ++Q+ Y+ C Q DC +++ + I +C+ +++ + L+ G + L+ +L+ KI + T LR +++++ + S K + ++ L ++ + + L ++ S D A + +++ LNP E L S +++ + + + + G YD+++ + ++T A R ++ + L +++ ++ ++ + + LK K +LSE ++++ ++KL T+
Sbjct: 214 MQEQQNDLQKQLKEAKKEAREALEAKDRYMEEMADTADAIEMATLDKEMAEERAESLQQETESLKEKLEELTMDMEILKHEIEEKGSDGAASS-YHVKQLEEQNARLKEALVRMRDLSSSEKQEHVKLQKQMEKKNSELETLR-------SQKEKLQEEMKLAEDTIDELKEQVDAALGAEEMVETLTERNLDLEEKVRELRETVSDLESINEMNDELQENARETELELREQLDLAGARVREAQKRVEAAQETLADYQQTINKYRELTTHLQEVNRELTNQQSSSAEQLQQPAA---EL--FDFKIKFAETKAYAKAIEMELRKMEVSQANRQVSLLTSFMPESFLRHGGDHDCILVLLLIPRLICKAELISKQAQEKFDLTGGSLERAGLRGAAGEQLSFASGLVYSLTLLQATLHKYELALSVCGVDVYKRMGMLYSEMCVHERSLDFLIDLLHKDQLDETVQVEPLTKAIKYYQHLYSVHLCDQPEDCTVQLADHIKFTQSALDCMGSEVGRLRAFLQAGQEGAELCVLLKDLDTSCGDIRQFCKKIRRRMPGTDAPGIPAALRFSEQVSEALADSRKQLARVVAVLQEVSAAGAQMMAPLQEQEGLSAVKIEDVAFKAVEQVYGTQG--LNP---YECLRQSCSAVIATMNKMATAMQEGEYDSERPQRP-PPPVETRAAAVRAEMTDAEGLGNKLEDRETVIKELKKSLKIKGEELSEANVRLSLLEKKLDTS 932 HSP 2 Score: 67.0106 bits (162), Expect = 1.899e-10 Identity = 29/70 (41.43%), Postives = 42/70 (60.00%), Query Frame = 1
Query: 145 GTVRFIGSTASAKGTFYGIELHTADGRTDGTMDGISYFECKEKHGIFARRSQLTKIQSTEVTSSENEVHD 354
GTV +IG+T A G + G+ L A G+ DGT+ G YF C+E HGIF R+SQ+ + +++ E D
Sbjct: 25 GTVAYIGATLFASGKWVGVILDEAKGKNDGTVQGKRYFTCEENHGIFVRQSQIQLMDDGGSSATSPETPD 94
BLAST of Centrosome-associated protein 350 vs. Ensembl Zebrafish
Match: dctn1a (dynactin 1a [Source:ZFIN;Acc:ZDB-GENE-070117-2205]) HSP 1 Score: 100.138 bits (248), Expect = 1.428e-20 Identity = 160/777 (20.59%), Postives = 347/777 (44.66%), Query Frame = 1
Query: 1228 LEKLNNELQRELLDAKEREERIKKEFDSYRDMMRSGEEEIEMITIDKEMAEEKLEQVNQDYRNLKKLYEQVLEENSMLK---------------------------------------------NSDGTSDAKIFIDQTSTIN-KYKNALLELSQSINCYKEENRNL-------NSELDILKELQIFQENESEQLKSKIEKHEKDLKEMKDLVDSTADVEVILDKLTFKNXXXXXXXXXXXXXXXXXXXXXXXXXXVIESKDKKIREFHEECDCLNLIVNEIQNALDKKKIENSELLKTTNQMNERICXXXXXXXXXXXXXXXXXXXVKKAKAKDRELSSLTFSKQNIEKNEMKRDIENKLKTIEISHKSHQVQLLIQYLPASFSLPGGEHDLIETVQIVDKLIDKISLVLEYIIQKRRL----YQQRDNSEKTPENICIQYKLEFLLLIWCGLLKQLQINIHHSSPEALCQLRSEFKQILQQEQNIDLLIDLMKKQCLDNSRNFSGVLQSIAFFQNFYADRFCYQQIDCNLKMENFISILSKGSECLRNDLSWIDQMLE-NNVGEQTLKLMDNLN-----------KISTNVQST-MKNTQMYLRHNQRITFDSSVS-KSIDGIIFSLMDIVLSISDFALQLTDERIFS-----DEAMCRLTEIFANNRNPLNPTSDNEILF-SLNSIDKQVENIVSNFKSGVYDADKLNKTFNSAIDTNATNYREKLMGLQALSFEIKLKDEMLALINQELKEKSSQLSEILMQVNFYKQKLQTA 3327
+++ N+LQ++L +AK+ + D Y + M + IEM T+DKEMAEE+ E + Q+ +LK+ E++ + +LK SDG + + + Q N + K AL+ + + K+E+ L NSEL+ L+ ++ E+L+ +++ E + E+K+ VD+ E +++ LT +N LE+++++L++ + +L+ + + E+ E+ + E E+ D V E Q ++ + ++ +T N+ E L +E + E +++ A EL F + E + IE +L+ +E+S + QV LL ++P SF GG+HD I + ++ +LI K L+ + +K L ++ E + L + L + L + ++ + + ++ + ++ E+++D LIDL+ K LD + + ++I ++Q+ Y+ C Q DC +++ + I +C+ +++ + L+ G + L+ +L+ KI + T LR +++++ + S K + ++ L ++ + + L ++ S D A + +++ LNP E L S +++ + + + + G YD+++ + ++T A R ++ + L +++ ++ ++ + + LK K +LSE ++++ ++KL T+
Sbjct: 214 MQEQQNDLQKQLKEAKKEAREALEAKDRYMEEMADTADAIEMATLDKEMAEERAESLQQETESLKEKLEELTMDMEILKHEIEEKGENMHTNIHRLITTDPSCWSFRCLTSMCVCSFVCVCVFSGSDGAASS-YHVKQLEEQNARLKEALVRMRDLSSSEKQEHVKLQKQMEKKNSELETLR-------SQKEKLQEEMKLAEDTIDELKEQVDAALGAEEMVETLTERNLDLEEKVRELRETVSDLESINEMNDELQENARETELELREQLDLAGARVREAQKRVEAAQETLADYQQTINKYRELTTHLQEVNRELTNQQSSSAEQLQQPAA---EL--FDFKIKFAETKAYAKAIEMELRKMEVSQANRQVSLLTSFMPESFLRHGGDHDCILVLLLIPRLICKAELISKQAQEKFDLTGGSLERAGLRGAAGEQLSFASGLVYSLTLLQATLHKYELALSVCGVDVYKRMGMLYSEMCVHERSLDFLIDLLHKDQLDETVQVEPLTKAIKYYQHLYSVHLCDQPEDCTVQLADHIKFTQSALDCMGSEVGRLRAFLQAGQEGAELCVLLKDLDTSCGDIRQFCKKIRRRMPGTDAPGIPAALRFSEQVSEALADSRKQLARVVAVLQEVSAAGAQMMAPLQEQEGLSAVKIEDVAFKAVEQVYGTQG--LNP---YECLRQSCSAVIATMNKMATAMQEGEYDSERPQRP-PPPVETRAAAVRAEMTDAEGLGNKLEDRETVIKELKKSLKIKGEELSEANVRLSLLEKKLDTS 971 HSP 2 Score: 66.6254 bits (161), Expect = 1.999e-10 Identity = 29/70 (41.43%), Postives = 42/70 (60.00%), Query Frame = 1
Query: 145 GTVRFIGSTASAKGTFYGIELHTADGRTDGTMDGISYFECKEKHGIFARRSQLTKIQSTEVTSSENEVHD 354
GTV +IG+T A G + G+ L A G+ DGT+ G YF C+E HGIF R+SQ+ + +++ E D
Sbjct: 25 GTVAYIGATLFASGKWVGVILDEAKGKNDGTVQGKRYFTCEENHGIFVRQSQIQLMDDGGSSATSPETPD 94
BLAST of Centrosome-associated protein 350 vs. Ensembl Zebrafish
Match: dctn1b (dynactin 1b [Source:ZFIN;Acc:ZDB-GENE-050419-28]) HSP 1 Score: 97.8265 bits (242), Expect = 6.854e-20 Identity = 167/786 (21.25%), Postives = 336/786 (42.75%), Query Frame = 1
Query: 1186 LQILKKKEYKRCGDLEKLNNELQRELLDAKEREERIKKEFDSYRDMMRSGEEEIEMITIDKEMAEEKLEQVNQDYRNLKKLYEQVLEENSML------KNSDGTSDAKIFIDQTSTIN-KYKNALLELSQSINCYKEEN-------RNLNSELDILKELQIFQENESEQLKSKIEKHEKDLKEMKDLVDSTADVEVILDKLTFKNXXXXXXXXXXXXXXXXXXXXXXXXXXVIESKDKKIREFHEECDCLNLIVNEIQNALDKKKIENSELL----KTTNQMNERICXXXXXXXXXXXXXXXXXXXVKKAKAKDRELSS---------------LTFSKQNIEKNEMKRDIENKLKTIEISHKSHQVQLLIQYLPASFSLPGGEHDLIETVQIVDKLIDKISLVLEYIIQKRRLYQQRDNSEKTPENICIQYKLEFLL-LIWCGLLKQLQINIH-------HSSPEALCQLRSEFKQILQQEQNIDLLIDLMKKQCLDNSRNFSGVLQSIAFFQNFYADRFCYQQIDCNLKMENFISILSKGSECLRNDLSWIDQMLENNVGEQTL-KLMDNLNKISTNVQSTMKNTQMYLRHNQRITFDSSVSKSIDGIIFSLMDIVLSISDFALQ-LTDERIFSDEAMCRLTEIFANNRNPLNPTSDNEILFSLNSID---KQVENI--------------------------VSNFKSGVYDADKLNKTFNSAIDTNATNYREKLMGLQALSFEIKLKDEMLALINQELKEKSSQLSEILMQVNFYKQKLQTA 3327
+Q+ + +E+K +++ NELQ++L +AK + + + Y + M + IEM T+DKEMAEE+ E + + LK+ +++ + +L K SDG + + + Q N + K AL+ + K+E+ N ELD L+ E+L+ +++ EK + E+K+ VD++ E +++ LT +N +E K +++RE + + +N + +E+Q + ++E E L + +R+ + + + IQK E+ + +REL S F + E + IE +L+ +E+ + QV LLI ++P SF G+HD I + ++ +LI K L+ + +K L + S+K + +L F LI+ L LQ +H S + ++ S + ++ E+++D LIDL+ K LD + N + ++I ++Q+ Y+ Q DC +++ + I +C+ ++ + ++ E+ L+ +L+ ++++ F + + + G + LS + L D R L E+ A + P S++E L ++ D K E I + + G YD+D+ +T S ++ A R ++ + L +++ ++ ++ + + LK K +LSE ++++ ++KL +A
Sbjct: 216 IQLEQLQEWK--SKMQEQQNELQKQLKEAKREAKEALEAKERYMEEMADTADAIEMATLDKEMAEERAESLQLEADALKERVDELTMDLEILKHEIEEKGSDGAASS-YHVKQLEEQNARLKEALVRMRDLSASEKQEHGKQQKLMEKKNFELDALR-------CHKEKLQEEMKMAEKTIDELKEQVDASLGAEEMVEMLTERNLD-------------------------LEEKVRELRETVADLEAINEMNDELQENARETELELREQLDLGAAGVREAEKRVEAAQETVADYQQTIQKYRELTANLQEVNRELMSQQEANSEQQQQPAEIFDFKIKFAETKAYAKAIEMELRKMEVIQANRQVSLLISFMPDSFLKHRGDHDCILALLLIPRLICKSELISKQAQEKFELTE--SCSQKPGMRGAVGERLSFAAGLIYS--LTLLQAALHKYEHALSQCSVDVYKRVGSLYSELSVHERSLDFLIDLLYKDLLDETVNVEPLTKAIKYYQHLYSIHLAEQPEDCTMQLADHIRFTQSALDCMAVEVGRLRAFIQTGQDEEAFCVLLKDLDTSCSDIRQ----------------FCKKIRRRMPGTDAPGIPAALSFGPQVCEALADSRRQLAWVNAVLQEVAAAAAQLIAPLSEHEGLPAVKLEDMAFKAAEQIYGSQGINAQECLRQSCSVVIATMNKMATAMQEGEYDSDR-PQTGISPVEVRAAALRAEITDAEGLGLKLEDRETVIKELKKSLKIKGEELSEANVRLSLLEKKLDSA 945 HSP 2 Score: 64.3142 bits (155), Expect = 1.181e-9 Identity = 28/64 (43.75%), Postives = 40/64 (62.50%), Query Frame = 1
Query: 145 GTVRFIGSTASAKGTFYGIELHTADGRTDGTMDGISYFECKEKHGIFARRSQLTKIQSTEVTSS 336
GTV +IG+T A G + G+ L G+ DGT+ G YF C+E HGIF R+SQ+ ++ T+S
Sbjct: 25 GTVAYIGNTLFASGKWVGVILDEPKGKNDGTVQGKRYFLCQENHGIFVRQSQIQLVEDGADTTS 88
BLAST of Centrosome-associated protein 350 vs. Ensembl Xenopus
Match: ENSXETT00000000206.1 (dynactin subunit 1 [Source:NCBI gene;Acc:447948]) HSP 1 Score: 98.9821 bits (245), Expect = 4.061e-20 Identity = 150/746 (20.11%), Postives = 305/746 (40.88%), Query Frame = 1
Query: 1312 YRDMMRSGEEEIEMITIDKEMAEEKLEQVNQDYRNLK----------KLYEQVLEENSMLKNSDGTSDAKIFIDQTSTINKYKNALLELSQSINCYKEENRNL-------NSELDILKELQIFQENESEQLKSKIEKHEKDLKEMKDLVDSTADVEVILDKLTFKNXXXXXXXXXXXXXXXXXXXXXXXXXXVIESKDKKIREFHEECDCLNLIVNEIQNALDKKKIENSELLKTTNQMNERICXXXXXXXXXXXXXXXXXXXVKKAK-------AKDREL---SSLTFSKQNIEKNEM-------------KRDIENKLKTIEISHKSHQVQLLIQYLPASFSLPGGEHDLIETVQIVDKLIDKISLVLEYIIQKRRLY----QQRDNSEKTPENICIQYKLEFLLLIWCGLLKQLQINIHHSSPEALCQLRSEFKQILQQEQNIDLLIDLMKKQCLDNSRNFSGVLQSIAFFQNFYADRFCYQQIDCNLKMENFISILSKGSECLRNDLSWIDQMLENNVGEQTLKLMDNLNKISTNVQSTMKNTQMYLRHNQRITFDSSVSKSIDGIIFSLMDIVLSISDFALQ-LTDERIFSDEAMCRLTEIFANNRNPLNPTSDNEILFSLNSID---KQVENI--------------------------VSNFKSGVYDADKLNKTFNSAIDTNATNYREKLMGLQALSFEIKLKDEMLALINQELKEKSSQLSEILMQVNFYKQKLQTA 3327
Y + M + IEM T+DKEMAEE+ E + Q+ LK ++++ +EE K SDG + + + K AL+ + K+E+ + N+ELD L++ + E+L+ + EK + E+K+ VD+ E +++ LT +N +E K +++RE + + +N + +E+Q + ++E E L + R+ ++ + + + +KK + +REL + K+ EM + IE +L+ +E+S + V LL ++P SF GG+HD I + ++ +LI K L+ + +K L Q+ E + L + L + L + + + S E ++ + ++ E+++D LI+L+ K LD + N + ++I ++Q+ Y+ Q +C +++ + I +C+ ++S + L +VG+++ L + T+ + F + + + G + + LS + + L D R + + E+ A + P +NE L +L D K E I + + G YDA+K ++ A R ++ + L +++ ++ ++ + + LK K +LSE ++++ ++KL +A
Sbjct: 282 YMEEMADTADAIEMATLDKEMAEERAESLQQEVDTLKDKVEELKIDLEIFKHEIEE----KGSDGAASSYQVKQLEEQNARLKEALVRMRDLSASEKQEHVKVQKQMEKKNTELDTLRQ-------QKEKLQEEASLMEKTIDELKEQVDAALGAEEMVETLTERNLD-------------------------LEEKVRELRETVSDLEAINEMNDELQENARETELELREQL---DMAGARVREAEKRVEAAQETVADYQQTIKKYRDLTAHLQEVNRELRNQQEASVEKEQQPSPEMFDFKIKFAETKAHAKAIEMELRKMEVSQANRHVSLLTSFMPDSFLRHGGDHDCILVLLLIPRLICKAELISKQAQEKFELSEASEQKSGMRGAVGEQMSFAAGLVYSLTLLQATLHKYEQALDKCSVEVYKKVGMLYPEMSVHERSLDFLIELLHKDQLDETVNVEPLTKAIKYYQHLYSIHLADQSEECTMQLSDHIKFTQSALDCMGVEVSRLRAFL--HVGQESSDFAILLKDLETSCSDIRQ-------------FCKKIRRRMPGTEAAGIPAALSFAQPVCETLLDCRKYLKCVVAVFQEVAAAGAQMIAPMGENEGLQALKLEDVAFKATEQIYGSKGSNPYECLRQSCSVVIATMNKMATAMQEGEYDAEKPQSKSPPPVEQRAAALRAEITDAEGLGLKLEDRETVIKELKKSLKIKGEELSEANVRLSLLEKKLDSA 973 HSP 2 Score: 66.2402 bits (160), Expect = 4.108e-10 Identity = 30/79 (37.97%), Postives = 46/79 (58.23%), Query Frame = 1
Query: 103 FQIGDSV-LYNSKLEGTVRFIGSTASAKGTFYGIELHTADGRTDGTMDGISYFECKEKHGIFARRSQLTKIQSTEVTSS 336
++G V + GTV ++G+T A G + G+ L + G+ DGT+ G YF C+E HGIF R+SQ+ I+ T+S
Sbjct: 28 LKVGSRVEVIGKGYRGTVAYVGATLFATGKWVGVILDDSKGKNDGTVQGRRYFTCEENHGIFVRQSQIQVIEDGADTTS 106
BLAST of Centrosome-associated protein 350 vs. Ensembl Xenopus
Match: ENSXETT00000028179.1 (dynactin subunit 1 [Source:NCBI gene;Acc:447948]) HSP 1 Score: 98.5969 bits (244), Expect = 4.879e-20 Identity = 150/746 (20.11%), Postives = 305/746 (40.88%), Query Frame = 1
Query: 1312 YRDMMRSGEEEIEMITIDKEMAEEKLEQVNQDYRNLK----------KLYEQVLEENSMLKNSDGTSDAKIFIDQTSTINKYKNALLELSQSINCYKEENRNL-------NSELDILKELQIFQENESEQLKSKIEKHEKDLKEMKDLVDSTADVEVILDKLTFKNXXXXXXXXXXXXXXXXXXXXXXXXXXVIESKDKKIREFHEECDCLNLIVNEIQNALDKKKIENSELLKTTNQMNERICXXXXXXXXXXXXXXXXXXXVKKAK-------AKDREL---SSLTFSKQNIEKNEM-------------KRDIENKLKTIEISHKSHQVQLLIQYLPASFSLPGGEHDLIETVQIVDKLIDKISLVLEYIIQKRRLY----QQRDNSEKTPENICIQYKLEFLLLIWCGLLKQLQINIHHSSPEALCQLRSEFKQILQQEQNIDLLIDLMKKQCLDNSRNFSGVLQSIAFFQNFYADRFCYQQIDCNLKMENFISILSKGSECLRNDLSWIDQMLENNVGEQTLKLMDNLNKISTNVQSTMKNTQMYLRHNQRITFDSSVSKSIDGIIFSLMDIVLSISDFALQ-LTDERIFSDEAMCRLTEIFANNRNPLNPTSDNEILFSLNSID---KQVENI--------------------------VSNFKSGVYDADKLNKTFNSAIDTNATNYREKLMGLQALSFEIKLKDEMLALINQELKEKSSQLSEILMQVNFYKQKLQTA 3327
Y + M + IEM T+DKEMAEE+ E + Q+ LK ++++ +EE K SDG + + + K AL+ + K+E+ + N+ELD L++ + E+L+ + EK + E+K+ VD+ E +++ LT +N +E K +++RE + + +N + +E+Q + ++E E L + R+ ++ + + + +KK + +REL + K+ EM + IE +L+ +E+S + V LL ++P SF GG+HD I + ++ +LI K L+ + +K L Q+ E + L + L + L + + + S E ++ + ++ E+++D LI+L+ K LD + N + ++I ++Q+ Y+ Q +C +++ + I +C+ ++S + L +VG+++ L + T+ + F + + + G + + LS + + L D R + + E+ A + P +NE L +L D K E I + + G YDA+K ++ A R ++ + L +++ ++ ++ + + LK K +LSE ++++ ++KL +A
Sbjct: 275 YMEEMADTADAIEMATLDKEMAEERAESLQQEVDTLKDKVEELKIDLEIFKHEIEE----KGSDGAASSYQVKQLEEQNARLKEALVRMRDLSASEKQEHVKVQKQMEKKNTELDTLRQ-------QKEKLQEEASLMEKTIDELKEQVDAALGAEEMVETLTERNLD-------------------------LEEKVRELRETVSDLEAINEMNDELQENARETELELREQL---DMAGARVREAEKRVEAAQETVADYQQTIKKYRDLTAHLQEVNRELRNQQEASVEKEQQPSPEMFDFKIKFAETKAHAKAIEMELRKMEVSQANRHVSLLTSFMPDSFLRHGGDHDCILVLLLIPRLICKAELISKQAQEKFELSEASEQKSGMRGAVGEQMSFAAGLVYSLTLLQATLHKYEQALDKCSVEVYKKVGMLYPEMSVHERSLDFLIELLHKDQLDETVNVEPLTKAIKYYQHLYSIHLADQSEECTMQLSDHIKFTQSALDCMGVEVSRLRAFL--HVGQESSDFAILLKDLETSCSDIRQ-------------FCKKIRRRMPGTEAAGIPAALSFAQPVCETLLDCRKYLKCVVAVFQEVAAAGAQMIAPMGENEGLQALKLEDVAFKATEQIYGSKGSNPYECLRQSCSVVIATMNKMATAMQEGEYDAEKPQSKSPPPVEQRAAALRAEITDAEGLGLKLEDRETVIKELKKSLKIKGEELSEANVRLSLLEKKLDSA 966 HSP 2 Score: 66.2402 bits (160), Expect = 3.833e-10 Identity = 30/79 (37.97%), Postives = 46/79 (58.23%), Query Frame = 1
Query: 103 FQIGDSV-LYNSKLEGTVRFIGSTASAKGTFYGIELHTADGRTDGTMDGISYFECKEKHGIFARRSQLTKIQSTEVTSS 336
++G V + GTV ++G+T A G + G+ L + G+ DGT+ G YF C+E HGIF R+SQ+ I+ T+S
Sbjct: 28 LKVGSRVEVIGKGYRGTVAYVGATLFATGKWVGVILDDSKGKNDGTVQGRRYFTCEENHGIFVRQSQIQVIEDGADTTS 106
BLAST of Centrosome-associated protein 350 vs. Ensembl Xenopus
Match: ENSXETT00000011502.1 (dynactin subunit 1 [Source:NCBI gene;Acc:447948]) HSP 1 Score: 98.5969 bits (244), Expect = 5.031e-20 Identity = 150/746 (20.11%), Postives = 305/746 (40.88%), Query Frame = 1
Query: 1312 YRDMMRSGEEEIEMITIDKEMAEEKLEQVNQDYRNLK----------KLYEQVLEENSMLKNSDGTSDAKIFIDQTSTINKYKNALLELSQSINCYKEENRNL-------NSELDILKELQIFQENESEQLKSKIEKHEKDLKEMKDLVDSTADVEVILDKLTFKNXXXXXXXXXXXXXXXXXXXXXXXXXXVIESKDKKIREFHEECDCLNLIVNEIQNALDKKKIENSELLKTTNQMNERICXXXXXXXXXXXXXXXXXXXVKKAK-------AKDREL---SSLTFSKQNIEKNEM-------------KRDIENKLKTIEISHKSHQVQLLIQYLPASFSLPGGEHDLIETVQIVDKLIDKISLVLEYIIQKRRLY----QQRDNSEKTPENICIQYKLEFLLLIWCGLLKQLQINIHHSSPEALCQLRSEFKQILQQEQNIDLLIDLMKKQCLDNSRNFSGVLQSIAFFQNFYADRFCYQQIDCNLKMENFISILSKGSECLRNDLSWIDQMLENNVGEQTLKLMDNLNKISTNVQSTMKNTQMYLRHNQRITFDSSVSKSIDGIIFSLMDIVLSISDFALQ-LTDERIFSDEAMCRLTEIFANNRNPLNPTSDNEILFSLNSID---KQVENI--------------------------VSNFKSGVYDADKLNKTFNSAIDTNATNYREKLMGLQALSFEIKLKDEMLALINQELKEKSSQLSEILMQVNFYKQKLQTA 3327
Y + M + IEM T+DKEMAEE+ E + Q+ LK ++++ +EE K SDG + + + K AL+ + K+E+ + N+ELD L++ + E+L+ + EK + E+K+ VD+ E +++ LT +N +E K +++RE + + +N + +E+Q + ++E E L + R+ ++ + + + +KK + +REL + K+ EM + IE +L+ +E+S + V LL ++P SF GG+HD I + ++ +LI K L+ + +K L Q+ E + L + L + L + + + S E ++ + ++ E+++D LI+L+ K LD + N + ++I ++Q+ Y+ Q +C +++ + I +C+ ++S + L +VG+++ L + T+ + F + + + G + + LS + + L D R + + E+ A + P +NE L +L D K E I + + G YDA+K ++ A R ++ + L +++ ++ ++ + + LK K +LSE ++++ ++KL +A
Sbjct: 288 YMEEMADTADAIEMATLDKEMAEERAESLQQEVDTLKDKVEELKIDLEIFKHEIEE----KGSDGAASSYQVKQLEEQNARLKEALVRMRDLSASEKQEHVKVQKQMEKKNTELDTLRQ-------QKEKLQEEASLMEKTIDELKEQVDAALGAEEMVETLTERNLD-------------------------LEEKVRELRETVSDLEAINEMNDELQENARETELELREQL---DMAGARVREAEKRVEAAQETVADYQQTIKKYRDLTAHLQEVNRELRNQQEASVEKEQQPSPEMFDFKIKFAETKAHAKAIEMELRKMEVSQANRHVSLLTSFMPDSFLRHGGDHDCILVLLLIPRLICKAELISKQAQEKFELSEASEQKSGMRGAVGEQMSFAAGLVYSLTLLQATLHKYEQALDKCSVEVYKKVGMLYPEMSVHERSLDFLIELLHKDQLDETVNVEPLTKAIKYYQHLYSIHLADQSEECTMQLSDHIKFTQSALDCMGVEVSRLRAFL--HVGQESSDFAILLKDLETSCSDIRQ-------------FCKKIRRRMPGTEAAGIPAALSFAQPVCETLLDCRKYLKCVVAVFQEVAAAGAQMIAPMGENEGLQALKLEDVAFKATEQIYGSKGSNPYECLRQSCSVVIATMNKMATAMQEGEYDAEKPQSKSPPPVEQRAAALRAEITDAEGLGLKLEDRETVIKELKKSLKIKGEELSEANVRLSLLEKKLDSA 979 HSP 2 Score: 66.2402 bits (160), Expect = 3.844e-10 Identity = 31/82 (37.80%), Postives = 47/82 (57.32%), Query Frame = 1
Query: 103 FQIGDSV-LYNSKLEGTVRFIGSTASAKGTFYGIELHTADGRTDGTMDGISYFECKEKHGIFARRSQLTKIQ-STEVTSSEN 342
++G V + GTV ++G+T A G + G+ L + G+ DGT+ G YF C+E HGIF R+SQ+ I+ + TS E
Sbjct: 28 LKVGSRVEVIGKGYRGTVAYVGATLFATGKWVGVILDDSKGKNDGTVQGRRYFTCEENHGIFVRQSQIQVIEDGADTTSPET 109
BLAST of Centrosome-associated protein 350 vs. Ensembl Xenopus
Match: ENSXETT00000028089.1 (dynactin subunit 1 [Source:NCBI gene;Acc:447948]) HSP 1 Score: 98.5969 bits (244), Expect = 5.076e-20 Identity = 150/746 (20.11%), Postives = 305/746 (40.88%), Query Frame = 1
Query: 1312 YRDMMRSGEEEIEMITIDKEMAEEKLEQVNQDYRNLK----------KLYEQVLEENSMLKNSDGTSDAKIFIDQTSTINKYKNALLELSQSINCYKEENRNL-------NSELDILKELQIFQENESEQLKSKIEKHEKDLKEMKDLVDSTADVEVILDKLTFKNXXXXXXXXXXXXXXXXXXXXXXXXXXVIESKDKKIREFHEECDCLNLIVNEIQNALDKKKIENSELLKTTNQMNERICXXXXXXXXXXXXXXXXXXXVKKAK-------AKDREL---SSLTFSKQNIEKNEM-------------KRDIENKLKTIEISHKSHQVQLLIQYLPASFSLPGGEHDLIETVQIVDKLIDKISLVLEYIIQKRRLY----QQRDNSEKTPENICIQYKLEFLLLIWCGLLKQLQINIHHSSPEALCQLRSEFKQILQQEQNIDLLIDLMKKQCLDNSRNFSGVLQSIAFFQNFYADRFCYQQIDCNLKMENFISILSKGSECLRNDLSWIDQMLENNVGEQTLKLMDNLNKISTNVQSTMKNTQMYLRHNQRITFDSSVSKSIDGIIFSLMDIVLSISDFALQ-LTDERIFSDEAMCRLTEIFANNRNPLNPTSDNEILFSLNSID---KQVENI--------------------------VSNFKSGVYDADKLNKTFNSAIDTNATNYREKLMGLQALSFEIKLKDEMLALINQELKEKSSQLSEILMQVNFYKQKLQTA 3327
Y + M + IEM T+DKEMAEE+ E + Q+ LK ++++ +EE K SDG + + + K AL+ + K+E+ + N+ELD L++ + E+L+ + EK + E+K+ VD+ E +++ LT +N +E K +++RE + + +N + +E+Q + ++E E L + R+ ++ + + + +KK + +REL + K+ EM + IE +L+ +E+S + V LL ++P SF GG+HD I + ++ +LI K L+ + +K L Q+ E + L + L + L + + + S E ++ + ++ E+++D LI+L+ K LD + N + ++I ++Q+ Y+ Q +C +++ + I +C+ ++S + L +VG+++ L + T+ + F + + + G + + LS + + L D R + + E+ A + P +NE L +L D K E I + + G YDA+K ++ A R ++ + L +++ ++ ++ + + LK K +LSE ++++ ++KL +A
Sbjct: 289 YMEEMADTADAIEMATLDKEMAEERAESLQQEVDTLKDKVEELKIDLEIFKHEIEE----KGSDGAASSYQVKQLEEQNARLKEALVRMRDLSASEKQEHVKVQKQMEKKNTELDTLRQ-------QKEKLQEEASLMEKTIDELKEQVDAALGAEEMVETLTERNLD-------------------------LEEKVRELRETVSDLEAINEMNDELQENARETELELREQL---DMAGARVREAEKRVEAAQETVADYQQTIKKYRDLTAHLQEVNRELRNQQEASVEKEQQPSPEMFDFKIKFAETKAHAKAIEMELRKMEVSQANRHVSLLTSFMPDSFLRHGGDHDCILVLLLIPRLICKAELISKQAQEKFELSEASEQKSGMRGAVGEQMSFAAGLVYSLTLLQATLHKYEQALDKCSVEVYKKVGMLYPEMSVHERSLDFLIELLHKDQLDETVNVEPLTKAIKYYQHLYSIHLADQSEECTMQLSDHIKFTQSALDCMGVEVSRLRAFL--HVGQESSDFAILLKDLETSCSDIRQ-------------FCKKIRRRMPGTEAAGIPAALSFAQPVCETLLDCRKYLKCVVAVFQEVAAAGAQMIAPMGENEGLQALKLEDVAFKATEQIYGSKGSNPYECLRQSCSVVIATMNKMATAMQEGEYDAEKPQSKSPPPVEQRAAALRAEITDAEGLGLKLEDRETVIKELKKSLKIKGEELSEANVRLSLLEKKLDSA 980 HSP 2 Score: 66.2402 bits (160), Expect = 4.011e-10 Identity = 31/82 (37.80%), Postives = 47/82 (57.32%), Query Frame = 1
Query: 103 FQIGDSV-LYNSKLEGTVRFIGSTASAKGTFYGIELHTADGRTDGTMDGISYFECKEKHGIFARRSQLTKIQ-STEVTSSEN 342
++G V + GTV ++G+T A G + G+ L + G+ DGT+ G YF C+E HGIF R+SQ+ I+ + TS E
Sbjct: 28 LKVGSRVEVIGKGYRGTVAYVGATLFATGKWVGVILDDSKGKNDGTVQGRRYFTCEENHGIFVRQSQIQVIEDGADTTSPET 109
BLAST of Centrosome-associated protein 350 vs. Ensembl Xenopus
Match: ENSXETT00000011652.1 (dynactin subunit 1 [Source:NCBI gene;Acc:447948]) HSP 1 Score: 98.5969 bits (244), Expect = 5.354e-20 Identity = 150/746 (20.11%), Postives = 305/746 (40.88%), Query Frame = 1
Query: 1312 YRDMMRSGEEEIEMITIDKEMAEEKLEQVNQDYRNLK----------KLYEQVLEENSMLKNSDGTSDAKIFIDQTSTINKYKNALLELSQSINCYKEENRNL-------NSELDILKELQIFQENESEQLKSKIEKHEKDLKEMKDLVDSTADVEVILDKLTFKNXXXXXXXXXXXXXXXXXXXXXXXXXXVIESKDKKIREFHEECDCLNLIVNEIQNALDKKKIENSELLKTTNQMNERICXXXXXXXXXXXXXXXXXXXVKKAK-------AKDREL---SSLTFSKQNIEKNEM-------------KRDIENKLKTIEISHKSHQVQLLIQYLPASFSLPGGEHDLIETVQIVDKLIDKISLVLEYIIQKRRLY----QQRDNSEKTPENICIQYKLEFLLLIWCGLLKQLQINIHHSSPEALCQLRSEFKQILQQEQNIDLLIDLMKKQCLDNSRNFSGVLQSIAFFQNFYADRFCYQQIDCNLKMENFISILSKGSECLRNDLSWIDQMLENNVGEQTLKLMDNLNKISTNVQSTMKNTQMYLRHNQRITFDSSVSKSIDGIIFSLMDIVLSISDFALQ-LTDERIFSDEAMCRLTEIFANNRNPLNPTSDNEILFSLNSID---KQVENI--------------------------VSNFKSGVYDADKLNKTFNSAIDTNATNYREKLMGLQALSFEIKLKDEMLALINQELKEKSSQLSEILMQVNFYKQKLQTA 3327
Y + M + IEM T+DKEMAEE+ E + Q+ LK ++++ +EE K SDG + + + K AL+ + K+E+ + N+ELD L++ + E+L+ + EK + E+K+ VD+ E +++ LT +N +E K +++RE + + +N + +E+Q + ++E E L + R+ ++ + + + +KK + +REL + K+ EM + IE +L+ +E+S + V LL ++P SF GG+HD I + ++ +LI K L+ + +K L Q+ E + L + L + L + + + S E ++ + ++ E+++D LI+L+ K LD + N + ++I ++Q+ Y+ Q +C +++ + I +C+ ++S + L +VG+++ L + T+ + F + + + G + + LS + + L D R + + E+ A + P +NE L +L D K E I + + G YDA+K ++ A R ++ + L +++ ++ ++ + + LK K +LSE ++++ ++KL +A
Sbjct: 295 YMEEMADTADAIEMATLDKEMAEERAESLQQEVDTLKDKVEELKIDLEIFKHEIEE----KGSDGAASSYQVKQLEEQNARLKEALVRMRDLSASEKQEHVKVQKQMEKKNTELDTLRQ-------QKEKLQEEASLMEKTIDELKEQVDAALGAEEMVETLTERNLD-------------------------LEEKVRELRETVSDLEAINEMNDELQENARETELELREQL---DMAGARVREAEKRVEAAQETVADYQQTIKKYRDLTAHLQEVNRELRNQQEASVEKEQQPSPEMFDFKIKFAETKAHAKAIEMELRKMEVSQANRHVSLLTSFMPDSFLRHGGDHDCILVLLLIPRLICKAELISKQAQEKFELSEASEQKSGMRGAVGEQMSFAAGLVYSLTLLQATLHKYEQALDKCSVEVYKKVGMLYPEMSVHERSLDFLIELLHKDQLDETVNVEPLTKAIKYYQHLYSIHLADQSEECTMQLSDHIKFTQSALDCMGVEVSRLRAFL--HVGQESSDFAILLKDLETSCSDIRQ-------------FCKKIRRRMPGTEAAGIPAALSFAQPVCETLLDCRKYLKCVVAVFQEVAAAGAQMIAPMGENEGLQALKLEDVAFKATEQIYGSKGSNPYECLRQSCSVVIATMNKMATAMQEGEYDAEKPQSKSPPPVEQRAAALRAEITDAEGLGLKLEDRETVIKELKKSLKIKGEELSEANVRLSLLEKKLDSA 986 HSP 2 Score: 66.2402 bits (160), Expect = 3.628e-10 Identity = 31/82 (37.80%), Postives = 47/82 (57.32%), Query Frame = 1
Query: 103 FQIGDSV-LYNSKLEGTVRFIGSTASAKGTFYGIELHTADGRTDGTMDGISYFECKEKHGIFARRSQLTKIQ-STEVTSSEN 342
++G V + GTV ++G+T A G + G+ L + G+ DGT+ G YF C+E HGIF R+SQ+ I+ + TS E
Sbjct: 28 LKVGSRVEVIGKGYRGTVAYVGATLFATGKWVGVILDDSKGKNDGTVQGRRYFTCEENHGIFVRQSQIQVIEDGADTTSPET 109
BLAST of Centrosome-associated protein 350 vs. Ensembl Mouse
Match: Dctn1 (dynactin 1 [Source:MGI Symbol;Acc:MGI:107745]) HSP 1 Score: 100.523 bits (249), Expect = 1.120e-20 Identity = 161/800 (20.12%), Postives = 343/800 (42.88%), Query Frame = 1
Query: 1186 LQILKKKEYKRCGDLEKLNNELQRELLDAKEREERIKKEFDSYRDMMRSGEEEIEMITIDKEMAEEKLEQVNQDYRNLKKLYEQVLEENSMLK------NSDGTSDAKIFIDQTSTINKYKNALLELSQSINCYKEENRNL-------NSELDILKELQIFQENESEQLKSKIEKHEKDLKEMKDLVDSTADVEVILDKLTFKNXXXXXXXXXXXXXXXXXXXXXXXXXXVIESKDKKIREFHEECDCLNLIVNEIQNALDKKKIENSELLKTTNQMNERICXXXXXXXXXXXXXXXXXXXVKK-----AKAKD--RELS----------------SLTFSKQNIEKNEMKRDIENKLKTIEISHKSHQVQLLIQYLPASFSLPGGEHDLIETVQIVDKLIDKISLVLEYIIQKRRLYQQRDNSEKTPENICIQYKLEFLLLIWCGL---LKQLQINIHHSSPEALCQ--------LRSEFKQILQQEQNIDLLIDLMKKQCLDNSRNFSGVLQSIAFFQNFYADRFCYQQIDCNLKMENFISILSKGSECLRNDLSWIDQMLENNVGEQTLKLMDNLNKISTNVQSTMKNTQMYLRH---------NQRITFDSSVS-------KSIDGIIFSLMDIVLSISDFALQLTDERIFSDEAMCRLT-----EIFANNRNPLNPTSDNEILF-SLNSIDKQVENIVSNFKSGVYDADKLNKTFNSAIDTNATNYREKLMGLQALSFEIKLKDEMLALINQELKEKSSQLSEILMQVNFYKQKLQTAVESREIIINQLNQRIYE 3378
+Q K K ++ DL++ E ++E +A E +ER Y + M + IEM T+DKEMAEE+ E + Q+ LK+ +++ + +LK SDG + + + K+AL+ + + K+E+ L N EL+++++ + E+L+ ++ + E + E+K+ VD+ E +++ LT +N +E K +++RE + + +N + +E+Q + ++E E L + R+ ++ + + + +KK A +D REL+ + F + E + IE +L+ +E++ + + LL ++P SF PGG+HD + + ++ +LI K L+ +++ ++ D SE E ++ L GL L LQ +H AL Q + S + ++ E+++D LI+L+ K LD + N + ++I ++Q+ Y+ Q D +++ + I +C+ ++ + L+ G++ + L + T+ T + + R + F S VS K + ++ L ++ + + L + A+ L +I+ + +S E L S + + + + + G YDA++ + ++ A R ++ + L +++ ++ ++ + + LK K +LSE ++++ ++KL +A + + I ++ R+ E
Sbjct: 241 VQEWKSKMQEQQADLQRRLKEARKEAKEALEAKER-------YMEEMADTADAIEMATLDKEMAEERAESLQQEVEALKERVDELTTDLEILKAEIEEKGSDGAASSYQLKQLEEQNARLKDALVRMRDLSSSEKQEHVKLQKLMEKKNQELEVVRQ-------QRERLQEELSQAESTIDELKEQVDAALGAEEMVEMLTDRNLN-------------------------LEEKVRELRETVGDLEAMNEMNDELQENARETELELREQL---DMAGARVREAQKRVEAAQETVADYQQTIKKYRQLTAHLQDVNRELTNQQEASVERQQQPPPETFDFKIKFAETKAHAKAIEMELRQMEVAQANRHMSLLTAFMPDSFLRPGGDHDCVLVLLLMPRLICKAELI------RKQAQEKFDLSENCSERPGLRGAAGEQLSFAAGLVYSLSLLQATLHRYE-HALSQCSVDVYKKVGSLYPEMSAHERSLDFLIELLHKDQLDETVNVEPLTKAIKYYQHLYSIHLAEQPEDSTMQLADHIKFTQSALDCMGVEVGRLRAFLQG--GQEATDIALLLRDLETSCSDTRQFCKKIRRRMPGTDAPGIPAALAFGSQVSDTLLDCRKHLTWVVAVLQEVAAAAAQLIAPLAENEGLPVAALEELAFKASEQIYGSPS-----SSPYECLRQSCTILISTMNKLATAMQEGEYDAER-PPSKPPPVELRAAALRAEITDAEGLGLKLEDRETVIKELKKSLKIKGEELSEANVRLSLLEKKLDSAAKDADERIEKVQTRLDE 983 HSP 2 Score: 65.0846 bits (157), Expect = 7.000e-10 Identity = 36/90 (40.00%), Postives = 50/90 (55.56%), Query Frame = 1
Query: 145 GTVRFIGSTASAKGTFYGIELHTADGRTDGTMDGISYFECKEKHGIFARRSQLTKIQ-STEVTSSE--NEVHDKLLNSCGETRDLTAQTS 405
GTV ++G+T A G + G+ L A G+ DGT+ G YF C E HGIF R+SQ+ + + TS E + K+L G D A+TS
Sbjct: 25 GTVAYVGATLFATGKWVGVILDEAKGKNDGTVQGRKYFTCDEGHGIFVRQSQIQVFEDGADTTSPETPDSSASKVLKREGA--DAAAKTS 112
BLAST of Centrosome-associated protein 350 vs. Ensembl Mouse
Match: Dctn1 (dynactin 1 [Source:MGI Symbol;Acc:MGI:107745]) HSP 1 Score: 100.138 bits (248), Expect = 1.282e-20 Identity = 161/800 (20.12%), Postives = 343/800 (42.88%), Query Frame = 1
Query: 1186 LQILKKKEYKRCGDLEKLNNELQRELLDAKEREERIKKEFDSYRDMMRSGEEEIEMITIDKEMAEEKLEQVNQDYRNLKKLYEQVLEENSMLK------NSDGTSDAKIFIDQTSTINKYKNALLELSQSINCYKEENRNL-------NSELDILKELQIFQENESEQLKSKIEKHEKDLKEMKDLVDSTADVEVILDKLTFKNXXXXXXXXXXXXXXXXXXXXXXXXXXVIESKDKKIREFHEECDCLNLIVNEIQNALDKKKIENSELLKTTNQMNERICXXXXXXXXXXXXXXXXXXXVKK-----AKAKD--RELS----------------SLTFSKQNIEKNEMKRDIENKLKTIEISHKSHQVQLLIQYLPASFSLPGGEHDLIETVQIVDKLIDKISLVLEYIIQKRRLYQQRDNSEKTPENICIQYKLEFLLLIWCGL---LKQLQINIHHSSPEALCQ--------LRSEFKQILQQEQNIDLLIDLMKKQCLDNSRNFSGVLQSIAFFQNFYADRFCYQQIDCNLKMENFISILSKGSECLRNDLSWIDQMLENNVGEQTLKLMDNLNKISTNVQSTMKNTQMYLRH---------NQRITFDSSVS-------KSIDGIIFSLMDIVLSISDFALQLTDERIFSDEAMCRLT-----EIFANNRNPLNPTSDNEILF-SLNSIDKQVENIVSNFKSGVYDADKLNKTFNSAIDTNATNYREKLMGLQALSFEIKLKDEMLALINQELKEKSSQLSEILMQVNFYKQKLQTAVESREIIINQLNQRIYE 3378
+Q K K ++ DL++ E ++E +A E +ER Y + M + IEM T+DKEMAEE+ E + Q+ LK+ +++ + +LK SDG + + + K+AL+ + + K+E+ L N EL+++++ + E+L+ ++ + E + E+K+ VD+ E +++ LT +N +E K +++RE + + +N + +E+Q + ++E E L + R+ ++ + + + +KK A +D REL+ + F + E + IE +L+ +E++ + + LL ++P SF PGG+HD + + ++ +LI K L+ +++ ++ D SE E ++ L GL L LQ +H AL Q + S + ++ E+++D LI+L+ K LD + N + ++I ++Q+ Y+ Q D +++ + I +C+ ++ + L+ G++ + L + T+ T + + R + F S VS K + ++ L ++ + + L + A+ L +I+ + +S E L S + + + + + G YDA++ + ++ A R ++ + L +++ ++ ++ + + LK K +LSE ++++ ++KL +A + + I ++ R+ E
Sbjct: 258 VQEWKSKMQEQQADLQRRLKEARKEAKEALEAKER-------YMEEMADTADAIEMATLDKEMAEERAESLQQEVEALKERVDELTTDLEILKAEIEEKGSDGAASSYQLKQLEEQNARLKDALVRMRDLSSSEKQEHVKLQKLMEKKNQELEVVRQ-------QRERLQEELSQAESTIDELKEQVDAALGAEEMVEMLTDRNLN-------------------------LEEKVRELRETVGDLEAMNEMNDELQENARETELELREQL---DMAGARVREAQKRVEAAQETVADYQQTIKKYRQLTAHLQDVNRELTNQQEASVERQQQPPPETFDFKIKFAETKAHAKAIEMELRQMEVAQANRHMSLLTAFMPDSFLRPGGDHDCVLVLLLMPRLICKAELI------RKQAQEKFDLSENCSERPGLRGAAGEQLSFAAGLVYSLSLLQATLHRYE-HALSQCSVDVYKKVGSLYPEMSAHERSLDFLIELLHKDQLDETVNVEPLTKAIKYYQHLYSIHLAEQPEDSTMQLADHIKFTQSALDCMGVEVGRLRAFLQG--GQEATDIALLLRDLETSCSDTRQFCKKIRRRMPGTDAPGIPAALAFGSQVSDTLLDCRKHLTWVVAVLQEVAAAAAQLIAPLAENEGLPVAALEELAFKASEQIYGSPS-----SSPYECLRQSCTILISTMNKLATAMQEGEYDAER-PPSKPPPVELRAAALRAEITDAEGLGLKLEDRETVIKELKKSLKIKGEELSEANVRLSLLEKKLDSAAKDADERIEKVQTRLDE 1000 HSP 2 Score: 65.4698 bits (158), Expect = 5.453e-10 Identity = 36/90 (40.00%), Postives = 50/90 (55.56%), Query Frame = 1
Query: 145 GTVRFIGSTASAKGTFYGIELHTADGRTDGTMDGISYFECKEKHGIFARRSQLTKIQ-STEVTSSE--NEVHDKLLNSCGETRDLTAQTS 405
GTV ++G+T A G + G+ L A G+ DGT+ G YF C E HGIF R+SQ+ + + TS E + K+L G D A+TS
Sbjct: 42 GTVAYVGATLFATGKWVGVILDEAKGKNDGTVQGRKYFTCDEGHGIFVRQSQIQVFEDGADTTSPETPDSSASKVLKREGA--DAAAKTS 129
BLAST of Centrosome-associated protein 350 vs. Ensembl Mouse
Match: Dctn1 (dynactin 1 [Source:MGI Symbol;Acc:MGI:107745]) HSP 1 Score: 100.138 bits (248), Expect = 1.491e-20 Identity = 161/800 (20.12%), Postives = 343/800 (42.88%), Query Frame = 1
Query: 1186 LQILKKKEYKRCGDLEKLNNELQRELLDAKEREERIKKEFDSYRDMMRSGEEEIEMITIDKEMAEEKLEQVNQDYRNLKKLYEQVLEENSMLK------NSDGTSDAKIFIDQTSTINKYKNALLELSQSINCYKEENRNL-------NSELDILKELQIFQENESEQLKSKIEKHEKDLKEMKDLVDSTADVEVILDKLTFKNXXXXXXXXXXXXXXXXXXXXXXXXXXVIESKDKKIREFHEECDCLNLIVNEIQNALDKKKIENSELLKTTNQMNERICXXXXXXXXXXXXXXXXXXXVKK-----AKAKD--RELS----------------SLTFSKQNIEKNEMKRDIENKLKTIEISHKSHQVQLLIQYLPASFSLPGGEHDLIETVQIVDKLIDKISLVLEYIIQKRRLYQQRDNSEKTPENICIQYKLEFLLLIWCGL---LKQLQINIHHSSPEALCQ--------LRSEFKQILQQEQNIDLLIDLMKKQCLDNSRNFSGVLQSIAFFQNFYADRFCYQQIDCNLKMENFISILSKGSECLRNDLSWIDQMLENNVGEQTLKLMDNLNKISTNVQSTMKNTQMYLRH---------NQRITFDSSVS-------KSIDGIIFSLMDIVLSISDFALQLTDERIFSDEAMCRLT-----EIFANNRNPLNPTSDNEILF-SLNSIDKQVENIVSNFKSGVYDADKLNKTFNSAIDTNATNYREKLMGLQALSFEIKLKDEMLALINQELKEKSSQLSEILMQVNFYKQKLQTAVESREIIINQLNQRIYE 3378
+Q K K ++ DL++ E ++E +A E +ER Y + M + IEM T+DKEMAEE+ E + Q+ LK+ +++ + +LK SDG + + + K+AL+ + + K+E+ L N EL+++++ + E+L+ ++ + E + E+K+ VD+ E +++ LT +N +E K +++RE + + +N + +E+Q + ++E E L + R+ ++ + + + +KK A +D REL+ + F + E + IE +L+ +E++ + + LL ++P SF PGG+HD + + ++ +LI K L+ +++ ++ D SE E ++ L GL L LQ +H AL Q + S + ++ E+++D LI+L+ K LD + N + ++I ++Q+ Y+ Q D +++ + I +C+ ++ + L+ G++ + L + T+ T + + R + F S VS K + ++ L ++ + + L + A+ L +I+ + +S E L S + + + + + G YDA++ + ++ A R ++ + L +++ ++ ++ + + LK K +LSE ++++ ++KL +A + + I ++ R+ E
Sbjct: 221 VQEWKSKMQEQQADLQRRLKEARKEAKEALEAKER-------YMEEMADTADAIEMATLDKEMAEERAESLQQEVEALKERVDELTTDLEILKAEIEEKGSDGAASSYQLKQLEEQNARLKDALVRMRDLSSSEKQEHVKLQKLMEKKNQELEVVRQ-------QRERLQEELSQAESTIDELKEQVDAALGAEEMVEMLTDRNLN-------------------------LEEKVRELRETVGDLEAMNEMNDELQENARETELELREQL---DMAGARVREAQKRVEAAQETVADYQQTIKKYRQLTAHLQDVNRELTNQQEASVERQQQPPPETFDFKIKFAETKAHAKAIEMELRQMEVAQANRHMSLLTAFMPDSFLRPGGDHDCVLVLLLMPRLICKAELI------RKQAQEKFDLSENCSERPGLRGAAGEQLSFAAGLVYSLSLLQATLHRYE-HALSQCSVDVYKKVGSLYPEMSAHERSLDFLIELLHKDQLDETVNVEPLTKAIKYYQHLYSIHLAEQPEDSTMQLADHIKFTQSALDCMGVEVGRLRAFLQG--GQEATDIALLLRDLETSCSDTRQFCKKIRRRMPGTDAPGIPAALAFGSQVSDTLLDCRKHLTWVVAVLQEVAAAAAQLIAPLAENEGLPVAALEELAFKASEQIYGSPS-----SSPYECLRQSCTILISTMNKLATAMQEGEYDAER-PPSKPPPVELRAAALRAEITDAEGLGLKLEDRETVIKELKKSLKIKGEELSEANVRLSLLEKKLDSAAKDADERIEKVQTRLDE 963 HSP 2 Score: 65.4698 bits (158), Expect = 5.049e-10 Identity = 37/103 (35.92%), Postives = 55/103 (53.40%), Query Frame = 1
Query: 145 GTVRFIGSTASAKGTFYGIELHTADGRTDGTMDGISYFECKEKHGIFARRSQLTKIQ-STEVTSSE--NEVHDKLLNSCGETRDLTAQTSDKIASHIKTNNIV 444
GTV ++G+T A G + G+ L A G+ DGT+ G YF C E HGIF R+SQ+ + + TS E + K+L G D A+TS K+ + + +
Sbjct: 25 GTVAYVGATLFATGKWVGVILDEAKGKNDGTVQGRKYFTCDEGHGIFVRQSQIQVFEDGADTTSPETPDSSASKVLKREGA--DAAAKTS-KLPTRPASTGVA 124
BLAST of Centrosome-associated protein 350 vs. Ensembl Mouse
Match: Dctn1 (dynactin 1 [Source:MGI Symbol;Acc:MGI:107745]) HSP 1 Score: 99.7525 bits (247), Expect = 1.797e-20 Identity = 161/800 (20.12%), Postives = 343/800 (42.88%), Query Frame = 1
Query: 1186 LQILKKKEYKRCGDLEKLNNELQRELLDAKEREERIKKEFDSYRDMMRSGEEEIEMITIDKEMAEEKLEQVNQDYRNLKKLYEQVLEENSMLK------NSDGTSDAKIFIDQTSTINKYKNALLELSQSINCYKEENRNL-------NSELDILKELQIFQENESEQLKSKIEKHEKDLKEMKDLVDSTADVEVILDKLTFKNXXXXXXXXXXXXXXXXXXXXXXXXXXVIESKDKKIREFHEECDCLNLIVNEIQNALDKKKIENSELLKTTNQMNERICXXXXXXXXXXXXXXXXXXXVKK-----AKAKD--RELS----------------SLTFSKQNIEKNEMKRDIENKLKTIEISHKSHQVQLLIQYLPASFSLPGGEHDLIETVQIVDKLIDKISLVLEYIIQKRRLYQQRDNSEKTPENICIQYKLEFLLLIWCGL---LKQLQINIHHSSPEALCQ--------LRSEFKQILQQEQNIDLLIDLMKKQCLDNSRNFSGVLQSIAFFQNFYADRFCYQQIDCNLKMENFISILSKGSECLRNDLSWIDQMLENNVGEQTLKLMDNLNKISTNVQSTMKNTQMYLRH---------NQRITFDSSVS-------KSIDGIIFSLMDIVLSISDFALQLTDERIFSDEAMCRLT-----EIFANNRNPLNPTSDNEILF-SLNSIDKQVENIVSNFKSGVYDADKLNKTFNSAIDTNATNYREKLMGLQALSFEIKLKDEMLALINQELKEKSSQLSEILMQVNFYKQKLQTAVESREIIINQLNQRIYE 3378
+Q K K ++ DL++ E ++E +A E +ER Y + M + IEM T+DKEMAEE+ E + Q+ LK+ +++ + +LK SDG + + + K+AL+ + + K+E+ L N EL+++++ + E+L+ ++ + E + E+K+ VD+ E +++ LT +N +E K +++RE + + +N + +E+Q + ++E E L + R+ ++ + + + +KK A +D REL+ + F + E + IE +L+ +E++ + + LL ++P SF PGG+HD + + ++ +LI K L+ +++ ++ D SE E ++ L GL L LQ +H AL Q + S + ++ E+++D LI+L+ K LD + N + ++I ++Q+ Y+ Q D +++ + I +C+ ++ + L+ G++ + L + T+ T + + R + F S VS K + ++ L ++ + + L + A+ L +I+ + +S E L S + + + + + G YDA++ + ++ A R ++ + L +++ ++ ++ + + LK K +LSE ++++ ++KL +A + + I ++ R+ E
Sbjct: 258 VQEWKSKMQEQQADLQRRLKEARKEAKEALEAKER-------YMEEMADTADAIEMATLDKEMAEERAESLQQEVEALKERVDELTTDLEILKAEIEEKGSDGAASSYQLKQLEEQNARLKDALVRMRDLSSSEKQEHVKLQKLMEKKNQELEVVRQ-------QRERLQEELSQAESTIDELKEQVDAALGAEEMVEMLTDRNLN-------------------------LEEKVRELRETVGDLEAMNEMNDELQENARETELELREQL---DMAGARVREAQKRVEAAQETVADYQQTIKKYRQLTAHLQDVNRELTNQQEASVERQQQPPPETFDFKIKFAETKAHAKAIEMELRQMEVAQANRHMSLLTAFMPDSFLRPGGDHDCVLVLLLMPRLICKAELI------RKQAQEKFDLSENCSERPGLRGAAGEQLSFAAGLVYSLSLLQATLHRYE-HALSQCSVDVYKKVGSLYPEMSAHERSLDFLIELLHKDQLDETVNVEPLTKAIKYYQHLYSIHLAEQPEDSTMQLADHIKFTQSALDCMGVEVGRLRAFLQG--GQEATDIALLLRDLETSCSDTRQFCKKIRRRMPGTDAPGIPAALAFGSQVSDTLLDCRKHLTWVVAVLQEVAAAAAQLIAPLAENEGLPVAALEELAFKASEQIYGSPS-----SSPYECLRQSCTILISTMNKLATAMQEGEYDAER-PPSKPPPVELRAAALRAEITDAEGLGLKLEDRETVIKELKKSLKIKGEELSEANVRLSLLEKKLDSAAKDADERIEKVQTRLDE 1000 HSP 2 Score: 65.0846 bits (157), Expect = 7.710e-10 Identity = 36/90 (40.00%), Postives = 50/90 (55.56%), Query Frame = 1
Query: 145 GTVRFIGSTASAKGTFYGIELHTADGRTDGTMDGISYFECKEKHGIFARRSQLTKIQ-STEVTSSE--NEVHDKLLNSCGETRDLTAQTS 405
GTV ++G+T A G + G+ L A G+ DGT+ G YF C E HGIF R+SQ+ + + TS E + K+L G D A+TS
Sbjct: 42 GTVAYVGATLFATGKWVGVILDEAKGKNDGTVQGRKYFTCDEGHGIFVRQSQIQVFEDGADTTSPETPDSSASKVLKREGA--DAAAKTS 129
BLAST of Centrosome-associated protein 350 vs. Ensembl Mouse
Match: Dctn1 (dynactin 1 [Source:MGI Symbol;Acc:MGI:107745]) HSP 1 Score: 98.2117 bits (243), Expect = 5.213e-20 Identity = 161/800 (20.12%), Postives = 343/800 (42.88%), Query Frame = 1
Query: 1186 LQILKKKEYKRCGDLEKLNNELQRELLDAKEREERIKKEFDSYRDMMRSGEEEIEMITIDKEMAEEKLEQVNQDYRNLKKLYEQVLEENSMLK------NSDGTSDAKIFIDQTSTINKYKNALLELSQSINCYKEENRNL-------NSELDILKELQIFQENESEQLKSKIEKHEKDLKEMKDLVDSTADVEVILDKLTFKNXXXXXXXXXXXXXXXXXXXXXXXXXXVIESKDKKIREFHEECDCLNLIVNEIQNALDKKKIENSELLKTTNQMNERICXXXXXXXXXXXXXXXXXXXVKK-----AKAKD--RELS----------------SLTFSKQNIEKNEMKRDIENKLKTIEISHKSHQVQLLIQYLPASFSLPGGEHDLIETVQIVDKLIDKISLVLEYIIQKRRLYQQRDNSEKTPENICIQYKLEFLLLIWCGL---LKQLQINIHHSSPEALCQ--------LRSEFKQILQQEQNIDLLIDLMKKQCLDNSRNFSGVLQSIAFFQNFYADRFCYQQIDCNLKMENFISILSKGSECLRNDLSWIDQMLENNVGEQTLKLMDNLNKISTNVQSTMKNTQMYLRH---------NQRITFDSSVS-------KSIDGIIFSLMDIVLSISDFALQLTDERIFSDEAMCRLT-----EIFANNRNPLNPTSDNEILF-SLNSIDKQVENIVSNFKSGVYDADKLNKTFNSAIDTNATNYREKLMGLQALSFEIKLKDEMLALINQELKEKSSQLSEILMQVNFYKQKLQTAVESREIIINQLNQRIYE 3378
+Q K K ++ DL++ E ++E +A E +ER Y + M + IEM T+DKEMAEE+ E + Q+ LK+ +++ + +LK SDG + + + K+AL+ + + K+E+ L N EL+++++ + E+L+ ++ + E + E+K+ VD+ E +++ LT +N +E K +++RE + + +N + +E+Q + ++E E L + R+ ++ + + + +KK A +D REL+ + F + E + IE +L+ +E++ + + LL ++P SF PGG+HD + + ++ +LI K L+ +++ ++ D SE E ++ L GL L LQ +H AL Q + S + ++ E+++D LI+L+ K LD + N + ++I ++Q+ Y+ Q D +++ + I +C+ ++ + L+ G++ + L + T+ T + + R + F S VS K + ++ L ++ + + L + A+ L +I+ + +S E L S + + + + + G YDA++ + ++ A R ++ + L +++ ++ ++ + + LK K +LSE ++++ ++KL +A + + I ++ R+ E
Sbjct: 124 VQEWKSKMQEQQADLQRRLKEARKEAKEALEAKER-------YMEEMADTADAIEMATLDKEMAEERAESLQQEVEALKERVDELTTDLEILKAEIEEKGSDGAASSYQLKQLEEQNARLKDALVRMRDLSSSEKQEHVKLQKLMEKKNQELEVVRQ-------QRERLQEELSQAESTIDELKEQVDAALGAEEMVEMLTDRNLN-------------------------LEEKVRELRETVGDLEAMNEMNDELQENARETELELREQL---DMAGARVREAQKRVEAAQETVADYQQTIKKYRQLTAHLQDVNRELTNQQEASVERQQQPPPETFDFKIKFAETKAHAKAIEMELRQMEVAQANRHMSLLTAFMPDSFLRPGGDHDCVLVLLLMPRLICKAELI------RKQAQEKFDLSENCSERPGLRGAAGEQLSFAAGLVYSLSLLQATLHRYE-HALSQCSVDVYKKVGSLYPEMSAHERSLDFLIELLHKDQLDETVNVEPLTKAIKYYQHLYSIHLAEQPEDSTMQLADHIKFTQSALDCMGVEVGRLRAFLQG--GQEATDIALLLRDLETSCSDTRQFCKKIRRRMPGTDAPGIPAALAFGSQVSDTLLDCRKHLTWVVAVLQEVAAAAAQLIAPLAENEGLPVAALEELAFKASEQIYGSPS-----SSPYECLRQSCTILISTMNKLATAMQEGEYDAER-PPSKPPPVELRAAALRAEITDAEGLGLKLEDRETVIKELKKSLKIKGEELSEANVRLSLLEKKLDSAAKDADERIEKVQTRLDE 866
BLAST of Centrosome-associated protein 350 vs. UniProt/SwissProt
Match: sp|Q14203|DCTN1_HUMAN (Dynactin subunit 1 OS=Homo sapiens OX=9606 GN=DCTN1 PE=1 SV=3) HSP 1 Score: 101.679 bits (252), Expect = 3.403e-20 Identity = 118/562 (21.00%), Postives = 250/562 (44.48%), Query Frame = 1
Query: 1186 LQILKKKEYKRCGDLEKLNNELQRELLDAKEREERIKKEFDSYRDMMRSGEEEIEMITIDKEMAEEKLEQVNQDYRNLKKLYEQVLEENSMLK------NSDGTSDAKIFIDQTSTINKYKNALLELSQSINCYKEENRNL-------NSELDILKELQIFQENESEQLKSKIEKHEKDLKEMKDLVDSTADVEVILDKLTFKNXXXXXXXXXXXXXXXXXXXXXXXXXXVIESKDKKIREFHEECDCLNLIVNEIQNALDKKKIENSELLKTTNQMNERICXXXXXXXXXXXXXXXXXXXVKK-----AKAKD--RELS----------------SLTFSKQNIEKNEMKRDIENKLKTIEISHKSHQVQLLIQYLPASFSLPGGEHDLIETVQIVDKLIDKISLVLEYIIQKRRLYQQRDNSEKTP-------ENICIQYKLEFLLLIWCGLLKQLQINIHHSSPEALCQLRSEFKQILQQEQNIDLLIDLMKKQCLDNSRNFSGVLQSIAFFQNFYADRFCYQQIDCNLKMENFISILSKGSECLRNDLSWIDQMLENN 2742
+Q K K ++ DL++ E ++E +A E +ER Y + M + IEM T+DKEMAEE+ E + Q+ LK+ +++ + +LK SDG + + + K+AL+ + + K+E+ L N EL+++++ + E+L+ ++ + E + E+K+ VD+ E +++ LT +N +E K +++RE + + +N + +E+Q + ++E E L + R+ ++ + + + +KK A +D REL+ + F + E + IE +L+ +E++ + + LL ++P SF PGG+HD + + ++ +LI K L+ + +K ++ +N + P E + L + L + L + + + S + ++ S + ++ E+++D LI+L+ K LD + N + ++I ++Q+ Y+ Q DC +++ + I +C+ ++ + L+
Sbjct: 258 VQEWKSKMQEQQADLQRRLKEARKEAKEALEAKER-------YMEEMADTADAIEMATLDKEMAEERAESLQQEVEALKERVDELTTDLEILKAEIEEKGSDGAASSYQLKQLEEQNARLKDALVRMRDLSSSEKQEHVKLQKLMEKKNQELEVVRQ-------QRERLQEELSQAESTIDELKEQVDAALGAEEMVEMLTDRNLN-------------------------LEEKVRELRETVGDLEAMNEMNDELQENARETELELREQL---DMAGARVREAQKRVEAAQETVADYQQTIKKYRQLTAHLQDVNRELTNQQEASVERQQQPPPETFDFKIKFAETKAHAKAIEMELRQMEVAQANRHMSLLTAFMPDSFLRPGGDHDCVLVLLLMPRLICKAELIRKQAQEK---FELSENCSERPGLRGAAGEQLSFAAGLVYSLSLLQATLHRYEHALSQCSVDVYKKVGSLYPEMSAHERSLDFLIELLHKDQLDETVNVEPLTKAIKYYQHLYSIHLAEQPEDCTMQLADHIKFTQSALDCMSVEVGRLRAFLQGG 774 HSP 2 Score: 65.855 bits (159), Expect = 2.787e-9 Identity = 37/90 (41.11%), Postives = 51/90 (56.67%), Query Frame = 1
Query: 145 GTVRFIGSTASAKGTFYGIELHTADGRTDGTMDGISYFECKEKHGIFARRSQLTKIQ-STEVTSSE--NEVHDKLLNSCGETRDLTAQTS 405
GTV ++G+T A G + G+ L A G+ DGT+ G YF C E HGIF R+SQ+ + + TS E + K+L E D TA+TS
Sbjct: 42 GTVAYVGATLFATGKWVGVILDEAKGKNDGTVQGRKYFTCDEGHGIFVRQSQIQVFEDGADTTSPETPDSSASKVLKR--EGTDTTAKTS 129
BLAST of Centrosome-associated protein 350 vs. UniProt/SwissProt
Match: sp|O08788|DCTN1_MOUSE (Dynactin subunit 1 OS=Mus musculus OX=10090 GN=Dctn1 PE=1 SV=3) HSP 1 Score: 99.7525 bits (247), Expect = 1.257e-19 Identity = 161/800 (20.12%), Postives = 343/800 (42.88%), Query Frame = 1
Query: 1186 LQILKKKEYKRCGDLEKLNNELQRELLDAKEREERIKKEFDSYRDMMRSGEEEIEMITIDKEMAEEKLEQVNQDYRNLKKLYEQVLEENSMLK------NSDGTSDAKIFIDQTSTINKYKNALLELSQSINCYKEENRNL-------NSELDILKELQIFQENESEQLKSKIEKHEKDLKEMKDLVDSTADVEVILDKLTFKNXXXXXXXXXXXXXXXXXXXXXXXXXXVIESKDKKIREFHEECDCLNLIVNEIQNALDKKKIENSELLKTTNQMNERICXXXXXXXXXXXXXXXXXXXVKK-----AKAKD--RELS----------------SLTFSKQNIEKNEMKRDIENKLKTIEISHKSHQVQLLIQYLPASFSLPGGEHDLIETVQIVDKLIDKISLVLEYIIQKRRLYQQRDNSEKTPENICIQYKLEFLLLIWCGL---LKQLQINIHHSSPEALCQ--------LRSEFKQILQQEQNIDLLIDLMKKQCLDNSRNFSGVLQSIAFFQNFYADRFCYQQIDCNLKMENFISILSKGSECLRNDLSWIDQMLENNVGEQTLKLMDNLNKISTNVQSTMKNTQMYLRH---------NQRITFDSSVS-------KSIDGIIFSLMDIVLSISDFALQLTDERIFSDEAMCRLT-----EIFANNRNPLNPTSDNEILF-SLNSIDKQVENIVSNFKSGVYDADKLNKTFNSAIDTNATNYREKLMGLQALSFEIKLKDEMLALINQELKEKSSQLSEILMQVNFYKQKLQTAVESREIIINQLNQRIYE 3378
+Q K K ++ DL++ E ++E +A E +ER Y + M + IEM T+DKEMAEE+ E + Q+ LK+ +++ + +LK SDG + + + K+AL+ + + K+E+ L N EL+++++ + E+L+ ++ + E + E+K+ VD+ E +++ LT +N +E K +++RE + + +N + +E+Q + ++E E L + R+ ++ + + + +KK A +D REL+ + F + E + IE +L+ +E++ + + LL ++P SF PGG+HD + + ++ +LI K L+ +++ ++ D SE E ++ L GL L LQ +H AL Q + S + ++ E+++D LI+L+ K LD + N + ++I ++Q+ Y+ Q D +++ + I +C+ ++ + L+ G++ + L + T+ T + + R + F S VS K + ++ L ++ + + L + A+ L +I+ + +S E L S + + + + + G YDA++ + ++ A R ++ + L +++ ++ ++ + + LK K +LSE ++++ ++KL +A + + I ++ R+ E
Sbjct: 258 VQEWKSKMQEQQADLQRRLKEARKEAKEALEAKER-------YMEEMADTADAIEMATLDKEMAEERAESLQQEVEALKERVDELTTDLEILKAEIEEKGSDGAASSYQLKQLEEQNARLKDALVRMRDLSSSEKQEHVKLQKLMEKKNQELEVVRQ-------QRERLQEELSQAESTIDELKEQVDAALGAEEMVEMLTDRNLN-------------------------LEEKVRELRETVGDLEAMNEMNDELQENARETELELREQL---DMAGARVREAQKRVEAAQETVADYQQTIKKYRQLTAHLQDVNRELTNQQEASVERQQQPPPETFDFKIKFAETKAHAKAIEMELRQMEVAQANRHMSLLTAFMPDSFLRPGGDHDCVLVLLLMPRLICKAELI------RKQAQEKFDLSENCSERPGLRGAAGEQLSFAAGLVYSLSLLQATLHRYE-HALSQCSVDVYKKVGSLYPEMSAHERSLDFLIELLHKDQLDETVNVEPLTKAIKYYQHLYSIHLAEQPEDSTMQLADHIKFTQSALDCMGVEVGRLRAFLQG--GQEATDIALLLRDLETSCSDTRQFCKKIRRRMPGTDAPGIPAALAFGSQVSDTLLDCRKHLTWVVAVLQEVAAAAAQLIAPLAENEGLPVAALEELAFKASEQIYGSPS-----SSPYECLRQSCTILISTMNKLATAMQEGEYDAER-PPSKPPPVELRAAALRAEITDAEGLGLKLEDRETVIKELKKSLKIKGEELSEANVRLSLLEKKLDSAAKDADERIEKVQTRLDE 1000 HSP 2 Score: 65.0846 bits (157), Expect = 5.393e-9 Identity = 36/90 (40.00%), Postives = 50/90 (55.56%), Query Frame = 1
Query: 145 GTVRFIGSTASAKGTFYGIELHTADGRTDGTMDGISYFECKEKHGIFARRSQLTKIQ-STEVTSSE--NEVHDKLLNSCGETRDLTAQTS 405
GTV ++G+T A G + G+ L A G+ DGT+ G YF C E HGIF R+SQ+ + + TS E + K+L G D A+TS
Sbjct: 42 GTVAYVGATLFATGKWVGVILDEAKGKNDGTVQGRKYFTCDEGHGIFVRQSQIQVFEDGADTTSPETPDSSASKVLKREGA--DAAAKTS 129
BLAST of Centrosome-associated protein 350 vs. UniProt/SwissProt
Match: sp|P28023|DCTN1_RAT (Dynactin subunit 1 OS=Rattus norvegicus OX=10116 GN=Dctn1 PE=1 SV=2) HSP 1 Score: 99.3673 bits (246), Expect = 1.824e-19 Identity = 122/566 (21.55%), Postives = 255/566 (45.05%), Query Frame = 1
Query: 1186 LQILKKKEYKRCGDLEKLNNELQRELLDAKEREERIKKEFDSYRDMMRSGEEEIEMITIDKEMAEEKLEQVNQDYRNLKKLYEQVLEENSMLK------NSDGTSDAKIFIDQTSTINKYKNALLELSQSINCYKEENRNL-------NSELDILKELQIFQENESEQLKSKIEKHEKDLKEMKDLVDSTADVEVILDKLTFKNXXXXXXXXXXXXXXXXXXXXXXXXXXVIESKDKKIREFHEECDCLNLIVNEIQNALDKKKIENSELLKTTNQMNERICXXXXXXXXXXXXXXXXXXXVKK-----AKAKD--RELS----------------SLTFSKQNIEKNEMKRDIENKLKTIEISHKSHQVQLLIQYLPASFSLPGGEHDLIETVQIVDKLIDKISLVLEYIIQKRRLYQQRDNSEKTPENICIQYKLEFLLLIWCGL---LKQLQINIHHSSPEALCQ--------LRSEFKQILQQEQNIDLLIDLMKKQCLDNSRNFSGVLQSIAFFQNFYADRFCYQQIDCNLKMENFISILSKGSECLRNDLSWIDQMLENN 2742
+Q+ + +E+K +++ +LQR L +AKE +E ++ + + Y + M + IEM T+DKEMAEE+ E + Q+ LK+ +++ + +LK SDG + + + K+AL+ + + K+E+ L N EL+++++ + E+L+ ++ + E + E+K+ VD+ E +++ LT +N +E K +++RE + + +N + +E+Q + ++E E L + R+ ++ + + + +KK A +D REL+ + F + E + IE +L+ +E++ + + LL ++P SF PGG+HD + + ++ +LI K L+ +++ ++ D SE E ++ L GL L LQ +H AL Q + S + ++ E+++D LI+L+ K LD + N + ++I ++Q+ Y+ Q + +++ + I +C+ ++ + L+
Sbjct: 253 IQLEQVQEWK--SKMQEQQADLQRRLKEAKEAKEALEAK-ERYMEEMADTADAIEMATLDKEMAEERAESLQQEVEALKERVDELTTDLEILKAEIEEKGSDGAASSYQLKQLEEQNARLKDALVRMRDLSSSEKQEHVKLQKLMEKKNQELEVVRQ-------QRERLQEELSQAESTIDELKEQVDAALGAEEMVEMLTDRNLN-------------------------LEEKVRELRETVGDLEAMNEMNDELQENARETELELREQL---DMAGARVREAQKRVEAAQETVADYQQTIKKYRQLTAHLQDVNRELTNQQEASVERQQQPPPETFDFKIKFAETKAHAKAIEMELRQMEVAQANRHMSLLTAFMPDSFLRPGGDHDCVLVLLLMPRLICKAELI------RKQAQEKFDLSENCSERPGLRGAAGEQLSFAAGLVYSLSLLQATLHRYE-HALSQCSVDVYKKVGSLYPEMSAHERSLDFLIELLHKDQLDETVNVEPLTKAIKYYQHLYSIHLAEQPEESTMQLADHIKFTQSALDCMSVEVGRLRAFLQGG 773 HSP 2 Score: 65.0846 bits (157), Expect = 4.830e-9 Identity = 36/90 (40.00%), Postives = 50/90 (55.56%), Query Frame = 1
Query: 145 GTVRFIGSTASAKGTFYGIELHTADGRTDGTMDGISYFECKEKHGIFARRSQLTKIQ-STEVTSSE--NEVHDKLLNSCGETRDLTAQTS 405
GTV ++G+T A G + G+ L A G+ DGT+ G YF C E HGIF R+SQ+ + + TS E + K+L G D A+TS
Sbjct: 42 GTVAYVGATLFATGKWVGVILDEAKGKNDGTVQGRKYFTCDEGHGIFVRQSQIQVFEDGADTTSPETPDSSASKILKREGA--DAAAKTS 129
BLAST of Centrosome-associated protein 350 vs. UniProt/SwissProt
Match: sp|Q6PCJ1|DCTN1_XENLA (Dynactin subunit 1 OS=Xenopus laevis OX=8355 GN=dctn1 PE=2 SV=1) HSP 1 Score: 90.8929 bits (224), Expect = 7.047e-17 Identity = 146/739 (19.76%), Postives = 305/739 (41.27%), Query Frame = 1
Query: 1312 YRDMMRSGEEEIEMITIDKEMAEEKLEQVNQDYRNLKKLYE------QVLEENSMLKNSDGTSDA---KIFIDQTSTINKYKNALLELSQS-----INCYKEENRNLNSELDILKELQIFQENESEQLKSKIEKHEKDLKEMKDLVDSTADVEVILDKLTFKNXXXXXXXXXXXXXXXXXXXXXXXXXXVIESKDKKIREFHEECDCLNLIVNEIQNALDKKKIENSELLKTTNQMNERICXXXXXXXXXXXXXXXXXXXVKKAK---AKDRELSSLTFSKQ--NIEKNEMK------------------RDIENKLKTIEISHKSHQVQLLIQYLPASFSLPGGEHDLIETVQIVDKLIDKISLVLEYIIQKRRLY----QQRDNSEKTPENICIQYKLEFLLLIWCGLLKQLQINIHHSSPEALCQLRSEFKQILQQEQNIDLLIDLMKKQCLDNSRNFSGVLQSIAFFQNFYADRFCYQQIDCNLKMENFISILSKGSECLRNDLSWIDQMLENNVGEQTLKLMDNLNKISTNVQSTMKNTQMYLRHNQRITFDSSVSKSIDGIIFSLMDIVLSISDFALQ-LTDERIFSDEAMCRLTEIFANNRNPLNPTSDNEILFSLNSID---KQVENI--------------------------VSNFKSGVYDADKLNKTFNSAIDTNATNYREKLMGLQALSFEIKLKDEMLALINQELKEKSSQLSEILMQVNFYKQK 3315
Y + M + IEM T+DKEMAEE+ E + Q+ LK E ++L+ K SDG + + K +Q + + + + +LS S I K+ + N+ELD L++ + E+L+ + EK + E+K+ VD+ E +++ L +N +E K +++RE + + +N + +E+Q + ++E E L + R+ ++ + + + +KK + A +E++S ++Q ++EK + + IE +L+ +E++ + V LL ++P SF GG+HD I + ++ +LI K L+ + +K L Q+ E + L + L + L + + + S E ++ + ++ E+++D LI+L+ K LD + N + ++I ++Q+ Y+ Q +C +++ + I +C+ ++S + L + G+++ L + T+ + F + + + G + + L + L D R + + E+ A + P +NE L +L D K E I + + G YDA+K ++ A R ++ + L +++ ++ ++ + + LK K +LSE ++++ ++K
Sbjct: 251 YMEEMADTADAIEMATLDKEMAEERAESLQQEVDTLKDKVEEHKIDLEILKHEIEEKGSDGAASSYQVKQLEEQNARLKEALVRMRDLSASEKQEHIKVQKQMEKK-NTELDTLRQ-------QKEKLQEEASHMEKTIDELKEQVDAALGAEEMVETLAERNLD-------------------------LEEKVRELRETVSDLEAINEMNDELQENARETELELREQL---DMAGARVREAEKRVEAAQETVADYQQTIKKYRDLTAHLQEVNSELRNQQEASVEKEQQPSPEMFDFKIKFAETKAHAKAIEMELRKMEVTQANRHVSLLTSFMPDSFLRHGGDHDCILVLLLIPRLICKAELISKQAQEKFELSEVGEQKSGMRGAVGEQMSFAAGLVYSLTLLQATLHKYEQALDKCSVEVYKKVGMLYPEMSVHERSLDFLIELLHKDQLDETVNVEPLTKAIKYYQHLYSIHLADQAEECTMQLSDHIKFTQSALDCMGVEVSRLRAFL--HAGQESSDFAILLKDLETSCSDIRQ-------------FCKKIRRRMPGTEAAGIPAALGFGQQVCETLLDCRKYLKCVVAVFQEVAAAGAQMIAPMGENEGLQALKLEDVAFKATEQIYGTKGSNPYECLRQSCSVVIATMNKMATAMQEGEYDAEKPQSKSPPPVEQRAAALRAEITDAEGLGLKLEDRETVIKELKKSLKIKGEELSEANVRLSLLEKK 938 HSP 2 Score: 65.855 bits (159), Expect = 2.600e-9 Identity = 30/79 (37.97%), Postives = 46/79 (58.23%), Query Frame = 1
Query: 103 FQIGDSV-LYNSKLEGTVRFIGSTASAKGTFYGIELHTADGRTDGTMDGISYFECKEKHGIFARRSQLTKIQSTEVTSS 336
++G V + GTV ++G+T A G + G+ L + G+ DGT+ G YF C+E HGIF R+SQ+ I+ T+S
Sbjct: 10 LKVGSRVEVIGKGYRGTVAYVGATLFATGKWVGVILDDSKGKNDGTVQGRRYFTCEENHGIFVRQSQIQVIEDGADTTS 88
BLAST of Centrosome-associated protein 350 vs. UniProt/SwissProt
Match: sp|P35458|DCTN1_CHICK (Dynactin subunit 1 OS=Gallus gallus OX=9031 GN=DCTN1 PE=1 SV=2) HSP 1 Score: 90.1225 bits (222), Expect = 1.149e-16 Identity = 122/545 (22.39%), Postives = 241/545 (44.22%), Query Frame = 1
Query: 1186 LQILKKKEYKRCGDLEKLNNELQRELLDAKEREERIKKEFDSYRDMMRSGEEEIEMITIDKEMAEEKLEQVNQDYRNLKKLYE------QVLEENSMLKNSDGTSDAKIFIDQTSTINKYKNALLELSQSINCYKEENRNL-------NSELDILKELQIFQENESEQLKSKIEKHEKDLKEMKDLVDSTADVEVILDKLTFKNXXXXXXXXXXXXXXXXXXXXXXXXXXVIESKDKKIREFHEECDCLNLIVNEIQNALDKKKIENSELLKTTNQMNERICXXXXXXXXXXXXXXXXXXXVKK-----AKAKD--RELSS---LTFSKQNIEKNEM-------------KRDIENKLKTIEISHKSHQVQLLIQYLPASFSLPGGEHDLIETVQIVDKLIDKISLVLEYIIQKRRLYQ----QRDNSEKTPENICIQYKLEFLLLIWCGLLKQLQINIHHSSPEALCQLRSEFKQILQQEQNIDLLIDLMKKQCLDNSRNFSGVLQSIAFFQNFYADRFCYQQIDCNLKMENFISILSKGSECL 2700
+Q K K ++ DL++ E ++E DA E +ER Y + M + IEM T+DKEMAEE+ E + Q+ +LK+ E ++L+ K SDG + + + K AL+ + K+E+ L N+EL+ L++ + E+L+ ++++ EK + E+K+ VD+ E +++ LT +N +E K +++RE + + +N + +E+Q + ++E E L + R+ ++ + + + +KK A +D REL S + KQ E+ + IE +L+ +E+ + V LL ++P SF GG+HD I + ++ +LI K ++ + +K L + + E + L + L + L + + ++ S E ++ + ++ E+++D LI+L+ K LD + N + ++I ++Q+ Y+ Q DC +++ + I +C+
Sbjct: 251 VQEWKSKMQEQQADLQRRLKEAKKEAKDALEAKER-------YMEEMADTADAIEMATLDKEMAEERAESLQQEVDSLKEKVEYLTMDLEILKHEIEEKGSDGAASSYQVKQLEEQNARLKEALVRMRDLSASEKQEHVKLQKQMEKKNTELESLRQ-------QREKLQEEVKQAEKTVDELKEQVDAALGAEEMVETLTERNLD-------------------------LEEKVRELRETVGDLEAMNEMNDELQENARETELELREQL---DLAAARVREAEKRVEAAQETVADYQQTIKKYRELTAHLQDVNRELMSQQEASAEKQQQPPPEIFDFKIKFAETKAHAKAIEMELRQMEVQQANRHVSLLTSFMPDSFLRHGGDHDCILVLLLIPRLICKADVISKQAQEKFELNENCTARAGLRGAAGEQLSFAAGLVYSLSLLQATLHKYEQALNKCSVEVYKKVGMLYPEMSVHERSLDFLIELLHKDQLDETVNVEPLTKAIKYYQHLYSIHLAEQAEDCTMQLADHIKFTQSALDCM 753 HSP 2 Score: 66.6254 bits (161), Expect = 1.700e-9 Identity = 26/53 (49.06%), Postives = 36/53 (67.92%), Query Frame = 1
Query: 145 GTVRFIGSTASAKGTFYGIELHTADGRTDGTMDGISYFECKEKHGIFARRSQL 303
GTV ++G+T A G + G+ L A G+ DGT+ G YF C+E HGIF R+SQ+
Sbjct: 43 GTVAYVGATLXATGKWVGVILDEAKGKNDGTVQGRKYFTCEENHGIFVRQSQI 95
BLAST of Centrosome-associated protein 350 vs. TrEMBL
Match: A0A0B7AZ82 (Dynactin domain-containing protein (Fragment) OS=Arion vulgaris OX=1028688 GN=ORF150889 PE=4 SV=1) HSP 1 Score: 125.946 bits (315), Expect = 2.589e-25 Identity = 129/528 (24.43%), Postives = 279/528 (52.84%), Query Frame = 1
Query: 1186 LQILKKKEYKRCGDLEKLNNELQRELLDAKEREERIKKEFDSYRDMMRSGEEEIEMITIDKEMAEEKLEQVNQDYRNLKKLYEQVLEENSMLKN------SDGTSDAKIFIDQTSTIN-KYKNALLELSQSINCYKEENRNLNSELDILK-ELQIFQENESEQLKSKIEKHEKDLKEMKDLVDSTADVEVILDKLTFKNXXXXXXXXXXXXXXXXXXXXXXXXXXVIESKDKKIREFHEECDCLNLIVNEIQNALDKKKIENSELLKTTNQMNERICXXXXXXXXXXXXXXXXXXXVKKAKAKDRELSSLTFSKQNIEKNEMKRDIENKLKTIEISHKSHQVQLLIQYLPASFSLPGGEHDLIETVQIVDKLIDKISLVLEYIIQKRRLYQ--QRDNSEKT--PENICIQYKLEFLLLIWCGLLKQLQINIHHSSPEALCQLRSEFKQILQQEQNIDLLIDLMKKQCLDNSRNFSGVLQSIAFFQNFYADRFCYQQIDCNLKMENFISILSKGSECLRNDLSWIDQML 2733
+Q+ + +EYK +++ + +LQR+L +K+ +++EF+ Y++ M E +EM T+DKEMAEEK E + + ++K+ E++ + +L+N SDG + A + Q N + K+AL++L +N K++ + +++ L+ EL + ++++ E+++ + +HEK+L ++K+ VD+ E ++++LT +N LE E++++ + +L+ L D E+ E+ E EE D ++ + E Q LD + SE KT N+ E + L +L+ K+ E + K + + + F + E + I+ +L+ +E+ + ++++I ++P +F GG+HD + ++ ++I+K L+ + K + +RD+ K+ E L LL + G++KQ + ++ S + ++ + ++ E+++D IDL++K LD + + + +S+ FFQ Y ++++DC M N + ++ + + +++ + +L
Sbjct: 84 IQLQQLQEYK--SKIQETHADLQRQLQASKKELSELQQEFEQYKEEMADVTETVEMATLDKEMAEEKAESLQAELDSMKEKVEELTIDLELLRNEISAKGSDGVA-ATFEMKQMEQQNERMKDALVKLRDMLNSEKQDRARSDKQVEKLEGELGLLKKDK-ERMQVLLSQHEKELIDLKEQVDAALGAEEMVEQLTERNLKLEDEMREIIEEKNDLEALNDMNEELQENAKTTEFELREELDMKSIKLLEFQRKLDGTQETFSEYDKTLNKFRELVANLQEQLRSKQQES--------ETKVETPTVELMDFKTKFAETKAYAKTIDMELRKLEVQQANAHIKMIISFMPEAFMGRGGDHDALSVSLMIPRIINKAELLASQVKDKFDITDKIERDHVLKSQKAEQCSFGNHLILLLNVLQGVMKQYESALNSCSTDLFLKIGTLVPEMTAHEKSVDYFIDLLRKDQLDETVSLDLLEKSVNFFQQLYTVHLSHERVDCTHMMTNGVRVVLTACDAISTEIARLKILL 599
BLAST of Centrosome-associated protein 350 vs. TrEMBL
Match: A0A0B7AYS5 (Dynactin domain-containing protein (Fragment) OS=Arion vulgaris OX=1028688 GN=ORF150896 PE=4 SV=1) HSP 1 Score: 125.946 bits (315), Expect = 3.023e-25 Identity = 129/528 (24.43%), Postives = 279/528 (52.84%), Query Frame = 1
Query: 1186 LQILKKKEYKRCGDLEKLNNELQRELLDAKEREERIKKEFDSYRDMMRSGEEEIEMITIDKEMAEEKLEQVNQDYRNLKKLYEQVLEENSMLKN------SDGTSDAKIFIDQTSTIN-KYKNALLELSQSINCYKEENRNLNSELDILK-ELQIFQENESEQLKSKIEKHEKDLKEMKDLVDSTADVEVILDKLTFKNXXXXXXXXXXXXXXXXXXXXXXXXXXVIESKDKKIREFHEECDCLNLIVNEIQNALDKKKIENSELLKTTNQMNERICXXXXXXXXXXXXXXXXXXXVKKAKAKDRELSSLTFSKQNIEKNEMKRDIENKLKTIEISHKSHQVQLLIQYLPASFSLPGGEHDLIETVQIVDKLIDKISLVLEYIIQKRRLYQ--QRDNSEKT--PENICIQYKLEFLLLIWCGLLKQLQINIHHSSPEALCQLRSEFKQILQQEQNIDLLIDLMKKQCLDNSRNFSGVLQSIAFFQNFYADRFCYQQIDCNLKMENFISILSKGSECLRNDLSWIDQML 2733
+Q+ + +EYK +++ + +LQR+L +K+ +++EF+ Y++ M E +EM T+DKEMAEEK E + + ++K+ E++ + +L+N SDG + A + Q N + K+AL++L +N K++ + +++ L+ EL + ++++ E+++ + +HEK+L ++K+ VD+ E ++++LT +N LE E++++ + +L+ L D E+ E+ E EE D ++ + E Q LD + SE KT N+ E + L +L+ K+ E + K + + + F + E + I+ +L+ +E+ + ++++I ++P +F GG+HD + ++ ++I+K L+ + K + +RD+ K+ E L LL + G++KQ + ++ S + ++ + ++ E+++D IDL++K LD + + + +S+ FFQ Y ++++DC M N + ++ + + +++ + +L
Sbjct: 84 IQLQQLQEYK--SKIQETHADLQRQLQASKKELSELQQEFEQYKEEMADVTETVEMATLDKEMAEEKAESLQAELDSMKEKVEELTIDLELLRNEISAKGSDGVA-ATFEMKQMEQQNERMKDALVKLRDMLNSEKQDRARSDKQVEKLEGELGLLKKDK-ERMQVLLSQHEKELIDLKEQVDAALGAEEMVEQLTERNLKLEDEMREIIEEKNDLEALNDMNEELQENAKTTEFELREELDMKSIKLLEFQRKLDGTQETFSEYDKTLNKFRELVANLQEQLRSKQQES--------ETKVETPTVELMDFKTKFAETKAYAKTIDMELRKLEVQQANAHIKMIISFMPEAFMGRGGDHDALSVSLMIPRIINKAELLASQVKDKFDITDKIERDHVLKSQKAEQCSFGNHLILLLNVLQGVMKQYESALNSCSTDLFLKIGTLVPEMTAHEKSVDYFIDLLRKDQLDETVSLDLLEKSVNFFQQLYTVHLSHERVDCTHMMTNGVRVVLTACDAISTEIARLKILL 599
BLAST of Centrosome-associated protein 350 vs. TrEMBL
Match: A0A2C9LC92 (CAP-Gly domain-containing protein OS=Biomphalaria glabrata OX=6526 GN=106072715 PE=4 SV=1) HSP 1 Score: 120.168 bits (300), Expect = 1.635e-23 Identity = 132/539 (24.49%), Postives = 279/539 (51.76%), Query Frame = 1
Query: 1186 LQILKKKEYKRCGDLEKLNNELQRELLDAKEREERIKKEFDSYRDMMRSGEEEIEMITIDKEMAEEKLEQVNQDYRNLKKLYEQVLEENSMLKN------SDGTSDAKIFIDQTSTIN-KYKNALLELSQSINCYKEENRN-------LNSELDILKELQIFQENESEQLKSKIEKHEKDLKEMKDLVDSTADVEVILDKLTFKNXXXXXXXXXXXXXXXXXXXXXXXXXXVIESKDKKIREFHEECDCLNLIVNEIQNALDKKKIENSELLKTTNQMNERICXXXXXXXXXXXXXXXXXXXVKKAKAKDRELSSLTFSKQNIEKNEMKRDIENKLKTIEISHKSHQVQLLIQYLPASFSLPGGEHDLIETVQIVDKLIDKISLVLEYIIQKRRLYQQRDNSEKTPENICIQYKLEFLLLIWC---------GLLKQLQINIHHSSPEALCQLRSEFKQILQQEQNIDLLIDLMKKQCLDNSRNFSGVLQSIAFFQNFYADRFCYQQIDCNLKMENFISILSKGSECLRNDLSWIDQML 2733
+Q+ + +EYK +++ + +LQR+L +K+ +++E++SY++ M E +EM T+DKEMAEEK E + + ++K+ E++ + +++N S+G + A + Q N + K+AL++L +N K++ + L SEL +L+ + E+L++++ +EK+L ++K+ VD+ E +++ LT +N LE E+K++ + +L+ L D E+ E+ E EE D N+ + EIQ LD + ++ +T N+ E + L +L+ K+ E + K + EL + F + E + I+ +L+ ++I + +++L+ ++P +F GG+HD I + +V ++++K L+ + K Y+ D E+ E++ +K E G++KQ + ++ S + ++ + ++ E+++D IDL++K LD + + + +SI+FFQ Y ++++DC M + + I+ + + +++ + +L
Sbjct: 283 IQLQQLQEYK--SRMQESHADLQRQLQASKKELSELQQEYESYKEEMADVTETVEMATLDKEMAEEKAESLQAELDSMKEKVEELTLDLELIRNEISSKGSEGVA-ATFELKQMEQQNERMKDALVKLRDMLNSEKQDRQRSDKMVEKLESELAVLR-------KDKERLQAQVTVYEKELIDLKEQVDAALGAEEMVETLTERNLKLEDEIKEILEEKNDLEALNDMNEELQENAKATELELREEVDMKNIKLLEIQRKLDATQETFADYDRTLNKFRELVAHLQEQLRSKQQESET------KVETPTAEL--MDFKTKFAETKAYAKTIDMELRRVDIHQANSHIKMLLSFMPDAFMGRGGDHDAICILLMVPRIMNKAELLASQVKDK---YEIADKLER--EHVLKSHKAEQFSFANHLNLLLNILYGIMKQYESALNSCSTDLFLKIGTLLPEMTAHEKSVDYFIDLLRKDQLDETVSVDLLEKSISFFQQLYTVHLSHERVDCTHMMSSDVRIVLSACDAIATEITRLKILL 798
BLAST of Centrosome-associated protein 350 vs. TrEMBL
Match: Q07DR3 (Dynactin 1a OS=Danio rerio OX=7955 GN=dctn1a PE=2 SV=1) HSP 1 Score: 115.931 bits (289), Expect = 3.637e-22 Identity = 160/738 (21.68%), Postives = 348/738 (47.15%), Query Frame = 1
Query: 1228 LEKLNNELQRELLDAKEREERIKKEFDSYRDMMRSGEEEIEMITIDKEMAEEKLEQVNQDYRNLKKLYEQVLEENSML------KNSDGTSDAKIFIDQTSTIN-KYKNALLELSQSINCYKEENRNL-------NSELDILKELQIFQENESEQLKSKIEKHEKDLKEMKDLVDSTADVEVILDKLTFKNXXXXXXXXXXXXXXXXXXXXXXXXXXVIESKDKKIREFHEECDCLNLIVNEIQNALDKKKIENSELLKTTNQMNERICXXXXXXXXXXXXXXXXXXXVKKAKAKDRELSSLTFSKQNIEKNEMKRDIENKLKTIEISHKSHQVQLLIQYLPASFSLPGGEHDLIETVQIVDKLIDKISLVLEYIIQKRRL----YQQRDNSEKTPENICIQYKLEFLLLIWCGLLKQLQINIHHSSPEALCQLRSEFKQILQQEQNIDLLIDLMKKQCLDNSRNFSGVLQSIAFFQNFYADRFCYQQIDCNLKMENFISILSKGSECLRNDLSWIDQMLE-NNVGEQTLKLMDNLN-----------KISTNVQST-MKNTQMYLRHNQRITFDSSVS-KSIDGIIFSLMDIVLSISDFALQLTDERIFS-----DEAMCRLTEIFANNRNPLNPTSDNEILF-SLNSIDKQVENIVSNFKSGVYDADKLNKTFNSAIDTNATNYREKLMGLQALSFEIKLKDEMLALINQELKEKSSQLSEILMQVNFYKQKLQTA 3327
+++ N+LQ++L +AK+ + D Y + M + IEM T+DKEMAEE+ E + Q+ +LK+ E++ + +L K SDG + + + Q N + K AL+ + + K+E+ L NSEL+ L+ ++ E+L+ +++ E + E+K+ VD+ E +++ LT +N LE+++++L++ + +L+ + + E+ E+ + E E+ D V E Q ++ + ++ +T N+ E L +E + E +++ A EL F + E + IE +L+ +E+S + QV LL ++P SF GG+HD I + ++ +LI K L+ + +K L ++ E + L + L + L + ++ + + ++ + + ++ E+++D LIDL+ K LD + + ++I ++Q+ Y+ C Q DC +++ + I +C+ +++ + L+ G + L+ +L+ KI + T LR +++++ + S K + ++ L ++ + + L ++ S D A + +++ LNP E L S +++ + + + + G YD+++ + ++T A R ++ + L +++ ++ ++ + + LK K +LSE ++++ ++KL T+
Sbjct: 214 MQEQQNDLQKQLKEAKKEAREALEAKDRYMEEMADTADAIEMATLDKEMAEERAESLQQETESLKEKLEELTMDMEILKHEIEEKGSDGAASS-YHVKQLEEQNARLKEALVRMRDLSSSEKQEHVKLQKQMEKKNSELETLR-------SQKEKLQEEMKLAEDTIDELKEQVDAALGAEEMVETLTERNLDLEEKVRELRETVSDLESINEMNDELQENARETELELREQLDLAGARVREAQKRVEAAQETLADYQQTINKYRELTTHLQEVNRELTNQQSSSAEQLQQPAA---EL--FDFKIKFAETKAYAKAIEMELRKMEVSQANRQVSLLTSFMPESFLRHGGDHDCILVLLLIPRLICKAELISKQAQEKFDLNGGSLERAGLRGAAGEQLSFASGLVYSLTLLQATLHKYELALSVCGVDVYKRMGTLYSEMCVHERSLDFLIDLLHKDQLDETVQVEPLTKAIKYYQHLYSVHLCDQPEDCTVQLADHIKFTQSALDCMGSEVGRLRAFLQAGQEGAELCVLLKDLDTSCGDIRQFCKKIRRRMPGTDAPGIPAALRFSEQVSEALADSRKQLARVVAVLQEVSAAGAQMMAPLQEQEGLSAVKIEDVAFKAVEQVYGTQG--LNP---YECLRQSCSAVIATMNKMATAMQEGEYDSERPQRP-PPPVETRAAAVRAEMTDAEGLGNKLEDRETVIKELKKSLKIKGEELSEANVRLSLLEKKLDTS 932 HSP 2 Score: 68.1662 bits (165), Expect = 1.823e-7 Identity = 30/70 (42.86%), Postives = 42/70 (60.00%), Query Frame = 1
Query: 145 GTVRFIGSTASAKGTFYGIELHTADGRTDGTMDGISYFECKEKHGIFARRSQLTKIQSTEVTSSENEVHD 354
GTV +IG+T A G + G+ L A G+ DGT+ G YF C+E HGIF R+SQ+ I +++ E D
Sbjct: 25 GTVAYIGATLFASGKWVGVILDEAKGKNDGTVQGKRYFTCEENHGIFVRQSQIQLIDDGGSSATSPETPD 94
BLAST of Centrosome-associated protein 350 vs. TrEMBL
Match: A0A286YA27 (Dynactin 1a OS=Danio rerio OX=7955 GN=dctn1a PE=1 SV=1) HSP 1 Score: 114.775 bits (286), Expect = 9.751e-22 Identity = 160/738 (21.68%), Postives = 347/738 (47.02%), Query Frame = 1
Query: 1228 LEKLNNELQRELLDAKEREERIKKEFDSYRDMMRSGEEEIEMITIDKEMAEEKLEQVNQDYRNLKKLYEQVLEENSML------KNSDGTSDAKIFIDQTSTIN-KYKNALLELSQSINCYKEENRNL-------NSELDILKELQIFQENESEQLKSKIEKHEKDLKEMKDLVDSTADVEVILDKLTFKNXXXXXXXXXXXXXXXXXXXXXXXXXXVIESKDKKIREFHEECDCLNLIVNEIQNALDKKKIENSELLKTTNQMNERICXXXXXXXXXXXXXXXXXXXVKKAKAKDRELSSLTFSKQNIEKNEMKRDIENKLKTIEISHKSHQVQLLIQYLPASFSLPGGEHDLIETVQIVDKLIDKISLVLEYIIQKRRL----YQQRDNSEKTPENICIQYKLEFLLLIWCGLLKQLQINIHHSSPEALCQLRSEFKQILQQEQNIDLLIDLMKKQCLDNSRNFSGVLQSIAFFQNFYADRFCYQQIDCNLKMENFISILSKGSECLRNDLSWIDQMLE-NNVGEQTLKLMDNLN-----------KISTNVQST-MKNTQMYLRHNQRITFDSSVS-KSIDGIIFSLMDIVLSISDFALQLTDERIFS-----DEAMCRLTEIFANNRNPLNPTSDNEILF-SLNSIDKQVENIVSNFKSGVYDADKLNKTFNSAIDTNATNYREKLMGLQALSFEIKLKDEMLALINQELKEKSSQLSEILMQVNFYKQKLQTA 3327
+++ N+LQ++L +AK+ + D Y + M + IEM T+DKEMAEE+ E + Q+ +LK+ E++ + +L K SDG + + + Q N + K AL+ + + K+E+ L NSEL+ L+ ++ E+L+ +++ E + E+K+ VD+ E +++ LT +N LE+++++L++ + +L+ + + E+ E+ + E E+ D V E Q ++ + ++ +T N+ E L +E + E +++ A EL F + E + IE +L+ +E+S + QV LL ++P SF GG+HD I + ++ +LI K L+ + +K L ++ E + L + L + L + ++ + + ++ + ++ E+++D LIDL+ K LD + + ++I ++Q+ Y+ C Q DC +++ + I +C+ +++ + L+ G + L+ +L+ KI + T LR +++++ + S K + ++ L ++ + + L ++ S D A + +++ LNP E L S +++ + + + + G YD+++ + ++T A R ++ + L +++ ++ ++ + + LK K +LSE ++++ ++KL T+
Sbjct: 246 MQEQQNDLQKQLKEAKKEAREALEAKDRYMEEMADTADAIEMATLDKEMAEERAESLQQETESLKEKLEELTMDMEILKHEIEEKGSDGAASS-YHVKQLEEQNARLKEALVRMRDLSSSEKQEHVKLQKQMEKKNSELETLR-------SQKEKLQEEMKLAEDTIDELKEQVDAALGAEEMVETLTERNLDLEEKVRELRETVSDLESINEMNDELQENARETELELREQLDLAGARVREAQKRVEAAQETLADYQQTINKYRELTTHLQEVNRELTNQQSSSAEQLQQPAA---EL--FDFKIKFAETKAYAKAIEMELRKMEVSQANRQVSLLTSFMPESFLRHGGDHDCILVLLLIPRLICKAELISKQAQEKFDLTGGSLERAGLRGAAGEQLSFASGLVYSLTLLQATLHKYELALSVCGVDVYKRMGMLYSEMCVHERSLDFLIDLLHKDQLDETVQVEPLTKAIKYYQHLYSVHLCDQPEDCTVQLADHIKFTQSALDCMGSEVGRLRAFLQAGQEGAELCVLLKDLDTSCGDIRQFCKKIRRRMPGTDAPGIPAALRFSEQVSEALADSRKQLARVVAVLQEVSAAGAQMMAPLQEQEGLSAVKIEDVAFKAVEQVYGTQG--LNP---YECLRQSCSAVIATMNKMATAMQEGEYDSERPQRP-PPPVETRAAAVRAEMTDAEGLGNKLEDRETVIKELKKSLKIKGEELSEANVRLSLLEKKLDTS 964 HSP 2 Score: 66.6254 bits (161), Expect = 4.354e-7 Identity = 29/70 (41.43%), Postives = 42/70 (60.00%), Query Frame = 1
Query: 145 GTVRFIGSTASAKGTFYGIELHTADGRTDGTMDGISYFECKEKHGIFARRSQLTKIQSTEVTSSENEVHD 354
GTV +IG+T A G + G+ L A G+ DGT+ G YF C+E HGIF R+SQ+ + +++ E D
Sbjct: 25 GTVAYIGATLFASGKWVGVILDEAKGKNDGTVQGKRYFTCEENHGIFVRQSQIQLMDDGGSSATSPETPD 94
BLAST of Centrosome-associated protein 350 vs. Ensembl Cavefish
Match: ENSAMXT00000043575.1 (dynactin subunit 1-like [Source:NCBI gene;Acc:103029055]) HSP 1 Score: 100.138 bits (248), Expect = 1.034e-20 Identity = 153/757 (20.21%), Postives = 330/757 (43.59%), Query Frame = 1
Query: 1243 NELQRELLDAKEREERIKKEFDSYRDMMRSGEEEIEMITIDKEMAEEKLEQVNQDYRNLKKLYEQVLEENSMLK------NSDGTSDAKIFIDQTSTIN-KYKNALLELSQSINCYKEENRNL-------NSELDILKELQIFQENESEQLKSKIEKHEKDLKEMKDLVDSTADVEVILDKLTFKNXXXXXXXXXXXXXXXXXXXXXXXXXXVIESKDKKIREFHEECDCLNLIVNEIQNALDKKKIENSELLKTTN----QMNERICXXXXXXXXXXXXXXXXXXXVKKAKAKDRELSS----------------LTFSKQNIEKNEMKRDIENKLKTIEISHKSHQVQLLIQYLPASFSLPGGEHDLIETVQIVDKLIDKISLVLEYIIQKRRL----YQQRDNSEKTPENICIQYKLEFLLLIWCGLLKQLQINIHHSSPEALCQLRSEFKQILQQEQNIDLLIDLMKKQCLDNSRNFSGVLQSIAFFQNFYADRFCYQQIDCNLKMENFISILSKGSECLRNDLSWIDQML---ENNVGEQTLKLM-----DNLNKISTNVQSTMKNTQM-----YLRHNQRIT-FDSSVSKSIDGIIFSLMDIVLSISDFALQLTDERIFS-----DEAMCRLTEIFANNRNPLNPTSDNEILF-SLNSIDKQVENIVSNFKSGVYDADK---LNKTFNSAIDTNATNYREKLMGLQALSFEIKLKDEMLALINQELKEKSSQLSEILMQVNFYKQKLQTAV 3330
N+LQ++L +AK+ + D Y + M + IEM T+DKEMAEE+ E + Q+ LK+ E++ + +LK +DG + + + Q N + K AL+ + K+E+ L NSEL+ L+ + E+L+ +++ E + E+K+ VD+ E +++ LT +N +E K +++RE + + +N + +E+Q + ++E E L + N+R+ + + + I K ++ + +REL++ F + E + IE +L+ +E++ + QV LL ++P SF GG+HD I + ++ +LI K L+ + +K L ++ E + L + L + L + ++ S + ++ + F ++ E+ +D LI+L+ K LD + + ++I ++Q Y+ Q DC +++ + I +C+ ++ + L + G L ++ + ++ M T L + +++ + K + ++ L ++ + + L ++ S D A + +++ ++ LNP NE L S +++ + + + + G YDA+K + T + ++ A R ++ + L +++ ++ ++ + + LK K +LSE ++++ ++KL T+
Sbjct: 87 NDLQKQLKEAKKEAREALEAKDRYMEEMADTSDAIEMATLDKEMAEERAESLQQEVEGLKEKVEELTMDLEILKHEIEEKGTDGAASS-YHVKQLEEQNGRLKEALVRMRDLSASEKQEHVKLQKQMEKKNSELETLR-------AQKEKLQEEMKHAEATIDELKEQVDAALGAEEMVETLTGRNLD-------------------------LEEKVRELRETVSDLEAINEMNDELQENARETELELREQLDLAGARVREANKRVEAAQETVADYQQTINKYRDLTAHLQELNRELTNQQSATVEQLQQPPAELFDFKIKFAETKAYAKAIEMELRKMEVAQANRQVSLLTSFMPDSFLRHGGDHDCILVLLLIPRLICKAELISKQAQEKFDLNGNVVERTGLRGSAGEQLSFASGLVYSLTLLQATLHKYDQALNQCSVDVYKRMGTLFSEMSVHERCLDFLIELLHKDQLDETVQVEPLTKAIKYYQQLYSIHLAEQTEDCTVQLADHIKFTQSALDCMGAEVGRLRSFLQAGQEGAGLTLLLKDLDTSCGDIRQFCKKIRRRMPGTDAPGIPSALSYPPQVSELLADCRKQLARVVAVLQEMGAAGAQMIAPLAEQEGLSALKLEDVAFTAVEQVYGSHG--LNP---NECLRQSCSAVIATMNKMATAMQEGEYDAEKPQLIMHTHSPPVEARAAALRAEITDAEGLGLKLEDRETVIKELKKSLKIKGEELSEANVRLSLLEKKLDTST 805
BLAST of Centrosome-associated protein 350 vs. Ensembl Cavefish
Match: ENSAMXT00000057148.1 (dynactin subunit 1-like [Source:NCBI gene;Acc:103029055]) HSP 1 Score: 98.2117 bits (243), Expect = 4.372e-20 Identity = 152/753 (20.19%), Postives = 329/753 (43.69%), Query Frame = 1
Query: 1243 NELQRELLDAKEREERIKKEFDSYRDMMRSGEEEIEMITIDKEMAEEKLEQVNQDYRNLKKLYEQVLEENSMLK------NSDGTSDAKIFIDQTSTIN-KYKNALLELSQSINCYKEENRNL-------NSELDILKELQIFQENESEQLKSKIEKHEKDLKEMKDLVDSTADVEVILDKLTFKNXXXXXXXXXXXXXXXXXXXXXXXXXXVIESKDKKIREFHEECDCLNLIVNEIQNALDKKKIENSELLKTTN----QMNERICXXXXXXXXXXXXXXXXXXXVKKAKAKDRELSS----------------LTFSKQNIEKNEMKRDIENKLKTIEISHKSHQVQLLIQYLPASFSLPGGEHDLIETVQIVDKLIDKISLVLEYIIQKRRL----YQQRDNSEKTPENICIQYKLEFLLLIWCGLLKQLQINIHHSSPEALCQLRSEFKQILQQEQNIDLLIDLMKKQCLDNSRNFSGVLQSIAFFQNFYADRFCYQQIDCNLKMENFISILSKGSECLRNDLSWIDQML---ENNVGEQTLKLM-----DNLNKISTNVQSTMKNTQM-----YLRHNQRIT-FDSSVSKSIDGIIFSLMDIVLSISDFALQLTDERIFS-----DEAMCRLTEIFANNRNPLNPTSDNEILF-SLNSIDKQVENIVSNFKSGVYDADKLNKTFNSAIDTNATNYREKLMGLQALSFEIKLKDEMLALINQELKEKSSQLSEILMQVNFYKQKLQTA 3327
N+LQ++L +AK+ + D Y + M + IEM T+DKEMAEE+ E + Q+ LK+ E++ + +LK +DG + + + Q N + K AL+ + K+E+ L NSEL+ L+ + E+L+ +++ E + E+K+ VD+ E +++ LT +N +E K +++RE + + +N + +E+Q + ++E E L + N+R+ + + + I K ++ + +REL++ F + E + IE +L+ +E++ + QV LL ++P SF GG+HD I + ++ +LI K L+ + +K L ++ E + L + L + L + ++ S + ++ + F ++ E+ +D LI+L+ K LD + + ++I ++Q Y+ Q DC +++ + I +C+ ++ + L + G L ++ + ++ M T L + +++ + K + ++ L ++ + + L ++ S D A + +++ ++ LNP NE L S +++ + + + + G YDA+K + + ++ A R ++ + L +++ ++ ++ + + LK K +LSE ++++ ++KL T+
Sbjct: 204 NDLQKQLKEAKKEAREALEAKDRYMEEMADTSDAIEMATLDKEMAEERAESLQQEVEGLKEKVEELTMDLEILKHEIEEKGTDGAASS-YHVKQLEEQNGRLKEALVRMRDLSASEKQEHVKLQKQMEKKNSELETLR-------AQKEKLQEEMKHAEATIDELKEQVDAALGAEEMVETLTGRNLD-------------------------LEEKVRELRETVSDLEAINEMNDELQENARETELELREQLDLAGARVREANKRVEAAQETVADYQQTINKYRDLTAHLQELNRELTNQQSATVEQLQQPPAELFDFKIKFAETKAYAKAIEMELRKMEVAQANRQVSLLTSFMPDSFLRHGGDHDCILVLLLIPRLICKAELISKQAQEKFDLNGNVVERTGLRGSAGEQLSFASGLVYSLTLLQATLHKYDQALNQCSVDVYKRMGTLFSEMSVHERCLDFLIELLHKDQLDETVQVEPLTKAIKYYQQLYSIHLAEQTEDCTVQLADHIKFTQSALDCMGAEVGRLRSFLQAGQEGAGLTLLLKDLDTSCGDIRQFCKKIRRRMPGTDAPGIPSALSYPPQVSELLADCRKQLARVVAVLQEMGAAGAQMIAPLAEQEGLSALKLEDVAFTAVEQVYGSHG--LNP---NECLRQSCSAVIATMNKMATAMQEGEYDAEKPQRV-SPPVEARAAALRAEITDAEGLGLKLEDRETVIKELKKSLKIKGEELSEANVRLSLLEKKLDTS 917
BLAST of Centrosome-associated protein 350 vs. Ensembl Cavefish
Match: ENSAMXT00000040825.1 (dynactin subunit 1-like [Source:NCBI gene;Acc:103029055]) HSP 1 Score: 97.8265 bits (242), Expect = 5.047e-20 Identity = 152/753 (20.19%), Postives = 329/753 (43.69%), Query Frame = 1
Query: 1243 NELQRELLDAKEREERIKKEFDSYRDMMRSGEEEIEMITIDKEMAEEKLEQVNQDYRNLKKLYEQVLEENSMLK------NSDGTSDAKIFIDQTSTIN-KYKNALLELSQSINCYKEENRNL-------NSELDILKELQIFQENESEQLKSKIEKHEKDLKEMKDLVDSTADVEVILDKLTFKNXXXXXXXXXXXXXXXXXXXXXXXXXXVIESKDKKIREFHEECDCLNLIVNEIQNALDKKKIENSELLKTTN----QMNERICXXXXXXXXXXXXXXXXXXXVKKAKAKDRELSS----------------LTFSKQNIEKNEMKRDIENKLKTIEISHKSHQVQLLIQYLPASFSLPGGEHDLIETVQIVDKLIDKISLVLEYIIQKRRL----YQQRDNSEKTPENICIQYKLEFLLLIWCGLLKQLQINIHHSSPEALCQLRSEFKQILQQEQNIDLLIDLMKKQCLDNSRNFSGVLQSIAFFQNFYADRFCYQQIDCNLKMENFISILSKGSECLRNDLSWIDQML---ENNVGEQTLKLM-----DNLNKISTNVQSTMKNTQM-----YLRHNQRIT-FDSSVSKSIDGIIFSLMDIVLSISDFALQLTDERIFS-----DEAMCRLTEIFANNRNPLNPTSDNEILF-SLNSIDKQVENIVSNFKSGVYDADKLNKTFNSAIDTNATNYREKLMGLQALSFEIKLKDEMLALINQELKEKSSQLSEILMQVNFYKQKLQTA 3327
N+LQ++L +AK+ + D Y + M + IEM T+DKEMAEE+ E + Q+ LK+ E++ + +LK +DG + + + Q N + K AL+ + K+E+ L NSEL+ L+ + E+L+ +++ E + E+K+ VD+ E +++ LT +N +E K +++RE + + +N + +E+Q + ++E E L + N+R+ + + + I K ++ + +REL++ F + E + IE +L+ +E++ + QV LL ++P SF GG+HD I + ++ +LI K L+ + +K L ++ E + L + L + L + ++ S + ++ + F ++ E+ +D LI+L+ K LD + + ++I ++Q Y+ Q DC +++ + I +C+ ++ + L + G L ++ + ++ M T L + +++ + K + ++ L ++ + + L ++ S D A + +++ ++ LNP NE L S +++ + + + + G YDA+K + + ++ A R ++ + L +++ ++ ++ + + LK K +LSE ++++ ++KL T+
Sbjct: 222 NDLQKQLKEAKKEAREALEAKDRYMEEMADTSDAIEMATLDKEMAEERAESLQQEVEGLKEKVEELTMDLEILKHEIEEKGTDGAASS-YHVKQLEEQNGRLKEALVRMRDLSASEKQEHVKLQKQMEKKNSELETLR-------AQKEKLQEEMKHAEATIDELKEQVDAALGAEEMVETLTGRNLD-------------------------LEEKVRELRETVSDLEAINEMNDELQENARETELELREQLDLAGARVREANKRVEAAQETVADYQQTINKYRDLTAHLQELNRELTNQQSATVEQLQQPPAELFDFKIKFAETKAYAKAIEMELRKMEVAQANRQVSLLTSFMPDSFLRHGGDHDCILVLLLIPRLICKAELISKQAQEKFDLNGNVVERTGLRGSAGEQLSFASGLVYSLTLLQATLHKYDQALNQCSVDVYKRMGTLFSEMSVHERCLDFLIELLHKDQLDETVQVEPLTKAIKYYQQLYSIHLAEQTEDCTVQLADHIKFTQSALDCMGAEVGRLRSFLQAGQEGAGLTLLLKDLDTSCGDIRQFCKKIRRRMPGTDAPGIPSALSYPPQVSELLADCRKQLARVVAVLQEMGAAGAQMIAPLAEQEGLSALKLEDVAFTAVEQVYGSHG--LNP---NECLRQSCSAVIATMNKMATAMQEGEYDAEKPQRV-SPPVEARAAALRAEITDAEGLGLKLEDRETVIKELKKSLKIKGEELSEANVRLSLLEKKLDTS 935
BLAST of Centrosome-associated protein 350 vs. Ensembl Cavefish
Match: dctn1b (dynactin subunit 1 [Source:NCBI gene;Acc:103040401]) HSP 1 Score: 95.9005 bits (237), Expect = 2.302e-19 Identity = 163/766 (21.28%), Postives = 329/766 (42.95%), Query Frame = 1
Query: 1243 NELQRELLDAKEREERIKKEFDSYRDMMRSGEEEIEMITIDKEMAEEKLEQVNQDYRNLKKLYEQVLEENSMLK------NSDGTSDAKIFIDQTSTIN-KYKNALLELSQSINCYKEENRNL-------NSELDILKELQIFQENESEQLKSKIEKHEKDLKEMKDLVDSTADVEVILDKLTFKNXXXXXXXXXXXXXXXXXXXXXXXXXXVIESKDKKIREFHEECDCLNLIVNEIQNALDKKKIENSELL----KTTNQMNERICXXXXXXXXXXXXXXXXXXXVKKAKAKDRELSS---------------LTFSKQNIEKNEMKRDIENKLKTIEISHKSHQVQLLIQYLPASFSLPGGEHDLIETVQIVDKLIDKISLVLEYIIQKRRLYQ---QRDNSE-KTPENICIQYKLEFLLLIWCGLLKQLQINIHHSSPEALCQLRSEFKQILQQEQNIDLLIDLMKKQCLDNSRNFSGVLQSIAFFQNFYADRFCYQQIDCNLKMENFISILSKGSECLRNDLSWIDQMLENNVGEQTLK-LMDNLNKISTNVQSTMKNTQMYLRHNQRITFDSSVSKSIDGIIFSLMDIVLSISDFALQLTDERIFSDEAMCR----LTEIFANNRNPLNPTSDNEILFSLNSID---KQVENI--------------------------VSNFKSGVYDADKLNKTFNSAIDTNATNYREKLMGLQALSFEIKLKDEMLALINQELKEKSSQLSEILMQVNFYKQKLQTA 3327
NELQ++L +AK+ + + + Y + M + IEM T+DKEMAEE+ E + + LK+ +++ + +LK SDG + + + Q N + K AL+ + K+E+ L N ELD+L+ + +E E++K EK + E+K+ VD+ E +++ LT +N +E K +++RE + + +N + +E+Q + ++E E L + + +R+ + + + IQK E+ + +REL S F + E + IE +L+ +E++ + QV LL ++P SF GG+HD I + ++ +LI K L+ + +K L + QR T E + L + L + L + + ++ S + ++ S + ++ E+++D LIDL+ K LD + N + ++I ++Q+ Y+ Q DC +++ + I +C+ ++ + L+ E L L+ +L+ ++++ K + + GI +L +F Q+ + S + L E+ A + P ++E L +L D K E I + + G YD++K + + ++ A+ R ++ + L +++ ++ ++ + + LK K +LSE ++++ ++KL +A
Sbjct: 244 NELQKQLKEAKKEAKEALEAKERYMEEMADTADAIEMATLDKEMAEERAESLQLEADALKEKVDELTMDLELLKHEIEEKGSDGAASS-YHVKQLEEQNARLKEALVRMRDLSASEKQEHLKLQKQMEKKNFELDVLR---VQKEKGQEEMKLA----EKTIDELKEQVDAALGAEQMVETLTERNLD-------------------------LEEKVRELRETVTDLEAINEMNDELQENARETELELREQLDLSAASVREAEKRVEAAQETVADYQHTIQKYRELTAHLQEANRELMSQQEATAEPQEQPAEMFDFKIKFAETKAYAKAIEMELRKMEVAQSNRQVALLTSFMPESFLRHGGDHDGILVLLLIPRLICKAELISKQAQEKFDLTENCSQRPGMRGSTGEQLSFSAGLIYSLSLLQATLHKYEHALNQCSVDVYKRVGSLYSEMSVHERSLDFLIDLLHKDQLDETVNVEPLTKAIKYYQHLYSIHLAEQSEDCTMQLADHIKFTQSALDCMAVEVGRLRAFLQAGQDETQLSVLLKDLDTSCSDIRQFCKKIRRRMPGT-----------DAPGIPAAL--------NFGPQVCETLAESRRQLAWVNAVLQEVAAAGAQLIAPLGEHEGLPTLKLEDMAFKAAEQIYGSQGINPYECLRQSCSVVIATMNKMATAMQEGEYDSEK-PQCGIAPVNVRASALRAEITDAEGLGLKLEDRETVIKELKKSLKIKGEELSEANVRLSLLEKKLDSA 956 HSP 2 Score: 64.6994 bits (156), Expect = 6.823e-10 Identity = 28/66 (42.42%), Postives = 40/66 (60.61%), Query Frame = 1
Query: 145 GTVRFIGSTASAKGTFYGIELHTADGRTDGTMDGISYFECKEKHGIFARRSQLTKIQSTEVTSSEN 342
GTV +IG+T A G + G+ L G+ DGT+ G YF C E HGIF R+SQ+ ++ T+S +
Sbjct: 44 GTVAYIGTTLFASGKWVGVILEEPKGKNDGTVQGKRYFTCLENHGIFVRQSQIQLVEDGADTTSPD 109
BLAST of Centrosome-associated protein 350 vs. Ensembl Cavefish
Match: dctn1b (dynactin subunit 1 [Source:NCBI gene;Acc:103040401]) HSP 1 Score: 95.1301 bits (235), Expect = 3.421e-19 Identity = 163/766 (21.28%), Postives = 329/766 (42.95%), Query Frame = 1
Query: 1243 NELQRELLDAKEREERIKKEFDSYRDMMRSGEEEIEMITIDKEMAEEKLEQVNQDYRNLKKLYEQVLEENSMLK------NSDGTSDAKIFIDQTSTIN-KYKNALLELSQSINCYKEENRNL-------NSELDILKELQIFQENESEQLKSKIEKHEKDLKEMKDLVDSTADVEVILDKLTFKNXXXXXXXXXXXXXXXXXXXXXXXXXXVIESKDKKIREFHEECDCLNLIVNEIQNALDKKKIENSELL----KTTNQMNERICXXXXXXXXXXXXXXXXXXXVKKAKAKDRELSS---------------LTFSKQNIEKNEMKRDIENKLKTIEISHKSHQVQLLIQYLPASFSLPGGEHDLIETVQIVDKLIDKISLVLEYIIQKRRLYQ---QRDNSE-KTPENICIQYKLEFLLLIWCGLLKQLQINIHHSSPEALCQLRSEFKQILQQEQNIDLLIDLMKKQCLDNSRNFSGVLQSIAFFQNFYADRFCYQQIDCNLKMENFISILSKGSECLRNDLSWIDQMLENNVGEQTLK-LMDNLNKISTNVQSTMKNTQMYLRHNQRITFDSSVSKSIDGIIFSLMDIVLSISDFALQLTDERIFSDEAMCR----LTEIFANNRNPLNPTSDNEILFSLNSID---KQVENI--------------------------VSNFKSGVYDADKLNKTFNSAIDTNATNYREKLMGLQALSFEIKLKDEMLALINQELKEKSSQLSEILMQVNFYKQKLQTA 3327
NELQ++L +AK+ + + + Y + M + IEM T+DKEMAEE+ E + + LK+ +++ + +LK SDG + + + Q N + K AL+ + K+E+ L N ELD+L+ + +E E++K EK + E+K+ VD+ E +++ LT +N +E K +++RE + + +N + +E+Q + ++E E L + + +R+ + + + IQK E+ + +REL S F + E + IE +L+ +E++ + QV LL ++P SF GG+HD I + ++ +LI K L+ + +K L + QR T E + L + L + L + + ++ S + ++ S + ++ E+++D LIDL+ K LD + N + ++I ++Q+ Y+ Q DC +++ + I +C+ ++ + L+ E L L+ +L+ ++++ K + + GI +L +F Q+ + S + L E+ A + P ++E L +L D K E I + + G YD++K + + ++ A+ R ++ + L +++ ++ ++ + + LK K +LSE ++++ ++KL +A
Sbjct: 225 NELQKQLKEAKKEAKEALEAKERYMEEMADTADAIEMATLDKEMAEERAESLQLEADALKEKVDELTMDLELLKHEIEEKGSDGAASS-YHVKQLEEQNARLKEALVRMRDLSASEKQEHLKLQKQMEKKNFELDVLR---VQKEKGQEEMKLA----EKTIDELKEQVDAALGAEQMVETLTERNLD-------------------------LEEKVRELRETVTDLEAINEMNDELQENARETELELREQLDLSAASVREAEKRVEAAQETVADYQHTIQKYRELTAHLQEANRELMSQQEATAEPQEQPAEMFDFKIKFAETKAYAKAIEMELRKMEVAQSNRQVALLTSFMPESFLRHGGDHDGILVLLLIPRLICKAELISKQAQEKFDLTENCSQRPGMRGSTGEQLSFSAGLIYSLSLLQATLHKYEHALNQCSVDVYKRVGSLYSEMSVHERSLDFLIDLLHKDQLDETVNVEPLTKAIKYYQHLYSIHLAEQSEDCTMQLADHIKFTQSALDCMAVEVGRLRAFLQAGQDETQLSVLLKDLDTSCSDIRQFCKKIRRRMPGT-----------DAPGIPAAL--------NFGPQVCETLAESRRQLAWVNAVLQEVAAAGAQLIAPLGEHEGLPTLKLEDMAFKAAEQIYGSQGINPYECLRQSCSVVIATMNKMATAMQEGEYDSEK-PQCGIAPVNVRASALRAEITDAEGLGLKLEDRETVIKELKKSLKIKGEELSEANVRLSLLEKKLDSA 937 HSP 2 Score: 64.6994 bits (156), Expect = 7.961e-10 Identity = 28/66 (42.42%), Postives = 40/66 (60.61%), Query Frame = 1
Query: 145 GTVRFIGSTASAKGTFYGIELHTADGRTDGTMDGISYFECKEKHGIFARRSQLTKIQSTEVTSSEN 342
GTV +IG+T A G + G+ L G+ DGT+ G YF C E HGIF R+SQ+ ++ T+S +
Sbjct: 25 GTVAYIGTTLFASGKWVGVILEEPKGKNDGTVQGKRYFTCLENHGIFVRQSQIQLVEDGADTTSPD 90
BLAST of Centrosome-associated protein 350 vs. Ensembl Sea Lamprey
Match: si:dkeyp-47f9.4 (si:dkeyp-47f9.4 [Source:ZFIN;Acc:ZDB-GENE-131126-9]) HSP 1 Score: 73.1738 bits (178), Expect = 2.394e-13 Identity = 29/71 (40.85%), Postives = 47/71 (66.20%), Query Frame = 1
Query: 100 EFQIGDSVLYNSKLEGTVRFIGSTASAKGTFYGIELHTADGRTDGTMDGISYFECKEKHGIFARRSQLTKI 312
E ++G+ +L + + G +RF G+T A G +YGIEL GR DG++ G+ YF+C KHG+FA S++ ++
Sbjct: 436 ELELGERLLVSGQRAGVLRFQGTTHFAPGHWYGIELEQPSGRNDGSVAGVRYFQCPAKHGVFAPPSRVQRL 506 HSP 2 Score: 63.5438 bits (153), Expect = 2.323e-10 Identity = 28/78 (35.90%), Postives = 44/78 (56.41%), Query Frame = 1
Query: 109 IGDSVLYNSKLEGTVRFIGSTASAKGTFYGIELHTADGRTDGTMDGISYFECKEKHGIFARRSQLTKIQSTEVTSSEN 342
+G V+ + G +RF G T A + G+EL ADG+ +G++DG YF C +HGIFA S++ + + + S N
Sbjct: 236 VGQRVIVGGRKTGVLRFCGPTEFAGDQWAGVELDEADGKNNGSVDGTRYFTCAPRHGIFAPLSKVARAEESSRHGSLN 313 HSP 3 Score: 55.4546 bits (132), Expect = 8.612e-8 Identity = 25/66 (37.88%), Postives = 36/66 (54.55%), Query Frame = 1
Query: 112 GDSVLYNSKLE-GTVRFIGSTASAKGTFYGIELHTADGRTDGTMDGISYFECKEKHGIFARRSQLT 306
G+ VL E GTVRF+G A GT+ G+EL G+ DG + G YF C+ G+ R +++
Sbjct: 578 GNQVLVAGTGEMGTVRFVGEVGFAAGTWLGLELRAPRGKHDGAVGGHRYFSCRPGCGVMVRPGRVS 643
BLAST of Centrosome-associated protein 350 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000006027.1 (pep scaffold:Pmarinus_7.0:GL478150:21952:49796:1 gene:ENSPMAG00000005440.1 transcript:ENSPMAT00000006027.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 73.1738 bits (178), Expect = 3.298e-13 Identity = 30/71 (42.25%), Postives = 45/71 (63.38%), Query Frame = 1
Query: 100 EFQIGDSVLYNSKLEGTVRFIGSTASAKGTFYGIELHTADGRTDGTMDGISYFECKEKHGIFARRSQLTKI 312
E +IGD VL + G VRF+G AKG + G+EL G+ DG++ G YF+C+ K+G+FA ++T+I
Sbjct: 235 ELKIGDRVLVSGTKAGVVRFLGEADFAKGEWCGVELDEPLGKNDGSVAGTRYFQCQPKYGLFAPTHKVTRI 305
BLAST of Centrosome-associated protein 350 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000006020.1 (pep scaffold:Pmarinus_7.0:GL478150:21952:49796:1 gene:ENSPMAG00000005440.1 transcript:ENSPMAT00000006020.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 72.4034 bits (176), Expect = 5.451e-13 Identity = 30/71 (42.25%), Postives = 45/71 (63.38%), Query Frame = 1
Query: 100 EFQIGDSVLYNSKLEGTVRFIGSTASAKGTFYGIELHTADGRTDGTMDGISYFECKEKHGIFARRSQLTKI 312
E +IGD VL + G VRF+G AKG + G+EL G+ DG++ G YF+C+ K+G+FA ++T+I
Sbjct: 231 ELKIGDRVLVSGTKAGVVRFLGEADFAKGEWCGVELDEPLGKNDGSVAGTRYFQCQPKYGLFAPTHKVTRI 301 HSP 2 Score: 55.0694 bits (131), Expect = 1.355e-7 Identity = 24/59 (40.68%), Postives = 36/59 (61.02%), Query Frame = 1
Query: 136 KLEGTVRFIGS--TASAKGTFYGIELHTADGRTDGTMDGISYFECKEKHGIFARRSQLT 306
+L+G V F G T+ A + GIEL G+ DG++ G+ YF+C+ HG+F R S+L
Sbjct: 65 RLDGPVFFWGYGLTSHAVNEWAGIELEEPVGKNDGSVAGVRYFQCRPLHGVFTRPSKLA 123
BLAST of Centrosome-associated protein 350 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000004647.1 (pep scaffold:Pmarinus_7.0:GL484285:5077:12891:1 gene:ENSPMAG00000004232.1 transcript:ENSPMAT00000004647.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 66.2402 bits (160), Expect = 2.115e-11 Identity = 28/71 (39.44%), Postives = 44/71 (61.97%), Query Frame = 1
Query: 100 EFQIGDSVLYNSKLEGTVRFIGSTASAKGTFYGIELHTADGRTDGTMDGISYFECKEKHGIFARRSQLTKI 312
+ ++GD VL G VRF+G T AKG + G+EL G+ DG + G YF+C++++G+FA ++ KI
Sbjct: 190 DLKMGDRVLVGGTKAGVVRFVGETDFAKGEWCGVELDEPLGKNDGAVAGTRYFQCQQRYGLFAPIHKVAKI 260 HSP 2 Score: 64.3142 bits (155), Expect = 9.923e-11 Identity = 28/74 (37.84%), Postives = 44/74 (59.46%), Query Frame = 1
Query: 88 QMINEFQIGDSVLYNSKLEGTVRFIGSTASAKGTFYGIELHTADGRTDGTMDGISYFECKEKHGIFARRSQLTK 309
+ I++F IG+ V N G ++++G T A G + GI L A G+ DG + G+ YF C+ GIF R S+L++
Sbjct: 23 EFIDDFIIGERVWVNGSKPGHIQYLGETQFAPGQWAGIVLDEATGKNDGAVSGVRYFMCEAGRGIFTRPSKLSR 96
BLAST of Centrosome-associated protein 350 vs. Ensembl Sea Lamprey
Match: dctn1a (dynactin 1a [Source:ZFIN;Acc:ZDB-GENE-070117-2205]) HSP 1 Score: 66.2402 bits (160), Expect = 5.233e-11 Identity = 28/67 (41.79%), Postives = 43/67 (64.18%), Query Frame = 1
Query: 145 GTVRFIGSTASAKGTFYGIELHTADGRTDGTMDGISYFECKEKHGIFARRSQLTKIQ-STEVTSSEN 342
GTV ++G+T A G + G+ L A G+ DGT+ G YF C++ HGIF R+SQ+ ++ + TS E+
Sbjct: 40 GTVAYVGATMFATGKWVGVILDEAKGKNDGTVQGKRYFTCEDNHGIFVRQSQIQLVEDGGDTTSPES 106 HSP 2 Score: 56.9954 bits (136), Expect = 3.284e-8 Identity = 54/185 (29.19%), Postives = 99/185 (53.51%), Query Frame = 1
Query: 1246 ELQRELLDAKEREERIKKEFDSYRDMMRSGEEEIEMITIDKEMAEEKLEQVNQDYRNLKKLYEQVLEENSML------KNSDGTSDAKIFIDQTSTIN-KYKNALLELSQSINCYKEE----NRNL---NSELDILKELQIFQENESEQLKSKIEKHEKDLKEMKDLVDSTADVEVILDKLTFKN 1758
+LQ++L +AK + + + + Y + M + IEM T+DKEMAEEK E + Q+ NLK+ E++ + +L K SDG + + + Q N + K AL+ + K+E +++ NSELD L+ + E+L++++++ E + E+K+ VD+ E +++ LT +N
Sbjct: 276 DLQKQLKEAKREAKEVIEAKERYMEEMADVSDAIEMATLDKEMAEEKSESLQQEVENLKEKVEELSMDLEILKHEIEEKGSDGAASS-YHVKQLEEQNARLKEALVRMRDLSTSEKQEYLKQQKHMEKKNSELDTLR-------TQKEKLQAELQQAEGIIDELKEQVDAALGAEDMVETLTERN 452
BLAST of Centrosome-associated protein 350 vs. Ensembl Yeast
Match: NIP100 (Large subunit of the dynactin complex; dynactin is involved in partitioning the mitotic spindle between mother and daughter cells; putative ortholog of mammalian p150(glued) [Source:SGD;Acc:S000006095]) HSP 1 Score: 60.8474 bits (146), Expect = 1.386e-9 Identity = 31/85 (36.47%), Postives = 50/85 (58.82%), Query Frame = 1
Query: 82 GLQM---INEFQIGDSVLYNSKLEGTVRFIGSTASAKGTFYGIELHTADGRTDGTMDGISYFECKEK--------HGIFARRSQL 303
G+Q+ + + + D+VL N +++G V+FIG T AKG +YGIEL G+ DG+ +GI YF+ K +G+F ++ L
Sbjct: 5 GVQVDTNMQKISLQDTVLVN-EMKGRVKFIGETQFAKGIWYGIELDKPLGKNDGSANGIRYFDIDLKKANSNGGYYGLFCKKDTL 88
BLAST of Centrosome-associated protein 350 vs. Ensembl Nematostella
Match: EDO33600 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SRR5]) HSP 1 Score: 75.0998 bits (183), Expect = 3.618e-14 Identity = 40/101 (39.60%), Postives = 60/101 (59.41%), Query Frame = 1
Query: 88 QMINEFQIGDSVLYNSKLEGTVRFIGSTASAKGTFYGIELHTADGRTDGTMDGISYFECKEKHGIFARRSQLTKI-QSTEVTSS--EN----EVHDKLLNS 369
+++ FQ+GD VL N+ G + F+G T AKG + GI L G+ DG++ G YFECK HG+F + ++TK+ Q TE S EN E+ D+++ S
Sbjct: 2 ELLKLFQVGDRVLVNNTKPGVIAFLGETKFAKGDWAGIILDDPTGKNDGSVAGEKYFECKPLHGVFTKLEKITKVNQVTESPGSPVENSSSLEIGDRVVVS 102 HSP 2 Score: 63.5438 bits (153), Expect = 1.861e-10 Identity = 28/76 (36.84%), Postives = 45/76 (59.21%), Query Frame = 1
Query: 103 FQIGDSVLYNSKLEGTVRFIGSTASAKGTFYGIELHTADGRTDGTMDGISYFECKEKHGIFARRSQLTKIQSTEVT 330
+IGD V+ + GT+R++G+T AKG + G+EL G+ DG + G YF+C + +G+FA ++ K E T
Sbjct: 93 LEIGDRVVVSGNKIGTLRYVGTTEFAKGEWAGVELDEPLGKNDGAVAGTRYFQCIQGYGLFAPVHKVIKTGKKETT 168
BLAST of Centrosome-associated protein 350 vs. Ensembl Nematostella
Match: EDO43343 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RZ45]) HSP 1 Score: 72.0182 bits (175), Expect = 6.553e-13 Identity = 31/74 (41.89%), Postives = 47/74 (63.51%), Query Frame = 1
Query: 88 QMINEFQIGDSVLYNSKLEGTVRFIGSTASAKGTFYGIELHTADGRTDGTMDGISYFECKEKHGIFARRSQLTK 309
++ +FQIG+ VL + G V+FIG T A G + GIEL G+ DG++ G+ YF CK + G+FA +++TK
Sbjct: 354 EIARDFQIGEHVLVAGQKPGIVQFIGQTQFASGWWLGIELSNPVGKNDGSVGGVRYFTCKPRFGVFAPVAKVTK 427 HSP 2 Score: 71.633 bits (174), Expect = 7.680e-13 Identity = 32/79 (40.51%), Postives = 47/79 (59.49%), Query Frame = 1
Query: 88 QMINEFQIGDSVLYNSKLEGTVRFIGSTASAKGTFYGIELHTADGRTDGTMDGISYFECKEKHGIFARRSQLTKIQSTE 324
Q NE IG+ V G +RF G T A G + G+EL G+ DG++DG+ YF+C+ HGIFA S++T+ +T+
Sbjct: 223 QDANELTIGERVYIGGTKSGVLRFCGRTEFASGEWVGVELDQPVGKNDGSVDGVQYFQCEPNHGIFAPASKVTRNGTTQ 301
BLAST of Centrosome-associated protein 350 vs. Ensembl Nematostella
Match: EDO30218 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7T1F2]) HSP 1 Score: 55.4546 bits (132), Expect = 7.938e-10 Identity = 22/49 (44.90%), Postives = 32/49 (65.31%), Query Frame = 1
Query: 145 GTVRFIGSTASAKGTFYGIELHTADGRTDGTMDGISYFECKEKHGIFAR 291
G +RFIG+T + G + G+EL A G+ DG++ G+ YF CK + G F R
Sbjct: 3 GVIRFIGATEFSPGPWVGVELDKAGGKNDGSVSGVRYFACKPRFGSFVR 51
BLAST of Centrosome-associated protein 350 vs. Ensembl Nematostella
Match: EDO44433 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RVR2]) HSP 1 Score: 62.7734 bits (151), Expect = 1.107e-9 Identity = 38/114 (33.33%), Postives = 62/114 (54.39%), Query Frame = 1
Query: 109 IGDSVL--YNSKLE-GTVRFIGSTASAKGTFYGIELHTADGRTDGTMDGISYFECKEKHGIFARRSQLTKIQSTEVTSSENEVHDKLLNSCGETRDLTAQTSDKIASHIKTNNI 441
+GD V+ N +L G +RF G+T + G + GI L A G+ DG++ G+ YF+CK+ HGIF ++ ++ V + +E LLN L + + +IA+H NN+
Sbjct: 202 LGDRVVCVLNKRLRTGVLRFTGTTHFSPGEWCGIVLDDACGKNDGSVKGVRYFDCKQDHGIFVHAHKVRALEEVAVKLTISEA--GLLN-------LQQKGNKRIANHHNNNNM 306
BLAST of Centrosome-associated protein 350 vs. Ensembl Nematostella
Match: EDO49101 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RGS4]) HSP 1 Score: 61.6178 bits (148), Expect = 2.367e-9 Identity = 25/65 (38.46%), Postives = 39/65 (60.00%), Query Frame = 1
Query: 145 GTVRFIGSTASAKGTFYGIELHTADGRTDGTMDGISYFECKEKHGIFARRSQLTKIQSTEVTSSE 339
GTV ++G+T A G + G+ L G+ DGT+ G YF C++ +GIF R+SQ+ + S T +
Sbjct: 6 GTVAYVGATQFATGKWIGVVLDEKKGKNDGTVQGKEYFSCEDGYGIFVRQSQIIVLDSNTSTPQQ 70
BLAST of Centrosome-associated protein 350 vs. Ensembl Medaka
Match: dctn1b (dynactin subunit 1 [Source:NCBI gene;Acc:101166919]) HSP 1 Score: 112.849 bits (281), Expect = 1.250e-24 Identity = 169/792 (21.34%), Postives = 336/792 (42.42%), Query Frame = 1
Query: 1246 ELQRELLDAKEREERIKKEFDSYRDMMRSGEEEIEMITIDKEMAEEKLEQVNQDYRNLKKLYEQVLEENSML------KNSDGTSDAKIFIDQTSTIN-KYKNALLELSQSINCYKEENRNL-------NSELDILKELQIFQENESEQLKSKIEKHEKDLKEMKDLVDSTADVEVILDKLTFKNXXXXXXXXXXXXXXXXXXXXXXXXXXVIESKDKKIREFHEECDCLNLIVNEIQNALDKKKIENSELL----KTTNQMNERICXXXXXXXXXXXXXXXXXXXVKKAKAKDRELSS----------------LTFSKQNIEKNEMKRDIENKLKTIEISHKSHQVQLLIQYLPASFSLPGGEHDLIETVQIVDKLIDKISLVLEYIIQKRRLYQQRDNSEKTPENICIQYKLEFLLLIWCGL---LKQLQINIHHSSPEALCQ--------LRSEFKQILQQEQNIDLLIDLMKKQCLDNSRNFSGVLQSIAFFQNFYADRFCYQQIDCNLKMENFISILSKGSECLRNDLSWIDQMLENNVGEQTLKLMDNLNKISTNVQSTMKNTQMYLRHNQRITFDSSVSKSIDGIIFSLMDIVLS----ISDFALQLTDERIFSDEAMCRLTEIFANNRNPLNPTSDNEILFSLNSID---------------------KQVENIV--------SNFKSGVYDADKLNKTFNSAIDTNATNYREKLMGLQALSFEIKLKDEMLALINQELKEKSSQLSEILMQVNFYKQKLQTAVESREIIINQLNQRIYELEA 3387
ELQR+L +AK + + + Y + M + IEM T+DKEMAEE+ E + + +LK+ E++ + +L K SDG + + + Q N + K AL+ + K+E+ L N ELD L+ + E+L+ ++ E+ + E+K+ VD+ E +++ LT +N +E K +++RE + + +N + +E+Q + ++E E+L + +R+ + + + I K E+ + +REL+S F + E + IE +L+ +E++ S QV LL ++P SF GG+HD I + ++ +LI K L+ + +K L SE E + ++ + L GL L LQ +H +AL Q + S + ++ E+++D LIDL+ + LD + + ++I ++Q+ Y+ Q DC +++ + I C+ ++ + L + G++ +L L + T+ + F + + + G + LS +SD L+D R + L E+ A ++P + E L ++ D +Q NIV + + G YD++K ++ A R ++ + L +++ ++ ++ + + LK K +LSE ++++ ++KL ++ + + + ++ R+ E +A
Sbjct: 247 ELQRQLKEAKREAKEALEAKERYTEEMSDTADAIEMATLDKEMAEERAESLQLEVDSLKERVEELTMDLEILKHEIEEKGSDGAASS-FHVKQLEEQNGRLKEALVRMRDLSASEKQEHVKLQKQMEKKNMELDSLR-------GQKEKLQEEMSAAERTIDELKEQVDAALGAEEMVETLTERNLD-------------------------LEEKVRELRETVTDLEAINEMNDELQENARETELELREMLDLGAARVREAEKRVEAAQETVADYQQTINKYRELTAHLQELNRELTSQQEASAELQQQPPADMFDFKIKFAETKAYAKAIEMELRKMEVAQASRQVSLLTSFMPESFLRHGGDHDCILVLLLIPRLICKAELISKQAEEKFEL------SEGCVERVGLRGSVGEQLSFAAGLVYSLSLLQATLHKYE-QALSQCSVNVYKKVGSLYPEMSVHERSLDFLIDLLHRDQLDETVRVEPLTKAIKYYQHLYSIHLADQTEDCTMQLADHIRFTQSALNCMAVEVGRLRAFL--HAGQEKAELAVLLKDLETSCSDIRQ-------------FCKKIRRRMPGTDAPGIPAALSFGPQVSD---ALSDSRKHLTWVVAVLQEVAAAGAQMMSPLGEQEGLSAVKLEDVAFQATEQVYGSQGANTYECLRQSCNIVIATMNKMATAMQEGEYDSEKPQMKNPPPVELQAAALRAEITDAEGLGLKLEDRETVIKELKKSLKIKGEELSEASVRLSLLEKKLDSSSKDADERVEKIQTRLDETQA 980 HSP 2 Score: 67.3958 bits (163), Expect = 1.038e-10 Identity = 30/66 (45.45%), Postives = 41/66 (62.12%), Query Frame = 1
Query: 145 GTVRFIGSTASAKGTFYGIELHTADGRTDGTMDGISYFECKEKHGIFARRSQLTKIQSTEVTSSEN 342
GTV +IG+T A G + GI L G+ DGT+ G YF C+E HGIF R+SQ+ + T T+S +
Sbjct: 51 GTVAYIGTTLFASGKWVGIILDEPKGKNDGTVQGKRYFTCEENHGIFVRQSQIQLVDDTADTTSPD 116
BLAST of Centrosome-associated protein 350 vs. Ensembl Medaka
Match: dctn1b (dynactin subunit 1 [Source:NCBI gene;Acc:101166919]) HSP 1 Score: 112.849 bits (281), Expect = 1.340e-24 Identity = 169/792 (21.34%), Postives = 336/792 (42.42%), Query Frame = 1
Query: 1246 ELQRELLDAKEREERIKKEFDSYRDMMRSGEEEIEMITIDKEMAEEKLEQVNQDYRNLKKLYEQVLEENSML------KNSDGTSDAKIFIDQTSTIN-KYKNALLELSQSINCYKEENRNL-------NSELDILKELQIFQENESEQLKSKIEKHEKDLKEMKDLVDSTADVEVILDKLTFKNXXXXXXXXXXXXXXXXXXXXXXXXXXVIESKDKKIREFHEECDCLNLIVNEIQNALDKKKIENSELL----KTTNQMNERICXXXXXXXXXXXXXXXXXXXVKKAKAKDRELSS----------------LTFSKQNIEKNEMKRDIENKLKTIEISHKSHQVQLLIQYLPASFSLPGGEHDLIETVQIVDKLIDKISLVLEYIIQKRRLYQQRDNSEKTPENICIQYKLEFLLLIWCGL---LKQLQINIHHSSPEALCQ--------LRSEFKQILQQEQNIDLLIDLMKKQCLDNSRNFSGVLQSIAFFQNFYADRFCYQQIDCNLKMENFISILSKGSECLRNDLSWIDQMLENNVGEQTLKLMDNLNKISTNVQSTMKNTQMYLRHNQRITFDSSVSKSIDGIIFSLMDIVLS----ISDFALQLTDERIFSDEAMCRLTEIFANNRNPLNPTSDNEILFSLNSID---------------------KQVENIV--------SNFKSGVYDADKLNKTFNSAIDTNATNYREKLMGLQALSFEIKLKDEMLALINQELKEKSSQLSEILMQVNFYKQKLQTAVESREIIINQLNQRIYELEA 3387
ELQR+L +AK + + + Y + M + IEM T+DKEMAEE+ E + + +LK+ E++ + +L K SDG + + + Q N + K AL+ + K+E+ L N ELD L+ + E+L+ ++ E+ + E+K+ VD+ E +++ LT +N +E K +++RE + + +N + +E+Q + ++E E+L + +R+ + + + I K E+ + +REL+S F + E + IE +L+ +E++ S QV LL ++P SF GG+HD I + ++ +LI K L+ + +K L SE E + ++ + L GL L LQ +H +AL Q + S + ++ E+++D LIDL+ + LD + + ++I ++Q+ Y+ Q DC +++ + I C+ ++ + L + G++ +L L + T+ + F + + + G + LS +SD L+D R + L E+ A ++P + E L ++ D +Q NIV + + G YD++K ++ A R ++ + L +++ ++ ++ + + LK K +LSE ++++ ++KL ++ + + + ++ R+ E +A
Sbjct: 266 ELQRQLKEAKREAKEALEAKERYTEEMSDTADAIEMATLDKEMAEERAESLQLEVDSLKERVEELTMDLEILKHEIEEKGSDGAASS-FHVKQLEEQNGRLKEALVRMRDLSASEKQEHVKLQKQMEKKNMELDSLR-------GQKEKLQEEMSAAERTIDELKEQVDAALGAEEMVETLTERNLD-------------------------LEEKVRELRETVTDLEAINEMNDELQENARETELELREMLDLGAARVREAEKRVEAAQETVADYQQTINKYRELTAHLQELNRELTSQQEASAELQQQPPADMFDFKIKFAETKAYAKAIEMELRKMEVAQASRQVSLLTSFMPESFLRHGGDHDCILVLLLIPRLICKAELISKQAEEKFEL------SEGCVERVGLRGSVGEQLSFAAGLVYSLSLLQATLHKYE-QALSQCSVNVYKKVGSLYPEMSVHERSLDFLIDLLHRDQLDETVRVEPLTKAIKYYQHLYSIHLADQTEDCTMQLADHIRFTQSALNCMAVEVGRLRAFL--HAGQEKAELAVLLKDLETSCSDIRQ-------------FCKKIRRRMPGTDAPGIPAALSFGPQVSDA---LSDSRKHLTWVVAVLQEVAAAGAQMMSPLGEQEGLSAVKLEDVAFQATEQVYGSQGANTYECLRQSCNIVIATMNKMATAMQEGEYDSEKPQMKNPPPVELQAAALRAEITDAEGLGLKLEDRETVIKELKKSLKIKGEELSEASVRLSLLEKKLDSSSKDADERVEKIQTRLDETQA 999 HSP 2 Score: 67.781 bits (164), Expect = 9.396e-11 Identity = 30/66 (45.45%), Postives = 41/66 (62.12%), Query Frame = 1
Query: 145 GTVRFIGSTASAKGTFYGIELHTADGRTDGTMDGISYFECKEKHGIFARRSQLTKIQSTEVTSSEN 342
GTV +IG+T A G + GI L G+ DGT+ G YF C+E HGIF R+SQ+ + T T+S +
Sbjct: 44 GTVAYIGTTLFASGKWVGIILDEPKGKNDGTVQGKRYFTCEENHGIFVRQSQIQLVDDTADTTSPD 109
BLAST of Centrosome-associated protein 350 vs. Ensembl Medaka
Match: dctn1b (dynactin subunit 1 [Source:NCBI gene;Acc:101166919]) HSP 1 Score: 112.849 bits (281), Expect = 1.405e-24 Identity = 169/792 (21.34%), Postives = 336/792 (42.42%), Query Frame = 1
Query: 1246 ELQRELLDAKEREERIKKEFDSYRDMMRSGEEEIEMITIDKEMAEEKLEQVNQDYRNLKKLYEQVLEENSML------KNSDGTSDAKIFIDQTSTIN-KYKNALLELSQSINCYKEENRNL-------NSELDILKELQIFQENESEQLKSKIEKHEKDLKEMKDLVDSTADVEVILDKLTFKNXXXXXXXXXXXXXXXXXXXXXXXXXXVIESKDKKIREFHEECDCLNLIVNEIQNALDKKKIENSELL----KTTNQMNERICXXXXXXXXXXXXXXXXXXXVKKAKAKDRELSS----------------LTFSKQNIEKNEMKRDIENKLKTIEISHKSHQVQLLIQYLPASFSLPGGEHDLIETVQIVDKLIDKISLVLEYIIQKRRLYQQRDNSEKTPENICIQYKLEFLLLIWCGL---LKQLQINIHHSSPEALCQ--------LRSEFKQILQQEQNIDLLIDLMKKQCLDNSRNFSGVLQSIAFFQNFYADRFCYQQIDCNLKMENFISILSKGSECLRNDLSWIDQMLENNVGEQTLKLMDNLNKISTNVQSTMKNTQMYLRHNQRITFDSSVSKSIDGIIFSLMDIVLS----ISDFALQLTDERIFSDEAMCRLTEIFANNRNPLNPTSDNEILFSLNSID---------------------KQVENIV--------SNFKSGVYDADKLNKTFNSAIDTNATNYREKLMGLQALSFEIKLKDEMLALINQELKEKSSQLSEILMQVNFYKQKLQTAVESREIIINQLNQRIYELEA 3387
ELQR+L +AK + + + Y + M + IEM T+DKEMAEE+ E + + +LK+ E++ + +L K SDG + + + Q N + K AL+ + K+E+ L N ELD L+ + E+L+ ++ E+ + E+K+ VD+ E +++ LT +N +E K +++RE + + +N + +E+Q + ++E E+L + +R+ + + + I K E+ + +REL+S F + E + IE +L+ +E++ S QV LL ++P SF GG+HD I + ++ +LI K L+ + +K L SE E + ++ + L GL L LQ +H +AL Q + S + ++ E+++D LIDL+ + LD + + ++I ++Q+ Y+ Q DC +++ + I C+ ++ + L + G++ +L L + T+ + F + + + G + LS +SD L+D R + L E+ A ++P + E L ++ D +Q NIV + + G YD++K ++ A R ++ + L +++ ++ ++ + + LK K +LSE ++++ ++KL ++ + + + ++ R+ E +A
Sbjct: 259 ELQRQLKEAKREAKEALEAKERYTEEMSDTADAIEMATLDKEMAEERAESLQLEVDSLKERVEELTMDLEILKHEIEEKGSDGAASS-FHVKQLEEQNGRLKEALVRMRDLSASEKQEHVKLQKQMEKKNMELDSLR-------GQKEKLQEEMSAAERTIDELKEQVDAALGAEEMVETLTERNLD-------------------------LEEKVRELRETVTDLEAINEMNDELQENARETELELREMLDLGAARVREAEKRVEAAQETVADYQQTINKYRELTAHLQELNRELTSQQEASAELQQQPPADMFDFKIKFAETKAYAKAIEMELRKMEVAQASRQVSLLTSFMPESFLRHGGDHDCILVLLLIPRLICKAELISKQAEEKFEL------SEGCVERVGLRGSVGEQLSFAAGLVYSLSLLQATLHKYE-QALSQCSVNVYKKVGSLYPEMSVHERSLDFLIDLLHRDQLDETVRVEPLTKAIKYYQHLYSIHLADQTEDCTMQLADHIRFTQSALNCMAVEVGRLRAFL--HAGQEKAELAVLLKDLETSCSDIRQ-------------FCKKIRRRMPGTDAPGIPAALSFGPQVSDA---LSDSRKHLTWVVAVLQEVAAAGAQMMSPLGEQEGLSAVKLEDVAFQATEQVYGSQGANTYECLRQSCNIVIATMNKMATAMQEGEYDSEKPQMKNPPPVELQAAALRAEITDAEGLGLKLEDRETVIKELKKSLKIKGEELSEASVRLSLLEKKLDSSSKDADERVEKIQTRLDETQA 992 HSP 2 Score: 67.781 bits (164), Expect = 8.694e-11 Identity = 30/66 (45.45%), Postives = 41/66 (62.12%), Query Frame = 1
Query: 145 GTVRFIGSTASAKGTFYGIELHTADGRTDGTMDGISYFECKEKHGIFARRSQLTKIQSTEVTSSEN 342
GTV +IG+T A G + GI L G+ DGT+ G YF C+E HGIF R+SQ+ + T T+S +
Sbjct: 44 GTVAYIGTTLFASGKWVGIILDEPKGKNDGTVQGKRYFTCEENHGIFVRQSQIQLVDDTADTTSPD 109
BLAST of Centrosome-associated protein 350 vs. Ensembl Medaka
Match: dctn1b (dynactin subunit 1 [Source:NCBI gene;Acc:101166919]) HSP 1 Score: 112.849 bits (281), Expect = 1.492e-24 Identity = 169/792 (21.34%), Postives = 336/792 (42.42%), Query Frame = 1
Query: 1246 ELQRELLDAKEREERIKKEFDSYRDMMRSGEEEIEMITIDKEMAEEKLEQVNQDYRNLKKLYEQVLEENSML------KNSDGTSDAKIFIDQTSTIN-KYKNALLELSQSINCYKEENRNL-------NSELDILKELQIFQENESEQLKSKIEKHEKDLKEMKDLVDSTADVEVILDKLTFKNXXXXXXXXXXXXXXXXXXXXXXXXXXVIESKDKKIREFHEECDCLNLIVNEIQNALDKKKIENSELL----KTTNQMNERICXXXXXXXXXXXXXXXXXXXVKKAKAKDRELSS----------------LTFSKQNIEKNEMKRDIENKLKTIEISHKSHQVQLLIQYLPASFSLPGGEHDLIETVQIVDKLIDKISLVLEYIIQKRRLYQQRDNSEKTPENICIQYKLEFLLLIWCGL---LKQLQINIHHSSPEALCQ--------LRSEFKQILQQEQNIDLLIDLMKKQCLDNSRNFSGVLQSIAFFQNFYADRFCYQQIDCNLKMENFISILSKGSECLRNDLSWIDQMLENNVGEQTLKLMDNLNKISTNVQSTMKNTQMYLRHNQRITFDSSVSKSIDGIIFSLMDIVLS----ISDFALQLTDERIFSDEAMCRLTEIFANNRNPLNPTSDNEILFSLNSID---------------------KQVENIV--------SNFKSGVYDADKLNKTFNSAIDTNATNYREKLMGLQALSFEIKLKDEMLALINQELKEKSSQLSEILMQVNFYKQKLQTAVESREIIINQLNQRIYELEA 3387
ELQR+L +AK + + + Y + M + IEM T+DKEMAEE+ E + + +LK+ E++ + +L K SDG + + + Q N + K AL+ + K+E+ L N ELD L+ + E+L+ ++ E+ + E+K+ VD+ E +++ LT +N +E K +++RE + + +N + +E+Q + ++E E+L + +R+ + + + I K E+ + +REL+S F + E + IE +L+ +E++ S QV LL ++P SF GG+HD I + ++ +LI K L+ + +K L SE E + ++ + L GL L LQ +H +AL Q + S + ++ E+++D LIDL+ + LD + + ++I ++Q+ Y+ Q DC +++ + I C+ ++ + L + G++ +L L + T+ + F + + + G + LS +SD L+D R + L E+ A ++P + E L ++ D +Q NIV + + G YD++K ++ A R ++ + L +++ ++ ++ + + LK K +LSE ++++ ++KL ++ + + + ++ R+ E +A
Sbjct: 260 ELQRQLKEAKREAKEALEAKERYTEEMSDTADAIEMATLDKEMAEERAESLQLEVDSLKERVEELTMDLEILKHEIEEKGSDGAASS-FHVKQLEEQNGRLKEALVRMRDLSASEKQEHVKLQKQMEKKNMELDSLR-------GQKEKLQEEMSAAERTIDELKEQVDAALGAEEMVETLTERNLD-------------------------LEEKVRELRETVTDLEAINEMNDELQENARETELELREMLDLGAARVREAEKRVEAAQETVADYQQTINKYRELTAHLQELNRELTSQQEASAELQQQPPADMFDFKIKFAETKAYAKAIEMELRKMEVAQASRQVSLLTSFMPESFLRHGGDHDCILVLLLIPRLICKAELISKQAEEKFEL------SEGCVERVGLRGSVGEQLSFAAGLVYSLSLLQATLHKYE-QALSQCSVNVYKKVGSLYPEMSVHERSLDFLIDLLHRDQLDETVRVEPLTKAIKYYQHLYSIHLADQTEDCTMQLADHIRFTQSALNCMAVEVGRLRAFL--HAGQEKAELAVLLKDLETSCSDIRQ-------------FCKKIRRRMPGTDAPGIPAALSFGPQVSDA---LSDSRKHLTWVVAVLQEVAAAGAQMMSPLGEQEGLSAVKLEDVAFQATEQVYGSQGANTYECLRQSCNIVIATMNKMATAMQEGEYDSEKPQMKNPPPVELQAAALRAEITDAEGLGLKLEDRETVIKELKKSLKIKGEELSEASVRLSLLEKKLDSSSKDADERVEKIQTRLDETQA 993 HSP 2 Score: 67.781 bits (164), Expect = 9.071e-11 Identity = 30/66 (45.45%), Postives = 41/66 (62.12%), Query Frame = 1
Query: 145 GTVRFIGSTASAKGTFYGIELHTADGRTDGTMDGISYFECKEKHGIFARRSQLTKIQSTEVTSSEN 342
GTV +IG+T A G + GI L G+ DGT+ G YF C+E HGIF R+SQ+ + T T+S +
Sbjct: 44 GTVAYIGTTLFASGKWVGIILDEPKGKNDGTVQGKRYFTCEENHGIFVRQSQIQLVDDTADTTSPD 109
BLAST of Centrosome-associated protein 350 vs. Ensembl Medaka
Match: dctn1b (dynactin subunit 1 [Source:NCBI gene;Acc:101166919]) HSP 1 Score: 112.849 bits (281), Expect = 1.517e-24 Identity = 169/792 (21.34%), Postives = 336/792 (42.42%), Query Frame = 1
Query: 1246 ELQRELLDAKEREERIKKEFDSYRDMMRSGEEEIEMITIDKEMAEEKLEQVNQDYRNLKKLYEQVLEENSML------KNSDGTSDAKIFIDQTSTIN-KYKNALLELSQSINCYKEENRNL-------NSELDILKELQIFQENESEQLKSKIEKHEKDLKEMKDLVDSTADVEVILDKLTFKNXXXXXXXXXXXXXXXXXXXXXXXXXXVIESKDKKIREFHEECDCLNLIVNEIQNALDKKKIENSELL----KTTNQMNERICXXXXXXXXXXXXXXXXXXXVKKAKAKDRELSS----------------LTFSKQNIEKNEMKRDIENKLKTIEISHKSHQVQLLIQYLPASFSLPGGEHDLIETVQIVDKLIDKISLVLEYIIQKRRLYQQRDNSEKTPENICIQYKLEFLLLIWCGL---LKQLQINIHHSSPEALCQ--------LRSEFKQILQQEQNIDLLIDLMKKQCLDNSRNFSGVLQSIAFFQNFYADRFCYQQIDCNLKMENFISILSKGSECLRNDLSWIDQMLENNVGEQTLKLMDNLNKISTNVQSTMKNTQMYLRHNQRITFDSSVSKSIDGIIFSLMDIVLS----ISDFALQLTDERIFSDEAMCRLTEIFANNRNPLNPTSDNEILFSLNSID---------------------KQVENIV--------SNFKSGVYDADKLNKTFNSAIDTNATNYREKLMGLQALSFEIKLKDEMLALINQELKEKSSQLSEILMQVNFYKQKLQTAVESREIIINQLNQRIYELEA 3387
ELQR+L +AK + + + Y + M + IEM T+DKEMAEE+ E + + +LK+ E++ + +L K SDG + + + Q N + K AL+ + K+E+ L N ELD L+ + E+L+ ++ E+ + E+K+ VD+ E +++ LT +N +E K +++RE + + +N + +E+Q + ++E E+L + +R+ + + + I K E+ + +REL+S F + E + IE +L+ +E++ S QV LL ++P SF GG+HD I + ++ +LI K L+ + +K L SE E + ++ + L GL L LQ +H +AL Q + S + ++ E+++D LIDL+ + LD + + ++I ++Q+ Y+ Q DC +++ + I C+ ++ + L + G++ +L L + T+ + F + + + G + LS +SD L+D R + L E+ A ++P + E L ++ D +Q NIV + + G YD++K ++ A R ++ + L +++ ++ ++ + + LK K +LSE ++++ ++KL ++ + + + ++ R+ E +A
Sbjct: 259 ELQRQLKEAKREAKEALEAKERYTEEMSDTADAIEMATLDKEMAEERAESLQLEVDSLKERVEELTMDLEILKHEIEEKGSDGAASS-FHVKQLEEQNGRLKEALVRMRDLSASEKQEHVKLQKQMEKKNMELDSLR-------GQKEKLQEEMSAAERTIDELKEQVDAALGAEEMVETLTERNLD-------------------------LEEKVRELRETVTDLEAINEMNDELQENARETELELREMLDLGAARVREAEKRVEAAQETVADYQQTINKYRELTAHLQELNRELTSQQEASAELQQQPPADMFDFKIKFAETKAYAKAIEMELRKMEVAQASRQVSLLTSFMPESFLRHGGDHDCILVLLLIPRLICKAELISKQAEEKFEL------SEGCVERVGLRGSVGEQLSFAAGLVYSLSLLQATLHKYE-QALSQCSVNVYKKVGSLYPEMSVHERSLDFLIDLLHRDQLDETVRVEPLTKAIKYYQHLYSIHLADQTEDCTMQLADHIRFTQSALNCMAVEVGRLRAFL--HAGQEKAELAVLLKDLETSCSDIRQ-------------FCKKIRRRMPGTDAPGIPAALSFGPQVSDA---LSDSRKHLTWVVAVLQEVAAAGAQMMSPLGEQEGLSAVKLEDVAFQATEQVYGSQGANTYECLRQSCNIVIATMNKMATAMQEGEYDSEKPQMKNPPPVELQAAALRAEITDAEGLGLKLEDRETVIKELKKSLKIKGEELSEASVRLSLLEKKLDSSSKDADERVEKIQTRLDETQA 992 HSP 2 Score: 67.781 bits (164), Expect = 8.548e-11 Identity = 30/66 (45.45%), Postives = 41/66 (62.12%), Query Frame = 1
Query: 145 GTVRFIGSTASAKGTFYGIELHTADGRTDGTMDGISYFECKEKHGIFARRSQLTKIQSTEVTSSEN 342
GTV +IG+T A G + GI L G+ DGT+ G YF C+E HGIF R+SQ+ + T T+S +
Sbjct: 44 GTVAYIGTTLFASGKWVGIILDEPKGKNDGTVQGKRYFTCEENHGIFVRQSQIQLVDDTADTTSPD 109
BLAST of Centrosome-associated protein 350 vs. Planmine SMEST
Match: SMESG000069358.1 (SMESG000069358.1) HSP 1 Score: 2358.95 bits (6112), Expect = 0.000e+0 Identity = 1244/1255 (99.12%), Postives = 1247/1255 (99.36%), Query Frame = 1
Query: 91 MINEFQIGDSVLYNSKLEGTVRFIGSTASAKGTFYGIELHTADGRTDGTMDGISYFECKEKHGIFARRSQLTKIQSTEVTSSENEVHDKLLNSCGETRDLTAQTSDKIASHIKTNNIVTSVPSIINSTYRENLETTFDSKFAKDFRRNTISSTLKTIENHVQSSFDITTQESATKEISKQESNLVHKKEIIIEDLTPMKKHESASQIDNHSKLKFHRNSVDLKLKSHENLKQNQLELEIPKNYRRNTVGNNEIETKFRHNFGIKEPVHQHLSTIFEKNPNDKQLNNSNVPNKLMATQETANQIENGKQQTKITSFKYARRNTLASKSVVCESRQGKENQLIHPRNTVSXXXXXXXXXXXXXXXXTLQILKKKEYKRCGDLEKLNNELQRELLDAKEREERIKKEFDSYRDMMRSGEEEIEMITIDKEMAEEKLEQVNQDYRNLKKLYEQVLEENSMLKNSDGTSDAKIFIDQTSTINKYKNALLELSQSINCYKEENRNLNSELDILKELQIFQENESEQLKSKIEKHEKDLKEMKDLVDSTADVEVILDKLTFKNXXXXXXXXXXXXXXXXXXXXXXXXXXVIESKDKKIREFHEECDCLNLIVNEIQNALDKKKIENSELLKTTNQMNERICXXXXXXXXXXXXXXXXXXXVKKAKAKDRELSSLTFSKQNIEKNEMKRDIENKLKTIEISHKSHQVQLLIQYLPASFSLPGGEHDLIETVQIVDKLIDKISLVLEYIIQKRRLYQQRDNSEKTPENICIQYKLEFLLLIWCGLLKQLQINIHHSSPEALCQLRSEFKQILQQEQNIDLLIDLMKKQCLDNSRNFSGVLQSIAFFQNFYADRFCYQQIDCNLKMENFISILSKGSECLRNDLSWIDQMLENNVGEQTLKLMDNLNKISTNVQSTMKNTQMYLRHNQRITFDSSVSKSIDGIIFSLMDIVLSISDFALQLTDERIFSDEAMCRLTEIFANNRNPLNPTSDNEILFSLNSIDKQVENIVSNFKSGVYDADKLNKTFNSAIDTNATNYREKLMGLQALSFEIKLKDEMLALINQELKEKSSQLSEILMQVNFYKQKLQTAVESREIIINQLNQRIYELEANAAKRNETEKLSEFESETLKISCEPISHLSVSNEENFKSCSIDINDYQNEIRNLTIIVKYLMRKLHKSNAIKSDKRLQELKPIKTQTFISDKELNLLMQRAVTINRDIYESLSNVKIPDLSSRKDIKQFSEKSIIFSKLKNQSEKLIIDGMKKCNQ 3855
MINEFQIGDSVLYNSKLEGTVRFIGSTASAKGTFYGIELHTADGRTDGTMDGISYFECKEKHGIFARRSQLTKIQSTEVTSSE+EVHDKLLNSCGE RDLTAQTSDKIASHIKTN+IVTSVPSIINSTYRENLETTFDSKFAKDFRRNTISSTLKTIENHVQSSFDITTQESATKEISKQESNLVHKKEIIIEDLTPMKKHESASQIDN+SKLKFHRNSVDLKLKSHENLK NQLELEIPKNYRRNTVGNNEIETKFRHNFGIKEPVHQHLSTIFEKNPNDKQLNNSNVPNKLMATQETANQIENGKQQTKITSFKYARRNTLASKSVVCESRQGKENQLIHPRNTVSNLDKDKEIKDLKEKNETLQILKKKEYKRCGDLEKLNNELQRELLDAKEREERIKKEFDSYRDMMRSGEEEIEMITIDKEMAEEKLEQVNQDYRNLKKLYEQVLEENSMLKNSDGTSDAKIFIDQTSTINKYKNALLELSQSINCYKEENRNLNSELDILKELQIFQENESEQLKSKIEKHEKDLKEMKDLVDSTADVEVILDKLTFKNEYLEKELKKLKKRLIELDKLEDDRLEVIESKDKKIREFHEECDCLNLIVNEIQNALDKKKIENSELLKTTNQMNERICLLTNELKEKELEIQKQNEIVKKAKAKDRELSSLTFSKQNIEKNEMKRDIENKLKTIEISHKSHQVQLLIQYLPASFSLPGGEHDLIETVQIVDKLIDKISLVLEYIIQKRRLYQQRDNSEKTPENICIQYKLEFLLLIWCGLLKQLQINIHHSSPEALCQLRSEFKQILQQEQNIDLLIDLMKKQCLDNSRNFSGVLQSI FFQNFYADRFCYQQIDCNLKMENFISILSKGSECLRNDLSWIDQMLENNVGEQTLKLMDNLNKISTNVQSTMKNTQMYLRHNQRITFDSSVSKSIDGIIF LMDIVLSISDFALQLTDERIFSDEAMCRLTEIFANNRNPLNPTSDNEILFSLNSIDKQVENIVSNFKSGVYDADKLNKTFNSAIDTNATNYREKLMGLQALSFEIKLKDEMLALINQELKEKSSQLSEILMQVNFYKQKLQTAVESREIIINQLNQRIYELEANAAKRNETEKLSEFESE LKISCEPISH SVSNEENFKSCSIDINDYQNEIRNLTIIVKYLM KLHKSNAIKSD RLQELKPIKTQTFISDKELNLLMQRAVTINRDIYESLSNVKIPDLSSRKDIKQFSEKSIIFSKLKNQSEKLIIDGMKKCNQ
Sbjct: 1 MINEFQIGDSVLYNSKLEGTVRFIGSTASAKGTFYGIELHTADGRTDGTMDGISYFECKEKHGIFARRSQLTKIQSTEVTSSESEVHDKLLNSCGENRDLTAQTSDKIASHIKTNDIVTSVPSIINSTYRENLETTFDSKFAKDFRRNTISSTLKTIENHVQSSFDITTQESATKEISKQESNLVHKKEIIIEDLTPMKKHESASQIDNNSKLKFHRNSVDLKLKSHENLKPNQLELEIPKNYRRNTVGNNEIETKFRHNFGIKEPVHQHLSTIFEKNPNDKQLNNSNVPNKLMATQETANQIENGKQQTKITSFKYARRNTLASKSVVCESRQGKENQLIHPRNTVSNLDKDKEIKDLKEKNETLQILKKKEYKRCGDLEKLNNELQRELLDAKEREERIKKEFDSYRDMMRSGEEEIEMITIDKEMAEEKLEQVNQDYRNLKKLYEQVLEENSMLKNSDGTSDAKIFIDQTSTINKYKNALLELSQSINCYKEENRNLNSELDILKELQIFQENESEQLKSKIEKHEKDLKEMKDLVDSTADVEVILDKLTFKNEYLEKELKKLKKRLIELDKLEDDRLEVIESKDKKIREFHEECDCLNLIVNEIQNALDKKKIENSELLKTTNQMNERICLLTNELKEKELEIQKQNEIVKKAKAKDRELSSLTFSKQNIEKNEMKRDIENKLKTIEISHKSHQVQLLIQYLPASFSLPGGEHDLIETVQIVDKLIDKISLVLEYIIQKRRLYQQRDNSEKTPENICIQYKLEFLLLIWCGLLKQLQINIHHSSPEALCQLRSEFKQILQQEQNIDLLIDLMKKQCLDNSRNFSGVLQSIEFFQNFYADRFCYQQIDCNLKMENFISILSKGSECLRNDLSWIDQMLENNVGEQTLKLMDNLNKISTNVQSTMKNTQMYLRHNQRITFDSSVSKSIDGIIFLLMDIVLSISDFALQLTDERIFSDEAMCRLTEIFANNRNPLNPTSDNEILFSLNSIDKQVENIVSNFKSGVYDADKLNKTFNSAIDTNATNYREKLMGLQALSFEIKLKDEMLALINQELKEKSSQLSEILMQVNFYKQKLQTAVESREIIINQLNQRIYELEANAAKRNETEKLSEFESEPLKISCEPISHSSVSNEENFKSCSIDINDYQNEIRNLTIIVKYLMSKLHKSNAIKSDNRLQELKPIKTQTFISDKELNLLMQRAVTINRDIYESLSNVKIPDLSSRKDIKQFSEKSIIFSKLKNQSEKLIIDGMKKCNQ 1255 HSP 2 Score: 108.997 bits (271), Expect = 1.595e-23 Identity = 50/50 (100.00%), Postives = 50/50 (100.00%), Query Frame = 3
Query: 3855 KLVYFDSPNSACTNNSIGLIRFDRNSVNDQSMKSVSIDNWSLKKLEELFC 4004
KLVYFDSPNSACTNNSIGLIRFDRNSVNDQSMKSVSIDNWSLKKLEELFC
Sbjct: 1256 KLVYFDSPNSACTNNSIGLIRFDRNSVNDQSMKSVSIDNWSLKKLEELFC 1305
BLAST of Centrosome-associated protein 350 vs. Planmine SMEST
Match: SMESG000029463.1 (SMESG000029463.1) HSP 1 Score: 154.066 bits (388), Expect = 2.130e-37 Identity = 158/615 (25.69%), Postives = 292/615 (47.48%), Query Frame = 1
Query: 2137 IENKLKTIEISHKSHQVQLLIQYLPASFSLPGGEHDLIETVQIVDKLIDKISLVLEYIIQKRRLYQQRDNSEKTPENI----CIQYKLEFLLLIWCGLLKQLQINIHHSSPEALCQLRSEFKQILQQEQNIDLLIDLMKKQCLDNSRNFSGVLQSIAFFQNFYADRFCYQQIDCNLKMENFISILSKGSECLRNDLSW-IDQMLENNV-GEQTLKLMDNLNKISTNVQSTMKNTQMYLRHNQRITFDSSVSKSIDGIIFSLMDIVLSISDFALQLT------DERIFSDEAMCRLTEIFANNRNPLNPTSDNEILFSLNSIDKQVENIVSNFKSGVYDADKLNKTFNSAIDTNATNYREKLMGLQALSFEIKLKDEMLALINQELKEKSSQLSEILMQVNFYKQKLQTAVESREIIINQLNQRIYELEANAAKRNETEKLSEFESETLKISCEPISHLSVSNEE-----------NF----------------KSCSIDINDYQNEIRNLTIIVKYLMRKLHKSNAIKSDKRLQELKPI------------KTQTFISDKEL-NLLMQRAVTINRDIYESLSNVKIPDLSSRKDIKQFSEKSIIFSKLKNQSEKL 3825
IEN+L+ +++S S VQ+L ++LP F G ++D I + ++DKLI KI + I ++ L +NI +KL +LL W +L+ + + +L S F ++ E+++D LIDL++K LD + + + +SI +FQ FY + DC +KM +F+ I+ GS+ + + I+ M+++N+ ++ + + L + +++S +N + +L + + F+S +S ++D + L I I+ + L+L D + + ++ + E F R N +S I + +I K NI + + G YD + I ATN++ +L L+ ++++ KDE L LK K +LSE +++N ++KL ++ ++ II +L Q++ + +A ++ EK + SE L+ I+HL + EE NF S +I+ + +EI+ L I+ L + + + + K Q+LKP+ + + I E NL + + + RDIY LS+VKI DLS R K++ + +++K Q EKL
Sbjct: 490 IENELQKLDVSQSSSHVQMLERFLPDKFFKTGADNDSIMMILLIDKLIFKIEFLTNQIKERFLLSPLEPTESGVAKNINDSTAYYHKLIYLLSTWYIILRHYKKTLSSCQLSTFSRLGSLFIEMSPNEKSVDYLIDLLRKGNLDENSSLEPLERSINYFQTFYQVHLINEPPDCLIKMNDFVKIMLGGSDAIEYCCKYAIEFMVKHNMEASESYEFLVRLQQFGLDLKSNTRNIRKHLLKSPSLQFNSGLSTNLDKCVTDLSAITKIITSYCLELATVSDEDDAKSVNMSSLYKYIEKFMEIR---NLSSTLPIFTNTENILKISANISDSMEHGEYDYEGTAVKTEEPIVIIATNFKNELSDLENTCYKLEHKDEELRQAKLNLKLKCDELSENSVRLNIVEKKLSINIKEKDEIIERLEQKLEQTKAALVRK---EKELDQTSEALQ---SDINHLEMQREELKKQLKETKKRNFFDNINISTSKIADQVDSGSSQEISAFLSEIQTLRTIIHNLRNENIRLRSQITSKHAQKLKPLSIPISLNTPNANRNSSLIKKMEYANLTITSSENLTRDIYSHLSSVKIIDLSIRHPEKEYLNELSAKTRIKLQFEKL 1095 HSP 2 Score: 96.2857 bits (238), Expect = 1.264e-19 Identity = 39/84 (46.43%), Postives = 58/84 (69.05%), Query Frame = 1
Query: 94 INEFQIGDSVLYNSKLEGTVRFIGSTASAKGTFYGIELHTADGRTDGTMDGISYFECKEKHGIFARRSQLTKIQSTEVTSSENE 345
+++F+I D VLYN L+GTV FIG+T A G +YG++L + G+ DG++ G SYF+C + HGIF R +QL K+ E T++ E
Sbjct: 1 MSDFKINDIVLYNGTLKGTVEFIGTTHFASGVWYGVKLDSPKGKNDGSVAGKSYFKCDKNHGIFVRNTQLAKVDGDESTNTSAE 84
BLAST of Centrosome-associated protein 350 vs. Planmine SMEST
Match: SMESG000029463.1 (SMESG000029463.1) HSP 1 Score: 154.066 bits (388), Expect = 2.182e-37 Identity = 158/615 (25.69%), Postives = 292/615 (47.48%), Query Frame = 1
Query: 2137 IENKLKTIEISHKSHQVQLLIQYLPASFSLPGGEHDLIETVQIVDKLIDKISLVLEYIIQKRRLYQQRDNSEKTPENI----CIQYKLEFLLLIWCGLLKQLQINIHHSSPEALCQLRSEFKQILQQEQNIDLLIDLMKKQCLDNSRNFSGVLQSIAFFQNFYADRFCYQQIDCNLKMENFISILSKGSECLRNDLSW-IDQMLENNV-GEQTLKLMDNLNKISTNVQSTMKNTQMYLRHNQRITFDSSVSKSIDGIIFSLMDIVLSISDFALQLT------DERIFSDEAMCRLTEIFANNRNPLNPTSDNEILFSLNSIDKQVENIVSNFKSGVYDADKLNKTFNSAIDTNATNYREKLMGLQALSFEIKLKDEMLALINQELKEKSSQLSEILMQVNFYKQKLQTAVESREIIINQLNQRIYELEANAAKRNETEKLSEFESETLKISCEPISHLSVSNEE-----------NF----------------KSCSIDINDYQNEIRNLTIIVKYLMRKLHKSNAIKSDKRLQELKPI------------KTQTFISDKEL-NLLMQRAVTINRDIYESLSNVKIPDLSSRKDIKQFSEKSIIFSKLKNQSEKL 3825
IEN+L+ +++S S VQ+L ++LP F G ++D I + ++DKLI KI + I ++ L +NI +KL +LL W +L+ + + +L S F ++ E+++D LIDL++K LD + + + +SI +FQ FY + DC +KM +F+ I+ GS+ + + I+ M+++N+ ++ + + L + +++S +N + +L + + F+S +S ++D + L I I+ + L+L D + + ++ + E F R N +S I + +I K NI + + G YD + I ATN++ +L L+ ++++ KDE L LK K +LSE +++N ++KL ++ ++ II +L Q++ + +A ++ EK + SE L+ I+HL + EE NF S +I+ + +EI+ L I+ L + + + + K Q+LKP+ + + I E NL + + + RDIY LS+VKI DLS R K++ + +++K Q EKL
Sbjct: 503 IENELQKLDVSQSSSHVQMLERFLPDKFFKTGADNDSIMMILLIDKLIFKIEFLTNQIKERFLLSPLEPTESGVAKNINDSTAYYHKLIYLLSTWYIILRHYKKTLSSCQLSTFSRLGSLFIEMSPNEKSVDYLIDLLRKGNLDENSSLEPLERSINYFQTFYQVHLINEPPDCLIKMNDFVKIMLGGSDAIEYCCKYAIEFMVKHNMEASESYEFLVRLQQFGLDLKSNTRNIRKHLLKSPSLQFNSGLSTNLDKCVTDLSAITKIITSYCLELATVSDEDDAKSVNMSSLYKYIEKFMEIR---NLSSTLPIFTNTENILKISANISDSMEHGEYDYEGTAVKTEEPIVIIATNFKNELSDLENTCYKLEHKDEELRQAKLNLKLKCDELSENSVRLNIVEKKLSINIKEKDEIIERLEQKLEQTKAALVRK---EKELDQTSEALQ---SDINHLEMQREELKKQLKETKKRNFFDNINISTSKIADQVDSGSSQEISAFLSEIQTLRTIIHNLRNENIRLRSQITSKHAQKLKPLSIPISLNTPNANRNSSLIKKMEYANLTITSSENLTRDIYSHLSSVKIIDLSIRHPEKEYLNELSAKTRIKLQFEKL 1108 HSP 2 Score: 96.2857 bits (238), Expect = 1.294e-19 Identity = 39/84 (46.43%), Postives = 58/84 (69.05%), Query Frame = 1
Query: 94 INEFQIGDSVLYNSKLEGTVRFIGSTASAKGTFYGIELHTADGRTDGTMDGISYFECKEKHGIFARRSQLTKIQSTEVTSSENE 345
+++F+I D VLYN L+GTV FIG+T A G +YG++L + G+ DG++ G SYF+C + HGIF R +QL K+ E T++ E
Sbjct: 1 MSDFKINDIVLYNGTLKGTVEFIGTTHFASGVWYGVKLDSPKGKNDGSVAGKSYFKCDKNHGIFVRNTQLAKVDGDESTNTSAE 84
BLAST of Centrosome-associated protein 350 vs. Planmine SMEST
Match: SMESG000015470.1 (SMESG000015470.1) HSP 1 Score: 75.485 bits (184), Expect = 1.408e-13 Identity = 31/74 (41.89%), Postives = 47/74 (63.51%), Query Frame = 1
Query: 97 NEFQIGDSVLYNSKLEGTVRFIGSTASAKGTFYGIELHTADGRTDGTMDGISYFECKEKHGIFARRSQLTKIQS 318
+ QI D VL + +G +RF+G T + GT+YGIEL G+ DG ++G+ YF+C G+FA S+L K++S
Sbjct: 238 SPLQICDRVLVAGQRKGVIRFVGPTKFSPGTWYGIELDKPVGKNDGAVNGVRYFQCGANRGVFAPLSRLHKLRS 311 HSP 2 Score: 62.7734 bits (151), Expect = 1.079e-9 Identity = 24/70 (34.29%), Postives = 45/70 (64.29%), Query Frame = 1
Query: 109 IGDSVLYNSKLE--GTVRFIGSTASAKGTFYGIELHTADGRTDGTMDGISYFECKEKHGIFARRSQLTKI 312
+GD VL ++ G +R+ G A G + G+EL G+ GT++G+ YF+C+E++G+FA ++++K+
Sbjct: 124 LGDRVLVRGDVDRSGILRYCGPVEFADGVWAGVELDEPQGKNSGTVNGVWYFQCEEQYGVFAPVTRVSKV 193
BLAST of Centrosome-associated protein 350 vs. Planmine SMEST
Match: SMESG000015470.1 (SMESG000015470.1) HSP 1 Score: 75.0998 bits (183), Expect = 2.047e-13 Identity = 31/74 (41.89%), Postives = 47/74 (63.51%), Query Frame = 1
Query: 97 NEFQIGDSVLYNSKLEGTVRFIGSTASAKGTFYGIELHTADGRTDGTMDGISYFECKEKHGIFARRSQLTKIQS 318
+ QI D VL + +G +RF+G T + GT+YGIEL G+ DG ++G+ YF+C G+FA S+L K++S
Sbjct: 304 SPLQICDRVLVAGQRKGVIRFVGPTKFSPGTWYGIELDKPVGKNDGAVNGVRYFQCGANRGVFAPLSRLHKLRS 377 HSP 2 Score: 62.7734 bits (151), Expect = 1.431e-9 Identity = 24/70 (34.29%), Postives = 45/70 (64.29%), Query Frame = 1
Query: 109 IGDSVLYNSKLE--GTVRFIGSTASAKGTFYGIELHTADGRTDGTMDGISYFECKEKHGIFARRSQLTKI 312
+GD VL ++ G +R+ G A G + G+EL G+ GT++G+ YF+C+E++G+FA ++++K+
Sbjct: 190 LGDRVLVRGDVDRSGILRYCGPVEFADGVWAGVELDEPQGKNSGTVNGVWYFQCEEQYGVFAPVTRVSKV 259 The following BLAST results are available for this feature:
BLAST of Centrosome-associated protein 350 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99) Total hits: 5
BLAST of Centrosome-associated protein 350 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99) Total hits: 5
BLAST of Centrosome-associated protein 350 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99) Total hits: 5
BLAST of Centrosome-associated protein 350 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99) Total hits: 5
BLAST of Centrosome-associated protein 350 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99) Total hits: 5
BLAST of Centrosome-associated protein 350 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99) Total hits: 5
BLAST of Centrosome-associated protein 350 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt) Total hits: 5
BLAST of Centrosome-associated protein 350 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL) Total hits: 5
BLAST of Centrosome-associated protein 350 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99) Total hits: 5
BLAST of Centrosome-associated protein 350 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99) Total hits: 5
BLAST of Centrosome-associated protein 350 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46) Total hits: 1
BLAST of Centrosome-associated protein 350 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46) Total hits: 5
BLAST of Centrosome-associated protein 350 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99) Total hits: 5
BLAST of Centrosome-associated protein 350 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST) Total hits: 5
Analyses
This transcript is derived from or has results from the following analyses Sequences
The following sequences are available for this feature:
transcript sequence >SMED30014136 ID=SMED30014136|Name=Centrosome-associated protein 350|organism=Schmidtea mediterranea sexual|type=transcript|length=4055bpback to top protein sequence of SMED30014136-orf-1 >SMED30014136-orf-1 ID=SMED30014136-orf-1|Name=SMED30014136-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=1274bp MINEFQIGDSVLYNSKLEGTVRFIGSTASAKGTFYGIELHTADGRTDGTMback to top Annotated Terms
The following terms have been associated with this transcript:
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
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