SMED30014124

Overview
NameSMED30014124
Smed IDSMED30014124
Length (bp)1050
Neoblast Clusters

Zeng et. al., 2018



▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)



Explore this single cell expression dataset with our NB Cluster Shiny App



 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of SMED30014124 (SMED30014124) t-SNE clustered cells

Violin plots show distribution of expression levels for SMED30014124 (SMED30014124) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of SMED30014124 (SMED30014124) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for SMED30014124 (SMED30014124) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
Sort Descending | Sort Ascending | Only Non-Zero Values | Tile/Chart | Reset

Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020



SMED30014124

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 6

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
nervous systemSMED30014124SMESG000024190.1 dd_Smed_v4_1790_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
neuronSMED30014124SMESG000024190.1 dd_Smed_v4_1790_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		whole organism asexual adult colorimetric in situ hybridization evidence
neoblastSMED30014124SMESG000024190.1 dd_Smed_v4_1790_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
gutSMED30014124SMESG000024190.1 DN313937ncbi_smed_estsPMID:16344473
Zayas et al., 2005		whole organism adult hermaphrodite colorimetric in situ hybridization evidence
central nervous systemSMED30014124SMESG000024190.1 DN313937ncbi_smed_estsPMID:16344473
Zayas et al., 2005		whole organism adult hermaphrodite colorimetric in situ hybridization evidence
testisSMED30014124SMESG000024190.1 DN313937ncbi_smed_estsPMID:16344473
Zayas et al., 2005		whole organism adult hermaphrodite colorimetric in situ hybridization evidence
Note: Hover over icons to view figure legend
Alignments
SMED30014124 aligns in the following genomic locations:
Alignment LocationAlignment Score
v31.001238:34388..41951 +5042
Homology
[Close]
BLAST of SMED30014124 vs. Ensembl Human
Match: TPM3 (tropomyosin 3 [Source:HGNC Symbol;Acc:HGNC:12012])

HSP 1 Score: 92.4337 bits (228), Expect = 4.374e-21
Identity = 71/202 (35.15%), Postives = 121/202 (59.90%), Query Frame = 1 
Query:  178 EQHTRDELDKQVVLLSRKVGVLESDLDDNEKRLQEAKFKLEEITFTAAECERARRQLQSKHDADDERIYHLETLVKEATEQAGEAEARYEEVSRKLIATENVLENTEDEYEKTEKKLREITMEMTSVCNSFRVLEINEARAAEREQKFEVEVKHLKKLLQDADKRANEAENELNQRQMMLDQLEEALDKEKRNHQLLSNDLQ 783
            E+  R++ + +V  L+R++ ++E +LD  ++RL  A  KLEE    A E ER  + ++++   D+E++   E  +KEA   A EA+ +YEEV+RKL+  E  LE TE+  E  E K  E+  E+ +V N+ + LE    + +++E K+E E+K L   L++A+ RA  AE  + + +  +D LEE L  +   ++LLSN+L+
Sbjct:   38 ERRAREQAEAEVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKYEEVARKLVIIEGDLERTEERAELAESKCSELEEELKNVTNNLKSLEAQAEKYSQKEDKYEEEIKILTDKLKEAETRAEFAERSVAKLEKTIDDLEERLYSQLERNRLLSNELK 239
[Close]
BLAST of SMED30014124 vs. Ensembl Human
Match: TPM3 (tropomyosin 3 [Source:HGNC Symbol;Acc:HGNC:12012])

HSP 1 Score: 92.4337 bits (228), Expect = 4.374e-21
Identity = 71/202 (35.15%), Postives = 121/202 (59.90%), Query Frame = 1 
Query:  178 EQHTRDELDKQVVLLSRKVGVLESDLDDNEKRLQEAKFKLEEITFTAAECERARRQLQSKHDADDERIYHLETLVKEATEQAGEAEARYEEVSRKLIATENVLENTEDEYEKTEKKLREITMEMTSVCNSFRVLEINEARAAEREQKFEVEVKHLKKLLQDADKRANEAENELNQRQMMLDQLEEALDKEKRNHQLLSNDLQ 783
            E+  R++ + +V  L+R++ ++E +LD  ++RL  A  KLEE    A E ER  + ++++   D+E++   E  +KEA   A EA+ +YEEV+RKL+  E  LE TE+  E  E K  E+  E+ +V N+ + LE    + +++E K+E E+K L   L++A+ RA  AE  + + +  +D LEE L  +   ++LLSN+L+
Sbjct:   38 ERRAREQAEAEVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKYEEVARKLVIIEGDLERTEERAELAESKCSELEEELKNVTNNLKSLEAQAEKYSQKEDKYEEEIKILTDKLKEAETRAEFAERSVAKLEKTIDDLEERLYSQLERNRLLSNELK 239
[Close]
BLAST of SMED30014124 vs. Ensembl Human
Match: TPM1 (tropomyosin 1 [Source:HGNC Symbol;Acc:HGNC:12010])

HSP 1 Score: 86.2705 bits (212), Expect = 5.846e-19
Identity = 68/214 (31.78%), Postives = 122/214 (57.01%), Query Frame = 1 
Query:  169 LKEEQHTRDELDKQVVLLSRKVGVLESDLDDNEKRLQEAKFKLEEITFTAAECERARRQLQSKHDADDERIYHLETLVKEATEQAGEAEARYEEVSRKLIATENVLENTEDEYEKTEKKLREITMEMTSVCNSFRVLEINEARAAEREQKFEVEVKHLKKLLQDADKRANEAENELNQRQMMLDQLEEALDKEKRNHQLLSNDLQRMVEEFQQM 810
            L  E+  R+  +  V  L+R++ ++E +LD  ++RL  A  KLEE    A E ER  + ++S+   D+E++   E  +KEA   A +A+ +YEEV+RKL+  E+ LE  E+  E +E K  E+  E+ +V N+ + LE    + +++E ++E E+K L   L++A+ RA  AE  + + +  +D LE+ L  +K  ++ +S +L   + +   M
Sbjct:   35 LDHERKLRETAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAEERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDRYEEEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEDELYAQKLKYKAISEELDHALNDMTSM 248
[Close]
BLAST of SMED30014124 vs. Ensembl Human
Match: TPM3 (tropomyosin 3 [Source:HGNC Symbol;Acc:HGNC:12012])

HSP 1 Score: 86.2705 bits (212), Expect = 7.131e-19
Identity = 67/194 (34.54%), Postives = 113/194 (58.25%), Query Frame = 1 
Query:  178 EQHTRDELDKQVVLLSRKVGVLESDLDDNEKRLQEAKFKLEEITFTAAECERARRQLQSKHDADDERIYHLETLVKEATEQAGEAEARYEEVSRKLIATENVLENTEDEYEKTEKKLREITMEMTSVCNSFRVLEINEARAAEREQKFEVEVKHLKKLLQDADKRANEAENELNQRQMMLDQLEEALDKEKRNH 759
            E+  R++ + +V  L+R++ ++E +LD  ++RL  A  KLEE    A E ER  + ++++   D+E++   E  +KEA   A EA+ +YEEV+RKL+  E  LE TE+  E  E K  E+  E+ +V N+ + LE    + +++E K+E E+K L   L++A+ RA  AE  + + +  +D LE+ L   K  H
Sbjct:   38 ERRAREQAEAEVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKYEEVARKLVIIEGDLERTEERAELAESKCSELEEELKNVTNNLKSLEAQAEKYSQKEDKYEEEIKILTDKLKEAETRAEFAERSVAKLEKTIDDLEDKLKCTKEEH 231
[Close]
BLAST of SMED30014124 vs. Ensembl Human
Match: TPM3 (tropomyosin 3 [Source:HGNC Symbol;Acc:HGNC:12012])

HSP 1 Score: 86.2705 bits (212), Expect = 7.586e-19
Identity = 68/202 (33.66%), Postives = 120/202 (59.41%), Query Frame = 1 
Query:  178 EQHTRDELDKQVVLLSRKVGVLESDLDDNEKRLQEAKFKLEEITFTAAECERARRQLQSKHDADDERIYHLETLVKEATEQAGEAEARYEEVSRKLIATENVLENTEDEYEKTEKKLREITMEMTSVCNSFRVLEINEARAAEREQKFEVEVKHLKKLLQDADKRANEAENELNQRQMMLDQLEEALDKEKRNHQLLSNDLQ 783
            E+  R++ + +V  L+R++ ++E +LD  ++RL  A  KLEE    A E ER  + ++++   D+E++   E  +KEA   A EA+ +YEEV+RKL+  E  LE TE+  E  E + RE+  ++  +  + + L   E + +++E K+E E+K L   L++A+ RA  AE  + + +  +D LEE L  +   ++LLSN+L+
Sbjct:   38 ERRAREQAEAEVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKYEEVARKLVIIEGDLERTEERAELAESRCREMDEQIRLMDQNLKCLSAAEEKYSQKEDKYEEEIKILTDKLKEAETRAEFAERSVAKLEKTIDDLEERLYSQLERNRLLSNELK 239
[Close]
BLAST of SMED30014124 vs. Ensembl Celegans
Match: lev-11 (Tropomyosin isoforms a/b/d/f [Source:UniProtKB/Swiss-Prot;Acc:Q22866])

HSP 1 Score: 108.612 bits (270), Expect = 1.789e-27
Identity = 77/212 (36.32%), Postives = 129/212 (60.85%), Query Frame = 1 
Query:  166 KLKEEQHTRDELDKQVVLLSRKVGVLESDLDDNEKRLQEAKFKLEEITFTAAECERARRQLQSKHDADDERIYHLETLVKEATEQAGEAEARYEEVSRKLIATENVLENTEDEYEKTEKKLREITMEMTSVCNSFRVLEINEARAAEREQKFEVEVKHLKKLLQDADKRANEAENELNQRQMMLDQLEEALDKEKRNHQLLSNDLQRMVEEF 801
            +L+EE+  R++ + +V  L+R++ ++E DL+  E RL+ A  KLE+ T  A E +RAR+ ++++   D+ER   LET V EA   A +A+ +YEEV+RKL   E  LE  E+  E  E K+ E+  E+  V N+ + LE++E +A +RE  +E +++ +   L++A+ RA  AE  + + Q  +D+LEE  D E    + L ++L  MV+E 
Sbjct:   42 QLEEERKKREDAEAEVAALNRRIVLVEEDLERTEDRLKTATSKLEQATKAADEADRARKSMETRSQQDEERANFLETQVDEAKVIAEDADRKYEEVARKLAMVEADLERAEERAEAGENKIVELEEELRVVGNNLKSLEVSEEKALQREDSYEEQIRTVSSRLKEAETRAEFAERSVQKLQKEVDRLEELRDAEVLKARQLQDELDHMVQEL 253
[Close]
BLAST of SMED30014124 vs. Ensembl Celegans
Match: lev-11 (Tropomyosin isoforms a/b/d/f [Source:UniProtKB/Swiss-Prot;Acc:Q22866])

HSP 1 Score: 107.071 bits (266), Expect = 7.222e-27
Identity = 75/212 (35.38%), Postives = 129/212 (60.85%), Query Frame = 1 
Query:  166 KLKEEQHTRDELDKQVVLLSRKVGVLESDLDDNEKRLQEAKFKLEEITFTAAECERARRQLQSKHDADDERIYHLETLVKEATEQAGEAEARYEEVSRKLIATENVLENTEDEYEKTEKKLREITMEMTSVCNSFRVLEINEARAAEREQKFEVEVKHLKKLLQDADKRANEAENELNQRQMMLDQLEEALDKEKRNHQLLSNDLQRMVEEF 801
            +L+EE+  R++ + +V  L+R++ ++E DL+  E RL+ A  KLE+ T  A E +RAR+ ++++   D+ER   LET V EA   A +A+ +YEEV+RKL   E  LE  E+  E  E K+ E+  E+  V N+ + LE++E +A +RE  +E +++ +   L++A+ RA  AE  + + Q  +D+LE+ L  EK  ++ +S +L    +E 
Sbjct:   42 QLEEERKKREDAEAEVAALNRRIVLVEEDLERTEDRLKTATSKLEQATKAADEADRARKSMETRSQQDEERANFLETQVDEAKVIAEDADRKYEEVARKLAMVEADLERAEERAEAGENKIVELEEELRVVGNNLKSLEVSEEKALQREDSYEEQIRTVSSRLKEAETRAEFAERSVQKLQKEVDRLEDELVHEKERYKTISEELDSTFQEL 253
[Close]
BLAST of SMED30014124 vs. Ensembl Celegans
Match: lev-11 (Tropomyosin isoforms a/b/d/f [Source:UniProtKB/Swiss-Prot;Acc:Q22866])

HSP 1 Score: 102.064 bits (253), Expect = 4.577e-25
Identity = 75/215 (34.88%), Postives = 126/215 (58.60%), Query Frame = 1 
Query:  166 KLKEEQHTRDELDKQVVLLSRKVGVLESDLDDNEKRLQEAKFKLEEITFTAAECERARRQLQSKHDADDERIYHLETLVKEATEQAGEAEARYEEVSRKLIATENVLENTEDEYEKTEKKLREITMEMTSVCNSFRVLEINEARAAEREQKFEVEVKHLKKLLQDADKRANEAENELNQRQMMLDQLEEALDKEKRNHQLLSNDLQRMVEEFQQM 810
            +L+EE+  R++ + +V  L+R++ ++E DL+  E RL+ A  KLE+ T  A E +R+RR L ++ D DD+R   LE  ++E      E E + EEV+RKL   E  LE  E+  E  E K+ E+  E+  V N+ + LE++E +A +RE  +E +++ +   L++A+ RA  AE  + + Q  +D+LEE  D E    + L ++L  MV+E   +
Sbjct:   42 QLEEERKKREDAEAEVAALNRRIVLVEEDLERTEDRLKTATSKLEQATKAADEADRSRRALSNQIDMDDDRCSDLERKLRECQSILHETENKAEEVARKLAMVEADLERAEERAEAGENKIVELEEELRVVGNNLKSLEVSEEKALQREDSYEEQIRTVSSRLKEAETRAEFAERSVQKLQKEVDRLEELRDAEVLKARQLQDELDHMVQELNSV 256
[Close]
BLAST of SMED30014124 vs. Ensembl Celegans
Match: lev-11 (Tropomyosin isoforms a/b/d/f [Source:UniProtKB/Swiss-Prot;Acc:Q22866])

HSP 1 Score: 100.523 bits (249), Expect = 1.902e-24
Identity = 73/212 (34.43%), Postives = 125/212 (58.96%), Query Frame = 1 
Query:  166 KLKEEQHTRDELDKQVVLLSRKVGVLESDLDDNEKRLQEAKFKLEEITFTAAECERARRQLQSKHDADDERIYHLETLVKEATEQAGEAEARYEEVSRKLIATENVLENTEDEYEKTEKKLREITMEMTSVCNSFRVLEINEARAAEREQKFEVEVKHLKKLLQDADKRANEAENELNQRQMMLDQLEEALDKEKRNHQLLSNDLQRMVEEF 801
            +L+EE+  R++ + +V  L+R++ ++E DL+  E RL+ A  KLE+ T  A E +R+RR L ++ D DD+R   LE  ++E      E E + EEV+RKL   E  LE  E+  E  E K+ E+  E+  V N+ + LE++E +A +RE  +E +++ +   L++A+ RA  AE  + + Q  +D+LE+ L  EK  ++ +S +L    +E 
Sbjct:   42 QLEEERKKREDAEAEVAALNRRIVLVEEDLERTEDRLKTATSKLEQATKAADEADRSRRALSNQIDMDDDRCSDLERKLRECQSILHETENKAEEVARKLAMVEADLERAEERAEAGENKIVELEEELRVVGNNLKSLEVSEEKALQREDSYEEQIRTVSSRLKEAETRAEFAERSVQKLQKEVDRLEDELVHEKERYKTISEELDSTFQEL 253
[Close]
BLAST of SMED30014124 vs. Ensembl Celegans
Match: lev-11 (Tropomyosin isoforms a/b/d/f [Source:UniProtKB/Swiss-Prot;Acc:Q22866])

HSP 1 Score: 97.0561 bits (240), Expect = 3.818e-23
Identity = 66/181 (36.46%), Postives = 112/181 (61.88%), Query Frame = 1 
Query:  166 KLKEEQHTRDELDKQVVLLSRKVGVLESDLDDNEKRLQEAKFKLEEITFTAAECERARRQLQSKHDADDERIYHLETLVKEATEQAGEAEARYEEVSRKLIATENVLENTEDEYEKTEKKLREITMEMTSVCNSFRVLEINEARAAEREQKFEVEVKHLKKLLQDADKRANEAENELNQRQ 708
            +L+EE+  R++ + +V  L+R++ ++E DL+  E RL+ A  KLE+ T  A E +RAR+ ++++   D+ER   LET V EA   A +A+ +YEEV+RKL   E  LE  E+  E  E K+ E+  E+  V N+ + LE++E +A +RE  +E +++ +   L++A+ RA  AE  + + Q
Sbjct:   42 QLEEERKKREDAEAEVAALNRRIVLVEEDLERTEDRLKTATSKLEQATKAADEADRARKSMETRSQQDEERANFLETQVDEAKVIAEDADRKYEEVARKLAMVEADLERAEERAEAGENKIVELEEELRVVGNNLKSLEVSEEKALQREDSYEEQIRTVSSRLKEAETRAEFAERSVQKLQ 222
[Close]
BLAST of SMED30014124 vs. Ensembl Fly
Match: Tm1 (gene:FBgn0003721 transcript:FBtr0089960)

HSP 1 Score: 94.7449 bits (234), Expect = 3.051e-22
Identity = 71/207 (34.30%), Postives = 130/207 (62.80%), Query Frame = 1 
Query:  190 RDELDKQVVLLSRKVGVLESDLDDNEKRLQEAKFKLEEITFTAAECERARRQLQSKHDADDERIYHLETLVKEATEQAGEAEARYEEVSRKLIATENVLENTEDEYEKTEKKLREITMEMTSVCNSFRVLEINEARAAEREQKFEVEVKHLKKLLQDADKRANEAENELNQRQMMLDQLEEALDKEKRNHQLLSNDLQRMVEEFQQM 810
            R+E + +V  L+R++ +LE DL+ +E+RL  A  KL E +  A E ER R+ L+++ + +D+++  LE  + +A   A EA+ +YEEV+RKL+  E  LE +E++ E +E K+ E+  E+  V N+ + LE++E +A ++E+ FE ++K L   L++A+ RA  AE  + + Q  +D+LE+ L   +  ++LL  +++  + + Q M
Sbjct:   46 REEAESEVAALNRRIQLLEEDLERSEERLGSATAKLSEASQAADESERIRKALENRTNMEDDKVALLENQLAQAKLIAEEADKKYEEVARKLVLMEQDLERSEEKVELSESKIVELEEELRVVGNNLKSLEVSEEKATQKEETFETQIKVLDHSLKEAEARAEFAERSVQKLQKEVDRLEDDLLNVRGKNKLLQEEMEATLHDIQNM 252
[Close]
BLAST of SMED30014124 vs. Ensembl Fly
Match: Tm1 (gene:FBgn0003721 transcript:FBtr0305656)

HSP 1 Score: 92.4337 bits (228), Expect = 2.174e-21
Identity = 68/198 (34.34%), Postives = 128/198 (64.65%), Query Frame = 1 
Query:  190 RDELDKQVVLLSRKVGVLESDLDDNEKRLQEAKFKLEEITFTAAECERARRQLQSKHDADDERIYHLETLVKEATEQAGEAEARYEEVSRKLIATENVLENTEDEYEKTEKKLREITMEMTSVCNSFRVLEINEARAAEREQKFEVEVKHLKKLLQDADKRANEAENELNQRQMMLDQLEEALDKEKRNHQLLSNDLQ 783
            R+E + +V  L+R++ +LE DL+ +E+RL  A  KL E +  A E ER R+ L+++ + +D+++  LE  + +A   A EA+ +YEEV+RKL+  E  LE +E++ E +E K+ E+  E+  V N+ + LE++E +A +RE++++ ++K L   L++A+ RA  AE  + + Q  +D+LE+ + K K  ++ ++ +L+
Sbjct:   46 REEAESEVAALNRRIQLLEEDLERSEERLGSATAKLSEASQAADESERIRKALENRTNMEDDKVALLENQLAQAKLIAEEADKKYEEVARKLVLMEQDLERSEEKVELSESKIVELEEELRVVGNNLKSLEVSEEKANQREEEYKNQIKTLNTRLKEAEARAEFAERSVQKLQKEVDRLEDEVSKGKEKYKTIAQELE 243
[Close]
BLAST of SMED30014124 vs. Ensembl Fly
Match: Tm1 (gene:FBgn0003721 transcript:FBtr0305654)

HSP 1 Score: 92.8189 bits (229), Expect = 2.747e-21
Identity = 76/205 (37.07%), Postives = 128/205 (62.44%), Query Frame = 1 
Query:  166 KLKEEQHTRDELDKQVVLLSRKVGVLESDLDDNEKRLQEAKFKLEEITFTAAECERARRQLQSKHDADDERIYHLETLVKEATEQAGEAEARYEEVSRKLIATENVLENTEDEYEKTEKKLREITMEMTSVCNSFRVLEINEARAAEREQKFEVEVKHLKKLLQDADKRANEAENELNQRQMMLDQLEEALDKEKRNHQLLSNDL 780
            KL+E+       + +V  L+R++ +LE DL+ +E+RL  A  KL E +  A E ERAR+ L+++  AD+ER+  LE  +KEA   A EA+ +Y+EV+RKL   E  LE  E+  E+ E K+ E+  E+  V N+ + LE++E +A +RE++++ ++K L   L++A+ RA  AE  + + Q  +D+LE+ L  EK  ++ + +DL
Sbjct:   70 KLEEKNKALQNAESEVAALNRRIQLLEEDLERSEERLGSATAKLSEASQAADESERARKILENRALADEERMDALENQLKEARFLAEEADKKYDEVARKLAMVEADLERAEERAEQGENKIVELEEELRVVGNNLKSLEVSEEKANQREEEYKNQIKTLNTRLKEAEARAEFAERSVQKLQKEVDRLEDDLVLEKERYKDIGDDL 274
[Close]
BLAST of SMED30014124 vs. Ensembl Fly
Match: Tm1 (gene:FBgn0003721 transcript:FBtr0089964)

HSP 1 Score: 92.8189 bits (229), Expect = 2.747e-21
Identity = 76/205 (37.07%), Postives = 128/205 (62.44%), Query Frame = 1 
Query:  166 KLKEEQHTRDELDKQVVLLSRKVGVLESDLDDNEKRLQEAKFKLEEITFTAAECERARRQLQSKHDADDERIYHLETLVKEATEQAGEAEARYEEVSRKLIATENVLENTEDEYEKTEKKLREITMEMTSVCNSFRVLEINEARAAEREQKFEVEVKHLKKLLQDADKRANEAENELNQRQMMLDQLEEALDKEKRNHQLLSNDL 780
            KL+E+       + +V  L+R++ +LE DL+ +E+RL  A  KL E +  A E ERAR+ L+++  AD+ER+  LE  +KEA   A EA+ +Y+EV+RKL   E  LE  E+  E+ E K+ E+  E+  V N+ + LE++E +A +RE++++ ++K L   L++A+ RA  AE  + + Q  +D+LE+ L  EK  ++ + +DL
Sbjct:   70 KLEEKNKALQNAESEVAALNRRIQLLEEDLERSEERLGSATAKLSEASQAADESERARKILENRALADEERMDALENQLKEARFLAEEADKKYDEVARKLAMVEADLERAEERAEQGENKIVELEEELRVVGNNLKSLEVSEEKANQREEEYKNQIKTLNTRLKEAEARAEFAERSVQKLQKEVDRLEDDLVLEKERYKDIGDDL 274
[Close]
BLAST of SMED30014124 vs. Ensembl Fly
Match: Tm1 (gene:FBgn0003721 transcript:FBtr0089967)

HSP 1 Score: 92.8189 bits (229), Expect = 2.747e-21
Identity = 76/205 (37.07%), Postives = 128/205 (62.44%), Query Frame = 1 
Query:  166 KLKEEQHTRDELDKQVVLLSRKVGVLESDLDDNEKRLQEAKFKLEEITFTAAECERARRQLQSKHDADDERIYHLETLVKEATEQAGEAEARYEEVSRKLIATENVLENTEDEYEKTEKKLREITMEMTSVCNSFRVLEINEARAAEREQKFEVEVKHLKKLLQDADKRANEAENELNQRQMMLDQLEEALDKEKRNHQLLSNDL 780
            KL+E+       + +V  L+R++ +LE DL+ +E+RL  A  KL E +  A E ERAR+ L+++  AD+ER+  LE  +KEA   A EA+ +Y+EV+RKL   E  LE  E+  E+ E K+ E+  E+  V N+ + LE++E +A +RE++++ ++K L   L++A+ RA  AE  + + Q  +D+LE+ L  EK  ++ + +DL
Sbjct:   70 KLEEKNKALQNAESEVAALNRRIQLLEEDLERSEERLGSATAKLSEASQAADESERARKILENRALADEERMDALENQLKEARFLAEEADKKYDEVARKLAMVEADLERAEERAEQGENKIVELEEELRVVGNNLKSLEVSEEKANQREEEYKNQIKTLNTRLKEAEARAEFAERSVQKLQKEVDRLEDDLVLEKERYKDIGDDL 274
[Close]
BLAST of SMED30014124 vs. Ensembl Zebrafish
Match: tpm1 (tropomyosin 1 (alpha) [Source:ZFIN;Acc:ZDB-GENE-040426-854])

HSP 1 Score: 88.5817 bits (218), Expect = 5.560e-20
Identity = 70/214 (32.71%), Postives = 121/214 (56.54%), Query Frame = 1 
Query:  169 LKEEQHTRDELDKQVVLLSRKVGVLESDLDDNEKRLQEAKFKLEEITFTAAECERARRQLQSKHDADDERIYHLETLVKEATEQAGEAEARYEEVSRKLIATENVLENTEDEYEKTEKKLREITMEMTSVCNSFRVLEINEARAAEREQKFEVEVKHLKKLLQDADKRANEAENELNQRQMMLDQLEEALDKEKRNHQLLSNDLQRMVEEFQQM 810
            L  E+  R+  +  V  L+R++ ++E +LD  ++RL  A  KLEE    A E ER  + ++++   D+E++   E  +KEA   A EA+ +YEEV+RKL+  E  LE TE+  E  E K  E+  E+ +V N+ + LE    + +++E K+E E+K L   L++A+ RA  AE  + + +  +D LE+ L  +K  ++ +S +L   + +   M
Sbjct:   34 LAHERKARETAEGDVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIENRALKDEEKMEIQEIQLKEAKHIAEEADRKYEEVARKLVIVEGELERTEERAELNESKCSELEEELKTVTNNLKSLEAQAEKYSQKEDKYEEEIKVLTDKLKEAETRAEFAERSVAKLEKTIDDLEDELYSQKLKYKAISEELDHALNDMTSM 247
[Close]
BLAST of SMED30014124 vs. Ensembl Zebrafish
Match: tpm3 (tropomyosin 3 [Source:ZFIN;Acc:ZDB-GENE-030826-16])

HSP 1 Score: 87.8113 bits (216), Expect = 1.196e-19
Identity = 67/191 (35.08%), Postives = 115/191 (60.21%), Query Frame = 1 
Query:  166 KLKEEQHTRDELDKQVVLLSRKVGVLESDLDDNEKRLQEAKFKLEEITFTAAECERARRQLQSKHDADDERIYHLETLVKEATEQAGEAEARYEEVSRKLIATENVLENTEDEYEKTEKKLREITMEMTSVCNSFRVLEINEARAAEREQKFEVEVKHLKKLLQDADKRANEAENELNQRQMMLDQLEEAL 738
            +++EE+  R++ + +V  L+R++ ++E +LD  ++RL  A  KLEE    A E ER  + ++++   D+E++   E  +KEA   A EA+ +YEEV+RKL+  E  LE TE+  E  E K  E+  E+ +V N+ + LE    + +++E K+E E+K L   L++A+ RA  AE  + + +  +D LEE L
Sbjct:   34 QVEEEKRAREQAEAEVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKYEEVARKLVIVEGELERTEERAELAESKCAELEEELKNVTNNLKSLEAQAEKYSQKEDKYEEEIKILTDKLKEAETRAEFAERSVAKLEKTIDDLEEKL 224
[Close]
BLAST of SMED30014124 vs. Ensembl Zebrafish
Match: tpm1 (tropomyosin 1 (alpha) [Source:ZFIN;Acc:ZDB-GENE-040426-854])

HSP 1 Score: 87.4261 bits (215), Expect = 1.767e-19
Identity = 69/204 (33.82%), Postives = 118/204 (57.84%), Query Frame = 1 
Query:  169 LKEEQHTRDELDKQVVLLSRKVGVLESDLDDNEKRLQEAKFKLEEITFTAAECERARRQLQSKHDADDERIYHLETLVKEATEQAGEAEARYEEVSRKLIATENVLENTEDEYEKTEKKLREITMEMTSVCNSFRVLEINEARAAEREQKFEVEVKHLKKLLQDADKRANEAENELNQRQMMLDQLEEALDKEKRNHQLLSNDL 780
            L  E+  R+  +  V  L+R++ ++E +LD  ++RL  A  KLEE    A E ER  + ++++   D+E++   E  +KEA   A EA+ +YEEV+RKL+  E  LE TE+  E  E K  E+  E+ +V N+ + LE    + +++E K+E E+K L   L++A+ RA  AE  + + +  +D LE+ L  +K  ++ +S +L
Sbjct:   34 LAHERKARETAEGDVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIENRALKDEEKMEIQEIQLKEAKHIAEEADRKYEEVARKLVIVEGELERTEERAELNESKCSELEEELKTVTNNLKSLEAQAEKYSQKEDKYEEEIKVLTDKLKEAETRAEFAERSVAKLEKTIDDLEDELYSQKLKYKAISEEL 237
[Close]
BLAST of SMED30014124 vs. Ensembl Zebrafish
Match: tpm1 (tropomyosin 1 (alpha) [Source:ZFIN;Acc:ZDB-GENE-040426-854])

HSP 1 Score: 87.4261 bits (215), Expect = 3.282e-19
Identity = 72/212 (33.96%), Postives = 121/212 (57.08%), Query Frame = 1 
Query:  175 EEQHTRDELDKQVVLLSRKVGVLESDLDDNEKRLQEAKFKLEEITFTAAECERARRQLQSKHDADDERIYHLETLVKEATEQAGEAEARYEEVSRKLIATENVLENTEDEYEKTEKKLREITMEMTSVCNSFRVLEINEARAAEREQKFEVEVKHLKKLLQDADKRANEAENELNQRQMMLDQLEEALDKEKRNHQLLSNDLQRMVEEFQQM 810
            EE  T+ E D  V  L+R++ ++E +LD  ++RL  A  KLEE    A E ER  + ++++   D+E++   E  +KEA   A EA+ +YEEV+RKL+  E  LE TE+  E  E K  E+  E+ +V N+ + LE    + +++E K+E E+K L   L++A+ RA  AE  + + +  +D LE+ L  +K  ++ +S +L   + +   M
Sbjct:   75 EEVATKAEGD--VASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIENRALKDEEKMEIQEIQLKEAKHIAEEADRKYEEVARKLVIVEGELERTEERAELNESKCSELEEELKTVTNNLKSLEAQAEKYSQKEDKYEEEIKVLTDKLKEAETRAEFAERSVAKLEKTIDDLEDELYSQKLKYKAISEELDHALNDMTSM 284
[Close]
BLAST of SMED30014124 vs. Ensembl Zebrafish
Match: tpm1 (tropomyosin 1 (alpha) [Source:ZFIN;Acc:ZDB-GENE-040426-854])

HSP 1 Score: 86.6557 bits (213), Expect = 4.961e-19
Identity = 67/200 (33.50%), Postives = 115/200 (57.50%), Query Frame = 1 
Query:  211 VVLLSRKVGVLESDLDDNEKRLQEAKFKLEEITFTAAECERARRQLQSKHDADDERIYHLETLVKEATEQAGEAEARYEEVSRKLIATENVLENTEDEYEKTEKKLREITMEMTSVCNSFRVLEINEARAAEREQKFEVEVKHLKKLLQDADKRANEAENELNQRQMMLDQLEEALDKEKRNHQLLSNDLQRMVEEFQQM 810
            V  L+R++ ++E +LD  ++RL  A  KLEE    A E ER  + ++++   D+E++   E  +KEA   A EA+ +YEEV+RKL+  E  LE TE+  E  E K  E+  E+ +V N+ + LE    + +++E K+E E+K L   L++A+ RA  AE  + + +  +D LE+ L  +K  ++ +S +L   + +   M
Sbjct:   85 VASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIENRALKDEEKMEIQEIQLKEAKHIAEEADRKYEEVARKLVIVEGELERTEERAELNESKCSELEEELKTVTNNLKSLEAQAEKYSQKEDKYEEEIKVLTDKLKEAETRAEFAERSVAKLEKTIDDLEDELYSQKLKYKAISEELDHALNDMTSM 284
[Close]
BLAST of SMED30014124 vs. Ensembl Xenopus
Match: tpm1 (tropomyosin 1 [Source:NCBI gene;Acc:448541])

HSP 1 Score: 84.7297 bits (208), Expect = 5.174e-18
Identity = 66/200 (33.00%), Postives = 115/200 (57.50%), Query Frame = 1 
Query:  211 VVLLSRKVGVLESDLDDNEKRLQEAKFKLEEITFTAAECERARRQLQSKHDADDERIYHLETLVKEATEQAGEAEARYEEVSRKLIATENVLENTEDEYEKTEKKLREITMEMTSVCNSFRVLEINEARAAEREQKFEVEVKHLKKLLQDADKRANEAENELNQRQMMLDQLEEALDKEKRNHQLLSNDLQRMVEEFQQM 810
            V  L+R++ ++E +LD  ++RL  A  KLEE    A E ER  + ++++   D+E++   E  +KEA   A EA+ +YEEV+RKL+  E  LE  E+  E +E K  E+  E+ +V N+ + LE    + +++E K+E E+K L   L++A+ RA  AE  + + +  +D LE+ L  +K  ++ +S +L   + +   M
Sbjct:   97 VASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKYEEVARKLVIIEGDLERAEERAELSESKCAELEEELKTVTNNLKSLEAQAEKYSQKEDKYEEEIKVLTDKLKEAETRAEFAERTVAKLEKTIDDLEDELYAQKLKYKAISEELDHALNDMTSM 296
[Close]
BLAST of SMED30014124 vs. Ensembl Xenopus
Match: tpm1 (tropomyosin 1 [Source:NCBI gene;Acc:448541])

HSP 1 Score: 83.1889 bits (204), Expect = 1.143e-17
Identity = 65/190 (34.21%), Postives = 112/190 (58.95%), Query Frame = 1 
Query:  211 VVLLSRKVGVLESDLDDNEKRLQEAKFKLEEITFTAAECERARRQLQSKHDADDERIYHLETLVKEATEQAGEAEARYEEVSRKLIATENVLENTEDEYEKTEKKLREITMEMTSVCNSFRVLEINEARAAEREQKFEVEVKHLKKLLQDADKRANEAENELNQRQMMLDQLEEALDKEKRNHQLLSNDL 780
            V  L+R++ ++E +LD  ++RL  A  KLEE    A E ER  + ++++   D+E++   E  +KEA   A EA+ +YEEV+RKL+  E  LE  E+  E +E K  E+  E+ +V N+ + LE    + +++E K+E E+K L   L++A+ RA  AE  + + +  +D LE+ L  +K  ++ +S +L
Sbjct:   85 VASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKYEEVARKLVIIEGDLERAEERAELSESKCAELEEELKTVTNNLKSLEAQAEKYSQKEDKYEEEIKVLTDKLKEAETRAEFAERTVAKLEKTIDDLEDELYAQKLKYKAISEEL 274
[Close]
BLAST of SMED30014124 vs. Ensembl Xenopus
Match: tpm1 (tropomyosin 1 [Source:NCBI gene;Acc:448541])

HSP 1 Score: 82.0333 bits (201), Expect = 6.695e-17
Identity = 67/194 (34.54%), Postives = 110/194 (56.70%), Query Frame = 1 
Query:  211 VVLLSRKVGVLESDLDDNEKRLQEAKFKLEEITFTAAECERARRQLQSKHDADDERIYHLETLVKEATEQAGEAEARYEEVSRKLIATENVLENTEDEYEKTEKKLREITMEMTSVCNSFRVLEINEARAAEREQKFEVEVKHLKKLLQDADKRANEAENELNQRQMMLDQLEEALDKEKRN----HQLLSNDL 780
            V  L+R++ ++E +LD  ++RL  A  KLEE    A E ER  + ++++   D+E++   E  +KEA   A EA+ +YEEV+RKL+  E  LE  E+  E +E K  E+  E+ +V N+ + LE    + +++E K+E E+K L   L++A+ RA  AE  + + +  +D LEE +   K      HQ+L   L
Sbjct:  134 VASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKYEEVARKLVIIEGDLERAEERAELSESKCAELEEELKTVTNNLKSLEAQAEKYSQKEDKYEEEIKVLTDKLKEAETRAEFAERTVAKLEKTIDDLEEKVTHAKEENLNMHQMLDQTL 327
[Close]
BLAST of SMED30014124 vs. Ensembl Xenopus
Match: gucy2d (guanylate cyclase 2D, membrane (retina-specific) [Source:Xenbase;Acc:XB-GENE-1014102])

HSP 1 Score: 80.1073 bits (196), Expect = 8.073e-17
Identity = 72/211 (34.12%), Postives = 120/211 (56.87%), Query Frame = 1 
Query:  169 LKEEQHTRDELDKQVVLLSRKVGVLESDLDDNEKRLQEAKFKLEEITFTAAECERARRQLQSKHDADDERIYHLETLVKEATEQAGEAEARYEEVSRKLIATENVLENTEDEYEKTEKKLREITMEMTSVCNSFRVLEINEARAAEREQKFEVEVKHLKKLLQDADKRANEAENELNQRQMMLDQLEEALDKEKRN----HQLLSNDLQRM 789
            L  E+  RD+ + +V  L+R++ ++E +LD  ++RL  A  KLEE    A E ER  + ++++   D+E++   E  +KEA   A EA+ +YEEV+RKL+  E  LE  E+  E +E K  ++  E+ +V N+ + LE    + +E+E K+E E+K L   L++A+ RA  AE  + + +  +D LE+ L   K      HQ+L   LQ +
Sbjct:   35 LDSEREMRDKAEGEVAALNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIENRAMKDEEKMEIQELQLKEAKHIAEEADRKYEEVARKLVILEGELERAEERAEVSELKCSDLEEELKNVTNNLKSLEAQSEKYSEKEDKYEEEIKILTDKLKEAETRAEFAERSVAKLEKTIDDLEDKLATAKEENLGMHQVLDQTLQEL 245
[Close]
BLAST of SMED30014124 vs. Ensembl Xenopus
Match: tpm1 (tropomyosin 1 [Source:NCBI gene;Acc:448541])

HSP 1 Score: 78.5666 bits (192), Expect = 5.684e-16
Identity = 61/173 (35.26%), Postives = 102/173 (58.96%), Query Frame = 1 
Query:  211 VVLLSRKVGVLESDLDDNEKRLQEAKFKLEEITFTAAECERARRQLQSKHDADDERIYHLETLVKEATEQAGEAEARYEEVSRKLIATENVLENTEDEYEKTEKKLREITMEMTSVCNSFRVLEINEARAAEREQKFEVEVKHLKKLLQDADKRANEAENELNQRQMMLDQLE 729
            V  L+R++ ++E +LD  ++RL  A  KLEE    A E ER  + ++++   D+E++   E  +KEA   A EA+ +YEEV+RKL+  E  LE  E+  E +E K  E+  E+ +V N+ + LE    + +++E K+E E+K L   L++A+ RA  AE  + + +  +D LE
Sbjct:   85 VASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKYEEVARKLVIIEGDLERAEERAELSESKCAELEEELKTVTNNLKSLEAQAEKYSQKEDKYEEEIKVLTDKLKEAETRAEFAERTVAKLEKTIDDLE 257
[Close]
BLAST of SMED30014124 vs. Ensembl Mouse
Match: Tpm3 (tropomyosin 3, gamma [Source:MGI Symbol;Acc:MGI:1890149])

HSP 1 Score: 92.4337 bits (228), Expect = 2.688e-21
Identity = 71/202 (35.15%), Postives = 121/202 (59.90%), Query Frame = 1 
Query:  178 EQHTRDELDKQVVLLSRKVGVLESDLDDNEKRLQEAKFKLEEITFTAAECERARRQLQSKHDADDERIYHLETLVKEATEQAGEAEARYEEVSRKLIATENVLENTEDEYEKTEKKLREITMEMTSVCNSFRVLEINEARAAEREQKFEVEVKHLKKLLQDADKRANEAENELNQRQMMLDQLEEALDKEKRNHQLLSNDLQ 783
            E+  R++ + +V  L+R++ ++E +LD  ++RL  A  KLEE    A E ER  + ++++   D+E++   E  +KEA   A EA+ +YEEV+RKL+  E  LE TE+  E  E K  E+  E+ +V N+ + LE    + +++E K+E E+K L   L++A+ RA  AE  + + +  +D LEE L  +   ++LLSN+L+
Sbjct:   38 ERRAREQAEAEVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKYEEVARKLVIIEGDLERTEERAELAESKCSELEEELKNVTNNLKSLEAQAEKYSQKEDKYEEEIKILTDKLKEAETRAEFAERSVAKLEKTIDDLEERLYSQLERNRLLSNELK 239
[Close]
BLAST of SMED30014124 vs. Ensembl Mouse
Match: Tpm3 (tropomyosin 3, gamma [Source:MGI Symbol;Acc:MGI:1890149])

HSP 1 Score: 88.9669 bits (219), Expect = 5.106e-20
Identity = 68/201 (33.83%), Postives = 120/201 (59.70%), Query Frame = 1 
Query:  178 EQHTRDELDKQVVLLSRKVGVLESDLDDNEKRLQEAKFKLEEITFTAAECERARRQLQSKHDADDERIYHLETLVKEATEQAGEAEARYEEVSRKLIATENVLENTEDEYEKTEKKLREITMEMTSVCNSFRVLEINEARAAEREQKFEVEVKHLKKLLQDADKRANEAENELNQRQMMLDQLEEALDKEKRNHQLLSNDL 780
            E+  R++ + +V  L+R++ ++E +LD  ++RL  A  KLEE    A E ER  + ++++   D+E++   E  +KEA   A EA+ +YEEV+RKL+  E  LE TE+  E  E K  E+  E+ +V N+ + LE    + +++E K+E E+K L   L++A+ RA  AE  + + +  +D LE+ L  +K  ++ +S++L
Sbjct:   38 ERRAREQAEAEVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKYEEVARKLVIIEGDLERTEERAELAESKCSELEEELKNVTNNLKSLEAQAEKYSQKEDKYEEEIKILTDKLKEAETRAEFAERSVAKLEKTIDDLEDELYAQKLKYKAISDEL 238
[Close]
BLAST of SMED30014124 vs. Ensembl Mouse
Match: Tpm1 (tropomyosin 1, alpha [Source:MGI Symbol;Acc:MGI:98809])

HSP 1 Score: 87.0409 bits (214), Expect = 4.146e-19
Identity = 71/214 (33.18%), Postives = 123/214 (57.48%), Query Frame = 1 
Query:  169 LKEEQHTRDELDKQVVLLSRKVGVLESDLDDNEKRLQEAKFKLEEITFTAAECERARRQLQSKHDADDERIYHLETLVKEATEQAGEAEARYEEVSRKLIATENVLENTEDEYEKTEKKLREITMEMTSVCNSFRVLEINEARAAEREQKFEVEVKHLKKLLQDADKRANEAENELNQRQMMLDQLEEALDKEKRNHQLLSNDLQRMVEEFQQM 810
            L E++ T  E D  V  L+R++ ++E +LD  ++RL  A  KLEE    A E ER  + ++S+   D+E++   E  +KEA   A +A+ +YEEV+RKL+  E+ LE  E+  E +E K  E+  E+ +V N+ + LE    + +++E K+E E+K L   L++A+ RA  AE  + + +  +D LE+ L  +K  ++ +S +L   + +   M
Sbjct:   73 LAEKKATDAEAD--VASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAEERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDKYEEEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEDELYAQKLKYKAISEELDHALNDMTSM 284
[Close]
BLAST of SMED30014124 vs. Ensembl Mouse
Match: Tpm1 (tropomyosin 1, alpha [Source:MGI Symbol;Acc:MGI:98809])

HSP 1 Score: 85.8853 bits (211), Expect = 5.551e-19
Identity = 68/205 (33.17%), Postives = 121/205 (59.02%), Query Frame = 1 
Query:  169 LKEEQHTRDELDKQVVLLSRKVGVLESDLDDNEKRLQEAKFKLEEITFTAAECERARRQLQSKHDADDERIYHLETLVKEATEQAGEAEARYEEVSRKLIATENVLENTEDEYEKTEKKLREITMEMTSVCNSFRVLEINEARAAEREQKFEVEVKHLKKLLQDADKRANEAENELNQRQMMLDQLEEALDKEKRNHQLLSNDLQ 783
            L +E+  R+  +  V  L+R++ ++E +LD  ++RL  A  KLEE    A E ER  + ++S+   D+E++   E  +KEA   A +A+ +YEEV+RKL+  E+ LE  E+  E +E K  E+  E+ +V N+ + LE    + +++E K+E E+K L   L++A+ RA  AE  + + +  +D LE+ L  +   ++ L+N+L+
Sbjct:   35 LDQERKLRETAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAEERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDKYEEEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEDQLYHQLEQNRRLTNELK 239
[Close]
BLAST of SMED30014124 vs. Ensembl Mouse
Match: Tpm3 (tropomyosin 3, gamma [Source:MGI Symbol;Acc:MGI:1890149])

HSP 1 Score: 86.2705 bits (212), Expect = 8.333e-19
Identity = 66/190 (34.74%), Postives = 113/190 (59.47%), Query Frame = 1 
Query:  211 VVLLSRKVGVLESDLDDNEKRLQEAKFKLEEITFTAAECERARRQLQSKHDADDERIYHLETLVKEATEQAGEAEARYEEVSRKLIATENVLENTEDEYEKTEKKLREITMEMTSVCNSFRVLEINEARAAEREQKFEVEVKHLKKLLQDADKRANEAENELNQRQMMLDQLEEALDKEKRNHQLLSNDL 780
            V  L+R++ ++E +LD  ++RL  A  KLEE    A E ER  + ++++   D+E++   E  +KEA   A EA+ +YEEV+RKL+  E  LE TE+  E  E K  E+  E+ +V N+ + LE    + +++E K+E E+K L   L++A+ RA  AE  + + +  +D LE+ L  +K  ++ +S++L
Sbjct:   85 VASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKYEEVARKLVIIEGDLERTEERAELAESKCSELEEELKNVTNNLKSLEAQAEKYSQKEDKYEEEIKILTDKLKEAETRAEFAERSVAKLEKTIDDLEDELYAQKLKYKAISDEL 274
[Close]
BLAST of SMED30014124 vs. UniProt/SwissProt
Match: sp|P42638|TPM2_SCHMA (Tropomyosin-2 OS=Schistosoma mansoni OX=6183 PE=2 SV=1)

HSP 1 Score: 114.39 bits (285), Expect = 3.250e-28
Identity = 84/212 (39.62%), Postives = 127/212 (59.91%), Query Frame = 1 
Query:  145 QLHEKETKLKEEQHTRDELDKQVVLLSRKVGVLESDLDDNEKRLQEAKFKLEEITFTAAECERARRQLQSKHDADDERIYHLETLVKEATEQAGEAEARYEEVSRKLIATENVLENTEDEYEKTEKKLREITMEMTSVCNSFRVLEINEARAAEREQKFEVEVKHLKKLLQDADKRANEAENELNQRQMMLDQLEEALDKEKRNHQLLSNDL 780
            QL E  TKL+E      E + +V  L +++  LE +L+  E RLQEA  KLEE +  A E +R R+ L+++  AD+ERI  LE  +KE+T  A +A+ +Y+E +RKL  TE  LE  E   E  E K+ E+  E+  V N+ + LEI+E  AA+RE+ +E  ++ L + L+ A+ RA E+E  +N  Q   D+LE+ L  EK  ++ LS +L
Sbjct:   63 QLAETNTKLEETDKRATEAEAEVASLQKRIRQLEDELESTETRLQEATVKLEEASKAADESDRGRKVLENRTFADEERINQLEEQLKESTFMAEDADRKYDEAARKLAITEVELERAESRLEAAESKITELEEELRIVGNNVKSLEISEQEAAQREEAYEENIRDLTERLKAAEDRAQESERLVNTLQADADRLEDELVTEKEKYKALSEEL 274
[Close]
BLAST of SMED30014124 vs. UniProt/SwissProt
Match: sp|Q25145|TPM_HALRU (Tropomyosin OS=Haliotis rufescens OX=6454 PE=2 SV=1)

HSP 1 Score: 114.005 bits (284), Expect = 4.517e-28
Identity = 80/202 (39.60%), Postives = 125/202 (61.88%), Query Frame = 1 
Query:  196 ELDKQVVLLSRKVGVLESDLDDNEKRLQEAKFKLEEITFTAAECERARRQLQSKHDADDERIYHLETLVKEATEQAGEAEARYEEVSRKLIATENVLENTEDEYEKTEKKLREITMEMTSVCNSFRVLEINEARAAEREQKFEVEVKHLKKLLQDADKRANEAENELNQRQMMLDQLEEALDKEKRNHQLLSNDLQRMVEEF 801
            E++++V   +RK+ +LE DL+ NE+RLQ A  +LEE +    E ER  R L+S+  ADDERI  LE  +KEA   A +AE +Y+E +RKL  TE  LE  E   +  E K+ E+  E+  V N+ + LEI+E  A++RE  +E  ++ L + L+DA+ RA EAE  +++ Q  +D+LE+ L  EK  ++ +S++L +   E 
Sbjct:   80 EMEQEVSGTTRKITLLEEDLERNEERLQTATERLEEASKLPDESERGARVLESRSLADDERIDQLEAQLKEAKYIAEDAERKYDEAARKLAITEVDLERAEARPKAAEAKILELEEELKVVGNNTKSLEISEQEASQREDSYEETIRDLTQRLKDAENRATEAERTVSKLQKEVDRLEDELLAEKEKYKAISDELDQTFAEL 281
[Close]
BLAST of SMED30014124 vs. UniProt/SwissProt
Match: sp|Q9GZ71|TPM_HALDV (Tropomyosin OS=Haliotis diversicolor OX=36095 PE=1 SV=1)

HSP 1 Score: 112.079 bits (279), Expect = 2.509e-27
Identity = 87/219 (39.73%), Postives = 133/219 (60.73%), Query Frame = 1 
Query:  145 QLHEKETKLKEEQHTRDELDKQVVLLSRKVGVLESDLDDNEKRLQEAKFKLEEITFTAAECERARRQLQSKHDADDERIYHLETLVKEATEQAGEAEARYEEVSRKLIATENVLENTEDEYEKTEKKLREITMEMTSVCNSFRVLEINEARAAEREQKFEVEVKHLKKLLQDADKRANEAENELNQRQMMLDQLEEALDKEKRNHQLLSNDLQRMVEEF 801
            QL E   KL+  +    E++++V   +RK+ +LE DL+ NE+RLQ A  +LEE +  A E ER  R L+S+  ADDERI  LE  +KEA   A +AE +Y+E +RKL  TE  LE  E   E  E K+ E+  E+  V N+ + LEI+E  A++RE  +E  ++ L + L+DA+ RA EAE  +++ Q  +D+LE+ L  EK  ++ +S++L +   E 
Sbjct:   63 QLQEAMAKLETSEKRVTEMEQEVSGTTRKITLLEEDLERNEERLQTATERLEEASKAADESERGARVLESRSLADDERIDQLEAQLKEAKYIAEDAERKYDEAARKLAITEVDLERAEARLEAAEAKILELEEELKVVGNNMKSLEISEQEASQREDSYEETIRDLTQRLKDAENRATEAERTVSKLQKEVDRLEDELLAEKEKYKAISDELDQTFAEL 281
[Close]
BLAST of SMED30014124 vs. UniProt/SwissProt
Match: sp|P43689|TPM2_BIOGL (Tropomyosin-2 OS=Biomphalaria glabrata OX=6526 PE=2 SV=1)

HSP 1 Score: 109.383 bits (272), Expect = 2.089e-26
Identity = 86/218 (39.45%), Postives = 132/218 (60.55%), Query Frame = 1 
Query:  148 LHEKETKLKEEQHTRDELDKQVVLLSRKVGVLESDLDDNEKRLQEAKFKLEEITFTAAECERARRQLQSKHDADDERIYHLETLVKEATEQAGEAEARYEEVSRKLIATENVLENTEDEYEKTEKKLREITMEMTSVCNSFRVLEINEARAAEREQKFEVEVKHLKKLLQDADKRANEAENELNQRQMMLDQLEEALDKEKRNHQLLSNDLQRMVEEF 801
            L E +TKL+  +    EL+     L+R++ +LE DL+ +E+RLQ A  KLEE +  A E ER R+ L+S+  ADDER+  LE  +KEA   A +AE +Y+E +RKL  TE  LE  E   E  E K+ E+  E+  V N+ + LEI+E  A++RE  +E  ++ L + L+DA+ RA EAE  +++ Q  +D+LE+ L  EK  ++ +S++L     E 
Sbjct:   64 LTEAQTKLEASEKHVAELESDTAGLNRRIQLLEEDLERSEERLQSATEKLEEASKAADESERGRKVLESRSLADDERLDGLEAQLKEAKYIAEDAERKYDEAARKLAITEVDLERAEARLEAAEAKIIELEEELKVVGNNMKSLEISEQEASQREDSYEETIRDLTQRLKDAENRATEAERTVSKLQKEVDRLEDELLAEKERYKSISDELDSTFAEL 281
[Close]
BLAST of SMED30014124 vs. UniProt/SwissProt
Match: sp|Q26519|TPM_SCHJA (Tropomyosin OS=Schistosoma japonicum OX=6182 PE=2 SV=1)

HSP 1 Score: 109.383 bits (272), Expect = 2.337e-26
Identity = 80/218 (36.70%), Postives = 127/218 (58.26%), Query Frame = 1 
Query:  148 LHEKETKLKEEQHTRDELDKQVVLLSRKVGVLESDLDDNEKRLQEAKFKLEEITFTAAECERARRQLQSKHDADDERIYHLETLVKEATEQAGEAEARYEEVSRKLIATENVLENTEDEYEKTEKKLREITMEMTSVCNSFRVLEINEARAAEREQKFEVEVKHLKKLLQDADKRANEAENELNQRQMMLDQLEEALDKEKRNHQLLSNDLQRMVEEF 801
            L E+  KL+E +      + QV  ++R++ +LE DL+ +  RL E   KLEE + TA E ER R+ L+ +  ADDER+  LE   KEA   A +A+ +Y+E +RKL   E   E  E   E  E K+ E+  E+  V N+ + LEI+E  +A+RE+ +E  ++ L + L+ A++RA EAE ++++ Q  +D LE+ L  EK  ++ LS +L +   E 
Sbjct:   64 LQEQMNKLEETEKRATNAEAQVAAMTRRIRLLEEDLEVSSSRLTETLTKLEEASKTAEESERGRKDLEIRSIADDERLNQLEDQQKEAKYIAEDADRKYDEAARKLAIAEVDFERAEARLEAAESKIVELEEELRVVGNNMKALEISEQESAQREESYEETIRDLTERLKAAEQRATEAERQVSKLQNEVDHLEDDLLAEKERYKALSGELDQTFAEL 281
[Close]
BLAST of SMED30014124 vs. TrEMBL
Match: G4VN72 (Putative tropomyosin OS=Schistosoma mansoni OX=6183 GN=Smp_031770.14 PE=4 SV=1)

HSP 1 Score: 127.102 bits (318), Expect = 1.553e-30
Identity = 88/219 (40.18%), Postives = 130/219 (59.36%), Query Frame = 1 
Query:  145 QLHEKETKLKEEQHTRDELDKQVVLLSRKVGVLESDLDDNEKRLQEAKFKLEEITFTAAECERARRQLQSKHDADDERIYHLETLVKEATEQAGEAEARYEEVSRKLIATENVLENTEDEYEKTEKKLREITMEMTSVCNSFRVLEINEARAAEREQKFEVEVKHLKKLLQDADKRANEAENELNQRQMMLDQLEEALDKEKRNHQLLSNDLQRMVEEF 801
            QL E  TKL+E      E + +V  L +++  LE +L+  E RLQEA  KLEE +  A E +RARR L+++  A+DERI HLE++V+E  +   +AE +YEE +RKL  TE  LE  E   E  E K+ E+  E+  V N+ + LEI+E  AA+RE+ +E  ++ L + L+ A+ RA E+E  +N  Q   D+LE+ L  EK  ++ LS +L     E 
Sbjct:   63 QLAETNTKLEETDKRATEAEAEVASLQKRIRQLEDELESTETRLQEATVKLEEASKAADESDRARRVLEARQTAEDERILHLESVVQETAKSVRDAETKYEEAARKLAITEVELERAESRLEAAESKITELEEELRIVGNNVKSLEISEQEAAQREEAYEENIRDLTERLKAAEDRAQESERLVNTLQADADRLEDELVTEKEKYKALSEELDSTFAEL 281
[Close]
BLAST of SMED30014124 vs. TrEMBL
Match: A0A4Z2DR93 (Tropomyosin-2 isoform 5 OS=Schistosoma japonicum OX=6182 GN=EWB00_009968 PE=4 SV=1)

HSP 1 Score: 126.716 bits (317), Expect = 2.782e-30
Identity = 86/219 (39.27%), Postives = 129/219 (58.90%), Query Frame = 1 
Query:  145 QLHEKETKLKEEQHTRDELDKQVVLLSRKVGVLESDLDDNEKRLQEAKFKLEEITFTAAECERARRQLQSKHDADDERIYHLETLVKEATEQAGEAEARYEEVSRKLIATENVLENTEDEYEKTEKKLREITMEMTSVCNSFRVLEINEARAAEREQKFEVEVKHLKKLLQDADKRANEAENELNQRQMMLDQLEEALDKEKRNHQLLSNDLQRMVEEF 801
            QL E  TKL+E      E + +V  L +++  LE +L+  E RLQEA  KLEE +  A E +RARR L+++  A+DERI  LE++V+E  +   +AE +YEE +RKL   E  L + ED  E  E K+ E+  E+  V N+ + LEI+E  AA+RE+ +E  ++ L + L+ A+ RA E+E  +N  Q   D+LE+ L  EK  ++ LS +L     E 
Sbjct:   63 QLAETNTKLEETDKRATEAEAEVASLQKRIRQLEDELESTETRLQEATLKLEEASKAADESDRARRVLEARQTAEDERILQLESMVQETAKSVKDAETKYEEATRKLAVAEVALSHAEDRIEAAESKITELEEELRIVGNNVKSLEISEQEAAQREEAYEENIRDLTERLKAAEDRAQESERLVNTLQADADRLEDELVTEKEKYKALSEELDSTFAEL 281
[Close]
BLAST of SMED30014124 vs. TrEMBL
Match: A0A2C9K1S9 (Uncharacterized protein OS=Biomphalaria glabrata OX=6526 GN=106078167 PE=3 SV=1)

HSP 1 Score: 122.479 bits (306), Expect = 5.440e-29
Identity = 78/202 (38.61%), Postives = 130/202 (64.36%), Query Frame = 1 
Query:  196 ELDKQVVLLSRKVGVLESDLDDNEKRLQEAKFKLEEITFTAAECERARRQLQSKHDADDERIYHLETLVKEATEQAGEAEARYEEVSRKLIATENVLENTEDEYEKTEKKLREITMEMTSVCNSFRVLEINEARAAEREQKFEVEVKHLKKLLQDADKRANEAENELNQRQMMLDQLEEALDKEKRNHQLLSNDLQRMVEEF 801
            +L+     L+R++ +LE DL+ +E+RLQ A  KLEE +  A E ER RR +++K +A DER+   ETL+++A + A E+EARY+E +RKL+  EN LE  E+  E  E+K++ +  E+ ++ N+ R LE  E +A++RE  +E  ++ L + L+DA+ RA EAE  +++ Q  +D+LE+ L  EK  ++ +S++L     E 
Sbjct:   48 QLESDTAGLNRRIQLLEEDLERSEERLQSATEKLEEASKAADESERQRRTVENKLNAGDERLEEAETLLRQARQVASESEARYDEAARKLVVLENELEKAEERAENAERKVKALEAEVHALTNNLRSLERCEEKASQREDSYEETIRDLTQRLKDAENRATEAERTVSKLQKEVDRLEDELLAEKERYKSISDELDSTFAEL 249
[Close]
BLAST of SMED30014124 vs. TrEMBL
Match: A0A564Z0F8 (Uncharacterized protein OS=Hymenolepis diminuta OX=6216 GN=WMSIL1_LOCUS11345 PE=4 SV=1)

HSP 1 Score: 121.709 bits (304), Expect = 8.760e-29
Identity = 76/214 (35.51%), Postives = 129/214 (60.28%), Query Frame = 1 
Query:  169 LKEEQHTRDELDKQVVLLSRKVGVLESDLDDNEKRLQEAKFKLEEITFTAAECERARRQLQSKHDADDERIYHLETLVKEATEQAGEAEARYEEVSRKLIATENVLENTEDEYEKTEKKLREITMEMTSVCNSFRVLEINEARAAEREQKFEVEVKHLKKLLQDADKRANEAENELNQRQMMLDQLEEALDKEKRNHQLLSNDLQRMVEEFQQM 810
            LKEE+  RD+ + +V  L R++ +LE DL+  + RL +A  KLEE +  A E ER RR LQS+   DD RI  L+  +++  ++A EAE +Y+E ++KL   E+ L   E   E  E ++R +  E+ ++  + + +E++E+ A++++Q ++  ++ L K L +A+KR   AE E+ +RQ  L +LE  LD EK  +  L  D++ +V E Q +
Sbjct:   38 LKEEKDKRDKAEAEVAALQRRIRLLEDDLESTDTRLTDATAKLEEASKAADESERFRRALQSRQVTDDSRIEQLQQRIQKTAKEAAEAERKYQEATQKLATAEDALSAAEKRVEDAEDRIRSMEHELRAITTNLKTMELSESTASKQKQTYQATLEKLTKQLAEAEKRTERAEEEMTRRQEELTRLEAELDMEKTLNASLREDMESIVAELQNL 251
[Close]
BLAST of SMED30014124 vs. TrEMBL
Match: A0A1S3J6B1 (tropomyosin-2 isoform X5 OS=Lingula unguis OX=7574 GN=LOC106170578 PE=4 SV=1)

HSP 1 Score: 119.398 bits (298), Expect = 1.348e-27
Identity = 83/218 (38.07%), Postives = 131/218 (60.09%), Query Frame = 1 
Query:  148 LHEKETKLKEEQHTRDELDKQVVLLSRKVGVLESDLDDNEKRLQEAKFKLEEITFTAAECERARRQLQSKHDADDERIYHLETLVKEATEQAGEAEARYEEVSRKLIATENVLENTEDEYEKTEKKLREITMEMTSVCNSFRVLEINEARAAEREQKFEVEVKHLKKLLQDADKRANEAENELNQRQMMLDQLEEALDKEKRNHQLLSNDLQRMVEEF 801
            L    TKL+  +  + E ++QV  L+R+V +LE +L+  E+RL  A  KL+E +  A E ERAR+ L+++++ DD+RI  LE +V+EATE A EAE +++EV+RKL  TE  LE  ED  +  E K++ +  E+  V ++ + L INE +A+ RE  +E  ++ L    ++A+ RA EAE  + + Q  +D LE  L+ EK     LS +L+    E 
Sbjct:   64 LQNATTKLEASEKAQGEAEEQVQTLNRRVLLLEENLESTEERLTAASSKLDEASQAADESERARKVLENRNNIDDDRIGMLEQMVREATETADEAERKFDEVTRKLTITEADLERAEDRADNAEAKIKALEEELHVVSHNLKSLSINEEKASAREDSYEETIRDLTARSKEAEHRAGEAERTVAKLQKDVDNLEGELEAEKEKLNSLSAELEATFTEL 281
[Close]
BLAST of SMED30014124 vs. Ensembl Cavefish
Match: tpm1 (tropomyosin 1 [Source:NCBI gene;Acc:103046255])

HSP 1 Score: 92.8189 bits (229), Expect = 2.727e-21
Identity = 74/203 (36.45%), Postives = 122/203 (60.10%), Query Frame = 1 
Query:  175 EEQHTRDELDKQVVLLSRKVGVLESDLDDNEKRLQEAKFKLEEITFTAAECERARRQLQSKHDADDERIYHLETLVKEATEQAGEAEARYEEVSRKLIATENVLENTEDEYEKTEKKLREITMEMTSVCNSFRVLEINEARAAEREQKFEVEVKHLKKLLQDADKRANEAENELNQRQMMLDQLEEALDKEKRNHQLLSNDLQ 783
            EE  T+ E D  V  L+R++ ++E +LD  ++RL  A  KLEE    A E ER  + ++++   D+E++   E  +KEA   A EA+ +YEEV+RKL+  E  LE TE+  E +E K  E+  E+ +V N+ + LE    + +++E K+E E+K L   L++A+ RA  AE  + + +  +D LE+ L ++   ++LLSNDL+
Sbjct:   75 EEVATKAEGD--VASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKYEEVARKLVIVEGELERTEERAELSESKCAELEEELKTVTNTLKSLEAQAEKYSQKEDKYEEEIKVLTDKLKEAETRAEFAERSVAKLEKTIDDLEDLLYQQLEKNRLLSNDLR 275
[Close]
BLAST of SMED30014124 vs. Ensembl Cavefish
Match: tpm1 (tropomyosin 1 [Source:NCBI gene;Acc:103046255])

HSP 1 Score: 86.2705 bits (212), Expect = 5.537e-19
Identity = 66/190 (34.74%), Postives = 113/190 (59.47%), Query Frame = 1 
Query:  211 VVLLSRKVGVLESDLDDNEKRLQEAKFKLEEITFTAAECERARRQLQSKHDADDERIYHLETLVKEATEQAGEAEARYEEVSRKLIATENVLENTEDEYEKTEKKLREITMEMTSVCNSFRVLEINEARAAEREQKFEVEVKHLKKLLQDADKRANEAENELNQRQMMLDQLEEALDKEKRNHQLLSNDL 780
            V  L+R++ ++E +LD  ++RL  A  KLEE    A E ER  + ++++   D+E++   E  +KEA   A EA+ +YEEV+RKL+  E  LE TE+  E +E K  E+  E+ +V N+ + LE    + +++E K+E E+K L   L++A+ RA  AE  + + +  +D LE+ L  +K  ++ +S +L
Sbjct:   85 VASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKYEEVARKLVIVEGELERTEERAELSESKCAELEEELKTVTNTLKSLEAQAEKYSQKEDKYEEEIKVLTDKLKEAETRAEFAERSVAKLEKTIDDLEDELYAQKLKYKAISEEL 274
[Close]
BLAST of SMED30014124 vs. Ensembl Cavefish
Match: tpm1 (tropomyosin 1 [Source:NCBI gene;Acc:103046255])

HSP 1 Score: 86.2705 bits (212), Expect = 5.537e-19
Identity = 66/190 (34.74%), Postives = 113/190 (59.47%), Query Frame = 1 
Query:  211 VVLLSRKVGVLESDLDDNEKRLQEAKFKLEEITFTAAECERARRQLQSKHDADDERIYHLETLVKEATEQAGEAEARYEEVSRKLIATENVLENTEDEYEKTEKKLREITMEMTSVCNSFRVLEINEARAAEREQKFEVEVKHLKKLLQDADKRANEAENELNQRQMMLDQLEEALDKEKRNHQLLSNDL 780
            V  L+R++ ++E +LD  ++RL  A  KLEE    A E ER  + ++++   D+E++   E  +KEA   A EA+ +YEEV+RKL+  E  LE TE+  E +E K  E+  E+ +V N+ + LE    + +++E K+E E+K L   L++A+ RA  AE  + + +  +D LE+ L  +K  ++ +S +L
Sbjct:   85 VASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKYEEVARKLVIVEGELERTEERAELSESKCAELEEELKTVTNTLKSLEAQAEKYSQKEDKYEEEIKVLTDKLKEAETRAEFAERSVAKLEKTIDDLEDELYAQKLKYKAISEEL 274
[Close]
BLAST of SMED30014124 vs. Ensembl Cavefish
Match: tpm1 (tropomyosin 1 [Source:NCBI gene;Acc:103046255])

HSP 1 Score: 84.3445 bits (207), Expect = 2.739e-18
Identity = 68/188 (36.17%), Postives = 111/188 (59.04%), Query Frame = 1 
Query:  175 EEQHTRDELDKQVVLLSRKVGVLESDLDDNEKRLQEAKFKLEEITFTAAECERARRQLQSKHDADDERIYHLETLVKEATEQAGEAEARYEEVSRKLIATENVLENTEDEYEKTEKKLREITMEMTSVCNSFRVLEINEARAAEREQKFEVEVKHLKKLLQDADKRANEAENELNQRQMMLDQLEEAL 738
            EE  T+ E D  V  L+R++ ++E +LD  ++RL  A  KLEE    A E ER  + ++++   D+E++   E  +KEA   A EA+ +YEEV+RKL+  E  LE TE+  E +E K  E+  E+ +V N+ + LE    + +++E K+E E+K L   L++A+ RA  AE  + + +  +D LE+ L
Sbjct:   75 EEVATKAEGD--VASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKYEEVARKLVIVEGELERTEERAELSESKCAELEEELKTVTNTLKSLEAQAEKYSQKEDKYEEEIKVLTDKLKEAETRAEFAERSVAKLEKTIDDLEDKL 260
[Close]
BLAST of SMED30014124 vs. Ensembl Cavefish
Match: tpma (tropomyosin alpha-1 chain [Source:NCBI gene;Acc:103040917])

HSP 1 Score: 84.3445 bits (207), Expect = 3.051e-18
Identity = 66/190 (34.74%), Postives = 111/190 (58.42%), Query Frame = 1 
Query:  211 VVLLSRKVGVLESDLDDNEKRLQEAKFKLEEITFTAAECERARRQLQSKHDADDERIYHLETLVKEATEQAGEAEARYEEVSRKLIATENVLENTEDEYEKTEKKLREITMEMTSVCNSFRVLEINEARAAEREQKFEVEVKHLKKLLQDADKRANEAENELNQRQMMLDQLEEALDKEKRNHQLLSNDL 780
            V  L+R++ ++E +LD  ++RL  A  KLEE    A E ER  + ++++   D+E++   E  +KEA   A EA+ +YEEV+RKL+  E  LE TE+  E  E K  E+  E+ +V N  + LE    + +++E K+E E+K L   L++A+ RA  AE  + + +  +D LE+ L  +K  ++ +S +L
Sbjct:   85 VASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIENRALKDEEKMEIQEIQLKEAKHIAEEADRKYEEVARKLVIVEGELERTEERAELNEGKCSELEEELKTVTNLLKSLEAQAEKYSQKEDKYEEEIKVLTDKLKEAETRAEFAERSVAKLEKTIDDLEDELYSQKLKYKAISEEL 274
[Close]
BLAST of SMED30014124 vs. Ensembl Sea Lamprey
Match: TPM4 (tropomyosin 4 [Source:HGNC Symbol;Acc:HGNC:12013])

HSP 1 Score: 82.4185 bits (202), Expect = 6.903e-19
Identity = 64/190 (33.68%), Postives = 114/190 (60.00%), Query Frame = 1 
Query:  211 VVLLSRKVGVLESDLDDNEKRLQEAKFKLEEITFTAAECERARRQLQSKHDADDERIYHLETLVKEATEQAGEAEARYEEVSRKLIATENVLENTEDEYEKTEKKLREITMEMTSVCNSFRVLEINEARAAEREQKFEVEVKHLKKLLQDADKRANEAENELNQRQMMLDQLEEALDKEKRNHQLLSNDL 780
            V  L+R++ ++E +LD  ++RL  A  KLEE T  A E ER  + ++++   D+E++   E  +KEA   A EA+ +YEEV+RKL+  E  LE TE+  E  E ++R++  E+  +  + + L + E + +++E K+E E+K L   L++A+ RA  AE  + + +  +D LE+ L  +K  ++ +S +L
Sbjct:    7 VASLNRRIQLVEEELDRAQERLATALQKLEEATKAADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKYEEVARKLVIIEGELERTEERAEVGETRVRQLEEELRVMDQNMKSLLVAEEQYSQKEDKYEEEIKILTDKLKEAETRAEFAERSVAKLEKTIDDLEDELYSQKLKYKAISEEL 196
[Close]
BLAST of SMED30014124 vs. Ensembl Sea Lamprey
Match: tpm3 (tropomyosin 3 [Source:ZFIN;Acc:ZDB-GENE-030826-16])

HSP 1 Score: 81.2629 bits (199), Expect = 2.259e-18
Identity = 63/190 (33.16%), Postives = 111/190 (58.42%), Query Frame = 1 
Query:  211 VVLLSRKVGVLESDLDDNEKRLQEAKFKLEEITFTAAECERARRQLQSKHDADDERIYHLETLVKEATEQAGEAEARYEEVSRKLIATENVLENTEDEYEKTEKKLREITMEMTSVCNSFRVLEINEARAAEREQKFEVEVKHLKKLLQDADKRANEAENELNQRQMMLDQLEEALDKEKRNHQLLSNDL 780
            V  L+R++ ++E +LD  ++RL  A  KLEE    A E ER  + ++++   D+E++   E  +KEA   A E++ +YEEV+RKL+  E  LE TE+  E  + K  E+  E+  V N+ + LE    + +++E K+E E+K L   L++A+ RA  AE  + + +  +D LE+ +  +K  ++ +S +L
Sbjct:    6 VASLNRRIQLVEEELDRAQERLSTALQKLEEAEKAADESERGMKVIENRASKDEEKMELQEIQLKEAKHIAEESDRKYEEVARKLVILEGDLERTEERAEVADAKCSELEEELKVVTNNLKSLEAQSDKYSQKEDKYEEEIKILTDKLKEAETRAEFAERSVAKLEKSIDDLEDEVYAQKLKYKSVSEEL 195
[Close]
BLAST of SMED30014124 vs. Ensembl Sea Lamprey
Match: TPM4 (tropomyosin 4 [Source:HGNC Symbol;Acc:HGNC:12013])

HSP 1 Score: 77.411 bits (189), Expect = 2.473e-17
Identity = 60/173 (34.68%), Postives = 103/173 (59.54%), Query Frame = 1 
Query:  211 VVLLSRKVGVLESDLDDNEKRLQEAKFKLEEITFTAAECERARRQLQSKHDADDERIYHLETLVKEATEQAGEAEARYEEVSRKLIATENVLENTEDEYEKTEKKLREITMEMTSVCNSFRVLEINEARAAEREQKFEVEVKHLKKLLQDADKRANEAENELNQRQMMLDQLE 729
            V  L+R++ ++E +LD  ++RL  A  KLE+    A E ER  + ++++   D+E++   E  +KEA   A EA+ +YEEV+RKL+  E  LE TE+  E +E ++R++  E+  V    R L  +E + +++E K+E E+K L   L++A+ RA  AE  + + +  +D LE
Sbjct:    6 VASLNRRIQLVEEELDRAQERLTTALQKLEDAEKAADESERGMKVIENRAGKDEEKMELQEIQLKEAKHIAEEADRKYEEVARKLVIIEGDLERTEERAEISETRVRQMEDELRHVQEELRSLFASEEQYSQKEDKYEEEIKVLTDKLKEAETRAEFAERSVAKLEKTIDDLE 178
[Close]
BLAST of SMED30014124 vs. Ensembl Nematostella
Match: EDO37230 (Predicted protein; Tropomyosin [Source:UniProtKB/TrEMBL;Acc:Q6S5G5])

HSP 1 Score: 86.6557 bits (213), Expect = 7.293e-20
Identity = 67/176 (38.07%), Postives = 109/176 (61.93%), Query Frame = 1 
Query:  160 ETKLKEEQHTRDELDKQVVLLSRKVGVLESDLDDNEKRLQEAKFKLEEITFTAAECERARRQLQSKHDADDERIYHLETLVKEATEQAGEAEARYEEVSRKLIATENVLENTEDEYEKTEKKLREITMEMTSVCNSFRVLEINEARAAEREQKFEVEVKHLKKLLQDADKRANEAE 687
            E +LK      D  + +V  L++++  LE DLD  E +L + + +L E    A E ERAR+ L+++  +D+ER+  LE    +A E+  EAE +YEE+S +L   EN LE  E + +  E +++E+  E+T V N+ R LEI+E +A+ERE  +E +++ L+  LQDA++RA +AE
Sbjct:   26 EDELKNANDRADSAETEVAALTKQLQQLEDDLDAAESKLADTQGQLTEAEKQADESERARKVLENRGASDEERLASLERQYNDALERTEEAEKQYEEISERLQELENELEEAEQKADAAEARVKELEEEVTLVGNNLRSLEISEGKASEREDTYENQIRELETKLQDAEERAEKAE 201
[Close]
BLAST of SMED30014124 vs. Ensembl Medaka
Match: ENSORLT00000015430.2 (tropomyosin alpha-1 chain [Source:NCBI gene;Acc:101164789])

HSP 1 Score: 92.0485 bits (227), Expect = 3.080e-21
Identity = 71/204 (34.80%), Postives = 123/204 (60.29%), Query Frame = 1 
Query:  169 LKEEQHTRDELDKQVVLLSRKVGVLESDLDDNEKRLQEAKFKLEEITFTAAECERARRQLQSKHDADDERIYHLETLVKEATEQAGEAEARYEEVSRKLIATENVLENTEDEYEKTEKKLREITMEMTSVCNSFRVLEINEARAAEREQKFEVEVKHLKKLLQDADKRANEAENELNQRQMMLDQLEEALDKEKRNHQLLSNDL 780
            L +E+  R+  +  V  L+R++ ++E +LD  ++RL  A  KLEE    A E ER  + ++++   D+E++   E  +KEA   A EA+ +YEEV+RKL+  E+ LE TE+  E +E K  E+  E+ +V N+ + LE    + +++E K+E E+K L   L++A+ RA  AE  + + +  +D LE+ L K+   ++LL+N+L
Sbjct:   35 LNQERSAREAAEGDVASLNRRIQLVEEELDRAQERLATALTKLEEAEKAADESERGMKVIENRAMKDEEKMELQEIQLKEAKHIAEEADRKYEEVARKLVIIESDLERTEERAELSEGKCSELEEELKTVQNNLKSLEAQAEKYSQKEDKYEEEIKVLTDKLKEAETRAEFAERSVAKLEKTIDDLEDHLYKQLEKNRLLTNEL 238
[Close]
BLAST of SMED30014124 vs. Ensembl Medaka
Match: ENSORLT00000046199.1 (tropomyosin alpha-1 chain [Source:NCBI gene;Acc:101164789])

HSP 1 Score: 88.9669 bits (219), Expect = 3.906e-20
Identity = 69/204 (33.82%), Postives = 121/204 (59.31%), Query Frame = 1 
Query:  169 LKEEQHTRDELDKQVVLLSRKVGVLESDLDDNEKRLQEAKFKLEEITFTAAECERARRQLQSKHDADDERIYHLETLVKEATEQAGEAEARYEEVSRKLIATENVLENTEDEYEKTEKKLREITMEMTSVCNSFRVLEINEARAAEREQKFEVEVKHLKKLLQDADKRANEAENELNQRQMMLDQLEEALDKEKRNHQLLSNDL 780
            L +E+  R+  +  V  L+R++ ++E +LD  ++RL  A  KLEE    A E ER  + ++++   D+E++   E  +KEA   A EA+ +YEEV+RKL+  E+ LE TE+  E +E K  E+  E+ +V N+ + LE    + +++E K+E E+K L   L++A+ RA  AE  + + +  +D LE+ L  +K  ++ +S +L
Sbjct:   35 LNQERSAREAAEGDVASLNRRIQLVEEELDRAQERLATALTKLEEAEKAADESERGMKVIENRAMKDEEKMELQEIQLKEAKHIAEEADRKYEEVARKLVIIESDLERTEERAELSEGKCSELEEELKTVQNNLKSLEAQAEKYSQKEDKYEEEIKVLTDKLKEAETRAEFAERSVAKLEKTIDDLEDELYSQKLKYKAISEEL 238
[Close]
BLAST of SMED30014124 vs. Ensembl Medaka
Match: ENSORLT00000024131.2 (tropomyosin alpha-3 chain [Source:NCBI gene;Acc:101168689])

HSP 1 Score: 88.1965 bits (217), Expect = 8.404e-20
Identity = 65/208 (31.25%), Postives = 123/208 (59.13%), Query Frame = 1 
Query:  178 EQHTRDELDKQVVLLSRKVGVLESDLDDNEKRLQEAKFKLEEITFTAAECERARRQLQSKHDADDERIYHLETLVKEATEQAGEAEARYEEVSRKLIATENVLENTEDEYEKTEKKLREITMEMTSVCNSFRVLEINEARAAEREQKFEVEVKHLKKLLQDADKRANEAENELNQRQMMLDQLEEALDKEKRNHQLLSNDLQRMVEEF 801
            E+ +R+E + +V  L R++ + E +LD   +RL  A  KL+E+   A E ER  + ++++   D+E++  LE  ++EA + A EA+ +YEEV+RKL+  E  LE  ED  E+ + K+R +  ++ S   S + L+ +E + + +E ++E E+K+L   L++A+ RA  +E  + + +  +D LE+AL   +  +  L   L++ ++E 
Sbjct:   39 EKRSREEAEAEVSSLGRRLQLSEENLDRVHERLGAALLKLDEVEKVADESERGMKVIENRALKDEEKMELLEVQLREAKQIAEEADRKYEEVARKLVIVEGELERAEDRAEQADSKVRRLEEQLRSYDQSLKSLQASEDKYSLKEDRYEEEIKNLSNKLKEAEARAELSERTVTKLEKTIDGLEDALTAARNANMELQATLKQTMDEL 246
[Close]
BLAST of SMED30014124 vs. Ensembl Medaka
Match: TPM1 (tropomyosin 1 [Source:NCBI gene;Acc:101168205])

HSP 1 Score: 87.0409 bits (214), Expect = 3.713e-19
Identity = 74/206 (35.92%), Postives = 118/206 (57.28%), Query Frame = 1 
Query:  175 EEQHTRDELDKQVVLLSRKVGVLESDLDDNEKRLQEAKFKLEEITFTAAECERARRQLQSKHDADDERIYHLETLVKEATEQAGEAEARYEEVSRKLIATENVLENTEDEYEKTEKKLREITMEMTSVCNSFRVLEINEARAAEREQKFEVEVKHLKKLLQDADKRANEAENELNQRQMMLDQLEEALDKEKRN----HQLLSNDL 780
            EE  T+ E D  V  L+R++ ++E +LD  ++RL  A  KLEE    A E ER  + ++++   D+E++   E  +KEA   A EA+ +YEEV+RKL+  E+ LE TE+  E +E K  E+  E+ +V N+ + LE    + + +E K+E E+K L   L++A+ RA  AE  + + +  +D LEE L + K      HQ+L   L
Sbjct:   75 EETATKAESD--VASLNRRIQLVEEELDRAQERLATALTKLEEAEKAADESERGMKVIENRAMKDEEKMEIQEIQLKEAKHIAEEADRKYEEVARKLVIIESDLERTEERAELSEGKCSELEEELKTVTNNLKSLEAQAEKYSLKEDKYEEEIKVLTDKLKEAETRAEFAERSVAKLEKTIDDLEEKLSQAKEENIDMHQMLDQTL 278
[Close]
BLAST of SMED30014124 vs. Ensembl Medaka
Match: TPM1 (tropomyosin 1 [Source:NCBI gene;Acc:101168205])

HSP 1 Score: 85.8853 bits (211), Expect = 4.220e-19
Identity = 69/204 (33.82%), Postives = 119/204 (58.33%), Query Frame = 1 
Query:  169 LKEEQHTRDELDKQVVLLSRKVGVLESDLDDNEKRLQEAKFKLEEITFTAAECERARRQLQSKHDADDERIYHLETLVKEATEQAGEAEARYEEVSRKLIATENVLENTEDEYEKTEKKLREITMEMTSVCNSFRVLEINEARAAEREQKFEVEVKHLKKLLQDADKRANEAENELNQRQMMLDQLEEALDKEKRNHQLLSNDL 780
            L E +  R+  +  V  L+R++ ++E +LD  ++RL  A  KLEE    A E ER  + ++++   D+E++   E  +KEA   A EA+ +YEEV+RKL+  E+ LE TE+  E +E K  E+  E+ +V N+ + LE    + + +E K+E E+K L   L++A+ RA  AE  + + +  +D LE+ L  +K  ++ +S +L
Sbjct:   35 LLEYRKAREHAESDVASLNRRIQLVEEELDRAQERLATALTKLEEAEKAADESERGMKVIENRAMKDEEKMEIQEIQLKEAKHIAEEADRKYEEVARKLVIIESDLERTEERAELSEGKCSELEEELKTVTNNLKSLEAQAEKYSLKEDKYEEEIKVLTDKLKEAETRAEFAERSVAKLEKTIDDLEDELYSQKLKYKAISEEL 238
[Close]
BLAST of SMED30014124 vs. Planmine SMEST
Match: SMESG000024190.1 (SMESG000024190.1)

HSP 1 Score: 449.514 bits (1155), Expect = 1.436e-160
Identity = 249/249 (100.00%), Postives = 249/249 (100.00%), Query Frame = 1 
Query:   64 MNETVELVIVFXXXXXXXXXXXXXXXXQLHEKETKLKEEQHTRDELDKQVVLLSRKVGVLESDLDDNEKRLQEAKFKLEEITFTAAECERARRQLQSKHDADDERIYHLETLVKEATEQAGEAEARYEEVSRKLIATENVLENTEDEYEKTEKKLREITMEMTSVCNSFRVLEINEARAAEREQKFEVEVKHLKKLLQDADKRANEAENELNQRQMMLDQLEEALDKEKRNHQLLSNDLQRMVEEFQQM 810
            MNETVELVIVFKKKIEELRKEIEVLEVQLHEKETKLKEEQHTRDELDKQVVLLSRKVGVLESDLDDNEKRLQEAKFKLEEITFTAAECERARRQLQSKHDADDERIYHLETLVKEATEQAGEAEARYEEVSRKLIATENVLENTEDEYEKTEKKLREITMEMTSVCNSFRVLEINEARAAEREQKFEVEVKHLKKLLQDADKRANEAENELNQRQMMLDQLEEALDKEKRNHQLLSNDLQRMVEEFQQM
Sbjct:    1 MNETVELVIVFKKKIEELRKEIEVLEVQLHEKETKLKEEQHTRDELDKQVVLLSRKVGVLESDLDDNEKRLQEAKFKLEEITFTAAECERARRQLQSKHDADDERIYHLETLVKEATEQAGEAEARYEEVSRKLIATENVLENTEDEYEKTEKKLREITMEMTSVCNSFRVLEINEARAAEREQKFEVEVKHLKKLLQDADKRANEAENELNQRQMMLDQLEEALDKEKRNHQLLSNDLQRMVEEFQQM 249
[Close]
BLAST of SMED30014124 vs. Planmine SMEST
Match: SMESG000074053.1 (SMESG000074053.1)

HSP 1 Score: 118.242 bits (295), Expect = 9.442e-31
Identity = 82/211 (38.86%), Postives = 132/211 (62.56%), Query Frame = 1 
Query:  148 LHEKETKLKEEQHTRDELDKQVVLLSRKVGVLESDLDDNEKRLQEAKFKLEEITFTAAECERARRQLQSKHDADDERIYHLETLVKEATEQAGEAEARYEEVSRKLIATENVLENTEDEYEKTEKKLREITMEMTSVCNSFRVLEINEARAAEREQKFEVEVKHLKKLLQDADKRANEAENELNQRQMMLDQLEEALDKEKRNHQLLSNDL 780
            L E  TKL+  +    + + +V  L+R++ ++E+DL+  E R QEA  KLEE +  A E E+ R+ L+++  ADDE++  LE  VKEA   A +A+ +Y+EV+RKL   E  LE TE   E  E K  E+  E+  V N+ + LEI+E  AA+RE+ +E  ++ L + L+ A++RA EAE ++++ Q  +D+LE+ L  EK  ++ LS++L
Sbjct:   57 LAEANTKLEATEKRATDAEAEVAALTRRIQLIEADLEQTESRFQEASAKLEEASKNAEESEKNRKILETRSIADDEKLAQLEEQVKEAKYIAEDADRKYDEVARKLAIAEVDLERTEARLENCESKTLELEEELKVVGNNMKSLEISEQEAAQREESYEDTIRDLTERLKAAEQRATEAERQVSKLQSEVDRLEDDLLSEKEKYKALSDEL 267
[Close]
BLAST of SMED30014124 vs. Planmine SMEST
Match: SMESG000074053.1 (SMESG000074053.1)

HSP 1 Score: 118.242 bits (295), Expect = 1.087e-30
Identity = 82/211 (38.86%), Postives = 132/211 (62.56%), Query Frame = 1 
Query:  148 LHEKETKLKEEQHTRDELDKQVVLLSRKVGVLESDLDDNEKRLQEAKFKLEEITFTAAECERARRQLQSKHDADDERIYHLETLVKEATEQAGEAEARYEEVSRKLIATENVLENTEDEYEKTEKKLREITMEMTSVCNSFRVLEINEARAAEREQKFEVEVKHLKKLLQDADKRANEAENELNQRQMMLDQLEEALDKEKRNHQLLSNDL 780
            L E  TKL+  +    + + +V  L+R++ ++E+DL+  E R QEA  KLEE +  A E E+ R+ L+++  ADDE++  LE  VKEA   A +A+ +Y+EV+RKL   E  LE TE   E  E K  E+  E+  V N+ + LEI+E  AA+RE+ +E  ++ L + L+ A++RA EAE ++++ Q  +D+LE+ L  EK  ++ LS++L
Sbjct:   64 LAEANTKLEATEKRATDAEAEVAALTRRIQLIEADLEQTESRFQEASAKLEEASKNAEESEKNRKILETRSIADDEKLAQLEEQVKEAKYIAEDADRKYDEVARKLAIAEVDLERTEARLENCESKTLELEEELKVVGNNMKSLEISEQEAAQREESYEDTIRDLTERLKAAEQRATEAERQVSKLQSEVDRLEDDLLSEKEKYKALSDEL 274
[Close]
BLAST of SMED30014124 vs. Planmine SMEST
Match: SMESG000041543.1 (SMESG000041543.1)

HSP 1 Score: 114.775 bits (286), Expect = 1.013e-29
Identity = 74/222 (33.33%), Postives = 135/222 (60.81%), Query Frame = 1 
Query:  145 QLHEKETKLKEEQHTRDELDKQVVLLSRKVGVLESDLDDNEKRLQEAKFKLEEITFTAAECERARRQLQSKHDADDERIYHLETLVKEATEQAGEAEARYEEVSRKLIATENVLENTEDEYEKTEKKLREITMEMTSVCNSFRVLEINEARAAEREQKFEVEVKHLKKLLQDADKRANEAENELNQRQMMLDQLEEALDKEKRNHQLLSNDLQRMVEEFQQM 810
            ++ EK+  L+EE H +  +D+++  L++K+  LES  D+ +++L  +  +L+E++  A   ER RR L+S+   +D +I  LE+ ++EA      A  +Y+E+S+ L  +E  L   ED  E   K+L+E   EM  V ++ + +E+NE++A  RE+ +E ++  +   L+DA  R    E++  ++  +L+ LEE +++EK NH  L NDL++M+EEFQ +
Sbjct:   28 KIEEKDKLLQEEIHKKSSIDQEIETLNKKIRELESQTDELDEKLSLSSIELDEVSKRADINERTRRGLESRKQNNDSKICKLESQLQEALNLKAAANKKYDEISKALKDSEMKLAEAEDRSEAATKRLKETDSEMHGVSHTLKSMELNESKATLREENYEKQINKITLQLKDAQTRYEIQESDYKRQVTLLENLEEQVEQEKENHYKLKNDLEKMMEEFQNI 249
[Close]
BLAST of SMED30014124 vs. Planmine SMEST
Match: SMESG000000190.1 (SMESG000000190.1)

HSP 1 Score: 100.908 bits (250), Expect = 2.342e-24
Identity = 71/195 (36.41%), Postives = 116/195 (59.49%), Query Frame = 1 
Query:  196 ELDKQVVLLSRKVGVLESDLDDNEKRLQEAKFKLEEITFTAAECERARRQLQSKHDADDERIYHLETLVKEATEQAGEAEARYEEVSRKLIATENVLENTEDEYEKTEKKLREITMEMTSVCNSFRVLEINEARAAEREQKFEVEVKHLKKLLQDADKRANEAENELNQRQMMLDQLEEALDKEKRNHQLLSNDL 780
            E + +V  ++++  +LE DL+  E RLQEA  K EE +  A E ER R+ L+++  AD+ER+  LE  +KEA   A +A+ +Y+E +RKL  TE  LE  E   E  + K+ E+  E+  V N+ + LEI+E  A +RE+ +E  ++     L+  ++RA EAE ++   Q  +D++E+ L  EK  ++ LS +L
Sbjct:   80 EAEGEVQAMTKRTRLLEDDLEQTETRLQEATVKYEEASKAADESERGRKVLETRSIADEERLAQLEEQLKEAKYIAEDADRKYDEAARKLAITEVDLERAESRLESADNKVLELEEELRVVGNNMKSLEISEQEAVQREEVYEETIRDFTDKLKSTEQRATEAERQVATLQTEVDRIEDELLAEKEKYKQLSEEL 274
The following BLAST results are available for this feature:
BLAST of SMED30014124 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5
Match NameE-valueIdentityDescription
TPM34.374e-2135.15tropomyosin 3 [Source:HGNC Symbol;Acc:HGNC:12012][more]
TPM34.374e-2135.15tropomyosin 3 [Source:HGNC Symbol;Acc:HGNC:12012][more]
TPM15.846e-1931.78tropomyosin 1 [Source:HGNC Symbol;Acc:HGNC:12010][more]
TPM37.131e-1934.54tropomyosin 3 [Source:HGNC Symbol;Acc:HGNC:12012][more]
TPM37.586e-1933.66tropomyosin 3 [Source:HGNC Symbol;Acc:HGNC:12012][more]
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BLAST of SMED30014124 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 5
Match NameE-valueIdentityDescription
lev-111.789e-2736.32Tropomyosin isoforms a/b/d/f [Source:UniProtKB/Sw... [more]
lev-117.222e-2735.38Tropomyosin isoforms a/b/d/f [Source:UniProtKB/Sw... [more]
lev-114.577e-2534.88Tropomyosin isoforms a/b/d/f [Source:UniProtKB/Sw... [more]
lev-111.902e-2434.43Tropomyosin isoforms a/b/d/f [Source:UniProtKB/Sw... [more]
lev-113.818e-2336.46Tropomyosin isoforms a/b/d/f [Source:UniProtKB/Sw... [more]
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BLAST of SMED30014124 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Tm13.051e-2234.30gene:FBgn0003721 transcript:FBtr0089960[more]
Tm12.174e-2134.34gene:FBgn0003721 transcript:FBtr0305656[more]
Tm12.747e-2137.07gene:FBgn0003721 transcript:FBtr0305654[more]
Tm12.747e-2137.07gene:FBgn0003721 transcript:FBtr0089964[more]
Tm12.747e-2137.07gene:FBgn0003721 transcript:FBtr0089967[more]
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BLAST of SMED30014124 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
tpm15.560e-2032.71tropomyosin 1 (alpha) [Source:ZFIN;Acc:ZDB-GENE-04... [more]
tpm31.196e-1935.08tropomyosin 3 [Source:ZFIN;Acc:ZDB-GENE-030826-16][more]
tpm11.767e-1933.82tropomyosin 1 (alpha) [Source:ZFIN;Acc:ZDB-GENE-04... [more]
tpm13.282e-1933.96tropomyosin 1 (alpha) [Source:ZFIN;Acc:ZDB-GENE-04... [more]
tpm14.961e-1933.50tropomyosin 1 (alpha) [Source:ZFIN;Acc:ZDB-GENE-04... [more]
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BLAST of SMED30014124 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5
Match NameE-valueIdentityDescription
tpm15.174e-1833.00tropomyosin 1 [Source:NCBI gene;Acc:448541][more]
tpm11.143e-1734.21tropomyosin 1 [Source:NCBI gene;Acc:448541][more]
tpm16.695e-1734.54tropomyosin 1 [Source:NCBI gene;Acc:448541][more]
gucy2d8.073e-1734.12guanylate cyclase 2D, membrane (retina-specific) [... [more]
tpm15.684e-1635.26tropomyosin 1 [Source:NCBI gene;Acc:448541][more]
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BLAST of SMED30014124 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Tpm32.688e-2135.15tropomyosin 3, gamma [Source:MGI Symbol;Acc:MGI:18... [more]
Tpm35.106e-2033.83tropomyosin 3, gamma [Source:MGI Symbol;Acc:MGI:18... [more]
Tpm14.146e-1933.18tropomyosin 1, alpha [Source:MGI Symbol;Acc:MGI:98... [more]
Tpm15.551e-1933.17tropomyosin 1, alpha [Source:MGI Symbol;Acc:MGI:98... [more]
Tpm38.333e-1934.74tropomyosin 3, gamma [Source:MGI Symbol;Acc:MGI:18... [more]
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BLAST of SMED30014124 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|P42638|TPM2_SCHMA3.250e-2839.62Tropomyosin-2 OS=Schistosoma mansoni OX=6183 PE=2 ... [more]
sp|Q25145|TPM_HALRU4.517e-2839.60Tropomyosin OS=Haliotis rufescens OX=6454 PE=2 SV=... [more]
sp|Q9GZ71|TPM_HALDV2.509e-2739.73Tropomyosin OS=Haliotis diversicolor OX=36095 PE=1... [more]
sp|P43689|TPM2_BIOGL2.089e-2639.45Tropomyosin-2 OS=Biomphalaria glabrata OX=6526 PE=... [more]
sp|Q26519|TPM_SCHJA2.337e-2636.70Tropomyosin OS=Schistosoma japonicum OX=6182 PE=2 ... [more]
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BLAST of SMED30014124 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
G4VN721.553e-3040.18Putative tropomyosin OS=Schistosoma mansoni OX=618... [more]
A0A4Z2DR932.782e-3039.27Tropomyosin-2 isoform 5 OS=Schistosoma japonicum O... [more]
A0A2C9K1S95.440e-2938.61Uncharacterized protein OS=Biomphalaria glabrata O... [more]
A0A564Z0F88.760e-2935.51Uncharacterized protein OS=Hymenolepis diminuta OX... [more]
A0A1S3J6B11.348e-2738.07tropomyosin-2 isoform X5 OS=Lingula unguis OX=7574... [more]
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BLAST of SMED30014124 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
tpm12.727e-2136.45tropomyosin 1 [Source:NCBI gene;Acc:103046255][more]
tpm15.537e-1934.74tropomyosin 1 [Source:NCBI gene;Acc:103046255][more]
tpm15.537e-1934.74tropomyosin 1 [Source:NCBI gene;Acc:103046255][more]
tpm12.739e-1836.17tropomyosin 1 [Source:NCBI gene;Acc:103046255][more]
tpma3.051e-1834.74tropomyosin alpha-1 chain [Source:NCBI gene;Acc:10... [more]
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BLAST of SMED30014124 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 3
Match NameE-valueIdentityDescription
TPM46.903e-1933.68tropomyosin 4 [Source:HGNC Symbol;Acc:HGNC:12013][more]
tpm32.259e-1833.16tropomyosin 3 [Source:ZFIN;Acc:ZDB-GENE-030826-16][more]
TPM42.473e-1734.68tropomyosin 4 [Source:HGNC Symbol;Acc:HGNC:12013][more]
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BLAST of SMED30014124 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of SMED30014124 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 1
Match NameE-valueIdentityDescription
EDO372307.293e-2038.07Predicted protein; Tropomyosin [Source:UniProtKB/... [more]
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BLAST of SMED30014124 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5
Match NameE-valueIdentityDescription
ENSORLT00000015430.23.080e-2134.80tropomyosin alpha-1 chain [Source:NCBI gene;Acc:10... [more]
ENSORLT00000046199.13.906e-2033.82tropomyosin alpha-1 chain [Source:NCBI gene;Acc:10... [more]
ENSORLT00000024131.28.404e-2031.25tropomyosin alpha-3 chain [Source:NCBI gene;Acc:10... [more]
TPM13.713e-1935.92tropomyosin 1 [Source:NCBI gene;Acc:101168205][more]
TPM14.220e-1933.82tropomyosin 1 [Source:NCBI gene;Acc:101168205][more]
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BLAST of SMED30014124 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5
Match NameE-valueIdentityDescription
SMESG000024190.11.436e-160100.00SMESG000024190.1[more]
SMESG000074053.19.442e-3138.86SMESG000074053.1[more]
SMESG000074053.11.087e-3038.86SMESG000074053.1[more]
SMESG000041543.11.013e-2933.33SMESG000041543.1[more]
SMESG000000190.12.342e-2436.41SMESG000000190.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30014124 ID=SMED30014124|Name=SMED30014124|organism=Schmidtea mediterranea sexual|type=transcript|length=1050bp
TATGCGTCAAAGTATGTTTATTTCATAAATAAATATTATTTATTAAATTA
TTAATTAATAATTATGAATGAAACTGTTGAATTAGTTATTGTATTTAAAA
AGAAAATTGAAGAACTTCGCAAAGAAATTGAAGTCCTTGAAGTTCAATTA
CATGAAAAAGAAACAAAACTCAAAGAAGAGCAACATACACGTGACGAGTT
AGATAAGCAGGTAGTTCTTTTAAGTCGGAAAGTTGGTGTTCTTGAAAGTG
ATCTAGACGACAATGAAAAAAGATTACAAGAAGCTAAATTTAAGTTGGAA
GAAATCACATTTACTGCTGCAGAATGCGAACGAGCCCGTAGACAATTACA
AAGCAAACATGATGCTGATGATGAAAGAATTTATCATTTGGAAACATTGG
TTAAAGAGGCAACTGAACAAGCCGGAGAAGCAGAAGCTAGATACGAAGAA
GTTTCTAGGAAATTAATTGCTACAGAAAATGTATTAGAAAATACTGAAGA
TGAGTATGAGAAAACCGAAAAGAAATTGCGTGAAATTACTATGGAAATGA
CAAGTGTTTGTAATTCATTCAGAGTTTTAGAAATTAATGAGGCTCGAGCT
GCTGAAAGGGAACAGAAATTCGAAGTTGAAGTTAAGCATTTAAAAAAATT
ATTGCAAGACGCGGATAAACGGGCTAATGAAGCTGAAAATGAATTAAACC
AACGACAAATGATGCTGGACCAATTGGAAGAGGCTTTGGATAAAGAGAAA
AGAAACCATCAATTGTTAAGTAATGATTTGCAGAGAATGGTGGAAGAATT
TCAGCAAATGTAAACACAAATTAGGCATGAGTGATGATGAATCGGTTTAT
TGGTTAATTTACTTCCAATGATTACTTGTTGCTTATTTTCACAACGCTTT
AAATGCTTAAATTAATAAATTAATTTGATTTGTGAGAATATTCCAAGTTT
GGTTGATTATATACTATTTTGATTTTGTATATTTTCACTGTTGAATAGTT
TATTTTTCACTTTTCACATTTATTAATAAACTATTTGTTTCTAAAAAAAA
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protein sequence of SMED30014124-orf-1

>SMED30014124-orf-1 ID=SMED30014124-orf-1|Name=SMED30014124-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=250bp
MNETVELVIVFKKKIEELRKEIEVLEVQLHEKETKLKEEQHTRDELDKQV
VLLSRKVGVLESDLDDNEKRLQEAKFKLEEITFTAAECERARRQLQSKHD
ADDERIYHLETLVKEATEQAGEAEARYEEVSRKLIATENVLENTEDEYEK
TEKKLREITMEMTSVCNSFRVLEINEARAAEREQKFEVEVKHLKKLLQDA
DKRANEAENELNQRQMMLDQLEEALDKEKRNHQLLSNDLQRMVEEFQQM*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000026gut
PLANA:0000099neuron
PLANA:0000103central nervous system
PLANA:0000208testis
Vocabulary: INTERPRO
TermDefinition
IPR000533Tropomyosin
IPR012852CALCOCO1-like
Vocabulary: molecular function
TermDefinition
GO:0003779actin binding
GO:0008307structural constituent of muscle
GO:0051015actin filament binding
Vocabulary: cellular component
TermDefinition
GO:0005737cytoplasm
GO:0005862muscle thin filament tropomyosin
GO:0005884actin filament
Vocabulary: biological process
TermDefinition
GO:0006936muscle contraction
GO:0007015actin filament organization
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
NoneNo IPR availableCOILSCoilCoilcoord: 113..161
NoneNo IPR availableCOILSCoilCoilcoord: 8..56
NoneNo IPR availableCOILSCoilCoilcoord: 183..245
NoneNo IPR availableGENE3DG3DSA:1.20.5.340coord: 10..104
e-value: 2.7E-7
score: 32.5
coord: 125..224
e-value: 4.1E-7
score: 32.0
NoneNo IPR availablePANTHERPTHR19269TROPOMYOSINcoord: 9..247
NoneNo IPR availablePANTHERPTHR19269:SF45TROPOMYOSIN-1, ISOFORMS 33/34coord: 9..247
NoneNo IPR availableSUPERFAMILYSSF57997Tropomyosincoord: 11..249
IPR000533TropomyosinPRINTSPR00194TROPOMYOSINcoord: 110..138
score: 48.18
coord: 85..105
score: 33.93
coord: 196..221
score: 32.49
coord: 140..163
score: 31.47
coord: 49..66
score: 33.87
IPR000533TropomyosinPFAMPF00261Tropomyosincoord: 13..248
e-value: 1.7E-39
score: 135.6