Cytochrome P450 2K1-like protein

Query:  178 GLRPLQGPSGWPLVGNLFSIKEPL------W-----------------SIFYKH-AKTYGEIFKFKLGNRELVIINSSKILFKTLKDQGVNFSGRQQNDLIKYITHDCGIVFKE-KEWWSTQRSFALKVLRDFGLGKQRSIEIVNNECSILLQELEETSGKNICTKSCFPSVTVNIIAKLLMNMRFEKNSSEFFEF----RKIIEQTTHNRSFLV-ILFQIYTLPHFTIPFIARFSGLRNHIDAVHNFVINIINERKKTFSHENEGQDFIDMFLIEKHKLESENVKNHTFTDWQLIRMVVELFGAGFESTSTTLSWAMVLLARHTEIQDKVHQEIINLIGVDKIPDLNNKKFLHYTQAVMDEILRISTVAPLAVPHRVFNDAEVEGFYIPKDSTIFTNLYACHRDEKVWEKPFDFYPEHFLTKLDNGEMKYTPREELVPFSTGKRQCPGESLARLEYFVFLTSILQKFKIKFNKAIDDITYEKITRGTDGTVRAPLDVDLIFEMR 1602
            G+ P  GP+ WPLVGN   +  P       W                  +   H A+ YG IF F +G+  +V+++    + + L  Q   FS R +  LI  +T + G+VF      W  QR F+   LR FGLGK      +  E   +  E+++      C  S   +   NII  L    RF+  +SEF +      + +E   +++  LV I   +Y LP         F  LR     + +F+  II + +++   EN  QDFIDM+L+   + E +N  N +F +  L  ++ +LF AG ++T+ +L W ++ ++ + ++Q+KVH+EI  +IG ++ P L +K  + YT+A + E+ R++ V PLA+PH    +  ++G+ IPK + I  NL++ HRD  +WEKP DFYP  FL   D G++    +E  +PF  GKR C GE LA++E F+   S++Q F      A+ + + + +  G  G   AP   ++    R
Sbjct:   58 GIPP--GPTPWPLVGNFGHVLLPPFLRRRSWLSSRTRAAGIDPSVIGPQVLLAHLARVYGSIFSFFIGHYLVVVLSDFHSVREALVQQAEVFSDRPRVPLISIVTKEKGVVFAHYGPVWRQQRKFSHSTLRHFGLGKLSLEPKIIEEFKYVKAEMQKHGEDPFCPFSIISNAVSNIICSLCFGQRFDYTNSEFKKMLGFMSRGLEICLNSQVLLVNICPWLYYLP------FGPFKELRQIEKDITSFLKKIIKDHQESLDRENP-QDFIDMYLLHMEE-ERKNNSNSSFDEEYLFYIIGDLFIAGTDTTTNSLLWCLLYMSLNPDVQEKVHEEIERVIGANRAPSLTDKAQMPYTEATIMEVQRLTVVVPLAIPHMTSENTVLQGYTIPKGTLILPNLWSVHRDPAIWEKPEDFYPNRFLD--DQGQL--IKKETFIPFGIGKRVCMGEQLAKMELFLMFVSLMQSFAF----ALPEDSKKPLLTGRFGLTLAPHPFNITISRR 544          

Query:   94 LLNVLISIFLVIILYFLSRKFSTNPIPIGLRPLQGPSGWPLVGNLFSIK-EPLWSIFYKHAKTYGEIFKFKLGNRELVIINSSKILFKTLKDQGVNFSGRQQNDLIKYITHDCGIVFKEKEWWSTQRSFALKVLRDFGLGKQRSIEIVNNECSILLQELEETSGKNICTKSCFPSVTVNIIAKLLMNMRFEKNSSEFFEFRK----IIEQTTHNRSFLVILFQIYTLPHFTIPFIARFSGLRNHIDAVHNFVINIINERKKTFSHENEGQDFIDMFLIEKHKLESENVKNHTFTDWQLIRMVVELFGAGFESTSTTLSWAMVLLARHTEIQDKVHQEIINLIGVDKIPDLNNKKFLHYTQAVMDEILRISTVAPLAVPHRVFNDAEVEGFYIPKDSTIFTNLYACHRDEKVWEKPFDFYPEHFLTKLDNGEMKYTPREELVPFSTGKRQCPGESLARLEYFVFLTSILQKFKIKFNKAIDDI 1524
            L+ +L+ + +++++    ++ S   +P G  PL      P +GN   +  E +++   K ++ YG +F   LG R +V++     + + L DQ   FSGR +     ++    G+VF   E     R F++  LRDFG+GK+   E +  E   L+  L  T G NI           N+I+ ++   RF+    EF    +    I + T+ +   L  +F    + H   P    F  L+     + +F+   +   ++T    N  +DFID FLI     E E   N  F    L+   + LF  G E+ STTL +  +LL +H E++ KVH+EI  +IG ++ P   ++  + Y +AV+ EI R   V P+++  RV  D +   F++PK + ++  L +  RD   +  P DF P+HFL   + G+ K +  +  VPFS GKR C GE LAR+E F+F T+++Q F++K +++  DI
Sbjct:    8 LVALLVCLTVMVLMSVWQQRKSKGKLPPGPTPL------PFIGNYLQLNTEQMYNSLMKISERYGPVFTIHLGPRRVVVLCGHDAVREALVDQAEEFSGRGEQATFDWVFKGYGVVFSNGERAKQLRRFSIATLRDFGVGKRGIEERIQEEAGFLIDALRGTGGANIDPTFFLSRTVSNVISSIVFGDRFDYKDKEFLSLLRMMLGIFQFTSTSTGQLYEMFS-SVMKHLPGPQQQAFQLLQ----GLEDFIAKKVEHNQRTLD-PNSPRDFIDSFLIRMQ--EEEKNPNTEFYLKNLVMTTLNLFIGGTETVSTTLRYGFLLLMKHPEVEAKVHEEIDRVIGKNRQPKFEDRAKMPYMEAVIHEIQRFGDVIPMSLARRVKKDTKFRDFFLPKGTEVYPMLGSVLRDPSFFSNPQDFNPQHFLN--EKGQFKKS--DAFVPFSIGKRNCFGEGLARMELFLFFTTVMQNFRLKSSQSPKDI 471          

Query:  196 GPSGWPLVGNLFSIK-EPLWSIFYKHAKTYGEIFKFKLGNRELVIINSSKILFKTLKDQGVNFSGRQQNDLIKYITHDCGIVFKEKEWWSTQRSFALKVLRDFGLGKQRSIEIVNNECSILLQELEETSGKNICTKSCFPSVTVNIIAKLLMNMRFEKNSSEFFEF-RKIIEQTTHNRSFLVILFQIYT--LPHFTIPFIARFSGLRNHIDAVHNFVINIINERKKTFSHENEGQDFIDMFLIEKHKLESENVKNHTFTDWQLIRMVVELFGAGFESTSTTLSWAMVLLARHTEIQDKVHQEIINLIGVDKIPDLNNKKFLHYTQAVMDEILRISTVAPLAVPHRVFNDAEVEGFYIPKDSTIFTNLYACHRDEKVWEKPFDFYPEHFLTKLDNGEMKYTPREELVPFSTGKRQCPGESLARLEYFVFLTSILQKFKIKFNKAIDDI 1524
            GP+  P +GN   +  E +++   K ++ YG +F   LG R +V++     + + L DQ   FSGR +     ++    G+ F   E     R F++  LR FG+GK+   E +  E   L+  L  T G NI           N+I+ ++   RF+    EF    R ++       +    L+++++  + H   P    F  L+     + +F+   +   ++T    N  +DFID FLI     E E   N  F    L+   + LF AG E+ STTL +  +LL +H E++ KVH+EI  +IG ++ P   ++  + YT+AV+ EI R   + P+ + HRV  D +   F++PK + +F  L +  RD + +  P DF P+HFL K   G+ K +  +  VPFS GKR C GE LAR+E F+F T+I+Q F+ K  ++  DI
Sbjct:   36 GPTPLPFIGNYLQLNTEQMYNSLMKISERYGPVFTIHLGPRRVVVLCGHDAVKEALVDQAEEFSGRGEQATFDWLFKGYGVAFSNGERAKQLRRFSIATLRGFGVGKRGIEERIQEEAGFLIDALRGTHGANIDPTFFLSRTVSNVISSIVFGDRFDYEDKEFLSLLRMMLGSFQFTATSTGQLYEMFSSVMKHLPGPQQQAFKELQ----GLEDFIAKKVEHNQRTLD-PNSPRDFIDSFLIRMQ--EEEKNPNTEFYLKNLVMTTLNLFFAGTETVSTTLRYGFLLLMKHPEVEAKVHEEIDRVIGKNRQPKFEDRAKMPYTEAVIHEIQRFGDMLPMGLAHRVNKDTKFRDFFLPKGTEVFPMLGSVLRDPRFFSNPRDFNPQHFLDK--KGQFKKS--DAFVPFSIGKRYCFGEGLARMELFLFFTTIMQNFRFKSPQSPKDI 471          

Query:  112 SIFLVIILYFLSRKFSTNPIPIGLRPLQGPSGWPLVGNLFSIK-EPLWSIFYKHAKTYGEIFKFKLGNRELVIINSSKILFKTLKDQGVNFSGRQQNDLIKYITHDCGIVFKEKEWWSTQRSFALKVLRDFGLGKQRSIEIVNNECSILLQELEETSGKNICTKSCFPSVTVNIIAKLLMNMRFEKNSSEFFEFRKIIEQTTHNRSFLVILFQIYTLPHFTIPFIARF-----SGLRNHIDAVHNFVINIINERKKTFSHENEGQDFIDMFLIEKHKLESENVKNHTFTDWQLIRMVVELFGAGFESTSTTLSWAMVLLARHTEIQDKVHQEIINLIGVDKIPDLNNKKFLHYTQAVMDEILRISTVAPLAVPHRVFNDAEVEGFYIPKDSTIFTNLYACHRDEKVWEKPFDFYPEHFLTKLDNGEMKYTPREELVPFSTGKRQCPGESLARLEYFVFLTSILQKFKIK 1500
            ++ L  + + L+  F     P    P  GP   P +GN F +  E          K YG +F  +LG+   V+I    ++ + L     NF  R    + ++I    G++    + W  QR F L  LR+FGLGK+   E +  E   L + ++E +G+         +   NII  +    RFE   S F +  K++++ T+  +      Q+Y +     P+I +F       L ++   +  FV ++I++ +K ++   E +DFID +L E  K         +F +  LI   ++LF AG E+TSTTL WA++ +A + EIQ+KV  EI  +IG  + P    ++ + YT AV+ E+ R+  + PL VP  V  D  + G+++PK + I TNL A HRD   W  P  F P+HF   L+NG+ K   RE  +PFS GKR C GE LAR E F+F TS++QKF  +
Sbjct:   20 TLLLGTVAFLLAADFLKRRRPKNYPP--GPWRLPFLGNFFLVDFEQSHLEVQLFVKKYGNLFSLELGDISAVLITGLPLIKEALIHMDQNFGNRPVTPMREHIFKKNGLIMSSGQAWKEQRRFTLTALRNFGLGKKSLEERIQEEAQHLTEAIKEENGQPFDPHFKINNAVSNIICSITFGERFEYQDSWFQQLLKLLDEVTYLEASKTC--QLYNV----FPWIMKFLPGPHQTLFSNWKKLKLFVSHMIDKHRKDWN-PAETRDFIDAYLKEMSKHTGNPTS--SFHEENLICSTLDLFFAGTETTSTTLRWALLYMALYPEIQEKVQAEIDRVIGQGQQPSTAARESMPYTNAVIHEVQRMGNIIPLNVPREVTVDTTLAGYHLPKGTMILTNLTALHRDPTEWATPDTFNPDHF---LENGQFKK--REAFMPFSIGKRACLGEQLARTELFIFFTSLMQKFTFR 472          

Query:  196 GPSGWPLVGNLFSIK-EPLWSIFYKHAKTYGEIFKFKLGNRELVIINSSKILFKTLKDQGVNFSGRQQNDLIKYITHDCGIVFKEKEWWSTQRSFALKVLRDFGLGKQRSIEIVNNECSILLQELEETSGKNICTKSCFPSVTVNIIAKLLMNMRFEKNSSEFFEFRK----IIEQTTHNRSFLVILFQIYTLPHFTIPFIARFSGLRNHIDAVHNFVINIINERKKTFSHENEGQDFIDMFLIEKHKLESENVKNHTFTDWQLIRMVVELFGAGFESTSTTLSWAMVLLARHTEIQDKVHQEIINLIGVDKIPDLNNKKFLHYTQAVMDEILRISTVAPLAVPHRVFNDAEVEGFYIPKDSTIFTNLYACHRDEKVWEKPFDFYPEHFLTKLDNGEMKYTPREELVPFSTGKRQCPGESLARLEYFVFLTSILQKFKIKFNKAIDDI 1524
            GP+  P +GN   +  E +     K ++ YG +F   LG R +V++     + + L DQ   FSGR +     ++    G+ F   E       FA+  LRDFG+GK+   E +  E   L++ +  T G NI           N+I+ ++   RF+    EF         I + T+ +   L  +F    + H   P    F  L+     + +F+   +   ++T    N  QDFID FLI  H  E E   N  F    L+   + LF AG E+ STTL +  +LL +H E++ KVH+EI  +IG ++ P   ++  + Y +AV+ EI R   V P+++  RV  D +   F++PK + +F  L +  RD   +  P DF P+HFL   D G+ K +  +  VPFS GKR C GE LAR+E F+F T+++Q F++K +++  DI
Sbjct:   36 GPTPLPFIGNYLQLNTEHICDSIMKFSECYGPVFTIHLGPRRVVVLCGHDAVREALVDQAEEFSGRGEQATFDWVFKGYGVAFSNGERAKQLLRFAIATLRDFGVGKRGIEERIQEESGFLIEAIRSTHGANIDPTFFLSRTVSNVISSIVFGDRFDYEDKEFLSLLSMMLGIFQFTSTSTGQLYEMFS-SVMKHLPGPQQQAFKLLQ----GLEDFIAKKVEHNQRTLD-PNSPQDFIDSFLI--HMQEEEKNPNTEFYLKNLMMSTLNLFIAGTETVSTTLRYGFLLLMKHPEVEAKVHEEIDRVIGKNRQPKFEDRTKMPYMEAVIHEIQRFGDVIPMSLARRVKKDTKFRDFFLPKGTEVFPMLGSVLRDPSFFSNPQDFNPQHFLD--DKGQFKKS--DAFVPFSIGKRNCFGEGLARMELFLFFTTVMQNFRLKSSQSPKDI 471          

Query:   94 LLNVLISIFLVIILYFLSRKFSTNPIPIGLRPLQGPSGWPLVGNLFSIKEPL--WSIFYKHAKTYGEIFKFKLGNRELVIINSSKILFKTLKDQGVNFSGRQQNDLIKYI-THDCGIVFKEKEWWSTQRSFALKVLRDFGLGKQRSIEIVNNECSILLQELEETSGKNICTKSCFPSVTVNIIAKLLMNMRF-EKNSSEFFEFRKIIEQTTHNRSFLVILFQIYTLPHFTIPFIARF---SGLRNHIDAVHNFVINIINERKKTFSHE-------NEGQDFIDMFLIEKHKLESENVKNHTFTDWQLIRMVVELFGAGFESTSTTLSWAMVLLARHTEIQDKVHQEIINLIGVDKIPDLNNKKFLHYTQAVMDEILRISTVAPLAVPHRVFNDAEVEGFYIPKDSTIFTNLYACHRDEKVWEKPFDFYPEHFLTKLDNGEMKYTPREELVPFSTGKRQCPGESLARLEYFVFLTSILQKFKIKFNKAIDDITYEKITRGTDGTVRAPLDVDLIFEMRF 1605
            LL   ++I+ V  LY+  R F   P P+           P+ GNL SI  P   +  F +  K YG+++ F +GN   ++IN+   + +T       ++ +    ++      + GI+      W   R FAL  +RDFGLGK    E +  E   +   L+   G        F     N++ +LL   RF     +E+ E + II+          I  +++      IP  A+    S     I    +  +   N++ +   H        +E  DF++ FL E+ + ESE   + T+++ QL+ + ++L+ AG  +T+ T++WA+  +  H E+QDK+H+E+  +IG D++    +K  L Y  A ++E  R   + PL + H    D  ++GF IPK + +   +     +E+V+  P+ F P+ F+   +NG++K    +EL PFS GKR CPGE LAR+E F+F+ + L ++KI  +K         + +G+ G V AP     I   RF
Sbjct:    5 LLLTFLTIYFVYELYWKRRNFPPGPCPL-----------PVFGNLLSIANPPPGYKAFERWTKKYGDVYTFWIGNTPHIMINTWDKIKETFIRDADTYTNKVVLPMVTLSRGGEYGIIDSNGAMWREHRRFALSTMRDFGLGKNLMQENILMEVQDVFARLDAKLGSETDVPEVFDHAVANVVNQLLFGYRFMGPKENEYQELKHIIDSPAE------IFGKLHIFLAMNIPIFAKLLPESLYEGPIKTFRDTTLAFFNKQIEAHRHRIDFEDLNSESTDFVETFLKEQKRRESEG-DSETYSNIQLLNVCIDLWFAGLNTTTNTITWAISYVLHHPEVQDKIHEELDKVIGSDRLITTADKNDLPYFNASINESQRGINILPLNLQHATTRDTVIDGFKIPKGTGVVAQISTVMNNEEVFPDPYTFNPDRFID--ENGKLKKV--DELAPFSVGKRSCPGEGLARMELFLFIANFLNRYKIHPSKE----GLPSMAKGS-GPVVAPRLFTAILTRRF 495          

Query:  133 LYFLSRKFSTNPIPIGLRPLQGPSGWPLVGNLFSIKEPL--WSIFYKHAKTYGEIFKFKLGNRELVIINS-SKILFKTLKDQGVNFSGRQQNDLIKYITHDCGIVFKEKEWWSTQRSFALKVLRDFGLGKQRSIEIVNNECSILLQELEETSGKNICTKSCFPSVTVNIIAKLLMNMRF-EKNSSEFFEFRKIIEQTTHNRSFLVILFQIYTLPHF----TIPFIAR----------FSGLRNHIDAVHNFVINIINERKKTFSHENEGQDFIDMFLIEKHKLESENVKNHTFTDWQLIRMVVELFGAGFESTSTTLSWAMVLLARHTEIQDKVHQEIINLIGVDKIPDLNNKKFLHYTQAVMDEILRISTVAPLAVPHRVFNDAEVEGFYIPKDSTIFTNLYACHRDEKVWEKPFDFYPEHFLTKLDNGEMKYTPREELVPFSTGKRQCPGESLARLEYFVFLTSILQKFKI 1497
            LY+  R F   P P+           P+ GNL SI  P   +  F +  K YG+I+ F +GN   ++IN+  KI    ++D     +  +   L  +   + GI+      W   R FAL  +RDFGLGK    E +  E   +   L+   G        F     N++ +LL   RF     SE+ E ++IIE  T           ++  PH      IP IA+          F   R+   A  N  I    +        +E  DF++ FL E+ + ESE   + TF++ QL  + ++L+ AG  +T+ T++WA+  +  H E+QDKVH+E+  +IG D++    +K  L Y  A ++E  R   + PL + H    D  + GF IPK + +   +     +E+V+  P  F P+ F+   ++G++K    EEL PFS GKR CPGE LAR+E F+F+ + L ++KI
Sbjct:   18 LYWKRRNFPPGPCPL-----------PVFGNLLSIANPPPGYEAFERWTKKYGDIYTFWIGNTPHIMINTWDKIKETYIRDAETYTNKVRLPALDLFRGGEYGIIDSNGATWREHRRFALSTMRDFGLGKNLMQENILMEVQDVFARLDAKLGSETDIPEVFDHAVANVVNQLLFGYRFVGPKESEYQELKRIIEAPT----------DLFGKPHMFLAMNIPVIAKLMPEFMYEGPFKDFRDTAFAFFNKQIEAHRQEVDLNDLNSESTDFVETFLKEQKRRESEG-DSETFSNVQLSNVCMDLWFAGLNTTTNTITWAISYILHHPEVQDKVHEEMDKVIGSDRLITTADKNDLPYFNAFINEAQRGINIVPLNLQHATTRDTVINGFKIPKGTGVVAQISTVMNNEEVFPDPHTFNPDRFID--EHGKLKRV--EELAPFSVGKRSCPGEGLARMELFLFIANFLNRYKI 464          

Query:  118 FLVIILYFLSRKFSTNPIPIGLRPLQGPSGWPLVGNLFSIKEPL--WSIFYKHAKTYGEIFKFKLGNRELVIINSSKILFKTLKDQGVNFSGRQQNDLIK-YITHDCGIVFKEKEWWSTQRSFALKVLRDFGLGKQRSIEIVNNECSILLQELEETSGKNICTKSCFPSVTVNIIAKLLMNMRFEKNSSE-------FFEFRKIIEQTTHNRSFLVILFQIYTLPHFTIPFIARFSGLRNHIDAVHNFVINIINERKKTFSHENEGQDFIDMFLIEKHKLESENVKNHTFTDWQLIRMVVELFGAGFESTSTTLSWAMVLLARHTEIQDKVHQEIINLIGVDKIPDLNNKKFLHYTQAVMDEILRISTVAPLAVPHRVFNDAEVEGFYIPKDSTIFTNLYACHRDEKVWEKPFDFYPEHFLTKLDNGEMKYTPREELVPFSTGKRQCPGESLARLEYFVFLTSILQKFKI 1497
            FL   LY+  R +   P P+           PL+GNL S++ P   +  F +    YG+I+ F LG R  ++++S + L +T    G  ++ ++     + +     G+V     +W   R FA+   RDFGLGK R  + +  E   +    ++T G+ +     F     N+I ++L   RF++  ++       FF F      +   R    + +  Y +P  TI  + RF   +        F   I N +K+      E  D+++ FL E+ K E+      +F+  QL  M ++L+ A   +TS T++W       + + Q K+H+E+  +IG ++  +  +K  L YT A ++EI R + + PL + H    D  ++G+ IPK + +   +     DE V+ +P+ F PE FL   D+G++K    E+LVPFS GKRQC GE LAR+E F+F+ +   ++++
Sbjct:   13 FLFHHLYWKRRNWPAGPTPL-----------PLIGNLLSLRNPAPGYKAFARWTAKYGDIYTFWLGTRPYILVSSYEALKETFIKDGETYADKKPMAFQESFRGGSYGVVETNGPFWREHRRFAIHQFRDFGLGKDRMEQRIMLEVEDIFNNCDKTIGEGVDLTDIFDRAVGNVINQMLFGYRFDETRADEFRTIRAFFNFNSGEFASFSMRVQFFLPWMGYIMPGPTI--LDRFKKYQKGFTEF--FGTQIENHKKEIDFELEENSDYVEAFLKEQRKREASG-DFESFSTKQLSNMCLDLWFAALMTTSNTMTWCFAYTLNYLDAQQKLHEELDRVIGSERHINTADKPNLPYTNAYINEIQRTANLVPLNLLHMTTRDTVLKGYNIPKGTGVVAQISTVMYDENVFPEPYIFKPERFLD--DDGKLKKV--EQLVPFSVGKRQCLGEGLARMELFLFIANFFNRYRV 462          

Query:   94 LLNVLISIFLVIILYFLSRKFSTNPIPIGLRPLQGPSGWPLVGNLFS--IKEPLWSIFYKHAKTYGEIFKFKLGNRELVIINSSKILFKTLKDQGVNFSGRQQNDLIKYITHDC-GIVFKEKEWWSTQRSFALKVLRDFGLGKQRSIEIVNNECSILLQELEETSGKNICTKSCFPSVTVNIIAKLLMNMRF-EKNSSEFFEFRKIIEQTTHNRSFLVILFQIYTLPHFTIPFIARF---SGLRNHIDAVHN-----FVINIINERKKTFSHENEGQDFIDMFLIEKHKLESENVKNHTFTDWQLIRMVVELFGAGFESTSTTLSWAMVLLARHTEIQDKVHQEIINLIGVDKIPDLNNKKFLHYTQAVMDEILRISTVAPLAVPHRVFNDAEVEGFYIPKDSTIFTNLYACHRDEKVWEKPFDFYPEHFLTKLDNGEMKYTPREELVPFSTGKRQCPGESLARLEYFVFLTSILQKFKI 1497
            LL+  + +FL   LY+  R     P P+           P +GN  +  +++P +  F +  K +G ++ F +GN   VII S  +L +T    G  +  +      + +     GIV      WST R FAL  LRDFGLGK    E +  E   + ++ +   GK    +    +   N+I + +   RF E N  EF   R ++E      + + +  + +      +P I +F     L   +D   N     F   I N RKK      E QD+ + +L E+ K E+   +   F++ Q     ++L+ AG  +T+TT++W +  +  H ++  K+++E   ++G D++  + +K  L Y  AV++E  R + + P+ + H    D  + G+ + K + +   +     DEK++ +P+ F P+ F+   +NG  K    E+L+PFS GKRQCPGE LAR+E F+FL +   ++KI
Sbjct:    5 LLSAAVCLFLFHELYWKRRSLPPGPTPL-----------PFMGNTLAMLLEKPGYECFRRWTKQFGGVYTFWMGNIPYVIIGSYDLLKETFVRDGDTYKDKYPQPFNEKLRGGMYGIVESNGHMWSTHRRFALSTLRDFGLGKDLMQEKILIEVEDIFRKYDAQLGKEQDIQVVLNNAIANVINQTIFGYRFDETNQEEFERMRHLVEYQEKQFATVKVYVEAF------VPTIGKFLPGKSLDQLLDDWRNSFYTFFDTQIENHRKKIDFDSEESQDYAEAYLKEQKKQEALG-EFELFSNTQFSNTCLDLWLAGVSTTNTTVNWTICYVLNHPDVLQKMNEEFDQVVGSDRLVTMGDKNNLPYFNAVLNESQRCANIVPINLFHATTKDTVINGYPVKKGTGVIAQISTVMLDEKIFPEPYKFNPDRFID--ENG--KPIKIEQLIPFSIGKRQCPGEGLARMEIFLFLANFFNRYKI 462          

Query:  103 VLISIFLVIILYFLSR-KFSTNPIPIGLRPLQGPSGWPLVGNLFSIK--EPLWSIFYKHAKTYGEIFKFKLGNRELVIINSSKILFKTLKDQGVNFSGRQQNDLIK-YITHDCGIVFKEKEWWSTQRSFALKVLRDFGLGKQRSIEIVNNECSILLQELEETSGKNICTKSCFPSVTVNIIAKLLMNMRFEKNS-SEFFEFRKIIEQTTHNRSFLVILFQIYTLPHFT--IPFIARFSGLRNHIDAVHNFVINIINERKKTFSHEN-EGQDFIDMFLIEKHKLESENVKNHTFTDWQLIRMVVELFGAGFESTSTTLSWAMVLLARHTEIQDKVHQEIINLIGVDKIPDLNNKKFLHYTQAVMDEILRISTVAPLAVPHRVFNDAEVEGFYIPKDSTIFTNLYACHRDEKVWEKPFDFYPEHFLTKLDNGEMKYTPREELVPFSTGKRQCPGESLARLEYFVFLTSILQKFKI--KFNKAIDDITYEK 1536
            +L+ IF  I LYF     +    +P G RPL      P +GNL S+K  +P +  F    K YG IF F + N+  VII S + + +T    G  +  +Q     K  +  + G++      W   R F L  LRD GLGK    E +  E   L +EL+   G+ I           N+I   L N RF+ +   EF   + +I+   +  S    L Q Y +P  +  +P       +R   + + +F  + I+E +     +N E  DF++ +L E+ K E E+    TF + QL  M+ +L+ AG  +T+ T++W +     + E+Q K+ +E+  +IG D++    +K  L Y QA + E  R + + PL + H    D  ++GF I K + +   +     DEKV+ +P+ F PE F   ++NG+ K    +E++PFS GKRQC GE LAR+E F+F  +I  ++ +   F+ ++ D+   K
Sbjct:    2 LLLLIFSSIFLYFFYHFHWKRRNLPPGPRPL------PFLGNLLSLKTLKPGYEAFSNWKKEYGPIFTFWMANKPFVIIASYEKMKETFVKDGDTYVDKQLTHTEKERLGENYGVLDTNGHMWKEHRRFTLTQLRDLGLGKDLMQEKILMEVEELFKELDAHGGEEIDLPKLIDRSVGNVINLTLFNKRFDMDKRDEFAHLKSLIDGMRNVTSQFRYLIQ-YLVPWTSTVLPGPTLSEKVRAKREELDDFFYSQIDEHRNEIDFDNTENLDFVEAYLKEQKKRE-EDGDFKTFCNKQLCAMLFDLWIAGLMTTTMTMTWGLSYYLYNPEVQRKIREELDKVIGNDRLISTADKNDLPYLQAFVTETQRTANIIPLNLIHMTTRDTVIDGFPIQKGTGVIAQISTVMYDEKVFPEPYKFKPERF---IENGKFKKV--DEVIPFSIGKRQCLGEGLARIELFLFFANIFNRYDVMPDFSGSLPDLDKSK 476          

Query:  196 GPSGWPLVGNLFSIKEPLWSIFYKHAKTYGEIFKFKLGNRELVIINSSKILFKTLKDQGVNFSGRQQNDLIKYITHDCGIVFKEKEWWSTQRSFALKVLRDFGL-----GKQRSIEIVNNECSILLQELEETSGKNICTKSCFPSVTVNIIAKLLMNMRFEKNSSEFFEFRKIIEQTTHNRSFLVILFQIYTLPHF-TIPFIARFSGLRNHIDA----VHNFVINIINERKKTFSHENEGQDFIDMFLIEKHKLESENVKNHTFT----DWQLIRMVVELFGAGFESTSTTLSWAMVLLARHTEIQDKVHQEIINLIGVDKIPDLNNKKFLHYTQAVMDEILRISTVAPLAVPHRVFNDAEVEGFYIPKDSTIFTNLYACHRDEKVWEKPFDFYPEHFLTKLDNGEMKYTPREELVPFSTGKRQCPGESLARLEYFVFLTSILQKFKIKFNKA 1512
            GP G P++G L  +     + F + AK YG +F  +LG++  V+++  K++ +  + +   F+GR     ++ + +  GI+    + W  QR F    LR FG+     GKQ+  + +  E    +  L  + G+ +           N+I  L+M+ RF  +  +F  F  +IE+       + +  +I+T+ +  T+      S  +N I      +  F  ++I++ K++F   N  +D +D +L E  K ++E      F     + QL++++++LF AG E+  TTL W  V + R+ +   +V  E+  ++G  ++P + + ++L  T++ + E +R S++ PLA  H    D E+ G+ IP  S +   + + H D  +WEKP +F P  F+    + E K    E  +PF  G+R C G+ LAR+E F+F  S +  F I   + 
Sbjct:   56 GPWGLPVIGYLLFMGSEKHTRFMELAKQYGSLFSTRLGSQLTVVMSDYKMIRECFRRE--EFTGRPDTPFMQTL-NGYGIINSTGKLWKDQRRFLHDKLRQFGMTYMGNGKQQMQKRIMTEVHEFIGHLHASDGQPVDMSPVISVAVSNVICSLMMSTRFSIDDPKFRRFNFLIEEG------MRLFGEIHTVDYIPTMQCFPSISTAKNKIAQNRAEMQRFYQDVIDDHKRSFD-PNNIRDLVDFYLCEIEKAKAEGTDAELFDGKNHEEQLVQVIIDLFSAGMETIKTTLLWINVFMLRNPKEMRRVQDELDQVVGRHRLPTIEDLQYLPITESTILESMRRSSIVPLATTHSPTRDVELNGYTIPAGSHVIPLINSVHMDPNLWEKPEEFRPSRFI----DTEGKVRKPEYFIPFGVGRRMCLGDVLARMELFLFFASFMHCFDIALPEG 494          

Query:  196 GPSGWPLVGNLFSIKEPLWSIFYKHAKTYGEIFKFKLGNRELVIINSSKILFKTLKDQGVNFSGRQQNDLIKYITHDCGIVFKEKEWWSTQRSFALKVLRDFGL-----GKQRSIEIVNNECSILLQELEETSGKNICTKSCFPSVTVNIIAKLLMNMRFEKNSSEFFEFRKIIEQTTHNRSFLVILFQIYTLPHF-TIPFIARFSGLRNHIDA----VHNFVINIINERKKTFSHENEGQDFIDMFLIEKHKLESENVKNHTFT----DWQLIRMVVELFGAGFESTSTTLSWAMVLLARHTEIQDKVHQEIINLIGVDKIPDLNNKKFLHYTQAVMDEILRISTVAPLAVPHRVFNDAEVEGFYIPKDSTIFTNLYACHRDEKVWEKPFDFYPEHFLTKLDNGEMKYTPREELVPFSTGKRQCPGESLARLEYFVFLTSILQKFKIKFNKA 1512
            GP G P++G L  +     + F + AK YG +F  +LG++  V+++  K++ +  + +   F+GR     ++ + +  GI+    + W  QR F    LR FG+     GKQ+  + +  E    +  L  + G+ +           N+I  L+M+ RF  +  +F  F  +IE+       + +  +I+T+ +  T+      S  +N I      +  F  ++I++ K++F   N  +D +D +L E  K ++E      F     + QL++++++LF AG E+  TTL W  V + R+ +   +V  E+  ++G  ++P + + ++L  T++ + E +R S++ PLA  H    D E+ G+ IP  S +   + + H D  +WEKP +F P  F+    + E K    E  +PF  G+R C G+ LAR+E F+F  S +  F I   + 
Sbjct:   56 GPWGLPVIGYLLFMGSEKHTRFMELAKQYGSLFSTRLGSQLTVVMSDYKMIRECFRRE--EFTGRPDTPFMQTL-NGYGIINSTGKLWKDQRRFLHDKLRQFGMTYMGNGKQQMQKRIMTEVHEFIGHLHASDGQPVDMSPVISVAVSNVICSLMMSTRFSIDDPKFRRFNFLIEEG------MRLFGEIHTVDYIPTMQCFPSISTAKNKIAQNRAEMQRFYQDVIDDHKRSFD-PNNIRDLVDFYLCEIEKAKAEGTDAELFDGKNHEEQLVQVIIDLFSAGMETIKTTLLWINVFMLRNPKEMRRVQDELDQVVGRHRLPTIEDLQYLPITESTILESMRRSSIVPLATTHSPTRDVELNGYTIPAGSHVIPLINSVHMDPNLWEKPEEFRPSRFI----DTEGKVRKPEYFIPFGVGRRMCLGDVLARMELFLFFASFMHCFDIALPEG 494          

Query:  196 GPSGWPLVGNLFSIKE---------PLWSIFYK-HAKTYGEIFKFKLGNRELVIINSSKILFKTLKDQGVNFSGRQQNDLIKYITHDC--GIVFKEKEWWSTQRSFALKVLRDFGLGKQRSIEIVNNECSILLQELEE----TSGKN--ICTKSCFPSVTVNIIAKLLMNMRFEKNSSEFFEFRKIIEQTTHNRSFLVILFQIYTLPHFTIPFIARFSGLRNHIDAVHNFVINIINERKKTFSHENEGQDFIDMFLIEKHKLESENVKNHTFTDWQLIRMVVELFGAGFESTSTTLSWAMVLLARHTEIQDKVHQEIINLIGVDKIPDLN-NKKFLHYTQAVMDEILRISTVAPLAVPHRVFNDAEVEGFYIPKDSTIFTNLYACHRDEKV----WEKPFDFYPEHFLTKLDNGEMKYTPREELVPFSTGKRQCPGESLARLEYFVFLTSILQKFKIKFNKAIDDITYEKIT-RGTDGTVRAPLDVDLI 1590
            GP+ +P+VG+   + +          +  +F + +   YG  +  K+G  ++VI  ++  + + + ++ ++  GR      +  T +   G++  + E W  QR F L+ L++FG  +   ++IV+NE + LLQ+L++    + GK   I          +N +  +L   R+E  S E  +  +   +   N   +  LF  + L  F  P  + ++G      +++ F+   I   + T+ + +E +D +D +L  +   +  N +   F+D  L+ + +++F AG E+T+ +L +  + L    EIQ++  QEI  ++G+++IP+ + ++  L Y +A+  E +R+  +    +PHR   D  + G+ IPKD+ +     AC R   +    +  P  F P+ +L    +G +K    E   PF  G+ +C G+ L R   F+F T++LQ FK+    AI     E++   G    V+ P D+ L+
Sbjct:   30 GPAWYPIVGSALQVSQLRCRLGMFCKVIDVFARQYVNPYG-FYGLKIGKDKVVIAYTNDAISEMMTNEDID--GRPDGIFYRLRTFNSRLGVLLTDGEMWVEQRRFILRHLKNFGFARSGMMDIVHNEATCLLQDLKDKVLKSGGKQTRIEMHDLTSVYVLNTLWCMLSGRRYEPGSPEITQLLETFFELFKNIDMVGALFSHFPLLRFIAPNFSGYNGFVESHRSLYTFMSKEIELHRLTYKNYDEPRDLMDSYLRAQ---DEGNDEKGMFSDQSLLAICLDMFLAGSETTNKSLGFCFMHLVLQPEIQERAFQEIKEVVGLERIPEWSRDRTKLPYCEAITLEAVRMFMLHTFGIPHRAVCDTRLSGYEIPKDTMVI----ACFRGMLINPVDFPDPESFNPDRYLF---DGHLKLP--EAFNPFGFGRHRCMGDLLGRQNLFMFTTTVLQNFKM---VAIPGQVPEEVPLEGATAAVK-PYDIMLV 499          

Query:  196 GPSGWPLVGNLFSIKE---------PLWSIFYK-HAKTYGEIFKFKLGNRELVIINSSKILFKTLKDQGVNFSGRQQNDLIKYITHDC--GIVFKEKEWWSTQRSFALKVLRDFGLGKQRSIEIVNNECSILLQELEE----TSGKN--ICTKSCFPSVTVNIIAKLLMNMRFEKNSSEFFEFRKIIEQTTHNRSFLVILFQIYTLPHFTIPFIARFSGLRNHIDAVHNFVINIINERKKTFSHENEGQDFIDMFLIEKHKLESENVKNHTFTDWQLIRMVVELFGAGFESTSTTLSWAMVLLARHTEIQDKVHQEIINLIGVDKIPDLN-NKKFLHYTQAVMDEILRISTVAPLAVPHRVFNDAEVEGFYIPKDSTIFTNLYACHRDEKV----WEKPFDFYPEHFLTKLDNGEMKYTPREELVPFSTGKRQCPGESLARLEYFVFLTSILQKFKIKFNKAIDDITYEKIT-RGTDGTVRAPLDVDLI 1590
            GP+ +P+VG+   + +          +  +F + +   YG  +  K+G  ++VI  ++  + + + ++ ++  GR      +  T +   G++  + E W  QR F L+ L++FG  +   ++IV+NE + LLQ+L++    + GK   I          +N +  +L   R+E  S E  +  +   +   N   +  LF  + L  F  P  + ++G      +++ F+   I   + T+ + +E +D +D +L  +   +  N +   F+D  L+ + +++F AG E+T+ +L +  + L    EIQ++  QEI  ++G+++IP+ + ++  L Y +A+  E +R+  +    +PHR   D  + G+ IPKD+ +     AC R   +    +  P  F P+ +L    +G +K    E   PF  G+ +C G+ L R   F+F T++LQ FK+    AI     E++   G    V+ P D+ L+
Sbjct:   30 GPAWYPIVGSALQVSQLRCRLGMFCKVIDVFARQYVNPYG-FYGLKIGKDKVVIAYTNDAISEMMTNEDID--GRPDGIFYRLRTFNSRLGVLLTDGEMWVEQRRFILRHLKNFGFARSGMMDIVHNEATCLLQDLKDKVLKSGGKQTRIEMHDLTSVYVLNTLWCMLSGRRYEPGSPEITQLLETFFELFKNIDMVGALFSHFPLLRFIAPNFSGYNGFVESHRSLYTFMSKEIELHRLTYKNYDEPRDLMDSYLRAQ---DEGNDEKGMFSDQSLLAICLDMFLAGSETTNKSLGFCFMHLVLQPEIQERAFQEIKEVVGLERIPEWSRDRTKLPYCEAITLEAVRMFMLHTFGIPHRAVCDTRLSGYEIPKDTMVI----ACFRGMLINPVDFPDPESFNPDRYLF---DGHLKLP--EAFNPFGFGRHRCMGDLLGRQNLFMFTTTVLQNFKM---VAIPGQVPEEVPLEGATAAVK-PYDIMLV 499          

Query:   97 LNVLISIFLVIILYFLSRKFSTNPIPIGLRPLQGPSGWPLVGNLFSIKEPLWSIFYKH------AKTY-GEIFKFKLGNRELVIINSSKILFKTLKDQGVNFSGRQQNDLIKYITHDC--GIVFKEKEWWSTQRSFALKVLRDFGLGKQRSIEIVNNECSILLQELEETSGKNICTKSCFPSVTVNIIAKLLMNMRFEKNSSEFFEFRKIIEQTTHNRSFLVI----LFQIYTLPHFTIPFIARFSGLRNHIDAVHNFVINIINERKKTFSHENEG--QDFIDMFLIEKHKLESENVKNHTFTDWQLIRMVVELFGAGFESTSTTLSWAMVLLARHTEIQDKVHQEI---INLIGVDKIPDLNNKKFLHYTQAVMDEILRISTVAPLAVPHRVFNDAEVEGFYIPKDSTIFTNLYACHRDEKVWEKPFDFYPEHFLTKLDNGEMKYTPREELVPFSTGKRQCPGESLARLEYFVFLTSILQKFKI 1497
            ++ LI +  ++I + +    S+   P    P  GP   P +GN    ++   ++  +H      AK +  ++   KLG RE V++     + K ++ Q V F GR  N  ++  T     GI   + + W   R FA+K +R+ G G+ +    +  E   LL +LE T  + I   +      +N++  L+   R  +   E    R++++          I    L Q   L H   P    ++ ++     ++ F ++ I E ++  + +      D I  +L ++ K  S   ++ TF + QL+  +++ F AG ++TS T++ A+++LA   ++Q+K+  ++   +     D  P L+ ++   Y  A + E+ R   + P+  P R     ++ G+ IPK++TI  +L + H D++ W+ P +F PE F+    +   K    E  +PF  G+R+C G++LAR   F FL  I+Q F +
Sbjct:    1 MSALIFLCAILIGFVIYSLISSARRPKNFPP--GPRFVPWLGNTLQFRKEASAVGGQHILFERWAKDFRSDLVGLKLG-REYVVVALGHEMVKEVQLQEV-FEGRPDNFFLRLRTMGTRKGITCTDGQLWYEHRHFAMKQMRNVGYGRSQMEHHIELEAEELLGQLERTEEQPIEPVTWLAQSVLNVLWCLIAGKRIARQ--EDGTLRRLLDLMNRRSKLFDICGGLLAQFPWLRHVA-PDRTGYNLIQQLNTELYGFFMDTIEEHRRQLAKDPSPAESDLIYAYL-QEMKDRSAGGESSTFNETQLVMTILDFFIAGSQTTSNTINLALMVLAMRPDVQEKLFSQVTASVAAASTDAFPHLSRREAFDYMDAFIMEVQRFFHITPITGPRRALWATKLGGYDIPKNATILISLRSVHLDKEHWKDPLEFRPERFI----DSAGKCFKDEYFMPFGMGRRRCLGDALARACIFSFLVRIVQHFSV 473          

Query:  217 VGNLFSI-KEPLWSIFYKHAKTYGEIFKFKLGNRELVIINSSKILFKTLKDQGVNFSGRQQNDLIKYITHDCGIVFKEKEWWSTQRSFALKVLRDFGLGKQRSIEIVNNECSILLQELEETSGKNICTKSCFPSVTVNIIAKLLMNMRFEKNSSEFFEFRKIIEQTTHNRSFLVILFQIYTL-PHFTIPFIARFSGLRNHIDAVHNFVINIINERKKTFSHENEGQDFIDMFLI----EKHKLESENVKNHTFTDWQLIRMVVELFGAGFESTSTTLSWAMVLLARHTEIQDKVHQEIINLIGVDKIPDLNNKKFLHYTQAVMDEILRISTVAPLAVPHRVFNDAEVEGFYIPKDSTIFTNLYACHRDEKVWEKPFDFYPEHFLTKLDNGEMKYTPREELVPFSTGKRQCPGESLARLEYFVFLTSILQKFKIKFNKAIDDI 1524
            +GNL ++ K   +  F K  KTYG +    LG + +V++   + + + L DQ  +F+ R     +  I    G+     E W   R F L  LRDFG+G++R  + +  E   LL+  EET  K +     F     N+I  L+   RF+     F +  +II +    R       Q+Y + P     F +R   +   ++ +  F+ N + E ++     ++  DFID FLI    EK KL++E  K++      L+  V+ LF AG E+TSTTL +A++LL +H +IQ+++ +EI  +IG ++IP + ++K L +T AV+ E+ R   + PL++PH    D    G+ IPKD+ I   L++  RDE  WE P+ F PEHFL    NG  K  P    +PFS GKR C GESLAR+E F+F+ S+LQKF        D I
Sbjct:   40 IGNLLTLDKSAPFKSFMKWRKTYGSVMTVHLGPQRMVVLVGYETVKEALVDQADDFAPRAPIPFMNRIVKGYGLAISNGERWRQLRRFTLTTLRDFGMGRKRMEQWIQEESRYLLKSFEETKSKPVDPTFFFSRTVSNVICSLVFGQRFDYEDKNFLQLLQIISKLL--RFLSSPWGQLYNIFPQVMESFSSRHHAILKDVENIRTFIRNKVKEHEQRLDF-SDPSDFIDCFLIRLTQEKDKLDTEFHKDN------LMATVLNLFVAGTETTSTTLRYALMLLIKHPQIQEQMQREIDRVIGQNRIPTMEDRKSLPFTDAVIHEVQRYMDIVPLSLPHYAMKDITFRGYKIPKDTVIIPMLHSVLRDEGHWETPWTFNPEHFLDS--NGNFKKNP--AFMPFSAGKRVCVGESLARMEIFLFIVSLLQKFSFSSPNGPDSI 468          

Query:  217 VGNLFSI-KEPLWSIFYKHAKTYGEIFKFKLGNRELVIINSSKILFKTLKDQGVNFSGRQQNDLIKYITHDCGIVFKEKEWWSTQRSFALKVLRDFGLGKQRSIEIVNNECSILLQELEETSGKNICTKSCFPSVTVNIIAKLLMNMRFEKNSSEFFEFRKIIEQTTHNRSFLVILFQIYTL-PHFTIPFIARFSGLRNHIDAVHNFVINIINERKKTFSHENEGQDFIDMFLI----EKHKLESENVKNHTFTDWQLIRMVVELFGAGFESTSTTLSWAMVLLARHTEIQDKVHQEIINLIGVDKIPDLNNKKFLHYTQAVMDEILRISTVAPLAVPHRVFNDAEVEGFYIPKDSTIFTNLYACHRDEKVWEKPFDFYPEHFLTKLDNGEMKYTPREELVPFSTGKRQCPGESLARLEYFVFLTSILQKFKIKFNKAIDDI 1524
            +GNL ++ K   +  F K  KTYG +    LG + +V++   + + + L DQ  +F+ R     +  I    G+     E W   R F L  LRDFG+G++R  + +  E   LL+  EET  K +     F     N+I  L+   RF+     F +  +II +    R       Q+Y + P     F +R   +   ++ +  F+ N + E ++     ++  DFID FLI    EK KL++E  K++      L+  V+ LF AG E+TSTTL +A++LL +H +IQ+++ +EI  +IG ++IP + ++K L +T AV+ E+ R   + PL++PH    D    G+ IPKD+ I   L++  RDE  WE P+ F PEHFL    NG  K  P    +PFS GKR C GESLA +E F+F  S+LQKF        D I
Sbjct:   40 IGNLLTLDKSAPFKSFMKWRKTYGSVMTVHLGPQRMVVLVGYETVKEALVDQADDFAPRAPIPFMNRIVKGYGLAISNGERWRQLRRFTLTTLRDFGMGRKRMEQWIQEESRYLLKSFEETKSKPVDPTFFFSRTVSNVICSLVFGQRFDYEDKNFLQLLQIISKLL--RFLSSPWGQLYNIFPQVMESFSSRHHAILKDVENIRTFIRNKVKEHEQRLDF-SDPSDFIDCFLIRLTQEKDKLDTEFHKDN------LMATVLNLFVAGTETTSTTLRYALMLLIKHPQIQEQMQREIDRVIGQNRIPTMEDRKSLPFTDAVIHEVQRYMDIVPLSLPHYAMKDITFRGYKIPKDTVIIPMLHSVLRDEGQWETPWTFNPEHFLDS--NGNFKKNP--AFMPFSAGKRSCVGESLASMELFLFTVSLLQKFTFSSPNGPDGI 468          

Query:  196 GPSGWPLVGNLFSIK--EPLWSIFYKHAKTYGEIFKFKLGNRELVIINSSKILFKTLKDQGVNFSGRQQNDLIKYITHDCGIVFKEKEWWSTQRSFALKVLRDFGLGKQRSIEIVNNECSILLQELEETSGKNICTKSCFPSVTVNIIAKLLMNMRFEKNSSEFFEF-RKIIEQTTHNRSFLVILFQIYTLPHFTIPFIARFSGLRNHIDAVHNFVINIINERKKTFS-----HENEGQDFIDMFLIEKHKLESENVKNHTFTDWQLIRMVVELFGAGFESTSTTLSWAMVLLARHTEIQDKVHQEIINLIGVDKIPDLNNKKFLHYTQAVMDEILRISTVAPLAVPHRVFNDAEVEGFYIPKDSTIFTNLYACHRDEKVWEKPFDFYPEHFLTKLDNGEMKYTPREELVPFSTGKRQCPGESLARLEYFVFLTSILQKFK 1494
            GP   PLVGNL ++    P +  F+K +KTYG +F+  LG  + V++   K + + L +    F  R+       +  + GI+F   E W   R FAL  LRDFG+GK+ S E +  E   L  E ++  GK   T         NII+ ++   RFE    +F E   +  E      S  + L+ I+       P++  F  L+N    V N + + +   K   +     + N+ + F+D FLI K   E    K+  F +  L+  V  LF AG ++T TTL W ++L+A++  IQD+V +EI  +IG  + P + ++K L YT AV+ EI R++ + PL++PHR  +D    G++I K +T+   L +  +DE  WEKP  FYPEHFL +    + ++  R+  +PFS G+R C GESLAR+E F+F TS+LQ ++
Sbjct:   47 GPKPLPLVGNLLTLDLTRP-FDTFFKLSKTYGNVFQVYLGPEKAVVLVGYKTVKEALVNYAEEFGDREIGPGFSIMNDEHGILFSNGENWKEMRRFALSNLRDFGMGKRGSEEKIIEEIHHLKGEFDKFEGKPFDTTQPVNYAVSNIISSIVYGSRFEYTDPQFTEMVDRANENVRVGGSISMWLYDIF-------PWLGPF--LKNKRIIVENIIQSRVQMTKLITALLETLNPNDPRGFVDSFLIRKLSDEKSGKKDSYFHEENLMMTVTNLFIAGTDTTGTTLRWGLMLMAKYPHIQDRVQEEIDRVIG-GRQPVVEDRKKLPYTDAVIHEIQRLANIVPLSLPHRTTSDITFNGYFIKKGTTVVPLLTSVLKDESEWEKPNSFYPEHFLDE----KGQFVRRDAFMPFSAGRRVCLGESLARMELFLFFTSLLQSYR 472          

Query:  196 GPSGWPLVGNLFSIK-EPLWSIFYKHAKTYGEIFKFKLGNRELVIINSSKILFKTLKDQGVN----FSGRQQNDLIKYITHDCGIVFKEKEWWSTQRSFALKVLRDFGLGKQRSIEIVNNECSILLQELEETSGKNICTKSCFPSVTVNIIAKLLMNMRFEKNSSEFFEF-RKIIEQTTHNRSFLVILFQIYTLPHFTIPFIARFSGLRNHIDAVHNFVINIINERKKTFS------HENEGQDFIDMFLIEKHKLESENVKNHTFTDWQLIRMVVELFGAGFESTSTTLSWAMVLLARHTEIQDKVHQEIINLIGVDKIPDLNNKKFLHYTQAVMDEILRISTVAPLAVPHRVFNDAEVEGFYIPKDSTIFTNLYACHRDEKVWEKPFDFYPEHFLTKLDNGEMKYTPREELVPFSTGKRQCPGESLARLEYFVFLTSILQKFK 1494
            GP   PLVGNL ++     +  F++ +KTYG IF+  LG+R+ V++    + +KT+K+  VN    F  R+     K    + GI+F   E W   R FAL  LRDFG+GK+ S E +  E   L  E ++  GK   T         NII+ ++   RFE     F E   +  E      SF ++++ I+       P++  F  L+N    V N   N   E+KK  +      + ++ + F+D FLI K   E    K+  F +  L+  V  LF AG ++T TTL W ++L+A++  IQD+V +EI  +IG  + P ++++K L YT AV+ EI R++ + PL++PHR  +D    G++I K +T+   L +  +DE  WEKP  FYPEHFL +    + ++  R+  +PFS G+R C GESLAR+E F+F TS+LQ ++
Sbjct:   68 GPKPLPLVGNLLTLDLTRSFDTFFELSKTYGNIFQVFLGHRKTVVL----VGYKTVKEALVNYAEVFGDREIGPGFKLKDEEHGILFSNGENWKEMRRFALSNLRDFGMGKRGSEEKIIEEIHHLKGEFDKFEGKPFDTTQPVNYAVSNIISSIVYGSRFEYIDPRFTEMVARANENVRVGGSFSMMIYNIF-------PWLGPF--LKNRAVVVKNITQNRA-EKKKLITALLETLNPHDPRGFVDSFLIHKLSDEKSGKKDSYFHEENLMLTVANLFAAGTDTTGTTLRWGLMLMAKYPHIQDRVQEEIDRVIG-GRQPVVDDRKKLPYTDAVIHEIQRLANIVPLSLPHRTTSDITFNGYFIKKGTTVVPLLTSVLKDESEWEKPNSFYPEHFLDE----KGQFVKRDAFMPFSAGRRVCLGESLARMELFLFFTSLLQSYR 493          

Query:  259 FYKHAKTYGEIFKFKLGNRELVIINSSKILFKTLKDQGVNFSGRQQNDLIKYITHDCGIVFKEKEWWSTQRSFALKVLRDFGLGKQRSIEIVNNECSILLQELEETSGKNICTKSCFPSVTVNIIAKLLMNMRFEKNSSEFFEFRKIIEQTTHNRSFLVILFQIYTLPHFTIPFIARFSGLRNHIDAVHNFVINIINERKKTFSHENEGQDFIDMFLIEKHKLESENVKNHTFTDWQLIRMVVELFGAGFESTSTTLSWAMVLLARHTEIQDKVHQEIINLIGVDKIPDLNNKKFLHYTQAVMDEILRISTVAPLAVPHRVFNDAEVEGFYIPKDSTIFTNLYACHRDEKVWEKPFDFYPEHFLTKLDNGEMKYTPREELVPFSTGKRQCPGESLARLEYFVFLTSILQKF 1491
             +K +K YG ++   +G R +V+++  K + + L +    F  R  + + +      GIVF   E W   R FAL  LRDFG+GK+RS E++  E   L +E+E   GK   TK        N+IA ++ ++RFE NS +F   R I+    + +       Q+Y +  +   F+A    + +++      +  I+N  KKT + ++  +   D FLI++ K +     +  +     +  +  LFGAG ++T TTL W ++L+A++ EIQ KVH EI ++IG ++ P  +++K L YT AV+ EI R + + P+ +  +   D  + G+ I K +++F  + +  RDE  WE P  F P+HFL K    + ++  ++  +PF  G+R C GESLAR+E F+F TS+LQ F
Sbjct:   65 LWKLSKQYGPVYTVHMGPRTVVVLSGYKAVKEALVNLSEEFGERDISPIFQDFNEGYGIVFSNGENWKEMRRFALSNLRDFGMGKKRSEELITEEIKYLKEEIERFGGKPFETKLPLAMAISNVIALIVYSIRFEYNSPKF--HRAIVRANENAKLVGSPSVQLYNMFPWLRLFVANQKRVVDNVQESFKQIGEIVNGLKKTLNPQSP-RGIADKFLIQQQKDKESGKTDSLYNSNNFLTTINNLFGAGIDTTVTTLRWGLLLIAKYPEIQAKVHDEIDSVIG-ERQPVPDDRKNLPYTDAVIHEIQRFADILPIGLLRQTSCDVYLNGYLIKKGTSVFPLIASVLRDENEWETPDSFNPKHFLNK----QGQFVKKDAFMPFGAGRRLCIGESLARMELFLFFTSLLQHF 467          

Query:   94 LLNVLISIFLVIILYFLSRKFSTNPIPIGLRPLQGPSGWPLVGNL--FSIKEPLWSIFYKHAKTYGEIFKFKLGNRELVIINSSKILFKTLKDQGVNFSGRQQNDLIKYITHDCGIVFKEKEWWSTQRSFALKVLRDFGLGKQRSIEIVNNECSILLQELEETSGKNICTKSCFPSVTVNIIAKLLMNMRFEKNSSEFFEFRKIIEQTTH-NRSFLVILFQIYTLPHFTIPFIARFSGLRNHIDAVHNFVINIINERKKTFSHENEGQDFIDMFLIEKHKLESENVKNHTFTDWQLIRMVVELFGAGFESTSTTLSWAMVLLARHTEIQDKVHQEIINLIGVDKIPDLNNKKFLHYTQAVMDEILRISTVAPLAVPHRVFNDAEVEGFYIPKDSTIFTNLYACHRDEKVWEKPFDFYPEHFLTKLDNGEMKYTPREELVPFSTGKRQCPGESLARLEYFVFLTSILQKF 1491
            LL+V+I IFL  I Y        +P         GP   PL+GNL   ++K+P  + F + A+ YG ++  KLG R++V++  +  +   L +    FSGR +  +   +++  GIVF   E W   R F L  LRDFG+GK+   + ++ E   L+   +   GK         +   NII  +L+N RFE       +  KI+ +      S +V+L+  Y      IP   R   +  +   +++F+      R +     N+ +D ID+FL+++ + +  + K   F D  L  ++  LFGAG E+TSTTL W ++L+ ++ E+Q KV  +I  +IG  + P L ++K + YT AV+ EI R + +AP  VPH    D    GF+IPK + I   L +  RD+  ++KP +FYPEHFL    + +  +   E  +PFS GKR C GE+LA++E F+F T +LQ F
Sbjct:    7 LLSVVICIFLYKIFYGGKETPENSP--------PGPKPLPLIGNLHMINMKKPHLT-FMELAEKYGSVYSVKLGTRDVVVLCGTDTVRDALINHAEEFSGRAKIPVFDEVSNGHGIVFAHGENWKVMRRFTLSTLRDFGMGKKTIEDRISEESDCLVGVFKSYEGKPFDNTMIMNAAVANIIVHILLNHRFEYQDPTLLKLIKIVSENIRIGGSPIVMLYNTYPSIMRWIP--GRHKTVGANTAKLYDFLKETFT-RHREHLDVNDQRDLIDVFLVKQQEEKLSSTK--FFHDENLTVLLGNLFGAGMETTSTTLRWGLLLMMKYPEVQKKVQDDIDRVIGSAE-PRLEHRKLMPYTDAVIHEIQRFANIAPTNVPHATTKDVTFRGFFIPKGTQIMPLLTSVLRDKAYFKKPEEFYPEHFL----DSDGNFVKNEACLPFSAGKRSCAGETLAKMELFLFFTKLLQNF 456          

Query:   94 LLNVLISIFLVIILYFLSRKFSTNPIPIGLRPLQGPSGWPLVGNL--FSIKEPLWSIFYKHAKTYGEIFKFKLGNRELVIINSSKILFKTLKDQGVNFSGRQQNDLIKYITHDCGIVFKEKEWWSTQRSFALKVLRDFGLGKQRSIEIVNNECSILLQELEETSGKNICTKSCFPSVTVNIIAKLLMNMRFEKNSSEFFEFRKIIEQTTH-NRSFLVILFQIYTLPHFTIPFIARFSGLRNHIDAVHNFVINIINERKKTFSHENEGQDFIDMFLIEKH--KLESENVKNHTFTDWQLIRMVVELFGAGFESTSTTLSWAMVLLARHTEIQDKVHQEIINLIGVDKIPDLNNKKFLHYTQAVMDEILRISTVAPLAVPHRVFNDAEVEGFYIPKDSTIFTNLYACHRDEKVWEKPFDFYPEHFLTKLDNGEMKYTPREELVPFSTGKRQCPGESLARLEYFVFLTSILQKF 1491
            LL+V+I IFL  I Y        +P         GP   PL+GNL   ++K+P  + F + A+ YG +F F+ G R+ V++  +  +   L +    FS R +  + + IT   GIVF   E W   R F L  LRDFG+GK+   + +  E   L++  +  +GK         S   NII  +L+  RF+       +  K++ Q       F+  L+ IY      IP       +  +I  V+ F+     E +K     N+ +D ID FL+++   KL S+      F +  L  +V  LF AG E+TSTTL W ++L+ ++ EIQ K+ +EI  +IG  + P L ++K + YT AV+ EI R + +AP  VPH    D    G++IPK + +   L +  RD+  ++KP +FYPEHFL    + E K+   E  +PFS G+R C GE+LA++E F+F T +LQ F
Sbjct:    7 LLSVVICIFLYKIFYGGKETPENSP--------PGPKPLPLIGNLHMINMKKPHLT-FMELAEKYGSVFSFEFGLRKTVVLCGTDTVRDALINHAEEFSERARIPVFEDITKGHGIVFAHGENWKVMRRFTLSTLRDFGMGKKTIEDKICEESDCLVEIFKSYNGKPFDNTLILNSAVANIIVTILLGDRFDYKDPTLLKLVKVVNQNIRIGGGFMARLYNIYPSVMRWIP--GDHKTVFKNIAKVYKFLNKTFTEHRKVLD-VNDQRDLIDAFLVKQQEEKLSSKKF----FHNQNLTVLVANLFAAGMETTSTTLRWGLLLMMKYPEIQKKIQEEIDRVIGSAE-PRLEHRKLMPYTDAVIHEIQRFANIAPNNVPHETTQDVTFRGYFIPKGTQVIPMLTSVLRDKAYFKKPEEFYPEHFL----DSEGKFVKNEAFLPFSAGRRSCAGETLAKMELFLFFTKLLQNF 456          

Query:  115 IFLVIILYFLS--RKFSTNPIPIGLRPLQGPSGWPLVGNLFSI--KEPLWSIFYKHAKTYGEIFKFKLGNRELVIINSSKILFKTLKDQGVNFSGRQQNDLIKYITHDCGIVFKEKEWWSTQRSFALKVLRDFGLGKQRSIEIVNNECSILLQELEETSGKNICTKSCFPSVTVNIIAKLLMNMRFEKNSSEFFEFRKIIEQTTHNRSFLVILFQIYTLPHFTIPFIARFSG----LRNHIDAVHNFVINIINERKKTFSHENEGQDFIDMFLIEKHKLESENVKNHT-FTDWQLIRMVVELFGAGFESTSTTLSWAMVLLARHTEIQDKVHQEIINLIGVDKIPDLNNKKFLHYTQAVMDEILRISTVAPLAVPHRVFNDAEVEGFYIPKDSTIFTNLYACHRDEKVWEKPFDFYPEHFLTKLDNGEMKYTPREELVPFSTGKRQCPGESLARLEYFVFLTSILQKFKIKFNKAIDDI 1524
            + +V +LY LS  ++ + N  P       GP GWPLVGN+FSI  K+P    + + +K YG +F  ++G +++VI+   + +   L      F GR    + K +    G++F   E W   R F +  L+DFG+GK    E + +ECS L+Q      GK     +   +   NII  +L+  R E     F     +      N  ++ +L       +   P +    G    ++ ++  ++ F+     E +K F   ++ + FID+FL  + K E+++ + ++ F +  L+R+V  LF AG E+TST L WA++L+ ++ +IQ+KVH EI  +IG    P  +++  + +T AV+ EILR + + PL+VPH    D   +G++IPK + I   L +  +D+  ++ P  F P HFL    + E  +  +E  +PFS G+R CPGE LAR+E F+F TS+LQKF  +    + +I
Sbjct:   12 VLVVTVLYILSNWKRKALNNFP------PGPKGWPLVGNVFSIDLKKP-QRTYIELSKKYGPVFSVQMGRKKMVILVGYETVKDALVTHAEEFGGRAYIPVTKDLEKGLGMIFSNGENWKAMRRFTITTLKDFGMGKSTIEETIAHECSYLVQYFASFKGKPFDNSTILITSVANIIVAILLGHRMEYEDPVFLRLVNL------NSEYVKLLGSPMVTIYNMFPALGFLPGCHKTVKKNLKELYAFLKRTFVEYQKKFDIHDQ-RSFIDVFL-ARQKEEAKHPETYSYFHNENLVRLVRNLFSAGMETTSTALRWALLLMIKYPDIQEKVHDEISRVIGSVH-PTYSHRTQMPFTNAVIHEILRFADIVPLSVPHETTRDVHFKGYFIPKGTYIIPLLTSVLKDKTQFDAPEQFNPNHFL----DSEGNFLKKEAFMPFSAGRRACPGEILARMELFIFFTSLLQKFSFRPPPGVTNI 470          

Query:  115 IFLVIILYFLS--RKFSTNPIPIGLRPLQGPSGWPLVGNLFSI--KEPLWSIFYKHAKTYGEIFKFKLGNRELVIINSSKILFKTLKDQGVNFSGRQQNDLIKYITHDCGIVFKEKEWWSTQRSFALKVLRDFGLGKQRSIEIVNNECSILLQELEETSGKNICTKSCFPSVTVNIIAKLLMNMRFEKNSSEFFEFRKIIEQTTHNRSFLVILFQIYTLPHFTIPFIARFSGLRNHIDA----VHNFVINIINERKKTFSHENEGQDFIDMFLIEKHKLESENVKNHTFTDWQLIRMVVELFGAGFESTSTTLSWAMVLLARHTEIQDKVHQEIINLIGVDKIPDLNNKKFLHYTQAVMDEILRISTVAPLAVPHRVFNDAEVEGFYIPKDSTIFTNLYACHRDEKVWEKPFDFYPEHFLTKLDNGEMKYTPREELVPFSTGKRQCPGESLARLEYFVFLTSILQKFKIKFNKAIDDI 1524
            + +V +LY LS  ++ + N  P       GP GWPLVGN+FSI  K+P    + + +K YG +F  ++G +++VI+   + +   L      F GR    + K +    GI F   E W   R F +  L+DFG+GK    E + +ECS L+Q      GK     +   +   NIIA +L   R E     F     +      N  ++ +L       +   P +    G    I+     ++ FV     E +K     ++ + FID+FL  + +          F +  L+R+V  +F AG E+TST+L WA++L+ ++ +IQ+KVH EI  +IG    P  +++  + +T AV+ EILR + + PL+VPH    D   +G++IPK + I   L +  +D+  ++ P +F P HFL    + E  +  +E  +PFS G+R CPGE LAR+E F+F TS+LQKF       + +I
Sbjct:   12 VLVVTVLYILSNWKRKALNNFP------PGPKGWPLVGNVFSIDLKKP-QRTYIELSKKYGPVFSVQMGRKKMVILVGYETVKDALVTHAEEFGGRASIPVNKNLEKGLGITFSNGENWKAMRRFTITTLKDFGMGKSTIEETIAHECSYLVQYFASFKGKPFDNSTILSTSVANIIAPILFGHRMEYEDPVFLRLVNL------NSEYVKLLGSPMVTIYNMFPALGFLPGCHKTIEKNLKELYAFVRRTFVEHQKHLDIHDQ-RSFIDVFLARQKEEAKHPETKSYFHNENLVRLVRNVFSAGMETTSTSLRWALLLMIKYPDIQEKVHDEISRVIGSAH-PTYSHRTQMPFTNAVIHEILRFADIVPLSVPHETTRDVHFKGYFIPKGTYIIPLLSSVLKDKTQFDAPEEFNPNHFL----DSEGNFLKKEAFMPFSAGRRACPGEILARMELFIFFTSLLQKFSFHSPPGVTNI 470          

Query:  196 GPSGWPLVGNL--FSIKEPLWSIFYKHAKTYGEIFKFKLGNRELVIINSSKILFKTLKDQGVNFSGRQQNDLIKYITHDCGIVFKEKEWWSTQRSFALKVLRDFGLGKQRSIEIVNNECSILLQELEETSGKNICTKSCFPSVTVNIIAKLLMNMRFEKNSSEFFEFRKIIEQTTH-NRSFLVILFQIYTLPHFTIPFIARFSGLRNHIDAVHNFVINIINERKKTFSHENEGQDFIDMFLIEKH--KLESENVKNHTFTDWQLIRMVVELFGAGFESTSTTLSWAMVLLARHTEIQDKVHQEIINLIGVDKIPDLNNKKFLHYTQAVMDEILRISTVAPLAVPHRVFNDAEVEGFYIPKDSTIFTNLYACHRDEKVWEKPFDFYPEHFLTKLDNGEMKYTPREELVPFSTGKRQCPGESLARLEYFVFLTSILQKF 1491
            GP   PL+GNL   ++++P  + F + AKTYG +F  +LG R+ V++  +  +   L +    FS R +  + + IT   GIVF   E W   R F L  LRDFG+GK+   + +  E   L++  +  +GK         S   NII  +L+  RF+       +  K++ Q       F+  L+ IY      IP       +  +I  V+ F+     E +K     N+ +D ID FL+++   KL S+      F +  L  +V  LF AG E+TSTTL W ++L+ ++ EIQ K+ +EI  +IG  + P L ++K + YT AV+ EI R + +AP  VPH    D    G++IPK + +   L +  RD+  ++KP +FYPEHFL    + E K+   E  +PFS G+R C GE+LA++E F+F T +LQ F
Sbjct:   37 GPKPLPLIGNLHIMNMRKPHLT-FMELAKTYGSVFSVQLGLRKTVVLCGADTVRDALINHAEEFSERARIPVFEDITKGHGIVFAHGENWKVMRRFTLSTLRDFGMGKKTIEDKICEESDSLVEIFKSYNGKPFDNTLILNSAVANIIVTILLGDRFDYKDPTLLKLVKVVNQNIRIGGGFMARLYNIYPSVMRWIP--GDHKTVFKNIAKVYKFLNKTFTEHRKVLD-VNDQRDLIDAFLVKQQEEKLSSKKF----FHNQNLTVLVANLFAAGMETTSTTLRWGLLLMMKYPEIQKKIQEEIDRVIGSAE-PRLEHRKLMPYTDAVIHEIQRFANIAPNNVPHETTQDVTFRGYFIPKGTQVIPMLTSVLRDKAYFKKPEEFYPEHFL----DSEGKFVKNEAFLPFSAGRRSCAGETLAKMELFLFFTKLLQNF 460          

Query:   91 TLLNVLISIFLVIILYFLSRKFSTNPIPIGLRPLQGPSGWPLVGNLFSIK--EPLWSIFYKHAKTYGEIFKFKLGNRELVIINSSKILFKTLKDQGVNFSGRQQNDLIKYITHDCGIVFKEKEWWSTQRSFALKVLRDFGLGKQRSIEIVNNECSILLQELEETSGKNICTKSCFPSVTVNIIAKLLMNMRFEKNSSEFFEFRKIIEQTTHNRSFLVILFQIYTLPHFTIPFIARF-SGLRNHI----DAVHNFVINIINERKKTFSHENEGQDFIDMFLIEKHKLESENVKNHTFTDWQLIRMVVELFGAGFESTSTTLSWAMVLLARHTEIQDKVHQEIINLIGVDKIPDLNNKKFLHYTQAVMDEILRISTVAPLAVPHRVFNDAEVEGFYIPKDSTIFTNLYACHRDEKVWEKPFDFYPEHFLTKLDNGEMKYTPREELVPFSTGKRQCPGESLARLEYFVFLTSILQKFKIKFNKAIDDITYEKITRG 1548
            TLL   ++ FL++  YF +R+    P         GP G P VGN+F +   +P  SI     K YG IF   LG+   V+I    ++ + L     N   R  + + + I++  G++F   + W  QR FAL  LR+FGLGK+   E +  E S L++ + E  GK         +   NII  +    RF+ + S F E  +++++  +  +   ++ Q+Y +     P+I ++  G    +    + +  FV  +I++ +K + + +E +DFID FL E  K      K  +F +  LI   ++LF AG E+TSTTL WA++ +A + E+Q+KV  EI  +IG  +   L +++ + YT AV+ E+ R+  + PL VP  V  D  + GF++PK + + TNL A HRD K W  P  F PEHF   L+NG+ K   RE  +PFS GKR C GE LAR E F+F TS++QKF   FN  I++    K   G
Sbjct:   20 TLLVAAVT-FLLLADYFKNRRPKNYP--------PGPWGLPFVGNIFQLDFGQPHLSI-QPLVKKYGNIFSLNLGDITSVVITGLPLIKEALTQMEQNIMNRPLSVMQERISNKNGLIFSSGQIWKEQRRFALMTLRNFGLGKKSLEERMQEEASHLVEAIREEEGKPFNPHFSINNAVSNIICSVTFGERFDYHDSRFQEMLRLLDEVMYLET--TMISQLYNI----FPWIMKYIPGSHQKVFRNWEKLKLFVSCMIDDHRKDW-NPDEPRDFIDAFLKEMTKYPE---KTTSFNEENLICSTLDLFFAGTETTSTTLRWALLYMALYPEVQEKVQAEIDRVIGQKRAARLADRESMPYTNAVIHEVQRMGNIIPLNVPREVAMDTNLNGFHLPKGTMVLTNLTALHRDPKEWATPDVFNPEHF---LENGQFKK--RESFLPFSMGKRACLGEQLARSELFIFFTSLMQKF--TFNPPINEKLSPKFRNG 485          

Query:  109 ISIFLVIILYFLS----RKFSTNPIPIGLRPLQGPSGWPLVGNLFSIK-EPLWSIFYKHAKTYGEIFKFKLGNRELVIINSSKILFKTLKDQGVNFSGRQQ---NDLIKYITHDCGIVF-KEKEWWSTQRSFALKVLRDFGLGKQRSIEIVNNECSILLQELEETSGKNICTKSCFPSVTVNIIAKLLMNMRFEKNSSEFFEFRKIIEQTTHNRS-FLVILFQIYTLPHFTIPFIARFSGLRNHI----DAVHNFVINIINERKKTFSHENEGQDFIDMFLIEKHKLESENVKNHTFTDWQLIRMVVELFGAGFESTSTTLSWAMVLLARHTEIQDKVHQEIINLIGVDKIPDLNNKKFLHYTQAVMDEILRISTVAPLAVPHRVFNDAEVEGFYIPKDSTIFTNLYACHRDEKVWEKPFDFYPEHFLTKLDNGEMKYTPREELVPFSTGKRQCPGESLARLEYFVFLTSILQKFKIK 1500
            I+IF VI L  ++    R+  T   P       GP  WP++GNL  +  + + + F K    YG++F  +L +  +V++N    L + L     + + R     NDL+ +     GIV  +    W  QR F++  +  FGLGK+   + V  E   L     + +G      +       N+IA LL   RFE +   F     ++++T    + FL +   ++       P + R  GL   +     A    +  ++ E K T+      +D  D FL E  K  ++     +F D  L  +V +LF AG  +TSTTLSWA++L+  H ++Q +V QEI  +IG  + P++ ++  + YT AV+ E+ R + + PL VPH+   D E++GF IPK +T+ TNL +  +DE VWEKP  F+PEHFL    + +  +   E  +PFS G+R C GE LAR+E F+F T +LQ+F I 
Sbjct:   12 IAIFTVIFLILVNLMHWRQRWTAHYP------PGPMPWPVLGNLLHMDFQNMPAGFQKLRGRYGDLFSLQLASESVVVLNGLTALREALVKHSEDTADRPPLHFNDLLGFGPRSQGIVLARYGPAWRQQRRFSVSTMHHFGLGKKSLEQWVTEEARCLCAAFADHTGHPFSPNTLLDKAVCNVIASLLYACRFEYDDPRFIRLLGLLKETLKEEAGFLPMFLNVF-------PMLLRIPGLVGKVFPGKRAFVTMLDELLAEHKTTWDPTQPPRDLTDAFLAEVEK--AKGNPESSFNDENLRTVVGDLFSAGMVTTSTTLSWALMLMILHPDVQRRVQQEIDEVIGQVQCPEMADQARMPYTNAVIHEVQRFADILPLGVPHKTSRDIELQGFLIPKGTTLITNLSSALKDETVWEKPLCFHPEHFL----DAQGHFVKPEAFMPFSAGRRSCLGEPLARMELFLFFTCLLQRFSIS 470          

Query:  103 VLISIFLVIILYFLSRKFSTNPIPIGLRPLQGPSGWPLVGNLFSIK-EPLWSIFYKHAKTYGEIFKFKLGNRELVIINSSKILFKTLKDQGVNFSGRQQNDLIKYITHDCGIVFKEKEWWSTQRSFALKVLRDFGLGKQRSIEIVNNECSILLQELEETSGKNICTKSCFPSVTVNIIAKLLMNMRFEKNSSEFFEFRKIIEQTTHNRSFLVILFQIYTLPHFTIPFI--ARFSGLRNHIDAVHNFVINIINERKKTFSHENEGQDFIDMFLIEKHKLESENVKNHTFTDWQLIRMVVELFGAGFESTSTTLSWAMVLLARHTEIQDKVHQEIINLIGVDKIPDLNNKKFLHYTQAVMDEILRISTVAPLAVPHRVFNDAEVEGFYIPKDSTIFTNLYACHRDEKVWEKPFDFYPEHFLTKLDNGEMKYTPREELVPFSTGKRQCPGESLARLEYFVFLTSILQKFKIK 1500
            VL ++  +++ ++L  +   N  P       GP   P VGNLF +  E    +  +  K YG +     GN   VII    ++ +   +   NF  R    + K + ++ G++    + W  QR FAL  L++FGLGK+   + +  E   L++ + E  G+         S   NII       RFE   S F E  +++++ T   + ++   Q+Y +    I ++  +  + LRN  + +  F+  ++   +K ++  +E +DFID FL E  K   +     +F +  LI   ++LF AG E+T+ TL WA++ +  + E+Q+KVH EI  +IG  + P  +++  + YT AV+ E+LR+  + P+ VP  V  D+ + GF++PK + + TNL A HRD K W  P  F PEHF   L+NG+ K   RE  +PFS GKR CPGE LAR E F+F T+++QKF  K
Sbjct:   22 VLAAVTFMLLAHYLKTQRPKNYPP-------GPWRLPFVGNLFQLDLEQPHVVIQQFVKKYGNLTSLDFGNIPSVIITGLPLIKEVFTNMEQNFLNRPITPIRKRVFNNNGLIISNGQTWKEQRRFALMTLKNFGLGKKSLEQRIQKEADCLVEAIGEEKGQPFDPHFKINSAVSNIICTFAFGERFEYEDSHFHELLRLLDEATCLEASMMC--QLYNVFPSIIQYVPGSHQTVLRN-WEKLKLFIYQMMESHRKDWN-PDEPRDFIDAFLTEMSKYGDKTTT--SFNEENLINSTLDLFFAGSETTTNTLRWALLYITTNPEVQEKVHSEIDRVIGHGRQPSTDDRDSMPYTNAVIHEVLRMGNILPMNVPREVTADSTLAGFHLPKGTMVLTNLTALHRDPKEWATPNTFNPEHF---LENGQFKK--RESFLPFSLGKRACPGEQLARSELFIFFTALMQKFTFK 472          

Query:  196 GPSGWPLVGNLFSIK-EPLWSIFYKHAKTYGEIFKFKLGNRELVIINSSKILFKTLKDQGVNFSGRQQNDLIKYITHDCG----IVFKEKEWWSTQRSFALKVLRDFGLGKQRSIEIVNNECSILLQELEETSGKNICTKSCFPSVTVNIIAKLLMNMRFEKNSSEFFEFRKIIEQTTHNRSFLVILFQIYTLPHFTIPFIARFSGLRNHI----DAVHNFVINIINERKKTFSHENEGQDFIDMFLIEKHKLESENVKNHTFTDWQLIRMVVELFGAGFESTSTTLSWAMVLLARHTEIQDKVHQEIINLIGVDKIPDLNNKKFLHYTQAVMDEILRISTVAPLAVPHRVFNDAEVEGFYIPKDSTIFTNLYACHRDEKVWEKPFDFYPEHFLTKLDNGEMKYTPREELVPFSTGKRQCPGESLARLEYFVFLTSILQKFK 1494
            GP  WP++GNL  +  + +    YK    YG++F  ++G + +V+IN  K + + L   G + + R Q  + +Y+    G    ++      W  QR F++  LR+FGLGK+   + V  E   L       +G+ I   +   +   N+IA L+   RFE         +K++E +    S L+   ++  +     P + R  GL   +     ++   V N++ E + T+  +   ++  D FL E  K++       +F D  L  +V++LF AG  +TSTTLSWA++L+  H ++Q +V QEI  +IG  + P++ ++  + YT AV+ E+ R   +APL +P     D EV+ F IPK S +  N+ +  +DE VWEKP  F+PEHFL    + +  +   E  +PFS G+R C GE LAR+E F+F T +LQ F 
Sbjct:   39 GPVPWPVLGNLLQVDLDNMPYSLYKLQNRYGDVFSLQMGWKPMVVINGLKAMKEVLLTCGEDTADRPQVPIFEYLGVKPGSQGVVLAPYGPEWREQRRFSVSTLRNFGLGKKSLEDWVTKEARHLCDAFTAQAGQPINPNTMLNNAVCNVIASLIFARRFEYEDPYLIRMQKVLEDSLTEISGLIP--EVLNM----FPILLRIPGLPGKVFQGQKSLLAIVENLLTENRNTWDPDQPPRNLTDAFLAEIEKVKGN--AESSFNDENLRMVVLDLFTAGMVTTSTTLSWALLLMILHPDVQRRVQQEIDAVIGQVRHPEMADQARMPYTNAVIHEVQRFGDIAPLNLPRITSRDIEVQDFLIPKGSILIPNMSSVLKDETVWEKPLRFHPEHFL----DAQGHFVKPEAFMPFSAGRRSCLGEPLARMELFLFFTCLLQHFS 468          

Query:   94 LLNVLISIFLVIILYFLSRKFSTNPIPIGLRPLQGPSGWPLVGNLFSI-KEPLWSIFYKHAKTYGEIFKFKLGNRELVIINSSKILFKTLKDQGVNFSGRQQNDLIKYITHDCGIVFKEKEWWSTQRSFALKVLRDFGLGKQRSIEIVNNECSILLQELEETSGKNICTKSCFPSVTVNIIAKLLMNMRFEKNSSEFFEFRKIIEQT-THNRSFLVILFQIYTLPHFTIPFIARFSGLRNHIDAVHNFVINIIN---ERKKTFSHENEGQDFIDMFLIEKHKLESENVKNHT-FTDWQLIRMVVELFGAGFESTSTTLSWAMVLLARHTEIQDKVHQEIINLIGVDKIPDLNNKKFLHYTQAVMDEILRISTVAPLAVPHRVFNDAEVEGFYIPKDSTIFTNLYACHRDEKVWEKPFDFYPEHFLTKLDNGEMKYTPREELVPFSTGKRQCPGESLARLEYFVFLTSILQKFKIKFNKAIDDITYEKITRGTDGTVRAPLDVDLIFEMR 1602
            LL + ++   +I L   S+  +    P G RPL      P +GNL  + +  L S F +  + YG++F   LG R +V++  +  + + L +Q   FSGR    ++  I    G++F   E W T R F+L  +RDFG+GK+   E +  E   L++EL++  G  +     F  +  NII  ++   RF+    +F     +I QT +   S    +F++++        +  F G    I      +++ I    E+ +     +  +DFID +L+   ++E E   +HT F    L+  V+ LF AG E+TSTTL ++ +++ ++  + +KV +EI  +IG  ++P L+++  + YT AV+ EI R + +AP+ +PH+V  D    G+ IPK++ ++  L +   D + +E+P  F PEHFL    NG +K    E  +PFSTGKR C GE +AR E F+F T+ILQ F +    A ++I    +     G  + P    + F  R
Sbjct:    6 LLLLALTTGFLIFLVSQSQPKTHGHFPPGPRPL------PFLGNLLQMDRRGLLSSFIQLQEKYGDVFTVHLGPRPVVMLCGTDTIREALVNQAEAFSGRGTVAVLDPIVQGYGVIFSSGERWKTLRRFSLATMRDFGMGKRSVEERIKEEAQCLVEELKKYKGAPLNPTFYFQCIVANIICSIVFGERFDYKDHQFLHLLNLIYQTFSLMSSLSSQVFELFSA------ILKYFPGAHRQISKNLQEILDYIGHSVEKHRATLDPSAPRDFIDTYLL---RMEKEKSNHHTEFHHQNLVISVLSLFFAGTETTSTTLRYSFLIMLKYPHVAEKVQKEIDQVIGSHRLPTLDDRTKMPYTDAVIHEIQRFTDLAPIGLPHKVTKDTLFRGYLIPKNTEVYPILSSALHDPRYFEQPDSFNPEHFLDA--NGALKTN--EAFMPFSTGKRICLGEGIARNELFLFFTTILQNFSLASPVAPENI---DLIPNNSGATKTPPQYQIHFLSR 492          

Query:   91 TLLNVLISIFLVIILYFLSRKFSTNPIPIGLRPLQGPSGWPLVGNLFSIK--EPLWSIFYKHAKTYGEIFKFKLGNRELVIINSSKILFKTLKDQGVNFSGRQQNDLIKYITHDCGIVFKEKEWWSTQRSFALKVLRDFGLGKQRSIEIVNNECSILLQELEETSGKNICTKSCFPSVTVNIIAKLLMNMRFEKNSSEFFEFRKIIEQTTHNRSFLVILFQIYTLPHFTIPFIARF-SGLRNHI----DAVHNFVINIINERKKTFSHENEGQDFIDMFLIEKHKLESENVKNHTFTDWQLIRMVVELFGAGFESTSTTLSWAMVLLARHTEIQDKVHQEIINLIGVDKIPDLNNKKFLHYTQAVMDEILRISTVAPLAVPHRVFNDAEVEGFYIPKDSTIFTNLYACHRDEKVWEKPFDFYPEHFLTKLDNGEMKYTPREELVPFSTGKRQCPGESLARLEYFVFLTSILQKFKIKFNKAIDDITYEKITRG 1548
            TLL   ++ FL++  YF +R+    P         GP G P VGN+F +   +P  SI     K YG IF   LG+   V+I    ++ + L     N   R  + + + I++  G++F   + W  QR FAL  LR+FGLGK+   E +  E S L++ + E  GK         +   NII  +    RF+ + S F E  +++++  +  +   ++ Q+Y +     P+I ++  G    +    + +  FV  +I++ +K + + +E +DFID FL E  K      K  +F +  LI   ++LF AG E+TSTTL WA++ +A + E+Q+KV  EI  +IG  +   L +++ + YT AV+ E+ R+  + PL VP  V  D  + GF++PK + + TNL A HRD K W  P  F PEHF   L+NG+ K   RE  +PFS GKR C GE LAR E F+F TS++QKF   FN  I++    K   G
Sbjct:   20 TLLVAAVT-FLLLADYFKNRRPKNYP--------PGPWGLPFVGNIFQLDFGQPHLSI-QPLVKKYGNIFSLNLGDITSVVITGLPLIKEALTQMEQNIMNRPLSVMQERISNKNGLIFSSGQIWKEQRRFALMTLRNFGLGKKSLEERMQEEASHLVEAIREEEGKPFNPHFSINNAVSNIICSVTFGERFDYHDSRFQEMLRLLDEVMYLET--TMISQLYNI----FPWIMKYIPGSHQKVFRNWEKLKLFVSCMIDDHRKDW-NPDEPRDFIDAFLKEMTKYPE---KTTSFNEENLICSTLDLFFAGTETTSTTLRWALLYMALYPEVQEKVQAEIDRVIGQKRAARLADRESMPYTNAVIHEVQRMGNIIPLNVPREVAMDTNLNGFHLPKGTMVLTNLTALHRDPKEWATPDVFNPEHF---LENGQFKK--RESFLPFSMGKRACLGEQLARSELFIFFTSLMQKF--TFNPPINEKLSPKFRNG 485          

Query:  106 LISIFLVIILYFLSRKFSTNPIPIGLRPLQGPSGWPLVGNLFSIKEPLWSI---FYKHAKTYGEIFKFKLGNRELVIINSSKILFKTLKDQGVNFSGRQQNDLIKYITHDC---GIVFKE-KEWWSTQRSFALKVLRDFGLGKQRSIEIVNNECSILLQELEETSGKNICTKSCFPSVTVNIIAKLLMNMRFEKNSSEFFEFRKIIEQTTHNRSFLVILFQIYTLPHFTIPFIARFSGLRNHI----DAVHNFVINIINERKKTFSHENEGQDFIDMFL--IEKHKLESENVKNHTFTDWQLIRMVVELFGAGFESTSTTLSWAMVLLARHTEIQDKVHQEIINLIGVDKIPDLNNKKFLHYTQAVMDEILRISTVAPLAVPHRVFNDAEVEGFYIPKDSTIFTNLYACHRDEKVWEKPFDFYPEHFLTKLDNGEMKYTPREELVPFSTGKRQCPGESLARLEYFVFLTSILQKF 1491
            +I I LV +++   R  S  P         GP  WP++GNL  +   L ++    YK    YG++F  ++G + +V+IN  K + + L   G + + R +  + ++I +     G+V       W  QR F++  LR+FG+GK+   + V +E S L   L   +G+ +   +       N+IA L+   RF+    +F +  KI++++   ++ L    ++  +     P + R  GL + +          V N++ E KKT+  +   +D  D FL  IEK K   E+    +F D  L  +V +LFGAG  +TS TL+WA++L+  H ++Q +V QEI  +IG  + P++ ++  + +T AV+ E+ R + + P+ +PH+   D EV+GF IPK +T+  NL +  +DE VWEKP  F+PEHFL    N    +   E  +PFS G+R C GE LAR+E F+F T +LQ+F
Sbjct:   17 VIFILLVDLMHRRQRWTSRYP--------PGPVPWPVLGNLLQVD--LCNMPYSMYKLQNRYGDVFSLQMGWKPVVVINGLKAVQELLVTCGEDTADRPEMPIFQHIGYGHKAKGVVLAPYGPEWREQRRFSVSTLRNFGVGKKSLEQWVTDEASHLCDALTAEAGRPLDPYTLLNKAVCNVIASLIYARRFDYGDPDFIKVLKILKESMGEQTGL--FPEVLNM----FPVLLRIPGLADKVFPGQKTFLTMVDNLVTEHKKTWDPDQPPRDLTDAFLAEIEKAKGNPES----SFNDANLRLVVNDLFGAGMVTTSITLTWALLLMILHPDVQCRVQQEIDEVIGQVRHPEMADQAHMPFTNAVIHEVQRFADIVPMNLPHKTSRDIEVQGFLIPKGTTLIPNLSSVLKDETVWEKPLRFHPEHFLDAQGN----FVKHEAFMPFSAGRRACLGEPLARMELFLFFTCLLQRF 467          

Query:  196 GPSGWPLVGNLFSIK-EPLWSIFYKHAKTYGEIFKFKLGNRELVIINSSKILFKTLKDQGVNFSGRQQNDLIKYITHDCG----IVFKEKEWWSTQRSFALKVLRDFGLGKQRSIEIVNNECSILLQELEETSGKNICTKSCFPSVTVNIIAKLLMNMRFEKNSSEFFEFRKIIEQTTHNRSFLVILFQIYTLPHFTIPFIARFSGLRNHI----DAVHNFVINIINERKKTFSHENEGQDFIDMFLIEKHKLESENVKNHTFTDWQLIRMVVELFGAGFESTSTTLSWAMVLLARHTEIQDKVHQEIINLIGVDKIPDLNNKKFLHYTQAVMDEILRISTVAPLAVPHRVFNDAEVEGFYIPKDSTIFTNLYACHRDEKVWEKPFDFYPEHFLTKLDNGEMKYTPREELVPFSTGKRQCPGESLARLEYFVFLTSILQKFK 1494
            GP  WP++GNL  +  + +    YK    YG++F  ++G + +V+IN  K + + L   G + + R Q  + +Y+    G    ++      W  QR F++  LR+FGLGK+   + V  E   L       +G+ I   +   +   N+IA L+   RFE         +K++E +    S L+   ++  +     P + R  GL   +     ++   V N++ E + T+  +   ++  D FL E  K++       +F D  L  +V++LF AG  +TSTTLSWA++L+  H ++Q +V QEI  +IG  + P++ ++  + YT AV+ E+ R   +APL +P     D EV+ F IPK S +  N+ +  +DE VWEKP  F+PEHFL    + +  +   E  +PFS G+R C GE LAR+E F+F T +LQ F 
Sbjct:   39 GPVPWPVLGNLLQVDLDNMPYSLYKLQNRYGDVFSLQMGWKPMVVINGLKAMKEVLLTCGEDTADRPQVPIFEYLGVKPGSQGVVLAPYGPEWREQRRFSVSTLRNFGLGKKSLEDWVTKEARHLCDAFTAQAGQPINPNTMLNNAVCNVIASLIFARRFEYEDPYLIRMQKVLEDSLTEISGLIP--EVLNM----FPILLRIPGLPGKVFQGQKSLLAIVENLLTENRNTWDPDQPPRNLTDAFLAEIEKVKGN--AESSFNDENLRMVVLDLFTAGMVTTSTTLSWALLLMILHPDVQRRVQQEIDAVIGQVRHPEMADQARMPYTNAVIHEVQRFGDIAPLNLPRITSRDIEVQDFLIPKGSILIPNMSSVLKDETVWEKPLRFHPEHFL----DAQGHFVKPEAFMPFSAGRRSCLGEPLARMELFLFFTCLLQHFS 468          

Query:  172 PIGLRPLQGPSGWPLVGNLFSIKEPLWSIFYKHAKTYGEIFKFKLGNRELVIINSSKILFKTLKDQGVNFSGRQQNDLIKYI----THDCGIVFKEKEWWSTQRSFALKVLRDFGLGKQRSIEIVNNECSILLQELEETSGKNICTKSCFPSVTVNIIAKLLMNMRFEKNSSEFFEFRKIIEQTTHN-RSFLVILFQIYT-LPHFTIPFIARFSG---LRNHIDAVHNFVINIINERKKTFSHENEGQDFIDMFLIEKHKLESENVKNHTFTDWQLIRMVV-ELFGAGFESTSTTLSWAMVLLARHTEIQDKVHQEIINLIGVDKIPDLNNKKFLHYTQAVMDEILRISTVAPLAVPHRVFNDAEVEGFYIPKDSTIFTNLYACHRDEKVWEKPFDFYPEHFLTKLDNGEMKYTPREELVPFSTGKRQCPGESLARLEYFVFLTSILQKFKIKFNKA 1512
            P GL P  G  GWPLVG + S  + L     +  K YG+I  +++G R  V + +    FK +K     F    + D   +      +D G+VF     W T R F L+ LRD G+GK R    + +E + L+QEL++ + + +          +N+I KL+ + R+     E   F +++  TT N + F + LF     L   T  F+  + G   LR+ +  + +++   I E + T    N  +D +D +LI+  + + + +        + +R V+ +LFGAG E+TST + W ++ L ++ E+Q K+ +EI   +    +P L +K  L Y +A + E+ RI ++ PL V H    D E+ G+ +PK + + ++L  CHRD   WEKP +FYPEHFL   D G  K+  RE LV FS G+R C GESLAR+E FVFL++ILQ F     K 
Sbjct:   22 PSGLPP--GIWGWPLVGRMPSRSKHLADQVKQLRKKYGDIITWRIGTRVNVFLCN----FKLVKTALSKFECSDRPDFYTFKLFGEGNDVGVVFSNGVMWQTHRRFILRQLRDLGMGKSRLEAAIQHEAACLVQELKKHTDQPMPLPKSINLAVLNVIWKLVADHRYSLQDQEGQYFTQLLTTTTDNMQGFALNLFNYLPWLLMITPDFVKNWMGVRVLRDGVCELKDYMKTFIKEHQATLDPSNP-KDLLDAYLIDLQERKEDPLSTMNI---ETVRAVIMDLFGAGTETTSTMIRWTILYLMKYPEVQAKIQREIDAAVPRGTLPSLEHKDKLAYFEATIHEVHRIVSLVPLGVSHYTNQDTELAGYRLPKGTVVMSHLECCHRDPSYWEKPNEFYPEHFLD--DQG--KFVKREHLVNFSVGRRVCVGESLARMELFVFLSAILQNFTFSAPKG 464          

Query:   94 LLNVLISIFLVIILYFLSRKFSTNPIPIGLRPLQGPSGWPLVGNLFSI-KEPLWSIFYKHAKTYGEIFKFKLGNRELVIINSSKILFKTLKDQGVNFSGRQQNDLIKYITHDCGIVFKEKEWWSTQRSFALKVLRDFGLGKQRSIEIVNNECSILLQELEETSGKNICTKSCFPSVTVNIIAKLLMNMRFEKNSSEFFEFRKIIEQT-THNRSFLVILFQIYTLPHFTIPFIARFSGLRNHIDAVHNFVINIIN---ERKKTFSHENEGQDFIDMFLIEKHKLESENVKNHT-FTDWQLIRMVVELFGAGFESTSTTLSWAMVLLARHTEIQDKVHQEIINLIGVDKIPDLNNKKFLHYTQAVMDEILRISTVAPLAVPHRVFNDAEVEGFYIPKDSTIFTNLYACHRDEKVWEKPFDFYPEHFLTKLDNGEMKYTPREELVPFSTGKRQCPGESLARLEYFVFLTSILQKFKIKFNKAIDDITYEKITRGTDGTVRAPLDVDLIFEMR 1602
            LL + ++   +I L   S+  +    P G RPL      P +GNL  + +  L S F +  + YG++F   LG R +V++  +  + + L +Q   FSGR    ++  I    G++F   E W T R F+L  +RDFG+GK+   E +  E   L++EL++  G  +     F  +  NII  ++   RF+    +F     +I QT +   S    +F++++        +  F G    I      +++ I    E+ +     +  +DFID +L+   ++E E   +HT F    L+  V+ LF AG E+TSTTL ++ +++ ++  + +KV +EI  +IG  ++P L+++  + YT AV+ EI R + +AP+ +PH+V  D    G+ IPK++ ++  L +   D + +E+P  F PEHFL    NG +K    E  +PFSTGKR C GE +AR E F+F T+ILQ F +    A ++I    +     G  + P    + F  R
Sbjct:    6 LLLLALTTGFLIFLVSQSQPKTHGHFPPGPRPL------PFLGNLLQMDRRGLLSSFIQLQEKYGDVFTVHLGPRPVVMLCGTDTIREALVNQAEAFSGRGTVAVLDPIVQGYGVIFSSGERWKTLRRFSLATMRDFGMGKRSVEERIKEEAQCLVEELKKYKGAPLNPTFYFQCIVANIICSIVFGERFDYKDHQFLHLLNLIYQTFSLMSSLSSQVFELFSA------ILKYFPGAHRQISKNLQEILDYIGHSVEKHRATLDPSAPRDFIDTYLL---RMEKEKSNHHTEFHHQNLVISVLSLFFAGTETTSTTLRYSFLIMLKYPHVAEKVQKEIDQVIGSHRLPTLDDRTKMPYTDAVIHEIQRFTDLAPIGLPHKVTKDTLFRGYLIPKNTEVYPILSSALHDPRYFEQPDSFNPEHFLDA--NGALKTN--EAFMPFSTGKRICLGEGIARNELFLFFTTILQNFSLASPVAPENI---DLIPNNSGATKTPPQYQIHFLSR 492          

Query:  163 NPIPIGLRPLQGPSGWPLVGNLFSIKEPLWSIFYKHAKTYGEIFKFKLGNRELVIINSSKILFKTLKDQGVNFSGRQQNDLIKYITHDCGIVFKEKEWWSTQRSFALKVLRDFGLGKQRSIEIVNNECSILLQELEETSGKNICTKSCFPSVTVNIIAKLLMNMRFEKNSSEFFEFRKIIEQTTHNRS---FLVILFQIYTLPHFTIPFIARFSGLRNHIDAVHNFVINIINERKKTFSHENEGQDFIDMFLIEKHKLESENVKNHTFTDWQLIRMVVELFGAGFESTSTTLSWAMVLLARHTEIQDKVHQEIINLIGVDKIPDLNNKKFLHYTQAVMDEILRISTVAPLAVPHRVFNDAEVEGFYIPKDSTIFTNLYACHRDEKVWEKPFDFYPEHFLTKLDNGEMKYTPREELVPFSTGKRQCPGESLARLEYFVFLTSILQKFKIKFNKAIDDITYEKITRGTDGTVRAPLDVDLIF 1593
            N IP GL+      G P++G +  IKEP+ +   K +K +G IF+ KLG R+++I+++  I+ K L D G NFSGR +  LI  ITHD GI+FK+ + WSTQRSF LKVLRDFGLGK +S+++V NECS LL+ELE   GK I      P  T NII+K +MN RFE+ + +     K++ +    +     L I+F            I  F+        + N+    I+E  KT    +EG+D +D FLI++++L+ +N+   +F DWQLIR  +ELF AG+E+TSTTL W+ + +++H +IQ KVH EII +IG +++P +N+KK ++YTQAVMDEI R+S+VAPLA+ HR  NDA ++G++IPK++ IF NLYACH D  +WEKP  FYPEHFLT+ DNG +KYTPR+EL+ FS GKRQC GESLAR+E+F+F TSILQ+F++K  K +++  YE+   G DG +R  +  D IF
Sbjct:   24 NSIPKGLKETPIEYGLPILGIIHKIKEPMHNYLLKLSKKHGPIFRIKLGMRDVLILSNYDIIKKALVDDGQNFSGRWRMKLISLITHDSGIIFKDGQDWSTQRSFVLKVLRDFGLGKSKSVDLVQNECSFLLEELESLEGKIIDFSKIIPIYTANIISKFIMNKRFERENPKIARIEKMLSEEIKKKDIIQLLHIMFPKCDTSGLFCELIINFTSKWKEFLEIQNYFKEEIDEHLKTIDFNSEGEDLMDRFLIKQNQLKQQNIDVGSFNDWQLIRSSLELFYAGYETTSTTLCWSFLFMSKHQDIQQKVHNEIIEIIGKERLPTMNDKKSMNYTQAVMDEIFRMSSVAPLALIHRTLNDANIDGYFIPKNTLIFPNLYACHFDRDIWEKPMIFYPEHFLTEDDNGNLKYTPRDELILFSIGKRQCLGESLARMEFFIFFTSILQRFRVKLVKELNEKEYEEALLGKDGIIRGSIVNDFIF 503          

Query:  106 LISIF-LVIILYFLSRKFSTNPIPIGLRPLQGPSGWPLVGNLFSIKEPLWSIFYKHAKTYGEIFKFKLGNRELVIINSSKILFKTLKDQGVNFSGRQQNDLIKYITHDCGIVFKEKEWWSTQRSFALKVLRDFGLGKQRSIEIVNNECSILLQELEETSGKNICTKSCFPSVTVNIIAKLLMNMRFEKNSSEFFEFRKIIEQTTHNRSF---LVILFQIYTLPHFTIPFIARFSGLRNHIDAVHNFVINIINERKKTFSHENEGQDFIDMFLIEKHKLESENVKNHTFTDWQLIRMVVELFGAGFESTSTTLSWAMVLLARHTEIQDKVHQEIINLIGVDKIPDLNNKKFLHYTQAVMDEILRISTVAPLAVPHRVFNDAEVEGFYIPKDSTIFTNLYACHRDEKVWEKPFDFYPEHFLTKLDNGEMKYTPREELVPFSTGKRQCPGESLARLEYFVFLTSILQKFKIKFNKAIDDITYEKITRGTDGTVRAPLDVDLIFE 1596
            ++SIF L II Y  SR F    IP GL+      GWP++G +  IK P+ +   + ++ +G IF+ +LG R++VI+ + + + K L D    FSGR +  L+  +THD GIVFK+   WSTQRSF LKVLRDFG+GK  S +IV  EC  LL EL+   G+ I      P  T NII+K +MN RF+++          I QT+        L ++F I+        F    +        V     + I E K    + +EG D ID FL+E+++L        +FTD QLI M  E+FGAG+E+TSTTL W+M+ ++R+ +IQ KV++EI+N+IG +++P +N+KK L+YTQAVMDEILR+S+VAPL + HR FND  V+ ++IPK+S +F N YACH D  +W KP +FYPEHFL K +N E+KY+PREEL+PF  GKRQC GESLAR+EYF+F  SILQ++++ F++ I D  +E+  RG +G +R     + IF+
Sbjct:    4 ILSIFGLFIIWYCFSRVFKRRSIPNGLKETPIEYGWPILGIIPKIKGPMQNYLLELSRKHGPIFRIRLGMRDVVILGNYQTIRKALVDDAQIFSGRWKMKLVSVVTHDSGIVFKDGPVWSTQRSFILKVLRDFGMGKSISQDIVQGECLFLLNELDSLQGEIIDFSKIIPIYTANIISKFIMNKRFDRSDPRIKFIEYAIFQTSKQSDIVQRLHLMFPIFDKSTIISKFNLWITSKLQLFSKVERVFHDEIEEHKTNLDYNSEGDDLIDRFLLEQNRLSQSTGIVESFTDKQLIFMTFEMFGAGYETTSTTLGWSMLFMSRYKDIQKKVYEEILNVIGEERMPTMNDKKSLNYTQAVMDEILRLSSVAPLGIFHRTFNDTSVDNYFIPKNSLVFANYYACHTDPDIWLKPVEFYPEHFLIKCENDELKYSPREELIPFGIGKRQCIGESLARMEYFIFFVSILQRYQVDFSENISDSLFEETLRGNEGIIRYSKIKNFIFK 504          

Query:  136 YFLSRKFSTNPIPIGLRPLQGPSGWPLVGNLFSIKEPLWSI-FYKHAKTYGEIFKFKLGNRELVIINSSKILFKTLKDQGVNFSGRQQNDLIKYITHDCGIVFKEKEWWSTQRSFALKVLRDFGLGKQRSIEIVNNECSILLQELEETS--GKNICTKSCFPSVTVNIIAKLLMNMRFEKNSSEFFEFRKIIEQTTHNRSFLVILFQIYTLPHFTIPFIARFSGLRNHIDAVHNFVINIINERKKTFSHENEGQDFIDMFLIEKHKLESENVKNHTFTDWQLIRMVVELFGAGFESTSTTLSWAMVLLARHTEIQDKVHQEIINLIGVDKIPDLNNKKFLHYTQAVMDEILRISTVAPLAVPHRVFNDAEVEGFYIPKDSTIFTNLYACHRDEKVWEKPFDFYPEHFLTKLDNGEMKYTPREELVPFSTGKRQCPGESLARLEYFVFLTSILQKFKIKFNKAIDDITYE-KITRGTDGTVRAPLDVDLIFEMR 1602
            Y  SR +    +P       GP G P++G L  + +    +   +  K YG++  +++G++ +V +NS  +L + ++D+  N++GR +   +  +T  CGI F E E WS QR  A++ LRDFG  + RS E+V+ +  I+ Q LE  +  G +I T   F   T  +IA+L +  R+E+   EF    + I +   N SFL+ +  ++      +  +   S   N +  + +FV N +N+RK+      E +   D+++ E+ + E       TF + Q++R VVE F AG ++T+ +L W +VL+A    IQDKVH+E+I ++G ++ P  ++K  L+YT AV++E  R  ++  + V HR   DA   G+ IPKDS I    Y  + D ++W KP +FYPEHFL    N +  YT   + VPF  G+R CPGE LAR+E  +  ++I+Q+F++    A + +  E +I +G+ G +R P D  L  + R
Sbjct:   27 YLASRWYRNRSLP------PGPVGLPVIGRLPWMDQKQAHLCVIEMCKQYGDLISYRMGSQLMVAVNSYDLLKEIMEDE--NYTGRPRLPFLDRVTQGCGIFFTEGESWSQQRRLAMRSLRDFGFARTRSAEMVDAQVDIIFQLLEAAADNGDHIRTLEAFTEATNGVIAQLTLGRRYERGEKEFIYLNETI-KAFFNTSFLLSMPLLFPSLDVIVRTLPASSSFNNLVFGLQDFVRNQVNQRKEIVDDSMEPECLCDVYIQERRRCEKRG-DYETFKEHQIVRGVVEFFVAGTDTTARSLEWLVVLMAVFPAIQDKVHEELIRVVGSERRPLTSDKSELNYTLAVIEESFRFVSLVAIGVMHRAKQDAIFHGYRIPKDSIILPCTYGINHDSRIWAKPDEFYPEHFL----NEKGAYTGHGKNVPFMIGRRACPGEGLARMEVLLVFSAIMQRFRVTL--APEYVGKEAEILKGSYGILRQPGDYKLSVQKR 503          

Query:  136 YFLSRKFSTNPIPIGLRPLQGPSGWPLVGNLFSIKEPLWSI-FYKHAKTYGEIFKFKLGNRELVIINSSKILFKTLKDQGVNFSGRQQNDLIKYITHDCGIVFKEKEWWSTQRSFALKVLRDFGLGKQRSIEIVNNECSILLQELEETS--GKNICTKSCFPSVTVNIIAKLLMNMRFEKNSSEFFEFRKIIEQTTHNRSFLVILFQIYTLPHFTIPFIARFSGLRNHIDAVHNFVINIINERKKTFSHENEGQDFIDMFLIEKHKLESENVKNHTFTDWQLIRMVVELFGAGFESTSTTLSWAMVLLARHTEIQDKVHQEIINLIGVDKIPDLNNKKFLHYTQAVMDEILRISTVAPLAVPHRVFNDAEVEGFYIPKDSTIFTNLYACHRDEKVWEKPFDFYPEHFLTKLDNGEMKYTPREELVPFSTGKRQCPGESLARLEYFVFLTSILQKFKIKFNKAIDDITYE-KITRGTDGTVRAPLDVDLIFEMR 1602
            Y  SR F    +P       GP   P++G L  + +    +   +  K YG++  +++G++ +V +NS  +L + ++D+  N++GR +   +  +T  CGI F E E WS QR  A++ LRDFG  + RS E+V+ +  I+ Q LE  +  G +I T   F   T  +IA+L +  R+E+   EF    + I +   N SFL+ +  ++      +  +   S   N +  + +FV N +N+RK+      E +   D+++ E+ + E       TF + Q++R VVE F AG ++T+ +L W +VL+A    IQDK+H+E+I ++G ++ P  ++K  L+YT AV++E  R  ++  + V HR   DA   G+ IPKDS I    Y  + D ++W KP +FYPEHFL    N +  YT   + VPF  G+R CPGE LAR+E  +  ++I+Q+F++    A + +  E +I +G+ G +R P D  L  + R
Sbjct:   27 YLASRWFRNRSLP------PGPVALPVIGRLPWMDQKQAHLCVIEMCKQYGDLISYRMGSQLMVAVNSYDLLKEIMEDE--NYTGRPRLPFLDRVTQGCGIFFTEGESWSQQRRLAMRSLRDFGFARTRSAEMVDAQVDIIFQLLEAAADNGDHIRTLEAFTEATNGVIAQLTLGRRYERGEKEFIYLNETI-KAFFNTSFLLSMPLLFPSLDVIVRTLPASSSFNNLVFGLQDFVRNQVNQRKEIVDDSMEPECLCDVYIQERRRCEKRG-DYETFKEHQIVRGVVEFFVAGTDTTARSLEWLVVLMAVFPAIQDKLHEELIRVVGSERRPLTSDKSELNYTLAVIEESFRFVSLVAIGVMHRAKQDAIFHGYRIPKDSIILPCTYGINHDSRIWAKPDEFYPEHFL----NEKGAYTGHGKNVPFMIGRRACPGEGLARMEVLLVFSAIMQRFRVTL--APEYVGKEAEILKGSYGILRQPGDYKLSVQKR 503          

Query:  148 RKFSTNPIPIGLRPLQGPSGWPLVGNLFSIKEPLWSIFYKHAKTYGEIFKFKLGNRELVIINSSKILFKTLKDQGVNFSGRQQNDLIKYITHDCGIVFKEKEWWSTQRSFALKVLRDFGLGKQRSIEIVNNECSILLQELEETSGKNICTKSCFPSVTVNIIAKLLMNMRFEKNSSEFFEFRKIIEQTTHNRSFLVILFQIYTLPHFTIPFIARFSGLR-------NHIDAVHNFVINIINERKKTFSHEN--EGQDFIDMFLIEKHKLESENVKNHTFTDWQLIRMVVELFGAGFESTSTTLSWAMVLLARHTEIQDKVHQEIINLIGVDKIPDLNNKKFLHYTQAVMDEILRISTVAPLAVPHRVFNDAEVEGFYIPKDSTIFTNLYACHRDEKVWEKPFDFYPEHFLTKLDNGEMKYTPREELVPFSTGKRQCPGESLARLEYFVFLTSILQKFKIKFNKAIDDITYEKITRGTDGTVR 1566
            R +   P P+GL P+ G   W  + +L   +E       K    YG I+ +++G+R +++++S ++L + L +    FSGRQ     +    DCGI+F E   WS QR  +L+VLRDFG  +  S+E +N E  IL+++LE+     +     F ++T ++IA L+   R+      +       E+   N  FL  +  +  LP F  P++++   L          +  +  F+   I +R+   S +   EG    D ++IE+   E++     TF  +QL+R+ +ELF AG ++T+ TL W M+ +A   E QD V  EI  + G ++ P L++K  LHYTQAV+DE +R +++AP A+ HR   D    G+ IP D+ I   LY  HR+ K W++P  FYP HFLT+    + +Y P + L PF  GKR CPGESLA+LE F+  T+I+Q+++++F++   +   + I RG  G  R
Sbjct:   51 RVYRLPPGPLGL-PILGRLPWLDLKHLEESQE-------KMRHQYGGIYSYRMGSRLMIVVSSYELLKEMLSED--VFSGRQLPPAAQRTAQDCGILFVEGRVWSEQRRVSLRVLRDFGFARTESVEFINEEICILMEKLEQQP-TEVKVIDHFNALTNSVIAMLVFGRRYANEDKRY-------EKFLENSKFLFDVGLLSELP-FLFPYLSKLLSLLPMTRKIVKTVQDIQTFIEEEITKREALISSDADAEGTCLCDAYIIERRNAEAKG-DFETFKKFQLVRVSMELFVAGTDTTAKTLEWLMIHMAAFPEAQDNVQAEIHQVAGTERQPQLSDKAQLHYTQAVIDESMRFASLAPNAISHRAIKDTYFRGYLIPADAAIVPFLYGLHRNSKYWKRPHTFYPGHFLTE----DGRYAPSKMLEPFCVGKRACPGESLAKLEIFLTFTAIMQRYRVRFSRDY-ETKVDDILRGVCGLAR 507          

Query:  196 GPSGWPLVGNLFS-IKEPLWSIFYKHAKTYGEIFKFKLGNRELVIINSSKILFKTLKDQGVNFSGRQQNDLIKYITHDCGIVFKE-KEWWSTQRSFALKVLRDFGLGKQRSIEIVNNECSILLQELEETSGKNICTKSCFPSVTVNIIAKLLMNMRFEKNSSEFFEFRKIIEQTTHNRSFLVILFQIYTLPHFTIPFIARFSG----LRNHIDAVHNFVINIINERKKTFSHENEGQDFIDMFLIEKHKLESENVKNHTFTDWQLIRMVVELFGAGFESTSTTLSWAMVLLARHTEIQDKVHQEIINLIGVDKIPDLNNKKFLHYTQAVMDEILRISTVAPLAVPHRVFNDAEVEGFYIPKDSTIFTNLYACHRDEKVWEKPFDFYPEHFLTKLDNGEMKYTPREELVPFSTGKRQCPGESLARLEYFVFLTSILQKFKIKFNKAIDDITYEKITRGTDGTVRAPLDVDLIFEMR 1602
            GP     VGNL   +K+ +  I  +    YGE+    LG +  +++NS +I  +     G  FSGR    LI++I    GIV       W  QR FAL  LRDFGLGK+   E V  E   L++E+ +  GK         +   NII  ++   RFE +   F E  +II +        V   QI+ L    +PFI    G    +R ++D+++ F+ + I E +KT   EN  +DFID +L+E  K +  N ++ TF +  ++R  ++LFGAG E+T+ TL W ++ +  H ++Q++ H+EI+ ++G D  P ++++  L YT A + EI R + + PL V H+     ++ G++IP  + I +NL A   D+  W+ P  F PE+FL +    + ++   +  +PFS G R C GE+LAR E F+F TS++Q+ K  +      +  + I     G VRA L  + I   R
Sbjct:   42 GPKPMLFVGNLPQFMKDKMGYI--RSMPKYGEMCSMYLGRKPTIVLNSVQIAKEAFVQNGAVFSGRPSLPLIRWINKGYGIVMATYGNSWRQQRRFALHTLRDFGLGKKSVEERVAEEARYLIKEMLKQEGKPFYPIHPIMNAVSNIICSIVFGDRFEYDDRRFAELLEIINENIRFSGSPVA--QIFNL----VPFIKHLPGPQQKIRQNLDSLNKFIFDEIEEHRKTLDPENP-RDFIDSYLVEMKKQQGSN-EDSTFHENNMVRSTIDLFGAGTETTANTLRWGLIYMMEHPDVQERCHEEIVRVLGFDCFPSMDDRAQLPYTLATVHEIQRYANIVPLGVVHQTTQPTKLRGYHIPAGTNIMSNLTAIMADKDHWKYPNTFNPENFLDE----KGQFCKNDSFLPFSLGPRVCLGETLARTELFIFFTSLIQQLKFSWPPGAPPLNMDGIV----GVVRANLPFNTICRSR 498          

Query:   97 LNVLISIFLVIILYFLSRKFSTNPIPIGLRPLQGPSGWPLVGNLFS-IKEPLWSIFYKHAKTYGEIFKFKLGNRELVIINSSKILFKTLKDQGVNFSGRQQNDLIKYITHDCGIVFKE-KEWWSTQRSFALKVLRDFGLGKQRSIEIVNNECSILLQELEETSGKNICTKSCFPSVTVNIIAKLLMNMRFEKNSSEFFEFRKIIEQTTHNRSFLVILFQIYTLPHFTIPFIARFSGLRNHI----DAVHNFVINIINERKKTFSHENEGQDFIDMFLIEKHKLESENVKNHTFTDWQLIRMVVELFGAGFESTSTTLSWAMVLLARHTEIQDKVHQEIINLIGVDKIPDLNNKKFLHYTQAVMDEILRISTVAPLAVPHRVFNDAEVEGFYIPKDSTIFTNLYACHRDEKVWEKPFDFYPEHFLTKLDNGEMKYTPREELVPFSTGKRQCPGESLARLEYFVFLTSILQKFKIKFNKAIDDITYEKITRGTDGTVRAPLDVDLIFEMR 1602
            L +++ +  + +L       S N  P G +PL      P +GNL   IK+P+   + +    YGE+    LG    +++N+ +I  +     G  FSGR    L +++    GIV       W  QR FAL  LRDFGLGK+   E V  E   L++E+ +  GK         +   NII  ++   RF+ +   F +   I+      R     L QI+ L    +PF+  F G    +     A+  F+  ++ E +KT   EN  +DFID +L+E  K ES   ++ TF    ++R + +LFGAG E+T+ TL W ++ +  + ++Q++ H+EI+ ++G D+ P  N++  L YT A + EI R + +APL V H      +++GF+IP  + I  NL A   D++ W+ P  F PE+FL +    + ++   +  + FS G R C GE+LAR E F+F TS+LQ+ +  +             RGT G VR  L  + I   R
Sbjct:   15 LALVVGLLSLFVLEIFRMNSSRNQSPPGPKPL------PFLGNLPQFIKDPM--TYIRSMPKYGELCSMYLGRNPTIVLNTMQIAKEAFVQNGAVFSGRPSMPLTRWLNKGYGIVMAPYSNSWRQQRRFALHTLRDFGLGKKTVEERVAEEARYLIKEMLKEEGKPFYPSHPIMNAVSNIICSIIFGDRFDYDDKRFAKLLDILNDNV--RLVGSPLAQIFNL----LPFMKHFPGPHQKVWENDVALKEFIFEVVEEHRKTLDQENL-RDFIDAYLVEMMKQESN--EDSTFHKENMLRSITDLFGAGTETTANTLRWGLIYMMDNPDVQERCHEEIVRVLGFDRFPSTNDRSHLPYTYATVHEIQRNANIAPLGVMHTTTQPTQLQGFHIPAGTDIVPNLTAILNDQEHWKYPDMFNPENFLDE----KGQFCKNDSFLAFSLGPRVCLGETLARTELFIFFTSLLQQLRFSWPPGASSPN----KRGTAGIVRTTLPFNTICRSR 497          

Query:  184 RPLQGPSGWPLVGNLFSIKEPLWSIFYKHAKTYGEIFKFKLGNRELVIINSSKILFKTLKDQGVNFSGRQQNDLIKYITHDCGIVFKE-KEWWSTQRSFALKVLRDFGLGKQRSIEIVNNECSILLQELEETSGKNICTKSCFPSVTVNIIAKLLMNMRFEKNSSEFFEFRKII-EQTTHNRSFLVILFQIYTLPHFTIPFIARFSG----LRNHIDAVHNFVINIINERKKTFSHENEGQDFIDMFLIEKHKLESENVKNHTFTDWQLIRMVVELFGAGFESTSTTLSWAMVLLARHTEIQDKVHQEIINLIGVDKIPDLNNKKFLHYTQAVMDEILRISTVAPLAVPHRVFNDAEVEGFYIPKDSTIFTNLYACHRDEKVWEKPFDFYPEHFLTKLDNGEMKYTPREELVPFSTGKRQCPGESLARLEYFVFLTSILQKFKIKFNKAIDDITYEKITRGTDGTVRAPLDVDLIFEMR 1602
            R   GP     VGNL  I +   + F K    YGE+    LG +  +++N+ +I  +     G  FS R  N LI+  T  CGI+       W  QR FAL  LRDFGLGK+   E V  E   L++E+ +  GK         +   NII  ++   RFE +  +F +  +I+ E      SF+    Q Y      IPF+    G    +  +++++  F++ +  E +KT   EN  +DFID +L+E  K ES   ++ TF +  + +   +LF AG E+T+ TL W ++ +  H ++Q++ H+EI+ ++G D+ P ++++  L YT A + EI R + + PL V H       + G++IP+ + I +NL A   D+  W+ P  F PE+FL +    + ++   +  +PFS G R C GE+LAR E F+F TS++Q+ K  +           I     GTVR+ L  + I   R
Sbjct:   38 RSPPGPKPMLFVGNLPQIMKDRMA-FIKMMPKYGEMCSMYLGKKPTIVLNTVQIAKEAFVQNGTVFSSRPDNRLIRKFTQGCGIIMAPYGNSWKQQRRFALHTLRDFGLGKKTVEERVAEEARYLIKEMLKQEGKAFYPIHPIMNAVSNIICSIVFGDRFEYDDKQFAKLLEILNENVRFTGSFIS---QTY----LVIPFVEHLPGPHQKVWKNLNSLREFILGVAEEHRKTLDPENL-RDFIDAYLVEMIKQESN--EDSTFHEENMAKSTADLFSAGTETTANTLRWGLIYMMEHPDVQERCHEEIVRVLGFDRFPSMDDRAQLPYTHATVHEIQRNANIIPLGVMHHTTQPTTLRGYHIPQGTDIMSNLTAILTDKDHWKYPDTFNPENFLDE----KGQFCKNDSFLPFSLGPRVCLGETLARTELFIFFTSLIQRLKFSWPPGAPPPNMNGIV----GTVRSNLPFNTICRSR 497          

Query:  196 GPSGWPLVGNLFSIKEPLWSIFYKH---AKTYGEIFKFKLGNRELVIINSSKILFKTLKDQGVNFSGRQQNDLIKYITHDCGIVFKEKEWWSTQRSFALKVLRDFGLGKQRSIEIVNNECSILLQELEETSGKNICTKSCFPSVTVNIIAKLLMNMRFEKNSSEFFEFRKIIEQTTHN-RSFLVILFQIYTLPHFTIPFIARFSGLRNHIDAVHNFVINIINERKKTFSHENEGQDFIDMFLIEKHKLESENVKNHTFTDWQLIRMVVELFGAGFESTSTTLSWAMVLLARHTEIQDKVHQEIINLIGVDKIPDLNNKKFLHYTQAVMDEILRISTVAPLAVPHRVFNDAEVEGFYIPKDSTIFTNLYACHRDEKVWEKPFDFYPEHFLTKLDNGEMKYTPREELVPFSTGKRQCPGESLARLEYFVFLTSILQKFK 1494
            GP  +P+       K      FY+    AKTYG +FK   G +++V++   K + + L +    F  R+   L K ++ + GI+F   E W   R FAL  LRDFG+GK+ S E +  E   +++E  +  GK   T     +   NII+ ++   RFE +     +F++++ +   N R       ++Y +  +  PF+     L  + +     +  II+  ++T  H ++ + FID FL+ K   E    KN  F D  L+  V+ LF AG ++T TTL W ++L+A++  IQD+VH+EI  +IG  ++  + ++K L YT AV+ EI R + + P+++PH    D    GF+I K +T++  L +  RDE  WE P  F P+HFL K    + ++  ++  +PFS G+R C GESLAR+E F+F TS+LQ F+
Sbjct:   18 GPHSFPM-----EKKRSRLRSFYEKPYLAKTYGSVFKVYFGPKKVVVLAGYKTVKQALVNHAEEFGEREIGKLFKNLSEEHGILFSNGENWREMRRFALTNLRDFGMGKRGSEEKIVEEIQYIVEEFGKFEGKAFDTTQPVNNAVSNIISSIVYGSRFEYSDP---QFKEMVNRANENVRIGGSAPIRLYNVFPWIGPFLKSKRKLERNTEKNRKEINGIISSLQETL-HPDDRRGFIDSFLVRKQSDEKSGQKNSRFNDKNLLSTVLNLFVAGTDTTGTTLRWGLLLMAKNPHIQDRVHEEIDRVIGGRQVV-VEDRKSLPYTDAVIHEIQRCANIVPMSLPHVTSCDVHFNGFFIKKGTTVYPLLTSVLRDESEWESPQTFNPDHFLDK----QGRFAKKDAFMPFSAGRRVCLGESLARMELFLFFTSLLQHFR 440          

Query:  271 AKTYGEIFKFKLGNRELVIINSSKILFKTLKDQGVNFSGRQQNDLIKYITHDCGIVFKEKEWWSTQRSFALKVLRDFGLGKQRSIEIVNNECSILLQELEETSGKNICTKSCFPSVTVNIIAKLLMNMRFEKNSSEFFEFRKIIEQTTHN-RSFLVILFQIYTLPHFTIPFIARFSGLRNHIDAVHNFVINIINERKKTFSHENEGQDFIDMFLIEKHKLESENVKNHTFTDWQLIRMVVELFGAGFESTSTTLSWAMVLLARHTEIQDKVHQEIINLIGVDKIPDLNNKKFLHYTQAVMDEILRISTVAPLAVPHRVFNDAEVEGFYIPKDSTIFTNLYACHRDEKVWEKPFDFYPEHFLTKLDNGEMKYTPREELVPFSTGKRQCPGESLARLEYFVFLTSILQKFK 1494
            AKTYG +FK   G +++V++   K + + L +    F  R+   L K ++ + GI+F   E W   R FAL  LRDFG+GK+ S E +  E   +++E  +  GK   T     +   NII+ ++   RFE +     +F++++ +   N R       ++Y +  +  PF+     L  + +     +  II+  ++T  H ++ + FID FL+ K   E    KN  F D  L+  V+ LF AG ++T TTL W ++L+A++  IQD+VH+EI  +IG  ++  + ++K L YT AV+ EI R + + P+++PH    D    GF+I K +T++  L +  RDE  WE P  F P+HFL K    + ++  ++  +PFS G+R C GESLAR+E F+F TS+LQ F+
Sbjct:   43 AKTYGSVFKVYFGPKKVVVLAGYKTVKQALVNHAEEFGEREIGKLFKNLSEEHGILFSNGENWREMRRFALTNLRDFGMGKRGSEEKIVEEIQYIVEEFGKFEGKAFDTTQPVNNAVSNIISSIVYGSRFEYSDP---QFKEMVNRANENVRIGGSAPIRLYNVFPWIGPFLKSKRKLERNTEKNRKEINGIISSLQETL-HPDDRRGFIDSFLVRKQSDEKSGQKNSRFNDKNLLSTVLNLFVAGTDTTGTTLRWGLLLMAKNPHIQDRVHEEIDRVIGGRQVV-VEDRKSLPYTDAVIHEIQRCANIVPMSLPHVTSCDVHFNGFFIKKGTTVYPLLTSVLRDESEWESPQTFNPDHFLDK----QGRFAKKDAFMPFSAGRRVCLGESLARMELFLFFTSLLQHFR 442          

Query:  100 NVLISIFLVIILYFLSRKFSTNPIPIGLRPLQ---GPSGWPLVGNLFSIKEPLWSIFYKHAKTYGEIFKFKLGNRELVIINSSKILFKTLKDQGVNFSGRQQNDLIKYITHDCGIVFKE-KEWWSTQRSFALKVLRDFGLGKQRSIEIVNNECSILLQELEETSGKNICTKSCFPSVTVNIIAKLLMNMRFEKNSSEFFEFRKIIEQTTHNRSFLV-ILFQIYTLPHFTIPFIARFSGLRN----HIDAVHNFVINIINERKKTFSHENEGQDFIDMFLIEKHKLESENVKNHTFTDWQLIRMVVELFGAGFESTSTTLSWAMVLLARHTEIQDKVHQEIINLIGVDKIPDLNNKKFLHYTQAVMDEILRISTVAPLAVPHRVFNDAEVEGFYIPKDSTIFTNLYACHRDEKVWEKPFDFYPEHFLTKLDNGEMKYTPREELVPFSTGKRQCPGESLARLEYFVFLTSILQKFKIKFNKAIDDITYEKITRGTDGTVRAPLDVDLIFEMR 1602
              LIS+ +  I++ + R      +    RPL    GP   P +GN+   K+P  ++  +  K YGE+    +G   +V ++  + + + L  QG  F+ R      K +    GI+F    ++W   R F L  LR+FGLGK    + +  E   L++  ++  G          S   NII  ++   R+E +  +F +F  ++E     +S L+  L  I+       PF+  F G +      +     F+ +II+ER  T     +    ID +L    +LE E+  N +F++  LI + ++LF AG E+TSTTL W ++ +  H EIQ + H+EI  ++G D++P + ++  L Y  AV+ EI R S + P   PH    D +   + IPK + I  N+ +   DE  W+ P++F PE+FL +    + K+   +  +PFS G R C GE+LA++E F+F  S+LQ F+  +   +   T   I + T    +AP    L   +R
Sbjct:   22 QALISLAIFCIIFLVLRAI-LQEVKATKRPLDFPPGPKVIPFLGNVSLFKKPDVAL-DEVTKQYGEVCSVMVGKISMVFVSGYQAVKEVLVHQGHEFADRPNTPFNKKVNGGLGIIFAPYGKYWMQHRRFTLSTLRNFGLGKSSIEQTIQAEVGFLIEAFKQ-KGSAFDPHYDLNSAVGNIICSMVKGKRYEYSDKQFQDFLHLVENNLQLQSGLLGTLCNIF-------PFLMDFPGPQQIIFKSMAKSKQFIRDIISERHAT-RDPIKPMCLIDAYL---SQLEKEDNPNSSFSEQSLIMLALDLFIAGAETTSTTLRWGLLYMMMHPEIQAQCHEEIDKIVGSDRLPCMEDRHSLPYLDAVIHEIQRFSNIVPFGAPHATTADVKFRQYLIPKGTIIMVNMKSVLSDENHWKTPYEFSPENFLDE----DGKFVKPDAFLPFSAGPRVCLGENLAKMELFLFFASLLQHFEFYWPDLVSAPTLGYILQIT----KAPKSYKLGLHLR 509          

Query:  103 VLISIFLVIILYFLSRK----FSTNPIPIGLRPLQGPSGWPLVGNL--FSIKEPLWSIFYKHAKTYGEIFKFKLGNRELVIINSSKILFKTLKDQGVNFSGRQQNDLIKYITHDCGIVFKE-KEWWSTQRSFALKVLRDFGLGKQRSIEIVNNECSILLQELEETSGKNICTKSCFPSVTVNIIAKLLMNMRFEKNSSEFFEFRKIIEQTTHNRS-FLVILFQIYTLPHFTIPFIARFSGLRNHIDAVHN----FVINIINERKKTFSHENEGQDFIDMFLIEKHKLESENVKNHTFTDWQLIRMVVELFGAGFESTSTTLSWAMVLLARHTEIQDKVHQEIINLIGVDKIPDLNNKKFLHYTQAVMDEILRISTVAPLAVPHRVFNDAEVEGFYIPKDSTIFTNLYACHRDEKVWEKPFDFYPEHFLTKLDNGEMKYTPREELVPFSTGKRQCPGESLARLEYFVFLTSILQKFKIKFNKAIDDITYEKITRGTDGTVRAPLDVDLIFEMR 1602
            +LIS+ L+ +++   R       +   P+G  P  GP   PL+GN+  FS K P   +  + AK YGE+    LG+  +V+++  + + + L ++G  F+ R    L   +TH+ GI      + W  QR FAL  LR+FG GK    + ++ E   L++  ++ + +    K    S   NII  LL  +R++ N+ +F +   ++E     ++  LVIL  ++       PF+ +  G    +  +H      + +I++E + T    N  +D ID +L    K E +N  N +FTD  LI +++ELF  G E+TS TL W ++ +  + +IQ + H+EI  ++G  + P + +++ L Y  AV+ EI R   + P  V H    D +   +  PK + +  NL +   D+  W+ P  F P++FL K D   +K    +  +PF  G   C GESLA++E F+F TS+LQ F+  +  +    T     R    T  +P    L   MR
Sbjct:    4 MLISLALICMVFLTVRAALQVVGSTICPVGFSP--GPKPLPLLGNITAFSCKNPHIGM-QELAKKYGEVCTIMLGSTPVVLVSGYQAVKEVLVNRGHEFADRPITPLFTKLTHNIGIALAPYGDTWKQQRGFALSTLRNFGFGKATITDKISIEARYLIETFKQETSE-FDPKFILNSAVGNIICSLLNGIRYDYNNEQFQKLTHLLEHLVQLQAEPLVILCNVF-------PFLIKLPGPWQKVFHIHTKLQCLLKDIVSEHRATKDQHNP-RDLIDSYLAHIDK-EKDN-PNRSFTDQTLILLLIELFIGGMETTSNTLCWGLLFMMMNPDIQARCHEEIDKVVGSQRPPCMKDRRSLPYLDAVIHEIQRFGNILPFGVLHPTSKDVQFNEYVFPKGTHVMVNLMSAFYDDIHWKTPHKFNPDNFLDK-DGQCIK---SDAFLPFPAGPCVCFGESLAKMELFLFFTSLLQHFEFYWPNSASPPTLAAKFR----TTLSPHPYKLGLRMR 493          

Query:  271 AKTYGEIFKFKLGNRELVIINSSKILFKTLKDQGVNFSGRQQNDLIKYITHDCGIVFKE-KEWWSTQRSFALKVLRDFGLGKQRSIEIVNNECSILLQEL-EETSGKNICTKSCFPSVTVNIIAKLLMNMRFEKNSSEFFEFRKIIEQTTHNRS-FLVILFQIYTLPHFTIPFIARFSGLRNHIDAVHN----FVINIINERKKTFSHENEGQDFIDMFLIEKHKLESENVKNHTFTDWQLIRMVVELFGAGFESTSTTLSWAMVLLARHTEIQDKVHQEIINLIGVDKIPDLNNKKFLHYTQAVMDEILRISTVAPLAVPHRVFNDAEVEGFYIPKDSTIFTNLYACHRDEKVWEKPFDFYPEHFLTKLDNGEMKYTPREELVPFSTGKRQCPGESLARLEYFVFLTSILQKFKIKFNKAIDDIT 1527
            AK YGE+    LG+  +V+++  + + + L ++G  F+ R    +   +T + GI      + W  QR FAL  LR+FG GK    + ++ E   L++   +ETS  +        +   NII  LL   R++ ++ +F +   ++E     ++  LVIL  ++       PF+ +  G    +  +H+     + +I++E + T    N  +D ID +L +  K E +N  N +FT   LI++++ELF  G E+TS TL W ++ +  + +IQ + H EI  ++G ++ P + +++ L Y  AV+ EI R   V PL V H    D +   +  PK + +  NL +   D+  W+ P  F P+HFL K  +G+   +  +  +PFS G R C GESLA++E F+F TS+LQ F+  +  ++   T
Sbjct:   67 AKKYGEVCTIMLGSTPVVLVSGYEAVKEVLVNRGHEFADRPITPIFTKLTQNIGIALAPYGDPWKQQRRFALSTLRNFGFGKATIADKISIEAKYLIETFKQETSAFD--PHLNLNNALGNIICCLLNRNRYDYDNEQFQKLTHLLEYLVQLQAEPLVILCNVF-------PFLLKLPGPWQKVFHIHSKLQCLLNDIVSEHRATKDQHNP-RDLIDSYLAQIDK-EKDN-PNSSFTHQSLIQILIELFIGGLETTSNTLRWGLLFMMMNPDIQARCHGEIDRVVGSERPPCMTDRRSLPYLDAVIHEIQRFGNVLPLGVLHATSKDVQFNDYLFPKGTHVMVNLMSALHDDIHWKTPNKFNPDHFLDK--DGQCIQS--DAFLPFSAGPRVCLGESLAKMEIFLFFTSLLQHFEFYWPNSVSPPT 476          

Query:   94 LLNVLISIFLVIILYFLSRKFSTNPIPIGLRPLQGPSGWPLVGNLFSIK-EPLWSIFYKHAKTYGEIFKFKLGNRELVIINSSKILFKTLKDQGVNFSGRQQNDLIK-YITHDCGIVFKEKEWWSTQRSFALKVLRDFGLGKQRSIEIVNNECSILLQELEETSGKNICTKSCFPSVTVNIIAKLLMNMRFEKNSSEFFEFRKII----EQTTHNRSFLVILFQIYTLPHFTIPFIARFSGLRNHID---AVHNFVINIINERKKTFSHENEGQDFIDMFLIEKHKLESENVKNHTFTDWQLIRMVVELFGAGFESTSTTLSWAMVLLARHTEIQDKVHQEIINLIGVDKIPDLNNKKFLHYTQAVMDEILRISTVAPLAVPHRVFNDAEVEGFYIPKDSTIFTNLYACHRDEKVWEKPFDFYPEHFLTKLDNGEMKYTPREELVPFST-GKRQCPGESLARLEYFVFLTSILQKFKIK 1500
            LL V+  +FL +  ++L R+    P         GP G PLVGNLF +  + L +   K ++TYG I+   LG   +V++  ++I+ + L  Q   F  R +  + K  + +  G++      W  +R F L +LR+FG+G +   E +  E   L++ +E    K     S       N+I  +    R++ N+  F +   II    E + ++ S      QI+     + P +  F G    I+    V N  I    E       + E +D++D F+    ++E     +  F+D  LI     LF AG E+TS TL W ++L+  + ++Q++V +EI  ++G ++ P   ++  + YT A + EI R + + P+A PH    D ++ G+++PK + +   +++  R++ +WE P  F P HFL    N    +  R + + FS  G R C G++LAR+E F+F T++LQ+F  +
Sbjct:   17 LLRVVAVLFLWLGFWWLRREQRGFP--------PGPRGLPLVGNLFQLDLKALPASLDKLSETYGPIYSVSLGQTRVVVLVGNEIIKEALVTQAEMFIDRPEIPVFKKSLGNYEGLLLSHGWQWRARRRFTLMMLRNFGMGTKSIEEKIAEEAEFLVRAIENKQEKPFDAHSEINKSAANVICSITFGDRYDWNNKTFVKLMDIITENVELSGNDWS------QIFN----SFPVLKYFPGPHQRINKNKVVLNAFIQARIEEHDMARIQGEPRDYLDAFI--DKRIEDSMNPDTAFSDIALINTTANLFVAGSETTSATLKWGILLMLTYPKVQEQVQEEIDRVVGSNRRPACADRACMPYTNATVHEIQRYANILPMAFPHATTCDTKLRGYFLPKGTQVIALIHSALREKSLWEAPEQFNPGHFLDIDGN----FYNRNDFMAFSAVGPRICLGKNLARMEVFLFFTALLQRFSFQ 471          

Query:  271 AKTYGEIFKFKLGNRELVIINSSKILFKTLKDQGVNFSGRQQNDLIKYITHDC-GIVFKE-KEWWSTQRSFALKVLRDFGLGKQRSIEIVNNECSILLQELEETSGKNICTKSCFPSVTVNIIAKLLMNMRFEKNSSEFFEFRKIIEQTTHNRSFLVILF---QIYTLPHFTIPFIARFSGLRNHIDAVHN-----FVINIINERKKTFSHENEGQDFIDMFLIEKHKLESENVKNHTFTDWQLIRMVVELFGAGFESTSTTLSWAMVLLARHTEIQDKVHQEIINLIGVDKIPDLNNKKFLHYTQAVMDEILRISTVAPLAVPHRVFNDAEVEGFYIPKDSTIFTNLYACHRDEKVWEKPFDFYPEHFLTKLDNGEM--KYTPREELVPFSTGKRQCPGESLARLEYFVFLTSILQKFKIKFNKAIDDIT 1527
            A+TYG ++  ++G  ++V++N+ + + + L  +  +F+GR Q      IT     I   +    W  QR  AL  L    +G  R+ EIV  E   L+++L +  G+     +       N+I  +    +++K+ +EF +    ++        LV L+    I  L  F +  +      R+ + AV       +   ++++ K + S  ++  DF+  F       E    +    T+ ++   +++ F AG E+T+T + WA+  L  H E+QD++++E+   +     P L ++  L Y  A + EILR+  VAPLA+PHR   D+ V GF+I K ST+  NL+A HRD   W+ P  F P  FL     GE   +  P   L+PF  GKR C GESLA+ E F+FL  +L++ +++   +  D++
Sbjct:   72 ARTYGAVYCLRVGGEDIVVLNNVESIKEMLIKKSADFAGRPQTYAGGKITGGGKDIALGDYSAVWRRQRRAALSALH--CVGTARTEEIVQGEAQRLVEDLTQYIGRPTDIHTDISMRVCNVICSVAFGTKYDKHDTEFLDIHCCLDS-------LVRLWGSPAIRALDCFPVLRLFPNPAWRDLMAAVRKRDEVVWRQILLHKAKPSSSPSSDMTDFLLKFTRHSRNEEESEARGGILTEERVHLSIMDTFIAGVETTATLIEWALAYLVLHPEVQDQIYEEMEQKLQPGLGPSLADRDKLLYLDATIKEILRLCPVAPLAIPHRALRDSSVGGFFICKGSTVIANLWAAHRDHAHWDNPSVFQPGRFL-----GESLERRNPASLLLPFGAGKRVCLGESLAKAEIFLFLGHVLRRLRLQPAGSPPDLS 488          

Query:  928 ESENVKNHTFTDWQLIRMVVELFGAGFESTSTTLSWAMVLLARHTEIQDKVHQEIINLIGVDKIPDLNNKKF--LHYTQAVMDEILRISTVAPLAVPHRVFNDAEVEGFYI-PKDSTIFTNLYACHRDEKVWEKPFDFYPEHFLTKLDNGEMKYTPREELVPFSTGKRQCPGESLARLEYFVFLTSILQKFKI 1497
            +   + +  FT+ ++   V     A  +++S+   W   ++A   ++  K+ +E + +   D   +LN      + YT  V+ E LR      L VP+ V  +  V   Y  PK + +   LY    D +V+E P +F PE ++      E K   +  LV F  G   C G++   + +     ++L KF +
Sbjct:  312 DDSRIYHREFTNKEISEAVFTFLFASQDASSSLACWLFQIVADRPDVLAKIREEQLAVRNNDMSTELNLDLIEKMKYTNMVIKETLRYRPPV-LMVPYVVKKNFPVSPNYTAPKGAMLIPTLYPALHDPEVYENPDEFIPERWVEGSKASEAK---KNWLV-FGCGPHVCLGQTYVMITF----AALLGKFAL 495          

Query:  196 GPSGWPLVGNLFSIKEPLWSIFYKHA---KTYGEIFKFKLGNRELVIINSSKILFKTLKDQGVN-FSGRQQNDLIKYIT----------HDCGIVFKEKEWWSTQRSFALKVLRDFGLGKQRSIEIVNNECSILLQELEETSGKNICTKSCFPSVTVNIIAKLLMNMRFEKNSSEFFEFRKIIEQTTHNRSFLVILFQIYT-LPHFTIPFIARFSGLRNHIDAVHNFVINIINERKKTFSHENEGQDFIDMFLIEKHKLESENVKNHT-FTDWQLIRMVVELFGAGFESTSTTLSWAMVLLARHTEIQDKVHQEIINLIGVDKIPDLNNKKFLHYTQAVMDEILRISTVAPLAVPHRVFNDAEVEGFYIPKDSTIFTNLYACHRDEKVWEKPFDFYPEHFLTKLDNGEMKYTPREELVPFSTGKRQCPGESLARLEYFVFLTSILQKF 1491
            GP+  PL+GNL SIK    +I ++ A   KT+G+I   +L   ++V++ S  +  + L  + +N F+GR +    +Y++          +  G+V+K K   S  R    K     G       + +  E + L  +L    G  + +K  F  + +NII   L    F+K   EF E  +++ +T    S    +   +  L HF +     F  +    D +     NI+   K+TF +EN  +D  D FL  K  +E E+ K     TD ++  M+++++ AG E+T T+L W +  L  + E+Q +V   I ++IG D+ P +++++ L Y +A++ E+LR+S   PL +PH+   D  ++G+ IPK +T+  NL+A H D + W +P  F P+ F+   ++G+ +       +PF  G+R C GESLA++E F+ +T +LQ+F
Sbjct:    4 GPTPLPLIGNLLSIKS--SNIHFELANLAKTHGDIMMIELFGMKIVVVTSGPLAREVLMGKHINDFAGRPKRFTFEYMSKGYKDIALNDYSPGLVWKRKIVHSGLR----KYFPSLG-------DTIAKELAKLEDKLNSDVGVPVDSKDEFFLLVLNIICSFLSGKAFDKEDPEFSETLELVTKTVDTLSMSASILDAFPFLIHFPLQASKNFKRIAELRDKLMG---NILTFHKETF-NENHIRDLTDAFLKAKLDIEREDKKAAGEVTDEEVALMMMDVYLAGLETTVTSLRWIIAYLMNNQEVQSRVQSRIDDVIG-DRRPLMSDRQGLPYMEALVAEVLRLSPPIPLGLPHKSILDTTIDGYTIPKGTTVLFNLWAIHHDPREWPEPDKFDPDRFIN--EDGKFEVPGDRNFLPFMAGRRVCLGESLAKMELFLIMTRLLQQF 431          

Query:  196 GPSGWPLVGNLFSIKEPLWSIFYKHA---KTYGEIFKFKLGNRELVIINSSKILFKTLKDQGVN-FSGRQQNDLIKYIT----------HDCGIVFKEKEWWSTQRSFALKVLRDFGLGKQRSIEIVNNECSILLQELEETSGKNICTKSCFPSVTVNIIAKLLMNMRFEKNSSEFFEFRKIIEQTTHNRSFLVILFQIYT-LPHFTIPFIARFSGLRNHIDAVHNFVINIINERKKTFSHENEGQDFIDMFLIEKHKLESENVKN-HTFTDWQLIRMVVELFGAGFESTSTTLSWAMVLLARHTEIQDKVHQEIINLIGVDKIPDLNNKKFLHYTQAVMDEILRISTVAPLAVPHRVFNDAEVEGFYIPKDSTIFTNLYACHRDEKVWEKPFDFYPEHFLTKLDNGEMKYTPREELVPFSTGKRQCPGESLARLEYFVFLTSILQKF 1491
            GP+  PL+GNL SIK    +I ++ A   KT+G+I   +L   ++V++ S  +  + L  + +N F+GR +    +Y++          +  G+V+K K   S  R    K     G       + +  E + L  +L    G  + +K  F  + +NII   L    F+K   EF E  + +  T    S    +   +  L HF +     F  +    D +     NI+   K+TF +EN  +D  D FL  K  +E E+ K     TD ++  M+++++ AG E+T T+L W +  L  + E+Q +V   I ++IG D+ P +++++ L Y +A++ E+LR+S   PL +PH+   D  ++G+ IPK +T+  NL+A H D + W +P  F P+ F+   ++G+ +       +PF  G+R C GESLA++E F+ +T +LQ+F
Sbjct:    4 GPTPLPLIGNLLSIKS--SNIHFELANLAKTHGDIMMIELFGMKIVVVTSGPLAREVLMGKHINDFAGRPKRFTFEYMSKGYKDIALNDYSPGLVWKRKIVHSGLR----KYFPSLG-------DTIAKELAKLEDKLNSDVGVPVDSKDEFFLLVLNIICSFLTGKAFDKEDPEFSETLEFVTMTVDTISMSASILDAFPFLIHFPLQASKNFKRIAELRDKLMG---NILTFHKETF-NENHIRDLTDAFLKAKLDIEREDKKAAEEVTDEEVALMMMDVYLAGLETTVTSLRWIIAYLMNNQEVQSRVQSRIDDVIG-DRRPLMSDRQGLPYMEALVAEVLRLSPPIPLGLPHKSILDTTIDGYTIPKGTTVLFNLWAIHHDPREWPEPDKFDPDRFIN--EDGKFEVPGDRNFLPFMAGRRVCLGESLAKMELFLIMTRLLQQF 431          

Query:  217 VGNLFSIKEPLWSIFYKHAKTYGEIFKFKLGNRELVIINSSKILFKTLKDQGVNFSGRQ--QNDLIKYITHDCGI-VFKEKEWWSTQRSFALKVLRDFGLGKQRSIEIVNNECSILLQELEETSGKNICTKSCFPSVTVNIIAKLLMNMRFEKNSSEFFEFRKIIEQTTHNRSFLVILFQIYTLPHFTIPFIARFSGLRNHIDAVHNFVINIINERKKTFSHENEGQDFIDMFLIEKHKLESEN--VKNHTFTDWQLIRMVVELFGAGFESTSTTLSWAMVLLARHTEIQDKVHQEIINLIGVDKIPDLNNKKFLHYTQAVMDEILRISTVAPLAVPHRVFNDAEVEGFYIPKDSTIFTNLYACHRDEKVWEKPFDFYPEHFLTKLDNGEMKYTPREELVPFSTGKRQCPGESLARLEYFVFLTSILQKFK 1494
            +GNL  + + +   F +  KTYG++++  LG++ L I+ S   + + L  Q  NF+GR      L   +    G+ V    E W   R      ++ +G  + R  +++ +E   L   LE ++GK             N+I   L   R++ +  EF    +I ++ +       ++  I+      +PF  +   L       +  +     E  KTF  EN  +D+ D  L  K   E E+   K H      ++  +  LF AG E+TSTTL WA++ L  + ++Q+++H+EI ++IG D  P L+ +K L   +A   E LR++ +APLA+PH+    + ++GF IP+ +T+F NL++ H D  VW+ PF F  + FL   + G+ K       +PF  G R C GE LAR E F+FL+ +LQ+F+
Sbjct:   37 IGNLNLLSKQMHLSFTELEKTYGKVYRLYLGHK-LAIVLSGDAIKEALVRQPRNFAGRPVLNPQLKSALNRGPGLTVMDYGETWKLFRKLGHSTIKVYG--ENRLQDVIKDEVLELCNRLESSAGKPFDITQQSGIAVTNVICTKLFGTRYQIDDPEFLRVYEIHDKLSRIGFGGNLVTNIFPSLASILPFSEKQRDLIQIGQERYEILERKYQEHVKTFDPENI-RDYTDALLKAKQDAEQEDKSSKEHLQESTIIMAGLATLFIAGSETTSTTLGWAVIYLLHNPDVQERLHKEIDDVIGRDAFPQLSKRKELPVLEAFTAETLRLANLAPLAIPHKARERSTLQGFEIPEGTTVFANLWSLHHDPTVWKDPFTFNLDRFLD--EEGKFKAPVGGTFLPFGAGPRVCLGEVLARSELFLFLSRMLQRFE 461          

Query:  103 VLISIFLVIILYFLSRKFSTNPIPIGLRPLQGPSGWPLVGNLFSI--KEPLWSIFYKHAKTYGEIFKFKLGNRELVIINSSKILFKTLKDQGVNFSGRQ--QNDLIKYITHDCGIVFKEKEWWSTQRSFALKVLRDFGLGKQRSIEIVNNECSILLQELEETSGKNICTKSCFPSVTVNIIAKLLMNMRFEKNSSEFFEFRKIIEQTTHNRSFLVI-----LFQIYTLPHFTIPFIARFSGLRNHIDAVHNFVINIINERKKTFSHENEGQDFIDMFLIEKHKLESENVKNHTFTDWQLIRM-VVELFGAGFESTSTTLSWAMVLLARHTEIQDKVHQEIINLIGVDKIPDLNNKKFLHYTQAVMDEILRISTVAPLAVPHRVFNDAEVEGFYIPKDSTIFTNLYACHRDEKVWEKPFDFYPEHFLTKLDNGEMKYTPREELVPFSTGKRQCPGESLARLEYFVFLTSILQKF 1491
            +LIS+ L+ I Y  SRK    P         GP+ WP++GNL  +  KE L+  F   +  YG +F+  LG++ +V++N  K ++ +L  Q   F+GR      L   +  D G V      W   +      +R  G    R  E +  E   + + L+   G+ +     F   T N+I   L   R++ +  EF    +I     HN+   V+     L  ++      +P       LR  +   +  +     E ++TF+     +D+ D+ +    KL  +N  +H  T+  +I   +   F AG E+T++TLSW++V L   +++Q+++H E+ ++IG  ++P L++KK L   +A   E LR+S + PL +PH+   D  + G  IPK +T+  NL++ H D   W+ PF F    F   L++G  +    +  +PFS G R C GE LAR E F+FL  +LQKF
Sbjct:    9 LLISLALIYIFY--SRKERLPP---------GPAPWPIIGNLDLLIRKEALYKTFTNLSHKYGGVFRLYLGSKPVVVLNG-KAIYDSLARQPSVFAGRPTLPPSLDFGMDPDYG-VLDYGPLWKFYKKLGHSAVRVHG--TDRLNEAIRVEVDEVCRRLDSLDGQPVDISKEFGIATTNVICARLFGSRYDVHDPEFLRIYEI-----HNKISRVVMSSRSLSDVFPFLVNILPESKERRELRELLQERYTIIWRKYKEHEQTFT-PGVIRDYTDLLI--DAKLSEKN--SHKLTENGIISTGLASQFLAGSETTASTLSWSVVYLLNDSDVQERIHNELDDVIGKGQLPQLSHKKKLPVLEAFTAETLRLSCIGPLGMPHKTTRDTFLRGHAIPKGTTVVPNLWSLHHDSTEWKDPFKFDINRF---LEDGVFRAPANDAYLPFSAGPRVCLGEELARSELFLFLARLLQKF 453          

Query:  193 QGPSGWPLVGNLFSIK-EPLWSIFYKHAKTYGEIFKFKLGNRELVIINSSKILFKTLKDQGVN-FSGRQQNDLIKYITHDC-----GIVFKEKEWWSTQRSFALKVLRDFGLGKQRSIEIVNNECSILLQELEETSGKNICTKSCFPSVTVNIIAKLLMNMRFEKNSSEFFEFRKIIEQTTHNRSFLVILFQIYTLPHFTIPFIARFSGLRNHIDAVHNFVINIINERKKTFSHENEGQDFIDMFLIEKHKLESENVKN-HTFTDWQLIRMVVELFGAGFESTSTTLSWAMVLLARHTEIQDKVHQEIINLIGVDKIPDLNNKKFLHYTQAVMDEILRISTVAPLAVPHRVFNDAEVEGFYIPKDSTIFTNLYACHRDEKVWEKPFDFYPEHFLTKLDNGEMKYTPREELVPFSTGKRQCPGESLARLEYFVFLTSILQKF 1491
             GP   PL+GNL +I    +     K  K YG++F  ++    +V INS     + +  + ++ F+GR +     YIT +C     G   +   W   +R      LR +     R   I+  +       ++ + G  + ++  F  + +NII   +    +  +  EF + ++    +        IL     L HF +     F G RN  D V +    I    K+TF  E   +D  D  L  K ++E E+ K     TD  +I M+ ++FG G EST ++L W +  L  H E+Q +   E+ ++IG +K P L +++ L Y +AV+ E LR+ +  PLA+PH+   D       IPK +T+  NL+A HRD K W  P +FYP  F+    NGE +   +   +PFS G+R C G+S+A+ E F+ +  ++Q++
Sbjct:    9 DGPKPLPLIGNLHNIAGSEIHLAVTKLVKDYGDVFTLRILGESIVFINSGAAAKEAMLGKHMDDFAGRPKKFTFDYITRNCQDIILGDYSRALNW---RRKVFHSALRMYA---PRFDNIIREQIVAFESRMDASEGLPVDSRDEFALLILNIICSFVCGKTYSLDDPEFKKIKQFNIYSAEVPVATCILNIFPWLIHFPLKSSRLFKGFRNTRDEVLD---KIFLAHKETF-QEGNIRDLADALLQAKIEIEREDKKAVGMVTDDHVIMMLSDIFGGGLESTISSLRWCVAFLIYHPEVQARAQAELDDVIG-EKFPTLADREKLPYIEAVIAETLRMGSNVPLAIPHKAIRDTAFRERAIPKGTTVLLNLWAIHRDPKEWSNPEEFYPGRFINS--NGEFEVPSKLSFLPFSLGRRVCVGQSVAKAELFLIVARMIQRY 436          

Query:  106 LISIFLVIILYFLSRKFSTNPIPIGLRPLQGPSGWPLVGNLFSI--KEPLWSIFYKHAKTYGEIFKFKLGNRELVIINSSKILFKTLKDQGVNFSGRQQNDLIKYITHDCGIVFKEKEWWSTQRSFALKVLRDFGLGKQRSIEIVNNECSILLQELEETSGKNICTKSCFPSVTVNIIAKLLMNMRFEKNSSEFFEFRKIIEQTTHNRSFLVILFQIYTLPHFT-IPFIARFSGLRNHIDAVHNFVINIINERKKTFSHENEG------QDFIDMFLIEKHKLESENVKNHTFTDWQLIRMVVELFGAGFESTSTTLSWAMVLLARHTEIQDKVHQEIINLIGVDKIPDLNNKKFLHYTQAVMDEILRISTVAPLAVPHRVFNDAEVEGFYIPKDSTIFTNLYACHRDEKVWEKPFDFYPEHFLTKLDNGEMKYTPREELVPFSTGKRQCPGESLARLEYFVFLTSILQKF 1491
            L+ I  V++LYF+S +F  N    G  P  GP   P++GNL  I  K P +    + +KTYG +F    G  ++V++   K +   L +    F  R    +I+ +    G+++   + W   R FAL  LRDFG+GK+   + +  EC  LL+  ++  G    T         NII  ++   RFE +  +F     ++++T  N    + L    TL  +  +P++ ++   R     VH        + +  FSH  E       + F+D FL++   LE   V N  F D  L+  V+ LF AG E+TSTTL W ++L+A++ +IQD+V  E+  +IG D++  ++++K L +T AV+ EI R++++ P A+PH+   D   +G++I K +T+F  L +   D   WEKP  FYP HFL K    + K+  RE  +PFS G+R C GESLAR+E F+F T++LQ F
Sbjct:   15 LVGILAVLVLYFIS-QFIFNSEQHGQEP-PGPRPLPIIGNLMQIDLKRP-YKTLEEFSKTYGPVFTVFFGGEKVVVLAGYKTVKNALVNHDEEFGERAIPPIIQELNKGLGVLWSNGDIWRDIRRFALTNLRDFGMGKKACEDKITEECQYLLEVFKKFKGNAFDTTKPLNYAVSNIICSMVYGSRFEYDDPKF---TSMVDRTNRN----IQLSGSPTLQAYNMVPWLFKWVASRRE---VHECAAANRKQNQSIFSHLKETLNPQMCRGFVDAFLVKGQTLEKSGVTNSAFNDENLLMTVIHLFAAGTETTSTTLRWGLLLMAKYPKIQDQVQDELRRVIG-DRMVQVSDRKNLPFTDAVIHEIQRLASIVPTALPHKTSKDVTFQGYFIKKGTTVFPLLTSVLHDANEWEKPHTFYPAHFLDK----DGKFVKREAFIPFSAGRRICLGESLARMELFMFFTTLLQNF 467          

Query:  196 GPSGWPLVGNLFSIKEPLWSIFY-KHAKTYGEIFKFKLGNRELVIINSSKILFKTLKDQGVNFSGRQQNDLIK--YITHDCGIVFKEKEWWSTQRSFALKVLRDFGLGKQRSIEIVNNECSILLQELEETSGKNICTKSCFPSVTVNIIAKLLMNMRFEKNSSEFFEFRKIIEQTTH-NRSFLVILFQIYTLPHFTIPFIARFSGLRNHIDAVHN-----------FVINIINERKKTFSHENEGQDFIDMFLIEKHKLESENVKNHTFTDWQLIRMVVELFGAGFESTSTTLSWAMVLLARHTEIQDKVHQEIINLIGVDKIPDLNNKKFLHYTQAVMDEILRISTVAPLAVPHRVFNDAEVEGFYIPKDSTIFTNLYACHRDEKVWEKPFDFYPEHFLTKLDNGEMKYTPREELVPFSTGKRQCPGESLARLEYFVFLTSILQKFKIKFNKAIDDITYEKITRGTDGTVRAP 1572
            GP G P VGN  +I      I++ K A++YG +F  +LG++  V ++  K++ + L  Q  NF  R  +++    Y  +  G+ F   E W  QR FAL  LR FGLGK    + +  E   L Q++E   G        F +   NII +L+M  RF+ + + F    K I +      S   IL++              F GL  H+   HN           F+   I   K+     N  +D+ID F+IE  K ++ ++    F D  L    ++LF AG E+TSTTL WA++ L +H ++Q KV QEI  +IG +++P + ++  L YT AV+ EI RI  + PL        D  + G++IPK + +   L +   D+  WE P  F PEHFL    + + K+  +E  +PFS GKR C GE LAR+E F+FL  +LQKF     + +     E  T G  GT R P
Sbjct:   40 GPLGLPFVGNFLTIDGKHPHIYFSKMAESYGNVFSVRLGSQATVFVSGYKMVKEALVTQAENFVDRPFSEIGGRFYEGNSNGLFFSNGEKWKKQRRFALSTLRTFGLGKNTMEQSICEEIRHLQQQIENEKGGPFSPAGLFNNAVSNIICQLVMGKRFDYDDNNFQVMMKYISEAVQLEGSIWGILYE-------------SFPGLMKHLPGSHNKIFRNYKIVQDFLAQEIKIHKQDLDPNNP-RDYIDSFIIEMEKHQNSDL---GFNDANLAFCSLDLFVAGTETTSTTLMWALIYLIKHPDVQVKVQQEIDRVIGQNRLPSMADRPNLPYTDAVVHEIQRIGNIVPLNGLRVAAKDTTLGGYFIPKGTALMPMLTSVLFDKTEWETPDTFNPEHFL----DADGKFVKKEAFLPFSAGKRVCLGEGLARMELFLFLVGLLQKFSFSVPEGV-----ELSTEGITGTTRVP 487          

Query:  160 TNPIPIGLRPLQGPSGWPLVGNLFSIKEPLWSIFYKH-AKTYGEIFKFKLGNRELVIINSSKILFKTLKDQGVNFSGRQQNDLIKYITHDCGIVFKEKEWWSTQRSFALKVLRDFGLGKQRSIEIVNNECSILLQELEETSGKNICTKSCFPSVTVNIIAKLLMNMRFEKNSSEFFE-FRKIIEQTTHNRSFLVILFQIYTLPHFTIPFIARFSGLRNHIDAVHNFVINIINERKKTFSHENEGQDFIDMFLIEKHKLESENVKNHTFTDWQLIRMVVELFGAGFESTSTTLSWAMVLLARHTEIQDKVHQEIINLIGVDKIPDLNNKKFLHYTQAVMDEILRISTVAPLAVPHRVFNDAEVEGFYIPKDSTIFTNLYACHRDEKVWEKPFDFYPEHFLTKLDNGEMKYTPREELVPFSTGKRQCPGESLARLEYFVFLTSILQKFKIKFNKAIDDITYEKITRGTDGTVRAP 1572
            TN  P    P  GP   P +G+L  I+  +  + +K  A  YG +F   +   + V++N +K+L + L  +G +F  R Q  L   +  + GIV      W  QR FAL  LR+FGLGK+   + +  EC  + Q   E  GK    +    S   NII  L+   RFE +  E+ +  + + E      SF  + + ++  P     F      L   +D + +FV   I E K+        +D+ID FLIE  K + E+     F    L    ++LFGAG E+T+TTL W ++ +  + +IQ++VH EI  +IG  + P + +K+ + YT AV+ EI R+  + P+ V      D  ++ + IPK + I   L+    DE VWE P  F P+HFL    N +  +  RE   PF  GKR C GE LAR+E F+F TS LQ+F   F+ A  +   +    G  GT+R+P
Sbjct:   33 TNRKPKNFPP--GPRSLPFIGDLHRIRPTILHLQFKEFAAKYGNVFSLNIFGGKTVVLNGTKLLKEALIQKGDDFVDRPQIPLFSDLIENKGIVMTNGIQWKHQRRFALHTLRNFGLGKKTMEKYIQEECHYITQAFAEHQGKPFDAQPLLNSAVSNIICCLVFGERFEYSDKEYQQILQDLTEVVKLQGSFSALAYNVF--PWLMKRFPGPLQKLFTLVDKIMDFVKIKIEEHKENLDPACP-KDYIDSFLIEMEKNQGEDF---GFDIKNLCACTLDLFGAGSETTTTTLYWGLLFMIHYPDIQEEVHAEIDAVIGSSRQPSMADKENMPYTDAVIHEIQRMGDIVPIGVARMASRDTMLDNYTIPKGTMIMPALHTVLHDESVWETPHSFNPQHFL----NQDGTFKKREAFFPFGAGKRVCLGEQLARMELFLFFTSFLQRF--SFSTAGGE---KPPLEGRMGTIRSP 488          

Query:  259 FYKHAKTYGEIFKFKLGNRELVIINSSKILFKTLKDQGVNFSGRQQNDLIKYITHDCGIVFKEKEWWSTQRSFALKVLRDFGLGKQRSIEIVNNECSILLQELEETSGKNICTKSCFPSVTVNIIAKLLMNMRFEKNSSEFFEFRKIIEQTTH-NRSFLVILFQIYTL-------PHFTIPFIARFSGLRNHIDAVHNFVINIINERKKTFSHENEGQDFIDMFLIEKHKLESENVKNHTFTDWQLIRMVVELFGAGFESTSTTLSWAMVLLARHTEIQDKVHQEIINLIGVDKIPDLNNKKFLHYTQAVMDEILRISTVAPLAVPHRVFNDAEVEGFYIPKDSTIFTNLYACHRDEKVWEKPFDFYPEHFLTKLDNGEMKYTPREELVPFSTGKRQCPGESLARLEYFVFLTSILQKFKIKFNKAIDDI 1524
            F K A  YG+++  + G R  V++N  K L + L  +G +   R    L   I    G++F     W+ QR FAL  LR FG GK+    ++ NE +   +EL+   G+ +       +   NII  L+   RF     +F +   + ++      S    L+  +TL       PH T+  I R          V +F+   + E KK++   ++ +D+ID +L E  K + +  +  TF +  LI  V++LF AG E+TSTTL WA + +A++ EIQ+KV  EI  +IG  + P + ++  L YT AV+ E+ RI  + PL++PH    D ++ GF IPK   I  NL +   DEK WE P  F P HFL K    + K+  R   +PFS GKR C GE+LAR+E F+F TS +Q F       ++ +
Sbjct:   89 FSKLAAEYGDLYSLRFGQRWTVVLNGHKALKEALVTKGDSVVDRPHLPLQDEIAKGLGVIFSNGANWTEQRRFALSTLRYFGFGKKSLEPVILNEFAHCAEELKRFKGEPLDPHLIINNTVSNIICHLVFGHRFNYGDKKFKKLMLLFDRALQIEASIWAQLYNSFTLIMRCLPGPHKTLQHIWR---------EVQDFIGEELKEHKKSWD-PSDARDYIDFYLTEIQKTKGQ--EGSTFDEENLIMCVLDLFVAGSETTSTTLRWAFLYMAKYPEIQEKVQAEIHKVIGKSRPPCMEDRAELPYTDAVIHEVQRIGNIVPLSLPHATNKDVQLGGFTIPKGVLIIPNLTSVLFDEKEWETPHAFNPGHFLNK----DGKFVKRGAFIPFSAGKRLCLGENLARMELFLFFTSFMQHFSFSMPAGVEPV 502          

Query:  217 VGNLFSIKEPLWSIFY-KHAKTYGEIFKFKLGNRELVIINSSKILFKTLKDQGVNFSGRQQNDLIK--YITHDCGIVFKEKEWWSTQRSFALKVLRDFGLGKQRSIEIVNNECSILLQELEETSGKNICTKSCFPSVTVNIIAKLLMNMRFEKNSSEFFEFRKIIEQTTH-NRSFLVILFQIYT--LPHFTIPFIARFSGLRNHIDAVHNFVINIINERKKTFSHENEGQDFIDMFLIEKHKLESENVKNHTFTDWQLIRMVVELFGAGFESTSTTLSWAMVLLARHTEIQDKVHQEIINLIGVDKIPDLNNKKFLHYTQAVMDEILRISTVAPLAVPHRVFNDAEVEGFYIPKDSTIFTNLYACHRDEKVWEKPFDFYPEHFLTKLDNGEMKYTPREELVPFSTGKRQCPGESLARLEYFVFLTSILQKFKIKFNKAIDDITYEKITRGTDGTVRAP 1572
            VGNL S+      I++ K A+TYG +F  + G+   V ++  K++ + L  Q  NF  R  + +    Y     GI     E W  QR FAL  LR FGLGK    + +  E   L  E+E   G+       F +   NI+ +L+M  RF+ N  +F    K + +      S   +L++ +   + H   P    F       D + +F+   I   KK     N  +D+ID FLIE  K ++ ++    F +  L    ++LF AG E+TSTTL WA++ L +H ++Q KV QEI  +IG +++P + ++  L YT AV+ EI R   + PL        D  + G++IPK + +   L +   D+  WE P  F PEHFL    + + K+  +E  +PFS GKR C GE LAR+E F+FL  +LQKF     + +     E  T G  GT R P
Sbjct:   47 VGNLLSVDGKHPHIYFTKLAETYGNVFSVRFGSETSVFVSGYKMVKEALVTQAENFVDRPYSPMATRFYQGPTNGIFMSNGEKWKKQRRFALSTLRTFGLGKNTMEQCICEEIRHLQAEIESEKGQLFTPTGLFNNAVSNIVCQLVMGKRFDYNDHDFHTMIKYLSEVLRLEGSVWGLLYEAFPGLMKHLPGPHNEMFK----DFDILRDFLDQEIKMHKKDLDRNNP-RDYIDSFLIEMEKHQNSDLG---FNEANLAFCSLDLFLAGTETTSTTLMWALIYLIKHPDVQVKVQQEIDRVIGQNRLPSMADRPNLPYTDAVIHEIQRFGNIVPLNGLRVAAKDTTLGGYFIPKGTALMPMLTSVLFDKTEWETPDTFNPEHFL----DADGKFVKKEAFLPFSAGKRVCLGEGLARMELFLFLVGLLQKFSFSVPEGV-----ELSTEGITGTTRVP 487          

Query:   91 TLLNVLISIFLVIILYFLSRKFSTNPIPIGLRPLQGPSGWPLVGNLFSIKEPLWSIFYKHAKTYGEIFKFKLGNRELVIINSSKILFKTLKDQGVNFSGRQQNDLIKYITHDCGIVFKEKEWWSTQRSFALKVLRDFGLGKQRSIEIVNNECSILLQELEETSGKNICTKSCFPSVTVNIIAKLLMNMRFEKNSSEFFEFRKIIEQTTHNRSFLVILFQIYTLPHFTIPFIARFSGLRNHIDAVHNFVINIINERKKTFSHENEGQDFIDMFLIEKHKLESENVKNHTFTDWQLIRMVVELFGAGFESTSTTLSWAMVLLARHTEIQDKVHQEIINLIGVDKIPDLNNKKFLHYTQAVMDEILRISTVAPLAVPHRVFNDAEVEGFYIPKDSTIFTNLYACHRDEKVWEKPFDFYPEHFLTKLDNGEMKYTPREELVPFSTGKRQCPGESLARLEYFVFLTSILQKFKIKFNKAIDDITYEKITRGTDGTVRAPLDVDLIFEMRF 1605
            TLLNVLISIFLVIILYFLSRKFSTNPIPIGLRPLQGPSGWPLVGNLFSIKEPLWSIFYKHAKTYGEIFKFKLGNRELVIINSSKILFKTLKDQGVNFSGRQQNDLIKYITHDCGIVFKEKEWWSTQRSFALKVLRDFGLGKQRSIEIVNNECSILLQELEETSGKNICTKSCFPSVTVNIIAKLLMNMRFEKNSSEFFEFRKIIEQTTHNRSFLVILFQIYTLPHFTIPFIARFSGLRNHIDAVHNFVINIINERKKTFSHENEGQDFIDMFLIEKHKLESENVKNHTFTDWQLIRMVVELFGAGFESTSTTLSWAMVLLARHTEIQDKVHQEIINLIGVDKIPDLNNKKFLHYTQAVMDEILRISTVAPLAVPHRVFNDAEVEGFYIPKDSTIFTNLYACHRDEKVWEKPFDFYPEHFLTKLDNGEMKYTPREELVPFSTGKRQCPGESLARLEYFVFLTSILQKFKIKFNKAIDDITYEKITRGTDGTVRAPLDVDLIFEMRF
Sbjct:    3 TLLNVLISIFLVIILYFLSRKFSTNPIPIGLRPLQGPSGWPLVGNLFSIKEPLWSIFYKHAKTYGEIFKFKLGNRELVIINSSKILFKTLKDQGVNFSGRQQNDLIKYITHDCGIVFKEKEWWSTQRSFALKVLRDFGLGKQRSIEIVNNECSILLQELEETSGKNICTKSCFPSVTVNIIAKLLMNMRFEKNSSEFFEFRKIIEQTTHNRSFLVILFQIYTLPHFTIPFIARFSGLRNHIDAVHNFVINIINERKKTFSHENEGQDFIDMFLIEKHKLESENVKNHTFTDWQLIRMVVELFGAGFESTSTTLSWAMVLLARHTEIQDKVHQEIINLIGVDKIPDLNNKKFLHYTQAVMDEILRISTVAPLAVPHRVFNDAEVEGFYIPKDSTIFTNLYACHRDEKVWEKPFDFYPEHFLTKLDNGEMKYTPREELVPFSTGKRQCPGESLARLEYFVFLTSILQKFKIKFNKAIDDITYEKITRGTDGTVRAPLDVDLIFEMRF 507          

Query:  103 VLISIFLVIILYFLSRKFSTNPIPIGLRPLQGPSGWPLVGNLFSIKEPLWSIFYKHAKTYGEIFKFKLGNRELVIINSSKILFKTLKDQGVNFSGRQQNDLIKYITHDCGIVFKEKEWWSTQRSFALKVLRDFGLGKQRSIEIVNNECSILLQELEETSGKNICTKSCFPSVTVNIIAKLLMNMRFEKNSSEFFEFRKIIEQTTHNRSFLVILFQIY----TLPHFTIPFIARFSGLRNHIDAVHNFVINIINERKKTFSHENEGQDFIDMFLIEKHKLESENVKNHTFTDWQLIRMVVELFGAGFESTSTTLSWAMVLLARHTEIQDKVHQEIINLIGVDKIPDLNNKKFLHYTQAVMDEILRISTVAPLAVPHRVFNDAEVEGFYIPKDSTIFTNLYACHRDEKVWEKPFDFYPEHFLTKLDNGEMKYTPREELVPFSTGKRQCPGESLARLEYFVFLTSILQKFKIKFNKAIDDITYEKITRGTDGTVRAPLDVDLIFEMR 1602
            VLI I L I LYF+ + F        L  LQGP+GWPL+GN+ S  EPLW + YK++K YG +FK+ +G R++VI++SSK+LFKTLK+QG NFSGR QN LIK  T + GI+F EKEWW+TQRSFALKVLRDFG GKQRS EIV+NEC ILL+++EE  GK +  +S FP  TVN+IAKL+MNMRFE +S +F E  K+IE+   N +F++ LFQ+Y     +P F  PF+  +SG          F+ NII++ KK F+ ENEG+DFID+FL E+HKL  E VKNHTFTD QLIR+V+ELF AG+E+TSTTLSW+M+LLA+H  IQ+KV+QEI++L+G +K+P+  +KK L YTQAVMDEILR+STV PL++ HRVF + EV+G YIPKDS IF NL+ACHRDE VWEKPF+FYPEHFL   ++G++KYTPR+ELVPFS GKRQC GE LAR+E+F+FLT I+QKFKI+F   I +  + KITRGTDG +RAPL  D++FE+R
Sbjct:    5 VLIFITLGIALYFIKKFFFNQSASKNLNLLQGPTGWPLIGNINSFNEPLWMVLYKYSKHYGSLFKYTMGRRDIVILSSSKMLFKTLKEQGNNFSGRFQNFLIKARTRNSGILFTEKEWWATQRSFALKVLRDFGFGKQRSQEIVSNECMILLKDIEEECGKVVSARSLFPKATVNVIAKLVMNMRFESDSKDFTELTKLIEKAIQNNNFILTLFQMYPILDNMP-FIAPFLLWWSGRNKTAKITSKFINNIIDDHKKRFNIENEGEDFIDIFLKEQHKLNEEKVKNHTFTDQQLIRVVLELFFAGYETTSTTLSWSMLLLAKHPNIQEKVYQEIVDLLGTEKLPNFADKKCLQYTQAVMDEILRVSTVVPLSISHRVFENTEVDGVYIPKDSIIFPNLFACHRDENVWEKPFEFYPEHFLNINNSGQLKYTPRDELVPFSIGKRQCLGEGLARIEFFIFLTGIIQKFKIRFENEISEEEFAKITRGTDGGIRAPLSSDVVFELR 507          

Query:   91 TLLNVLISIFLVIILYFLSRKFSTNPIPIGLRPLQGPSGWPLVGNLFSIKEPLWSIFYKHAKTYGEIFKFKLGNRELVIINSSKILFKTLKDQGVNFSGRQQNDLIKYITHDCGIVFKEKEWWSTQRSFALKVLRDFGLGKQRSIEIVNNECSILLQELEETSGKNICTKSCFPSVTVNIIAKLLMNMRFEKNSSEFFEFRKIIEQTTHNRSFLVILFQIYTLPHFTIPFIA----RFSGLRNHIDAVHNFVINIINERKKTFSHENEGQDFIDMFLIEKHKLESENVKNHTFTDWQLIRMVVELFGAGFESTSTTLSWAMVLLARHTEIQDKVHQEIINLIGVDKIPDLNNKKFLHYTQAVMDEILRISTVAPLAVPHRVFNDAEVEGFYIPKDSTIFTNLYACHRDEKVWEKPFDFYPEHFLTKLDNGEMKYTPREELVPFSTGKRQCPGESLARLEYFVFLTSILQKFKIKFNKAIDDITYEKITRGTDGTVRAPLDVDLIFEMR 1602
            T+  V++ I L + +YFLS+  +   IP GL+PLQGPSGWPL+GNLF+IKEPLWS  YK    YG +FKF +G R++V+I+S+KIL K LK++G+ FSGR +N +   + H+ GI+F + EWW+TQRSFALKVL+DFG GKQRS EI+++EC+ LL+E+EE+ GK I  +S FP  TVN+IAKL MNMRFE+++  F      +E+   N++F+V +  +Y +     P IA    RFSG     + +H     II E KK F+ ENEG+DFIDMFL EK++L++E V NHTFTDWQL+R++ ELF AG+E+TSTTL+W M+L+A++ EIQDKVH+EI+N+IG ++IP++++KK L YTQAVMDEI R+++V PL++PHR+  ++E+ G +IPK+S IF NLYACHRD +VW++PF+FYPEHFLT+  NG +KY+P +ELVPFS GKRQC GE+LAR+E+F+F TSI+Q+FK+KF K I    Y K+T GTDGT+RAPL  D++FE+R
Sbjct:    3 TIFEVIVVIALALPIYFLSKLMTRPSIPKGLKPLQGPSGWPLIGNLFTIKEPLWSFLYKQTFKYGPLFKFTMGCRDIVVISSNKILSKALKEKGIPFSGRWKNIIAITLVHNSGILFTDGEWWATQRSFALKVLKDFGFGKQRSTEIISHECAFLLKEIEESCGKVISARSLFPKCTVNVIAKLAMNMRFERDTPNFKFLTANVERVAQNKNFIVTILLMYPILE-EYPRIAKLLLRFSGREQEFEEMHAHFRAIIEEHKKRFNVENEGEDFIDMFLREKYELDNEKVLNHTFTDWQLVRVIFELFVAGYETTSTTLTWTMILMAKNLEIQDKVHKEIVNIIGSERIPNVSDKKSLPYTQAVMDEIFRVTSVVPLSLPHRLLENSEINGTFIPKNSIIFPNLYACHRDAEVWKRPFEFYPEHFLTEESNGSIKYSPMDELVPFSIGKRQCLGEALARMEFFIFFTSIMQRFKVKFEKEISVDAYAKMTMGTDGTIRAPLSSDVVFEIR 509          

Query:  118 FLVIILYFLSRKFSTNPIPIGLRPLQGPSGWPLVGNLFSIKEPLWSIFYKHAKTYGEIFKFKLGNRELVIINSSKILFKTLKDQGVNFSGRQQNDLIKYITHDCGIVFKEKEWWSTQRSFALKVLRDFGLGKQRSIEIVNNECSILLQELEETSGKNICTKSCFPSVTVNIIAKLLMNMRFEKNSSEFFEFRKIIEQTTHNRS---FLVILFQIYTLPHFTIPFIARFSGLRNHIDAVHNFVINIINERKKTFSHENEGQDFIDMFLIEKHKLESENVKNHTFTDWQLIRMVVELFGAGFESTSTTLSWAMVLLARHTEIQDKVHQEIINLIGVDKIPDLNNKKFLHYTQAVMDEILRISTVAPLAVPHRVFNDAEVEGFYIPKDSTIFTNLYACHRDEKVWEKPFDFYPEHFLTKLDNGEMKYTPREELVPFSTGKRQCPGESLARLEYFVFLTSILQKFKIKFNKAIDDITYEKITRGTDGTVRAPLDVDLIFEMR 1602
            F++I LYFL       PIP GL+ +   SG P++G +  I+ P+     K  +  G IF+ KLG R++V++N+ +++ K L D   NFSGR     IK ITHD GI+FK+ + W+TQRSF LKVLRDFGLGK +SIEIV NEC   L EL+  SG+ +      P  T NII++ +MN RF ++        + I  +T N+     ++++F  +         I   +        + N+    I E +      +EG+D +D FLI++H+L+       +F DWQLIR  VELF AG+E+TSTTL+W  + ++++ +IQ+KVH+EI  +IG +++P +N+KK L+YTQAVMDE+LR+S+VAP+ + HR F+DA + GFYIPKDS IF NLYACH D ++WE P  FYPEHFL+   NG  KY PREEL+PFS GKRQC GESLAR EYF+F  S++Q+F+I F + I +  Y +   G +G +R     + +F+ R
Sbjct:    9 FILIFLYFLYWVCRKPPIPKGLKEIPMESGLPIIGAIHKIEPPMHHYLLKLGRKLGPIFRIKLGMRKIVVLNNYEMIKKALIDDANNFSGRWSQRFIKEITHDSGIIFKDGKIWATQRSFILKVLRDFGLGKSKSIEIVQNECFNFLDELDTLSGQIVDFSELIPIYTTNIISRFIMNKRFTRDDPNIQLIEETINNSTKNKDIIQLILLMFPCFDNSSLICQLIYLLTSKWKSFVKIQNYFGEEIEEHRTNLDLTSEGEDLMDRFLIKQHELKQSTGNVESFVDWQLIRTSVELFIAGYETTSTTLNWCCLFMSKYPDIQEKVHKEISEIIGKERLPTMNDKKALNYTQAVMDEVLRLSSVAPMGLIHRTFDDANINGFYIPKDSLIFPNLYACHMDPEIWESPTTFYPEHFLSLDSNGISKYQPREELIPFSVGKRQCLGESLARSEYFIFFVSMVQRFQISFAEEISEDKYSQTIIGNEGVIRTSDIKNFLFKRR 506          

Query:  118 FLVIILYFLSRKFSTNPIPIGLRPLQGPSGWPLVGNLFSIKEPLWSIFYKHAKTYGEIFKFKLGNRELVIINSSKILFKTLKDQGVNFSGRQQNDLIKYITHDCGIVFKEKEWWSTQRSFALKVLRDFGLGKQRSIEIVNNECSILLQELEETSGKNICTKSCFPSVTVNIIAKLLMNMRFEKNSSEFFEFRKIIEQTTHNRS---FLVILFQIYTLPHFTIPFIARFSGLRNHIDAVHNFVINIINERKKTFSHENEGQDFIDMFLIEKHKLESENVKNHTFTDWQLIRMVVELFGAGFESTSTTLSWAMVLLARHTEIQDKVHQEIINLIGVDKIPDLNNKKFLHYTQAVMDEILRISTVAPLAVPHRVFNDAEVEGFYIPKDSTIFTNLYACHRDEKVWEKPFDFYPEHFLTKLDNGEMKYTPREELVPFSTGKRQCPGESLARLEYFVFLTSILQKFKIKFNKAIDDITYEKITRGTDGTVRAPLDVDLIFEMR 1602
            F++I LYFL       PIP GL+ +   SG P++G +  I+ P+     K  +  G IF+ KLG R++V++N+ +++ K L D   NFSGR    +   +THD GI++K+ + W+TQRSF LKVLRDFGLGK +SIEIV NEC   L EL+  SG+ +      P  T NII++ +MN RF ++        K I + T N+     ++++F  +         I   +          +F  + I E +      +EG+D +D FLI++++L+       +F DWQLIR  VELF AGFE+TSTTL+W  + ++++ +IQ+KVH+EI  +IG +++P +N+KK L+YTQAVMDE+LR+S+V P+A+ HR F+DA + GFYIPKDS IF NLYACH D ++WE P   YPEHFL+   NG  KY PREEL+PFS GKRQC GESLAR EYF+F  S++Q+F+I F + I +  Y +   G +G +R     + +F+ R
Sbjct:    9 FILIFLYFLYWVCRKPPIPKGLKEIPMESGLPIIGAIHKIEPPMHHYLLKLGRKLGPIFRIKLGMRKIVVLNNYEMIKKALIDDANNFSGRWSPKVDAEVTHDSGIIYKDGKIWATQRSFILKVLRDFGLGKSKSIEIVQNECFNFLDELDTLSGQIVDFSELIPIYTTNIISRFIMNKRFTRDDPNVHFMEKAITKFTKNKDIFQLILLMFPCFDNSSLICQLIYLLTSEWKSFIRTQDFFADEIKEHRNALDFTSEGEDLMDRFLIKQYQLKQSTGNVESFVDWQLIRTSVELFIAGFETTSTTLNWCCLFMSKYPDIQEKVHKEISEIIGKERLPTMNDKKALNYTQAVMDEVLRLSSVVPMALIHRTFHDANINGFYIPKDSLIFPNLYACHMDPEIWEFPKTLYPEHFLSLDSNGISKYQPREELIPFSVGKRQCIGESLARSEYFIFFVSMVQRFQISFGEEISEDRYSQTIIGNEGLIRTSDIKNFLFKRR 506