Protein disulfide-isomerase
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Overview
Neoblast Clusters
Zeng et. al., 2018▻ Overview▻ Neoblast Population▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Overview
Single cell RNA-seq of pluripotent neoblasts and its early progeniesWe isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)Explore this single cell expression dataset with our NB Cluster Shiny App
Neoblast Population
Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Embryonic Expression
Davies et. al., 2017
Hover the mouse over a column in the graph to view average RPKM values per sample. Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult. back to top Anatomical Expression
PAGE et. al., 2020SMED30014062 has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGEPAGE Curations: 8
Homology
BLAST of Protein disulfide-isomerase vs. Ensembl Human
Match: P4HB (prolyl 4-hydroxylase subunit beta [Source:HGNC Symbol;Acc:HGNC:8548]) HSP 1 Score: 155.992 bits (393), Expect = 1.507e-50 Identity = 96/316 (30.38%), Postives = 165/316 (52.22%), Query Frame = 1
Query: 532 DDIKDFEIVASMHDDVEFRLLKDAELCQRFNLPTTENSIGIYQYDFGIQHTVSGKLTRNIMNDFIIKHHVPIYSEFSDFIFSKSFVG----HYHYFVPIIFKSFPIPLNEMKAEIRKIAKELDGKAIFIHFDISKKKVQRFLEHLSIPENE--GFRVVESSEHLVNFKPENPLNLNGTYMLSFIRQVMDGTAEPELMASEPRENWHLEPIKHLTRKTYDQVVMDKTKNVFVIIYAPDCPYSREMLELLDKLGEMYKDDENVLLAKLDSSVDELPRIRVRSTPMMFLYLKDTNER-IKFHGERTIENLKKFIESNGQ 1458
D K F A DD+ F + ++++ ++ L + + ++D G ++ G++T+ + DFI + +P+ EF++ K F G H F+P + L+ K A+ GK +FI D QR LE + + E R++ E + +KPE+ L + F + ++G +P LM+ E E+W +P+K L K ++ V D+ KNVFV YAP C + +++ + DKLGE YKD EN+++AK+DS+ +E+ ++V S P + + + I ++GERT++ KKF+ES GQ
Sbjct: 167 DSAKQFLQAAEAIDDIPFGITSNSDVFSKYQL-DKDGVVLFKKFDEG-RNNFEGEVTKENLLDFIKHNQLPLVIEFTEQTAPKIFGGEIKTHILLFLPKSVSDYDGKLSNFKT----AAESFKGKILFIFIDSDHTDNQRILEFFGLKKEECPAVRLITLEEEMTKYKPESE-ELTAERITEFCHRFLEGKIKPHLMSQELPEDWDKQPVKVLVGKNFEDVAFDEKKNVFVEFYAPWCGHCKQLAPIWDKLGETYKDHENIVIAKMDSTANEVEAVKVHSFPTLKFFPASADRTVIDYNGERTLDGFKKFLESGGQ 475 HSP 2 Score: 65.0846 bits (157), Expect = 1.507e-50 Identity = 41/126 (32.54%), Postives = 59/126 (46.83%), Query Frame = 2
Query: 113 EEDDHCLLLTDQNWDYAHKIYEYILVFFYKPDCDQCTLSDEIFVYAAKHAKETKHTVKFAFVDAANEKTIATLEQIETVPVMKFYRNK-TGVQYLRTQGKE--EVIQWLTDRVNYELKPISTLDDG 481
EE+DH L+L N+ A ++Y+LV FY P C C + AA K ++ A VDA E +A + P +KF+RN T T G+E +++ WL R +TL DG
Sbjct: 21 EEEDHVLVLRKSNFAEALAAHKYLLVEFYAPWCGHCKALAPEYAKAAGKLKAEGSEIRLAKVDATEESDLAQQYGVRGYPTIKFFRNGDTASPKEYTAGREADDIVNWLKKRTG---PAATTLPDG 143
BLAST of Protein disulfide-isomerase vs. Ensembl Human
Match: P4HB (prolyl 4-hydroxylase subunit beta [Source:HGNC Symbol;Acc:HGNC:8548]) HSP 1 Score: 155.606 bits (392), Expect = 3.636e-41 Identity = 96/316 (30.38%), Postives = 165/316 (52.22%), Query Frame = 1
Query: 532 DDIKDFEIVASMHDDVEFRLLKDAELCQRFNLPTTENSIGIYQYDFGIQHTVSGKLTRNIMNDFIIKHHVPIYSEFSDFIFSKSFVG----HYHYFVPIIFKSFPIPLNEMKAEIRKIAKELDGKAIFIHFDISKKKVQRFLEHLSIPENE--GFRVVESSEHLVNFKPENPLNLNGTYMLSFIRQVMDGTAEPELMASEPRENWHLEPIKHLTRKTYDQVVMDKTKNVFVIIYAPDCPYSREMLELLDKLGEMYKDDENVLLAKLDSSVDELPRIRVRSTPMMFLYLKDTNER-IKFHGERTIENLKKFIESNGQ 1458
D K F A DD+ F + ++++ ++ L + + ++D G ++ G++T+ + DFI + +P+ EF++ K F G H F+P + L+ K A+ GK +FI D QR LE + + E R++ E + +KPE+ L + F + ++G +P LM+ E E+W +P+K L K ++ V D+ KNVFV YAP C + +++ + DKLGE YKD EN+++AK+DS+ +E+ ++V S P + + + I ++GERT++ KKF+ES GQ
Sbjct: 123 DSAKQFLQAAEAIDDIPFGITSNSDVFSKYQL-DKDGVVLFKKFDEG-RNNFEGEVTKENLLDFIKHNQLPLVIEFTEQTAPKIFGGEIKTHILLFLPKSVSDYDGKLSNFKT----AAESFKGKILFIFIDSDHTDNQRILEFFGLKKEECPAVRLITLEEEMTKYKPESE-ELTAERITEFCHRFLEGKIKPHLMSQELPEDWDKQPVKVLVGKNFEDVAFDEKKNVFVEFYAPWCGHCKQLAPIWDKLGETYKDHENIVIAKMDSTANEVEAVKVHSFPTLKFFPASADRTVIDYNGERTLDGFKKFLESGGQ 431 HSP 2 Score: 56.6102 bits (135), Expect = 6.605e-8 Identity = 30/87 (34.48%), Postives = 43/87 (49.43%), Query Frame = 2
Query: 113 EEDDHCLLLTDQNWDYAHKIYEYILVFFYKPDCDQCTLSDEIFVYAAKHAKETKHTVKFAFVDAANEKTIATLEQIETVPVMKFYRN 373
EE+DH L+L N+ A ++Y+LV FY P C C + AA K ++ A VDA E +A + P +KF+RN
Sbjct: 21 EEEDHVLVLRKSNFAEALAAHKYLLVEFYAPWCGHCKALAPEYAKAAGKLKAEGSEIRLAKVDATEESDLAQQYGVRGYPTIKFFRN 107
BLAST of Protein disulfide-isomerase vs. Ensembl Human
Match: P4HB (prolyl 4-hydroxylase subunit beta [Source:HGNC Symbol;Acc:HGNC:8548]) HSP 1 Score: 137.887 bits (346), Expect = 2.135e-36 Identity = 81/259 (31.27%), Postives = 135/259 (52.12%), Query Frame = 1
Query: 691 GKLTRNIMNDFIIKHHVPIYSEFSDFIFSKSFVGHYHYFVPIIFKSFPIPLNEMKAEIRKIAKELDGKAIFIHFDISKKKVQRFLEHLSIPENE--GFRVVESSEHLVNFKPENPLNLNGTYMLSFIRQVMDGTAEPELMASEPRENWHLEPIKHLTRKTYDQVVMDKTKNVFVIIYAPDCPYSREMLELLDKLGEMYKDDENVLLAKLDSSVDELPRIRVRSTPMMFLYLKDTNER-IKFHGERTIENLKKFIESNGQ 1458
G++T+ + DFI + +P+ EF++ S + G F + A+ GK +FI D QR LE + + E R++ E + +KPE+ L + F + ++G +P LM+ E E+W +P+K L K ++ V D+ KNVFV YAP C + +++ + DKLGE YKD EN+++AK+DS+ +E+ ++V S P + + + I ++GERT++ KKF+ES GQ
Sbjct: 4 GEVTKENLLDFIKHNQLPLVIEFTEQSVS-DYDGKLSNF-------------------KTAAESFKGKILFIFIDSDHTDNQRILEFFGLKKEECPAVRLITLEEEMTKYKPESE-ELTAERITEFCHRFLEGKIKPHLMSQELPEDWDKQPVKVLVGKNFEDVAFDEKKNVFVEFYAPWCGHCKQLAPIWDKLGETYKDHENIVIAKMDSTANEVEAVKVHSFPTLKFFPASADRTVIDYNGERTLDGFKKFLESGGQ 241
BLAST of Protein disulfide-isomerase vs. Ensembl Human
Match: PDIA2 (protein disulfide isomerase family A member 2 [Source:HGNC Symbol;Acc:HGNC:14180]) HSP 1 Score: 110.923 bits (276), Expect = 1.749e-31 Identity = 81/324 (25.00%), Postives = 153/324 (47.22%), Query Frame = 1
Query: 532 DDIKDFEIVASMHDDVEFRLLKDAELCQRFNLPTTENSIGIYQ------YDFGIQHTVS---GKLTRNIMNDFIIKHHVPIYSEF----SDFIFSKSFVGHYHYFVPIIFKSFPIPLNEMKAEIRKIAKELDGKAIFIHFDISKKKVQRFLEHLSIPENEG--FRVVESSEHLVNFKPENPLNLNGTYMLSFIRQVMDGTAEPELMASEPRENWHLEPIKHLTRKTYDQVVMDKTKNVFVIIYAPDCPYSREMLELLDKLGEMYKDDENVLLAKLDSSVDELPRIRVRSTPMMFLYLKDTNER-IKFHGERTIENLKKFIESNG 1455
+D+ F +A D+ F L L Q+F L T++++ +++ DF + + G L+R F++ H + + +EF S IF+ + H FV + E+ A + A G+ +F+ D++ + L++ + R+V + E + P + + + +F V++G +P L++ E +W P+K L K ++QV D+TKNVFV YAP C + +EM + L E Y+D E++++A+LD++ +EL V P + + + I++ R +E KF+++ G
Sbjct: 185 EDVATFLALAQDALDMTFGLTDRPRLFQQFGL--TKDTVVLFKKFDEGRADFPVDEELGLDLGDLSR-----FLVTHSMRLVTEFNSQTSAKIFAARILNHLLLFVNQTLAAH----RELLAGFGEAAPRFRGQVLFVVVDVAADN-EHVLQYFGLKAEAAPTLRLV-NLETTKKYAPVDGGPVTAASITAFCHAVLNGQVKPYLLSQEIPPDWDQRPVKTLVGKNFEQVAFDETKNVFVKFYAPWCTHCKEMAPAWEALAEKYQDHEDIIIAELDATANELDAFAVHGFPTLKYFPAGPGRKVIEYKSTRDLETFSKFLDNGG 495 HSP 2 Score: 46.2098 bits (108), Expect = 1.749e-31 Identity = 37/137 (27.01%), Postives = 57/137 (41.61%), Query Frame = 2
Query: 122 DHCLLLTDQNWDYAHKIYEYILVFFYKPDCDQC-TLSDEIFVYAAKHAKETKHTVKFAFVDAANEKTIATLEQIETVPVMKFYRNKTGV---QYLRTQGKEEVIQWLTDRVNYELKPISTLDDGKNTLLNNLLVVFG 520
D L+L+ A + + +LV FY P C C L+ E AA A E+ V A VD ++ +A + P +KF+RN +Y + E + +WL RV + + + LVV G
Sbjct: 42 DGILVLSRHTLGLALREHPALLVEFYAPWCGHCQALAPEYSKAAAVLAAES-MVVTLAKVDGPAQRELAEEFGVTEYPTLKFFRNGNRTHPEEYTGPRDAEGIAEWLRRRVGPSAMRLEDEAAAQALIGGRDLVVIG 177
BLAST of Protein disulfide-isomerase vs. Ensembl Human
Match: PDIA2 (protein disulfide isomerase family A member 2 [Source:HGNC Symbol;Acc:HGNC:14180]) HSP 1 Score: 110.538 bits (275), Expect = 1.779e-31 Identity = 81/324 (25.00%), Postives = 153/324 (47.22%), Query Frame = 1
Query: 532 DDIKDFEIVASMHDDVEFRLLKDAELCQRFNLPTTENSIGIYQ------YDFGIQHTVS---GKLTRNIMNDFIIKHHVPIYSEF----SDFIFSKSFVGHYHYFVPIIFKSFPIPLNEMKAEIRKIAKELDGKAIFIHFDISKKKVQRFLEHLSIPENEG--FRVVESSEHLVNFKPENPLNLNGTYMLSFIRQVMDGTAEPELMASEPRENWHLEPIKHLTRKTYDQVVMDKTKNVFVIIYAPDCPYSREMLELLDKLGEMYKDDENVLLAKLDSSVDELPRIRVRSTPMMFLYLKDTNER-IKFHGERTIENLKKFIESNG 1455
+D+ F +A D+ F L L Q+F L T++++ +++ DF + + G L+R F++ H + + +EF S IF+ + H FV + E+ A + A G+ +F+ D++ + L++ + R+V + E + P + + + +F V++G +P L++ E +W P+K L K ++QV D+TKNVFV YAP C + +EM + L E Y+D E++++A+LD++ +EL V P + + + I++ R +E KF+++ G
Sbjct: 182 EDVATFLALAQDALDMTFGLTDRPRLFQQFGL--TKDTVVLFKKFDEGRADFPVDEELGLDLGDLSR-----FLVTHSMRLVTEFNSQTSAKIFAARILNHLLLFVNQTLAAH----RELLAGFGEAAPRFRGQVLFVVVDVAADN-EHVLQYFGLKAEAAPTLRLV-NLETTKKYAPVDGGPVTAASITAFCHAVLNGQVKPYLLSQEIPPDWDQRPVKTLVGKNFEQVAFDETKNVFVKFYAPWCTHCKEMAPAWEALAEKYQDHEDIIIAELDATANELDAFAVHGFPTLKYFPAGPGRKVIEYKSTRDLETFSKFLDNGG 492 HSP 2 Score: 46.2098 bits (108), Expect = 1.779e-31 Identity = 37/137 (27.01%), Postives = 57/137 (41.61%), Query Frame = 2
Query: 122 DHCLLLTDQNWDYAHKIYEYILVFFYKPDCDQC-TLSDEIFVYAAKHAKETKHTVKFAFVDAANEKTIATLEQIETVPVMKFYRNKTGV---QYLRTQGKEEVIQWLTDRVNYELKPISTLDDGKNTLLNNLLVVFG 520
D L+L+ A + + +LV FY P C C L+ E AA A E+ V A VD ++ +A + P +KF+RN +Y + E + +WL RV + + + LVV G
Sbjct: 42 DGILVLSRHTLGLALREHPALLVEFYAPWCGHCQALAPEYSKAAAVLAAES-MVVTLAKVDGPAQRELAEEFGVTEYPTLKFFRNGNRTHPEEYTGPRDAEGIAEWLRRRVGPSAMRLEDEAAAQALIGGRDLVVIG 177
BLAST of Protein disulfide-isomerase vs. Ensembl Celegans
Match: pdi-2 (Protein disulfide-isomerase 2 [Source:UniProtKB/Swiss-Prot;Acc:Q17770]) HSP 1 Score: 151.754 bits (382), Expect = 7.630e-51 Identity = 92/317 (29.02%), Postives = 168/317 (53.00%), Query Frame = 1
Query: 532 DDIKDFEIVASMHDDVEFRLLKDAELCQRFNLPTTENSIGIYQYDFGIQHTVSGKLTRNIMNDFIIKHHVPIYSEF----SDFIFSKSFVGHYHYFVPIIFKSFPIPLNEMKAEIRKIAKELDGKAIFIHFDISKKKVQRFLEHLSIPENE--GFRVVESSEHLVNFKPENPLNLNGTYMLSFIRQVMDGTAEPELMASEPRENWHLEPIKHLTRKTYDQVVMDKTKNVFVIIYAPDCPYSREMLELLDKLGEMYKDDENVLLAKLDSSVDELPRIRVRSTPMMFLYLKDTNERIKFHGERTIENLKKFIESNGQDG 1464
DD K F VA+ DDV F + + + L E + ++D G + KLT++ + +I + + + SEF + IF H FV F +++ E + AK+ GK +F++ + ++ R +E + ++E R++ E + FKP+ + + F + +DG+ +P LM+ + E+W P+K L K ++QV D TKNV V YAP C + +++ DKLGE + DDE++++AK+DS+++E+ ++++S P + + +N+ + + G+RTIE KF+E+NG++G
Sbjct: 163 DDAKTFLEVAAGIDDVPFGISTEDAVKSEIELKG-EGIVLFKKFDDG-RVAFDEKLTQDGLKTWIQANRLALVSEFTQETASVIFGGEIKSHNLLFVSKESSEFA----KLEQEFKNAAKQFKGKVLFVYINTDVEENARIMEFFGLKKDELPAIRLISLEEDMTKFKPDFE-EITTENISKFTQNYLDGSVKPHLMSEDIPEDWDKNPVKILVGKNFEQVARDNTKNVLVEFYAPWCGHCKQLAPTWDKLGEKFADDESIVIAKMDSTLNEVEDVKIQSFPTIKFFPAGSNKVVDYTGDRTIEGFTKFLETNGKEG 472 HSP 2 Score: 68.5514 bits (166), Expect = 7.630e-51 Identity = 41/151 (27.15%), Postives = 69/151 (45.70%), Query Frame = 2
Query: 68 LSLSFYCNGDEIPIIEEDDHCLLLTDQNWDYAHKIYEYILVFFYKPDCDQCTLSDEIFVYAAKHAKETKHTVKFAFVDAANEKTIATLEQIETVPVMKFYRNKTGVQYLRTQGKEEVIQWLTDRVNYELKPISTLDDGKNTLLNNLLVVFG 520
+ L F G +IEE+++ ++LT N+D E+ILV FY P C C + AA KE +K +DA +++ ++ P +K +RN +Y + + +I WL + KP++ D K + +VV G
Sbjct: 5 VGLFFLVLGASAAVIEEEENVIVLTKDNFDEVINGNEFILVEFYAPWCGHCKSLAPEYAKAATQLKEEGSDIKLGKLDATVHGEVSSKFEVRGYPTLKLFRNGKPQEYNGGRDHDSIIAWLKKKTGPVAKPLADADAVKELQESADVVVIG 155
BLAST of Protein disulfide-isomerase vs. Ensembl Celegans
Match: pdi-2 (Protein disulfide-isomerase 2 [Source:UniProtKB/Swiss-Prot;Acc:Q17770]) HSP 1 Score: 151.754 bits (382), Expect = 7.630e-51 Identity = 92/317 (29.02%), Postives = 168/317 (53.00%), Query Frame = 1
Query: 532 DDIKDFEIVASMHDDVEFRLLKDAELCQRFNLPTTENSIGIYQYDFGIQHTVSGKLTRNIMNDFIIKHHVPIYSEF----SDFIFSKSFVGHYHYFVPIIFKSFPIPLNEMKAEIRKIAKELDGKAIFIHFDISKKKVQRFLEHLSIPENE--GFRVVESSEHLVNFKPENPLNLNGTYMLSFIRQVMDGTAEPELMASEPRENWHLEPIKHLTRKTYDQVVMDKTKNVFVIIYAPDCPYSREMLELLDKLGEMYKDDENVLLAKLDSSVDELPRIRVRSTPMMFLYLKDTNERIKFHGERTIENLKKFIESNGQDG 1464
DD K F VA+ DDV F + + + L E + ++D G + KLT++ + +I + + + SEF + IF H FV F +++ E + AK+ GK +F++ + ++ R +E + ++E R++ E + FKP+ + + F + +DG+ +P LM+ + E+W P+K L K ++QV D TKNV V YAP C + +++ DKLGE + DDE++++AK+DS+++E+ ++++S P + + +N+ + + G+RTIE KF+E+NG++G
Sbjct: 163 DDAKTFLEVAAGIDDVPFGISTEDAVKSEIELKG-EGIVLFKKFDDG-RVAFDEKLTQDGLKTWIQANRLALVSEFTQETASVIFGGEIKSHNLLFVSKESSEFA----KLEQEFKNAAKQFKGKVLFVYINTDVEENARIMEFFGLKKDELPAIRLISLEEDMTKFKPDFE-EITTENISKFTQNYLDGSVKPHLMSEDIPEDWDKNPVKILVGKNFEQVARDNTKNVLVEFYAPWCGHCKQLAPTWDKLGEKFADDESIVIAKMDSTLNEVEDVKIQSFPTIKFFPAGSNKVVDYTGDRTIEGFTKFLETNGKEG 472 HSP 2 Score: 68.5514 bits (166), Expect = 7.630e-51 Identity = 41/151 (27.15%), Postives = 69/151 (45.70%), Query Frame = 2
Query: 68 LSLSFYCNGDEIPIIEEDDHCLLLTDQNWDYAHKIYEYILVFFYKPDCDQCTLSDEIFVYAAKHAKETKHTVKFAFVDAANEKTIATLEQIETVPVMKFYRNKTGVQYLRTQGKEEVIQWLTDRVNYELKPISTLDDGKNTLLNNLLVVFG 520
+ L F G +IEE+++ ++LT N+D E+ILV FY P C C + AA KE +K +DA +++ ++ P +K +RN +Y + + +I WL + KP++ D K + +VV G
Sbjct: 5 VGLFFLVLGASAAVIEEEENVIVLTKDNFDEVINGNEFILVEFYAPWCGHCKSLAPEYAKAATQLKEEGSDIKLGKLDATVHGEVSSKFEVRGYPTLKLFRNGKPQEYNGGRDHDSIIAWLKKKTGPVAKPLADADAVKELQESADVVVIG 155
BLAST of Protein disulfide-isomerase vs. Ensembl Celegans
Match: pdi-2 (Protein disulfide-isomerase 2 [Source:UniProtKB/Swiss-Prot;Acc:Q17770]) HSP 1 Score: 141.354 bits (355), Expect = 1.134e-36 Identity = 76/261 (29.12%), Postives = 142/261 (54.41%), Query Frame = 1
Query: 700 TRNIMNDFIIKHHVPIYSEF----SDFIFSKSFVGHYHYFVPIIFKSFPIPLNEMKAEIRKIAKELDGKAIFIHFDISKKKVQRFLEHLSIPENE--GFRVVESSEHLVNFKPENPLNLNGTYMLSFIRQVMDGTAEPELMASEPRENWHLEPIKHLTRKTYDQVVMDKTKNVFVIIYAPDCPYSREMLELLDKLGEMYKDDENVLLAKLDSSVDELPRIRVRSTPMMFLYLKDTNERIKFHGERTIENLKKFIESNGQDG 1464
T + +I + + + SEF + IF H FV F +++ E + AK+ GK +F++ + ++ R +E + ++E R++ E + FKP+ + + F + +DG+ +P LM+ + E+W P+K L K ++QV D TKNV V YAP C + +++ DKLGE + DDE++++AK+DS+++E+ ++++S P + + +N+ + + G+RTIE KF+E+NG++G
Sbjct: 161 TSDDAKTWIQANRLALVSEFTQETASVIFGGEIKSHNLLFVSKESSEFA----KLEQEFKNAAKQFKGKVLFVYINTDVEENARIMEFFGLKKDELPAIRLISLEEDMTKFKPDFE-EITTENISKFTQNYLDGSVKPHLMSEDIPEDWDKNPVKILVGKNFEQVARDNTKNVLVEFYAPWCGHCKQLAPTWDKLGEKFADDESIVIAKMDSTLNEVEDVKIQSFPTIKFFPAGSNKVVDYTGDRTIEGFTKFLETNGKEG 416 HSP 2 Score: 71.2478 bits (173), Expect = 4.937e-13 Identity = 51/192 (26.56%), Postives = 86/192 (44.79%), Query Frame = 2
Query: 68 LSLSFYCNGDEIPIIEEDDHCLLLTDQNWDYAHKIYEYILVFFYKPDCDQCTLSDEIFVYAAKHAKETKHTVKFAFVDAANEKTIATLEQIETVPVMKFYRNKTGVQYLRTQGKEEVIQWLTDRVNYELKPISTLDDGKNTLLNNLLVVFGCIL*MILRTLKSW-PVCMMMLNSDC*KTQNSASVLTFQQLK 640
+ L F G +IEE+++ ++LT N+D E+ILV FY P C C + AA KE +K +DA +++ ++ P +K +RN +Y + + +I WL + KP++ D K + +VV G K+W + L S+ TQ +ASV+ ++K
Sbjct: 5 VGLFFLVLGASAAVIEEEENVIVLTKDNFDEVINGNEFILVEFYAPWCGHCKSLAPEYAKAATQLKEEGSDIKLGKLDATVHGEVSSKFEVRGYPTLKLFRNGKPQEYNGGRDHDSIIAWLKKKTGPVAKPLADADAVKELQESADVVVIGYFKDTTSDDAKTWIQANRLALVSEF--TQETASVIFGGEIK 194
BLAST of Protein disulfide-isomerase vs. Ensembl Celegans
Match: pdi-2 (Protein disulfide-isomerase 2 [Source:UniProtKB/Swiss-Prot;Acc:Q17770]) HSP 1 Score: 141.354 bits (355), Expect = 1.134e-36 Identity = 76/261 (29.12%), Postives = 142/261 (54.41%), Query Frame = 1
Query: 700 TRNIMNDFIIKHHVPIYSEF----SDFIFSKSFVGHYHYFVPIIFKSFPIPLNEMKAEIRKIAKELDGKAIFIHFDISKKKVQRFLEHLSIPENE--GFRVVESSEHLVNFKPENPLNLNGTYMLSFIRQVMDGTAEPELMASEPRENWHLEPIKHLTRKTYDQVVMDKTKNVFVIIYAPDCPYSREMLELLDKLGEMYKDDENVLLAKLDSSVDELPRIRVRSTPMMFLYLKDTNERIKFHGERTIENLKKFIESNGQDG 1464
T + +I + + + SEF + IF H FV F +++ E + AK+ GK +F++ + ++ R +E + ++E R++ E + FKP+ + + F + +DG+ +P LM+ + E+W P+K L K ++QV D TKNV V YAP C + +++ DKLGE + DDE++++AK+DS+++E+ ++++S P + + +N+ + + G+RTIE KF+E+NG++G
Sbjct: 161 TSDDAKTWIQANRLALVSEFTQETASVIFGGEIKSHNLLFVSKESSEFA----KLEQEFKNAAKQFKGKVLFVYINTDVEENARIMEFFGLKKDELPAIRLISLEEDMTKFKPDFE-EITTENISKFTQNYLDGSVKPHLMSEDIPEDWDKNPVKILVGKNFEQVARDNTKNVLVEFYAPWCGHCKQLAPTWDKLGEKFADDESIVIAKMDSTLNEVEDVKIQSFPTIKFFPAGSNKVVDYTGDRTIEGFTKFLETNGKEG 416 HSP 2 Score: 71.2478 bits (173), Expect = 4.937e-13 Identity = 51/192 (26.56%), Postives = 86/192 (44.79%), Query Frame = 2
Query: 68 LSLSFYCNGDEIPIIEEDDHCLLLTDQNWDYAHKIYEYILVFFYKPDCDQCTLSDEIFVYAAKHAKETKHTVKFAFVDAANEKTIATLEQIETVPVMKFYRNKTGVQYLRTQGKEEVIQWLTDRVNYELKPISTLDDGKNTLLNNLLVVFGCIL*MILRTLKSW-PVCMMMLNSDC*KTQNSASVLTFQQLK 640
+ L F G +IEE+++ ++LT N+D E+ILV FY P C C + AA KE +K +DA +++ ++ P +K +RN +Y + + +I WL + KP++ D K + +VV G K+W + L S+ TQ +ASV+ ++K
Sbjct: 5 VGLFFLVLGASAAVIEEEENVIVLTKDNFDEVINGNEFILVEFYAPWCGHCKSLAPEYAKAATQLKEEGSDIKLGKLDATVHGEVSSKFEVRGYPTLKLFRNGKPQEYNGGRDHDSIIAWLKKKTGPVAKPLADADAVKELQESADVVVIGYFKDTTSDDAKTWIQANRLALVSEF--TQETASVIFGGEIK 194
BLAST of Protein disulfide-isomerase vs. Ensembl Celegans
Match: pdi-1 (Protein disulfide-isomerase 1 [Source:UniProtKB/Swiss-Prot;Acc:Q17967]) HSP 1 Score: 119.013 bits (297), Expect = 6.627e-36 Identity = 74/296 (25.00%), Postives = 146/296 (49.32%), Query Frame = 1
Query: 637 ENSIGIYQYDFGIQHTVSGKLTRNIMNDFIIKHHVPIY-----SEFSDFIFSKSFVGHYHYFVPIIFKSFPIPLNEMKAEIRKIAKELDGKAIFIHFDISKKKVQRFLEHLSI-----PENEGFRVVESSEHLVNFKPENPLNLNGTYMLSFIRQVMDGTAEPELMASEPRENWHLEPIKHLTRKTYDQVVMDKTKNVFVIIYAPDCPYSREMLELLDKLGEMYKDDENVLLAKLDSSVDELPRIRVRSTPMMFLYLKDTNERIKFHGERTIENLKKFIESNGQDGNEQQFLEIDH 1494
E+ + + + D G S I N +K + Y +EF+ + G F +I + +E A+ ++AK+ K +F+ D+ ++ R LE L + P N R+V ++ + FKP+ G +F ++G + +L A + E+W+ P+K L ++++ +D+TK VFV YAP C + ++++ + D+L E Y+ + NV++AKLD++++EL ++V S P + L+ ++ + + G+R +E ++F+ +E + DH
Sbjct: 196 EDGVALIRTD-GDDSETSTIAEAEITNTIALKQWLHAYKLSAVTEFTHESAQEIVGGDLKKFHFLIIRKSDSSFDETIAKFTEVAKKFRAKIVFVLLDVDVEENARILEFLGVDAKNTPAN---RIVSLADQVEKFKPQE-----GEDFEAFTNSYLEGKSAQDLKAQDLPEDWNALPVKVLVASNFNEIALDETKTVFVKFYAPWCGHCKQLVPVWDELAEKYESNPNVVIAKLDATLNELADVKVNSFPTLKLWPAGSSTPVDYDGDRNLEKFEEFVNKYAGSASESETASQDH 482 HSP 2 Score: 51.6026 bits (122), Expect = 6.627e-36 Identity = 28/138 (20.29%), Postives = 65/138 (47.10%), Query Frame = 2
Query: 107 IIEEDDHCLLLTDQNWDYAHKIYEYILVFFYKPDCDQCTLSDEIFVYAAKHAKETKHTVKFAFVDAANEKTIATLEQIETVPVMKFYRNKTGVQYLRTQGKEEVIQWLTDRVNYELKPISTLDDGKNTLLNNLLVVFG 520
++ + ++ L+LT+ N++ E++LV FY P C C + AA KE +K A VDA + +A+ ++ P + ++++ +Y + +++ W+ + + + +++ + +VV G
Sbjct: 18 VVADSENVLVLTESNFEETINGNEFVLVKFYAPWCVHCKSLAPKYDEAADLLKEEGSDIKLAKVDATENQALASKFEVRGYPTILYFKSGKPTKYTGGRATAQIVDWVKKKSGPTVTTVESVEQLEELKGKTRVVVLG 155
BLAST of Protein disulfide-isomerase vs. Ensembl Fly
Match: Pdi (gene:FBgn0286818 transcript:FBtr0346644) HSP 1 Score: 124.02 bits (310), Expect = 2.007e-41 Identity = 81/318 (25.47%), Postives = 165/318 (51.89%), Query Frame = 1
Query: 532 DDIKDFEIVASMHDDVEFRLLKDAELCQRFNLPTTENSIGIYQYDFGIQHTVSGKLTRNIMNDFIIKHHVPIYSEF----SDFIFSKSFVGHYHYFVPII---FKSFPIPLNEMKAEIRKIAKELDGKAIFIHFDISKKKVQRFLEHLSIPENE--GFRVVESSEHLVNFKPENPLNLNGTYMLSFIRQVMDGTAEPELMASEPRENWHLEPIKHLTRKTYDQVVMDKTKNVFVIIYAPDCPYSREMLELLDKLGEMYKDDENVLLAKLDSSVDELPRIRVRSTPMMFLYLKDTNERIKFHGERTIENLKKFIESNGQ 1458
++ K F VA+ D F + +A++ ++ +N + +++ + G+L + F +P+ +F + IF S H +FV + + PL E IAK+ +F+ ++ R E + + E R+++ E + +KPE+ +L+ + +F+++ +DG + L++ E E+W P+K L ++ V +DK+K+V V YAP C + +++ + D+L E YKD+E++++AK+DS+ +EL I++ S P + + K+ N+ I F+ +RT+++ KF+++NG+
Sbjct: 167 EEAKTFTKVANALDSFVFGVSSNADVIAKYE--AKDNGVVLFKPFDDKKSVFEGELNEENLKKFAQVQSLPLIVDFNHESASKIFGGSIKSHLLFFVSREGGHIEKYVDPLKE-------IAKKYRDDILFVTISSDEEDHTRIFEFFGMNKEEVPTIRLIKLEEDMAKYKPESD-DLSAETIEAFLKKFLDGKLKQHLLSQELPEDWDKNPVKVLVSSNFESVALDKSKSVLVEFYAPWCGHCKQLAPIYDQLAEKYKDNEDIVIAKMDSTANELESIKISSFPTIKYFRKEDNKVIDFNLDRTLDDFVKFLDANGE 474 HSP 2 Score: 65.4698 bits (158), Expect = 2.007e-41 Identity = 42/155 (27.10%), Postives = 74/155 (47.74%), Query Frame = 2
Query: 56 ALFSLSLSFYCNGDEIPIIEEDDHCLLLTDQNWDYAHKIYEYILVFFYKPDCDQCTLSDEIFVYAAKHAKETKHTVKFAFVDAANEKTIATLEQIETVPVMKFYRNKTGVQYLRTQGKEEVIQWLTDRVNYELKPISTLDDGKNTLLNNLLVVFG 520
ALF L+ S+ E + E+ L+ T N+ E++LV FY P C C + AA+ E + +K A VDA E +A + P +KF+R+ + V+Y + ++I W+T + K ++++ D + L +N + + G
Sbjct: 7 ALF-LAASYVAASAEAEVKVEE-GVLVATVDNFKQLIADNEFVLVEFYAPWCGHCKALAPEYAKAAQQLAEKESPIKLAKVDATVEGELAEQYAVRGYPTLKFFRSGSPVEYSGGRQAADIIAWVTKKTGPPAKDLTSVADAEQFLKDNEIAIIG 159
BLAST of Protein disulfide-isomerase vs. Ensembl Fly
Match: Pdi (gene:FBgn0286818 transcript:FBtr0075648) HSP 1 Score: 124.02 bits (310), Expect = 2.007e-41 Identity = 81/318 (25.47%), Postives = 165/318 (51.89%), Query Frame = 1
Query: 532 DDIKDFEIVASMHDDVEFRLLKDAELCQRFNLPTTENSIGIYQYDFGIQHTVSGKLTRNIMNDFIIKHHVPIYSEF----SDFIFSKSFVGHYHYFVPII---FKSFPIPLNEMKAEIRKIAKELDGKAIFIHFDISKKKVQRFLEHLSIPENE--GFRVVESSEHLVNFKPENPLNLNGTYMLSFIRQVMDGTAEPELMASEPRENWHLEPIKHLTRKTYDQVVMDKTKNVFVIIYAPDCPYSREMLELLDKLGEMYKDDENVLLAKLDSSVDELPRIRVRSTPMMFLYLKDTNERIKFHGERTIENLKKFIESNGQ 1458
++ K F VA+ D F + +A++ ++ +N + +++ + G+L + F +P+ +F + IF S H +FV + + PL E IAK+ +F+ ++ R E + + E R+++ E + +KPE+ +L+ + +F+++ +DG + L++ E E+W P+K L ++ V +DK+K+V V YAP C + +++ + D+L E YKD+E++++AK+DS+ +EL I++ S P + + K+ N+ I F+ +RT+++ KF+++NG+
Sbjct: 167 EEAKTFTKVANALDSFVFGVSSNADVIAKYE--AKDNGVVLFKPFDDKKSVFEGELNEENLKKFAQVQSLPLIVDFNHESASKIFGGSIKSHLLFFVSREGGHIEKYVDPLKE-------IAKKYRDDILFVTISSDEEDHTRIFEFFGMNKEEVPTIRLIKLEEDMAKYKPESD-DLSAETIEAFLKKFLDGKLKQHLLSQELPEDWDKNPVKVLVSSNFESVALDKSKSVLVEFYAPWCGHCKQLAPIYDQLAEKYKDNEDIVIAKMDSTANELESIKISSFPTIKYFRKEDNKVIDFNLDRTLDDFVKFLDANGE 474 HSP 2 Score: 65.4698 bits (158), Expect = 2.007e-41 Identity = 42/155 (27.10%), Postives = 74/155 (47.74%), Query Frame = 2
Query: 56 ALFSLSLSFYCNGDEIPIIEEDDHCLLLTDQNWDYAHKIYEYILVFFYKPDCDQCTLSDEIFVYAAKHAKETKHTVKFAFVDAANEKTIATLEQIETVPVMKFYRNKTGVQYLRTQGKEEVIQWLTDRVNYELKPISTLDDGKNTLLNNLLVVFG 520
ALF L+ S+ E + E+ L+ T N+ E++LV FY P C C + AA+ E + +K A VDA E +A + P +KF+R+ + V+Y + ++I W+T + K ++++ D + L +N + + G
Sbjct: 7 ALF-LAASYVAASAEAEVKVEE-GVLVATVDNFKQLIADNEFVLVEFYAPWCGHCKALAPEYAKAAQQLAEKESPIKLAKVDATVEGELAEQYAVRGYPTLKFFRSGSPVEYSGGRQAADIIAWVTKKTGPPAKDLTSVADAEQFLKDNEIAIIG 159
BLAST of Protein disulfide-isomerase vs. Ensembl Fly
Match: ERp60 (gene:FBgn0033663 transcript:FBtr0088058) HSP 1 Score: 63.1586 bits (152), Expect = 2.688e-10 Identity = 35/133 (26.32%), Postives = 74/133 (55.64%), Query Frame = 1
Query: 1051 MLSFIRQVMDGTAEPELMASEPRENWHLEPIKHLTRKTYDQVVMDKTKNVFVIIYAPDCPYSREMLELLDKLGEMYKDDENVLLAKLDSSVDEL-PRIRVRSTPMMFLYLKDT-NERIKFHGERTIENLKKFI 1443
+ F+ +++ EP + SEP + P+K K +D +V++ K+ + YAP C + +++ + ++L E + DE+V + K+D++ +++ P VR P +F KD N+ + ++G R +++ K+I
Sbjct: 337 LQDFVEKLLANELEP-YIKSEPIPESNDAPVKVAVAKNFDDLVINNGKDTLIEFYAPWCGHCKKLSPIYEELAEKLQ-DEDVAIVKMDATANDVPPEFNVRGFPTLFWLPKDAKNKPVSYNGGREVDDFLKYI 467
BLAST of Protein disulfide-isomerase vs. Ensembl Zebrafish
Match: p4hb (prolyl 4-hydroxylase, beta polypeptide [Source:ZFIN;Acc:ZDB-GENE-080610-1]) HSP 1 Score: 157.532 bits (397), Expect = 7.211e-49 Identity = 96/320 (30.00%), Postives = 174/320 (54.37%), Query Frame = 1
Query: 532 DDIKDFEIVASMHDDVEFRLLKDAELCQRFNLPTTENSIGIYQ-YDFGIQHTVSGKLTRNIMNDFIIKHHVPIYSEFSDFIFSKSFVG----HYHYFVPIIFKSFPIPLNEMKAEIRKIAKELDGKAIFIHFDISKKKVQRFLEHLSIPENEG--FRVVESSEHLVNFKPENPLNLNGTYMLSFIRQVMDGTAEPELMASEPRENWHLEPIKHLTRKTYDQVVMDKTKNVFVIIYAPDCPYSREMLELLDKLGEMYKDDENVLLAKLDSSVDELPRIRVRSTPMM-FLYLKDTNERIKFHGERTIENLKKFIESNGQDGN 1467
+D K F A DD+ F + D + +F + ++S+ +++ +D G ++T G++++ + +FI + +P+ EF++ K F G H FVP K F +++ K K A+ GK +FI D QR LE + + E R++ E + +KPE+ + ++SF ++GT +P LM+ + E+W P+K L K +++V + NVFV YAP C + +++ + D+LGE +KD+ N+++AK+DS+ +E+ ++V S P + F D + I ++GERT++ KF+ES G++G
Sbjct: 165 EDSKAFIKTAEAVDDIPFGITSDDSVFAKFEV--AKDSVVLFKKFDEG-RNTFDGEVSKESLLNFIKANQLPLVIEFTEQTAPKIFGGDIKSHILMFVPKAAKDFQDKMDQFK----KAAEGFKGKILFIFIDSDVDDNQRILEFFGLKKEECPVIRLITLEEEMTKYKPESS-EITAENIISFCTSFVEGTLKPHLMSQDIPEDWDKNPVKVLVGKNFEEVAFNPANNVFVEFYAPWCGHCKQLAPIWDQLGEKFKDNANIVVAKMDSTANEIEAVKVHSFPTLKFFPAGDERKVIDYNGERTLDGFTKFLESGGKEGG 476 HSP 2 Score: 57.3806 bits (137), Expect = 7.211e-49 Identity = 43/166 (25.90%), Postives = 73/166 (43.98%), Query Frame = 2
Query: 32 MSKSLITFALFSLSLSFYCNGDEIPIIEEDDHCLLLTDQNWDYAHKIYEYILVFFYKPDCDQCTLSDEIFVYAAKHAKETKHTVKFAFVDAANEKTIATLEQIETVPVMKFYRN---KTGVQYLRTQGKEEVIQWLTDRVNYELKPISTLDDGKNTLLNNLLVVFG 520
M K LI AL ++S + I EE+D L+L N++ A K + +LV FY P C C + AA K ++ A VDA E +A + P +KF++ +Y + E+++ WL R ++ + ++ + +N + V G
Sbjct: 1 MLKFLIVCALAAMSAA--------EIAEEED-VLVLKKSNFEEALKAHPNVLVEFYAPWCGHCKALAPEYSKAAGMLKAEGSDIRLAKVDATEESELAQEFGVRGYPTIKFFKGGEKGNPKEYSAGRQAEDIVSWLKKRTGPAATTLNDVMQAESIIADNEVAVIG 157
BLAST of Protein disulfide-isomerase vs. Ensembl Zebrafish
Match: p4hb (prolyl 4-hydroxylase, beta polypeptide [Source:ZFIN;Acc:ZDB-GENE-080610-1]) HSP 1 Score: 157.532 bits (397), Expect = 7.211e-49 Identity = 96/320 (30.00%), Postives = 174/320 (54.37%), Query Frame = 1
Query: 532 DDIKDFEIVASMHDDVEFRLLKDAELCQRFNLPTTENSIGIYQ-YDFGIQHTVSGKLTRNIMNDFIIKHHVPIYSEFSDFIFSKSFVG----HYHYFVPIIFKSFPIPLNEMKAEIRKIAKELDGKAIFIHFDISKKKVQRFLEHLSIPENEG--FRVVESSEHLVNFKPENPLNLNGTYMLSFIRQVMDGTAEPELMASEPRENWHLEPIKHLTRKTYDQVVMDKTKNVFVIIYAPDCPYSREMLELLDKLGEMYKDDENVLLAKLDSSVDELPRIRVRSTPMM-FLYLKDTNERIKFHGERTIENLKKFIESNGQDGN 1467
+D K F A DD+ F + D + +F + ++S+ +++ +D G ++T G++++ + +FI + +P+ EF++ K F G H FVP K F +++ K K A+ GK +FI D QR LE + + E R++ E + +KPE+ + ++SF ++GT +P LM+ + E+W P+K L K +++V + NVFV YAP C + +++ + D+LGE +KD+ N+++AK+DS+ +E+ ++V S P + F D + I ++GERT++ KF+ES G++G
Sbjct: 165 EDSKAFIKTAEAVDDIPFGITSDDSVFAKFEV--AKDSVVLFKKFDEG-RNTFDGEVSKESLLNFIKANQLPLVIEFTEQTAPKIFGGDIKSHILMFVPKAAKDFQDKMDQFK----KAAEGFKGKILFIFIDSDVDDNQRILEFFGLKKEECPVIRLITLEEEMTKYKPESS-EITAENIISFCTSFVEGTLKPHLMSQDIPEDWDKNPVKVLVGKNFEEVAFNPANNVFVEFYAPWCGHCKQLAPIWDQLGEKFKDNANIVVAKMDSTANEIEAVKVHSFPTLKFFPAGDERKVIDYNGERTLDGFTKFLESGGKEGG 476 HSP 2 Score: 57.3806 bits (137), Expect = 7.211e-49 Identity = 43/166 (25.90%), Postives = 73/166 (43.98%), Query Frame = 2
Query: 32 MSKSLITFALFSLSLSFYCNGDEIPIIEEDDHCLLLTDQNWDYAHKIYEYILVFFYKPDCDQCTLSDEIFVYAAKHAKETKHTVKFAFVDAANEKTIATLEQIETVPVMKFYRN---KTGVQYLRTQGKEEVIQWLTDRVNYELKPISTLDDGKNTLLNNLLVVFG 520
M K LI AL ++S + I EE+D L+L N++ A K + +LV FY P C C + AA K ++ A VDA E +A + P +KF++ +Y + E+++ WL R ++ + ++ + +N + V G
Sbjct: 1 MLKFLIVCALAAMSAA--------EIAEEED-VLVLKKSNFEEALKAHPNVLVEFYAPWCGHCKALAPEYSKAAGMLKAEGSDIRLAKVDATEESELAQEFGVRGYPTIKFFKGGEKGNPKEYSAGRQAEDIVSWLKKRTGPAATTLNDVMQAESIIADNEVAVIG 157
BLAST of Protein disulfide-isomerase vs. Ensembl Zebrafish
Match: pdia2 (protein disulfide isomerase family A, member 2 [Source:ZFIN;Acc:ZDB-GENE-040426-705]) HSP 1 Score: 130.954 bits (328), Expect = 4.218e-32 Identity = 90/315 (28.57%), Postives = 167/315 (53.02%), Query Frame = 1
Query: 541 KDFEIVASMHDDVEFRLLKDAELCQRFNLPTTENSIGIYQYD---FGIQHTVSGKLTRNIMNDFI----IKHHVPIYSEFSDFIFSKSFVGHYHYFVPIIFKSFPIPLNEMKAEIRKIAKELDGKAIFIHFDISKKKVQRFLEHLSIPENE--GFRVVESSEHLVNFKPENPLNLNGTYMLSFIRQVMDGTAEPELMASEPRENWHLEPIKHLTRKTYDQVVMDKTKNVFVIIYAPDCPYSREMLELLDKLGEMYKDDENVLLAKLDSSVDELPRIRVRSTPMMFLYLKDTNERI-KFHGERTIENLKKFIESNG 1455
K F V + DV F + D EL +++ + T++ + ++D + + KL + M FI ++ VP E ++ IF+ H F+ S N + E R++A E K IFI D++ +KV L++ SI E++ R++ ++E +V + + +N + +F + V DGT +P L + E E+W P+K L K +++V D++KNVFV YAP C + +++ + D+LGE YKD EN+++AK+D++ +++ + ++ P + + T ++I + G R +E KF+++ G
Sbjct: 202 KTFYDVTLIAVDVNFGITSDPELFKKYEV-KTDSLVLFKKFDERRADMPLSDETKLDKGEMISFIHSNSMRLVVPFNEENAEQIFNSKVRKHLLLFLNTTVDS----QNALVEEFREVASEFKEKVIFITVDVTAEKVNHVLKYFSISEDDVPTIRLI-NTEDVVTYAMDGS-TINKDTLRTFCQGVFDGTVKPYLKSQEIPEDWDKNPVKVLVGKNFNEVAFDESKNVFVEFYAPWCGHCQQLAPVWDELGEKYKDQENIIIAKMDATENDVEDLTIQGFPTIKYFPAGTEKKIVDYDGNRDLETFSKFLDNGG 509 HSP 2 Score: 55.4546 bits (132), Expect = 1.228e-7 Identity = 30/87 (34.48%), Postives = 45/87 (51.72%), Query Frame = 2
Query: 110 IEEDDHCLLLTDQNWDYAHKIYEYILVFFYKPDCDQCTLSDEIFVYAAKHAKETKHTVKFAFVDAANEKTIATLEQIETVPVMKFYR 370
I ED L+L N+D A +Y+LV FY P C C + I+ A K V+ A VDA EK +A+ +++ P +KF++
Sbjct: 52 ITEDKDVLILHSVNFDRALSENKYLLVEFYAPWCGHCRSLEPIYAEVAGQLKNASSEVRLAKVDAIEEKELASEFSVDSFPTLKFFK 138
BLAST of Protein disulfide-isomerase vs. Ensembl Zebrafish
Match: pdia2 (protein disulfide isomerase family A, member 2 [Source:ZFIN;Acc:ZDB-GENE-040426-705]) HSP 1 Score: 130.954 bits (328), Expect = 4.443e-32 Identity = 91/316 (28.80%), Postives = 169/316 (53.48%), Query Frame = 1
Query: 541 KDFEIVASMHDDVEFRLLKDAELCQRFNLPTTENSIGIYQ-YD---FGIQHTVSGKLTRNIMNDFI----IKHHVPIYSEFSDFIFSKSFVGHYHYFVPIIFKSFPIPLNEMKAEIRKIAKELDGKAIFIHFDISKKKVQRFLEHLSIPENE--GFRVVESSEHLVNFKPENPLNLNGTYMLSFIRQVMDGTAEPELMASEPRENWHLEPIKHLTRKTYDQVVMDKTKNVFVIIYAPDCPYSREMLELLDKLGEMYKDDENVLLAKLDSSVDELPRIRVRSTPMMFLYLKDTNERI-KFHGERTIENLKKFIESNG 1455
K F V + DV F + D EL +++ + T +S+ +++ +D + + KL + M FI ++ VP E ++ IF+ H F+ S N + E R++A E K IFI D++ +KV L++ SI E++ R++ ++E +V + + +N + +F + V DGT +P L + E E+W P+K L K +++V D++KNVFV YAP C + +++ + D+LGE YKD EN+++AK+D++ +++ + ++ P + + T ++I + G R +E KF+++ G
Sbjct: 202 KTFYDVTLIAVDVNFGITSDPELFKKYEVKT--DSLVLFKKFDERRADMPLSDETKLDKGEMISFIHSNSMRLVVPFNEENAEQIFNSKVRKHLLLFLNTTVDS----QNALVEEFREVASEFKEKVIFITVDVTAEKVNHVLKYFSISEDDVPTIRLI-NTEDVVTYAMDGS-TINKDTLRTFCQGVFDGTVKPYLKSQEIPEDWDKNPVKVLVGKNFNEVAFDESKNVFVEFYAPWCGHCQQLAPVWDELGEKYKDQENIIIAKMDATENDVEDLTIQGFPTIKYFPAGTEKKIVDYDGNRDLETFSKFLDNGG 509 HSP 2 Score: 55.0694 bits (131), Expect = 1.561e-7 Identity = 30/87 (34.48%), Postives = 45/87 (51.72%), Query Frame = 2
Query: 110 IEEDDHCLLLTDQNWDYAHKIYEYILVFFYKPDCDQCTLSDEIFVYAAKHAKETKHTVKFAFVDAANEKTIATLEQIETVPVMKFYR 370
I ED L+L N+D A +Y+LV FY P C C + I+ A K V+ A VDA EK +A+ +++ P +KF++
Sbjct: 52 ITEDKDVLILHSVNFDRALSENKYLLVEFYAPWCGHCRSLEPIYAEVAGQLKNASSEVRLAKVDAIEEKELASEFSVDSFPTLKFFK 138
BLAST of Protein disulfide-isomerase vs. Ensembl Zebrafish
Match: pdia4 (protein disulfide isomerase family A, member 4 [Source:ZFIN;Acc:ZDB-GENE-030131-5493]) HSP 1 Score: 74.3294 bits (181), Expect = 1.374e-13 Identity = 41/147 (27.89%), Postives = 81/147 (55.10%), Query Frame = 1
Query: 1027 PLNLNGTYMLSFIRQVMDGTAEPELMASEPRENWHLEPIKHLTRKTYDQVVMDKTKNVFVIIYAPDCPYSREMLELLDKLGEMYKDDENVLLAKLDSSVDELPRIRVRSTPMMFLYLKDTNER---IKFH-GERTIENLKKFIESNG 1455
P + + SF+ G +P ++ S+P + P+K + KT+D++VMD K+V + YAP C + +++ LG+ YK+++N+++AK+D++ +++P + +Y +N + IKF G+R +E KF+E +
Sbjct: 487 PEEFDSDVLRSFVMAFKKGKLKP-IVKSQPLPKNNKGPVKVVVGKTFDEIVMDSKKDVLIEFYAPWCGHCKKLEPDYISLGKKYKNEKNLVIAKMDATANDVPHDSYKVEGFPTIYFAPSNNKQNPIKFEGGKRDVEEFSKFVEKHA 632 HSP 2 Score: 50.447 bits (119), Expect = 4.066e-6 Identity = 32/114 (28.07%), Postives = 49/114 (42.98%), Query Frame = 2
Query: 131 LLLTDQNWDYAHKIYEYILVFFYKPDCDQCTLSDEIFVYAAKHAKETKHTVKFAFVDAANEKTIATLEQIETVPVMKFYRNKTGVQYLRTQGKEEVIQWLTDRVNYELKPISTL 472
L+LT N+D + ILV FY P C C + AAK + A VDA E +AT + P +K +R Y + K ++ +++D+ K + TL
Sbjct: 177 LVLTKDNFDDVVNNADIILVEFYAPWCGHCKRLAPEYEKAAKELSNRTPPIPLAKVDATAESDLATRFGVSGYPTLKIFRKGKAFDYNGPREKFGIVDYMSDQAGPPSKQVQTL 290
BLAST of Protein disulfide-isomerase vs. Ensembl Xenopus
Match: p4hb (prolyl 4-hydroxylase subunit beta [Source:NCBI gene;Acc:395048]) HSP 1 Score: 150.984 bits (380), Expect = 6.276e-47 Identity = 95/335 (28.36%), Postives = 171/335 (51.04%), Query Frame = 1
Query: 556 VASMHDDVEFRLLKDAELCQRFNLPTTENSIGIYQ-YDFGIQHTVSGKLTRNIMNDFIIKHHVPIYSEFSD----FIFSKSFVGHYHYFVPIIFKSFPIPLNEMKAEIRKIAKELDGKAIFIHFDISKKKVQRFLEHLSIPENE--GFRVVESSEHLVNFKPENPLNLNGTYMLSFIRQVMDGTAEPELMASEPRENWHLEPIKHLTRKTYDQVVMDKTKNVFVIIYAPDCPYSREMLELLDKLGEMYKDDENVLLAKLDSSVDELPRIRVRSTPMMFLYLKDTNERIK-FHGERTIENLKKFIESNGQDGNEQQFLE-IDHLQHARLTENGLVH 1533
A DD+ F + ++ L ++ I +++ +D G ++ G +T+ + FI + +P+ EF++ IF H +F+P + L + K K A GK +FI D QR LE + + E R++ E + +KPE+ +L+ + F ++G +P LM+ + ++W P+K L K +++VV ++ KNVFV YAP C + +++ + D+LGE YKD EN+++AK+DS+ +E+ +++ S P + + + + ++GERT+E KF+ES GQDG + LE ++ + L E H
Sbjct: 192 AAEAVDDIPFGITSSEAAFSKYEL--GKDGIVLFKKFDEG-RNAYEGDITKEEVLSFIKANRLPLVIEFTEQTAPMIFGGEIKTHILFFLPKSASDYKEKLEDFK----KAAASFKGKILFIFIDSDHTDNQRILEFFGLKKEECPAVRLITLEEEMTKYKPESA-DLSAEAIKEFCDSFLEGKVKPHLMSQDVSDDWDKNPVKILVGKNFEEVVFNEEKNVFVEFYAPWCGHCKQLAPIWDQLGEKYKDHENIIIAKMDSTANEIEAVKIHSFPTLKFFPAGPGKNVADYNGERTLEGFSKFLESGGQDGAADEDLEDLEDADESDLEEGDEAH 518 HSP 2 Score: 57.7658 bits (138), Expect = 6.276e-47 Identity = 44/159 (27.67%), Postives = 68/159 (42.77%), Query Frame = 2
Query: 11 VFHHNFIMSKSLITFALFSLSLSFYCNGDEIPIIEEDDHCLLLTDQNWDYAHKIYEYILVFFYKPDCDQCTLSDEIFVYAAKHAKETKHTVKFAFVDAANEKTIATLEQIETVPVMKFYRNK---TGVQYLRTQGKEEVIQWLTDRVNYELKPISTLDD 478
V + IM ++++ LF SL + I E+ L+L N+D A K Y +ILV FY P C C + AA K ++ VDA E +A + P +KF++N + +Y + +++ WL R STL D
Sbjct: 11 VLYTRLIMMRAVL---LFGCSLLIVARAN----IPEERDVLVLKKDNFDEALKQYPFILVEFYAPWCGHCKALAPEYEKAAGVLKSEGLPIRLGKVDATEESDLAQEFGVRGYPTIKFFKNGDKASPKEYSAGREAADIVNWLKKRTG---PAASTLGD 159
BLAST of Protein disulfide-isomerase vs. Ensembl Xenopus
Match: p4hb (prolyl 4-hydroxylase subunit beta [Source:NCBI gene;Acc:395048]) HSP 1 Score: 151.369 bits (381), Expect = 1.248e-46 Identity = 95/335 (28.36%), Postives = 171/335 (51.04%), Query Frame = 1
Query: 556 VASMHDDVEFRLLKDAELCQRFNLPTTENSIGIYQ-YDFGIQHTVSGKLTRNIMNDFIIKHHVPIYSEFSD----FIFSKSFVGHYHYFVPIIFKSFPIPLNEMKAEIRKIAKELDGKAIFIHFDISKKKVQRFLEHLSIPENE--GFRVVESSEHLVNFKPENPLNLNGTYMLSFIRQVMDGTAEPELMASEPRENWHLEPIKHLTRKTYDQVVMDKTKNVFVIIYAPDCPYSREMLELLDKLGEMYKDDENVLLAKLDSSVDELPRIRVRSTPMMFLYLKDTNERIK-FHGERTIENLKKFIESNGQDGNEQQFLE-IDHLQHARLTENGLVH 1533
A DD+ F + ++ L ++ I +++ +D G ++ G +T+ + FI + +P+ EF++ IF H +F+P + L + K K A GK +FI D QR LE + + E R++ E + +KPE+ +L+ + F ++G +P LM+ + ++W P+K L K +++VV ++ KNVFV YAP C + +++ + D+LGE YKD EN+++AK+DS+ +E+ +++ S P + + + + ++GERT+E KF+ES GQDG + LE ++ + L E H
Sbjct: 172 AAEAVDDIPFGITSSEAAFSKYEL--GKDGIVLFKKFDEG-RNAYEGDITKEEVLSFIKANRLPLVIEFTEQTAPMIFGGEIKTHILFFLPKSASDYKEKLEDFK----KAAASFKGKILFIFIDSDHTDNQRILEFFGLKKEECPAVRLITLEEEMTKYKPESA-DLSAEAIKEFCDSFLEGKVKPHLMSQDVSDDWDKNPVKILVGKNFEEVVFNEEKNVFVEFYAPWCGHCKQLAPIWDQLGEKYKDHENIIIAKMDSTANEIEAVKIHSFPTLKFFPAGPGKNVADYNGERTLEGFSKFLESGGQDGAADEDLEDLEDADESDLEEGDEAH 498 HSP 2 Score: 56.6102 bits (135), Expect = 1.248e-46 Identity = 42/145 (28.97%), Postives = 61/145 (42.07%), Query Frame = 2
Query: 53 FALFSLSLSFYCNGDEIPIIEEDDHCLLLTDQNWDYAHKIYEYILVFFYKPDCDQCTLSDEIFVYAAKHAKETKHTVKFAFVDAANEKTIATLEQIETVPVMKFYRNK---TGVQYLRTQGKEEVIQWLTDRVNYELKPISTLDD 478
F LF SL + I E+ L+L N+D A K Y +ILV FY P C C + AA K ++ VDA E +A + P +KF++N + +Y + +++ WL R STL D
Sbjct: 2 FLLFGCSLLIVARAN----IPEERDVLVLKKDNFDEALKQYPFILVEFYAPWCGHCKALAPEYEKAAGVLKSEGLPIRLGKVDATEESDLAQEFGVRGYPTIKFFKNGDKASPKEYSAGREAADIVNWLKKRTG---PAASTLGD 139
BLAST of Protein disulfide-isomerase vs. Ensembl Xenopus
Match: p4hb (prolyl 4-hydroxylase subunit beta [Source:NCBI gene;Acc:395048]) HSP 1 Score: 151.369 bits (381), Expect = 3.454e-46 Identity = 94/334 (28.14%), Postives = 168/334 (50.30%), Query Frame = 1
Query: 556 VASMHDDVEFRLLKDAELCQRFNLPTTENSIGIYQYDFGIQHTVSGKLTRNIMNDFIIKHHVPIYSEFSD----FIFSKSFVGHYHYFVPIIFKSFPIPLNEMKAEIRKIAKELDGKAIFIHFDISKKKVQRFLEHLSIPENE--GFRVVESSEHLVNFKPENPLNLNGTYMLSFIRQVMDGTAEPELMASEPRENWHLEPIKHLTRKTYDQVVMDKTKNVFVIIYAPDCPYSREMLELLDKLGEMYKDDENVLLAKLDSSVDELPRIRVRSTPMMFLYLKDTNERIK-FHGERTIENLKKFIESNGQDGNEQQFLE-IDHLQHARLTENGLVH 1533
A DD+ F + ++ L + + ++D G ++ G +T+ + FI + +P+ EF++ IF H +F+P + L + K K A GK +FI D QR LE + + E R++ E + +KPE+ +L+ + F ++G +P LM+ + ++W P+K L K +++VV ++ KNVFV YAP C + +++ + D+LGE YKD EN+++AK+DS+ +E+ +++ S P + + + + ++GERT+E KF+ES GQDG + LE ++ + L E H
Sbjct: 165 AAEAVDDIPFGITSSEAAFSKYEL-GKDGIVLFKKFDEG-RNAYEGDITKEEVLSFIKANRLPLVIEFTEQTAPMIFGGEIKTHILFFLPKSASDYKEKLEDFK----KAAASFKGKILFIFIDSDHTDNQRILEFFGLKKEECPAVRLITLEEEMTKYKPES-ADLSAEAIKEFCDSFLEGKVKPHLMSQDVSDDWDKNPVKILVGKNFEEVVFNEEKNVFVEFYAPWCGHCKQLAPIWDQLGEKYKDHENIIIAKMDSTANEIEAVKIHSFPTLKFFPAGPGKNVADYNGERTLEGFSKFLESGGQDGAADEDLEDLEDADESDLEEGDEAH 491 HSP 2 Score: 55.0694 bits (131), Expect = 3.454e-46 Identity = 37/126 (29.37%), Postives = 55/126 (43.65%), Query Frame = 2
Query: 110 IEEDDHCLLLTDQNWDYAHKIYEYILVFFYKPDCDQCTLSDEIFVYAAKHAKETKHTVKFAFVDAANEKTIATLEQIETVPVMKFYRNK---TGVQYLRTQGKEEVIQWLTDRVNYELKPISTLDD 478
I E+ L+L N+D A K Y +ILV FY P C C + AA K ++ VDA E +A + P +KF++N + +Y + +++ WL R STL D
Sbjct: 10 IPEERDVLVLKKDNFDEALKQYPFILVEFYAPWCGHCKALAPEYEKAAGVLKSEGLPIRLGKVDATEESDLAQEFGVRGYPTIKFFKNGDKASPKEYSAGREAADIVNWLKKRTG---PAASTLGD 132
BLAST of Protein disulfide-isomerase vs. Ensembl Xenopus
Match: p4hb (prolyl 4-hydroxylase subunit beta [Source:NCBI gene;Acc:395048]) HSP 1 Score: 151.754 bits (382), Expect = 1.226e-39 Identity = 95/335 (28.36%), Postives = 171/335 (51.04%), Query Frame = 1
Query: 556 VASMHDDVEFRLLKDAELCQRFNLPTTENSIGIYQ-YDFGIQHTVSGKLTRNIMNDFIIKHHVPIYSEFSD----FIFSKSFVGHYHYFVPIIFKSFPIPLNEMKAEIRKIAKELDGKAIFIHFDISKKKVQRFLEHLSIPENE--GFRVVESSEHLVNFKPENPLNLNGTYMLSFIRQVMDGTAEPELMASEPRENWHLEPIKHLTRKTYDQVVMDKTKNVFVIIYAPDCPYSREMLELLDKLGEMYKDDENVLLAKLDSSVDELPRIRVRSTPMMFLYLKDTNERIK-FHGERTIENLKKFIESNGQDGNEQQFLE-IDHLQHARLTENGLVH 1533
A DD+ F + ++ L ++ I +++ +D G ++ G +T+ + FI + +P+ EF++ IF H +F+P + L + K K A GK +FI D QR LE + + E R++ E + +KPE+ +L+ + F ++G +P LM+ + ++W P+K L K +++VV ++ KNVFV YAP C + +++ + D+LGE YKD EN+++AK+DS+ +E+ +++ S P + + + + ++GERT+E KF+ES GQDG + LE ++ + L E H
Sbjct: 144 AAEAVDDIPFGITSSEAAFSKYEL--GKDGIVLFKKFDEG-RNAYEGDITKEEVLSFIKANRLPLVIEFTEQTAPMIFGGEIKTHILFFLPKSASDYKEKLEDFK----KAAASFKGKILFIFIDSDHTDNQRILEFFGLKKEECPAVRLITLEEEMTKYKPES-ADLSAEAIKEFCDSFLEGKVKPHLMSQDVSDDWDKNPVKILVGKNFEEVVFNEEKNVFVEFYAPWCGHCKQLAPIWDQLGEKYKDHENIIIAKMDSTANEIEAVKIHSFPTLKFFPAGPGKNVADYNGERTLEGFSKFLESGGQDGAADEDLEDLEDADESDLEEGDEAH 470
BLAST of Protein disulfide-isomerase vs. Ensembl Xenopus
Match: p4hb (prolyl 4-hydroxylase subunit beta [Source:NCBI gene;Acc:395048]) HSP 1 Score: 151.369 bits (381), Expect = 1.292e-39 Identity = 95/335 (28.36%), Postives = 171/335 (51.04%), Query Frame = 1
Query: 556 VASMHDDVEFRLLKDAELCQRFNLPTTENSIGIYQ-YDFGIQHTVSGKLTRNIMNDFIIKHHVPIYSEFSD----FIFSKSFVGHYHYFVPIIFKSFPIPLNEMKAEIRKIAKELDGKAIFIHFDISKKKVQRFLEHLSIPENE--GFRVVESSEHLVNFKPENPLNLNGTYMLSFIRQVMDGTAEPELMASEPRENWHLEPIKHLTRKTYDQVVMDKTKNVFVIIYAPDCPYSREMLELLDKLGEMYKDDENVLLAKLDSSVDELPRIRVRSTPMMFLYLKDTNERIK-FHGERTIENLKKFIESNGQDGNEQQFLE-IDHLQHARLTENGLVH 1533
A DD+ F + ++ L ++ I +++ +D G ++ G +T+ + FI + +P+ EF++ IF H +F+P + L + K K A GK +FI D QR LE + + E R++ E + +KPE+ +L+ + F ++G +P LM+ + ++W P+K L K +++VV ++ KNVFV YAP C + +++ + D+LGE YKD EN+++AK+DS+ +E+ +++ S P + + + + ++GERT+E KF+ES GQDG + LE ++ + L E H
Sbjct: 138 AAEAVDDIPFGITSSEAAFSKYEL--GKDGIVLFKKFDEG-RNAYEGDITKEEVLSFIKANRLPLVIEFTEQTAPMIFGGEIKTHILFFLPKSASDYKEKLEDFK----KAAASFKGKILFIFIDSDHTDNQRILEFFGLKKEECPAVRLITLEEEMTKYKPES-ADLSAEAIKEFCDSFLEGKVKPHLMSQDVSDDWDKNPVKILVGKNFEEVVFNEEKNVFVEFYAPWCGHCKQLAPIWDQLGEKYKDHENIIIAKMDSTANEIEAVKIHSFPTLKFFPAGPGKNVADYNGERTLEGFSKFLESGGQDGAADEDLEDLEDADESDLEEGDEAH 464
BLAST of Protein disulfide-isomerase vs. Ensembl Mouse
Match: P4hb (prolyl 4-hydroxylase, beta polypeptide [Source:MGI Symbol;Acc:MGI:97464]) HSP 1 Score: 161.384 bits (407), Expect = 3.595e-49 Identity = 97/318 (30.50%), Postives = 168/318 (52.83%), Query Frame = 1
Query: 532 DDIKDFEIVASMHDDVEFRLLKDAELCQRFNLPTTENSIGIYQYDFGIQHTVSGKLTRNIMNDFIIKHHVPIYSEFSDFIFSKSFVG----HYHYFVPIIFKSFPIPLNEMKAEIRKIAKELDGKAIFIHFDISKKKVQRFLEHLSIPENE--GFRVVESSEHLVNFKPENPLNLNGTYMLSFIRQVMDGTAEPELMASEPRENWHLEPIKHLTRKTYDQVVMDKTKNVFVIIYAPDCPYSREMLELLDKLGEMYKDDENVLLAKLDSSVDELPRIRVRSTPMMFLYLKDTNER-IKFHGERTIENLKKFIESNGQDG 1464
D K F + A DD+ F + ++ + ++ L + + ++D G ++ G++T+ + DFI + +P+ EF++ K F G H F+P + L+ K + A+ GK +FI D QR LE + + E R++ E + +KPE+ L + F + ++G +P LM+ E E+W +P+K L +++V D+ KNVFV YAP C + +++ + DKLGE YKD EN+++AK+DS+ +E+ ++V S P + + + I ++GERT++ KKF+ES GQDG
Sbjct: 169 DSAKQFLLAAEAIDDIPFGITSNSGVFSKYQL-DKDGVVLFKKFDEG-RNNFEGEITKEKLLDFIKHNQLPLVIEFTEQTAPKIFGGEIKTHILLFLPKSVSDYDGKLSSFK----RAAEGFKGKILFIFIDSDHTDNQRILEFFGLKKEECPAVRLITLEEEMTKYKPESD-ELTAEKITEFCHRFLEGKIKPHLMSQEVPEDWDKQPVKVLVGANFEEVAFDEKKNVFVEFYAPWCGHCKQLAPIWDKLGETYKDHENIIIAKMDSTANEVEAVKVHSFPTLKFFPASADRTVIDYNGERTLDGFKKFLESGGQDG 479 HSP 2 Score: 54.6842 bits (130), Expect = 3.595e-49 Identity = 38/140 (27.14%), Postives = 66/140 (47.14%), Query Frame = 2
Query: 110 IEEDDHCLLLTDQNWDYAHKIYEYILVFFYKPDCDQCTLSDEIFVYAAKHAKETKHTVKFAFVDAANEKTIATLEQIETVPVMKFYRNK-TGVQYLRTQGKE--EVIQWLTDRVNYELKPISTLDDGKNTLLNNLLVVFG 520
+EE+D+ L+L N++ A ++Y+LV FY P C C + AA K ++ A VDA E +A + P +KF++N T T G+E +++ WL R +S ++ + ++ + V G
Sbjct: 22 LEEEDNVLVLKKSNFEEALAAHKYLLVEFYAPWCGHCKALAPEYAKAAAKLKAEGSEIRLAKVDATEESDLAQQYGVRGYPTIKFFKNGDTASPKEYTAGREADDIVNWLKKRTGPAATTLSDTAAAESLVDSSEVTVIG 161
BLAST of Protein disulfide-isomerase vs. Ensembl Mouse
Match: Pdia2 (protein disulfide isomerase associated 2 [Source:MGI Symbol;Acc:MGI:1916441]) HSP 1 Score: 107.457 bits (267), Expect = 3.538e-29 Identity = 80/317 (25.24%), Postives = 145/317 (45.74%), Query Frame = 1
Query: 535 DIKDFEIVASMHDDVEFRLLKDAELCQRFNLPTTENSIGIYQYDFGIQHTVSGKLTRNIMND---FIIKHHVPIYSEF----SDFIFSKSFVGHYHYFVPIIFKSFPIPLNEMKAEIRKIAKELDGKAIFIHFDISKKKVQRFLEHLSIPENEG--FRVVESSEHLVNFKPENPLNLNGTYMLSFIRQVMDGTAEPELMASEPRENWHLEPIKHLTRKTYDQVVMDKTKNVFVIIYAPDCPYSREMLELLDKLGEMYKDDENVLLAKLDSSVDELPRIRVRSTPMMFLYLKDTNER-IKFHGERTIENLKKFIESNG 1455
D+ F +A D+ F +L ++F L T + + ++D G K T + D F++ H + + +EF S IF+ + H FV E+ + R+ A G+ +F+ D++ L + + E R++ + E + P + + + +F + V+ G + L++ E +W P+K L K ++QV D+TKNVFV YAP C + +EM + L E YKD E++++A+LD++ +EL V P + + + + I + R +E KF++S G
Sbjct: 186 DMATFLALAKDALDMTFGFTDQPQLFEKFGL-TKDTVVLFKKFDEGRADFPVDKETGLDLGDLSRFLVIHSMHLVTEFNSQTSPKIFAAKILNHLLLFVNQTLAQH----RELLTDFREAAPPFRGQVLFVMVDVAADN-SHVLNYFGLKAEEAPTLRLI-NVETTKKYAPTGVIAITAASVAAFCQAVLHGEIKHYLLSQEIPPDWDQGPVKTLVSKNFEQVAFDETKNVFVKFYAPWCSHCKEMAPAWEALAEKYKDREDIVIAELDATANELEAFSVLGYPTLKFFPAGPDRKVIDYKSTRDLETFSKFLDSGG 495 HSP 2 Score: 41.2022 bits (95), Expect = 3.538e-29 Identity = 30/121 (24.79%), Postives = 51/121 (42.15%), Query Frame = 2
Query: 92 GDEIPIIEEDDHCLLLTDQNWDYAHKIYEYILVFFYKPDCDQCTLSDEIFVYAAKHAKETKHTVKFAFVDAANEKTIATLEQIETVPVMKFYRNKTGV---QYLRTQGKEEVIQWLTDRVN 445
G+E+P ++D L+L + A + + ++V FY P C C + AA V A VD E + ++ P +KF++N +Y + E + +WL RV
Sbjct: 38 GEEVP---KEDGILVLNHRTLSLALQEHSALMVEFYAPWCGHCKELAPEYSKAAALLAAESAVVTLAKVDGPAEPELTKEFEVVGYPTLKFFQNGNRTNPEEYAGPKTAEGIAEWLRRRVG 155
BLAST of Protein disulfide-isomerase vs. Ensembl Mouse
Match: Pdia2 (protein disulfide isomerase associated 2 [Source:MGI Symbol;Acc:MGI:1916441]) HSP 1 Score: 107.457 bits (267), Expect = 3.567e-29 Identity = 80/317 (25.24%), Postives = 145/317 (45.74%), Query Frame = 1
Query: 535 DIKDFEIVASMHDDVEFRLLKDAELCQRFNLPTTENSIGIYQYDFGIQHTVSGKLTRNIMND---FIIKHHVPIYSEF----SDFIFSKSFVGHYHYFVPIIFKSFPIPLNEMKAEIRKIAKELDGKAIFIHFDISKKKVQRFLEHLSIPENEG--FRVVESSEHLVNFKPENPLNLNGTYMLSFIRQVMDGTAEPELMASEPRENWHLEPIKHLTRKTYDQVVMDKTKNVFVIIYAPDCPYSREMLELLDKLGEMYKDDENVLLAKLDSSVDELPRIRVRSTPMMFLYLKDTNER-IKFHGERTIENLKKFIESNG 1455
D+ F +A D+ F +L ++F L T + + ++D G K T + D F++ H + + +EF S IF+ + H FV E+ + R+ A G+ +F+ D++ L + + E R++ + E + P + + + +F + V+ G + L++ E +W P+K L K ++QV D+TKNVFV YAP C + +EM + L E YKD E++++A+LD++ +EL V P + + + + I + R +E KF++S G
Sbjct: 189 DMATFLALAKDALDMTFGFTDQPQLFEKFGL-TKDTVVLFKKFDEGRADFPVDKETGLDLGDLSRFLVIHSMHLVTEFNSQTSPKIFAAKILNHLLLFVNQTLAQH----RELLTDFREAAPPFRGQVLFVMVDVAADN-SHVLNYFGLKAEEAPTLRLI-NVETTKKYAPTGVIAITAASVAAFCQAVLHGEIKHYLLSQEIPPDWDQGPVKTLVSKNFEQVAFDETKNVFVKFYAPWCSHCKEMAPAWEALAEKYKDREDIVIAELDATANELEAFSVLGYPTLKFFPAGPDRKVIDYKSTRDLETFSKFLDSGG 498 HSP 2 Score: 41.2022 bits (95), Expect = 3.567e-29 Identity = 30/121 (24.79%), Postives = 51/121 (42.15%), Query Frame = 2
Query: 92 GDEIPIIEEDDHCLLLTDQNWDYAHKIYEYILVFFYKPDCDQCTLSDEIFVYAAKHAKETKHTVKFAFVDAANEKTIATLEQIETVPVMKFYRNKTGV---QYLRTQGKEEVIQWLTDRVN 445
G+E+P ++D L+L + A + + ++V FY P C C + AA V A VD E + ++ P +KF++N +Y + E + +WL RV
Sbjct: 38 GEEVP---KEDGILVLNHRTLSLALQEHSALMVEFYAPWCGHCKELAPEYSKAAALLAAESAVVTLAKVDGPAEPELTKEFEVVGYPTLKFFQNGNRTNPEEYAGPKTAEGIAEWLRRRVG 155
BLAST of Protein disulfide-isomerase vs. Ensembl Mouse
Match: Pdia2 (protein disulfide isomerase associated 2 [Source:MGI Symbol;Acc:MGI:1916441]) HSP 1 Score: 85.1149 bits (209), Expect = 5.121e-19 Identity = 40/112 (35.71%), Postives = 64/112 (57.14%), Query Frame = 1
Query: 1123 NWHLEPIKHLTRKTYDQVVMDKTKNVFVIIYAPDCPYSREMLELLDKLGEMYKDDENVLLAKLDSSVDELPRIRVRSTPMMFLYLKDTNER-IKFHGERTIENLKKFIESNG 1455
+W P+K L K ++QV D+TKNVFV YAP C + +EM + L E YKD E++++A+LD++ +EL V P + + + + I + R +E KF++S G
Sbjct: 14 DWDQGPVKTLVSKNFEQVAFDETKNVFVKFYAPWCSHCKEMAPAWEALAEKYKDREDIVIAELDATANELEAFSVLGYPTLKFFPAGPDRKVIDYKSTRDLETFSKFLDSGG 125
BLAST of Protein disulfide-isomerase vs. Ensembl Mouse
Match: Pdilt (protein disulfide isomerase-like, testis expressed [Source:MGI Symbol;Acc:MGI:1919080]) HSP 1 Score: 89.7373 bits (221), Expect = 1.985e-18 Identity = 66/237 (27.85%), Postives = 113/237 (47.68%), Query Frame = 1
Query: 754 EFSDFIFSKSFVGHYHYFVPIIFKSFPIPLNEMKAEIRKIAKELDGKAIFIHFDISKKKVQRFLEHLSIPENEGFRVVESSEHLVNFKPENPL-----NLNGTYMLSFIRQVMDGTAEPELMASEPRENWHLEPIKHLTRKTYDQVVMDKTKNVFVIIYAPDCPYSREMLELLDKLGEMYKDDENVLLAKLDSSVDELPRIRVRSTPMMFLYLKDTNERIKFHGERTIENLKKFIES 1449
E D I+ + + H F I KS P + + R+IAKE K +F+ + + K +R E+ I RV S ++N + ++N + F + TA+ + E + W P+K L K ++ VV+DK K+VFV+ YAP R +L LL++LG Y++ V++AK+D + +++ P L+ D+ E + + GE T++ F+ES
Sbjct: 261 ENKDLIYELNILNHMLLF---ISKSSE-PYSTISRHYRQIAKEFQNKILFVLVNADEPKNKRIFEYFQIS-----RVNVPSVQILNLSSDGRYKMPTDDINFESLKKFCNSFLSKTAKKHKASEEIPKYWDQGPVKKLVGKNFNVVVLDKEKDVFVMFYAPWSEKCRVLLPLLEELGIKYQNHSTVIIAKIDITANDIQLANPEQYPFFRLFPTDSQEAVMYKGEHTMKGFCDFLES 488
BLAST of Protein disulfide-isomerase vs. UniProt/SwissProt
Match: sp|P05307|PDIA1_BOVIN (Protein disulfide-isomerase OS=Bos taurus OX=9913 GN=P4HB PE=1 SV=1) HSP 1 Score: 159.073 bits (401), Expect = 4.282e-51 Identity = 96/316 (30.38%), Postives = 169/316 (53.48%), Query Frame = 1
Query: 532 DDIKDFEIVASMHDDVEFRLLKDAELCQRFNLPTTENSIGIYQYDFGIQHTVSGKLTRNIMNDFIIKHHVPIYSEFSDFIFSKSFVG----HYHYFVPIIFKSFPIPLNEMKAEIRKIAKELDGKAIFIHFDISKKKVQRFLEHLSIPENE--GFRVVESSEHLVNFKPENPLNLNGTYMLSFIRQVMDGTAEPELMASEPRENWHLEPIKHLTRKTYDQVVMDKTKNVFVIIYAPDCPYSREMLELLDKLGEMYKDDENVLLAKLDSSVDELPRIRVRSTPMMFLYLKDTNER-IKFHGERTIENLKKFIESNGQ 1458
D K F + A + DD+ F + ++++ ++ L + + ++D G ++ G++T+ + DFI + +P+ EF++ K F G H F+P + L+ K K A+ GK +FI D QR LE + + E R++ E + +KPE+ L + F + ++G +P LM+ E ++W +P+K L K +++V D+ KNVFV YAP C + +++ + DKLGE YKD EN+++AK+DS+ +E+ ++V S P + + + I ++GERT++ KKF+ES GQ
Sbjct: 169 DSAKQFFLAAEVIDDIPFGITSNSDVFSKYQL-DKDGVVLFKKFDEG-RNNFEGEVTKEKLLDFIKHNQLPLVIEFTEQTAPKIFGGEIKTHILLFLPKSVSDYEGKLSNFK----KAAESFKGKILFIFIDSDHTDNQRILEFFGLKKEECPAVRLITLEEEMTKYKPESD-ELTAEKITEFCHRFLEGKIKPHLMSQELPDDWDKQPVKVLVGKNFEEVAFDEKKNVFVEFYAPWCGHCKQLAPIWDKLGETYKDHENIVIAKMDSTANEVEAVKVHSFPTLKFFPASADRTVIDYNGERTLDGFKKFLESGGQ 477 HSP 2 Score: 65.855 bits (159), Expect = 4.282e-51 Identity = 41/126 (32.54%), Postives = 60/126 (47.62%), Query Frame = 2
Query: 113 EEDDHCLLLTDQNWDYAHKIYEYILVFFYKPDCDQCTLSDEIFVYAAKHAKETKHTVKFAFVDAANEKTIATLEQIETVPVMKFYRNK-TGVQYLRTQGKE--EVIQWLTDRVNYELKPISTLDDG 481
+E+DH L+L N+D A ++Y+LV FY P C C + AA K ++ A VDA E +A + P +KF++N T T G+E +++ WL R STL DG
Sbjct: 23 DEEDHVLVLHKGNFDEALAAHKYLLVEFYAPWCGHCKALAPEYAKAAGKLKAEGSEIRLAKVDATEESDLAQQYGVRGYPTIKFFKNGDTASPKEYTAGREADDIVNWLKKRTG---PAASTLSDG 145
BLAST of Protein disulfide-isomerase vs. UniProt/SwissProt
Match: sp|P09102|PDIA1_CHICK (Protein disulfide-isomerase OS=Gallus gallus OX=9031 GN=P4HB PE=1 SV=3) HSP 1 Score: 163.696 bits (413), Expect = 1.267e-50 Identity = 97/318 (30.50%), Postives = 170/318 (53.46%), Query Frame = 1
Query: 532 DDIKDFEIVASMHDDVEFRLLKDAELCQRFNLPTTENSIGIYQYDFGIQHTVSGKLTRNIMNDFIIKHHVPIYSEFSDFIFSKSFVG----HYHYFVPIIFKSFPIPLNEMKAEIRKIAKELDGKAIFIHFDISKKKVQRFLEHLSIPENE--GFRVVESSEHLVNFKPENPLNLNGTYMLSFIRQVMDGTAEPELMASEPRENWHLEPIKHLTRKTYDQVVMDKTKNVFVIIYAPDCPYSREMLELLDKLGEMYKDDENVLLAKLDSSVDELPRIRVRSTPMMFLYLKDTNER-IKFHGERTIENLKKFIESNGQDG 1464
D K+F + A DD+ F + A++ ++ L + + + ++D G ++ G LT++ + +FI + +P+ EF++ K F G H F+P + L+ K A GK +FI D QR LE + + E R++ E + +KPE+ +L + F + ++G +P LM+ + E+W +P+K L K +++V D+ KNVFV YAP C + +++ + DKLGE Y+D EN+++AK+DS+ +E+ +++ S P + + + I ++GERT+E KKF+ES GQDG
Sbjct: 172 DAAKEFLLAAESVDDIPFGISSSADVFSKYQL-SQDGVVLFKKFDEG-RNNFEGDLTKDNLLNFIKSNQLPLVIEFTEQTAPKIFGGEIKTHILLFLPKSVSDYEGKLDNFKT----AAGNFKGKILFIFIDSDHSDNQRILEFFGLKKEECPAVRLITLEEEMTKYKPESD-DLTADKIKEFCNKFLEGKIKPHLMSQDLPEDWDKQPVKVLVGKNFEEVAFDENKNVFVEFYAPWCGHCKQLAPIWDKLGETYRDHENIVIAKMDSTANEVEAVKIHSFPTLKFFPAGSGRNVIDYNGERTLEGFKKFLESGGQDG 482 HSP 2 Score: 59.6918 bits (143), Expect = 1.267e-50 Identity = 32/115 (27.83%), Postives = 53/115 (46.09%), Query Frame = 2
Query: 110 IEEDDHCLLLTDQNWDYAHKIYEYILVFFYKPDCDQCTLSDEIFVYAAKHAKETKHTVKFAFVDAANEKTIATLEQIETVPVMKFYRNKTGV---QYLRTQGKEEVIQWLTDRVN 445
+EE+D L+L N++ A + ++LV FY P C C + AA K ++ A VDA E +A + P +KF+RN +Y + ++++ WL R
Sbjct: 25 LEEEDGVLVLRAANFEQALAAHRHLLVEFYAPWCGHCKALAPEYAKAAAQLKAEGSEIRLAKVDATEEAELAQQFGVRGYPTIKFFRNGDKAAPREYTAGREADDIVSWLKKRTG 139
BLAST of Protein disulfide-isomerase vs. UniProt/SwissProt
Match: sp|Q2HWU2|PDIA1_MACFU (Protein disulfide-isomerase OS=Macaca fuscata fuscata OX=9543 GN=P4HB PE=2 SV=1) HSP 1 Score: 156.762 bits (395), Expect = 3.177e-50 Identity = 97/316 (30.70%), Postives = 166/316 (52.53%), Query Frame = 1
Query: 532 DDIKDFEIVASMHDDVEFRLLKDAELCQRFNLPTTENSIGIYQYDFGIQHTVSGKLTRNIMNDFIIKHHVPIYSEFSDFIFSKSFVG----HYHYFVPIIFKSFPIPLNEMKAEIRKIAKELDGKAIFIHFDISKKKVQRFLEHLSIPENE--GFRVVESSEHLVNFKPENPLNLNGTYMLSFIRQVMDGTAEPELMASEPRENWHLEPIKHLTRKTYDQVVMDKTKNVFVIIYAPDCPYSREMLELLDKLGEMYKDDENVLLAKLDSSVDELPRIRVRSTPMMFLYLKDTNER-IKFHGERTIENLKKFIESNGQ 1458
D K F A DD+ F + ++++ ++ L + + ++D G ++ G++T+ + DFI + +P+ EF++ K F G H F+P + L+ K A+ GK +FI D QR LE + + E R++ E + +KPE+ L + F + ++G +P LM+ E E+W +P+K L K +++V D+ KNVFV YAP C + +++ + DKLGE YKD EN+++AK+DS+ +E+ I+V S P + + + I ++GERT++ KKF+ES GQ
Sbjct: 169 DSAKQFLQAAEAIDDIPFGITSNSDVFSKYQL-DKDGVVLFKKFDEG-RNNFEGEVTKENLLDFIKYNQLPLVIEFTEQTAPKIFGGEIKTHILLFLPKSVSDYDGKLSNFKT----AAESFKGKILFIFIDSDHTDNQRILEFFGLKKEECPAVRLITLEEEMTKYKPESD-ELTAERITEFCHRFLEGKIKPHLMSQELPEDWDKQPVKVLVGKNFEEVAFDENKNVFVEFYAPWCGHCKQLAPIWDKLGETYKDHENIVIAKMDSTANEVEAIKVHSFPTLKFFPASVDRTVIDYNGERTLDGFKKFLESGGQ 477 HSP 2 Score: 65.0846 bits (157), Expect = 3.177e-50 Identity = 41/126 (32.54%), Postives = 59/126 (46.83%), Query Frame = 2
Query: 113 EEDDHCLLLTDQNWDYAHKIYEYILVFFYKPDCDQCTLSDEIFVYAAKHAKETKHTVKFAFVDAANEKTIATLEQIETVPVMKFYRNK-TGVQYLRTQGKE--EVIQWLTDRVNYELKPISTLDDG 481
EE+DH L+L N+ A ++Y+LV FY P C C + AA K ++ A VDA E +A + P +KF+RN T T G+E +++ WL R +TL DG
Sbjct: 23 EEEDHVLVLRKSNFAEALAAHKYLLVEFYAPWCGHCKALAPEYAKAAGKLKAEGSEIRLAKVDATEESDLAQQYGVRGYPTIKFFRNGDTASPKEYTAGREADDIVNWLKKRTG---PAATTLPDG 145
BLAST of Protein disulfide-isomerase vs. UniProt/SwissProt
Match: sp|P07237|PDIA1_HUMAN (Protein disulfide-isomerase OS=Homo sapiens OX=9606 GN=P4HB PE=1 SV=3) HSP 1 Score: 155.992 bits (393), Expect = 6.585e-50 Identity = 96/316 (30.38%), Postives = 165/316 (52.22%), Query Frame = 1
Query: 532 DDIKDFEIVASMHDDVEFRLLKDAELCQRFNLPTTENSIGIYQYDFGIQHTVSGKLTRNIMNDFIIKHHVPIYSEFSDFIFSKSFVG----HYHYFVPIIFKSFPIPLNEMKAEIRKIAKELDGKAIFIHFDISKKKVQRFLEHLSIPENE--GFRVVESSEHLVNFKPENPLNLNGTYMLSFIRQVMDGTAEPELMASEPRENWHLEPIKHLTRKTYDQVVMDKTKNVFVIIYAPDCPYSREMLELLDKLGEMYKDDENVLLAKLDSSVDELPRIRVRSTPMMFLYLKDTNER-IKFHGERTIENLKKFIESNGQ 1458
D K F A DD+ F + ++++ ++ L + + ++D G ++ G++T+ + DFI + +P+ EF++ K F G H F+P + L+ K A+ GK +FI D QR LE + + E R++ E + +KPE+ L + F + ++G +P LM+ E E+W +P+K L K ++ V D+ KNVFV YAP C + +++ + DKLGE YKD EN+++AK+DS+ +E+ ++V S P + + + I ++GERT++ KKF+ES GQ
Sbjct: 167 DSAKQFLQAAEAIDDIPFGITSNSDVFSKYQL-DKDGVVLFKKFDEG-RNNFEGEVTKENLLDFIKHNQLPLVIEFTEQTAPKIFGGEIKTHILLFLPKSVSDYDGKLSNFKT----AAESFKGKILFIFIDSDHTDNQRILEFFGLKKEECPAVRLITLEEEMTKYKPESE-ELTAERITEFCHRFLEGKIKPHLMSQELPEDWDKQPVKVLVGKNFEDVAFDEKKNVFVEFYAPWCGHCKQLAPIWDKLGETYKDHENIVIAKMDSTANEVEAVKVHSFPTLKFFPASADRTVIDYNGERTLDGFKKFLESGGQ 475 HSP 2 Score: 65.0846 bits (157), Expect = 6.585e-50 Identity = 41/126 (32.54%), Postives = 59/126 (46.83%), Query Frame = 2
Query: 113 EEDDHCLLLTDQNWDYAHKIYEYILVFFYKPDCDQCTLSDEIFVYAAKHAKETKHTVKFAFVDAANEKTIATLEQIETVPVMKFYRNK-TGVQYLRTQGKE--EVIQWLTDRVNYELKPISTLDDG 481
EE+DH L+L N+ A ++Y+LV FY P C C + AA K ++ A VDA E +A + P +KF+RN T T G+E +++ WL R +TL DG
Sbjct: 21 EEEDHVLVLRKSNFAEALAAHKYLLVEFYAPWCGHCKALAPEYAKAAGKLKAEGSEIRLAKVDATEESDLAQQYGVRGYPTIKFFRNGDTASPKEYTAGREADDIVNWLKKRTG---PAATTLPDG 143
BLAST of Protein disulfide-isomerase vs. UniProt/SwissProt
Match: sp|Q17770|PDI2_CAEEL (Protein disulfide-isomerase 2 OS=Caenorhabditis elegans OX=6239 GN=pdi-2 PE=1 SV=1) HSP 1 Score: 151.754 bits (382), Expect = 7.904e-50 Identity = 92/317 (29.02%), Postives = 168/317 (53.00%), Query Frame = 1
Query: 532 DDIKDFEIVASMHDDVEFRLLKDAELCQRFNLPTTENSIGIYQYDFGIQHTVSGKLTRNIMNDFIIKHHVPIYSEF----SDFIFSKSFVGHYHYFVPIIFKSFPIPLNEMKAEIRKIAKELDGKAIFIHFDISKKKVQRFLEHLSIPENE--GFRVVESSEHLVNFKPENPLNLNGTYMLSFIRQVMDGTAEPELMASEPRENWHLEPIKHLTRKTYDQVVMDKTKNVFVIIYAPDCPYSREMLELLDKLGEMYKDDENVLLAKLDSSVDELPRIRVRSTPMMFLYLKDTNERIKFHGERTIENLKKFIESNGQDG 1464
DD K F VA+ DDV F + + + L E + ++D G + KLT++ + +I + + + SEF + IF H FV F +++ E + AK+ GK +F++ + ++ R +E + ++E R++ E + FKP+ + + F + +DG+ +P LM+ + E+W P+K L K ++QV D TKNV V YAP C + +++ DKLGE + DDE++++AK+DS+++E+ ++++S P + + +N+ + + G+RTIE KF+E+NG++G
Sbjct: 163 DDAKTFLEVAAGIDDVPFGISTEDAVKSEIELKG-EGIVLFKKFDDG-RVAFDEKLTQDGLKTWIQANRLALVSEFTQETASVIFGGEIKSHNLLFVSKESSEFA----KLEQEFKNAAKQFKGKVLFVYINTDVEENARIMEFFGLKKDELPAIRLISLEEDMTKFKPDFE-EITTENISKFTQNYLDGSVKPHLMSEDIPEDWDKNPVKILVGKNFEQVARDNTKNVLVEFYAPWCGHCKQLAPTWDKLGEKFADDESIVIAKMDSTLNEVEDVKIQSFPTIKFFPAGSNKVVDYTGDRTIEGFTKFLETNGKEG 472 HSP 2 Score: 68.5514 bits (166), Expect = 7.904e-50 Identity = 41/151 (27.15%), Postives = 69/151 (45.70%), Query Frame = 2
Query: 68 LSLSFYCNGDEIPIIEEDDHCLLLTDQNWDYAHKIYEYILVFFYKPDCDQCTLSDEIFVYAAKHAKETKHTVKFAFVDAANEKTIATLEQIETVPVMKFYRNKTGVQYLRTQGKEEVIQWLTDRVNYELKPISTLDDGKNTLLNNLLVVFG 520
+ L F G +IEE+++ ++LT N+D E+ILV FY P C C + AA KE +K +DA +++ ++ P +K +RN +Y + + +I WL + KP++ D K + +VV G
Sbjct: 5 VGLFFLVLGASAAVIEEEENVIVLTKDNFDEVINGNEFILVEFYAPWCGHCKSLAPEYAKAATQLKEEGSDIKLGKLDATVHGEVSSKFEVRGYPTLKLFRNGKPQEYNGGRDHDSIIAWLKKKTGPVAKPLADADAVKELQESADVVVIG 155
BLAST of Protein disulfide-isomerase vs. TrEMBL
Match: A0A455LAR4 (Protein disulfide-isomerase OS=Habrobracon hebetor OX=69819 GN=PDI PE=2 SV=1) HSP 1 Score: 163.31 bits (412), Expect = 4.628e-54 Identity = 91/302 (30.13%), Postives = 166/302 (54.97%), Query Frame = 1
Query: 571 DDVEFRLLKDAELCQRFNLPTTENSIGIYQ-YDFGIQHTVSGKLTRNIMNDFIIKHHVPIYSEFSDFIFSKSFVGHYHYFVPIIFKSFPIPLNEMKAEIRKIAKELDGKAIFIHFDISKKKVQRFLEHLSIPENE--GFRVVESSEHLVNFKPENPLNLNGTYMLSFIRQVMDGTAEPELMASEPRENWHLEPIKHLTRKTYDQVVMDKTKNVFVIIYAPDCPYSREMLELLDKLGEMYKDDENVLLAKLDSSVDELPRIRVRSTPMMFLYLKDTNERIKFHGERTIENLKKFIESNGQDGN 1467
DD F ++ D L F + + +Y+ +D G ++ G+LT + DF+ +P+ +F+ K F G + + ++ I++ AK+ G+ +F+ + + +R LE + + + R+++ + + FKPENP +L+G +L F+ +DG + LM+ + E+W EP+K L + +V DK+K+V V YAP C + +++ + DKLGE +KD+ +V++AK+D++++E+ ++ S P + LY K+TNE + ++GERT+E L KFIES G G
Sbjct: 177 DDQVFGIVSDEALFSEFE--AEDGKVVLYKKFDEG-KNVFEGELTSKALTDFVAAFSLPLVVDFNQETAQKIFGGDIKSHLLLFLSKEAGHFDKYLEGIQEPAKKFRGQVLFVTINADENDHERILEFFGMKKEDVPAMRIIKLEQDMAKFKPENP-DLDGANVLEFVTAFVDGKLKRHLMSQDLPEDWDKEPVKVLVGTNFAEVAFDKSKHVLVEFYAPWCGHCKQLAPIYDKLGEKFKDNADVVIAKMDATINEVEEAKIDSFPTLILYKKETNEAVSYNGERTLEGLSKFIESGGVYGQ 474 HSP 2 Score: 79.337 bits (194), Expect = 4.628e-54 Identity = 43/136 (31.62%), Postives = 68/136 (50.00%), Query Frame = 2
Query: 110 IEEDDHCLLLTDQNWDYAHKIYEYILVFFYKPDCDQCTLSDEIFVYAAKHAKETKHTVKFAFVDAANEKTIATLEQIETVPVMKFYRNKTGVQYLRTQGKEEVIQWLTDRVNYELKPISTLDDGKN-TLLNNLLVV 514
I+ +D L++T N++ A K +EYIL FY P C C + AAK E +K A VDA E +A + P +KFYR + Y + +++I W+ + KP++T ++ K T NN+ +V
Sbjct: 20 IKTEDEVLVITKDNFEEALKEHEYILFEFYAPWCGHCKALAPEYAKAAKRLVEQGSKIKLAKVDATQEGPLAEQHGVRGYPTLKFYRKGVAIDYTGGRQADDIITWVNKKTGPPAKPLATAEEVKEFTESNNVAIV 155
BLAST of Protein disulfide-isomerase vs. TrEMBL
Match: R7VJ39 (Protein disulfide-isomerase OS=Capitella teleta OX=283909 GN=CAPTEDRAFT_156715 PE=3 SV=1) HSP 1 Score: 166.777 bits (421), Expect = 5.646e-54 Identity = 103/318 (32.39%), Postives = 169/318 (53.14%), Query Frame = 1
Query: 529 VDDIKDFEIVASMHDDVEFRLLKDAELCQRFNLPTTENSIGIYQYDFGIQHTVSGKLTRNIMNDFIIKHHVPIYSEFSDFIFSKSFVG----HYHYFVPIIFKSFPIPLNEMKAEIRKIAKELDGKAIFIHFDISKKKVQRFLEHLSIPEN--EGFRVVESSEHLVNFKPENPLNLNGTYMLSFIRQVMDGTAEPELMASEPRENWHLEPIKHLTRKTYDQVVMDKTKNVFVIIYAPDCPYSREMLELLDKLGEMYKDDENVLLAKLDSSVDELPRIRVRSTPMMFLYLKDTNERIKFHGERTIENLKKFIESNGQDG 1464
D K F VAS +DDV F + +AE N E + ++D G ++ ++ LT + +FI + +P EF+ K F G H +F+ F ++E K K+A E GK +FI+ DI + R LE + + R + + + +KPE L+ + F+ V GT +P LM+ + E+W P+K L K +++V DKTK V V YAP C + +++ + ++LGE +KD++ V++AK+DS+ +EL ++V+S P + + KD+ E I ++GERT+E KF+ES G+DG
Sbjct: 163 TDAAKAFLAVASQYDDVPFAIT-EAEDVFTDNKVEGEAVVLFKKFDEG-RNDLTADLTEANIKEFIGANQLPTVIEFTQEAAPKIFGGDAKNHLLFFISKTSDDFQAKMDEYK----KVAPEFKGKVLFIYIDIDDEDNLRILEFFGLSPDVCPAVRYITLGDEMTKYKPETDA-LDAESIKKFVTDVRAGTVKPHLMSEDVPEDWDATPVKTLVGKNFNEVAKDKTKGVLVEFYAPWCGHCKQLAPIWEELGEKFKDNDEVVIAKMDSTANELEDVKVQSFPTIKFFPKDSEEVIDYNGERTLEGFTKFLESGGKDG 473 HSP 2 Score: 75.485 bits (184), Expect = 5.646e-54 Identity = 41/137 (29.93%), Postives = 69/137 (50.36%), Query Frame = 2
Query: 110 IEEDDHCLLLTDQNWDYAHKIYEYILVFFYKPDCDQCTLSDEIFVYAAKHAKETKHTVKFAFVDAANEKTIATLEQIETVPVMKFYRNKTGVQYLRTQGKEEVIQWLTDRVNYELKPISTLDDGKNTLLNNLLVVFG 520
I ED+ L+LT+ N+D A + ++ ILV FY P C C + AAK + T+K VDA E +AT + P +KF+RN + Y + ++ I W+ + ++T+D+ K + + +V+ G
Sbjct: 20 IAEDEGVLVLTEANFDAALEKHDAILVEFYAPWCGHCKALAPEYATAAKKLNDEGSTLKLGKVDATVETKLATKFSVRGYPTIKFFRNGNPIDYSAGRKADDFINWMKKKTGPPAVTVATVDEAKALIEKDDVVIVG 156
BLAST of Protein disulfide-isomerase vs. TrEMBL
Match: A0A2I9LPF0 (Protein disulfide-isomerase OS=Centruroides hentzi OX=88313 PE=3 SV=1) HSP 1 Score: 170.629 bits (431), Expect = 7.004e-54 Identity = 101/314 (32.17%), Postives = 173/314 (55.10%), Query Frame = 1
Query: 532 DDIKDFEIVASMHDDVEFRLLKDAELCQRFNLPTTENSIGIYQ-YDFGIQHTVSGKLTRNIMNDFIIKHHVPIYSEFSDFIFSKSFVGHYHYFVPIIFKSFPIPLNEMKAEIRKIAKELDGKAIFIHFDISKKKVQRFLEHLSIPENEG--FRVVESSEHLVNFKPENPLNLNGTYMLSFIRQVMDGTAEPELMASEPRENWHLEPIKHLTRKTYDQVVMDKTKNVFVIIYAPDCPYSREMLELLDKLGEMYKDDENVLLAKLDSSVDELPRIRVRSTPMMFLYLKDTNERIKFHGERTIENLKKFIESNGQDG 1464
D+ K + VA DD F + E+ + FN+ ++SI +++ +D G ++ G+LT + DFI + +P+ +F+ K F G + +E+ RK+AK+ K +F+ DI ++ +R +E + + + R+++ E + FKP LN + +F++ V+DG + L++ ENW P+K L +D V +DKTK+V V YAP C + +++ + +KLGE YKD N+++AK+D++ +EL ++ S P + L+ KDTNE + F+GERT+E L KFI+S G DG
Sbjct: 165 DEAKVYLDVALESDDYSFGITSQDEVFKEFNV--EKDSIVLFKKFDEG-RNDFDGELTEKALKDFINMNSLPLVVDFNQDTAQKVFGGDIKAHNLLFISKKSSEYSELVEVFRKVAKDFKKKVLFVTIDIDEEDHERIMEFFGLKKEDAPDMRLIQLEEEMTKFKPPTS-GLNEDNIRNFVQGVLDGKIKQHLLSESVPENWDKGPVKVLVGNNFDDVALDKTKDVLVEFYAPWCGHCKQLAPIYEKLGEKYKDKSNIVIAKMDATANELEHTKIHSFPTIKLFKKDTNEVVDFNGERTLEGLSKFIDSGGVDG 474 HSP 2 Score: 71.2478 bits (173), Expect = 7.004e-54 Identity = 42/144 (29.17%), Postives = 68/144 (47.22%), Query Frame = 2
Query: 47 ITFALFSLSLSFYCNGDEIPIIEEDDHCLLLTDQNWDYAHKIYEYILVFFYKPDCDQCTLSDEIFVYAAKHAKETKHTVKFAFVDAANEKTIATLEQIETVPVMKFYRNKTGVQYLRTQGKEEVIQWLTDRVNYELKPISTLDD 478
I F L L + +IP +D L+L N+D A + +++ILV FY P C C + AAK KE +K A +DA E +A + P +KF+R +Y + E++++WL ++ P +LD+
Sbjct: 3 IPFVLSVLFFTIITASGDIPT---EDEVLVLNKDNFDKAVQEHKHILVEFYAPWCGHCKALAPEYAKAAKQLKEEASEIKLAKIDATQESDLAEQYDVRGYPTLKFFRGGKPSEYKGGRVAEDIVRWLKKKIG---PPAESLDN 140
BLAST of Protein disulfide-isomerase vs. TrEMBL
Match: A0A1I8HRX2 (Protein disulfide-isomerase OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig011389g1 PE=3 SV=1) HSP 1 Score: 160.229 bits (404), Expect = 2.752e-52 Identity = 91/313 (29.07%), Postives = 174/313 (55.59%), Query Frame = 1
Query: 532 DDIKDFEIVA-SMHDDVEFRLLKDAELCQRFNLPTTENSIGIYQYDFGIQHTVSGKLTRNIMNDFIIKHHVPIYSEFSDFIFSKSFVGHYH-YFVPIIFKSFPIPLNEMKAEIRKIAKELDGKAIFIHFDISKKKVQRFLEHLSIPENE--GFRVVESSEHLVNFKPENPLNLNGTYMLSFIRQVMDGTAEPELMASEPRENWHLEPIKHLTRKTYDQVVMDKTKNVFVIIYAPDCPYSREMLELLDKLGEMYKDDENVLLAKLDSSVDELPRIRVRSTPMMFLYLKDTNERIKFHGERTIENLKKFIESNGQ 1458
D K +E A S +D+ + A++ F + ++++ +++ G + +G T + + F+ + +P+ +EF+ F G + + + KS + + +++ A++ GKA+FI+ DI + +R LE + + + R + E +V +KPE ++ + F++ V+DG +P LM+ E +W EP+K L K +++V DKTKNV V YAP C + +++ + DKLGE YK+ EN+++AK+DS+ +E+ ++V+S P + + +++E I + G+RT+E KKF+ES G+
Sbjct: 166 DSAKSYEDAAFSKLEDIPCGMADSADIMAEFKV--DQDTVMLFKKTDGARIPYTGPFTADEVAKFVKNNKLPLINEFTQETAGDIFGGDVKKHLLVFLKKSDEAQFSNIMDQLKAPAEQFKGKALFIYVDIGVEDNERILEFFGLKKEDCPAVRFIALDEDMVKYKPEF-TDITADNLAQFVQSVLDGKLKPHLMSQEVPADWDKEPVKVLVGKNFNEVARDKTKNVLVEFYAPWCGHCKQLAPIWDKLGEEYKNHENIVIAKMDSTANEVEDVKVQSFPTIKFFPANSDEIIDYEGDRTLEGFKKFLESGGK 475 HSP 2 Score: 76.6406 bits (187), Expect = 2.752e-52 Identity = 46/159 (28.93%), Postives = 82/159 (51.57%), Query Frame = 2
Query: 44 LITFALFSLSLSFYCNGDEIPIIEEDDHCLLLTDQNWDYAHKIYEYILVFFYKPDCDQCTLSDEIFVYAAKHAKETKHTVKFAFVDAANEKTIATLEQIETVPVMKFYRNKTGVQYLRTQGKEEVIQWLTDRVNYELKPISTLDDGKNTLLNNLLVVFG 520
+ ALFSL ++ DE I E++ L+LT++N+D A + +YILV FY P C C + AA+ KE +K A VDA E +A ++ P +KF++ +T ++Y + + +I WL ++ + + ++D + + + + V G
Sbjct: 3 MFKLALFSL-VACVAFADEA--ITEEEGVLVLTEKNFDSALQANKYILVEFYAPWCGHCKALAPEYAKAAQQLKEKNSEIKLAKVDATVEGKLAEKYGVQGYPTIKFFKEQTPIEYSGGRTADTIISWLEKKLGPPTQRLDSVDAAQKFINDKEITVIG 158
BLAST of Protein disulfide-isomerase vs. TrEMBL
Match: A0A0K0FC49 (Protein disulfide-isomerase OS=Strongyloides venezuelensis OX=75913 PE=3 SV=1) HSP 1 Score: 157.532 bits (397), Expect = 8.777e-52 Identity = 94/319 (29.47%), Postives = 169/319 (52.98%), Query Frame = 1
Query: 532 DDIKDFEIVASMHDDVEFRLLKDAELCQRFNLPTTENSIGIYQYDFGIQHTVSGKLTRNIMNDFIIKHHVPIYSEFS----DFIFSKSFVGHYHYFVPIIFKSFPIPLNEMKAEIRKIAKELDGKAIFIHFDISKKKVQRFLEHLSIPENE--GFRVVESSEHLVNFKPENPLNLNGTYMLSFIRQVMDGTAEPELMASEPRENWHLEPIKHLTRKTYDQVVMDKTKNVFVIIYAPDCPYSREMLELLDKLGEMYKDDENVLLAKLDSSVDELPRIRVRSTPMMFLYLKDTNERIKFHGERTIENLKKFIESNGQDGNE 1470
D+ K F VA DDV F + +A+ + L E + + ++D G ++ GK+ + FI + + + +EFS IF H F+P + F +++ E + AKE GK +F+H + R +E + +E R++ E +V FKP+ ++ + F ++ +DG +P LM+ E E+W +P+K L K + +V D K+V V YAP C + +++ + DKLGE +KD+E+V++AK+DS+++E+ +++ S P + + +++ I ++G+RT+E FIES G+ G E
Sbjct: 169 DEAKAFLEVAGSMDDVPFAITSEADAAKAVEL-KDEGVVLLKKFDEG-RNEYEGKVEEAKLKTFIQANRLALVNEFSQETASVIFGGEIKSHNLLFIPKGSEDF----DKVYGEFQTAAKEYKGKLLFVHINTDDADNARIMEFFGLKNDELPAIRLISLEEDMVKFKPDF-TDITAENIKQFTQKYLDGKLKPHLMSEEVPEDWDAKPVKVLVGKNFAEVAKDPKKSVLVKFYAPWCGHCKQLAPIWDKLGEAFKDNEDVVIAKMDSTLNEVEDVKINSFPTIKFFPAGSDKVIDYNGDRTLEAFTSFIESGGKKGGE 480 HSP 2 Score: 77.411 bits (189), Expect = 8.777e-52 Identity = 40/136 (29.41%), Postives = 70/136 (51.47%), Query Frame = 2
Query: 113 EEDDHCLLLTDQNWDYAHKIYEYILVFFYKPDCDQCTLSDEIFVYAAKHAKETKHTVKFAFVDAANEKTIATLEQIETVPVMKFYRNKTGVQYLRTQGKEEVIQWLTDRVNYELKPISTLDDGKNTLLNNLLVVFG 520
EE++ ++LT +N+D +E++LV FY P C C + AA+ K+ TV+ A +DA +AT ++ P +KF++N +Y + ++ WL + KP++T DD K+ + +VV G
Sbjct: 26 EEEEDVIVLTKENFDGVIADHEFVLVEFYAPWCGHCKALAPNYAKAAQQLKKEGATVRLAKLDATVHSDVATKFEVRGYPTIKFFKNGKPTEYTGGRDATSIVSWLKKKTGPAAKPLTTADDAKDFQDSADVVVVG 161
BLAST of Protein disulfide-isomerase vs. Ensembl Cavefish
Match: p4hb (prolyl 4-hydroxylase subunit beta [Source:NCBI gene;Acc:103023413]) HSP 1 Score: 160.999 bits (406), Expect = 1.057e-49 Identity = 100/320 (31.25%), Postives = 172/320 (53.75%), Query Frame = 1
Query: 532 DDIKDFEIVASMHDDVEFRLLKDAELCQRFNLPTTENSIGIYQ-YDFGIQHTVSGKLTRNIMNDFIIKHHVPIYSEFSDFIFSKSFVG----HYHYFVPIIFKSFPIPLNEMKAEIRKIAKELDGKAIFIHFDISKKKVQRFLEHLSIPENE--GFRVVESSEHLVNFKPENPLNLNGTYMLSFIRQVMDGTAEPELMASEPRENWHLEPIKHLTRKTYDQVVMDKTKNVFVIIYAPDCPYSREMLELLDKLGEMYKDDENVLLAKLDSSVDELPRIRVRSTPMM-FLYLKDTNERIKFHGERTIENLKKFIESNGQDGN 1467
D K F A DD+ F + D + +F + TE+S+ +++ +D G ++T G+L++ + FI + +P+ EF++ K F G H FVP K F ++ RK A+ GK +FI D QR LE + + E R++ + + +KPE + +++F +G +P LM+ + E+W P+K L K +++VV D TKNVFV YAP C + +++ + D+LGE YKD ++V++AK+DS+ +E+ ++V S P + F + ++ I + GERT++ KF+ES G++G
Sbjct: 165 DGAKAFIKAAEAVDDIPFGISSDDAVFSKFEV--TEDSVVLFKKFDEG-RNTFDGELSKEGLLSFIKANQLPLVIEFTEQTAPKIFGGEIKSHILLFVPKASKDFQDKMDNF----RKAAEGFKGKILFIFIDSDVDDNQRILEFFGLKKEECPALRLITLEDEMTKYKPEAS-EITAENIITFCTAFTEGKLKPHLMSQDIPEDWDKTPVKTLVGKNFEEVVFDPTKNVFVEFYAPWCGHCKQLAPIWDQLGEKYKDSKDVVIAKMDSTANEIEAVKVHSFPTLKFFPAGEEHKIIDYSGERTLDGFTKFLESGGKEGG 476 HSP 2 Score: 56.225 bits (134), Expect = 1.057e-49 Identity = 32/140 (22.86%), Postives = 62/140 (44.29%), Query Frame = 2
Query: 110 IEEDDHCLLLTDQNWDYAHKIYEYILVFFYKPDCDQCTLSDEIFVYAAKHAKETKHTVKFAFVDAANEKTIATLEQIETVPVMKFYRN---KTGVQYLRTQGKEEVIQWLTDRVNYELKPISTLDDGKNTLLNNLLVVFG 520
+ E++ L+L N++ A K + ILV FY P C C + AA K ++ VDA E +A + P +KF++ + +Y + ++++ WL R ++ + ++ + +N + V G
Sbjct: 18 LSEEEDVLVLNKSNFEEALKAHPNILVEFYAPWCGHCKALAPEYAKAAGMLKAEGSDIRLGKVDATEEADLAQEFGVRGYPTIKFFKGGEKSSPKEYSAGRQADDIVNWLKKRTGPAAAALTEVTQAESLIADNEVAVIG 157
BLAST of Protein disulfide-isomerase vs. Ensembl Cavefish
Match: pdia2 (protein disulfide isomerase family A, member 2 [Source:ZFIN;Acc:ZDB-GENE-040426-705]) HSP 1 Score: 119.783 bits (299), Expect = 2.212e-37 Identity = 90/330 (27.27%), Postives = 171/330 (51.82%), Query Frame = 1
Query: 514 VRMHFVDDI-----KDFEIVASMHDDVEFRLLKDAELCQRFNLPTTENSIGIYQ-YD---FGIQHTVSGKLTRNIMNDFIIKHHVPIYSEFS----DFIFSKSFVGHYHYFVPIIFKSFPIPLNEMKAEIRKIAKELDGKAIFIHFDISKKKVQRFLEHLSIPENEG--FRVVESSEHLVNFKPENPLNLNGTYMLSFIRQVMDGTAEPELMASEPRENWHLEPIKHLTRKTYDQVVMDKTKNVFVIIYAPDCPYSREMLELLDKLGEMYKDDENVLLAKLDSSVDELPRIRVRSTPMMFLYLKDTNERI-KFHGERTIENLKKFIESNG 1455
V + F DD+ K F VA + F + EL +++N+ ++S+ +++ +D I GKL ++ + FI + + + FS D IFS H F+ +S N + + R A E GK +FI D++++ V +++ I ++ R + +++ + + E +N + +F + V+DG +P LM+ E E+W+ P+K L K ++ + D++KNVFV YAP C + +E+ + +KLGE YKD E++++A +DS+ +E+ + V+ P + + T +I ++G+R +E KF+++ G
Sbjct: 185 VVVGFFDDLNGEEAKVFYSVAVDMVSLNFGITSSPELFKKYNV--NKDSVVLFKKFDDKRADISLPEDGKLDKDNLVTFIQNNSLELIITFSEENADKIFSSKVHNHILLFINTTIESH----NALLDDYRAAAVEFKGKVLFIKIDVNEE-VSHVMKYFGISASDTPVLRFI-NTDTVKKYAMEEE-TINKDTLKTFCQGVLDGKIKPHLMSQEIPEDWNKNPVKVLVGKNFEHIAFDESKNVFVEFYAPWCGHCKELAPVWEKLGEKYKDHEDIIIANMDSTANEVEGVTVQGFPTLKFFPAGTERKIVDYNGKRDLETFSKFLDNGG 505 HSP 2 Score: 56.6102 bits (135), Expect = 2.212e-37 Identity = 35/133 (26.32%), Postives = 61/133 (45.86%), Query Frame = 2
Query: 131 LLLTDQNWDYAHKIYEYILVFFYKPDCDQCTLSDEIFVYAAKHAKETKHTVKFAFVDAANEKTIATLEQIETVPVMKFY---RNKTGVQYLRTQGKEEVIQWLTDRVNYELKPISTLDDGKNTLLNNLLVVFG 520
L+L N+D A +Y+LV FY P C C + + ++ A+ K ++ A VDA EK +A I+ P +KF+ R + + + ++ + WL +V + D + L + +VV G
Sbjct: 56 LVLHSVNFDRALSESKYLLVEFYAPWCSHCRMLEPVYSQVARQLKNESSPIRLAKVDATEEKELAEEFGIDGFPTLKFFKEGRRQNATDFTGKRTEKGIKLWLQRQVEPPATVLKNTKDAQELLDAHDVVVVG 188
BLAST of Protein disulfide-isomerase vs. Ensembl Cavefish
Match: zgc:136472 (protein disulfide-isomerase-like [Source:NCBI gene;Acc:103036532]) HSP 1 Score: 78.1814 bits (191), Expect = 9.884e-25 Identity = 70/316 (22.15%), Postives = 150/316 (47.47%), Query Frame = 1
Query: 538 IKDFEIVASMHDDVEFRLLKDAELCQRFNLPTTENSIGIYQYDFGIQH-TVSGKLTRNIMNDFIIKHHVPIYSEF----SDFIFSKSFVGHYHYFVPIIFKSFPIPLNEMKAEIRKIAKELDGKAIFIHFDISKKKVQRFLEHLSIPENEG--FRVVESSEHLVNFKPENPLNLNGTYMLS-FIRQVMDGTAEPELMASEPRENWHLEPIKHLTRKTYDQVVMDKTKNVFVIIYAPDCPYSREMLELLDKLGEMYKDDENVLLAKLDSSVDELPRIRVRSTPMMFLYLKDTNER-IKFHGERTIENLKKFIESNGQ 1458
+K F VA+ D+ F + + ++ ++ TENS+ + + +H ++ + ++ + FI H +P+ +E+ S I S H F+ K F K+ AKE GK +F+ D + + R +E+ + + + R+V ++ +F+ + P +L + FI + G A+ +L + + W +P+K L +++V + KNV ++ Y+P SR + L + L E + D E+V++A++D + +++ + P + ++ ER + + GE +E + +F+ + +
Sbjct: 175 VKVFYEVAADVPDLPFGVTGNEQVFSKYG--RTENSVLLLRKSKMAEHFEMTSETVKDDVILFIRIHEMPLVTEYNGKTSSKILSSVVQNHLILFMDKAGKGFKQTYRAFKS----TAKEFRGKVLFVLIDSGEPRNGRIMEYFRVRKEDAPLVRMVNLTD---SFQYQLPSDLMDIQTFTDFIESYLQGKAKLKLQSEPVPDGWDKQPVKELVGMNFERVAFNHEKNVLILFYSPWSSDSRALFPLWEDLAEHFSDSEDVVVARIDITANDVNIRMMDRYPCIKVFPAVYAERVVSYSGEAKLEPIVEFVNAESE 481 HSP 2 Score: 55.0694 bits (131), Expect = 9.884e-25 Identity = 40/142 (28.17%), Postives = 63/142 (44.37%), Query Frame = 2
Query: 110 IEEDDHCLLLTDQNWDYAHKIYEYILVFFYKPDCDQCTLSDEIFVYAAKHAKETKHTVKFAFVDAANEKTIATLEQIETVPVMKFYRNKTGVQYLRT-----QGKEEVIQWLTDRVNYELKPISTLDDGKNTLLNNLLVVFG 520
I+ED L+LT+ N++ A K++ +LV FY P + S F AA KE VK +D + +K +A + TVP ++ Y +G +Y + +I WL R I L + + LV+ G
Sbjct: 26 IQEDKDVLVLTESNFNRALKLHSQLLVHFYAPLSGESLGSILEFAQAASELKEANSDVKLGGLDVSKQKDLAKTLNVTTVPSVRLYL--SGDKYNPVYCPVLKSSASIISWLKRRKGPSADLIKDLSQLEKFTAEDDLVILG 165
BLAST of Protein disulfide-isomerase vs. Ensembl Cavefish
Match: zgc:136472 (protein disulfide-isomerase-like [Source:NCBI gene;Acc:103036532]) HSP 1 Score: 78.1814 bits (191), Expect = 1.444e-24 Identity = 68/315 (21.59%), Postives = 147/315 (46.67%), Query Frame = 1
Query: 538 IKDFEIVASMHDDVEFRLLKDAELCQRFNLPTTENSIGIYQYDFGIQH-TVSGKLTRNIMNDFIIKHHVPIYSEF----SDFIFSKSFVGHYHYFVPIIFKSFPIPLNEMKAEIRKIAKELDGKAIFIHFDISKKKVQRFLEHLSIPENEG--FRVVESSEHLVNFKPENPLNLNGTYMLSFIRQVMDGTAEPELMASEPRENWHLEPIKHLTRKTYDQVVMDKTKNVFVIIYAPDCPYSREMLELLDKLGEMYKDDENVLLAKLDSSVDELPRIRVRSTPMMFLYLKDTNER-IKFHGERTIENLKKFIESNGQ 1458
+K F VA+ D+ F + + ++ ++ TENS+ + + +H ++ + ++ + FI H +P+ +E+ S I S H F+ K F K+ AKE GK +F+ D + + R +E+ + + + R+V ++ P + +++ FI + G A+ +L + + W +P+K L +++V + KNV ++ Y+P SR + L + L E + D E+V++A++D + +++ + P + ++ ER + + GE +E + +F+ + +
Sbjct: 178 VKVFYEVAADVPDLPFGVTGNEQVFSKYG--RTENSVLLLRKSKMAEHFEMTSETVKDDVILFIRIHEMPLVTEYNGKTSSKILSSVVQNHLILFMDKAGKGFKQTYRAFKS----TAKEFRGKVLFVLIDSGEPRNGRIMEYFRVRKEDAPLVRMVNLTDSFQYQLPSDLMDIQT--FTDFIESYLQGKAKLKLQSEPVPDGWDKQPVKELVGMNFERVAFNHEKNVLILFYSPWSSDSRALFPLWEDLAEHFSDSEDVVVARIDITANDVNIRMMDRYPCIKVFPAVYAERVVSYSGEAKLEPIVEFVNAESE 484 HSP 2 Score: 55.0694 bits (131), Expect = 1.444e-24 Identity = 40/142 (28.17%), Postives = 63/142 (44.37%), Query Frame = 2
Query: 110 IEEDDHCLLLTDQNWDYAHKIYEYILVFFYKPDCDQCTLSDEIFVYAAKHAKETKHTVKFAFVDAANEKTIATLEQIETVPVMKFYRNKTGVQYLRT-----QGKEEVIQWLTDRVNYELKPISTLDDGKNTLLNNLLVVFG 520
I+ED L+LT+ N++ A K++ +LV FY P + S F AA KE VK +D + +K +A + TVP ++ Y +G +Y + +I WL R I L + + LV+ G
Sbjct: 29 IQEDKDVLVLTESNFNRALKLHSQLLVHFYAPLSGESLGSILEFAQAASELKEANSDVKLGGLDVSKQKDLAKTLNVTTVPSVRLYL--SGDKYNPVYCPVLKSSASIISWLKRRKGPSADLIKDLSQLEKFTAEDDLVILG 168
BLAST of Protein disulfide-isomerase vs. Ensembl Cavefish
Match: zgc:136472 (protein disulfide-isomerase-like [Source:NCBI gene;Acc:103036532]) HSP 1 Score: 75.485 bits (184), Expect = 5.613e-24 Identity = 70/312 (22.44%), Postives = 147/312 (47.12%), Query Frame = 1
Query: 538 IKDFEIVASMHDDVEFRLLKDAELCQRFNLPTTENSIGIYQYDFGIQH-TVSGKLTRNIMNDFIIKHHVPIYSEF----SDFIFSKSFVGHYHYFVPIIFKSFPIPLNEMKAEIRKIAKELDGKAIFIHFDISKKKVQRFLEHLSIPENEG--FRVVESSEHLVNFKPENPLNLNGTYMLS-FIRQVMDGTAEPELMASEPRENWHLEPIKHLTRKTYDQVVMDKTKNVFVIIYAPDCPYSREMLELLDKLGEMYKDDENVLLAKLDSSVDELPRIRVRSTPMMFLYLKDTNERIK--FHGERTIENLKKFI 1443
+K F VA+ D+ F + + ++ ++ TENS+ + + +H ++ + ++ + FI H +P+ +E+ S I S H F+ K F + + AKE GK +F+ D + + R +E+ + + + R+V ++ +F+ + P +L + FI + G A+ +L + + W +P+K L +++V + KNV ++ Y+P SR + L + L E + D E+V++A++D + +++ + P + ++ ER++ + + T LK FI
Sbjct: 178 VKVFYEVAADVPDLPFGVTGNEQVFSKYG--RTENSVLLLRKSKMAEHFEMTSETVKDDVILFIRIHEMPLVTEYNGKTSSKILSSVVQNHLILFMDKAGKGF----KQTYRAFKSTAKEFRGKVLFVLIDSGEPRNGRIMEYFRVRKEDAPLVRMVNLTD---SFQYQLPSDLMDIQTFTDFIESYLQGKAKLKLQSEPVPDGWDKQPVKELVGMNFERVAFNHEKNVLILFYSPWSSDSRALFPLWEDLAEHFSDSEDVVVARIDITANDVNIRMMDRYPCIKVFPAVYAERVRSIWSSKLTFTYLKLFI 480 HSP 2 Score: 55.4546 bits (132), Expect = 5.613e-24 Identity = 40/142 (28.17%), Postives = 63/142 (44.37%), Query Frame = 2
Query: 110 IEEDDHCLLLTDQNWDYAHKIYEYILVFFYKPDCDQCTLSDEIFVYAAKHAKETKHTVKFAFVDAANEKTIATLEQIETVPVMKFYRNKTGVQYLRT-----QGKEEVIQWLTDRVNYELKPISTLDDGKNTLLNNLLVVFG 520
I+ED L+LT+ N++ A K++ +LV FY P + S F AA KE VK +D + +K +A + TVP ++ Y +G +Y + +I WL R I L + + LV+ G
Sbjct: 29 IQEDKDVLVLTESNFNRALKLHSQLLVHFYAPLSGESLGSILEFAQAASELKEANSDVKLGGLDVSKQKDLAKTLNVTTVPSVRLYL--SGDKYNPVYCPVLKSSASIISWLKRRKGPSADLIKDLSQLEKFTAEDDLVILG 168
BLAST of Protein disulfide-isomerase vs. Ensembl Sea Lamprey
Match: ENSPMAT00000002052.1 (pep scaffold:Pmarinus_7.0:GL480798:2613:20969:-1 gene:ENSPMAG00000001848.1 transcript:ENSPMAT00000002052.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 78.9518 bits (193), Expect = 4.063e-16 Identity = 64/298 (21.48%), Postives = 136/298 (45.64%), Query Frame = 1
Query: 535 DIKDFEIVASMHDDVEFRLLKDAELCQRFNLPTTENSIGIYQYDFGIQHTVSGKLT--RNIMNDFIIKHHVPIYSEFSDFIFSKSFVG----HYHYFVPIIFKSFPIPLNEMKAEIRKIAKELDGKAIFIHFDISKKKVQRFLEHLSIPENE---GFRVVESSEHLVNFKPENPLNLNGTYMLSFIRQVMDGTAEPELMASEPRENWHLEPIKHLTRKTYDQVVMDKTKNVFVIIYAPDCPYSREMLELLDKLGEMYKDDENVLLAKLDSSVDELPRIRVRSTPMMFLYLKDTNERIK 1401
D+K F +A +D+V F + E+ ++ + +T++ + ++D G + L I + + H + F F G H F + FP E+ + + A GK +F+ + + + L+ + + R+V+ ++ +V P + + SF + +D +P + E ++W+ P+K L K +D+ V D+TKNVFV YA C + +++ + ++LG YKD +N+++AK+D+ +E+ + + P + + ++++
Sbjct: 116 DLKTFLEIADTYDEVPFGVTSSEEVFAKYGV-STDSIVLFKKFDEGQKSFTPIDLNFRHGIKSHTAVVHGCECLCGCTVQTFPLLFSGLVNVHILLFANASSEGFP----ELFEQFKAAAPPFRGKILFVLLNSAVPENDNVLDLFELTDGARLPAIRLVKVNKDMVKHVPSFS-DFTTANITSFCQDYLDEHNKPFSKSQEIPKDWNKRPVKVLVGKNFDEFVFDETKNVFVEFYASWCDHCKKLAPVWEQLGVQYKDHDNIVIAKMDAEKNEVAAVHIPGYPKIKYFPAGPGKKVR 407
BLAST of Protein disulfide-isomerase vs. Ensembl Sea Lamprey
Match: pdia4 (protein disulfide isomerase family A, member 4 [Source:ZFIN;Acc:ZDB-GENE-030131-5493]) HSP 1 Score: 69.707 bits (169), Expect = 8.373e-13 Identity = 36/123 (29.27%), Postives = 72/123 (58.54%), Query Frame = 1
Query: 1099 LMASEPRENWHLEPIKHLTRKTYDQVVMDKTKNVFVIIYAPDCPYSREMLELLDKLGEMYKDDENVLLAKLDSSVDELP--RIRVRSTPMMFLYLKDTNER-IKFH-GERTIENLKKFIESNG 1455
++ S+P + P+K + +T++Q+V+D +K+V + YAP C + + + + LG+ YK + +++AK+D++V+++P + P ++ +R IKF G R +E+L KFIE +
Sbjct: 508 VVKSQPLPKSNKGPVKVVVGRTFEQMVLDNSKDVLIEFYAPWCGHCKSLEPIYKDLGKKYKGHKGLVIAKMDATVNDIPHDSYKAEGFPTIYFSPSGAKDRPIKFADGSRDLESLSKFIEKHA 630
BLAST of Protein disulfide-isomerase vs. Ensembl Sea Lamprey
Match: pdia3 (protein disulfide isomerase family A, member 3 [Source:ZFIN;Acc:ZDB-GENE-031002-9]) HSP 1 Score: 61.2326 bits (147), Expect = 2.874e-10 Identity = 39/142 (27.46%), Postives = 79/142 (55.63%), Query Frame = 1
Query: 1039 NGTYMLSFIRQVMDGTAEPELMASEPRENWHLEPIKHLTRKTYDQVVMDKTKNVFVIIYAPDCPYSREM----LELLDKLGEMYKDDENVLLAKLDSSVDELP-RIRVRSTPMMFLY-LKDTNERIKFHGERTIENLKKFIE 1446
+G + +F++ DG + L SEP + P+K + + +D++V D++K+V + YAP C + + + LEL DKL K+D N+L+AK+D++ +++P + VR P ++ + + K+ G R + + +++
Sbjct: 341 DGKSLENFLQDYFDGKLKKHLK-SEPIPEDNDGPVKVVVAEIFDELVNDESKDVLIEFYAPWCGHCKNLEPKYLELADKL----KNDPNILIAKMDATANDVPAQYDVRGFPTIYFSPMGSKDSPKKYEGGREVSDFISYLK 477
BLAST of Protein disulfide-isomerase vs. Ensembl Yeast
Match: EUG1 (Protein disulfide isomerase of the endoplasmic reticulum lumen; EUG1 has a paralog, PDI1, that arose from the whole genome duplication; function overlaps with that of Pdi1p; may interact with nascent polypeptides in the ER [Source:SGD;Acc:S000002926]) HSP 1 Score: 48.1358 bits (113), Expect = 2.181e-6 Identity = 51/185 (27.57%), Postives = 94/185 (50.81%), Query Frame = 1
Query: 1015 KPENPLNLNGTYMLSFIRQVMDGTAEPELMASE-PRENWHLEPIKHLTRKTYDQVVMDKTKNVFVIIYAPDCPYSREMLELLDKLGEMYKDDENV----LLAKLDSSVDELPRIRVRSTPMMFLYLKDTNER-IKFHGERTIENLKKFIESNGQDGNEQQFLEIDHLQHARLTE---NGLVHEEL 1542
K E P L+ ++ ++ +GTA+P + + E P+E + + KT+D +V D K+V V YA C +S+ + +++ + DE+V L+A++DS +++ V P + LY N + I F+ R +E++ +FI+ +G + Q + D L A+ +E VH+EL
Sbjct: 336 KLEKPQPLDRDMIVQLVKDYREGTAKPIVKSEEIPKE--QKSNVYKIVGKTHDDIVHDDDKDVLVKYYATWCIHSKRFAPIYEEIANVLASDESVRDKILIAEVDSGANDILSFPVTGYPTIALYPAGNNSKPIIFNKIRNLEDVFEFIKESGTHHIDGQAI-YDKLHQAKDSEVSTEDTVHDEL 517
BLAST of Protein disulfide-isomerase vs. Ensembl Nematostella
Match: EDO36830 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SHH5]) HSP 1 Score: 139.428 bits (350), Expect = 9.286e-49 Identity = 86/316 (27.22%), Postives = 162/316 (51.27%), Query Frame = 1
Query: 532 DDIKDFEIVASMHDDVEFRLLKDAELCQRFNLPTTENSIGIYQYDFGIQHTVSGKLTRNIMNDFIIKHHVPIYSEFSDFIFSKSFVGHYHYFVPIIFKSFPIPLNEMKAEIRKIAKELDGKAIFIHFDISKKKVQRFLEHLSIPENE--GFRVVE-SSEHLVNFKPENPLNLNGTYMLSFIRQVMDGTAEPELMASEPRENWHLEPIKHLTRKTYDQVVMDKTKNVFVIIYAPDCPYSREMLELLDKLGEMYKDDENVLLAKLDSSVDELPRIRVRSTPMMFLYLKDTNERIKFHGERTIENLKKFIESNGQDGNE 1470
D K F A DDVEF ++ D + + + + ++D G ++ G+ + F+ + +P+ +EFSD K F G + + + AK+ GK +F++ + + QR +E I +E R++ + + + +KP + + F++ +D +P L+++E E+W +P+K L K +D+V +K KNVFV YAP C + +++ + D+LGE YKD ++++AK+DS+ +E+ ++V S P + + K+ E + ++G RT+++ KF+ES G+ GNE
Sbjct: 163 DAAKAFLSAADGIDDVEFGIVSDKAIASEHKV-EGDKIVLFKKFDEG-RNDYDGEYDFEKIQQFVKANQLPLVTEFSDETAPKIFGGDVKHHILLFTNKTSDGFKATHEAFTGGAKDFKGKVLFVYVNTEVEDNQRIVEFFGIQSSELPTIRLINLADDDMTKYKP-TAAEITSENVKEFVQAFLDKKLKPHLLSAEIPEDWDSKPVKVLCGKNFDEVARNKDKNVFVEFYAPWCGHCKQLAPIWDQLGEKYKDHADIVVAKMDSTANEVEGVKVHSFPTIKYFPKE-GEAVDYNGGRTLDDFVKFLESGGKAGNE 474 HSP 2 Score: 73.1738 bits (178), Expect = 9.286e-49 Identity = 39/135 (28.89%), Postives = 68/135 (50.37%), Query Frame = 2
Query: 110 IEEDDHCLLLTDQNWDYAHKIYEYILVFFYKPDCDQCTLSDEIFVYAAKHAKETKHTVKFAFVDAANEKTIATLEQIETVPVMKFYRNKTGVQYLRTQGKEEVIQWLTDRVNYELKPISTLDDGKNTLLNNLLVV 514
I+E++ L+LT++N+D A +++LV FY P C C + AA K K +K A VDA E + Q++ P +KF+++ +Y + E++ WL + K ++T D K+ + + VV
Sbjct: 20 IKEEEDVLVLTEKNFDEAVAANKHVLVEFYAPWCGHCKALAPEYAKAAGQLKSEKSEIKLAKVDATAETKLGEKFQVQGYPTIKFFKDGKPSEYAGGRTAPEIVSWLNKKTGPPAKDLATADAMKDFITKEVAVV 154
BLAST of Protein disulfide-isomerase vs. Ensembl Nematostella
Match: EDO33843 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SR22]) HSP 1 Score: 77.7962 bits (190), Expect = 4.889e-17 Identity = 41/130 (31.54%), Postives = 76/130 (58.46%), Query Frame = 1
Query: 1063 IRQVMDGTAEPELMASEPRENWHLEPIKHLTRKTYDQVVMDKTKNVFVIIYAPDCPYSREMLELLDKLGEMYKDDENVLLAKLDSSVDELPRI-RVRSTPMM-FLYLKDTNERIKFHGERTIENLKKFIE 1446
I + G +P ++ S+P + EP+ + KT+D++V D K+V + YAP C + + + KLG+ +++D+N+++AK+D++ +++P V P + F KD IKF G R +++L KF+E
Sbjct: 4 ISALFSGNLKP-IVKSQPVPKSNKEPVTVVVGKTFDEIVNDPKKDVLIEFYAPWCGHCKALEPTFKKLGKHFRNDKNIVIAKIDATANDVPSTYAVEGFPTIYFATSKDKKNPIKFDGGRELKDLIKFVE 132
BLAST of Protein disulfide-isomerase vs. Ensembl Nematostella
Match: EDO32930 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7STM8]) HSP 1 Score: 77.411 bits (189), Expect = 4.349e-15 Identity = 41/137 (29.93%), Postives = 78/137 (56.93%), Query Frame = 1
Query: 1051 MLSFIRQVMDGTAEPELMASEPRENWHLEPIKHLTRKTYDQVVMDKTKNVFVIIYAPDCPYSREMLELLDKLGEMYKDDENVLLAKLDSSVDELPRI-RVRSTPMM-FLYLKDTNERIKFHGERTIENLKKFIESNG 1455
+ F+ + G +P ++ S+P + EP+ + KT+D++V D K+V + YAP C + + + KLG+ +++D+N+++AK+D++ +++P V P + F KD IKF G R +++L KF+E
Sbjct: 498 LREFVEEFKAGNLKP-IIKSQPVPKSNKEPVTVVVGKTFDEIVNDPKKDVLIEFYAPWCGHCKALEPTFKKLGKHFRNDKNIVIAKIDATANDVPSTYAVEGFPTIYFATSKDKKNPIKFDGGRELKDLIKFVEEKA 633 HSP 2 Score: 53.1434 bits (126), Expect = 1.820e-7 Identity = 34/130 (26.15%), Postives = 61/130 (46.92%), Query Frame = 2
Query: 89 NGDEIPIIEEDDHCLLLTDQNWDYAHKIYEYILVFFYKPDCDQCTLSDEIFVYAAKHAKETKHTVKFAFVDAANEKTIATLEQIETVPVMKFYRNKTGVQYLRTQGKEEVIQWLTDR--VNYELKPISTL 472
+ D+ ++E+D L+L +N+D + ILV FY P C C + AAK K V FA +DA IA + P +K +R T +Y + + +++++ + N++ P++ L
Sbjct: 50 DADDSDEVKEEDDVLVLNSKNFDRVIEENNIILVEFYAPWCGHCKSLAPEYAKAAKKMKLNDPPVPFAKMDATVASDIAQRFDVSGYPTLKIFRKGTPYEYEGPREESGIVEYMKKQSDPNWKPPPVAAL 179
BLAST of Protein disulfide-isomerase vs. Ensembl Nematostella
Match: EDO31634 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SXD7]) HSP 1 Score: 58.9214 bits (141), Expect = 2.462e-9 Identity = 34/131 (25.95%), Postives = 69/131 (52.67%), Query Frame = 1
Query: 1060 FIRQVMDGTAEPELMASEPRENWHLEPIKHLTRKTYDQVVMDKTKNVFVIIYAPDCPYSREMLELLDKLGEMYKDDENVLLAKLDSSV-DELPRIRVRSTPMMFLYLKDTNERI-KFHGERTIENLKKFIE 1446
F+ G+ +P + SEP + P+K + + + ++V D TK+V + YAP C + + + ++LGE +D +++++AK+D++ D P V+ P ++ + E K+ G R + + FI+
Sbjct: 337 FLEDYFAGSLKPHI-KSEPLPESNDGPVKVVVGENFKEIVNDPTKDVLIEFYAPWCGHCKSLEPKYNELGEKLQDVKDIVIAKMDATANDAPPNFSVQGFPTIYWAPANNKENPEKYEGGREVSDFVDFIK 466
BLAST of Protein disulfide-isomerase vs. Ensembl Nematostella
Match: EDO47340 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RMG9]) HSP 1 Score: 53.5286 bits (127), Expect = 9.782e-8 Identity = 31/101 (30.69%), Postives = 54/101 (53.47%), Query Frame = 1
Query: 1150 LTRKTYDQVVMDKTKNVFVIIYAPDCPYSREMLELLDKLGEMYKDDENVLLAKLDSSVDE--LPRIRVRSTPMMFLYLKDTNERIKFHGERTIENLKKFIE 1446
LT+ +D+VV + K V YAP C + +++ ++LGE Y +V++AK+D+ D R V+ P + + K + +++G R I + KFIE
Sbjct: 27 LTKDNFDEVV-NGEKFALVEFYAPWCGHCKQLAPTYEQLGEAYTQSSDVIIAKVDADGDRDLGSRFDVKGFPTIKYFPKGSTTPEEYNGGRDINDFIKFIE 126
BLAST of Protein disulfide-isomerase vs. Ensembl Medaka
Match: p4hb (prolyl 4-hydroxylase subunit beta [Source:NCBI gene;Acc:101155742]) HSP 1 Score: 152.14 bits (383), Expect = 4.941e-48 Identity = 89/306 (29.08%), Postives = 163/306 (53.27%), Query Frame = 1
Query: 571 DDVEFRLLKDAELCQRFNLPTTENSIGIYQYDFGIQHTVSGKLTRNIMNDFIIKHHVPIYSEFSDFIFSKSFVG----HYHYFVPIIFKSFPIPLNEMKAEIRKIAKELDGKAIFIHFDISKKKVQRFLEHLSIPENE--GFRVVESSEHLVNFKPENPLNLNGTYMLSFIRQVMDGTAEPELMASEPRENWHLEPIKHLTRKTYDQVVMDKTKNVFVIIYAPDCPYSREMLELLDKLGEMYKDDENVLLAKLDSSVDELPRIRVRSTPMM-FLYLKDTNERIKFHGERTIENLKKFIESNGQDGN 1467
DDV F + + +F + + + + ++D G ++T G+LT++ + F+ + +P+ EF++ K F G H F+P F E + +K A G+ +FI D QR LE + + E R++ + + +KPE+ ++ +++F Q ++G +P LM+ + E+W P+K L K +++V D KNVF+ YAP C + +++ + DKLGE YKD ++++AK+DS+ +E+ ++V S P + F + + I ++GERT+E KF+ES G++G
Sbjct: 178 DDVPFAITSSDAVYSKFEV-SKDGVVLFKKFDEG-RNTFDGELTKDGLLAFVKANQLPLVIEFTEQTAPKIFGGDIKSHILMFLPKAASDF----QEKMEQFKKAAAGFKGQILFIFIDSDVDDNQRILEFFGLKKEECPAIRLITLEDEMTKYKPESK-DITAESIVAFCTQFVEGKLKPHLMSQDIPEDWDKNPVKVLVGKNFEEVAFDPKKNVFIEFYAPWCGHCKQLAPIWDKLGEKYKDSSDIVVAKMDSTANEIESVKVHSFPTLKFFPAGEERQVIDYNGERTLEGFTKFLESGGKEGG 476 HSP 2 Score: 59.6918 bits (143), Expect = 4.941e-48 Identity = 34/140 (24.29%), Postives = 65/140 (46.43%), Query Frame = 2
Query: 110 IEEDDHCLLLTDQNWDYAHKIYEYILVFFYKPDCDQCTLSDEIFVYAAKHAKETKHTVKFAFVDAANEKTIATLEQIETVPVMKFYRN---KTGVQYLRTQGKEEVIQWLTDRVNYELKPISTLDDGKNTLLNNLLVVFG 520
I E++ L+L N+D A + + ILV FY P C C + AA K ++ VDA E +A + P +KF++ ++ +Y + ++++ WL R + ++ + D ++ + +N + V G
Sbjct: 18 IAEEEDVLVLKKSNFDEALQAHPNILVEFYAPWCGHCKALAPEYAKAAGMLKAEGSQIRLGKVDATEETELAQEFGVRGYPTIKFFKGGDKESPKEYSAGRQADDMVNWLKKRTGPAVTSLTEVTDAESLIADNEVAVIG 157
BLAST of Protein disulfide-isomerase vs. Ensembl Medaka
Match: pdia2 (protein disulfide-isomerase [Source:NCBI gene;Acc:101164281]) HSP 1 Score: 119.783 bits (299), Expect = 6.215e-38 Identity = 87/311 (27.97%), Postives = 155/311 (49.84%), Query Frame = 1
Query: 547 FEIVASMHDDVEFRLLKDAELCQRFNLPTTENSIGIYQ-YDFG---IQHTVSGKLTRNIMNDFIIKHH----VPIYSEFSDFIFSKSFVGHYHYFVPIIFKSFPIPLNEMKAEIRKIAKELDGKAIFIHFDISKKKVQRFLEHLSIPENEGFRVVESSEHLVNFKPENPLNLNGTYMLSFIRQVMDGTAEPELMASEPRENWHLEPIKHLTRKTYDQVVMDKTKNVFVIIYAPDCPYSREMLELLDKLGEMYKDDENVLLAKLDSSVDELPRIRVRSTPMMFLYLKDTNERIKFHGERTIENLKKFIESNG 1455
F+ VA DVEF + E+ + + + T N + +++ +D G + + KL ++ + +FI ++ VP E SD IF+ H F+ +S L E K +A+E GK ++I D++ V L + + E + V ++N + + +V+D TAEP L + E E+W P+K L K ++ V MD TKNVFV YAP C + +E+ + ++LGE+Y D +++++AK+D++ +E+ + + P + + E I + G R +E L KF+++ G
Sbjct: 217 FKEVAFDLTDVEFAVTASPEVFKEYEV--TANKVVLFKKFDDGRADFELSEEDKLDKHNLTNFIKENSLELIVPFNQETSDKIFTSRVRLHCLLFINSTVESQMSLLEESKT----VAREFKGKVLYILIDMTTA-VSHVLNYFGVLEKDSPTV-----RMINMDTQKKFKI----------EVVDDTAEPYLRSEEIPEDWDKGPVKVLVAKNFETVAMDPTKNVFVEFYAPWCGHCKELAPIWEQLGEIYADHDDIIIAKMDATANEVESVAIDGFPTLKYFPAGDKEVISYTGNRDLETLSKFLDNGG 505 HSP 2 Score: 58.151 bits (139), Expect = 6.215e-38 Identity = 37/140 (26.43%), Postives = 65/140 (46.43%), Query Frame = 2
Query: 110 IEEDDHCLLLTDQNWDYAHKIYEYILVFFYKPDCDQCTLSDEIFVYAAKHAKETKHTVKFAFVDAANEKTIATLEQIETVPVMKFYRN---KTGVQYLRTQGKEEVIQWLTDRVNYELKPISTLDDGKNTLLNNLLVVFG 520
IEE+ ++L N+D A +++V FY P C C + I+ AA KE ++ A VDA EK +A +++ P +K + N K ++Y + ++QWL R +++ D + + + V G
Sbjct: 65 IEEEQGIMVLHINNFDRALSETRHLMVEFYAPWCGYCRRFEPIYAEAAGMLKEEGSEMRLAKVDAIEEKELAEEFNVDSFPTVKLFMNGDRKEPIEYTGKRTPSGIVQWLKRRSGPGAADLNSADSAAEFINTHNVSVVG 204
BLAST of Protein disulfide-isomerase vs. Ensembl Medaka
Match: pdia2 (protein disulfide-isomerase [Source:NCBI gene;Acc:101164281]) HSP 1 Score: 117.857 bits (294), Expect = 1.195e-37 Identity = 88/315 (27.94%), Postives = 157/315 (49.84%), Query Frame = 1
Query: 547 FEIVASMHDDVEFRLLKDAELCQRFNLPTTENSIGIYQ-YDFG---IQHTVSGKLTRNIMNDFIIKHH----VPIYSEFSDFIFSKSFVGHYHYFVPIIFKSFPIPLNEMKAEIRKIAKELDGKAIFIHFDISKKKVQRFLEHLSIPENEGFRVVESSEHLVNFKPENPLNLNGTYMLSFIRQ----VMDGTAEPELMASEPRENWHLEPIKHLTRKTYDQVVMDKTKNVFVIIYAPDCPYSREMLELLDKLGEMYKDDENVLLAKLDSSVDELPRIRVRSTPMMFLYLKDTNERIKFHGERTIENLKKFIESNG 1455
F+ VA DVEF + E+ + + + T N + +++ +D G + + KL ++ + +FI ++ VP E SD IF+ H F+ +S L E K +A+E GK ++I D++ V L + + E + V ++N + + + +RQ V+D TAEP L + E E+W P+K L K ++ V MD TKNVFV YAP C + +E+ + ++LGE+Y D +++++AK+D++ +E+ + + P + + E + G R +E L KF+++ G
Sbjct: 213 FKEVAFDLTDVEFAVTASPEVFKEYEV--TANKVVLFKKFDDGRADFELSEEDKLDKHNLTNFIKENSLELIVPFNQETSDKIFTSRVRLHCLLFINSTVESQMSLLEESKT----VAREFKGKVLYILIDMTTA-VSHVLNYFGVLEKDSPTV-----RMINMDTQKKFKIASEMTIDSLRQLSQEVVDDTAEPYLRSEEIPEDWDKGPVKVLVAKNFETVAMDPTKNVFVEFYAPWCGHCKELAPIWEQLGEIYADHDDIIIAKMDATANEVESVAIDGFPTLKYFPAGDKEV--YTGNRDLETLSKFLDNGG 513 HSP 2 Score: 58.9214 bits (141), Expect = 1.195e-37 Identity = 37/140 (26.43%), Postives = 65/140 (46.43%), Query Frame = 2
Query: 110 IEEDDHCLLLTDQNWDYAHKIYEYILVFFYKPDCDQCTLSDEIFVYAAKHAKETKHTVKFAFVDAANEKTIATLEQIETVPVMKFYRN---KTGVQYLRTQGKEEVIQWLTDRVNYELKPISTLDDGKNTLLNNLLVVFG 520
IEE+ ++L N+D A +++V FY P C C + I+ AA KE ++ A VDA EK +A +++ P +K + N K ++Y + ++QWL R +++ D + + + V G
Sbjct: 61 IEEEQGIMVLHINNFDRALSETRHLMVEFYAPWCGYCRRFEPIYAEAAGMLKEEGSEMRLAKVDAIEEKELAEEFNVDSFPTVKLFMNGDRKEPIEYTGKRTPSGIVQWLKRRSGPGAADLNSADSAAEFINTHNVSVVG 200
BLAST of Protein disulfide-isomerase vs. Ensembl Medaka
Match: pdia2 (protein disulfide-isomerase [Source:NCBI gene;Acc:101164281]) HSP 1 Score: 124.79 bits (312), Expect = 1.663e-30 Identity = 89/315 (28.25%), Postives = 158/315 (50.16%), Query Frame = 1
Query: 547 FEIVASMHDDVEFRLLKDAELCQRFNLPTTENSIGIYQ-YDFG---IQHTVSGKLTRNIMNDFIIKHH----VPIYSEFSDFIFSKSFVGHYHYFVPIIFKSFPIPLNEMKAEIRKIAKELDGKAIFIHFDISKKKVQRFLEHLSIPENEGFRVVESSEHLVNFKPENPLNLNGTYMLSFIRQ----VMDGTAEPELMASEPRENWHLEPIKHLTRKTYDQVVMDKTKNVFVIIYAPDCPYSREMLELLDKLGEMYKDDENVLLAKLDSSVDELPRIRVRSTPMMFLYLKDTNERIKFHGERTIENLKKFIESNG 1455
F+ VA DVEF + E+ + + + T N + +++ +D G + + KL ++ + +FI ++ VP E SD IF+ H F+ +S L E K +A+E GK ++I D++ V L + + E + V ++N + + + +RQ V+D TAEP L + E E+W P+K L K ++ V MD TKNVFV YAP C + +E+ + ++LGE+Y D +++++AK+D++ +E+ + + P + + E I + G R +E L KF+++ G
Sbjct: 104 FKEVAFDLTDVEFAVTASPEVFKEYEV--TANKVVLFKKFDDGRADFELSEEDKLDKHNLTNFIKENSLELIVPFNQETSDKIFTSRVRLHCLLFINSTVESQMSLLEESKT----VAREFKGKVLYILIDMTTA-VSHVLNYFGVLEKDSPTV-----RMINMDTQKKFKIASEMTIDSLRQLSQEVVDDTAEPYLRSEEIPEDWDKGPVKVLVAKNFETVAMDPTKNVFVEFYAPWCGHCKELAPIWEQLGEIYADHDDIIIAKMDATANEVESVAIDGFPTLKYFPAGDKEVISYTGNRDLETLSKFLDNGG 406
BLAST of Protein disulfide-isomerase vs. Ensembl Medaka
Match: pdia2 (protein disulfide-isomerase [Source:NCBI gene;Acc:101164281]) HSP 1 Score: 107.842 bits (268), Expect = 1.313e-24 Identity = 65/232 (28.02%), Postives = 117/232 (50.43%), Query Frame = 1
Query: 760 SDFIFSKSFVGHYHYFVPIIFKSFPIPLNEMKAEIRKIAKELDGKAIFIHFDISKKKVQRFLEHLSIPENEGFRVVESSEHLVNFKPENPLNLNGTYMLSFIRQVMDGTAEPELMASEPRENWHLEPIKHLTRKTYDQVVMDKTKNVFVIIYAPDCPYSREMLELLDKLGEMYKDDENVLLAKLDSSVDELPRIRVRSTPMMFLYLKDTNERIKFHGERTIENLKKFIESNG 1455
+D IF+ H F+ +S L E K +A+E GK ++I D++ V L + + E + V ++N + + + +RQ+ + EP L + E E+W P+K L K ++ V MD TKNVFV YAP C + +E+ + ++LGE+Y D +++++AK+D++ +E+ + + P + + E I + G R +E L KF+++ G
Sbjct: 224 ADKIFTSRVRLHCLLFINSTVESQMSLLEESKT----VAREFKGKVLYILIDMTTA-VSHVLNYFGVLEKDSPTV-----RMINMDTQKKFKIASEMTIDSLRQL---SQEPYLRSEEIPEDWDKGPVKVLVAKNFETVAMDPTKNVFVEFYAPWCGHCKELAPIWEQLGEIYADHDDIIIAKMDATANEVESVAIDGFPTLKYFPAGDKEVISYTGNRDLETLSKFLDNGG 442 HSP 2 Score: 50.0618 bits (118), Expect = 4.551e-6 Identity = 30/101 (29.70%), Postives = 49/101 (48.51%), Query Frame = 2
Query: 110 IEEDDHCLLLTDQNWDYAHKIYEYILVFFYKPDCDQCTLSDEIFVYAAKHAKETKHTVKFAFVDAANEKTIATLEQIETVPVMKFYRNKTGVQYLRTQGKE 412
IEE+ ++L N+D A +++V FY P C C + I+ AA KE ++ A VDA EK +A +++ P +K + N + + G E
Sbjct: 65 IEEEQGIMVLHINNFDRALSETRHLMVEFYAPWCGYCRRFEPIYAEAAGMLKEEGSEMRLAKVDAIEEKELAEEFNVDSFPTVKLFMNGDRKEPIEYTGNE 165
BLAST of Protein disulfide-isomerase vs. Planmine SMEST
Match: SMESG000078546.1 (SMESG000078546.1) HSP 1 Score: 696.427 bits (1796), Expect = 0.000e+0 Identity = 337/344 (97.97%), Postives = 340/344 (98.84%), Query Frame = 1
Query: 511 CVRMHFVDDIKDFEIVASMHDDVEFRLLKDAELCQRFNLPTTENSIGIYQYDFGIQHTVSGKLTRNIMNDFIIKHHVPIYSEFSDFIFSKSFVGHYHYFVPIIFKSFPIPLNEMKAEIRKIAKELDGKAIFIHFDISKKKVQRFLEHLSIPENEGFRVVESSEHLVNFKPENPLNLNGTYMLSFIRQVMDGTAEPELMASEPRENWHLEPIKHLTRKTYDQVVMDKTKNVFVIIYAPDCPYSREMLELLDKLGEMYKDDENVLLAKLDSSVDELPRIRVRSTPMMFLYLKDTNERIKFHGERTIENLKKFIESNGQDGNEQQFLEIDHLQHARLTENGLVHEEL 1542
C+ + V+DIKDFEIVASMHDDVEFRLLKDAELCQRFNLPTTENSIGIYQYDFGIQHTVSGKLTR IMNDFIIKHHVPIYSEFSDFIFSKSFVGHYHYFVPIIFKSFPIPLNEMKAEIRKIAKELDGKAIFIHFDISKKKVQRFLEHLSIPENEGFRVVESSEHLVNFKPENPLNLNGTYMLSFIRQVMDGTAEPELMASEPRENWHLEPIKHLTRKTYDQVVMDKTKNVFVIIYAPDCPYSREMLELLDKLGEMYKDDENVLLAKLDSSVDELPRIRVRSTPMMFLYLKDTNERIKFHGERTIENLKKFIESNGQDGNEQQFLEIDHLQHARLTENGLVHEEL
Sbjct: 164 CILSNSVEDIKDFEIVASMHDDVEFRLLKDAELCQRFNLPTTENSIGIYQYDFGIQHTVSGKLTRKIMNDFIIKHHVPIYSEFSDFIFSKSFVGHYHYFVPIIFKSFPIPLNEMKAEIRKIAKELDGKAIFIHFDISKKKVQRFLEHLSIPENEGFRVVESSEHLVNFKPENPLNLNGTYMLSFIRQVMDGTAEPELMASEPRENWHLEPIKHLTRKTYDQVVMDKTKNVFVIIYAPDCPYSREMLELLDKLGEMYKDDENVLLAKLDSSVDELPRIRVRSTPMMFLYLKDTNERIKFHGERTIENLKKFIESNGQDGNEQQFLEIDHLQHARLTENGLVHEEL 507 HSP 2 Score: 350.132 bits (897), Expect = 6.127e-115 Identity = 168/182 (92.31%), Postives = 172/182 (94.51%), Query Frame = 2
Query: 32 MSKSLITFALFSLSLSFYCNGDEIPIIEEDDHCLLLTDQNWDYAHKIYEYILVFFYKPDCDQCTLSDEIFVYAAKHAKETKHTVKFAFVDAANEKTIATLEQIETVPVMKFYRNKTGVQYLRTQGKEEVIQWLTDRVNYELKPISTLDDGKNTLLNNLLVVFGCIL*MILRTLKSWPVCMMM 577
MSKSLITFALFSLSLSFYCNGDEIPIIEEDDHCLLLTDQNWDYAHKIYEYILVFFYKPDCDQCTLSDEIFVYAAKHAKETKHTVKFAFVDAANEKTIATLEQIETVPVMKFYRNKTGVQYLRTQGKEEVIQWLTDRVNYELKPISTLDDGKNTLLNNLLVVFGCIL + +K + + M
Sbjct: 1 MSKSLITFALFSLSLSFYCNGDEIPIIEEDDHCLLLTDQNWDYAHKIYEYILVFFYKPDCDQCTLSDEIFVYAAKHAKETKHTVKFAFVDAANEKTIATLEQIETVPVMKFYRNKTGVQYLRTQGKEEVIQWLTDRVNYELKPISTLDDGKNTLLNNLLVVFGCILSNSVEDIKDFEIVASM 182
BLAST of Protein disulfide-isomerase vs. Planmine SMEST
Match: SMESG000023147.1 (SMESG000023147.1) HSP 1 Score: 166.392 bits (420), Expect = 8.018e-56 Identity = 93/306 (30.39%), Postives = 166/306 (54.25%), Query Frame = 1
Query: 541 KDFEIVASMHDDVEFRLLKDAELCQRFNLPTTENSIGIYQYDFGIQHTVSGKLTRNIMNDFIIKHHVPIYSEFSDFIFSKSFVGHYHYFVPIIFKSFPIPLNEMKAEIRKIAKELDGKAIFIHFDISKKKVQRFLEHLSIPENE--GFRVVESSEHLVNFKPENPLNLNGTYMLSFIRQVMDGTAEPELMASEPRENWHLEPIKHLTRKTYDQVVMDKTKNVFVIIYAPDCPYSREMLELLDKLGEMYKDDENVLLAKLDSSVDELPRIRVRSTPMMFLYLKDTNERIKFHGERTIENLKKFIESN 1452
K FE VA DDV F + + F + + ++ + ++D G ++ +G + FI K+ +PI EF+ K F G V E+K + AK+ G+ +F+ + ++ R LE + + + FR+++ + +V FKP++ ++ + F++ V+DG +P +M E E+W P+K L K +D V DK+K VFV YAP C + +++ + D+LGE YKD+ ++++AK+DS+ +E+ +R++S P + + KD++E + F G+RT+E KKFI+SN
Sbjct: 167 KAFESVADSKDDVVFGVTSQKAVFDEFKVSSDDSIVLFKKFDEG-RNDFTGPFVDKDIRTFIDKYQLPIVIEFNQETAGKIFGGSIKKHVLSFISKKSEKYAELKGQFETSAKKFLGQVLFVIINTDEEDNDRVLEFFGMAKTDTPSFRMIQLEDDMVKFKPDDA-TISSENLNLFVQSVLDGKVKPHMMTQEIPEDWDKNPVKVLVGKNFDSVARDKSKAVFVEFYAPWCGHCKQLAPIWDQLGETYKDNTDIVIAKMDSTANEVEGVRIQSFPTIKYFPKDSDEMVDFEGDRTLETFKKFIDSN 470 HSP 2 Score: 70.8626 bits (172), Expect = 8.018e-56 Identity = 43/158 (27.22%), Postives = 80/158 (50.63%), Query Frame = 2
Query: 47 ITFALFSLSLSFYCNGDEIPIIEEDDHCLLLTDQNWDYAHKIYEYILVFFYKPDCDQCTLSDEIFVYAAKHAKETKHTVKFAFVDAANEKTIATLEQIETVPVMKFYRNKTGVQYLRTQGKEEVIQWLTDRVNYELKPISTLDDGKNTLLNNLLVVFG 520
++ LF +L+ CN D I E++ L+LT+ N++ + +Y+LV FY P C C + AA+ KE +K A VDA E +A+ +I+ P +KF+++ + Y + + +I WL + + ++++ K + + +VV G
Sbjct: 4 LSIVLFCFALA-QCNAD----ITEEEGVLVLTNSNFNEVIEKNKYVLVEFYAPWCGHCKALAPEYASAAEKLKEKNSIIKLAKVDATVENDLASKFKIQGYPTLKFFKDGKVMDYGGGRTADTIISWLEKKTGPPAATLKSVEEAKALIESKDVVVVG 156
BLAST of Protein disulfide-isomerase vs. Planmine SMEST
Match: SMESG000009885.1 (SMESG000009885.1) HSP 1 Score: 102.064 bits (253), Expect = 2.991e-27 Identity = 81/323 (25.08%), Postives = 158/323 (48.92%), Query Frame = 1
Query: 541 KDFEIVASMHDDVEFRLLKDAELCQRFNLPTTENSIGIYQYD-----FGIQHTVSGKLTRNIMNDFIIKHHVPIYSEFSDF------IFSKSFVGHYHYFVPII---FKSFPIPLNEMKAEIRKIAKELDGKAIFIHFDISKKKVQRFLEHLSIPENE--GFRVVE--SSEHLVNFKPENPLNLNGTYMLSFIRQVMDGTAEPELMASEPRENWHLEPIKHLTRKTYDQVVMDKTKNVFVIIYAPDCPYSREMLELLDKLGEMYKDDENVLLAKLDSSVDELPRIRVRSTPMMFLYLKDTNERIKFHGERTIENLKKFIESNG 1455
K F+ VA + + + ++ + L +++ ++ + Q+D F ++ T +N+ +FIIK+ P+ SEF + IF + + +Y V II K F + K ++K AK GK F++ + FL L + + + +R +E V ++P + + +++F++ V+DG P + + + W+ P+K L Y++VV ++ ++VFV++ A C ++ + L ++D V +A +D +++ RV P FLY K + + I+F GERT+ +LK+F++SNG
Sbjct: 165 KTFQKVAKSTEKLPWIIVTNETLFNVYSIRLDDSIVMFRQFDDPRIDFAVEFT-----EKNV-KEFIIKYSSPLLSEFHNRKRKIPEIFDTAIL---NYLVSIIDEKHKKFTL----HKMMLQKSAKLFLGKVKFVYVKLDNPATHYFLTVLRLNKEDIPTYRFMELFPDYRTVIYRPVDE-KMTAKRIVTFVQNVLDGNLSPYYRSEKLHQRWNKYPVKMLVGSNYEEVVKNENRSVFVLLCAEKCKQCSKLRHMWHNLAIQFQDQPEVWIATIDVDKNDIRNARVEKFPTFFLYPKGSQKAIEFDGERTLNDLKQFVDSNG 473 HSP 2 Score: 39.2762 bits (90), Expect = 2.991e-27 Identity = 33/159 (20.75%), Postives = 60/159 (37.74%), Query Frame = 2
Query: 44 LITFALFSLSLSFYCNGDEIPIIEEDDHCLLLTDQNWDYAHKIYEYILVFFYKPDCDQCTLSDEIFVYAAKHAKETKHTVKFAFVDAANEKTIATLEQIETVPVMKFYRNKTGVQYLRTQGKEEVIQWLTDRVNYELKPISTLDDGKNTLLNNLLVVFG 520
+I F +F +S+ I E H L N + +++LV FY C+QC + F AK + + V ++ I I +P +K ++ Y + QW+ +R++ E + L+ K + L + G
Sbjct: 1 MINFWIFGISVGLVHT-----IYENFPHVKPLDSVNLKKRILLEKFVLVNFYATKCEQCVEFESTFSLVAKMLTDIRPDVYIGSLNCFENTQIMREYDIPNIPSVKLFQKTRSFDYRAVESTLRFAQWVFERMDEEFIIVDRLEILKELVETELFMAVG 154
BLAST of Protein disulfide-isomerase vs. Planmine SMEST
Match: SMESG000069732.1 (SMESG000069732.1) HSP 1 Score: 102.449 bits (254), Expect = 4.426e-23 Identity = 77/303 (25.41%), Postives = 146/303 (48.18%), Query Frame = 1
Query: 556 VASMHDDVEFRLLKDAELCQRFNLPTTENSIGIYQYDFGIQHTVSGKLTRNIMNDFIIKHHVPIYSEFSDFIFSKSFVGHYHYFVPIIFKSFPIPLNEMKAEIRKIAKELDGKAI------FIHFDISKKKVQRFLEHLSIP-ENEGFRVVESSEHLVNFKPENPLNLNGTYMLSFIRQVMDGTAEPELMASEPRENWHLEPIKHLTRKTYDQVVMDKTKNVFVIIYAPDCPYSREMLELLDKLGEMYKDDENVLLAKLDSSVDELPRIRVRSTPMMFLYLKDTNERIKFHGERTIENLKKFI 1443
A + DDV+F ++ F+ +I I + D + G++ + + F+ + +P +S I K F + + ++F M + + KEL+ AI F+ D++ ++H ++ N V+ ++H F P +NG + F+ V +G L + ENW+ EP+K L K +++V ++K K VFV YAP C Y +++ + ++L + D ++++AKLD + +++ ++S P + L+LKD+NE + + G RT E LK+F+
Sbjct: 169 AAELIDDVQFATMEKHLFHSLFSNTDQTKAILIRKIDNNLIPFGKGEINQEDVIKFVRSNEIPSVVRYSFDIGGKVFQNSHRFMHFMVF---------MDDKFEEAHKELEEAAINHPEITFVMTDVTDNTTSSLIKHFNVDLSNLPHLVLSDAKHKRLFLPGFN-EINGKRIDQFLMDVKNGKIGQFLKSQNIPENWNSEPVKILVGKNFEEVALNKQKTVFVEFYAPWCNYCKQLEPIWERLAKELLDVPDLIIAKLDKTENDIKNFEIKSFPTLKLFLKDSNEVVDYSGPRTRERLKEFL 461
BLAST of Protein disulfide-isomerase vs. Planmine SMEST
Match: SMESG000074835.1 (SMESG000074835.1) HSP 1 Score: 88.1965 bits (217), Expect = 1.645e-18 Identity = 53/197 (26.90%), Postives = 101/197 (51.27%), Query Frame = 1
Query: 877 KELDGKAIFIHFDI-SKKKVQRFLE--HLSIPENEGFRVVESSEHLVNFKPENPLNLNGTYMLSFIRQVMDGTAEPELMASEPRENWHLEPIKHLTRKTYDQVVMDKTKNVFVIIYAPDCPYSREMLELLDKLGEMYKDDENVLLAKLDSSVDELPRIRVRSTPMMFLYLKDTNERIKFHGERTIENLKKFIESNGQ 1458
K + GKAI I FDI + + L L+I + F V+ + P ++ ++L ++ +G+ P + NW+ + L + Y V +K V V Y+P C +S + ++ ++LGE YK+ +++++K++S+++E+ + STP +FLY K ++F ER + N +FIE++G+
Sbjct: 181 KTIRGKAISILFDIKTSPDIDETLNILDLNISDTPTFAFVKVEDFEELKYPSFTKSITSEHILKLFEKIRNGSRRPNFKSESLSPNWNTSNVISLVGENYKNVTENKNFTVLVNFYSPSCHHSGNLDKIWEELGEFYKNKSDIVISKINSNLNEIDGFPIYSTPSVFLYRKTNKIPLRFENERNLNNFIEFIENDGK 377 The following BLAST results are available for this feature:
BLAST of Protein disulfide-isomerase vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99) Total hits: 5
BLAST of Protein disulfide-isomerase vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99) Total hits: 5
BLAST of Protein disulfide-isomerase vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99) Total hits: 3
BLAST of Protein disulfide-isomerase vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99) Total hits: 5
BLAST of Protein disulfide-isomerase vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99) Total hits: 5
BLAST of Protein disulfide-isomerase vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99) Total hits: 5
BLAST of Protein disulfide-isomerase vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt) Total hits: 5
BLAST of Protein disulfide-isomerase vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL) Total hits: 5
BLAST of Protein disulfide-isomerase vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99) Total hits: 5
BLAST of Protein disulfide-isomerase vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99) Total hits: 3
BLAST of Protein disulfide-isomerase vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46) Total hits: 1
BLAST of Protein disulfide-isomerase vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46) Total hits: 5
BLAST of Protein disulfide-isomerase vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99) Total hits: 5
BLAST of Protein disulfide-isomerase vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST) Total hits: 5
Analyses
This transcript is derived from or has results from the following analyses Sequences
The following sequences are available for this feature:
transcript sequence >SMED30014062 ID=SMED30014062|Name=Protein disulfide-isomerase|organism=Schmidtea mediterranea sexual|type=transcript|length=1591bpback to top protein sequence of SMED30014062-orf-1 >SMED30014062-orf-1 ID=SMED30014062-orf-1|Name=SMED30014062-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=177bp LIFVFHHNFIMSKSLITFALFSLSLSFYCNGDEIPIIEEDDHCLLLTDQNback to top protein sequence of SMED30014062-orf-2 >SMED30014062-orf-2 ID=SMED30014062-orf-2|Name=SMED30014062-orf-2|organism=Schmidtea mediterranea sexual|type=polypeptide|length=342bp MHFVDDIKDFEIVASMHDDVEFRLLKDAELCQRFNLPTTENSIGIYQYDFback to top Annotated Terms
The following terms have been associated with this transcript:
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
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