ATP binding cassette subfamily A member 1

Overview
NameATP binding cassette subfamily A member 1
Smed IDSMED30014020
Length (bp)2356
Neoblast Clusters

Zeng et. al., 2018




▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 



 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)




Explore this single cell expression dataset with our NB Cluster Shiny App




 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of ATP binding cassette subfamily A member 1 (SMED30014020) t-SNE clustered cells

Violin plots show distribution of expression levels for ATP binding cassette subfamily A member 1 (SMED30014020) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of ATP binding cassette subfamily A member 1 (SMED30014020) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for ATP binding cassette subfamily A member 1 (SMED30014020) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017




Hover the mouse over a column in the graph to view average RPKM values per sample.
Sort Descending | Sort Ascending | Only Non-Zero Values | Tile/Chart | Reset

Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020




SMED30014020

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 35

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
intestinal phagocyteSMED30014020h1SMcG0002123 Contig3771GPL15192PMID:23079596
Forsthoefel et al., 2012
FACS sorted cell population asexual adult cDNA to DNA expression microarray evidence
intestinal phagocyteSMED30014020h1SMcG0012030 Contig3640GPL15192PMID:23079596
Forsthoefel et al., 2012
FACS sorted cell population asexual adult cDNA to DNA expression microarray evidence
intestinal phagocyteSMED30014020h1SMcG0012029 Contig3771GPL15192PMID:23079596
Forsthoefel et al., 2012
FACS sorted cell population asexual adult cDNA to DNA expression microarray evidence
intestinal phagocyteSMED30014020h1SMcG0012029 Contig3640GPL15192PMID:23079596
Forsthoefel et al., 2012
FACS sorted cell population asexual adult cDNA to DNA expression microarray evidence
intestinal phagocyteSMED30014020h1SMcG0012028 Contig3771GPL15192PMID:23079596
Forsthoefel et al., 2012
FACS sorted cell population asexual adult cDNA to DNA expression microarray evidence
intestinal phagocyteSMED30014020h1SMcG0012028 Contig3640GPL15192PMID:23079596
Forsthoefel et al., 2012
FACS sorted cell population asexual adult cDNA to DNA expression microarray evidence
intestinal phagocyteSMED30014020h1SMcG0012030 Contig3771GPL15192PMID:23079596
Forsthoefel et al., 2012
FACS sorted cell population asexual adult cDNA to DNA expression microarray evidence
intestinal phagocyteSMED30014020h1SMcG0012034 Contig3640GPL15192PMID:23079596
Forsthoefel et al., 2012
FACS sorted cell population asexual adult cDNA to DNA expression microarray evidence
intestinal phagocyteSMED30014020h1SMcG0012034 Contig3771GPL15192PMID:23079596
Forsthoefel et al., 2012
FACS sorted cell population asexual adult cDNA to DNA expression microarray evidence
intestinal phagocyteSMED30014020h1SMcG0012033 Contig3640GPL15192PMID:23079596
Forsthoefel et al., 2012
FACS sorted cell population asexual adult cDNA to DNA expression microarray evidence
intestinal phagocyteSMED30014020h1SMcG0012033 Contig3771GPL15192PMID:23079596
Forsthoefel et al., 2012
FACS sorted cell population asexual adult cDNA to DNA expression microarray evidence
nervous systemSMED30014020h1SMcG0012028 dd_Smed_v4_2300_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
epidermisSMED30014020h1SMcG0012028 dd_Smed_v4_2300_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
cephalic gangliaSMED30014020h1SMcG0012028 dd_Smed_v4_2300_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
neuronSMED30014020h1SMcG0012028 dd_Smed_v4_2300_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
whole organism asexual adult colorimetric in situ hybridization evidence
neoblastSMED30014020h1SMcG0012028 dd_Smed_v4_2300_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
parenchymal cellSMED30014020h1SMcG0012028 dd_Smed_v4_2300_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
gutSMED30014020h1SMcG0012028 dd_Smed_v4_2300_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
nervous systemSMED30014020h1SMcG0012029 dd_Smed_v4_2300_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
epidermisSMED30014020h1SMcG0012029 dd_Smed_v4_2300_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
cephalic gangliaSMED30014020h1SMcG0012029 dd_Smed_v4_2300_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
neuronSMED30014020h1SMcG0012029 dd_Smed_v4_2300_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
whole organism asexual adult colorimetric in situ hybridization evidence
neoblastSMED30014020h1SMcG0012029 dd_Smed_v4_2300_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
parenchymal cellSMED30014020h1SMcG0012029 dd_Smed_v4_2300_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
gutSMED30014020h1SMcG0012029 dd_Smed_v4_2300_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
Smed sexual biotypeSMED30014020h1SMcG0012028 Contig35762newmark_estsPMID:29674431
Fincher et al., 2018
FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
Smed sexual biotypeSMED30014020h1SMcG0012028 Contig35762uc_Smed_v2PMID:29674431
Fincher et al., 2018
FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
testisSMED30014020h1SMcG0002123 Contig3771GPL15192PMID:28434803
Rouhana et al., 2017
whole organism adult hermaphrodite colorimetric in situ hybridization evidence
testisSMED30014020h1SMcG0012029 Contig3771GPL15192PMID:28434803
Rouhana et al., 2017
whole organism adult hermaphrodite colorimetric in situ hybridization evidence
testisSMED30014020h1SMcG0012028 Contig3771GPL15192PMID:28434803
Rouhana et al., 2017
whole organism adult hermaphrodite colorimetric in situ hybridization evidence
testisSMED30014020h1SMcG0012030 Contig3771GPL15192PMID:28434803
Rouhana et al., 2017
whole organism adult hermaphrodite colorimetric in situ hybridization evidence
testisSMED30014020h1SMcG0012034 Contig3771GPL15192PMID:28434803
Rouhana et al., 2017
whole organism adult hermaphrodite colorimetric in situ hybridization evidence
testisSMED30014020h1SMcG0012033 Contig3771GPL15192PMID:28434803
Rouhana et al., 2017
whole organism adult hermaphrodite colorimetric in situ hybridization evidence
epidermisSMED30014020h1SMcG0012028 dd_Smed_v4_2300_0_1dd_Smed_v4PMID:28292427
Wurtzel et al., 2017
whole organism asexual adult single-cell RNA-sequencing evidence
epidermisSMED30014020h1SMcG0012029 dd_Smed_v4_2300_0_1dd_Smed_v4PMID:28292427
Wurtzel et al., 2017
whole organism asexual adult single-cell RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
BLAST of ATP binding cassette subfamily A member 1 vs. Ensembl Human
Match: ABCA1 (ATP binding cassette subfamily A member 1 [Source:HGNC Symbol;Acc:HGNC:29])

HSP 1 Score: 274.248 bits (700), Expect = 5.060e-77
Identity = 178/561 (31.73%), Postives = 295/561 (52.58%), Query Frame = 1
Query:  739 RNFENFFGNSNIFDTISSWVFGKIYFSPNSPLTREIMRRANITFETLDYIRLASIEWR-LHFRDWI-NEAVNNSKLINELKSCKSWYFYFDNNLCE---TVNAVLNF-----QTIQS----------ILNKISLMFSLLEKTLNCTELNKFMPINESITVENFIKQPM--KSVFAVLVINDTFRYLTPSNATF---LSYQIRIPENQIDSTKHFKVTDKFWTAEPRRETLRDFKYYTSGFLLLQEAIDRAFIEIVTNNETIDVGSSMQIMPYPCYVDDMFIRFITNMMPFMLVIAWVPSVTGLIKSIVYEKERRLKEFMRVMGLGNSVHWIGWFLSTVVVLIFPVTIMXXXXXXXXXXXXXXXXXXXXXXXXXXXXXICQVFMISLFFSNANLASVAGGVIYFILYMPFVVFIRMQSDLSTGFYYLGGLSAQVAFCNAINFIGYWEQSTEGAHFGNLFDGAIIDLKFGVGHCMLMLIVDSVLYLSVAWYVESVFPGQYGVGKAWYFLFTRNYWRAKENISLAHDINNSAQLIIDYDSEGNFENEYTDLRVGISIRNLVKTY 2346
            +N E+   +  I+  +   + GKI ++P++P TR++M   N TF+ L         W  L  + W   E      L+  L   +    +++  L     T   ++ F     + +QS            N+ +     + + + C  LNK  PI   + + N   + +  +  +A +V    F  +TP +      + Y+IR+  + ++ T   K+ D +W   PR +   D +Y   GF  LQ+ +++A I ++T  E    G  MQ MPYPCYVDD+F+R ++  MP  + +AW+ SV  +IK IVYEKE RLKE MR+MGL NS+ W  WF+S+++ L+    ++ ++L   ++L +S  +VVF+ L ++ V  I Q F+IS  FS ANLA+  GG+IYF LY+P+V+ +  Q  +         L + VAF     +   +E+   G  + NLF+  + +  F +   + M++ D+ LY  + WY+E+VFPGQYG+ + WYF  T++YW  +E+   +H  +N  ++     SE   E E T L++G+SI+NLVK Y
Sbjct:  360 KNLESSPLSRIIWKALKPLLVGKILYTPDTPATRQVMAEVNKTFQELAVFHDLEGMWEELSPKIWTFMENSQEMDLVRMLLDSRDNDHFWEQQLDGLDWTAQDIVAFLAKHPEDVQSSNGSVYTWREAFNETNQAIRTISRFMECVNLNKLEPIATEVWLINKSMELLDERKFWAGIV----FTGITPGSIELPHHVKYKIRMDIDNVERTN--KIKDGYWDPGPRADPFEDMRYVWGGFAYLQDVVEQAIIRVLTGTEK-KTGVYMQQMPYPCYVDDIFLRVMSRSMPLFMTLAWIYSVAVIIKGIVYEKEARLKETMRIMGLDNSILWFSWFISSLIPLLVSAGLLVVILKLGNLLPYSDPSVVFVFLSVFAVVTILQCFLISTLFSRANLAAACGGIIYFTLYLPYVLCVAWQDYVGFTLKIFASLLSPVAFGFGCEYFALFEEQGIGVQWDNLFESPVEEDGFNLTTSVSMMLFDTFLYGVMTWYIEAVFPGQYGIPRPWYFPCTKSYWFGEESDEKSHPGSNQKRI-----SEICMEEEPTHLKLGVSIQNLVKVY 908          
BLAST of ATP binding cassette subfamily A member 1 vs. Ensembl Human
Match: ABCA7 (ATP binding cassette subfamily A member 7 [Source:HGNC Symbol;Acc:HGNC:37])

HSP 1 Score: 234.572 bits (597), Expect = 8.943e-64
Identity = 162/540 (30.00%), Postives = 269/540 (49.81%), Query Frame = 1
Query:  796 VFGKIYFSPNSPLTREIMRRANITFETLDYIRLASIEWRL---HFRDWINEAVNNS---KLINELKSCKSWYFYFDNNLCETVNAVLNFQTI----QSILNKISLMFSLLEKTLNCTELNKF-MPINESITVENFIKQPMKSVFAVLVI-------NDTFRYLTPS-NATFLSYQIRIPENQIDS-TKHFKVTDKFWTAEPRRETLRDFKYYTSGFLLLQEAIDRAFIEIVTNNETIDVGSSMQIMPYPCYVDDMFIRFITNMMPFMLVIAWVPSVTGLIKSIVYEKERRLKEFMRVMGLGNSVHWIGWFLSTVVVLIFPVTIMXXXXXXXXXXXXXXXXXXXXXXXXXXXXXICQVFMISLFFSNANLASVAGGVIYFILYMPFVVFIRMQSDLSTGFYYLGGLSAQVAFCNAINFIGYWEQSTEGAHFGNLFDGAIIDLKFGVGHCMLMLIVDSVLYLSVAWYVESVFPGQYGVGKAWYFLFTRNYWRAKENISLAHDINNSAQLIIDYDSEGNFENEYTDLRVGISIRNLVKTYPGA 2355
            + GK+ F+P++P TR++M + N TFE L  +R     W +       ++N++ N +   +L+      +        +  E + + L+  +     Q     +  +   L +   C  L+K     +E+  V   ++   +  F   V+       +D   + TP      +  +IR+    ID  T+  K+ D+FW   P  + L D +Y   GF+ LQ+ ++RA + +++       G  +Q MPYPCYVDD+F+R ++  +P  L +AW+ SVT  +K++V EKE RL++ MR MGL  +V W+GWFLS +   +    ++ L+L    IL +S   VVFL L  + V+ + Q F++S FFS ANLA+  GG+ YF LY+P+V+ +  +  L  G      L + VAF      +   E+  EGA + N+      D+ F +     +L++D+ LY    WY+E+V PGQYG+ + W F F R+YW             + A      D +   E     L  G+S+R+L K +PG+
Sbjct:  291 ILGKLLFAPDTPFTRKLMAQVNRTFEELTLLRDVREVWEMLGPRIFTFMNDSSNVAMLQRLLQMQDEGRRQPRPGGRDHMEALRSFLDPGSGGYSWQDAHADVGHLVGTLGRVTECLSLDKLEAAPSEAALVSRALQLLAEHRFWAGVVFLGPEDSSDPTEHPTPDLGPGHVRIKIRM---DIDVVTRTNKIRDRFWDPGPAADPLTDLRYVWGGFVYLQDLVERAAVRVLSGANP-RAGLYLQQMPYPCYVDDVFLRVLSRSLPLFLTLAWIYSVTLTVKAVVREKETRLRDTMRAMGLSRAVLWLGWFLSCLGPFLLSAALLVLVLKLGDILPYSHPGVVFLFLAAFAVATVTQSFLLSAFFSRANLAAACGGLAYFSLYLPYVLCVAWRDRLPAGGRVAASLLSPVAFGFGCESLALLEEQGEGAQWHNVGTRPTADV-FSLAQVSGLLLLDAALYGLATWYLEAVCPGQYGIPEPWNFPFRRSYWCGPR------PPKSPAPCPTPLDPKVLVEEAPPGLSPGVSVRSLEKRFPGS 819          

HSP 2 Score: 55.4546 bits (132), Expect = 4.358e-7
Identity = 32/82 (39.02%), Postives = 48/82 (58.54%), Query Frame = 1
Query:   88 FTKQLKVLLWKNFRLKKRKPITLISEXXXXXXXXXXXXXXRNSIFKFKMDHCEFKEKSMASMGFVPFILDFFCTFNTTCYNK 333
            F  QL +LLWKNF  ++R+P+ L+ E+L PL +  I+V VR+S    +   C F  K + S G VP++    C  N TC+ +
Sbjct:    3 FWTQLMLLLWKNFMYRRRQPVQLLVELLWPLFLFFILVAVRHSHPPLEHHECHFPNKPLPSAGTVPWLQGLICNVNNTCFPQ 84          
BLAST of ATP binding cassette subfamily A member 1 vs. Ensembl Human
Match: ABCA4 (ATP binding cassette subfamily A member 4 [Source:HGNC Symbol;Acc:HGNC:34])

HSP 1 Score: 219.55 bits (558), Expect = 7.843e-59
Identity = 161/554 (29.06%), Postives = 271/554 (48.92%), Query Frame = 1
Query:  796 VFGKIYFSPNSPLTREIMRRANITFETLDYIRLASIEWRLHFRDWINEAVNNSKLINELKSC---KSWYFYFDNNLCE---TVNAVLNFQ---------------TIQSILNKISLMFSLLEKTLNCTELNKFMPINESITVENFIKQPMKSVF------AVLVINDTFRYLTPSNATFLSYQIRIPENQIDSTKHFKVTDKFWTAEPRRETLRDFKYYTSGFLLLQEAIDRAFIEIVTNNETIDVGSSMQIMPYPCYVDDMFIRFITNMMPFMLVIAWVPSVTGLIKSIVYEKERRLKEFMRVMGLGNSVHWIGWFLSTVVVLIFPVTIMXXXXXXXXXXXXXXXXXXXXXXXXXXXXXICQVFMISLFFSNANLASVAGGVIYFILYMPFVVFIRMQSDLSTGFYYLGGLSAQVAFCNAINFIGYWEQSTEGAHFGNLFDGAIIDLKFGVGHCMLMLIVDSVLYLSVAWYVESVFPGQYGVGKAWYFLFTRNYWRAKENISLAHD--INNSAQLIIDYDSEGN--------FENEYTDLRVGISIRNLVKTY 2346
            + GKI ++P+SP  R I++ AN TFE L+++R     W       I    +NS  +N ++      +   + +  L E   T  A+LNF                  + I N       L+ + L C  L+KF    ES   E  + Q   S+       A +V  D + + T S    + Y+IR+  + ++ T   K+ D++W + PR + + DF+Y   GF  LQ+ +++         E   VG  +Q MPYPC+VDD F+  +    P  +V+AW+ SV+  +KSIV EKE RLKE ++  G+ N+V W  WFL +  ++   + ++++ +++  IL +S   ++FL LL +  + I   F++S FFS A+LA+   GVIYF LY+P ++    Q  ++        L + VAF     ++  +E+   G  + N+ +      +F     M M+++D+ +Y  +AWY++ VFPG YG    WYFL   +YW   E  S   +  +  +  L  + +   +        FE E+     G+ ++NLVK +
Sbjct:  394 LMGKILYTPDSPAARRILKNANSTFEELEHVRKLVKAWE-EVGPQIWYFFDNSTQMNMIRDTLGNPTVKDFLNRQLGEEGITAEAILNFLYKGPRESQADDMANFDWRDIFNITDRTLRLVNQYLECLVLDKF----ESYNDETQLTQRALSLLEENMFWAGVVFPDMYPW-TSSLPPHVKYKIRMDIDVVEKTN--KIKDRYWDSGPRADPVEDFRYIWGGFAYLQDMVEQGITRSQVQAEA-PVGIYLQQMPYPCFVDDSFMIILNRCFPIFMVLAWIYSVSMTVKSIVLEKELRLKETLKNQGVSNAVIWCTWFLDSFSIMSMSIFLLTIFIMHGRILHYSDPFILFLFLLAFSTATIMLCFLLSTFFSKASLAAACSGVIYFTLYLPHILCFAWQDRMTAELKKAVSLLSPVAFGFGTEYLVRFEEQGLGLQWSNIGNSPTEGDEFSFLLSMQMMLLDAAVYGLLAWYLDQVFPGDYGTPLPWYFLLQESYWLGGEGCSTREERALEKTEPLTEETEDPEHPEGIHDSFFEREHPGWVPGVCVKNLVKIF 938          

HSP 2 Score: 56.225 bits (134), Expect = 2.798e-7
Identity = 32/111 (28.83%), Postives = 60/111 (54.05%), Query Frame = 1
Query:   88 FTKQLKVLLWKNFRLKKRKPITLISEXXXXXXXXXXXXXXRNSIFKFKMDHCEFKEKSMASMGFVPFILDFFCTFNTTCYNKTQINWNENYSSIYAFKMFTKNLYNVYQTL 420
            F +Q+++LLWKN+ L+KR+ I  + E++ PL + ++++ +RN+   +    C F  K+M S G +P++   FC  N  C+       +    S Y   +  + +Y  +Q L
Sbjct:    3 FVRQIQLLLWKNWTLRKRQKIRFVVELVWPLSLFLVLIWLRNANPLYSHHECHFPNKAMPSAGMLPWLQGIFCNVNNPCFQSPTPGESPGIVSNYNNSILAR-VYRDFQEL 112          
BLAST of ATP binding cassette subfamily A member 1 vs. Ensembl Human
Match: ABCA12 (ATP binding cassette subfamily A member 12 [Source:HGNC Symbol;Acc:HGNC:14637])

HSP 1 Score: 192.971 bits (489), Expect = 4.916e-50
Identity = 147/562 (26.16%), Postives = 272/562 (48.40%), Query Frame = 1
Query:  784 ISSWVFGKIYFSPNSPLTREIMRRANITFETLDYIRLASIEWR------LHFRDWINEAVNNSKLINELKSCKSWYFY-----FDN-NLCETVNAV----LNFQTIQSILNKISLMFSLLEKTLNCTELNKFMPINESITVENFIKQPMKS------VFAVLVINDTFRYLTPSNATFL----SYQIRIPENQIDSTKHFKVTDKFWTAEPRRETLRDFKYYTSGFLLLQEAIDRAFIEIVTNNETIDVGSSMQIMPYPCYVDDMFIRFITNMMPFMLVIAWVPSVTGLIKSIVYEKERRLKEFMRVMGLGNSVHWIGWFLSTVVVLIFPVTIMXXXXXXXXXXXXXXXXXXXXXXXXXXXXXICQVFMISLFFSNANLASVAGGVIYFILYMPFVVFIRMQSDLSTGFYYLGGLSAQVAFCNAINFIGYWEQSTEGAHFGNLFDGAIIDLKFGVGHCMLMLIVDSVLYLSVAWYVESVFPGQYGVGKAWYFLFTRNYWRAKENIS---------------LAHDINNSAQLIIDYDSEGNFENEYTDLRVGISIRNLVKTY 2346
            +   + G+I ++P +P+T+ IM ++N+T   L  +R  S EW       ++    +N+A+    L N L++     F       D   L + ++ +    L  +    I+++++ + SL     +C   ++         +E   K+  KS      V   L  N ++     S   FL     Y IR+      +T+  +   K W   P      + + Y   F+ LQ++I+RA IE+ T   + ++   +Q +PYPC++ D F+  ++  +P +L++AWV  +   +K +VYEK+ RL E+M++MG+ +  H+  W + +V  L+  + I+ ++L + +IL  +   ++FL    Y  S I   ++IS+FF+N N+A++ G +IY I + PF+V + ++++LS        L +  AF  A  +I  +E+   G  + N++   + D     G    +++ DS +Y  +AWYV +VFPG YG+   WYF    +YW+ +   +               +  + N SA    +Y    N E E  DL VG+++  + K Y
Sbjct:  483 LKPMLLGRILYAPYNPVTKAIMEKSNVTLRQLAELREKSQEWMDKSPLFMNSFHLLNQAI--PMLQNTLRNPFVQVFVKFSVGLDAVELLKQIDELDILRLKLENNIDIIDQLNTLSSLTVNISSCVLYDRIQAAKTIDEMEREAKRLYKSNELFGSVIFKLPSNRSWHRGYDSGNVFLPPVIKYTIRMSLKTAQTTRSLRT--KIWAPGPHNSPSHN-QIYGRAFIYLQDSIERAIIELQTGRNSQEIAVQVQAIPYPCFMKDNFLTSVSYSLPIVLMVAWVVFIAAFVKKLVYEKDLRLHEYMKMMGVNSCSHFFAWLIESVGFLLVTIVILIIILKFGNILPKTNGFILFLYFSDYSFSVIAMSYLISVFFNNTNIAALIGSLIYIIAFFPFIVLVTVENELSYVLKVFMSLLSPTAFSYASQYIARYEEQGIGLQWENMYTSPVQDDTTSFGWLCCLILADSFIYFLIAWYVRNVFPGTYGMAAPWYFPILPSYWKERFGCAEVKPEKSNGLMFTNIMMQNTNPSAS--PEYMFSSNIEPEPKDLTVGVALHGVTKIY 1037          
BLAST of ATP binding cassette subfamily A member 1 vs. Ensembl Human
Match: ABCA12 (ATP binding cassette subfamily A member 12 [Source:HGNC Symbol;Acc:HGNC:14637])

HSP 1 Score: 192.971 bits (489), Expect = 4.971e-50
Identity = 147/562 (26.16%), Postives = 272/562 (48.40%), Query Frame = 1
Query:  784 ISSWVFGKIYFSPNSPLTREIMRRANITFETLDYIRLASIEWR------LHFRDWINEAVNNSKLINELKSCKSWYFY-----FDN-NLCETVNAV----LNFQTIQSILNKISLMFSLLEKTLNCTELNKFMPINESITVENFIKQPMKS------VFAVLVINDTFRYLTPSNATFL----SYQIRIPENQIDSTKHFKVTDKFWTAEPRRETLRDFKYYTSGFLLLQEAIDRAFIEIVTNNETIDVGSSMQIMPYPCYVDDMFIRFITNMMPFMLVIAWVPSVTGLIKSIVYEKERRLKEFMRVMGLGNSVHWIGWFLSTVVVLIFPVTIMXXXXXXXXXXXXXXXXXXXXXXXXXXXXXICQVFMISLFFSNANLASVAGGVIYFILYMPFVVFIRMQSDLSTGFYYLGGLSAQVAFCNAINFIGYWEQSTEGAHFGNLFDGAIIDLKFGVGHCMLMLIVDSVLYLSVAWYVESVFPGQYGVGKAWYFLFTRNYWRAKENIS---------------LAHDINNSAQLIIDYDSEGNFENEYTDLRVGISIRNLVKTY 2346
            +   + G+I ++P +P+T+ IM ++N+T   L  +R  S EW       ++    +N+A+    L N L++     F       D   L + ++ +    L  +    I+++++ + SL     +C   ++         +E   K+  KS      V   L  N ++     S   FL     Y IR+      +T+  +   K W   P      + + Y   F+ LQ++I+RA IE+ T   + ++   +Q +PYPC++ D F+  ++  +P +L++AWV  +   +K +VYEK+ RL E+M++MG+ +  H+  W + +V  L+  + I+ ++L + +IL  +   ++FL    Y  S I   ++IS+FF+N N+A++ G +IY I + PF+V + ++++LS        L +  AF  A  +I  +E+   G  + N++   + D     G    +++ DS +Y  +AWYV +VFPG YG+   WYF    +YW+ +   +               +  + N SA    +Y    N E E  DL VG+++  + K Y
Sbjct:  801 LKPMLLGRILYAPYNPVTKAIMEKSNVTLRQLAELREKSQEWMDKSPLFMNSFHLLNQAI--PMLQNTLRNPFVQVFVKFSVGLDAVELLKQIDELDILRLKLENNIDIIDQLNTLSSLTVNISSCVLYDRIQAAKTIDEMEREAKRLYKSNELFGSVIFKLPSNRSWHRGYDSGNVFLPPVIKYTIRMSLKTAQTTRSLRT--KIWAPGPHNSPSHN-QIYGRAFIYLQDSIERAIIELQTGRNSQEIAVQVQAIPYPCFMKDNFLTSVSYSLPIVLMVAWVVFIAAFVKKLVYEKDLRLHEYMKMMGVNSCSHFFAWLIESVGFLLVTIVILIIILKFGNILPKTNGFILFLYFSDYSFSVIAMSYLISVFFNNTNIAALIGSLIYIIAFFPFIVLVTVENELSYVLKVFMSLLSPTAFSYASQYIARYEEQGIGLQWENMYTSPVQDDTTSFGWLCCLILADSFIYFLIAWYVRNVFPGTYGMAAPWYFPILPSYWKERFGCAEVKPEKSNGLMFTNIMMQNTNPSAS--PEYMFSSNIEPEPKDLTVGVALHGVTKIY 1355          
BLAST of ATP binding cassette subfamily A member 1 vs. Ensembl Celegans
Match: abt-2 (ABC Transporter family [Source:UniProtKB/TrEMBL;Acc:Q1RS86])

HSP 1 Score: 173.326 bits (438), Expect = 3.394e-44
Identity = 159/559 (28.44%), Postives = 274/559 (49.02%), Query Frame = 1
Query:  766 SNIFDTISSWVFGKIYFSPNSPLTREIMRRANITFETLDYIR---------LASIEWRLHFRD-WINEAVNNSKLINELK---------SCKSWYFYFDNNLCETVNAVLNFQTIQSILNKISLMFSLLEKTLNCTELNKFMPINESITVENFIKQPMKSVFAVLVINDTFRYLT------PSNAT----FLSYQIRIPENQIDSTKHFKVTDKFWTAEPRRETLRDFKYYTSGFLLLQEAIDRAFIEIVTNNETIDVGSSMQIMPYPCYVDDMFIRFITNMMPFMLVIAWVPSVTGLIKSIVYEKERRLKEFMRVMGLGNSVHWIGWFLSTVVVLIFPVTIMXXXXXXXXXXXXXXXXXXXXXXXXXXXXXICQVFMISLFFSNANLASVAGGVIYFILYMPFVVFIRMQSDLSTGFYYLGGLSAQVAFCNAINFIGYWEQSTEGAHFGNLFDGAIIDLKFGVGHCMLMLIVDSVLYLSVAWYVESVFPGQYGVGKAWYFLFTRNYWRA---KENISLAHDINNSAQLIIDYDSEGNFENEYTDLRVGISIRNLVKTY 2346
            S I   +   + G I  +P++P+TR ++ R NI    ++++R             + RLH  D W      + KL++ +K         + ++ +F+ ++    + +   +F T    + +I+       K   C  L++F  + +   +E             + + DT +Y T       SNAT    F +Y+IR     +DST  F   D       R + L D KY T GF  LQE+IDRA +  +TN    ++G   Q  PYPC V D F   +   MP  L+I+++     L+K+IVYEKE+++KE MR MGLG++VH+I W L ++V+    V I+S++   + I  ++ + ++  VL+L++ S I      S  F+NAN+A+ A  V++F+ ++PF + +R     S  F  +  +    A  +    +  +  + E A + +L++     L   V  CM+ML+VD+ ++L +AWY+ +V PG +GV +  +F FT  YW     K  +    D       I + DS   F++E T+L + + I ++ K Y
Sbjct:  375 SPILMKVREALSGYILVTPDNPVTRRVVDRLNIPLRDIEHLRNLLYTYPSDALEFQDRLHASDLW----PASQKLLHFIKVYKNGQNQLNTRTIHFFLEHLFAPSSDEY-SFGTYTKNITEIA------NKYTGCFLLDRFRFVTDEKELET----------NAVCLMDTHQYFTGIVFNIDSNATEFDGFTTYKIRHYPEMVDSTTSF--MDSKSNPFSRDKPLIDLKYITFGFSFLQESIDRAIMSELTNQTDANLGVYAQQEPYPCTVKDTF--NVALFMPLFLLISFIFPSALLVKNIVYEKEQKIKEQMRAMGLGDAVHFISWGLISLVLNFISVLIISIISKVAKIFDYTDYTLLLFVLILFLFSSIAMSIFFSTLFTNANIATAATCVLWFVFFIPFQL-LRTDRISSPTFNRISLILPPTAMGHCFKLLESF-NAMERATWSDLWEMNNPVLGISVELCMIMLVVDTAVFLILAWYISAVAPGDFGVRQPLWFPFTLKYWAPGLYKNRVEFVDD--EHFDTIPNSDS---FDSEPTNLTLAVHINSMSKVY 901          
BLAST of ATP binding cassette subfamily A member 1 vs. Ensembl Celegans
Match: abt-2 (ABC Transporter family [Source:UniProtKB/TrEMBL;Acc:Q1RS86])

HSP 1 Score: 173.326 bits (438), Expect = 4.121e-44
Identity = 159/559 (28.44%), Postives = 274/559 (49.02%), Query Frame = 1
Query:  766 SNIFDTISSWVFGKIYFSPNSPLTREIMRRANITFETLDYIR---------LASIEWRLHFRD-WINEAVNNSKLINELK---------SCKSWYFYFDNNLCETVNAVLNFQTIQSILNKISLMFSLLEKTLNCTELNKFMPINESITVENFIKQPMKSVFAVLVINDTFRYLT------PSNAT----FLSYQIRIPENQIDSTKHFKVTDKFWTAEPRRETLRDFKYYTSGFLLLQEAIDRAFIEIVTNNETIDVGSSMQIMPYPCYVDDMFIRFITNMMPFMLVIAWVPSVTGLIKSIVYEKERRLKEFMRVMGLGNSVHWIGWFLSTVVVLIFPVTIMXXXXXXXXXXXXXXXXXXXXXXXXXXXXXICQVFMISLFFSNANLASVAGGVIYFILYMPFVVFIRMQSDLSTGFYYLGGLSAQVAFCNAINFIGYWEQSTEGAHFGNLFDGAIIDLKFGVGHCMLMLIVDSVLYLSVAWYVESVFPGQYGVGKAWYFLFTRNYWRA---KENISLAHDINNSAQLIIDYDSEGNFENEYTDLRVGISIRNLVKTY 2346
            S I   +   + G I  +P++P+TR ++ R NI    ++++R             + RLH  D W      + KL++ +K         + ++ +F+ ++    + +   +F T    + +I+       K   C  L++F  + +   +E             + + DT +Y T       SNAT    F +Y+IR     +DST  F   D       R + L D KY T GF  LQE+IDRA +  +TN    ++G   Q  PYPC V D F   +   MP  L+I+++     L+K+IVYEKE+++KE MR MGLG++VH+I W L ++V+    V I+S++   + I  ++ + ++  VL+L++ S I      S  F+NAN+A+ A  V++F+ ++PF + +R     S  F  +  +    A  +    +  +  + E A + +L++     L   V  CM+ML+VD+ ++L +AWY+ +V PG +GV +  +F FT  YW     K  +    D       I + DS   F++E T+L + + I ++ K Y
Sbjct:  412 SPILMKVREALSGYILVTPDNPVTRRVVDRLNIPLRDIEHLRNLLYTYPSDALEFQDRLHASDLW----PASQKLLHFIKVYKNGQNQLNTRTIHFFLEHLFAPSSDEY-SFGTYTKNITEIA------NKYTGCFLLDRFRFVTDEKELET----------NAVCLMDTHQYFTGIVFNIDSNATEFDGFTTYKIRHYPEMVDSTTSF--MDSKSNPFSRDKPLIDLKYITFGFSFLQESIDRAIMSELTNQTDANLGVYAQQEPYPCTVKDTF--NVALFMPLFLLISFIFPSALLVKNIVYEKEQKIKEQMRAMGLGDAVHFISWGLISLVLNFISVLIISIISKVAKIFDYTDYTLLLFVLILFLFSSIAMSIFFSTLFTNANIATAATCVLWFVFFIPFQL-LRTDRISSPTFNRISLILPPTAMGHCFKLLESF-NAMERATWSDLWEMNNPVLGISVELCMIMLVVDTAVFLILAWYISAVAPGDFGVRQPLWFPFTLKYWAPGLYKNRVEFVDD--EHFDTIPNSDS---FDSEPTNLTLAVHINSMSKVY 938          
BLAST of ATP binding cassette subfamily A member 1 vs. Ensembl Celegans
Match: abt-4 (ABC Transporter family [Source:UniProtKB/TrEMBL;Acc:Q9TXV8])

HSP 1 Score: 129.413 bits (324), Expect = 3.143e-30
Identity = 98/334 (29.34%), Postives = 171/334 (51.20%), Query Frame = 1
Query: 1366 YYTSGFLLLQEAIDRAFIEIVTNNET--IDVGSSMQI--MPYPCYVDDMFIRFITNMMPFMLVIAWVPSVTGLIKSIVYEKERRLKEFMRVMGLGNSVHWIGWFLSTVVVLIFPVTIMXXXXXXXXXXXXXXXXXXXXXXXXXXXXXICQVFMISLFFSNANLASVAGGVIYFILYMPFVVF--IRMQSDLSTGFYYLGGLSAQVAFCNAINFIGYWEQSTEGAHFGNLFDGAIIDLKFGVGHCMLMLIVDSVLYLSVAWYVESVFPGQYGVGKAWYFLFTRNYWRAKENISLAHDINNSAQL-IIDYDSEGNFENEYTDLRVGISIRNLVKTY 2346
            Y+  GF+ +Q A+D A  EI+T  +     +  S Q+   P+P Y   + I      MP +++ +++ SV  +++++V EKE RLKE+MRVMGL   ++W+  F+     L F V ++++L+ + ++ S      VFL++  + V +    FMIS F ++A  A++   V + +LY  +  F  I   +    G+  +  ++  +A    +  +  +E   +G  +G LF     D     GH ++ LIVD ++ + + WY+E+V PG  GV +  +F    +YW      S +  +++S Q   I Y      E E TDL   I++ NL KTY
Sbjct:  266 YWQEGFMTVQRAVDVAITEIITGEDAQLTPLLDSYQVSRFPFPGYSTKI-IEIGAFFMPVIVIFSFMTSVIYIVRAVVVEKEDRLKEYMRVMGLSQFINWVAHFIINYAKLTFAVIVLTILMHFVALKSDMTLMFVFLMIYAFDVVYFA--FMISSFMNSATSATLISVVFWMLLYFWYAFFSSIDQTNPYPLGYRLINCINPDIALNYGLQLLAAYETQADGLKWGELFTPPSPDNNLTFGHALIALIVDGIIMIILTWYIEAVIPGGEGVPQKPWFFVLPSYWFPN---SGSKTVDSSDQFQQIQYADHVKLEKEPTDLIPTINVVNLTKTY 593          
BLAST of ATP binding cassette subfamily A member 1 vs. Ensembl Fly
Match: ABCA (gene:FBgn0031170 transcript:FBtr0332489)

HSP 1 Score: 154.066 bits (388), Expect = 5.953e-38
Identity = 101/346 (29.19%), Postives = 175/346 (50.58%), Query Frame = 1
Query: 1336 PRRETLRDFK----YYTSGFLLLQEAIDRAFIEIVTNNETIDVGSSMQIMPYPCYVDDMFIRFITNMMPFMLVIAWVPSVTGLIKSIVYEKERRLKEFMRVMGLGNSVHWIGWFLS-----TVVVLIFPVTIMXXXXXXXXXXXXXXXXXXXXXXXXXXXXXICQVFMISLFFSNANLASVAGGVIYFILYMPFVVFIRMQSDLSTGFYYLGGLSAQVAFCNAINFIGYWEQSTEGAHFGNLFDGAIIDLKFGVGHCMLMLIVDSVLYLSVAWYVESVFPGQYGVGKAWYFLFTRNYWRAKENISLAHDINNSAQLIIDYDSEGNFENEYTDLRVGISIRNLVKTY 2346
            PR E   D      Y   GFL LQ ++  A++   +  + +     M+  P+P Y+ D  +  ++++M  +++++++   T + K I  EKE++LKE M++MGL N +HW  WF+      T+  ++  + +        ++L+ + F  +   L++Y+VS IC  FM++ FFS A+ A+   G+I+FI Y+P+   I    DLS        L +  A    I  I  +E + EG  + N F    +D    +G  M+M++V  V+Y+ +  YVE V PG +GV + W F FTR +W  +   +   DI N     ++      FE E     +G+ +R+L K +
Sbjct:  184 PRNEGDDDGGIPPGYLREGFLPLQHSLSMAYLRQKSGEQDLP-NVVMKRYPFPAYIFDPLLEGMSSIMSLIILLSFIYPCTYITKYITAEKEKQLKEVMKIMGLSNWLHWTAWFVKSFIMLTISAILIAILVKINWSEDVAVLTHANFTALVFFLIIYIVSSICFCFMMATFFSRASTAAAVTGLIWFIAYIPYSFTINSYDDLSLSSKLGWSLISNTAMGFGIKLILGFEGTGEGLQWSNFFTPVSVDDTLTLGAVMIMMLVSCVIYMIICLYVEQVMPGSFGVPRPWNFPFTREFWCGEREYTGVEDIPNGH---VEQRDPKAFETEPEGKHIGLQMRHLKKRF 525          
BLAST of ATP binding cassette subfamily A member 1 vs. Ensembl Fly
Match: ABCA (gene:FBgn0031170 transcript:FBtr0332488)

HSP 1 Score: 153.68 bits (387), Expect = 7.012e-38
Identity = 101/346 (29.19%), Postives = 175/346 (50.58%), Query Frame = 1
Query: 1336 PRRETLRDFK----YYTSGFLLLQEAIDRAFIEIVTNNETIDVGSSMQIMPYPCYVDDMFIRFITNMMPFMLVIAWVPSVTGLIKSIVYEKERRLKEFMRVMGLGNSVHWIGWFLS-----TVVVLIFPVTIMXXXXXXXXXXXXXXXXXXXXXXXXXXXXXICQVFMISLFFSNANLASVAGGVIYFILYMPFVVFIRMQSDLSTGFYYLGGLSAQVAFCNAINFIGYWEQSTEGAHFGNLFDGAIIDLKFGVGHCMLMLIVDSVLYLSVAWYVESVFPGQYGVGKAWYFLFTRNYWRAKENISLAHDINNSAQLIIDYDSEGNFENEYTDLRVGISIRNLVKTY 2346
            PR E   D      Y   GFL LQ ++  A++   +  + +     M+  P+P Y+ D  +  ++++M  +++++++   T + K I  EKE++LKE M++MGL N +HW  WF+      T+  ++  + +        ++L+ + F  +   L++Y+VS IC  FM++ FFS A+ A+   G+I+FI Y+P+   I    DLS        L +  A    I  I  +E + EG  + N F    +D    +G  M+M++V  V+Y+ +  YVE V PG +GV + W F FTR +W  +   +   DI N     ++      FE E     +G+ +R+L K +
Sbjct:  184 PRNEGDDDGGIPPGYLREGFLPLQHSLSMAYLRQKSGEQDLP-NVVMKRYPFPAYIFDPLLEGMSSIMSLIILLSFIYPCTYITKYITAEKEKQLKEVMKIMGLSNWLHWTAWFVKSFIMLTISAILIAILVKINWSEDVAVLTHANFTALVFFLIIYIVSSICFCFMMATFFSRASTAAAVTGLIWFIAYIPYSFTINSYDDLSLSSKLGWSLISNTAMGFGIKLILGFEGTGEGLQWSNFFTPVSVDDTLTLGAVMIMMLVSCVIYMIICLYVEQVMPGSFGVPRPWNFPFTREFWCGEREYTGVEDIPNGH---VEQRDPKAFETEPEGKHIGLQMRHLKKRF 525          
BLAST of ATP binding cassette subfamily A member 1 vs. Ensembl Fly
Match: ABCA (gene:FBgn0031170 transcript:FBtr0306679)

HSP 1 Score: 153.68 bits (387), Expect = 7.023e-38
Identity = 101/346 (29.19%), Postives = 175/346 (50.58%), Query Frame = 1
Query: 1336 PRRETLRDFK----YYTSGFLLLQEAIDRAFIEIVTNNETIDVGSSMQIMPYPCYVDDMFIRFITNMMPFMLVIAWVPSVTGLIKSIVYEKERRLKEFMRVMGLGNSVHWIGWFLS-----TVVVLIFPVTIMXXXXXXXXXXXXXXXXXXXXXXXXXXXXXICQVFMISLFFSNANLASVAGGVIYFILYMPFVVFIRMQSDLSTGFYYLGGLSAQVAFCNAINFIGYWEQSTEGAHFGNLFDGAIIDLKFGVGHCMLMLIVDSVLYLSVAWYVESVFPGQYGVGKAWYFLFTRNYWRAKENISLAHDINNSAQLIIDYDSEGNFENEYTDLRVGISIRNLVKTY 2346
            PR E   D      Y   GFL LQ ++  A++   +  + +     M+  P+P Y+ D  +  ++++M  +++++++   T + K I  EKE++LKE M++MGL N +HW  WF+      T+  ++  + +        ++L+ + F  +   L++Y+VS IC  FM++ FFS A+ A+   G+I+FI Y+P+   I    DLS        L +  A    I  I  +E + EG  + N F    +D    +G  M+M++V  V+Y+ +  YVE V PG +GV + W F FTR +W  +   +   DI N     ++      FE E     +G+ +R+L K +
Sbjct:  206 PRNEGDDDGGIPPGYLREGFLPLQHSLSMAYLRQKSGEQDLP-NVVMKRYPFPAYIFDPLLEGMSSIMSLIILLSFIYPCTYITKYITAEKEKQLKEVMKIMGLSNWLHWTAWFVKSFIMLTISAILIAILVKINWSEDVAVLTHANFTALVFFLIIYIVSSICFCFMMATFFSRASTAAAVTGLIWFIAYIPYSFTINSYDDLSLSSKLGWSLISNTAMGFGIKLILGFEGTGEGLQWSNFFTPVSVDDTLTLGAVMIMMLVSCVIYMIICLYVEQVMPGSFGVPRPWNFPFTREFWCGEREYTGVEDIPNGH---VEQRDPKAFETEPEGKHIGLQMRHLKKRF 547          
BLAST of ATP binding cassette subfamily A member 1 vs. Ensembl Fly
Match: CG6052 (gene:FBgn0036747 transcript:FBtr0075195)

HSP 1 Score: 130.954 bits (328), Expect = 1.147e-30
Identity = 107/397 (26.95%), Postives = 191/397 (48.11%), Query Frame = 1
Query: 1207 INDTFRYLTPSNATFLSYQIRIPENQIDSTKHFKVTDKFWTAEPRRETLRDFKYYTSGFLLLQEAIDRAFIEIVTNNETIDVGS-SMQIMPYPCYVDDMFIRFITNMMPFMLVIAWVPSVTGLIKSIVYEKERRLKEFMRVMGLGNSVHWIGWFLSTVVVLIFPV-----TIMXXXXXXXXXXXXXXXXXXXXXXXXXXXXXICQVFMISLFFSNANLASVAGGVIYFILYMPFVVFIRMQSDLSTGFYYLGGLS-----------AQVAFCNAINFIGYWEQSTEGAHFGNLFDGAIIDLKFGVGHCMLMLIVDSVLYLSVAWYVESVFPGQYGVGKAWYFLFTRNYWRAKENISLAHDINNSAQLIIDYDSEGNFENEYTDLRVGISIRNLVKTY 2346
            I DT+R    ++  FLSY      N++D+     V                  Y   GFL +Q A+  +++ + +      + +  +Q  PY  Y  D  +  +  ++PF+++++++   + + K +  EKE +LKE M+++G+ N +HW+ WF+ + ++L+  V      IM       ++L+FS +  V L L  YVV+ +C  FM+++ FS A+ AS    + +F+ Y+P+          S G+YY   LS           +  A    I+ I  WE + EG  + N+F     D    + + ++ +   S++++S+  YVE VFPG+YGV + W F+  +NYWR       + +I  S Q I+   ++        +  VGI + NL K Y
Sbjct:  164 IIDTWR----TSRLFLSYDTSGSRNRLDNDGGVPV-----------------GYIREGFLPIQHALTMSWLALASGVTDTGIPAIHLQRFPYRAYTYDQLLSGLRQLLPFVILLSFIYPASTVTKYVTSEKELQLKEIMKLIGVHNWLHWVAWFVKSYIMLMLVVFLIMSLIMVKFYASVAVLTFSSWVPVLLFLHTYVVTSVCLCFMLAVLFSKASTASAVAAIFWFLTYIPY----------SFGYYYYERLSLMSKLLISLIFSNSALGFGIHVIVMWEGTGEGITWRNMFHPVSTDDSLTLFYIIMTMSFGSIMFISICLYVEQVFPGEYGVPRRWNFMCHKNYWR---QYVPSLNIVPSFQTILHGSAKAKSCRRARE--VGIQLFNLQKNY 524          
BLAST of ATP binding cassette subfamily A member 1 vs. Ensembl Fly
Match: CG31213 (gene:FBgn0051213 transcript:FBtr0335242)

HSP 1 Score: 100.908 bits (250), Expect = 2.278e-21
Identity = 96/352 (27.27%), Postives = 166/352 (47.16%), Query Frame = 1
Query: 1354 RDFKYYTSGFLLLQEAIDRAFIEIVTNNETIDVGSSMQIMPYPCYVDDMFIRFITNMMPFMLVIAWVPSVTGLIKSIVYEKERRLKEFMRVMGLGNSVHWIGWFLSTVVVLIFPVTIMXXXXXXXXXXXXXXXXXXXXXXXXXXXXXICQVFMISLFFSNANLASVAGGVIYFILYMPFVVFIRMQSDLSTGFYYLGGLSAQVAFCNAINFIGYWEQSTEGAHFGNLFDGAIIDLKFGVGHCMLMLIVDSVLYLSVAWYVESVFPGQYGVGKAWYFLFTRNYW---------------------RAKENISLAHDINNSAQLIIDYDSEGNFENEYTDLRVGISIRNLVKTY 2346
            +DFKY+ SGFLLLQE I + FI              M   PYP YV + +      M    L+  ++P +T + K +V EKER  K  +  MG  NS+HW+ W+  ++++L+  + IM  +     I  FS    +  + L+Y+ S +   F IS FFS +  A VA  ++YF   +PF++     S ++       GL++ + +   ++ +   E  + GA +  + + A    K  +   ML++I  S + L +  Y+E+V  G++ V + W + F R YW                      ++ N+  AH       + +D  ++ NF+      ++GI +R+L KT+
Sbjct:  153 KDFKYFESGFLLLQERISKIFIFFKNAGNGKIPRVLMNHFPYPSYVPNHYAESAKAMTYMTLISFFLPCIT-IAKYVVAEKERHQKAVLTAMGFSNSIHWLAWYTKSMLLLLLCLLIMISIFSIGLIYEFSSLVCLMTIFLVYIHSLVLFAFFISSFFSRSLSAVVATILMYFSTALPFLIVGAENSSVAAQTAASIGLNSALFYI--LDSVAVMEMQSVGAQWYTIDNTASSGYKLSIVGYMLIMISISWIELLICLYIEAVRTGEFEVPQPWSYPFQRRYWCPLRYGSSVFHQGALLPLAGKNSEGNLPAAHPTRQPI-IYLDDRTQENFQRVNISKKIGIEVRSLSKTF 500          
BLAST of ATP binding cassette subfamily A member 1 vs. Ensembl Zebrafish
Match: abca1b (ATP-binding cassette, sub-family A (ABC1), member 1B [Source:ZFIN;Acc:ZDB-GENE-030131-9826])

HSP 1 Score: 254.603 bits (649), Expect = 1.108e-70
Identity = 192/646 (29.72%), Postives = 320/646 (49.54%), Query Frame = 1
Query:  559 TENLTASKPIIIQ-IFKVFCGSDE--------------NDFTEFYYKFSSISTKNVSGQTNAGSQFMNESNVTCERNFENFFGNSNIFDTISSWVFGKIYFSPNSPLTREIMRRANITFETLDYIRLASIEWRLHFRDWINEAVNNSKLINELKSCKSWYF------YFDNNLCET---VNAVLNFQTIQS--------------ILNKISLMFSLLEKTLNCTELNKFMPINESITVENFIKQPM-----KSVFAVLVINDTFRYLTPSNATFL----SYQIRIPENQIDSTKHFKVTDKFWTAEPRRETLRDFKYYTSGFLLLQEAIDRAFIEIVTNNETIDVGSSMQIMPYPCYVDDMFIRFITNMMPFMLVIAWVPSVTGLIKSIVYEKERRLKEFMRVMGLGNSVHWIGWFLSTVVVLIFPVTIMXXXXXXXXXXXXXXXXXXXXXXXXXXXXXICQVFMISLFFSNANLASVAGGVIYFILYMPFVVFIRMQSDLSTGFYYLGGLSAQVAFCNAINFIGYWEQSTEGAHFGNLFDGAIIDLKFGVGHCMLMLIVDSVLYLSVAWYVESVFPGQYGVGKAWYFLFTRNYW---RAKENISLAHDINNSAQLIIDYDSEGNFENEYTDLRVGISIRNLVKTY 2346
            TEN T S  ++ Q + ++ CG  E              ++F   +   +    + V    N  + + N    +  RN E    +  I+  +   + GKI ++P+SP T++I+   N TF+ L  +R     W    R  +   + NS   NE+   ++         +F   L  T   V  V++F +  S              + N+       + + + C  L+K  P++   T E  + + M     +  +A +V  D      PSN++ L    +Y+IR+  + ++ T   K+ D +W   PR +   D +Y   GF  LQ+ ++ + I  VT ++    G  +Q MPYPCYVDD+F+R ++  MP  + +AW+ SV  +IK +VYEKE RLKE MR+MGL N + W  WF+S+++ L+    ++ LLL   ++L +S   VVFL L  + V  I Q F+IS  F+ ANLA+  GG+IYF LY+P+V+ +  Q  +      +  L + VAF     +   +E+   G  + NLF   + +  + +  C++++  D+ LY  + WY+E+VFPGQYG+ + WYF FT++YW    +  N ++    +N+  + I        E E T L++G+ I NLVK Y
Sbjct:  293 TENATGSPSLMYQAVSRIVCGHPEGGGLKIKSLNWYEDSNFQALFGNHNDSDDQPVPVYDNTTTPYCN----SMMRNMEASPISRMIWRALKPLLMGKILYTPHSPATQKIIHEVNKTFQELGILRDLGGMWE-EARPKVWNFMENS---NEMDLMRTLLLNNLTANFFSAQLAGTQWSVEDVISFLSKHSEDTRPQGTAFTWRDVFNETDQAIMSISRFMECVNLDKLEPVS---TEEKLVNESMSLLDNRKFWAGIVFLDI-----PSNSSELPPNVNYKIRMDIDNVERTN--KIKDGYWDPGPRADPFEDLRYIWGGFSYLQDVVEHSIIRAVTGSKE-KTGVYIQQMPYPCYVDDIFLRIMSRSMPLFMTLAWMYSVAIIIKGVVYEKEARLKETMRIMGLDNGILWFSWFISSLIPLLISAGLLVLLLKMGNLLPYSDPGVVFLFLGSFAVVTIMQCFLISTAFARANLAAACGGIIYFTLYLPYVLCVAWQDYVGFAAKVIASLLSPVAFGFGCEYFALFEEQGVGIQWNNLFSSPVEEDDYNLTTCLILMYFDAFLYGVMTWYIETVFPGQYGIPRPWYFPFTKSYWFGENSTNNTAIHGKKSNAGAVCI--------EEEPTHLKLGVYIENLVKVY 911          
BLAST of ATP binding cassette subfamily A member 1 vs. Ensembl Zebrafish
Match: abca1b (ATP-binding cassette, sub-family A (ABC1), member 1B [Source:ZFIN;Acc:ZDB-GENE-030131-9826])

HSP 1 Score: 254.603 bits (649), Expect = 1.294e-70
Identity = 192/646 (29.72%), Postives = 320/646 (49.54%), Query Frame = 1
Query:  559 TENLTASKPIIIQ-IFKVFCGSDE--------------NDFTEFYYKFSSISTKNVSGQTNAGSQFMNESNVTCERNFENFFGNSNIFDTISSWVFGKIYFSPNSPLTREIMRRANITFETLDYIRLASIEWRLHFRDWINEAVNNSKLINELKSCKSWYF------YFDNNLCET---VNAVLNFQTIQS--------------ILNKISLMFSLLEKTLNCTELNKFMPINESITVENFIKQPM-----KSVFAVLVINDTFRYLTPSNATFL----SYQIRIPENQIDSTKHFKVTDKFWTAEPRRETLRDFKYYTSGFLLLQEAIDRAFIEIVTNNETIDVGSSMQIMPYPCYVDDMFIRFITNMMPFMLVIAWVPSVTGLIKSIVYEKERRLKEFMRVMGLGNSVHWIGWFLSTVVVLIFPVTIMXXXXXXXXXXXXXXXXXXXXXXXXXXXXXICQVFMISLFFSNANLASVAGGVIYFILYMPFVVFIRMQSDLSTGFYYLGGLSAQVAFCNAINFIGYWEQSTEGAHFGNLFDGAIIDLKFGVGHCMLMLIVDSVLYLSVAWYVESVFPGQYGVGKAWYFLFTRNYW---RAKENISLAHDINNSAQLIIDYDSEGNFENEYTDLRVGISIRNLVKTY 2346
            TEN T S  ++ Q + ++ CG  E              ++F   +   +    + V    N  + + N    +  RN E    +  I+  +   + GKI ++P+SP T++I+   N TF+ L  +R     W    R  +   + NS   NE+   ++         +F   L  T   V  V++F +  S              + N+       + + + C  L+K  P++   T E  + + M     +  +A +V  D      PSN++ L    +Y+IR+  + ++ T   K+ D +W   PR +   D +Y   GF  LQ+ ++ + I  VT ++    G  +Q MPYPCYVDD+F+R ++  MP  + +AW+ SV  +IK +VYEKE RLKE MR+MGL N + W  WF+S+++ L+    ++ LLL   ++L +S   VVFL L  + V  I Q F+IS  F+ ANLA+  GG+IYF LY+P+V+ +  Q  +      +  L + VAF     +   +E+   G  + NLF   + +  + +  C++++  D+ LY  + WY+E+VFPGQYG+ + WYF FT++YW    +  N ++    +N+  + I        E E T L++G+ I NLVK Y
Sbjct:  293 TENATGSPSLMYQAVSRIVCGHPEGGGLKIKSLNWYEDSNFQALFGNHNDSDDQPVPVYDNTTTPYCN----SMMRNMEASPISRMIWRALKPLLMGKILYTPHSPATQKIIHEVNKTFQELGILRDLGGMWE-EARPKVWNFMENS---NEMDLMRTLLLNNLTANFFSAQLAGTQWSVEDVISFLSKHSEDTRPQGTAFTWRDVFNETDQAIMSISRFMECVNLDKLEPVS---TEEKLVNESMSLLDNRKFWAGIVFLDI-----PSNSSELPPNVNYKIRMDIDNVERTN--KIKDGYWDPGPRADPFEDLRYIWGGFSYLQDVVEHSIIRAVTGSKE-KTGVYIQQMPYPCYVDDIFLRIMSRSMPLFMTLAWMYSVAIIIKGVVYEKEARLKETMRIMGLDNGILWFSWFISSLIPLLISAGLLVLLLKMGNLLPYSDPGVVFLFLGSFAVVTIMQCFLISTAFARANLAAACGGIIYFTLYLPYVLCVAWQDYVGFAAKVIASLLSPVAFGFGCEYFALFEEQGVGIQWNNLFSSPVEEDDYNLTTCLILMYFDAFLYGVMTWYIETVFPGQYGIPRPWYFPFTKSYWFGENSTNNTAIHGKKSNAGAVCI--------EEEPTHLKLGVYIENLVKVY 911          
BLAST of ATP binding cassette subfamily A member 1 vs. Ensembl Zebrafish
Match: abca1a (ATP-binding cassette, sub-family A (ABC1), member 1A [Source:ZFIN;Acc:ZDB-GENE-031006-12])

HSP 1 Score: 254.603 bits (649), Expect = 1.406e-70
Identity = 166/549 (30.24%), Postives = 279/549 (50.82%), Query Frame = 1
Query:  772 IFDTISSWVFGKIYFSPNSPLTREIMRRANITFETLDYIRLASIEWRLHFRDWINEAVNNSK---LINELKSCKSWYFYFDNNLCET---VNAVLNFQTIQS--------------ILNKISLMFSLLEKTLNCTELNKFMPI-NESITVENFIKQPMKSVFAVLVINDTFRYLTPSNATFLSYQIRIPENQIDSTKHFKVTDKFWTAEPRRETLRDFKYYTSGFLLLQEAIDRAFIEIVTNNETIDVGSSMQIMPYPCYVDDMFIRFITNMMPFMLVIAWVPSVTGLIKSIVYEKERRLKEFMRVMGLGNSVHWIGWFLSTVVVLIFPVTIMXXXXXXXXXXXXXXXXXXXXXXXXXXXXXICQVFMISLFFSNANLASVAGGVIYFILYMPFVVFIRMQSDLSTGFYYLGGLSAQVAFCNAINFIGYWEQSTEGAHFGNLFDGAIIDLKFGVGHCMLMLIVDSVLYLSVAWYVESVFPGQYGVGKAWYFLFTRNYWRAKE---NISLAHDINNSAQLIIDYDSEGNFENEYTDLRVGISIRNLVKTY 2346
            I+  +   + GKI ++P++P T+ I+   N TF+ L  +R     W    R  I   + NS+   L+  L    +   +F+  L  T   V  V  F +  S              + N+       + + + C  L+K  P+ NE   V   ++      F   ++    +  T      ++Y+IR+  + ++ T   K+ D +W   PR +   D +Y   GF  LQ+ I+   I  +T ++    G  +Q MPYPCYVDD+F+R ++  MP  + +AW+ SV  +IK +VYEKE RLKE MR+MGL N + W+ WF+S+++ L+    ++ L+L   ++L +S   V++L L  + V  I Q F+IS  FS ANLA+  GG+IYF LY+P+V+ +  Q+ +  G   +  L + VAF     +   +E+   G  + NL    + +  + +   + +++ DSVLY  + WY+E+VFPGQYG+ + WYF FT++YW  ++     S+  +   +A+ +         E E   +  G+ I NL+K Y
Sbjct:  376 IWRALKPLLMGKILYTPDTPATQRIIHEVNKTFQELGVLRDLGGMWE-EMRPKIWNFMENSEEMDLVRTLLQNNASARFFNAKLSGTEWRVEDVSRFLSKSSEDTRPHGTAYTWREVFNETDQAIQTISRFMECVNLDKLEPVANEERLVNKSMRLLDDRKFWAGIVFPDMQSNTSDLPLNVNYKIRMDIDNVERTN--KIKDGYWDPGPRADPFEDLRYIWGGFTYLQDVIEHGIIRALTGSKE-KTGVYIQQMPYPCYVDDIFLRVMSRSMPLFMTLAWMYSVAIIIKGVVYEKEARLKETMRIMGLDNGILWLSWFISSLIPLLISAALLVLILKMGNLLPYSDPGVIYLFLSSFAVVTIMQCFLISTLFSRANLAAACGGIIYFTLYLPYVLCVAWQNYVGFGAKIVVSLLSPVAFGFGCEYFALFEEQGVGIQWSNLLSSPMQEDSYNLTTSICLMLFDSVLYAVMTWYIEAVFPGQYGIPRPWYFPFTKSYWCGEKCGWTTSVPSNRKENAEAVC-------IEEEPAHIDPGVYIENLMKIY 913          
BLAST of ATP binding cassette subfamily A member 1 vs. Ensembl Zebrafish
Match: abca1a (ATP-binding cassette, sub-family A (ABC1), member 1A [Source:ZFIN;Acc:ZDB-GENE-031006-12])

HSP 1 Score: 254.603 bits (649), Expect = 1.406e-70
Identity = 166/549 (30.24%), Postives = 279/549 (50.82%), Query Frame = 1
Query:  772 IFDTISSWVFGKIYFSPNSPLTREIMRRANITFETLDYIRLASIEWRLHFRDWINEAVNNSK---LINELKSCKSWYFYFDNNLCET---VNAVLNFQTIQS--------------ILNKISLMFSLLEKTLNCTELNKFMPI-NESITVENFIKQPMKSVFAVLVINDTFRYLTPSNATFLSYQIRIPENQIDSTKHFKVTDKFWTAEPRRETLRDFKYYTSGFLLLQEAIDRAFIEIVTNNETIDVGSSMQIMPYPCYVDDMFIRFITNMMPFMLVIAWVPSVTGLIKSIVYEKERRLKEFMRVMGLGNSVHWIGWFLSTVVVLIFPVTIMXXXXXXXXXXXXXXXXXXXXXXXXXXXXXICQVFMISLFFSNANLASVAGGVIYFILYMPFVVFIRMQSDLSTGFYYLGGLSAQVAFCNAINFIGYWEQSTEGAHFGNLFDGAIIDLKFGVGHCMLMLIVDSVLYLSVAWYVESVFPGQYGVGKAWYFLFTRNYWRAKE---NISLAHDINNSAQLIIDYDSEGNFENEYTDLRVGISIRNLVKTY 2346
            I+  +   + GKI ++P++P T+ I+   N TF+ L  +R     W    R  I   + NS+   L+  L    +   +F+  L  T   V  V  F +  S              + N+       + + + C  L+K  P+ NE   V   ++      F   ++    +  T      ++Y+IR+  + ++ T   K+ D +W   PR +   D +Y   GF  LQ+ I+   I  +T ++    G  +Q MPYPCYVDD+F+R ++  MP  + +AW+ SV  +IK +VYEKE RLKE MR+MGL N + W+ WF+S+++ L+    ++ L+L   ++L +S   V++L L  + V  I Q F+IS  FS ANLA+  GG+IYF LY+P+V+ +  Q+ +  G   +  L + VAF     +   +E+   G  + NL    + +  + +   + +++ DSVLY  + WY+E+VFPGQYG+ + WYF FT++YW  ++     S+  +   +A+ +         E E   +  G+ I NL+K Y
Sbjct:  376 IWRALKPLLMGKILYTPDTPATQRIIHEVNKTFQELGVLRDLGGMWE-EMRPKIWNFMENSEEMDLVRTLLQNNASARFFNAKLSGTEWRVEDVSRFLSKSSEDTRPHGTAYTWREVFNETDQAIQTISRFMECVNLDKLEPVANEERLVNKSMRLLDDRKFWAGIVFPDMQSNTSDLPLNVNYKIRMDIDNVERTN--KIKDGYWDPGPRADPFEDLRYIWGGFTYLQDVIEHGIIRALTGSKE-KTGVYIQQMPYPCYVDDIFLRVMSRSMPLFMTLAWMYSVAIIIKGVVYEKEARLKETMRIMGLDNGILWLSWFISSLIPLLISAALLVLILKMGNLLPYSDPGVIYLFLSSFAVVTIMQCFLISTLFSRANLAAACGGIIYFTLYLPYVLCVAWQNYVGFGAKIVVSLLSPVAFGFGCEYFALFEEQGVGIQWSNLLSSPMQEDSYNLTTSICLMLFDSVLYAVMTWYIEAVFPGQYGIPRPWYFPFTKSYWCGEKCGWTTSVPSNRKENAEAVC-------IEEEPAHIDPGVYIENLMKIY 913          
BLAST of ATP binding cassette subfamily A member 1 vs. Ensembl Zebrafish
Match: zgc:172302 (zgc:172302 [Source:ZFIN;Acc:ZDB-GENE-081205-5])

HSP 1 Score: 251.521 bits (641), Expect = 4.930e-70
Identity = 181/621 (29.15%), Postives = 302/621 (48.63%), Query Frame = 1
Query:  604 KVFCGSDENDFTEF----YYKFSSIST---KNVSGQTNAGSQFMNESNVTCERNFENFFGNSN---IFDTISSWVFGKIYFSPNSPLTREIMRRANITFETLDYIRLASIEWR---LHFRDWINEAVNNSKLINELKSCKSWYFYFD---NNLCETVNAVLNFQTIQS---------------ILNKISLMFSLLEKTLNCTELNKFMPINESITVEN-FIKQPMK--------SVFAVLVINDTFRYLTPSNATFLSYQIRIPENQIDSTKHFKVTDKFWTAEPRRETLRDFKYYTSGFLLLQEAIDRAFIEIVTNNETIDVGSSMQIMPYPCYVDDMFIRFITNMMPFMLVIAWVPSVTGLIKSIVYEKERRLKEFMRVMGLGNSVHWIGWFLSTVVVLIFPVTIMXXXXXXXXXXXXXXXXXXXXXXXXXXXXXICQVFMISLFFSNANLASVAGGVIYFILYMPFVVFIRMQSDLSTGFYYLGGLSAQVAFCNAINFIGYWEQSTEGAHFGNLFDGAIIDLKFGVGHCMLMLIVDSVLYLSVAWYVESVFPGQYGVGKAWYFLFTRNYWRAKENISLAHDINNSAQLIIDYDSEGNFENEYTDLRVGISIRNLVKTY 2346
            ++ CG  E          +Y+   I +   +N S +T+  +   N +   CE   +N   N     ++  I     GK+ ++P++P+TR IM   N TF+  + ++     W+      + ++  +V   +L+ +L          +    N   T + +  F + Q                +   ++  F+ L +   C  LNK     E +T E   +++ ++        +    L+ N +   L P     + Y+IR+  +  D T+  K+ DKFW   P  E   D +Y   GF+ +Q+ ++RA   ++T  E    G  +Q MPYPC+VDD+FIR +   +P  + +AW+ SV  +IK +VYEKE RLKE MR+MGLG+ + W  WF+S+ +  +F   ++   L +  IL +S  AVVF  L  +  + I   F+IS FFS ANLA+  GG+IYF LY+P+V+ +  +  L++    L    + VAF     +   +E+   G  + NL    +    +     ++ML  D+++Y    WY+E+VFPGQYG+ + WYF+F  NYW     + L   I  + +     + +   E E T+L +G+SIRNLVK Y
Sbjct:  315 RIMCGHPEAGGERIPSFNWYEDQDIKSFLGRNASEETSLEND--NSTTSFCENLIQNLESNPLSRIVWRGIKPLFIGKLLYTPDTPITRTIMSEVNKTFQDFEILKDVHEAWQEVGPRIKTFMESSVE-IRLLQDLLRRPEVAVIVNMRLENTSWTASRIARFLSTQDPDTPRKDGAQLTWFDLYQDLNNTFTTLSELTKCFSLNKL----EGLTTEGEMVERALELLEDRQFWAGIVFLLPNSSSSVLPP----HVKYKIRMDID--DVTRTNKIKDKFWDPGPAAEPFSDMRYVWGGFVYVQDLVERAVTRLLTGKEA-KTGIYVQQMPYPCFVDDVFIRVLNRSLPLFMTLAWIYSVAMIIKGVVYEKEARLKETMRIMGLGSGMLWFSWFISSYLPFLFSAALLIAALKWGDILPYSDPAVVFFFLAAFATATIMLCFLISTFFSRANLAAACGGLIYFTLYLPYVLCVAWREYLTSTHRILASFLSPVAFGFGCEYFSQYEEQGVGIQWFNLKSSPMEGDTYSFNTSIMMLYADALIYALATWYIEAVFPGQYGIPRPWYFIFQLNYW-GGVPLELGLPIPPAPR----EEQDARIEAEPTNLILGVSIRNLVKIY 916          
BLAST of ATP binding cassette subfamily A member 1 vs. Ensembl Xenopus
Match: ABCA1 (ATP binding cassette subfamily A member 1 [Source:NCBI gene;Acc:100491942])

HSP 1 Score: 265.388 bits (677), Expect = 3.759e-74
Identity = 195/640 (30.47%), Postives = 316/640 (49.38%), Query Frame = 1
Query:  565 NLTASKPIIIQ-IFKVFCGSDENDFTEF----YYKFSSISTKNVSGQ----TNAGSQFMNESNVT--CE---RNFENFFGNSNIFDTISSWVFGKIYFSPNSPLTREIMRRANITFETLDYIRLASIEW---RLHFRDWINEAVNNSKLINELKSCKSWYFYFDNNL------CETVNAVLNFQTI------------QSILNKISLMFSLLEKTLNCTELNKFMPINESITVENFIKQPM-----KSVFAVLVINDTFRYLTPSNATFL----SYQIRIPENQIDSTKHFKVTDKFWTAEPRRETLRDFKYYTSGFLLLQEAIDRAFIEIVTNNETIDVGSSMQIMPYPCYVDDMFIRFITNMMPFMLVIAWVPSVTGLIKSIVYEKERRLKEFMRVMGLGNSVHWIGWFLSTVVVLIFPVTIMXXXXXXXXXXXXXXXXXXXXXXXXXXXXXICQVFMISLFFSNANLASVAGGVIYFILYMPFVVFIRMQSDLSTGFYYLGGLSAQVAFCNAINFIGYWEQSTEGAHFGNLFDGAIIDLKFGVGHCMLMLIVDSVLYLSVAWYVESVFPGQYGVGKAWYFLFTRNYWRAKENISLAHDINNSAQLIIDYDSEGNF--ENEYTDLRVGISIRNLVKTY 2346
            N TAS   + Q + ++ CG  E    +     +Y+ ++       G+    T+  SQ   +++ T  C    +N E+      I+  +   + GKI ++P++P T+ +M   N TF+ L   R     W   R   ++++ E+     LI  L + K    + D  L       E ++  L  +T             +  LN+   +   L + + C  L+K  P+    T E  I + M     +  +A +V  D      P   T L     Y+IR+  + ++ T   K+ D +W   PR +   D +Y   GF  LQ+ +++A I + T  E    G  +Q MPYPCYVDD+F+R ++  MP  + +AW+ SV  +IK IVYEKE RLKE MR+MGL N + W+ WF+S+++ L+    ++ L+L   ++L +S  +VVF+ L ++ V  I Q F+IS  FS ANLA+  GG+IYF LY+P+V+ +  Q  +           + VAF          E+   G  + NL +  + +  + +     M++ D++LY  + WY+E+VFPGQYG+ + WYF FT++YW  +E         N    +    SEG F  E E + L +G+SI+NLVK Y
Sbjct:  241 NATASPSTLYQAVSRIVCGHPEGGGLKIKSLNWYEDNNYKALFGGGEGDNSTDEDSQVAYDNSTTPYCNDLMQNLESSPLYRMIWRALKPLLVGKILYTPSTPATQMLMSEVNKTFQELSVFRDLGAMWEEVRPQIKNFM-ESSQEMDLIRTLLTNKGSKTFLDQQLNSTGWTTENISRFLAKETADVETENGPFYSWREALNETDRVVLTLSRFMECVNLDKLEPV---ATEEMLIDKSMELLNERKFWAGIVFMDM-----PEEETELPHHVKYKIRMDIDNVERTN--KIKDGYWDPGPRADPFEDMRYIWGGFSYLQDVVEQAIIRVQTGVEK-RTGIYVQQMPYPCYVDDIFLRVMSRSMPLFMTLAWIYSVAVIIKGIVYEKEARLKETMRIMGLDNGILWLSWFISSLIPLLMSAALLVLILKTGNLLPYSDPSVVFVFLSVFAVVTISQCFLISTIFSRANLAAACGGIIYFTLYLPYVLCVAWQDYVGYTLKIFASFLSPVAFGFGCEVFALLEEQGVGVQWDNLLESPLEENGYNITTSGFMMLFDTLLYGIMTWYIEAVFPGQYGIPRPWYFPFTKSYWCGEECKEY-----NQPHTVQKGSSEGMFCMEEEPSHLPLGVSIQNLVKIY 863          
BLAST of ATP binding cassette subfamily A member 1 vs. Ensembl Xenopus
Match: ABCA1 (ATP binding cassette subfamily A member 1 [Source:NCBI gene;Acc:100491942])

HSP 1 Score: 265.003 bits (676), Expect = 5.983e-74
Identity = 193/638 (30.25%), Postives = 314/638 (49.22%), Query Frame = 1
Query:  565 NLTASKPIIIQ-IFKVFCGSDENDFTEF----YYKFSSISTKNVSGQ----TNAGSQFMNESNVT--CE---RNFENFFGNSNIFDTISSWVFGKIYFSPNSPLTREIMRRANITFETLDYIRLASIEW---RLHFRDWINEAVNNSKLINELKSCKSWYFYFDNNL------CETVNAVLNFQTI------------QSILNKISLMFSLLEKTLNCTELNKFMPINESITVENFIKQPM-----KSVFAVLVINDTFRYLTPSNATFL----SYQIRIPENQIDSTKHFKVTDKFWTAEPRRETLRDFKYYTSGFLLLQEAIDRAFIEIVTNNETIDVGSSMQIMPYPCYVDDMFIRFITNMMPFMLVIAWVPSVTGLIKSIVYEKERRLKEFMRVMGLGNSVHWIGWFLSTVVVLIFPVTIMXXXXXXXXXXXXXXXXXXXXXXXXXXXXXICQVFMISLFFSNANLASVAGGVIYFILYMPFVVFIRMQSDLSTGFYYLGGLSAQVAFCNAINFIGYWEQSTEGAHFGNLFDGAIIDLKFGVGHCMLMLIVDSVLYLSVAWYVESVFPGQYGVGKAWYFLFTRNYWRAKENISLAHDINNSAQLIIDYDSEGNFENEYTDLRVGISIRNLVKTY 2346
            N TAS   + Q + ++ CG  E    +     +Y+ ++       G+    T+  SQ   +++ T  C    +N E+      I+  +   + GKI ++P++P T+ +M   N TF+ L   R     W   R   ++++ E+     LI  L + K    + D  L       E ++  L  +T             +  LN+   +   L + + C  L+K  P+    T E  I + M     +  +A +V  D      P   T L     Y+IR+  + ++ T   K+ D +W   PR +   D +Y   GF  LQ+ +++A I + T  E    G  +Q MPYPCYVDD+F+R ++  MP  + +AW+ SV  +IK IVYEKE RLKE MR+MGL N + W+ WF+S+++ L+    ++ L+L   ++L +S  +VVF+ L ++ V  I Q F+IS  FS ANLA+  GG+IYF LY+P+V+ +  Q  +           + VAF          E+   G  + NL +  + +  + +     M++ D++LY  + WY+E+VFPGQYG+ + WYF FT++YW  +E         N    +    SE   E E + L +G+SI+NLVK Y
Sbjct:  290 NATASPSTLYQAVSRIVCGHPEGGGLKIKSLNWYEDNNYKALFGGGEGDNSTDEDSQVAYDNSTTPYCNDLMQNLESSPLYRMIWRALKPLLVGKILYTPSTPATQMLMSEVNKTFQELSVFRDLGAMWEEVRPQIKNFM-ESSQEMDLIRTLLTNKGSKTFLDQQLNSTGWTTENISRFLAKETADVETENGPFYSWREALNETDRVVLTLSRFMECVNLDKLEPV---ATEEMLIDKSMELLNERKFWAGIVFMDM-----PEEETELPHHVKYKIRMDIDNVERTN--KIKDGYWDPGPRADPFEDMRYIWGGFSYLQDVVEQAIIRVQTGVEK-RTGIYVQQMPYPCYVDDIFLRVMSRSMPLFMTLAWIYSVAVIIKGIVYEKEARLKETMRIMGLDNGILWLSWFISSLIPLLMSAALLVLILKTGNLLPYSDPSVVFVFLSVFAVVTISQCFLISTIFSRANLAAACGGIIYFTLYLPYVLCVAWQDYVGYTLKIFASFLSPVAFGFGCEVFALLEEQGVGVQWDNLLESPLEENGYNITTSGFMMLFDTLLYGIMTWYIEAVFPGQYGIPRPWYFPFTKSYWCGEECKEY-----NQPHTVQKGSSEVCMEEEPSHLPLGVSIQNLVKIY 910          
BLAST of ATP binding cassette subfamily A member 1 vs. Ensembl Xenopus
Match: ABCA1 (ATP binding cassette subfamily A member 1 [Source:NCBI gene;Acc:100491942])

HSP 1 Score: 264.618 bits (675), Expect = 8.679e-74
Identity = 193/638 (30.25%), Postives = 314/638 (49.22%), Query Frame = 1
Query:  565 NLTASKPIIIQ-IFKVFCGSDENDFTEF----YYKFSSISTKNVSGQ----TNAGSQFMNESNVT--CE---RNFENFFGNSNIFDTISSWVFGKIYFSPNSPLTREIMRRANITFETLDYIRLASIEW---RLHFRDWINEAVNNSKLINELKSCKSWYFYFDNNL------CETVNAVLNFQTI------------QSILNKISLMFSLLEKTLNCTELNKFMPINESITVENFIKQPM-----KSVFAVLVINDTFRYLTPSNATFL----SYQIRIPENQIDSTKHFKVTDKFWTAEPRRETLRDFKYYTSGFLLLQEAIDRAFIEIVTNNETIDVGSSMQIMPYPCYVDDMFIRFITNMMPFMLVIAWVPSVTGLIKSIVYEKERRLKEFMRVMGLGNSVHWIGWFLSTVVVLIFPVTIMXXXXXXXXXXXXXXXXXXXXXXXXXXXXXICQVFMISLFFSNANLASVAGGVIYFILYMPFVVFIRMQSDLSTGFYYLGGLSAQVAFCNAINFIGYWEQSTEGAHFGNLFDGAIIDLKFGVGHCMLMLIVDSVLYLSVAWYVESVFPGQYGVGKAWYFLFTRNYWRAKENISLAHDINNSAQLIIDYDSEGNFENEYTDLRVGISIRNLVKTY 2346
            N TAS   + Q + ++ CG  E    +     +Y+ ++       G+    T+  SQ   +++ T  C    +N E+      I+  +   + GKI ++P++P T+ +M   N TF+ L   R     W   R   ++++ E+     LI  L + K    + D  L       E ++  L  +T             +  LN+   +   L + + C  L+K  P+    T E  I + M     +  +A +V  D      P   T L     Y+IR+  + ++ T   K+ D +W   PR +   D +Y   GF  LQ+ +++A I + T  E    G  +Q MPYPCYVDD+F+R ++  MP  + +AW+ SV  +IK IVYEKE RLKE MR+MGL N + W+ WF+S+++ L+    ++ L+L   ++L +S  +VVF+ L ++ V  I Q F+IS  FS ANLA+  GG+IYF LY+P+V+ +  Q  +           + VAF          E+   G  + NL +  + +  + +     M++ D++LY  + WY+E+VFPGQYG+ + WYF FT++YW  +E         N    +    SE   E E + L +G+SI+NLVK Y
Sbjct:  288 NATASPSTLYQAVSRIVCGHPEGGGLKIKSLNWYEDNNYKALFGGGEGDNSTDEDSQVAYDNSTTPYCNDLMQNLESSPLYRMIWRALKPLLVGKILYTPSTPATQMLMSEVNKTFQELSVFRDLGAMWEEVRPQIKNFM-ESSQEMDLIRTLLTNKGSKTFLDQQLNSTGWTTENISRFLAKETADVETENGPFYSWREALNETDRVVLTLSRFMECVNLDKLEPV---ATEEMLIDKSMELLNERKFWAGIVFMDM-----PEEETELPHHVKYKIRMDIDNVERTN--KIKDGYWDPGPRADPFEDMRYIWGGFSYLQDVVEQAIIRVQTGVEK-RTGIYVQQMPYPCYVDDIFLRVMSRSMPLFMTLAWIYSVAVIIKGIVYEKEARLKETMRIMGLDNGILWLSWFISSLIPLLMSAALLVLILKTGNLLPYSDPSVVFVFLSVFAVVTISQCFLISTIFSRANLAAACGGIIYFTLYLPYVLCVAWQDYVGYTLKIFASFLSPVAFGFGCEVFALLEEQGVGVQWDNLLESPLEENGYNITTSGFMMLFDTLLYGIMTWYIEAVFPGQYGIPRPWYFPFTKSYWCGEECKEY-----NQPHTVQKGSSEVCMEEEPSHLPLGVSIQNLVKIY 908          
BLAST of ATP binding cassette subfamily A member 1 vs. Ensembl Xenopus
Match: ABCA1 (ATP binding cassette subfamily A member 1 [Source:NCBI gene;Acc:100491942])

HSP 1 Score: 264.618 bits (675), Expect = 8.767e-74
Identity = 193/638 (30.25%), Postives = 314/638 (49.22%), Query Frame = 1
Query:  565 NLTASKPIIIQ-IFKVFCGSDENDFTEF----YYKFSSISTKNVSGQ----TNAGSQFMNESNVT--CE---RNFENFFGNSNIFDTISSWVFGKIYFSPNSPLTREIMRRANITFETLDYIRLASIEW---RLHFRDWINEAVNNSKLINELKSCKSWYFYFDNNL------CETVNAVLNFQTI------------QSILNKISLMFSLLEKTLNCTELNKFMPINESITVENFIKQPM-----KSVFAVLVINDTFRYLTPSNATFL----SYQIRIPENQIDSTKHFKVTDKFWTAEPRRETLRDFKYYTSGFLLLQEAIDRAFIEIVTNNETIDVGSSMQIMPYPCYVDDMFIRFITNMMPFMLVIAWVPSVTGLIKSIVYEKERRLKEFMRVMGLGNSVHWIGWFLSTVVVLIFPVTIMXXXXXXXXXXXXXXXXXXXXXXXXXXXXXICQVFMISLFFSNANLASVAGGVIYFILYMPFVVFIRMQSDLSTGFYYLGGLSAQVAFCNAINFIGYWEQSTEGAHFGNLFDGAIIDLKFGVGHCMLMLIVDSVLYLSVAWYVESVFPGQYGVGKAWYFLFTRNYWRAKENISLAHDINNSAQLIIDYDSEGNFENEYTDLRVGISIRNLVKTY 2346
            N TAS   + Q + ++ CG  E    +     +Y+ ++       G+    T+  SQ   +++ T  C    +N E+      I+  +   + GKI ++P++P T+ +M   N TF+ L   R     W   R   ++++ E+     LI  L + K    + D  L       E ++  L  +T             +  LN+   +   L + + C  L+K  P+    T E  I + M     +  +A +V  D      P   T L     Y+IR+  + ++ T   K+ D +W   PR +   D +Y   GF  LQ+ +++A I + T  E    G  +Q MPYPCYVDD+F+R ++  MP  + +AW+ SV  +IK IVYEKE RLKE MR+MGL N + W+ WF+S+++ L+    ++ L+L   ++L +S  +VVF+ L ++ V  I Q F+IS  FS ANLA+  GG+IYF LY+P+V+ +  Q  +           + VAF          E+   G  + NL +  + +  + +     M++ D++LY  + WY+E+VFPGQYG+ + WYF FT++YW  +E         N    +    SE   E E + L +G+SI+NLVK Y
Sbjct:  258 NATASPSTLYQAVSRIVCGHPEGGGLKIKSLNWYEDNNYKALFGGGEGDNSTDEDSQVAYDNSTTPYCNDLMQNLESSPLYRMIWRALKPLLVGKILYTPSTPATQMLMSEVNKTFQELSVFRDLGAMWEEVRPQIKNFM-ESSQEMDLIRTLLTNKGSKTFLDQQLNSTGWTTENISRFLAKETADVETENGPFYSWREALNETDRVVLTLSRFMECVNLDKLEPV---ATEEMLIDKSMELLNERKFWAGIVFMDM-----PEEETELPHHVKYKIRMDIDNVERTN--KIKDGYWDPGPRADPFEDMRYIWGGFSYLQDVVEQAIIRVQTGVEK-RTGIYVQQMPYPCYVDDIFLRVMSRSMPLFMTLAWIYSVAVIIKGIVYEKEARLKETMRIMGLDNGILWLSWFISSLIPLLMSAALLVLILKTGNLLPYSDPSVVFVFLSVFAVVTISQCFLISTIFSRANLAAACGGIIYFTLYLPYVLCVAWQDYVGYTLKIFASFLSPVAFGFGCEVFALLEEQGVGVQWDNLLESPLEENGYNITTSGFMMLFDTLLYGIMTWYIEAVFPGQYGIPRPWYFPFTKSYWCGEECKEY-----NQPHTVQKGSSEVCMEEEPSHLPLGVSIQNLVKIY 878          
BLAST of ATP binding cassette subfamily A member 1 vs. Ensembl Xenopus
Match: ABCA1 (ATP binding cassette subfamily A member 1 [Source:NCBI gene;Acc:100491942])

HSP 1 Score: 264.618 bits (675), Expect = 8.790e-74
Identity = 193/638 (30.25%), Postives = 314/638 (49.22%), Query Frame = 1
Query:  565 NLTASKPIIIQ-IFKVFCGSDENDFTEF----YYKFSSISTKNVSGQ----TNAGSQFMNESNVT--CE---RNFENFFGNSNIFDTISSWVFGKIYFSPNSPLTREIMRRANITFETLDYIRLASIEW---RLHFRDWINEAVNNSKLINELKSCKSWYFYFDNNL------CETVNAVLNFQTI------------QSILNKISLMFSLLEKTLNCTELNKFMPINESITVENFIKQPM-----KSVFAVLVINDTFRYLTPSNATFL----SYQIRIPENQIDSTKHFKVTDKFWTAEPRRETLRDFKYYTSGFLLLQEAIDRAFIEIVTNNETIDVGSSMQIMPYPCYVDDMFIRFITNMMPFMLVIAWVPSVTGLIKSIVYEKERRLKEFMRVMGLGNSVHWIGWFLSTVVVLIFPVTIMXXXXXXXXXXXXXXXXXXXXXXXXXXXXXICQVFMISLFFSNANLASVAGGVIYFILYMPFVVFIRMQSDLSTGFYYLGGLSAQVAFCNAINFIGYWEQSTEGAHFGNLFDGAIIDLKFGVGHCMLMLIVDSVLYLSVAWYVESVFPGQYGVGKAWYFLFTRNYWRAKENISLAHDINNSAQLIIDYDSEGNFENEYTDLRVGISIRNLVKTY 2346
            N TAS   + Q + ++ CG  E    +     +Y+ ++       G+    T+  SQ   +++ T  C    +N E+      I+  +   + GKI ++P++P T+ +M   N TF+ L   R     W   R   ++++ E+     LI  L + K    + D  L       E ++  L  +T             +  LN+   +   L + + C  L+K  P+    T E  I + M     +  +A +V  D      P   T L     Y+IR+  + ++ T   K+ D +W   PR +   D +Y   GF  LQ+ +++A I + T  E    G  +Q MPYPCYVDD+F+R ++  MP  + +AW+ SV  +IK IVYEKE RLKE MR+MGL N + W+ WF+S+++ L+    ++ L+L   ++L +S  +VVF+ L ++ V  I Q F+IS  FS ANLA+  GG+IYF LY+P+V+ +  Q  +           + VAF          E+   G  + NL +  + +  + +     M++ D++LY  + WY+E+VFPGQYG+ + WYF FT++YW  +E         N    +    SE   E E + L +G+SI+NLVK Y
Sbjct:  292 NATASPSTLYQAVSRIVCGHPEGGGLKIKSLNWYEDNNYKALFGGGEGDNSTDEDSQVAYDNSTTPYCNDLMQNLESSPLYRMIWRALKPLLVGKILYTPSTPATQMLMSEVNKTFQELSVFRDLGAMWEEVRPQIKNFM-ESSQEMDLIRTLLTNKGSKTFLDQQLNSTGWTTENISRFLAKETADVETENGPFYSWREALNETDRVVLTLSRFMECVNLDKLEPV---ATEEMLIDKSMELLNERKFWAGIVFMDM-----PEEETELPHHVKYKIRMDIDNVERTN--KIKDGYWDPGPRADPFEDMRYIWGGFSYLQDVVEQAIIRVQTGVEK-RTGIYVQQMPYPCYVDDIFLRVMSRSMPLFMTLAWIYSVAVIIKGIVYEKEARLKETMRIMGLDNGILWLSWFISSLIPLLMSAALLVLILKTGNLLPYSDPSVVFVFLSVFAVVTISQCFLISTIFSRANLAAACGGIIYFTLYLPYVLCVAWQDYVGYTLKIFASFLSPVAFGFGCEVFALLEEQGVGVQWDNLLESPLEENGYNITTSGFMMLFDTLLYGIMTWYIEAVFPGQYGIPRPWYFPFTKSYWCGEECKEY-----NQPHTVQKGSSEVCMEEEPSHLPLGVSIQNLVKIY 912          
BLAST of ATP binding cassette subfamily A member 1 vs. Ensembl Mouse
Match: Abca1 (ATP-binding cassette, sub-family A (ABC1), member 1 [Source:MGI Symbol;Acc:MGI:99607])

HSP 1 Score: 272.322 bits (695), Expect = 1.557e-76
Identity = 179/561 (31.91%), Postives = 296/561 (52.76%), Query Frame = 1
Query:  739 RNFENFFGNSNIFDTISSWVFGKIYFSPNSPLTREIMRRANITFETLDYIRLASIEWR-LHFRDWI-NEAVNNSKLINELKSCKSWYFYFDNNL------CETVNAVL--NFQTIQS----------ILNKISLMFSLLEKTLNCTELNKFMPINESITVENFIKQPM--KSVFAVLVINDTFRYLTPSNATF---LSYQIRIPENQIDSTKHFKVTDKFWTAEPRRETLRDFKYYTSGFLLLQEAIDRAFIEIVTNNETIDVGSSMQIMPYPCYVDDMFIRFITNMMPFMLVIAWVPSVTGLIKSIVYEKERRLKEFMRVMGLGNSVHWIGWFLSTVVVLIFPVTIMXXXXXXXXXXXXXXXXXXXXXXXXXXXXXICQVFMISLFFSNANLASVAGGVIYFILYMPFVVFIRMQSDLSTGFYYLGGLSAQVAFCNAINFIGYWEQSTEGAHFGNLFDGAIIDLKFGVGHCMLMLIVDSVLYLSVAWYVESVFPGQYGVGKAWYFLFTRNYWRAKENISLAHDINNSAQLIIDYDSEGNFENEYTDLRVGISIRNLVKTY 2346
            +N E+   +  I+  +   + GKI ++P++P TR++M   N TF+ L         W  L  + W   E      L+  L   +    +++  L       + + A L  N + +QS            N+ +     + + + C  LNK  PI   + + N   + +  +  +A +V    F  +TP +      + Y+IR+  + ++ T   K+ D +W   PR +   D +Y   GF  LQ+ +++A I ++T +E    G  +Q MPYPCYVDD+F+R ++  MP  + +AW+ SV  +IKSIVYEKE RLKE MR+MGL N + W  WF+S+++ L+    ++ ++L   ++L +S  +VVF+ L ++ +  I Q F+IS  FS ANLA+  GG+IYF LY+P+V+ +  Q  +         L + VAF     +   +E+   G  + NLF+  + +  F +   + M++ D+ LY  + WY+E+VFPGQYG+ + WYF  T++YW  +E    +H    S+Q  +   SE   E E T LR+G+SI+NLVK Y
Sbjct:  360 KNLESSPLSRIIWKALKPLLVGKILYTPDTPATRQVMAEVNKTFQELAVFHDLEGMWEELSPQIWTFMENSQEMDLVRTLLDSRGNDQFWEQKLDGLDWTAQDIMAFLAKNPEDVQSPNGSVYTWREAFNETNQAIQTISRFMECVNLNKLEPIPTEVRLINKSMELLDERKFWAGIV----FTGITPDSVELPHHVKYKIRMDIDNVERTN--KIKDGYWDPGPRADPFEDMRYVWGGFAYLQDVVEQAIIRVLTGSEK-KTGVYVQQMPYPCYVDDIFLRVMSRSMPLFMTLAWIYSVAVIIKSIVYEKEARLKETMRIMGLDNGILWFSWFVSSLIPLLVSAGLLVVILKLGNLLPYSDPSVVFVFLSVFAMVTILQCFLISTLFSRANLAAACGGIIYFTLYLPYVLCVAWQDYVGFSIKIFASLLSPVAFGFGCEYFALFEEQGIGVQWDNLFESPVEEDGFNLTTAVSMMLFDTFLYGVMTWYIEAVFPGQYGIPRPWYFPCTKSYWFGEEIDEKSHP--GSSQKGV---SEICMEEEPTHLRLGVSIQNLVKVY 908          
BLAST of ATP binding cassette subfamily A member 1 vs. Ensembl Mouse
Match: Abca7 (ATP-binding cassette, sub-family A (ABC1), member 7 [Source:MGI Symbol;Acc:MGI:1351646])

HSP 1 Score: 223.787 bits (569), Expect = 2.066e-60
Identity = 162/548 (29.56%), Postives = 269/548 (49.09%), Query Frame = 1
Query:  784 ISSWVFGKIYFSPNSPLTREIMRRANITFETLDYIRLASIEWRL---HFRDWINEAVNNSKLINELKSCKSWYFYFDNNLCETVNAVLNFQTIQSILNK-------------ISLMFSLLEKTLNCTELNKF--MPINESITVENFIKQPMKSVFAVLVINDTFRYLTPS-------NATFLSYQIRIPENQIDSTKHFKVTDKFWTAEPRRETLRDFKYYTSGFLLLQEAIDRAFIEIVTNNETIDVGSSMQIMPYPCYVDDMFIRFITNMMPFMLVIAWVPSVTGLIKSIVYEKERRLKEFMRVMGLGNSVHWIGWFLSTVVVLIFPVTIMXXXXXXXXXXXXXXXXXXXXXXXXXXXXXICQVFMISLFFSNANLASVAGGVIYFILYMPFVVFIRMQSDLSTGFYYLGGLSAQVAFCNAINFIGYWEQSTEGAHFGNLFDGAIIDLKFGVGHCMLMLIVDSVLYLSVAWYVESVFPGQYGVGKAWYFLFTRNYWRAKENISLAHDINNSAQLIIDYDSEGNFENEYTDLRVGISIRNLVKTYPG 2352
            +   + GKI F+P++  TR++M + N TFE L  +R     W +      +++N++ N + L   L    +          +T  A    + I+  L+              +  +  +L + + C  L+K   +P  E++          + ++A +V       L PS       +   L ++IR+  +  D T+  K+ DKFW   P  +   D +Y   GF+ LQ+ +++A + ++    +   G  +Q MP+PCYVDD+F+R ++  +P  L +AW+ SV   +K++V EKE RL+E MR MGL  +V W+GWFLS +   +    ++ L+L   +IL +S   V+FL L  + V+ + Q F++S FFS ANLA+  GG+ YF LY+P+V+ +  +  L  G      L + VAF      +   E+  +GA + NL  G   D+ F +      L++D+V+Y    WY+E+V PGQYG+ + W F F R+YW             +S       D +   E     L  G+SIR L K + G
Sbjct:  284 LKPLILGKILFAPDTNFTRKLMAQVNQTFEELALLRDLHELWGVLGPQIFNFMNDSTNVAMLQRLLDVGGT------GQRQQTPRAQKKLEAIKDFLDPSRGGYSWREAHADMGRLAGILGQMMECVSLDKLEAVPSEEALVSRALELLGERRLWAGIVFLSPEHPLDPSELSSPALSPGHLRFKIRM--DIDDVTRTNKIRDKFWDPGPSADPFMDLRYVWGGFVYLQDLLEQAAVRVLGGGNS-RTGLYLQQMPHPCYVDDVFLRVLSRSLPLFLTLAWIYSVALTVKAVVREKETRLRETMRAMGLSRAVLWLGWFLSCLGPFLVSAALLVLVLKLGNILPYSHPVVIFLFLAAFAVATVAQSFLLSAFFSRANLAAACGGLAYFALYLPYVLCVAWRERLHLGGLLAASLLSPVAFGFGCESLALLEEQGDGAQWHNLGTGPAEDV-FSLAQVSAFLLLDAVIYGLALWYLEAVCPGQYGIPEPWNFPFRRSYWCGP------GPPKSSVLAPAPQDPKVLVEEPPLGLVPGVSIRGLKKHFRG 815          

HSP 2 Score: 52.7582 bits (125), Expect = 2.122e-6
Identity = 30/78 (38.46%), Postives = 46/78 (58.97%), Query Frame = 1
Query:   97 QLKVLLWKNFRLKKRKPITLISEXXXXXXXXXXXXXXRNSIFKFKMDHCEFKEKSMASMGFVPFILDFFCTFNTTCYN 330
            QL +LLWKN+  ++R+PI L+ E+L PL +  I+V VR+S    +   C F  K + S G VP++    C  N +C+ 
Sbjct:    6 QLMLLLWKNYTYRRRQPIQLLVELLWPLFLFFILVAVRHSHPPLEHHECHFPNKPLPSAGTVPWLQGLVCNVNNSCFQ 83          
BLAST of ATP binding cassette subfamily A member 1 vs. Ensembl Mouse
Match: Abca7 (ATP-binding cassette, sub-family A (ABC1), member 7 [Source:MGI Symbol;Acc:MGI:1351646])

HSP 1 Score: 223.787 bits (569), Expect = 2.281e-60
Identity = 162/552 (29.35%), Postives = 271/552 (49.09%), Query Frame = 1
Query:  772 IFDTISSWVFGKIYFSPNSPLTREIMRRANITFETLDYIRLASIEWRL---HFRDWINEAVNNSKLINELKSCKSWYFYFDNNLCETVNAVLNFQTIQSILNK-------------ISLMFSLLEKTLNCTELNKF--MPINESITVENFIKQPMKSVFAVLVINDTFRYLTPS-------NATFLSYQIRIPENQIDSTKHFKVTDKFWTAEPRRETLRDFKYYTSGFLLLQEAIDRAFIEIVTNNETIDVGSSMQIMPYPCYVDDMFIRFITNMMPFMLVIAWVPSVTGLIKSIVYEKERRLKEFMRVMGLGNSVHWIGWFLSTVVVLIFPVTIMXXXXXXXXXXXXXXXXXXXXXXXXXXXXXICQVFMISLFFSNANLASVAGGVIYFILYMPFVVFIRMQSDLSTGFYYLGGLSAQVAFCNAINFIGYWEQSTEGAHFGNLFDGAIIDLKFGVGHCMLMLIVDSVLYLSVAWYVESVFPGQYGVGKAWYFLFTRNYWRAKENISLAHDINNSAQLIIDYDSEGNFENEYTDLRVGISIRNLVKTYPG 2352
            ++  +   + GKI F+P++  TR++M + N TFE L  +R     W +      +++N++ N + L   L    +          +T  A    + I+  L+              +  +  +L + + C  L+K   +P  E++          + ++A +V       L PS       +   L ++IR+  +  D T+  K+ DKFW   P  +   D +Y   GF+ LQ+ +++A + ++    +   G  +Q MP+PCYVDD+F+R ++  +P  L +AW+ SV   +K++V EKE RL+E MR MGL  +V W+GWFLS +   +    ++ L+L   +IL +S   V+FL L  + V+ + Q F++S FFS ANLA+  GG+ YF LY+P+V+ +  +  L  G      L + VAF      +   E+  +GA + NL  G   D+ F +      L++D+V+Y    WY+E+V PGQYG+ + W F F R+YW             +S       D +   E     L  G+SIR L K + G
Sbjct:  280 LWRRLKPLILGKILFAPDTNFTRKLMAQVNQTFEELALLRDLHELWGVLGPQIFNFMNDSTNVAMLQRLLDVGGT------GQRQQTPRAQKKLEAIKDFLDPSRGGYSWREAHADMGRLAGILGQMMECVSLDKLEAVPSEEALVSRALELLGERRLWAGIVFLSPEHPLDPSELSSPALSPGHLRFKIRM--DIDDVTRTNKIRDKFWDPGPSADPFMDLRYVWGGFVYLQDLLEQAAVRVLGGGNS-RTGLYLQQMPHPCYVDDVFLRVLSRSLPLFLTLAWIYSVALTVKAVVREKETRLRETMRAMGLSRAVLWLGWFLSCLGPFLVSAALLVLVLKLGNILPYSHPVVIFLFLAAFAVATVAQSFLLSAFFSRANLAAACGGLAYFALYLPYVLCVAWRERLHLGGLLAASLLSPVAFGFGCESLALLEEQGDGAQWHNLGTGPAEDV-FSLAQVSAFLLLDAVIYGLALWYLEAVCPGQYGIPEPWNFPFRRSYWCGP------GPPKSSVLAPAPQDPKVLVEEPPLGLVPGVSIRGLKKHFRG 815          

HSP 2 Score: 52.7582 bits (125), Expect = 2.176e-6
Identity = 30/78 (38.46%), Postives = 46/78 (58.97%), Query Frame = 1
Query:   97 QLKVLLWKNFRLKKRKPITLISEXXXXXXXXXXXXXXRNSIFKFKMDHCEFKEKSMASMGFVPFILDFFCTFNTTCYN 330
            QL +LLWKN+  ++R+PI L+ E+L PL +  I+V VR+S    +   C F  K + S G VP++    C  N +C+ 
Sbjct:    6 QLMLLLWKNYTYRRRQPIQLLVELLWPLFLFFILVAVRHSHPPLEHHECHFPNKPLPSAGTVPWLQGLVCNVNNSCFQ 83          
BLAST of ATP binding cassette subfamily A member 1 vs. Ensembl Mouse
Match: Abca7 (ATP-binding cassette, sub-family A (ABC1), member 7 [Source:MGI Symbol;Acc:MGI:1351646])

HSP 1 Score: 223.787 bits (569), Expect = 2.281e-60
Identity = 162/552 (29.35%), Postives = 271/552 (49.09%), Query Frame = 1
Query:  772 IFDTISSWVFGKIYFSPNSPLTREIMRRANITFETLDYIRLASIEWRL---HFRDWINEAVNNSKLINELKSCKSWYFYFDNNLCETVNAVLNFQTIQSILNK-------------ISLMFSLLEKTLNCTELNKF--MPINESITVENFIKQPMKSVFAVLVINDTFRYLTPS-------NATFLSYQIRIPENQIDSTKHFKVTDKFWTAEPRRETLRDFKYYTSGFLLLQEAIDRAFIEIVTNNETIDVGSSMQIMPYPCYVDDMFIRFITNMMPFMLVIAWVPSVTGLIKSIVYEKERRLKEFMRVMGLGNSVHWIGWFLSTVVVLIFPVTIMXXXXXXXXXXXXXXXXXXXXXXXXXXXXXICQVFMISLFFSNANLASVAGGVIYFILYMPFVVFIRMQSDLSTGFYYLGGLSAQVAFCNAINFIGYWEQSTEGAHFGNLFDGAIIDLKFGVGHCMLMLIVDSVLYLSVAWYVESVFPGQYGVGKAWYFLFTRNYWRAKENISLAHDINNSAQLIIDYDSEGNFENEYTDLRVGISIRNLVKTYPG 2352
            ++  +   + GKI F+P++  TR++M + N TFE L  +R     W +      +++N++ N + L   L    +          +T  A    + I+  L+              +  +  +L + + C  L+K   +P  E++          + ++A +V       L PS       +   L ++IR+  +  D T+  K+ DKFW   P  +   D +Y   GF+ LQ+ +++A + ++    +   G  +Q MP+PCYVDD+F+R ++  +P  L +AW+ SV   +K++V EKE RL+E MR MGL  +V W+GWFLS +   +    ++ L+L   +IL +S   V+FL L  + V+ + Q F++S FFS ANLA+  GG+ YF LY+P+V+ +  +  L  G      L + VAF      +   E+  +GA + NL  G   D+ F +      L++D+V+Y    WY+E+V PGQYG+ + W F F R+YW             +S       D +   E     L  G+SIR L K + G
Sbjct:  280 LWRRLKPLILGKILFAPDTNFTRKLMAQVNQTFEELALLRDLHELWGVLGPQIFNFMNDSTNVAMLQRLLDVGGT------GQRQQTPRAQKKLEAIKDFLDPSRGGYSWREAHADMGRLAGILGQMMECVSLDKLEAVPSEEALVSRALELLGERRLWAGIVFLSPEHPLDPSELSSPALSPGHLRFKIRM--DIDDVTRTNKIRDKFWDPGPSADPFMDLRYVWGGFVYLQDLLEQAAVRVLGGGNS-RTGLYLQQMPHPCYVDDVFLRVLSRSLPLFLTLAWIYSVALTVKAVVREKETRLRETMRAMGLSRAVLWLGWFLSCLGPFLVSAALLVLVLKLGNILPYSHPVVIFLFLAAFAVATVAQSFLLSAFFSRANLAAACGGLAYFALYLPYVLCVAWRERLHLGGLLAASLLSPVAFGFGCESLALLEEQGDGAQWHNLGTGPAEDV-FSLAQVSAFLLLDAVIYGLALWYLEAVCPGQYGIPEPWNFPFRRSYWCGP------GPPKSSVLAPAPQDPKVLVEEPPLGLVPGVSIRGLKKHFRG 815          

HSP 2 Score: 52.7582 bits (125), Expect = 2.176e-6
Identity = 30/78 (38.46%), Postives = 46/78 (58.97%), Query Frame = 1
Query:   97 QLKVLLWKNFRLKKRKPITLISEXXXXXXXXXXXXXXRNSIFKFKMDHCEFKEKSMASMGFVPFILDFFCTFNTTCYN 330
            QL +LLWKN+  ++R+PI L+ E+L PL +  I+V VR+S    +   C F  K + S G VP++    C  N +C+ 
Sbjct:    6 QLMLLLWKNYTYRRRQPIQLLVELLWPLFLFFILVAVRHSHPPLEHHECHFPNKPLPSAGTVPWLQGLVCNVNNSCFQ 83          
BLAST of ATP binding cassette subfamily A member 1 vs. Ensembl Mouse
Match: Abca4 (ATP-binding cassette, sub-family A (ABC1), member 4 [Source:MGI Symbol;Acc:MGI:109424])

HSP 1 Score: 223.402 bits (568), Expect = 3.449e-60
Identity = 167/553 (30.20%), Postives = 274/553 (49.55%), Query Frame = 1
Query:  796 VFGKIYFSPNSPLTREIMRRANITFETLDYIRLASIEWR-LHFRDW-INEAVNNSKLINELKSCKSWYFYFDNNLCE---TVNAVLNF-----QTIQS----------ILNKISLMFSLLEKTLNCTELNKFMPINESITVENFIKQPMKS--VFAVLVINDTFRYLTPSNATFLSYQIRIPENQIDSTKHFKVTDKFWTAEPRRETLRDFKYYTSGFLLLQEAIDRAFIEIVTNNETIDVGSSMQIMPYPCYVDDMFIRFITNMMPFMLVIAWVPSVTGLIKSIVYEKERRLKEFMRVMGLGNSVHWIGWFLSTVVVLIFPVTIMXXXXXXXXXXXXXXXXXXXXXXXXXXXXXICQVFMISLFFSNANLASVAGGVIYFILYMPFVVFI----RMQSDLSTGFYYLGGLSAQVAFCNAINFIGYWEQSTEGAHFGNLFDGAIIDLKFGVGHCMLMLIVDSVLYLSVAWYVESVFPGQYGVGKAWYFLFTRNYWRAKENISLAHD--INNSAQLIIDYDS----EGN----FENEYTDLRVGISIRNLVKTY 2346
            + GKI F+P+SP  R IM+ AN TFE LD +R     W  +  + W   E      +I +     +   + +  L E   T  AVLNF     Q  Q+          I N       L  + L C  L+KF   ++ + +       ++    +A +V    + + + S    + Y+IR+  + ++ T   K+ D++W + PR + + DF+Y   GF  LQ+ +++  ++     E   +G  +Q MPYPC+VDD F+  +    P  +V+AW+ SV+  +K IV EKE RLKE ++  G+ N+V W  WFL +  ++   + +++L +++  IL +S   ++FL LL +  + I Q F++S  FS A+LA+   GVIYF LY+P V+      RM +DL T    L    + VAF     ++  +E+   G  + N+    +   +F     M M+++D+ LY  +AWY++ VFPG YG    WYFL   +YW   E  S   +  +  +  L  + +     EG     FE E   L  G+ ++NLVK +
Sbjct:  394 LMGKILFTPDSPAARRIMKNANSTFEELDRVRKLVKAWEEVGPQIWYFFEKSTQMTVIRDTLQHPTVKDFINRQLGEEGITTEAVLNFFSNGPQEKQADDMTSFDWRDIFNITDRFLRLANQYLECLVLDKFESYDDEVQLTQRALSLLEENRFWAGVVFPGMYPWAS-SLPPHVKYKIRMDIDVVEKTN--KIKDRYWDSGPRADPVEDFRYIWGGFAYLQDMVEQGIVKSQMQAEP-PIGVYLQQMPYPCFVDDSFMIILNRCFPIFMVLAWIYSVSMTVKGIVLEKELRLKETLKNQGVSNAVIWCTWFLDSFSIMALSIFLLTLFIMHGRILHYSDPFILFLFLLAFATATIMQSFLLSTLFSKASLAAACSGVIYFTLYLPHVLCFAWQDRMTADLKTTVSLL----SSVAFGFGTEYLVRFEEQGLGLQWSNIGKSPLEGDEFSFLLSMKMMLLDAALYGLLAWYLDQVFPGDYGTPLPWYFLLQESYWLGGEGCSTREERALEKTEPLTEEMEDPEHPEGMNDSFFERELPGLVPGVCVKNLVKVF 938          

HSP 2 Score: 56.225 bits (134), Expect = 1.940e-7
Identity = 27/81 (33.33%), Postives = 50/81 (61.73%), Query Frame = 1
Query:   88 FTKQLKVLLWKNFRLKKRKPITLISEXXXXXXXXXXXXXXRNSIFKFKMDHCEFKEKSMASMGFVPFILDFFCTFNTTCYN 330
            F +Q+++LLWKN+ L+KR+ I  + E++ PL + ++++ +RN+   +    C F  K+M S G +P++   FC  N  C+ 
Sbjct:    3 FLRQIQLLLWKNWTLRKRQKIRFVVELVWPLSLFLVLIWLRNANPLYSQHECHFPNKAMPSAGLLPWLQGIFCNMNNPCFQ 83          
BLAST of ATP binding cassette subfamily A member 1 vs. UniProt/SwissProt
Match: sp|O95477|ABCA1_HUMAN (Phospholipid-transporting ATPase ABCA1 OS=Homo sapiens OX=9606 GN=ABCA1 PE=1 SV=3)

HSP 1 Score: 274.248 bits (700), Expect = 2.430e-76
Identity = 178/561 (31.73%), Postives = 295/561 (52.58%), Query Frame = 1
Query:  739 RNFENFFGNSNIFDTISSWVFGKIYFSPNSPLTREIMRRANITFETLDYIRLASIEWR-LHFRDWI-NEAVNNSKLINELKSCKSWYFYFDNNLCE---TVNAVLNF-----QTIQS----------ILNKISLMFSLLEKTLNCTELNKFMPINESITVENFIKQPM--KSVFAVLVINDTFRYLTPSNATF---LSYQIRIPENQIDSTKHFKVTDKFWTAEPRRETLRDFKYYTSGFLLLQEAIDRAFIEIVTNNETIDVGSSMQIMPYPCYVDDMFIRFITNMMPFMLVIAWVPSVTGLIKSIVYEKERRLKEFMRVMGLGNSVHWIGWFLSTVVVLIFPVTIMXXXXXXXXXXXXXXXXXXXXXXXXXXXXXICQVFMISLFFSNANLASVAGGVIYFILYMPFVVFIRMQSDLSTGFYYLGGLSAQVAFCNAINFIGYWEQSTEGAHFGNLFDGAIIDLKFGVGHCMLMLIVDSVLYLSVAWYVESVFPGQYGVGKAWYFLFTRNYWRAKENISLAHDINNSAQLIIDYDSEGNFENEYTDLRVGISIRNLVKTY 2346
            +N E+   +  I+  +   + GKI ++P++P TR++M   N TF+ L         W  L  + W   E      L+  L   +    +++  L     T   ++ F     + +QS            N+ +     + + + C  LNK  PI   + + N   + +  +  +A +V    F  +TP +      + Y+IR+  + ++ T   K+ D +W   PR +   D +Y   GF  LQ+ +++A I ++T  E    G  MQ MPYPCYVDD+F+R ++  MP  + +AW+ SV  +IK IVYEKE RLKE MR+MGL NS+ W  WF+S+++ L+    ++ ++L   ++L +S  +VVF+ L ++ V  I Q F+IS  FS ANLA+  GG+IYF LY+P+V+ +  Q  +         L + VAF     +   +E+   G  + NLF+  + +  F +   + M++ D+ LY  + WY+E+VFPGQYG+ + WYF  T++YW  +E+   +H  +N  ++     SE   E E T L++G+SI+NLVK Y
Sbjct:  360 KNLESSPLSRIIWKALKPLLVGKILYTPDTPATRQVMAEVNKTFQELAVFHDLEGMWEELSPKIWTFMENSQEMDLVRMLLDSRDNDHFWEQQLDGLDWTAQDIVAFLAKHPEDVQSSNGSVYTWREAFNETNQAIRTISRFMECVNLNKLEPIATEVWLINKSMELLDERKFWAGIV----FTGITPGSIELPHHVKYKIRMDIDNVERTN--KIKDGYWDPGPRADPFEDMRYVWGGFAYLQDVVEQAIIRVLTGTEK-KTGVYMQQMPYPCYVDDIFLRVMSRSMPLFMTLAWIYSVAVIIKGIVYEKEARLKETMRIMGLDNSILWFSWFISSLIPLLVSAGLLVVILKLGNLLPYSDPSVVFVFLSVFAVVTILQCFLISTLFSRANLAAACGGIIYFTLYLPYVLCVAWQDYVGFTLKIFASLLSPVAFGFGCEYFALFEEQGIGVQWDNLFESPVEEDGFNLTTSVSMMLFDTFLYGVMTWYIEAVFPGQYGIPRPWYFPCTKSYWFGEESDEKSHPGSNQKRI-----SEICMEEEPTHLKLGVSIQNLVKVY 908          
BLAST of ATP binding cassette subfamily A member 1 vs. UniProt/SwissProt
Match: sp|P41233|ABCA1_MOUSE (Phospholipid-transporting ATPase ABCA1 OS=Mus musculus OX=10090 GN=Abca1 PE=1 SV=4)

HSP 1 Score: 272.322 bits (695), Expect = 1.089e-75
Identity = 179/561 (31.91%), Postives = 296/561 (52.76%), Query Frame = 1
Query:  739 RNFENFFGNSNIFDTISSWVFGKIYFSPNSPLTREIMRRANITFETLDYIRLASIEWR-LHFRDWI-NEAVNNSKLINELKSCKSWYFYFDNNL------CETVNAVL--NFQTIQS----------ILNKISLMFSLLEKTLNCTELNKFMPINESITVENFIKQPM--KSVFAVLVINDTFRYLTPSNATF---LSYQIRIPENQIDSTKHFKVTDKFWTAEPRRETLRDFKYYTSGFLLLQEAIDRAFIEIVTNNETIDVGSSMQIMPYPCYVDDMFIRFITNMMPFMLVIAWVPSVTGLIKSIVYEKERRLKEFMRVMGLGNSVHWIGWFLSTVVVLIFPVTIMXXXXXXXXXXXXXXXXXXXXXXXXXXXXXICQVFMISLFFSNANLASVAGGVIYFILYMPFVVFIRMQSDLSTGFYYLGGLSAQVAFCNAINFIGYWEQSTEGAHFGNLFDGAIIDLKFGVGHCMLMLIVDSVLYLSVAWYVESVFPGQYGVGKAWYFLFTRNYWRAKENISLAHDINNSAQLIIDYDSEGNFENEYTDLRVGISIRNLVKTY 2346
            +N E+   +  I+  +   + GKI ++P++P TR++M   N TF+ L         W  L  + W   E      L+  L   +    +++  L       + + A L  N + +QS            N+ +     + + + C  LNK  PI   + + N   + +  +  +A +V    F  +TP +      + Y+IR+  + ++ T   K+ D +W   PR +   D +Y   GF  LQ+ +++A I ++T +E    G  +Q MPYPCYVDD+F+R ++  MP  + +AW+ SV  +IKSIVYEKE RLKE MR+MGL N + W  WF+S+++ L+    ++ ++L   ++L +S  +VVF+ L ++ +  I Q F+IS  FS ANLA+  GG+IYF LY+P+V+ +  Q  +         L + VAF     +   +E+   G  + NLF+  + +  F +   + M++ D+ LY  + WY+E+VFPGQYG+ + WYF  T++YW  +E    +H    S+Q  +   SE   E E T LR+G+SI+NLVK Y
Sbjct:  360 KNLESSPLSRIIWKALKPLLVGKILYTPDTPATRQVMAEVNKTFQELAVFHDLEGMWEELSPQIWTFMENSQEMDLVRTLLDSRGNDQFWEQKLDGLDWTAQDIMAFLAKNPEDVQSPNGSVYTWREAFNETNQAIQTISRFMECVNLNKLEPIPTEVRLINKSMELLDERKFWAGIV----FTGITPDSVELPHHVKYKIRMDIDNVERTN--KIKDGYWDPGPRADPFEDMRYVWGGFAYLQDVVEQAIIRVLTGSEK-KTGVYVQQMPYPCYVDDIFLRVMSRSMPLFMTLAWIYSVAVIIKSIVYEKEARLKETMRIMGLDNGILWFSWFVSSLIPLLVSAGLLVVILKLGNLLPYSDPSVVFVFLSVFAMVTILQCFLISTLFSRANLAAACGGIIYFTLYLPYVLCVAWQDYVGFSIKIFASLLSPVAFGFGCEYFALFEEQGIGVQWDNLFESPVEEDGFNLTTAVSMMLFDTFLYGVMTWYIEAVFPGQYGIPRPWYFPCTKSYWFGEEIDEKSHP--GSSQKGV---SEICMEEEPTHLRLGVSIQNLVKVY 908          
BLAST of ATP binding cassette subfamily A member 1 vs. UniProt/SwissProt
Match: sp|Q8IZY2|ABCA7_HUMAN (Phospholipid-transporting ATPase ABCA7 OS=Homo sapiens OX=9606 GN=ABCA7 PE=1 SV=3)

HSP 1 Score: 234.572 bits (597), Expect = 4.294e-63
Identity = 162/540 (30.00%), Postives = 269/540 (49.81%), Query Frame = 1
Query:  796 VFGKIYFSPNSPLTREIMRRANITFETLDYIRLASIEWRL---HFRDWINEAVNNS---KLINELKSCKSWYFYFDNNLCETVNAVLNFQTI----QSILNKISLMFSLLEKTLNCTELNKF-MPINESITVENFIKQPMKSVFAVLVI-------NDTFRYLTPS-NATFLSYQIRIPENQIDS-TKHFKVTDKFWTAEPRRETLRDFKYYTSGFLLLQEAIDRAFIEIVTNNETIDVGSSMQIMPYPCYVDDMFIRFITNMMPFMLVIAWVPSVTGLIKSIVYEKERRLKEFMRVMGLGNSVHWIGWFLSTVVVLIFPVTIMXXXXXXXXXXXXXXXXXXXXXXXXXXXXXICQVFMISLFFSNANLASVAGGVIYFILYMPFVVFIRMQSDLSTGFYYLGGLSAQVAFCNAINFIGYWEQSTEGAHFGNLFDGAIIDLKFGVGHCMLMLIVDSVLYLSVAWYVESVFPGQYGVGKAWYFLFTRNYWRAKENISLAHDINNSAQLIIDYDSEGNFENEYTDLRVGISIRNLVKTYPGA 2355
            + GK+ F+P++P TR++M + N TFE L  +R     W +       ++N++ N +   +L+      +        +  E + + L+  +     Q     +  +   L +   C  L+K     +E+  V   ++   +  F   V+       +D   + TP      +  +IR+    ID  T+  K+ D+FW   P  + L D +Y   GF+ LQ+ ++RA + +++       G  +Q MPYPCYVDD+F+R ++  +P  L +AW+ SVT  +K++V EKE RL++ MR MGL  +V W+GWFLS +   +    ++ L+L    IL +S   VVFL L  + V+ + Q F++S FFS ANLA+  GG+ YF LY+P+V+ +  +  L  G      L + VAF      +   E+  EGA + N+      D+ F +     +L++D+ LY    WY+E+V PGQYG+ + W F F R+YW             + A      D +   E     L  G+S+R+L K +PG+
Sbjct:  291 ILGKLLFAPDTPFTRKLMAQVNRTFEELTLLRDVREVWEMLGPRIFTFMNDSSNVAMLQRLLQMQDEGRRQPRPGGRDHMEALRSFLDPGSGGYSWQDAHADVGHLVGTLGRVTECLSLDKLEAAPSEAALVSRALQLLAEHRFWAGVVFLGPEDSSDPTEHPTPDLGPGHVRIKIRM---DIDVVTRTNKIRDRFWDPGPAADPLTDLRYVWGGFVYLQDLVERAAVRVLSGANP-RAGLYLQQMPYPCYVDDVFLRVLSRSLPLFLTLAWIYSVTLTVKAVVREKETRLRDTMRAMGLSRAVLWLGWFLSCLGPFLLSAALLVLVLKLGDILPYSHPGVVFLFLAAFAVATVTQSFLLSAFFSRANLAAACGGLAYFSLYLPYVLCVAWRDRLPAGGRVAASLLSPVAFGFGCESLALLEEQGEGAQWHNVGTRPTADV-FSLAQVSGLLLLDAALYGLATWYLEAVCPGQYGIPEPWNFPFRRSYWCGPR------PPKSPAPCPTPLDPKVLVEEAPPGLSPGVSVRSLEKRFPGS 819          

HSP 2 Score: 55.4546 bits (132), Expect = 2.093e-6
Identity = 32/82 (39.02%), Postives = 48/82 (58.54%), Query Frame = 1
Query:   88 FTKQLKVLLWKNFRLKKRKPITLISEXXXXXXXXXXXXXXRNSIFKFKMDHCEFKEKSMASMGFVPFILDFFCTFNTTCYNK 333
            F  QL +LLWKNF  ++R+P+ L+ E+L PL +  I+V VR+S    +   C F  K + S G VP++    C  N TC+ +
Sbjct:    3 FWTQLMLLLWKNFMYRRRQPVQLLVELLWPLFLFFILVAVRHSHPPLEHHECHFPNKPLPSAGTVPWLQGLICNVNNTCFPQ 84          
BLAST of ATP binding cassette subfamily A member 1 vs. UniProt/SwissProt
Match: sp|Q7TNJ2|ABCA7_RAT (ATP-binding cassette sub-family A member 7 OS=Rattus norvegicus OX=10116 GN=Abca7 PE=1 SV=1)

HSP 1 Score: 232.261 bits (591), Expect = 2.844e-62
Identity = 160/540 (29.63%), Postives = 274/540 (50.74%), Query Frame = 1
Query:  796 VFGKIYFSPNSPLTREIMRRANITFETLDYIRLASIEWRL---HFRDWINEAVNNSKLINELKSCKSWYFYFDNNLCETVNAVLNFQTI-------QSILNKISLMFSLLEKTLNCTELNKF--MPINESITVENFIKQPMKSVFAVLVIN------DTFRYLTPSNATFLSYQIRIPENQIDSTKHFKVTDKFWTAEPRRETLRDFKYYTSGFLLLQEAIDRAFIEIVTNNETIDVGSSMQIMPYPCYVDDMFIRFITNMMPFMLVIAWVPSVTGLIKSIVYEKERRLKEFMRVMGLGNSVHWIGWFLSTVVVLIFPVTIMXXXXXXXXXXXXXXXXXXXXXXXXXXXXXICQVFMISLFFSNANLASVAGGVIYFILYMPFVVFIRMQSDLSTGFYYLGGLSAQVAFCNAINFIGYWEQSTEGAHFGNLFDGAIIDLKFGVGHCMLMLIVDSVLYLSVAWYVESVFPGQYGVGKAWYFLFTRNYW--RAKENISLAHDINNSAQLIIDYDSEGNFENEYTDLRVGISIRNLVKTYPGA 2355
            + GKI F+P++  TR++M + N TFE L  +R     W +      +++N++ N + L   L    + +        + + A+ +F          Q     +  +  +L + L C  L+K   +P  E++          + ++A +V        D+    +P+       +++I  +  D T+  K+ DKFW   P  + L D +Y   GF+ LQ+ +++A + +++  ++   G  +Q MP+PCYVDD+F+R ++  +P  L +AW+ SV   +K++V EKE RL+E MR MGL  +V W+GWFLS +   +    ++ L+L   +IL +S   VVFL L  + V+ + Q F++S FFS ANLA+  GG+ YF LY+P+V+ +  +  L  G      L + VAF      +   E+  +GA + NL  G   D+ F +      L++D+V+Y    WY+E+V PGQYG+ + W F F R+YW        S+        +++++    G        L  G+SIR L K + G+
Sbjct:  288 ILGKILFAPDTNFTRKLMAQVNQTFEELALLRDLHELWGVLGPQIFNFMNDSTNVAMLQKLLDVEGTGWQQQTPKGQKQLEAIRDFLDPSRGRYNWQEAHADMGRLAEILGQILECVSLDKLEAVPSEEALVSRALELLGERRLWAGIVFLSPEHPLDSSEPPSPTTTGPGHLRVKIRMDIDDVTRTNKIRDKFWDPGPSADPLMDLRYVWGGFVYLQDLLEQAAVRVLSGRDS-RAGLYLQQMPHPCYVDDVFLRVLSRSLPLFLTLAWIYSVALTVKAVVREKETRLRETMRAMGLSRAVLWLGWFLSCLGPFLVSAALLVLVLKLGNILPYSHPVVVFLFLAAFAVATVAQSFLLSAFFSRANLAAACGGLAYFALYLPYVLCVAWRERLPLGGLLAVSLLSPVAFGFGCESLALLEEQGDGAQWHNLGTGPAEDV-FSLAQVSAFLLLDAVIYGLALWYLEAVCPGQYGIPEPWNFPFRRSYWCGPGPPKSSVLAPAPQDPKVLVEEPPPG--------LVPGVSIRGLKKHFRGS 817          

HSP 2 Score: 56.6102 bits (135), Expect = 9.604e-7
Identity = 34/111 (30.63%), Postives = 56/111 (50.45%), Query Frame = 1
Query:   88 FTKQLKVLLWKNFRLKKRKPITLISEXXXXXXXXXXXXXXRNSIFKFKMDHCEFKEKSMASMGFVPFILDFFCTFNTTCYNKTQINWNENYSSIYAFKMFTKNLYNVYQTL 420
            F  QL +LLWKN+  ++R+PI L+ E+L PL +  I+V VR+S    +   C F  K + S G VP++    C  N +C+            S +   + ++ L + +  L
Sbjct:    3 FCTQLMLLLWKNYTYRRRQPIQLVVELLWPLFLFFILVAVRHSHPPLEHHECHFPNKPLPSAGTVPWLQGLVCNVNNSCFQHPTPGEKPGVLSNFKDSLISRLLADAHTVL 113          
BLAST of ATP binding cassette subfamily A member 1 vs. UniProt/SwissProt
Match: sp|O35600|ABCA4_MOUSE (Retinal-specific phospholipid-transporting ATPase ABCA4 OS=Mus musculus OX=10090 GN=Abca4 PE=2 SV=1)

HSP 1 Score: 223.402 bits (568), Expect = 2.413e-59
Identity = 167/553 (30.20%), Postives = 274/553 (49.55%), Query Frame = 1
Query:  796 VFGKIYFSPNSPLTREIMRRANITFETLDYIRLASIEWR-LHFRDW-INEAVNNSKLINELKSCKSWYFYFDNNLCE---TVNAVLNF-----QTIQS----------ILNKISLMFSLLEKTLNCTELNKFMPINESITVENFIKQPMKS--VFAVLVINDTFRYLTPSNATFLSYQIRIPENQIDSTKHFKVTDKFWTAEPRRETLRDFKYYTSGFLLLQEAIDRAFIEIVTNNETIDVGSSMQIMPYPCYVDDMFIRFITNMMPFMLVIAWVPSVTGLIKSIVYEKERRLKEFMRVMGLGNSVHWIGWFLSTVVVLIFPVTIMXXXXXXXXXXXXXXXXXXXXXXXXXXXXXICQVFMISLFFSNANLASVAGGVIYFILYMPFVVFI----RMQSDLSTGFYYLGGLSAQVAFCNAINFIGYWEQSTEGAHFGNLFDGAIIDLKFGVGHCMLMLIVDSVLYLSVAWYVESVFPGQYGVGKAWYFLFTRNYWRAKENISLAHD--INNSAQLIIDYDS----EGN----FENEYTDLRVGISIRNLVKTY 2346
            + GKI F+P+SP  R IM+ AN TFE LD +R     W  +  + W   E      +I +     +   + +  L E   T  AVLNF     Q  Q+          I N       L  + L C  L+KF   ++ + +       ++    +A +V    + + + S    + Y+IR+  + ++ T   K+ D++W + PR + + DF+Y   GF  LQ+ +++  ++     E   +G  +Q MPYPC+VDD F+  +    P  +V+AW+ SV+  +K IV EKE RLKE ++  G+ N+V W  WFL +  ++   + +++L +++  IL +S   ++FL LL +  + I Q F++S  FS A+LA+   GVIYF LY+P V+      RM +DL T    L    + VAF     ++  +E+   G  + N+    +   +F     M M+++D+ LY  +AWY++ VFPG YG    WYFL   +YW   E  S   +  +  +  L  + +     EG     FE E   L  G+ ++NLVK +
Sbjct:  394 LMGKILFTPDSPAARRIMKNANSTFEELDRVRKLVKAWEEVGPQIWYFFEKSTQMTVIRDTLQHPTVKDFINRQLGEEGITTEAVLNFFSNGPQEKQADDMTSFDWRDIFNITDRFLRLANQYLECLVLDKFESYDDEVQLTQRALSLLEENRFWAGVVFPGMYPWAS-SLPPHVKYKIRMDIDVVEKTN--KIKDRYWDSGPRADPVEDFRYIWGGFAYLQDMVEQGIVKSQMQAEP-PIGVYLQQMPYPCFVDDSFMIILNRCFPIFMVLAWIYSVSMTVKGIVLEKELRLKETLKNQGVSNAVIWCTWFLDSFSIMALSIFLLTLFIMHGRILHYSDPFILFLFLLAFATATIMQSFLLSTLFSKASLAAACSGVIYFTLYLPHVLCFAWQDRMTADLKTTVSLL----SSVAFGFGTEYLVRFEEQGLGLQWSNIGKSPLEGDEFSFLLSMKMMLLDAALYGLLAWYLDQVFPGDYGTPLPWYFLLQESYWLGGEGCSTREERALEKTEPLTEEMEDPEHPEGMNDSFFERELPGLVPGVCVKNLVKVF 938          

HSP 2 Score: 56.225 bits (134), Expect = 1.357e-6
Identity = 27/81 (33.33%), Postives = 50/81 (61.73%), Query Frame = 1
Query:   88 FTKQLKVLLWKNFRLKKRKPITLISEXXXXXXXXXXXXXXRNSIFKFKMDHCEFKEKSMASMGFVPFILDFFCTFNTTCYN 330
            F +Q+++LLWKN+ L+KR+ I  + E++ PL + ++++ +RN+   +    C F  K+M S G +P++   FC  N  C+ 
Sbjct:    3 FLRQIQLLLWKNWTLRKRQKIRFVVELVWPLSLFLVLIWLRNANPLYSQHECHFPNKAMPSAGLLPWLQGIFCNMNNPCFQ 83          
BLAST of ATP binding cassette subfamily A member 1 vs. TrEMBL
Match: A0A4X2KQE6 (ATP binding cassette subfamily A member 7 OS=Vombatus ursinus OX=29139 GN=ABCA7 PE=4 SV=1)

HSP 1 Score: 294.278 bits (752), Expect = 1.270e-80
Identity = 226/803 (28.14%), Postives = 370/803 (46.08%), Query Frame = 1
Query:   88 FTKQLKVLLWKNFRLKKRKPITLISEXXXXXXXXXXXXXXRNSIFKFKMDHCEFKEKSMASMGFVPFILDFFCTFNTTCY----------NKTQIN----WNE-------------------NYSSIYAFKMFTKNLYNVYQTLPKEKLTVNSLITWATNHKFEIDQLISNIMPIIKLLSPLIASLKEADTENLTASKPIIIQIFKVFCGSDENDFTEF----YYKFSSISTKNVSGQTNAGSQFMNESNVTCERNFENFFGNSNIFDTISSW-----VFGKIYFSPNSPLTREIMRRANITFETLDYIRLASIEWRLHFRDWINEAVNNSKLINELKSCKSWYFYFDNNLCETVNAVLNFQ----TIQSILNKISLMFSLLEKTLNCTELNKFMPI-NESITVENFIKQPMKSVFAVLVINDTFRYLTPSNATFLSYQIRIPENQIDSTKHFKVTDKFWTAEPRRETLRDFKYYTSGFLLLQEAIDRAFIEIVTNNETIDVGSSMQIMPYPCYVDDMFIRFITNMMPFMLVIAWVPSVTGLIKSIVYEKERRLKEFMRVMGLGNSVHWIGWFLSTVVVLIFPVTIMXXXXXXXXXXXXXXXXXXXXXXXXXXXXXICQVFMISLFFSNANLASVAGGVIYFILYMPFVVFIRMQSDLSTGFYYLGGLSAQVAFCNAINFIGYWEQSTEGAHFGNLFDGAIIDLKFGVGHCMLMLIVDSVLYLSVAWYVESVFPGQYGVGKAWYFLFTRNYWRAKENISLAHDINNSAQLIIDYDSEGNFENEYTDLRVGISIRNLVKTYPGA 2355
            F  QL +LLWKNF  +KRKP+ L+ E+L PL + +I+V VR S   F+   C F  K + S G +P+     C  N  CY          ++T+      WNE                   +   + +F++   +L  V   +P      ++ +  A +   ++  L S        L+ L A L+ A           +  + +V CG   +   E     +Y+   +      GQ    S   N ++  C++  E+    ++    +  W     V GKI ++P++PLTR +M   N TF  L  ++     W +     I+  +NNS  +  LK    W      N    +   L       + +     I+L+   + K L C  L+K  P+  E   +E  ++   +  F   V+   F  L    A     +++I  +  D T+  K+ D+FW   P  + + D +Y   GF+ LQ+ ++ A I ++ N+        +Q MPYPCYVDD+F+R +   +P  L +AW+ SV   +K IV EKE RL++ M  MGL  SV W  WF+S++V  +   +++ L+L    IL  S    VFL L  + V+ ICQ F+ S  FS AN+A+  GG++YF LY+P+V+ +  +  L         L + VAF     +   +E+   G  + N+    +    + +  C  +LI+D+ LY +  WY+E++ PGQYG+ + W F F ++YW   E  S + D   S       D +   E+    L+VG+S++ LVK YPG+
Sbjct:    3 FWTQLMLLLWKNFMYRKRKPVQLVIELLWPLFLFLILVAVRQSHPPFEHHECHFPNKPLPSAGMLPWFQGLLCNMNNPCYRYATPGETPVSRTECGRAGGWNEMGKDEGGGHVVSGSDSAAGSLGDLTSFQVRGSSL-GVPSPVPS-----HTSVGLAAHLSLQLSTLPS--------LAELRAELRRAPGPGGP-----VEGVSRVLCGKSRDQGVEIPSLNWYEDDDLKMMLGWGQGRLASPMDNSTSPFCQKLIESM--EAHPISRLLWWRLKPLVLGKILYTPDTPLTRRVMAEVNQTFHQLALLQELHGLW-MELGPQISSFMNNSAQVALLKVEMGWQLRLPRNGTSAIRTFLGLDGSGYSWKEAHEDITLIVDKVGKVLECVSLDKLEPVVTEDSLMERAVELLGQRRFWAGVV---FLGLQDGGAPG-HIRLKIRMDIDDVTRTNKIKDRFWDPGPAADPILDMRYVWGGFVYLQDLLEGAVIRVL-NSSAHPASIYLQQMPYPCYVDDVFLRVLNRSLPLFLTLAWIYSVALTVKGIVQEKEARLRDTMLAMGLDRSVLWGSWFVSSLVPFLVSSSLLVLILKQGDILPHSDPFPVFLFLAAFAVATICQSFLFSAAFSRANVAAACGGLLYFTLYLPYVLCVAWRDHLPPALRLAASLLSPVAFGFGCEYFSLYEEQGVGIQWHNMGRSPVAGDGYNLALCEALLILDAGLYATATWYIEAICPGQYGIPQPWNFPFRKSYW-CGELASASLDPTPSKD-----DPQVLVEDPSPGLQVGVSLQGLVKYYPGS 772          
BLAST of ATP binding cassette subfamily A member 1 vs. TrEMBL
Match: A0A3Q3RRK1 (Zgc:172302 OS=Mastacembelus armatus OX=205130 PE=4 SV=1)

HSP 1 Score: 288.886 bits (738), Expect = 8.451e-79
Identity = 243/823 (29.53%), Postives = 393/823 (47.75%), Query Frame = 1
Query:   88 FTKQLKVLLWKNFRLKKRKPITLISEXXXXXXXXXXXXXXRNSIFKFKMDHCEFKEKSMASMGFVPFILDFFCTFNTTCYNKTQINWNENY-----SSIYAFK----MFTKNLYNVYQTLPKEK-LTVNS-----LITWATNHKFEIDQL--------ISNIMPIIK-LLSPL--------IASLKEADTENLTASKPIIIQIF-KVFCGSDENDFTEF----YYKFSSISTKNVSGQTNAGSQFMNESNVT-CERNFENFFGNSN---IFDTISSWVFGKIYFSPNSPLTREIMRRANITFETLDYI---RLASIEWRLHFRDWINEAVNNSKLINELKSCKSWYFYFDNNLCET---VNAVLNFQTIQS---------------ILNKISLMFSLLEKTLNCTELNKFMPINESITVEN-FIKQPM-----KSVFA--VLVINDTFRYLTPSNATFLSYQIRIPENQIDSTKHFKVTDKFWTAEPRRETLRDFKYYTSGFLLLQEAIDRAFIEIVTNNETIDVGSSMQIMPYPCYVDDMFIRFITNMMPFMLVIAWVPSVTGLIKSIVYEKERRLKEFMRVMGLGNSVHWIGWFLSTVVVLIFPVTIMXXXXXXXXXXXXXXXXXXXXXXXXXXXXXICQVFMISLFFSNANLASVAGGVIYFILYMPFVVFIRMQSDLSTGFYYLGGLSAQVAFCNAINFIGYWEQSTEGAHFGNLFDGAIIDLKFGVGHCMLMLIVDSVLYLSVAWYVESVFPGQYGVGKAWYFLFTRNYWRAKENISLAHDINNSAQLIIDYDSEGNFENEYTDLRVGISIRNLVKTY 2346
            F KQL +LLWKN   ++R  I LI E+L PL + +I++ VR+S   +K   C F  K++ S G +P+I    C  N  C++               +SI+ F+    +F  N +     LP E+ L  N      L+T ++     +DQL        +S I    K L +PL         A+L+   TEN TA      + F ++ CG  E          +Y+ + I  K+  G+       ++  N   C+        N     ++  I     GK+ ++PN+P  +++M+  N TFE L  +     A IE     ++++  +V   +L+ +L          +  L +T   V+ + +F +  S               I N I+   + L +   C  LNK     E +  E   I + +     + ++A  V ++ +T     P + T   Y+IR+  +  D T+  K+ D+FW   P  +   D +Y   GF+ +Q+ ++RA   ++T  +    G  +Q MPYPCYVDD+F+R +   +P  + +AW+ SV  +IK +VYEKE RLKE MR+MGLG    W+ W +S++V  +    ++  LL +  IL +S   VVF  L+ +  + I Q F+IS FFS ANLA+  GG+IYF LY+P+V+ +  +  L+T    L    + VAF     +   +E+   G  + NL    +    +     ++ML VD+ +Y   AWY+E+VFPG+YG+ + WYF+F  NYW       +  +             E + E E T+L +G+SIRNLVK Y
Sbjct:    3 FFKQLTLLLWKNITYRRRNKIQLIIELLWPLFLFVILISVRHSHPPYKQSQCHFPNKALPSAGTLPWIQGIICNINNPCFHSPTPGETPGQVGNFDNSIFCFERSKLLFCVNAFVFTADLPVEEYLRANETFSTFLLTNSSLSPVTVDQLMKSRLNFQVSYICECCKSLKNPLKPTYFANMSAALRLLSTENRTALPTESFRAFSRIMCGHPEVGGERIPSLNWYEDNDI--KSFLGKNGTEDTDLDHDNTPFCKSLIHGLESNPLSRIVWRGIKPLFIGKLLYTPNTPAVQQVMKEVNKTFEDLQILLELNEAWIEVGPRIKNYMESSVE-IQLLQDLLRRPEVAVLVNLRLQDTSWTVSRITHFLSTPSPDAPRLPGEPPTWLDIYNDINHTITTLAQITECFSLNKL----EGLETEGQLIDRALVLLEDRQLWAGVVFLLPNTSSLRVPPHVT---YKIRMDID--DVTRTNKIKDRFWDPGPAADPFNDMRYIWGGFVYIQDLVERAVSRVLTGVQQT-TGIYVQQMPYPCYVDDVFLRVLNRSLPLFMTLAWIYSVAMIIKGVVYEKEARLKETMRIMGLGTGTLWLSWLISSMVPFLVSAVLLIALLKWGDILPYSDATVVFFFLMAFATATIMQCFLISTFFSKANLAAACGGLIYFGLYLPYVLCVAWRDHLNTTHRVLASFLSPVAFGFGCEYFSQYEEQGVGIQWYNLRSSPVEGDSYSFTLSIIMLYVDAFIYAIAAWYIEAVFPGEYGIPRPWYFIFQLNYWGG-----VPLEAGMPIPPAPSEQDEDHIEPEPTNLILGVSIRNLVKIY 807          
BLAST of ATP binding cassette subfamily A member 1 vs. TrEMBL
Match: A0A4W3K1G7 (Uncharacterized protein OS=Callorhinchus milii OX=7868 GN=abca1 PE=4 SV=1)

HSP 1 Score: 288.886 bits (738), Expect = 8.589e-79
Identity = 226/812 (27.83%), Postives = 386/812 (47.54%), Query Frame = 1
Query:   88 FTKQLKVLLWKNFRLKKRKPITLISEXXXXXXXXXXXXXXRNSIFKFKMDHCEFKEKSMASMGFVPFILDFFCTFNTTCYN------KTQINWNENYSSIYAFKMFTKNLYN-VYQTLPKEKLTVNSLITWATNHKFEIDQLISNI-----------------MPIIKLLSPLIASLKEADTE-------NLTASKPIIIQ-IFKVFCGSDENDFTEFYYK--FSSISTKNVSGQTNAGS----QFMNESNVTCERNFENFFGNS---NIFDTISSWVFGKIYFSPNSPLTREIMRRANITFETLDYIRLAS-------IEWRLHFRDWINEAVNNSKLINELKSCKSWYFYFDNNLCETVNAVLNFQTIQSILNKISLMFSLLEKTLNCTELNKFMPINESITVENFIKQPM-----KSVFAVLVINDTFRYLTPSNAT----FLSYQIRIPENQIDSTKHFKVTDKFWTAEPRRETLRDFKYYTSGFLLLQEAIDRAFIEIVTNNETIDVGSSMQIMPYPCYVDDMFIRFITNMMPFMLVIAWVPSVTGLIKSIVYEKERRLKEFMRVMGLGNSVHWIGWFLSTVVVLIFPVTIMXXXXXXXXXXXXXXXXXXXXXXXXXXXXXICQVFMISLFFSNANLASVAGGVIYFILYMPFVVFIRMQSDLSTGFYYLGGLSAQVAFCNAINFIGYWEQSTEGAHFGNLFDGAIIDLKFGVGHCMLMLIVDSVLYLSVAWYVESVFPGQYGVGKAWYFLFTRNYWRAKENISLAHDINNSAQLIIDYDSEGN--FENEYTDLRVGISIRNLVKTY 2346
            F  QL +LLWKNF  ++R+   L+ E+  PL +  I++ VR S   ++   C F  K+M S G +P+I    C  N  C+          +  N + S +  F +  + L   +Y  +  ++  V+ ++    N + E+ + IS I                 MP+++L S  + S  +   E       N+T S   + Q + ++ CG  E    +      +   + K + G+ N       Q+ N +   C    +N   N     I+  +   + GK+ ++P++P+TR I++  + TF  L    L +       + +RL    W    + N  L+   +  +     + N    T     N +T Q+I +        L + + C   +K   ++   T E  I + M     +  +A +V  D       SN T     + Y+IR+  + ++ T   K+ D +W   PR +   D +Y   GF  LQ+ ++ A I  VT +   + G  +Q MPYPCYVDD+F+R ++  +P    +AW+ SV  +IK +VYEKE RLKE MR+MGL +   W+GWF+S+++ L+    ++ ++L   +IL +S    +F  L  + +  I Q F+IS  FS ANLA+  GG+IYF LY+P+V+ +  Q  ++        L + VAF    ++   +E+   G  + NLF       ++ +   +++++ D+VLY  + WY+E+VFPGQ+G+ + WYF  T++YW           + N  QL    +       E E T L++G+SI+NLVK Y
Sbjct:    4 FWTQLGLLLWKNFTYRRRQTFQLLIELAWPLFLFFILISVRRSYPPYEQHECHFPNKAMPSAGTLPWIQGIICNANNPCFRYPTPGESPGVVGNFDKSILQDFLIDNETLSEFLYDNMALDRYKVSEIMDAGVNFE-EVRKQISTIRVLRLQSCTEIETLCLNMPLVQLTS--VKSWSDMRREVLLLSHKNMTGSPQELYQAVSRIVCGHPEGGGLKIKSLNWYEDNNYKYLLGENNTDEEPTPQYDNATTPYCNDLMKNLESNPISRMIWRAMKPLLVGKVLYTPDTPVTRRIIKEVSFTFTYLSGTDLLTKPTTSTYLSYRLAGTSWTASDIYNF-LVKYPEDAQ-----YSNGSAYTWREAYN-ETDQAIQS--------LSRAMECINWDKLEAVS---TEEKLINKSMELLDERKFWAGIVFMDV-----DSNGTEPSEHVKYKIRMDIDNVERTN--KIMDGYWDPGPRADPFEDLRYIWGGFAYLQDIVEHAIIRTVTGSRK-NTGVYVQQMPYPCYVDDLFLRVLSQSLPLFTTLAWIYSVAVIIKGVVYEKEARLKETMRIMGLNSGTLWLGWFISSLIPLLISAALLVIILKEGNILPYSNPLAIFTFLATFGMVTILQCFLISTLFSKANLAAACGGIIYFTLYLPYVLCMAWQEYITYPVKIFASLLSPVAFGFGFDYFSLYEEQGVGVQWHNLFSSPAKGDEYNITTSIVLMVFDAVLYGILTWYIEAVFPGQFGIPRPWYFPVTKSYW-------CGETVKNMKQLQCKQNGTSQIYMEEEPTHLKLGVSIQNLVKVY 779          
BLAST of ATP binding cassette subfamily A member 1 vs. TrEMBL
Match: W5LAQ7 (ATP binding cassette subfamily A member 1 OS=Astyanax mexicanus OX=7994 GN=ABCA1 PE=4 SV=2)

HSP 1 Score: 288.5 bits (737), Expect = 1.203e-78
Identity = 238/827 (28.78%), Postives = 394/827 (47.64%), Query Frame = 1
Query:   91 TKQLKVLLWKNFRLKKRKPITLISEXXXXXXXXXXXXXXRNSIFKFKMDHCEFKEKSMASMGFVPFILDFFCTFNTTCYNKTQI--------NWNE--------NYSSIYAFKMFTKNLYNVYQTLPKEK-LTVNSLITWATNHKFE-IDQLISNIMPIIKLLSPLIASLKE-AD--------TENLTASKPIIIQ-IFKVFCGSDE--------------NDFTEFYYKFSSISTKNVSGQTNAGSQFMNESNVTCERNFENFFGNSNIFDTISSWVFGKIYFSPNSPLTREIMRRANITFETLDYIRLASIEWR-LHFRDW-INEAVNNSKLINELKSCKSWYFYFDNNLCET---VNAVLNFQTIQS--------------ILNKISLMFSLLEKTLNCTELNKFMPINESITVENFIKQPM-----KSVFAVLVINDTFRYLTPSNATFL----SYQIRIPENQIDSTKHFKVTDKFWTAEPRRETLRDFKYYTSGFLLLQEAIDRAFIEIVTNNETIDVGSSMQIMPYPCYVDDMFIRFITNMMPFMLVIAWVPSVTGLIKSIVYEKERRLKEFMRVMGLGNSVHWIGWFLSTVVVLIFPVTIMXXXXXXXXXXXXXXXXXXXXXXXXXXXXXICQVFMISLFFSNANLASVAGGVIYFILYMPFVVFIRMQSDLSTGFYYLGGLSAQVAFCNAINFIGYWEQSTEGAHFGNLFDGAIIDLKFGVGHCMLMLIVDSVLYLSVAWYVESVFPGQYGVGKAWYFLFTRNYWRAKEN-----ISLAHDINNSAQLIIDYDSEGNFENEYTDLRVGISIRNLVKTY 2346
            + QL++LLWKNF  ++R+ + L+ EI+ PL I  I++ VR +   ++   C F  K+M S G +P+I    C  N  C+             N+N+        +   I  +    K+L    + +   K L  N+    A    F+ + +L+   MP+  L+ P +AS++  +D        T N T S   + Q + ++ CG  E              +++   +  ++S   + VS   N  + F N       +N E    +  I+  +   + GKI ++P++P T +I++  N TF+ L  +R     W     + W   E      L+  L        +F   L  T   V  V++F T QS              + N+       + + + C  L+K  P++   T E  I   +     +  +A ++  D       SN++ L    +Y+IR+  + ++ T   K+ D +W   PR +   D +Y   GF  LQ+ I+++ I  VT  +    G  +Q MPYPCYVDD+F+R ++  MP  + +AW+ SV  +IK +VYEKE RLKE MR+MGL N + W  WF+S+++ L+    ++ LLL   ++L +S   VVFL L  + V  I Q F+IS  F+ ANLA+  GG+IYF LY+P+V+ +  Q  +      +  L + VAF     +   +E+   G  + NLF   +    + +   ++++ VD+ +Y  + WY+E+VFPGQYG+ + WYF FT++YW  + +     I      N+ A  I         E E T L +G+ I NLVK Y
Sbjct:    4 STQLRLLLWKNFTYRRRQTLQLLIEIVWPLFIFFILIAVRLNYPPYEQHECHFPNKAMPSAGTLPWIQGIVCNANNPCFRHPTPGESPGVVGNFNDSIISRLFSDAKKILLYSQNDKSLDGFKELIHAVKALQNNTSGKQAVGVTFKSLGKLLE--MPLTSLMFPQLASMRSWSDLRNEILFLTRNATGSPSQMYQAVSRIVCGHPEGGGLKIKSLNWYEDSNYKALFGNYNSSDEEPVSVYDNTSTPFCN----NLMKNMETNPISRMIWRALKPLLMGKILYTPHTPATHKIIKEVNRTFQELGVLRDLGGMWEETRPKAWNFMEHSEEMDLLRTLLQNNVTAAFFSAQLTGTQWSVQDVISFLTKQSEDTRPHGTAFTWRDVFNETDQAIMSISRFMECVNLDKLEPVS---TEEKLINDSLGLLDNRKFWAGIIFPDI-----QSNSSELPPHVNYKIRMDIDNVERTN--KIKDAYWDPGPRADPFEDLRYVWGGFSYLQDVIEQSIIRAVTGTKE-KTGVYIQQMPYPCYVDDIFLRVMSRSMPLFMTLAWMYSVAIIIKGVVYEKEARLKETMRIMGLDNGILWFSWFISSLIPLLMSAGLLVLLLKMGNLLPYSDPGVVFLFLGSFAVVTIMQCFLISTVFARANLAAACGGIIYFTLYLPYVLCVAWQDYIGLPAKVIASLLSPVAFGFGCEYFALFEEQGVGIQWKNLFSSPMEKDDYSLTTSIIIMYVDAFIYGVMTWYIEAVFPGQYGIPRPWYFPFTKSYWFGEGDQRPTPILKGRKANSGAVCI---------EEEPTHLDMGVYIENLVKVY 804          
BLAST of ATP binding cassette subfamily A member 1 vs. TrEMBL
Match: A0A3Q3L2S5 (Zgc:172302 OS=Mastacembelus armatus OX=205130 PE=4 SV=1)

HSP 1 Score: 286.574 bits (732), Expect = 4.606e-78
Identity = 232/806 (28.78%), Postives = 387/806 (48.01%), Query Frame = 1
Query:   88 FTKQLKVLLWKNFRLKKRKPITLISEXXXXXXXXXXXXXXRNSIFKFKMDHCEFKEKSMASMGFVPFILDFFCTFNTTCYNKTQ---------------INWNENYSSIYAFK----MFTKNLYNVYQTLPKEK-LTVNS-----LITWATNHKFEIDQLISNIM----PIIKLLSPLIASLKEADTENLTASKPIIIQIF-KVFCGSDENDFTEF----YYKFSSISTKNVSGQTNAGSQFMNESNVT---CERNFENFFGNSN---IFDTISSWVFGKIYFSPNSPLTREIMRRANITFETLDYIRLASIEWRLHFRDWINEAVNNSKLINELKSCKSWYFYFDNNLCETVNAVLNF-----QTIQSILNKISLMFSLLEKTLNCTELNKFMPINESITVEN-FIKQPM-----KSVFA--VLVINDTFRYLTPSNATFLSYQIRIPENQIDSTKHFKVTDKFWTAEPRRETLRDFKYYTSGFLLLQEAIDRAFIEIVTNNETIDVGSSMQIMPYPCYVDDMFIRFITNMMPFMLVIAWVPSVTGLIKSIVYEKERRLKEFMRVMGLGNSVHWIGWFLSTVVVLIFPVTIMXXXXXXXXXXXXXXXXXXXXXXXXXXXXXICQVFMISLFFSNANLASVAGGVIYFILYMPFVVFIRMQSDLSTGFYYLGGLSAQVAFCNAINFIGYWEQSTEGAHFGNLFDGAIIDLKFGVGHCMLMLIVDSVLYLSVAWYVESVFPGQYGVGKAWYFLFTRNYWRAKENISLAHDINNSAQLIIDYDSEGNFENEYTDLRVGISIRNLVKTY 2346
            F KQL +LLWKN   ++R  I LI E+L PL + +I++ VR+S   +K   C F  K++ S G +P+I    C  N  C++                  +  + N ++ + F+    +F  N +     LP E+ L  N      L+T ++     +DQL+ + +      +   + + A+L+   TEN TA      + F ++ CG  E          +Y+ + I  K+  G+       ++  N T   C+        N     ++  I     GK+ ++PN+P  +++M+  N TFE L  +   +  W       +   + N               Y +++L      ++N       T   I N I+   + L +   C  LNK     E +  E   I + +     + ++A  V ++ +T     P + T   Y+IR+  +  D T+  K+ D+FW   P  +   D +Y   GF+ +Q+ ++RA   ++T  +    G  +Q MPYPCYVDD+F+R +   +P  + +AW+ SV  +IK +VYEKE RLKE MR+MGLG    W+ W +S++V  +    ++  LL +  IL +S   VVF  L+ +  + I Q F+IS FFS ANLA+  GG+IYF LY+P+V+ +  +  L+T    L    + VAF     +   +E+   G  + NL    +    +     ++ML VD+ +Y   AWY+E+VFPG+YG+ + WYF+F  NYW         + +++  +  +  D   + E E T+L +G+SIRNLVK Y
Sbjct:    3 FFKQLTLLLWKNITYRRRNKIQLIIELLWPLFLFVILISVRHSHPPYKQSQCHFPNKALPSAGTLPWIQGIICNINNPCFHSPTPGETPGQVGNFDNSIVQQSMNPANSFCFERSKLLFCVNAFVFTADLPVEEYLRANETFSTFLLTNSSLSPVTVDQLMKSRLNFQFSSLSSFANMSAALRLLSTENRTALPTESFRAFSRIMCGHPEVGGERIPSLNWYEDNDI--KSFLGKNGTEDTDLDHDNSTTPFCKSLIHGLESNPLSRIVWRGIKPLFIGKLLYTPNTPAVQQVMKEVNKTFEDLQILLELNEAWI-----EVGPRIKN---------------YMESSLLSLYRILVNLLPGEPPTWLDIYNDINHTITTLAQITECFSLNKL----EGLETEGQLIDRALVLLEDRQLWAGVVFLLPNTSSLRVPPHVT---YKIRMDID--DVTRTNKIKDRFWDPGPAADPFNDMRYIWGGFVYIQDLVERAVSRVLTGVQQT-TGIYVQQMPYPCYVDDVFLRVLNRSLPLFMTLAWIYSVAMIIKGVVYEKEARLKETMRIMGLGTGTLWLSWLISSMVPFLVSAVLLIALLKWGDILPYSDATVVFFFLMAFATATIMQCFLISTFFSKANLAAACGGLIYFGLYLPYVLCVAWRDHLNTTHRVLASFLSPVAFGFGCEYFSQYEEQGVGIQWYNLRSSPVEGDSYSFTLSIIMLYVDAFIYAIAAWYIEAVFPGEYGIPRPWYFIFQLNYWG-------GYIVSSKCKNCLPSD---HIEPEPTNLILGVSIRNLVKIY 766          
BLAST of ATP binding cassette subfamily A member 1 vs. Ensembl Cavefish
Match: ENSAMXT00000016919.2 (pep primary_assembly:Astyanax_mexicanus-2.0:8:9912642:9956080:1 gene:ENSAMXG00000016432.2 transcript:ENSAMXT00000016919.2 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 288.5 bits (737), Expect = 4.557e-82
Identity = 238/827 (28.78%), Postives = 394/827 (47.64%), Query Frame = 1
Query:   91 TKQLKVLLWKNFRLKKRKPITLISEXXXXXXXXXXXXXXRNSIFKFKMDHCEFKEKSMASMGFVPFILDFFCTFNTTCYNKTQI--------NWNE--------NYSSIYAFKMFTKNLYNVYQTLPKEK-LTVNSLITWATNHKFE-IDQLISNIMPIIKLLSPLIASLKE-AD--------TENLTASKPIIIQ-IFKVFCGSDE--------------NDFTEFYYKFSSISTKNVSGQTNAGSQFMNESNVTCERNFENFFGNSNIFDTISSWVFGKIYFSPNSPLTREIMRRANITFETLDYIRLASIEWR-LHFRDW-INEAVNNSKLINELKSCKSWYFYFDNNLCET---VNAVLNFQTIQS--------------ILNKISLMFSLLEKTLNCTELNKFMPINESITVENFIKQPM-----KSVFAVLVINDTFRYLTPSNATFL----SYQIRIPENQIDSTKHFKVTDKFWTAEPRRETLRDFKYYTSGFLLLQEAIDRAFIEIVTNNETIDVGSSMQIMPYPCYVDDMFIRFITNMMPFMLVIAWVPSVTGLIKSIVYEKERRLKEFMRVMGLGNSVHWIGWFLSTVVVLIFPVTIMXXXXXXXXXXXXXXXXXXXXXXXXXXXXXICQVFMISLFFSNANLASVAGGVIYFILYMPFVVFIRMQSDLSTGFYYLGGLSAQVAFCNAINFIGYWEQSTEGAHFGNLFDGAIIDLKFGVGHCMLMLIVDSVLYLSVAWYVESVFPGQYGVGKAWYFLFTRNYWRAKEN-----ISLAHDINNSAQLIIDYDSEGNFENEYTDLRVGISIRNLVKTY 2346
            + QL++LLWKNF  ++R+ + L+ EI+ PL I  I++ VR +   ++   C F  K+M S G +P+I    C  N  C+             N+N+        +   I  +    K+L    + +   K L  N+    A    F+ + +L+   MP+  L+ P +AS++  +D        T N T S   + Q + ++ CG  E              +++   +  ++S   + VS   N  + F N       +N E    +  I+  +   + GKI ++P++P T +I++  N TF+ L  +R     W     + W   E      L+  L        +F   L  T   V  V++F T QS              + N+       + + + C  L+K  P++   T E  I   +     +  +A ++  D       SN++ L    +Y+IR+  + ++ T   K+ D +W   PR +   D +Y   GF  LQ+ I+++ I  VT  +    G  +Q MPYPCYVDD+F+R ++  MP  + +AW+ SV  +IK +VYEKE RLKE MR+MGL N + W  WF+S+++ L+    ++ LLL   ++L +S   VVFL L  + V  I Q F+IS  F+ ANLA+  GG+IYF LY+P+V+ +  Q  +      +  L + VAF     +   +E+   G  + NLF   +    + +   ++++ VD+ +Y  + WY+E+VFPGQYG+ + WYF FT++YW  + +     I      N+ A  I         E E T L +G+ I NLVK Y
Sbjct:    4 STQLRLLLWKNFTYRRRQTLQLLIEIVWPLFIFFILIAVRLNYPPYEQHECHFPNKAMPSAGTLPWIQGIVCNANNPCFRHPTPGESPGVVGNFNDSIISRLFSDAKKILLYSQNDKSLDGFKELIHAVKALQNNTSGKQAVGVTFKSLGKLLE--MPLTSLMFPQLASMRSWSDLRNEILFLTRNATGSPSQMYQAVSRIVCGHPEGGGLKIKSLNWYEDSNYKALFGNYNSSDEEPVSVYDNTSTPFCN----NLMKNMETNPISRMIWRALKPLLMGKILYTPHTPATHKIIKEVNRTFQELGVLRDLGGMWEETRPKAWNFMEHSEEMDLLRTLLQNNVTAAFFSAQLTGTQWSVQDVISFLTKQSEDTRPHGTAFTWRDVFNETDQAIMSISRFMECVNLDKLEPVS---TEEKLINDSLGLLDNRKFWAGIIFPDI-----QSNSSELPPHVNYKIRMDIDNVERTN--KIKDAYWDPGPRADPFEDLRYVWGGFSYLQDVIEQSIIRAVTGTKE-KTGVYIQQMPYPCYVDDIFLRVMSRSMPLFMTLAWMYSVAIIIKGVVYEKEARLKETMRIMGLDNGILWFSWFISSLIPLLMSAGLLVLLLKMGNLLPYSDPGVVFLFLGSFAVVTIMQCFLISTVFARANLAAACGGIIYFTLYLPYVLCVAWQDYIGLPAKVIASLLSPVAFGFGCEYFALFEEQGVGIQWKNLFSSPMEKDDYSLTTSIIIMYVDAFIYGVMTWYIEAVFPGQYGIPRPWYFPFTKSYWFGEGDQRPTPILKGRKANSGAVCI---------EEEPTHLDMGVYIENLVKVY 804          
BLAST of ATP binding cassette subfamily A member 1 vs. Ensembl Cavefish
Match: abca1a (ATP-binding cassette sub-family A member 1-like [Source:NCBI gene;Acc:103028164])

HSP 1 Score: 254.988 bits (650), Expect = 8.302e-71
Identity = 185/636 (29.09%), Postives = 321/636 (50.47%), Query Frame = 1
Query:  559 TENLTASKPIIIQ-IFKVFCGSDENDFTEF----YYK---FSSISTKNVSGQTNAGSQFMNESNVTCE---RNFENFFGNSNIFDTISSWVFGKIYFSPNSPLTREIMRRANITFETLDYIRLASIEWRLHFRDWINEAVNNSK---LINELKSCKSWYFYFDNNLCET---VNAVLNFQTIQS--------------ILNKISLMFSLLEKTLNCTELNKFMPI-NESITVENFIKQPMKSV-----FAVLVINDTFRYLT--PSNATFLSYQIRIPENQIDSTKHFKVTDKFWTAEPRRETLRDFKYYTSGFLLLQEAIDRAFIEIVTNNETIDVGSSMQIMPYPCYVDDMFIRFITNMMPFMLVIAWVPSVTGLIKSIVYEKERRLKEFMRVMGLGNSVHWIGWFLSTVVVLIFPVTIMXXXXXXXXXXXXXXXXXXXXXXXXXXXXXICQVFMISLFFSNANLASVAGGVIYFILYMPFVVFIRMQSDLSTGFYYLGGLSAQVAFCNAINFIGYWEQSTEGAHFGNLFDGAIIDLKFGVGHCMLMLIVDSVLYLSVAWYVESVFPGQYGVGKAWYFLFTRNYWRAKENISLAHDINNSAQLIIDYDSEG-NFENEYTDLRVGISIRNLVKTY 2346
            T N+T S   + Q + ++ CG  E    +     +Y+   + ++   +   +T   S + N S   C    ++ E+   +  I+  +   + GKI ++P++P T+ I+   N TF+ L  +R     W    R  + + + NS+   L+  L    +   +F+  L  T   V  +  F T  S              + N+       + + + C  L+K  P+ NE    E  + + M+ +     +A +V  D     +  PSN   ++Y+IR+  + ++ T   K+ D +W   PR +   D +Y   GF  LQ+ I+   I  +T ++    G  +Q MPYPCYVDD+F+R ++  MP  + +AW+ SV  +IK +VYEKE RLKE MR+MGL N + W+ WF+S+++ L+    ++ L+L   ++L +S   VV+L L+ + +  I Q F+IS  FS ANLA+  GG+IYF LY+P+V+ +  Q  +  G   +  L + VAF     +   +E+   G  + NL    + +  + +   + +++ D++LY  + WY+E+VFPGQYG+ + WYF FT++YW  ++    +    N  +     ++E    E+  +DL  G+ I NLVK Y
Sbjct:  293 TGNVTRSPNHMYQAVSRIVCGHPEGGGLKIKSLNWYEDNNYKALFGNHNDNETEPMSAYDNTSTPYCNNMMKSLESSPVSRMIWRALKPLLMGKILYTPDTPATQRIIHEVNKTFQQLGVLRDLGGMWE-EMRPKVWDFMENSEEMDLVRTLLQNNASARFFNTKLKGTEWRVEDISRFLTKVSEDTRPPGSAYTWREVFNETDQAIQTISRFMECVNLDKLEPVANE----ERLVNKSMRLLDDRKFWAGIVFPDIKANASEIPSN---VNYKIRMDIDNVERTN--KIKDGYWDPGPRADPFEDLRYVWGGFSYLQDVIEHGIIRALTGSKE-KTGVYIQQMPYPCYVDDIFLRVMSRSMPLFMTLAWMYSVAIIIKGVVYEKEARLKETMRIMGLDNGILWLSWFISSLIPLLISAALLVLILKMGNLLPYSDPGVVYLFLVSFAIVTIMQCFLISTIFSRANLAAACGGIIYFTLYLPYVLCVAWQDYVGFGAKVVVSLLSPVAFGFGCEYFALFEEQGVGIQWSNLLSSPLEEDSYSLTTSISLMLFDALLYAVMTWYIEAVFPGQYGIPRPWYFPFTKSYWCGEKCGWTSAQTTNKRE-----NAEAFCIEDVPSDLEPGVYIENLVKVY 912          
BLAST of ATP binding cassette subfamily A member 1 vs. Ensembl Cavefish
Match: abca1a (ATP-binding cassette sub-family A member 1-like [Source:NCBI gene;Acc:103028164])

HSP 1 Score: 254.988 bits (650), Expect = 8.302e-71
Identity = 185/636 (29.09%), Postives = 321/636 (50.47%), Query Frame = 1
Query:  559 TENLTASKPIIIQ-IFKVFCGSDENDFTEF----YYK---FSSISTKNVSGQTNAGSQFMNESNVTCE---RNFENFFGNSNIFDTISSWVFGKIYFSPNSPLTREIMRRANITFETLDYIRLASIEWRLHFRDWINEAVNNSK---LINELKSCKSWYFYFDNNLCET---VNAVLNFQTIQS--------------ILNKISLMFSLLEKTLNCTELNKFMPI-NESITVENFIKQPMKSV-----FAVLVINDTFRYLT--PSNATFLSYQIRIPENQIDSTKHFKVTDKFWTAEPRRETLRDFKYYTSGFLLLQEAIDRAFIEIVTNNETIDVGSSMQIMPYPCYVDDMFIRFITNMMPFMLVIAWVPSVTGLIKSIVYEKERRLKEFMRVMGLGNSVHWIGWFLSTVVVLIFPVTIMXXXXXXXXXXXXXXXXXXXXXXXXXXXXXICQVFMISLFFSNANLASVAGGVIYFILYMPFVVFIRMQSDLSTGFYYLGGLSAQVAFCNAINFIGYWEQSTEGAHFGNLFDGAIIDLKFGVGHCMLMLIVDSVLYLSVAWYVESVFPGQYGVGKAWYFLFTRNYWRAKENISLAHDINNSAQLIIDYDSEG-NFENEYTDLRVGISIRNLVKTY 2346
            T N+T S   + Q + ++ CG  E    +     +Y+   + ++   +   +T   S + N S   C    ++ E+   +  I+  +   + GKI ++P++P T+ I+   N TF+ L  +R     W    R  + + + NS+   L+  L    +   +F+  L  T   V  +  F T  S              + N+       + + + C  L+K  P+ NE    E  + + M+ +     +A +V  D     +  PSN   ++Y+IR+  + ++ T   K+ D +W   PR +   D +Y   GF  LQ+ I+   I  +T ++    G  +Q MPYPCYVDD+F+R ++  MP  + +AW+ SV  +IK +VYEKE RLKE MR+MGL N + W+ WF+S+++ L+    ++ L+L   ++L +S   VV+L L+ + +  I Q F+IS  FS ANLA+  GG+IYF LY+P+V+ +  Q  +  G   +  L + VAF     +   +E+   G  + NL    + +  + +   + +++ D++LY  + WY+E+VFPGQYG+ + WYF FT++YW  ++    +    N  +     ++E    E+  +DL  G+ I NLVK Y
Sbjct:  293 TGNVTRSPNHMYQAVSRIVCGHPEGGGLKIKSLNWYEDNNYKALFGNHNDNETEPMSAYDNTSTPYCNNMMKSLESSPVSRMIWRALKPLLMGKILYTPDTPATQRIIHEVNKTFQQLGVLRDLGGMWE-EMRPKVWDFMENSEEMDLVRTLLQNNASARFFNTKLKGTEWRVEDISRFLTKVSEDTRPPGSAYTWREVFNETDQAIQTISRFMECVNLDKLEPVANE----ERLVNKSMRLLDDRKFWAGIVFPDIKANASEIPSN---VNYKIRMDIDNVERTN--KIKDGYWDPGPRADPFEDLRYVWGGFSYLQDVIEHGIIRALTGSKE-KTGVYIQQMPYPCYVDDIFLRVMSRSMPLFMTLAWMYSVAIIIKGVVYEKEARLKETMRIMGLDNGILWLSWFISSLIPLLISAALLVLILKMGNLLPYSDPGVVYLFLVSFAIVTIMQCFLISTIFSRANLAAACGGIIYFTLYLPYVLCVAWQDYVGFGAKVVVSLLSPVAFGFGCEYFALFEEQGVGIQWSNLLSSPLEEDSYSLTTSISLMLFDALLYAVMTWYIEAVFPGQYGIPRPWYFPFTKSYWCGEKCGWTSAQTTNKRE-----NAEAFCIEDVPSDLEPGVYIENLVKVY 912          
BLAST of ATP binding cassette subfamily A member 1 vs. Ensembl Cavefish
Match: abca1a (ATP-binding cassette sub-family A member 1-like [Source:NCBI gene;Acc:103028164])

HSP 1 Score: 254.603 bits (649), Expect = 9.367e-71
Identity = 185/636 (29.09%), Postives = 321/636 (50.47%), Query Frame = 1
Query:  559 TENLTASKPIIIQ-IFKVFCGSDENDFTEF----YYK---FSSISTKNVSGQTNAGSQFMNESNVTCE---RNFENFFGNSNIFDTISSWVFGKIYFSPNSPLTREIMRRANITFETLDYIRLASIEWRLHFRDWINEAVNNSK---LINELKSCKSWYFYFDNNLCET---VNAVLNFQTIQS--------------ILNKISLMFSLLEKTLNCTELNKFMPI-NESITVENFIKQPMKSV-----FAVLVINDTFRYLT--PSNATFLSYQIRIPENQIDSTKHFKVTDKFWTAEPRRETLRDFKYYTSGFLLLQEAIDRAFIEIVTNNETIDVGSSMQIMPYPCYVDDMFIRFITNMMPFMLVIAWVPSVTGLIKSIVYEKERRLKEFMRVMGLGNSVHWIGWFLSTVVVLIFPVTIMXXXXXXXXXXXXXXXXXXXXXXXXXXXXXICQVFMISLFFSNANLASVAGGVIYFILYMPFVVFIRMQSDLSTGFYYLGGLSAQVAFCNAINFIGYWEQSTEGAHFGNLFDGAIIDLKFGVGHCMLMLIVDSVLYLSVAWYVESVFPGQYGVGKAWYFLFTRNYWRAKENISLAHDINNSAQLIIDYDSEG-NFENEYTDLRVGISIRNLVKTY 2346
            T N+T S   + Q + ++ CG  E    +     +Y+   + ++   +   +T   S + N S   C    ++ E+   +  I+  +   + GKI ++P++P T+ I+   N TF+ L  +R     W    R  + + + NS+   L+  L    +   +F+  L  T   V  +  F T  S              + N+       + + + C  L+K  P+ NE    E  + + M+ +     +A +V  D     +  PSN   ++Y+IR+  + ++ T   K+ D +W   PR +   D +Y   GF  LQ+ I+   I  +T ++    G  +Q MPYPCYVDD+F+R ++  MP  + +AW+ SV  +IK +VYEKE RLKE MR+MGL N + W+ WF+S+++ L+    ++ L+L   ++L +S   VV+L L+ + +  I Q F+IS  FS ANLA+  GG+IYF LY+P+V+ +  Q  +  G   +  L + VAF     +   +E+   G  + NL    + +  + +   + +++ D++LY  + WY+E+VFPGQYG+ + WYF FT++YW  ++    +    N  +     ++E    E+  +DL  G+ I NLVK Y
Sbjct:  292 TGNVTRSPNHMYQAVSRIVCGHPEGGGLKIKSLNWYEDNNYKALFGNHNDNETEPMSAYDNTSTPYCNNMMKSLESSPVSRMIWRALKPLLMGKILYTPDTPATQRIIHEVNKTFQQLGVLRDLGGMWE-EMRPKVWDFMENSEEMDLVRTLLQNNASARFFNTKLKGTEWRVEDISRFLTKVSEDTRPPGSAYTWREVFNETDQAIQTISRFMECVNLDKLEPVANE----ERLVNKSMRLLDDRKFWAGIVFPDIKANASEIPSN---VNYKIRMDIDNVERTN--KIKDGYWDPGPRADPFEDLRYVWGGFSYLQDVIEHGIIRALTGSKE-KTGVYIQQMPYPCYVDDIFLRVMSRSMPLFMTLAWMYSVAIIIKGVVYEKEARLKETMRIMGLDNGILWLSWFISSLIPLLISAALLVLILKMGNLLPYSDPGVVYLFLVSFAIVTIMQCFLISTIFSRANLAAACGGIIYFTLYLPYVLCVAWQDYVGFGAKVVVSLLSPVAFGFGCEYFALFEEQGVGIQWSNLLSSPLEEDSYSLTTSISLMLFDALLYAVMTWYIEAVFPGQYGIPRPWYFPFTKSYWCGEKCGWTSAQTTNKRE-----NAEAFCIEDVPSDLEPGVYIENLVKVY 911          
BLAST of ATP binding cassette subfamily A member 1 vs. Ensembl Cavefish
Match: abca4a (retinal-specific ATP-binding cassette transporter-like [Source:NCBI gene;Acc:103024609])

HSP 1 Score: 250.366 bits (638), Expect = 2.442e-69
Identity = 183/659 (27.77%), Postives = 328/659 (49.77%), Query Frame = 1
Query:  487 QLISNIMPIIKLLSPLIASLKEADTENLTASKPIIIQIFKVFCGSDENDFTEF----------YYKFSSISTKNVSGQ---TNAGSQFMNESNVTCERNFENFFGNSNIFDTISSWVFGKIYFSPNSPLTREIMRRANITFETLDYIRLASIEWR---LHFRDWINEAVNNSKLINELKSCKSWYFYFDNNLCET---VNAVLNFQTIQSILNKISLM--------FSLLEKTLN-------CTELNKF--MPINESITVENFIKQPMKSVFAVLVINDTFRYLTPSNATFLSYQIRIPENQIDSTKHFKVTDKFWTAEPRRETLRDFKYYTSGFLLLQEAIDRAFIEIVTNNETIDVGSSMQIMPYPCYVDDMFIRFITNMMPFMLVIAWVPSVTGLIKSIVYEKERRLKEFMRVMGLGNSVHWIGWFLSTVVVLIFPVTIMXXXXXXXXXXXXXXXXXXXXXXXXXXXXXICQVFMISLFFSNANLASVAGGVIYFILYMPFVVFIRMQSDLSTGFYYLGGLSAQVAFCNAINFIGYWEQSTEGAHFGNLFDGAIIDLKFGVGHCMLMLIVDSVLYLSVAWYVESVFPGQYGVGKAWYFLFTRNYWRAKENISLAHDINNSAQLIIDYDSEGNFENEYTDLRVGISIRNLVKTYPGA 2355
            +L+   + ++++L PL  S       +L A+   ++      CG  E  F+            Y  F  I+      Q    ++ + F N+      ++ E+      +++T+  ++ GKI ++P+SP  R++++ AN TFE L+ +R     W        D+    +    L + L++  S   Y D  L  T   +  +LNF    S   +   M        F+L ++TL        C  L+KF  +P    +T +       K  +A LV  DTF + T      + ++IR+  + ++ T   K+ D++W   PR + + D +Y   GF  LQ+ ++ A I+  T  E   +G  +Q MPYPCYVDD+F+  ++   P  +V+AWV SV+ ++KS+V EKE RLKE ++ MG+ N V W  WF+ + +V+     +++ +++   +L++S   ++F+ LL +  + I Q F++++FF+ ANLA+   G++YF  Y+P +     Q  ++     +  L +QVAF     ++  +E+   G  + N+    +   +F     ++M+++D+VLY  +AWY++SVFPGQYG+G+ +YF    +Y   K      H + +S         +  FE E + L VG+ + NLVK + G+
Sbjct:  285 RLVRMSVELVQVLQPLFQSPGNPSFSHLMAAASSLV------CGYTEGAFSRVTSFNWYEDNNYKAFLGINNSRAQAQHTYDSSTTAFCND----VMKDLESSPATRLMWNTLKPFLMGKILYAPDSPAIRQLIKNANSTFEELERLRNIIRSWEEVGPQLWDFFQSNIQLDVLRDILRN-PSVMDYMDRGLKNTGLTIRHILNFLHTGSEEERERDMVQFDWRNIFNLTDRTLRMINQYGECLVLDKFVGLPDETQLTQKALDLIAEKKFWAGLVFVDTFSWTT-KIPPHIKFKIRMDIDTVERTN--KIKDRYWDPGPRADPMDDLRYVWGGFAYLQDMVEHAVIKTHTGKE-WPLGVYLQQMPYPCYVDDLFMLTLSRCFPIFIVLAWVYSVSMMVKSVVLEKEMRLKETLKAMGVTNEVLWCAWFIDSFLVMAASTALLTAIIMGGKVLNYSNPIILFIFLLTFTTATIMQCFLMTVFFNKANLAAACSGILYFSFYLPHLACFTWQDRITKDMKIMASLMSQVAFGFGTEYLSRYEEQGLGLQWDNIHTSPLEGDEFSFHTSIIMMLLDTVLYAVLAWYLDSVFPGQYGIGRPFYFPIQPSYCSLK-----PHALVSSPP-----TEKVFFEAEPSGLVVGVHVENLVKVFSGS 918          
BLAST of ATP binding cassette subfamily A member 1 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000002495.1 (pep scaffold:Pmarinus_7.0:GL480265:53:27909:1 gene:ENSPMAG00000002218.1 transcript:ENSPMAT00000002495.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 221.476 bits (563), Expect = 1.001e-60
Identity = 126/371 (33.96%), Postives = 203/371 (54.72%), Query Frame = 1
Query: 1252 LSYQIRIPENQIDSTKHFKVTDKFWTAEPRRETLRDFKYYTSGFLLLQEAIDRAFIEIVTNNETIDVGSSMQIMPYPCYVDDMFIRFITNMMPFMLVIAWVPSVTGLIKSIVYEKERRLKEFMRVMGLGNSVHWIGWFLSTVVVLIFPVTIMXXXXXXXXXXXXXXXXXXXXXXXXX----XXXXICQVFMISLFFSNANLASVAGGVIYFILYMPFVVFIRMQSDLSTGFYYLGGLSAQVAFCNAINFIGYWEQSTEGAHFGNLFDGAIIDLKFGVGHCMLMLIVDSVLYLSVAWYVESVFPGQYGVGKAWYFLFTRNYWRAKENISLAHDI--NNSAQLIIDYDSEGNFENEYTDLRVGISIRNLVKTY 2346
            + Y+IR+  + +  T   K+ D++W   PR +   D +Y   GF  LQ+++++  I   TN  ++ VG  +Q MPYPCYVDD+F+R +   +P  L +AW+ SV  ++K +V+EKE RLKE MR+MGL  S+ W+ WF+S ++ L+    ++++LL     L    +     ++ LY     ++ + Q F+IS FFS ANLA+  GG++YF  Y+P+V+ +  Q+ ++        + + VAF     F   +E+   G  + N+F   +    +     + M++ D+ +Y  +  Y+E+VFPGQYGV K WYF  TR YWR        ++       Q I         E+E  DL VG+SI+ LVK Y
Sbjct:    5 VRYKIRMDIDSVQRTN--KIKDRYWDPGPRADPFDDLRYIWGGFAYLQDSVEQGIIRAQTNG-SLSVGVYVQQMPYPCYVDDIFLRIMNRSLPMFLTLAWMYSVAMILKEVVHEKEARLKETMRIMGLSTSMLWLSWFISILIPLLISAMLLTVLLKVREQLGNILYYSDPTIVYLYLCVFAIATVMQCFLISTFFSRANLAAATGGIVYFSFYLPYVLCVAWQNQITYSVKISTSIFSTVAFSFGSEFFSLYEEQGVGMQWENVFSSPVEGEDYTFISSIFMMLFDAFVYGLLTVYIENVFPGQYGVPKPWYFPCTRAYWRGDTMEKELYETIAQKQPQAITGVPDNIYVEDEPGDLPVGVSIQGLVKIY 372          
BLAST of ATP binding cassette subfamily A member 1 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000004117.1 (pep scaffold:Pmarinus_7.0:GL489716:190:6182:-1 gene:ENSPMAG00000003765.1 transcript:ENSPMAT00000004117.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 164.081 bits (414), Expect = 8.252e-44
Identity = 118/367 (32.15%), Postives = 196/367 (53.41%), Query Frame = 1
Query: 1258 YQIRIPENQIDSTKHFKVTDKFWTAEPRRETLRDFKYYTSGFLLLQEAIDRAFIEIVTNNETIDVGSSMQIMPYPCYVDDMFIRFITNMMPFMLVIAWVPSVTGLIKSIVYEKERRLKEFMRVMGLGNSVHWIGWFLSTVVVLIFPVTIMXXXXXXXXXXXXXXXXXXXXXXXXXXXXXICQVFMISLFFSNANLASVAGGVIYFILYMPFV-VFIR--MQSDLSTGF-YYLGGLSAQVAFCNAINFIGYWEQSTEGAHFGNLFDGAIIDLKFGVGHCMLMLIVDSVLYLSVAWYVESVFPGQYGVGKAWYFLFTRNYWRAKENISLAHDINNSAQLIIDYDSEGNFENEYTDLRVGISIRNLVKTY 2346
            Y+IR  +N   + K  ++   +W   P       F Y   GF+ +Q+ I+RA I     ++ ++ G+ +Q+ PYPCY  D F+  I +MMP  +VI+WV SV  +I+ IV EKE RLKE M++MGL N+V W+ WF++  + L   V +++++L Y  +L  S   +++L L +Y ++ +   F++S+ +S A +A+  GG++YF+ Y+P++ V IR  +  D  T F   +  L +  AF     +   +E +  G  +       +    F +   +LML++DSV+Y  + WY+E+V PG YG+ + WYF   R+YW               A     Y++ G  E E T L + + I  L K Y
Sbjct:    7 YKIR--QNSSFTEKTNEIRRAYWRPGPNSGGQYYFFY---GFVWIQDMIERAIINTFVGHDVVEPGNYVQLFPYPCYTRDDFLFVIEHMMPLCMVISWVYSVAMMIQHIVAEKEHRLKEVMKMMGLSNAV-WVAWFITGFLQLSITVAVLTVILKYGQVLMHSDIFIIWLFLTIYALATVMFCFLVSVLYSKARMAAACGGIMYFLSYVPYMYVAIREEVAHDKITAFEKCIASLMSTTAFGLGAKYFALYEVAGVGIQWHTFRQSPVEGDDFNLSLALLMLLLDSVVYGVLTWYIEAVHPGTYGLPRPWYFPLQRSYWLGSG--------RADAWEWSGYEARG-MEKEPTHLPLVVCIERLTKVY 358          
BLAST of ATP binding cassette subfamily A member 1 vs. Ensembl Sea Lamprey
Match: abca12 (ATP-binding cassette, sub-family A (ABC1), member 12 [Source:ZFIN;Acc:ZDB-GENE-030131-9790])

HSP 1 Score: 132.88 bits (333), Expect = 7.150e-32
Identity = 108/403 (26.80%), Postives = 188/403 (46.65%), Query Frame = 1
Query: 1243 ATFLSYQIRIPENQIDSTKHFKVTDKFWTAEPRRETLRDFKYYTSGFLLLQEAIDRAFIEIVTNNETIDVGSSMQIMPYPCYVDDMFIRFITNMMPFMLVIAWVPSVTGLIKSIVYEKERRLKEFMRVMGLGNSVHWIGWFLSTVVVLIFPVTIMXXXXXXXXXXXXXXXXXXXXXXXXXXXXXICQVFMISLFFSNANLASVAGGVIYFILYMPFVV-------FIRMQSDL-------STGFYYLGGLSAQVAFCNAINFIGYWEQSTEGAHFGNLFDGAIIDLKFGVGHCMLMLIVDSVLYLSVAWYVESVFPGQYGVGKAWYFLFTRNYWRA------KENISLAHDINNSAQLII---------------DYDSEGNFENEYTDLRVGISIRNLVKTY 2346
            AT L+Y +R+    +  T + +  D  W   P   T +++ YYT  FL  +  ++RA I +       +    +Q MPYPCY DD F+  +  M P + +IAW+ ++   +K +V EKE   +E+M +MG+  + H++ W L + V+L+  V +++++L  S  L    +A++  + L + +S +   +M+S  F++ N+AS+    IY + + PF+          R Q  L        T F Y   L  Q   C  +  +  W        FG+       D+ F   +   MLI+D+ +Y  + WY+ +V+PG YG+ + +YFLFTR   +A      K    +   + +  + ++               D       E    DL  G+S+R+L K Y
Sbjct:    2 ATHLNYTLRLSIQNVMRTDYLR--DLVWVPGP--HTNQNYMYYTHAFLS-RTMLERAAISLYIGRNISEPALQVQPMPYPCYTDDSFLHSVGLMFPILFMIAWILTIASTVKFLVQEKELCQQEYMNIMGVRPASHFLSWLLQSCVLLLLMVILLTVILKASGTLPSINWALLLALFLCFGISVLAMGYMLSACFTHTNVASLTACFIYLLSFFPFLALSSLTLKLTRWQKSLIVRCLLSPTAFSYATNLITQHCTCIPMRALVQWSNMYHSPLFGD-------DVSF--AYLCWMLIIDTAIYFILGWYIRNVYPGTYGLARPFYFLFTRISSKAHGIPGQKHGSRVIRGLQDGRKGVLRGVTECSCTSPLGAPDGSMRPQLEAVPADLTAGVSLRSLTKQY 390          
BLAST of ATP binding cassette subfamily A member 1 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000001954.1 (pep scaffold:Pmarinus_7.0:GL484253:245:9303:-1 gene:ENSPMAG00000001774.1 transcript:ENSPMAT00000001954.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 80.4925 bits (197), Expect = 7.744e-17
Identity = 42/119 (35.29%), Postives = 67/119 (56.30%), Query Frame = 1
Query: 1336 PRRETLRD---FKYYTSGFLLLQEAIDRAFIEIVTNNETIDVGSS-------MQIMPYPCYVDDMFIRFITNMMPFMLVIAWVPSVTGLIKSIVYEKERRLKEFMRVMGLGNSVHWIGW 1662
            PR   ++D     YY  GFL  Q  ID    E +T      +GS+       +Q  PYP Y DD+FI  I   +P +L++++V +   +++++V+EKE +LKE+M++M L N +HW  W
Sbjct:  117 PRERHMKDGGTPGYYREGFLATQRFID----EAITAAAAERLGSAAPRTAVEVQRFPYPPYRDDIFILAIQTQLPLLLMLSFVYTALNIVRTLVHEKESKLKEYMKMMCLSNWLHWTAW 231          
BLAST of ATP binding cassette subfamily A member 1 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000001952.1 (pep scaffold:Pmarinus_7.0:GL484253:245:9555:-1 gene:ENSPMAG00000001774.1 transcript:ENSPMAT00000001952.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 80.4925 bits (197), Expect = 1.967e-16
Identity = 42/119 (35.29%), Postives = 67/119 (56.30%), Query Frame = 1
Query: 1336 PRRETLRD---FKYYTSGFLLLQEAIDRAFIEIVTNNETIDVGSS-------MQIMPYPCYVDDMFIRFITNMMPFMLVIAWVPSVTGLIKSIVYEKERRLKEFMRVMGLGNSVHWIGW 1662
            PR   ++D     YY  GFL  Q  ID    E +T      +GS+       +Q  PYP Y DD+FI  I   +P +L++++V +   +++++V+EKE +LKE+M++M L N +HW  W
Sbjct:  201 PRERHMKDGGTPGYYREGFLATQRFID----EAITAAAAERLGSAAPRTAVEVQRFPYPPYRDDIFILAIQTQLPLLLMLSFVYTALNIVRTLVHEKESKLKEYMKMMCLSNWLHWTAW 315          
BLAST of ATP binding cassette subfamily A member 1 vs. Ensembl Nematostella
Match: EDO46878 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RNL9])

HSP 1 Score: 225.713 bits (574), Expect = 1.308e-61
Identity = 129/370 (34.86%), Postives = 213/370 (57.57%), Query Frame = 1
Query: 1252 LSYQIRIPENQIDSTKHF-KVTDKFWTAEPRRETLRDFKYYTSGFLLLQEAIDRAFIEIVTNNETIDVGSSMQIMPYPCYVDDMFIRFITNMMPFMLVIAWVPSVTGLIKSIVYEKERRLKEFMRVMGLGNSVHWIGWFLSTVVVLIFPVTIMXXXXXXXXXXXXXXXXXXXXXXXXXXXXXICQVFMISLFFSNANLASVAGGVIYFILYMPFVVFIRMQSDLSTGFYYLGGLSAQVAFCNAINFIGYWEQSTEGAHFGNLFDGAIIDLKFGVGHCMLMLIVDSVLYLSVAWYVESVFPGQYGVGKAWYFLFTRNYWRAKENISLAHDINNSAQLIIDYDSEGN----FENEYTDLRVGISIRNLVKTY 2346
            + Y+IR     +D T    ++ D +W   P     +   Y   GF+ LQ+ IDRA + I  N    + G+  Q+ PYPCY+ D F+ +I   MP  + +AW+ +   +IKSIVYEKE+RLKE M+VMGLG +VHW+ WF+++   ++  +  + + L    IL  S   ++FL L++++ + I   F+IS+FFS AN+++  GG+I+F+ Y+P+ +    ++ +++       LS+  AF  A N++  +E+   GA + NL+   I   +F +G+ M M+++D VLY    +Y+E+V PGQYG+ + WYF   ++YW  ++  S   D+++ A      D   N     E E + L +G+SIRNLVK Y
Sbjct:   20 IKYKIR---QDVDFTPRTDRIRDWYWRPGPNGWFSKQ-GYMNFGFVFLQDMIDRALLTISFNETVFEPGTYAQMFPYPCYIRDRFVFYIGGTMPLFMTLAWIYTAAMIIKSIVYEKEKRLKEVMKVMGLGRTVHWVAWFINSASTMLITIIFLVITLKAGRILQHSDPFIIFLFLVVFMFATIMMCFLISVFFSRANVSAACGGIIFFVTYLPYTMVRWFEAFMNSSQIAAACLSSTTAFGVACNYLARYEEQGVGAQWNNLYASPIAGDEFSLGYAMGMMMIDGVLYALATFYIEAVMPGQYGIPRPWYFPLQKSYWFPQKPAS--PDMDDVA---FSPDGATNNDVAMETEPSHLSMGVSIRNLVKIY 380          
BLAST of ATP binding cassette subfamily A member 1 vs. Ensembl Nematostella
Match: EDO38879 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SBQ0])

HSP 1 Score: 197.208 bits (500), Expect = 2.793e-52
Identity = 155/555 (27.93%), Postives = 274/555 (49.37%), Query Frame = 1
Query:  805 KIYFSPNSPLTREIMRRANITFETLDYIRLASIEWRLHFRDWINEAVNNSK-------LINELKSCKSWYFYFDNNLCE---TVNAVLNFQTIQSILNK--------------ISLMFSLLEKTLNCTELNKFMPIN--ESITVENFIKQPMKSV-FAVLVINDTFRYLTPSNA--TFLSYQIRIPENQIDSTKHFKVTDKFWTAEPRRETLRDFKYYTSGFLLLQEAIDRAFIEIVTNNETIDVGSSMQIMPYPCYVDDMFIRFITNMMPFMLVIAWVPSVTGLIKSIVYEKERRLKEFMRVMGLGNSVHWIGWFLSTVVVLIFPVTIMXXXXXXXXXXXXXXXXXXXXXXXXXXXXXICQVFMISLFFSNANLASVAGGVIYFILYMPFV-VFIR---MQSDLSTGFYYLGGLSAQVAFCNAINFIGYWEQSTEGAHFGNLFDGAIIDLKFGVGHCMLMLIVDSVLYLSVAWYVESVFPGQYGVGKAWYFLFTRNYWRAKENISLAHDINNSAQLIIDYDSEGN--------FENEYTDLRVGISIRNLVKTY 2346
            KI ++PN+    ++++ AN TF  ++Y++  + +W L+    I  A+  ++       + N +++    Y+   + + E   T +A   F+ I S+L K              I  +  +  +     +L+ F+     ES+    F    ++    + +V    F  + P+      ++Y+IR+           ++ D +W   P+        YY  GF+ LQ+ I+RA + +    E I     +  MPYPCY  D F+  I +MMP  L ++W+ +V  +++SIVYEKE+RLKE M++MGL N VHW+ WF+++V V+   V +++++L Y  +L+FS   +++L L+L+ +  I   F+IS FFS A LA+  GG+IYF+ YMPFV V IR     + + +       L +  AF     +   +E+  EG  + N+    I    F +   +  L+ D+ LY+ + WY+E+V PG YG+ + WYF     YW      +  +    + +++   + E +        +E E   L +G++I NL K Y
Sbjct:   65 KILYAPNNTAADDVIKDANRTFSDIEYLQDLAHDW-LNTSSQIRRALLQNETQFYLGLVSNYIRAYPDSYWELISGISEKDPTTHAPY-FKNIHSLLTKKNGGVNPIIEQLDRIDAVLKIWIEQTKAFKLDIFVGFKDEESLVRYAFNTSGVRGDDSSKIVAGIVFTNIEPNKTLPVHVTYKIRMNATYFTPATD-RIRDSYWRPGPQSWGQ---SYYDLGFVWLQDKIERAVVNLHAMREVIKPAVYLHEMPYPCYSKDRFMLVIQHMMPLCLTVSWIYTVAIVVRSIVYEKEQRLKEVMKMMGLSNVVHWVAWFITSVSVMSITVMLLTVILKYGKVLAFSDPLIIWLSLMLFAIVTIVFCFLISAFFSKAKLAAACGGIIYFLTYMPFVFVSIREGAAHATIESSEKMAISLLSTSAFGLGARYFALYEEQGEGVQWSNIGKSPIRGDDFNLLKVLYFLVFDTFLYVILVWYIEAVHPGSYGLPRPWYFPIQPTYWFGHNTNACPNLRKKNYRMMTSDEMEDSPQTPGLLAYEREPVHLPLGVTIDNLQKVY 613          
BLAST of ATP binding cassette subfamily A member 1 vs. Ensembl Nematostella
Match: EDO48951 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RI12])

HSP 1 Score: 153.68 bits (387), Expect = 3.467e-38
Identity = 137/446 (30.72%), Postives = 227/446 (50.90%), Query Frame = 1
Query: 1072 ISLMFSLLEKTLNCTELNKFMPINESIT-VENFIKQPM----KSVFAVLVINDTFRYLTPSNATFLSYQIRIPENQIDSTKHFKVTDKFWTAEPRRETL--RDFKYYT-SGFLLLQEAIDRAFIEIVTNNETIDVGSSMQI--MPYPCYVDDMFIRFITNMMPFMLVIAWVPSVTGLIKSIVYEKERRLKEFMRVMGLGNSVHWIGWFLSTVVVLIFPVTIMXXXXXXXXXXXXXXXXXXXXXXXXXXXXXICQVFMISLFFSNANLASVAGGVIYFILYMPFVVFIRMQSDLSTGFYYLGGLSAQVAFCNAIN--------FIGYWEQSTEGAHFGNLFDGAIIDLKFGVGHCMLMLIVDSVLYLSVAWYVESVFPGQYGVGKAWYFLFTRNYWRAKENISLAHDINNSAQLIIDYDSEGNFENEYTDLRVGISIRNLVKTYPGA 2355
            +S + S +  T+N   +N+ M  N+  T VE  + +      K + AV+   +  +   P     + Y +R+P +     K ++    +    P  + +  R   +YT SGF +LQ AID A I+    +        M I  +PYP YV D F++ + N++P +L +A++ S   +IK +V+EK++RLKE M++MGL N +HW  WF+  ++ L F + I+++ +    I  FS   VVFL  L Y++S I   F IS+FFSN  L+ + G V+++   +P+ +  + ++      Y     SA+ + C   N         I   E    GA F NL      D  F +   + M+I+ S++YL + WY+ +VFPGQYG+ K +YF F ++YW        +HD    A L     +    E+E TDL +G+ I++L K + G+
Sbjct:   86 VSGLMSSVASTMNIKVVNRSMVHNKDWTSVEQMVAEVAEHEDKYLAAVVFDVEKDKLSLPK---VVKYTLRMPHSSAGERKTWRTERTY----PNFQGIGARTTNFYTFSGFAILQYAIDMAIIQ-AKASLPFPFAYPMNIKQLPYPGYVQDFFVQTVANLLPLLLTLAFIYSAVSIIKELVFEKQQRLKESMKMMGLSNWIHWSAWFIKCLLFLGFTIIIITIFVKVLKIFEFSNGIVVFLFFLCYIISMISYCFFISVFFSNPTLSMLFGSVLWYAALLPYQLLAQNEN------YDTLSQSAKASMCLLPNTCLGIGATLIARLEGFKTGASFSNLASSPSADDHFSLAWVLGMMIISSLVYLILTWYISTVFPGQYGIPKPFYFPFMKSYW-----CGFSHDDVVEAGL-ERVKNNPAIEDEPTDLAIGVQIKDLRKVFKGS 511          
BLAST of ATP binding cassette subfamily A member 1 vs. Ensembl Nematostella
Match: EDO32070 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SW56])

HSP 1 Score: 97.4413 bits (241), Expect = 3.332e-21
Identity = 104/339 (30.68%), Postives = 170/339 (50.15%), Query Frame = 1
Query: 1363 KYYTSGFLLLQEAIDRAFIEIVTNNETIDVGS-SMQIMPYPCYVDDMFIRFITNMMPFMLVIAWVPSVTGLIKSIVYEKERRLKEFMRVMGLGNSVHWIGWFLSTVVVLIFPVTIMXXXXXXXXXXXXXXXXXXXXXXXXXXXXXICQVFMISLFFSNANLASVAGGVIYFILYMPFVVFIRMQSDLSTGFY--YLGGLSAQVAFCNAINFIGYWEQSTEGAHFGNLFDGAIIDLKFGVGHCMLMLIVDSVLYLSVAWYVESVFPGQYGVGKAWYFLFTRNYWRA---KENISL-AHDINNSAQLIIDYDSEGNFENEYTDL--RVGISIRNLVKTYPG 2352
            KY       LQ +ID A  ++V N     V + ++Q+MP   +   +  + I  ++P  +V+A+ P +T L+ ++V EK+ + KE MR+MG+ ++ +W+ WFL+  +V++    IM  + + +     S + V+ +V  LY +S I   FM+S  F N   A    G I  +    F V I   +  S   Y  +L  + +  AF  A+N      +   GA F NL         F V +C++MLIVD +LYL +A Y+++V P +YG  +  YF+F  ++W+    +   SL AH +         Y SE + E    ++  R  ISI NL K +PG
Sbjct:    8 KYLIYNTTTLQASIDAAISKVVANLPFYIVPNITVQMMPKAQFTPSL--QGIQTIVPIYMVLAFSPYITILVINLVREKQEKHKELMRIMGMVDTAYWLSWFLTYAIVVLIACLIMVTVSVIAGFFGESNYLVLLIVFYLYGLSIIMLSFMMSPLFKNPKTA----GFIASLFTAIFAVLIIPLTGPSIPQYAKWLVSIFSPTAFAFALN---EAVEVHPGAQFSNLATKG----DFPVLNCIVMLIVDILLYLLIALYLDAVVPAEYGRRQPPYFIFQPSFWKTMFQRGGGSLEAHGVRRQLSAHEVYSSE-DVEPVAQEMHGREAISIHNLKKVFPG 332          
BLAST of ATP binding cassette subfamily A member 1 vs. Ensembl Medaka
Match: abca1a (ATP-binding cassette sub-family A member 1 [Source:NCBI gene;Acc:101163147])

HSP 1 Score: 257.684 bits (657), Expect = 9.810e-72
Identity = 178/552 (32.25%), Postives = 282/552 (51.09%), Query Frame = 1
Query:  772 IFDTISSWVFGKIYFSPNSPLTREIMRRANITFETLDYIRLASIEW---RLHFRDWINEAVNNSKLINELKSCKSWYFYFDNNLCET---VNAVLNF--------------QTIQSILNKISLMFSLLEKTLNCTELNKFMPI-NESITVENFIKQPM-----KSVFAVLVINDTFRYLTPSNATFLSYQIRIPENQIDSTKHFKVTDKFWTAEPRRETLRDFKYYTSGFLLLQEAIDRAFIEIVTNNETIDVGSSMQIMPYPCYVDDMFIRFITNMMPFMLVIAWVPSVTGLIKSIVYEKERRLKEFMRVMGLGNSVHWIGWFLSTVVVLIFPVTIMXXXXXXXXXXXXXXXXXXXXXXXXXXXXXICQVFMISLFFSNANLASVAGGVIYFILYMPFVVFIRMQSDLSTGFYYLGGLSAQVAFCNAINFIGYWEQSTEGAHFGNLFDGAIIDLKFGVGHCMLMLIVDSVLYLSVAWYVESVFPGQYGVGKAWYFLFTRNYWRA-KENISLAHDINNSAQLIIDYDSEGNFENEYTDLRVGISIRNLVKTY 2346
            I+  +   + GKI ++P++P T+ I+   N TF+ L  +R     W   +  F +++  +     + N L+S     F  +  L  T   V+ V NF               T +   N+       + + + C  L+K  P+ NE    E  + + M     +  +A +V  D            ++Y+IR+  + ++ T   K+ D +W   PR +   D +Y   GF  LQ+ I++  I  VT ++    G  +Q MPYPCYVDD+F+R ++  MP  + +AW+ SV  +IK +VYEKE RLKE MR+MGL N   W+ WF+S+++ L+    ++ +LL   ++L +S   VVFL L  + V  I Q F+IS  FS ANLA+  GG+IYF LY+P+V+ +  Q  +  G   L  L + VAF     +   +E+   G  + NL    + +  + +   + +++ D+VLY  + WY+ESVFPGQYG+ + WYF FT++YW   KEN       N SA L    ++E   E E   +  G+ I NLVK Y
Sbjct:  363 IWRALKPLLMGKILYTPDTPATQRIIHEVNKTFQELGVLRDLGGMWEEMKPQFWNFMENSEEMDMVRNLLQSNVGAAF-LNAQLSGTEWRVSDVANFLSKASEDKRPAGTAYTWRDAFNESDHAIQTISRFMECVNLDKLEPVANE----ERLVNKSMSLLDNQKFWAGIVFPDIVHSDNSDLPPNVNYKIRMDIDNVERTN--KIKDGYWDPGPRADPFEDLRYVWGGFSYLQDVIEQGIIRAVTGSKE-KTGIYIQQMPYPCYVDDIFLRVMSRSMPLFMTLAWMYSVAIIIKGVVYEKEARLKETMRIMGLNNGTLWLSWFISSLIPLLISAGLLVMLLKMGNLLPYSDPGVVFLFLGSFGVVTIMQCFLISTLFSRANLAAACGGIIYFTLYLPYVLCVAWQDYVGFGAKVLVSLLSPVAFGFGCEYFALFEEQGVGIQWSNLLASPLEEDSYNLTTSICLMLFDAVLYGIMTWYIESVFPGQYGIPRPWYFPFTKSYWCGEKEN------KNMSALLSKKGNAEVCIEEEPGHIEPGVYIENLVKVY 900          
BLAST of ATP binding cassette subfamily A member 1 vs. Ensembl Medaka
Match: abca1a (ATP-binding cassette sub-family A member 1 [Source:NCBI gene;Acc:101163147])

HSP 1 Score: 257.684 bits (657), Expect = 1.103e-71
Identity = 178/552 (32.25%), Postives = 282/552 (51.09%), Query Frame = 1
Query:  772 IFDTISSWVFGKIYFSPNSPLTREIMRRANITFETLDYIRLASIEW---RLHFRDWINEAVNNSKLINELKSCKSWYFYFDNNLCET---VNAVLNF--------------QTIQSILNKISLMFSLLEKTLNCTELNKFMPI-NESITVENFIKQPM-----KSVFAVLVINDTFRYLTPSNATFLSYQIRIPENQIDSTKHFKVTDKFWTAEPRRETLRDFKYYTSGFLLLQEAIDRAFIEIVTNNETIDVGSSMQIMPYPCYVDDMFIRFITNMMPFMLVIAWVPSVTGLIKSIVYEKERRLKEFMRVMGLGNSVHWIGWFLSTVVVLIFPVTIMXXXXXXXXXXXXXXXXXXXXXXXXXXXXXICQVFMISLFFSNANLASVAGGVIYFILYMPFVVFIRMQSDLSTGFYYLGGLSAQVAFCNAINFIGYWEQSTEGAHFGNLFDGAIIDLKFGVGHCMLMLIVDSVLYLSVAWYVESVFPGQYGVGKAWYFLFTRNYWRA-KENISLAHDINNSAQLIIDYDSEGNFENEYTDLRVGISIRNLVKTY 2346
            I+  +   + GKI ++P++P T+ I+   N TF+ L  +R     W   +  F +++  +     + N L+S     F  +  L  T   V+ V NF               T +   N+       + + + C  L+K  P+ NE    E  + + M     +  +A +V  D            ++Y+IR+  + ++ T   K+ D +W   PR +   D +Y   GF  LQ+ I++  I  VT ++    G  +Q MPYPCYVDD+F+R ++  MP  + +AW+ SV  +IK +VYEKE RLKE MR+MGL N   W+ WF+S+++ L+    ++ +LL   ++L +S   VVFL L  + V  I Q F+IS  FS ANLA+  GG+IYF LY+P+V+ +  Q  +  G   L  L + VAF     +   +E+   G  + NL    + +  + +   + +++ D+VLY  + WY+ESVFPGQYG+ + WYF FT++YW   KEN       N SA L    ++E   E E   +  G+ I NLVK Y
Sbjct:  376 IWRALKPLLMGKILYTPDTPATQRIIHEVNKTFQELGVLRDLGGMWEEMKPQFWNFMENSEEMDMVRNLLQSNVGAAF-LNAQLSGTEWRVSDVANFLSKASEDKRPAGTAYTWRDAFNESDHAIQTISRFMECVNLDKLEPVANE----ERLVNKSMSLLDNQKFWAGIVFPDIVHSDNSDLPPNVNYKIRMDIDNVERTN--KIKDGYWDPGPRADPFEDLRYVWGGFSYLQDVIEQGIIRAVTGSKE-KTGIYIQQMPYPCYVDDIFLRVMSRSMPLFMTLAWMYSVAIIIKGVVYEKEARLKETMRIMGLNNGTLWLSWFISSLIPLLISAGLLVMLLKMGNLLPYSDPGVVFLFLGSFGVVTIMQCFLISTLFSRANLAAACGGIIYFTLYLPYVLCVAWQDYVGFGAKVLVSLLSPVAFGFGCEYFALFEEQGVGIQWSNLLASPLEEDSYNLTTSICLMLFDAVLYGIMTWYIESVFPGQYGIPRPWYFPFTKSYWCGEKEN------KNMSALLSKKGNAEVCIEEEPGHIEPGVYIENLVKVY 913          
BLAST of ATP binding cassette subfamily A member 1 vs. Ensembl Medaka
Match: abca1a (ATP-binding cassette sub-family A member 1 [Source:NCBI gene;Acc:101163147])

HSP 1 Score: 257.299 bits (656), Expect = 1.280e-71
Identity = 178/552 (32.25%), Postives = 282/552 (51.09%), Query Frame = 1
Query:  772 IFDTISSWVFGKIYFSPNSPLTREIMRRANITFETLDYIRLASIEW---RLHFRDWINEAVNNSKLINELKSCKSWYFYFDNNLCET---VNAVLNF--------------QTIQSILNKISLMFSLLEKTLNCTELNKFMPI-NESITVENFIKQPM-----KSVFAVLVINDTFRYLTPSNATFLSYQIRIPENQIDSTKHFKVTDKFWTAEPRRETLRDFKYYTSGFLLLQEAIDRAFIEIVTNNETIDVGSSMQIMPYPCYVDDMFIRFITNMMPFMLVIAWVPSVTGLIKSIVYEKERRLKEFMRVMGLGNSVHWIGWFLSTVVVLIFPVTIMXXXXXXXXXXXXXXXXXXXXXXXXXXXXXICQVFMISLFFSNANLASVAGGVIYFILYMPFVVFIRMQSDLSTGFYYLGGLSAQVAFCNAINFIGYWEQSTEGAHFGNLFDGAIIDLKFGVGHCMLMLIVDSVLYLSVAWYVESVFPGQYGVGKAWYFLFTRNYWRA-KENISLAHDINNSAQLIIDYDSEGNFENEYTDLRVGISIRNLVKTY 2346
            I+  +   + GKI ++P++P T+ I+   N TF+ L  +R     W   +  F +++  +     + N L+S     F  +  L  T   V+ V NF               T +   N+       + + + C  L+K  P+ NE    E  + + M     +  +A +V  D            ++Y+IR+  + ++ T   K+ D +W   PR +   D +Y   GF  LQ+ I++  I  VT ++    G  +Q MPYPCYVDD+F+R ++  MP  + +AW+ SV  +IK +VYEKE RLKE MR+MGL N   W+ WF+S+++ L+    ++ +LL   ++L +S   VVFL L  + V  I Q F+IS  FS ANLA+  GG+IYF LY+P+V+ +  Q  +  G   L  L + VAF     +   +E+   G  + NL    + +  + +   + +++ D+VLY  + WY+ESVFPGQYG+ + WYF FT++YW   KEN       N SA L    ++E   E E   +  G+ I NLVK Y
Sbjct:  376 IWRALKPLLMGKILYTPDTPATQRIIHEVNKTFQELGVLRDLGGMWEEMKPQFWNFMENSEEMDMVRNLLQSNVGAAF-LNAQLSGTEWRVSDVANFLSKASEDKRPAGTAYTWRDAFNESDHAIQTISRFMECVNLDKLEPVANE----ERLVNKSMSLLDNQKFWAGIVFPDIVHSDNSDLPPNVNYKIRMDIDNVERTN--KIKDGYWDPGPRADPFEDLRYVWGGFSYLQDVIEQGIIRAVTGSKE-KTGIYIQQMPYPCYVDDIFLRVMSRSMPLFMTLAWMYSVAIIIKGVVYEKEARLKETMRIMGLNNGTLWLSWFISSLIPLLISAGLLVMLLKMGNLLPYSDPGVVFLFLGSFGVVTIMQCFLISTLFSRANLAAACGGIIYFTLYLPYVLCVAWQDYVGFGAKVLVSLLSPVAFGFGCEYFALFEEQGVGIQWSNLLASPLEEDSYNLTTSICLMLFDAVLYGIMTWYIESVFPGQYGIPRPWYFPFTKSYWCGEKEN------KNMSALLSKKGNAEVCIEEEPGHIEPGVYIENLVKVY 913          
BLAST of ATP binding cassette subfamily A member 1 vs. Ensembl Medaka
Match: ENSORLT00000025407.2 (ATP-binding cassette sub-family A member 1 [Source:NCBI gene;Acc:101163308])

HSP 1 Score: 244.202 bits (622), Expect = 3.487e-67
Identity = 186/636 (29.25%), Postives = 314/636 (49.37%), Query Frame = 1
Query:  559 TENLTASKPIIIQ-IFKVFCGSDENDFTEF----YYKFSSIST--KNVSGQTNAGSQFMNESNVTCER---NFENFFGNSNIFDTISSWVFGKIYFSPNSPLTREIMRRANITFETLDYIRLASIEWRLHFRDWINEAVNNSKLINELK----------------SCKSWYF----YFDNNLCETVNAVLNFQTIQSILNKISLMFSLLEKTLNCTELNKFMPI-NESITVENFIKQPMKSVFAVLVINDTFRYLTPSNATFL----SYQIRIPENQIDSTKHFKVTDKFWTAEPRRETLRDFKYYTSGFLLLQEAIDRAFIEIVTNNETIDVGSSMQIMPYPCYVDDMFIRFITNMMPFMLVIAWVPSVTGLIKSIVYEKERRLKEFMRVMGLGNSVHWIGWFLSTVVVLIFPVTIMXXXXXXXXXXXXXXXXXXXXXXXXXXXXXICQVFMISLFFSNANLASVAGGVIYFILYMPFVVFIRMQSDLSTGFYYLGGLSAQVAFCNAINFIGYWEQSTEGAHFGNLFDGAIIDLKFGVGHCMLMLIVDSVLYLSVAWYVESVFPGQYGVGKAWYFLFTRNYWRAKEN-----ISLAHDINNSAQLIIDYDSEGNFENEYTDLRVGISIRNLVKTY 2346
            T+N T+S   + Q + ++ CG  E    +     +Y+ S+      N +   +  + + N S   C     N ++      I+  +   + GKI ++P++P T++I+   N TF+ L   R     W    R  + + + +S+ +N ++                +   W       F +N  +  +   +  T + + N+       + + + C  L+K  P+ NE + +   +K      F   ++   F  + P NAT L    +Y+IR+  + ++ T   K+ D +W   PR +   D +Y   GF  LQ+ I++  I  +T  +    G  +Q MPYPCYVDD+F+R ++  MP  + +AW+ SV+ ++KS+VYEKE RLKE MR+MGL N + W  WF+S+++ L+    ++ LLL   ++L +S   V+FL L  + V  I Q F+IS  F+ ANLA+  GG+IYF LY+P+V+ +  Q  +  G   +  L + VAF     +   +E+   G  + NL    + +  F +   +L++  DS LY  + WY+E+VFPGQYG+ + WYF FT++YW   ++     I L    N +A  +         E E   L  G+ I NLVK Y
Sbjct:  297 TQNATSSPSAMYQAVSRIVCGHPEGGGLQIKSLNWYEDSNYKALFGNHNSSEDESTLYDNSSTPFCNSLVSNMDSSPMAHMIWQALKPLLLGKILYTPHTPATQKIIHEVNRTFQELGVFRDLGGMWE-EMRPKVWDFMESSQEMNMIRTMLKNNITASFLTSKLASTDWTVDTLSTFLSNQVDNSHLPESIVTWRKVFNETDQAIMSISRFMECVNLDKLEPVSNEELMINRSMKLLEDRKFWAGIV---FPDIAP-NATALPPKVNYKIRMDIDNVERTN--KIKDAYWDPGPRADPFEDMRYIWGGFTYLQDVIEQGIIRALTGTKE-KTGVYIQQMPYPCYVDDIFLRVMSRSMPLFMTLAWMYSVSIILKSVVYEKEARLKETMRIMGLDNGILWFSWFISSLIPLLISAGLLVLLLKKGNLLPYSDPGVIFLFLGSFAVVTIMQCFLISTAFARANLAAACGGIIYFTLYLPYVLCVAWQDYIGYGAKVMASLLSPVAFGFGCEYFALFEEQGVGIQWSNLLSSPLQEDDFSLRTTILVMYFDSFLYGVLTWYIEAVFPGQYGIPRPWYFPFTKSYWFGDKDENSSKIPLNRRRNQTAVCV---------EEEPAHLEPGVYIENLVKVY 915          
BLAST of ATP binding cassette subfamily A member 1 vs. Ensembl Medaka
Match: abca4a (retinal-specific ATP-binding cassette transporter [Source:NCBI gene;Acc:101171449])

HSP 1 Score: 232.261 bits (591), Expect = 2.652e-63
Identity = 167/589 (28.35%), Postives = 298/589 (50.59%), Query Frame = 1
Query:  685 GQTNAGSQFMNESNVT--CE---RNFENFFGNSNIFDTISSWVFGKIYFSPNSPLTREIMRRANITFETLDYIRLASIEWR-------LHFRDWINEAVNNSKLINELKSCKSWYFYFDNNLCE---TVNAVLNFQTIQSILNK---------------ISLMFSLLEKTLNCTELNKF--MPINESITVENFIKQPMKSVFAVLVINDTFRYLTPSNATFLSYQIRIPENQIDSTKHFKVTDKFWTAEPRRETLRDFKYYTSGFLLLQEAIDRAFIEIVTNNETIDVGSSMQIMPYPCYVDDMFIRFITNMMPFMLVIAWVPSVTGLIKSIVYEKERRLKEFMRVMGLGNSVHWIGWFLSTVVVLIFPVTIMXXXXXXXXXXXXXXXXXXXXXXXXXXXXXICQVFMISLFFSNANLASVAGGVIYFILYMPFVVFIRMQSDLSTGFYYLGGLSAQVAFCNAINFIGYWEQSTEGAHFGNLFDGAIIDLKFGVGHCMLMLIVDSVLYLSVAWYVESVFPGQYGVGKAWYFLFTRNYWRAKENISLAHDINNSAQLIIDYDSEGN---FENEYTDLRVGISIRNLVKTY 2346
            G++ A   +  +++ T  C    R  E+      +++++   + G+I ++P+SP  R +++ AN TFE L+ +R     W          F+D I       ++I ++    S   + D +L +   +   +LNF   + + ++               I  +  +L +  +C  L+KF  +P  +++T            +A L+  +   + T S    + ++IR+  + ++ T   KV D++W   PR + + D +Y   GF   Q+ I+   I   T  E   +G  +Q MPYPCYVDD+F   +    P  +V+AWV SV+ ++KSIV EKE RLKE ++ MG+ N V W  WF+ + +++     +++ +++   +L++S   ++FL LL +  + I Q F++S+FF+ A LA+   G+IYF LY+P V  I  Q  ++     L  L +QVAF     ++  +E+   G  + N+    +   +F     + M+++D+VLY  +AWY+++VFPGQYG+G+ +YF     YW  K+N           + I++  SE +   FE E  +L  G+ I NLVK +
Sbjct:  350 GRSRAKDDYTYDNSTTPFCNDLMRELESNPATRVMWNSVKPMLMGRILYAPDSPAVRRVIKNANTTFEELERLRTMGKAWEEVAPQIWAFFQDGI-----QVEMIRDIIRNPSVMDFIDKSLEDAPFSSKHILNFLRNEPLEDRPYDVPNFDWRDVFKMIDRVIRMLNQYGDCVVLDKFVALPDEDAVTYRALNLLEDGKFWAGLIFVNMHPWTT-SVPPHIKFKIRMDIDIVERTN--KVKDRYWDPGPRADPMEDLRYVWGGFAYFQDIIEHGIIRTHTGKE-WPLGVYLQQMPYPCYVDDLFTLTLNRCFPVFMVLAWVYSVSMVVKSIVLEKELRLKETLKTMGVTNGVIWSTWFIDSFIMMGTSTALLTAIIMGGRVLNYSNPFILFLFLLTFTTATIMQCFLLSVFFNQAKLAAACCGIIYFTLYLPHVFCIAWQDRITKDMKILLSLLSQVAFGFGTEYLSRYEEQGMGLQWDNIQTSPLEGDEFSFLTSICMMVLDTVLYSVLAWYLDNVFPGQYGIGRPFYFPLLPCYWLNKKNRK-----KRILKKILEKVSEQDMSFFEAEPDNLVKGVCIENLVKVF 924          
BLAST of ATP binding cassette subfamily A member 1 vs. Planmine SMEST
Match: SMESG000029534.1 (SMESG000029534.1)

HSP 1 Score: 1442.94 bits (3734), Expect = 0.000e+0
Identity = 750/760 (98.68%), Postives = 755/760 (99.34%), Query Frame = 1
Query:   76 MNSIFTKQLKVLLWKNFRLKKRKPITLISEXXXXXXXXXXXXXXRNSIFKFKMDHCEFKEKSMASMGFVPFILDFFCTFNTTCYNKTQINWNENYSSIYAFKMFTKNLYNVYQTLPKEKLTVNSLITWATNHKFEIDQLISNIMPIIKLLSPLIASLKEADTENLTASKPIIIQIFKVFCGSDENDFTEFYYKFSSISTKNVSGQTNAGSQFMNESNVTCERNFENFFGNSNIFDTISSWVFGKIYFSPNSPLTREIMRRANITFETLDYIRLASIEWRLHFRDWINEAVNNSKLINELKSCKSWYFYFDNNLCETVNAVLNFQTIQSILNKISLMFSLLEKTLNCTELNKFMPINESITVENFIKQPMKSVFAVLVINDTFRYLTPSNATFLSYQIRIPENQIDSTKHFKVTDKFWTAEPRRETLRDFKYYTSGFLLLQEAIDRAFIEIVTNNETIDVGSSMQIMPYPCYVDDMFIRFITNMMPFMLVIAWVPSVTGLIKSIVYEKERRLKEFMRVMGLGNSVHWIGWFLSTVVVLIFPVTIMXXXXXXXXXXXXXXXXXXXXXXXXXXXXXICQVFMISLFFSNANLASVAGGVIYFILYMPFVVFIRMQSDLSTGFYYLGGLSAQVAFCNAINFIGYWEQSTEGAHFGNLFDGAIIDLKFGVGHCMLMLIVDSVLYLSVAWYVESVFPGQYGVGKAWYFLFTRNYWRAKENISLAHDINNSAQLIIDYDSEGNFENEYTDLRVGISIRNLVKTYPGA 2355
            MNSIFTKQLKVLLWKNFRLKKRKPITLISEILVPLLIIIIIVPVRNSIFKFKMDHCEFKEKSMASMGFVPFILDFFCTFNTTCYNKTQINWNENYSSIYAFKMFTKNLYNVYQTLPKEKLTVNSLITWAT HKFEIDQLISNIMPIIKLLSPLIASLKEADTENLTASKPIIIQIFKVFCGSDENDFTEFYYKFSSISTKNVSGQTNAGSQFMNESNVTCERNFENFFGNSNIF TISSWVFGKIYFSPNSPLTREIMRRANITFETLDYIRLASIEWRLHFRDWINEAVNNSKLINELKSCKSWYFYFDNNLCETVNAVLNFQTIQSILNKISLMFS LEKTLNCTELNKF+PINESITVENFIKQP+KSVFAVLVINDTFRYLTPSNATFL+YQIRIPE+QIDSTKHFKVTDKFWTAEPRRETLRDFKYYTSGFLLLQEAIDRAFIEIVTNNETIDVGSSMQIMPYPCYVDDMFIRFITNMMPFMLVIAWVPSVTGLIKSIVYEKERRLKEFMRVMGLGNSVHWIGWFLSTVVVLIFPVTIMSLLLIYSSILSFSCFAVVFLVLLLYVVSFICQVFMISLFF+NANLASVAGGVIYFILYMPFVVFIRMQSDLSTGFYYLGGLSAQVAFCNAINFIGYWEQSTEGAHFGNLFDGAIIDLKFGVGHCMLMLIVDSVLYLSVAWYVESVFPGQYGVGKAWYFLFTRNYWRAKENISLAHDINNS  LIIDYDSEGNFENEYTDLRVGISIRNLVKTYPGA
Sbjct:    1 MNSIFTKQLKVLLWKNFRLKKRKPITLISEILVPLLIIIIIVPVRNSIFKFKMDHCEFKEKSMASMGFVPFILDFFCTFNTTCYNKTQINWNENYSSIYAFKMFTKNLYNVYQTLPKEKLTVNSLITWATIHKFEIDQLISNIMPIIKLLSPLIASLKEADTENLTASKPIIIQIFKVFCGSDENDFTEFYYKFSSISTKNVSGQTNAGSQFMNESNVTCERNFENFFGNSNIFGTISSWVFGKIYFSPNSPLTREIMRRANITFETLDYIRLASIEWRLHFRDWINEAVNNSKLINELKSCKSWYFYFDNNLCETVNAVLNFQTIQSILNKISLMFSFLEKTLNCTELNKFVPINESITVENFIKQPIKSVFAVLVINDTFRYLTPSNATFLNYQIRIPESQIDSTKHFKVTDKFWTAEPRRETLRDFKYYTSGFLLLQEAIDRAFIEIVTNNETIDVGSSMQIMPYPCYVDDMFIRFITNMMPFMLVIAWVPSVTGLIKSIVYEKERRLKEFMRVMGLGNSVHWIGWFLSTVVVLIFPVTIMSLLLIYSSILSFSCFAVVFLVLLLYVVSFICQVFMISLFFNNANLASVAGGVIYFILYMPFVVFIRMQSDLSTGFYYLGGLSAQVAFCNAINFIGYWEQSTEGAHFGNLFDGAIIDLKFGVGHCMLMLIVDSVLYLSVAWYVESVFPGQYGVGKAWYFLFTRNYWRAKENISLAHDINNSEPLIIDYDSEGNFENEYTDLRVGISIRNLVKTYPGA 760          
BLAST of ATP binding cassette subfamily A member 1 vs. Planmine SMEST
Match: SMESG000056983.1 (SMESG000056983.1)

HSP 1 Score: 679.478 bits (1752), Expect = 0.000e+0
Identity = 361/768 (47.01%), Postives = 517/768 (67.32%), Query Frame = 1
Query:   97 QLKVLLWKNFRLKKRKPITLISEXXXXXXXXXXXXXXRNSIFKFKMDHCEFKEKSMASMGFVPFILDFFCTFNTTCYNKTQINWNENYSSIYAFKMFTKNLYNVYQTLPKEKLTVNSLITWATNHKFEIDQLISNIMPIIKLLSPLIASLKEADTENLTASKPIIIQIFKVFCGSDENDFTEFYYKFSSISTKNVSGQTNAGSQFMNESNVTCERNFENFFG----NSNIFDTISSWVFGKIYFSPNSPLTREIMRRANITFETLDYIRLASIEWRLHFRDWINEAVNNSKLI----NELKSC--KSWYFYFDNNLCETVNAVLNFQTIQSILNKISLMFSLLEKTLNCTELNKFMPINESITVENFIKQPMKSVFAVLVINDTFRYLTPSNATFLSYQIRIPENQIDSTKHFKVTDKFWTAEPRRETLRDFKYYTSGFLLLQEAIDRAFIEIVTNNETIDVGSSMQIMPYPCYVDDMFIRFITNMMPFMLVIAWVPSVTGLIKSIVYEKERRLKEFMRVMGLGNSVHWIGWFLSTVVVLIFPVTIMXXXXXXXXXXXXXXXXXXXXXXXXXXXXXICQVFMISLFFSNANLASVAGGVIYFILYMPFVVFIRMQSDLSTGFYYLGGLSAQVAFCNAINFIGYWEQSTEGAHFGNLFDGAIIDLKFGVGHCMLMLIVDSVLYLSVAWYVESVFPGQYGVGKAWYFLFTRNYW----RAKENISLAHDINNSAQ-LIIDYDSEGNFENEYTDLRVGISIRNLVKTYPGA 2355
            Q+ +LLWKNFRL+KR+P  L  EIL+ L  I+ ++ +R +  KF++  CE +EK+MAS+G +PF+ D+ CTFNTTCYN+TQI+W +N ++ Y    F  N   +Y + PK +LT    + W   H  E + L  +++ +   +  ++ S+   ++ N       I ++  + CGSD+ND     +  + +     S QT             C+  +E +      +  +    +  +FGKIYF+P+S  TR+I+++ANITFE LD +RL+++EWRL+FRDW++  VNNS  +    N  K C   S  +Y    +C+ +    +   IQ+ +   S +F L+E+ LNCTELNKF P+   + ++N  +  + ++FA +V N++F+YLT +NAT L+YQIR+P N+IDSTK+FKV D FW   PRR+T+ D KYYTSGFL LQEA D+AFIE+VT N TI++G+SMQIMPYPC+VDD FI+F++ +MPF+L+IAW PSVT +IKSIVYEKE RLKEFM +MGL N VHW  WF+ST+VVLIFPV  M+L+L Y+ I+ FS   ++F+++L YV+SFICQ FMIS+FF N+N+A++ GG++YFI Y+PF+VFI  Q +LST  YY  GL  QV+FCNAINFIGY EQ+++GA F NLF+  IIDL FGVGHC++M+ +DS+ Y+ +AWYVE+VFPG+YGV K WYFLFTR+YW    +  +NI ++ +     + + ID      FE E  DL +GI I NLVK +P +
Sbjct:    9 QISLLLWKNFRLRKRRPFQLTFEILICLSFILSLIGIRQAQLKFRIGRCELREKNMASLGPIPFLRDYLCTFNTTCYNETQIDWKDNKTNDYL--TFLNNCTRIYNSYPKRQLTSTEFLQWLILHPEESEMLRYSLIFLNAKIDYVVESIDLINSGNSNNVSRGINKLTTMICGSDKNDAAILIFNLNLLQRSKRSIQT-------------CQEVYEKYLSVDYFHRQLLGMTAPIIFGKIYFTPDSEFTRQIIKKANITFEILDNLRLSAVEWRLNFRDWLSNQVNNSSTLDNMSNNAKVCMETSQNYY---TVCQLIYKSSDRNRIQNSIEIASRIFDLIERGLNCTELNKFQPMKSKVDIDNLAQNKLINIFAGVVFNESFQYLTLNNATVLNYQIRMPTNRIDSTKNFKVLDTFWNPIPRRDTIYDLKYYTSGFLFLQEAFDQAFIELVTGNVTINIGTSMQIMPYPCFVDDRFIKFLSMIMPFILIIAWTPSVTIIIKSIVYEKENRLKEFMLLMGLTNFVHWCSWFISTIVVLIFPVIFMTLILKYNEIIQFSSPGIIFILILSYVISFICQSFMISVFFDNSNVAAIVGGIVYFIFYLPFLVFINFQDELSTEMYYGVGLLTQVSFCNAINFIGYLEQASDGAQFSNLFNSTIIDLNFGVGHCLIMIWIDSIFYILIAWYVEAVFPGKYGVPKPWYFLFTRHYWIPFSKNNDNIEISDNFRQREENIAID-----GFEKEPDDLEIGILIENLVKKFPKS 753          
BLAST of ATP binding cassette subfamily A member 1 vs. Planmine SMEST
Match: SMESG000032896.1 (SMESG000032896.1)

HSP 1 Score: 677.167 bits (1746), Expect = 0.000e+0
Identity = 370/710 (52.11%), Postives = 495/710 (69.72%), Query Frame = 1
Query:  262 MASMGFVPFILDFFCTFNTTCYNKTQINWNENYSSIYAFKMFTKNLYNVYQTLPKEKLTVNSLITWATNHKFEIDQLISNIMPIIKLLSPLIASLKEADTENLTASKPIIIQIFKVFCGSDENDFTEFYYKFSSISTKNVSGQTNAGSQFMNESNVTCERNFENFFGNSN----IFDTISSWVFGKIYFSPNSPLTREIMRRANITFETLDYIRLASIEWRLHFRDWINEAVNNSKLINELKSCKSWYFYFDNNLCETVNAVLNFQTIQSILNKISLMFSLLEKTLNCTELNKFMPINESITVENFIKQPMKSVFAVLVINDTFRYLTPSNATFLSYQIRIPENQIDSTKHFKVTDKFWTAEPRRETLRDFKYYTSGFLLLQEAIDRAFIEIV-TNNETIDVGSSMQIMPYPCYVDDMFIRFITNMMPFMLVIAWVPSVTGLIKSIVYEKERRLKEFMRVMGLGNSVHWIGWFLSTVVVLIFPVTIMXXXXXXXXXXXXXXXXXXXXXXXXXXXXXICQVFMISLFFSNANLASVAGGVIYFILYMPFVVFIRMQSDLSTGFYYLGGLSAQVAFCNAINFIGYWEQSTEGAHFGNLFDGAIIDLKFGVGHCMLMLIVDSVLYLSVAWYVESVFPGQYGVGKAWYFLFTRNYW---RAKENISLAHDINNSAQLIIDYDSEG----NFENEYTDLRVGISIRNLVKTYPGA 2355
            MASMG +PF+ DF CT NTTCYNKTQI+W+ N ++   F+ F  N+  +Y  L K          + T    +I QL  ++  +     PL+ ++ +  + N T S   +  I    CGS END   F   F           TN  S+    S  +C+  F    G+S+    ++  ++  +FGKIY++P+SP TRE+++RAN TF+ LD +RL+++EWRLHF  +    +NNS+ IN L++           +C TVNA+L+ + I +    IS +F+++E +LNCTELNKF+P+  SI ++N   Q + +++A LVIN++F+YLT +NATFLSYQIR+P N+ID+T  FKV D +WT  PR  TL DFKYYTSGF+LLQEA+D+AFIEIV TNNE+I+VGSSMQIMPYPCYV+D FI+F+++MMPF+L+IAW+PSVT L+K IVYEKE RLKEFM+VMGL N VHWIGWF++T+ +L+ P+ IM+L+L YS+IL FS  AVVFL+LL YVVSFICQ FMIS+FF  AN+A+VAGG+IY ILY+PF VFI +  D++   YY  GL  QVAFCN+INFI +WEQST+G  F NLFD  +++L  GVGHCM+M+ VDSV+YL +AWYVESVFPGQYGVGK WYFLFTR+YW    A + I+L  +  +   L I   +EG     FE+E T+L+VGISI+NLVKTYPGA
Sbjct:    1 MASMGPIPFLRDFLCTLNTTCYNKTQIDWSGNNTN--DFQTFLNNMTYLYGVLNKP---------FPTPTPNDITQLTYSLNYLNSSTYPLLVAMMQIQSGNKTESDKGMKTIEASICGSSENDMNLFVNSFV----------TNQKSK---RSLQSCQNQFLQTLGSSSYGSQMYQVLAPLIFGKIYYTPDSPFTRELIKRANSTFKILDDLRLSAVEWRLHFSSYFVNYMNNSQPINNLRNFCKLNIPGTQQMCSTVNAILDMENILAYNAAISAVFAIIENSLNCTELNKFVPMKSSIDIDNLANQSLTNIYAGLVINESFQYLTRNNATFLSYQIRMPTNRIDTTLKFKVLDSYWTPAPRINTLTDFKYYTSGFMLLQEALDQAFIEIVSTNNESINVGSSMQIMPYPCYVNDKFIKFLSSMMPFLLIIAWMPSVTNLLKGIVYEKENRLKEFMQVMGLSNLVHWIGWFITTISILMLPIIIMTLILHYSTILDFSSPAVVFLILLSYVVSFICQSFMISVFFDKANVAAVAGGIIYSILYLPFYVFITIPDDVTDSMYYGVGLLTQVAFCNSINFIAFWEQSTDGVQFSNLFDSTVVNLNVGVGHCMVMMWVDSVIYLLIAWYVESVFPGQYGVGKPWYFLFTRHYWCQNSASDKITLIDNHYSYESLPIPNINEGILKHGFESEPTNLKVGISIKNLVKTYPGA 686          
BLAST of ATP binding cassette subfamily A member 1 vs. Planmine SMEST
Match: SMESG000032861.1 (SMESG000032861.1)

HSP 1 Score: 676.396 bits (1744), Expect = 0.000e+0
Identity = 371/720 (51.53%), Postives = 494/720 (68.61%), Query Frame = 1
Query:  232 MDHCEFKEKSMASMGFVPFILDFFCTFNTTCYNKTQINWNENYSSIYAFKMFTKNLYNVYQTLPKEKLTVNSLITWATNHKFEIDQLISNIMPIIKLLSPLIASLKEADTENLTASKPIIIQIFKVFCGSDENDFTEFYYKFSSISTKNVSGQTNAGSQFMNESNVTCERNFENFFGNSN----IFDTISSWVFGKIYFSPNSPLTREIMRRANITFETLDYIRLASIEWRLHFRDWINEAVNNSKLINELKSCKSWYFYFDNNLCETVNAVLNFQTIQSILNKISLMFSLLEKTLNCTELNKFMPINESITVENFIKQPMKSVFAVLVINDTFRYLTPSNATFLSYQIRIPENQIDSTKHFKVTDKFWTAEPRRETLRDFKYYTSGFLLLQEAIDRAFIEIV-TNNETIDVGSSMQIMPYPCYVDDMFIRFITNMMPFMLVIAWVPSVTGLIKSIVYEKERRLKEFMRVMGLGNSVHWIGWFLSTVVVLIFPVTIMXXXXXXXXXXXXXXXXXXXXXXXXXXXXXICQVFMISLFFSNANLASVAGGVIYFILYMPFVVFIRMQSDLSTGFYYLGGLSAQVAFCNAINFIGYWEQSTEGAHFGNLFDGAIIDLKFGVGHCMLMLIVDSVLYLSVAWYVESVFPGQYGVGKAWYFLFTRNYW---RAKENISLAHDINNSAQLIIDYDSEG----NFENEYTDLRVGISIRNLVKTYPGA 2355
            MD CE +EK MASMG +PF+ DF CT NTTCYNKTQI+W+ N ++   F+ F  N+  +Y    K          + T    +I QL  ++  +     PL+ ++ +  + N T S   +  I    CGS END   F   F           TN  S+    S  +C+  F    G+S+    +++ I+  +FGKIY++P+SP TRE+++RAN TF+ LD +RL+++EWRLHF  +    +NNS+ IN L++           +C TVN  L+ + I +    IS +F+++E +LNCTELNKF+P+  SI ++N   Q + +++A LVIN++F+YLT +NATFLSYQIR+P N+ID+T  FKV D FWT  PR  T  DFKYYTSGF+LLQEA+D+AFIEIV TNNE+I+VGSSMQIMPYPCYV+D FI+F+++MMPF+L+IAW+PSVT L+K IVYEKE RLKEFM+VMGL N VHWIGWF++T+ +L+ P+ IM+L+L YS+IL FS  AVVFL+LL YVVSFICQ FMIS+FF  AN+A+VAGG+IYFI Y+PF VFI +  D++   YY  GL  QVAF N+INFI +WEQST+G  F NLFD  +++L  GVGHCM+M+ VDSV+YL +AWYVESVFPGQYGVGK WYFLFT++YW    A   I+   +        I   +EG     FE+E T+L+VGISI+NLVKTYPGA
Sbjct:    1 MDLCELREKQMASMGPIPFLRDFLCTLNTTCYNKTQIDWSGNNTN--DFQTFLNNMTYLYDVFNKP---------FPTPTPNDITQLTYSLNYLNSSTYPLLVAMMQIQSGNKTESDKGMKTIEASICGSSENDMNLFVNSFV----------TNQKSK---RSLQSCQNQFLQTLGSSSYGSQLYEVIAPLIFGKIYYTPDSPFTRELIKRANSTFKILDDLRLSAVEWRLHFSSYFVNYMNNSQPINNLRNFCKLNIPGTQQMCSTVNTTLDMENILAYNAAISAVFAIIENSLNCTELNKFVPMKSSIDIDNLANQSLTNIYAGLVINESFQYLTRNNATFLSYQIRMPTNRIDTTLKFKVIDSFWTPAPRISTFSDFKYYTSGFMLLQEALDQAFIEIVSTNNESINVGSSMQIMPYPCYVNDKFIKFLSSMMPFLLIIAWMPSVTILLKGIVYEKENRLKEFMQVMGLSNLVHWIGWFITTISILMLPIIIMTLILRYSTILGFSSPAVVFLILLSYVVSFICQSFMISVFFDKANVAAVAGGIIYFISYLPFYVFITIPDDVTDSMYYGVGLLTQVAFSNSINFIAFWEQSTDGVQFSNLFDSTVVNLNVGVGHCMVMMWVDSVIYLLIAWYVESVFPGQYGVGKPWYFLFTQHYWCQNSASYKITPIDNYYPYESSPIPNINEGILKHGFESEPTNLKVGISIKNLVKTYPGA 696          
BLAST of ATP binding cassette subfamily A member 1 vs. Planmine SMEST
Match: SMESG000032896.1 (SMESG000032896.1)

HSP 1 Score: 671.774 bits (1732), Expect = 0.000e+0
Identity = 367/707 (51.91%), Postives = 492/707 (69.59%), Query Frame = 1
Query:  271 MGFVPFILDFFCTFNTTCYNKTQINWNENYSSIYAFKMFTKNLYNVYQTLPKEKLTVNSLITWATNHKFEIDQLISNIMPIIKLLSPLIASLKEADTENLTASKPIIIQIFKVFCGSDENDFTEFYYKFSSISTKNVSGQTNAGSQFMNESNVTCERNFENFFGNSN----IFDTISSWVFGKIYFSPNSPLTREIMRRANITFETLDYIRLASIEWRLHFRDWINEAVNNSKLINELKSCKSWYFYFDNNLCETVNAVLNFQTIQSILNKISLMFSLLEKTLNCTELNKFMPINESITVENFIKQPMKSVFAVLVINDTFRYLTPSNATFLSYQIRIPENQIDSTKHFKVTDKFWTAEPRRETLRDFKYYTSGFLLLQEAIDRAFIEIV-TNNETIDVGSSMQIMPYPCYVDDMFIRFITNMMPFMLVIAWVPSVTGLIKSIVYEKERRLKEFMRVMGLGNSVHWIGWFLSTVVVLIFPVTIMXXXXXXXXXXXXXXXXXXXXXXXXXXXXXICQVFMISLFFSNANLASVAGGVIYFILYMPFVVFIRMQSDLSTGFYYLGGLSAQVAFCNAINFIGYWEQSTEGAHFGNLFDGAIIDLKFGVGHCMLMLIVDSVLYLSVAWYVESVFPGQYGVGKAWYFLFTRNYW---RAKENISLAHDINNSAQLIIDYDSEG----NFENEYTDLRVGISIRNLVKTYPGA 2355
            MG +PF+ DF CT NTTCYNKTQI+W+ N ++   F+ F  N+  +Y  L K          + T    +I QL  ++  +     PL+ ++ +  + N T S   +  I    CGS END   F   F           TN  S+    S  +C+  F    G+S+    ++  ++  +FGKIY++P+SP TRE+++RAN TF+ LD +RL+++EWRLHF  +    +NNS+ IN L++           +C TVNA+L+ + I +    IS +F+++E +LNCTELNKF+P+  SI ++N   Q + +++A LVIN++F+YLT +NATFLSYQIR+P N+ID+T  FKV D +WT  PR  TL DFKYYTSGF+LLQEA+D+AFIEIV TNNE+I+VGSSMQIMPYPCYV+D FI+F+++MMPF+L+IAW+PSVT L+K IVYEKE RLKEFM+VMGL N VHWIGWF++T+ +L+ P+ IM+L+L YS+IL FS  AVVFL+LL YVVSFICQ FMIS+FF  AN+A+VAGG+IY ILY+PF VFI +  D++   YY  GL  QVAFCN+INFI +WEQST+G  F NLFD  +++L  GVGHCM+M+ VDSV+YL +AWYVESVFPGQYGVGK WYFLFTR+YW    A + I+L  +  +   L I   +EG     FE+E T+L+VGISI+NLVKTYPGA
Sbjct:    1 MGPIPFLRDFLCTLNTTCYNKTQIDWSGNNTN--DFQTFLNNMTYLYGVLNKP---------FPTPTPNDITQLTYSLNYLNSSTYPLLVAMMQIQSGNKTESDKGMKTIEASICGSSENDMNLFVNSFV----------TNQKSK---RSLQSCQNQFLQTLGSSSYGSQMYQVLAPLIFGKIYYTPDSPFTRELIKRANSTFKILDDLRLSAVEWRLHFSSYFVNYMNNSQPINNLRNFCKLNIPGTQQMCSTVNAILDMENILAYNAAISAVFAIIENSLNCTELNKFVPMKSSIDIDNLANQSLTNIYAGLVINESFQYLTRNNATFLSYQIRMPTNRIDTTLKFKVLDSYWTPAPRINTLTDFKYYTSGFMLLQEALDQAFIEIVSTNNESINVGSSMQIMPYPCYVNDKFIKFLSSMMPFLLIIAWMPSVTNLLKGIVYEKENRLKEFMQVMGLSNLVHWIGWFITTISILMLPIIIMTLILHYSTILDFSSPAVVFLILLSYVVSFICQSFMISVFFDKANVAAVAGGIIYSILYLPFYVFITIPDDVTDSMYYGVGLLTQVAFCNSINFIAFWEQSTDGVQFSNLFDSTVVNLNVGVGHCMVMMWVDSVIYLLIAWYVESVFPGQYGVGKPWYFLFTRHYWCQNSASDKITLIDNHYSYESLPIPNINEGILKHGFESEPTNLKVGISIKNLVKTYPGA 683          
The following BLAST results are available for this feature:
BLAST of ATP binding cassette subfamily A member 1 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5
Match NameE-valueIdentityDescription
ABCA15.060e-7731.73ATP binding cassette subfamily A member 1 [Source:... [more]
ABCA78.943e-6430.00ATP binding cassette subfamily A member 7 [Source:... [more]
ABCA47.843e-5929.06ATP binding cassette subfamily A member 4 [Source:... [more]
ABCA124.916e-5026.16ATP binding cassette subfamily A member 12 [Source... [more]
ABCA124.971e-5026.16ATP binding cassette subfamily A member 12 [Source... [more]
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BLAST of ATP binding cassette subfamily A member 1 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 3
Match NameE-valueIdentityDescription
abt-23.394e-4428.44ABC Transporter family [Source:UniProtKB/TrEMBL;A... [more]
abt-24.121e-4428.44ABC Transporter family [Source:UniProtKB/TrEMBL;A... [more]
abt-43.143e-3029.34ABC Transporter family [Source:UniProtKB/TrEMBL;A... [more]
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BLAST of ATP binding cassette subfamily A member 1 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5
Match NameE-valueIdentityDescription
ABCA5.953e-3829.19gene:FBgn0031170 transcript:FBtr0332489[more]
ABCA7.012e-3829.19gene:FBgn0031170 transcript:FBtr0332488[more]
ABCA7.023e-3829.19gene:FBgn0031170 transcript:FBtr0306679[more]
CG60521.147e-3026.95gene:FBgn0036747 transcript:FBtr0075195[more]
CG312132.278e-2127.27gene:FBgn0051213 transcript:FBtr0335242[more]
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BLAST of ATP binding cassette subfamily A member 1 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
abca1b1.108e-7029.72ATP-binding cassette, sub-family A (ABC1), member ... [more]
abca1b1.294e-7029.72ATP-binding cassette, sub-family A (ABC1), member ... [more]
abca1a1.406e-7030.24ATP-binding cassette, sub-family A (ABC1), member ... [more]
abca1a1.406e-7030.24ATP-binding cassette, sub-family A (ABC1), member ... [more]
zgc:1723024.930e-7029.15zgc:172302 [Source:ZFIN;Acc:ZDB-GENE-081205-5][more]
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BLAST of ATP binding cassette subfamily A member 1 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5
Match NameE-valueIdentityDescription
ABCA13.759e-7430.47ATP binding cassette subfamily A member 1 [Source:... [more]
ABCA15.983e-7430.25ATP binding cassette subfamily A member 1 [Source:... [more]
ABCA18.679e-7430.25ATP binding cassette subfamily A member 1 [Source:... [more]
ABCA18.767e-7430.25ATP binding cassette subfamily A member 1 [Source:... [more]
ABCA18.790e-7430.25ATP binding cassette subfamily A member 1 [Source:... [more]
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BLAST of ATP binding cassette subfamily A member 1 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Abca11.557e-7631.91ATP-binding cassette, sub-family A (ABC1), member ... [more]
Abca72.066e-6029.56ATP-binding cassette, sub-family A (ABC1), member ... [more]
Abca72.281e-6029.35ATP-binding cassette, sub-family A (ABC1), member ... [more]
Abca72.281e-6029.35ATP-binding cassette, sub-family A (ABC1), member ... [more]
Abca43.449e-6030.20ATP-binding cassette, sub-family A (ABC1), member ... [more]
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BLAST of ATP binding cassette subfamily A member 1 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|O95477|ABCA1_HUMAN2.430e-7631.73Phospholipid-transporting ATPase ABCA1 OS=Homo sap... [more]
sp|P41233|ABCA1_MOUSE1.089e-7531.91Phospholipid-transporting ATPase ABCA1 OS=Mus musc... [more]
sp|Q8IZY2|ABCA7_HUMAN4.294e-6330.00Phospholipid-transporting ATPase ABCA7 OS=Homo sap... [more]
sp|Q7TNJ2|ABCA7_RAT2.844e-6229.63ATP-binding cassette sub-family A member 7 OS=Ratt... [more]
sp|O35600|ABCA4_MOUSE2.413e-5930.20Retinal-specific phospholipid-transporting ATPase ... [more]
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BLAST of ATP binding cassette subfamily A member 1 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
A0A4X2KQE61.270e-8028.14ATP binding cassette subfamily A member 7 OS=Vomba... [more]
A0A3Q3RRK18.451e-7929.53Zgc:172302 OS=Mastacembelus armatus OX=205130 PE=4... [more]
A0A4W3K1G78.589e-7927.83Uncharacterized protein OS=Callorhinchus milii OX=... [more]
W5LAQ71.203e-7828.78ATP binding cassette subfamily A member 1 OS=Astya... [more]
A0A3Q3L2S54.606e-7828.78Zgc:172302 OS=Mastacembelus armatus OX=205130 PE=4... [more]
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BLAST of ATP binding cassette subfamily A member 1 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
ENSAMXT00000016919.24.557e-8228.78pep primary_assembly:Astyanax_mexicanus-2.0:8:9912... [more]
abca1a8.302e-7129.09ATP-binding cassette sub-family A member 1-like [S... [more]
abca1a8.302e-7129.09ATP-binding cassette sub-family A member 1-like [S... [more]
abca1a9.367e-7129.09ATP-binding cassette sub-family A member 1-like [S... [more]
abca4a2.442e-6927.77retinal-specific ATP-binding cassette transporter-... [more]
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BLAST of ATP binding cassette subfamily A member 1 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 5
Match NameE-valueIdentityDescription
ENSPMAT00000002495.11.001e-6033.96pep scaffold:Pmarinus_7.0:GL480265:53:27909:1 gene... [more]
ENSPMAT00000004117.18.252e-4432.15pep scaffold:Pmarinus_7.0:GL489716:190:6182:-1 gen... [more]
abca127.150e-3226.80ATP-binding cassette, sub-family A (ABC1), member ... [more]
ENSPMAT00000001954.17.744e-1735.29pep scaffold:Pmarinus_7.0:GL484253:245:9303:-1 gen... [more]
ENSPMAT00000001952.11.967e-1635.29pep scaffold:Pmarinus_7.0:GL484253:245:9555:-1 gen... [more]
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BLAST of ATP binding cassette subfamily A member 1 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of ATP binding cassette subfamily A member 1 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 4
Match NameE-valueIdentityDescription
EDO468781.308e-6134.86Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO388792.793e-5227.93Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO489513.467e-3830.72Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO320703.332e-2130.68Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
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BLAST of ATP binding cassette subfamily A member 1 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5
Match NameE-valueIdentityDescription
abca1a9.810e-7232.25ATP-binding cassette sub-family A member 1 [Source... [more]
abca1a1.103e-7132.25ATP-binding cassette sub-family A member 1 [Source... [more]
abca1a1.280e-7132.25ATP-binding cassette sub-family A member 1 [Source... [more]
ENSORLT00000025407.23.487e-6729.25ATP-binding cassette sub-family A member 1 [Source... [more]
abca4a2.652e-6328.35retinal-specific ATP-binding cassette transporter ... [more]
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BLAST of ATP binding cassette subfamily A member 1 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5
Match NameE-valueIdentityDescription
SMESG000029534.10.000e+098.68SMESG000029534.1[more]
SMESG000056983.10.000e+047.01SMESG000056983.1[more]
SMESG000032896.10.000e+052.11SMESG000032896.1[more]
SMESG000032861.10.000e+051.53SMESG000032861.1[more]
SMESG000032896.10.000e+051.91SMESG000032896.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30014020 ID=SMED30014020|Name=ATP binding cassette subfamily A member 1|organism=Schmidtea mediterranea sexual|type=transcript|length=2356bp
TTTATTTTATAGCAGATAATTAACTATTGCATTTTTAAGATTAAATTTTT
TCTTAGATTTTTTTTTCCAGTAATTATGAATTCTATATTTACGAAACAGT
TGAAAGTGTTGCTTTGGAAAAATTTTAGATTGAAAAAACGAAAACCTATA
ACTTTGATTTCAGAAATTTTGGTACCTCTTTTAATTATCATCATTATAGT
GCCAGTGCGTAATTCAATTTTTAAATTTAAAATGGATCACTGCGAATTTA
AAGAAAAAAGTATGGCTTCTATGGGGTTTGTGCCATTTATTTTAGATTTC
TTTTGTACATTTAATACAACTTGTTACAATAAAACCCAAATTAATTGGAA
TGAGAATTATAGTAGTATTTATGCTTTTAAAATGTTTACGAAAAATCTAT
ACAATGTCTATCAAACTTTACCTAAAGAAAAGTTAACTGTTAATTCCTTA
ATTACATGGGCAACTAATCATAAATTTGAAATTGATCAATTAATAAGCAA
TATAATGCCAATTATTAAATTACTTTCCCCATTGATTGCAAGTTTAAAAG
AAGCAGATACCGAAAATTTAACAGCGTCTAAACCGATTATTATACAAATT
TTTAAAGTTTTTTGTGGATCAGATGAGAATGATTTTACAGAATTTTATTA
TAAATTTTCATCCATATCGACAAAAAATGTGTCCGGACAAACCAATGCTG
GTAGTCAATTTATGAATGAATCAAACGTAACTTGCGAAAGAAATTTTGAA
AATTTCTTTGGAAATTCTAATATATTCGATACTATTTCTTCGTGGGTATT
TGGGAAAATTTATTTCTCTCCTAATTCTCCGTTAACCAGAGAAATTATGC
GAAGAGCAAACATAACATTTGAAACTTTAGATTACATTCGGCTAGCGTCC
ATTGAATGGCGGTTGCATTTTCGTGATTGGATTAATGAAGCTGTCAATAA
CAGTAAATTAATTAATGAACTAAAATCCTGCAAATCTTGGTATTTTTATT
TCGACAATAATCTCTGTGAAACAGTCAATGCTGTATTGAATTTTCAAACT
ATTCAATCAATTCTAAATAAAATCTCCTTAATGTTCTCTTTACTGGAAAA
AACCTTAAATTGTACAGAATTAAATAAATTTATGCCAATAAATGAATCGA
TCACTGTCGAGAATTTCATCAAGCAGCCAATGAAAAGCGTTTTTGCCGTC
CTCGTCATTAATGATACATTTCGCTATCTGACACCATCGAATGCAACATT
TCTCAGCTATCAAATTCGAATCCCAGAAAATCAAATCGACTCTACGAAAC
ACTTTAAAGTCACCGATAAATTCTGGACCGCTGAACCCCGTCGGGAAACT
TTACGTGATTTCAAATACTACACAAGCGGATTCCTGTTGCTGCAGGAGGC
AATCGACCGGGCATTTATCGAGATCGTTACGAATAATGAAACAATCGATG
TCGGCTCGAGCATGCAAATCATGCCGTACCCGTGTTACGTTGATGACATG
TTCATCAGATTCATCACCAACATGATGCCGTTCATGTTGGTGATCGCCTG
GGTTCCCTCTGTCACCGGGCTGATCAAGAGCATCGTATATGAAAAAGAAA
GACGCCTAAAAGAATTTATGCGTGTAATGGGGTTAGGAAATTCCGTCCAT
TGGATTGGCTGGTTCCTATCAACAGTTGTCGTATTGATTTTCCCGGTTAC
TATCATGTCATTGCTTTTGATATATTCCTCGATTCTCTCCTTCTCTTGTT
TTGCAGTCGTTTTTCTGGTTTTACTTCTCTACGTCGTTTCTTTCATTTGC
CAGGTGTTTATGATCAGCCTGTTCTTCAGTAATGCCAACTTAGCCTCGGT
AGCCGGCGGCGTCATCTATTTCATTCTCTACATGCCGTTTGTCGTGTTTA
TCCGGATGCAGAGCGATCTGTCTACTGGATTCTATTATCTGGGCGGATTG
TCGGCACAAGTGGCTTTTTGTAACGCGATTAATTTCATTGGCTATTGGGA
GCAGTCGACTGAGGGAGCACATTTTGGGAATTTATTCGACGGGGCAATTA
TCGATTTGAAATTTGGGGTCGGTCATTGCATGCTGATGCTGATAGTAGAC
AGCGTGTTATATTTATCAGTGGCATGGTATGTGGAATCTGTATTTCCCGG
GCAATACGGGGTCGGTAAGGCCTGGTACTTTCTGTTCACCCGGAATTATT
GGCGGGCTAAGGAAAATATCAGTCTTGCACACGATATTAACAATAGTGCA
CAGCTAATTATCGATTATGATAGTGAGGGTAACTTTGAAAACGAATATAC
CGATCTACGTGTAGGAATATCGATTAGGAACCTAGTGAAAACATATCCTG
GAGCGA
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protein sequence of SMED30014020-orf-1

>SMED30014020-orf-1 ID=SMED30014020-orf-1|Name=SMED30014020-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=760bp
MNSIFTKQLKVLLWKNFRLKKRKPITLISEILVPLLIIIIIVPVRNSIFK
FKMDHCEFKEKSMASMGFVPFILDFFCTFNTTCYNKTQINWNENYSSIYA
FKMFTKNLYNVYQTLPKEKLTVNSLITWATNHKFEIDQLISNIMPIIKLL
SPLIASLKEADTENLTASKPIIIQIFKVFCGSDENDFTEFYYKFSSISTK
NVSGQTNAGSQFMNESNVTCERNFENFFGNSNIFDTISSWVFGKIYFSPN
SPLTREIMRRANITFETLDYIRLASIEWRLHFRDWINEAVNNSKLINELK
SCKSWYFYFDNNLCETVNAVLNFQTIQSILNKISLMFSLLEKTLNCTELN
KFMPINESITVENFIKQPMKSVFAVLVINDTFRYLTPSNATFLSYQIRIP
ENQIDSTKHFKVTDKFWTAEPRRETLRDFKYYTSGFLLLQEAIDRAFIEI
VTNNETIDVGSSMQIMPYPCYVDDMFIRFITNMMPFMLVIAWVPSVTGLI
KSIVYEKERRLKEFMRVMGLGNSVHWIGWFLSTVVVLIFPVTIMSLLLIY
SSILSFSCFAVVFLVLLLYVVSFICQVFMISLFFSNANLASVAGGVIYFI
LYMPFVVFIRMQSDLSTGFYYLGGLSAQVAFCNAINFIGYWEQSTEGAHF
GNLFDGAIIDLKFGVGHCMLMLIVDSVLYLSVAWYVESVFPGQYGVGKAW
YFLFTRNYWRAKENISLAHDINNSAQLIIDYDSEGNFENEYTDLRVGISI
RNLVKTYPGA
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: INTERPRO
TermDefinition
IPR026082ABCA
Vocabulary: molecular function
TermDefinition
GO:0000166nucleotide binding
GO:0005102signaling receptor binding
GO:0005215transporter activity
GO:0005515protein binding
GO:0005524ATP binding
GO:0005543phospholipid binding
GO:0005548phospholipid transporter activity
GO:0008509anion transmembrane transporter activity
GO:0015485cholesterol binding
GO:0016887ATPase activity
GO:0017127cholesterol transporter activity
GO:0019905syntaxin binding
GO:0031267small GTPase binding
GO:0034185apolipoprotein binding
GO:0034186apolipoprotein A-I binding
GO:0034188apolipoprotein A-I receptor activity
GO:0042626ATPase activity, coupled to transmembrane movement of substances
GO:0051117ATPase binding
GO:0090554phosphatidylcholine-translocating ATPase activity
GO:0090556phosphatidylserine-translocating ATPase activity
Vocabulary: biological process
TermDefinition
GO:0002790peptide secretion
GO:0006497protein lipidation
GO:0006629lipid metabolic process
GO:0006810transport
GO:0006911phagocytosis, engulfment
GO:0007040lysosome organization
GO:0007186G-protein coupled receptor signaling pathway
GO:0007584response to nutrient
GO:0008202steroid metabolic process
GO:0008203cholesterol metabolic process
GO:0010745negative regulation of macrophage derived foam cell differentiation
GO:0010875positive regulation of cholesterol efflux
GO:0010887negative regulation of cholesterol storage
GO:0015914phospholipid transport
GO:0015917aminophospholipid transport
GO:0016197endosomal transport
GO:0030301cholesterol transport
GO:0030819positive regulation of cAMP biosynthetic process
GO:0032367intracellular cholesterol transport
GO:0032489regulation of Cdc42 protein signal transduction
GO:0033344cholesterol efflux
GO:0033700phospholipid efflux
GO:0034380high-density lipoprotein particle assembly
GO:0034616response to laminar fluid shear stress
GO:0038027apolipoprotein A-I-mediated signaling pathway
GO:0042157lipoprotein metabolic process
GO:0042158lipoprotein biosynthetic process
GO:0042493response to drug
GO:0042632cholesterol homeostasis
GO:0043691reverse cholesterol transport
GO:0045332phospholipid translocation
GO:0050702interleukin-1 beta secretion
GO:0055085transmembrane transport
GO:0055091phospholipid homeostasis
GO:0055098response to low-density lipoprotein particle
GO:0060155platelet dense granule organization
GO:0071222cellular response to lipopolysaccharide
GO:0071300cellular response to retinoic acid
GO:0071397cellular response to cholesterol
GO:0090107regulation of high-density lipoprotein particle assembly
GO:0098656anion transmembrane transport
Vocabulary: cellular component
TermDefinition
GO:0005789endoplasmic reticulum membrane
GO:0005794Golgi apparatus
GO:0005886plasma membrane
GO:0005887integral component of plasma membrane
GO:0009897external side of plasma membrane
GO:0009986cell surface
GO:0016020membrane
GO:0016021integral component of membrane
GO:0030139endocytic vesicle
GO:0034364high-density lipoprotein particle
GO:0043231intracellular membrane-bounded organelle
GO:0045121membrane raft
GO:0045335phagocytic vesicle
GO:0048471perinuclear region of cytoplasm
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
NoneNo IPR availablePFAMPF12698ABC2_membrane_3coord: 437..685
e-value: 1.6E-19
score: 70.2
NoneNo IPR availablePANTHERPTHR19229:SF216ATP-BINDING CASSETTE, SUB-FAMILY A (ABC1), MEMBER 1Acoord: 217..757
coord: 6..74
NoneNo IPR availableTMHMMTMhelixcoord: 526..548
NoneNo IPR availableTMHMMTMhelixcoord: 663..685
NoneNo IPR availableTMHMMTMhelixcoord: 619..641
NoneNo IPR availableTMHMMTMhelixcoord: 587..609
NoneNo IPR availableTMHMMTMhelixcoord: 25..44
NoneNo IPR availableTMHMMTMhelixcoord: 553..575
NoneNo IPR availableTMHMMTMhelixcoord: 483..505
IPR026082ABC transporter APANTHERPTHR19229ATP-BINDING CASSETTE TRANSPORTER SUBFAMILY A ABCAcoord: 217..757
coord: 6..74