SMED30013976

Overview
NameSMED30013976
Smed IDSMED30013976
Length (bp)315
Neoblast Clusters

Zeng et. al., 2018



▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)



Explore this single cell expression dataset with our NB Cluster Shiny App



 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of SMED30013976 (SMED30013976) t-SNE clustered cells

Violin plots show distribution of expression levels for SMED30013976 (SMED30013976) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of SMED30013976 (SMED30013976) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for SMED30013976 (SMED30013976) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
Sort Descending | Sort Ascending | Only Non-Zero Values | Tile/Chart | Reset

Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Alignments
SMED30013976 aligns in the following genomic locations:
Alignment LocationAlignment Score
v31.012014:3704..4074 -886
Homology
[Close]
BLAST of SMED30013976 vs. Ensembl Human
Match: PI16 (peptidase inhibitor 16 [Source:HGNC Symbol;Acc:HGNC:21245])

HSP 1 Score: 83.5741 bits (205), Expect = 1.143e-19
Identity = 41/103 (39.81%), Postives = 58/103 (56.31%), Query Frame = -1 
Query:    4 GEDIKKGVDLWFIQSSGFTFSDNSCSL-PTCGHYTQLVWANSTEVGCGLSKCS----IDGIDLNLLVCNYAPGGNYVAEKPYKPGTACSECESGQDCSKYGLC 297
            G D+   ++ W  +   +  S  +CS    CGHYTQ+VWA +  +GCG   C     ++  ++ LLVCNY P GN   ++PY+ GT CS+C SG  C K  LC
Sbjct:   96 GMDVPLAMEEWHHEREHYNLSAATCSPGQMCGHYTQVVWAKTERIGCGSHFCEKLQGVEETNIELLVCNYEPPGNVKGKRPYQEGTPCSQCPSGYHC-KNSLC 197
[Close]
BLAST of SMED30013976 vs. Ensembl Human
Match: PI16 (peptidase inhibitor 16 [Source:HGNC Symbol;Acc:HGNC:21245])

HSP 1 Score: 83.5741 bits (205), Expect = 1.143e-19
Identity = 41/103 (39.81%), Postives = 58/103 (56.31%), Query Frame = -1 
Query:    4 GEDIKKGVDLWFIQSSGFTFSDNSCSL-PTCGHYTQLVWANSTEVGCGLSKCS----IDGIDLNLLVCNYAPGGNYVAEKPYKPGTACSECESGQDCSKYGLC 297
            G D+   ++ W  +   +  S  +CS    CGHYTQ+VWA +  +GCG   C     ++  ++ LLVCNY P GN   ++PY+ GT CS+C SG  C K  LC
Sbjct:   96 GMDVPLAMEEWHHEREHYNLSAATCSPGQMCGHYTQVVWAKTERIGCGSHFCEKLQGVEETNIELLVCNYEPPGNVKGKRPYQEGTPCSQCPSGYHC-KNSLC 197
[Close]
BLAST of SMED30013976 vs. Ensembl Human
Match: PI16 (peptidase inhibitor 16 [Source:HGNC Symbol;Acc:HGNC:21245])

HSP 1 Score: 83.5741 bits (205), Expect = 1.143e-19
Identity = 41/103 (39.81%), Postives = 58/103 (56.31%), Query Frame = -1 
Query:    4 GEDIKKGVDLWFIQSSGFTFSDNSCSL-PTCGHYTQLVWANSTEVGCGLSKCS----IDGIDLNLLVCNYAPGGNYVAEKPYKPGTACSECESGQDCSKYGLC 297
            G D+   ++ W  +   +  S  +CS    CGHYTQ+VWA +  +GCG   C     ++  ++ LLVCNY P GN   ++PY+ GT CS+C SG  C K  LC
Sbjct:   96 GMDVPLAMEEWHHEREHYNLSAATCSPGQMCGHYTQVVWAKTERIGCGSHFCEKLQGVEETNIELLVCNYEPPGNVKGKRPYQEGTPCSQCPSGYHC-KNSLC 197
[Close]
BLAST of SMED30013976 vs. Ensembl Human
Match: GLIPR1L1 (GLIPR1 like 1 [Source:HGNC Symbol;Acc:HGNC:28392])

HSP 1 Score: 77.7962 bits (190), Expect = 2.476e-18
Identity = 41/108 (37.96%), Postives = 58/108 (53.70%), Query Frame = -1 
Query:   16 KFVGEDI----------KKGVDLWFIQSSGFTFSDNSCSLPTCGHYTQLVWANSTEVGCGLSKC-SIDGIDLNLLVCNYAPGGNYVAEKPYKPGTACSECESGQDCSK 306
            ++VGE+I          +  +  W+ ++  + F   SCS   CGHYTQLVWANS  VGC ++ C ++ G    + VCNY P GN+    PY  G +CS C   + C K
Sbjct:   94 EYVGENIWLGGIKSFTPRHAITAWYNETQFYDFDSLSCSR-VCGHYTQLVWANSFYVGCAVAMCPNLGGASTAIFVCNYGPAGNFANMPPYVRGESCSLCSKEEKCVK 200
[Close]
BLAST of SMED30013976 vs. Ensembl Human
Match: GLIPR1L1 (GLIPR1 like 1 [Source:HGNC Symbol;Acc:HGNC:28392])

HSP 1 Score: 77.7962 bits (190), Expect = 2.822e-18
Identity = 41/108 (37.96%), Postives = 58/108 (53.70%), Query Frame = -1 
Query:   16 KFVGEDI----------KKGVDLWFIQSSGFTFSDNSCSLPTCGHYTQLVWANSTEVGCGLSKC-SIDGIDLNLLVCNYAPGGNYVAEKPYKPGTACSECESGQDCSK 306
            ++VGE+I          +  +  W+ ++  + F   SCS   CGHYTQLVWANS  VGC ++ C ++ G    + VCNY P GN+    PY  G +CS C   + C K
Sbjct:   94 EYVGENIWLGGIKSFTPRHAITAWYNETQFYDFDSLSCSR-VCGHYTQLVWANSFYVGCAVAMCPNLGGASTAIFVCNYGPAGNFANMPPYVRGESCSLCSKEEKCVK 200
[Close]
BLAST of SMED30013976 vs. Ensembl Celegans
Match: scl-10 (SCP-Like extracellular protein [Source:UniProtKB/TrEMBL;Acc:Q20609])

HSP 1 Score: 67.3958 bits (163), Expect = 6.743e-15
Identity = 33/70 (47.14%), Postives = 43/70 (61.43%), Query Frame = -1 
Query:    4 GHYTQLVWANSTEVGCGLSKCSIDGIDLN-LLVCNYAPGGNYVAEKPYKPGTACSECESGQDC-SKYGLC 207
            GH TQ+ WA + ++GCG+SKCS D      ++VC Y+P GNY+    YK G  CS C  G +C S  GLC
Sbjct:  142 GHATQMAWATTNKIGCGISKCSSDSFGTQYVVVCLYSPAGNYIGMDIYKSGETCSNCPDGTNCESSTGLC 211
[Close]
BLAST of SMED30013976 vs. Ensembl Celegans
Match: scl-14 (SCP-Like extracellular protein [Source:UniProtKB/TrEMBL;Acc:Q93444])

HSP 1 Score: 64.6994 bits (156), Expect = 6.806e-14
Identity = 33/95 (34.74%), Postives = 53/95 (55.79%), Query Frame = -1 
Query:    4 WFIQSSGFTFSDNSCSLPT----CGHYTQLVWANSTEVGCGLSKCSID--GIDLNLLVCNYAPGGNYVAEKPYKPGTACSECESGQDC-SKYGLC 267
            W  +   + +S N+ ++       GH TQ+ WA +  +GCG+  C +D  G++   +VC+Y P GNY+ +  Y  GT CS+C +G  C +  GLC
Sbjct:  113 WEKEFQDYGWSSNTLTMSLFNSGVGHATQMAWAKTNLIGCGVKNCGMDTNGMNKVAVVCHYQPQGNYLNQNIYTSGTTCSKCPAGTSCEAATGLC 207
[Close]
BLAST of SMED30013976 vs. Ensembl Celegans
Match: scl-5 (SCP-Like extracellular protein [Source:UniProtKB/TrEMBL;Acc:Q18543])

HSP 1 Score: 64.3142 bits (155), Expect = 9.416e-14
Identity = 36/100 (36.00%), Postives = 52/100 (52.00%), Query Frame = -1 
Query:    1 GVDLWFIQSSGFTFSDNSCSLPT----CGHYTQLVWANSTEVGCGLSKCSID--GIDLNLLVCNYAPGGNYVAEKPYKPGTACSECESGQDC-SKYGLCS 279
            G   W  +   + +S N+ S+       GH TQ+ WA +  +GCG+  C  D  G +   +VC Y P GNY+ +  Y  GT CS+C SG  C +  GLC+
Sbjct:  109 GSAAWEKEFQDYGWSSNTLSMSLFNTGIGHATQMAWAKTNLIGCGVKNCGKDTNGFNKVTVVCQYKPQGNYLNQNIYTSGTTCSKCPSGTSCEAATGLCA 208
[Close]
BLAST of SMED30013976 vs. Ensembl Celegans
Match: scl-11 (SCP-Like extracellular protein [Source:UniProtKB/TrEMBL;Acc:Q93746])

HSP 1 Score: 62.3882 bits (150), Expect = 5.000e-13
Identity = 30/72 (41.67%), Postives = 41/72 (56.94%), Query Frame = -1 
Query:    1 GHYTQLVWANSTEVGCGLSKCSID---GIDLNLLVCNYAPGGNYVAEKPYKPGTACSECESGQDCSKYGLCS 207
            GH TQ+ WAN+  +GCG+  C  D   G +   +VC Y   GNY+ +  Y+ GT C+ C SG  C   GLC+
Sbjct:  136 GHATQMAWANTFAIGCGVKNCGKDPSNGYNKVAVVCQYKTPGNYLNQPIYQQGTTCAACPSGTACDSSGLCA 207
[Close]
BLAST of SMED30013976 vs. Ensembl Celegans
Match: scl-2 (SCP-Like extracellular protein [Source:UniProtKB/TrEMBL;Acc:Q20603])

HSP 1 Score: 58.9214 bits (141), Expect = 8.473e-13
Identity = 31/71 (43.66%), Postives = 39/71 (54.93%), Query Frame = -1 
Query:    4 GHYTQLVWANSTEVGCGLSKCSIDGIDLN--LLVCNYAPGGNYVAEKPYKPGTACSECESGQDC-SKYGLC 207
            GH TQ+ WA S  +GCG+  C  D   LN   +VC Y P GN++ +  Y  G  CS C SG  C +  GLC
Sbjct:   11 GHATQMAWAKSNLIGCGVKDCGRDSNGLNKVTVVCQYKPQGNFINQYIYVSGATCSGCPSGTSCETSTGLC 81
[Close]
BLAST of SMED30013976 vs. Ensembl Fly
Match: CG8483 (gene:FBgn0038126 transcript:FBtr0082782)

HSP 1 Score: 63.929 bits (154), Expect = 4.758e-13
Identity = 35/98 (35.71%), Postives = 48/98 (48.98%), Query Frame = -1 
Query:    1 DIKKGVDLWFIQSSGFTFSDNSCSLPTCGHYTQLVWANSTEVGCGLSKCSIDGIDLNLLVCNYAPGGNYVAEKPYKPGTACSECESGQDCSKY-GLCS 291
            D    +  WF +   ++F D     P  GHY+QLVW  ++ VGCG ++         L VCNY PGGN V   PY+ G         +  S+Y GLC+
Sbjct:  119 DFPSRIQSWFNEVQKYSFGDAWS--PKTGHYSQLVWGETSLVGCGYAEYKDTSKYNKLYVCNYGPGGNVVGYNPYEVGKPSCSTYGMKPSSRYQGLCA 214
[Close]
BLAST of SMED30013976 vs. Ensembl Fly
Match: CG4270 (gene:FBgn0031407 transcript:FBtr0077754)

HSP 1 Score: 55.4546 bits (132), Expect = 1.394e-10
Identity = 24/65 (36.92%), Postives = 42/65 (64.62%), Query Frame = -1 
Query:   82 VDLWFIQSSGFTFSDNSCSLPTCGHYTQLVWANSTEVGCGLSKCSIDGIDLNLLVCNYAPGGNYV 276
            V++W+ + + + F + +  +PT GH+TQL+W +S E+G G+++ +    D   +VCNY P GN V
Sbjct:  100 VEMWYREINSYDF-NKAQFVPTAGHFTQLIWKSSVEMGSGVARKA----DRTWVVCNYNPPGNVV 159
[Close]
BLAST of SMED30013976 vs. Ensembl Fly
Match: CG32679 (gene:FBgn0052679 transcript:FBtr0071469)

HSP 1 Score: 52.373 bits (124), Expect = 3.760e-9
Identity = 31/101 (30.69%), Postives = 51/101 (50.50%), Query Frame = -1 
Query:    1 IKKGVDLWFIQSSGFTFSD----NSCSLPTCGHYTQLVWANSTEVGCGLSKCS-IDGIDLNLLVCNYAPGGNYVAEKPYKPGTACSECESGQDCSKYGLCS 288
            +++ +  WF ++   T  D         P  GH+T +V   +  VGC +++ +  + +   LL CNYA   N V    Y+ GTA SEC +G++ +   LCS
Sbjct:  143 LRQRIAAWFDENRDATSGDMEDYQMRGGPAIGHFTTMVNERNNRVGCAIARFTDANNVQATLLACNYAVT-NVVNNPVYRAGTAASECTTGRNSNYPNLCS 242
[Close]
BLAST of SMED30013976 vs. Ensembl Fly
Match: CG4270 (gene:FBgn0031407 transcript:FBtr0077755)

HSP 1 Score: 43.8986 bits (102), Expect = 2.135e-6
Identity = 15/43 (34.88%), Postives = 31/43 (72.09%), Query Frame = -1 
Query:  148 VDLWFIQSSGFTFSDNSCSLPTCGHYTQLVWANSTEVGCGLSK 276
            V++W+ + + + F + +  +PT GH+TQL+W +S E+G G+++
Sbjct:  100 VEMWYREINSYDF-NKAQFVPTAGHFTQLIWKSSVEMGSGVAR 141
[Close]
BLAST of SMED30013976 vs. Ensembl Zebrafish
Match: r3hdml (R3H domain containing-like [Source:ZFIN;Acc:ZDB-GENE-090313-275])

HSP 1 Score: 73.559 bits (179), Expect = 9.638e-17
Identity = 41/95 (43.16%), Postives = 52/95 (54.74%), Query Frame = -1 
Query:   16 VDLWFIQSSGFTFSDNSCSLPTCGHYTQLVWANSTEVGCGLSKCSIDGI------DLNLLVCNYAPGGNYVAEKPYKPGTACSECES--GQDCSK 276
            V  W+ +   F++    CS   C HYTQ+VWA S ++GC + KCS   +         LLVCNYA  GN+V E PYK G  CS C S  G  C+K
Sbjct:  138 VKSWYDERHSFSYPSR-CSGSVCTHYTQMVWAASNKIGCAIKKCSDIFVFGSMWKQATLLVCNYAIKGNWVGEAPYKIGRPCSACPSSYGGSCNK 231
[Close]
BLAST of SMED30013976 vs. Ensembl Zebrafish
Match: r3hdml (R3H domain containing-like [Source:ZFIN;Acc:ZDB-GENE-090313-275])

HSP 1 Score: 73.559 bits (179), Expect = 9.638e-17
Identity = 41/95 (43.16%), Postives = 52/95 (54.74%), Query Frame = -1 
Query:   16 VDLWFIQSSGFTFSDNSCSLPTCGHYTQLVWANSTEVGCGLSKCSIDGI------DLNLLVCNYAPGGNYVAEKPYKPGTACSECES--GQDCSK 276
            V  W+ +   F++    CS   C HYTQ+VWA S ++GC + KCS   +         LLVCNYA  GN+V E PYK G  CS C S  G  C+K
Sbjct:  138 VKSWYDERHSFSYPSR-CSGSVCTHYTQMVWAASNKIGCAIKKCSDIFVFGSMWKQATLLVCNYAIKGNWVGEAPYKIGRPCSACPSSYGGSCNK 231
[Close]
BLAST of SMED30013976 vs. Ensembl Zebrafish
Match: CU914487.1 (peptidase inhibitor 16-like [Source:NCBI gene;Acc:101883528])

HSP 1 Score: 70.8626 bits (172), Expect = 1.805e-16
Identity = 38/96 (39.58%), Postives = 58/96 (60.42%), Query Frame = -1 
Query:   40 FVGE---DIKKGVDLWFIQSSGFTFSDNSCSL-PTCGHYTQLVWANSTEVGCGLSKC-SIDGIDLN---LLVCNYAPGGNYVAEKPYKPGTACSEC 303
            FVG    +  K V  WF ++  + ++ N C+    CGHYTQLVWAN+T++GC    C +++ +      LL+C+Y P GN   +KPY+ G +CS+C
Sbjct:   42 FVGTGPFNATKAVMDWFNENLDYNYNTNDCAEDKMCGHYTQLVWANTTKIGCASYFCDTLEKLHFEKATLLICDYYPQGNIEGQKPYESGESCSKC 137
[Close]
BLAST of SMED30013976 vs. Ensembl Zebrafish
Match: glipr1a (GLI pathogenesis-related 1a [Source:ZFIN;Acc:ZDB-GENE-110309-2])

HSP 1 Score: 70.4774 bits (171), Expect = 1.114e-15
Identity = 35/99 (35.35%), Postives = 50/99 (50.51%), Query Frame = -1 
Query:   16 IKKGVDLWFIQSSGFTFSDNSCS-LPTCGHYTQLVWANSTEVGCGLSKC-------SIDGIDLNLLVCNYAPGGNYVAEKPYKPGTACSECESGQDCSK 288
            +K  V  W  +   + +++N C+    CGHYTQ+VWA+S +VGC +  C           I   + VCNYA  GN+    PYK G +CS C     C +
Sbjct:  109 VKSAVFSWVNELKDYNYNNNQCNDKKVCGHYTQVVWADSYKVGCAVQTCPNGVAETHFSNIQGVIFVCNYATAGNFAGRSPYKQGASCSGCGGSDKCER 207
[Close]
BLAST of SMED30013976 vs. Ensembl Zebrafish
Match: glipr1a (GLI pathogenesis-related 1a [Source:ZFIN;Acc:ZDB-GENE-110309-2])

HSP 1 Score: 70.0922 bits (170), Expect = 2.261e-15
Identity = 35/99 (35.35%), Postives = 50/99 (50.51%), Query Frame = -1 
Query:   16 IKKGVDLWFIQSSGFTFSDNSCS-LPTCGHYTQLVWANSTEVGCGLSKC-------SIDGIDLNLLVCNYAPGGNYVAEKPYKPGTACSECESGQDCSK 288
            +K  V  W  +   + +++N C+    CGHYTQ+VWA+S +VGC +  C           I   + VCNYA  GN+    PYK G +CS C     C +
Sbjct:  117 VKSAVFSWVNELKDYNYNNNQCNDKKVCGHYTQVVWADSYKVGCAVQTCPNGVAETHFSNIQGVIFVCNYATAGNFAGRSPYKQGASCSGCGGSDKCER 215
[Close]
BLAST of SMED30013976 vs. Ensembl Xenopus
Match: ENSXETT00000036788.1 (pep primary_assembly:Xenopus_tropicalis_v9.1:KV464547.1:593:5826:1 gene:ENSXETG00000015856.1 transcript:ENSXETT00000036788.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 90.1225 bits (222), Expect = 3.423e-22
Identity = 44/103 (42.72%), Postives = 59/103 (57.28%), Query Frame = -1 
Query:   13 DIKKGVDLWFIQSSGFTFSDNSCSL-PTCGHYTQLVWANSTEVGCGLSKC-SIDGID---LNLLVCNYAPGGNYVAEKPYKPGTACSECES-----GQDCSKY 291
            D+  G+D W  +   + F+   C     CGHYTQ+VWA +  VGCG + C  ++G+D   + LLVCNY P GN+  E PYK G+ C+EC S     G  C KY
Sbjct:  100 DVALGLDDWHKERGYYNFTTGMCQEGQMCGHYTQMVWAGTERVGCGQNFCPKLEGVDDENMYLLVCNYEPPGNFEGESPYKEGSRCTECPSDHVCIGSLCGKY 202
[Close]
BLAST of SMED30013976 vs. Ensembl Xenopus
Match: crispld2 (cysteine-rich secretory protein LCCL domain containing 2 [Source:NCBI gene;Acc:613091])

HSP 1 Score: 71.633 bits (174), Expect = 1.955e-15
Identity = 36/94 (38.30%), Postives = 50/94 (53.19%), Query Frame = -1 
Query:   40 VDLWFIQSSGFTFS---------DNSCSLPTCGHYTQLVWANSTEVGCGLSKCSIDGI------DLNLLVCNYAPGGNYVAEKPYKPGTACSEC 276
            V  W+ +   +T+             CS P C HYTQ+VWA +T+VGC ++ C    +      +   LVCNY+P GN++ E PYK G  CSEC
Sbjct:  129 VQSWYDEVKDYTYPYPHECNPYCPERCSGPMCTHYTQIVWATTTKVGCAVNVCKRMNVWGDIWENAVYLVCNYSPKGNWIGEAPYKNGRPCSEC 222
[Close]
BLAST of SMED30013976 vs. Ensembl Xenopus
Match: crispld2 (cysteine-rich secretory protein LCCL domain containing 2 [Source:NCBI gene;Acc:613091])

HSP 1 Score: 71.2478 bits (173), Expect = 2.424e-15
Identity = 36/94 (38.30%), Postives = 50/94 (53.19%), Query Frame = -1 
Query:   40 VDLWFIQSSGFTFS---------DNSCSLPTCGHYTQLVWANSTEVGCGLSKCSIDGI------DLNLLVCNYAPGGNYVAEKPYKPGTACSEC 276
            V  W+ +   +T+             CS P C HYTQ+VWA +T+VGC ++ C    +      +   LVCNY+P GN++ E PYK G  CSEC
Sbjct:  129 VQSWYDEVKDYTYPYPHECNPYCPERCSGPMCTHYTQIVWATTTKVGCAVNVCKRMNVWGDIWENAVYLVCNYSPKGNWIGEAPYKNGRPCSEC 222
[Close]
BLAST of SMED30013976 vs. Ensembl Xenopus
Match: crispld2 (cysteine-rich secretory protein LCCL domain containing 2 [Source:NCBI gene;Acc:613091])

HSP 1 Score: 71.2478 bits (173), Expect = 2.732e-15
Identity = 36/94 (38.30%), Postives = 50/94 (53.19%), Query Frame = -1 
Query:   40 VDLWFIQSSGFTFS---------DNSCSLPTCGHYTQLVWANSTEVGCGLSKCSIDGI------DLNLLVCNYAPGGNYVAEKPYKPGTACSEC 276
            V  W+ +   +T+             CS P C HYTQ+VWA +T+VGC ++ C    +      +   LVCNY+P GN++ E PYK G  CSEC
Sbjct:  129 VQSWYDEVKDYTYPYPHECNPYCPERCSGPMCTHYTQIVWATTTKVGCAVNVCKRMNVWGDIWENAVYLVCNYSPKGNWIGEAPYKNGRPCSEC 222
[Close]
BLAST of SMED30013976 vs. Ensembl Xenopus
Match: CRISPLD1 (cysteine-rich secretory protein LCCL domain containing 1 [Source:NCBI gene;Acc:100490431])

HSP 1 Score: 66.2402 bits (160), Expect = 1.480e-13
Identity = 32/72 (44.44%), Postives = 41/72 (56.94%), Query Frame = -1 
Query:   40 CSLPTCGHYTQLVWANSTEVGCGLSKCSIDGIDLNL----------LVCNYAPGGNYVAEKPYKPGTACSEC 225
            CS P C HYTQLVWA S+ +GC ++ C     ++N+          LVCNY+P GN+    PYK G  CS C
Sbjct:  160 CSGPVCTHYTQLVWATSSRIGCAINLCH----NMNVWGQIWPKAIYLVCNYSPKGNWWGHAPYKHGHPCSAC 227
[Close]
BLAST of SMED30013976 vs. Ensembl Mouse
Match: Glipr1l1 (GLI pathogenesis-related 1 like 1 [Source:MGI Symbol;Acc:MGI:1916536])

HSP 1 Score: 82.8037 bits (203), Expect = 1.980e-20
Identity = 45/111 (40.54%), Postives = 63/111 (56.76%), Query Frame = -1 
Query:    1 FVGEDIKKG---------VDLWFIQSSGFTFSDNSCSLPTCGHYTQLVWANSTEVGCGLSKC-SIDGIDLNLLVCNYAPGGNYVAEKPYKPGTACSECESGQDCSKYGLCS 303
            F+GE+I  G         V  W+ +S  F F  N+CS   CGHYTQ+VWA + ++GC +S C ++ G    L VCNY+P GN++  +PY  G +CS C  GQ   +  LC 
Sbjct:  103 FIGENIYLGRIETQPEDVVINWYNESKYFNFDFNTCS-EMCGHYTQVVWAKTVKIGCAVSNCPNLKGFSAGLFVCNYSPAGNFIGFRPYTRGDSCSMC--GQKTCENSLCR 210
[Close]
BLAST of SMED30013976 vs. Ensembl Mouse
Match: Pi16 (peptidase inhibitor 16 [Source:MGI Symbol;Acc:MGI:1921366])

HSP 1 Score: 80.1073 bits (196), Expect = 1.671e-18
Identity = 40/103 (38.83%), Postives = 55/103 (53.40%), Query Frame = -1 
Query:    4 GEDIKKGVDLWFIQSSGFTFSDNSCSL-PTCGHYTQLVWANSTEVGCGLSKCS----IDGIDLNLLVCNYAPGGNYVAEKPYKPGTACSECESGQDCSKYGLC 297
            G D+   V  W  +   + FS  +C     CGHYTQ+VW+ +  +GCG   C     ++  +++LLVCNY P GN    KPY+ GT CS+C  G  C    LC
Sbjct:   98 GMDVPLAVGNWHEEHEYYNFSTATCDPNQMCGHYTQVVWSKTERIGCGSHFCETLQGVEEANIHLLVCNYEPPGNVKGRKPYQEGTPCSQCPLGYSCEN-SLC 199
[Close]
BLAST of SMED30013976 vs. Ensembl Mouse
Match: Pi16 (peptidase inhibitor 16 [Source:MGI Symbol;Acc:MGI:1921366])

HSP 1 Score: 76.6406 bits (187), Expect = 5.388e-18
Identity = 38/98 (38.78%), Postives = 53/98 (54.08%), Query Frame = -1 
Query:   19 GEDIKKGVDLWFIQSSGFTFSDNSCSL-PTCGHYTQLVWANSTEVGCGLSKCS----IDGIDLNLLVCNYAPGGNYVAEKPYKPGTACSECESGQDCS 297
            G D+   V  W  +   + FS  +C     CGHYTQ+VW+ +  +GCG   C     ++  +++LLVCNY P GN    KPY+ GT CS+C  G  C 
Sbjct:   98 GMDVPLAVGNWHEEHEYYNFSTATCDPNQMCGHYTQVVWSKTERIGCGSHFCETLQGVEEANIHLLVCNYEPPGNVKGRKPYQEGTPCSQCPLGYSCE 195
[Close]
BLAST of SMED30013976 vs. Ensembl Mouse
Match: Pi16 (peptidase inhibitor 16 [Source:MGI Symbol;Acc:MGI:1921366])

HSP 1 Score: 76.6406 bits (187), Expect = 7.691e-18
Identity = 38/98 (38.78%), Postives = 53/98 (54.08%), Query Frame = -1 
Query:   19 GEDIKKGVDLWFIQSSGFTFSDNSCSL-PTCGHYTQLVWANSTEVGCGLSKCS----IDGIDLNLLVCNYAPGGNYVAEKPYKPGTACSECESGQDCS 297
            G D+   V  W  +   + FS  +C     CGHYTQ+VW+ +  +GCG   C     ++  +++LLVCNY P GN    KPY+ GT CS+C  G  C 
Sbjct:   98 GMDVPLAVGNWHEEHEYYNFSTATCDPNQMCGHYTQVVWSKTERIGCGSHFCETLQGVEEANIHLLVCNYEPPGNVKGRKPYQEGTPCSQCPLGYSCE 195
[Close]
BLAST of SMED30013976 vs. Ensembl Mouse
Match: Pi16 (peptidase inhibitor 16 [Source:MGI Symbol;Acc:MGI:1921366])

HSP 1 Score: 76.6406 bits (187), Expect = 7.691e-18
Identity = 38/98 (38.78%), Postives = 53/98 (54.08%), Query Frame = -1 
Query:   19 GEDIKKGVDLWFIQSSGFTFSDNSCSL-PTCGHYTQLVWANSTEVGCGLSKCS----IDGIDLNLLVCNYAPGGNYVAEKPYKPGTACSECESGQDCS 297
            G D+   V  W  +   + FS  +C     CGHYTQ+VW+ +  +GCG   C     ++  +++LLVCNY P GN    KPY+ GT CS+C  G  C 
Sbjct:   98 GMDVPLAVGNWHEEHEYYNFSTATCDPNQMCGHYTQVVWSKTERIGCGSHFCETLQGVEEANIHLLVCNYEPPGNVKGRKPYQEGTPCSQCPLGYSCE 195
[Close]
BLAST of SMED30013976 vs. UniProt/SwissProt
Match: sp|Q9DAG6|GPRL1_MOUSE (GLIPR1-like protein 1 OS=Mus musculus OX=10090 GN=Glipr1l1 PE=1 SV=1)

HSP 1 Score: 82.8037 bits (203), Expect = 1.385e-19
Identity = 45/111 (40.54%), Postives = 63/111 (56.76%), Query Frame = -1 
Query:    1 FVGEDIKKG---------VDLWFIQSSGFTFSDNSCSLPTCGHYTQLVWANSTEVGCGLSKC-SIDGIDLNLLVCNYAPGGNYVAEKPYKPGTACSECESGQDCSKYGLCS 303
            F+GE+I  G         V  W+ +S  F F  N+CS   CGHYTQ+VWA + ++GC +S C ++ G    L VCNY+P GN++  +PY  G +CS C  GQ   +  LC 
Sbjct:  103 FIGENIYLGRIETQPEDVVINWYNESKYFNFDFNTCS-EMCGHYTQVVWAKTVKIGCAVSNCPNLKGFSAGLFVCNYSPAGNFIGFRPYTRGDSCSMC--GQKTCENSLCR 210
[Close]
BLAST of SMED30013976 vs. UniProt/SwissProt
Match: sp|Q6UXB8|PI16_HUMAN (Peptidase inhibitor 16 OS=Homo sapiens OX=9606 GN=PI16 PE=1 SV=1)

HSP 1 Score: 83.5741 bits (205), Expect = 5.488e-19
Identity = 41/103 (39.81%), Postives = 58/103 (56.31%), Query Frame = -1 
Query:    4 GEDIKKGVDLWFIQSSGFTFSDNSCSL-PTCGHYTQLVWANSTEVGCGLSKCS----IDGIDLNLLVCNYAPGGNYVAEKPYKPGTACSECESGQDCSKYGLC 297
            G D+   ++ W  +   +  S  +CS    CGHYTQ+VWA +  +GCG   C     ++  ++ LLVCNY P GN   ++PY+ GT CS+C SG  C K  LC
Sbjct:   96 GMDVPLAMEEWHHEREHYNLSAATCSPGQMCGHYTQVVWAKTERIGCGSHFCEKLQGVEETNIELLVCNYEPPGNVKGKRPYQEGTPCSQCPSGYHC-KNSLC 197
[Close]
BLAST of SMED30013976 vs. UniProt/SwissProt
Match: sp|Q58D34|PI16_BOVIN (Peptidase inhibitor 16 OS=Bos taurus OX=9913 GN=PI16 PE=2 SV=1)

HSP 1 Score: 82.0333 bits (201), Expect = 2.138e-18
Identity = 40/103 (38.83%), Postives = 58/103 (56.31%), Query Frame = -1 
Query:    4 GEDIKKGVDLWFIQSSGFTFSDNSCSL-PTCGHYTQLVWANSTEVGCGLSKCS----IDGIDLNLLVCNYAPGGNYVAEKPYKPGTACSECESGQDCSKYGLC 297
            G D+   ++ W  +   +  S  SC+    CGHYTQ+VWA +  +GCG   C     ++  +++LLVCNY P GN   ++PY+ GT CS+C  G  C K  LC
Sbjct:   96 GLDVPLAMEEWHHEREHYNLSAISCAAGQMCGHYTQVVWAKTERIGCGSHFCEKLQGVEETNIHLLVCNYEPPGNVKGQRPYQEGTPCSQCPLGYHC-KNSLC 197
[Close]
BLAST of SMED30013976 vs. UniProt/SwissProt
Match: sp|Q32LB5|GPRL1_BOVIN (GLIPR1-like protein 1 OS=Bos taurus OX=9913 GN=GLIPR1L1 PE=1 SV=1)

HSP 1 Score: 78.9518 bits (193), Expect = 4.757e-18
Identity = 39/84 (46.43%), Postives = 53/84 (63.10%), Query Frame = -1 
Query:   37 KKGVDLWFIQSSGFTFSDNSCSLPTCGHYTQLVWANSTEVGCGLSKC-SIDGIDLNLLVCNYAPGGNYVAEKPYKPGTACSECE 285
            K  +++W+ +   + F+  SCS   CGHYTQ+VWA S +VGC ++ C ++   D  LLVCNYAP GNY    PY  GT CS C+
Sbjct:  112 KFAINMWYDERKFYDFNTRSCSQ-VCGHYTQVVWAYSYKVGCAVAVCPNLGSPDSALLVCNYAPAGNYPNMSPYTNGTPCSMCQ 194
[Close]
BLAST of SMED30013976 vs. UniProt/SwissProt
Match: sp|Q9ET66|PI16_MOUSE (Peptidase inhibitor 16 OS=Mus musculus OX=10090 GN=Pi16 PE=1 SV=2)

HSP 1 Score: 80.1073 bits (196), Expect = 1.169e-17
Identity = 40/103 (38.83%), Postives = 55/103 (53.40%), Query Frame = -1 
Query:    4 GEDIKKGVDLWFIQSSGFTFSDNSCSL-PTCGHYTQLVWANSTEVGCGLSKCS----IDGIDLNLLVCNYAPGGNYVAEKPYKPGTACSECESGQDCSKYGLC 297
            G D+   V  W  +   + FS  +C     CGHYTQ+VW+ +  +GCG   C     ++  +++LLVCNY P GN    KPY+ GT CS+C  G  C    LC
Sbjct:   98 GMDVPLAVGNWHEEHEYYNFSTATCDPNQMCGHYTQVVWSKTERIGCGSHFCETLQGVEEANIHLLVCNYEPPGNVKGRKPYQEGTPCSQCPLGYSCEN-SLC 199
[Close]
BLAST of SMED30013976 vs. TrEMBL
Match: C3ZIM9 (SCP domain-containing protein (Fragment) OS=Branchiostoma floridae OX=7739 GN=BRAFLDRAFT_247125 PE=4 SV=1)

HSP 1 Score: 93.2041 bits (230), Expect = 1.266e-21
Identity = 53/118 (44.92%), Postives = 69/118 (58.47%), Query Frame = -1 
Query:    4 NVAKFVGEDIKKGV---------DLWFIQSSGFTFSDNSC-SLPTCGHYTQLVWANSTEVGCGLSKCSIDGI----DLNLLVCNYAPGGNYVAEKPYKPGTACSECESGQDCSKYGLC 315
            N A  VGE+I  G          + W  + S +T+S NSC S   CGHYTQ+VWA S ++GCG+  CS  G     + NL+VCNYAP GN+V +KPY  GT C++C +G D     LC
Sbjct:   61 NYAGSVGENIYAGTGSYTAGSETENWHSEVSDYTYSSNSCRSGAVCGHYTQVVWATSKKLGCGVKLCSTLGTVNWSNANLVVCNYAPSGNFVGQKPYITGTPCTQCANGNDNCSDKLC 178
[Close]
BLAST of SMED30013976 vs. TrEMBL
Match: C3ZIM7 (SCP domain-containing protein (Fragment) OS=Branchiostoma floridae OX=7739 GN=BRAFLDRAFT_247050 PE=4 SV=1)

HSP 1 Score: 93.5893 bits (231), Expect = 1.294e-21
Identity = 53/118 (44.92%), Postives = 69/118 (58.47%), Query Frame = -1 
Query:    4 NVAKFVGEDIKKGV---------DLWFIQSSGFTFSDNSC-SLPTCGHYTQLVWANSTEVGCGLSKCSIDGI----DLNLLVCNYAPGGNYVAEKPYKPGTACSECESGQDCSKYGLC 315
            N A  VGE+I  G          + W  + S +T+S NSC S   CGHYTQ+VWA S ++GCG+  CS  G     + NL+VCNYAP GN+V +KPY  GT C++C +G D     LC
Sbjct:   61 NYAGSVGENIYAGTGSYTAGSETENWHSEVSDYTYSSNSCRSGAVCGHYTQVVWATSKKLGCGVKLCSTLGTVNWSNANLVVCNYAPAGNFVGQKPYISGTPCTQCANGNDNCSDKLC 178
[Close]
BLAST of SMED30013976 vs. TrEMBL
Match: T2MBL6 (Peptidase inhibitor 16 (Fragment) OS=Hydra vulgaris OX=6087 GN=PI16 PE=2 SV=1)

HSP 1 Score: 98.2117 bits (243), Expect = 1.337e-21
Identity = 46/97 (47.42%), Postives = 59/97 (60.82%), Query Frame = -1 
Query:    1 DIKKGVDLWFIQSSGFTFSDNSCSLPTCGHYTQLVWANSTEVGCGLSKCSIDGIDLNLLVCNYAPGGNYVAEKPYKPGTACSECESGQDCSKYGLCS 291
            D+ +GV  WF +S  + F    CS   C  YTQ+VW  S ++GCG  +C     D  +LVCNYAPGGNYV ++PYK G +CSEC SG  C    LC+
Sbjct:  193 DVYEGVKRWFSESKSYNFLTGQCS-GKCTLYTQMVWWESNKLGCGAKRCG----DRTILVCNYAPGGNYVGQRPYKTGKSCSECPSGLLCED-NLCT 283
[Close]
BLAST of SMED30013976 vs. TrEMBL
Match: C3Z2D9 (SCP domain-containing protein (Fragment) OS=Branchiostoma floridae OX=7739 GN=BRAFLDRAFT_203586 PE=4 SV=1)

HSP 1 Score: 93.2041 bits (230), Expect = 1.386e-21
Identity = 53/118 (44.92%), Postives = 69/118 (58.47%), Query Frame = -1 
Query:    4 NVAKFVGEDIKKGV---------DLWFIQSSGFTFSDNSC-SLPTCGHYTQLVWANSTEVGCGLSKCSIDGI----DLNLLVCNYAPGGNYVAEKPYKPGTACSECESGQDCSKYGLC 315
            N A  VGE+I  G          + W  + S +T+S NSC S   CGHYTQ+VWA S ++GCG+  CS  G     + NL+VCNYAP GN+V +KPY  GT C++C +G D     LC
Sbjct:   61 NYAGSVGENIYAGTGSYTAGSETENWHSEVSDYTYSSNSCRSGAVCGHYTQVVWATSKKLGCGVKLCSTLGTVNWSNANLVVCNYAPSGNFVGQKPYISGTPCTQCANGNDNCSDKLC 178
[Close]
BLAST of SMED30013976 vs. TrEMBL
Match: A0A3P6I532 (SCP domain-containing protein OS=Mesocestoides corti OX=53468 GN=MCOS_LOCUS8509 PE=3 SV=1)

HSP 1 Score: 92.0485 bits (227), Expect = 2.080e-21
Identity = 44/99 (44.44%), Postives = 63/99 (63.64%), Query Frame = -1 
Query:   16 EDIKKGVDLWFIQSSGFTFSDNSCSLPTCGHYTQLVWANSTEVGCGLSKCSIDGID------LNLLVCNYAPGGNYVAEKPYKPGTACSECESGQDCSK 294
            +   K  + W+ +   +T+S N CS   CGHYTQ+VWA++T +GC + +C  D ++      + L+VC YAPGGNYV EKPY  G +CSEC +G  CS+
Sbjct:   42 QSFTKMAESWYNEVVNYTYSSNDCSY-VCGHYTQMVWASTTVLGCAMQRC--DSLEPGWTPPVYLMVCQYAPGGNYVGEKPYTSGRSCSECPAGYSCSQ 137
[Close]
BLAST of SMED30013976 vs. Ensembl Cavefish
Match: ENSAMXT00000036030.1 (peptidase inhibitor 16 [Source:NCBI gene;Acc:103029846])

HSP 1 Score: 85.5001 bits (210), Expect = 1.960e-21
Identity = 39/89 (43.82%), Postives = 60/89 (67.42%), Query Frame = -1 
Query:   40 DIKKGVDLWFIQSSGFTFSDNSCSL-PTCGHYTQLVWANSTEVGCGLSKC-SIDGI---DLNLLVCNYAPGGNYVAEKPYKPGTACSEC 291
            DI+K +  WF++   +++ +N+C+    CGHYTQ+VWA + EVGCG   C +++ +   +  LLVCNY P GNY+ +KPY+ G  CS+C
Sbjct:   95 DIEKALSDWFMEHKHYSYDNNTCAENEMCGHYTQMVWAKTKEVGCGSHLCETVEALGFKNATLLVCNYLPLGNYMGQKPYQVGEQCSKC 183
[Close]
BLAST of SMED30013976 vs. Ensembl Cavefish
Match: ENSAMXT00000031557.1 (peptidase inhibitor 16 [Source:NCBI gene;Acc:103029846])

HSP 1 Score: 85.5001 bits (210), Expect = 2.488e-21
Identity = 39/89 (43.82%), Postives = 60/89 (67.42%), Query Frame = -1 
Query:   40 DIKKGVDLWFIQSSGFTFSDNSCSL-PTCGHYTQLVWANSTEVGCGLSKC-SIDGI---DLNLLVCNYAPGGNYVAEKPYKPGTACSEC 291
            DI+K +  WF++   +++ +N+C+    CGHYTQ+VWA + EVGCG   C +++ +   +  LLVCNY P GNY+ +KPY+ G  CS+C
Sbjct:   95 DIEKALSDWFMEHKHYSYDNNTCAENEMCGHYTQMVWAKTKEVGCGSHLCETVEALGFKNATLLVCNYLPLGNYMGQKPYQVGEQCSKC 183
[Close]
BLAST of SMED30013976 vs. Ensembl Cavefish
Match: ENSAMXT00000029824.1 (peptidase inhibitor 16 [Source:NCBI gene;Acc:103029846])

HSP 1 Score: 85.1149 bits (209), Expect = 4.109e-21
Identity = 39/89 (43.82%), Postives = 60/89 (67.42%), Query Frame = -1 
Query:   40 DIKKGVDLWFIQSSGFTFSDNSCSL-PTCGHYTQLVWANSTEVGCGLSKC-SIDGI---DLNLLVCNYAPGGNYVAEKPYKPGTACSEC 291
            DI+K +  WF++   +++ +N+C+    CGHYTQ+VWA + EVGCG   C +++ +   +  LLVCNY P GNY+ +KPY+ G  CS+C
Sbjct:   95 DIEKALSDWFMEHKHYSYDNNTCAENEMCGHYTQMVWAKTKEVGCGSHLCETVEALGFKNATLLVCNYLPLGNYMGQKPYQVGEQCSKC 183
[Close]
BLAST of SMED30013976 vs. Ensembl Cavefish
Match: r3hdml (R3H domain containing like [Source:NCBI gene;Acc:103046222])

HSP 1 Score: 73.559 bits (179), Expect = 7.522e-17
Identity = 41/118 (34.75%), Postives = 66/118 (55.93%), Query Frame = -1 
Query:   16 NVAKFVGEDI-------KKGVDL---WFIQSSGFTFSDNSCSLPTCGHYTQLVWANSTEVGCGLSKCSIDGI------DLNLLVCNYAPGGNYVAEKPYKPGTACSECES--GQDCSK 315
            +V K++G+++       +  ++L   W  + + F++  N C+   C HYTQ+VWA++  +GC +++CS   +         LLVCNY+  GN+V E PYK G  CS C S  G  C+K
Sbjct:  116 HVMKYMGQNLSISSGRYRSVIELVRSWHDEKNSFSY-PNRCTGSVCSHYTQMVWASTNRIGCAINRCSNMYVFGSTWKQATLLVCNYSIKGNWVGEAPYKTGKPCSACPSVYGGSCNK 232
[Close]
BLAST of SMED30013976 vs. Ensembl Cavefish
Match: crispld2 (cysteine-rich secretory protein LCCL domain containing 2 [Source:ZFIN;Acc:ZDB-GENE-130131-1])

HSP 1 Score: 70.8626 bits (172), Expect = 2.225e-15
Identity = 32/68 (47.06%), Postives = 41/68 (60.29%), Query Frame = -1 
Query:   40 CSLPTCGHYTQLVWANSTEVGCGLSKCSIDGI------DLNLLVCNYAPGGNYVAEKPYKPGTACSEC 225
            CS P C HYTQLVWA ++ VGC +  CS   +      +   LVCNY+P GN++ E PY  G  CS+C
Sbjct:  159 CSGPMCTHYTQLVWATTSRVGCAVHTCSRMNVWGEIWENAIYLVCNYSPKGNWIGEAPYAHGRPCSQC 226
[Close]
BLAST of SMED30013976 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000000374.1 (pep scaffold:Pmarinus_7.0:GL476650:75849:87118:-1 gene:ENSPMAG00000000334.1 transcript:ENSPMAT00000000374.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 73.559 bits (179), Expect = 4.427e-17
Identity = 45/127 (35.43%), Postives = 65/127 (51.18%), Query Frame = -1 
Query:    4 NVAKFVGED--IKKGVDLWFIQSSGFTFSD---------NSCSLPTCGHYTQLVWANSTEVGCGLSKCSIDGIDLNL----------LVCNYAPGGNYVAEKPYKPGTACSEC--ESGQDCSKYGLC 315
            N+A +VG +  +   V  WF +   + + +         ++C  P C HYTQLVWA S  VGC +  C    +D+++          LVCNY+P GN++ E PY+ GT CS C    G  C + GLC
Sbjct:   63 NLAVYVGSERPLAYHVQAWFDEEEWYQYPEEKECSPECPHTCRGPICTHYTQLVWAESRRVGCAVHTC----LDISVWDAVWPYALYLVCNYSPKGNWIGEAPYRQGTPCSRCPPRYGGSC-RGGLC 184
[Close]
BLAST of SMED30013976 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000002250.1 (pep scaffold:Pmarinus_7.0:GL477299:1626:22672:-1 gene:ENSPMAG00000002049.1 transcript:ENSPMAT00000002250.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 62.3882 bits (150), Expect = 9.336e-14
Identity = 31/69 (44.93%), Postives = 40/69 (57.97%), Query Frame = -1 
Query:   40 SCSLPTCGHYTQLVWANSTEVGCGLSKCSIDGIDLNL------LVCNYAPGGNYVAEKPYKPGTACSEC 228
             C+   C HYTQLVWA +  VGC ++ C    +   +      LVCNY+P GN++   PYK G ACSEC
Sbjct:   90 RCNGAVCTHYTQLVWATTNRVGCAINTCYNMNVWGQIWEKAVYLVCNYSPKGNWIGLSPYKSGRACSEC 158
[Close]
BLAST of SMED30013976 vs. Ensembl Sea Lamprey
Match: CRISP3 (cysteine rich secretory protein 3 [Source:HGNC Symbol;Acc:HGNC:16904])

HSP 1 Score: 57.3806 bits (137), Expect = 1.454e-11
Identity = 32/85 (37.65%), Postives = 47/85 (55.29%), Query Frame = -1 
Query:   40 GVDLWF--IQSSGFTFSDNSCSLPTCGHYTQLVWANSTEVGCGLSKCSID-GIDLNLLVCNYAPGGNYVAE--KPYKPGTACSEC 279
             +  W+  + S GF +   S +    GHYTQLVW NS ++GC ++ C  + G+   L VC+Y P GN      +PY  GT+C+ C
Sbjct:  118 AIRDWYNEVISPGFQYDVGSTTTGAVGHYTQLVWYNSFQLGCAVNYCPKNPGVAKYLYVCHYCPMGNLNTRINRPYDLGTSCASC 202
[Close]
BLAST of SMED30013976 vs. Ensembl Sea Lamprey
Match: CRISP2 (cysteine rich secretory protein 2 [Source:HGNC Symbol;Acc:HGNC:12024])

HSP 1 Score: 49.6766 bits (117), Expect = 4.383e-9
Identity = 33/99 (33.33%), Postives = 50/99 (50.51%), Query Frame = -1 
Query:    1 KKGVDLWFIQSS--GFTFSDNSCSLPTCGHYTQLVWANSTEVGCGLSKCSIDGIDLNLLVCNYAPGGNYVAE--KPYKPGTACSECESGQDCSKYGLCS 285
            +  V  W+ ++   GF F     +    GHYTQ+VW +S ++GC ++ C  + I   + VC+Y P GN      +PY  G+ C  C +  DC    LCS
Sbjct:   15 QDAVLDWYNEAEVPGFIFGKGPAAPGDIGHYTQVVWYSSFQLGCAVNYCP-EAIYKYVYVCHYCPAGNLNTRLSRPYNEGSPCRSCPN--DCEN-DLCS 109
[Close]
BLAST of SMED30013976 vs. Ensembl Sea Lamprey
Match: CRISP2 (cysteine rich secretory protein 2 [Source:HGNC Symbol;Acc:HGNC:12024])

HSP 1 Score: 48.521 bits (114), Expect = 1.867e-8
Identity = 30/92 (32.61%), Postives = 46/92 (50.00%), Query Frame = -1 
Query:   25 EDIKKGVDLWFIQSSGFTFSDNSCSLPTCGHYTQLVWANSTEVGCGLSKCSIDGIDLNLLVCNYAPGGNY--VAEKPYKPGTACSECESGQD 294
            E IK  VD     S GF +     +    GHYTQ++W ++ +VGC ++ C  +     + +C Y P GN+     KPY  G +C +C +  D
Sbjct:   62 EAIKVWVDE--ANSPGFDYGKGPRNPGIVGHYTQIIWYSTYQVGCTINYCPEEAYKY-MYLCAYCPVGNWNNRLTKPYDEGPSCQDCPNDCD 150
[Close]
BLAST of SMED30013976 vs. Ensembl Yeast
Match: PRY1 (Sterol binding protein involved in the export of acetylated sterols; secreted glycoprotein and member of the CAP protein superfamily (cysteine-rich secretory proteins (CRISP), antigen 5, and pathogenesis related 1 proteins); sterol export function is redundant with that of PRY2; may be involved in detoxification of hydrophobic compounds; PRY1 has a paralog, PRY2, that arose from the whole genome duplication [Source:SGD;Acc:S000003615])

HSP 1 Score: 56.225 bits (134), Expect = 2.785e-11
Identity = 30/75 (40.00%), Postives = 45/75 (60.00%), Query Frame = -1 
Query:   76 VGEDIKKGVDLWFIQSSGFTFSDNSCSLPTCGHYTQLVWANSTEVGCGLSKCSIDGIDLNLLVCNYAPGGNYVAE 300
            +G D    VD W+ + S + FS+   S  T GH+TQ+VW ++T+VGCG+  C   G   + ++C+Y P GNY  E
Sbjct:  219 LGYDGPAAVDAWYNEISNYDFSNPGFSSNT-GHFTQVVWKSTTQVGCGIKTCG--GAWGDYVICSYDPAGNYEGE 290
[Close]
BLAST of SMED30013976 vs. Ensembl Yeast
Match: PRY3 (Cell wall-associated protein involved in export of acetylated sterols; member of the CAP protein superfamily (cysteine-rich secretory proteins (CRISP), antigen 5, and pathogenesis related 1 proteins); role in mating efficiency; expression of full-length transcript is daughter cell-specific; in response to alpha factor, a short transcript starting at +452 is expressed and the long form is repressed by Ste12p [Source:SGD;Acc:S000003614])

HSP 1 Score: 50.447 bits (119), Expect = 4.284e-9
Identity = 31/81 (38.27%), Postives = 46/81 (56.79%), Query Frame = -1 
Query:   76 GEDIKKG------VDLWFIQSSGFTFSDNSCSLPTCGHYTQLVWANSTEVGCGLSKCSIDGIDL-NLLVCNYAPGGNYVAE 297
            GE++  G      VD W+ + S + +S+   S  T GH+TQ+VW ++ E+GCG   C   G    N +VC+Y P GNY+ E
Sbjct:   77 GENLALGYTDTGAVDAWYGEISKYNYSNPGFSEST-GHFTQVVWKSTAEIGCGYKYC---GTTWNNYIVCSYNPPGNYLGE 153
[Close]
BLAST of SMED30013976 vs. Ensembl Yeast
Match: PRY2 (Sterol binding protein involved in the export of acetylated sterols; secreted glycoprotein and member of the CAP protein superfamily (cysteine-rich secretory proteins (CRISP), antigen 5, and pathogenesis related 1 proteins); sterol export function is redundant with that of PRY1; may be involved in detoxification of hydrophobic compounds; PRY2 has a paralog, PRY1, that arose from the whole genome duplication [Source:SGD;Acc:S000001721])

HSP 1 Score: 48.521 bits (114), Expect = 1.552e-8
Identity = 24/67 (35.82%), Postives = 40/67 (59.70%), Query Frame = -1 
Query:   76 VDLWFIQSSGFTFSDNSCSLPTCGHYTQLVWANSTEVGCGLSKCSIDGIDLNLLVCNYAPGGNYVAE 276
            VD W+ + + + +S+   S  + GH+TQ+VW  ++EVGCGL  C  +  D   ++C+Y   GN + E
Sbjct:  257 VDAWYNEITSYDYSNPGFS-ESAGHFTQVVWKGTSEVGCGLKSCGGEWGD--YIICSYKAAGNVIGE 320
[Close]
BLAST of SMED30013976 vs. Ensembl Nematostella
Match: EDO38628 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SCA9])

HSP 1 Score: 55.4546 bits (132), Expect = 1.663e-10
Identity = 24/73 (32.88%), Postives = 41/73 (56.16%), Query Frame = -1 
Query:   67 KKGVDLWFIQSSGFTFSDNSCSLPTCGHYTQLVWANSTEVGCGLSKCSIDGIDLNLLVCNYAPGGNYVAEKPY 285
            +   DLW+ + + + ++  + S    GH+TQ+VW NS ++G G +K +  G+    +V  YAP GN V +  Y
Sbjct:  185 EDATDLWYAEIADYDWNYYNQSTGVIGHFTQVVWKNSLQLGVGAAKYTAGGLTKTYIVARYAPAGNVVGQANY 257
[Close]
BLAST of SMED30013976 vs. Ensembl Nematostella
Match: EDO48881 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RHM8])

HSP 1 Score: 50.447 bits (119), Expect = 3.471e-9
Identity = 24/72 (33.33%), Postives = 39/72 (54.17%), Query Frame = -1 
Query:   70 KKGVDLWFIQSSGFTFSDNSCSLPTCGHYTQLVWANSTEVGCGLSKCSIDGIDLNLLVCNYAPGGNYVAEKP 285
            +K  D+W+ +   + F +   S  + GH+TQ+VWA STE+G G +  S      + +V  Y P GN + + P
Sbjct:   68 RKATDMWYGEVDKYRFENPGFST-SSGHFTQVVWAGSTEMGAGKATSSSGA---HFVVARYTPPGNVMGQFP 135
[Close]
BLAST of SMED30013976 vs. Ensembl Nematostella
Match: EDO30082 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7T1T5])

HSP 1 Score: 49.2914 bits (116), Expect = 2.067e-8
Identity = 23/75 (30.67%), Postives = 41/75 (54.67%), Query Frame = -1 
Query:   67 KKGVDLWFIQSSGFTFSDNSCSLP--TCGHYTQLVWANSTEVGCGLSKCSIDGIDLNLLVCNYAPGGNYVAEKPY 285
            +  VD W+ +   + ++D + + P    GH+TQ+VW ++TEVG G++K  + G     +V  Y   GN + +  Y
Sbjct:  153 QDAVDSWYSEIDNYDYTDYT-NHPGGVIGHFTQIVWKSTTEVGVGVAKAIVGGWTKTYIVARYRTAGNAIGQSHY 226
[Close]
BLAST of SMED30013976 vs. Ensembl Nematostella
Match: EDO49310 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RH92])

HSP 1 Score: 48.521 bits (114), Expect = 5.260e-8
Identity = 27/68 (39.71%), Postives = 37/68 (54.41%), Query Frame = -1 
Query:   88 DIKKGVDLWFIQSSGFTFSDNSCSLPTCGHYTQLVWANSTEVGCGLSKCSIDGIDLNLLVCNYAPGGN 291
            DI   + +W+ +S  + + DN     T GH+TQ+VW  + EVG G +K S DG  L   V  Y P GN
Sbjct:  279 DIGDALQIWYNESESYQY-DNPGFALTTGHFTQIVWRGTREVGVGFAK-SPDG-RLTYAVARYNPPGN 343
[Close]
BLAST of SMED30013976 vs. Ensembl Nematostella
Match: EDO40545 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S6Z3])

HSP 1 Score: 47.3654 bits (111), Expect = 5.363e-8
Identity = 22/67 (32.84%), Postives = 40/67 (59.70%), Query Frame = -1 
Query:   85 KKGVDLWFIQSSGFTFSDNSCSLPTCGHYTQLVWANSTEVGCGLSKCSIDGIDLNLLVCNYAPGGNY 285
            K+ V  W+ +   + F++ + ++ T GH+TQ+VW +S E+G G +   ++GI    +V  Y P GN+
Sbjct:   79 KEAVTNWYNEVCKYDFNNGAFAMET-GHFTQVVWTDSIELGMGKATGKLNGIPCVFVVGRYRPPGNF 144
[Close]
BLAST of SMED30013976 vs. Ensembl Medaka
Match: ENSORLT00000023160.2 (peptidase inhibitor 16 [Source:NCBI gene;Acc:101164782])

HSP 1 Score: 87.4261 bits (215), Expect = 1.620e-21
Identity = 42/101 (41.58%), Postives = 60/101 (59.41%), Query Frame = -1 
Query:    4 DIKKGVDLWFIQSSGFTFSDNSCSL-PTCGHYTQLVWANSTEVGCGLSKC-SIDGIDLN---LLVCNYAPGGNYVAEKPYKPGTACSECESGQDCSKYGLC 291
            D+ + V+ WF++   +++ +NSC     CGHYTQ+VWA++  VGC +  C +I+ +D N    LVCNY P GNY  E+PY  G  CS C    D  +  LC
Sbjct:  126 DLSEAVEKWFLERLDYSYENNSCDEDKMCGHYTQMVWADTHRVGCAVHFCNTIENLDWNNVSYLVCNYFPAGNYDDERPYVEGDWCSRCPEDLDVCQNHLC 226
[Close]
BLAST of SMED30013976 vs. Ensembl Medaka
Match: crispld2 (cysteine rich secretory protein LCCL domain containing 2 [Source:NCBI gene;Acc:101174090])

HSP 1 Score: 68.1662 bits (165), Expect = 1.743e-14
Identity = 34/94 (36.17%), Postives = 46/94 (48.94%), Query Frame = -1 
Query:   40 VDLWFIQSSGFTFS---------DNSCSLPTCGHYTQLVWANSTEVGCGLSKCSIDGI------DLNLLVCNYAPGGNYVAEKPYKPGTACSEC 276
            V  W+ +   +T+             CS P C HYTQLVWA +  VGC +  C    +          LVCNY+P GN++ E PY+ G  CS+C
Sbjct:  148 VQAWYDEVKDYTYPYPSECNPWCPERCSGPMCTHYTQLVWATTNRVGCAVHVCPKMNVWGEIWETAVYLVCNYSPKGNWIGEAPYRHGRPCSQC 241
[Close]
BLAST of SMED30013976 vs. Ensembl Medaka
Match: crispld1a (cysteine rich secretory protein LCCL domain containing 1 [Source:NCBI gene;Acc:101172850])

HSP 1 Score: 67.781 bits (164), Expect = 2.478e-14
Identity = 32/68 (47.06%), Postives = 39/68 (57.35%), Query Frame = -1 
Query:   40 CSLPTCGHYTQLVWANSTEVGCGLSKCSIDGI------DLNLLVCNYAPGGNYVAEKPYKPGTACSEC 225
            CS P C HYTQLVWA S+ +GC ++ C    +          LVCNY+P GN+    PYK GT CS C
Sbjct:  187 CSGPVCTHYTQLVWATSSRIGCAINLCHNMDVWGQIWAKAVYLVCNYSPKGNWWGHAPYKHGTPCSAC 254
[Close]
BLAST of SMED30013976 vs. Ensembl Medaka
Match: pi15a (peptidase inhibitor 15 [Source:NCBI gene;Acc:101173911])

HSP 1 Score: 66.6254 bits (161), Expect = 2.987e-14
Identity = 38/117 (32.48%), Postives = 57/117 (48.72%), Query Frame = -1 
Query:   40 NVAKFVGED----------IKKGVDLWFIQSSGFTFS-----DNSCSL----PTCGHYTQLVWANSTEVGCGLSKCSIDGI------DLNLLVCNYAPGGNYVAEKPYKPGTACSEC 315
            ++ +F+G++          I + V  W+ +   ++F      +  C L    P C HYTQ+VWA S +VGC +  C    +          LVCNY+P GN++ E PYK G  CS C
Sbjct:  115 HLLRFLGQNLSVRTGRYRSILQLVKPWYDEVKDYSFPYPRDCNPRCPLRCYGPMCTHYTQMVWATSNKVGCAIHTCYNMNVWGSVWKRATYLVCNYSPKGNWIGEAPYKVGVPCSAC 231
[Close]
BLAST of SMED30013976 vs. Ensembl Medaka
Match: crispld1b (cysteine-rich secretory protein LCCL domain-containing 1 [Source:NCBI gene;Acc:101169145])

HSP 1 Score: 67.3958 bits (163), Expect = 3.891e-14
Identity = 33/72 (45.83%), Postives = 41/72 (56.94%), Query Frame = -1 
Query:   40 CSLPTCGHYTQLVWANSTEVGCGLSKCSIDGIDLNL----------LVCNYAPGGNYVAEKPYKPGTACSEC 225
            CS P C HYTQLVWA S  +GC ++ C     ++N+          LVCNY+P GN+    PYK GT CS C
Sbjct:  215 CSGPVCTHYTQLVWATSNRIGCAINVC----YNMNVWGMIWAKAVYLVCNYSPPGNWWGHAPYKYGTPCSAC 282
[Close]
BLAST of SMED30013976 vs. Planmine SMEST
Match: SMESG000003513.1 (SMESG000003513.1)

HSP 1 Score: 184.496 bits (467), Expect = 7.043e-62
Identity = 85/105 (80.95%), Postives = 96/105 (91.43%), Query Frame = -1 
Query:    1 NVAKFVGEDIKKGVDLWFIQSSGFTFSDNSCSLPTCGHYTQLVWANSTEVGCGLSKCSIDGIDLNLLVCNYAPGGNYVAEKPYKPGTACSECESGQDCSKYGLCS 315
            NVAKF G+ I +GV+LWF Q SGF+F +N+CSL TCGHYTQLVWANS E+GCG+++CSIDGI+LNLLVCNYAPGGNYV EKPYKPGTACSECESGQDCSKYGLCS
Sbjct:   19 NVAKFAGQKIARGVELWFNQVSGFSFENNTCSLKTCGHYTQLVWANSNELGCGMAECSIDGIELNLLVCNYAPGGNYVGEKPYKPGTACSECESGQDCSKYGLCS 123
[Close]
BLAST of SMED30013976 vs. Planmine SMEST
Match: SMESG000017377.1 (SMESG000017377.1)

HSP 1 Score: 176.792 bits (447), Expect = 9.629e-58
Identity = 85/105 (80.95%), Postives = 94/105 (89.52%), Query Frame = -1 
Query:    1 NVAKFVGEDIKKGVDLWFIQSSGFTFSDNSCSLPTCGHYTQLVWANSTEVGCGLSKCSIDGIDLNLLVCNYAPGGNYVAEKPYKPGTACSECESGQDCSKYGLCS 315
            NVAKF G+DI +GVDLW IQ  GFTF+DNSCSL TCGHYTQLVWANSTEVGCGLSKCSIDGIDL+LLVCNY PGGNYV+EKPYK G +CSEC+SGQ CS+ GLC+
Sbjct:   95 NVAKFAGQDIARGVDLWSIQVFGFTFADNSCSLKTCGHYTQLVWANSTEVGCGLSKCSIDGIDLSLLVCNYGPGGNYVSEKPYKLGKSCSECKSGQSCSQ-GLCN 198
[Close]
BLAST of SMED30013976 vs. Planmine SMEST
Match: SMESG000000510.1 (SMESG000000510.1)

HSP 1 Score: 172.17 bits (435), Expect = 7.531e-56
Identity = 81/104 (77.88%), Postives = 88/104 (84.62%), Query Frame = -1 
Query:    4 NVAKFVGEDIKKGVDLWFIQSSGFTFSDNSCSLPTCGHYTQLVWANSTEVGCGLSKCSIDGIDLNLLVCNYAPGGNYVAEKPYKPGTACSECESGQDCSKYGLC 315
            NV KF G D+ +GV LW+ Q SGFTFS+NSCSL TCGHYTQLVWANSTEVGCGL++C IDGIDLNLLVCNY PGGNYV EKPYK G  CSEC+SGQ CS YGLC
Sbjct:   95 NVVKFAGIDVGRGVFLWYNQVSGFTFSNNSCSLKTCGHYTQLVWANSTEVGCGLAECVIDGIDLNLLVCNYGPGGNYVGEKPYKSGEPCSECKSGQSCSAYGLC 198
[Close]
BLAST of SMED30013976 vs. Planmine SMEST
Match: SMESG000000320.1 (SMESG000000320.1)

HSP 1 Score: 169.859 bits (429), Expect = 5.717e-55
Identity = 79/104 (75.96%), Postives = 87/104 (83.65%), Query Frame = -1 
Query:    4 NVAKFVGEDIKKGVDLWFIQSSGFTFSDNSCSLPTCGHYTQLVWANSTEVGCGLSKCSIDGIDLNLLVCNYAPGGNYVAEKPYKPGTACSECESGQDCSKYGLC 315
            NVAKF GE I +G +LW IQ SGFTF  ++CSL TCGHYTQLVWANSTE+GCGL+KC IDGIDLNLLVCNY PGGNYV EKPYK G  CSEC+SGQ C+ YGLC
Sbjct:  101 NVAKFAGERIYRGAELWNIQVSGFTFESSACSLKTCGHYTQLVWANSTELGCGLAKCIIDGIDLNLLVCNYGPGGNYVGEKPYKSGEPCSECKSGQSCTAYGLC 204
[Close]
BLAST of SMED30013976 vs. Planmine SMEST
Match: SMESG000000320.1 (SMESG000000320.1)

HSP 1 Score: 170.244 bits (430), Expect = 8.027e-55
Identity = 79/104 (75.96%), Postives = 87/104 (83.65%), Query Frame = -1 
Query:    4 NVAKFVGEDIKKGVDLWFIQSSGFTFSDNSCSLPTCGHYTQLVWANSTEVGCGLSKCSIDGIDLNLLVCNYAPGGNYVAEKPYKPGTACSECESGQDCSKYGLC 315
            NVAKF GE I +G +LW IQ SGFTF  ++CSL TCGHYTQLVWANSTE+GCGL+KC IDGIDLNLLVCNY PGGNYV EKPYK G  CSEC+SGQ C+ YGLC
Sbjct:  124 NVAKFAGERIYRGAELWNIQVSGFTFESSACSLKTCGHYTQLVWANSTELGCGLAKCIIDGIDLNLLVCNYGPGGNYVGEKPYKSGEPCSECKSGQSCTAYGLC 227
The following BLAST results are available for this feature:
BLAST of SMED30013976 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5
Match NameE-valueIdentityDescription
PI161.143e-1939.81peptidase inhibitor 16 [Source:HGNC Symbol;Acc:HGN... [more]
PI161.143e-1939.81peptidase inhibitor 16 [Source:HGNC Symbol;Acc:HGN... [more]
PI161.143e-1939.81peptidase inhibitor 16 [Source:HGNC Symbol;Acc:HGN... [more]
GLIPR1L12.476e-1837.96GLIPR1 like 1 [Source:HGNC Symbol;Acc:HGNC:28392][more]
GLIPR1L12.822e-1837.96GLIPR1 like 1 [Source:HGNC Symbol;Acc:HGNC:28392][more]
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BLAST of SMED30013976 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 5
Match NameE-valueIdentityDescription
scl-106.743e-1547.14SCP-Like extracellular protein [Source:UniProtKB/... [more]
scl-146.806e-1434.74SCP-Like extracellular protein [Source:UniProtKB/... [more]
scl-59.416e-1436.00SCP-Like extracellular protein [Source:UniProtKB/... [more]
scl-115.000e-1341.67SCP-Like extracellular protein [Source:UniProtKB/... [more]
scl-28.473e-1343.66SCP-Like extracellular protein [Source:UniProtKB/... [more]
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BLAST of SMED30013976 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 4
Match NameE-valueIdentityDescription
CG84834.758e-1335.71gene:FBgn0038126 transcript:FBtr0082782[more]
CG42701.394e-1036.92gene:FBgn0031407 transcript:FBtr0077754[more]
CG326793.760e-930.69gene:FBgn0052679 transcript:FBtr0071469[more]
CG42702.135e-634.88gene:FBgn0031407 transcript:FBtr0077755[more]
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BLAST of SMED30013976 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
r3hdml9.638e-1743.16R3H domain containing-like [Source:ZFIN;Acc:ZDB-GE... [more]
r3hdml9.638e-1743.16R3H domain containing-like [Source:ZFIN;Acc:ZDB-GE... [more]
CU914487.11.805e-1639.58peptidase inhibitor 16-like [Source:NCBI gene;Acc:... [more]
glipr1a1.114e-1535.35GLI pathogenesis-related 1a [Source:ZFIN;Acc:ZDB-G... [more]
glipr1a2.261e-1535.35GLI pathogenesis-related 1a [Source:ZFIN;Acc:ZDB-G... [more]
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BLAST of SMED30013976 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5
Match NameE-valueIdentityDescription
ENSXETT00000036788.13.423e-2242.72pep primary_assembly:Xenopus_tropicalis_v9.1:KV464... [more]
crispld21.955e-1538.30cysteine-rich secretory protein LCCL domain contai... [more]
crispld22.424e-1538.30cysteine-rich secretory protein LCCL domain contai... [more]
crispld22.732e-1538.30cysteine-rich secretory protein LCCL domain contai... [more]
CRISPLD11.480e-1344.44cysteine-rich secretory protein LCCL domain contai... [more]
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BLAST of SMED30013976 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Glipr1l11.980e-2040.54GLI pathogenesis-related 1 like 1 [Source:MGI Symb... [more]
Pi161.671e-1838.83peptidase inhibitor 16 [Source:MGI Symbol;Acc:MGI:... [more]
Pi165.388e-1838.78peptidase inhibitor 16 [Source:MGI Symbol;Acc:MGI:... [more]
Pi167.691e-1838.78peptidase inhibitor 16 [Source:MGI Symbol;Acc:MGI:... [more]
Pi167.691e-1838.78peptidase inhibitor 16 [Source:MGI Symbol;Acc:MGI:... [more]
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BLAST of SMED30013976 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|Q9DAG6|GPRL1_MOUSE1.385e-1940.54GLIPR1-like protein 1 OS=Mus musculus OX=10090 GN=... [more]
sp|Q6UXB8|PI16_HUMAN5.488e-1939.81Peptidase inhibitor 16 OS=Homo sapiens OX=9606 GN=... [more]
sp|Q58D34|PI16_BOVIN2.138e-1838.83Peptidase inhibitor 16 OS=Bos taurus OX=9913 GN=PI... [more]
sp|Q32LB5|GPRL1_BOVIN4.757e-1846.43GLIPR1-like protein 1 OS=Bos taurus OX=9913 GN=GLI... [more]
sp|Q9ET66|PI16_MOUSE1.169e-1738.83Peptidase inhibitor 16 OS=Mus musculus OX=10090 GN... [more]
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BLAST of SMED30013976 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
C3ZIM91.266e-2144.92SCP domain-containing protein (Fragment) OS=Branch... [more]
C3ZIM71.294e-2144.92SCP domain-containing protein (Fragment) OS=Branch... [more]
T2MBL61.337e-2147.42Peptidase inhibitor 16 (Fragment) OS=Hydra vulgari... [more]
C3Z2D91.386e-2144.92SCP domain-containing protein (Fragment) OS=Branch... [more]
A0A3P6I5322.080e-2144.44SCP domain-containing protein OS=Mesocestoides cor... [more]
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BLAST of SMED30013976 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
ENSAMXT00000036030.11.960e-2143.82peptidase inhibitor 16 [Source:NCBI gene;Acc:10302... [more]
ENSAMXT00000031557.12.488e-2143.82peptidase inhibitor 16 [Source:NCBI gene;Acc:10302... [more]
ENSAMXT00000029824.14.109e-2143.82peptidase inhibitor 16 [Source:NCBI gene;Acc:10302... [more]
r3hdml7.522e-1734.75R3H domain containing like [Source:NCBI gene;Acc:1... [more]
crispld22.225e-1547.06cysteine-rich secretory protein LCCL domain contai... [more]
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BLAST of SMED30013976 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 5
Match NameE-valueIdentityDescription
ENSPMAT00000000374.14.427e-1735.43pep scaffold:Pmarinus_7.0:GL476650:75849:87118:-1 ... [more]
ENSPMAT00000002250.19.336e-1444.93pep scaffold:Pmarinus_7.0:GL477299:1626:22672:-1 g... [more]
CRISP31.454e-1137.65cysteine rich secretory protein 3 [Source:HGNC Sym... [more]
CRISP24.383e-933.33cysteine rich secretory protein 2 [Source:HGNC Sym... [more]
CRISP21.867e-832.61cysteine rich secretory protein 2 [Source:HGNC Sym... [more]
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BLAST of SMED30013976 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 3
Match NameE-valueIdentityDescription
PRY12.785e-1140.00Sterol binding protein involved in the export of a... [more]
PRY34.284e-938.27Cell wall-associated protein involved in export of... [more]
PRY21.552e-835.82Sterol binding protein involved in the export of a... [more]
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BLAST of SMED30013976 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 5
Match NameE-valueIdentityDescription
EDO386281.663e-1032.88Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO488813.471e-933.33Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO300822.067e-830.67Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO493105.260e-839.71Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO405455.363e-832.84Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
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BLAST of SMED30013976 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5
Match NameE-valueIdentityDescription
ENSORLT00000023160.21.620e-2141.58peptidase inhibitor 16 [Source:NCBI gene;Acc:10116... [more]
crispld21.743e-1436.17cysteine rich secretory protein LCCL domain contai... [more]
crispld1a2.478e-1447.06cysteine rich secretory protein LCCL domain contai... [more]
pi15a2.987e-1432.48peptidase inhibitor 15 [Source:NCBI gene;Acc:10117... [more]
crispld1b3.891e-1445.83cysteine-rich secretory protein LCCL domain-contai... [more]
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BLAST of SMED30013976 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5
Match NameE-valueIdentityDescription
SMESG000003513.17.043e-6280.95SMESG000003513.1[more]
SMESG000017377.19.629e-5880.95SMESG000017377.1[more]
SMESG000000510.17.531e-5677.88SMESG000000510.1[more]
SMESG000000320.15.717e-5575.96SMESG000000320.1[more]
SMESG000000320.18.027e-5575.96SMESG000000320.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30013976 ID=SMED30013976|Name=SMED30013976|organism=Schmidtea mediterranea sexual|type=transcript|length=315bp
ACTACAAAGTCCATATTTACTGCAGTCTTGGCCGGATTCGCATTCAGAAC
ATGCCGTGCCAGGTTTATAGGGTTTCTCAGCGACATAATTGCCTCCGGGA
GCGTAATTGCAAACTAACAAATTCAAATCAATTCCGTCAATTGAACATTT
GGAAAGTCCACATCCAACCTCAGTAGAGTTGGCCCATACAAGTTGTGTAT
AATGGCCGCAGGTTGGTAATGAACAGGAATTATCTGAAAATGTGAATCCG
GAAGACTGAATAAACCACAAATCTACGCCTTTTTTAATATCTTCTCCAAC
GAACTTAGCAACATT
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protein sequence of SMED30013976-orf-1

>SMED30013976-orf-1 ID=SMED30013976-orf-1|Name=SMED30013976-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=105bp
NVAKFVGEDIKKGVDLWFIQSSGFTFSDNSCSLPTCGHYTQLVWANSTEV
GCGLSKCSIDGIDLNLLVCNYAPGGNYVAEKPYKPGTACSECESGQDCSK
YGLCS
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000016pharynx
PLANA:0000025nervous system
PLANA:0000026gut
PLANA:0000070intestinal phagocyte
PLANA:0000099neuron
PLANA:0000421tail
Vocabulary: INTERPRO
TermDefinition
IPR035940CAP_sf
IPR001283CRISP-related
IPR014044CAP_domain
IPR018244Allrgn_V5/Tpx1_CS
Vocabulary: cellular component
TermDefinition
GO:0005576extracellular region
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR001283Cysteine-rich secretory protein-relatedPRINTSPR00837V5TPXLIKEcoord: 51..64
score: 53.16
coord: 21..37
score: 60.56
IPR001283Cysteine-rich secretory protein-relatedPANTHERPTHR10334CYSTEINE-RICH SECRETORY PROTEIN-RELATEDcoord: 2..84
IPR014044CAP domainSMARTSM00198SCP_3coord: 1..64
e-value: 0.0039
score: -29.4
IPR014044CAP domainPFAMPF00188CAPcoord: 2..56
e-value: 2.8E-9
score: 37.9
IPR035940CAP superfamilyGENE3DG3DSA:3.40.33.10coord: 1..90
e-value: 6.1E-31
score: 109.5
IPR035940CAP superfamilySUPERFAMILYSSF55797PR-1-likecoord: 1..71
NoneNo IPR availablePANTHERPTHR10334:SF414coord: 2..84
NoneNo IPR availableCDDcd05381CAP_PR-1coord: 1..68
e-value: 9.44926E-22
score: 80.3705
IPR018244Allergen V5/Tpx-1-related, conserved sitePROSITEPS01010CRISP_2coord: 51..62
IPR018244Allergen V5/Tpx-1-related, conserved sitePROSITEPS01009CRISP_1coord: 22..32