Adenylate kinase

Overview
NameAdenylate kinase
Smed IDSMED30013913
Length (bp)884
Neoblast Clusters

Zeng et. al., 2018




▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 



 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)




Explore this single cell expression dataset with our NB Cluster Shiny App




 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of Adenylate kinase (SMED30013913) t-SNE clustered cells

Violin plots show distribution of expression levels for Adenylate kinase (SMED30013913) in cells (dots) of each of the 12 neoblast clusters.

 

back to top


 

Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of Adenylate kinase (SMED30013913) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for Adenylate kinase (SMED30013913) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

back to top


 

Embryonic Expression

Davies et. al., 2017




Hover the mouse over a column in the graph to view average RPKM values per sample.
Sort Descending | Sort Ascending | Only Non-Zero Values | Tile/Chart | Reset

Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

back to top
Anatomical Expression

PAGE et. al., 2020




SMED30013913

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 8

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
gutSMED30013913h1SMcG0002286 Contig2730newmark_estsPMID:23079596
Forsthoefel et al., 2012
whole organism asexual adult colorimetric in situ hybridization evidence
gutSMED30013913h1SMcG0002286 Contig2730uc_Smed_v2PMID:23079596
Forsthoefel et al., 2012
whole organism asexual adult colorimetric in situ hybridization evidence
intestinal phagocyteSMED30013913h1SMcG0002286 Contig2730newmark_estsPMID:23079596
Forsthoefel et al., 2012
FACS sorted cell population asexual adult cDNA to DNA expression microarray evidence
intestinal phagocyteSMED30013913h1SMcG0002286 Contig2730uc_Smed_v2PMID:23079596
Forsthoefel et al., 2012
FACS sorted cell population asexual adult cDNA to DNA expression microarray evidence
gutSMED30013913h1SMcG0016044 Contig2730newmark_estsPMID:23079596
Forsthoefel et al., 2012
whole organism asexual adult colorimetric in situ hybridization evidence
gutSMED30013913h1SMcG0016044 Contig2730uc_Smed_v2PMID:23079596
Forsthoefel et al., 2012
whole organism asexual adult colorimetric in situ hybridization evidence
intestinal phagocyteSMED30013913h1SMcG0016044 Contig2730newmark_estsPMID:23079596
Forsthoefel et al., 2012
FACS sorted cell population asexual adult cDNA to DNA expression microarray evidence
intestinal phagocyteSMED30013913h1SMcG0016044 Contig2730uc_Smed_v2PMID:23079596
Forsthoefel et al., 2012
FACS sorted cell population asexual adult cDNA to DNA expression microarray evidence
Note: Hover over icons to view figure legend
Homology
BLAST of Adenylate kinase vs. Ensembl Human
Match: AK2 (adenylate kinase 2 [Source:HGNC Symbol;Acc:HGNC:362])

HSP 1 Score: 294.278 bits (752), Expect = 5.023e-100
Identity = 136/220 (61.82%), Postives = 169/220 (76.82%), Query Frame = 1
Query:  127 ESKQNINAILIGPAGSGKGTQAPKLVERYKICHLATGDMLRAIVSSGSPLGRQVNEIMQQGGLISDEIVCKLIEENLSKQECKNGFILDGFPRTVGQAEKLDQLLEKRNSKINAVVEFNVDDSVLERRITGRLFHLSSGRSYHEEFNPPKQPMIDDITGEKLVRRKDDNVETLKSRLQSYRTDTAPLIGYYQKRNVHYQVKASQKPDRVFEDILNFFEKS 786
            E  + I A+L+GP G+GKGTQAP+L E + +CHLATGDMLRA+V+SGS LG+++   M  G L+SDE+V +LIE+NL    CKNGF+LDGFPRTV QAE LD L+EKR  K+++V+EF++ DS+L RRITGRL H  SGRSYHEEFNPPK+PM DDITGE L+RR DDN + LK RLQ+Y T T PLI YY+KR +H  + ASQ PD VF  IL  F K+
Sbjct:   11 EYPKGIRAVLLGPPGAGKGTQAPRLAENFCVCHLATGDMLRAMVASGSELGKKLKATMDAGKLVSDEMVVELIEKNLETPLCKNGFLLDGFPRTVRQAEMLDDLMEKRKEKLDSVIEFSIPDSLLIRRITGRLIHPKSGRSYHEEFNPPKEPMKDDITGEPLIRRSDDNEKALKIRLQAYHTQTTPLIEYYRKRGIHSAIDASQTPDVVFASILAAFSKA 230          
BLAST of Adenylate kinase vs. Ensembl Human
Match: AK2 (adenylate kinase 2 [Source:HGNC Symbol;Acc:HGNC:362])

HSP 1 Score: 293.893 bits (751), Expect = 5.982e-100
Identity = 136/220 (61.82%), Postives = 169/220 (76.82%), Query Frame = 1
Query:  127 ESKQNINAILIGPAGSGKGTQAPKLVERYKICHLATGDMLRAIVSSGSPLGRQVNEIMQQGGLISDEIVCKLIEENLSKQECKNGFILDGFPRTVGQAEKLDQLLEKRNSKINAVVEFNVDDSVLERRITGRLFHLSSGRSYHEEFNPPKQPMIDDITGEKLVRRKDDNVETLKSRLQSYRTDTAPLIGYYQKRNVHYQVKASQKPDRVFEDILNFFEKS 786
            E  + I A+L+GP G+GKGTQAP+L E + +CHLATGDMLRA+V+SGS LG+++   M  G L+SDE+V +LIE+NL    CKNGF+LDGFPRTV QAE LD L+EKR  K+++V+EF++ DS+L RRITGRL H  SGRSYHEEFNPPK+PM DDITGE L+RR DDN + LK RLQ+Y T T PLI YY+KR +H  + ASQ PD VF  IL  F K+
Sbjct:   11 EYPKGIRAVLLGPPGAGKGTQAPRLAENFCVCHLATGDMLRAMVASGSELGKKLKATMDAGKLVSDEMVVELIEKNLETPLCKNGFLLDGFPRTVRQAEMLDDLMEKRKEKLDSVIEFSIPDSLLIRRITGRLIHPKSGRSYHEEFNPPKEPMKDDITGEPLIRRSDDNEKALKIRLQAYHTQTTPLIEYYRKRGIHSAIDASQTPDVVFASILAAFSKA 230          
BLAST of Adenylate kinase vs. Ensembl Human
Match: AK2 (adenylate kinase 2 [Source:HGNC Symbol;Acc:HGNC:362])

HSP 1 Score: 293.893 bits (751), Expect = 7.593e-100
Identity = 136/220 (61.82%), Postives = 169/220 (76.82%), Query Frame = 1
Query:  127 ESKQNINAILIGPAGSGKGTQAPKLVERYKICHLATGDMLRAIVSSGSPLGRQVNEIMQQGGLISDEIVCKLIEENLSKQECKNGFILDGFPRTVGQAEKLDQLLEKRNSKINAVVEFNVDDSVLERRITGRLFHLSSGRSYHEEFNPPKQPMIDDITGEKLVRRKDDNVETLKSRLQSYRTDTAPLIGYYQKRNVHYQVKASQKPDRVFEDILNFFEKS 786
            E  + I A+L+GP G+GKGTQAP+L E + +CHLATGDMLRA+V+SGS LG+++   M  G L+SDE+V +LIE+NL    CKNGF+LDGFPRTV QAE LD L+EKR  K+++V+EF++ DS+L RRITGRL H  SGRSYHEEFNPPK+PM DDITGE L+RR DDN + LK RLQ+Y T T PLI YY+KR +H  + ASQ PD VF  IL  F K+
Sbjct:   11 EYPKGIRAVLLGPPGAGKGTQAPRLAENFCVCHLATGDMLRAMVASGSELGKKLKATMDAGKLVSDEMVVELIEKNLETPLCKNGFLLDGFPRTVRQAEMLDDLMEKRKEKLDSVIEFSIPDSLLIRRITGRLIHPKSGRSYHEEFNPPKEPMKDDITGEPLIRRSDDNEKALKIRLQAYHTQTTPLIEYYRKRGIHSAIDASQTPDVVFASILAAFSKA 230          
BLAST of Adenylate kinase vs. Ensembl Human
Match: AK2 (adenylate kinase 2 [Source:HGNC Symbol;Acc:HGNC:362])

HSP 1 Score: 220.32 bits (560), Expect = 1.330e-71
Identity = 112/220 (50.91%), Postives = 137/220 (62.27%), Query Frame = 1
Query:  127 ESKQNINAILIGPAGSGKGTQAPKLVERYKICHLATGDMLRAIVSSGSPLGRQVNEIMQQGGLISDEIVCKLIEENLSKQECKNGFILDGFPRTVGQAEKLDQLLEKRNSKINAVVEFNVDDSVLERRITGRLFHLSSGRSYHEEFNPPKQPMIDDITGEKLVRRKDDNVETLKSRLQSYRTDTAPLIGYYQKRNVHYQVKASQKPDRVFEDILNFFEKS 786
            E  + I A+L+GP G+GKGTQ                                          +SDE+V +LIE+NL    CKNGF+LDGFPRTV QAE LD L+EKR  K+++V+EF++ DS+L RRITGRL H  SGRSYHEEFNPPK+PM DDITGE L+RR DDN + LK RLQ+Y T T PLI YY+KR +H  + ASQ PD VF  IL  F K+
Sbjct:   11 EYPKGIRAVLLGPPGAGKGTQ------------------------------------------VSDEMVVELIEKNLETPLCKNGFLLDGFPRTVRQAEMLDDLMEKRKEKLDSVIEFSIPDSLLIRRITGRLIHPKSGRSYHEEFNPPKEPMKDDITGEPLIRRSDDNEKALKIRLQAYHTQTTPLIEYYRKRGIHSAIDASQTPDVVFASILAAFSKA 188          
BLAST of Adenylate kinase vs. Ensembl Human
Match: AK2 (adenylate kinase 2 [Source:HGNC Symbol;Acc:HGNC:362])

HSP 1 Score: 219.935 bits (559), Expect = 2.394e-71
Identity = 112/220 (50.91%), Postives = 137/220 (62.27%), Query Frame = 1
Query:  127 ESKQNINAILIGPAGSGKGTQAPKLVERYKICHLATGDMLRAIVSSGSPLGRQVNEIMQQGGLISDEIVCKLIEENLSKQECKNGFILDGFPRTVGQAEKLDQLLEKRNSKINAVVEFNVDDSVLERRITGRLFHLSSGRSYHEEFNPPKQPMIDDITGEKLVRRKDDNVETLKSRLQSYRTDTAPLIGYYQKRNVHYQVKASQKPDRVFEDILNFFEKS 786
            E  + I A+L+GP G+GKGTQ                                          +SDE+V +LIE+NL    CKNGF+LDGFPRTV QAE LD L+EKR  K+++V+EF++ DS+L RRITGRL H  SGRSYHEEFNPPK+PM DDITGE L+RR DDN + LK RLQ+Y T T PLI YY+KR +H  + ASQ PD VF  IL  F K+
Sbjct:   11 EYPKGIRAVLLGPPGAGKGTQ------------------------------------------VSDEMVVELIEKNLETPLCKNGFLLDGFPRTVRQAEMLDDLMEKRKEKLDSVIEFSIPDSLLIRRITGRLIHPKSGRSYHEEFNPPKEPMKDDITGEPLIRRSDDNEKALKIRLQAYHTQTTPLIEYYRKRGIHSAIDASQTPDVVFASILAAFSKA 188          
BLAST of Adenylate kinase vs. Ensembl Celegans
Match: let-754 (Adenylate kinase [Source:UniProtKB/Swiss-Prot;Acc:P34346])

HSP 1 Score: 270.781 bits (691), Expect = 5.634e-91
Identity = 128/216 (59.26%), Postives = 156/216 (72.22%), Query Frame = 1
Query:  136 QNINAILIGPAGSGKGTQAPKLVERYKICHLATGDMLRAIVSSGSPLGRQVNEIMQQGGLISDEIVCKLIEENLSKQECKNGFILDGFPRTVGQAEKLDQLLEKRNSKINAVVEFNVDDSVLERRITGRLFHLSSGRSYHEEFNPPKQPMIDDITGEKLVRRKDDNVETLKSRLQSYRTDTAPLIGYYQKRNVHYQVKASQKPDRVFEDILNFFEK 783
            + I AI IGP GSGKGTQAP   ++Y  CHLATGD+LRA V+SGS  G+++   M  G L+SDE+VCKLIE+ L K ECK GFILDGFPRT GQAEKLD++LE+R + ++ VVEFN+ D +L RRITGRLFH++SGRSYH EF PPK PM DD+TGE L+RR DDN ETL+ RL  Y   T PL+ YY+K  VH  V A++    V   I   F K
Sbjct:   25 RGIRAIFIGPPGSGKGTQAPAFAQKYFSCHLATGDLLRAEVASGSEFGKELKATMDAGKLVSDEVVCKLIEQKLEKPECKYGFILDGFPRTSGQAEKLDEILERRKTPLDTVVEFNIADDLLVRRITGRLFHIASGRSYHLEFKPPKVPMKDDLTGEPLIRRSDDNEETLRKRLVQYHQMTVPLVDYYKKHGVHVAVDAAKPMTDVKAHIDQVFAK 240          
BLAST of Adenylate kinase vs. Ensembl Celegans
Match: let-754 (Adenylate kinase [Source:UniProtKB/Swiss-Prot;Acc:P34346])

HSP 1 Score: 270.781 bits (691), Expect = 5.634e-91
Identity = 128/216 (59.26%), Postives = 156/216 (72.22%), Query Frame = 1
Query:  136 QNINAILIGPAGSGKGTQAPKLVERYKICHLATGDMLRAIVSSGSPLGRQVNEIMQQGGLISDEIVCKLIEENLSKQECKNGFILDGFPRTVGQAEKLDQLLEKRNSKINAVVEFNVDDSVLERRITGRLFHLSSGRSYHEEFNPPKQPMIDDITGEKLVRRKDDNVETLKSRLQSYRTDTAPLIGYYQKRNVHYQVKASQKPDRVFEDILNFFEK 783
            + I AI IGP GSGKGTQAP   ++Y  CHLATGD+LRA V+SGS  G+++   M  G L+SDE+VCKLIE+ L K ECK GFILDGFPRT GQAEKLD++LE+R + ++ VVEFN+ D +L RRITGRLFH++SGRSYH EF PPK PM DD+TGE L+RR DDN ETL+ RL  Y   T PL+ YY+K  VH  V A++    V   I   F K
Sbjct:   25 RGIRAIFIGPPGSGKGTQAPAFAQKYFSCHLATGDLLRAEVASGSEFGKELKATMDAGKLVSDEVVCKLIEQKLEKPECKYGFILDGFPRTSGQAEKLDEILERRKTPLDTVVEFNIADDLLVRRITGRLFHIASGRSYHLEFKPPKVPMKDDLTGEPLIRRSDDNEETLRKRLVQYHQMTVPLVDYYKKHGVHVAVDAAKPMTDVKAHIDQVFAK 240          
BLAST of Adenylate kinase vs. Ensembl Celegans
Match: F38B2.4 (Adenylate kinase isoenzyme 1 [Source:UniProtKB/Swiss-Prot;Acc:Q20140])

HSP 1 Score: 118.242 bits (295), Expect = 4.950e-32
Identity = 69/213 (32.39%), Postives = 117/213 (54.93%), Query Frame = 1
Query:  154 LIGPAGSGKGTQAPKLVERYKICHLATGDMLRAIVSSGSPLGRQVNEIMQQGGLISDEIVCKLIEENLSK--QECKNGFILDGFPRTVGQAEKLDQLLEKRNSKINAVVEFNVDDSVLERRITGRLFHLSSGRSYHEEFNPPKQPMIDDITGEKLVRRKDDNVETLKSRLQSYRTDTAPLIGYYQKRNVHYQVKASQKPDRVFEDILNFFEKS 786
            ++G  GSGKGTQ  K+V +Y + HL++GD+LR  V SGSP G Q+  IM+ G L+  E+V  L++E + K  ++   GF++DG+PR V Q ++ +   E + +K+  V+ F+V +  L +R+  R    +SGR+                         DDN +T+K RL ++ T TAP++ YY+ +    ++ A    D +F  ++   +K+
Sbjct:   25 IVGGPGSGKGTQCDKIVAKYGLTHLSSGDLLRDEVKSGSPRGAQLTAIMESGALVPLEVVLDLVKEAMLKAIEKGSKGFLIDGYPREVAQGQQFES--EIQEAKL--VLFFDVAEETLVKRLLHR--AQTSGRA-------------------------DDNADTIKKRLHTFVTSTAPVVDYYESKGKLVRINAEGSVDDIFAVVVANLDKA 206          
BLAST of Adenylate kinase vs. Ensembl Celegans
Match: ZK673.2 (Probable adenylate kinase isoenzyme ZK673.2 [Source:UniProtKB/Swiss-Prot;Acc:Q09629])

HSP 1 Score: 109.768 bits (273), Expect = 1.172e-28
Identity = 64/190 (33.68%), Postives = 104/190 (54.74%), Query Frame = 1
Query:  151 ILIGPAGSGKGTQAPKLVERYK---ICHLATGDMLRAIVSSGSPLGRQVNEIMQQGGLISDEIVCKLIEENLSKQECKNGFILDGFPRTVGQAEKLDQLLEKRNSKINAVVEFNVDDSVLERRITGRLFHLSSGRSYHEEFNPPKQPMIDDITGEKLVRRKDDNVETLKSRLQSYRTDTAPLIGYYQKRN 711
            +L G AGSGKGT A  LV  ++     + A GD +R  ++ G+  G +    + +G  + D I+   I   + K   +   +LDG+PR + Q + +++      + +N +VE  V   VL  R++ +L H +SGR+Y+ E NPPK+   DDITGE L +R  D +E  + RL+ Y      ++ YY+K+N
Sbjct:    5 LLSGAAGSGKGTIARMLVREFEPLGFNYFAAGDFIRDHIARGTEFGVRAQSFLNKGEHVPDSILNGAILAEMLKAGPR--VVLDGYPRNMSQLKMVEE-----QAPLNLIVELKVPRKVLIDRLSKQLVHPASGRAYNLEVNPPKEEGKDDITGEPLFKRSTDQLEVARRRLEVYDKTENKVLDYYKKQN 187          
BLAST of Adenylate kinase vs. Ensembl Celegans
Match: C29F7.3 (UMP-CMP kinase 1 [Source:UniProtKB/Swiss-Prot;Acc:O17622])

HSP 1 Score: 90.5077 bits (223), Expect = 9.176e-22
Identity = 60/217 (27.65%), Postives = 100/217 (46.08%), Query Frame = 1
Query:  148 AILIGPAGSGKGTQAPKLVERYKICHLATGDMLRAIVS-SGSPLGRQVNEIMQQGGLISDEIVCKLIEENLSKQECKNGFILDGFPRTVGQAEKLD-QLLEKRNSKINAVVEFNVDDSVLERRITGRLFHLSSGRSYHEEFNPPKQPMIDDITGEKLVRRKDDNVETLKSRLQSYRTDTAPLIGYYQKRNVHYQVKASQKPDRVFEDILNFFEKSRK 792
              ++GP GSGKGT   ++ E     HL+ GD+LRA    +GS  G  +   ++ G ++  EI C L+E  +   +  NGF++DGFPR        + Q+  K N +    +   VD  +       R  H   GR+                         DDNVE+LK R+++Y   T P+I +++K  +  +V + +    V+ED++  F  + +
Sbjct:    5 VFVLGPPGSGKGTICTQIHENLGYVHLSAGDLLRAERERAGSEYGALIEGHIKNGSIVPVEITCALLENAMIASKDANGFLIDGFPRNEDNWSGWNKQMGGKVNEQFVLFLSCPVDVCI------DRCLHRGQGRT-------------------------DDNVESLKKRVETYNQSTFPIIEHFEKVGMVREVNSERPVTEVYEDVVKVFAAANQ 190          
BLAST of Adenylate kinase vs. Ensembl Fly
Match: Adk2 (gene:FBgn0283494 transcript:FBtr0072163)

HSP 1 Score: 285.804 bits (730), Expect = 7.762e-97
Identity = 130/216 (60.19%), Postives = 168/216 (77.78%), Query Frame = 1
Query:  142 INAILIGPAGSGKGTQAPKLVERYKICHLATGDMLRAIVSSGSPLGRQVNEIMQQGGLISDEIVCKLIEENLSKQECKNGFILDGFPRTVGQAEKLDQLLEKRNSKINAVVEFNVDDSVLERRITGRLFHLSSGRSYHEEFNPPKQPMIDDITGEKLVRRKDDNVETLKSRLQSYRTDTAPLIGYYQKRNVHYQVKASQKPDRVFEDILNFFEKSR 789
            INAIL+GP GSGKGTQAP L E++ +CHL+TGDMLRA +SSGS LG ++ ++M  G L+SD++V  +I+ NL K ECKNGF+LDGFPRTV QAEKLD LL+KR + ++AV+EF +DDS+L RRITGRL H +SGRSYHEEF PPK+PM DD+TGE L+RR DDN E LK RL++Y   T PL+ YY  R +H++V A++K   VF  I + F++ R
Sbjct:   19 INAILLGPPGSGKGTQAPLLKEKFCVCHLSTGDMLRAEISSGSKLGAELKKVMDAGKLVSDDLVVDMIDSNLDKPECKNGFLLDGFPRTVVQAEKLDTLLDKRKTNLDAVIEFAIDDSLLVRRITGRLIHQASGRSYHEEFAPPKKPMTDDVTGEPLIRRSDDNAEALKKRLEAYHKQTKPLVDYYGLRGLHFKVDAAKKSSDVFSTIDSIFQRKR 234          
BLAST of Adenylate kinase vs. Ensembl Fly
Match: Adk3 (gene:FBgn0042094 transcript:FBtr0082331)

HSP 1 Score: 129.798 bits (325), Expect = 2.889e-36
Identity = 71/198 (35.86%), Postives = 112/198 (56.57%), Query Frame = 1
Query:  148 AILIGPAGSGKGTQAPKLVERYKICHLATGDMLRAIVSSGSPLGRQVNEIMQQGGLISDEIVCKLIEENLSKQECKN-GFILDGFPRTVGQAEKLDQLLEKRNSKINAVVEFNVDDSVLERRITGRLFHLSSGRSYHEEFNPPKQPMIDDITGEKLVRRKDDNVETLKSRLQSYRTDTAPLIGYYQKRNVHYQVKASQ 738
            A++IG  GSGKGT +  + + +   H++TGD+LR  +   + LG++  + + +G L+ D IV K +   ++  E  N  +ILDGFPR + QAE L         +I+AV+  +V  SV+  R+  R  H  SGR Y+  F  PK P  DD+TGE L++R+DD    +  RL+ Y    +P+I +Y+K+ +    K  Q
Sbjct:    8 AVIIGAPGSGKGTISELICKNHGCVHISTGDILRQNIIKNTELGKKAKQYIAEGKLVPDAIVTKTMLARIT--EVGNRSYILDGFPRNIAQAEAL-----AAREQIDAVITLDVPHSVIIDRVKNRWIHAPSGRVYNIGFKNPKVPGKDDVTGEPLMQREDDKPHVVAKRLELYDEVMSPVIAWYEKKGLVATFKGKQ 198          
BLAST of Adenylate kinase vs. Ensembl Fly
Match: Adk3 (gene:FBgn0042094 transcript:FBtr0339379)

HSP 1 Score: 129.798 bits (325), Expect = 2.889e-36
Identity = 71/198 (35.86%), Postives = 112/198 (56.57%), Query Frame = 1
Query:  148 AILIGPAGSGKGTQAPKLVERYKICHLATGDMLRAIVSSGSPLGRQVNEIMQQGGLISDEIVCKLIEENLSKQECKN-GFILDGFPRTVGQAEKLDQLLEKRNSKINAVVEFNVDDSVLERRITGRLFHLSSGRSYHEEFNPPKQPMIDDITGEKLVRRKDDNVETLKSRLQSYRTDTAPLIGYYQKRNVHYQVKASQ 738
            A++IG  GSGKGT +  + + +   H++TGD+LR  +   + LG++  + + +G L+ D IV K +   ++  E  N  +ILDGFPR + QAE L         +I+AV+  +V  SV+  R+  R  H  SGR Y+  F  PK P  DD+TGE L++R+DD    +  RL+ Y    +P+I +Y+K+ +    K  Q
Sbjct:    8 AVIIGAPGSGKGTISELICKNHGCVHISTGDILRQNIIKNTELGKKAKQYIAEGKLVPDAIVTKTMLARIT--EVGNRSYILDGFPRNIAQAEAL-----AAREQIDAVITLDVPHSVIIDRVKNRWIHAPSGRVYNIGFKNPKVPGKDDVTGEPLMQREDDKPHVVAKRLELYDEVMSPVIAWYEKKGLVATFKGKQ 198          
BLAST of Adenylate kinase vs. Ensembl Fly
Match: Adk3 (gene:FBgn0042094 transcript:FBtr0082330)

HSP 1 Score: 129.798 bits (325), Expect = 2.889e-36
Identity = 71/198 (35.86%), Postives = 112/198 (56.57%), Query Frame = 1
Query:  148 AILIGPAGSGKGTQAPKLVERYKICHLATGDMLRAIVSSGSPLGRQVNEIMQQGGLISDEIVCKLIEENLSKQECKN-GFILDGFPRTVGQAEKLDQLLEKRNSKINAVVEFNVDDSVLERRITGRLFHLSSGRSYHEEFNPPKQPMIDDITGEKLVRRKDDNVETLKSRLQSYRTDTAPLIGYYQKRNVHYQVKASQ 738
            A++IG  GSGKGT +  + + +   H++TGD+LR  +   + LG++  + + +G L+ D IV K +   ++  E  N  +ILDGFPR + QAE L         +I+AV+  +V  SV+  R+  R  H  SGR Y+  F  PK P  DD+TGE L++R+DD    +  RL+ Y    +P+I +Y+K+ +    K  Q
Sbjct:    8 AVIIGAPGSGKGTISELICKNHGCVHISTGDILRQNIIKNTELGKKAKQYIAEGKLVPDAIVTKTMLARIT--EVGNRSYILDGFPRNIAQAEAL-----AAREQIDAVITLDVPHSVIIDRVKNRWIHAPSGRVYNIGFKNPKVPGKDDVTGEPLMQREDDKPHVVAKRLELYDEVMSPVIAWYEKKGLVATFKGKQ 198          
BLAST of Adenylate kinase vs. Ensembl Fly
Match: Adk3 (gene:FBgn0042094 transcript:FBtr0339378)

HSP 1 Score: 129.798 bits (325), Expect = 2.889e-36
Identity = 71/198 (35.86%), Postives = 112/198 (56.57%), Query Frame = 1
Query:  148 AILIGPAGSGKGTQAPKLVERYKICHLATGDMLRAIVSSGSPLGRQVNEIMQQGGLISDEIVCKLIEENLSKQECKN-GFILDGFPRTVGQAEKLDQLLEKRNSKINAVVEFNVDDSVLERRITGRLFHLSSGRSYHEEFNPPKQPMIDDITGEKLVRRKDDNVETLKSRLQSYRTDTAPLIGYYQKRNVHYQVKASQ 738
            A++IG  GSGKGT +  + + +   H++TGD+LR  +   + LG++  + + +G L+ D IV K +   ++  E  N  +ILDGFPR + QAE L         +I+AV+  +V  SV+  R+  R  H  SGR Y+  F  PK P  DD+TGE L++R+DD    +  RL+ Y    +P+I +Y+K+ +    K  Q
Sbjct:    8 AVIIGAPGSGKGTISELICKNHGCVHISTGDILRQNIIKNTELGKKAKQYIAEGKLVPDAIVTKTMLARIT--EVGNRSYILDGFPRNIAQAEAL-----AAREQIDAVITLDVPHSVIIDRVKNRWIHAPSGRVYNIGFKNPKVPGKDDVTGEPLMQREDDKPHVVAKRLELYDEVMSPVIAWYEKKGLVATFKGKQ 198          
BLAST of Adenylate kinase vs. Ensembl Zebrafish
Match: ak2 (adenylate kinase 2 [Source:NCBI gene;Acc:321793])

HSP 1 Score: 288.5 bits (737), Expect = 7.380e-98
Identity = 134/222 (60.36%), Postives = 169/222 (76.13%), Query Frame = 1
Query:  121 VSESKQNINAILIGPAGSGKGTQAPKLVERYKICHLATGDMLRAIVSSGSPLGRQVNEIMQQGGLISDEIVCKLIEENLSKQECKNGFILDGFPRTVGQAEKLDQLLEKRNSKINAVVEFNVDDSVLERRITGRLFHLSSGRSYHEEFNPPKQPMIDDITGEKLVRRKDDNVETLKSRLQSYRTDTAPLIGYYQKRNVHYQVKASQKPDRVFEDILNFFEKS 786
            VS  ++ I AIL+GP G+GKGTQAPKL E+Y +CHLATGDMLRA+V+SGS LG+++ E M  G L+SDE+V +LI+ NL    CKNGF+LDGFPRTV QAE LD L+EKR+ K+++V+EF+VDDS+L RRI GRL H  SGRSYHEEF+PPK+ M DD+TGE L+RR DDN  TL+SRL+SY   T+PL+ YY  R +H  + ASQ  D VF  IL  F  +
Sbjct:   11 VSGIRKGIRAILLGPPGAGKGTQAPKLAEKYCVCHLATGDMLRAMVASGSELGQRLKETMDAGKLVSDEMVVELIDNNLDTPACKNGFLLDGFPRTVKQAEMLDDLMEKRSEKLDSVIEFSVDDSLLVRRICGRLIHQPSGRSYHEEFHPPKEHMKDDVTGEPLIRRSDDNETTLRSRLESYHRQTSPLVQYYSARGLHTAIDASQSTDLVFASILAAFSAA 232          
BLAST of Adenylate kinase vs. Ensembl Zebrafish
Match: ak2 (adenylate kinase 2 [Source:NCBI gene;Acc:321793])

HSP 1 Score: 288.115 bits (736), Expect = 1.297e-97
Identity = 134/222 (60.36%), Postives = 169/222 (76.13%), Query Frame = 1
Query:  121 VSESKQNINAILIGPAGSGKGTQAPKLVERYKICHLATGDMLRAIVSSGSPLGRQVNEIMQQGGLISDEIVCKLIEENLSKQECKNGFILDGFPRTVGQAEKLDQLLEKRNSKINAVVEFNVDDSVLERRITGRLFHLSSGRSYHEEFNPPKQPMIDDITGEKLVRRKDDNVETLKSRLQSYRTDTAPLIGYYQKRNVHYQVKASQKPDRVFEDILNFFEKS 786
            VS  ++ I AIL+GP G+GKGTQAPKL E+Y +CHLATGDMLRA+V+SGS LG+++ E M  G L+SDE+V +LI+ NL    CKNGF+LDGFPRTV QAE LD L+EKR+ K+++V+EF+VDDS+L RRI GRL H  SGRSYHEEF+PPK+ M DD+TGE L+RR DDN  TL+SRL+SY   T+PL+ YY  R +H  + ASQ  D VF  IL  F  +
Sbjct:   11 VSGIRKGIRAILLGPPGAGKGTQAPKLAEKYCVCHLATGDMLRAMVASGSELGQRLKETMDAGKLVSDEMVVELIDNNLDTPACKNGFLLDGFPRTVKQAEMLDDLMEKRSEKLDSVIEFSVDDSLLVRRICGRLIHQPSGRSYHEEFHPPKEHMKDDVTGEPLIRRSDDNETTLRSRLESYHRQTSPLVQYYSARGLHTAIDASQSTDLVFASILAAFSAA 232          
BLAST of Adenylate kinase vs. Ensembl Zebrafish
Match: ak3 (adenylate kinase 3 [Source:ZFIN;Acc:ZDB-GENE-040426-2142])

HSP 1 Score: 160.229 bits (404), Expect = 7.575e-48
Identity = 78/212 (36.79%), Postives = 133/212 (62.74%), Query Frame = 1
Query:  148 AILIGPAGSGKGTQAPKLVERYKICHLATGDMLRAIVSSGSPLGRQVNEIMQQGGLISDEIVCKLIEENLSKQECKNGFILDGFPRTVGQAEKLDQLLEKRNSKINAVVEFNVDDSVLERRITGRLFHLSSGRSYHEEFNPPKQPMIDDITGEKLVRRKDDNVETLKSRLQSYRTDTAPLIGYYQKRNVHYQVKASQKPDRVFEDILNFFEK 783
            A+++G  GSGKGT + ++ + + + HL++GDMLRA + + + LG  +   + QG L+ D+++ +LI  +L   E K  ++LDGFPRTV QAE LD + +     +++V+  +V    +  R+T R  HL SGR Y+ +FNPPK+P +DD+TGE LV+R DD+ ET+  RL+ Y   T P++ YY+ + V  +  +  + ++++  +  F  +
Sbjct:    9 AVIMGAPGSGKGTVSSRIAQSFGLKHLSSGDMLRANIEAKTDLGLLMKSCIDQGQLVPDDVISRLILSSLRGLE-KTSWLLDGFPRTVAQAEALDCVYD-----VDSVINLDVPFQTIRERLTSRWVHLPSGRVYNIDFNPPKKPGLDDVTGEPLVQRDDDSPETVSRRLKDYERQTQPVLEYYRSKGV-LETFSGTETNKIWPHVHTFLSR 213          
BLAST of Adenylate kinase vs. Ensembl Zebrafish
Match: ak4 (adenylate kinase 4 [Source:ZFIN;Acc:ZDB-GENE-040426-2505])

HSP 1 Score: 135.576 bits (340), Expect = 3.054e-38
Identity = 68/206 (33.01%), Postives = 121/206 (58.74%), Query Frame = 1
Query:  148 AILIGPAGSGKGTQAPKLVERYKICHLATGDMLRAIVSSGSPLGRQVNEIMQQGGLISDEIVCKLIEENLSKQECKNGFILDGFPRTVGQAEKLDQLLEKRNSKINAVVEFNVDDSVLERRITGRLFHLSSGRSYHEEFNPPKQPMIDDITGEKLVRRKDDNVETLKSRLQSYRTDTAPLIGYYQKRNVHYQVKASQKPDRVFEDI 765
            A+++GP GSGKGT + ++   + + HL++GD +R  +SS +  G      + +G L+ D ++ +L+   L ++  K  ++LDGFPRT+ QAE L+      +  ++  +  N+    L+ R+  R  H  SGR Y+  FNPP+   +DDITGE L++++DD  E L +RL+ Y+    P+I +Y+ + + Y    ++  DR++ +I
Sbjct:    7 AVIMGPPGSGKGTISERIAHNFGLKHLSSGDFVRENISSKTDAGVLAKTYINKGLLVPDHVMTRLLLPRL-EEMTKYSWLLDGFPRTLAQAEALNS-----SCDLDVAINLNIPLETLKERLRHRWIHPPSGRVYNMCFNPPRIQGLDDITGEALIQQEDDRPEALVARLRHYKDVAKPVIDFYKAKGILYTFSDTET-DRIWPNI 205          
BLAST of Adenylate kinase vs. Ensembl Zebrafish
Match: ak4 (adenylate kinase 4 [Source:ZFIN;Acc:ZDB-GENE-040426-2505])

HSP 1 Score: 135.576 bits (340), Expect = 3.054e-38
Identity = 68/206 (33.01%), Postives = 121/206 (58.74%), Query Frame = 1
Query:  148 AILIGPAGSGKGTQAPKLVERYKICHLATGDMLRAIVSSGSPLGRQVNEIMQQGGLISDEIVCKLIEENLSKQECKNGFILDGFPRTVGQAEKLDQLLEKRNSKINAVVEFNVDDSVLERRITGRLFHLSSGRSYHEEFNPPKQPMIDDITGEKLVRRKDDNVETLKSRLQSYRTDTAPLIGYYQKRNVHYQVKASQKPDRVFEDI 765
            A+++GP GSGKGT + ++   + + HL++GD +R  +SS +  G      + +G L+ D ++ +L+   L ++  K  ++LDGFPRT+ QAE L+      +  ++  +  N+    L+ R+  R  H  SGR Y+  FNPP+   +DDITGE L++++DD  E L +RL+ Y+    P+I +Y+ + + Y    ++  DR++ +I
Sbjct:    7 AVIMGPPGSGKGTISERIAHNFGLKHLSSGDFVRENISSKTDAGVLAKTYINKGLLVPDHVMTRLLLPRL-EEMTKYSWLLDGFPRTLAQAEALNS-----SCDLDVAINLNIPLETLKERLRHRWIHPPSGRVYNMCFNPPRIQGLDDITGEALIQQEDDRPEALVARLRHYKDVAKPVIDFYKAKGILYTFSDTET-DRIWPNI 205          
BLAST of Adenylate kinase vs. Ensembl Xenopus
Match: ak2 (adenylate kinase 2 [Source:NCBI gene;Acc:448011])

HSP 1 Score: 298.516 bits (763), Expect = 8.864e-102
Identity = 138/218 (63.30%), Postives = 169/218 (77.52%), Query Frame = 1
Query:  136 QNINAILIGPAGSGKGTQAPKLVERYKICHLATGDMLRAIVSSGSPLGRQVNEIMQQGGLISDEIVCKLIEENLSKQECKNGFILDGFPRTVGQAEKLDQLLEKRNSKINAVVEFNVDDSVLERRITGRLFHLSSGRSYHEEFNPPKQPMIDDITGEKLVRRKDDNVETLKSRLQSYRTDTAPLIGYYQKRNVHYQVKASQKPDRVFEDILNFFEKSR 789
            + I AIL+GP G+GKGTQAPKL E+Y +CHLATGDMLRA+V+SGS LG ++   M  G L+SDE+V +LIE+NL    CK GF+LDGFPRTV QAE LD+LLEKR  K+++V+EF VDDS+L RRI GRL H SSGRSYHEEFNPPK+ M DD+TGE L+RR DDN  TLKSRL++Y T T+PL+ YYQ+  +H  V A+Q PD VF  IL  F K+R
Sbjct:   16 EGIRAILLGPPGAGKGTQAPKLAEKYCVCHLATGDMLRAMVASGSELGMRLKATMDAGKLVSDEMVVELIEKNLDTPPCKKGFLLDGFPRTVKQAEMLDELLEKRQEKLDSVIEFKVDDSLLVRRICGRLIHASSGRSYHEEFNPPKEAMKDDVTGEPLMRRSDDNETTLKSRLEAYHTMTSPLVEYYQRHGIHTAVDAAQSPDVVFASILAAFSKAR 233          
BLAST of Adenylate kinase vs. Ensembl Xenopus
Match: ak2 (adenylate kinase 2 [Source:NCBI gene;Acc:448011])

HSP 1 Score: 298.516 bits (763), Expect = 8.961e-102
Identity = 138/218 (63.30%), Postives = 169/218 (77.52%), Query Frame = 1
Query:  136 QNINAILIGPAGSGKGTQAPKLVERYKICHLATGDMLRAIVSSGSPLGRQVNEIMQQGGLISDEIVCKLIEENLSKQECKNGFILDGFPRTVGQAEKLDQLLEKRNSKINAVVEFNVDDSVLERRITGRLFHLSSGRSYHEEFNPPKQPMIDDITGEKLVRRKDDNVETLKSRLQSYRTDTAPLIGYYQKRNVHYQVKASQKPDRVFEDILNFFEKSR 789
            + I AIL+GP G+GKGTQAPKL E+Y +CHLATGDMLRA+V+SGS LG ++   M  G L+SDE+V +LIE+NL    CK GF+LDGFPRTV QAE LD+LLEKR  K+++V+EF VDDS+L RRI GRL H SSGRSYHEEFNPPK+ M DD+TGE L+RR DDN  TLKSRL++Y T T+PL+ YYQ+  +H  V A+Q PD VF  IL  F K+R
Sbjct:   16 EGIRAILLGPPGAGKGTQAPKLAEKYCVCHLATGDMLRAMVASGSELGMRLKATMDAGKLVSDEMVVELIEKNLDTPPCKKGFLLDGFPRTVKQAEMLDELLEKRQEKLDSVIEFKVDDSLLVRRICGRLIHASSGRSYHEEFNPPKEAMKDDVTGEPLMRRSDDNETTLKSRLEAYHTMTSPLVEYYQRHGIHTAVDAAQSPDVVFASILAAFSKAR 233          
BLAST of Adenylate kinase vs. Ensembl Xenopus
Match: ak2 (adenylate kinase 2 [Source:NCBI gene;Acc:448011])

HSP 1 Score: 296.975 bits (759), Expect = 4.663e-101
Identity = 137/217 (63.13%), Postives = 168/217 (77.42%), Query Frame = 1
Query:  136 QNINAILIGPAGSGKGTQAPKLVERYKICHLATGDMLRAIVSSGSPLGRQVNEIMQQGGLISDEIVCKLIEENLSKQECKNGFILDGFPRTVGQAEKLDQLLEKRNSKINAVVEFNVDDSVLERRITGRLFHLSSGRSYHEEFNPPKQPMIDDITGEKLVRRKDDNVETLKSRLQSYRTDTAPLIGYYQKRNVHYQVKASQKPDRVFEDILNFFEKS 786
            + I AIL+GP G+GKGTQAPKL E+Y +CHLATGDMLRA+V+SGS LG ++   M  G L+SDE+V +LIE+NL    CK GF+LDGFPRTV QAE LD+LLEKR  K+++V+EF VDDS+L RRI GRL H SSGRSYHEEFNPPK+ M DD+TGE L+RR DDN  TLKSRL++Y T T+PL+ YYQ+  +H  V A+Q PD VF  IL  F K+
Sbjct:   16 EGIRAILLGPPGAGKGTQAPKLAEKYCVCHLATGDMLRAMVASGSELGMRLKATMDAGKLVSDEMVVELIEKNLDTPPCKKGFLLDGFPRTVKQAEMLDELLEKRQEKLDSVIEFKVDDSLLVRRICGRLIHASSGRSYHEEFNPPKEAMKDDVTGEPLMRRSDDNETTLKSRLEAYHTMTSPLVEYYQRHGIHTAVDAAQSPDVVFASILAAFSKA 232          
BLAST of Adenylate kinase vs. Ensembl Xenopus
Match: ak3 (adenylate kinase 3 [Source:NCBI gene;Acc:100170447])

HSP 1 Score: 162.925 bits (411), Expect = 8.166e-49
Identity = 80/211 (37.91%), Postives = 132/211 (62.56%), Query Frame = 1
Query:  148 AILIGPAGSGKGTQAPKLVERYKICHLATGDMLRAIVSSGSPLGRQVNEIMQQGGLISDEIVCKLIEENLSKQECKNGFILDGFPRTVGQAEKLDQLLEKRNSKINAVVEFNVDDSVLERRITGRLFHLSSGRSYHEEFNPPKQPMIDDITGEKLVRRKDDNVETLKSRLQSYRTDTAPLIGYYQKRNVHYQVKASQKPDRVFEDILNFFE 780
            A+++GP GSGKGT + ++V+ + + HL++GD+LR  V + + +G      + QG L+ D+++ +L+ + L K    N ++LDGFPRTV QA  LD+        IN+V++ NV    ++ R+T R  H +SGR Y+ EFNPPK P +DD+TGE LV+R+DD  ET+  RL+ Y   T P++ YYQ + V  +  +  + ++++  +  F +
Sbjct:    9 AVIMGPPGSGKGTVSDRIVKNFALKHLSSGDLLRTNVQNKTEIGVVAKSYIDQGQLVPDDVITRLVLQELHKINETN-WLLDGFPRTVPQAVALDKAFH-----INSVIDLNVPFQTIKDRLTARWIHPASGRVYNTEFNPPKVPEVDDLTGEPLVQREDDKPETVTRRLKGYEALTRPVLEYYQNKGV-LETFSGTETNKIWPHVYAFLQ 212          
BLAST of Adenylate kinase vs. Ensembl Xenopus
Match: ak3 (adenylate kinase 3 [Source:NCBI gene;Acc:100170447])

HSP 1 Score: 162.155 bits (409), Expect = 1.097e-48
Identity = 79/188 (42.02%), Postives = 122/188 (64.89%), Query Frame = 1
Query:  148 AILIGPAGSGKGTQAPKLVERYKICHLATGDMLRAIVSSGSPLGRQVNEIMQQGGLISDEIVCKLIEENLSKQECKNGFILDGFPRTVGQAEKLDQLLEKRNSKINAVVEFNVDDSVLERRITGRLFHLSSGRSYHEEFNPPKQPMIDDITGEKLVRRKDDNVETLKSRLQSYRTDTAPLIGYYQKRN 711
            A+++GP GSGKGT + ++V+ + + HL++GD+LR  V + + +G      + QG L+ D+++ +L+ + L K    N ++LDGFPRTV QA  LD+        IN+V++ NV    ++ R+T R  H +SGR Y+ EFNPPK P +DD+TGE LV+R+DD  ET+  RL+ Y   T P++ YYQ R+
Sbjct:    9 AVIMGPPGSGKGTVSDRIVKNFALKHLSSGDLLRTNVQNKTEIGVVAKSYIDQGQLVPDDVITRLVLQELHKINETN-WLLDGFPRTVPQAVALDKAFH-----INSVIDLNVPFQTIKDRLTARWIHPASGRVYNTEFNPPKVPEVDDLTGEPLVQREDDKPETVTRRLKGYEALTRPVLEYYQGRH 190          
BLAST of Adenylate kinase vs. Ensembl Mouse
Match: Ak2 (adenylate kinase 2 [Source:MGI Symbol;Acc:MGI:87978])

HSP 1 Score: 295.819 bits (756), Expect = 8.067e-101
Identity = 137/227 (60.35%), Postives = 173/227 (76.21%), Query Frame = 1
Query:  112 NFFVSESK--QNINAILIGPAGSGKGTQAPKLVERYKICHLATGDMLRAIVSSGSPLGRQVNEIMQQGGLISDEIVCKLIEENLSKQECKNGFILDGFPRTVGQAEKLDQLLEKRNSKINAVVEFNVDDSVLERRITGRLFHLSSGRSYHEEFNPPKQPMIDDITGEKLVRRKDDNVETLKSRLQSYRTDTAPLIGYYQKRNVHYQVKASQKPDRVFEDILNFFEKS 786
            N   SE +  + I A+L+GP G+GKGTQAPKL E + +CHLATGDMLRA+V+SGS LG+++   M  G L+SDE+V +LIE+NL    CKNGF+LDGFPRTV QAE LD L+EKR  K+++V+EF++ DS+L RRITGRL H  SGRSYHEEFNPPK+PM DDITGE L+RR DDN + LK+RL++Y T T PL+ YY+KR +H  + ASQ PD VF  IL  F K+
Sbjct:    4 NVLASEPEIPKGIRAVLLGPPGAGKGTQAPKLAENFCVCHLATGDMLRAMVASGSELGKKLKATMDAGKLVSDEMVVELIEKNLETPSCKNGFLLDGFPRTVRQAEMLDDLMEKRKEKLDSVIEFSIQDSLLIRRITGRLIHPKSGRSYHEEFNPPKEPMKDDITGEPLIRRSDDNEKALKTRLEAYHTQTTPLVEYYRKRGIHCAIDASQTPDIVFASILAAFSKA 230          
BLAST of Adenylate kinase vs. Ensembl Mouse
Match: Ak2 (adenylate kinase 2 [Source:MGI Symbol;Acc:MGI:87978])

HSP 1 Score: 295.819 bits (756), Expect = 1.193e-100
Identity = 137/227 (60.35%), Postives = 173/227 (76.21%), Query Frame = 1
Query:  112 NFFVSESK--QNINAILIGPAGSGKGTQAPKLVERYKICHLATGDMLRAIVSSGSPLGRQVNEIMQQGGLISDEIVCKLIEENLSKQECKNGFILDGFPRTVGQAEKLDQLLEKRNSKINAVVEFNVDDSVLERRITGRLFHLSSGRSYHEEFNPPKQPMIDDITGEKLVRRKDDNVETLKSRLQSYRTDTAPLIGYYQKRNVHYQVKASQKPDRVFEDILNFFEKS 786
            N   SE +  + I A+L+GP G+GKGTQAPKL E + +CHLATGDMLRA+V+SGS LG+++   M  G L+SDE+V +LIE+NL    CKNGF+LDGFPRTV QAE LD L+EKR  K+++V+EF++ DS+L RRITGRL H  SGRSYHEEFNPPK+PM DDITGE L+RR DDN + LK+RL++Y T T PL+ YY+KR +H  + ASQ PD VF  IL  F K+
Sbjct:    4 NVLASEPEIPKGIRAVLLGPPGAGKGTQAPKLAENFCVCHLATGDMLRAMVASGSELGKKLKATMDAGKLVSDEMVVELIEKNLETPSCKNGFLLDGFPRTVRQAEMLDDLMEKRKEKLDSVIEFSIQDSLLIRRITGRLIHPKSGRSYHEEFNPPKEPMKDDITGEPLIRRSDDNEKALKTRLEAYHTQTTPLVEYYRKRGIHCAIDASQTPDIVFASILAAFSKA 230          
BLAST of Adenylate kinase vs. Ensembl Mouse
Match: Ak3 (adenylate kinase 3 [Source:MGI Symbol;Acc:MGI:1860835])

HSP 1 Score: 158.303 bits (399), Expect = 4.737e-47
Identity = 78/213 (36.62%), Postives = 135/213 (63.38%), Query Frame = 1
Query:  142 INAILIGPAGSGKGTQAPKLVERYKICHLATGDMLRAIVSSGSPLGRQVNEIMQQGGLISDEIVCKLIEENLSKQECKNGFILDGFPRTVGQAEKLDQLLEKRNSKINAVVEFNVDDSVLERRITGRLFHLSSGRSYHEEFNPPKQPMIDDITGEKLVRRKDDNVETLKSRLQSYRTDTAPLIGYYQKRNVHYQVKASQKPDRVFEDILNFFE 780
            + A+++G  GSGKGT + ++ + +++ HL++GD+LR  +  G+ +G      + QG LI D+++ +L    L K   +  ++LDGFPRT+ QAE LD++ +     I+ V+  NV   V+++R+T R  H +SGR Y+ EFNPPK   IDD+TGE L++R+DD  ET+  RL++Y   T P++ YYQK+ V  +  +  + ++++  + +F +
Sbjct:    8 LRAVIMGAPGSGKGTVSSRITKHFELKHLSSGDLLRQNMLQGTEIGVLAKTFIDQGKLIPDDVMTRLALHEL-KTLTQCSWLLDGFPRTLPQAEALDKVYQ-----IDTVINLNVPFEVIKQRLTARWIHPASGRVYNIEFNPPKTVGIDDLTGEPLIQREDDKPETVIKRLKAYEAQTEPVLQYYQKKGV-LETFSGTETNKIWPHVYSFLQ 213          
BLAST of Adenylate kinase vs. Ensembl Mouse
Match: Ak4 (adenylate kinase 4 [Source:MGI Symbol;Acc:MGI:87979])

HSP 1 Score: 145.976 bits (367), Expect = 2.937e-42
Identity = 71/212 (33.49%), Postives = 130/212 (61.32%), Query Frame = 1
Query:  142 INAILIGPAGSGKGTQAPKLVERYKICHLATGDMLRAIVSSGSPLGRQVNEIMQQGGLISDEIVCKLIEENLSKQECKNGFILDGFPRTVGQAEKLDQLLEKRNSKINAVVEFNVDDSVLERRITGRLFHLSSGRSYHEEFNPPKQPMIDDITGEKLVRRKDDNVETLKSRLQSYRTDTAPLIGYYQKRNVHYQVKASQKPDRVFEDILNFF 777
            + A+++GP GSGKGT   ++ + + + HL++G +LR  + +G+ +G    + +++G L+ D ++ +L+   L  +  ++ ++LDGFPRT+ QAE LD + +     ++ V+  N+    L+ R++ R  H SSGR Y+ +FNPP+   IDDITGE LV+++DD  E + +RL+ Y+    P+I  Y+ R V +Q   ++  +R++  +   F
Sbjct:    6 LRAVILGPPGSGKGTVCERIAQNFGLQHLSSGHLLRENLKTGTEVGDVAKQYLEKGLLVPDHVITRLMMSELETRSAQH-WLLDGFPRTLVQAEALDGICD-----VDLVISLNIPFETLKDRLSRRWIHPSSGRVYNLDFNPPQVQGIDDITGEPLVQQEDDKPEAVAARLRRYKDAAKPVIELYKSRGVLHQFSGTET-NRIWPYVYTLF 210          
BLAST of Adenylate kinase vs. Ensembl Mouse
Match: Ak4 (adenylate kinase 4 [Source:MGI Symbol;Acc:MGI:87979])

HSP 1 Score: 145.976 bits (367), Expect = 2.937e-42
Identity = 71/212 (33.49%), Postives = 130/212 (61.32%), Query Frame = 1
Query:  142 INAILIGPAGSGKGTQAPKLVERYKICHLATGDMLRAIVSSGSPLGRQVNEIMQQGGLISDEIVCKLIEENLSKQECKNGFILDGFPRTVGQAEKLDQLLEKRNSKINAVVEFNVDDSVLERRITGRLFHLSSGRSYHEEFNPPKQPMIDDITGEKLVRRKDDNVETLKSRLQSYRTDTAPLIGYYQKRNVHYQVKASQKPDRVFEDILNFF 777
            + A+++GP GSGKGT   ++ + + + HL++G +LR  + +G+ +G    + +++G L+ D ++ +L+   L  +  ++ ++LDGFPRT+ QAE LD + +     ++ V+  N+    L+ R++ R  H SSGR Y+ +FNPP+   IDDITGE LV+++DD  E + +RL+ Y+    P+I  Y+ R V +Q   ++  +R++  +   F
Sbjct:    6 LRAVILGPPGSGKGTVCERIAQNFGLQHLSSGHLLRENLKTGTEVGDVAKQYLEKGLLVPDHVITRLMMSELETRSAQH-WLLDGFPRTLVQAEALDGICD-----VDLVISLNIPFETLKDRLSRRWIHPSSGRVYNLDFNPPQVQGIDDITGEPLVQQEDDKPEAVAARLRRYKDAAKPVIELYKSRGVLHQFSGTET-NRIWPYVYTLF 210          
BLAST of Adenylate kinase vs. UniProt/SwissProt
Match: sp|Q8AVD3|KAD2_XENLA (Adenylate kinase 2, mitochondrial OS=Xenopus laevis OX=8355 GN=ak2 PE=2 SV=1)

HSP 1 Score: 301.982 bits (772), Expect = 2.591e-102
Identity = 138/217 (63.59%), Postives = 170/217 (78.34%), Query Frame = 1
Query:  136 QNINAILIGPAGSGKGTQAPKLVERYKICHLATGDMLRAIVSSGSPLGRQVNEIMQQGGLISDEIVCKLIEENLSKQECKNGFILDGFPRTVGQAEKLDQLLEKRNSKINAVVEFNVDDSVLERRITGRLFHLSSGRSYHEEFNPPKQPMIDDITGEKLVRRKDDNVETLKSRLQSYRTDTAPLIGYYQKRNVHYQVKASQKPDRVFEDILNFFEKS 786
            + I AIL+GP G+GKGTQAPKL E+Y +CHLATGDMLRA+V+SGS LG+++   M  G L+SDE+V +LIE+NL    CK GF+LDGFPRTV QAE LD+LLEKR  K+++V+EF VDDS+L RRI GRL H SSGRSYHEEFNPPK+PM DD+TGE L+RR DDN  TLKSRL++Y T T+PL+ YYQ+  +H  V A+Q PD VF  IL  F K+
Sbjct:   16 EGIRAILLGPPGAGKGTQAPKLAEKYCVCHLATGDMLRAMVASGSELGKRLKATMDAGKLVSDEMVVELIEKNLDTPPCKKGFLLDGFPRTVKQAEMLDELLEKRQEKLDSVIEFKVDDSLLVRRICGRLIHASSGRSYHEEFNPPKEPMKDDVTGEALIRRSDDNESTLKSRLEAYHTMTSPLVDYYQRHGIHTAVDAAQSPDVVFASILAAFSKA 232          
BLAST of Adenylate kinase vs. UniProt/SwissProt
Match: sp|Q28F55|KAD2_XENTR (Adenylate kinase 2, mitochondrial OS=Xenopus tropicalis OX=8364 GN=ak2 PE=2 SV=1)

HSP 1 Score: 298.516 bits (763), Expect = 5.638e-101
Identity = 138/218 (63.30%), Postives = 169/218 (77.52%), Query Frame = 1
Query:  136 QNINAILIGPAGSGKGTQAPKLVERYKICHLATGDMLRAIVSSGSPLGRQVNEIMQQGGLISDEIVCKLIEENLSKQECKNGFILDGFPRTVGQAEKLDQLLEKRNSKINAVVEFNVDDSVLERRITGRLFHLSSGRSYHEEFNPPKQPMIDDITGEKLVRRKDDNVETLKSRLQSYRTDTAPLIGYYQKRNVHYQVKASQKPDRVFEDILNFFEKSR 789
            + I AIL+GP G+GKGTQAPKL E+Y +CHLATGDMLRA+V+SGS LG ++   M  G L+SDE+V +LIE+NL    CK GF+LDGFPRTV QAE LD+LLEKR  K+++V+EF VDDS+L RRI GRL H SSGRSYHEEFNPPK+ M DD+TGE L+RR DDN  TLKSRL++Y T T+PL+ YYQ+  +H  V A+Q PD VF  IL  F K+R
Sbjct:   16 EGIRAILLGPPGAGKGTQAPKLAEKYCVCHLATGDMLRAMVASGSELGMRLKATMDAGKLVSDEMVVELIEKNLDTPPCKKGFLLDGFPRTVKQAEMLDELLEKRQEKLDSVIEFKVDDSLLVRRICGRLIHASSGRSYHEEFNPPKEAMKDDVTGEPLMRRSDDNETTLKSRLEAYHTMTSPLVEYYQRHGIHTAVDAAQSPDVVFASILAAFSKAR 233          
BLAST of Adenylate kinase vs. UniProt/SwissProt
Match: sp|P08166|KAD2_BOVIN (Adenylate kinase 2, mitochondrial OS=Bos taurus OX=9913 GN=AK2 PE=1 SV=2)

HSP 1 Score: 295.819 bits (756), Expect = 8.188e-100
Identity = 135/222 (60.81%), Postives = 170/222 (76.58%), Query Frame = 1
Query:  121 VSESKQNINAILIGPAGSGKGTQAPKLVERYKICHLATGDMLRAIVSSGSPLGRQVNEIMQQGGLISDEIVCKLIEENLSKQECKNGFILDGFPRTVGQAEKLDQLLEKRNSKINAVVEFNVDDSVLERRITGRLFHLSSGRSYHEEFNPPKQPMIDDITGEKLVRRKDDNVETLKSRLQSYRTDTAPLIGYYQKRNVHYQVKASQKPDRVFEDILNFFEKS 786
            V ES + + A+L+GP G+GKGTQAPKL + + +CHLATGDMLRA+V+SGS LG+++   M  G L+SDE+V +LIE+NL    CKNGF+LDGFPRTV QAE LD L+EKR  K+++V+EF++ DS+L RRITGRL H  SGRSYHEEFNPPK+PM DDITGE L+RR DDN + LK RL++Y T T PL+ YY KR +H  + ASQ PD VF  IL  F K+
Sbjct:   11 VPESPKGVRAVLLGPPGAGKGTQAPKLAKNFCVCHLATGDMLRAMVASGSELGKKLKATMDAGKLVSDEMVLELIEKNLETPPCKNGFLLDGFPRTVRQAEMLDDLMEKRKEKLDSVIEFSIPDSLLIRRITGRLIHPQSGRSYHEEFNPPKEPMKDDITGEPLIRRSDDNKKALKIRLEAYHTQTTPLVEYYSKRGIHSAIDASQTPDVVFASILAAFSKA 232          
BLAST of Adenylate kinase vs. UniProt/SwissProt
Match: sp|Q9WTP6|KAD2_MOUSE (Adenylate kinase 2, mitochondrial OS=Mus musculus OX=10090 GN=Ak2 PE=1 SV=5)

HSP 1 Score: 295.819 bits (756), Expect = 8.348e-100
Identity = 137/227 (60.35%), Postives = 173/227 (76.21%), Query Frame = 1
Query:  112 NFFVSESK--QNINAILIGPAGSGKGTQAPKLVERYKICHLATGDMLRAIVSSGSPLGRQVNEIMQQGGLISDEIVCKLIEENLSKQECKNGFILDGFPRTVGQAEKLDQLLEKRNSKINAVVEFNVDDSVLERRITGRLFHLSSGRSYHEEFNPPKQPMIDDITGEKLVRRKDDNVETLKSRLQSYRTDTAPLIGYYQKRNVHYQVKASQKPDRVFEDILNFFEKS 786
            N   SE +  + I A+L+GP G+GKGTQAPKL E + +CHLATGDMLRA+V+SGS LG+++   M  G L+SDE+V +LIE+NL    CKNGF+LDGFPRTV QAE LD L+EKR  K+++V+EF++ DS+L RRITGRL H  SGRSYHEEFNPPK+PM DDITGE L+RR DDN + LK+RL++Y T T PL+ YY+KR +H  + ASQ PD VF  IL  F K+
Sbjct:    4 NVLASEPEIPKGIRAVLLGPPGAGKGTQAPKLAENFCVCHLATGDMLRAMVASGSELGKKLKATMDAGKLVSDEMVVELIEKNLETPSCKNGFLLDGFPRTVRQAEMLDDLMEKRKEKLDSVIEFSIQDSLLIRRITGRLIHPKSGRSYHEEFNPPKEPMKDDITGEPLIRRSDDNEKALKTRLEAYHTQTTPLVEYYRKRGIHCAIDASQTPDIVFASILAAFSKA 230          
BLAST of Adenylate kinase vs. UniProt/SwissProt
Match: sp|B5XCA1|KAD2_SALSA (Adenylate kinase 2, mitochondrial OS=Salmo salar OX=8030 GN=ak2 PE=2 SV=1)

HSP 1 Score: 294.664 bits (753), Expect = 2.133e-99
Identity = 137/219 (62.56%), Postives = 168/219 (76.71%), Query Frame = 1
Query:  112 NFFVSESKQNINAILIGPAGSGKGTQAPKLVERYKICHLATGDMLRAIVSSGSPLGRQVNEIMQQGGLISDEIVCKLIEENLSKQECKNGFILDGFPRTVGQAEKLDQLLEKRNSKINAVVEFNVDDSVLERRITGRLFHLSSGRSYHEEFNPPKQPMIDDITGEKLVRRKDDNVETLKSRLQSYRTDTAPLIGYYQKRNVHYQVKASQKPDRVFEDIL 768
            N  VS+ K+ I AIL+GP G+GKGTQAP+L E+Y +CHLATGDMLRA+V+SGS LG+++ E M  G L+SDE+V +LIE+NL    CK GF+LDGFPRTV QAE LD LLEKR  K+++V+EF+VDDS+L RRI GRL H  SGRSYHEEFNPPK+PM DD+TGE L+RR DDN  TL+SRL++Y   T PL+ YY  R +H  V A Q PD VF  IL
Sbjct:    8 NEAVSDVKKGIRAILLGPPGAGKGTQAPRLAEQYCVCHLATGDMLRAMVASGSGLGKRLKETMDAGKLVSDEMVVELIEKNLDTPPCKKGFLLDGFPRTVKQAEMLDDLLEKRTEKLDSVIEFSVDDSLLVRRICGRLIHQPSGRSYHEEFNPPKEPMKDDVTGEPLMRRSDDNASTLRSRLEAYHGQTVPLVKYYSARGLHKAVDAGQSPDVVFASIL 226          
BLAST of Adenylate kinase vs. TrEMBL
Match: A0A2B4RS52 (Adenylate kinase OS=Stylophora pistillata OX=50429 GN=ak2 PE=3 SV=1)

HSP 1 Score: 306.605 bits (784), Expect = 3.078e-101
Identity = 137/220 (62.27%), Postives = 176/220 (80.00%), Query Frame = 1
Query:  130 SKQNINAILIGPAGSGKGTQAPKLVERYKICHLATGDMLRAIVSSGSPLGRQVNEIMQQGGLISDEIVCKLIEENLSKQECKNGFILDGFPRTVGQAEKLDQLLEKRNSKINAVVEFNVDDSVLERRITGRLFHLSSGRSYHEEFNPPKQPMIDDITGEKLVRRKDDNVETLKSRLQSYRTDTAPLIGYYQKRNVHYQVKASQKPDRVFEDILNFFEKSR 789
            +K+ +N IL+GP G+GKGTQAPKL E+Y +CHLATGDMLRA+V+SGS LG++V ++M  G L+SD +V +LI++NL K  C NGF+LDGFPRTV QAEKLD+LLEKR + ++AVVEF +DDS+L RRITGRL H  SGR+YH EFNPPK+PM DDITGE LVRR DDN  TL  RL++Y   T+PL+ YY+KR +H ++ A++ PD VF  +LN FEK+R
Sbjct:   36 NKKGVNGILLGPPGAGKGTQAPKLAEKYCVCHLATGDMLRAVVASGSTLGKKVKQVMDSGQLVSDALVVELIDDNLGKPACANGFLLDGFPRTVVQAEKLDELLEKRKTALDAVVEFGIDDSLLVRRITGRLLHKPSGRTYHNEFNPPKKPMTDDITGEPLVRRSDDNEATLTKRLEAYHKQTSPLVDYYKKRGLHSRIDAAETPDVVFNSVLNEFEKAR 255          
BLAST of Adenylate kinase vs. TrEMBL
Match: A0A3M6TCQ4 (Adenylate kinase OS=Pocillopora damicornis OX=46731 GN=pdam_00022864 PE=3 SV=1)

HSP 1 Score: 306.22 bits (783), Expect = 3.706e-101
Identity = 137/219 (62.56%), Postives = 176/219 (80.37%), Query Frame = 1
Query:  133 KQNINAILIGPAGSGKGTQAPKLVERYKICHLATGDMLRAIVSSGSPLGRQVNEIMQQGGLISDEIVCKLIEENLSKQECKNGFILDGFPRTVGQAEKLDQLLEKRNSKINAVVEFNVDDSVLERRITGRLFHLSSGRSYHEEFNPPKQPMIDDITGEKLVRRKDDNVETLKSRLQSYRTDTAPLIGYYQKRNVHYQVKASQKPDRVFEDILNFFEKSR 789
            K+ +N IL+GP G+GKGTQAPKL E+Y +CHLATGDMLRA+V+SGS LG++V ++M  G L+SD +V +LI++NL K EC NGF+LDGFPRTV QAEKLD+LLE+R + ++AVVEF +DDS+L RRITGRL H  SGR+YH EFNPPK+PM DDITGE LVRR DDN  TL  RL++Y   T+PL+ YY+KR +H ++ A++ PD VF  +LN FEK+R
Sbjct:   37 KKGVNGILLGPPGAGKGTQAPKLAEKYCVCHLATGDMLRAVVASGSTLGKKVKQVMDSGQLVSDALVVELIDDNLGKPECANGFLLDGFPRTVVQAEKLDELLEQRKTGLDAVVEFGIDDSLLVRRITGRLLHKPSGRTYHNEFNPPKKPMTDDITGEPLVRRSDDNEATLTKRLEAYHKQTSPLVDYYKKRGLHSRIDAAETPDVVFNSVLNEFEKAR 255          
BLAST of Adenylate kinase vs. TrEMBL
Match: A0A310UE25 (Adenylate kinase 2, mitochondrial OS=Xenopus laevis OX=8355 GN=AK2 PE=1 SV=1)

HSP 1 Score: 302.368 bits (773), Expect = 4.129e-100
Identity = 138/217 (63.59%), Postives = 170/217 (78.34%), Query Frame = 1
Query:  136 QNINAILIGPAGSGKGTQAPKLVERYKICHLATGDMLRAIVSSGSPLGRQVNEIMQQGGLISDEIVCKLIEENLSKQECKNGFILDGFPRTVGQAEKLDQLLEKRNSKINAVVEFNVDDSVLERRITGRLFHLSSGRSYHEEFNPPKQPMIDDITGEKLVRRKDDNVETLKSRLQSYRTDTAPLIGYYQKRNVHYQVKASQKPDRVFEDILNFFEKS 786
            + I AIL+GP G+GKGTQAPKL E+Y +CHLATGDMLRA+V+SGS LG+++   M  G L+SDE+V +LIE+NL    CK GF+LDGFPRTV QAE LD+LLEKR  K+++V+EF VDDS+L RRI GRL H SSGRSYHEEFNPPK+PM DD+TGE L+RR DDN  TLKSRL++Y T T+PL+ YYQ+  +H  V A+Q PD VF  IL  F K+
Sbjct:   16 EGIRAILLGPPGAGKGTQAPKLAEKYCVCHLATGDMLRAMVASGSELGKRLKATMDAGKLVSDEMVVELIEKNLDTPPCKKGFLLDGFPRTVKQAEMLDELLEKRQEKLDSVIEFKVDDSLLVRRICGRLIHASSGRSYHEEFNPPKEPMKDDVTGEALIRRSDDNESTLKSRLEAYHTMTSPLVDYYQRHGIHTAVDAAQSPDVVFASILAAFSKA 232          
BLAST of Adenylate kinase vs. TrEMBL
Match: C3Y4K4 (Adenylate kinase OS=Branchiostoma floridae OX=7739 GN=BRAFLDRAFT_115743 PE=3 SV=1)

HSP 1 Score: 302.368 bits (773), Expect = 5.780e-100
Identity = 139/220 (63.18%), Postives = 171/220 (77.73%), Query Frame = 1
Query:  127 ESKQNINAILIGPAGSGKGTQAPKLVERYKICHLATGDMLRAIVSSGSPLGRQVNEIMQQGGLISDEIVCKLIEENLSKQECKNGFILDGFPRTVGQAEKLDQLLEKRNSKINAVVEFNVDDSVLERRITGRLFHLSSGRSYHEEFNPPKQPMIDDITGEKLVRRKDDNVETLKSRLQSYRTDTAPLIGYYQKRNVHYQVKASQKPDRVFEDILNFFEKS 786
            E    I AIL+GP G+GKGTQAPKL E+Y +CHLATGDMLRA+V+SGS LG+++ E M QG L+SDE+V ++I+ NL K ECKNGF+LDGFPRTV QA+KLD LL+ R SK+++VVEF +DDS+L RRI GRL H  SGRSYHEEFNPPK  M DD+TGE L+RR DDN ETL  RL++Y T T PL+ YYQKRN+H +V A+Q PD VF  I   F ++
Sbjct:   13 EQSVGIRAILLGPPGAGKGTQAPKLAEKYCVCHLATGDMLRAVVASGSELGKRLKETMDQGKLVSDEMVVEMIDNNLDKPECKNGFLLDGFPRTVTQAKKLDDLLDTRESKLDSVVEFGIDDSLLVRRICGRLIHKPSGRSYHEEFNPPKVDMTDDVTGEPLIRRSDDNAETLTKRLEAYHTQTKPLVDYYQKRNLHAKVDAAQSPDIVFASIQAIFAQA 232          
BLAST of Adenylate kinase vs. TrEMBL
Match: T1G1C3 (Adenylate kinase OS=Helobdella robusta OX=6412 GN=20214871 PE=3 SV=1)

HSP 1 Score: 301.982 bits (772), Expect = 8.243e-100
Identity = 142/226 (62.83%), Postives = 177/226 (78.32%), Query Frame = 1
Query:  106 MGNF-FVSESKQNINAILIGPAGSGKGTQAPKLVERYKICHLATGDMLRAIVSSGSPLGRQVNEIMQQGGLISDEIVCKLIEENLSKQECKNGFILDGFPRTVGQAEKLDQLLEKRNSKINAVVEFNVDDSVLERRITGRLFHLSSGRSYHEEFNPPKQPMIDDITGEKLVRRKDDNVETLKSRLQSYRTDTAPLIGYYQKRNVHYQVKASQKPDRVFEDILNFFE 780
            MG F F  + +  +NAIL+GP GSGKGTQAPKL E++  CHL+TGDMLRA+V+SGS LG++V ++M  G L+SD++V +LI++NL+K ECKNGF+LDGFPRTV QAEKLDQLL++RN  +NAV+EF +DD +L +RITGRL HL SGRSYH EFNPPK PM DDITGE LV R DDN E LK RL +Y   T PLI YY KR++H  V ASQ P++VF +I+N  E
Sbjct:    1 MGLFSFFKKKETGVNAILLGPPGSGKGTQAPKLSEKFCSCHLSTGDMLRAVVASGSDLGKRVKKVMDDGNLVSDDLVVELIDDNLNKPECKNGFLLDGFPRTVLQAEKLDQLLQRRNQILNAVIEFRIDDDLLVKRITGRLIHLKSGRSYHTEFNPPKVPMKDDITGEPLVHRSDDNPEALKKRLDNYHKQTTPLIDYYGKRDLHRHVDASQSPNKVFSEIVNLLE 226          
BLAST of Adenylate kinase vs. Ensembl Cavefish
Match: ak2 (adenylate kinase 2 [Source:NCBI gene;Acc:103022510])

HSP 1 Score: 288.115 bits (736), Expect = 8.308e-98
Identity = 136/222 (61.26%), Postives = 168/222 (75.68%), Query Frame = 1
Query:  121 VSESKQNINAILIGPAGSGKGTQAPKLVERYKICHLATGDMLRAIVSSGSPLGRQVNEIMQQGGLISDEIVCKLIEENLSKQECKNGFILDGFPRTVGQAEKLDQLLEKRNSKINAVVEFNVDDSVLERRITGRLFHLSSGRSYHEEFNPPKQPMIDDITGEKLVRRKDDNVETLKSRLQSYRTDTAPLIGYYQKRNVHYQVKASQKPDRVFEDILNFFEKS 786
            VS  ++ I AIL+GP G+GKGTQAP+L E++ +CHLATGDMLRA+V+SGS LG+++ + M  G L+SDE+V +LIE+NL    CKNGF+LDGFPRTV QAE LD LL+KR  K+++VVEF+VDDS+L RRI GRL H  SGRSYHEEFNPPK+ M DD+TGE L RR DDN  TL+SRL+SY   TAPL+ YY  R +H  V AS  PD VF  IL  F  +
Sbjct:   11 VSGVRKGIRAILLGPPGAGKGTQAPRLAEKFCVCHLATGDMLRAMVASGSELGQRLKQTMDAGKLVSDEMVVELIEKNLDTPPCKNGFLLDGFPRTVKQAEMLDDLLDKRTEKLDSVVEFSVDDSLLVRRICGRLIHQPSGRSYHEEFNPPKEHMKDDVTGEPLSRRSDDNENTLRSRLESYHRQTAPLVEYYSARGLHRAVDASLSPDLVFASILAAFSAA 232          
BLAST of Adenylate kinase vs. Ensembl Cavefish
Match: ak2 (adenylate kinase 2 [Source:NCBI gene;Acc:103022510])

HSP 1 Score: 287.73 bits (735), Expect = 1.444e-97
Identity = 136/222 (61.26%), Postives = 168/222 (75.68%), Query Frame = 1
Query:  121 VSESKQNINAILIGPAGSGKGTQAPKLVERYKICHLATGDMLRAIVSSGSPLGRQVNEIMQQGGLISDEIVCKLIEENLSKQECKNGFILDGFPRTVGQAEKLDQLLEKRNSKINAVVEFNVDDSVLERRITGRLFHLSSGRSYHEEFNPPKQPMIDDITGEKLVRRKDDNVETLKSRLQSYRTDTAPLIGYYQKRNVHYQVKASQKPDRVFEDILNFFEKS 786
            VS  ++ I AIL+GP G+GKGTQAP+L E++ +CHLATGDMLRA+V+SGS LG+++ + M  G L+SDE+V +LIE+NL    CKNGF+LDGFPRTV QAE LD LL+KR  K+++VVEF+VDDS+L RRI GRL H  SGRSYHEEFNPPK+ M DD+TGE L RR DDN  TL+SRL+SY   TAPL+ YY  R +H  V AS  PD VF  IL  F  +
Sbjct:   11 VSGVRKGIRAILLGPPGAGKGTQAPRLAEKFCVCHLATGDMLRAMVASGSELGQRLKQTMDAGKLVSDEMVVELIEKNLDTPPCKNGFLLDGFPRTVKQAEMLDDLLDKRTEKLDSVVEFSVDDSLLVRRICGRLIHQPSGRSYHEEFNPPKEHMKDDVTGEPLSRRSDDNENTLRSRLESYHRQTAPLVEYYSARGLHRAVDASLSPDLVFASILAAFSAA 232          
BLAST of Adenylate kinase vs. Ensembl Cavefish
Match: ak3 (adenylate kinase 3 [Source:NCBI gene;Acc:103033473])

HSP 1 Score: 162.925 bits (411), Expect = 6.082e-49
Identity = 76/212 (35.85%), Postives = 133/212 (62.74%), Query Frame = 1
Query:  148 AILIGPAGSGKGTQAPKLVERYKICHLATGDMLRAIVSSGSPLGRQVNEIMQQGGLISDEIVCKLIEENLSKQECKNGFILDGFPRTVGQAEKLDQLLEKRNSKINAVVEFNVDDSVLERRITGRLFHLSSGRSYHEEFNPPKQPMIDDITGEKLVRRKDDNVETLKSRLQSYRTDTAPLIGYYQKRNVHYQVKASQKPDRVFEDILNFFEK 783
            A+++GP GSGKGT + ++ + + + HL++GD+LRA + + + LG  +   + QG L+ D+++ +LI  NL   +  + ++LDGFPRTV QAE LD +       ++ V+  +V    ++ R+T R  HL SGR Y+ +FNPPK P +DD+TGE L++R+DD  ET+  RL++Y   T P++ YY+ + V  +  +  + ++++  +  F  +
Sbjct:    9 AVIMGPPGSGKGTVSNRITDSFGLKHLSSGDILRANIKAKTELGLLMKSCIDQGQLVPDDVISRLILSNLRNMD-HSSWLLDGFPRTVAQAESLDSM-----CTVDTVINLDVPFQTIKERLTSRWLHLPSGRVYNTDFNPPKIPGLDDVTGEPLIQREDDTPETVTRRLKAYEFQTQPVLEYYRSKGV-LETFSGTETNKIWPHVHTFLTR 213          
BLAST of Adenylate kinase vs. Ensembl Cavefish
Match: ak4 (adenylate kinase 4 [Source:NCBI gene;Acc:103040221])

HSP 1 Score: 137.887 bits (346), Expect = 3.510e-39
Identity = 69/215 (32.09%), Postives = 126/215 (58.60%), Query Frame = 1
Query:  121 VSESKQNINAILIGPAGSGKGTQAPKLVERYKICHLATGDMLRAIVSSGSPLGRQVNEIMQQGGLISDEIVCKLIEENLSKQECKNGFILDGFPRTVGQAEKLDQLLEKRNSKINAVVEFNVDDSVLERRITGRLFHLSSGRSYHEEFNPPKQPMIDDITGEKLVRRKDDNVETLKSRLQSYRTDTAPLIGYYQKRNVHYQVKASQKPDRVFEDI 765
            + ++K    A+++GP GSGKGT + ++   + + HL++GD LR  ++S +  G      +++G L+ D ++ +L+   L +  C + ++LDGFPRT+ QAE L+      + +++ V+  N+    L+ R++ R  H +SGR Y+  FNPP+   +DDITGE L+++ DD  E L +RL+ Y+    P+I  Y+ + + +    +   DR++  I
Sbjct:    5 LDDTKLLFRAVIMGPPGSGKGTISERIARGFGLQHLSSGDFLRENIASNTEAGVLAKTYIEKGLLVPDHVMTRLLLPRLEEMTC-HSWLLDGFPRTLAQAEALNS-----SCELDLVISLNIPLETLKERLSHRWIHQASGRVYNMCFNPPRVQGVDDITGEPLIQQDDDKPEALVARLRHYKDVAKPVIDVYKAKGILHTFSDTDT-DRIWPYI 212          
BLAST of Adenylate kinase vs. Ensembl Cavefish
Match: ak4 (adenylate kinase 4 [Source:NCBI gene;Acc:103040221])

HSP 1 Score: 136.346 bits (342), Expect = 1.227e-38
Identity = 68/206 (33.01%), Postives = 122/206 (59.22%), Query Frame = 1
Query:  148 AILIGPAGSGKGTQAPKLVERYKICHLATGDMLRAIVSSGSPLGRQVNEIMQQGGLISDEIVCKLIEENLSKQECKNGFILDGFPRTVGQAEKLDQLLEKRNSKINAVVEFNVDDSVLERRITGRLFHLSSGRSYHEEFNPPKQPMIDDITGEKLVRRKDDNVETLKSRLQSYRTDTAPLIGYYQKRNVHYQVKASQKPDRVFEDI 765
            A+++GP GSGKGT + ++   + + HL++GD LR  ++S +  G      +++G L+ D ++ +L+   L +  C + ++LDGFPRT+ QAE L+      + +++ V+  N+    L+ R++ R  H +SGR Y+  FNPP+   +DDITGE L+++ DD  E L +RL+ Y+    P+I  Y+ + + +    +   DR++  I
Sbjct:    7 AVIMGPPGSGKGTISERIARGFGLQHLSSGDFLRENIASNTEAGVLAKTYIEKGLLVPDHVMTRLLLPRLEEMTC-HSWLLDGFPRTLAQAEALNS-----SCELDLVISLNIPLETLKERLSHRWIHQASGRVYNMCFNPPRVQGVDDITGEPLIQQDDDKPEALVARLRHYKDVAKPVIDVYKAKGILHTFSDTDT-DRIWPYI 205          
BLAST of Adenylate kinase vs. Ensembl Sea Lamprey
Match: ak2 (adenylate kinase 2 [Source:NCBI gene;Acc:321793])

HSP 1 Score: 119.783 bits (299), Expect = 1.933e-34
Identity = 57/110 (51.82%), Postives = 71/110 (64.55%), Query Frame = 1
Query:  511 ITGRLFHLSSGRSYHEEFNPPKQPMIDDITGEKLVRRKDDNVETLKSRLQSYRTDTAPLIGYYQKRNVHYQVKASQKPDRVFEDILNFFEKSRK*ISFERFHSRNLEIYL 840
            +  RL H  SGRSYHEEFNPP  PM DD+TGE L+RR DDN + L SRL SY T T+PL+GYYQ+R +H  V A+Q PD VF  I           +F R  S++L ++L
Sbjct:    1 VCSRLIHKESGRSYHEEFNPPIVPMRDDVTGEPLIRRSDDNEQALASRLASYHTQTSPLVGYYQRRGLHTAVDAAQSPDVVFASIQ---------AAFARAESKDLVVFL 101          
BLAST of Adenylate kinase vs. Ensembl Sea Lamprey
Match: ak5l (adenylate kinase 5, like [Source:ZFIN;Acc:ZDB-GENE-050410-2])

HSP 1 Score: 73.9442 bits (180), Expect = 3.652e-16
Identity = 56/207 (27.05%), Postives = 94/207 (45.41%), Query Frame = 1
Query:  160 GPAGSGKGTQAPKLVERYKICHLATGDMLRAIVSSGSPLGRQ---VNEIMQQGGLISDEIVCKLIEENLSKQECKNGFILDGFPRTVGQAEKLDQLLEKRNSKINAVVEFNVDDSVLERRITGRLFHLSSGRSYHEEFNPPKQPMIDDITGEKLVR--RKDDNVETLKSRLQSYRTDTAPLIGYYQKRNVHYQVKASQKPDRVFEDI 765
            G  GSGKGTQ+ KL E Y +  ++ G++LR  V   +P  R+   + +I+ +G L   E     ++++  +     GF++DGFPR + QA       E++    +AV+        L +R+                             GE+  R  R DDN   ++ RL ++R  T PL+ +YQ+R +     A ++   +F DI
Sbjct:    1 GGPGSGKGTQSRKLSESYGLVCVSLGEVLRQHVLQRAPSNRKWRLIAQIISKGELAPQETAIWELKQHFLQNPDAPGFVIDGFPREISQALA----FEEQVGAPDAVILLACASERLRQRL-----------------------------GERADRHGRPDDNPRAVERRLATFRQHTVPLVQHYQERGLLLTFDADREEGELFGDI 174          
BLAST of Adenylate kinase vs. Ensembl Sea Lamprey
Match: spef2 (sperm flagellar 2 [Source:NCBI gene;Acc:553375])

HSP 1 Score: 55.8398 bits (133), Expect = 5.761e-9
Identity = 32/79 (40.51%), Postives = 49/79 (62.03%), Query Frame = 1
Query:  244 LRAIVSSGSPLGRQVNEIMQQGGLISDEIVCKLIEENLSKQECKNGFILDGFPRTVGQAEKL-------DQLLEKRNSK 459
            L  I S+   LGRQ +E++ QGG++ D+++  L+ + L +   + G+ILDGFP TV QA+ L       D+ LE+ NSK
Sbjct:  575 LSNITSNVVELGRQASEVLAQGGVVPDQLLVFLVLQALRELPEQTGWILDGFPATVQQAKLLEKALTGWDEDLEEGNSK 653          
BLAST of Adenylate kinase vs. Ensembl Yeast
Match: ADK1 (Adenylate kinase, required for purine metabolism; localized to the cytoplasm and the mitochondria; lacks cleavable signal sequence; protein abundance increases in response to DNA replication stress; mutations affecting Adk1p catalytic activity deregulate expression of phosphate utilization genes PHO5 and PHO84; human homolog AK1 can complement yeast adk1 mutant [Source:SGD;Acc:S000002634])

HSP 1 Score: 249.98 bits (637), Expect = 7.678e-84
Identity = 116/219 (52.97%), Postives = 156/219 (71.23%), Query Frame = 1
Query:  130 SKQNINAILIGPAGSGKGTQAPKLVERYKICHLATGDMLRAIVSSGSPLGRQVNEIMQQGGLISDEIVCKLIEENLSKQ-ECKNGFILDGFPRTVGQAEKLDQLLEKRNSKINAVVEFNVDDSVLERRITGRLFHLSSGRSYHEEFNPPKQPMIDDITGEKLVRRKDDNVETLKSRLQSYRTDTAPLIGYYQKRNVHYQVKASQKPDRVFEDILNFFEK 783
            S ++I  +LIGP G+GKGTQAP L ER+   HLATGDMLR+ ++ G+ LG +  +IM QGGL+SD+I+  +I++ L+    CKNGFILDGFPRT+ QAEKLDQ+L+++ + +   +E  VDD +L  RITGRL H +SGRSYH+ FNPPK+ M DD+TGE LV+R DDN + LK RL +Y   T P++ +Y+K  +   V ASQ P  V+ DILN   K
Sbjct:    3 SSESIRMVLIGPPGAGKGTQAPNLQERFHAAHLATGDMLRSQIAKGTQLGLEAKKIMDQGGLVSDDIMVNMIKDELTNNPACKNGFILDGFPRTIPQAEKLDQMLKEQGTPLEKAIELKVDDELLVARITGRLIHPASGRSYHKIFNPPKEDMKDDVTGEALVQRSDDNADALKKRLAAYHAQTEPIVDFYKKTGIWAGVDASQPPATVWADILNKLGK 221          
BLAST of Adenylate kinase vs. Ensembl Yeast
Match: ADK2 (Mitochondrial adenylate kinase; catalyzes the reversible synthesis of GTP and AMP from GDP and ADP; may serve as a back-up for synthesizing GTP or ADP depending on metabolic conditions; 3' sequence of ADK2 varies with strain background [Source:SGD;Acc:S000000972])

HSP 1 Score: 155.992 bits (393), Expect = 3.509e-47
Identity = 81/205 (39.51%), Postives = 125/205 (60.98%), Query Frame = 1
Query:  160 GPAGSGKGTQAPKLVERY-KICHLATGDMLRAIVSSGSPLGRQVNEIMQQGGLISDEIVCKLIEENLSKQ---ECKNGFILDGFPRTVGQAEKLDQLLEKRNSKINAVVEFNVDDSVLERRITGRLFHLSSGRSYHEEFNPPKQPMIDDITGEKLVRRKDDNVETLKSRLQSYRTDTAPLIGYYQKRNVHYQVKASQKPDRVFED 762
            G  GSGKGTQ  +L+++  ++  +++GD+LR  + S S LGR+    + QG L+ D+++ +LI   LS     +    ++LDGFPRT  QA  LD+LL++ ++ +N VVE +V +S +  RI  R  H+ SGR Y+ ++NPPK P +DDITGE L +R DD  E  K RL+ Y+    PL  YY+K  +   V + +  D +F +
Sbjct:   21 GAPGSGKGTQTSRLLKQIPQLSSISSGDILRQEIKSESTLGREATTYIAQGKLLPDDLITRLITFRLSALGWLKPSAMWLLDGFPRTTAQASALDELLKQHDASLNLVVELDVPESTILERIENRYVHVPSGRVYNLQYNPPKVPGLDDITGEPLTKRLDDTAEVFKKRLEEYKKTNEPLKDYYKKSGIFGTV-SGETSDIIFRN 224          
BLAST of Adenylate kinase vs. Ensembl Yeast
Match: URA6 (Uridylate kinase; catalyzes the seventh enzymatic step in the de novo biosynthesis of pyrimidines, converting uridine monophosphate (UMP) into uridine-5'-diphosphate (UDP) [Source:SGD;Acc:S000001507])

HSP 1 Score: 85.1149 bits (209), Expect = 2.130e-20
Identity = 58/209 (27.75%), Postives = 103/209 (49.28%), Query Frame = 1
Query:  151 ILIGPAGSGKGTQAPKLVERYKICHLATGDMLRAIVS-SGSPLGRQVNEIMQQGGLISDEIVCKLIEENLSK--QECKNGFILDGFPRTVGQAEKLDQLLEKRNSKINAVVEFNVDDSVLERRITGRLFHLSSGRSYHEEFNPPKQPMIDDITGE-KLVRRKDDNVETLKSRLQSYRTDTAPLIGYYQKRNVHYQVKASQKPDRVFEDI 765
             ++G  G+GKGTQ  KLV+ Y   HL+ GD+LRA    +GS  G  +   +++G ++  EI   L+   +S   +  K+ F++DGFPR      K+DQ +                    ER I    F L         F+ P+  M++ +    K   R DDN+E++K R  +++  + P+I Y++ ++   +V+  +  + V++D+
Sbjct:   20 FVLGGPGAGKGTQCEKLVKDYSFVHLSAGDLLRAEQGRAGSQYGELIKNCIKEGQIVPQEITLALLRNAISDNVKANKHKFLIDGFPR------KMDQAIS------------------FERDIVESKFILF--------FDCPEDIMLERLLERGKTSGRSDDNIESIKKRFNTFKETSMPVIEYFETKSKVVRVRCDRSVEDVYKDV 196          
BLAST of Adenylate kinase vs. Ensembl Nematostella
Match: EDO30550 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7T0G9])

HSP 1 Score: 265.388 bits (677), Expect = 2.491e-89
Identity = 124/217 (57.14%), Postives = 164/217 (75.58%), Query Frame = 1
Query:  136 QNINAILIGPAGSGKGTQAPKLVERYKICHLATGDMLRAIVSSGSPLGRQVNEIMQQGGLISDEIVCKLIEENLSKQECKNGFILDGFPRTVGQAEKLDQLLEKRNSKINAVVEFNVDDSVLERRITGRLFHLSSGRSYHEEFNPPKQPMIDDITGEKLVRRKDDNVETLKSRLQSYRTDTAPLIGYYQKRNVHYQVKASQKPDRVFEDILNFFEKS 786
            + + AIL+GP GSGKGTQ  +      +C L   DMLRA+V+SGS LG++V  +M  G L+SD++V +LI++NL+K EC+NG++LDGFPRTV QAEKLD LLEKRN++++AVVEFN+ DS+L +RITGRL H SSGR+YH EFNPPK+ M DDITGE L RR DDN  TL  RLQ+Y + T PLI YY KR +H+++ AS+ PD V+  +L  F+ +
Sbjct:   13 RGVRAILLGPPGSGKGTQVKRRRISIVVCLLFC-DMLRAVVASGSALGKKVKSVMDAGQLVSDDLVVELIDDNLTKPECQNGWLLDGFPRTVAQAEKLDGLLEKRNAQLDAVVEFNIADSLLVKRITGRLLHKSSGRTYHTEFNPPKEHMKDDITGEPLERRSDDNEATLTKRLQAYHSQTTPLIDYYTKRGIHHKIDASKPPDTVYSSVLKAFDDA 228          
BLAST of Adenylate kinase vs. Ensembl Nematostella
Match: EDO42583 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S170])

HSP 1 Score: 148.288 bits (373), Expect = 5.641e-44
Identity = 80/186 (43.01%), Postives = 113/186 (60.75%), Query Frame = 1
Query:  157 IGPAGSGKGTQAPKLVERYKICHLATGDMLRAIVSSGSPLGRQVNEIMQQGGLISDEIVCKLIEENLSKQECKNGFILDGFPRTVGQAEKLDQLLEKRNSKINAVVEFNVDDSVLERRITGRLFHLSSGRSYHEEFNPPKQPMIDDITGEKLVRRKDDNVETLKSRLQSYRTDTAPLIGYYQKRNV 714
            +GP GSGKGT + ++V  + + HL++G++LR  V + + LG +    + +G L+ DE++  LI   L  +  K  ++LDGFPRTVGQAE L +       KI+ VV  +V  + +  RI  R  H  SGR Y+ EFNPPK    DDITGE L +R+DD  ET+ +RL+ Y   T PLI YY K+ V
Sbjct:    1 MGPPGSGKGTVSERIVRDFGVEHLSSGELLRHHVQNHTDLGEEAQAYILKGELVPDELMVDLILHELDAK--KGNWLLDGFPRTVGQAETLSE-----KHKIDVVVNMDVPFATIVDRIKQRWVHAVSGRVYNLEFNPPKVEGKDDITGEPLTQREDDKPETVMARLKKYEEQTKPLIEYYNKKGV 179          
BLAST of Adenylate kinase vs. Ensembl Nematostella
Match: EDO38864 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SBK9])

HSP 1 Score: 103.219 bits (256), Expect = 5.307e-27
Identity = 64/209 (30.62%), Postives = 106/209 (50.72%), Query Frame = 1
Query:  157 IGPAGSGKGTQAPKLVERYKICHLATGDMLRAIVSSGSPLGRQVNEIMQQGGLISDEIVCKLIEENLSKQECKNGFILDGFPRTVGQAEKLDQLLEKRNSKINAVVEFNVDDSVLERRITGRLFHLSSGRSYHEEFNPPKQPMIDDITGEKLVRRKDDNVETLKSRLQSYRTDTAPLIGYYQKRNVHYQVKASQKPDRVFEDILNFFEK 783
            +G  GSGKGTQ  ++VE++   H +TGD+LR  V+SGS  G+ +  +M++G L+ + I+ +L+   + KQ    GF++DGFPR + Q  +     EK  +    ++ F      ++ R+  R    +SGR                          DDN ET+ SRL+++ T T P+I +YQ+     ++ A   PD VF+ +    E+
Sbjct:    1 LGGPGSGKGTQCARIVEKFGYTHFSTGDLLREEVNSGSERGKNIVAMMEKGELVPNGIILELLRLAMVKQPNTTGFLIDGFPRELEQGLE----FEKELALCELLLYFECSPDTMKARLLKR--GETSGRV-------------------------DDNEETILSRLETFITQTMPVIEHYQEEGKVKKISAEGGPDEVFKKVSRVLEE 178          
BLAST of Adenylate kinase vs. Ensembl Nematostella
Match: EDO38863 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SBK8])

HSP 1 Score: 101.679 bits (252), Expect = 3.493e-26
Identity = 58/212 (27.36%), Postives = 110/212 (51.89%), Query Frame = 1
Query:  142 INAILIGPAGSGKGTQAPKLVERYKICHLATGDMLRAIVSSGSPLGRQVNEIMQQGGLISDEIVCKLIEENLSKQECKNGFILDGFPRTVGQAEKLDQLLEKRNSKINAVVEFNVDDSVLERRITGRLFHLSSGRSYHEEFNPPKQPMIDDITGEKLVRRKDDNVETLKSRLQSYRTDTAPLIGYYQKRNVHYQVKASQKPDRVFEDILNFF 777
            +  I +G  G+GKGT    +V++Y  CHL+ GD+LR  V+ G+  G+ + E+M++G L+  EI   L+++ + + +   GF++DGFPR + Q        E++ +  + V+     + V++ R+  R    +SGR                          DDN+ET+K R  ++   T P++ +Y+K++  +++ AS+  + V+  I + F
Sbjct:    2 VYIITLGGPGAGKGTICDSVVKKYNYCHLSAGDLLREEVTRGNERGQMITEMMREGKLVPKEITIGLLQDAMREHKDMPGFLIDGFPRDIDQG----ITFEEQVTDSDFVLYLECTEEVMQERLLKRA--ETSGRP-------------------------DDNIETIKKRFVTFLEKTVPVVEHYEKQSKAHRIDASRPLEEVYNAISSLF 182          
BLAST of Adenylate kinase vs. Ensembl Nematostella
Match: EDO36160 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SJH0])

HSP 1 Score: 90.1225 bits (222), Expect = 7.370e-22
Identity = 63/221 (28.51%), Postives = 106/221 (47.96%), Query Frame = 1
Query:  124 SESKQNINAILIGPAGSGKGTQAPKLVERYKICHLATGDMLRAIVSSGSPLGRQVNEIMQQGGLISDEIVCKLIEENLSKQECKNGFILDGFPRTVGQAEKLDQLLEKRNSKIN--AVVEFNVDDSVLERRITGRLFHLSSGRSYHEEFNPPKQPMIDDITGEKLVRRKDDNVETLKSRLQSYRTDTAPLIGYYQKRNVHYQVKASQKPDRVFEDILNFFE 780
            S SK  +  +L GP G+GKGTQ  ++V+ Y   HL+ G++LR    SGS  G  +   M +G ++   I   L+++ ++K + +  F++DGFPR     + L     + N K++  AV+ F   + +   RI  R    SSGR                          DDN+E+L+ R  ++   T P+I +Y+++ +   +  +  PD VF  +   FE
Sbjct:    3 SASKPVVIFVLGGP-GAGKGTQCERIVKEYGYVHLSAGELLREERRSGSKDGDLIENCMTEGKIVPVAITVSLLQKAMAKSDVQK-FLIDGFPRN---EDNLQGWESRMNDKVDVKAVLFFECPEDICIGRIMSR--GQSSGRP-------------------------DDNIESLRKRFHTHENSTMPIIEHYRRQGLVKPISGAPTPDEVFLQVKRVFE 191          
BLAST of Adenylate kinase vs. Ensembl Medaka
Match: ak2 (adenylate kinase 2 [Source:NCBI gene;Acc:101169712])

HSP 1 Score: 290.426 bits (742), Expect = 1.325e-98
Identity = 130/222 (58.56%), Postives = 169/222 (76.13%), Query Frame = 1
Query:  121 VSESKQNINAILIGPAGSGKGTQAPKLVERYKICHLATGDMLRAIVSSGSPLGRQVNEIMQQGGLISDEIVCKLIEENLSKQECKNGFILDGFPRTVGQAEKLDQLLEKRNSKINAVVEFNVDDSVLERRITGRLFHLSSGRSYHEEFNPPKQPMIDDITGEKLVRRKDDNVETLKSRLQSYRTDTAPLIGYYQKRNVHYQVKASQKPDRVFEDILNFFEKS 786
            +++  + I AIL+GP G+GKGTQAP+L E+Y +CHLATGDMLRA+V+SGS LG+++ + M  G L+SDE+V +LIE+NL    CKNGF+LDGFPRTV QAE LD LL+KR  K+++V+EF+VDDS+L RRI GRL H  SGRSYHEEFNPPK+PM DD+TGE L+RR DDN  TL+SRL +Y   TAPL+ YY  R +H  + A+Q P+ V   I+  F  +
Sbjct:   11 IADVHEGIRAILLGPPGAGKGTQAPRLAEKYCVCHLATGDMLRAMVASGSELGKRLKQTMDSGKLVSDEMVVELIEKNLDTAACKNGFLLDGFPRTVKQAEMLDDLLDKRQEKLDSVIEFSVDDSLLVRRICGRLIHQPSGRSYHEEFNPPKEPMKDDVTGEPLIRRSDDNETTLRSRLDAYHRQTAPLVQYYSARGIHTAIDAAQSPNVVLASIMAAFSAA 232          
BLAST of Adenylate kinase vs. Ensembl Medaka
Match: ak3 (adenylate kinase 3 [Source:NCBI gene;Acc:101160331])

HSP 1 Score: 164.081 bits (414), Expect = 2.402e-49
Identity = 80/195 (41.03%), Postives = 126/195 (64.62%), Query Frame = 1
Query:  130 SKQNINAILIGPAGSGKGTQAPKLVERYKICHLATGDMLRAIVSSGSPLGRQVNEIMQQGGLISDEIVCKLIEENLSKQECKNGFILDGFPRTVGQAEKLDQLLEKRNSKINAVVEFNVDDSVLERRITGRLFHLSSGRSYHEEFNPPKQPMIDDITGEKLVRRKDDNVETLKSRLQSYRTDTAPLIGYYQKRNV 714
            S + + A+++GP GSGKGT + ++V+ + + H+++GD+LRA +   + LG  V   M QG L+ D ++ +LI ++L   E  + ++LDGFPRTV QAE LDQ        ++ V+  NV    ++ R+T R  H+SSGR Y+ +FNPPK P  DD+TGE LV+R DD  +T+  RL++Y T T P++ +Y+ + V
Sbjct:    4 STRILRAVIMGPPGSGKGTVSARIVKSFGVKHISSGDILRANIKQQTELGLLVRSCMDQGQLVPDGLMSRLILKDLKSMEHIS-WLLDGFPRTVSQAEALDQAY-----TLDTVINLNVPFQTIKERLTSRWTHISSGRVYNTDFNPPKVPGFDDVTGEPLVQRDDDKPDTVTQRLKAYETQTQPVLEFYRSKGV 192          
BLAST of Adenylate kinase vs. Ensembl Medaka
Match: ak4 (adenylate kinase 4 [Source:NCBI gene;Acc:101175146])

HSP 1 Score: 126.716 bits (317), Expect = 5.118e-35
Identity = 64/197 (32.49%), Postives = 115/197 (58.38%), Query Frame = 1
Query:  148 AILIGPAGSGKGTQAPKLVERYKICHLATGDMLRAIVSSGSPLGRQVNEIMQQGGLISDEIVCKLIEENLSKQECKNGFILDGFPRTVGQAEKLDQLLEKRNSKINAVVEFNVDDSVLERRITGRLFHLSSGRSYHEEFNPPKQPMIDDITGEKLVRRKDDNVETLKSRLQSYRTDTAPLIGYYQKRNVHYQVKASQ 738
            A ++GP GSGKGT + ++ + + + ++++GD LRA + + +  G Q+   +++G  + D +V  L+   L +Q   + ++LDGFPRT+ QA  L+ + +     ++ V+  N+    L+ R++ R  H +SGR Y+  FNPP+    DDITGE L++  DD  E L SRL+ Y+    P+I  Y+ + + +    ++
Sbjct:    7 AAILGPPGSGKGTISKRIAQSFGLQYVSSGDYLRAGIPANTEAGVQMKTYIERGLSVPDHVVTGLVLPKL-EQLSSHSWLLDGFPRTLAQALVLNNVYQ-----LDLVISLNIPYETLKDRLSDRWIHPASGRVYNMSFNPPRVQGKDDITGEPLIQHDDDKPEALMSRLRQYKEVAKPVIDLYKTQGILHSFSGTE 197          
BLAST of Adenylate kinase vs. Ensembl Medaka
Match: ak1 (adenylate kinase 1 [Source:NCBI gene;Acc:101156342])

HSP 1 Score: 107.071 bits (266), Expect = 9.887e-28
Identity = 67/203 (33.00%), Postives = 106/203 (52.22%), Query Frame = 1
Query:  151 ILIGPAGSGKGTQAPKLVERYKICHLATGDMLRAIVSSGSPLGRQVNEIMQQGGLISDEIVCKLIEENL-SKQECKNGFILDGFPRTVGQAEKLDQLLEKRNSKINAVVEFNVDDSVLERRITGRLFHLSSGRSYHEEFNPPKQPMIDDITGEKLVRRKDDNVETLKSRLQSYRTDTAPLIGYYQKRNVHYQVKASQKPDRVF 756
             ++G  GSGKGTQ  ++V +Y   HL++GD+LRA V+SGS  G+Q+  IMQ+G L+  + V  +I++ + +K +   GF++DG+PR V Q E+     EK+  K   ++  +     + +R+  R    +SGRS                         DDN ET+K RL  Y   T P+I +Y+ R +  +V +    D VF
Sbjct:   12 FVVGGPGSGKGTQCERIVAKYGYTHLSSGDLLRAEVASGSDRGKQLQAIMQKGELVPLDTVLDMIKDAMIAKADVSKGFLIDGYPREVKQGEE----FEKKIGKPCLLLYVDAKSETMIKRLLKR--GETSGRS-------------------------DDNEETIKKRLDLYYKATEPVIAFYESRGIVKKVDSELPVDEVF 183          
BLAST of Adenylate kinase vs. Ensembl Medaka
Match: ak1 (adenylate kinase 1 [Source:NCBI gene;Acc:101156342])

HSP 1 Score: 107.071 bits (266), Expect = 1.003e-27
Identity = 67/203 (33.00%), Postives = 106/203 (52.22%), Query Frame = 1
Query:  151 ILIGPAGSGKGTQAPKLVERYKICHLATGDMLRAIVSSGSPLGRQVNEIMQQGGLISDEIVCKLIEENL-SKQECKNGFILDGFPRTVGQAEKLDQLLEKRNSKINAVVEFNVDDSVLERRITGRLFHLSSGRSYHEEFNPPKQPMIDDITGEKLVRRKDDNVETLKSRLQSYRTDTAPLIGYYQKRNVHYQVKASQKPDRVF 756
             ++G  GSGKGTQ  ++V +Y   HL++GD+LRA V+SGS  G+Q+  IMQ+G L+  + V  +I++ + +K +   GF++DG+PR V Q E+     EK+  K   ++  +     + +R+  R    +SGRS                         DDN ET+K RL  Y   T P+I +Y+ R +  +V +    D VF
Sbjct:   18 FVVGGPGSGKGTQCERIVAKYGYTHLSSGDLLRAEVASGSDRGKQLQAIMQKGELVPLDTVLDMIKDAMIAKADVSKGFLIDGYPREVKQGEE----FEKKIGKPCLLLYVDAKSETMIKRLLKR--GETSGRS-------------------------DDNEETIKKRLDLYYKATEPVIAFYESRGIVKKVDSELPVDEVF 189          
BLAST of Adenylate kinase vs. Planmine SMEST
Match: SMESG000037481.1 (SMESG000037481.1)

HSP 1 Score: 368.237 bits (944), Expect = 1.378e-129
Identity = 166/225 (73.78%), Postives = 202/225 (89.78%), Query Frame = 1
Query:  106 MGNFFVSESKQNINAILIGPAGSGKGTQAPKLVERYKICHLATGDMLRAIVSSGSPLGRQVNEIMQQGGLISDEIVCKLIEENLSKQECKNGFILDGFPRTVGQAEKLDQLLEKRNSKINAVVEFNVDDSVLERRITGRLFHLSSGRSYHEEFNPPKQPMIDDITGEKLVRRKDDNVETLKSRLQSYRTDTAPLIGYYQKRNVHYQVKASQKPDRVFEDILNFFE 780
            MGN F+S+ K ++NAIL+GP+GSGKGTQAPKL E++KICHL+TGDMLRAIVSSGSPLGRQ+NEIMQ+GGLISDEIVCKLI ENL+   C+NGF+LDGFPRTVGQAEKLD LLEKRNS I+ V+E + +D +LERRI+GRLFH++SGRSYHEEF PPKQPMIDDITGEKL+RRKDDN++TLKS L+SYRT+  PL+ YY+KRN++++V+A+Q PD+VF DIL  FE
Sbjct:    1 MGNLFISQQKSSVNAILLGPSGSGKGTQAPKLAEKFKICHLSTGDMLRAIVSSGSPLGRQINEIMQKGGLISDEIVCKLISENLNHPNCRNGFVLDGFPRTVGQAEKLDALLEKRNSHIDGVIELSAEDHILERRISGRLFHITSGRSYHEEFYPPKQPMIDDITGEKLIRRKDDNLDTLKSLLRSYRTEMEPLVCYYEKRNLYHRVEAAQPPDKVFHDILKIFE 225          
BLAST of Adenylate kinase vs. Planmine SMEST
Match: SMESG000047137.1 (SMESG000047137.1)

HSP 1 Score: 171.785 bits (434), Expect = 9.565e-54
Identity = 106/184 (57.61%), Postives = 113/184 (61.41%), Query Frame = 1
Query:  241 MLRAIVSSGSPLGRQVNEIMQQGGLISDEIVCKLIEENLSKQECKNGFILDGFPRTVGQAEKLDQLLEKRNSKINAVVEFNVDDSVLERRITGRLFHLSSGRSYHEEFNPPKQPMIDDITGEKLVRRKDDNVETLKSRLQSYRTDTAPLIGYYQKRNVHYQVKASQKPDRVFEDILNFFEKSRK 792
            MLRAIVSSGSPLGRQVNEIMQQGGLISDEIV            CK                    L+E+  SK      F +D            F  + G++             + ITGEKLVRRKDDNVETLKSRLQSYRTDTAPLIGYYQKRNVHYQVKASQKPDRVFEDIL FFEKSRK
Sbjct:    1 MLRAIVSSGSPLGRQVNEIMQQGGLISDEIV------------CK--------------------LIEENLSKQECKNGFILDG-----------FPRTVGQA-------------EKITGEKLVRRKDDNVETLKSRLQSYRTDTAPLIGYYQKRNVHYQVKASQKPDRVFEDILKFFEKSRK 128          
BLAST of Adenylate kinase vs. Planmine SMEST
Match: SMESG000061897.1 (SMESG000061897.1)

HSP 1 Score: 135.961 bits (341), Expect = 1.527e-38
Identity = 76/233 (32.62%), Postives = 131/233 (56.22%), Query Frame = 1
Query:  115 FFVSESKQNINAILIGPAGSGKGTQAPKLVERYKICHLATGDMLRAIVSSGSPLGRQVNEIMQQGGLISDEIVCKLIEENLSKQECKNGFILDGFPRTVGQAEKLDQLLEKRNSKINAVVEFNVDDSVLERRITGRLFHLSSGRSYHEEFNPPKQPMIDDITGEKLVRRKDDNVETLKSRLQSYRTDTAPLIGYYQKRNVHYQVKASQKPDRVFEDILNFFEKSRK*ISFERF 813
             F S S  +   ++IG  GSGKGT + ++ + + I ++++GD+LR  V++ + LG   ++ M  G L+ D ++  LI   + K + +N  ++DG+PRTV QA+ LD     +   IN V+  ++   V+  R+  R  HL+SGR YH EFNPP+   +DDITGE L +R DD   T+  RL++Y++   P++ +Y+ + V       +  + ++  +  F     K I F ++
Sbjct:    1 MFRSRSLNSFKCLIIGAPGSGKGTISSRINKDFSIKYISSGDLLRNNVANKTELGIHASKFMNDGKLVPDSLITDLILSEIKKYKNEN-LLIDGYPRTVEQAKVLD-----KEETINCVINLDIPFQVIIDRLKKRWTHLASGRIYHLEFNPPRISGLDDITGEPLEQRDDDKPATIALRLENYQSLADPVLYHYRLQGVVTDF-VGKYSNEIWPKVHQFLSSKLKPIQFTQY 226          
BLAST of Adenylate kinase vs. Planmine SMEST
Match: SMESG000060686.1 (SMESG000060686.1)

HSP 1 Score: 112.464 bits (280), Expect = 7.869e-30
Identity = 69/211 (32.70%), Postives = 114/211 (54.03%), Query Frame = 1
Query:  154 LIGPAGSGKGTQAPKLVERYKICHLATGDMLRAIVSSGSPLGRQVNEIMQQGGLISDEIVCKLIEENLSKQ-ECKNGFILDGFPRTVGQAEKLDQLLEKRNSKINAVVEFNVDDSVLERRITGRLFHLSSGRSYHEEFNPPKQPMIDDITGEKLVRRKDDNVETLKSRLQSYRTDTAPLIGYYQKRNVHYQVKASQKPDRVFEDILNFFEK 783
            ++G  GSGKGTQ  K+V +Y   HL++GD+LR  V SGS  G ++ EIM++G L+S +IV  LI + + K+ +  +GF++DG+PR + Q ++     E        V+ F+V + V+  R+  R    +SGR                          DDN ET+  RL+++   T P+I +Y+K++  +Q+ AS   D +FE + +  +K
Sbjct:   21 VLGGPGSGKGTQCEKIVNKYGFNHLSSGDLLREEVESGSERGNKLKEIMEKGELVSLDIVLDLIRDAMVKKIDHSHGFLIDGYPRELEQGKR----FENEIIPCECVIAFSVSEDVMRARLLKR--GETSGRV-------------------------DDNAETIIKRLKTFNELTKPVIDHYEKQHKAHQIDASGTIDEIFEKVTHVIDK 200          
BLAST of Adenylate kinase vs. Planmine SMEST
Match: SMESG000027219.1 (SMESG000027219.1)

HSP 1 Score: 88.5817 bits (218), Expect = 1.589e-19
Identity = 58/204 (28.43%), Postives = 102/204 (50.00%), Query Frame = 1
Query:  151 ILIGPAGSGKGTQAPKLVERYKICHLATGDMLRAIVSSGSPLGRQVNEIMQQGGLISDEIVCKLIEENLSKQECKN-GFILDGFPRTVGQAEKLDQLLEKRNSKINAVVEFNVDDSVLERRITGRLFHLSSGRSYHEEFNPPKQPMIDDITGEKLVRRKDDNVETLKSRLQSYRTDTAPLIGYYQKRNVHYQVKASQKPDRVFE 759
            IL+GP+GSGK T A  + ++Y I  +  GD++R  ++  +  G  +   +++   + D ++ +LIEE L+   C   G++L G+P +V QAE    LL+    + N V    V   V   R+  R     +G  YH  +NPP    ++     ++ +   D+V+ +K +L  Y +    L  YY+    H  + A+Q+   +FE
Sbjct:  272 ILLGPSGSGKSTIANLICKKYSIMKVNCGDLIREAIADENKHGLAMRSYVEKNLPVPDFVLIQLIEERLTNLCCSTYGWLLYGYPLSVKQAE----LLDCTKLEPNRVFFLEVPSFVSLERLCERRLDPVTGDQYHLSYNPP----VNQSAFNRMSKHPKDDVKVIKHKLAVYNSTVIELKEYYKD---HVVIDANQELHNIFE 464          
The following BLAST results are available for this feature:
BLAST of Adenylate kinase vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5
Match NameE-valueIdentityDescription
AK25.023e-10061.82adenylate kinase 2 [Source:HGNC Symbol;Acc:HGNC:36... [more]
AK25.982e-10061.82adenylate kinase 2 [Source:HGNC Symbol;Acc:HGNC:36... [more]
AK27.593e-10061.82adenylate kinase 2 [Source:HGNC Symbol;Acc:HGNC:36... [more]
AK21.330e-7150.91adenylate kinase 2 [Source:HGNC Symbol;Acc:HGNC:36... [more]
AK22.394e-7150.91adenylate kinase 2 [Source:HGNC Symbol;Acc:HGNC:36... [more]
back to top
BLAST of Adenylate kinase vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 5
Match NameE-valueIdentityDescription
let-7545.634e-9159.26Adenylate kinase [Source:UniProtKB/Swiss-Prot;Acc... [more]
let-7545.634e-9159.26Adenylate kinase [Source:UniProtKB/Swiss-Prot;Acc... [more]
F38B2.44.950e-3232.39Adenylate kinase isoenzyme 1 [Source:UniProtKB/Sw... [more]
ZK673.21.172e-2833.68Probable adenylate kinase isoenzyme ZK673.2 [Sour... [more]
C29F7.39.176e-2227.65UMP-CMP kinase 1 [Source:UniProtKB/Swiss-Prot;Acc... [more]
back to top
BLAST of Adenylate kinase vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Adk27.762e-9760.19gene:FBgn0283494 transcript:FBtr0072163[more]
Adk32.889e-3635.86gene:FBgn0042094 transcript:FBtr0082331[more]
Adk32.889e-3635.86gene:FBgn0042094 transcript:FBtr0339379[more]
Adk32.889e-3635.86gene:FBgn0042094 transcript:FBtr0082330[more]
Adk32.889e-3635.86gene:FBgn0042094 transcript:FBtr0339378[more]
back to top
BLAST of Adenylate kinase vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
ak27.380e-9860.36adenylate kinase 2 [Source:NCBI gene;Acc:321793][more]
ak21.297e-9760.36adenylate kinase 2 [Source:NCBI gene;Acc:321793][more]
ak37.575e-4836.79adenylate kinase 3 [Source:ZFIN;Acc:ZDB-GENE-04042... [more]
ak43.054e-3833.01adenylate kinase 4 [Source:ZFIN;Acc:ZDB-GENE-04042... [more]
ak43.054e-3833.01adenylate kinase 4 [Source:ZFIN;Acc:ZDB-GENE-04042... [more]
back to top
BLAST of Adenylate kinase vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5
Match NameE-valueIdentityDescription
ak28.864e-10263.30adenylate kinase 2 [Source:NCBI gene;Acc:448011][more]
ak28.961e-10263.30adenylate kinase 2 [Source:NCBI gene;Acc:448011][more]
ak24.663e-10163.13adenylate kinase 2 [Source:NCBI gene;Acc:448011][more]
ak38.166e-4937.91adenylate kinase 3 [Source:NCBI gene;Acc:100170447... [more]
ak31.097e-4842.02adenylate kinase 3 [Source:NCBI gene;Acc:100170447... [more]
back to top
BLAST of Adenylate kinase vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Ak28.067e-10160.35adenylate kinase 2 [Source:MGI Symbol;Acc:MGI:8797... [more]
Ak21.193e-10060.35adenylate kinase 2 [Source:MGI Symbol;Acc:MGI:8797... [more]
Ak34.737e-4736.62adenylate kinase 3 [Source:MGI Symbol;Acc:MGI:1860... [more]
Ak42.937e-4233.49adenylate kinase 4 [Source:MGI Symbol;Acc:MGI:8797... [more]
Ak42.937e-4233.49adenylate kinase 4 [Source:MGI Symbol;Acc:MGI:8797... [more]
back to top
BLAST of Adenylate kinase vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|Q8AVD3|KAD2_XENLA2.591e-10263.59Adenylate kinase 2, mitochondrial OS=Xenopus laevi... [more]
sp|Q28F55|KAD2_XENTR5.638e-10163.30Adenylate kinase 2, mitochondrial OS=Xenopus tropi... [more]
sp|P08166|KAD2_BOVIN8.188e-10060.81Adenylate kinase 2, mitochondrial OS=Bos taurus OX... [more]
sp|Q9WTP6|KAD2_MOUSE8.348e-10060.35Adenylate kinase 2, mitochondrial OS=Mus musculus ... [more]
sp|B5XCA1|KAD2_SALSA2.133e-9962.56Adenylate kinase 2, mitochondrial OS=Salmo salar O... [more]
back to top
BLAST of Adenylate kinase vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
A0A2B4RS523.078e-10162.27Adenylate kinase OS=Stylophora pistillata OX=50429... [more]
A0A3M6TCQ43.706e-10162.56Adenylate kinase OS=Pocillopora damicornis OX=4673... [more]
A0A310UE254.129e-10063.59Adenylate kinase 2, mitochondrial OS=Xenopus laevi... [more]
C3Y4K45.780e-10063.18Adenylate kinase OS=Branchiostoma floridae OX=7739... [more]
T1G1C38.243e-10062.83Adenylate kinase OS=Helobdella robusta OX=6412 GN=... [more]
back to top
BLAST of Adenylate kinase vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
ak28.308e-9861.26adenylate kinase 2 [Source:NCBI gene;Acc:103022510... [more]
ak21.444e-9761.26adenylate kinase 2 [Source:NCBI gene;Acc:103022510... [more]
ak36.082e-4935.85adenylate kinase 3 [Source:NCBI gene;Acc:103033473... [more]
ak43.510e-3932.09adenylate kinase 4 [Source:NCBI gene;Acc:103040221... [more]
ak41.227e-3833.01adenylate kinase 4 [Source:NCBI gene;Acc:103040221... [more]
back to top
BLAST of Adenylate kinase vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 3
Match NameE-valueIdentityDescription
ak21.933e-3451.82adenylate kinase 2 [Source:NCBI gene;Acc:321793][more]
ak5l3.652e-1627.05adenylate kinase 5, like [Source:ZFIN;Acc:ZDB-GENE... [more]
spef25.761e-940.51sperm flagellar 2 [Source:NCBI gene;Acc:553375][more]
back to top
BLAST of Adenylate kinase vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 3
Match NameE-valueIdentityDescription
ADK17.678e-8452.97Adenylate kinase, required for purine metabolism; ... [more]
ADK23.509e-4739.51Mitochondrial adenylate kinase; catalyzes the reve... [more]
URA62.130e-2027.75Uridylate kinase; catalyzes the seventh enzymatic ... [more]
back to top
BLAST of Adenylate kinase vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 5
Match NameE-valueIdentityDescription
EDO305502.491e-8957.14Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO425835.641e-4443.01Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO388645.307e-2730.62Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO388633.493e-2627.36Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO361607.370e-2228.51Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
back to top
BLAST of Adenylate kinase vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5
Match NameE-valueIdentityDescription
ak21.325e-9858.56adenylate kinase 2 [Source:NCBI gene;Acc:101169712... [more]
ak32.402e-4941.03adenylate kinase 3 [Source:NCBI gene;Acc:101160331... [more]
ak45.118e-3532.49adenylate kinase 4 [Source:NCBI gene;Acc:101175146... [more]
ak19.887e-2833.00adenylate kinase 1 [Source:NCBI gene;Acc:101156342... [more]
ak11.003e-2733.00adenylate kinase 1 [Source:NCBI gene;Acc:101156342... [more]
back to top
BLAST of Adenylate kinase vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5
Match NameE-valueIdentityDescription
SMESG000037481.11.378e-12973.78SMESG000037481.1[more]
SMESG000047137.19.565e-5457.61SMESG000047137.1[more]
SMESG000061897.11.527e-3832.62SMESG000061897.1[more]
SMESG000060686.17.869e-3032.70SMESG000060686.1[more]
SMESG000027219.11.589e-1928.43SMESG000027219.1[more]
back to top
Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30013913 ID=SMED30013913|Name=Adenylate kinase|organism=Schmidtea mediterranea sexual|type=transcript|length=884bp
GAATTTTTCTTTGAAAATTTTATAATATTTAATTGCATTTATTTAATTTG
TAATATTATTACGTAATTTTATATACAAATTTAAACTTTATAACTTTTTT
TATTAATGGGAAACTTCTTTGTCAGTGAATCGAAACAGAACATAAATGCT
ATTTTAATCGGCCCTGCTGGTTCAGGGAAAGGAACACAAGCTCCAAAATT
AGTTGAACGATATAAAATCTGTCATTTAGCAACAGGTGATATGTTGAGAG
CAATAGTTTCATCGGGATCGCCTCTAGGTAGACAAGTAAATGAGATTATG
CAACAAGGTGGATTAATATCCGATGAAATTGTTTGTAAATTAATTGAAGA
AAATCTTAGCAAGCAAGAATGCAAAAATGGTTTTATACTTGATGGATTTC
CGAGAACTGTTGGACAAGCAGAAAAGCTTGATCAATTACTGGAAAAACGT
AACTCAAAAATAAATGCAGTGGTTGAATTTAACGTAGATGACAGCGTTCT
TGAACGGCGGATCACTGGCAGACTGTTTCACCTTTCAAGCGGGCGATCCT
ACCATGAAGAATTTAATCCGCCCAAGCAGCCAATGATTGATGATATTACC
GGAGAAAAGCTTGTTAGAAGGAAAGATGATAATGTTGAAACATTAAAATC
ACGCTTGCAATCGTACCGCACTGATACAGCTCCGTTAATTGGATATTATC
AGAAAAGGAATGTCCATTATCAAGTTAAAGCATCTCAAAAGCCCGATAGA
GTTTTCGAAGATATTTTAAATTTTTTTGAGAAATCGCGAAAATAAATTTC
CTTTGAAAGGTTTCATTCCAGGAATTTAGAAATATATTTAGTAGTTAGCT
TTACAATAAATATTTTGGAATTTTTAAAAAAAAA
back to top

protein sequence of SMED30013913-orf-1

>SMED30013913-orf-1 ID=SMED30013913-orf-1|Name=SMED30013913-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=230bp
MGNFFVSESKQNINAILIGPAGSGKGTQAPKLVERYKICHLATGDMLRAI
VSSGSPLGRQVNEIMQQGGLISDEIVCKLIEENLSKQECKNGFILDGFPR
TVGQAEKLDQLLEKRNSKINAVVEFNVDDSVLERRITGRLFHLSSGRSYH
EEFNPPKQPMIDDITGEKLVRRKDDNVETLKSRLQSYRTDTAPLIGYYQK
RNVHYQVKASQKPDRVFEDILNFFEKSRK*
back to top
Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: biological process
TermDefinition
GO:0046940nucleoside monophosphate phosphorylation
GO:0006139nucleobase-containing compound metabolic process
GO:0006172ADP biosynthetic process
GO:0016310phosphorylation
GO:0046033AMP metabolic process
GO:0046034ATP metabolic process
GO:0046939nucleotide phosphorylation
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000026gut
PLANA:0000070intestinal phagocyte
Vocabulary: INTERPRO
TermDefinition
IPR006259Adenyl_kin_sub
IPR033690Adenylat_kinase_CS
IPR000850Adenylat/UMP-CMP_kin
IPR027417P-loop_NTPase
IPR007862Adenylate_kinase_lid-dom
Vocabulary: molecular function
TermDefinition
GO:0005524ATP binding
GO:0019205nucleobase-containing compound kinase activity
GO:0004017adenylate kinase activity
GO:0000166nucleotide binding
GO:0016301kinase activity
GO:0016740transferase activity
GO:0016776phosphotransferase activity, phosphate group as acceptor
Vocabulary: cellular component
TermDefinition
GO:0005737cytoplasm
GO:0005739mitochondrion
GO:0005758mitochondrial intermembrane space
GO:0005829cytosol
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
NoneNo IPR availableCOILSCoilCoilcoord: 170..190
NoneNo IPR availableGENE3DG3DSA:3.40.50.300coord: 6..229
e-value: 2.8E-83
score: 281.0
NoneNo IPR availablePFAMPF00406ADKcoord: 17..202
e-value: 1.5E-57
score: 194.2
NoneNo IPR availablePANTHERPTHR23359:SF170ADENYLATE KINASE 2, MITOCHONDRIALcoord: 10..227
IPR000850Adenylate kinase/UMP-CMP kinasePRINTSPR00094ADENYLTKNASEcoord: 44..58
score: 55.48
coord: 172..187
score: 51.06
coord: 189..203
score: 36.72
coord: 93..109
score: 62.31
coord: 16..29
score: 64.41
IPR000850Adenylate kinase/UMP-CMP kinasePANTHERPTHR23359NUCLEOTIDE KINASEcoord: 10..227
IPR000850Adenylate kinase/UMP-CMP kinaseCDDcd01428ADKcoord: 14..216
e-value: 1.05448E-87
score: 255.624
IPR007862Adenylate kinase, active site lid domainPFAMPF05191ADK_lidcoord: 139..174
e-value: 4.5E-14
score: 52.1
IPR006259Adenylate kinase subfamilyTIGRFAMTIGR01351TIGR01351coord: 15..224
e-value: 1.3E-74
score: 248.4
IPR033690Adenylate kinase, conserved sitePROSITEPS00113ADENYLATE_KINASEcoord: 93..104
IPR027417P-loop containing nucleoside triphosphate hydrolaseSUPERFAMILYSSF52540P-loop containing nucleoside triphosphate hydrolasescoord: 15..226