tud-1

Overview


Name	tud-1 (AHC00376.1)
Smed ID	SMED30013909
Length (bp)	2414

Neoblast Clusters

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Overview

Single cell RNA-seq of pluripotent neoblasts and its early progenies

We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)

Explore this single cell expression dataset with our NB Cluster Shiny App

Neoblast Population

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.

Expression of tud-1 (SMED30013909) t-SNE clustered cells

Violin plots show distribution of expression levels for tud-1 (SMED30013909) in cells (dots) of each of the 12 neoblast clusters.

Sub-lethal Irradiated Surviving X1 and X2 Cell Population

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of tud-1 (SMED30013909) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for tud-1 (SMED30013909) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

Expression Details

tud-1 ( tud-1 ) is expressed during Stage 2, Stage 3, Stage 4, Stage 5, Stage 6, Stage 7 and Stage 8 in the neoblast and blastomere

Click to see image symbols and abbreviations


Abbreviation or symbol	Definition
O	oral hemisphere
A	aboral hemisphere
D	dorsal
V	ventral
L	lateral
black arrowhead	embryonic pharynx
red arrowhead	definitive pharynx
black arrows	primitive gut
yellow arrows	primitive ectoderm cells
cyan arrows	brain
cyan arrowheads	nerve cords
blue arrowheads	eye progenitors (trail cells)
purple arrowheads	eyes
scale bar	100 µm

piwi-1+ blastomeres co-express the adult asexual neoblast enriched gene tud-1.
SPIM reconstructed S4 embryo costained with piwi-1 (red) and tud-1 (green). piwi-1+ blastomeres co-express the nuage factor tud-1, and virtually all tud-1+ cells co-express piwi-1.

piwi-1+ blastomeres co-express the adult asexual neoblast enriched gene tud-1.
SPIM reconstructed S5 embryo costained with piwi-1 (red) and tud-1 (green). piwi-1+ blastomeres co-express the nuage factor tud-1, and virtually all tud-1+ cells co-express piwi-1.

piwi-1+ blastomeres co-express the adult asexual neoblast enriched gene tud-1.
SPIM reconstructed S3 embryo costained with piwi-1 (red) and tud-1 (green). piwi-1+ blastomeres co-express the nuage factor tud-1, and virtually all tud-1+ cells co-express piwi-1.

Anatomical Expression

PAGE et. al., 2020

SMED30013909

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE

PAGE Curations: 47

Expressed In	Reference Transcript	Gene Models	Published Transcript	Transcriptome	Publication
X2 cell	SMED30013909	h1SMcG0014127	SmedASXL_006995	SmedAsxl_ww_GCZZ01	PMID:26114597 Zhu et al., 2015
X1 cell	SMED30013909	h1SMcG0014127	SmedASXL_006995	SmedAsxl_ww_GCZZ01	PMID:26114597 Zhu et al., 2015
pharynx	SMED30013909	h1SMcG0014127	dd_Smed_v4_1582_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
nervous system	SMED30013909	h1SMcG0014127	dd_Smed_v4_1582_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
epidermis	SMED30013909	h1SMcG0014127	dd_Smed_v4_1582_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
cephalic ganglia	SMED30013909	h1SMcG0014127	dd_Smed_v4_1582_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
muscle cell	SMED30013909	h1SMcG0014127	dd_Smed_v4_1582_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
neoblast	SMED30013909	h1SMcG0014127	dd_Smed_v4_1582_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
parenchymal cell	SMED30013909	h1SMcG0014127	dd_Smed_v4_1582_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
non-ciliated neuron	SMED30013909	h1SMcG0014127	dd_Smed_v4_1582_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
cilated neuron	SMED30013909	h1SMcG0014127	dd_Smed_v4_1582_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
Smed sexual biotype	SMED30013909	h1SMcG0014127	Contig48859	uc_Smed_v2	PMID:29674431 Fincher et al., 2018
Smed sexual biotype	SMED30013909	h1SMcG0014127	Contig48859	newmark_ests	PMID:29674431 Fincher et al., 2018
neoblast	SMED30013909	h1SMcG0014127	tud-1	smed_ncbi_20240424	PMID:28072387 Davies et al., 2017
neoblast	SMED30013909	h1SMcG0014127	tud-1	smed_ncbi_20240424	PMID:28072387 Davies et al., 2017
neoblast	SMED30013909	h1SMcG0014127	tud-1	smed_ncbi_20240424	PMID:28072387 Davies et al., 2017
blastomere	SMED30013909	h1SMcG0014127	tud-1	smed_ncbi_20240424	PMID:28072387 Davies et al., 2017
blastomere	SMED30013909	h1SMcG0014127	tud-1	smed_ncbi_20240424	PMID:28072387 Davies et al., 2017
blastomere	SMED30013909	h1SMcG0014127	tud-1	smed_ncbi_20240424	PMID:28072387 Davies et al., 2017
blastomere	SMED30013909	h1SMcG0014127	tud-1	smed_ncbi_20240424	PMID:28072387 Davies et al., 2017
blastomere	SMED30013909	h1SMcG0014127	tud-1	smed_ncbi_20240424	PMID:28072387 Davies et al., 2017
blastomere	SMED30013909	h1SMcG0014127	tud-1	smed_ncbi_20240424	PMID:28072387 Davies et al., 2017
blastomere	SMED30013909	h1SMcG0014127	tud-1	smed_ncbi_20240424	PMID:28072387 Davies et al., 2017
neoblast	SMED30013909	h1SMcG0014127	KF781126	smed_ncbi_20240424	PMID:28072387 Davies et al., 2017
neoblast	SMED30013909	h1SMcG0014127	KF781126	smed_ncbi_20240424	PMID:28072387 Davies et al., 2017
neoblast	SMED30013909	h1SMcG0014127	KF781126	smed_ncbi_20240424	PMID:28072387 Davies et al., 2017
blastomere	SMED30013909	h1SMcG0014127	KF781126	smed_ncbi_20240424	PMID:28072387 Davies et al., 2017
blastomere	SMED30013909	h1SMcG0014127	KF781126	smed_ncbi_20240424	PMID:28072387 Davies et al., 2017
blastomere	SMED30013909	h1SMcG0014127	KF781126	smed_ncbi_20240424	PMID:28072387 Davies et al., 2017
blastomere	SMED30013909	h1SMcG0014127	KF781126	smed_ncbi_20240424	PMID:28072387 Davies et al., 2017
blastomere	SMED30013909	h1SMcG0014127	KF781126	smed_ncbi_20240424	PMID:28072387 Davies et al., 2017
blastomere	SMED30013909	h1SMcG0014127	KF781126	smed_ncbi_20240424	PMID:28072387 Davies et al., 2017
blastomere	SMED30013909	h1SMcG0014127	KF781126	smed_ncbi_20240424	PMID:28072387 Davies et al., 2017
neoblast	SMED30013909	h1SMcG0014127	SMED30013909	smed_20140614	PMID:28072387 Davies et al., 2017
neoblast	SMED30013909	h1SMcG0014127	SMED30013909	smed_20140614	PMID:28072387 Davies et al., 2017
neoblast	SMED30013909	h1SMcG0014127	SMED30013909	smed_20140614	PMID:28072387 Davies et al., 2017
blastomere	SMED30013909	h1SMcG0014127	SMED30013909	smed_20140614	PMID:28072387 Davies et al., 2017
blastomere	SMED30013909	h1SMcG0014127	SMED30013909	smed_20140614	PMID:28072387 Davies et al., 2017
blastomere	SMED30013909	h1SMcG0014127	SMED30013909	smed_20140614	PMID:28072387 Davies et al., 2017
blastomere	SMED30013909	h1SMcG0014127	SMED30013909	smed_20140614	PMID:28072387 Davies et al., 2017
blastomere	SMED30013909	h1SMcG0014127	SMED30013909	smed_20140614	PMID:28072387 Davies et al., 2017
blastomere	SMED30013909	h1SMcG0014127	SMED30013909	smed_20140614	PMID:28072387 Davies et al., 2017
blastomere	SMED30013909	h1SMcG0014127	SMED30013909	smed_20140614	PMID:28072387 Davies et al., 2017
parenchyma	SMED30013909	h1SMcG0014127	Contig48859	uc_Smed_v2	PMID:27612384 Roberts-Galbraith et al., 2016
parenchyma	SMED30013909	h1SMcG0014127	Contig48859	newmark_ests	PMID:27612384 Roberts-Galbraith et al., 2016
X1 cell	SMED30013909	h1SMcG0014127	isotig12850	be_Smed_v2	PMID:22543868 Onal et al., 2012
neoblast	SMED30013909	h1SMcG0014127	dd_Smed_v6_1582_0	dd_Smed_v6	PMID:29674432 Plass et al., 2018

Note: Hover over icons to view figure legend

Homology

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BLAST of tud-1 vs. Ensembl Zebrafish
Match: tdrd6 (tudor domain containing 6 [Source:ZFIN;Acc:ZDB-GENE-041001-210])

HSP 1 Score: 53.1434 bits (126), Expect = 1.469e-6
Identity = 38/128 (29.69%), Postives = 64/128 (50.00%), Query Frame = 1

Query: 1588 GKSFKVIMSHVVSPINFFIQLDDGEHQLALGDIQEKLNINYNGSPFKSASDVKETQAVIAPFIVSGSDAELFRAYVLEKRKESPQIHVLFIDYGNDEWVNYETLLNTNEELVSKPGFAIHCKLS-LNI 1968
            G   +V +SH  SP +FF+Q    E  +    + EKLN + +      +SD+ E   V A F     D+  +RA V +   E  +I V F+D+GN   ++ + + +  +   S P ++IHC +  LN+
Sbjct: 1234 GLEAEVFISHCNSPCSFFVQFATDEDDIY--SLVEKLNADQSRCRNIDSSDIHEGDLVCAMF---PDDSSWYRAVVRKNTNE--KIDVEFVDFGNTAVISSKNVCHLGQSFASFPRYSIHCSVHKLNV 1354

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Query: 1588 GKSFKVIMSHVVSPINFFIQLDDGEHQLALGDIQEKLNINYNGSPFKSASDVKETQAVIAPFIVSGSDAELFRAYVLEKRKESPQIHVLFIDYGNDEWVNYETLLNTNEELVSKPGFAIHCKLS-LNI 1968
            G   +V +SH  SP +FF+Q    E  +    + EKLN + +      +SD+ E   V A F     D+  +RA V +   E  +I V F+D+GN   ++ + + +  +   S P ++IHC +  LN+
Sbjct: 1234 GLEAEVFISHCNSPCSFFVQFATDEDDIY--SLVEKLNADQSRCRNIDSSDIHEGDLVCAMF---PDDSSWYRAVVRKNTNE--KIDVEFVDFGNTAVISSKNVCHLGQSFASFPRYSIHCSVHKLNV 1354

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BLAST of tud-1 vs. Ensembl Zebrafish
Match: si:ch211-189e2.3 (si:ch211-189e2.3 [Source:ZFIN;Acc:ZDB-GENE-030131-6454])

HSP 1 Score: 51.2174 bits (121), Expect = 5.355e-6
Identity = 58/221 (26.24%), Postives = 99/221 (44.80%), Query Frame = 1

Query: 1540 QKKAYEYAKVSYKDL----IGKSFKVIMSHVVSPINFFIQLDDGEHQLALGDIQEKLNINYNGSPFKSASDVKETQAVIAPFIVSGSDAELFRAYVLEKRKESPQIHVLFIDYGNDEWVNYETLLNTNEELVSKPGFAIHCKLSLNIK--KEAWSH-AIELFNDLAGYTENDQGTFVMQVISVDGDSLVVDLISELKGSLT----AILEKSGTCVKSNEPI 2169
            Q++   Y K++   L    +G    V +SH  SP NFF+QL   E ++    + EKLN           + ++    V A +    +D   +RA V  K K++  + V FID+GN+  +    +   +++ +S P  +I C L    +  K  W+   I  F + AG  EN +     + I  D +  +V L  + +G  T    A  E    C+K+ +P+
Sbjct:  764 QQQVMAYPKLTELPLRTIDVGYVSDVYVSHCNSPSNFFVQLTTDEDEIF--SLIEKLNCTLISDLQVELNLLQSDDLVKAEY---PADGAYYRAVV--KSKKNGMVQVQFIDFGNEVTLLPTKIKQLDKQFLSTPRLSIQCMLEDGKRRGKRDWTQEEIMTFKEAAG--ENGEKKIQCKFIQEDANCWLVSLEHQ-EGWFTVKSDAQSESQVHCIKNTQPL 974

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BLAST of tud-1 vs. Ensembl Zebrafish
Match: si:ch211-189e2.3 (si:ch211-189e2.3 [Source:ZFIN;Acc:ZDB-GENE-030131-6454])

HSP 1 Score: 51.2174 bits (121), Expect = 5.793e-6
Identity = 58/221 (26.24%), Postives = 99/221 (44.80%), Query Frame = 1

Query: 1540 QKKAYEYAKVSYKDL----IGKSFKVIMSHVVSPINFFIQLDDGEHQLALGDIQEKLNINYNGSPFKSASDVKETQAVIAPFIVSGSDAELFRAYVLEKRKESPQIHVLFIDYGNDEWVNYETLLNTNEELVSKPGFAIHCKLSLNIK--KEAWSH-AIELFNDLAGYTENDQGTFVMQVISVDGDSLVVDLISELKGSLT----AILEKSGTCVKSNEPI 2169
            Q++   Y K++   L    +G    V +SH  SP NFF+QL   E ++    + EKLN           + ++    V A +    +D   +RA V  K K++  + V FID+GN+  +    +   +++ +S P  +I C L    +  K  W+   I  F + AG  EN +     + I  D +  +V L  + +G  T    A  E    C+K+ +P+
Sbjct:  764 QQQVMAYPKLTELPLRTIDVGYVSDVYVSHCNSPSNFFVQLTTDEDEIF--SLIEKLNCTLISDLQVELNLLQSDDLVKAEY---PADGAYYRAVV--KSKKNGMVQVQFIDFGNEVTLLPTKIKQLDKQFLSTPRLSIQCMLEDGKRRGKRDWTQEEIMTFKEAAG--ENGEKKIQCKFIQEDANCWLVSLEHQ-EGWFTVKSDAQSESQVHCIKNTQPL 974

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BLAST of tud-1 vs. Ensembl Zebrafish
Match: si:ch211-189e2.3 (si:ch211-189e2.3 [Source:ZFIN;Acc:ZDB-GENE-030131-6454])

HSP 1 Score: 51.2174 bits (121), Expect = 6.045e-6
Identity = 58/221 (26.24%), Postives = 99/221 (44.80%), Query Frame = 1

Query: 1540 QKKAYEYAKVSYKDL----IGKSFKVIMSHVVSPINFFIQLDDGEHQLALGDIQEKLNINYNGSPFKSASDVKETQAVIAPFIVSGSDAELFRAYVLEKRKESPQIHVLFIDYGNDEWVNYETLLNTNEELVSKPGFAIHCKLSLNIK--KEAWSH-AIELFNDLAGYTENDQGTFVMQVISVDGDSLVVDLISELKGSLT----AILEKSGTCVKSNEPI 2169
            Q++   Y K++   L    +G    V +SH  SP NFF+QL   E ++    + EKLN           + ++    V A +    +D   +RA V  K K++  + V FID+GN+  +    +   +++ +S P  +I C L    +  K  W+   I  F + AG  EN +     + I  D +  +V L  + +G  T    A  E    C+K+ +P+
Sbjct:  764 QQQVMAYPKLTELPLRTIDVGYVSDVYVSHCNSPSNFFVQLTTDEDEIF--SLIEKLNCTLISDLQVELNLLQSDDLVKAEY---PADGAYYRAVV--KSKKNGMVQVQFIDFGNEVTLLPTKIKQLDKQFLSTPRLSIQCMLEDGKRRGKRDWTQEEIMTFKEAAG--ENGEKKIQCKFIQEDANCWLVSLEHQ-EGWFTVKSDAQSESQVHCIKNTQPL 974

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BLAST of tud-1 vs. Ensembl Xenopus
Match: ENSXETT00000011761.1 (ring finger protein 17 [Source:NCBI gene;Acc:100490831])

HSP 1 Score: 55.8398 bits (133), Expect = 2.937e-7
Identity = 40/126 (31.75%), Postives = 65/126 (51.59%), Query Frame = 1

Query: 1594 SFKVIMSHVVSPINFFIQLDDGEHQLAL--GDIQEKLNINYNGSPFKSASDVKETQAVIAPFIVSG-SDAELFRAYVLEKRKESPQIHVLFIDYGNDEWVNYETLLNTNEELVSKPGFAIHCKLSL 1962
            +F V++SHV SP +F+IQ+ D  ++ A    +IQE  N           SD+K   AVI    +    D   +RA V+    +  ++ + F+D+G+ + VN  TL +  EE +  P  AI C+L+ 
Sbjct:  394 NFTVVVSHVNSPSDFYIQVADNANEYATFSQEIQEVYNCE--------ESDLKIKHAVIGQVCMKKFKDGYWYRAVVVGFTGQD-EVTIKFVDFGDTDTVNVSTLRDIKEEFLDMPCKAICCRLAF 510

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BLAST of tud-1 vs. TrEMBL
Match: V5W3W8 (Tud-1 OS=Schmidtea mediterranea OX=79327 PE=2 SV=1)

HSP 1 Score: 1488.78 bits (3853), Expect = 0.000e+0
Identity = 769/770 (99.87%), Postives = 770/770 (100.00%), Query Frame = 1

Query:   10 MEATCDVFLTNLPKSINEVVVKNLFSSAGKVLKVKIIDDKRNENQKLCFVGFRTMDEALEAVRIADKSDAFGDPIRASISKKCLDGMEXXXXXXXXXXXXXXYKGTDSFSRKSDSNFKDSEKYPTNNGDFAQVNRLNNVGRGRGIQTKIISGPPSFKTNEIKLNDIKLKTKELIDIEIVDLSRVDIILIRPVKSTENSKIEIADLLSQINSNKSNLMPVDCPKIGDFCLAKWTEDDCYYRAELLDILKDGSFKVTFVDEGTSGDIVTDLKHIPTGALQQYPKQFLKVSIGCSDAKELMSFILQESEGKVIKIYWLGEYCDSVPVVNLFLNEDEIVEKYTQINKVNIRKKFSQTFDDLPVHNLETNSHFSIAPSMYKNRNDFILQMKTFSVSLKQKKCPTVLPIPGDICIYEKRNANGESFLRCVILRRQLFSFDIELIDIGEKIMNVNIDHLYTVEDIHVKDAPCAITCDLDSSINIDGIKLPQDLIDGXXXXXXXXXXXXXXXXXXILPQKKAYEYAKVSYKDLIGKSFKVIMSHVVSPINFFIQLDDGEHQLALGDIQEKLNINYNGSPFKSASDVKETQAVIAPFIVSGSDAELFRAYVLEKRKESPQIHVLFIDYGNDEWVNYETLLNTNEELVSKPGFAIHCKLSLNIKKEAWSHAIELFNDLAGYTENDQGTFVMQVISVDGDSLVVDLISELKGSLTAILEKSGTCVKSNEPICNGGGPQVKLNGVSNDKSQSAILENLSEGELYKKFIELERRLSALEILMK 2319
            MEATCDVFLTNLPKSINEVVVKNLFSSAGKVLKVKIIDDKRNENQKLCFVGFRTMDEALEAVRIADKSDAFGDPIRASISKKCLDGMENNQNRSNNNRNDSSYKGTDSFSRKSDSNFKDSEKYPTNNGDFAQVNRLNNVGRGRGIQTKIISGPPSFKTNEIKLNDIKLKTKELIDIEIVDLSRVDIILIRPVKSTENSKIEIADLLSQINSNKSNLMPVDCPKIGDFCLAKWTEDDCYYRAELLDILKDGSFKVTFVDEGTSGDIVTDLKHIPTGALQQYPKQFLKVSIGCSDAKELMSFILQESEGKVIKIYWLGEYCDSVPVVNLFLNEDEIVEKYTQINKVNIRKKFSQTFDDLPVHNLETNSHFSIAPSMYKNRNDFILQMKTFS+SLKQKKCPTVLPIPGDICIYEKRNANGESFLRCVILRRQLFSFDIELIDIGEKIMNVNIDHLYTVEDIHVKDAPCAITCDLDSSINIDGIKLPQDLIDGVLFNLKKYNKNNKYTVNFILPQKKAYEYAKVSYKDLIGKSFKVIMSHVVSPINFFIQLDDGEHQLALGDIQEKLNINYNGSPFKSASDVKETQAVIAPFIVSGSDAELFRAYVLEKRKESPQIHVLFIDYGNDEWVNYETLLNTNEELVSKPGFAIHCKLSLNIKKEAWSHAIELFNDLAGYTENDQGTFVMQVISVDGDSLVVDLISELKGSLTAILEKSGTCVKSNEPICNGGGPQVKLNGVSNDKSQSAILENLSEGELYKKFIELERRLSALEILMK
Sbjct:    1 MEATCDVFLTNLPKSINEVVVKNLFSSAGKVLKVKIIDDKRNENQKLCFVGFRTMDEALEAVRIADKSDAFGDPIRASISKKCLDGMENNQNRSNNNRNDSSYKGTDSFSRKSDSNFKDSEKYPTNNGDFAQVNRLNNVGRGRGIQTKIISGPPSFKTNEIKLNDIKLKTKELIDIEIVDLSRVDIILIRPVKSTENSKIEIADLLSQINSNKSNLMPVDCPKIGDFCLAKWTEDDCYYRAELLDILKDGSFKVTFVDEGTSGDIVTDLKHIPTGALQQYPKQFLKVSIGCSDAKELMSFILQESEGKVIKIYWLGEYCDSVPVVNLFLNEDEIVEKYTQINKVNIRKKFSQTFDDLPVHNLETNSHFSIAPSMYKNRNDFILQMKTFSISLKQKKCPTVLPIPGDICIYEKRNANGESFLRCVILRRQLFSFDIELIDIGEKIMNVNIDHLYTVEDIHVKDAPCAITCDLDSSINIDGIKLPQDLIDGVLFNLKKYNKNNKYTVNFILPQKKAYEYAKVSYKDLIGKSFKVIMSHVVSPINFFIQLDDGEHQLALGDIQEKLNINYNGSPFKSASDVKETQAVIAPFIVSGSDAELFRAYVLEKRKESPQIHVLFIDYGNDEWVNYETLLNTNEELVSKPGFAIHCKLSLNIKKEAWSHAIELFNDLAGYTENDQGTFVMQVISVDGDSLVVDLISELKGSLTAILEKSGTCVKSNEPICNGGGPQVKLNGVSNDKSQSAILENLSEGELYKKFIELERRLSALEILMK 770

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BLAST of tud-1 vs. TrEMBL
Match: C0L3L0 (Tudor domain containing 1 OS=Schmidtea polychroa OX=50054 GN=oltud-1 PE=2 SV=1)

HSP 1 Score: 1339.32 bits (3465), Expect = 0.000e+0
Identity = 680/770 (88.31%), Postives = 727/770 (94.42%), Query Frame = 1

Query:   10 MEATCDVFLTNLPKSINEVVVKNLFSSAGKVLKVKIIDDKRNENQKLCFVGFRTMDEALEAVRIADKSDAFGDPIRASISKKCLDGMEXXXXXXXXXXXXXXYKGTDSFSRKSDSNFKDSEKYPTNNGDFAQVNRLNNVGRGRGIQTKIISGPPSFKTNEIKLNDIKLKTKELIDIEIVDLSRVDIILIRPVKSTENSKIEIADLLSQINSNKSNLMPVDCPKIGDFCLAKWTEDDCYYRAELLDILKDGSFKVTFVDEGTSGDIVTDLKHIPTGALQQYPKQFLKVSIGCSDAKELMSFILQESEGKVIKIYWLGEYCDSVPVVNLFLNEDEIVEKYTQINKVNIRKKFSQTFDDLPVHNLETNSHFSIAPSMYKNRNDFILQMKTFSVSLKQKKCPTVLPIPGDICIYEKRNANGESFLRCVILRRQLFSFDIELIDIGEKIMNVNIDHLYTVEDIHVKDAPCAITCDLDSSINIDGIKLPQDLIDGXXXXXXXXXXXXXXXXXXILPQKKAYEYAKVSYKDLIGKSFKVIMSHVVSPINFFIQLDDGEHQLALGDIQEKLNINYNGSPFKSASDVKETQAVIAPFIVSGSDAELFRAYVLEKRKESPQIHVLFIDYGNDEWVNYETLLNTNEELVSKPGFAIHCKLSLNIKKEAWSHAIELFNDLAGYTENDQGTFVMQVISVDGDSLVVDLISELKGSLTAILEKSGTCVKSNEPICNGGGPQVKLNGVSNDKSQSAILENLSEGELYKKFIELERRLSALEILMK 2319
            M+ATCDVFLTNLPKSI+EVVVKNLFSSAGKVLKVKIIDDKRNENQKLCFVGFRTMDEALEAVRIAD+SDAFGDPIRASISKKCLDGMENNQNRSNN RNDSS+KG+DSFSRKS+SNFKDSEKYP+NNGDFAQVNRLNNVGRGRGIQ KIISGPPSFKTNEIKLNDIKLKTKEL+DIEIVDLSRVD+ILIRPVK TENSKIEIADLLSQINSN+SNL+PVDCPK+GDF LAKWTEDDCYYRAELLDILK+GSFKVTFVDEGTSGDIVTDLKHIPTGALQQYPKQFLKVSIGCSD KELMSFI+ ESEGKVIKIYWLGEYCDS+PVVNLFLNEDEIVEKY QINK+NIRKK S TFDDLPVHNLET+SHFS  PSMYKN N+FILQMK  S+SL  KKCPTVLPIPGDICIYEKRN+ GESFLR VILRRQLFSFDIELIDIGEKIMNVNID+LYT E+ H+K+APCAITCDLD+S+N+DG +L Q LIDGV+FNLKKY +NNKYTV+F LP+KK YEYAKVSYKD IGKSFKVIMSHVVSPINFFIQLDDG++QLALGDIQEKLNINY+GS FKS  DV  TQAVIAPFIVSG+DAELFRAYVLEKRKESPQIHVLFIDYGNDEWVNYETLLN NEEL++KPGFAIHCKLSLNI+KEAWSHA ELF+DLAGY+ENDQG FVMQVI VDGD+LVVDLISE+KGSLTAILEKSGTCVK NEP CNGG P VKLNGV NDKSQ+AILENLSEGELYKK +ELERRL+ALEI +K
Sbjct:    1 MDATCDVFLTNLPKSISEVVVKNLFSSAGKVLKVKIIDDKRNENQKLCFVGFRTMDEALEAVRIADRSDAFGDPIRASISKKCLDGMENNQNRSNNTRNDSSFKGSDSFSRKSESNFKDSEKYPSNNGDFAQVNRLNNVGRGRGIQNKIISGPPSFKTNEIKLNDIKLKTKELVDIEIVDLSRVDLILIRPVKPTENSKIEIADLLSQINSNQSNLVPVDCPKVGDFYLAKWTEDDCYYRAELLDILKEGSFKVTFVDEGTSGDIVTDLKHIPTGALQQYPKQFLKVSIGCSDVKELMSFIIHESEGKVIKIYWLGEYCDSIPVVNLFLNEDEIVEKYAQINKINIRKKLSHTFDDLPVHNLETSSHFSFVPSMYKNENEFILQMKNSSISLSHKKCPTVLPIPGDICIYEKRNSTGESFLRSVILRRQLFSFDIELIDIGEKIMNVNIDNLYTAEESHLKNAPCAITCDLDNSVNLDGDRLLQVLIDGVIFNLKKYKRNNKYTVSFNLPEKKVYEYAKVSYKDFIGKSFKVIMSHVVSPINFFIQLDDGDNQLALGDIQEKLNINYSGSAFKSVGDVNITQAVIAPFIVSGTDAELFRAYVLEKRKESPQIHVLFIDYGNDEWVNYETLLNVNEELITKPGFAIHCKLSLNIRKEAWSHANELFSDLAGYSENDQGAFVMQVIGVDGDTLVVDLISEMKGSLTAILEKSGTCVKLNEPTCNGGSPAVKLNGVINDKSQTAILENLSEGELYKKVLELERRLNALEISLK 770

[Close]

BLAST of tud-1 vs. TrEMBL
Match: A4V6J8 (Tudor protein (Fragment) OS=Dugesia japonica OX=6161 PE=2 SV=1)

HSP 1 Score: 336.265 bits (861), Expect = 1.195e-105
Identity = 165/247 (66.80%), Postives = 203/247 (82.19%), Query Frame = 1

Query: 1534 LPQKKAYEYAKVSYKDLIGKSFKVIMSHVVSPINFFIQLDDGEHQLALGDIQEKLNINYNGSPFKSASDVKETQAVIAPFIVSGSDAELFRAYVLEKRKESPQIHVLFIDYGNDEWVNYETLLNTNEELVSKPGFAIHCKLSLNIKKEAWSHAIELFNDLAGYTENDQGTFVMQVISVDGDSLVVDLISELKGSLTAILEKSGTCV-KSNEPICNGGGPQVKLNGVSNDKSQSAILENLSEGELYKK 2271
            LP+KK YEY+KVS ++ +GKS KV +SH +SPINF+IQ D+ E  LALGDIQEKLN+NYNGS FK+   +K  QAV+APFIVSGSD+ELFRA VLEKRKESPQ+HVLFIDYGNDEWVN+ETL N + +LV K GFA HC+L+LNIKKEAWS+A E+F+DL GYTEN+QG FVM+VI +DG+ LVVDLIS +KGSLTAILEKSGTCV K +EP+CNG     KLNG+SN+ + ++  EN +E  + K+
Sbjct:   31 LPEKKIYEYSKVSNEEYVGKSSKVTVSHFISPINFYIQFDEAESALALGDIQEKLNLNYNGSHFKNIDGLKINQAVVAPFIVSGSDSELFRAKVLEKRKESPQVHVLFIDYGNDEWVNFETLQNVDSDLVKKSGFAYHCQLNLNIKKEAWSNANEIFSDLIGYTENEQGGFVMEVIRLDGEKLVVDLISPMKGSLTAILEKSGTCVSKLSEPLCNGDNRISKLNGISNEHNSNSNYENYTEQGIIKE 277

[Close]

BLAST of tud-1 vs. TrEMBL
Match: A0A210R536 (Tudor domain-containing protein 1 OS=Mizuhopecten yessoensis OX=6573 GN=KP79_PYT16867 PE=4 SV=1)

HSP 1 Score: 66.6254 bits (161), Expect = 2.499e-7
Identity = 49/176 (27.84%), Postives = 84/176 (47.73%), Query Frame = 1

Query: 1585 IGKSFKVIMSHVVSPINFFIQLDDGEHQLALGDIQEKLNINYNGSPFKSAS----DVKETQAVIAPFIVSGSDAELFRAYVLEKRKESPQIHVLFIDYGNDEWVNYETLLNTNEELVSKPGFAIHCKLS-LNIKKEAWSHAIELFNDLAGYTENDQGTFVMQVISVDGDSLVVDLI 2097
            IG   +V +S V+ P N +IQ  + E+  AL  + +++   Y+ +    AS    DV   Q  +        D   +RA V + R+ S  + V ++DYGN E V    L    + + + P  A+ C L+ ++ KKE W  A+++   L   T      ++++  S  GD  VVD++
Sbjct:  575 IGSDIQVWVSEVIDPHNIWIQQPNEENIQALTLLMDEMKTIYDQTSEHVASPVVGDVYSAQFSL--------DGNWYRAKV-DGRQGSDMVTVTYLDYGNTETVAITKLRQLQDSMTTLPALAVKCSLADVSPKKEGWGEAVDVLLSLIPPTMASGVAYMIKARSGQGDCYVVDML 741

[Close]

BLAST of tud-1 vs. TrEMBL
Match: A0A3S1B5G2 (Uncharacterized protein OS=Elysia chlorotica OX=188477 GN=EGW08_011904 PE=4 SV=1)

HSP 1 Score: 64.6994 bits (156), Expect = 1.005e-6
Identity = 51/177 (28.81%), Postives = 90/177 (50.85%), Query Frame = 1

Query: 1585 IGKSFKVIMSHVVSPINFFIQLDDGEHQLALGDIQEKLNI-NYNGSPFKSASDVKETQAVIAPFIVSGSDAELFRAYVLEKRKESPQIHVLFIDYGNDEWVNYETLLNT-NEELVSKPGFAIHCKLSLNIKKEAWSHAIELFNDLAGYTENDQGTFVMQ---VISVDGDSLVVDLIS 2100
            +G +    +S+V SP  F++QL D E  + LG++ +++++ N+  S  +S  + +  QA +A F     D + +R  +  K  ++   +VLF+DYGN+E V+Y+  L     E  + P  A  C L       AW+   E F +     +  Q TF+ Q    I+++G  +  +LIS
Sbjct:  807 VGSTVTAFVSYVTSPSKFYVQLADKE--IELGELMDEISVYNHQSSGQESLLNPQVNQACMALF---SEDNQWYRGII--KSLQASSCNVLFVDYGNEESVSYKDALKILPSEFTTLPALAYECSLE-GTDGAAWTKEAEEFFESIIMDQELQCTFLSQKSVKITINGKDIKNELIS 975

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BLAST of tud-1 vs. Ensembl Cavefish
Match: si:ch211-189e2.3 (tudor domain-containing protein 6-like [Source:NCBI gene;Acc:103027511])

HSP 1 Score: 54.299 bits (129), Expect = 6.544e-7
Identity = 39/124 (31.45%), Postives = 57/124 (45.97%), Query Frame = 1

Query: 1600 KVIMSHVVSPINFFIQLDDGEHQLA-----LGDIQEKLNINYNGSPFKSASDVKETQAVIAPFIVSGSDAELFRAYVLEKRKESPQIHVLFIDYGNDEWVNYETLLNTNEELVSKPGFAIHCKL 1956
            +V +SH++SP +FF+QL   E+ L      L  I   +N     + F   S VK          V   D   +RA +  K      IHV FID+GN+  V   ++    E+ +  P F+IHC L
Sbjct:  983 EVYISHIISPNSFFVQLAKDENGLVSLTEELNSISSSVNNQAQMNYFPHGSLVK---------AVFPDDNSWYRAVI--KETNGKDIHVEFIDFGNEATVPATSVRKLEEQFLQVPRFSIHCSL 1095

[Close]

Query: 1600 KVIMSHVVSPINFFIQLDDGEHQLA-----LGDIQEKLNINYNGSPFKSASDVKETQAVIAPFIVSGSDAELFRAYVLEKRKESPQIHVLFIDYGNDEWVNYETLLNTNEELVSKPGFAIHCKL 1956
            +V +SH++SP +FF+QL   E+ L      L  I   +N     + F   S VK          V   D   +RA +  K      IHV FID+GN+  V   ++    E+ +  P F+IHC L
Sbjct:  983 EVYISHIISPNSFFVQLAKDENGLVSLTEELNSISSSVNNQAQMNYFPHGSLVK---------AVFPDDNSWYRAVI--KETNGKDIHVEFIDFGNEATVPATSVRKLEEQFLQVPRFSIHCSL 1095

[Close]

BLAST of tud-1 vs. Ensembl Cavefish
Match: si:ch211-189e2.3 (tudor domain-containing protein 6-like [Source:NCBI gene;Acc:103027511])

HSP 1 Score: 53.9138 bits (128), Expect = 6.972e-7
Identity = 39/124 (31.45%), Postives = 57/124 (45.97%), Query Frame = 1

Query: 1600 KVIMSHVVSPINFFIQLDDGEHQLA-----LGDIQEKLNINYNGSPFKSASDVKETQAVIAPFIVSGSDAELFRAYVLEKRKESPQIHVLFIDYGNDEWVNYETLLNTNEELVSKPGFAIHCKL 1956
            +V +SH++SP +FF+QL   E+ L      L  I   +N     + F   S VK          V   D   +RA +  K      IHV FID+GN+  V   ++    E+ +  P F+IHC L
Sbjct:  969 EVYISHIISPNSFFVQLAKDENGLVSLTEELNSISSSVNNQAQMNYFPHGSLVKA---------VFPDDNSWYRAVI--KETNGKDIHVEFIDFGNEATVPATSVRKLEEQFLQVPRFSIHCSL 1081

[Close]

BLAST of tud-1 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000009031.1 (pep scaffold:Pmarinus_7.0:GL480172:2151:16965:1 gene:ENSPMAG00000008166.1 transcript:ENSPMAT00000009031.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 50.8322 bits (120), Expect = 1.299e-6
Identity = 40/147 (27.21%), Postives = 70/147 (47.62%), Query Frame = 1

Query: 1588 GKSFKVIMSHVVSPINFFIQLDDGEHQLALGDIQEKLNINYNGSPFKSASDVKETQAVIAPFIVSGSDAELFRAYVLEKRKESPQIHVLFIDYGNDEWVNYETLLNTNEELVSKPGFAIHCKLS-----LNIKKEAWS-HAIELFND 2010
            G +  V + HVV+P  F++QL   E Q   G  +E  + + +G   +  SD+K    + A +    +D   +RA V     + P   V FIDYGN + V  +++   +   +  P  +I C L+     ++++   W+  A ELF +
Sbjct: 1210 GATLNVFVLHVVTPSRFYVQLVSDE-QTIYGLAEELNDGSVSGGSLRP-SDLKLGDLICAKY---SADESWYRAVVRGFEPDDPLALVEFIDYGNTDRVGSDSMSELHPVFLRHPRQSIACSLAGVRPCVSVRGNKWTKEAAELFTE 1351

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BLAST of tud-1 vs. Ensembl Nematostella
Match: EDO26981 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7TAI9])

HSP 1 Score: 51.6026 bits (122), Expect = 9.626e-8
Identity = 30/87 (34.48%), Postives = 43/87 (49.43%), Query Frame = 1

Query:  673 PKIGDFCLAKWTEDDCYYRAELLDILKDGSFKVTFVDEGTSGDIVTDLKHIPTGALQQYPKQFLKVSIGCSDAKELMSFILQESEGK 933
            P  GDFCLAK++ DD +YRA++L      S  V ++D G S  ++ D    P     Q P Q L   +   D  E  S  +Q+ E +
Sbjct:   19 PAQGDFCLAKFSFDDTWYRAKVLHCDSSFSITVQYIDYGNSETLMLDRVMEPPSQFLQLPPQALPCYLPGLDWGEAASEWIQQIENR 105

[Close]

BLAST of tud-1 vs. Ensembl Nematostella
Match: EDO36108 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SJJ0])

HSP 1 Score: 51.6026 bits (122), Expect = 1.548e-6
Identity = 40/151 (26.49%), Postives = 87/151 (57.62%), Query Frame = 1

Query:  556 RVDIILIRPVKSTENSKIEIADLLSQINSNK-SNLMPVDCPKIGDFCLAKWTEDDCYYRAELLDILKDGSFKVTFVDEGTSGDIVTDLKHIP-TGALQQYPKQFLKVSIG---CSDAKELMSFILQESEGKVIKIYWLGEYCDSVPVVNLF 993
            ++D I ++PV+S E+    +  L++ I  +K S ++P      G  CLAK+TED+ +YRA ++  ++D +F V +VD G +  +  D + +P + +  Q P Q ++ S+       ++++++ + +E + K +++  L +  +S+ +V L+
Sbjct: 1881 KIDEIWLQPVQSAEH----LESLMASIAESKPSGILPPTDRIEGKPCLAKFTEDNAWYRA-VITAVEDPTFHVRYVDFGNTECLPVD-RLVPISPSFLQLPTQAVRCSLHGFPADKSRQIVAQLNEELKDKTVEVEVLQQTSESI-LVKLY 2024

[Close]

BLAST of tud-1 vs. Ensembl Medaka
Match: amh (Oryzias latipes anti-Mullerian hormone (amh), mRNA. [Source:RefSeq mRNA;Acc:NM_001360941])

HSP 1 Score: 55.4546 bits (132), Expect = 2.809e-7
Identity = 41/126 (32.54%), Postives = 67/126 (53.17%), Query Frame = 1

Query: 1585 IGKSFKVIMSHVVSPINFFIQL-DDGEH-QLALGDIQEKLNINYNGSPFKSASDVKETQAVIAPFIVSGSDAELFRAYVLEKRKESPQIHVLFIDYGNDEWVNYETLLNTNEELVSKPGFAIHCKL 1956
            IG   +V +S++ SP +F+ QL  + +H QL +GD+Q     +Y  S F+  +   ET  V        S+   +RA V+ +R ++P + VLF+DYG+ E V+   L   + E ++  G A  C L
Sbjct:  697 IGSVLEVTVSYIESPNDFWCQLVQNMKHLQLLMGDLQ----YHYANSEFQHDA---ETSCVAQ----HPSNGMWYRALVV-RRHKTPHVDVLFVDYGHTETVSISALRKISPEFLTLDGQAFRCSL 810

[Close]

BLAST of tud-1 vs. Ensembl Medaka
Match: amh (Oryzias latipes anti-Mullerian hormone (amh), mRNA. [Source:RefSeq mRNA;Acc:NM_001360941])

HSP 1 Score: 55.4546 bits (132), Expect = 2.897e-7
Identity = 43/130 (33.08%), Postives = 70/130 (53.85%), Query Frame = 1

Query: 1585 IGKSFKVIMSHVVSPINFFIQL-DDGEH-QLALGDIQEKLNINYNGSPFKSASDVKETQAVIAPFIVSGSDAELFRAYVLEKRKESPQIHVLFIDYGNDEWVNYETLLNTNEELVSKPGFAIHCKLSLNI 1968
            IG   +V +S++ SP +F+ QL  + +H QL +GD+Q     +Y  S F+  +   ET  V        S+   +RA V+ +R ++P + VLF+DYG+ E V+   L   + E ++  G A  C L LN+
Sbjct:  697 IGSVLEVTVSYIESPNDFWCQLVQNMKHLQLLMGDLQ----YHYANSEFQHDA---ETSCVAQ----HPSNGMWYRALVV-RRHKTPHVDVLFVDYGHTETVSISALRKISPEFLTLDGQAFRCSL-LNL 813

[Close]

BLAST of tud-1 vs. Planmine SMEST
Match: SMESG000029236.1 (SMESG000029236.1)

HSP 1 Score: 1382.08 bits (3576), Expect = 0.000e+0
Identity = 716/716 (100.00%), Postives = 716/716 (100.00%), Query Frame = 1

Query:  172 MDEALEAVRIADKSDAFGDPIRASISKKCLDGMEXXXXXXXXXXXXXXYKGTDSFSRKSDSNFKDSEKYPTNNGDFAQVNRLNNVGRGRGIQTKIISGPPSFKTNEIKLNDIKLKTKELIDIEIVDLSRVDIILIRPVKSTENSKIEIADLLSQINSNKSNLMPVDCPKIGDFCLAKWTEDDCYYRAELLDILKDGSFKVTFVDEGTSGDIVTDLKHIPTGALQQYPKQFLKVSIGCSDAKELMSFILQESEGKVIKIYWLGEYCDSVPVVNLFLNEDEIVEKYTQINKVNIRKKFSQTFDDLPVHNLETNSHFSIAPSMYKNRNDFILQMKTFSVSLKQKKCPTVLPIPGDICIYEKRNANGESFLRCVILRRQLFSFDIELIDIGEKIMNVNIDHLYTVEDIHVKDAPCAITCDLDSSINIDGIKLPQDLIDGXXXXXXXXXXXXXXXXXXILPQKKAYEYAKVSYKDLIGKSFKVIMSHVVSPINFFIQLDDGEHQLALGDIQEKLNINYNGSPFKSASDVKETQAVIAPFIVSGSDAELFRAYVLEKRKESPQIHVLFIDYGNDEWVNYETLLNTNEELVSKPGFAIHCKLSLNIKKEAWSHAIELFNDLAGYTENDQGTFVMQVISVDGDSLVVDLISELKGSLTAILEKSGTCVKSNEPICNGGGPQVKLNGVSNDKSQSAILENLSEGELYKKFIELERRLSALEILMK 2319
            MDEALEAVRIADKSDAFGDPIRASISKKCLDGMENNQNRSNNNRNDSSYKGTDSFSRKSDSNFKDSEKYPTNNGDFAQVNRLNNVGRGRGIQTKIISGPPSFKTNEIKLNDIKLKTKELIDIEIVDLSRVDIILIRPVKSTENSKIEIADLLSQINSNKSNLMPVDCPKIGDFCLAKWTEDDCYYRAELLDILKDGSFKVTFVDEGTSGDIVTDLKHIPTGALQQYPKQFLKVSIGCSDAKELMSFILQESEGKVIKIYWLGEYCDSVPVVNLFLNEDEIVEKYTQINKVNIRKKFSQTFDDLPVHNLETNSHFSIAPSMYKNRNDFILQMKTFSVSLKQKKCPTVLPIPGDICIYEKRNANGESFLRCVILRRQLFSFDIELIDIGEKIMNVNIDHLYTVEDIHVKDAPCAITCDLDSSINIDGIKLPQDLIDGVLFNLKKYNKNNKYTVNFILPQKKAYEYAKVSYKDLIGKSFKVIMSHVVSPINFFIQLDDGEHQLALGDIQEKLNINYNGSPFKSASDVKETQAVIAPFIVSGSDAELFRAYVLEKRKESPQIHVLFIDYGNDEWVNYETLLNTNEELVSKPGFAIHCKLSLNIKKEAWSHAIELFNDLAGYTENDQGTFVMQVISVDGDSLVVDLISELKGSLTAILEKSGTCVKSNEPICNGGGPQVKLNGVSNDKSQSAILENLSEGELYKKFIELERRLSALEILMK
Sbjct:    1 MDEALEAVRIADKSDAFGDPIRASISKKCLDGMENNQNRSNNNRNDSSYKGTDSFSRKSDSNFKDSEKYPTNNGDFAQVNRLNNVGRGRGIQTKIISGPPSFKTNEIKLNDIKLKTKELIDIEIVDLSRVDIILIRPVKSTENSKIEIADLLSQINSNKSNLMPVDCPKIGDFCLAKWTEDDCYYRAELLDILKDGSFKVTFVDEGTSGDIVTDLKHIPTGALQQYPKQFLKVSIGCSDAKELMSFILQESEGKVIKIYWLGEYCDSVPVVNLFLNEDEIVEKYTQINKVNIRKKFSQTFDDLPVHNLETNSHFSIAPSMYKNRNDFILQMKTFSVSLKQKKCPTVLPIPGDICIYEKRNANGESFLRCVILRRQLFSFDIELIDIGEKIMNVNIDHLYTVEDIHVKDAPCAITCDLDSSINIDGIKLPQDLIDGVLFNLKKYNKNNKYTVNFILPQKKAYEYAKVSYKDLIGKSFKVIMSHVVSPINFFIQLDDGEHQLALGDIQEKLNINYNGSPFKSASDVKETQAVIAPFIVSGSDAELFRAYVLEKRKESPQIHVLFIDYGNDEWVNYETLLNTNEELVSKPGFAIHCKLSLNIKKEAWSHAIELFNDLAGYTENDQGTFVMQVISVDGDSLVVDLISELKGSLTAILEKSGTCVKSNEPICNGGGPQVKLNGVSNDKSQSAILENLSEGELYKKFIELERRLSALEILMK 716

[Close]

BLAST of tud-1 vs. Planmine SMEST
Match: SMESG000029232.1 (SMESG000029232.1)

HSP 1 Score: 1382.08 bits (3576), Expect = 0.000e+0
Identity = 716/716 (100.00%), Postives = 716/716 (100.00%), Query Frame = 1

Query:  172 MDEALEAVRIADKSDAFGDPIRASISKKCLDGMEXXXXXXXXXXXXXXYKGTDSFSRKSDSNFKDSEKYPTNNGDFAQVNRLNNVGRGRGIQTKIISGPPSFKTNEIKLNDIKLKTKELIDIEIVDLSRVDIILIRPVKSTENSKIEIADLLSQINSNKSNLMPVDCPKIGDFCLAKWTEDDCYYRAELLDILKDGSFKVTFVDEGTSGDIVTDLKHIPTGALQQYPKQFLKVSIGCSDAKELMSFILQESEGKVIKIYWLGEYCDSVPVVNLFLNEDEIVEKYTQINKVNIRKKFSQTFDDLPVHNLETNSHFSIAPSMYKNRNDFILQMKTFSVSLKQKKCPTVLPIPGDICIYEKRNANGESFLRCVILRRQLFSFDIELIDIGEKIMNVNIDHLYTVEDIHVKDAPCAITCDLDSSINIDGIKLPQDLIDGXXXXXXXXXXXXXXXXXXILPQKKAYEYAKVSYKDLIGKSFKVIMSHVVSPINFFIQLDDGEHQLALGDIQEKLNINYNGSPFKSASDVKETQAVIAPFIVSGSDAELFRAYVLEKRKESPQIHVLFIDYGNDEWVNYETLLNTNEELVSKPGFAIHCKLSLNIKKEAWSHAIELFNDLAGYTENDQGTFVMQVISVDGDSLVVDLISELKGSLTAILEKSGTCVKSNEPICNGGGPQVKLNGVSNDKSQSAILENLSEGELYKKFIELERRLSALEILMK 2319
            MDEALEAVRIADKSDAFGDPIRASISKKCLDGMENNQNRSNNNRNDSSYKGTDSFSRKSDSNFKDSEKYPTNNGDFAQVNRLNNVGRGRGIQTKIISGPPSFKTNEIKLNDIKLKTKELIDIEIVDLSRVDIILIRPVKSTENSKIEIADLLSQINSNKSNLMPVDCPKIGDFCLAKWTEDDCYYRAELLDILKDGSFKVTFVDEGTSGDIVTDLKHIPTGALQQYPKQFLKVSIGCSDAKELMSFILQESEGKVIKIYWLGEYCDSVPVVNLFLNEDEIVEKYTQINKVNIRKKFSQTFDDLPVHNLETNSHFSIAPSMYKNRNDFILQMKTFSVSLKQKKCPTVLPIPGDICIYEKRNANGESFLRCVILRRQLFSFDIELIDIGEKIMNVNIDHLYTVEDIHVKDAPCAITCDLDSSINIDGIKLPQDLIDGVLFNLKKYNKNNKYTVNFILPQKKAYEYAKVSYKDLIGKSFKVIMSHVVSPINFFIQLDDGEHQLALGDIQEKLNINYNGSPFKSASDVKETQAVIAPFIVSGSDAELFRAYVLEKRKESPQIHVLFIDYGNDEWVNYETLLNTNEELVSKPGFAIHCKLSLNIKKEAWSHAIELFNDLAGYTENDQGTFVMQVISVDGDSLVVDLISELKGSLTAILEKSGTCVKSNEPICNGGGPQVKLNGVSNDKSQSAILENLSEGELYKKFIELERRLSALEILMK
Sbjct:    1 MDEALEAVRIADKSDAFGDPIRASISKKCLDGMENNQNRSNNNRNDSSYKGTDSFSRKSDSNFKDSEKYPTNNGDFAQVNRLNNVGRGRGIQTKIISGPPSFKTNEIKLNDIKLKTKELIDIEIVDLSRVDIILIRPVKSTENSKIEIADLLSQINSNKSNLMPVDCPKIGDFCLAKWTEDDCYYRAELLDILKDGSFKVTFVDEGTSGDIVTDLKHIPTGALQQYPKQFLKVSIGCSDAKELMSFILQESEGKVIKIYWLGEYCDSVPVVNLFLNEDEIVEKYTQINKVNIRKKFSQTFDDLPVHNLETNSHFSIAPSMYKNRNDFILQMKTFSVSLKQKKCPTVLPIPGDICIYEKRNANGESFLRCVILRRQLFSFDIELIDIGEKIMNVNIDHLYTVEDIHVKDAPCAITCDLDSSINIDGIKLPQDLIDGVLFNLKKYNKNNKYTVNFILPQKKAYEYAKVSYKDLIGKSFKVIMSHVVSPINFFIQLDDGEHQLALGDIQEKLNINYNGSPFKSASDVKETQAVIAPFIVSGSDAELFRAYVLEKRKESPQIHVLFIDYGNDEWVNYETLLNTNEELVSKPGFAIHCKLSLNIKKEAWSHAIELFNDLAGYTENDQGTFVMQVISVDGDSLVVDLISELKGSLTAILEKSGTCVKSNEPICNGGGPQVKLNGVSNDKSQSAILENLSEGELYKKFIELERRLSALEILMK 716

[Close]

BLAST of tud-1 vs. Planmine SMEST
Match: SMESG000043684.1 (SMESG000043684.1)

HSP 1 Score: 256.529 bits (654), Expect = 2.070e-74
Identity = 210/708 (29.66%), Postives = 342/708 (48.31%), Query Frame = 1

Query:   28 VFLTNLPKSINEVVVKNLFSSAGKVLKVKIIDDKRNENQKLCFVGFRTMDEALEAVRIADKSDAFGDPIRASISKKCLDGMEXXXXXXXXXXXXXXYKGTDSFSRKSDSNFKDSEKYPTNNGDFAQVNRLNNVGRGRGIQTKIISGPPSFKTNEIKLNDIKLKTKELIDIEIVDLSRVDIILIRPVKSTENSKIEIADLLSQINSNKSNLMPVDCPKIGDFCLAKWTEDDCYYRAELLDILKDGSFKVTFVDEGTSGDIVTDLKHIPTGALQQYPKQFLKVSIGCSDAKELMSFILQESEGKVIKIYWL-GEYCDSVPVVNLFLNEDEIVEKYTQINKVNIRKKFSQTFDDLPVHNLETNSHFS---IAPSMYKNRNDF-ILQMKTFSVSLKQKKCPTVLPIPGDICIYEKRNANGESFL-RCVILRRQL----FSFDIELIDIGEKIMNVNIDHLYTVEDIHVKDAPCAITCDLDSSINIDGIKLPQDLIDGXXXXXXXXXXXXXXXXXXILPQKKAYEYAKVSYK------DLIGKSFKVIMSHVVSPINFFIQLDDGEHQLALGDIQEKLNINYNGSPFKSASDVKETQAVIAPFIVSGSDAELFRAYVLEKRKESPQIHVLFIDYGNDEWVNYETLLNTNEELVSKPGFAIHCKLSLNIKKEAWSHAIELFNDLAGYTENDQGTFVMQVISVDGDSLVVDLISE 2103
            + +TN+  ++++ +++N F   G++L   I  DK N + K+C++ + +++EA +A+ + DKS   G+P+R S  K                      + TD      +SN                V R+ + GRGRG+  +     P    + I L+ I +     I +EI++L+ V  IL RP+  TE+SK ++ D+L  +N N  +L  V  P+I  F +AKWT+D+ +YRA+LL+   +  +KV FVDEGTSGDIV +LK IP   +   P QFL   + C  ++EL + I+       + IY   GE  D    +NLFLN+ ++++ Y   ++ N   + ++  ++  +   + NS FS   +     ++R+ F I+ +  F ++ K +      PI GD+ IY +     ES+L RCV+   +       + I L+D    I   + D L+      ++  P  I C +D  +N D + LP + ++             K  +  I  +K  Y  + V  K       LIG+   VI+SHV S   F+++  D      L  IQ+ +N NY  S F S  ++ + + VIAPF+      E FRA + E   E   I+V FIDYGN EWV    L+     + + P  A  C+L + I+ E  S  ++L   L  Y EN Q    ++V+S       VDL +E
Sbjct:    5 ILITNINTTVDDRLLRNTFEKIGRILYFNICMDKFNPSTKICYINYSSVEEAHKAIELYDKSIDLGEPLRISFKK--------------------ITQVTDKGLMNGNSN--------------KSVTRMQSFGRGRGMINEC-GRVPRLTQSCIVLSYINIPLNTKIRVEIIELNDVSSILARPLILTEDSKPQLTDILDVVNDNVHSLADVRVPEINCFYMAKWTDDNKFYRAKLLEKSGNNQYKVCFVDEGTSGDIVRELKEIPR-EVADIPSQFLPCDMQCEPSEELNNLIISNGNNSQVNIYVTNGELIDGKYRINLFLNDIDVIKLYK--DEYNRDPRINKIPNECDLKKYKINSEFSDFQLINYPKEHRDIFEIVLIDPFRINPKMEPLSGS-PIKGDVLIYRQ----SESYLHRCVVESTRFVNTTLHYTIRLVDENRSIETAS-DSLFQTNFQCLETPPRIIRCVMD--LNCDRL-LPGEEVE-------------KIKIVDIDQKKNLYAISVVKAKPIKPIQKLIGQRISVILSHVESSEEFYVRFSDDNTSENLNCIQDIINSNYPLSSFSSTRELSKNEIVIAPFM-----EENFRATIKEINSEKSLIYVFFIDYGNYEWVKLVDLVRLKGNISALPAVAKKCRLPVEIQSEKNSEVVQL---LMEYCENGQVPVTVEVVSDSNGIFTVDLFAE 644

[Close]

BLAST of tud-1 vs. Planmine SMEST
Match: SMESG000081435.1 (SMESG000081435.1)

HSP 1 Score: 59.3066 bits (142), Expect = 1.310e-10
Identity = 29/57 (50.88%), Postives = 39/57 (68.42%), Query Frame = 1

Query:  694 LAKWTEDDCYYRAELLDILKDGSFKVTFVDEGTSGDIVTDLKHIPTGALQQYPKQFL 864
            +AKW +D+ +YRA+ L+   +  +KV FVDE TSG+IV +LK IP G L   P QFL
Sbjct:    1 MAKWIDDNKFYRAKHLEKSVNNQYKVCFVDERTSGEIVRELKEIPKGVL-DVPSQFL 56

[Close]

BLAST of tud-1 vs. Planmine SMEST
Match: SMESG000062403.1 (SMESG000062403.1)

HSP 1 Score: 50.0618 bits (118), Expect = 7.340e-6
Identity = 32/97 (32.99%), Postives = 49/97 (50.52%), Query Frame = 1

Query:  595 ENSKIEIADLLSQINSNKSNLMPVDCPKIGDFCLAKWTEDDCYYRAELLDILKDGSFKVTFVDEGTSG-DIVTDLKHIPTGALQQYPKQFLKVSIGC 882
            EN  I I   L       S++     PK GD C AK+T D C+YRA+++ I    +  + +VD G    +  + L  +P+G LQ+ P Q  + S+ C
Sbjct:  721 ENVIINITKELQSYFMEHSHVPGAYKPKKGDLCAAKFTLDGCWYRAKVIKIDNPKAINLLYVDFGNEEINEESSLASLPSG-LQKIPYQATEYSLAC 816

The following BLAST results are available for this feature:

BLAST of tud-1 vs. Ensembl Human
BLAST of tud-1 vs. Ensembl Celegans
BLAST of tud-1 vs. Ensembl Fly
BLAST of tud-1 vs. Ensembl Zebrafish
BLAST of tud-1 vs. Ensembl Xenopus
BLAST of tud-1 vs. Ensembl Mouse
BLAST of tud-1 vs. UniProt/SwissProt
BLAST of tud-1 vs. TrEMBL
BLAST of tud-1 vs. Ensembl Cavefish
BLAST of tud-1 vs. Ensembl Sea Lamprey
BLAST of tud-1 vs. Ensembl Yeast
BLAST of tud-1 vs. Ensembl Nematostella
BLAST of tud-1 vs. Ensembl Medaka
BLAST of tud-1 vs. Planmine SMEST

BLAST of tud-1 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 0


Match Name	E-value	Identity	Description

BLAST of tud-1 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 0


Match Name	E-value	Identity	Description

BLAST of tud-1 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 0


Match Name	E-value	Identity	Description

BLAST of tud-1 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5


Match Name	E-value	Identity	Description
tdrd6	1.469e-6	29.69	tudor domain containing 6 [Source:ZFIN;Acc:ZDB-GEN...	[more]
tdrd6	1.469e-6	29.69	tudor domain containing 6 [Source:ZFIN;Acc:ZDB-GEN...	[more]
si:ch211-189e2.3	5.355e-6	26.24	si:ch211-189e2.3 [Source:ZFIN;Acc:ZDB-GENE-030131-...	[more]
si:ch211-189e2.3	5.793e-6	26.24	si:ch211-189e2.3 [Source:ZFIN;Acc:ZDB-GENE-030131-...	[more]
si:ch211-189e2.3	6.045e-6	26.24	si:ch211-189e2.3 [Source:ZFIN;Acc:ZDB-GENE-030131-...	[more]

BLAST of tud-1 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 1


Match Name	E-value	Identity	Description
ENSXETT00000011761.1	2.937e-7	31.75	ring finger protein 17 [Source:NCBI gene;Acc:10049...	[more]

BLAST of tud-1 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 0


Match Name	E-value	Identity	Description

BLAST of tud-1 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 0


Match Name	E-value	Identity	Description

BLAST of tud-1 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5


Match Name	E-value	Identity	Description
V5W3W8	0.000e+0	99.87	Tud-1 OS=Schmidtea mediterranea OX=79327 PE=2 SV=1	[more]
C0L3L0	0.000e+0	88.31	Tudor domain containing 1 OS=Schmidtea polychroa O...	[more]
A4V6J8	1.195e-105	66.80	Tudor protein (Fragment) OS=Dugesia japonica OX=61...	[more]
A0A210R536	2.499e-7	27.84	Tudor domain-containing protein 1 OS=Mizuhopecten ...	[more]
A0A3S1B5G2	1.005e-6	28.81	Uncharacterized protein OS=Elysia chlorotica OX=18...	[more]

BLAST of tud-1 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 3


Match Name	E-value	Identity	Description
si:ch211-189e2.3	6.544e-7	31.45	tudor domain-containing protein 6-like [Source:NCB...	[more]
si:ch211-189e2.3	6.544e-7	31.45	tudor domain-containing protein 6-like [Source:NCB...	[more]
si:ch211-189e2.3	6.972e-7	31.45	tudor domain-containing protein 6-like [Source:NCB...	[more]

BLAST of tud-1 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 1


Match Name	E-value	Identity	Description
ENSPMAT00000009031.1	1.299e-6	27.21	pep scaffold:Pmarinus_7.0:GL480172:2151:16965:1 ge...	[more]

BLAST of tud-1 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0


Match Name	E-value	Identity	Description

BLAST of tud-1 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 2


Match Name	E-value	Identity	Description
EDO26981	9.626e-8	34.48	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO36108	1.548e-6	26.49	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]

BLAST of tud-1 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 2


Match Name	E-value	Identity	Description
amh	2.809e-7	32.54	Oryzias latipes anti-Mullerian hormone (amh), mRNA...	[more]
amh	2.897e-7	33.08	Oryzias latipes anti-Mullerian hormone (amh), mRNA...	[more]

BLAST of tud-1 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5


Match Name	E-value	Identity	Description
SMESG000029236.1	0.000e+0	100.00	SMESG000029236.1	[more]
SMESG000029232.1	0.000e+0	100.00	SMESG000029232.1	[more]
SMESG000043684.1	2.070e-74	29.66	SMESG000043684.1	[more]
SMESG000081435.1	1.310e-10	50.88	SMESG000081435.1	[more]
SMESG000062403.1	7.340e-6	32.99	SMESG000062403.1	[more]

Analyses

This transcript is derived from or has results from the following analyses


Analysis Name	Date Performed
Embryonic Stages	2016-07-25
Schmidtea mediterranea smed_20140614 BLASTX Human e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL	2020-05-01
Schmidtea mediterranea Sexual smed_20140614 transcriptome	2016-07-25
Schmidtea mediteranean smed_20140614 Interproscan	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST	2020-05-08

Cross References

External references for this transcript


Database	Accession
SmedGD GBrowse	SMED30013909
GenBank	AHC00376.1

Sequences

The following sequences are available for this feature:

transcript sequence
protein sequence

transcript sequence

>SMED30013909 ID=SMED30013909|Name=tud-1|organism=Schmidtea mediterranea sexual|type=transcript|length=2414bp
ATTTAGAAAATGGAGGCAACTTGCGATGTTTTTTTAACGAATTTACCTAA
GTCGATTAATGAAGTAGTTGTGAAGAACTTATTTTCTTCTGCTGGGAAAG
TGTTAAAAGTGAAAATAATAGATGACAAAAGAAACGAAAATCAGAAGCTA
TGCTTCGTTGGATTTCGAACTATGGATGAAGCATTAGAAGCCGTCAGAAT
TGCAGATAAATCTGATGCGTTTGGTGATCCAATTAGAGCCAGTATATCAA
AGAAGTGTTTAGACGGAATGGAGAATAATCAAAATAGATCAAATAATAAC
AGAAATGATTCAAGTTATAAAGGAACTGATTCATTTTCAAGAAAGAGTGA
TTCTAATTTCAAGGATAGTGAAAAGTATCCAACAAACAATGGTGACTTTG
CACAAGTAAATCGTTTAAACAACGTTGGAAGAGGAAGAGGAATCCAGACT
AAAATTATTAGTGGTCCACCTTCATTCAAAACTAATGAAATTAAGTTAAA
CGATATTAAACTTAAAACAAAAGAACTGATTGACATCGAAATCGTCGATT
TAAGTAGAGTTGACATTATACTTATAAGGCCAGTAAAGTCAACGGAAAAT
TCAAAAATTGAAATAGCAGATTTATTGTCACAAATAAATTCAAATAAATC
GAATCTAATGCCAGTTGACTGTCCTAAAATAGGAGATTTTTGTCTTGCAA
AATGGACTGAAGATGATTGCTATTATCGGGCTGAATTGTTAGATATATTA
AAGGATGGATCTTTCAAAGTTACTTTTGTTGATGAAGGAACTTCGGGTGA
TATTGTGACTGATTTGAAACACATTCCGACTGGTGCTTTACAGCAGTATC
CTAAACAATTTTTGAAGGTTTCAATCGGTTGCTCAGACGCAAAAGAATTA
ATGTCATTTATTTTACAAGAGTCTGAAGGAAAGGTGATTAAAATTTATTG
GCTCGGAGAATATTGTGATTCCGTGCCTGTTGTAAATTTATTTCTGAATG
AAGATGAAATTGTGGAAAAATATACCCAAATAAATAAAGTAAATATCAGG
AAAAAATTCTCACAGACATTTGATGATCTCCCAGTACATAACCTCGAAAC
TAATTCACATTTTTCAATAGCACCATCAATGTATAAAAACCGAAATGATT
TTATTCTTCAGATGAAAACTTTCTCGGTATCTTTAAAGCAAAAAAAATGT
CCTACGGTTTTACCAATTCCTGGTGATATATGTATATATGAGAAAAGGAA
TGCTAATGGCGAATCATTTCTTCGTTGTGTTATATTAAGGCGCCAACTTT
TTTCTTTTGACATCGAGTTAATAGATATCGGTGAAAAAATAATGAATGTT
AATATTGATCACCTGTACACAGTCGAAGATATTCATGTAAAAGACGCTCC
CTGTGCTATTACTTGCGATTTAGATAGTTCTATTAATATAGATGGTATTA
AGCTCCCTCAAGATTTGATCGATGGTGTTCTCTTTAATCTTAAAAAGTAC
AACAAAAATAATAAATACACTGTAAATTTCATTTTACCACAAAAGAAAGC
TTATGAATATGCAAAAGTATCATATAAAGATTTGATTGGTAAAAGCTTTA
AAGTAATAATGTCGCACGTTGTCTCTCCCATTAATTTCTTTATTCAACTT
GATGATGGAGAGCATCAGCTTGCACTTGGAGATATTCAAGAAAAATTAAA
TATTAATTATAATGGATCACCATTCAAAAGTGCTAGCGATGTTAAAGAAA
CTCAGGCAGTTATTGCTCCTTTTATTGTTTCCGGAAGTGATGCGGAACTT
TTTCGGGCTTATGTTTTAGAGAAACGAAAGGAATCTCCACAAATTCATGT
ATTGTTTATTGATTATGGTAATGATGAATGGGTGAATTATGAAACTTTAC
TGAATACAAATGAAGAATTAGTTTCTAAACCAGGTTTCGCAATACATTGT
AAATTATCTCTAAATATTAAGAAGGAAGCGTGGAGTCACGCTATTGAATT
ATTTAATGATTTAGCTGGTTATACTGAAAATGACCAGGGGACGTTTGTAA
TGCAGGTTATTAGTGTCGATGGTGATTCGTTAGTTGTGGACTTGATTTCA
GAACTGAAAGGTTCGTTGACGGCCATCTTAGAAAAAAGTGGTACATGTGT
AAAGTCCAATGAACCAATATGTAATGGAGGAGGACCCCAAGTTAAATTAA
ATGGCGTTTCAAATGATAAATCTCAATCAGCTATTCTTGAAAATTTATCT
GAAGGAGAATTATATAAAAAATTTATTGAACTAGAACGGAGATTAAGTGC
TTTAGAGATATTGATGAAATAATGCTACCCGCGCAATTAGTATTATCAAA
TTATGATAATCTAGTCTTGATGTGTTTAAAATTTTGTATTTTAACATAAA
TTTATTCCGTGTTG

protein sequence of SMED30013909-orf-1

>SMED30013909-orf-1 ID=SMED30013909-orf-1|Name=SMED30013909-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=771bp
MEATCDVFLTNLPKSINEVVVKNLFSSAGKVLKVKIIDDKRNENQKLCFV
GFRTMDEALEAVRIADKSDAFGDPIRASISKKCLDGMENNQNRSNNNRND
SSYKGTDSFSRKSDSNFKDSEKYPTNNGDFAQVNRLNNVGRGRGIQTKII
SGPPSFKTNEIKLNDIKLKTKELIDIEIVDLSRVDIILIRPVKSTENSKI
EIADLLSQINSNKSNLMPVDCPKIGDFCLAKWTEDDCYYRAELLDILKDG
SFKVTFVDEGTSGDIVTDLKHIPTGALQQYPKQFLKVSIGCSDAKELMSF
ILQESEGKVIKIYWLGEYCDSVPVVNLFLNEDEIVEKYTQINKVNIRKKF
SQTFDDLPVHNLETNSHFSIAPSMYKNRNDFILQMKTFSVSLKQKKCPTV
LPIPGDICIYEKRNANGESFLRCVILRRQLFSFDIELIDIGEKIMNVNID
HLYTVEDIHVKDAPCAITCDLDSSINIDGIKLPQDLIDGVLFNLKKYNKN
NKYTVNFILPQKKAYEYAKVSYKDLIGKSFKVIMSHVVSPINFFIQLDDG
EHQLALGDIQEKLNINYNGSPFKSASDVKETQAVIAPFIVSGSDAELFRA
YVLEKRKESPQIHVLFIDYGNDEWVNYETLLNTNEELVSKPGFAIHCKLS
LNIKKEAWSHAIELFNDLAGYTENDQGTFVMQVISVDGDSLVVDLISELK
GSLTAILEKSGTCVKSNEPICNGGGPQVKLNGVSNDKSQSAILENLSEGE
LYKKFIELERRLSALEILMK*

Aliases

The feature 'tud-1' has the following synonyms


Synonym
tud-1

Annotated Terms

The following terms have been associated with this transcript:

Vocabulary: **molecular function**
Term	Definition
GO:0003723	RNA binding
GO:0003676	nucleic acid binding
GO:0000166	nucleotide binding

Vocabulary: **Planarian Anatomy**
Term	Definition
PLANA:0000099	neuron
PLANA:0002109	X1 cell
PLANA:0002111	X2 cell
PLANA:0002142	parenchyma
PLANA:0004517	blastomere
PLANA:0000429	neoblast

Vocabulary: **Schmidtea mediterranea Developmental Stages**
Term	Definition
PLANA:0000003	Stage 3
PLANA:0000005	Stage 5
PLANA:0000008	Stage 8
PLANA:0000004	Stage 4
PLANA:0000007	Stage 7
PLANA:0000002	Stage 2
PLANA:0000006	Stage 6

Vocabulary: **INTERPRO**
Term	Definition
IPR035979	RBD_domain_sf
IPR002999	Tudor
IPR000504	RRM_dom
IPR012677	Nucleotide-bd_a/b_plait_sf

InterPro

Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01


IPR Term	IPR Description	Source	Source Term	Source Description	Alignment
IPR002999	Tudor domain	SMART	SM00333	TUDOR_7	coord: 576..638 e-value: 0.0035 score: 26.6 coord: 220..280 e-value: 3.4E-6 score: 36.6
IPR002999	Tudor domain	PFAM	PF00567	TUDOR	coord: 527..650 e-value: 2.9E-14 score: 53.1 coord: 195..288 e-value: 8.8E-10 score: 38.7
IPR002999	Tudor domain	PROSITE	PS50304	TUDOR	coord: 580..640 score: 10.744
IPR002999	Tudor domain	PROSITE	PS50304	TUDOR	coord: 221..279 score: 11.51
IPR000504	RNA recognition motif domain	SMART	SM00360	rrm1_1	coord: 6..78 e-value: 2.0E-9 score: 47.3
IPR000504	RNA recognition motif domain	PFAM	PF00076	RRM_1	coord: 7..67 e-value: 5.1E-10 score: 39.0
IPR000504	RNA recognition motif domain	PROSITE	PS50102	RRM	coord: 5..82 score: 12.987
None	No IPR available	GENE3D	G3DSA:2.40.50.790		coord: 198..335 e-value: 4.6E-17 score: 64.4
None	No IPR available	GENE3D	G3DSA:2.30.30.140		coord: 199..280 e-value: 4.6E-17 score: 64.4 coord: 551..640 e-value: 1.3E-18 score: 69.4
None	No IPR available	GENE3D	G3DSA:2.40.50.790		coord: 537..697 e-value: 1.3E-18 score: 69.4
None	No IPR available	MOBIDB_LITE	mobidb-lite	disorder_prediction	coord: 86..130
None	No IPR available	MOBIDB_LITE	mobidb-lite	disorder_prediction	coord: 105..119
None	No IPR available	MOBIDB_LITE	mobidb-lite	disorder_prediction	coord: 86..104
None	No IPR available	PANTHER	PTHR22948	TUDOR DOMAIN CONTAINING PROTEIN	coord: 206..277 coord: 526..668
None	No IPR available	CDD	cd00590	RRM_SF	coord: 7..78 e-value: 2.43926E-12 score: 60.7817
None	No IPR available	CDD	cd04508	TUDOR	coord: 225..271 e-value: 7.4415E-12 score: 58.3783
None	No IPR available	CDD	cd04508	TUDOR	coord: 582..630 e-value: 0.00137329 score: 35.2664
None	No IPR available	SUPERFAMILY	SSF63748	Tudor/PWWP/MBT	coord: 557..650
None	No IPR available	SUPERFAMILY	SSF63748	Tudor/PWWP/MBT	coord: 208..288
IPR012677	Nucleotide-binding alpha-beta plait domain superfamily	GENE3D	G3DSA:3.30.70.330		coord: 1..82 e-value: 9.1E-13 score: 50.2
IPR035979	RNA-binding domain superfamily	SUPERFAMILY	SSF54928	RNA-binding domain, RBD	coord: 5..108

Main menu

tud-1

Zeng et. al., 2018

▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Overview

Single cell RNA-seq of pluripotent neoblasts and its early progenies

Explore this single cell expression dataset with our NB Cluster Shiny App

Neoblast Population

Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Davies et. al., 2017

piwi-1+ blastomeres co-express the adult asexual neoblast enriched gene tud-1.
SPIM reconstructed S4 embryo costained with piwi-1 (red) and tud-1 (green). piwi-1+ blastomeres co-express the nuage factor tud-1, and virtually all tud-1+ cells co-express piwi-1.

piwi-1+ blastomeres co-express the adult asexual neoblast enriched gene tud-1.
SPIM reconstructed S5 embryo costained with piwi-1 (red) and tud-1 (green). piwi-1+ blastomeres co-express the nuage factor tud-1, and virtually all tud-1+ cells co-express piwi-1.

piwi-1+ blastomeres co-express the adult asexual neoblast enriched gene tud-1.
SPIM reconstructed S3 embryo costained with piwi-1 (red) and tud-1 (green). piwi-1+ blastomeres co-express the nuage factor tud-1, and virtually all tud-1+ cells co-express piwi-1.

PAGE et. al., 2020

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE

PAGE Curations: 47

Owlery

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