OFD1

Overview


Name	OFD1 (AFB74720.1)
Smed ID	SMED30013865
Length (bp)	2784

Neoblast Clusters

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Overview

Single cell RNA-seq of pluripotent neoblasts and its early progenies

We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)

Explore this single cell expression dataset with our NB Cluster Shiny App

Neoblast Population

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.

Expression of OFD1 (SMED30013865) t-SNE clustered cells

Violin plots show distribution of expression levels for OFD1 (SMED30013865) in cells (dots) of each of the 12 neoblast clusters.

Sub-lethal Irradiated Surviving X1 and X2 Cell Population

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of OFD1 (SMED30013865) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for OFD1 (SMED30013865) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

Anatomical Expression

PAGE et. al., 2020

SMED30013865

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE

PAGE Curations: 8

Expressed In	Reference Transcript	Gene Models	Published Transcript	Transcriptome	Publication
head region	SMED30013865	h1SMcG0005964	SmedASXL_015827	SmedAsxl_ww_GCZZ01	PMID:27034770 Currie et al., 2016
pharynx	SMED30013865	h1SMcG0005964	dd_Smed_v4_13339_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
nervous system	SMED30013865	h1SMcG0005964	dd_Smed_v4_13339_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
epidermis	SMED30013865	h1SMcG0005964	dd_Smed_v4_13339_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
cephalic ganglia	SMED30013865	h1SMcG0005964	dd_Smed_v4_13339_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
parenchyma	SMED30013865	h1SMcG0005964	dd_Smed_v4_13339_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
head region	SMED30013865	h1SMcG0005964	dd_Smed_v6_13339_0_1	dd_Smed_v6	PMID:28171748 Stückemann et al., 2017
epidermis	SMED30013865	h1SMcG0005964	dd_Smed_v4_13339_0_1	dd_Smed_v4	PMID:28292427 Wurtzel et al., 2017

Note: Hover over icons to view figure legend

Homology

[Close]

BLAST of OFD1 vs. Ensembl Human
Match: OFD1 (OFD1 centriole and centriolar satellite protein [Source:HGNC Symbol;Acc:HGNC:2567])

HSP 1 Score: 136.732 bits (343), Expect = 3.772e-32
Identity = 145/545 (26.61%), Postives = 270/545 (49.54%), Query Frame = 3

Query:   72 YSTKSVKTDLNFQNKLLKLMKEKGVVDKLKTQVRQNLISEIAAKESIFNLKNNSNDKPEKSFDIFYHSSSSAIYEYLDKNNFHFTKSVFVPESGIKNDKFYTAEELLRVLQLDKNSEFYKKLQSDLLNTDK----SFILCLLKTISEYHTFKQS-EIEIQTDKPEKFIPLSEKLQKLDLQFEDRQKQGTLKTQQLYEDRIVAFQRDMEKRLRQEMENEIQRFKDHEILSIKRNAEEEFNKALKSKLKIMEEEYQNRLAALKDRERASQENHQQFKDSQERENYFQRQQILRDLSNIQERELQMKKEKEHLEREFEMMKEQHKIKLNQVEERNSKLKELEMGINMKITQEVNSYKLNEEKRLVQKWKEVEVFEMKLQEEKKYLDSEKCTVEKLKEELTKRQYLFNEMDL------ISYPVLKQQNNSLLDQIEEFKXXXXXXXXXXXXDKHRISCLLKQKM---------------GPNFEQSVLSNELERARDIFKRERSVLEEQKEALEKRLLEEIKSKRILTDQLSQQQDLVEMLSRQISENK 1628
            ++   V +    + KL +  K++G++D LKTQ+R  LI E+        L+  S      S  +   +S+S + ++L +  + ++ SVF PESG+  +K +T ++LL++++++  S  YK L S    +DK     F++  LK ++EYH  K+S  +E QT        L+EKLQ +D QF D   Q  +K + L E ++  ++R++E++LR EM  +++ FKD EI  IK  A++++ K L       E+  Q +  AL  RE+++ E   + ++ + +E Y QRQ +L+D+  ++ RE ++K+  E  E   ++ +E+HK     +  +   +K  E   + K+  E+  Y+L  +   + +   +   E K +E+  +L  E   +   KEEL +      E++L           + +QN+ L ++++E       +    +      + LLKQ++                P  E +V   EL +A      E    E  ++AL K+L +EI+    L  Q+   +  V+ L+ Q+++ K
Sbjct:    8 FTVADVLSQDELRKKLYQTFKDRGILDTLKTQLRNQLIHELMHPVLSGELQPRSISVEGSS--LLIGASNSLVADHLQRCGYEYSLSVFFPESGLAKEKVFTMQDLLQLIKINPTSSLYKSLVS---GSDKENQKGFLMHFLKELAEYHQAKESCNMETQTSSTFNRDSLAEKLQLIDDQFADAYPQ-RIKFESL-EIKLNEYKREIEEQLRAEMCQKLKFFKDTEIAKIKMEAKKKYEKELTMFQNDFEKACQAKSEALVLREKSTLERIHKHQEIETKEIYAQRQLLLKDMDLLRGREAELKQRVEAFELNQKLQEEKHKSITEALRRQEQNIKSFEETYDRKLKNELLKYQLELKDDYIIRTNRLIEDERKNKEKAVHLQEELIAINSKKEELNQSVNRVKELELELESVKAQSLAITKQNHMLNEKVKEMSDYSLLKEEKLELLAQ--NKLLKQQLEESRNENLRLLNRLAQPAPELAVFQKELRKAEKAIVVEHEEFESCRQALHKQLQDEIEHSAQLKAQILGYKASVKSLTTQVADLK 543

[Close]

BLAST of OFD1 vs. Ensembl Human
Match: OFD1 (OFD1 centriole and centriolar satellite protein [Source:HGNC Symbol;Acc:HGNC:2567])

HSP 1 Score: 133.265 bits (334), Expect = 5.345e-31
Identity = 149/533 (27.95%), Postives = 267/533 (50.09%), Query Frame = 3

Query:   72 YSTKSVKTDLNFQNKLLKLMKEKGVVDKLKTQVRQNLISEIAAKESIFNLKNNSNDKPEKSFDIFYHSSSSAIYEYLDKNNFHFTKSVFVPESGIKNDKFYTAEELLRVLQLDKNSEFYKKLQSDLLNTDK----SFILCLLKTISEYHTFKQS-EIEIQTDKPEKFIPLSEKLQKLDLQFEDRQKQGTLKTQQLYEDRIVAFQRDMEKRLRQEMENEIQRFKDHEILSIKRNAEEEFNKALKSKLKIMEEEYQNRLAALKDRERASQENHQQFKDSQERENYFQRQQILRDLSNIQERELQMKKEKEHLEREFEMMKEQHKIKLNQVEERNSKLKELEMGINMKITQEVNSYKLNEEKRLVQKWKEVEVFEMKLQEEKKYLDSEKCTVEKLKEELTKRQYLFNE--MDLISYP-------VLKQQNNSLLDQIEEFKXXXXXXXXXXXXDKHRISCLLKQKMGPNFEQSVLSNELERARDIFKRERSVLEEQKEALEKRLLEEIKSKRILTDQLSQQQDLVEMLSRQISENK 1628
            ++   V +    + KL +  K++G++D LKTQ+R  LI E+        L+  S      S  +   +S+S + ++L +  + ++ SVF PESG+  +K +T ++LL++++++  S  YK L S    +DK     F++  LK ++EYH  K+S  +E QT        L+EKLQ +D QF D   Q  +K + L E ++  ++R++E++LR EM  +++ FKD EI  IK  A++++ K L       E+  Q +  AL  RE+++ E   + ++ + +E Y QRQ +L+D+  ++ RE ++K+  E  E     +K+ + I+ N++ E   K KE  + +  ++   +NS K  E  + V + KE+E            L+ E    + L   +TK+ ++ NE   ++  Y         L  QN  L  Q+EE + +  +              LL +   P  E +V   EL +A      E    E  ++AL K+L +EI+    L  Q+   +  V+ L+ Q+++ K
Sbjct:    8 FTVADVLSQDELRKKLYQTFKDRGILDTLKTQLRNQLIHELMHPVLSGELQPRSISVEGSS--LLIGASNSLVADHLQRCGYEYSLSVFFPESGLAKEKVFTMQDLLQLIKINPTSSLYKSLVS---GSDKENQKGFLMHFLKELAEYHQAKESCNMETQTSSTFNRDSLAEKLQLIDDQFADAYPQ-RIKFESL-EIKLNEYKREIEEQLRAEMCQKLKFFKDTEIAKIKMEAKKKYEKELTMFQNDFEKACQAKSEALVLREKSTLERIHKHQEIETKEIYAQRQLLLKDMDLLRGREAELKQRVEAFELYQLELKDDYIIRTNRLIEDERKNKEKAVHLQEELIA-INSKK-EELNQSVNRVKELE------------LELESVKAQSLA--ITKQNHMLNEKVKEMSDYSLLKEEKLELLAQNKLLKQQLEESRNENLR--------------LLNRLAQPAPELAVFQKELRKAEKAIVVEHEEFESCRQALHKQLQDEIEHSAQLKAQILGYKASVKSLTTQVADLK 503

[Close]

BLAST of OFD1 vs. Ensembl Human
Match: OFD1 (OFD1 centriole and centriolar satellite protein [Source:HGNC Symbol;Acc:HGNC:2567])

HSP 1 Score: 77.411 bits (189), Expect = 8.618e-14
Identity = 106/405 (26.17%), Postives = 195/405 (48.15%), Query Frame = 3

Query:  480 LLKTISEYHTFKQS-EIEIQTDKPEKFIPLSEKLQKLDLQFEDRQKQGTLKTQQLYEDRIVAFQRDMEKRLRQEMENEIQRFKDHEILSIKRNAEEEFNKALKSKLKIMEEEYQNRLAALKDRERASQENHQQFKDSQERENYFQRQQILRDLSNIQERELQMKKEKEHLEREFEMMKEQHKIKLNQVEERNSKLKELEMGINMKITQEVNSYKLNEEKRLVQKWKEVEVFEMKLQEEKKYLDSEKCTVEKLKEELTKRQYLFNEMDL------ISYPVLKQQNNSLLDQIEEFKXXXXXXXXXXXXDKHRISCLLKQKM---------------GPNFEQSVLSNELERARDIFKRERSVLEEQKEALEKRLLEEIKSKRILTDQLSQQQDLVEMLSRQISENK 1628
             LK ++EYH  K+S  +E QT        L+EKLQ +D QF D   Q  +K + L E ++  ++R++E++LR EM  +++ FKD EI  IK  A++++ K L       E+  Q +  AL  RE+++ E   + ++ + +E Y QRQ +L+D+  ++ RE ++K+  E  E   ++ +E+HK     +  +   +K  E   + K+  E+  Y+L  +   + +   +   E K +E+  +L  E   +   KEEL +      E++L           + +QN+ L ++++E       +    +      + LLKQ++                P  E +V   EL +A      E    E  ++AL K+L +EI+    L  Q+   +  V+ L+ Q+++ K
Sbjct:    3 FLKELAEYHQAKESCNMETQTSSTFNRDSLAEKLQLIDDQFADAYPQ-RIKFESL-EIKLNEYKREIEEQLRAEMCQKLKFFKDTEIAKIKMEAKKKYEKELTMFQNDFEKACQAKSEALVLREKSTLERIHKHQEIETKEIYAQRQLLLKDMDLLRGREAELKQRVEAFELNQKLQEEKHKSITEALRRQEQNIKSFEETYDRKLKNELLKYQLELKDDYIIRTNRLIEDERKNKEKAVHLQEELIAINSKKEELNQSVNRVKELELELESVKAQSLAITKQNHMLNEKVKEMSDYSLLKEEKLELLAQ--NKLLKQQLEESRNENLRLLNRLAQPAPELAVFQKELRKAEKAIVVEHEEFESCRQALHKQLQDEIEHSAQLKAQILGYKASVKSLTTQVADLK 403

[Close]

BLAST of OFD1 vs. Ensembl Human
Match: OFD1 (OFD1 centriole and centriolar satellite protein [Source:HGNC Symbol;Acc:HGNC:2567])

HSP 1 Score: 70.8626 bits (172), Expect = 2.534e-12
Identity = 74/226 (32.74%), Postives = 127/226 (56.19%), Query Frame = 3

Query:  474 LCLLKTISEYHTFKQS-EIEIQTDKPEKFIPLSEKLQKLDLQFEDRQKQGTLKTQQLYEDRIVAFQRDMEKRLRQEMENEIQRFKDHEILSIKRNAEEEFNKALKSKLKIMEEEYQNRLAALKDRERASQENHQQFKDSQERENYFQRQQILRDLSNIQERELQMKKEKEHLEREFEMMKEQHKIKLNQV--EERNSK-----LKELEMGINMK---ITQEVNSYK 1118
            LC+ K ++EYH  K+S  +E QT        L+EKLQ +D QF D   Q  +K + L E ++  ++R++E++LR EM  +++ FKD EI  IK  A++++ K L       E+  Q +  AL  RE+++ E   + ++ + +E Y QRQ +L+D+  ++ RE ++K+  E  E     +K+ + I+ N++  +ER +K     L+E  + IN K   + Q VN  K
Sbjct:    4 LCIFKELAEYHQAKESCNMETQTSSTFNRDSLAEKLQLIDDQFADAYPQR-IKFESL-EIKLNEYKREIEEQLRAEMCQKLKFFKDTEIAKIKMEAKKKYEKELTMFQNDFEKACQAKSEALVLREKSTLERIHKHQEIETKEIYAQRQLLLKDMDLLRGREAELKQRVEAFELYQLELKDDYIIRTNRLIEDERKNKEKAVHLQEELIAINSKKEELNQSVNRVK 227

[Close]

BLAST of OFD1 vs. Ensembl Zebrafish
Match: ofd1 (OFD1 centriole and centriolar satellite protein [Source:NCBI gene;Acc:327216])

HSP 1 Score: 114.775 bits (286), Expect = 1.602e-25
Identity = 125/515 (24.27%), Postives = 256/515 (49.71%), Query Frame = 3

Query:  105 FQNKLLKLMKEKGVVDKLKTQVRQNLISEIAAKESIFNLKNNSNDKPEKSFDIFYHSSSSAIYEYLDKNNFHFTKSVFVPESGIKNDKFYTAEELLRVLQLDKNSEFYKKLQSDLLNTDKSFILCLLKTISEYHTFKQ-SEIEIQTDKPEKFI-PLSEKLQKLDLQFEDRQKQGTLKTQQLYEDRIVAFQRDMEKRLRQEMENEIQRFKDHEILSIKRNAEEEFNKALKSKLKIMEEEYQNRLAALKDRERASQENHQQFKDSQERENYFQRQQILRDLSNIQERELQMKKEKEHLEREFEMMKEQHKIKLNQVEERNSKLKELEMGINMKITQEVNSYK--LNEE-----KRLVQKWKEVEVFEMKLQEEKKYLDSEKCTVEKLKEELTKRQYLFN-EMDLISYPVLKQQNNSLLDQIEEFKXXXXXXXXXXXXDKHRISCLLKQKM---------------GPNFEQSVLSNELERARDIFKRERSVLEEQKEALEKRLLEEIKSKRILTDQL 1574
             + KL +  K +G++D LKTQ+R  LI E+ A   +   ++ S    + +  +   + +S + ++L    + +T SVF PE G+  DK  ++ ++L+++++  +   YK L S++ +    F+  LL  ++++  ++  S+   QT         L EK+Q +D ++E  + +G        E ++  ++++++++ + E+  ++Q F D EI  +K+  +E   K +    + ME+ Y+ +  AL  RE+ + E  Q+ ++ +E++ Y QRQ +LR++ +++ RE+++++  E  ++   + +E+ K   + +  R   +K +E     K+  E+  Y+  L EE     ++L +  + +     +LQ+E   ++++    E+   E+  +Q L   E       +LKQQ   L +Q+E  +   + +    +    RIS LLKQ++                P+ E  +L  EL R     K E+  LE QK  L  +L  E++   +L  QL
Sbjct:   14 MRQKLYQTFKSRGLLDTLKTQLRNQLIQELQA--PVRRGESASRRSADHTDSVLVSACNSVVVDHLRSAGYEYTLSVFQPECGLSKDKVLSSRDVLQIMKISPHMPLYKSLVSNIQSGQSGFLKSLLMELTDHSVYRDCSDNSTQTTSIAAHKESLVEKMQLIDEEYEVLRHRGDRWAS--VEAKLAEYRKEIQEQAQIELNAKLQHFMDVEIAKVKQEEKERSRKEILELRRDMEKTYELKSEALISREKNAIERLQKHQEIEEKDIYAQRQAVLREIESVRSREMELRQRMEAFDKSCALHEEKVKTMEDLLRRRELSVKTMEDSFEQKLKSELLKYQLELKEENMKRTEKLTENEERIRAEATRLQKEAAVIEAKTQDYERTSSEV--KQLLMELESSRSQASLLKQQKELLREQLENMRDYPELKKHTLELQT-RIS-LLKQQLEEKQQHNQRLTQELSAPSHEHLMLQAELRRLEAEHKLEKEELETQKNVLHTQLQHEVQQCALLKTQL 520

[Close]

BLAST of OFD1 vs. Ensembl Xenopus
Match: OFD1 (OFD1 centriole and centriolar satellite protein [Source:HGNC Symbol;Acc:HGNC:2567])

HSP 1 Score: 107.071 bits (266), Expect = 4.123e-23
Identity = 170/698 (24.36%), Postives = 323/698 (46.28%), Query Frame = 3

Query:  162 TQVRQNLISEIAAKESIFNLKNNSNDKPEKSFDIFYHSSSSAIYEYLDKNNFHFTKSVFVPESGIKNDKFYTAEELLRVLQLDKNSEFYKKLQSDLLNTDKSFILCLLKTISEYHTFKQSEIEIQTDKPEKFIPLSEKLQKLDLQFED----RQKQGTLKTQQLYEDRIVAFQRDMEKRLRQEMENEIQRFKDHEILSIKRNAEEEFNKALKSKLKIMEEEYQNRLAALKDRERASQENHQQFKDSQERENYFQRQQILRDLSNIQERELQMKKEKEHLEREFEMMKEQHKIKLNQVEERNSKLKELEMGINMKITQEV--NSYKLNEE-----KRLVQKWKEVEVFEMKLQEEKKYLDSEKCTVE----KLKEELTKRQYLFNEMDLISYPVLKQQNNSLLDQI-----------EEFKXXXXXXXXXXXXDK-HRISCLLKQK-MGPNFEQSVLSNELERARDIFKRERSVLEEQKEALEKRLLEEIKSKRILTDQLSQQQDLVEMLSRQISENKDLSYRNKCGFISSRSQNYGPYSNRNP-PTNRDSS-----------PHSPTDR-----RRRLSNFESATNE----FLHEVDEYNLPMDVE-DLTTDAKHKLMNLDEETEQINKAYFEFKNRMANSFSKIGEFHVELHPELVSK--SFKNGIEEGRRLKKTKSNELPIFFDSNSRTASFPMDN 2099
            TQ+R  LI E+  K   FN +     +  +S  + + +S+S + ++L K  + ++ SVF PE G++ +K +T  + L +L+++ NS+ YK L +       S +  L+K                 D+                QFED    R+K  +L      E +I  ++R+ME++LR EM  ++Q FKD EI  IK    E+  + +    + +E+ YQ +L  L  RE+ + E  Q+ ++ + +E Y QRQ +L+D+  ++ RE  +++  E  ER  ++  E+++     + +R  ++K +E   + K+  E+  +  +LNEE     K++ +  +  +V   KL+EE   ++ +K   E    ++KE   +   L  +M L++     +QN+ L D++           E+ K Q + +    Q D+ H+ + +L+++ + P+ E  VL  EL+R     K ++   + QKE LE +L  E+K    L  QL   +D  + L+ ++   + L ++ +   ++  ++ Y     RNP P+  D S           P    D+      R    F  A       + H     +   D + +   + K ++  L++E E + +AY +++NR++   +  G     +H   VSK  S  + + + +R  K       I  D + +  +F  DN
Sbjct:   30 TQLRNQLIHEL--KYPTFNGEPVCYLEALESDSLLHRASNSMVADHLRKCGYEYSLSVFYPECGLEKEKMFTVHDFLHLLKINPNSQLYKSLVT-------SIVALLVKCFFLIFFIFLLIKLKFIDE----------------QFEDIYPKRKKFESL------ESKISDYRREMEEQLRTEMAQKLQHFKDVEIAKIKLEETEKSQREMSDFRRELEKTYQTKLEGLVSREKNAIERLQRQQEIEAKEIYSQRQSLLKDIDIVRARESDLRQRMEAFERTQKLEAEKNRSIDEFLRKRELEVKNIEDTFDQKLKNELLRHQIELNEEYIKRTKKVSEDERRNKVEASKLREEAVVINMKKHESEQAMTRIKELEIEVDSLRAQMSLVT-----RQNHHLTDKLKETVDYPLVHEEKLKLQGEVKILKQQLDEIHKDNQILRERNLHPSPEYLVLQEELKRMESARKMDQEEFKSQKEILETQLHSEVKRSAELKAQLLNNEDSAQKLNSKV---EHLEFQLRQAQLALENEVY-----RNPKPSLVDRSVLDFTADKIVPPDIYVDKAVLKSHRSYDTFVEACGRSSPMYCHTTRPRSSSPDSDFEFVANTKARIKELEKEAEYLEEAYRKYQNRISEGATIEG-----IHLTTVSKESSLLSTVPKTKRSVK-------ILTDVSHQKVAFLEDN 671

[Close]

BLAST of OFD1 vs. Ensembl Xenopus
Match: OFD1 (OFD1 centriole and centriolar satellite protein [Source:HGNC Symbol;Acc:HGNC:2567])

HSP 1 Score: 75.0998 bits (183), Expect = 2.956e-13
Identity = 131/554 (23.65%), Postives = 261/554 (47.11%), Query Frame = 3

Query:  564 LSEKLQKLDLQFED----RQKQGTLKTQQLYEDRIVAFQRDMEKRLRQEMENEIQRFKDHEILSIKRNAEEEFNKALKSKLKIMEEEYQNRLAALKDRERASQENHQQFKDSQERENYFQRQQILRDLSNIQERELQMKKEKEHLEREFEMMKEQHKIKLNQVEERNSKLKELEMGINMKITQEVNSYKLNEEKRLVQKWKE-----VEVFEMKLQEEKKYLDSEK---CTVEKLKEE--LTKRQ--YLFNEM-DLISYPVLKQQNNSLLDQIEEFKXXXXXXXXXXXXDKHRISCLLKQK-MGPNFEQSVLSNELERARDIFKRERSVLEEQKEALEKRLLEEIKSKRILTDQLSQQQDLVEMLSRQISENKDLSYRNKCGFISSRSQNYGPYSNRNP-PTNRDSS-----------PHSPTDR-----RRRLSNFESATNE----FLHEVDEYNLPMDVE-DLTTDAKHKLMNLDEETEQINKAYFEFKNRMANSFSKIGEFHVELHPELVSK--SFKNGIEEGRRLKKTKSNELPIFFDSNSRTASFPMDN 2099
            + EKL+ +D QFED    R+K  +L      E +I  ++R+ME++LR EM  ++Q FKD EI  IK    E+  + +    + +E+ YQ +L  L  RE+ + E  Q+ ++ + +E Y QRQ +L+D+  ++ RE  +++  E  ER  ++  E+++     + +R  ++K +E   + K+  E+  +++   +  +++ K+       V  MK  E ++ +   K     V+ L+ +  L  RQ  +L +++ + + YP++ ++   L  +++  K            + H+ + +L+++ + P+ E  VL  EL+R     K ++   + QKE LE +L  E+K    L  QL   +D  + L+ ++   + L ++ +   ++  ++ Y     RNP P+  D S           P    D+      R    F  A       + H     +   D + +   + K ++  L++E E + +AY +++NR++   +  G     +H   VSK  S  + + + +R  K       I  D + +  +F  DN
Sbjct:   15 VVEKLKFIDEQFEDIYPKRKKFESL------ESKISDYRREMEEQLRTEMAQKLQHFKDVEIAKIKLEETEKSQREMSDFRRELEKTYQTKLEGLVSREKNAIERLQRQQEIEAKEIYSQRQSLLKDIDIVRARESDLRQRMEAFERTQKLEAEKNRSIDEFLRKRELEVKNIEDTFDQKLKNELLRHQIELNEEYIKRTKKNHNQHAVVINMKKHESEQAMTRIKELEIEVDSLRAQMSLVTRQNHHLTDKLKETVDYPLVHEEKLKLQGEVKILK--------QQLDEIHKDNQILRERNLHPSPEYLVLQEELKRMESARKMDQEEFKSQKEILETQLHSEVKRSAELKAQLLNNEDSAQKLNSKV---EHLEFQLRQAQLALENEVY-----RNPKPSLVDRSVLDFTADKIVPPDIYVDKAVLKSHRSYDTFVEACGRSSPMYCHTTRPRSSSPDSDFEFVANTKARIKELEKEAEYLEEAYRKYQNRISEGATIEG-----IHLTTVSKESSLLSTVPKTKRSVK-------ILTDVSHQKVAFLEDN 534

[Close]

BLAST of OFD1 vs. Ensembl Mouse
Match: Ofd1 (OFD1, centriole and centriolar satellite protein [Source:MGI Symbol;Acc:MGI:1350328])

HSP 1 Score: 132.494 bits (332), Expect = 6.902e-31
Identity = 162/653 (24.81%), Postives = 321/653 (49.16%), Query Frame = 3

Query:  105 FQNKLLKLMKEKGVVDKLKTQVRQNLISEIAAKESIFNLKNNSNDKPEKSFD---IFYHSSSSAIYEYLDKNNFHFTKSVFVPESGIKNDKFYTAEELLRVLQLDKNSEFYKKLQSDLLNTD-KSFILCLLKTISEYHTFKQS---EIEIQTDKPEKFIPLSEKLQKLDLQFED----RQKQGTLKTQQLYEDRIVAFQRDMEKRLRQEMENEIQRFKDHEILSIKRNAEEEFNKALKSKLKIMEEEYQNRLAALKDRERASQENHQQFKDSQERENYFQRQQILRDLSNIQERELQMKKEKEHLEREFEMMKEQHKIKLNQVEERNSKLKELEMGINMKITQEVNSYKLNEEKRLVQKWKEVEVFEMKLQEEKKYLDSEKCTVEKLKEELTKRQYLFNEMDL------ISYPVLKQQNNSLLDQIEE------FKXXXXXXXXXXXXDKHRIS-------CLLKQKMGPNFEQSVLSNELERARDIFKRERSVLEEQKEALEKRLLEEIKSKRILTDQLSQQQDLVEMLSRQISENKDL-----------SYRN-KCGFISSRSQNYGPYSNRNPPTNRDSSP---HSPTDRRRRLSN-FESATNEFLHEVDEYNLP-MDVEDLTTDAKHKLMNLDEETEQINKAYFEFKNR 1922
             + KL +  K++GV+D L+TQ+R  LI E+     +  + +     P  S +   +   +S+S + ++L +  + ++ SVF PESG+  +K +T ++LL++++++ +S  YK L S     + K F++  LK ++EY+  K+S   E +  T  P + + L+EK Q +D QF D    R K  +L+T      ++  ++++++ +L+ EM ++++ F++ EI  +K     ++ K L       E   Q +  AL  +E+ S E  ++ ++ + +E Y QRQ +L D++ ++ RE ++K+  E  E   ++ +E+ K +   +E R   LK +E   + K+  E+  Y+L  +   + +  ++   E K +E+  +L  E   +   KEEL+K      E++L        +  + +QN+ L +++ E       K++  +  + N+  K ++         LL +   P  E  +   EL++     + E    E  ++ALEK+L  EI++   L  Q+++    V+ L+ Q++E K              YRN K   I S S      S +  P + D S    + P ++ + ++    S    +++   E + P  D E + +  K K+  L++E E++ KA+  +  R
Sbjct:   20 LRKKLYQTFKDRGVLDTLQTQLRNQLIHEL-----MHPVLSGEVKPPSISVEGSALLIGASNSLVADHLQRCGYEYSLSVFFPESGLAKEKIFTMQDLLQLIRINPSSSLYKSLISGFDKENKKGFLMSFLKELAEYYQAKESCDAETQTSTTFPSQ-VSLAEKFQLIDAQFADGFPHRSKLESLET------KLNEYKKEVQHQLQVEMCHKLKYFREAEITKVKMEERRKYEKELAEFQNEFERTCQAKNEALISQEKNSLERIKKHREMESKEIYAQRQLLLNDIALLRGREAELKERIETFELTQKLQEEKIKSEAEALERREQNLKNIEDTYDQKLKTELLKYQLELKDDYITRTNKLLEEERKNKEKTIHLQEELTVINSKKEELSKSVKHMKEVELELESVKAQFLAISKQNHLLNEKVREMSDYSQLKEEKVELQAQNKLLKLQLEETRNENLRLLDRITQPPPELVIFQKELQKTEKAMELEHKDFETHRQALEKQLQSEIENSAQLRTQIAEYDASVKRLTVQVAELKSQLKQTQIALENEVYRNPKHSLIHSLSGLL--LSGKMAPHSEDKSGDFLNVPLEQNKVIAGAVMSRVPPYVNTATEASSPESDFEFIASSTKAKVRELEQEAERLEKAFRTYYQR 658

[Close]

BLAST of OFD1 vs. UniProt/SwissProt
Match: sp|O75665|OFD1_HUMAN (Oral-facial-digital syndrome 1 protein OS=Homo sapiens OX=9606 GN=OFD1 PE=1 SV=1)

HSP 1 Score: 136.732 bits (343), Expect = 1.811e-31
Identity = 145/545 (26.61%), Postives = 270/545 (49.54%), Query Frame = 3

Query:   72 YSTKSVKTDLNFQNKLLKLMKEKGVVDKLKTQVRQNLISEIAAKESIFNLKNNSNDKPEKSFDIFYHSSSSAIYEYLDKNNFHFTKSVFVPESGIKNDKFYTAEELLRVLQLDKNSEFYKKLQSDLLNTDK----SFILCLLKTISEYHTFKQS-EIEIQTDKPEKFIPLSEKLQKLDLQFEDRQKQGTLKTQQLYEDRIVAFQRDMEKRLRQEMENEIQRFKDHEILSIKRNAEEEFNKALKSKLKIMEEEYQNRLAALKDRERASQENHQQFKDSQERENYFQRQQILRDLSNIQERELQMKKEKEHLEREFEMMKEQHKIKLNQVEERNSKLKELEMGINMKITQEVNSYKLNEEKRLVQKWKEVEVFEMKLQEEKKYLDSEKCTVEKLKEELTKRQYLFNEMDL------ISYPVLKQQNNSLLDQIEEFKXXXXXXXXXXXXDKHRISCLLKQKM---------------GPNFEQSVLSNELERARDIFKRERSVLEEQKEALEKRLLEEIKSKRILTDQLSQQQDLVEMLSRQISENK 1628
            ++   V +    + KL +  K++G++D LKTQ+R  LI E+        L+  S      S  +   +S+S + ++L +  + ++ SVF PESG+  +K +T ++LL++++++  S  YK L S    +DK     F++  LK ++EYH  K+S  +E QT        L+EKLQ +D QF D   Q  +K + L E ++  ++R++E++LR EM  +++ FKD EI  IK  A++++ K L       E+  Q +  AL  RE+++ E   + ++ + +E Y QRQ +L+D+  ++ RE ++K+  E  E   ++ +E+HK     +  +   +K  E   + K+  E+  Y+L  +   + +   +   E K +E+  +L  E   +   KEEL +      E++L           + +QN+ L ++++E       +    +      + LLKQ++                P  E +V   EL +A      E    E  ++AL K+L +EI+    L  Q+   +  V+ L+ Q+++ K
Sbjct:    8 FTVADVLSQDELRKKLYQTFKDRGILDTLKTQLRNQLIHELMHPVLSGELQPRSISVEGSS--LLIGASNSLVADHLQRCGYEYSLSVFFPESGLAKEKVFTMQDLLQLIKINPTSSLYKSLVS---GSDKENQKGFLMHFLKELAEYHQAKESCNMETQTSSTFNRDSLAEKLQLIDDQFADAYPQ-RIKFESL-EIKLNEYKREIEEQLRAEMCQKLKFFKDTEIAKIKMEAKKKYEKELTMFQNDFEKACQAKSEALVLREKSTLERIHKHQEIETKEIYAQRQLLLKDMDLLRGREAELKQRVEAFELNQKLQEEKHKSITEALRRQEQNIKSFEETYDRKLKNELLKYQLELKDDYIIRTNRLIEDERKNKEKAVHLQEELIAINSKKEELNQSVNRVKELELELESVKAQSLAITKQNHMLNEKVKEMSDYSLLKEEKLELLAQ--NKLLKQQLEESRNENLRLLNRLAQPAPELAVFQKELRKAEKAIVVEHEEFESCRQALHKQLQDEIEHSAQLKAQILGYKASVKSLTTQVADLK 543

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BLAST of OFD1 vs. UniProt/SwissProt
Match: sp|Q80Z25|OFD1_MOUSE (Oral-facial-digital syndrome 1 protein homolog OS=Mus musculus OX=10090 GN=Ofd1 PE=1 SV=1)

HSP 1 Score: 132.109 bits (331), Expect = 5.161e-30
Identity = 162/653 (24.81%), Postives = 321/653 (49.16%), Query Frame = 3

Query:  105 FQNKLLKLMKEKGVVDKLKTQVRQNLISEIAAKESIFNLKNNSNDKPEKSFD---IFYHSSSSAIYEYLDKNNFHFTKSVFVPESGIKNDKFYTAEELLRVLQLDKNSEFYKKLQSDLLNTD-KSFILCLLKTISEYHTFKQS---EIEIQTDKPEKFIPLSEKLQKLDLQFED----RQKQGTLKTQQLYEDRIVAFQRDMEKRLRQEMENEIQRFKDHEILSIKRNAEEEFNKALKSKLKIMEEEYQNRLAALKDRERASQENHQQFKDSQERENYFQRQQILRDLSNIQERELQMKKEKEHLEREFEMMKEQHKIKLNQVEERNSKLKELEMGINMKITQEVNSYKLNEEKRLVQKWKEVEVFEMKLQEEKKYLDSEKCTVEKLKEELTKRQYLFNEMDL------ISYPVLKQQNNSLLDQIEE------FKXXXXXXXXXXXXDKHRIS-------CLLKQKMGPNFEQSVLSNELERARDIFKRERSVLEEQKEALEKRLLEEIKSKRILTDQLSQQQDLVEMLSRQISENKDL-----------SYRN-KCGFISSRSQNYGPYSNRNPPTNRDSSP---HSPTDRRRRLSN-FESATNEFLHEVDEYNLP-MDVEDLTTDAKHKLMNLDEETEQINKAYFEFKNR 1922
             + KL +  K++GV+D L+TQ+R  LI E+     +  + +     P  S +   +   +S+S + ++L +  + ++ SVF PESG+  +K +T ++LL++++++ +S  YK L S     + K F++  LK ++EY+  K+S   E +  T  P + + L+EK Q +D QF D    R K  +L+T      ++  ++++++ +L+ EM ++++ F++ EI  +K     ++ K L       E   Q +  AL  +E+ S E  ++ ++ + +E Y QRQ +L D++ ++ RE ++K+  E  E   ++ +E+ K +   +E R   LK +E   + K+  E+  Y+L  +   + +  ++   E K +E+  +L  E   +   KEEL+K      E++L        +  + +QN+ L +++ E       K++  +  + N+  K ++         LL +   P  E  +   EL++     + E    E  ++ALEK+L  EI++   L  Q+++    V+ L+ Q++E K              YRN K   I S S      S +  P + D S    + P ++ + ++    S    +++   E + P  D E + +  K K+  L++E E++ KA+  +  R
Sbjct:   18 LRKKLYQTFKDRGVLDTLQTQLRNQLIHEL-----MHPVLSGEVKPPSISVEGSALLIGASNSLVADHLQRCGYEYSLSVFFPESGLAKEKIFTMQDLLQLIRINPSSSLYKSLISGFDKENKKGFLMSFLKELAEYYQAKESCDAETQTSTTFPSQ-VSLAEKFQLIDAQFADGFPHRSKLESLET------KLNEYKKEVQHQLQVEMCHKLKYFREAEITKVKMEERRKYEKELAEFQNEFERTCQAKNEALISQEKNSLERIKKHREMESKEIYAQRQLLLNDIALLRGREAELKERIETFELTQKLQEEKIKSEAEALERREQNLKNIEDTYDQKLKTELLKYQLELKDDYITRTNKLLEEERKNKEKTIHLQEELTVINSKKEELSKSVKHMKEVELELESVKAQFLAISKQNHLLNEKVREMSDYSQLKEEKVELQAQNKLLKLQLEETRNENLRLLDRITQPPPELVIFQKELQKTEKAMELEHKDFETHRQALEKQLQSEIENSAQLRTQIAEYDASVKRLTVQVAELKSQLKQTQIALENEVYRNPKHSLIHSLSGLL--LSGKMAPHSEDKSGDFLNVPLEQNKVIAGAVMSRVPPYVNTATEASSPESDFEFIASSTKAKVRELEQEAERLEKAFRTYYQR 656

[Close]

BLAST of OFD1 vs. UniProt/SwissProt
Match: sp|Q7SZK7|OFD1_DANRE (Oral-facial-digital syndrome 1 protein homolog OS=Danio rerio OX=7955 GN=ofd1 PE=2 SV=1)

HSP 1 Score: 115.161 bits (287), Expect = 8.058e-25
Identity = 124/515 (24.08%), Postives = 254/515 (49.32%), Query Frame = 3

Query:  105 FQNKLLKLMKEKGVVDKLKTQVRQNLISEIAAKESIFNLKNNSNDKPEKSFDIFYHSSSSAIYEYLDKNNFHFTKSVFVPESGIKNDKFYTAEELLRVLQLDKNSEFYKKLQSDLLNTDKSFILCLLKTISEYHTFKQ-SEIEIQTDKPEKFI-PLSEKLQKLDLQFEDRQKQGTLKTQQLYEDRIVAFQRDMEKRLRQEMENEIQRFKDHEILSIKRNAEEEFNKALKSKLKIMEEEYQNRLAALKDRERASQENHQQFKDSQERENYFQRQQILRDLSNIQERELQMKKEKEHLEREFEMMKEQHKIKLNQVEERNSKLKELEMGINMKITQEVNSYKL-------NEEKRLVQKWKEVEVFEMKLQEEKKYLDSEKCTVEKLKEELTKRQYLFN-EMDLISYPVLKQQNNSLLDQIEEFKXXXXXXXXXXXXDKHRISCLLKQKM---------------GPNFEQSVLSNELERARDIFKRERSVLEEQKEALEKRLLEEIKSKRILTDQL 1574
             + KL +  K +G++D LKTQ+R  LI E+ A   +   ++ S    + +  +   + +S + ++L    + +T SVF PE G+  DK  ++ ++L+++++  +   YK L S++ +    F+  LL  ++++  ++  S+   QT         L EK+Q +D ++E  + +G        E ++  ++++++++ + E+  ++Q F D EI  +K+  +E   K +    + ME+ Y+ +  AL  RE+ + E  Q+ ++ +E++ Y QRQ +LR++ +++ RE+++++  E  ++   + +E+ K   + +  R   +K +E     K+  E+  Y+L          ++L +  + +     +LQ+E   +D++    E+   E+  +Q L   E       +LKQQ   L +Q+E  +   + +    +    RIS LLKQ++                P+ E  +L  EL R     K E+  LE QK  L  +L  E++   +L  QL
Sbjct:   14 MRQKLYQTFKSRGLLDTLKTQLRNQLIQELQA--PVRRGESASRRSADHTDSVLVSACNSVVVDHLRSAGYEYTLSVFQPECGLSKDKVLSSRDVLQIMKISPHMPLYKSLVSNIQSGQSGFLKSLLMELTDHSVYRDCSDNSTQTTSIAAHKESLVEKMQLIDEEYEVLRHRGDRWAS--VEAKLAEYRKEIQEQAQIELNAKLQHFMDVEIAKVKQEEKERSRKEILELRRDMEKTYELKSEALISREKNAIERLQKHQEIEEKDIYAQRQAVLREIESVRSREMELRQRMEAFDKSCALHEEKVKTMEDLLRRRELSVKTMEDSFEQKLKSELLKYQLELKEENMKRPEKLTENEERIRAEAARLQKEAAVVDAKTEDYERKSSEV--KQLLMELESSRSQASLLKQQKELLREQLENMRDYPELKKHTLELQT-RIS-LLKQQLEEKQQHNQRLTQELSAPSHEHLMLQAELRRLEAEHKLEKEELETQKNVLHTQLQHEVQQCALLKTQL 520

[Close]

BLAST of OFD1 vs. TrEMBL
Match: H6WA38 (OFD1 (Fragment) OS=Schmidtea mediterranea OX=79327 PE=2 SV=1)

HSP 1 Score: 393.275 bits (1009), Expect = 5.800e-128
Identity = 193/197 (97.97%), Postives = 196/197 (99.49%), Query Frame = 3

Query:  132 KEKGVVDKLKTQVRQNLISEIAAKESIFNLKNNSNDKPEKSFDIFYHSSSSAIYEYLDKNNFHFTKSVFVPESGIKNDKFYTAEELLRVLQLDKNSEFYKKLQSDLLNTDKSFILCLLKTISEYHTFKQSEIEIQTDKPEKFIPLSEKLQKLDLQFEDRQKQGTLKTQQLYEDRIVAFQRDMEKRLRQEMENEIQRF 722
            KEKGVVDKLKTQVRQNLISEIAAKESIFNLKNNSNDKPEKSFDIFYHSSSSAIYEYLDKNNFHFTKSVFVPESGIKNDKFYTAEELLRVLQLDKNSEFYKKLQSDLLNTDKSFILCLLKTISEYHTFKQSEIEIQTDKPEKFIPLSEKLQKLDLQFEDRQKQGTLKTQQLYEDRIVAFQRDMEKRLRQEMENE++ +
Sbjct:    1 KEKGVVDKLKTQVRQNLISEIAAKESIFNLKNNSNDKPEKSFDIFYHSSSSAIYEYLDKNNFHFTKSVFVPESGIKNDKFYTAEELLRVLQLDKNSEFYKKLQSDLLNTDKSFILCLLKTISEYHTFKQSEIEIQTDKPEKFIPLSEKLQKLDLQFEDRQKQGTLKTQQLYEDRIVAFQRDMEKRLRQEMENEVEYY 197

[Close]

BLAST of OFD1 vs. TrEMBL
Match: A0A2C9KXQ8 (LisH domain-containing protein OS=Biomphalaria glabrata OX=6526 GN=106068128 PE=4 SV=1)

HSP 1 Score: 207.223 bits (526), Expect = 1.704e-51
Identity = 191/721 (26.49%), Postives = 367/721 (50.90%), Query Frame = 3

Query:  105 FQNKLLKLMKEKGVVDKLKTQVRQNLISEIAAKESIFN-LKNNSNDKPEKSFDIFYHSSSSAIYEYLDKNNFHFTKSVFVPESGIKNDKFYTAEELLRVLQLDKNSEFYKKLQSDLL-NTDKSFILCLLKTISEYHTFKQSEIEIQTD--KPEKFIPLSEKLQKLDLQFEDRQKQGTLKTQQLYEDRIVAFQRDMEKRLRQEMENEIQRFKDHEILSIKRNAEEEFNKALKSKLKIMEEEYQNRLAALKDRERASQENHQQFKDSQERENYFQRQQILRDLSNIQERELQMKKEKEHLEREFEMMKEQHKIKLNQVEERNSKLKELEMGINMKITQEVNSYKLNEEKRLVQKWKEVEVFEMKLQEEKKYLDSEKCTVEKLKEELTKRQYLFNEM--------------------------DLISYPVLKQQNNSLLDQIEEFKXXXXXXXXXXXXDKHRISCLLKQKMGPNFEQSVLSNELERARDIFKRERSVLEEQKEALEKRLLEEIKSKRILTDQLSQQQDLVEMLSRQISE------------NKDLSYRNKCG-----FISSRSQNYGPYSNRNPPTNRDSSPHSPTDRRRRLSNFESATNEFLHEVDEYNL--------------PMDVEDLTTDAKHKLMNLDEETEQINKAYFEFKNRMANSFSKIGEFHVELHPELVSKSFKNGIEEGRRLKKTKSNELPIFFDSNSRTAS 2084
             +N+L   ++ +G VD +K+Q+R +L++E+  ++++   L     + PE+   + + +S+S +  +L    + +T SVF+PESG+  DK + A +LL++L +   S  Y++L ++   ++ + F+   +  +S  H    + +  QTD  K     PL EKL  +D  +  R++      +   E+R+++FQR +E R   +++ E+ R K+ EI +IK + +E   K L+   + ME  Y++R  AL  RER + E  QQ  + QERE Y QRQ IL ++  +++RE+++K+E E  +RE  + +E+ K K  ++  R  ++K+ E     ++  E+  +KL+++ R +++ + VEV E  L+E+++ L  EK  ++++K+EL  +    NE+                          D+  Y  LK+Q     +++E  + +L +  S+N++++ R   LL++   P+ E  +L  +LERA++  ++E+ V  +QK+ LE RL EE+   + L  +  +Q   ++ ++R+I +            N ++  + K G      + SR  +    S+R+   + +   H P    +R S F++   E  H VD                   +D  D+   AK++L +LD+E   + KAY +F  R+ N    I    ++   +   +S   G ++G  +  T   + PI FD N R+++
Sbjct:   13 LRNRLYHSLRNRGFVDSIKSQLRNSLVTEL--QQTVHGPLTLKDLNIPEEG-SLLHRASNSLVANHLSACQYEYTLSVFLPESGLSQDKKFEALDLLKLLNISPLSRLYQRLIAETHKDSKRGFLWQGVSEVSSLHANSINTVGCQTDLIKVGPITPLDEKLSDVDEMYASRREDYLRTGRAGAEERLLSFQRQLEDRYNTQLKMELARMKESEIATIKLSEKENSRKTLEQAKRDMERIYKDRYDALVIRERNTMERLQQQTEMQEREIYAQRQSILEEIEAVRQREVEVKREAEVNKREKRLSEERVKDKETELRRREMEIKQRESSFEQRLQNEMAQFKLDQQARFIERVQNVEVREQTLKEQERILSEEKFRLQQIKDELRDKTQRVNELETKLSECKYSEVNANKNNEYLNAKLRDMSDYSTLKEQVVLYRNELETLRTRLAEVLSMNERERGRQEELLRELRRPSPESLMLQRDLERAKESLRQEQIVFNQQKQVLEARLKEELDCNKDLMARFEEQTLQMKEMNREIVDLRQHLHMTTKALNNEVYRKAKEGLEQSQLVESRLSHKVHDSSRH-SVDLNFDDHEP----QRPSRFDADPKEIYHGVDFETFSQVRDGLYFEDDISSIDSADVIAQAKYRLKSLDQEAHNLEKAYHDFHCRITN----IHAIPLDQPAQSPPRSRVVGQQQGAIV--TSPAQSPIPFD-NPRSST 718

[Close]

BLAST of OFD1 vs. TrEMBL
Match: A0A2C9KXP3 (LisH domain-containing protein OS=Biomphalaria glabrata OX=6526 GN=106068128 PE=4 SV=1)

HSP 1 Score: 206.838 bits (525), Expect = 2.401e-51
Identity = 191/721 (26.49%), Postives = 367/721 (50.90%), Query Frame = 3

Query:  105 FQNKLLKLMKEKGVVDKLKTQVRQNLISEIAAKESIFN-LKNNSNDKPEKSFDIFYHSSSSAIYEYLDKNNFHFTKSVFVPESGIKNDKFYTAEELLRVLQLDKNSEFYKKLQSDLL-NTDKSFILCLLKTISEYHTFKQSEIEIQTD--KPEKFIPLSEKLQKLDLQFEDRQKQGTLKTQQLYEDRIVAFQRDMEKRLRQEMENEIQRFKDHEILSIKRNAEEEFNKALKSKLKIMEEEYQNRLAALKDRERASQENHQQFKDSQERENYFQRQQILRDLSNIQERELQMKKEKEHLEREFEMMKEQHKIKLNQVEERNSKLKELEMGINMKITQEVNSYKLNEEKRLVQKWKEVEVFEMKLQEEKKYLDSEKCTVEKLKEELTKRQYLFNEM--------------------------DLISYPVLKQQNNSLLDQIEEFKXXXXXXXXXXXXDKHRISCLLKQKMGPNFEQSVLSNELERARDIFKRERSVLEEQKEALEKRLLEEIKSKRILTDQLSQQQDLVEMLSRQISE------------NKDLSYRNKCG-----FISSRSQNYGPYSNRNPPTNRDSSPHSPTDRRRRLSNFESATNEFLHEVDEYNL--------------PMDVEDLTTDAKHKLMNLDEETEQINKAYFEFKNRMANSFSKIGEFHVELHPELVSKSFKNGIEEGRRLKKTKSNELPIFFDSNSRTAS 2084
             +N+L   ++ +G VD +K+Q+R +L++E+  ++++   L     + PE+   + + +S+S +  +L    + +T SVF+PESG+  DK + A +LL++L +   S  Y++L ++   ++ + F+   +  +S  H    + +  QTD  K     PL EKL  +D  +  R++      +   E+R+++FQR +E R   +++ E+ R K+ EI +IK + +E   K L+   + ME  Y++R  AL  RER + E  QQ  + QERE Y QRQ IL ++  +++RE+++K+E E  +RE  + +E+ K K  ++  R  ++K+ E     ++  E+  +KL+++ R +++ + VEV E  L+E+++ L  EK  ++++K+EL  +    NE+                          D+  Y  LK+Q     +++E  + +L +  S+N++++ R   LL++   P+ E  +L  +LERA++  ++E+ V  +QK+ LE RL EE+   + L  +  +Q   ++ ++R+I +            N ++  + K G      + SR  +    S+R+   + +   H P    +R S F++   E  H VD                   +D  D+   AK++L +LD+E   + KAY +F  R+ N    I    ++   +   +S   G ++G  +  T   + PI FD N R+++
Sbjct:   13 LRNRLYHSLRNRGFVDSIKSQLRNSLVTEL--QQTVHGPLTLKDLNIPEEG-SLLHRASNSLVANHLSACQYEYTLSVFLPESGLSQDKKFEALDLLKLLNISPLSRLYQRLIAETHKDSKRGFLWQGVSEVSSLHANSINTVGCQTDLIKVGPITPLDEKLSDVDEMYASRREDYLRTGRAGAEERLLSFQRQLEDRYNTQLKMELARMKESEIATIKLSEKENSRKTLEQAKRDMERIYKDRYDALVIRERNTMERLQQQTEMQEREIYAQRQSILEEIEAVRQREVEVKREAEVNKREKRLSEERVKDKETELRRREMEIKQRESSFEQRLQNEMAQFKLDQQARFIERVQNVEVREQTLKEQERILSEEKFRLQQIKDELRDKTQRVNELETKLSECKYSEVNANKNNEYLNAKLRDMSDYSTLKEQVVLYRNELETLRTRLAEVLSMNERERGRQEELLRELRRPSPESLMLQRDLERAKESLRQEQIVFNQQKQVLEARLKEELDCNKDLMARFEEQTLQMKEMNREIVDLRQHLHMTTKALNNEVYRKAKEGLEQSQLVESRLSHKVHDSSRH-SVDLNFDDHEP----QRPSRFDADPKEIYHGVDFETFSQVRDGLYFEDDISSIDSADVIAQAKYRLKSLDQEAHNLEKAYHDFHCRITN----IHAIPLDQPAQSPPRSRVVGQQQGAIV--TSPAQSPIPFD-NPRSST 718

[Close]

BLAST of OFD1 vs. TrEMBL
Match: A0A3S1C016 (LisH domain-containing protein OS=Elysia chlorotica OX=188477 GN=EGW08_012949 PE=4 SV=1)

HSP 1 Score: 206.068 bits (523), Expect = 4.857e-51
Identity = 179/686 (26.09%), Postives = 346/686 (50.44%), Query Frame = 3

Query:  105 FQNKLLKLMKEKGVVDKLKTQVRQNLISEIAAK-ESIFNLKNNSNDKPEKSFDIFYHSSSSAIYEYLDKNNFHFTKSVFVPESGIKNDKFYTAEELLRVLQLDKNSEFYKKLQSDLL-NTDKSFILCLLKTISEYHTFKQSEIEIQTD--KPEKFIPLSEKLQKLDLQFEDRQKQGTLKTQQLYEDRIVAFQRDMEKRLRQEMENEIQRFKDHEILSIKRNAEEEFNKALKSKLKIMEEEYQNRLAALKDRERASQENHQQFKDSQERENYFQRQQILRDLSNIQERELQMKKEKEHLEREFEMMKEQHKIKLNQVEERNSKLKELEMGINMKITQEVNSYKLNEEKRLVQKWKEVEVFEMKLQEEKKYLDSEKCTVEKLKEELTKRQYLFNEM--------------------------DLISYPVLKQQNNSLLDQIEEFKXXXXXXXXXXXXDKHRISCLLKQKMGPNFEQSVLSNELERARDIFKRERSVLEEQKEALEKRLLEEIKSKRILTDQLSQQQDLVEMLSRQISENKD---LSYR------------NKCGFISSRSQNYG---PYSNRNPPTNRDSSPHSPTDRRRRLSNFESA-------------TNEFLHEVDEYNLPM----------------DVEDLTTDAKHKLMNLDEETEQINKAYFEFKNRMAN 1931
             +N+L   ++ +G+VD +K+Q+R +L++E+         LK+     PE+   + + +S+S +  +L    + ++ SVF+PE G+  DK +   +LL++L +   S  Y++L S    ++ K F+  LL  +S  H    + +  QTD  K     PL EKL  +D  +  R+++     +   E+R+++FQR +E R   +++ E+ R +D EI +IK N +E   KA +   + +E  Y+++  AL +RER + E  QQ  + QERE Y QRQ IL ++  +++RE ++K+E E  ERE ++ + + K K + +  R  ++K+ E     ++  E+  +KL+++ R +++ + VEV E  L+E+++ +  EK +++++K++L ++ +  NE+                          D+  Y  LK+Q     +++E  + +L +  S+N++++ R   LL++   P+ E  +L  +LER ++  ++E+++  +QK+ LE RL EE+   R L  +  +Q   +  ++R++ + +    ++ R            N  G ++   Q+ G   P  +R  P     SP S   ++R  +    A             T E  H+VD   + +                D  D+   AK++L +LD+E   + KAY +F  R+ N
Sbjct:   16 LRNRLYHTLRNRGLVDSIKSQLRNSLVTELQQNVRGPLTLKDLQT--PEEG-SLLHRASNSLVANHLRACQYEYSLSVFLPECGLSQDKKFETSDLLKLLNISSQSRLYQRLASHTQQDSKKGFLWQLLSEVSSLHANSINTVGCQTDLIKMGPITPLDEKLSDVDEFYSSRREEFLRTGRAGAEERLLSFQRQLEDRYNTQLKMELARMRDAEISTIKMNEKENARKATEQARRELERVYKDKYDALVNRERNASERLQQQTEIQERETYAQRQTILEEIEAVRQREAEVKREAEVNEREKKLTERRVKDKEDDLRRRELEVKQKENSFEQRLQNEMAQFKLDQQARYIERVQNVEVREATLKEQERIVSDEKASLQQVKDQLREKTHRVNELETQISEVRYSEVNANKNNEYLNAKLRDMSDYKTLKEQVILYRNELETVRTRLAEVLSMNERERGRQEELLRELRRPSPESLMLHRDLERCKEELRQEQTLFSQQKQLLEARLKEELDRNRDLVQRFEEQNLQMREMNREVVDLRQSLHMTTRALNNEVYGKQDDNDEGDLNESRQSAGTGTPGRSRGKP-----SPASGHFKQRSSAGVRKAGRNVGPGLRLDFDTKEVYHDVDSDFVSVSQGRDGLFYEDDISSADSADIIAQAKYRLRSLDKEAHNLEKAYHDFHCRVTN 693

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BLAST of OFD1 vs. TrEMBL
Match: A0A1S3JJQ6 (oral-facial-digital syndrome 1 protein homolog OS=Lingula unguis OX=7574 GN=LOC106173529 PE=4 SV=1)

HSP 1 Score: 184.111 bits (466), Expect = 1.003e-43
Identity = 152/553 (27.49%), Postives = 292/553 (52.80%), Query Frame = 3

Query:   12 LYEFLLKFKMSENSCDSDFTY---STKSVKTDLNFQNKLLKLMKEKGVVDKLKTQVRQNLISEIAAKESIFNLKNNSNDKPEKSFD--IFYHSSSSAIYEYLDKNNFHFTKSVFVPESGIKNDKFYTAEELLRVLQLDKNSEFYKKLQSDLL-NTDKSFILCLLKTISEYHTFKQSEIEIQT--DKPEKFIPLSEKLQKLDLQFE----DRQKQGTLKTQQLYEDRIVAFQRDMEKRLRQEMENEIQRFKDHEILSIKRNAEEEFNKALKSKLKIMEEEYQNRLAALKDRERASQENHQQFKDSQERENYFQRQQILRDLSNIQERELQMKKEKEHLEREFEMMKEQHKIKLNQVEERNSKLKELEMGINMKITQEVNSYKLNEEKRLVQKWKEVEVFEMKLQEEKKYLDSEKCTVEKLKEEL-----------------------TKRQYLFNEMDL---ISYPVLKQQNNSLLDQIEEFKXXXXXXXXXXXXDKHRISCLLKQKMG-----PNFEQSVLSNELERARDIFKRERSVLEEQKEALEKRLLEE 1541
            + E+  +F +      S   Y   ++ SV +    ++KL   ++ KGV+D LK+Q+R  L+ E+       +LK      P++  D  +   +++S + ++L + +++++  VF+PESG   DK +T ++LL++L +  +S+ YK L   +  ++ K F+  LL  ++  H     +   QT  D       LS +L K+D +F+    +  K   L T    E+RI++ QR +E+R ++E + E++RFK+ +    K   +E+  K ++   K ME+ Y+ +  AL +RERA+ E  Q+ ++ QE+E Y QRQ +L ++  ++ERE++++K+ E ++RE ++ +++ K     +++R   +  LE   + ++  +V  +K+ E+ RL+++ K +EV E +L +E K L  E+   + ++EEL                       T + Y   +  L   + Y  +K++N  +  ++E  K +  +    N++++ R   LLK  MG     P  E  +L  EL+RA+D  K+E++V E QK+  + R+ EE
Sbjct:   10 IAEYFCRFSLCGTVQGSLLVYNMSTSTSVLSADELKHKLYSSLRGKGVLDSLKSQLRNKLVHELQHSVLGSSLKTKP---PQQQADSSLSLTAANSLVADHLRRCHYNYSLGVFIPESGASQDKVFTTQDLLQLLHISPHSKLYKTLTESMPESSSKGFLWQLLTALAGSHAGLSQDTSTQTSRDGHGAMSILSTRLSKVDEEFDTLLHENSKSHALGT----EERILSIQRHLEERFKEETKLELERFKETQFTKFKLQEKEKARKEIEKARKEMEQTYRAKCDALSERERAATERLQRRQEQQEKELYQQRQSLLEEIDKVREREVEVRKDLEIMKRESQLHEDKMKSWEGVLKKREDSVHRLEEEFDQRLQIDVARFKIEEQGRLLERTKNLEVQEARLSDELKRLGEEREAQQSVREELRINKARVAELEAQIQALHHEKISTSKHYEVAQERLRETVDYRSIKEENAVMKRELETTKMRQAELLHENERERQRYESLLKD-MGERTKQPTPESLLLQRELQRAQDRLKQEQAVFEHQKQQSDARIKEE 554

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BLAST of OFD1 vs. Ensembl Cavefish
Match: ENSAMXT00000030176.1 (pep primary_assembly:Astyanax_mexicanus-2.0:APWO02000109.1:886781:901818:-1 gene:ENSAMXG00000001654.2 transcript:ENSAMXT00000030176.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 114.005 bits (284), Expect = 2.974e-25
Identity = 77/310 (24.84%), Postives = 168/310 (54.19%), Query Frame = 3

Query:  105 FQNKLLKLMKEKGVVDKLKTQVRQNLISEI-AAKESIFNLKNNSNDKPEKSFDIFYHSSSSAIYEYLDKNNFHFTKSVFVPESGIKNDKFYTAEELLRVLQLDKNSEFYKKLQSDLLNTDKSFILCLLKTISEYHT---FKQSEIEIQTDKPEKFIPLSEKLQKLDLQFEDRQKQGTLKTQQLYEDRIVAFQRDMEKRLRQEMENEIQRFKDHEILSIKRNAEEEFNKALKSKLKIMEEEYQNRLAALKDRERASQENHQQFKDSQERENYFQRQQILRDLSNIQERELQMKKEKEHLEREFEMMKEQHK 1022
             + +L +  K KG++D LKTQ+R  LI E+ +  E +    +   D    S  +   +S+S + ++L +  + +T SVF PE G+  DK ++  +LL++L++   S  Y  + S++ +  K  ++ LL  +  +      + ++ +  +  P+    L EKLQ +D ++E  +++G        E ++  F+++ME++ R E++ ++Q F++ E+  ++   +E   + +      +E+ Y+ +  AL  RE+ + E  Q+ ++ +E+E Y QRQ +L+++  ++ RE +++   E  E+  ++ +E+ K
Sbjct:   11 LRKRLYQTFKNKGLLDTLKTQLRNQLIQELQSPGEPVPRGLSAKGD----SVSVL--ASNSLVIDHLHRCGYEYTLSVFYPECGLSKDKVFSTRDLLQLLKISPQSPLYTSVVSNVQSGQKGLLMNLLSELIAHRAHLQLRDADTQTSSTPPDSTQSLVEKLQVVDEEYEVLRQKGNRWAS--VEAKLAEFRKEMEEQARAELKAKLQHFQEVEVSRVRMEEQERSRREVSEIRHRLEKNYELKAEALMSREKNAIERLQKQQEIEEKEVYAQRQALLKEIETVRNREAELRLRTEAFEKTCKLHEEKVK 312

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BLAST of OFD1 vs. Ensembl Cavefish
Match: ENSAMXT00000001699.2 (pep primary_assembly:Astyanax_mexicanus-2.0:APWO02000109.1:886781:901818:-1 gene:ENSAMXG00000001654.2 transcript:ENSAMXT00000001699.2 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 113.62 bits (283), Expect = 3.277e-25
Identity = 77/310 (24.84%), Postives = 168/310 (54.19%), Query Frame = 3

Query:  105 FQNKLLKLMKEKGVVDKLKTQVRQNLISEI-AAKESIFNLKNNSNDKPEKSFDIFYHSSSSAIYEYLDKNNFHFTKSVFVPESGIKNDKFYTAEELLRVLQLDKNSEFYKKLQSDLLNTDKSFILCLLKTISEYHT---FKQSEIEIQTDKPEKFIPLSEKLQKLDLQFEDRQKQGTLKTQQLYEDRIVAFQRDMEKRLRQEMENEIQRFKDHEILSIKRNAEEEFNKALKSKLKIMEEEYQNRLAALKDRERASQENHQQFKDSQERENYFQRQQILRDLSNIQERELQMKKEKEHLEREFEMMKEQHK 1022
             + +L +  K KG++D LKTQ+R  LI E+ +  E +    +   D    S  +   +S+S + ++L +  + +T SVF PE G+  DK ++  +LL++L++   S  Y  + S++ +  K  ++ LL  +  +      + ++ +  +  P+    L EKLQ +D ++E  +++G        E ++  F+++ME++ R E++ ++Q F++ E+  ++   +E   + +      +E+ Y+ +  AL  RE+ + E  Q+ ++ +E+E Y QRQ +L+++  ++ RE +++   E  E+  ++ +E+ K
Sbjct:   14 LRKRLYQTFKNKGLLDTLKTQLRNQLIQELQSPGEPVPRGLSAKGD----SVSVL--ASNSLVIDHLHRCGYEYTLSVFYPECGLSKDKVFSTRDLLQLLKISPQSPLYTSVVSNVQSGQKGLLMNLLSELIAHRAHLQLRDADTQTSSTPPDSTQSLVEKLQVVDEEYEVLRQKGNRWAS--VEAKLAEFRKEMEEQARAELKAKLQHFQEVEVSRVRMEEQERSRREVSEIRHRLEKNYELKAEALMSREKNAIERLQKQQEIEEKEVYAQRQALLKEIETVRNREAELRLRTEAFEKTCKLHEEKVK 315

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BLAST of OFD1 vs. Ensembl Nematostella
Match: EDO40814 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S671])

HSP 1 Score: 70.0922 bits (170), Expect = 2.737e-14
Identity = 36/118 (30.51%), Postives = 68/118 (57.63%), Query Frame = 3

Query:  114 KLLKLMKEKGVVDKLKTQVRQNLISEI--AAKESIFNLKNNSNDKPEKSFDIFYHSSSSAIYEYLDKNNFHFTKSVFVPESGIKNDKFYTAEELLRVLQLDKNSEFYKKLQSDLLNTD 461
            KL    + +GV+D LK+Q+R  L+ E+   A  +I + K  + D+      ++Y +++S +  +L+  NF +T SVF+PE G   DK +++ ++  +L+++  S  Y  L S L+ T+
Sbjct:   14 KLFYTFRNRGVIDSLKSQLRNRLVLELQQTANINIASGKKKTTDQTS----LYYQAANSLVANHLENCNFEYTLSVFLPECGTSKDKLFSSHDICHLLKIEPGSPLYNSLVSTLMITN 127

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BLAST of OFD1 vs. Ensembl Medaka
Match: ofd1 (OFD1 centriole and centriolar satellite protein [Source:NCBI gene;Acc:101169988])

HSP 1 Score: 114.005 bits (284), Expect = 2.574e-25
Identity = 126/541 (23.29%), Postives = 266/541 (49.17%), Query Frame = 3

Query:  105 FQNKLLKLMKEKGVVDKLKTQVRQNLISEI-----AAKESIFNLKNNSNDKPEKSFDIFYHSSSSAIYEYLDKNNFHFTKSVFVPESGIKNDKFYTAEELLRVLQLDKNSEFYKKLQSDLLNTDKSFILCLLKTISEYHT-FKQSEIEIQTDKPEKFI-PLSEKLQKLDLQFEDRQKQGTLKTQQLYEDRIVAFQRDMEKRLRQEMENEIQRFKDHEILSIKRNAEEEFNKALKSKLKIMEEEYQNRLAALKDRERASQENHQQFKDSQERENYFQRQQILRDLSNIQERELQMKKEKEHLEREFEMMKEQHKIKLNQVEERNSKLKELEMGINMKITQEVNSYKLNEEKRLVQKWKEV-------EVFEMKLQEEKKYLD------SEKCT-VEKLKEELTKRQ----YLFNEMDLI--------SYPVLKQQNNSLLDQIEEFKXXXXXXXXXXXXDKHRISCLLKQKMGPNFEQSVLSNELERARDIFKRERSVLEEQKEALEKRLLEEIKSKRILTDQLSQQQDLVEMLSRQISENK 1628
             + +L +  K KG +D LK Q+R  LI E+       +E +  L       P K+  +   + +S + ++L  + + +T SVF PESG+  DK    ++LL++L+++  S+ YK +     N +K F+  LL  ++ ++    + + + QT     +   L EK++ +D ++E   K         ++ ++ A++R++E ++   M  ++  FK+ E+  ++   + +F+K   +  + +E  Y+ +  AL +RE+ + E  Q+ K+ +E++ Y QRQ  L+D+ +++ RE +++   E  E+  ++  E+ K     +  R   +K +E     K+  E++SY+L  ++  +++ +++        V   ++Q+E   L+      S  C  +++L+ +L   Q     L  + DL+         YP L+++   L +Q++  K+QL++    N++       L  +   P+ EQ  L  EL+R ++  + +    + Q+E L+ +L  E      L  QL   Q+  + ++  + E K
Sbjct:   15 LRKRLYQTFKSKGFLDSLKAQLRNQLIQELKHPPLTGQEPVPRLV------PLKTDTLLASACNSIVADHLQASGYEYTLSVFCPESGLNKDKVLKKDDLLQILKINPESKLYKSVACKE-NDNKGFLFNLLTHLTSHNAPSPRQDADAQTTTASNYGESLVEKMKTIDKEYEHFNKDQMFS----FQSKLAAYKREIETQMEASMNVKLHHFKEVEMAKVRLEEKSKFHKEFDNLKRELERNYEMKAKALMEREKNAIEGLQKHKEIEEKDMYMQRQSTLKDIESLRYRENELRMRMEAFEKTCQIHAEKVKTAEELLRRRELAVKTMEDTYEQKLKNELSSYQLELKEEFIKRTEKLTENENRNRVEAARIQQESAALNARSEEHSRTCAKLKQLQADLDTAQQQISLLTQQKDLLRERLESTSDYPSLRRERTELQEQMQLLKKQLEEVREENRR-------LHAEMATPSKEQLALQVELQRLQNARRLDEEDFDNQREVLQAQLQNESDRCAQLKAQLLDHQERAQWMNSHVEELK 537

[Close]

BLAST of OFD1 vs. Ensembl Medaka
Match: ofd1 (OFD1 centriole and centriolar satellite protein [Source:NCBI gene;Acc:101169988])

HSP 1 Score: 112.849 bits (281), Expect = 5.048e-25
Identity = 126/541 (23.29%), Postives = 266/541 (49.17%), Query Frame = 3

Query:  105 FQNKLLKLMKEKGVVDKLKTQVRQNLISEI-----AAKESIFNLKNNSNDKPEKSFDIFYHSSSSAIYEYLDKNNFHFTKSVFVPESGIKNDKFYTAEELLRVLQLDKNSEFYKKLQSDLLNTDKSFILCLLKTISEYHT-FKQSEIEIQTDKPEKFI-PLSEKLQKLDLQFEDRQKQGTLKTQQLYEDRIVAFQRDMEKRLRQEMENEIQRFKDHEILSIKRNAEEEFNKALKSKLKIMEEEYQNRLAALKDRERASQENHQQFKDSQERENYFQRQQILRDLSNIQERELQMKKEKEHLEREFEMMKEQHKIKLNQVEERNSKLKELEMGINMKITQEVNSYKLNEEKRLVQKWKEV-------EVFEMKLQEEKKYLD------SEKCT-VEKLKEELTKRQ----YLFNEMDLI--------SYPVLKQQNNSLLDQIEEFKXXXXXXXXXXXXDKHRISCLLKQKMGPNFEQSVLSNELERARDIFKRERSVLEEQKEALEKRLLEEIKSKRILTDQLSQQQDLVEMLSRQISENK 1628
             + +L +  K KG +D LK Q+R  LI E+       +E +  L       P K+  +   + +S + ++L  + + +T SVF PESG+  DK    ++LL++L+++  S+ YK +     N +K F+  LL  ++ ++    + + + QT     +   L EK++ +D ++E   K         ++ ++ A++R++E ++   M  ++  FK+ E+  ++   + +F+K   +  + +E  Y+ +  AL +RE+ + E  Q+ K+ +E++ Y QRQ  L+D+ +++ RE +++   E  E+  ++  E+ K     +  R   +K +E     K+  E++SY+L  ++  +++ +++        V   ++Q+E   L+      S  C  +++L+ +L   Q     L  + DL+         YP L+++   L +Q++  K+QL++    N++       L  +   P+ EQ  L  EL+R ++  + +    + Q+E L+ +L  E      L  QL   Q+  + ++  + E K
Sbjct:   15 LRKRLYQTFKSKGFLDSLKAQLRNQLIQELKHPPLTGQEPVPRLV------PLKTDTLLASACNSIVADHLQASGYEYTLSVFCPESGLNKDKVLKKDDLLQILKINPESKLYKSVACKE-NDNKGFLFNLLTHLTSHNAPSPRQDADAQTTTASNYGESLVEKMKTIDKEYEHFNKDQMFS----FQSKLAAYKREIETQMEASMNVKLHHFKEVEMAKVRLEEKSKFHKEFDNLKRELERNYEMKAKALMEREKNAIEGLQKHKEIEEKDMYMQRQSTLKDIESLRYRENELRMRMEAFEKTCQIHAEKVKTAEELLRRRELAVKTMEDTYEQKLKNELSSYQLELKEEFIKRTEKLTENENRNRVEAARIQQESAALNARSEEHSRTCAKLKQLQADLDTAQQQISLLTQQKDLLRERLESTSDYPSLRRERTELQEQMQLLKKQLEEVREENRR-------LHAEMATPSKEQLALQVELQRLQNARRLDEEDFDNQREVLQAQLQNESDRCAQLKAQLLDHQERAQWMNSHVEELK 537

[Close]

BLAST of OFD1 vs. Ensembl Medaka
Match: ofd1 (OFD1 centriole and centriolar satellite protein [Source:NCBI gene;Acc:101169988])

HSP 1 Score: 90.5077 bits (223), Expect = 4.564e-18
Identity = 126/580 (21.72%), Postives = 266/580 (45.86%), Query Frame = 3

Query:  105 FQNKLLKLMKEKGVVDKLKTQVRQNLISEI-----AAKESIFNLKNNSNDKPEKSFDIFYHSSSSAIYEYLDKNNFHFTKSVFVPESGIKNDKFYTAEELLRVLQLDKNSEFYKKLQSDLLNTDKSFILCLLKTISEYHT-FKQSEIEIQTDKPEKFI-PLSEKLQKLDLQFEDRQKQGTLKTQQLYEDRIVAFQRDMEKRLRQEMENEI---------------------------------------QRFKDHEILSIKRNAEEEFNKALKSKLKIMEEEYQNRLAALKDRERASQENHQQFKDSQERENYFQRQQILRDLSNIQERELQMKKEKEHLEREFEMMKEQHKIKLNQVEERNSKLKELEMGINMKITQEVNSYKLNEEKRLVQKWKEV-------EVFEMKLQEEKKYLD------SEKCT-VEKLKEELTKRQ----YLFNEMDLI--------SYPVLKQQNNSLLDQIEEFKXXXXXXXXXXXXDKHRISCLLKQKMGPNFEQSVLSNELERARDIFKRERSVLEEQKEALEKRLLEEIKSKRILTDQLSQQQDLVEMLSRQISENK 1628
             + +L +  K KG +D LK Q+R  LI E+       +E +  L       P K+  +   + +S + ++L  + + +T SVF PESG+  DK    ++LL++L+++  S+ YK +     N +K F+  LL  ++ ++    + + + QT     +   L EK++ +D ++E   K         ++ ++ A++R++E ++   M  ++                                         FK+ E+  ++   + +F+K   +  + +E  Y+ +  AL +RE+ + E  Q+ K+ +E++ Y QRQ  L+D+ +++ RE +++   E  E+  ++  E+ K     +  R   +K +E     K+  E++SY+L  ++  +++ +++        V   ++Q+E   L+      S  C  +++L+ +L   Q     L  + DL+         YP L+++   L +Q++  K+QL++    N++       L  +   P+ EQ  L  EL+R ++  + +    + Q+E L+ +L  E      L  QL   Q+  + ++  + E K
Sbjct:   15 LRKRLYQTFKSKGFLDSLKAQLRNQLIQELKHPPLTGQEPVPRLV------PLKTDTLLASACNSIVADHLQASGYEYTLSVFCPESGLNKDKVLKKDDLLQILKINPESKLYKSVACKE-NDNKGFLFNLLTHLTSHNAPSPRQDADAQTTTASNYGESLVEKMKTIDKEYEHFNKDQMFS----FQSKLAAYKREIETQMEASMNVKVFILTHAYMHAGLCTQSIVSDFIFVAPPIPELYVFFFFKLHHFKEVEMAKVRLEEKSKFHKEFDNLKRELERNYEMKAKALMEREKNAIEGLQKHKEIEEKDMYMQRQSTLKDIESLRYRENELRMRMEAFEKTCQIHAEKVKTAEELLRRRELAVKTMEDTYEQKLKNELSSYQLELKEEFIKRTEKLTENENRNRVEAARIQQESAALNARSEEHSRTCAKLKQLQADLDTAQQQISLLTQQKDLLRERLESTSDYPSLRRERTELQEQMQLLKKQLEEVREENRR-------LHAEMATPSKEQLALQVELQRLQNARRLDEEDFDNQREVLQAQLQNESDRCAQLKAQLLDHQERAQWMNSHVEELK 576

[Close]

BLAST of OFD1 vs. Planmine SMEST
Match: SMESG000046592.1 (SMESG000046592.1)

HSP 1 Score: 1649.03 bits (4269), Expect = 0.000e+0
Identity = 888/896 (99.11%), Postives = 891/896 (99.44%), Query Frame = 3

Query:   39 MSENSCDSDFTYSTKSVKTDLNFQNKLLKLMKEKGVVDKLKTQVRQNLISEIAAKESIFNLKNNSNDKPEKSFDIFYHSSSSAIYEYLDKNNFHFTKSVFVPESGIKNDKFYTAEELLRVLQLDKNSEFYKKLQSDLLNTDKSFILCLLKTISEYHTFKQSEIEIQTDKPEKFIPLSEKLQKLDLQFEDRQKQGTLKTQQLYEDRIVAFQRDMEKRLRQEMENEIQRFKDHEILSIKRNAEEEFNKALKSKLKIMEEEYQNRLAALKDRERASQENHQQFKDSQERENYFQRQQILRDLSNIQERELQMKKEKEHLEREFEMMKEQHKIKLNQVEERNSKLKELEMGINMKITQEVNSYKLNEEKRLVQKWKEVEVFEMKLQEEKKYLDSEKCTVEKLKEELTKRQYLFNEMDLISYPVLKQQNNSLLDQIEEFKXXXXXXXXXXXXDKHRISCLLKQKMGPNFEQSVLSNELERARDIFKRERSVLEEQKEALEKRLLEEIKSKRILTDQLSQQQDLVEMLSRQISENKDLSYRNKCGFISSRSQNYGPYSNRNPPTNRDSSPHSPTDRRRRLSNFESATNEFLHEVDEYNLPMDVEDLTTDAKHKLMNLDEETEQINKAYFEFKNRMANSFSKIGEFHVELHPELVSKSFKNGIEEGRRLKKTKSNELPIFFDSNSRTASFPMDNEELLPKILETDISNNHEMNIAKTNYYEREITMRNDENYETESDNPVEVSHIPNIYNYTNETNNVNPDVPNIVENDNKSVSNLDSEPNPDSDVINLDQDWRNTNYDAKNQKFVVSNERDKVDNSATKMRXXXXXXXXXXXIDPVXXXXXXXXXXXXXTEMFPGNTDNPGINPAKVPRXXXXXXXXXXXXXXXXXXXXXXXXXXPIQSESE 2726
            MSENS DSDFTYSTKSVKTDLNFQNKLLKLMKEKGVVDKLKTQVRQNLISEIAAKESIFNLKNNSNDKPEKSFDIFYHSSSSAIYEYLDKNNFHFTKSVFVPESGIKNDKFYTAEELLRVLQLDKNSEFYKKLQSDLLNTDKSFILCLLKTISEYHTFKQSEIEIQTDKPEKFIPLSEKLQKLDLQFEDRQKQGTLKTQQLYEDRIVAFQRDMEKRLRQEMENEIQRFKDHEILSIKRNAEEEFNKALKSKLKIMEEEYQNRLAALKDRERASQENHQQFKDSQERENYFQRQQILRDLSNIQERELQMKKEKEHLEREFEMMKEQHKIKLNQVEERNSKLKELEMGINMKITQEVNSYKLNEEKRLVQKWKEVEVFEMKLQEEKKYLDSEKCTVEKLKEELTKRQYLFNEMDLISYPVLKQQNNSLLDQIEEFKQQLQQQNSINQQDKHRISCLLKQKMGPNFEQSVLSNELERARDIFKRERSVLEEQKEALEKRLLEEIKSKRILTDQLSQQ DLVEMLSRQISENKDLSYRNKCGFISSRSQNYGPYSNRNPPTNRDSSPHSPTDRRRRLSNFESATNEFLHEVDEYNLPMDVEDLTTDAKHKLMNLDEETEQINKAYFEFKNR+ANSFSKIGEFHVELHPELVSKSFKNGIEEGRRLK TKSNELPIFFDSNSRT SFPMDNEELLPKILETDIS+NHEMNIAKTNYYEREITMRNDENYETESDNPVEVS IPNIYNYTNETNNVNPDVPNIVENDNKSVSNLDSEPNPDSDVINLDQDWRNTNYDAKNQKFVVSNERDKVDNSATKMRNEG+DDGENDEIDPVMKKYMELLKKKKETEMFPGNTDNPGINPAKVPRISESEQESEIIKSISENSNMSNKKESPIQSESE
Sbjct:    1 MSENSYDSDFTYSTKSVKTDLNFQNKLLKLMKEKGVVDKLKTQVRQNLISEIAAKESIFNLKNNSNDKPEKSFDIFYHSSSSAIYEYLDKNNFHFTKSVFVPESGIKNDKFYTAEELLRVLQLDKNSEFYKKLQSDLLNTDKSFILCLLKTISEYHTFKQSEIEIQTDKPEKFIPLSEKLQKLDLQFEDRQKQGTLKTQQLYEDRIVAFQRDMEKRLRQEMENEIQRFKDHEILSIKRNAEEEFNKALKSKLKIMEEEYQNRLAALKDRERASQENHQQFKDSQERENYFQRQQILRDLSNIQERELQMKKEKEHLEREFEMMKEQHKIKLNQVEERNSKLKELEMGINMKITQEVNSYKLNEEKRLVQKWKEVEVFEMKLQEEKKYLDSEKCTVEKLKEELTKRQYLFNEMDLISYPVLKQQNNSLLDQIEEFKQQLQQQNSINQQDKHRISCLLKQKMGPNFEQSVLSNELERARDIFKRERSVLEEQKEALEKRLLEEIKSKRILTDQLSQQHDLVEMLSRQISENKDLSYRNKCGFISSRSQNYGPYSNRNPPTNRDSSPHSPTDRRRRLSNFESATNEFLHEVDEYNLPMDVEDLTTDAKHKLMNLDEETEQINKAYFEFKNRIANSFSKIGEFHVELHPELVSKSFKNGIEEGRRLKNTKSNELPIFFDSNSRTGSFPMDNEELLPKILETDISDNHEMNIAKTNYYEREITMRNDENYETESDNPVEVSPIPNIYNYTNETNNVNPDVPNIVENDNKSVSNLDSEPNPDSDVINLDQDWRNTNYDAKNQKFVVSNERDKVDNSATKMRNEGEDDGENDEIDPVMKKYMELLKKKKETEMFPGNTDNPGINPAKVPRISESEQESEIIKSISENSNMSNKKESPIQSESE 896

The following BLAST results are available for this feature:

BLAST of OFD1 vs. Ensembl Human
BLAST of OFD1 vs. Ensembl Celegans
BLAST of OFD1 vs. Ensembl Fly
BLAST of OFD1 vs. Ensembl Zebrafish
BLAST of OFD1 vs. Ensembl Xenopus
BLAST of OFD1 vs. Ensembl Mouse
BLAST of OFD1 vs. UniProt/SwissProt
BLAST of OFD1 vs. TrEMBL
BLAST of OFD1 vs. Ensembl Cavefish
BLAST of OFD1 vs. Ensembl Sea Lamprey
BLAST of OFD1 vs. Ensembl Yeast
BLAST of OFD1 vs. Ensembl Nematostella
BLAST of OFD1 vs. Ensembl Medaka
BLAST of OFD1 vs. Planmine SMEST

BLAST of OFD1 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 4


Match Name	E-value	Identity	Description
OFD1	3.772e-32	26.61	OFD1 centriole and centriolar satellite protein [S...	[more]
OFD1	5.345e-31	27.95	OFD1 centriole and centriolar satellite protein [S...	[more]
OFD1	8.618e-14	26.17	OFD1 centriole and centriolar satellite protein [S...	[more]
OFD1	2.534e-12	32.74	OFD1 centriole and centriolar satellite protein [S...	[more]

BLAST of OFD1 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 0


Match Name	E-value	Identity	Description

BLAST of OFD1 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 0


Match Name	E-value	Identity	Description

BLAST of OFD1 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 1


Match Name	E-value	Identity	Description
ofd1	1.602e-25	24.27	OFD1 centriole and centriolar satellite protein [S...	[more]

BLAST of OFD1 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 2


Match Name	E-value	Identity	Description
OFD1	4.123e-23	24.36	OFD1 centriole and centriolar satellite protein [S...	[more]
OFD1	2.956e-13	23.65	OFD1 centriole and centriolar satellite protein [S...	[more]

BLAST of OFD1 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 1


Match Name	E-value	Identity	Description
Ofd1	6.902e-31	24.81	OFD1, centriole and centriolar satellite protein [...	[more]

BLAST of OFD1 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 3


Match Name	E-value	Identity	Description
sp\|O75665\|OFD1_HUMAN	1.811e-31	26.61	Oral-facial-digital syndrome 1 protein OS=Homo sap...	[more]
sp\|Q80Z25\|OFD1_MOUSE	5.161e-30	24.81	Oral-facial-digital syndrome 1 protein homolog OS=...	[more]
sp\|Q7SZK7\|OFD1_DANRE	8.058e-25	24.08	Oral-facial-digital syndrome 1 protein homolog OS=...	[more]

BLAST of OFD1 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5


Match Name	E-value	Identity	Description
H6WA38	5.800e-128	97.97	OFD1 (Fragment) OS=Schmidtea mediterranea OX=79327...	[more]
A0A2C9KXQ8	1.704e-51	26.49	LisH domain-containing protein OS=Biomphalaria gla...	[more]
A0A2C9KXP3	2.401e-51	26.49	LisH domain-containing protein OS=Biomphalaria gla...	[more]
A0A3S1C016	4.857e-51	26.09	LisH domain-containing protein OS=Elysia chlorotic...	[more]
A0A1S3JJQ6	1.003e-43	27.49	oral-facial-digital syndrome 1 protein homolog OS=...	[more]

BLAST of OFD1 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 2


Match Name	E-value	Identity	Description
ENSAMXT00000030176.1	2.974e-25	24.84	pep primary_assembly:Astyanax_mexicanus-2.0:APWO02...	[more]
ENSAMXT00000001699.2	3.277e-25	24.84	pep primary_assembly:Astyanax_mexicanus-2.0:APWO02...	[more]

BLAST of OFD1 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 0


Match Name	E-value	Identity	Description

BLAST of OFD1 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0


Match Name	E-value	Identity	Description

BLAST of OFD1 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 1


Match Name	E-value	Identity	Description
EDO40814	2.737e-14	30.51	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]

BLAST of OFD1 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 3


Match Name	E-value	Identity	Description
ofd1	2.574e-25	23.29	OFD1 centriole and centriolar satellite protein [S...	[more]
ofd1	5.048e-25	23.29	OFD1 centriole and centriolar satellite protein [S...	[more]
ofd1	4.564e-18	21.72	OFD1 centriole and centriolar satellite protein [S...	[more]

BLAST of OFD1 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 1


Match Name	E-value	Identity	Description
SMESG000046592.1	0.000e+0	99.11	SMESG000046592.1	[more]

Analyses

This transcript is derived from or has results from the following analyses


Analysis Name	Date Performed
Embryonic Stages	2016-07-25
Schmidtea mediterranea smed_20140614 BLASTX Human e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL	2020-05-01
Schmidtea mediterranea Sexual smed_20140614 transcriptome	2016-07-25
Schmidtea mediteranean smed_20140614 Interproscan	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST	2020-05-08

Cross References

External references for this transcript


Database	Accession
SmedGD GBrowse	SMED30013865
GenBank	AFB74720.1

Sequences

The following sequences are available for this feature:

transcript sequence
protein sequence

transcript sequence

>SMED30013865 ID=SMED30013865|Name=OFD1|organism=Schmidtea mediterranea sexual|type=transcript|length=2784bp
CTATATAAATCTTATATGAATTTCTATTAAAATTTAAAATGAGTGAAAAT
TCCTGTGACAGCGATTTTACTTATTCAACTAAATCAGTAAAAACGGATTT
AAATTTTCAAAATAAACTTTTGAAGTTGATGAAAGAAAAAGGTGTTGTTG
ATAAATTGAAAACACAAGTTAGACAAAATCTCATATCGGAAATAGCGGCA
AAAGAATCCATTTTCAATTTAAAGAATAATTCCAACGATAAACCAGAAAA
GTCTTTTGATATATTTTACCATTCTTCGTCCAGTGCGATTTATGAATATT
TAGATAAAAATAATTTTCATTTCACTAAAAGTGTCTTTGTACCAGAGTCT
GGAATAAAAAATGATAAGTTTTATACTGCCGAAGAATTATTGCGGGTTTT
GCAATTGGACAAAAATTCGGAATTTTACAAAAAATTGCAATCCGATTTAT
TAAATACAGACAAGAGTTTTATTTTATGTTTATTGAAAACGATTTCTGAG
TATCATACTTTCAAGCAAAGTGAAATTGAAATACAAACCGACAAGCCGGA
AAAGTTTATCCCATTAAGTGAGAAATTGCAAAAACTCGATTTACAATTCG
AAGATCGACAAAAACAAGGAACTCTTAAAACTCAACAACTTTATGAAGAT
CGAATTGTTGCTTTTCAACGGGACATGGAAAAAAGATTACGCCAAGAAAT
GGAAAATGAGATTCAAAGATTCAAGGATCACGAAATATTATCCATTAAAC
GAAATGCCGAAGAAGAATTCAATAAAGCTCTTAAAAGCAAATTGAAGATT
ATGGAAGAAGAATATCAAAATAGGCTGGCCGCTCTCAAAGACAGAGAACG
AGCATCTCAAGAAAACCATCAGCAATTTAAAGACAGTCAAGAAAGAGAGA
ATTATTTTCAAAGACAGCAAATATTGAGAGATTTATCAAATATACAAGAA
CGTGAATTGCAGATGAAAAAGGAAAAAGAACATTTGGAACGTGAATTTGA
AATGATGAAAGAACAGCACAAAATAAAATTGAATCAAGTAGAGGAGAGAA
ATTCTAAACTGAAAGAATTGGAAATGGGAATTAATATGAAAATCACTCAA
GAAGTCAACAGCTATAAACTCAATGAAGAAAAGCGCTTAGTTCAAAAATG
GAAGGAAGTCGAAGTTTTCGAAATGAAACTTCAAGAAGAAAAAAAGTATC
TGGATTCTGAAAAGTGCACAGTGGAAAAATTAAAAGAAGAATTAACAAAA
AGACAATACTTATTCAATGAAATGGACCTAATTTCTTACCCAGTTCTGAA
ACAGCAAAATAATTCATTGCTCGATCAAATAGAAGAATTTAAACAGCAAC
TTCAACAACAAAATAGTATCAATCAACAAGACAAACACAGAATATCATGT
TTGTTAAAACAAAAAATGGGTCCAAATTTTGAACAATCAGTTCTTTCAAA
TGAATTAGAGCGTGCTAGAGATATTTTCAAAAGAGAACGATCTGTACTTG
AAGAACAGAAAGAAGCACTTGAGAAAAGATTGTTAGAAGAGATAAAAAGC
AAACGTATTCTAACAGATCAGCTCTCTCAGCAGCAAGATCTAGTTGAAAT
GTTATCACGTCAAATTTCAGAGAACAAAGATCTATCTTACAGAAACAAAT
GCGGCTTCATTTCTAGCCGAAGTCAAAACTATGGTCCATACTCCAATCGT
AATCCTCCTACAAACCGAGACTCATCTCCACATTCTCCTACTGACCGTCG
TAGAAGGCTGTCAAATTTTGAGTCAGCAACAAACGAATTCCTTCATGAAG
TTGATGAATACAACCTTCCAATGGATGTTGAAGATTTAACAACCGATGCC
AAGCATAAGCTTATGAATCTAGATGAAGAAACTGAGCAAATTAATAAAGC
TTATTTTGAATTCAAGAATCGAATGGCCAATTCGTTTTCTAAAATCGGAG
AATTTCATGTCGAATTGCATCCGGAATTAGTTTCCAAATCTTTCAAAAAT
GGTATAGAGGAAGGCCGCAGATTGAAAAAAACAAAATCTAATGAACTGCC
AATTTTCTTTGATTCTAACTCTCGTACGGCCTCGTTTCCCATGGATAATG
AAGAACTTTTACCAAAAATTCTAGAAACTGATATTTCAAATAATCATGAA
ATGAATATAGCTAAGACAAATTATTATGAAAGAGAAATTACTATGAGAAA
TGATGAAAACTATGAAACGGAATCTGATAATCCTGTTGAAGTGTCCCATA
TTCCGAATATTTATAATTATACCAATGAAACAAATAATGTAAATCCTGAT
GTACCCAATATCGTAGAAAATGATAATAAATCAGTTTCAAATCTTGATTC
TGAACCAAATCCTGATTCTGACGTAATCAATTTAGATCAAGATTGGCGCA
ATACTAATTATGACGCAAAAAATCAAAAATTTGTGGTATCAAACGAACGT
GACAAAGTCGACAATTCAGCAACTAAGATGAGAAATGAAGGTGATGATGA
TGGGGAAAATGATGAAATTGATCCAGTTATGAAGAAATATATGGAATTAT
TAAAGAAGAAAAAGGAAACTGAAATGTTTCCTGGAAACACGGATAATCCT
GGCATTAATCCTGCAAAAGTTCCTCGAATATCTGAAAGTGAACAAGAATC
AGAAATAATTAAATCTATATCTGAAAATTCAAACATGTCAAATAAAAAGG
AAAGTCCAATACAAAGTGAATCAGAATCTTTTTGGTGAATTAAAAGCAAA
TTGTTGATAATTTTTTAATTATGTAATAAATGAG

protein sequence of SMED30013865-orf-1

>SMED30013865-orf-1 ID=SMED30013865-orf-1|Name=SMED30013865-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=900bp
MSENSCDSDFTYSTKSVKTDLNFQNKLLKLMKEKGVVDKLKTQVRQNLIS
EIAAKESIFNLKNNSNDKPEKSFDIFYHSSSSAIYEYLDKNNFHFTKSVF
VPESGIKNDKFYTAEELLRVLQLDKNSEFYKKLQSDLLNTDKSFILCLLK
TISEYHTFKQSEIEIQTDKPEKFIPLSEKLQKLDLQFEDRQKQGTLKTQQ
LYEDRIVAFQRDMEKRLRQEMENEIQRFKDHEILSIKRNAEEEFNKALKS
KLKIMEEEYQNRLAALKDRERASQENHQQFKDSQERENYFQRQQILRDLS
NIQERELQMKKEKEHLEREFEMMKEQHKIKLNQVEERNSKLKELEMGINM
KITQEVNSYKLNEEKRLVQKWKEVEVFEMKLQEEKKYLDSEKCTVEKLKE
ELTKRQYLFNEMDLISYPVLKQQNNSLLDQIEEFKQQLQQQNSINQQDKH
RISCLLKQKMGPNFEQSVLSNELERARDIFKRERSVLEEQKEALEKRLLE
EIKSKRILTDQLSQQQDLVEMLSRQISENKDLSYRNKCGFISSRSQNYGP
YSNRNPPTNRDSSPHSPTDRRRRLSNFESATNEFLHEVDEYNLPMDVEDL
TTDAKHKLMNLDEETEQINKAYFEFKNRMANSFSKIGEFHVELHPELVSK
SFKNGIEEGRRLKKTKSNELPIFFDSNSRTASFPMDNEELLPKILETDIS
NNHEMNIAKTNYYEREITMRNDENYETESDNPVEVSHIPNIYNYTNETNN
VNPDVPNIVENDNKSVSNLDSEPNPDSDVINLDQDWRNTNYDAKNQKFVV
SNERDKVDNSATKMRNEGDDDGENDEIDPVMKKYMELLKKKKETEMFPGN
TDNPGINPAKVPRISESEQESEIIKSISENSNMSNKKESPIQSESESFW*

Annotated Terms

The following terms have been associated with this transcript:

Vocabulary: **Planarian Anatomy**
Term	Definition
PLANA:0000016	pharynx
PLANA:0000034	epidermis
PLANA:0000099	neuron
PLANA:0000418	head
PLANA:0002032	epidermal cell

Vocabulary: **INTERPRO**
Term	Definition
IPR006594	LisH

Vocabulary: **molecular function**
Term	Definition
GO:0005515	protein binding
GO:0042802	identical protein binding
GO:0043014	alpha-tubulin binding
GO:0043015	gamma-tubulin binding

Vocabulary: **biological process**
Term	Definition
GO:0000086	G2/M transition of mitotic cell cycle
GO:0030030	cell projection organization
GO:0060271	cilium morphogenesis
GO:0060287	epithelial cilium movement involved in determination of left/right asymmetry
GO:0097711	ciliary basal body docking

Vocabulary: **cellular component**
Term	Definition
GO:0005634	nucleus
GO:0005737	cytoplasm
GO:0005813	centrosome
GO:0005814	centriole
GO:0005815	microtubule organizing center
GO:0005829	cytosol
GO:0005856	cytoskeleton
GO:0005929	cilium
GO:0016020	membrane
GO:0034451	centriolar satellite
GO:0036064	ciliary basal body
GO:0042995	cell projection

InterPro

Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01


IPR Term	IPR Description	Source	Source Term	Source Description	Alignment
None	No IPR available	COILS	Coil	Coil	coord: 218..238
None	No IPR available	COILS	Coil	Coil	coord: 306..351
None	No IPR available	COILS	Coil	Coil	coord: 424..451
None	No IPR available	COILS	Coil	Coil	coord: 245..283
None	No IPR available	COILS	Coil	Coil	coord: 477..511
None	No IPR available	COILS	Coil	Coil	coord: 388..408
None	No IPR available	MOBIDB_LITE	mobidb-lite	disorder_prediction	coord: 552..578
None	No IPR available	MOBIDB_LITE	mobidb-lite	disorder_prediction	coord: 808..834
None	No IPR available	MOBIDB_LITE	mobidb-lite	disorder_prediction	coord: 552..570
None	No IPR available	MOBIDB_LITE	mobidb-lite	disorder_prediction	coord: 881..906
None	No IPR available	MOBIDB_LITE	mobidb-lite	disorder_prediction	coord: 849..906
None	No IPR available	PANTHER	PTHR15431	FGFR1 ONCOGENE PARTNER/LISH DOMAIN-CONTAINING PROTEIN	coord: 29..641
None	No IPR available	PANTHER	PTHR15431:SF14	ORAL-FACIAL-DIGITAL SYNDROME 1 PROTEIN	coord: 29..641
IPR006594	LIS1 homology motif	PFAM	PF16045	LisH_2	coord: 89..113 e-value: 1.8E-8 score: 33.2
IPR006594	LIS1 homology motif	PROSITE	PS50896	LISH	coord: 83..115 score: 7.913

Main menu

OFD1

Zeng et. al., 2018

▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Overview

Single cell RNA-seq of pluripotent neoblasts and its early progenies

Explore this single cell expression dataset with our NB Cluster Shiny App

Neoblast Population

Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Davies et. al., 2017

PAGE et. al., 2020

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE

PAGE Curations: 8

Owlery

blazegraph-runner