Rac-1

Overview
NameRac-1 (ADW66119.1)
Smed IDSMED30013863
Length (bp)1606
Neoblast Clusters

Zeng et. al., 2018




▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 



 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)




Explore this single cell expression dataset with our NB Cluster Shiny App




 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of Rac-1 (SMED30013863) t-SNE clustered cells

Violin plots show distribution of expression levels for Rac-1 (SMED30013863) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of Rac-1 (SMED30013863) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for Rac-1 (SMED30013863) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017




Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020




SMED30013863

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 8

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
gutSMED30013863h1SMcG0005547 Contig5482GPL15192PMID:23079596
Forsthoefel et al., 2012
whole organism asexual adult colorimetric in situ hybridization evidence
intestinal phagocyteSMED30013863h1SMcG0005547 Contig5482GPL15192PMID:23079596
Forsthoefel et al., 2012
FACS sorted cell population asexual adult cDNA to DNA expression microarray evidence
central nervous systemSMED30013863h1SMcG0005547 Contig5482GPL15192PMID:23079596
Forsthoefel et al., 2012
whole organism asexual adult colorimetric in situ hybridization evidence
protonephridiaSMED30013863h1SMcG0005547 dd_Smed_v4_610_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
gutSMED30013863h1SMcG0005547 dd_Smed_v4_610_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
cephalic gangliaSMED30013863h1SMcG0005547 dd_Smed_v4_610_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
parenchymal cellSMED30013863h1SMcG0005547 dd_Smed_v4_610_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
neoblastSMED30013863h1SMcG0005547 GU591872smed_ncbi_20240424PMID:21356107
Fernández-Taboada et al., 2011
whole organism asexual adult colorimetric in situ hybridization evidence
Note: Hover over icons to view figure legend
Homology
BLAST of Rac-1 vs. Ensembl Human
Match: RAC1 (Rac family small GTPase 1 [Source:HGNC Symbol;Acc:HGNC:9801])

HSP 1 Score: 332.413 bits (851), Expect = 4.674e-112
Identity = 158/192 (82.29%), Postives = 173/192 (90.10%), Query Frame = 2
Query:  164 MQGIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDNKPVNLGLWDTAGQEDYDRLRPLSYPQTDVFLICFSLINSSSYENVRAKWYPEITHHCPNTPIILVGTKLDLRENHMNGEAGKDRRNTPISYPQGLVLAKEIGAVKYLECSALTQKGLKSVFDEAIRAVLCPKP--PRKKTCKFL 733
            MQ IKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVD KPVNLGLWDTAGQEDYDRLRPLSYPQTDVFLICFSL++ +S+ENVRAKWYPE+ HHCPNTPIILVGTKLDLR++    E  K+++ TPI+YPQGL +AKEIGAVKYLECSALTQ+GLK+VFDEAIRAVLCP P   RK+ C  L
Sbjct:    1 MQAIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDGKPVNLGLWDTAGQEDYDRLRPLSYPQTDVFLICFSLVSPASFENVRAKWYPEVRHHCPNTPIILVGTKLDLRDDKDTIEKLKEKKLTPITYPQGLAMAKEIGAVKYLECSALTQRGLKTVFDEAIRAVLCPPPVKKRKRKCLLL 192          
BLAST of Rac-1 vs. Ensembl Human
Match: RAC2 (Rac family small GTPase 2 [Source:HGNC Symbol;Acc:HGNC:9802])

HSP 1 Score: 330.102 bits (845), Expect = 3.479e-111
Identity = 155/192 (80.73%), Postives = 173/192 (90.10%), Query Frame = 2
Query:  164 MQGIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDNKPVNLGLWDTAGQEDYDRLRPLSYPQTDVFLICFSLINSSSYENVRAKWYPEITHHCPNTPIILVGTKLDLRENHMNGEAGKDRRNTPISYPQGLVLAKEIGAVKYLECSALTQKGLKSVFDEAIRAVLCPKPPR--KKTCKFL 733
            MQ IKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVD+KPVNLGLWDTAGQEDYDRLRPLSYPQTDVFLICFSL++ +SYENVRAKW+PE+ HHCP+TPIILVGTKLDLR++    E  K+++  PI+YPQGL LAKEI +VKYLECSALTQ+GLK+VFDEAIRAVLCP+P R  K+ C  L
Sbjct:    1 MQAIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDSKPVNLGLWDTAGQEDYDRLRPLSYPQTDVFLICFSLVSPASYENVRAKWFPEVRHHCPSTPIILVGTKLDLRDDKDTIEKLKEKKLAPITYPQGLALAKEIDSVKYLECSALTQRGLKTVFDEAIRAVLCPQPTRQQKRACSLL 192          
BLAST of Rac-1 vs. Ensembl Human
Match: RAC1 (Rac family small GTPase 1 [Source:HGNC Symbol;Acc:HGNC:9801])

HSP 1 Score: 320.857 bits (821), Expect = 2.592e-107
Identity = 158/211 (74.88%), Postives = 173/211 (81.99%), Query Frame = 2
Query:  164 MQGIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDNKPVNLGLWDTAGQEDYDRLRPLSYPQT-------------------DVFLICFSLINSSSYENVRAKWYPEITHHCPNTPIILVGTKLDLRENHMNGEAGKDRRNTPISYPQGLVLAKEIGAVKYLECSALTQKGLKSVFDEAIRAVLCPKP--PRKKTCKFL 733
            MQ IKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVD KPVNLGLWDTAGQEDYDRLRPLSYPQT                   DVFLICFSL++ +S+ENVRAKWYPE+ HHCPNTPIILVGTKLDLR++    E  K+++ TPI+YPQGL +AKEIGAVKYLECSALTQ+GLK+VFDEAIRAVLCP P   RK+ C  L
Sbjct:    1 MQAIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDGKPVNLGLWDTAGQEDYDRLRPLSYPQTVGETYGKDITSRGKDKPIADVFLICFSLVSPASFENVRAKWYPEVRHHCPNTPIILVGTKLDLRDDKDTIEKLKEKKLTPITYPQGLAMAKEIGAVKYLECSALTQRGLKTVFDEAIRAVLCPPPVKKRKRKCLLL 211          
BLAST of Rac-1 vs. Ensembl Human
Match: RAC3 (Rac family small GTPase 3 [Source:HGNC Symbol;Acc:HGNC:9803])

HSP 1 Score: 318.546 bits (815), Expect = 1.026e-106
Identity = 147/178 (82.58%), Postives = 165/178 (92.70%), Query Frame = 2
Query:  164 MQGIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDNKPVNLGLWDTAGQEDYDRLRPLSYPQTDVFLICFSLINSSSYENVRAKWYPEITHHCPNTPIILVGTKLDLRENHMNGEAGKDRRNTPISYPQGLVLAKEIGAVKYLECSALTQKGLKSVFDEAIRAVLC 697
            MQ IKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVD KPVNLGLWDTAGQEDYDRLRPLSYPQTDVFLICFSL++ +S+ENVRAKWYPE+ HHCP+TPI+LVGTKLDLR++    E  +D++  PI+YPQGL +A+EIG+VKYLECSALTQ+GLK+VFDEAIRAVLC
Sbjct:    1 MQAIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDGKPVNLGLWDTAGQEDYDRLRPLSYPQTDVFLICFSLVSPASFENVRAKWYPEVRHHCPHTPILLVGTKLDLRDDKDTIERLRDKKLAPITYPQGLAMAREIGSVKYLECSALTQRGLKTVFDEAIRAVLC 178          
BLAST of Rac-1 vs. Ensembl Human
Match: RAC2 (Rac family small GTPase 2 [Source:HGNC Symbol;Acc:HGNC:9802])

HSP 1 Score: 308.916 bits (790), Expect = 5.209e-103
Identity = 148/192 (77.08%), Postives = 166/192 (86.46%), Query Frame = 2
Query:  164 MQGIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDNKPVNLGLWDTAGQEDYDRLRPLSYPQTDVFLICFSLINSSSYENVRAKWYPEITHHCPNTPIILVGTKLDLRENHMNGEAGKDRRNTPISYPQGLVLAKEIGAVKYLECSALTQKGLKSVFDEAIRAVLCPKPPR--KKTCKFL 733
            MQ IK       AVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVD+KPVNLGLWDTAGQEDYDRLRPLSYPQTDVFLICFSL++ +SYENVRAKW+PE+ HHCP+TPIILVGTKLDLR++    E  K+++  PI+YPQGL LAKEI +VKYLECSALTQ+GLK+VFDEAIRAVLCP+P R  K+ C  L
Sbjct:    1 MQAIK-------AVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDSKPVNLGLWDTAGQEDYDRLRPLSYPQTDVFLICFSLVSPASYENVRAKWFPEVRHHCPSTPIILVGTKLDLRDDKDTIEKLKEKKLAPITYPQGLALAKEIDSVKYLECSALTQRGLKTVFDEAIRAVLCPQPTRQQKRACSLL 185          
BLAST of Rac-1 vs. Ensembl Celegans
Match: ced-10 (Ras-related protein ced-10 [Source:UniProtKB/Swiss-Prot;Acc:Q03206])

HSP 1 Score: 315.079 bits (806), Expect = 8.855e-106
Identity = 150/188 (79.79%), Postives = 164/188 (87.23%), Query Frame = 2
Query:  164 MQGIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDNKPVNLGLWDTAGQEDYDRLRPLSYPQTDVFLICFSLINSSSYENVRAKWYPEITHHCPNTPIILVGTKLDLRENHMNGEAGKDRRNTPISYPQGLVLAKEIGAVKYLECSALTQKGLKSVFDEAIRAVLCPKPPRKKTCK 727
            MQ IKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVD +P+NLGLWDTAGQEDYDRLRPLSYPQTDVFL+CF+L N +S+ENVRAKWYPE++HHCPNTPIILVGTK DLRE+    E  ++RR  P+S  QG V+AKEI AVKYLECSALTQ+GLK VFDEAIRAVL P P R K  K
Sbjct:    1 MQAIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDGRPINLGLWDTAGQEDYDRLRPLSYPQTDVFLVCFALNNPASFENVRAKWYPEVSHHCPNTPIILVGTKADLREDRDTVERLRERRLQPVSQTQGYVMAKEIKAVKYLECSALTQRGLKQVFDEAIRAVLTP-PQRAKKSK 187          
BLAST of Rac-1 vs. Ensembl Celegans
Match: rac-2 (Ras-related protein rac-2 [Source:UniProtKB/Swiss-Prot;Acc:Q94124])

HSP 1 Score: 287.73 bits (735), Expect = 4.831e-95
Identity = 134/179 (74.86%), Postives = 152/179 (84.92%), Query Frame = 2
Query:  164 MQGIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDNKPVNLGLWDTAGQEDYDRLRPLSYPQTDVFLICFSLINSSSYENVRAKWYPEITHHCPNTPIILVGTKLDLRENHMNGEAGKDRRNTPISYPQGLVLAKEIGAVKYLECSALTQKGLKSVFDEAIRAVLCP 700
            MQ IKCVVVGDGAVGKTCLL+SYTTNAFPGEYI TVFD YS NVMVD +P+NL LWDTAGQ+DYD+ R LS+PQTDVFL+CF+L N +S+ENVRAKWYPE++HHCPNTPIILVGTK DLRE+    E  ++RR  P+S+ QG V+AKEI AVKYLECSALTQ GLK VFDEAIR  L P
Sbjct:    1 MQAIKCVVVGDGAVGKTCLLLSYTTNAFPGEYILTVFDTYSTNVMVDGRPINLSLWDTAGQDDYDQFRHLSFPQTDVFLVCFALNNPASFENVRAKWYPEVSHHCPNTPIILVGTKADLREDRDTIERLRERRLQPVSHTQGYVMAKEIKAVKYLECSALTQIGLKQVFDEAIRTGLTP 179          
BLAST of Rac-1 vs. Ensembl Celegans
Match: cdc-42 (Cell division control protein 42 homolog [Source:UniProtKB/Swiss-Prot;Acc:Q05062])

HSP 1 Score: 261.922 bits (668), Expect = 4.802e-85
Identity = 126/191 (65.97%), Postives = 149/191 (78.01%), Query Frame = 2
Query:  164 MQGIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDNKPVNLGLWDTAGQEDYDRLRPLSYPQTDVFLICFSLINSSSYENVRAKWYPEITHHCPNTPIILVGTKLDLRENHMNGEAGKDRRNTPISYPQGLVLAKEIGAVKYLECSALTQKGLKSVFDEAIRAVL-CPKPPRKKTCKFL 733
            MQ IKCVVVGDGAVGKTCLLISYTTN FP EY+PTVFDNY+  VM+  +P  LGL+DTAGQEDYDRLRPLSYPQTDVFL+CFS++  +S+ENVR KW PEI+HHC  TP +LVGT++DLR++    E     +  P+S   G  LAKE+ AVKY+ECSALTQKGLK+VFDEAI A L  P+  +KK C  L
Sbjct:    1 MQTIKCVVVGDGAVGKTCLLISYTTNKFPSEYVPTVFDNYAVTVMIGGEPYTLGLFDTAGQEDYDRLRPLSYPQTDVFLVCFSVVAPASFENVREKWVPEISHHCSKTPFLLVGTQVDLRDDPGMLEKLAKNKQKPVSTDVGEKLAKELKAVKYVECSALTQKGLKNVFDEAILAALDPPQQEKKKKCNIL 191          
BLAST of Rac-1 vs. Ensembl Celegans
Match: mig-2 (Rac-like GTPase [Source:UniProtKB/TrEMBL;Acc:G5EBV3])

HSP 1 Score: 260.766 bits (665), Expect = 1.387e-84
Identity = 119/188 (63.30%), Postives = 152/188 (80.85%), Query Frame = 2
Query:  173 IKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDNKPVNLGLWDTAGQEDYDRLRPLSYPQTDVFLICFSLINSSSYENVRAKWYPEITHHCPNTPIILVGTKLDLRENHMNGEAGKDRRNTPISYPQGLVLAKEIGAVKYLECSALTQKGLKSVFDEAIRAVLCPKP-PRKKTCKFL 733
            IKCVVVGDG VGKTC+LISYTT++FP +Y+PTVFDNYSA + +D   VNLGLWDTAGQEDYDRLRPLSYPQTDVF++CFS+++  S++NV +KW PEI  HCP+ P+ILVGTKLDLR+      A +    +PIS  QG+ +A++I AVKYLECSALTQ+GL  VF++A+R++L PKP  +KK+C  +
Sbjct:    8 IKCVVVGDGTVGKTCMLISYTTDSFPVQYVPTVFDNYSAQMSLDGNVVNLGLWDTAGQEDYDRLRPLSYPQTDVFILCFSVVSPVSFDNVASKWIPEIRQHCPDAPVILVGTKLDLRDEAEPMRALQAEGKSPISKTQGMKMAQKIKAVKYLECSALTQQGLTQVFEDAVRSILHPKPQKKKKSCNIM 195          
BLAST of Rac-1 vs. Ensembl Celegans
Match: rho-1 (Ras-like GTP-binding protein rhoA [Source:UniProtKB/Swiss-Prot;Acc:Q22038])

HSP 1 Score: 207.994 bits (528), Expect = 3.324e-64
Identity = 96/173 (55.49%), Postives = 121/173 (69.94%), Query Frame = 2
Query:  176 KCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDNKPVNLGLWDTAGQEDYDRLRPLSYPQTDVFLICFSLINSSSYENVRAKWYPEITHHCPNTPIILVGTKLDLRENHMNGEAGKDRRNTPISYPQGLVLAKEIGAVKYLECSALTQKGLKSVFDEAIRAVL 694
            K V+VGDGA GKTCLLI ++ + FP  Y+PTVF+NY A++ VD K V L LWDTAGQEDYDRLRPLSYP TDV L+CFS+ +  S EN+  KW PE+ H CPN PIILVG K DLR +          +  P+   QG  +A++IGA  YLECSA T+ G++ VF++A +A L
Sbjct:    7 KLVIVGDGACGKTCLLIVFSKDQFPDVYVPTVFENYVADIEVDGKQVELALWDTAGQEDYDRLRPLSYPDTDVILMCFSIDSPDSLENIPEKWTPEVRHFCPNVPIILVGNKRDLRSDPQTVRELAKMKQEPVKPEQGRAIAEQIGAFAYLECSAKTKDGIREVFEKATQAAL 179          
BLAST of Rac-1 vs. Ensembl Fly
Match: Rac1 (gene:FBgn0010333 transcript:FBtr0072730)

HSP 1 Score: 330.487 bits (846), Expect = 9.902e-112
Identity = 155/192 (80.73%), Postives = 172/192 (89.58%), Query Frame = 2
Query:  164 MQGIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDNKPVNLGLWDTAGQEDYDRLRPLSYPQTDVFLICFSLINSSSYENVRAKWYPEITHHCPNTPIILVGTKLDLRENHMNGEAGKDRRNTPISYPQGLVLAKEIGAVKYLECSALTQKGLKSVFDEAIRAVLCP--KPPRKKTCKFL 733
            MQ IKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVD KP+NLGLWDTAGQEDYDRLRPLSYPQTDVFLICFSL+N +S+ENVRAKWYPE+ HHCP+TPIILVGTKLDLR++    E  +D++  PI+YPQGL +AKEIGAVKYLECSALTQKGLK+VFDEAIR+VLCP  +P  K+ C  L
Sbjct:    1 MQAIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDAKPINLGLWDTAGQEDYDRLRPLSYPQTDVFLICFSLVNPASFENVRAKWYPEVRHHCPSTPIILVGTKLDLRDDKNTIEKLRDKKLAPITYPQGLAMAKEIGAVKYLECSALTQKGLKTVFDEAIRSVLCPVLQPKSKRKCALL 192          
BLAST of Rac-1 vs. Ensembl Fly
Match: Rac1 (gene:FBgn0010333 transcript:FBtr0331868)

HSP 1 Score: 330.487 bits (846), Expect = 9.902e-112
Identity = 155/192 (80.73%), Postives = 172/192 (89.58%), Query Frame = 2
Query:  164 MQGIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDNKPVNLGLWDTAGQEDYDRLRPLSYPQTDVFLICFSLINSSSYENVRAKWYPEITHHCPNTPIILVGTKLDLRENHMNGEAGKDRRNTPISYPQGLVLAKEIGAVKYLECSALTQKGLKSVFDEAIRAVLCP--KPPRKKTCKFL 733
            MQ IKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVD KP+NLGLWDTAGQEDYDRLRPLSYPQTDVFLICFSL+N +S+ENVRAKWYPE+ HHCP+TPIILVGTKLDLR++    E  +D++  PI+YPQGL +AKEIGAVKYLECSALTQKGLK+VFDEAIR+VLCP  +P  K+ C  L
Sbjct:    1 MQAIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDAKPINLGLWDTAGQEDYDRLRPLSYPQTDVFLICFSLVNPASFENVRAKWYPEVRHHCPSTPIILVGTKLDLRDDKNTIEKLRDKKLAPITYPQGLAMAKEIGAVKYLECSALTQKGLKTVFDEAIRSVLCPVLQPKSKRKCALL 192          
BLAST of Rac-1 vs. Ensembl Fly
Match: Rac2 (gene:FBgn0014011 transcript:FBtr0076867)

HSP 1 Score: 328.176 bits (840), Expect = 1.009e-110
Identity = 153/192 (79.69%), Postives = 171/192 (89.06%), Query Frame = 2
Query:  164 MQGIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDNKPVNLGLWDTAGQEDYDRLRPLSYPQTDVFLICFSLINSSSYENVRAKWYPEITHHCPNTPIILVGTKLDLRENHMNGEAGKDRRNTPISYPQGLVLAKEIGAVKYLECSALTQKGLKSVFDEAIRAVLCP--KPPRKKTCKFL 733
            MQ IKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVD KP+NLGLWDTAGQEDYDRLRPLSYPQTDVFLICFSL+N +S+ENVRAKW+PE+ HHCP+ PIILVGTKLDLR++    E  KD++ TPI+YPQGL +AKEI AVKYLECSALTQKGLK+VFDEAIR+VLCP  + P++  C  L
Sbjct:    1 MQAIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDAKPINLGLWDTAGQEDYDRLRPLSYPQTDVFLICFSLVNPASFENVRAKWFPEVRHHCPSVPIILVGTKLDLRDDKQTIEKLKDKKLTPITYPQGLAMAKEIAAVKYLECSALTQKGLKTVFDEAIRSVLCPVVRGPKRHKCALL 192          
BLAST of Rac-1 vs. Ensembl Fly
Match: Rac2 (gene:FBgn0014011 transcript:FBtr0332800)

HSP 1 Score: 328.176 bits (840), Expect = 1.009e-110
Identity = 153/192 (79.69%), Postives = 171/192 (89.06%), Query Frame = 2
Query:  164 MQGIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDNKPVNLGLWDTAGQEDYDRLRPLSYPQTDVFLICFSLINSSSYENVRAKWYPEITHHCPNTPIILVGTKLDLRENHMNGEAGKDRRNTPISYPQGLVLAKEIGAVKYLECSALTQKGLKSVFDEAIRAVLCP--KPPRKKTCKFL 733
            MQ IKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVD KP+NLGLWDTAGQEDYDRLRPLSYPQTDVFLICFSL+N +S+ENVRAKW+PE+ HHCP+ PIILVGTKLDLR++    E  KD++ TPI+YPQGL +AKEI AVKYLECSALTQKGLK+VFDEAIR+VLCP  + P++  C  L
Sbjct:    1 MQAIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDAKPINLGLWDTAGQEDYDRLRPLSYPQTDVFLICFSLVNPASFENVRAKWFPEVRHHCPSVPIILVGTKLDLRDDKQTIEKLKDKKLTPITYPQGLAMAKEIAAVKYLECSALTQKGLKTVFDEAIRSVLCPVVRGPKRHKCALL 192          
BLAST of Rac-1 vs. Ensembl Fly
Match: Cdc42 (gene:FBgn0010341 transcript:FBtr0309215)

HSP 1 Score: 275.789 bits (704), Expect = 2.036e-90
Identity = 130/191 (68.06%), Postives = 154/191 (80.63%), Query Frame = 2
Query:  164 MQGIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDNKPVNLGLWDTAGQEDYDRLRPLSYPQTDVFLICFSLINSSSYENVRAKWYPEITHHCPNTPIILVGTKLDLRENHMNGEAGKDRRNTPISYPQGLVLAKEIGAVKYLECSALTQKGLKSVFDEAIRAVL-CPKPPRKKTCKFL 733
            MQ IKCVVVGDGAVGKTCLLISYTTN FP EY+PTVFDNY+  VM+  +P  LGL+DTAGQEDYDRLRPLSYPQTDVFL+CFS+++ SS+ENV+ KW PEITHHC  TP +LVGT++DLR+ +   E     +  PI+  QG  LAKE+ AVKY+ECSALTQKGLK+VFDEAI A L  P+P +K+ CKFL
Sbjct:    1 MQTIKCVVVGDGAVGKTCLLISYTTNKFPSEYVPTVFDNYAVTVMIGGEPYTLGLFDTAGQEDYDRLRPLSYPQTDVFLVCFSVVSPSSFENVKEKWVPEITHHCQKTPFLLVGTQIDLRDENSTLEKLAKNKQKPITMEQGEKLAKELKAVKYVECSALTQKGLKNVFDEAILAALEPPEPTKKRKCKFL 191          
BLAST of Rac-1 vs. Ensembl Zebrafish
Match: rac2 (Rac family small GTPase 2 [Source:ZFIN;Acc:ZDB-GENE-040625-27])

HSP 1 Score: 330.487 bits (846), Expect = 4.066e-111
Identity = 154/188 (81.91%), Postives = 171/188 (90.96%), Query Frame = 2
Query:  164 MQGIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDNKPVNLGLWDTAGQEDYDRLRPLSYPQTDVFLICFSLINSSSYENVRAKWYPEITHHCPNTPIILVGTKLDLRENHMNGEAGKDRRNTPISYPQGLVLAKEIGAVKYLECSALTQKGLKSVFDEAIRAVLCPKPPRKKTCK 727
            MQ IKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVD+KPVNLGLWDTAGQEDYDRLRPLSYPQTDVFLICFSL++ +S+ENVRAKWYPE+ HHCP+TPIILVGTKLDLR+     E  K+++  PI+YPQGL LAKEI AVKYLECSALTQ+GLK+VFDEAIRAVLCP+P + + CK
Sbjct:    1 MQAIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDSKPVNLGLWDTAGQEDYDRLRPLSYPQTDVFLICFSLVSPASFENVRAKWYPEVRHHCPSTPIILVGTKLDLRDEKETIEKLKEKKLAPITYPQGLALAKEIDAVKYLECSALTQRGLKTVFDEAIRAVLCPQPTKIRHCK 188          
BLAST of Rac-1 vs. Ensembl Zebrafish
Match: rac3b (Rac family small GTPase 3b [Source:ZFIN;Acc:ZDB-GENE-080220-21])

HSP 1 Score: 329.331 bits (843), Expect = 4.198e-111
Identity = 153/185 (82.70%), Postives = 171/185 (92.43%), Query Frame = 2
Query:  164 MQGIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDNKPVNLGLWDTAGQEDYDRLRPLSYPQTDVFLICFSLINSSSYENVRAKWYPEITHHCPNTPIILVGTKLDLRENHMNGEAGKDRRNTPISYPQGLVLAKEIGAVKYLECSALTQKGLKSVFDEAIRAVLCPKPPRKK 718
            MQ IKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVD KPVNLGLWDTAGQEDYDRLRPLSYPQTDVFLICFSL++ +S+ENVRAKWYPE+ HHCPNTPIILVGTKLDLR++    E  +D++ +PI+YPQGL +A+EIGAVKYLECSALTQ+GLK+VFDEAIRAVLCP P +K+
Sbjct:    1 MQAIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDGKPVNLGLWDTAGQEDYDRLRPLSYPQTDVFLICFSLVSPASFENVRAKWYPEVRHHCPNTPIILVGTKLDLRDDKDTIERLRDKKLSPITYPQGLAMAREIGAVKYLECSALTQRGLKTVFDEAIRAVLCPPPVKKR 185          
BLAST of Rac-1 vs. Ensembl Zebrafish
Match: rac3a (Rac family small GTPase 3a [Source:ZFIN;Acc:ZDB-GENE-040718-256])

HSP 1 Score: 328.946 bits (842), Expect = 5.813e-111
Identity = 153/185 (82.70%), Postives = 170/185 (91.89%), Query Frame = 2
Query:  164 MQGIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDNKPVNLGLWDTAGQEDYDRLRPLSYPQTDVFLICFSLINSSSYENVRAKWYPEITHHCPNTPIILVGTKLDLRENHMNGEAGKDRRNTPISYPQGLVLAKEIGAVKYLECSALTQKGLKSVFDEAIRAVLCPKPPRKK 718
            MQ IKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVD KPVNLGLWDTAGQEDYDRLRPLSYPQTDVFLICFSL++ +S+ENVRAKWYPE+ HHCPNTPIILVGTKLDLR++    E  +D++  PI+YPQGL +A+EIGAVKYLECSALTQ+GLK+VFDEAIRAVLCP P +K+
Sbjct:    1 MQAIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDGKPVNLGLWDTAGQEDYDRLRPLSYPQTDVFLICFSLVSPASFENVRAKWYPEVRHHCPNTPIILVGTKLDLRDDKDTIERLRDKKLAPITYPQGLAMAREIGAVKYLECSALTQRGLKTVFDEAIRAVLCPPPVKKR 185          
BLAST of Rac-1 vs. Ensembl Zebrafish
Match: rac1a (Rac family small GTPase 1a [Source:ZFIN;Acc:ZDB-GENE-030131-5415])

HSP 1 Score: 328.946 bits (842), Expect = 5.877e-111
Identity = 154/181 (85.08%), Postives = 168/181 (92.82%), Query Frame = 2
Query:  164 MQGIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDNKPVNLGLWDTAGQEDYDRLRPLSYPQTDVFLICFSLINSSSYENVRAKWYPEITHHCPNTPIILVGTKLDLRENHMNGEAGKDRRNTPISYPQGLVLAKEIGAVKYLECSALTQKGLKSVFDEAIRAVLCPKP 706
            MQ IKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVD KPVNLGLWDTAGQEDYDRLRPLSYPQTDVFLICFSL++ +S+ENVRAKWYPE+ HHCPNTPIILVGTKLDLR++    E  K+++ TPI+YPQGL +AKEIGAVKYLECSALTQ+GLK+VFDEAIRAVLCP P
Sbjct:    1 MQAIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDGKPVNLGLWDTAGQEDYDRLRPLSYPQTDVFLICFSLVSPASFENVRAKWYPEVRHHCPNTPIILVGTKLDLRDDKDTIEKLKEKKLTPITYPQGLAMAKEIGAVKYLECSALTQRGLKTVFDEAIRAVLCPPP 181          
BLAST of Rac-1 vs. Ensembl Zebrafish
Match: rac2 (Rac family small GTPase 2 [Source:ZFIN;Acc:ZDB-GENE-040625-27])

HSP 1 Score: 328.946 bits (842), Expect = 6.204e-111
Identity = 156/192 (81.25%), Postives = 172/192 (89.58%), Query Frame = 2
Query:  164 MQGIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDNKPVNLGLWDTAGQEDYDRLRPLSYPQTDVFLICFSLINSSSYENVRAKWYPEITHHCPNTPIILVGTKLDLRENHMNGEAGKDRRNTPISYPQGLVLAKEIGAVKYLECSALTQKGLKSVFDEAIRAVLCPKPP--RKKTCKFL 733
            MQ IKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVD+KPVNLGLWDTAGQEDYDRLRPLSYPQTDVFLICFSL++ +S+ENVRAKWYPE+ HHCP+TPIILVGTKLDLR+     E  K+++  PI+YPQGL LAKEI AVKYLECSALTQ+GLK+VFDEAIRAVLCP+P   +KK C  L
Sbjct:    1 MQAIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDSKPVNLGLWDTAGQEDYDRLRPLSYPQTDVFLICFSLVSPASFENVRAKWYPEVRHHCPSTPIILVGTKLDLRDEKETIEKLKEKKLAPITYPQGLALAKEIDAVKYLECSALTQRGLKTVFDEAIRAVLCPQPTKVKKKGCVML 192          
BLAST of Rac-1 vs. Ensembl Xenopus
Match: rac1 (Rac family small GTPase 1 [Source:NCBI gene;Acc:448118])

HSP 1 Score: 332.413 bits (851), Expect = 4.237e-112
Identity = 158/192 (82.29%), Postives = 173/192 (90.10%), Query Frame = 2
Query:  164 MQGIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDNKPVNLGLWDTAGQEDYDRLRPLSYPQTDVFLICFSLINSSSYENVRAKWYPEITHHCPNTPIILVGTKLDLRENHMNGEAGKDRRNTPISYPQGLVLAKEIGAVKYLECSALTQKGLKSVFDEAIRAVLCPKP--PRKKTCKFL 733
            MQ IKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVD KPVNLGLWDTAGQEDYDRLRPLSYPQTDVFLICFSL++ +S+ENVRAKWYPE+ HHCPNTPIILVGTKLDLR++    E  K+++ TPI+YPQGL +AKEIGAVKYLECSALTQ+GLK+VFDEAIRAVLCP P   RK+ C  L
Sbjct:    1 MQAIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDGKPVNLGLWDTAGQEDYDRLRPLSYPQTDVFLICFSLVSPASFENVRAKWYPEVRHHCPNTPIILVGTKLDLRDDKDTIEKLKEKKLTPITYPQGLAMAKEIGAVKYLECSALTQRGLKTVFDEAIRAVLCPPPVKKRKRKCLLL 192          
BLAST of Rac-1 vs. Ensembl Xenopus
Match: yju2 (YJU2 splicing factor homolog [Source:Xenbase;Acc:XB-GENE-5938025])

HSP 1 Score: 330.102 bits (845), Expect = 2.861e-111
Identity = 158/192 (82.29%), Postives = 172/192 (89.58%), Query Frame = 2
Query:  164 MQGIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDNKPVNLGLWDTAGQEDYDRLRPLSYPQTDVFLICFSLINSSSYENVRAKWYPEITHHCPNTPIILVGTKLDLRENHMNGEAGKDRRNTPISYPQGLVLAKEIGAVKYLECSALTQKGLKSVFDEAIRAVLCPKP--PRKKTCKFL 733
            MQ IKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVD+KPVNLGLWDTAGQEDYDRLRPLSYPQTDVFLICFSL++ +SYENVRAKWYPE+ HHCP+TPIILVGTKLDLR++    E  K+++ +PISYPQGL LAKEI AVKYLECSALTQ+GLK+VFDEAIRAVLCP P  P K  C  L
Sbjct:    1 MQAIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDSKPVNLGLWDTAGQEDYDRLRPLSYPQTDVFLICFSLVSPASYENVRAKWYPEVRHHCPSTPIILVGTKLDLRDDKETIEKLKEKKLSPISYPQGLALAKEIEAVKYLECSALTQRGLKTVFDEAIRAVLCPPPSRPNKAKCVVL 192          
BLAST of Rac-1 vs. Ensembl Xenopus
Match: nab2 (NGFI-A binding protein 2 (EGR1 binding protein 2) [Source:Xenbase;Acc:XB-GENE-957953])

HSP 1 Score: 328.176 bits (840), Expect = 1.440e-110
Identity = 155/188 (82.45%), Postives = 172/188 (91.49%), Query Frame = 2
Query:  164 MQGIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDNKPVNLGLWDTAGQEDYDRLRPLSYPQTDVFLICFSLINSSSYENVRAKWYPEITHHCPNTPIILVGTKLDLRENHMNGEAGKDRRNTPISYPQGLVLAKEIGAVKYLECSALTQKGLKSVFDEAIRAVLCPKPPRKKTCK 727
            MQ IKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVD KPVNLGLWDTAGQEDYDRLRPLSYPQTDVFLICFSL++ +S+ENVRAKWYPE+ HHCPNTPIILVGTKLDLR++    E  +D+R +PI+YPQGL +A+EIG+VKYLECSALTQ+GLK+VFDEAIRAVLCP PP K+  K
Sbjct:    1 MQAIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDGKPVNLGLWDTAGQEDYDRLRPLSYPQTDVFLICFSLVSPASFENVRAKWYPEVRHHCPNTPIILVGTKLDLRDDKDTIERLRDKRLSPITYPQGLAMAREIGSVKYLECSALTQRGLKTVFDEAIRAVLCP-PPVKRAGK 187          
BLAST of Rac-1 vs. Ensembl Xenopus
Match: nab2 (NGFI-A binding protein 2 (EGR1 binding protein 2) [Source:Xenbase;Acc:XB-GENE-957953])

HSP 1 Score: 312.383 bits (799), Expect = 2.311e-104
Identity = 147/186 (79.03%), Postives = 168/186 (90.32%), Query Frame = 2
Query:  170 GIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDNKPVNLGLWDTAGQEDYDRLRPLSYPQTDVFLICFSLINSSSYENVRAKWYPEITHHCPNTPIILVGTKLDLRENHMNGEAGKDRRNTPISYPQGLVLAKEIGAVKYLECSALTQKGLKSVFDEAIRAVLCPKPPRKKTCK 727
             ++CV++  GAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVD KPVNLGLWDTAGQEDYDRLRPLSYPQTDVFLICFSL++ +S+ENVRAKWYPE+ HHCPNTPIILVGTKLDLR++    E  +D+R +PI+YPQGL +A+EIG+VKYLECSALTQ+GLK+VFDEAIRAVLCP PP K+  K
Sbjct:    3 SLRCVIICWGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDGKPVNLGLWDTAGQEDYDRLRPLSYPQTDVFLICFSLVSPASFENVRAKWYPEVRHHCPNTPIILVGTKLDLRDDKDTIERLRDKRLSPITYPQGLAMAREIGSVKYLECSALTQRGLKTVFDEAIRAVLCP-PPVKRAGK 187          
BLAST of Rac-1 vs. Ensembl Xenopus
Match: yju2 (YJU2 splicing factor homolog [Source:Xenbase;Acc:XB-GENE-5938025])

HSP 1 Score: 306.22 bits (783), Expect = 5.775e-102
Identity = 147/180 (81.67%), Postives = 161/180 (89.44%), Query Frame = 2
Query:  200 AVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDNKPVNLGLWDTAGQEDYDRLRPLSYPQTDVFLICFSLINSSSYENVRAKWYPEITHHCPNTPIILVGTKLDLRENHMNGEAGKDRRNTPISYPQGLVLAKEIGAVKYLECSALTQKGLKSVFDEAIRAVLCPKP--PRKKTCKFL 733
            AVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVD+KPVNLGLWDTAGQEDYDRLRPLSYPQTDVFLICFSL++ +SYENVRAKWYPE+ HHCP+TPIILVGTKLDLR++    E  K+++ +PISYPQGL LAKEI AVKYLECSALTQ+GLK+VFDEAIRAVLCP P  P K  C  L
Sbjct:   12 AVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDSKPVNLGLWDTAGQEDYDRLRPLSYPQTDVFLICFSLVSPASYENVRAKWYPEVRHHCPSTPIILVGTKLDLRDDKETIEKLKEKKLSPISYPQGLALAKEIEAVKYLECSALTQRGLKTVFDEAIRAVLCPPPSRPNKAKCVVL 191          
BLAST of Rac-1 vs. Ensembl Mouse
Match: Rac1 (Rac family small GTPase 1 [Source:MGI Symbol;Acc:MGI:97845])

HSP 1 Score: 332.413 bits (851), Expect = 3.209e-112
Identity = 158/192 (82.29%), Postives = 173/192 (90.10%), Query Frame = 2
Query:  164 MQGIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDNKPVNLGLWDTAGQEDYDRLRPLSYPQTDVFLICFSLINSSSYENVRAKWYPEITHHCPNTPIILVGTKLDLRENHMNGEAGKDRRNTPISYPQGLVLAKEIGAVKYLECSALTQKGLKSVFDEAIRAVLCPKP--PRKKTCKFL 733
            MQ IKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVD KPVNLGLWDTAGQEDYDRLRPLSYPQTDVFLICFSL++ +S+ENVRAKWYPE+ HHCPNTPIILVGTKLDLR++    E  K+++ TPI+YPQGL +AKEIGAVKYLECSALTQ+GLK+VFDEAIRAVLCP P   RK+ C  L
Sbjct:    1 MQAIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDGKPVNLGLWDTAGQEDYDRLRPLSYPQTDVFLICFSLVSPASFENVRAKWYPEVRHHCPNTPIILVGTKLDLRDDKDTIEKLKEKKLTPITYPQGLAMAKEIGAVKYLECSALTQRGLKTVFDEAIRAVLCPPPVKKRKRKCLLL 192          
BLAST of Rac-1 vs. Ensembl Mouse
Match: Rac2 (Rac family small GTPase 2 [Source:MGI Symbol;Acc:MGI:97846])

HSP 1 Score: 327.405 bits (838), Expect = 2.714e-110
Identity = 154/192 (80.21%), Postives = 173/192 (90.10%), Query Frame = 2
Query:  164 MQGIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDNKPVNLGLWDTAGQEDYDRLRPLSYPQTDVFLICFSLINSSSYENVRAKWYPEITHHCPNTPIILVGTKLDLRENHMNGEAGKDRRNTPISYPQGLVLAKEIGAVKYLECSALTQKGLKSVFDEAIRAVLCPKPPR--KKTCKFL 733
            MQ IKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVD+KPVNLGLWDTAGQEDYDRLRPLSYPQTDVFLICFSL++ +SYENVRAKW+PE+ HHCP+TPIILVGTKLDLR++    E  K+++  PI+YPQGL LAK+I +VKYLECSALTQ+GLK+VFDEAIRAVLCP+P R  K+ C  L
Sbjct:    1 MQAIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDSKPVNLGLWDTAGQEDYDRLRPLSYPQTDVFLICFSLVSPASYENVRAKWFPEVRHHCPSTPIILVGTKLDLRDDKDTIEKLKEKKLAPITYPQGLALAKDIDSVKYLECSALTQRGLKTVFDEAIRAVLCPQPTRQQKRPCSLL 192          
BLAST of Rac-1 vs. Ensembl Mouse
Match: Rac1 (Rac family small GTPase 1 [Source:MGI Symbol;Acc:MGI:97845])

HSP 1 Score: 319.701 bits (818), Expect = 4.470e-107
Identity = 157/209 (75.12%), Postives = 173/209 (82.78%), Query Frame = 2
Query:  164 MQGIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDNKPVNLGLWDTAGQEDYDRLRPLSYPQT-------------------DVFLICFSLINSSSYENVRAKWYPEITHHCPNTPIILVGTKLDLRENHMNGEAGKDRRNTPISYPQGLVLAKEIGAVKYLECSALTQKGLKSVFDEAIRAVLCPKPPRKKTCKFL 733
            MQ IKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVD KPVNLGLWDTAGQEDYDRLRPLSYPQT                   DVFLICFSL++ +S+ENVRAKWYPE+ HHCPNTPIILVGTKLDLR++    E  K+++ TPI+YPQGL +AKEIGAVKYLECSALTQ+GLK+VFDEAIRAVLCP P +K+  K L
Sbjct:    1 MQAIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDGKPVNLGLWDTAGQEDYDRLRPLSYPQTVGDTCGKDRPSRGKDKPIADVFLICFSLVSPASFENVRAKWYPEVRHHCPNTPIILVGTKLDLRDDKDTIEKLKEKKLTPITYPQGLAMAKEIGAVKYLECSALTQRGLKTVFDEAIRAVLCPPPVKKRKRKCL 209          
BLAST of Rac-1 vs. Ensembl Mouse
Match: Rac3 (Rac family small GTPase 3 [Source:MGI Symbol;Acc:MGI:2180784])

HSP 1 Score: 318.546 bits (815), Expect = 7.042e-107
Identity = 147/178 (82.58%), Postives = 165/178 (92.70%), Query Frame = 2
Query:  164 MQGIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDNKPVNLGLWDTAGQEDYDRLRPLSYPQTDVFLICFSLINSSSYENVRAKWYPEITHHCPNTPIILVGTKLDLRENHMNGEAGKDRRNTPISYPQGLVLAKEIGAVKYLECSALTQKGLKSVFDEAIRAVLC 697
            MQ IKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVD KPVNLGLWDTAGQEDYDRLRPLSYPQTDVFLICFSL++ +S+ENVRAKWYPE+ HHCP+TPI+LVGTKLDLR++    E  +D++  PI+YPQGL +A+EIG+VKYLECSALTQ+GLK+VFDEAIRAVLC
Sbjct:    1 MQAIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDGKPVNLGLWDTAGQEDYDRLRPLSYPQTDVFLICFSLVSPASFENVRAKWYPEVRHHCPHTPILLVGTKLDLRDDKDTIERLRDKKLAPITYPQGLAMAREIGSVKYLECSALTQRGLKTVFDEAIRAVLC 178          
BLAST of Rac-1 vs. Ensembl Mouse
Match: Rac3 (Rac family small GTPase 3 [Source:MGI Symbol;Acc:MGI:2180784])

HSP 1 Score: 295.819 bits (756), Expect = 3.955e-98
Identity = 136/166 (81.93%), Postives = 154/166 (92.77%), Query Frame = 2
Query:  200 AVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDNKPVNLGLWDTAGQEDYDRLRPLSYPQTDVFLICFSLINSSSYENVRAKWYPEITHHCPNTPIILVGTKLDLRENHMNGEAGKDRRNTPISYPQGLVLAKEIGAVKYLECSALTQKGLKSVFDEAIRAVLC 697
            AVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVD KPVNLGLWDTAGQEDYDRLRPLSYPQTDVFLICFSL++ +S+ENVRAKWYPE+ HHCP+TPI+LVGTKLDLR++    E  +D++  PI+YPQGL +A+EIG+VKYLECSALTQ+GLK+VFDEAIRAVLC
Sbjct:    6 AVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDGKPVNLGLWDTAGQEDYDRLRPLSYPQTDVFLICFSLVSPASFENVRAKWYPEVRHHCPHTPILLVGTKLDLRDDKDTIERLRDKKLAPITYPQGLAMAREIGSVKYLECSALTQRGLKTVFDEAIRAVLC 171          
BLAST of Rac-1 vs. UniProt/SwissProt
Match: sp|Q6RUV5|RAC1_RAT (Ras-related C3 botulinum toxin substrate 1 OS=Rattus norvegicus OX=10116 GN=Rac1 PE=1 SV=1)

HSP 1 Score: 332.413 bits (851), Expect = 2.245e-111
Identity = 158/192 (82.29%), Postives = 173/192 (90.10%), Query Frame = 2
Query:  164 MQGIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDNKPVNLGLWDTAGQEDYDRLRPLSYPQTDVFLICFSLINSSSYENVRAKWYPEITHHCPNTPIILVGTKLDLRENHMNGEAGKDRRNTPISYPQGLVLAKEIGAVKYLECSALTQKGLKSVFDEAIRAVLCPKP--PRKKTCKFL 733
            MQ IKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVD KPVNLGLWDTAGQEDYDRLRPLSYPQTDVFLICFSL++ +S+ENVRAKWYPE+ HHCPNTPIILVGTKLDLR++    E  K+++ TPI+YPQGL +AKEIGAVKYLECSALTQ+GLK+VFDEAIRAVLCP P   RK+ C  L
Sbjct:    1 MQAIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDGKPVNLGLWDTAGQEDYDRLRPLSYPQTDVFLICFSLVSPASFENVRAKWYPEVRHHCPNTPIILVGTKLDLRDDKDTIEKLKEKKLTPITYPQGLAMAKEIGAVKYLECSALTQRGLKTVFDEAIRAVLCPPPVKKRKRKCLLL 192          
BLAST of Rac-1 vs. UniProt/SwissProt
Match: sp|P63001|RAC1_MOUSE (Ras-related C3 botulinum toxin substrate 1 OS=Mus musculus OX=10090 GN=Rac1 PE=1 SV=1)

HSP 1 Score: 332.413 bits (851), Expect = 2.245e-111
Identity = 158/192 (82.29%), Postives = 173/192 (90.10%), Query Frame = 2
Query:  164 MQGIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDNKPVNLGLWDTAGQEDYDRLRPLSYPQTDVFLICFSLINSSSYENVRAKWYPEITHHCPNTPIILVGTKLDLRENHMNGEAGKDRRNTPISYPQGLVLAKEIGAVKYLECSALTQKGLKSVFDEAIRAVLCPKP--PRKKTCKFL 733
            MQ IKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVD KPVNLGLWDTAGQEDYDRLRPLSYPQTDVFLICFSL++ +S+ENVRAKWYPE+ HHCPNTPIILVGTKLDLR++    E  K+++ TPI+YPQGL +AKEIGAVKYLECSALTQ+GLK+VFDEAIRAVLCP P   RK+ C  L
Sbjct:    1 MQAIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDGKPVNLGLWDTAGQEDYDRLRPLSYPQTDVFLICFSLVSPASFENVRAKWYPEVRHHCPNTPIILVGTKLDLRDDKDTIEKLKEKKLTPITYPQGLAMAKEIGAVKYLECSALTQRGLKTVFDEAIRAVLCPPPVKKRKRKCLLL 192          
BLAST of Rac-1 vs. UniProt/SwissProt
Match: sp|P63000|RAC1_HUMAN (Ras-related C3 botulinum toxin substrate 1 OS=Homo sapiens OX=9606 GN=RAC1 PE=1 SV=1)

HSP 1 Score: 332.413 bits (851), Expect = 2.245e-111
Identity = 158/192 (82.29%), Postives = 173/192 (90.10%), Query Frame = 2
Query:  164 MQGIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDNKPVNLGLWDTAGQEDYDRLRPLSYPQTDVFLICFSLINSSSYENVRAKWYPEITHHCPNTPIILVGTKLDLRENHMNGEAGKDRRNTPISYPQGLVLAKEIGAVKYLECSALTQKGLKSVFDEAIRAVLCPKP--PRKKTCKFL 733
            MQ IKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVD KPVNLGLWDTAGQEDYDRLRPLSYPQTDVFLICFSL++ +S+ENVRAKWYPE+ HHCPNTPIILVGTKLDLR++    E  K+++ TPI+YPQGL +AKEIGAVKYLECSALTQ+GLK+VFDEAIRAVLCP P   RK+ C  L
Sbjct:    1 MQAIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDGKPVNLGLWDTAGQEDYDRLRPLSYPQTDVFLICFSLVSPASFENVRAKWYPEVRHHCPNTPIILVGTKLDLRDDKDTIEKLKEKKLTPITYPQGLAMAKEIGAVKYLECSALTQRGLKTVFDEAIRAVLCPPPVKKRKRKCLLL 192          
BLAST of Rac-1 vs. UniProt/SwissProt
Match: sp|P62999|RAC1_CANLF (Ras-related C3 botulinum toxin substrate 1 OS=Canis lupus familiaris OX=9615 GN=RAC1 PE=2 SV=1)

HSP 1 Score: 332.413 bits (851), Expect = 2.245e-111
Identity = 158/192 (82.29%), Postives = 173/192 (90.10%), Query Frame = 2
Query:  164 MQGIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDNKPVNLGLWDTAGQEDYDRLRPLSYPQTDVFLICFSLINSSSYENVRAKWYPEITHHCPNTPIILVGTKLDLRENHMNGEAGKDRRNTPISYPQGLVLAKEIGAVKYLECSALTQKGLKSVFDEAIRAVLCPKP--PRKKTCKFL 733
            MQ IKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVD KPVNLGLWDTAGQEDYDRLRPLSYPQTDVFLICFSL++ +S+ENVRAKWYPE+ HHCPNTPIILVGTKLDLR++    E  K+++ TPI+YPQGL +AKEIGAVKYLECSALTQ+GLK+VFDEAIRAVLCP P   RK+ C  L
Sbjct:    1 MQAIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDGKPVNLGLWDTAGQEDYDRLRPLSYPQTDVFLICFSLVSPASFENVRAKWYPEVRHHCPNTPIILVGTKLDLRDDKDTIEKLKEKKLTPITYPQGLAMAKEIGAVKYLECSALTQRGLKTVFDEAIRAVLCPPPVKKRKRKCLLL 192          
BLAST of Rac-1 vs. UniProt/SwissProt
Match: sp|P62998|RAC1_BOVIN (Ras-related C3 botulinum toxin substrate 1 OS=Bos taurus OX=9913 GN=RAC1 PE=1 SV=1)

HSP 1 Score: 332.413 bits (851), Expect = 2.245e-111
Identity = 158/192 (82.29%), Postives = 173/192 (90.10%), Query Frame = 2
Query:  164 MQGIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDNKPVNLGLWDTAGQEDYDRLRPLSYPQTDVFLICFSLINSSSYENVRAKWYPEITHHCPNTPIILVGTKLDLRENHMNGEAGKDRRNTPISYPQGLVLAKEIGAVKYLECSALTQKGLKSVFDEAIRAVLCPKP--PRKKTCKFL 733
            MQ IKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVD KPVNLGLWDTAGQEDYDRLRPLSYPQTDVFLICFSL++ +S+ENVRAKWYPE+ HHCPNTPIILVGTKLDLR++    E  K+++ TPI+YPQGL +AKEIGAVKYLECSALTQ+GLK+VFDEAIRAVLCP P   RK+ C  L
Sbjct:    1 MQAIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDGKPVNLGLWDTAGQEDYDRLRPLSYPQTDVFLICFSLVSPASFENVRAKWYPEVRHHCPNTPIILVGTKLDLRDDKDTIEKLKEKKLTPITYPQGLAMAKEIGAVKYLECSALTQRGLKTVFDEAIRAVLCPPPVKKRKRKCLLL 192          
BLAST of Rac-1 vs. TrEMBL
Match: F1AGC0 (Rac-1 (Fragment) OS=Schmidtea mediterranea OX=79327 PE=2 SV=1)

HSP 1 Score: 349.362 bits (895), Expect = 4.662e-116
Identity = 167/167 (100.00%), Postives = 167/167 (100.00%), Query Frame = 2
Query:  185 VVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDNKPVNLGLWDTAGQEDYDRLRPLSYPQTDVFLICFSLINSSSYENVRAKWYPEITHHCPNTPIILVGTKLDLRENHMNGEAGKDRRNTPISYPQGLVLAKEIGAVKYLECSALTQKGLKSVFDEAIR 685
            VVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDNKPVNLGLWDTAGQEDYDRLRPLSYPQTDVFLICFSLINSSSYENVRAKWYPEITHHCPNTPIILVGTKLDLRENHMNGEAGKDRRNTPISYPQGLVLAKEIGAVKYLECSALTQKGLKSVFDEAIR
Sbjct:    1 VVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDNKPVNLGLWDTAGQEDYDRLRPLSYPQTDVFLICFSLINSSSYENVRAKWYPEITHHCPNTPIILVGTKLDLRENHMNGEAGKDRRNTPISYPQGLVLAKEIGAVKYLECSALTQKGLKSVFDEAIR 167          
BLAST of Rac-1 vs. TrEMBL
Match: A0A087UI47 (Ras-related C3 botulinum toxin substrate 1 (Fragment) OS=Stegodyphus mimosarum OX=407821 GN=X975_18775 PE=4 SV=1)

HSP 1 Score: 338.961 bits (868), Expect = 1.775e-111
Identity = 160/192 (83.33%), Postives = 175/192 (91.15%), Query Frame = 2
Query:  164 MQGIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDNKPVNLGLWDTAGQEDYDRLRPLSYPQTDVFLICFSLINSSSYENVRAKWYPEITHHCPNTPIILVGTKLDLRENHMNGEAGKDRRNTPISYPQGLVLAKEIGAVKYLECSALTQKGLKSVFDEAIRAVLC--PKPPRKKTCKFL 733
            MQ IKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVD KP+NLGLWDTAGQEDYDRLRPLSYPQTDVFLICFSL+N +S+ENVRAKWYPE++HHCPNTPIILVGTKLDLRE+    E  K+R+  PI+YPQGL +AKEIGAVKYLECSALTQKGLK+VFDEAIRAVLC  PKP ++K C+ L
Sbjct:    1 MQAIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDGKPINLGLWDTAGQEDYDRLRPLSYPQTDVFLICFSLVNPASFENVRAKWYPEVSHHCPNTPIILVGTKLDLREDKETIEKLKERKLAPITYPQGLAMAKEIGAVKYLECSALTQKGLKNVFDEAIRAVLCPQPKPKKRKHCRLL 192          
BLAST of Rac-1 vs. TrEMBL
Match: A0A131XE62 (Putative ras-related c3 botulinum toxin substrate 1 OS=Hyalomma excavatum OX=257692 PE=2 SV=1)

HSP 1 Score: 337.035 bits (863), Expect = 8.293e-111
Identity = 159/192 (82.81%), Postives = 174/192 (90.62%), Query Frame = 2
Query:  164 MQGIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDNKPVNLGLWDTAGQEDYDRLRPLSYPQTDVFLICFSLINSSSYENVRAKWYPEITHHCPNTPIILVGTKLDLRENHMNGEAGKDRRNTPISYPQGLVLAKEIGAVKYLECSALTQKGLKSVFDEAIRAVLC--PKPPRKKTCKFL 733
            MQ IKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVD KP+NLGLWDTAGQEDYDRLRPLSYPQTDVFLICFSL+N +S+ENVRAKWYPE++HHCPNTPIILVGTKLDLRE+    E  +DR+  PI+YPQGL +AKEIGAVKYLECSALTQKGLK+VFDEAIRAVLC  PKP +++ C  L
Sbjct:    1 MQAIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDGKPINLGLWDTAGQEDYDRLRPLSYPQTDVFLICFSLVNPASFENVRAKWYPEVSHHCPNTPIILVGTKLDLREDKDTVEKLRDRKLAPITYPQGLAMAKEIGAVKYLECSALTQKGLKNVFDEAIRAVLCPQPKPKKRRPCSLL 192          
BLAST of Rac-1 vs. TrEMBL
Match: A0A1E1X0F3 (Putative ras-related c3 botulinum toxin substrate 1 OS=Amblyomma aureolatum OX=187763 PE=2 SV=1)

HSP 1 Score: 337.035 bits (863), Expect = 8.293e-111
Identity = 159/192 (82.81%), Postives = 174/192 (90.62%), Query Frame = 2
Query:  164 MQGIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDNKPVNLGLWDTAGQEDYDRLRPLSYPQTDVFLICFSLINSSSYENVRAKWYPEITHHCPNTPIILVGTKLDLRENHMNGEAGKDRRNTPISYPQGLVLAKEIGAVKYLECSALTQKGLKSVFDEAIRAVLC--PKPPRKKTCKFL 733
            MQ IKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVD KP+NLGLWDTAGQEDYDRLRPLSYPQTDVFLICFSL+N +S+ENVRAKWYPE++HHCPNTPIILVGTKLDLRE+    E  +DR+  PI+YPQGL +AKEIGAVKYLECSALTQKGLK+VFDEAIRAVLC  PKP +++ C  L
Sbjct:    1 MQAIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDGKPINLGLWDTAGQEDYDRLRPLSYPQTDVFLICFSLVNPASFENVRAKWYPEVSHHCPNTPIILVGTKLDLREDKDTVEKLRDRKLAPITYPQGLAMAKEIGAVKYLECSALTQKGLKNVFDEAIRAVLCPQPKPKKRRPCSLL 192          
BLAST of Rac-1 vs. TrEMBL
Match: A0A023GI74 (Putative ras-related c3 botulinum toxin substrate 1 OS=Amblyomma triste OX=251400 PE=2 SV=1)

HSP 1 Score: 337.035 bits (863), Expect = 8.293e-111
Identity = 159/192 (82.81%), Postives = 174/192 (90.62%), Query Frame = 2
Query:  164 MQGIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDNKPVNLGLWDTAGQEDYDRLRPLSYPQTDVFLICFSLINSSSYENVRAKWYPEITHHCPNTPIILVGTKLDLRENHMNGEAGKDRRNTPISYPQGLVLAKEIGAVKYLECSALTQKGLKSVFDEAIRAVLC--PKPPRKKTCKFL 733
            MQ IKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVD KP+NLGLWDTAGQEDYDRLRPLSYPQTDVFLICFSL+N +S+ENVRAKWYPE++HHCPNTPIILVGTKLDLRE+    E  +DR+  PI+YPQGL +AKEIGAVKYLECSALTQKGLK+VFDEAIRAVLC  PKP +++ C  L
Sbjct:    1 MQAIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDGKPINLGLWDTAGQEDYDRLRPLSYPQTDVFLICFSLVNPASFENVRAKWYPEVSHHCPNTPIILVGTKLDLREDKDTVEKLRDRKLAPITYPQGLAMAKEIGAVKYLECSALTQKGLKNVFDEAIRAVLCPQPKPKKRRPCSLL 192          
BLAST of Rac-1 vs. Ensembl Cavefish
Match: rac1b (ras-related C3 botulinum toxin substrate 1-like [Source:NCBI gene;Acc:111192975])

HSP 1 Score: 335.109 bits (858), Expect = 2.099e-113
Identity = 159/192 (82.81%), Postives = 173/192 (90.10%), Query Frame = 2
Query:  164 MQGIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDNKPVNLGLWDTAGQEDYDRLRPLSYPQTDVFLICFSLINSSSYENVRAKWYPEITHHCPNTPIILVGTKLDLRENHMNGEAGKDRRNTPISYPQGLVLAKEIGAVKYLECSALTQKGLKSVFDEAIRAVLCPKP--PRKKTCKFL 733
            MQ IKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVD KPVNLGLWDTAGQEDYDRLRPLSYPQTDVFLICFSL++ +S+ENVRAKWYPE+ HHCPNTPIILVGTKLDLR++    E  K+R+ TPI+YPQGL +AKEIGAVKYLECSALTQ+GLK+VFDEAIRAVLCP P   RK+ C  L
Sbjct:    1 MQAIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDGKPVNLGLWDTAGQEDYDRLRPLSYPQTDVFLICFSLVSPASFENVRAKWYPEVRHHCPNTPIILVGTKLDLRDDQDTIEKLKERKLTPITYPQGLAMAKEIGAVKYLECSALTQRGLKTVFDEAIRAVLCPPPVKSRKRKCTLL 192          
BLAST of Rac-1 vs. Ensembl Cavefish
Match: rac1b (ras-related C3 botulinum toxin substrate 1-like [Source:NCBI gene;Acc:111192975])

HSP 1 Score: 332.413 bits (851), Expect = 1.880e-112
Identity = 158/192 (82.29%), Postives = 172/192 (89.58%), Query Frame = 2
Query:  164 MQGIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDNKPVNLGLWDTAGQEDYDRLRPLSYPQTDVFLICFSLINSSSYENVRAKWYPEITHHCPNTPIILVGTKLDLRENHMNGEAGKDRRNTPISYPQGLVLAKEIGAVKYLECSALTQKGLKSVFDEAIRAVLCPKP--PRKKTCKFL 733
            MQ IKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVD KPVNLGLWDTAGQEDYDRLRPLSYPQTDVFLICFSL++ +S+ENVRAKWYPE+ HHCPNTPIILVGTKLDLR++    E  K+R+ TPI+YPQGL +AKEIGAVKYLECSALTQ+ LK+VFDEAIRAVLCP P   RK+ C  L
Sbjct:    1 MQAIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDGKPVNLGLWDTAGQEDYDRLRPLSYPQTDVFLICFSLVSPASFENVRAKWYPEVRHHCPNTPIILVGTKLDLRDDQDTIEKLKERKLTPITYPQGLAMAKEIGAVKYLECSALTQRDLKTVFDEAIRAVLCPPPVKSRKRKCTLL 192          
BLAST of Rac-1 vs. Ensembl Cavefish
Match: rac1b (ras-related C3 botulinum toxin substrate 1-like [Source:NCBI gene;Acc:111192975])

HSP 1 Score: 332.413 bits (851), Expect = 1.880e-112
Identity = 158/192 (82.29%), Postives = 172/192 (89.58%), Query Frame = 2
Query:  164 MQGIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDNKPVNLGLWDTAGQEDYDRLRPLSYPQTDVFLICFSLINSSSYENVRAKWYPEITHHCPNTPIILVGTKLDLRENHMNGEAGKDRRNTPISYPQGLVLAKEIGAVKYLECSALTQKGLKSVFDEAIRAVLCPKP--PRKKTCKFL 733
            MQ IKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVD KPVNLGLWDTAGQEDYDRLRPLSYPQTDVFLICFSL++ +S+ENVRAKWYPE+ HHCPNTPIILVGTKLDLR++    E  K+R+ TPI+YPQGL +AKEIGAVKYLECSALTQ+ LK+VFDEAIRAVLCP P   RK+ C  L
Sbjct:    1 MQAIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDGKPVNLGLWDTAGQEDYDRLRPLSYPQTDVFLICFSLVSPASFENVRAKWYPEVRHHCPNTPIILVGTKLDLRDDQDTIEKLKERKLTPITYPQGLAMAKEIGAVKYLECSALTQRDLKTVFDEAIRAVLCPPPVKSRKRKCTLL 192          
BLAST of Rac-1 vs. Ensembl Cavefish
Match: rac1a (ras-related C3 botulinum toxin substrate 1 [Source:NCBI gene;Acc:103034053])

HSP 1 Score: 332.413 bits (851), Expect = 2.520e-112
Identity = 158/192 (82.29%), Postives = 173/192 (90.10%), Query Frame = 2
Query:  164 MQGIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDNKPVNLGLWDTAGQEDYDRLRPLSYPQTDVFLICFSLINSSSYENVRAKWYPEITHHCPNTPIILVGTKLDLRENHMNGEAGKDRRNTPISYPQGLVLAKEIGAVKYLECSALTQKGLKSVFDEAIRAVLCPKP--PRKKTCKFL 733
            MQ IKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVD KPVNLGLWDTAGQEDYDRLRPLSYPQTDVFLICFSL++ +S+ENVRAKWYPE+ HHCPNTPIILVGTKLDLR++    E  K+++ TPI+YPQGL +AKEIGAVKYLECSALTQ+GLK+VFDEAIRAVLCP P   RK+ C  L
Sbjct:    1 MQAIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDGKPVNLGLWDTAGQEDYDRLRPLSYPQTDVFLICFSLVSPASFENVRAKWYPEVRHHCPNTPIILVGTKLDLRDDKDTIEKLKEKKLTPITYPQGLAMAKEIGAVKYLECSALTQRGLKTVFDEAIRAVLCPPPVKKRKRKCLLL 192          
BLAST of Rac-1 vs. Ensembl Cavefish
Match: rac3b (ras-related C3 botulinum toxin substrate 3-like [Source:NCBI gene;Acc:111192386])

HSP 1 Score: 329.331 bits (843), Expect = 3.558e-111
Identity = 153/185 (82.70%), Postives = 171/185 (92.43%), Query Frame = 2
Query:  164 MQGIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDNKPVNLGLWDTAGQEDYDRLRPLSYPQTDVFLICFSLINSSSYENVRAKWYPEITHHCPNTPIILVGTKLDLRENHMNGEAGKDRRNTPISYPQGLVLAKEIGAVKYLECSALTQKGLKSVFDEAIRAVLCPKPPRKK 718
            MQ IKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVD KPVNLGLWDTAGQEDYDRLRPLSYPQTDVFLICFSL++ +S+ENVRAKWYPE+ HHCPNTPIILVGTKLDLR++    E  +D++ +PI+YPQGL +A+EIGAVKYLECSALTQ+GLK+VFDEAIRAVLCP P +K+
Sbjct:    1 MQAIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDGKPVNLGLWDTAGQEDYDRLRPLSYPQTDVFLICFSLVSPASFENVRAKWYPEVRHHCPNTPIILVGTKLDLRDDKDTIERLRDKKLSPITYPQGLAMAREIGAVKYLECSALTQRGLKTVFDEAIRAVLCPPPVKKR 185          
BLAST of Rac-1 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000009835.1 (pep scaffold:Pmarinus_7.0:GL479385:19931:31465:1 gene:ENSPMAG00000008880.1 transcript:ENSPMAT00000009835.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 322.013 bits (824), Expect = 4.631e-109
Identity = 150/178 (84.27%), Postives = 165/178 (92.70%), Query Frame = 2
Query:  164 MQGIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDNKPVNLGLWDTAGQEDYDRLRPLSYPQTDVFLICFSLINSSSYENVRAKWYPEITHHCPNTPIILVGTKLDLRENHMNGEAGKDRRNTPISYPQGLVLAKEIGAVKYLECSALTQKGLKSVFDEAIRAVLC 697
            MQ IKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVD KPVNLGLWDTAGQEDYDRLRPLSYPQTDVFLICFSL++ +S+ENVRAKWYPE+ HHCPNTPIILVGTKLDLR++    E  ++++  PI+YPQGL +AKEIGAVKYLECSALTQ+GLK+VFDEAIRAVLC
Sbjct:    1 MQAIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDGKPVNLGLWDTAGQEDYDRLRPLSYPQTDVFLICFSLVSPASFENVRAKWYPEVRHHCPNTPIILVGTKLDLRDDKDTVEKLREKKLAPITYPQGLAMAKEIGAVKYLECSALTQRGLKTVFDEAIRAVLC 178          
BLAST of Rac-1 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000007368.1 (pep scaffold:Pmarinus_7.0:GL476419:214196:224439:-1 gene:ENSPMAG00000006646.1 transcript:ENSPMAT00000007368.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 287.345 bits (734), Expect = 1.787e-95
Identity = 133/193 (68.91%), Postives = 160/193 (82.90%), Query Frame = 2
Query:  164 MQGIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDNKPVNLGLWDTAGQEDYDRLRPLSYPQTDVFLICFSLINSSSYENVRAKWYPEITHHCPNTPIILVGTKLDLRENHMNGEAGKDRRNTPISYPQGLVLAKEIGAVKYLECSALTQKGLKSVFDEAIRAVLCPKPP---RKKTCKFL 733
            MQ IKCVVVGDGAVGKTC+LIS++ N FPGEYIPTVFDNY+ N+MVD K VNLGLWDTAGQEDYDRLRPLSYPQTD+FLICFS+++ SSY+NVR KW+ E+ HHCP TPIILVGTK D RE+    +  +++   P++  QGL LAKEIGA+KYLECSALTQ+GLK+VFDE +RAV+ P+P    +KK+C  L
Sbjct:    1 MQAIKCVVVGDGAVGKTCMLISFSNNTFPGEYIPTVFDNYAVNLMVDGKYVNLGLWDTAGQEDYDRLRPLSYPQTDIFLICFSVVSPSSYDNVRVKWFKEVRHHCPETPIILVGTKQDQREDKDILKHLEEKSMQPVTNAQGLSLAKEIGAIKYLECSALTQRGLKNVFDETVRAVISPEPKIERKKKSCALL 193          
BLAST of Rac-1 vs. Ensembl Sea Lamprey
Match: rhoj (ras homolog family member J [Source:ZFIN;Acc:ZDB-GENE-040724-272])

HSP 1 Score: 224.557 bits (571), Expect = 7.998e-71
Identity = 106/188 (56.38%), Postives = 140/188 (74.47%), Query Frame = 2
Query:  173 IKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDNKPVNLGLWDTAGQEDYDRLRPLSYPQTDVFLICFSLINSSSYENVRAKWYPEITHHCPNTPIILVGTKLDLRENHMNGEAGKDRRNTPISYPQGLVLAKEIGAVKYLECSALTQKGLKSVFDEAIRAVL----CPKPPRKKTC 724
            +KCVVVGDGAVGKTCL++SY  +AFP +Y+PTVFD+Y+ NV V      LGL+DTAGQEDY +LRPLSYP TD+F+ICFS++N +SY NV+ +W PE+   CP+ P +LVGT++DLR+        K+ +  P+++ QG+ LAK+IGA  YLECSALTQKGLK+VFDEAI  +L    C +  R + C
Sbjct:   21 LKCVVVGDGAVGKTCLIMSYANDAFPEQYVPTVFDHYAVNVKVGGSCYLLGLYDTAGQEDYHQLRPLSYPNTDMFMICFSVVNPASYHNVKEEWVPELRACCPDVPYLLVGTQIDLRDATKTLMRLKELKEKPMTHQQGVKLAKQIGAHCYLECSALTQKGLKAVFDEAILTILQRKKCKRSTRCRCC 208          
BLAST of Rac-1 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000004439.1 (pep scaffold:Pmarinus_7.0:GL476335:1598569:1600956:1 gene:ENSPMAG00000004041.1 transcript:ENSPMAT00000004439.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 204.142 bits (518), Expect = 3.279e-63
Identity = 100/188 (53.19%), Postives = 125/188 (66.49%), Query Frame = 2
Query:  176 KCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDNKPVNLGLWDTAGQEDYDRLRPLSYPQTDVFLICFSLINSSSYENVRAKWYPEITHHCPNTPIILVGTKLDLRENHMNGEAGKDRRNTPISYPQGLVLAKEIGAVKYLECSALTQKGLKSVFDEAIRAVLCPKPPRKKT--CKFL 733
            K V+VGDGA GKTCLLI ++ + FP  Y+PTVF+NY A++ VD K V L LWDTAGQEDYDRLRPLSYP TDV L+CFS+ +  S EN+  KW PE+ H CPN PIILVG K DLR +          +  P+   +G  +A  I A  Y+ECSA T+ G++ VF+ A RA L  +  RKKT  C+ L
Sbjct:    7 KLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYVADIEVDGKQVELALWDTAGQEDYDRLRPLSYPDTDVILMCFSIDSPDSLENIPEKWTPEVKHFCPNVPIILVGNKKDLRNDDNTKRELAKMKQEPVRVEEGRDMANRINAFGYMECSAKTKDGVREVFEMATRAALQVR-KRKKTGGCRLL 193          
BLAST of Rac-1 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000001838.1 (pep scaffold:Pmarinus_7.0:GL478831:173097:182385:-1 gene:ENSPMAG00000001664.1 transcript:ENSPMAT00000001838.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 202.986 bits (515), Expect = 1.001e-62
Identity = 94/173 (54.34%), Postives = 117/173 (67.63%), Query Frame = 2
Query:  176 KCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDNKPVNLGLWDTAGQEDYDRLRPLSYPQTDVFLICFSLINSSSYENVRAKWYPEITHHCPNTPIILVGTKLDLRENHMNGEAGKDRRNTPISYPQGLVLAKEIGAVKYLECSALTQKGLKSVFDEAIRAVL 694
            K V+VGDGA GKTCLLI ++ + FP  Y+PTVF+NY A++ VD K V L LWDTAGQEDYDRLRPLSYP TDV L+CFS+ +  S EN+  KW PE+ H CPN PIILVG K DLR +          +  P+   +G  +A  I A  Y+ECSA T+ G++ VF+ A RA L
Sbjct:    7 KLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYVADIEVDGKQVELALWDTAGQEDYDRLRPLSYPDTDVILMCFSIDSPDSLENIPEKWTPEVKHFCPNVPIILVGNKKDLRNDESTRRELAKMKQEPVKSEEGRDMANRINAFGYMECSAKTKDGVREVFEMATRAAL 179          
BLAST of Rac-1 vs. Ensembl Yeast
Match: CDC42 (Small rho-like GTPase; essential for establishment and maintenance of cell polarity; plays a role late in cell fusion via activation of key cell fusion regulator Fus2p; mutants have defects in the organization of actin and septins; human homolog CDC42 can complement yeast cdc42 mutant [Source:SGD;Acc:S000004219])

HSP 1 Score: 257.684 bits (657), Expect = 4.057e-84
Identity = 121/191 (63.35%), Postives = 152/191 (79.58%), Query Frame = 2
Query:  164 MQGIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDNKPVNLGLWDTAGQEDYDRLRPLSYPQTDVFLICFSLINSSSYENVRAKWYPEITHHCPNTPIILVGTKLDLRENHMNGEAGKDRRNTPISYPQGLVLAKEIGAVKYLECSALTQKGLKSVFDEAIRAVLCPKPPRK-KTCKFL 733
            MQ +KCVVVGDGAVGKTCLLISYTTN FP +Y+PTVFDNY+  VM+ ++P  LGL+DTAGQEDYDRLRPLSYP TDVFL+CFS+I+  S+ENV+ KW+PE+ HHCP  P ++VGT++DLR++ +  E  + +R  PI+  QG  LA+E+ AVKY+ECSALTQ+GLK+VFDEAI A L P   +K K C  L
Sbjct:    1 MQTLKCVVVGDGAVGKTCLLISYTTNQFPADYVPTVFDNYAVTVMIGDEPYTLGLFDTAGQEDYDRLRPLSYPSTDVFLVCFSVISPPSFENVKEKWFPEVHHHCPGVPCLVVGTQIDLRDDKVIIEKLQRQRLRPITSEQGSRLARELKAVKYVECSALTQRGLKNVFDEAIVAALEPPVIKKSKKCAIL 191          
BLAST of Rac-1 vs. Ensembl Yeast
Match: RHO1 (GTP-binding protein of the rho subfamily of Ras-like proteins; involved in establishment of cell polarity; regulates protein kinase C (Pkc1p) and the cell wall synthesizing enzyme 1,3-beta-glucan synthase (Fks1p and Gsc2p) [Source:SGD;Acc:S000006369])

HSP 1 Score: 193.356 bits (490), Expect = 3.943e-59
Identity = 94/176 (53.41%), Postives = 117/176 (66.48%), Query Frame = 2
Query:  176 KCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDNKPVNLGLWDTAGQEDYDRLRPLSYPQTDVFLICFSLINSSSYENVRAKWYPEITHHCPNTPIILVGTKLDLRENHMNGEAGKDRRNTPISYPQGLVLAKEIGAVKYLECSALTQKGLKSVFDEAIRAVLCPK 703
            K V+VGDGA GKTCLLI ++   FP  Y+PTVF+NY A+V VD + V L LWDTAGQEDYDRLRPLSYP ++V LICFS+    S ENV+ KW  E+ H C   PIILVG K+DLR +    E  +     P++  +G  +A +IGA  Y ECSA T  G++ VF+ A RA L  K
Sbjct:   12 KLVIVGDGACGKTCLLIVFSKGQFPEVYVPTVFENYVADVEVDGRRVELALWDTAGQEDYDRLRPLSYPDSNVVLICFSIDLPDSLENVQEKWIAEVLHFCQGVPIILVGCKVDLRNDPQTIEQLRQEGQQPVTSQEGQSVADQIGATGYYECSAKTGYGVREVFEAATRASLMGK 187          
BLAST of Rac-1 vs. Ensembl Yeast
Match: RHO5 (Non-essential small GTPase of the Rho/Rac family of Ras-like proteins; RAC1 ortholog; regulated by phosphorylation and ubiquitination; likely involved in protein kinase C (Pkc1p)-dependent signal transduction pathway that controls cell integrity [Source:SGD;Acc:S000005124])

HSP 1 Score: 187.193 bits (474), Expect = 2.976e-55
Identity = 104/247 (42.11%), Postives = 140/247 (56.68%), Query Frame = 2
Query:  164 MQGIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMV------------------------------DNKPVNLGLWDTAGQEDYDRLRPLSYPQTDVFLICFSLINSSSYENVRAKWYPEI--THHCPNT---------PIILVGTKLDLRENHMNGEAGKDRRNTPISYPQGLVLAKEIGAVKYLECSALTQKGLKSVFDEAIR-AVLCPKPPRKKTCKFL*RMHNFIDEITNKFT 778
            M+ IKCV++GDGAVGKT LLISYTTN+FP +Y+PTVFDNYS  + +                              D K   + LWDTAGQEDYDRLRPL YPQTD+FLICFS+   +S+ NV  KW PE+  T +   T         PI+LVGTK DLR++    +  ++  +  +S  +   L +  G + Y ECSA TQ G++ VF++A+R A+  P+ P +K+       H   DE+T   T
Sbjct:    1 MRSIKCVIIGDGAVGKTSLLISYTTNSFPTDYVPTVFDNYSTTIAIPNGTASSPLELDNGNDKRGSLSSASSSPSTDRKLYKINLWDTAGQEDYDRLRPLCYPQTDIFLICFSVSEHASFANVTEKWLPELKQTSNIEGTSLYTKLGKYPILLVGTKSDLRDDPATQKKLQEANSDYVSQEEIDELVQRCGFMGYTECSAATQAGVREVFEQAVRYAIYEPESPNQKSAN-----HTLTDELTTATT 242          
BLAST of Rac-1 vs. Ensembl Yeast
Match: RHO3 (Non-essential small GTPase of the Rho/Rac family of Ras-like proteins; involved in the establishment of cell polarity; GTPase activity positively regulated by the GTPase activating protein (GAP) Rgd1p [Source:SGD;Acc:S000001380])

HSP 1 Score: 171.014 bits (432), Expect = 2.473e-50
Identity = 88/198 (44.44%), Postives = 117/198 (59.09%), Query Frame = 2
Query:  176 KCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDNKPVNLGLWDTAGQEDYDRLRPLSYPQTDVFLICFSLINSSSYENVRAKWYPEITHHCPNTPIILVGTKLDLR----------------ENHMNGEAGKDRRNTP-----ISYPQGLVLAKEIGAVKYLECSALTQKGLKSVFDEAIRAVLCPKP 706
            K V++GDGA GKT LL  +T   FP  Y PTVF+NY  ++ VD+K + L LWDTAGQE++DRLR LSY  T   ++CFS+ +  S ENV+ KW  EIT HC    ++LV  K DLR                +N ++ + G +  +T      ISY +GL +AK+IGA++YLECSA   KG+   F EA R  L   P
Sbjct:   18 KIVILGDGACGKTSLLNVFTRGYFPEVYEPTVFENYIHDIFVDSKHITLSLWDTAGQEEFDRLRSLSYSDTQCIMLCFSIDSRDSLENVQNKWVGEITDHCEGVKLVLVALKCDLRNNENESNAITPNNIQQDNSVSNDNGNNINSTSNGKNLISYEEGLAMAKKIGALRYLECSAKLNKGVNEAFTEAARVALTAGP 215          
BLAST of Rac-1 vs. Ensembl Yeast
Match: RHO4 (Non-essential small GTPase; member of the Rho/Rac subfamily of Ras-like proteins; likely to be involved in the establishment of cell polarity; has long N-terminal extension that plays an important role in Rho4p function and is shared with Rho4 homologs in other yeasts and filamentous fungi [Source:SGD;Acc:S000001763])

HSP 1 Score: 169.088 bits (427), Expect = 5.944e-49
Identity = 83/175 (47.43%), Postives = 113/175 (64.57%), Query Frame = 2
Query:  173 IKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDN-KPVNLGLWDTAGQEDYDRLRPLSYPQTDVFLICFSLINSSSYENVRAKWYPEITHHCPNTPIILVGTKLDLRENHMNGEAGKDRRNTPISYPQGLVLAKEIGAVKYLECSALTQKGLKSVFDEAIRAVL 694
            +K VVVGDGAVGKTCLLISY    FP +YIPT+F+NY  N+   N + + L LWDTAGQE+Y RLRPLSY   DV ++C+S+ + +S +NV   W+PE+ H CP+TPI+LVG K DL E         D  +  +       LAK +GA  +++CSA  ++ +  VF+ AI  +L
Sbjct:   73 LKIVVVGDGAVGKTCLLISYVQGTFPTDYIPTIFENYVTNIEGPNGQIIELALWDTAGQEEYSRLRPLSYTNADVLMVCYSVGSKTSLKNVEDLWFPEVKHFCPSTPIMLVGLKSDLYE--------ADNLSDLVEPSSAESLAKRLGAFAHIQCSARLKENIDEVFETAIHTLL 239          
BLAST of Rac-1 vs. Ensembl Nematostella
Match: EDO38536 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SCK6])

HSP 1 Score: 329.717 bits (844), Expect = 9.326e-112
Identity = 158/194 (81.44%), Postives = 172/194 (88.66%), Query Frame = 2
Query:  164 MQGIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDNKPVNLGLWDTAGQEDYDRLRPLSYPQTDVFLICFSLINSSSYENVRAKWYPEITHHCPNTPIILVGTKLDLRENHMNGEAGKDRRNTPISYPQGLVLAKEIGAVKYLECSALTQKGLKSVFDEAIRAVLCP----KPPRKKTCKFL 733
            MQ IKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVD KP+NLGLWDTAGQEDYDRLRPLSYPQTDVFLICFSLI+ +SYENVRAKWYPE++HHCPNTPI+LVGTKLDLR++    +  K+++  PI Y QGL +AKEIGAVKYLECSALTQKGLK+VFDEAIRAVLCP    K PR K CK L
Sbjct:    1 MQAIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDGKPINLGLWDTAGQEDYDRLRPLSYPQTDVFLICFSLISPASYENVRAKWYPEVSHHCPNTPIVLVGTKLDLRDDKETIDKLKEKKLGPIGYTQGLQMAKEIGAVKYLECSALTQKGLKTVFDEAIRAVLCPTKPAKKPRNKGCKLL 194          
BLAST of Rac-1 vs. Ensembl Nematostella
Match: EDO35019 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SMN7])

HSP 1 Score: 301.597 bits (771), Expect = 7.767e-101
Identity = 141/177 (79.66%), Postives = 158/177 (89.27%), Query Frame = 2
Query:  164 MQGIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDNKPVNLGLWDTAGQEDYDRLRPLSYPQTDVFLICFSLINSSSYENVRAKWYPEITHHCPNTPIILVGTKLDLRENHMNGEAGKDRRNTPISYPQGLVLAKEIGAVKYLECSALTQKGLKSVFDEAIRAVL 694
            MQ IKCVVVGDGAVGKTC+LISYTTNAFPGEYIPTVFDNYSANVMVD +P+NLGLWDTAGQEDYDRLRPLSYPQTDVFLICFS+I+ +S+ENVRAKWYPE++HHCP TPIILVGTK DLRE+    E  K+++  P+S   GL +AKEI A KYLECSALTQKGLK+VFD+AIRAVL
Sbjct:    1 MQAIKCVVVGDGAVGKTCMLISYTTNAFPGEYIPTVFDNYSANVMVDGRPINLGLWDTAGQEDYDRLRPLSYPQTDVFLICFSVISPASFENVRAKWYPEVSHHCPGTPIILVGTKTDLREDKEMIEKLKEKKLNPLSTSHGLQMAKEIKAAKYLECSALTQKGLKTVFDDAIRAVL 177          
BLAST of Rac-1 vs. Ensembl Nematostella
Match: EDO37472 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SFJ1])

HSP 1 Score: 270.396 bits (690), Expect = 1.220e-88
Identity = 127/191 (66.49%), Postives = 152/191 (79.58%), Query Frame = 2
Query:  164 MQGIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDNKPVNLGLWDTAGQEDYDRLRPLSYPQTDVFLICFSLINSSSYENVRAKWYPEITHHCPNTPIILVGTKLDLRENHMNGEAGKDRRNTPISYPQGLVLAKEIGAVKYLECSALTQKGLKSVFDEAIRAVL-CPKPPRKKTCKFL 733
            MQ IKCVVVGDGAVGKTCLLISYTTN FP EY+PTVFDNY+  VM+  +P  LGL+DTAGQEDYDRLRPLSYPQTDVFL+CFS+++ SS+ENV+ KW PEITHHCP TP +LVGT++DLR++    E     +  PI+      LA+E+ AVKY+ECSALTQKGLK+VFDEAI A L  P+P +KK C+ L
Sbjct:    1 MQTIKCVVVGDGAVGKTCLLISYTTNKFPSEYVPTVFDNYAVTVMIGGEPYTLGLFDTAGQEDYDRLRPLSYPQTDVFLVCFSVVSPSSFENVKEKWVPEITHHCPKTPFLLVGTQVDLRDDQGTIEKLSKNKQKPIAVEAAEKLARELRAVKYVECSALTQKGLKNVFDEAILAALEPPEPQKKKKCRLL 191          
BLAST of Rac-1 vs. Ensembl Nematostella
Match: EDO39465 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S9Y5])

HSP 1 Score: 205.682 bits (522), Expect = 1.377e-63
Identity = 95/173 (54.91%), Postives = 119/173 (68.79%), Query Frame = 2
Query:  176 KCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDNKPVNLGLWDTAGQEDYDRLRPLSYPQTDVFLICFSLINSSSYENVRAKWYPEITHHCPNTPIILVGTKLDLRENHMNGEAGKDRRNTPISYPQGLVLAKEIGAVKYLECSALTQKGLKSVFDEAIRAVL 694
            K V+VGDGA GKTCLLI ++ + FP  Y+PTVF+NY A++ VD K V L LWDTAGQEDYDRLRPLSYP TDV L+CFS+ +  S EN+  KW PE+ H CPN PIILVG K DLR +       +  +  P+   +G  +A +I A  YLECSA T+ G++ VF+ A RA L
Sbjct:    7 KLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYVADIEVDGKQVELALWDTAGQEDYDRLRPLSYPDTDVILMCFSIDSPDSLENIPEKWTPEVKHFCPNVPIILVGNKKDLRMDENTKRELQKMKQEPVKIEEGRAMADKISAYAYLECSAKTKDGVREVFETATRAAL 179          
BLAST of Rac-1 vs. Ensembl Nematostella
Match: EDO36553 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SI94])

HSP 1 Score: 201.83 bits (512), Expect = 1.087e-57
Identity = 105/173 (60.69%), Postives = 129/173 (74.57%), Query Frame = 2
Query:  167 QGIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDNKPVNLGLWDTAGQEDYDRLRPLSYPQTDVFLICFSLINSSSYENVRAKWYPEITHHCPNTPIILVGTKLDLRENHMNGEAGKDRRNTPISYPQGLVLAKEIGAVKYLECSALTQKGLKSVFDEAIR 685
            Q +K VVVGDG VGK+  LI+ TTNAFPGEYIPTVFDNYS+N+M+D K  N+GLWDTAGQEDYDRLRPLSYP TDVFL+CF + + +S+EN+ +KW PE+ HH P TP ILVG K DLR       A ++    PI+Y +G  LAK +G ++YLE S+LTQ G+K V   AIR
Sbjct:    4 QNVKLVVVGDGGVGKSAFLITATTNAFPGEYIPTVFDNYSSNIMLDGKAYNVGLWDTAGQEDYDRLRPLSYPMTDVFLVCFDIGSRTSFENIESKWLPELNHHMPETPKILVGNKRDLR------SAQQNTSRDPITYEEGKALAKRLG-MQYLENSSLTQDGVKDVMSAAIR 169          
BLAST of Rac-1 vs. Ensembl Medaka
Match: ENSORLT00000041989.1 (Rac family small GTPase 2 [Source:NCBI gene;Acc:101163549])

HSP 1 Score: 328.946 bits (842), Expect = 5.169e-111
Identity = 154/185 (83.24%), Postives = 169/185 (91.35%), Query Frame = 2
Query:  164 MQGIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDNKPVNLGLWDTAGQEDYDRLRPLSYPQTDVFLICFSLINSSSYENVRAKWYPEITHHCPNTPIILVGTKLDLRENHMNGEAGKDRRNTPISYPQGLVLAKEIGAVKYLECSALTQKGLKSVFDEAIRAVLCPKPPRKK 718
            MQ IKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVD+KPVNLGLWDTAGQEDYDRLRPLSYPQTDVFLICFSL++ +SYENVRAKWYPE+ HHCP+TPIILVGTKLDLR+     E  K+++  PI+YPQGL LAKEI AVKYLECSALTQ+GLK+VFDEAIRAVLCP+P + K
Sbjct:    1 MQAIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDSKPVNLGLWDTAGQEDYDRLRPLSYPQTDVFLICFSLVSPASYENVRAKWYPEVRHHCPSTPIILVGTKLDLRDEKDTIEKLKEKKLAPITYPQGLALAKEIDAVKYLECSALTQRGLKTVFDEAIRAVLCPQPAKVK 185          
BLAST of Rac-1 vs. Ensembl Medaka
Match: ENSORLT00000038381.1 (ras-related C3 botulinum toxin substrate 1 [Source:NCBI gene;Acc:101175028])

HSP 1 Score: 327.02 bits (837), Expect = 2.602e-110
Identity = 156/192 (81.25%), Postives = 171/192 (89.06%), Query Frame = 2
Query:  164 MQGIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDNKPVNLGLWDTAGQEDYDRLRPLSYPQTDVFLICFSLINSSSYENVRAKWYPEITHHCPNTPIILVGTKLDLRENHMNGEAGKDRRNTPISYPQGLVLAKEIGAVKYLECSALTQKGLKSVFDEAIRAVLCPKPPRKK--TCKFL 733
            MQ IKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVD KPVNLGLWDTAGQEDYDRLRPLSYPQTDVFLICFSL++ +S+ENVRAKWYPE+ HHCP TPIILVGTKLDLR++    E  K+++ +PI YPQGL +AKEI AVKYLECSALTQ+GLK+VFDEAIRAVLCP P RKK   C+ L
Sbjct:    1 MQAIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDGKPVNLGLWDTAGQEDYDRLRPLSYPQTDVFLICFSLVSPASFENVRAKWYPEVRHHCPVTPIILVGTKLDLRDDKDTIEKLKEKKLSPIIYPQGLAMAKEISAVKYLECSALTQRGLKTVFDEAIRAVLCPPPDRKKKRKCRIL 192          
BLAST of Rac-1 vs. Ensembl Medaka
Match: RAC1 (ras-related C3 botulinum toxin substrate 1 [Source:NCBI gene;Acc:101159016])

HSP 1 Score: 321.242 bits (822), Expect = 4.591e-108
Identity = 149/177 (84.18%), Postives = 165/177 (93.22%), Query Frame = 2
Query:  164 MQGIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDNKPVNLGLWDTAGQEDYDRLRPLSYPQTDVFLICFSLINSSSYENVRAKWYPEITHHCPNTPIILVGTKLDLRENHMNGEAGKDRRNTPISYPQGLVLAKEIGAVKYLECSALTQKGLKSVFDEAIRAVL 694
            MQ IKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVD KPVNLGLWDTAGQEDYDRLRPLSYPQTDVFLICFSL++ +S+ENVRAKWYPE+ HHCPNTPIILVGTKLDLR++    E  K+++ +PI+YPQGL +AKEIG+VKYLECSALTQ+GLK+VFDEAIRAVL
Sbjct:    1 MQAIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDGKPVNLGLWDTAGQEDYDRLRPLSYPQTDVFLICFSLVSPASFENVRAKWYPEVRHHCPNTPIILVGTKLDLRDDKETTEKLKEKKLSPITYPQGLAMAKEIGSVKYLECSALTQRGLKTVFDEAIRAVL 177          
BLAST of Rac-1 vs. Ensembl Medaka
Match: RAC1 (ras-related C3 botulinum toxin substrate 1 [Source:NCBI gene;Acc:101159016])

HSP 1 Score: 321.242 bits (822), Expect = 4.591e-108
Identity = 149/177 (84.18%), Postives = 165/177 (93.22%), Query Frame = 2
Query:  164 MQGIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDNKPVNLGLWDTAGQEDYDRLRPLSYPQTDVFLICFSLINSSSYENVRAKWYPEITHHCPNTPIILVGTKLDLRENHMNGEAGKDRRNTPISYPQGLVLAKEIGAVKYLECSALTQKGLKSVFDEAIRAVL 694
            MQ IKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVD KPVNLGLWDTAGQEDYDRLRPLSYPQTDVFLICFSL++ +S+ENVRAKWYPE+ HHCPNTPIILVGTKLDLR++    E  K+++ +PI+YPQGL +AKEIG+VKYLECSALTQ+GLK+VFDEAIRAVL
Sbjct:    1 MQAIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDGKPVNLGLWDTAGQEDYDRLRPLSYPQTDVFLICFSLVSPASFENVRAKWYPEVRHHCPNTPIILVGTKLDLRDDKETTEKLKEKKLSPITYPQGLAMAKEIGSVKYLECSALTQRGLKTVFDEAIRAVL 177          
BLAST of Rac-1 vs. Ensembl Medaka
Match: rac3b (ras-related C3 botulinum toxin substrate 3 [Source:NCBI gene;Acc:105354522])

HSP 1 Score: 306.22 bits (783), Expect = 4.389e-102
Identity = 142/173 (82.08%), Postives = 160/173 (92.49%), Query Frame = 2
Query:  200 AVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDNKPVNLGLWDTAGQEDYDRLRPLSYPQTDVFLICFSLINSSSYENVRAKWYPEITHHCPNTPIILVGTKLDLRENHMNGEAGKDRRNTPISYPQGLVLAKEIGAVKYLECSALTQKGLKSVFDEAIRAVLCPKPPRKK 718
            AVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVD KPVNLGLWDTAGQEDYDRLRPLSYPQTDVFLICFSL++ +S+ENVRAKWYPE+ HHCPNTPIILVGTKLDLR++    E  +D++ +PI+YPQGL +A+EIGAVKYLECSALTQ+GLK+VFDEAIRAVLCP P +K+
Sbjct:   18 AVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDGKPVNLGLWDTAGQEDYDRLRPLSYPQTDVFLICFSLVSPASFENVRAKWYPEVRHHCPNTPIILVGTKLDLRDDKDTIERLRDKKLSPITYPQGLAMAREIGAVKYLECSALTQRGLKTVFDEAIRAVLCPPPVKKR 190          
BLAST of Rac-1 vs. Planmine SMEST
Match: SMESG000024961.1 (SMESG000024961.1)

HSP 1 Score: 397.512 bits (1020), Expect = 4.393e-138
Identity = 190/190 (100.00%), Postives = 190/190 (100.00%), Query Frame = 2
Query:  164 MQGIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDNKPVNLGLWDTAGQEDYDRLRPLSYPQTDVFLICFSLINSSSYENVRAKWYPEITHHCPNTPIILVGTKLDLRENHMNGEAGKDRRNTPISYPQGLVLAKEIGAVKYLECSALTQKGLKSVFDEAIRAVLCPKPPRKKTCKFL 733
            MQGIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDNKPVNLGLWDTAGQEDYDRLRPLSYPQTDVFLICFSLINSSSYENVRAKWYPEITHHCPNTPIILVGTKLDLRENHMNGEAGKDRRNTPISYPQGLVLAKEIGAVKYLECSALTQKGLKSVFDEAIRAVLCPKPPRKKTCKFL
Sbjct:    1 MQGIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDNKPVNLGLWDTAGQEDYDRLRPLSYPQTDVFLICFSLINSSSYENVRAKWYPEITHHCPNTPIILVGTKLDLRENHMNGEAGKDRRNTPISYPQGLVLAKEIGAVKYLECSALTQKGLKSVFDEAIRAVLCPKPPRKKTCKFL 190          
BLAST of Rac-1 vs. Planmine SMEST
Match: SMESG000024968.1 (SMESG000024968.1)

HSP 1 Score: 317.775 bits (813), Expect = 6.312e-107
Identity = 154/191 (80.63%), Postives = 166/191 (86.91%), Query Frame = 2
Query:  164 MQGIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDNKPVNLGLWDTAGQEDYDRLRPLSYPQTDVFLICFSLINSSSYENVRAKWYPEITHHCPNTPIILVGTKLDLRENHMNGEAGKDRRNTPISYPQGLVLAKEIGAVKYLECSALTQKGLKSVFDEAIRAVLCPKPPR-KKTCKFL 733
            MQGIKCVVVGDGAVGKTCLLISYTT+AFPGEYIPTVFDNYSAN+MVDNKPVNLGLWDTAGQEDYDRLRPLSYPQTDVF+ICFSL+N SSYENVRAKWYPE+ +HCPNTPIILVGTKLDLR+     + G       ISYPQGL+L KEIGA KYLECSALTQ GLK+VFDE+IR VLCPK  + KK C  L
Sbjct:    1 MQGIKCVVVGDGAVGKTCLLISYTTSAFPGEYIPTVFDNYSANIMVDNKPVNLGLWDTAGQEDYDRLRPLSYPQTDVFIICFSLVNPSSYENVRAKWYPEVNNHCPNTPIILVGTKLDLRDESQTNKTGGH-----ISYPQGLILMKEIGAKKYLECSALTQTGLKTVFDESIRVVLCPKQKQNKKRCSIL 186          
BLAST of Rac-1 vs. Planmine SMEST
Match: SMESG000005010.1 (SMESG000005010.1)

HSP 1 Score: 268.855 bits (686), Expect = 1.091e-87
Identity = 129/194 (66.49%), Postives = 155/194 (79.90%), Query Frame = 2
Query:  164 MQGIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDNKPVNLGLWDTAGQEDYDRLRPLSYPQTDVFLICFSLINSSSYENVRAKWYPEITHHCPNTPIILVGTKLDLRENHMNGEAGKDR-RNTPISYPQGLVLAKEIGAVKYLECSALTQKGLKSVFDEAIRAVLC-PKP--PRKKTCKFL 733
            M+ IKCVVVGDGAVGKTC+LISYTT+AFP  ++PTVFDN SANVM++  P+NLGLWDTAGQE+YDRLRPLSYP+TDVFLICFSL+N  S+ NV+ KWY E++H    TPIILVGTKLDLRE     E  K++ R++P++Y QGL L +EIGAVKY+ECSA TQ  L+ VF+EAIR V+  PKP  PR K C  L
Sbjct:    1 MRSIKCVVVGDGAVGKTCILISYTTDAFPTTHVPTVFDNMSANVMIEGTPINLGLWDTAGQEEYDRLRPLSYPETDVFLICFSLVNKDSFANVKEKWYKEVSHFSKETPIILVGTKLDLREERALNENDKNQIRSSPVTYQQGLALCQEIGAVKYIECSARTQVNLRQVFEEAIRVVINKPKPSNPRFKFCSLL 194          
BLAST of Rac-1 vs. Planmine SMEST
Match: SMESG000064161.1 (SMESG000064161.1)

HSP 1 Score: 249.595 bits (636), Expect = 3.093e-80
Identity = 119/195 (61.03%), Postives = 148/195 (75.90%), Query Frame = 2
Query:  161 IMQGIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDNKPVNLGLWDTAGQEDYDRLRPLSYPQTDVFLICFSLINSSSYENVRAKWYPEITHHCPNTPIILVGTKLDLRENHMNGEAGKDRRNTPISYPQGLVLAKEIGAVKYLECSALTQKGLKSVFDEAIRAVLCPKPPR----KKTCKFL 733
            ++Q IKCVVVGDGAVGKTCLLISYTTN FP +Y+PTVFDNY+  VM+   P  LGL+DTAGQEDYDRLRPLSYP TDVFL+CFS++N +S+ENV+ KW PEI HHCP  P +LVGT+ D R++ +  +     +   I+  QG  LAK++ AVKY+ECSALTQKGLK+VFDEAI A L  +PP+    K+ C  +
Sbjct:    1 MVQTIKCVVVGDGAVGKTCLLISYTTNKFPKDYVPTVFDNYAVTVMIGGDPYTLGLFDTAGQEDYDRLRPLSYPNTDVFLVCFSVVNPASFENVKDKWVPEIQHHCPKVPFLLVGTQADKRDDTVEQDKLSRNKQKCITEDQGTRLAKDLKAVKYVECSALTQKGLKNVFDEAILAAL--EPPQDSHAKRKCSLI 193          
BLAST of Rac-1 vs. Planmine SMEST
Match: SMESG000005012.1 (SMESG000005012.1)

HSP 1 Score: 247.669 bits (631), Expect = 1.706e-79
Identity = 114/178 (64.04%), Postives = 145/178 (81.46%), Query Frame = 2
Query:  164 MQGIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDNKPVNLGLWDTAGQEDYDRLRPLSYPQTDVFLICFSLINSSSYENVRAKWYPEITHHCPNTPIILVGTKLDLRENHMNGEAGKDR-RNTPISYPQGLVLAKEIGAVKYLECSALTQKGLKSVFDEAIRAVL 694
            M+ IKCVV+GDGAVGKTC+L+S+TT+ F    IPTVFDN SAN+M+D KP+NLGLWDTAGQ+D+D +R +SYPQTDVFLICFSL+N  S+ NV+ KW+ E++H+  NTPIILVGTKLDLR+N    E  K +  ++P++Y QGL L +EIGAVKY+ECSA TQ+ LK VF+EA+R VL
Sbjct:    1 MRSIKCVVIGDGAVGKTCILVSFTTDVFSSSPIPTVFDNMSANMMIDGKPINLGLWDTAGQDDFDGIRVVSYPQTDVFLICFSLVNKVSFVNVKEKWFKEVSHYSENTPIILVGTKLDLRDNKDFDEHDKGQVFSSPVTYQQGLALCQEIGAVKYIECSAKTQENLKMVFEEAVRIVL 178          
The following BLAST results are available for this feature:
BLAST of Rac-1 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5
Match NameE-valueIdentityDescription
RAC14.674e-11282.29Rac family small GTPase 1 [Source:HGNC Symbol;Acc:... [more]
RAC23.479e-11180.73Rac family small GTPase 2 [Source:HGNC Symbol;Acc:... [more]
RAC12.592e-10774.88Rac family small GTPase 1 [Source:HGNC Symbol;Acc:... [more]
RAC31.026e-10682.58Rac family small GTPase 3 [Source:HGNC Symbol;Acc:... [more]
RAC25.209e-10377.08Rac family small GTPase 2 [Source:HGNC Symbol;Acc:... [more]
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BLAST of Rac-1 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 5
Match NameE-valueIdentityDescription
ced-108.855e-10679.79Ras-related protein ced-10 [Source:UniProtKB/Swis... [more]
rac-24.831e-9574.86Ras-related protein rac-2 [Source:UniProtKB/Swiss... [more]
cdc-424.802e-8565.97Cell division control protein 42 homolog [Source:... [more]
mig-21.387e-8463.30Rac-like GTPase [Source:UniProtKB/TrEMBL;Acc:G5EB... [more]
rho-13.324e-6455.49Ras-like GTP-binding protein rhoA [Source:UniProt... [more]
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BLAST of Rac-1 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Rac19.902e-11280.73gene:FBgn0010333 transcript:FBtr0072730[more]
Rac19.902e-11280.73gene:FBgn0010333 transcript:FBtr0331868[more]
Rac21.009e-11079.69gene:FBgn0014011 transcript:FBtr0076867[more]
Rac21.009e-11079.69gene:FBgn0014011 transcript:FBtr0332800[more]
Cdc422.036e-9068.06gene:FBgn0010341 transcript:FBtr0309215[more]
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BLAST of Rac-1 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
rac24.066e-11181.91Rac family small GTPase 2 [Source:ZFIN;Acc:ZDB-GEN... [more]
rac3b4.198e-11182.70Rac family small GTPase 3b [Source:ZFIN;Acc:ZDB-GE... [more]
rac3a5.813e-11182.70Rac family small GTPase 3a [Source:ZFIN;Acc:ZDB-GE... [more]
rac1a5.877e-11185.08Rac family small GTPase 1a [Source:ZFIN;Acc:ZDB-GE... [more]
rac26.204e-11181.25Rac family small GTPase 2 [Source:ZFIN;Acc:ZDB-GEN... [more]
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BLAST of Rac-1 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5
Match NameE-valueIdentityDescription
rac14.237e-11282.29Rac family small GTPase 1 [Source:NCBI gene;Acc:44... [more]
yju22.861e-11182.29YJU2 splicing factor homolog [Source:Xenbase;Acc:X... [more]
nab21.440e-11082.45NGFI-A binding protein 2 (EGR1 binding protein 2) ... [more]
nab22.311e-10479.03NGFI-A binding protein 2 (EGR1 binding protein 2) ... [more]
yju25.775e-10281.67YJU2 splicing factor homolog [Source:Xenbase;Acc:X... [more]
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BLAST of Rac-1 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Rac13.209e-11282.29Rac family small GTPase 1 [Source:MGI Symbol;Acc:M... [more]
Rac22.714e-11080.21Rac family small GTPase 2 [Source:MGI Symbol;Acc:M... [more]
Rac14.470e-10775.12Rac family small GTPase 1 [Source:MGI Symbol;Acc:M... [more]
Rac37.042e-10782.58Rac family small GTPase 3 [Source:MGI Symbol;Acc:M... [more]
Rac33.955e-9881.93Rac family small GTPase 3 [Source:MGI Symbol;Acc:M... [more]
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BLAST of Rac-1 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|Q6RUV5|RAC1_RAT2.245e-11182.29Ras-related C3 botulinum toxin substrate 1 OS=Ratt... [more]
sp|P63001|RAC1_MOUSE2.245e-11182.29Ras-related C3 botulinum toxin substrate 1 OS=Mus ... [more]
sp|P63000|RAC1_HUMAN2.245e-11182.29Ras-related C3 botulinum toxin substrate 1 OS=Homo... [more]
sp|P62999|RAC1_CANLF2.245e-11182.29Ras-related C3 botulinum toxin substrate 1 OS=Cani... [more]
sp|P62998|RAC1_BOVIN2.245e-11182.29Ras-related C3 botulinum toxin substrate 1 OS=Bos ... [more]
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BLAST of Rac-1 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
F1AGC04.662e-116100.00Rac-1 (Fragment) OS=Schmidtea mediterranea OX=7932... [more]
A0A087UI471.775e-11183.33Ras-related C3 botulinum toxin substrate 1 (Fragme... [more]
A0A131XE628.293e-11182.81Putative ras-related c3 botulinum toxin substrate ... [more]
A0A1E1X0F38.293e-11182.81Putative ras-related c3 botulinum toxin substrate ... [more]
A0A023GI748.293e-11182.81Putative ras-related c3 botulinum toxin substrate ... [more]
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BLAST of Rac-1 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
rac1b2.099e-11382.81ras-related C3 botulinum toxin substrate 1-like [S... [more]
rac1b1.880e-11282.29ras-related C3 botulinum toxin substrate 1-like [S... [more]
rac1b1.880e-11282.29ras-related C3 botulinum toxin substrate 1-like [S... [more]
rac1a2.520e-11282.29ras-related C3 botulinum toxin substrate 1 [Source... [more]
rac3b3.558e-11182.70ras-related C3 botulinum toxin substrate 3-like [S... [more]
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BLAST of Rac-1 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 5
Match NameE-valueIdentityDescription
ENSPMAT00000009835.14.631e-10984.27pep scaffold:Pmarinus_7.0:GL479385:19931:31465:1 g... [more]
ENSPMAT00000007368.11.787e-9568.91pep scaffold:Pmarinus_7.0:GL476419:214196:224439:-... [more]
rhoj7.998e-7156.38ras homolog family member J [Source:ZFIN;Acc:ZDB-G... [more]
ENSPMAT00000004439.13.279e-6353.19pep scaffold:Pmarinus_7.0:GL476335:1598569:1600956... [more]
ENSPMAT00000001838.11.001e-6254.34pep scaffold:Pmarinus_7.0:GL478831:173097:182385:-... [more]
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BLAST of Rac-1 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 5
Match NameE-valueIdentityDescription
CDC424.057e-8463.35Small rho-like GTPase; essential for establishment... [more]
RHO13.943e-5953.41GTP-binding protein of the rho subfamily of Ras-li... [more]
RHO52.976e-5542.11Non-essential small GTPase of the Rho/Rac family o... [more]
RHO32.473e-5044.44Non-essential small GTPase of the Rho/Rac family o... [more]
RHO45.944e-4947.43Non-essential small GTPase; member of the Rho/Rac ... [more]
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BLAST of Rac-1 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 5
Match NameE-valueIdentityDescription
EDO385369.326e-11281.44Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO350197.767e-10179.66Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO374721.220e-8866.49Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO394651.377e-6354.91Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO365531.087e-5760.69Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
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BLAST of Rac-1 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5
Match NameE-valueIdentityDescription
ENSORLT00000041989.15.169e-11183.24Rac family small GTPase 2 [Source:NCBI gene;Acc:10... [more]
ENSORLT00000038381.12.602e-11081.25ras-related C3 botulinum toxin substrate 1 [Source... [more]
RAC14.591e-10884.18ras-related C3 botulinum toxin substrate 1 [Source... [more]
RAC14.591e-10884.18ras-related C3 botulinum toxin substrate 1 [Source... [more]
rac3b4.389e-10282.08ras-related C3 botulinum toxin substrate 3 [Source... [more]
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BLAST of Rac-1 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5
Match NameE-valueIdentityDescription
SMESG000024961.14.393e-138100.00SMESG000024961.1[more]
SMESG000024968.16.312e-10780.63SMESG000024968.1[more]
SMESG000005010.11.091e-8766.49SMESG000005010.1[more]
SMESG000064161.13.093e-8061.03SMESG000064161.1[more]
SMESG000005012.11.706e-7964.04SMESG000005012.1[more]
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Cross References
External references for this transcript
DatabaseAccession
SmedGD GBrowseSMED30013863
GenBankADW66119.1
Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30013863 ID=SMED30013863|Name=Rac-1|organism=Schmidtea mediterranea sexual|type=transcript|length=1606bp
AATTGATTCTATTTCTGTTGATAGATTGAAATATAATTACAAATTACGGA
ATTCAGATTTCATGTTATAATTTATTCACTTTATTATTATTTTACAGTAT
AAATTGAAATCCGAAAATATTATATTTAATTTAGAAAACAAAATTTCTCT
TAAATTATAAATAATGCAAGGTATAAAATGTGTTGTTGTTGGTGACGGAG
CAGTAGGTAAAACGTGCTTGCTAATTAGCTACACAACAAACGCTTTTCCT
GGGGAATATATTCCTACAGTTTTCGATAATTATTCAGCTAATGTGATGGT
CGATAACAAACCTGTGAATCTTGGATTGTGGGATACTGCAGGCCAAGAAG
ACTATGACAGATTGCGGCCACTGTCATATCCACAAACGGATGTTTTTCTC
ATTTGTTTTTCACTTATCAATTCATCATCATACGAAAATGTGCGTGCTAA
ATGGTATCCGGAAATAACCCATCACTGTCCGAACACACCGATAATTCTCG
TTGGAACAAAGCTCGATTTGCGAGAAAACCATATGAATGGCGAGGCTGGT
AAAGATCGTCGAAATACTCCCATTAGTTATCCACAGGGACTAGTATTGGC
CAAAGAAATCGGAGCCGTGAAATACTTAGAGTGCTCAGCTCTCACTCAAA
AAGGTCTAAAAAGTGTGTTCGATGAGGCAATTCGTGCAGTGTTATGCCCA
AAACCACCACGCAAGAAGACCTGTAAATTTCTATGAAGAATGCACAATTT
TATTGATGAAATAACAAACAAATTCACGTTTTATATATCTGTCTCTTTCT
CTTTGACAAATTCATCTGTAATGTTGGGCTATTATTCATTTATTTTGTCT
GCATATTATTCACTGGAAAACAACAACAACATTCATCGATTTTCTTCAAT
ATTTAACAAATATTAATCAATAATATTATTATTTCTATTATAAAACTAAA
CTATTTTGCCTTGATTGATTTTTTAGTTGAAATATTAATAAAATTGATTT
TTCGAATATCTCACTATCGATTTGTCTCAATTATCGATTTTGTTTGTCCA
TGGACTTGATCGTGTGATGTCAGAATATGATATATTATATAGTTATTATT
CAACTTTTTGTTGTTGTTGTTTATGTTGTTATTATTATTATTATTGCTGG
TTAATTGATTTTCTATTGGATTTTCATTCATTTCCGTCGTCCGTGCGCCA
TTGTTAGCGATGTCGGAAACGTAATTCGTAGGCAAATGAACATGATGCTA
TTCTGTATATCTAATATTTTCATAAATGTATTTTTATATACATAATTAGG
CATTGTCAATATTGGAACCGATATTCGAATGGTAAAACATTGTTACCATA
CAATTTTGTTGTGTAAAAATTAATAAATGATTAATAATTGCTTTATCGAG
TTATTTGCGGGCAATTCTACAGTTGAGATGTTTTGTAAACGTTTGATTTG
TTATTATTTTTCACAAGTGCGATCCTATTGGCTAGTATCATAAACTGATT
AATTGCGCGCGTAAATTTGGAAGCTCTAAATTTAATCTATATCTTCATTT
AATTTTATTAATTCTGACAATTTTCTATTTTTATTTGCAAATCATTTATA
ATTTTG
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protein sequence of SMED30013863-orf-1

>SMED30013863-orf-1 ID=SMED30013863-orf-1|Name=SMED30013863-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=191bp
MQGIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDNKP
VNLGLWDTAGQEDYDRLRPLSYPQTDVFLICFSLINSSSYENVRAKWYPE
ITHHCPNTPIILVGTKLDLRENHMNGEAGKDRRNTPISYPQGLVLAKEIG
AVKYLECSALTQKGLKSVFDEAIRAVLCPKPPRKKTCKFL*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000020protonephridia
PLANA:0000026gut
PLANA:0000070intestinal phagocyte
PLANA:0000103central nervous system
PLANA:0000429neoblast
PLANA:0003116parenchymal cell
Vocabulary: INTERPRO
TermDefinition
IPR005225Small_GTP-bd_dom
IPR003578Small_GTPase_Rho
IPR001806Small_GTPase
IPR027417P-loop_NTPase
Vocabulary: biological process
TermDefinition
GO:0007264small GTPase mediated signal transduction
GO:0001934positive regulation of protein phosphorylation
GO:0002093auditory receptor cell morphogenesis
GO:0002551mast cell chemotaxis
GO:0003382epithelial cell morphogenesis
GO:0006897endocytosis
GO:0006911phagocytosis, engulfment
GO:0006935chemotaxis
GO:0006972hyperosmotic response
GO:0007010cytoskeleton organization
GO:0007015actin filament organization
GO:0007155cell adhesion
GO:0007186G-protein coupled receptor signaling pathway
GO:0007411axon guidance
GO:0008283cell proliferation
GO:0008361regulation of cell size
GO:0010592positive regulation of lamellipodium assembly
GO:0010762regulation of fibroblast migration
GO:0010811positive regulation of cell-substrate adhesion
GO:0014041regulation of neuron maturation
GO:0016358dendrite development
GO:0016477cell migration
GO:0016601Rac protein signal transduction
GO:0021799cerebral cortex radially oriented cell migration
GO:0021831embryonic olfactory bulb interneuron precursor migration
GO:0021894cerebral cortex GABAergic interneuron development
GO:0022604regulation of cell morphogenesis
GO:0030032lamellipodium assembly
GO:0030036actin cytoskeleton organization
GO:0030041actin filament polymerization
GO:0030334regulation of cell migration
GO:0030838positive regulation of actin filament polymerization
GO:0031529ruffle organization
GO:0032707negative regulation of interleukin-23 production
GO:0034446substrate adhesion-dependent cell spreading
GO:0035567non-canonical Wnt signaling pathway
GO:0043552positive regulation of phosphatidylinositol 3-kinase activity
GO:0043652engulfment of apoptotic cell
GO:0045216cell-cell junction organization
GO:0045453bone resorption
GO:0045740positive regulation of DNA replication
GO:0051894positive regulation of focal adhesion assembly
GO:0051932synaptic transmission, GABAergic
GO:0060071Wnt signaling pathway, planar cell polarity pathway
GO:0060263regulation of respiratory burst
GO:0060999positive regulation of dendritic spine development
GO:0071260cellular response to mechanical stimulus
GO:0071526semaphorin-plexin signaling pathway
GO:0071542dopaminergic neuron differentiation
GO:0072659protein localization to plasma membrane
GO:0090023positive regulation of neutrophil chemotaxis
GO:0090103cochlea morphogenesis
GO:0097178ruffle assembly
GO:1900026positive regulation of substrate adhesion-dependent cell spreading
GO:1904948midbrain dopaminergic neuron differentiation
GO:0048168regulation of neuronal synaptic plasticity
GO:0048532anatomical structure arrangement
GO:0048812neuron projection morphogenesis
GO:0048813dendrite morphogenesis
GO:0048870cell motility
GO:0048873homeostasis of number of cells within a tissue
GO:0051496positive regulation of stress fiber assembly
GO:0051668localization within membrane
Vocabulary: molecular function
TermDefinition
GO:0005525GTP binding
GO:0000166nucleotide binding
GO:0003924GTPase activity
GO:0005515protein binding
GO:0017137Rab GTPase binding
GO:0019899enzyme binding
GO:0019901protein kinase binding
GO:0030742GTP-dependent protein binding
GO:0031996thioesterase binding
GO:0042826histone deacetylase binding
GO:0051022Rho GDP-dissociation inhibitor binding
GO:0051117ATPase binding
Vocabulary: cellular component
TermDefinition
GO:0000139Golgi membrane
GO:0000242pericentriolar material
GO:0001891phagocytic cup
GO:0005634nucleus
GO:0005737cytoplasm
GO:0005802trans-Golgi network
GO:0005829cytosol
GO:0005884actin filament
GO:0005886plasma membrane
GO:0005925focal adhesion
GO:0016020membrane
GO:0019897extrinsic component of plasma membrane
GO:0030027lamellipodium
GO:0031012extracellular matrix
GO:0031410cytoplasmic vesicle
GO:0031901early endosome membrane
GO:0032587ruffle membrane
GO:0036464cytoplasmic ribonucleoprotein granule
GO:0042470melanosome
GO:0042995cell projection
GO:0043197dendritic spine
GO:0060091kinocilium
GO:0070062extracellular exosome
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
NoneNo IPR availablePRINTSPR00449RASTRNSFRMNGcoord: 44..66
score: 48.13
coord: 154..176
score: 31.62
coord: 106..119
score: 52.22
coord: 4..25
score: 49.32
coord: 27..43
score: 30.58
NoneNo IPR availableSMARTSM00176ran_sub_2coord: 9..189
e-value: 0.0026
score: -1.1
NoneNo IPR availableSMARTSM00173ras_sub_4coord: 1..179
e-value: 1.3E-17
score: 74.5
NoneNo IPR availableSMARTSM00174rho_sub_3coord: 6..179
e-value: 3.6E-129
score: 445.1
NoneNo IPR availableSMARTSM00175rab_sub_5coord: 4..179
e-value: 1.1E-13
score: 61.0
NoneNo IPR availableGENE3DG3DSA:3.40.50.300coord: 1..182
e-value: 8.9E-75
score: 251.9
NoneNo IPR availablePANTHERPTHR24072RHO FAMILY GTPASEcoord: 1..189
NoneNo IPR availablePANTHERPTHR24072:SF169RAS-RELATED C3 BOTULINUM TOXIN SUBSTRATE 2coord: 1..189
IPR001806Small GTPasePFAMPF00071Rascoord: 5..177
e-value: 1.4E-55
score: 187.3
IPR005225Small GTP-binding protein domainTIGRFAMTIGR00231TIGR00231coord: 1..127
e-value: 2.7E-37
score: 126.0
IPR003578Small GTPase RhoPROSITEPS51420RHOcoord: 1..176
score: 28.464
IPR027417P-loop containing nucleoside triphosphate hydrolaseSUPERFAMILYSSF52540P-loop containing nucleoside triphosphate hydrolasescoord: 4..176