Neutral cholesterol ester hydrolase 1

Overview
NameNeutral cholesterol ester hydrolase 1
Smed IDSMED30013846
Length (bp)1393
Neoblast Clusters

Zeng et. al., 2018



▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)



Explore this single cell expression dataset with our NB Cluster Shiny App



 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of Neutral cholesterol ester hydrolase 1 (SMED30013846) t-SNE clustered cells

Violin plots show distribution of expression levels for Neutral cholesterol ester hydrolase 1 (SMED30013846) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of Neutral cholesterol ester hydrolase 1 (SMED30013846) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for Neutral cholesterol ester hydrolase 1 (SMED30013846) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020



SMED30013846

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 4

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
epidermisSMED30013846SMESG000076519.1 SMESG000076513.1 SMESG000076505.1 SMESG000076502.1 dd_Smed_v4_4674_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
Smed sexual biotypeSMED30013846SMESG000046779.1 SMESG000076513.1 SMESG000076502.1 SMESG000024883.1 SMESG000024882.1 SMESG000024707.1 Contig46395newmark_estsPMID:29674431
Fincher et al., 2018		FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
Smed sexual biotypeSMED30013846SMESG000046779.1 SMESG000076513.1 SMESG000076502.1 SMESG000024883.1 SMESG000024882.1 SMESG000024707.1 Contig46395uc_Smed_v2PMID:29674431
Fincher et al., 2018		FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
epidermisSMED30013846SMESG000076519.1 SMESG000076513.1 SMESG000076505.1 SMESG000076502.1 dd_Smed_v4_4674_0_1dd_Smed_v4PMID:28292427
Wurtzel et al., 2017		whole organism asexual adult single-cell RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
[Close]
BLAST of Neutral cholesterol ester hydrolase 1 vs. Ensembl Human
Match: NCEH1 (neutral cholesterol ester hydrolase 1 [Source:HGNC Symbol;Acc:HGNC:29260])

HSP 1 Score: 152.525 bits (384), Expect = 5.575e-41
Identity = 115/359 (32.03%), Postives = 183/359 (50.97%), Query Frame = 1 
Query:  265 LGKLNYYMSDKTNLTIKRKLFDGVNVLVFS-------PIKRDRKGPAIVYYHGGGWAVMNPEI--YSPFLANLARRLNTMIVAVDYRKAPEYPYPAPFNDALVATKYFLIN--CKEFDVDPNRIALMGDSAGGSLVVSVGYHLTAMKRASKIVHSPKVLISLNPVLQVVDFSTPSYRDNLHDPILVKARMARYYCIYAFGEQLSWTELRNCIEALI--SHRHLTVEAIQKVRGHVDWNNLLSGRGYDNRPRSSFTQSVNQFSEKLSELVESVGFSPLSALNDSQLQILPPVYVYGSSKDPLRDDAKMLVARLKRLRSFG-----DYWEFKCFHVCFLLG------RIGVKDEETSLKEL 1269
             GK + + S +  +T     FDGV V VF        P+KR     ++VY HGGGWA+ + +I  Y      +A  LN +IV+++YR  P+  +P   +D + ATKYFL     +++ VDP RI + GDSAGG+L  ++G   T   + + + +  K+   + PVLQ +DF+TPSY+ N++ PIL +  M +Y+  Y  G         + ++A+I  +H  L VE    VR  ++W +LL      N      T    +  ++L +L+++   +PL A + + LQ+LP  Y+     D LRDD  M     KRL S G     D++E   FH C +         +G++   + +K L
Sbjct:   69 FGKKSAWSSAQVKVTDTD--FDGVEVRVFEGPPKPEEPLKR-----SVVYIHGGGWALASAKIRYYDELCTAMAEELNAVIVSIEYRLVPKVYFPEQIHDVVRATKYFLKPEVLQKYMVDPGRICISGDSAGGNLAAALGQQFT---QDASLKNKLKLQALIYPVLQALDFNTPSYQQNVNTPILPRYVMVKYWVDYFKGN-------YDFVQAMIVNNHTSLDVEEAAAVRARLNWTSLLPASFTKNYKPVVQTTGNARIVQELPQLLDARS-APLIA-DQAVLQLLPKTYILTCEHDVLRDDGIMYA---KRLESAGVEVTLDHFE-DGFHGCMIFTSWPTNFSVGIRTRNSYIKWL 404
[Close]
BLAST of Neutral cholesterol ester hydrolase 1 vs. Ensembl Human
Match: NCEH1 (neutral cholesterol ester hydrolase 1 [Source:HGNC Symbol;Acc:HGNC:29260])

HSP 1 Score: 152.14 bits (383), Expect = 1.495e-40
Identity = 115/359 (32.03%), Postives = 183/359 (50.97%), Query Frame = 1 
Query:  265 LGKLNYYMSDKTNLTIKRKLFDGVNVLVFS-------PIKRDRKGPAIVYYHGGGWAVMNPEI--YSPFLANLARRLNTMIVAVDYRKAPEYPYPAPFNDALVATKYFLIN--CKEFDVDPNRIALMGDSAGGSLVVSVGYHLTAMKRASKIVHSPKVLISLNPVLQVVDFSTPSYRDNLHDPILVKARMARYYCIYAFGEQLSWTELRNCIEALI--SHRHLTVEAIQKVRGHVDWNNLLSGRGYDNRPRSSFTQSVNQFSEKLSELVESVGFSPLSALNDSQLQILPPVYVYGSSKDPLRDDAKMLVARLKRLRSFG-----DYWEFKCFHVCFLLG------RIGVKDEETSLKEL 1269
             GK + + S +  +T     FDGV V VF        P+KR     ++VY HGGGWA+ + +I  Y      +A  LN +IV+++YR  P+  +P   +D + ATKYFL     +++ VDP RI + GDSAGG+L  ++G   T   + + + +  K+   + PVLQ +DF+TPSY+ N++ PIL +  M +Y+  Y  G         + ++A+I  +H  L VE    VR  ++W +LL      N      T    +  ++L +L+++   +PL A + + LQ+LP  Y+     D LRDD  M     KRL S G     D++E   FH C +         +G++   + +K L
Sbjct:  101 FGKKSAWSSAQVKVTDTD--FDGVEVRVFEGPPKPEEPLKR-----SVVYIHGGGWALASAKIRYYDELCTAMAEELNAVIVSIEYRLVPKVYFPEQIHDVVRATKYFLKPEVLQKYMVDPGRICISGDSAGGNLAAALGQQFT---QDASLKNKLKLQALIYPVLQALDFNTPSYQQNVNTPILPRYVMVKYWVDYFKGN-------YDFVQAMIVNNHTSLDVEEAAAVRARLNWTSLLPASFTKNYKPVVQTTGNARIVQELPQLLDARS-APLIA-DQAVLQLLPKTYILTCEHDVLRDDGIMYA---KRLESAGVEVTLDHFE-DGFHGCMIFTSWPTNFSVGIRTRNSYIKWL 436
[Close]
BLAST of Neutral cholesterol ester hydrolase 1 vs. Ensembl Human
Match: NCEH1 (neutral cholesterol ester hydrolase 1 [Source:HGNC Symbol;Acc:HGNC:29260])

HSP 1 Score: 138.272 bits (347), Expect = 2.166e-35
Identity = 116/367 (31.61%), Postives = 183/367 (49.86%), Query Frame = 1 
Query:  265 LGKLNYYMSDKTNLTIKRKLFDGVNVLVFS-------PIKRDRKGPAIVYYHGGGWAVM--------NPEI--YSPFLANLARRLNTMIVAVDYRKAPEYPYPAPFNDALVATKYFLIN--CKEFDVDPNRIALMGDSAGGSLVVSVGYHLTAMKRASKIVHSPKVLISLNPVLQVVDFSTPSYRDNLHDPILVKARMARYYCIYAFGEQLSWTELRNCIEALI--SHRHLTVEAIQKVRGHVDWNNLLSGRGYDNRPRSSFTQSVNQFSEKLSELVESVGFSPLSALNDSQLQILPPVYVYGSSKDPLRDDAKMLVARLKRLRSFG-----DYWEFKCFHVCFLLG------RIGVKDEETSLKEL 1269
             GK + + S +  +T     FDGV V VF        P+KR     ++VY HGGGWA+         + EI  Y      +A  LN +IV+++YR  P+  +P   +D + ATKYFL     +++ VDP RI + GDSAGG+L  ++G   T   + + + +  K+   + PVLQ +DF+TPSY+ N++ PIL +  M +Y+  Y  G         + ++A+I  +H  L VE    VR  ++W +LL      N      T    +  ++L +L+++   +PL A + + LQ+LP  Y+     D LRDD  M     KRL S G     D++E   FH C +         +G++   + +K L
Sbjct:  101 FGKKSAWSSAQVKVTDTD--FDGVEVRVFEGPPKPEEPLKR-----SVVYIHGGGWALASASASWSPSDEIRYYDELCTAMAEELNAVIVSIEYRLVPKVYFPEQIHDVVRATKYFLKPEVLQKYMVDPGRICISGDSAGGNLAAALGQQFT---QDASLKNKLKLQALIYPVLQALDFNTPSYQQNVNTPILPRYVMVKYWVDYFKGN-------YDFVQAMIVNNHTSLDVEEAAAVRARLNWTSLLPASFTKNYKPVVQTTGNARIVQELPQLLDARS-APLIA-DQAVLQLLPKTYILTCEHDVLRDDGIMYA---KRLESAGVEVTLDHFE-DGFHGCMIFTSWPTNFSVGIRTRNSYIKWL 444
[Close]
BLAST of Neutral cholesterol ester hydrolase 1 vs. Ensembl Human
Match: AADACL2 (arylacetamide deacetylase like 2 [Source:HGNC Symbol;Acc:HGNC:24427])

HSP 1 Score: 129.798 bits (325), Expect = 9.802e-33
Identity = 101/316 (31.96%), Postives = 164/316 (51.90%), Query Frame = 1 
Query:  244 YRCFESGLGKLNYY--MSDKTNLTIKRKLFDGVNVLVFSPIKR-DRKGPAIVYYHGGGWAVMNPEIYSPFLAN--LARRLNTMIVAVDYRKAPEYPYPAPFNDALVATKYFLIN--CKEFDVDPNRIALMGDSAGGSLVVSVGYHLTAMKRASKIVHSPKVLISLNPVLQVVDFSTPSYRDNLHDPILVKARMARYYCIY-AFGEQLSWTELRNCIEALISHRHLTVEAIQKVRGHVDWNNLLSGRGYDNRPRSSFTQSV-NQFSEKLSELVESVGFSPLSALNDSQLQILPPVYVYGSSKDPLRDDAKMLVARLK 1164
            Y  F S + +L+Y   +SD+  +T+    F  + V ++ P ++ + +  A++Y+HGGG+   + +  +    N   A  L+ ++V VDYR AP++ +PA F D L A K+FL+     ++ VDP RI + GDS+GG+L  +V   +   +  ++I H  K+ + L P LQ+ D   PS+R+N H  +L +    +   +Y    E L W   RN        +H+ +E+ + +   V+W+ LL  +    R    +T+ +    S  L  L +S    PL A NDSQLQ LP  Y+     D LRDD  M V RL+
Sbjct:   58 YEEFISMIFRLDYTQPLSDEY-ITVTDTTFVDIPVRLYLPKRKSETRRRAVIYFHGGGFCFGSSKQRAFDFLNRWTANTLDAVVVGVDYRLAPQHHFPAQFEDGLAAVKFFLLEKILTKYGVDPTRICIAGDSSGGNLATAVTQQV---QNDAEIKHKIKMQVLLYPGLQITDSYLPSHRENEHGIVLTRDVAIKLVSLYFTKDEALPWAMRRN--------QHMPLES-RHLFKFVNWSILLPEK---YRKDYVYTEPILGGLSYSLPGLTDSRAL-PLLA-NDSQLQNLPLTYILTCQHDLLRDDGLMYVTRLR 355
[Close]
BLAST of Neutral cholesterol ester hydrolase 1 vs. Ensembl Human
Match: AADACL2 (arylacetamide deacetylase like 2 [Source:HGNC Symbol;Acc:HGNC:24427])

HSP 1 Score: 129.798 bits (325), Expect = 9.802e-33
Identity = 101/316 (31.96%), Postives = 164/316 (51.90%), Query Frame = 1 
Query:  244 YRCFESGLGKLNYY--MSDKTNLTIKRKLFDGVNVLVFSPIKR-DRKGPAIVYYHGGGWAVMNPEIYSPFLAN--LARRLNTMIVAVDYRKAPEYPYPAPFNDALVATKYFLIN--CKEFDVDPNRIALMGDSAGGSLVVSVGYHLTAMKRASKIVHSPKVLISLNPVLQVVDFSTPSYRDNLHDPILVKARMARYYCIY-AFGEQLSWTELRNCIEALISHRHLTVEAIQKVRGHVDWNNLLSGRGYDNRPRSSFTQSV-NQFSEKLSELVESVGFSPLSALNDSQLQILPPVYVYGSSKDPLRDDAKMLVARLK 1164
            Y  F S + +L+Y   +SD+  +T+    F  + V ++ P ++ + +  A++Y+HGGG+   + +  +    N   A  L+ ++V VDYR AP++ +PA F D L A K+FL+     ++ VDP RI + GDS+GG+L  +V   +   +  ++I H  K+ + L P LQ+ D   PS+R+N H  +L +    +   +Y    E L W   RN        +H+ +E+ + +   V+W+ LL  +    R    +T+ +    S  L  L +S    PL A NDSQLQ LP  Y+     D LRDD  M V RL+
Sbjct:   58 YEEFISMIFRLDYTQPLSDEY-ITVTDTTFVDIPVRLYLPKRKSETRRRAVIYFHGGGFCFGSSKQRAFDFLNRWTANTLDAVVVGVDYRLAPQHHFPAQFEDGLAAVKFFLLEKILTKYGVDPTRICIAGDSSGGNLATAVTQQV---QNDAEIKHKIKMQVLLYPGLQITDSYLPSHRENEHGIVLTRDVAIKLVSLYFTKDEALPWAMRRN--------QHMPLES-RHLFKFVNWSILLPEK---YRKDYVYTEPILGGLSYSLPGLTDSRAL-PLLA-NDSQLQNLPLTYILTCQHDLLRDDGLMYVTRLR 355
[Close]
BLAST of Neutral cholesterol ester hydrolase 1 vs. Ensembl Celegans
Match: nceh-1 (Neutral Cholesterol Ester Hydrolase homolog [Source:UniProtKB/TrEMBL;Acc:F0IWV1])

HSP 1 Score: 106.686 bits (265), Expect = 7.234e-25
Identity = 83/288 (28.82%), Postives = 142/288 (49.31%), Query Frame = 1 
Query:  325 FDGVNVLVFSP-IKRDRKGPAIVYYHGGGWAVMNPEIYSPFLANLARRLNTMIVAVDYRKAPEYPYPAPFNDALVATKYFLINCKE-FDVDPNRIALMGDSAGGSLVVSVGYHLTAMKRASKIVHSPKVL--ISLNPVLQVVDFSTPSYR---DNLHDPILVK-ARMARYYCIYAFGEQLSWTELRNCIEALISHRHLTVEAIQKVRGHVDWNNLLSGRGYDNRPRSSFTQSVNQFSEKLSELVESVGFSP-LSALNDSQLQILPPVYVYGSSKDPLRDDAKMLVARL 1161
            ++GV+V  + P +  +    A+++ HGGG+A+ +  +Y      +A+ +NT +V++DYR +PE  +P    D   A  YFL N  E F +DP ++ L+GDSAGG+L  ++     A +RA K    PK+L  + L P+LQ+VD    SYR     L     V  A +A YY +YA    +   + +  +  ++++ H+  +  +K+   + +   +      N  +      + + SE    L+E V F P  S +    L+ LP   +     D LRD+  +   RL
Sbjct:  103 WNGVHVRTYEPRLVENSTDGAVIFIHGGGFAIGSVAMYDSLTRRMAKSMNTFVVSIDYRLSPETVFPENLLDCEKAIDYFLENSLEKFKIDPKKVILVGDSAGGNLATAI-----AQRRAEKGAE-PKLLAQVLLYPLLQLVDLQMTSYRYFHKRLTGIAFVDPASVAFYYMLYA---GIPLEKAKELVPIVLTNGHVKPDYREKIDKLLTYRTTIESTHTYNTTKIPKRWEIVENSEA-QNLLEKVIFDPNFSPIMRENLENLPKSLIVTCEYDVLRDEGLIYSERL 380
[Close]
BLAST of Neutral cholesterol ester hydrolase 1 vs. Ensembl Celegans
Match: T09B9.1 (pep chromosome:WBcel235:X:9757271:9759306:1 gene:WBGene00011642.1 transcript:T09B9.1.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:T09B9.1)

HSP 1 Score: 103.605 bits (257), Expect = 8.112e-24
Identity = 86/323 (26.63%), Postives = 152/323 (47.06%), Query Frame = 1 
Query:  235 KGVYRCFESGLGKLNYYMSDKTNLTIKRKLFDGVNVLVFSPIK-RDRKGPAIVYYHGGGWAVMNPEIYSPFLANLARRLNTMIVAVDYRKAPEYPYPAPFNDALVATKY-FLINCKEFDVDPNRIALMGDSAGGSLVVSVGYHLTAMKRASKIVHSPKVLISLNPVLQVVDFSTPSYR---DNLHDPILVKARMARYYCIYAFGEQLSWTELRNCIEALISHRHLTVEAIQKVRGHVDWNNLL-SGRGYDNRP-------RSSFTQSVNQFSEKLSELVESVGFSPLSALNDSQLQILPPVYVYGSSKDPLRDDAKMLVARLK 1164
            +G        LG +   ++    + IK  +++G  V V+ PI  +     A+++ HGGG+A+ N E+Y   +  +A  + T+ ++++YR +PE  +P    D   A ++ F     +F +D ++I +MGDSAGG++   +     A     K+  + +VLI   P+LQ+ D  T SYR     L+   LV      YY  Y F   ++  E    + ++IS+ H++     +V   +++ +++ S R Y N         R SF     +  + +   + +  FSPL   + S    LPP  V     D LRD+  +   RL+
Sbjct:   78 RGALNLLSKSLGLM---VNTHGQIDIKWHVWNGTPVKVYQPINNKTATNGAVIFIHGGGFALGNVEMYDSLVKRMAFEMRTLFISIEYRLSPETVFPGGIMDCEAAIEHLFEFGAVQFGIDTSKIVIMGDSAGGNMATVIAQRRAARNAFPKL--AGQVLIY--PLLQMADLQTVSYRYFHSRLNGYALVDPESVVYY--YMFYAGINMDEKAYLVPSVISNGHVSDSLKSEVDKMMEYEHIIESTRTYKNHSIPCRWPVRPSF-----EAQQLMEPFLNNPDFSPLMKKDVSN---LPPTMVVTCEFDILRDEGLIYAHRLE 383
[Close]
BLAST of Neutral cholesterol ester hydrolase 1 vs. Ensembl Celegans
Match: nceh-1 (Neutral Cholesterol Ester Hydrolase homolog [Source:UniProtKB/TrEMBL;Acc:F0IWV1])

HSP 1 Score: 95.5153 bits (236), Expect = 3.410e-21
Identity = 82/288 (28.47%), Postives = 138/288 (47.92%), Query Frame = 1 
Query:  325 FDGVNVLVFSP-IKRDRKGPAIVYYHGGGWAVMNPEIYSPFLANLARRLNTMIVAVDYRKAPEYPYPAPFNDALVATKYFLINCKE-FDVDPNRIALMGDSAGGSLVVSVGYHLTAMKRASKIVHSPKVL--ISLNPVLQVVDFSTPSYR---DNLHDPILVK-ARMARYYCIYAFGEQLSWTELRNCIEALISHRHLTVEAIQKVRGHVDWNNLLSGRGYDNRPRSSFTQSVNQFSEKLSELVESVGFSP-LSALNDSQLQILPPVYVYGSSKDPLRDDAKMLVARL 1161
            ++GV+V  + P +  +    A+++ HGGG+A+ +  I           +NT +V++DYR +PE  +P    D   A  YFL N  E F +DP ++ L+GDSAGG+L  ++     A +RA K    PK+L  + L P+LQ+VD    SYR     L     V  A +A YY +YA    +   + +  +  ++++ H+  +  +K+   + +   +      N  +      + + SE    L+E V F P  S +    L+ LP   +     D LRD+  +   RL
Sbjct:  103 WNGVHVRTYEPRLVENSTDGAVIFIHGGGFAIGSVAI-----------MNTFVVSIDYRLSPETVFPENLLDCEKAIDYFLENSLEKFKIDPKKVILVGDSAGGNLATAI-----AQRRAEKGA-EPKLLAQVLLYPLLQLVDLQMTSYRYFHKRLTGIAFVDPASVAFYYMLYA---GIPLEKAKELVPIVLTNGHVKPDYREKIDKLLTYRTTIESTHTYNTTKIPKRWEIVENSEA-QNLLEKVIFDPNFSPIMRENLENLPKSLIVTCEYDVLRDEGLIYSERL 369
[Close]
BLAST of Neutral cholesterol ester hydrolase 1 vs. Ensembl Celegans
Match: trcs-1 (TRansport of membrane to Cell Surface [Source:UniProtKB/TrEMBL;Acc:Q19839])

HSP 1 Score: 90.1225 bits (222), Expect = 2.964e-19
Identity = 84/318 (26.42%), Postives = 144/318 (45.28%), Query Frame = 1 
Query:  235 KGVYRCFESGLGKLNYYMSDKTNLTIKRKLFDGVNVLVFSPIK-RDRKGPAIVYYHGGGWAVMNPEIYSPFLANLARRLNTMIVAVDYRKAPEYPYPAPFNDALVATKYFL-INCKEFDVDPNRIALMGDSAGGSLVVSVGYHLTAMKRASKIVHSPKVLISLNPVLQVVDFSTPSYR---DNLHDPILVKARMARYYCIYAFGEQLSWTELRNCIEALISHRHLTVEAIQKVRGHVDWNNLLSGRGYDNRPRSSFTQ--SVNQFSEKLSELVESVGFSP-LSALNDSQLQILPPVYVYGSSKDPLRDDAKMLVARLK 1164
            +G        LG L   ++    + IK   ++   V V+ P   +     A+++ HGGG+A+ N ++Y   +  +A  + T+ ++++YR +PE  +P    D   A  +F      +F V+ +++ +MGDSAGG+L   +     A     K+  + +VLI   P+LQ+ D  T SYR     L    LV      YY  Y F   +   E    + ++IS+ H+      +    + + +++  +   N    S T+   V+Q S +  +L+E    +P  S L    L  LPP  V     D LRD+  +   RLK
Sbjct:   77 RGALNTLSKTLGLL---VNTHGQVDIKWHKWNETPVKVYRPTNNKTSTDGAVLFIHGGGFALGNVDMYDSLVKRMAYEMKTLFISIEYRLSPETVFPGGILDCEAAIDHFFDFGAVQFGVNTSKVVIMGDSAGGNLATVIAQRRAARNSFPKL--AGQVLIY--PLLQMADMQTVSYRYFHSRLRGYALVDPESVAYY--YMFYAGIDMDEKAYLVPSVISNGHVANHLQSEASEIMSYKSVIEMK--HNYKNHSITERWEVSQ-SYEAQDLMEPFLTNPDFSPLMRKDLSNLPPTMVITCEFDILRDEGLIYGERLK 382
[Close]
BLAST of Neutral cholesterol ester hydrolase 1 vs. Ensembl Celegans
Match: trcs-1 (TRansport of membrane to Cell Surface [Source:UniProtKB/TrEMBL;Acc:Q19839])

HSP 1 Score: 90.1225 bits (222), Expect = 2.964e-19
Identity = 84/318 (26.42%), Postives = 144/318 (45.28%), Query Frame = 1 
Query:  235 KGVYRCFESGLGKLNYYMSDKTNLTIKRKLFDGVNVLVFSPIK-RDRKGPAIVYYHGGGWAVMNPEIYSPFLANLARRLNTMIVAVDYRKAPEYPYPAPFNDALVATKYFL-INCKEFDVDPNRIALMGDSAGGSLVVSVGYHLTAMKRASKIVHSPKVLISLNPVLQVVDFSTPSYR---DNLHDPILVKARMARYYCIYAFGEQLSWTELRNCIEALISHRHLTVEAIQKVRGHVDWNNLLSGRGYDNRPRSSFTQ--SVNQFSEKLSELVESVGFSP-LSALNDSQLQILPPVYVYGSSKDPLRDDAKMLVARLK 1164
            +G        LG L   ++    + IK   ++   V V+ P   +     A+++ HGGG+A+ N ++Y   +  +A  + T+ ++++YR +PE  +P    D   A  +F      +F V+ +++ +MGDSAGG+L   +     A     K+  + +VLI   P+LQ+ D  T SYR     L    LV      YY  Y F   +   E    + ++IS+ H+      +    + + +++  +   N    S T+   V+Q S +  +L+E    +P  S L    L  LPP  V     D LRD+  +   RLK
Sbjct:   77 RGALNTLSKTLGLL---VNTHGQVDIKWHKWNETPVKVYRPTNNKTSTDGAVLFIHGGGFALGNVDMYDSLVKRMAYEMKTLFISIEYRLSPETVFPGGILDCEAAIDHFFDFGAVQFGVNTSKVVIMGDSAGGNLATVIAQRRAARNSFPKL--AGQVLIY--PLLQMADMQTVSYRYFHSRLRGYALVDPESVAYY--YMFYAGIDMDEKAYLVPSVISNGHVANHLQSEASEIMSYKSVIEMK--HNYKNHSITERWEVSQ-SYEAQDLMEPFLTNPDFSPLMRKDLSNLPPTMVITCEFDILRDEGLIYGERLK 382
[Close]
BLAST of Neutral cholesterol ester hydrolase 1 vs. Ensembl Fly
Match: Hsl (gene:FBgn0034491 transcript:FBtr0086270)

HSP 1 Score: 59.6918 bits (143), Expect = 3.469e-9
Identity = 45/162 (27.78%), Postives = 79/162 (48.77%), Query Frame = 1 
Query:  379 PAIVYY-HGGGWAVMNPEIYSPFLANLARRLNTMIVAVDYRKAPEYPYPAPFNDALVATKYFLINCKEFDVDPNRIALMGDSAGGSLVVSVGYHLTAMKRASKIVHSPKVLISLNPVLQVVDFSTPSYRDNLHDPILVKARMARYYCIYAFGEQLSWTELRN 861
            P+I+++ HGGG+   + + +  +L + A  L+  I++VDY  APE P+P    +   A  + L N +       R+   GDSAG +L  S+G  L  +++  ++     + ++  P L V    +P+    L DP+L    M R  C+ A+      T  +N
Sbjct:  392 PSILFHCHGGGFVAQSSKSHELYLRDWAVALDCPILSVDYSLAPEAPFPRALQEVYYAYCWLLNNTELLGTTAERVVCAGDSAGANL--SIGVALKCIEQGVRVPDG--LFLAYCPTL-VSFVPSPARLLCLMDPLLPFGFMMR--CLRAYAAPAQETLQQN 546
[Close]
BLAST of Neutral cholesterol ester hydrolase 1 vs. Ensembl Fly
Match: Hsl (gene:FBgn0034491 transcript:FBtr0086271)

HSP 1 Score: 59.6918 bits (143), Expect = 3.469e-9
Identity = 45/162 (27.78%), Postives = 79/162 (48.77%), Query Frame = 1 
Query:  379 PAIVYY-HGGGWAVMNPEIYSPFLANLARRLNTMIVAVDYRKAPEYPYPAPFNDALVATKYFLINCKEFDVDPNRIALMGDSAGGSLVVSVGYHLTAMKRASKIVHSPKVLISLNPVLQVVDFSTPSYRDNLHDPILVKARMARYYCIYAFGEQLSWTELRN 861
            P+I+++ HGGG+   + + +  +L + A  L+  I++VDY  APE P+P    +   A  + L N +       R+   GDSAG +L  S+G  L  +++  ++     + ++  P L V    +P+    L DP+L    M R  C+ A+      T  +N
Sbjct:  392 PSILFHCHGGGFVAQSSKSHELYLRDWAVALDCPILSVDYSLAPEAPFPRALQEVYYAYCWLLNNTELLGTTAERVVCAGDSAGANL--SIGVALKCIEQGVRVPDG--LFLAYCPTL-VSFVPSPARLLCLMDPLLPFGFMMR--CLRAYAAPAQETLQQN 546
[Close]
BLAST of Neutral cholesterol ester hydrolase 1 vs. Ensembl Fly
Match: Hsl (gene:FBgn0034491 transcript:FBtr0086272)

HSP 1 Score: 59.6918 bits (143), Expect = 3.469e-9
Identity = 45/162 (27.78%), Postives = 79/162 (48.77%), Query Frame = 1 
Query:  379 PAIVYY-HGGGWAVMNPEIYSPFLANLARRLNTMIVAVDYRKAPEYPYPAPFNDALVATKYFLINCKEFDVDPNRIALMGDSAGGSLVVSVGYHLTAMKRASKIVHSPKVLISLNPVLQVVDFSTPSYRDNLHDPILVKARMARYYCIYAFGEQLSWTELRN 861
            P+I+++ HGGG+   + + +  +L + A  L+  I++VDY  APE P+P    +   A  + L N +       R+   GDSAG +L  S+G  L  +++  ++     + ++  P L V    +P+    L DP+L    M R  C+ A+      T  +N
Sbjct:  392 PSILFHCHGGGFVAQSSKSHELYLRDWAVALDCPILSVDYSLAPEAPFPRALQEVYYAYCWLLNNTELLGTTAERVVCAGDSAGANL--SIGVALKCIEQGVRVPDG--LFLAYCPTL-VSFVPSPARLLCLMDPLLPFGFMMR--CLRAYAAPAQETLQQN 546
[Close]
BLAST of Neutral cholesterol ester hydrolase 1 vs. Ensembl Fly
Match: alpha-Est7 (gene:FBgn0015575 transcript:FBtr0081550)

HSP 1 Score: 55.4546 bits (132), Expect = 7.193e-8
Identity = 35/105 (33.33%), Postives = 54/105 (51.43%), Query Frame = 1 
Query:  358 IKRDRKGPAIVYYHGGGWAV--MNPEIYSPFLANLARRLNTMIVAVDYR---------KAPEYPYP--APFNDALVATKYFLINCKEFDVDPNRIALMGDSAGGS 633
            +K D+  P +V+ HGGG+ +   N E Y P   +   + + ++V + YR         K+PE   P  A   D ++A K+   NC  F  DPN I + G+SAGG+
Sbjct:  121 VKPDKARPVMVWIHGGGFIIGEANREWYGP---DYFMKEDVVLVTIQYRLGALGFMSLKSPELNVPGNAGLKDQVLALKWIKNNCASFGGDPNCITVFGESAGGA 222
[Close]
BLAST of Neutral cholesterol ester hydrolase 1 vs. Ensembl Zebrafish
Match: nceh1b.1 (neutral cholesterol ester hydrolase 1b, tandem duplicate 1 [Source:ZFIN;Acc:ZDB-GENE-061110-43])

HSP 1 Score: 140.584 bits (353), Expect = 1.011e-36
Identity = 125/416 (30.05%), Postives = 201/416 (48.32%), Query Frame = 1 
Query:  103 VLIISVLIYKFVDFRRYDDFILRTAVNMHIFLMDADIILRS-IHIKGVYRCF--ESGLGKLNYY---MSDKTNLT-----IKRKLFDGVNVLVFSPIKRDRK-GPAIVYYHGGGWAVMNPEIYSPFLA--NLARRLNTMIVAVDYRKAPEYPYPAPFNDALVATKYFLIN--CKEFDVDPNRIALMGDSAGGSLVVSVGYHLTAMKRASKIVHSPKVLISLNPVLQVVDFSTPSYRDNLHDPILVKARMARYYCIYAFGEQLSWTELRNCIEALISHRHLTVEAIQKVRGHVDWNNLLSGRGYDNRPRSSFTQSVNQFSEKLSELVESVGFSPLSALNDSQLQILPPVYVYGSSKDPLRDDAKMLVARLKR--LRSFGDYWEFKCFHVC--FLLGRIGVKDEETSLKELISFFENN 1290
            +LI ++L+     +  Y    L T +     LM  D ++RS + +  +   F   S  G L Y+   M  K+NL+     I    F GV  LVF    +++     +VY HGGGW V + ++ + +L    +A++L+ ++++V+YR AP+  +P  +ND   A K+ L       + +DP R+A+ GDSAGG+L  +V      M   S +    K+   + PVLQ +DF+TPSY+ N   PIL +  MAR++  Y  GEQ+    L   + A I         I+  R  +DW  LL      +    S      +  EKL  L++ V  +PL A ++  L+ +PP Y+     D LRDD  M   RL++  +  + D++E   FH C  F  G +  +    S    I + ++N
Sbjct:    4 ILIATILLSIAAAYYIY--IPLPTTITEPWKLMYTDAMIRSSMQLSFLAHDFGLTSPFGFLKYFSSLMDVKSNLSCSNVRITEASFGGVEALVFESTAQEKSLKRGVVYLHGGGWTVGSAKMEAYYLQCMEMAKQLDAVVLSVEYRLAPDGRFPDQYNDVFQAAKHILTAEVLSRYSIDPKRVAVSGDSAGGNLAAAV---AQQMAVDSSVPIKFKLQALIYPVLQGLDFNTPSYQQNAFTPILYRPLMARFWLEYLNGEQI----LLPTMLANIQSAQDQGPKIEAARAKIDWTLLLPVAFQKSYKPVSPLHGDPKLLEKLPGLLD-VRAAPLLAESEV-LKAVPPAYIMTCEHDVLRDDGLMYATRLQQAGVHVYLDHYE-DGFHGCLSFGFGPLSFEVGRRSFGNYIQWLKDN 407
[Close]
BLAST of Neutral cholesterol ester hydrolase 1 vs. Ensembl Zebrafish
Match: aadac (arylacetamide deacetylase [Source:ZFIN;Acc:ZDB-GENE-130530-713])

HSP 1 Score: 139.813 bits (351), Expect = 1.800e-36
Identity = 101/305 (33.11%), Postives = 153/305 (50.16%), Query Frame = 1 
Query:  304 LTIKRKLFDGVNVLVFSPIKRDRKGP---AIVYYHGGGWAV----MNPEIYSPFLANLARRLNTMIVAVDYRKAPEYPYPAPFNDALVATKYFLIN--CKEFDVDPNRIALMGDSAGGSLVVSVGYHLTAMKRASKIVHSPKVLISLN------PVLQVVDFSTPSYRDNLHDPILVKARMARYYCIYAFGEQLSWTELRNCIEALISHRHLTVEAIQKVRGHVDWNNLLSG---RGYDNRPRSSFTQSVNQFSEKLSELVESVGFSPLSALNDSQLQILPPVYVYGSSKDPLRDDAKMLVARLK 1164
            + +  + FDGV V+V+ P + ++ G    AI+Y HGGGW +    M P  Y     ++ + LN +IVAV+YR AP Y +P  F D     KYFL N   K ++++P RIA+ GDSAGG+L  +V         A ++   P+  I L       PVLQ +D  TPSY+ N H PIL +  M R++  Y       +T  ++ + A++++ H   E+   ++  V+W++ L     + Y+       T      S     L+     SPL  + D+ L+ LP  YV     D LRDD  M V RL+
Sbjct:   81 VQVAEENFDGVEVIVYQPNQLEQTGELRRAIIYLHGGGWCLGSSRMGP--YDLLARHMVKELNAVIVAVEYRLAPAYHFPVQFEDVHRVVKYFLRNDVLKRYNINPERIAVSGDSAGGNLAAAV---------AQQLRKDPEQHIQLKAQALIYPVLQALDLKTPSYQQNQHMPILPRTLMVRFWSEY-------FTSDKSFLRAMMANTHNNHESAALLK-FVNWSSYLPDSYRQTYNYSAPPVLTGKGPVRSIGAHHLLADPRASPL-LVPDTALRFLPKAYVLTCEYDVLRDDGLMYVTRLR 365
[Close]
BLAST of Neutral cholesterol ester hydrolase 1 vs. Ensembl Zebrafish
Match: nceh1a (neutral cholesterol ester hydrolase 1a [Source:ZFIN;Acc:ZDB-GENE-040711-2])

HSP 1 Score: 135.191 bits (339), Expect = 7.603e-35
Identity = 99/297 (33.33%), Postives = 155/297 (52.19%), Query Frame = 1 
Query:  298 TNLTIKRK--LFDGVNVLVFSPIKRDRK-GPAIVYYHGGGWAVMNPEI--YSPFLANLARRLNTMIVAVDYRKAPEYPYPAPFNDALVATKYFLIN--CKEFDVDPNRIALMGDSAGGSLVVSVGYHLTAMKRASKIVHSPKVLISLNPVLQVVDFSTPSYRDNLHDPILVKARMARYYCIYAFGEQLSWTELRNCIEALISHRHLTVEAIQKVRGHVDWNNLLSGRGYDN-RPRSSFTQSVNQFSEKLSELVESVGFSPLSALNDSQLQILPPVYVYGSSKDPLRDDAKMLVARLK 1164
            TN  I+ +  LFDGV+V V+ P   + K   A+++ HGGGW++  P++  Y      ++  LN ++V VDYR AP+  +P  + + + A K+ L     K++ VDP R+A+ GDSAGG+L  +V   +      S      K+ + + PVLQ +DF+T SY+ N + PIL +  MAR++  Y   +     EL + I  + +H       + + R  +DW NLL      + +P    T S N  S+ +  L++S   SPL A  D  L++ P  Y+     D LRDD  M   RL+
Sbjct:   77 TNQEIQTEDVLFDGVHVRVYYPQGEEEKLRRAVMFIHGGGWSLGAPKLGSYDSLCRQMSADLNAVVVTVDYRMAPDVHFPVQYEECVQAAKHLLKPEVLKQYSVDPERVAVCGDSAGGNLAAAVAQRIGTENSTSAKF---KLQVLIYPVLQALDFNTASYQQNHNVPILYRRLMARFWLEYLGAD----PELAHSI-MMNNHTAQDQNLLSQNRAKLDWTNLLPKEIRKHFKPVFPVTGSPNILSD-VPGLLDSRA-SPLLA-EDEVLRMAPRAYIMTGEHDVLRDDGMMYARRLE 362
[Close]
BLAST of Neutral cholesterol ester hydrolase 1 vs. Ensembl Zebrafish
Match: nceh1a (neutral cholesterol ester hydrolase 1a [Source:ZFIN;Acc:ZDB-GENE-040711-2])

HSP 1 Score: 135.191 bits (339), Expect = 7.603e-35
Identity = 99/297 (33.33%), Postives = 155/297 (52.19%), Query Frame = 1 
Query:  298 TNLTIKRK--LFDGVNVLVFSPIKRDRK-GPAIVYYHGGGWAVMNPEI--YSPFLANLARRLNTMIVAVDYRKAPEYPYPAPFNDALVATKYFLIN--CKEFDVDPNRIALMGDSAGGSLVVSVGYHLTAMKRASKIVHSPKVLISLNPVLQVVDFSTPSYRDNLHDPILVKARMARYYCIYAFGEQLSWTELRNCIEALISHRHLTVEAIQKVRGHVDWNNLLSGRGYDN-RPRSSFTQSVNQFSEKLSELVESVGFSPLSALNDSQLQILPPVYVYGSSKDPLRDDAKMLVARLK 1164
            TN  I+ +  LFDGV+V V+ P   + K   A+++ HGGGW++  P++  Y      ++  LN ++V VDYR AP+  +P  + + + A K+ L     K++ VDP R+A+ GDSAGG+L  +V   +      S      K+ + + PVLQ +DF+T SY+ N + PIL +  MAR++  Y   +     EL + I  + +H       + + R  +DW NLL      + +P    T S N  S+ +  L++S   SPL A  D  L++ P  Y+     D LRDD  M   RL+
Sbjct:   77 TNQEIQTEDVLFDGVHVRVYYPQGEEEKLRRAVMFIHGGGWSLGAPKLGSYDSLCRQMSADLNAVVVTVDYRMAPDVHFPVQYEECVQAAKHLLKPEVLKQYSVDPERVAVCGDSAGGNLAAAVAQRIGTENSTSAKF---KLQVLIYPVLQALDFNTASYQQNHNVPILYRRLMARFWLEYLGAD----PELAHSI-MMNNHTAQDQNLLSQNRAKLDWTNLLPKEIRKHFKPVFPVTGSPNILSD-VPGLLDSRA-SPLLA-EDEVLRMAPRAYIMTGEHDVLRDDGMMYARRLE 362
[Close]
BLAST of Neutral cholesterol ester hydrolase 1 vs. Ensembl Zebrafish
Match: aadacl4 (arylacetamide deacetylase-like 4 [Source:ZFIN;Acc:ZDB-GENE-080919-2])

HSP 1 Score: 124.02 bits (310), Expect = 8.488e-31
Identity = 90/292 (30.82%), Postives = 140/292 (47.95%), Query Frame = 1 
Query:  301 NLTIKRKLFDGVNVLVFSPIKRD-RKGPAIVYYHGGGWAVMNPEIYSPFLANLARRLNTMIVAVDYRKAPEYPYPAPFNDALVATKYFL-INCKEFDVDPNRIALMGDSAGGSLVVSVGYHLTAMKRASKIVHSPKVLISLNPVLQVVDFSTPSYRDNLHDPILVKARMARYYCIYAFGEQLSWTELRNCIEALISHRHLTVEAIQKVRGHVDWNNLLSGRGYDNRPRSSFTQSVNQFSEKLSELVESVGFSPLSALNDSQLQILPPVYVYGSSKDPLRDDAKMLVARLKRL 1170
             L IK   F  V V V+ P      K   +VY+HGGGW     + Y     +++ + +T +V+V YR APE+ YPA  +D  VAT++FL I   +F VDP ++A+ GDSAG +L  ++   L+  K     + SP   + + P LQ+ DF  PSY+ N   PIL + R   Y+  Y  G         +  + ++  RH+  E   + +  +D N+L        R +   +         + + ++    SPL A  D  L ++PP +V     D LRDD  +   RL+ L
Sbjct:   97 GLRIKDLTFSTVPVRVYEPTAASGEKKRGLVYFHGGGWMFGCIDDYDEVCQHISLKSDTTVVSVGYRLAPEHRYPAHLDDCEVATRHFLSIAATDFGVDPCKVAVGGDSAGANLAAALCQRLS--KTQDGHLPSPCAQVLIYPALQMADFHLPSYQQNHSVPILFRGRTVFYFLQYLNGNT-------SVSQQILEGRHVPAELKLRYKKWLDPNSLPPQFIKQARCQQDLSSHDADVYHIVKQGLDP-EISPLLA-EDDVLCLVPPAFVLTCEFDVLRDDGFLYQKRLRDL 377
[Close]
BLAST of Neutral cholesterol ester hydrolase 1 vs. Ensembl Xenopus
Match: nceh1 (neutral cholesterol ester hydrolase 1 [Source:NCBI gene;Acc:493371])

HSP 1 Score: 154.066 bits (388), Expect = 1.324e-41
Identity = 105/319 (32.92%), Postives = 166/319 (52.04%), Query Frame = 1 
Query:  301 NLTIKRKLFDGVNVLVFSPIKRDRKG--PAIVYYHGGGWAVMNPEI--YSPFLANLARRLNTMIVAVDYRKAPEYPYPAPFNDALVATKYFLIN--CKEFDVDPNRIALMGDSAGGSLVVSVGYHLTAMKRASKIVHSPKVLISLNPVLQVVDFSTPSYRDNLHDPILVKARMARYYCIYAFGEQLSWTELRNCIEALISHRHLTVEAIQKV--RGHVDWNNLLSGRGYDNRPRSSFTQSVNQFSEKLSELVESVGFSPLSALNDSQLQILPPVYVYGSSKDPLRDDAKMLVARLKR--LRSFGDYWEFKCFHVCFLLG 1227
            +L +   +FDGV V +F P K   K    +IVY HGGGWA+ +  +  Y      ++  +N ++V+++YR  P+  +P   NDA+ ATKYFL      E+ VDP+RIA+ GDSAGG+L  +V   L      S +    K+   + PVLQV+DF+TPSY+ N+  PIL +  M +++  Y  G         +   +++ + H +V+  + V  R  ++WN+LL      N      +   ++   ++  L++ +  SPL A  +S LQ+LP  Y+     D LRDD  M   RL+   +    D++E   FH C L  
Sbjct:   80 HLKVTDTVFDGVEVRIFEPTKAFDKNLKKSIVYIHGGGWALGSARMRSYDSLCRKISEDVNAVVVSIEYRLVPDVHFPEQLNDAVAATKYFLHPEVLAEYSVDPSRIAVSGDSAGGNLAAAVCQQLAG---DSSVTTKVKLQALIYPVLQVLDFNTPSYQQNMDMPILSRFVMIKFWLDYLNGSH-------SFAHSMLVNNHTSVDLSETVTLRELLNWNSLLPSSFKKNYKPVLQSHGTHKIISEVPALLD-LRASPLIAKKES-LQLLPKTYILTCEHDVLRDDGTMYAKRLEEAGVDVTHDHYE-DGFHGCMLFA 385
[Close]
BLAST of Neutral cholesterol ester hydrolase 1 vs. Ensembl Xenopus
Match: cog6 (component of oligomeric golgi complex 6 [Source:Xenbase;Acc:XB-GENE-944762])

HSP 1 Score: 137.502 bits (345), Expect = 2.000e-35
Identity = 98/299 (32.78%), Postives = 150/299 (50.17%), Query Frame = 1 
Query:  286 MSDKTNLTIKRKLFDGVNVLVF---SPIKRDRKGPAIVYYHGGGWAVMNPEIYSPFLANLARRLNTMIVAVDYRKAPEYPYPAPFNDALVATKYFLINCKEFDVDPNRIALMGDSAGGSLVVSVGYHLTAMKRASKIVHSPKVLISLNPVLQVVDFSTPSYRDNLHDPILVKARMARYYCIYAFGEQLSWTELRNCIEALISHRHLTVEAIQKVRGHVDWNNL---LSGRGYDNRPRSSFTQSVNQFSEKLSELVESVGFSPLSALNDSQLQILPPVYVYGSSKDPLRDDAKMLVARLK 1164
            + +   L IK   F+ V V V+   SP    RKG  +++ HGGGW   + + Y      +++   T++V+V YR  PE+ YPA F D L AT +FL   +E+ VDP+ + + GDSAGG+L  +V   L       K    P   + + P +Q++DF  PSY+ N   PIL + R A +Y +    + L      N +E ++   H+ VE   K R  +   N+      RGY  R  SS T+ V    E++  ++E+   SPL A  DS +++ P  Y+     D LRDD  +   RL+
Sbjct:   87 LGEDPKLFIKDHQFEKVPVRVYQPRSPSAGGRKG--VMFLHGGGWMFGSIDTYDILCRYISKETETVVVSVGYRLTPEHRYPAGFEDCLNATVHFLETAQEYGVDPSSVIIAGDSAGGNLTAAVCQSLVNKTNLPK----PLAQVLIYPAVQMIDFDLPSYQQNRAVPILYRER-AVFYMLNYICDDL------NVLEEMLDGDHIPVETKMKYRKWLSAENIPDEFKARGYKPRIMSSQTEEV---IEEVKNVLEAT-CSPLLA-EDSVIRLQPKAYILTCEFDVLRDDGLLYKKRLE 367
[Close]
BLAST of Neutral cholesterol ester hydrolase 1 vs. Ensembl Xenopus
Match: meiob (meiosis specific with OB domains [Source:Xenbase;Acc:XB-GENE-987591])

HSP 1 Score: 136.732 bits (343), Expect = 2.700e-35
Identity = 101/306 (33.01%), Postives = 158/306 (51.63%), Query Frame = 1 
Query:  301 NLTIKRKLFDGVNVLVFSP---IKRDRKGPAIVYYHGGGW----AVMNPEIYSPFLANLARRLNTMIVAVDYRKAPEYPYPAPFNDALVATKYFLIN--CKEFDVDPNRIALMGDSAGGSLVVSVGYHLTAMKRASKIVHSPKVLISLN------PVLQVVDFSTPSYRDNLHDPILVKARMARYYCIYAFGEQLSWTELRNCIEALISHRHLTVEAIQKVRGHVDWNNLLSGRGYDNRP--RSSFTQSVNQFSEKLSELVESVGFSPLSALNDSQLQILPPVYVYGSSKDPLRDDAKMLVARLKR 1167
            N+++    F  V V +F P   +   R+  A++Y HGGGW    + M P  Y       A +L+ ++V++DYR AP + +P  F+D    TKYFL     +++ VDP+R+A+ GDSAGG+L  ++         A ++++ P+V + L       PVLQ +D +TPSY+DN   P+L K+ M R++  Y        T  R   EA+  ++H+  EA   +R  V+W+ LL           +S F  S   F  K   ++++   SPL A  D +L+ LP  Y+     D LRDD  M  ARL++
Sbjct:   78 NVSVTDTSFSNVPVRLFIPKAAVTEQRR--AVIYIHGGGWCLGSSAMKP--YDLLGRYTALQLDAVVVSIDYRLAPAFHFPTQFDDVYAVTKYFLDKDILQKYSVDPSRVAVAGDSAGGNLAAAI---------AQQLLNDPEVKVKLKIQALIYPVLQDIDMNTPSYQDNGDMPVLSKSLMVRFWSEYI-------TIDRTLGEAMWHNKHIPAEAEHVLR-FVNWSTLLPDNLKKQHVYLKSEFGSS--GFVNKYPAILDAKA-SPLLA-EDEKLKGLPTAYIITCMYDVLRDDGFMYAARLRK 358
[Close]
BLAST of Neutral cholesterol ester hydrolase 1 vs. Ensembl Xenopus
Match: ENSXETT00000037153.1 (pep primary_assembly:Xenopus_tropicalis_v9.1:KV464221.1:3349:4392:-1 gene:ENSXETG00000015307.1 transcript:ENSXETT00000037153.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 106.686 bits (265), Expect = 1.640e-25
Identity = 77/227 (33.92%), Postives = 113/227 (49.78%), Query Frame = 1 
Query:  493 YRKAPEYPYPAPFNDALVATKYFLINCKEFDVDPNRIALMGDSAGGSLVVSVGYHLTAMKRASKIVHSPKVLISLNPVLQVVDFSTPSYRDNLHDPILVKARMARYYCIYAFGEQLSWTELRNCIEALISHRHLTVEAIQKVRGHVDWNNL---LSGRGYDNRPRSSFTQSVNQFSEKLSELVESVGFSPLSALNDSQLQILPPVYVYGSSKDPLRDDAKMLVARLK 1164
            YR  PE+ YPA F D L AT +FL   +E+ VDP+ + + GDSAGG+L  +V   L       K    P   + + P +Q++DF  PSY+ N   PIL + R A +Y +    + L      N +E ++   H+ VE   K R  +   N+      RGY  R  SS T+ V    E++  ++E+   SPL A  DS + + P  Y+     D LRDD  +   RL+
Sbjct:   10 YRLTPEHRYPAGFEDCLNATVHFLETAQEYGVDPSSVIIAGDSAGGNLTAAVCQSLVNKTNLPK----PLAQVLIYPAVQMIDFDLPSYQQNRAVPILYRER-AVFYMLNYICDDL------NVLEEMLDGDHIPVETKMKYRKWLSAENIPDEFKARGYKPRIMSSQTEEV---IEEVKNVLEATC-SPLLA-EDSVIHLQPKAYILTCEFDVLRDDGLLYKKRLE 220
[Close]
BLAST of Neutral cholesterol ester hydrolase 1 vs. Ensembl Xenopus
Match: ENSXETT00000037158.1 (pep primary_assembly:Xenopus_tropicalis_v9.1:KV464221.1:2919:4258:-1 gene:ENSXETG00000015307.1 transcript:ENSXETT00000037158.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 106.301 bits (264), Expect = 3.618e-25
Identity = 77/227 (33.92%), Postives = 113/227 (49.78%), Query Frame = 1 
Query:  493 YRKAPEYPYPAPFNDALVATKYFLINCKEFDVDPNRIALMGDSAGGSLVVSVGYHLTAMKRASKIVHSPKVLISLNPVLQVVDFSTPSYRDNLHDPILVKARMARYYCIYAFGEQLSWTELRNCIEALISHRHLTVEAIQKVRGHVDWNNL---LSGRGYDNRPRSSFTQSVNQFSEKLSELVESVGFSPLSALNDSQLQILPPVYVYGSSKDPLRDDAKMLVARLK 1164
            YR  PE+ YPA F D L AT +FL   +E+ VDP+ + + GDSAGG+L  +V   L       K    P   + + P +Q++DF  PSY+ N   PIL + R A +Y +    + L      N +E ++   H+ VE   K R  +   N+      RGY  R  SS T+ V    E++  ++E+   SPL A  DS + + P  Y+     D LRDD  +   RL+
Sbjct:   33 YRLTPEHRYPAGFEDCLNATVHFLETAQEYGVDPSSVIIAGDSAGGNLTAAVCQSLVNKTNLPK----PLAQVLIYPAVQMIDFDLPSYQQNRAVPILYRER-AVFYMLNYICDDL------NVLEEMLDGDHIPVETKMKYRKWLSAENIPDEFKARGYKPRIMSSQTEEV---IEEVKNVLEAT-CSPLLA-EDSVIHLQPKAYILTCEFDVLRDDGLLYKKRLE 243
[Close]
BLAST of Neutral cholesterol ester hydrolase 1 vs. Ensembl Mouse
Match: Nceh1 (neutral cholesterol ester hydrolase 1 [Source:MGI Symbol;Acc:MGI:2443191])

HSP 1 Score: 152.14 bits (383), Expect = 5.146e-41
Identity = 113/356 (31.74%), Postives = 179/356 (50.28%), Query Frame = 1 
Query:  259 SGLGKLNYYMSDKTNLTIKRKLFDGVNVLVF--SPIKRDRKGPAIVYYHGGGWAVMNPEI--YSPFLANLARRLNTMIVAVDYRKAPEYPYPAPFNDALVATKYFLIN--CKEFDVDPNRIALMGDSAGGSLVVSVGYHLTAMKRASKIVHSPKVLISLNPVLQVVDFSTPSYRDNLHDPILVKARMARYYCIYAFGEQLSWTELRNCIEALI--SHRHLTVEAIQKVRGHVDWNNLLSGRGYDNRPRSSFTQSVNQFSEKLSELVESVGFSPLSALNDSQLQILPPVYVYGSSKDPLRDDAKMLVARLKRLRSFG-----DYWEFKCFHVCFLLG------RIGVKDEETSLKEL 1269
            +  GK +   S K  +T     FDGV V VF  SP   +    +++Y HGGGWA+ + +I  Y      +A  LN +IV+++YR  P+  +P   +D + ATKYFL      ++ VDP R+ + GDSAGG+L  ++G   T +   + + +  K+   + PVLQ +DF+TPSY+ +++ PIL +  M RY+  Y  G         + +EA+I  +H  L VE    +R  +DW +LL      N      T    +  +++ +L+++   SPL A  +  L+ LP  Y+     D LRDD  M     KRL S G     D++E   FH C +         +G++   + +K L
Sbjct:   67 TSFGKQSARSSPKVKVTDTD--FDGVEVRVFEGSPKPEEPLRRSVIYIHGGGWALASAKISYYDQLCTTMAEELNAVIVSIEYRLVPQVYFPEQIHDVIRATKYFLQPEVLDKYKVDPGRVGISGDSAGGNLAAALGQQFTYV---ASLKNKLKLQALVYPVLQALDFNTPSYQQSMNTPILPRHVMVRYWLDYFKGN-------YDFVEAMIVNNHTSLDVERAAALRARLDWTSLLPSSIKKNYKPIMQTTGNARIVQEIPQLLDAAA-SPLIAEQEV-LEALPKTYILTCEHDVLRDDGIMYA---KRLESAGVNVTLDHFE-DGFHGCMIFTSWPTNFSVGIRTRNSYIKWL 404
[Close]
BLAST of Neutral cholesterol ester hydrolase 1 vs. Ensembl Mouse
Match: Aadacl2 (arylacetamide deacetylase like 2 [Source:MGI Symbol;Acc:MGI:3646333])

HSP 1 Score: 122.094 bits (305), Expect = 3.372e-30
Identity = 98/327 (29.97%), Postives = 170/327 (51.99%), Query Frame = 1 
Query:  244 YRCFESGLGKLNYY--MSDKTNLTIKRKLFDGVNVLVFSPIKRDRKGP--AIVYYHGGGWAVMNPEIYSPFLAN--LARRLNTMIVAVDYRKAPEYPYPAPFNDALVATKYFLIN--CKEFDVDPNRIALMGDSAGGSLVVSVGYHLTAMKRASKIVHSPKVLISLNPVLQVVDFSTPSYRDNLHDPILVKARMARYYCIYAFGEQLSWTELRNCIEALISHRHLTVEAIQKVRGHVDWNNLLSGRGYDNRPRSSFTQSVNQFSEKLSELVESVGFSPLSALNDSQLQILPPVYVYGSSKDPLRDDAKMLVARLKR--LRSFGDYWE 1194
            Y  F S +  L+Y   +SD+ ++T+    F  + V ++ P KR  + P  A++Y+HGGG+   + +  +    N   A +L+ ++V +DYR AP++ +PA F D + A K+FL +    ++ VDP RIA+ GDS+GG+L  +V      ++   ++ H  K+   L P LQV+D   PS+R+N H  +L +    +   ++       +T+     +A+  ++H+  E+    R  V+W+ LL  +   +   +      + FS  L  L++     PL A +D  LQ LP  Y+     D LRDD  M V+RL++  ++ F D+ E
Sbjct:   58 YEEFISMIINLDYTQPLSDE-HITVTDTAFVDIPVRLYLP-KRKSEAPRRAVIYFHGGGFCFGSFKQRAFDFLNRWTANKLDAVVVGIDYRLAPQHHFPAQFEDGITAVKFFLQDKILTKYGVDPTRIAVSGDSSGGTLAAAVT---QQVQIDPEVKHKLKLQALLYPGLQVIDTHLPSHRENEHGIVLTRDIAIKLVSLF-------FTKDEALPQAMRKNQHMPPESRHLFR-FVNWSTLLPDKFRKDHVYTEPVLGRSAFS--LPALMDHRAL-PLLA-SDDHLQHLPQTYILTCQHDVLRDDGIMYVSRLQKVGVQVFHDHVE 367
[Close]
BLAST of Neutral cholesterol ester hydrolase 1 vs. Ensembl Mouse
Match: Aadac (arylacetamide deacetylase [Source:MGI Symbol;Acc:MGI:1915008])

HSP 1 Score: 119.398 bits (298), Expect = 3.686e-29
Identity = 86/305 (28.20%), Postives = 153/305 (50.16%), Query Frame = 1 
Query:  289 SDKTNLTIKRKLFDGVNVLVFSPIKRD---RKGPAIVYYHGGGWAVMNPE--IYSPFLANLARRLNTMIVAVDYRKAPEYPYPAPFNDALVATKYFLIN--CKEFDVDPNRIALMGDSAGGSLVVSVGYHLTAMKRASKIVHSPKVLISLN------PVLQVVDFSTPSYRDNLHDPILVKARMARYYCIYAFGEQLSWTELRNCIEALISHRHLTVEAIQKVRGHVDWNNLLSGRGYDNRPRSSFTQSVNQFSEKLSELVESVGFSPLSALNDSQLQILPPVYVYGSSKDPLRDDAKMLVARLK 1164
            +   ++T+    FD V V ++ P ++    R+G  + Y HGGGW + +     Y       A +L+ ++V+ DY  AP++ +P  F D   + ++FL     +++ VDP R+ + GDSAGG+L  +V           +++  P V I L       P LQ +D + PS ++  H P+L ++ M R++  Y       +T  R   +A++ ++H+ +E+   ++  V+W++LL  R   +    + T   ++ ++K    ++ V   PL A ND+ L  LP  Y+     D LRDD  M V RL+
Sbjct:   73 TSDEHVTVMETAFDSVPVRIYIPKRKSMALRRG--LFYIHGGGWCLGSAAHFSYDTLSRWTAHKLDAVVVSTDYGLAPKHHFPRQFEDVYRSLRWFLQEDVLEKYGVDPRRVGVSGDSAGGNLAAAV---------TQQLIQDPDVKIKLKVQALIYPALQALDTNVPSQQEGSHFPVLTRSLMVRFWSEY-------FTTDRGLEKAMLLNQHVPMESSHLLQ-FVNWSSLLPERYKKSPVYKNPTPGSSELAQKYPGFID-VKACPLLA-NDNILHHLPKTYIITCQYDVLRDDGLMYVKRLQ 356
[Close]
BLAST of Neutral cholesterol ester hydrolase 1 vs. Ensembl Mouse
Match: Aadacl2fm3 (AADACL2 family member 3 [Source:MGI Symbol;Acc:MGI:3643798])

HSP 1 Score: 115.546 bits (288), Expect = 8.497e-28
Identity = 88/297 (29.63%), Postives = 153/297 (51.52%), Query Frame = 1 
Query:  301 NLTIKRKLFDGVNVLVFSPIKR-DRKGPAIVYYHGGGWAVMNPEI--YSPFLANLARRLNTMIVAVDYRKAPEYPYPAPFNDALVATKYFLIN--CKEFDVDPNRIALMGDSAGGSLVVSVGYHLTAMKRASKIVHSPKVLISLNPVLQVVDFSTPSYRDNLHDPILVKARMARYYCIY-AFGEQLSWTELRNCIEALISHRHLTVEAIQKVRGHVDWNNLLSGRGYDNRPRSSFTQSV-NQFSEKLSELVESVGFSPLSALNDSQLQILPPVYVYGSSKDPLRDDAKMLVARLKRL 1170
            N+T+    F  + V ++ P ++ +++ PA+++ HGG + + + ++  Y       A +L+ +++A DYR AP++ +PA   D +   K+FL +    ++ VDP RI + GDS+GG+L  +V      ++   +  +  K    L P LQ +D   PS+R+  H P L +    R  C+Y +  ++L  T LRN         H+  E+ + +   V+W++ L  +   N     +T+ V    +     LV+S   SPL  +NDSQLQ LP  Y+     D LRDD  + V RL+++
Sbjct:   78 NITVIDTDFSDIPVRLYLPKRKSEKQRPAVIFIHGGAYILGSFKMLPYDSVNRWTANKLDAVVMAPDYRLAPQHLFPAALEDCIFVIKFFLQDKVLAKYGVDPTRICISGDSSGGTLAATVT---QLLQDDPEYKNKIKAQTLLYPALQALDTLMPSHREYKHGPFLTRKVAIRLTCLYLSEDKELPKTILRNA--------HVPQES-RHLFKFVNWSDFLPEKYKKNH---VYTEPVLGNLNASHPGLVDSRA-SPL-LVNDSQLQKLPLTYILTCEHDILRDDGLIYVTRLRKV 357
[Close]
BLAST of Neutral cholesterol ester hydrolase 1 vs. Ensembl Mouse
Match: Aadacl2fm2 (AADACL2 family member 2 [Source:MGI Symbol;Acc:MGI:3779495])

HSP 1 Score: 114.775 bits (286), Expect = 1.266e-27
Identity = 87/305 (28.52%), Postives = 155/305 (50.82%), Query Frame = 1 
Query:  271 KLNYYMSDKTNLTIKRKLFDGVNVLVFSPIKR-DRKGPAIVYYHGGGWAVMNPEI--YSPFLANLARRLNTMIVAVDYRKAPEYPYPAPFNDALVATKYFLINC--KEFDVDPNRIALMGDSAGGSLVVSVGYHLTAMKRASKIVHSPKVLISLNPVLQVVDFSTPSYRDNLHDPILVKARMARYYCIYAFGEQLSWTELRNCIEALISHRHLTVEAIQKVRGHVDWNNLLSGRGYDNRPRSSFTQSVNQFSEKLSELVESVGFSPLSALNDSQLQILPPVYVYGSSKDPLRDDAKMLVARLKRL 1170
            +L   +SD+ N+T+    F  + V ++ P ++ +++ PA+++ HGG + + + ++  Y       A +L+ ++V +DYR AP+YP+PA   D ++  KYFL +   K++ VDP RI + GDS GG+L  +    +  ++   +     K    L P LQ +D   PS+R N H P L +    +   +Y        TE    ++A+  + H+  +  + +   V+W++ L  +   N   +  T  + + +     L++S   SPL  +NDSQLQ LP  Y+     D LRDD  +   RL+ +
Sbjct:   69 QLTKPVSDE-NITVIDTDFSDIPVRLYLPKRKSEKQRPAVIFIHGGAFTLGSCKMLPYDYLNRWTANKLDAVVVGIDYRLAPQYPFPAALEDCVLVIKYFLQDTILKKYGVDPTRICISGDSCGGTLATTA---IQLLQNNPEHKDKIKAQALLYPGLQFIDTLMPSHRINEHGPFLSREIAIKLAYLYV-------TEDTALVQAMQRNEHMP-KGSRHLFKFVNWSDFLPEKYKKNYVYTEPT--LGKLNVFYPALLDS-RLSPL-LVNDSQLQSLPLTYILTCEHDILRDDGLIYSTRLRNV 357
[Close]
BLAST of Neutral cholesterol ester hydrolase 1 vs. UniProt/SwissProt
Match: sp|Q6PIU2|NCEH1_HUMAN (Neutral cholesterol ester hydrolase 1 OS=Homo sapiens OX=9606 GN=NCEH1 PE=1 SV=3)

HSP 1 Score: 152.525 bits (384), Expect = 2.677e-40
Identity = 115/359 (32.03%), Postives = 183/359 (50.97%), Query Frame = 1 
Query:  265 LGKLNYYMSDKTNLTIKRKLFDGVNVLVFS-------PIKRDRKGPAIVYYHGGGWAVMNPEI--YSPFLANLARRLNTMIVAVDYRKAPEYPYPAPFNDALVATKYFLIN--CKEFDVDPNRIALMGDSAGGSLVVSVGYHLTAMKRASKIVHSPKVLISLNPVLQVVDFSTPSYRDNLHDPILVKARMARYYCIYAFGEQLSWTELRNCIEALI--SHRHLTVEAIQKVRGHVDWNNLLSGRGYDNRPRSSFTQSVNQFSEKLSELVESVGFSPLSALNDSQLQILPPVYVYGSSKDPLRDDAKMLVARLKRLRSFG-----DYWEFKCFHVCFLLG------RIGVKDEETSLKEL 1269
             GK + + S +  +T     FDGV V VF        P+KR     ++VY HGGGWA+ + +I  Y      +A  LN +IV+++YR  P+  +P   +D + ATKYFL     +++ VDP RI + GDSAGG+L  ++G   T   + + + +  K+   + PVLQ +DF+TPSY+ N++ PIL +  M +Y+  Y  G         + ++A+I  +H  L VE    VR  ++W +LL      N      T    +  ++L +L+++   +PL A + + LQ+LP  Y+     D LRDD  M     KRL S G     D++E   FH C +         +G++   + +K L
Sbjct:   69 FGKKSAWSSAQVKVTDTD--FDGVEVRVFEGPPKPEEPLKR-----SVVYIHGGGWALASAKIRYYDELCTAMAEELNAVIVSIEYRLVPKVYFPEQIHDVVRATKYFLKPEVLQKYMVDPGRICISGDSAGGNLAAALGQQFT---QDASLKNKLKLQALIYPVLQALDFNTPSYQQNVNTPILPRYVMVKYWVDYFKGN-------YDFVQAMIVNNHTSLDVEEAAAVRARLNWTSLLPASFTKNYKPVVQTTGNARIVQELPQLLDARS-APLIA-DQAVLQLLPKTYILTCEHDVLRDDGIMYA---KRLESAGVEVTLDHFE-DGFHGCMIFTSWPTNFSVGIRTRNSYIKWL 404
[Close]
BLAST of Neutral cholesterol ester hydrolase 1 vs. UniProt/SwissProt
Match: sp|Q8BLF1|NCEH1_MOUSE (Neutral cholesterol ester hydrolase 1 OS=Mus musculus OX=10090 GN=Nceh1 PE=1 SV=1)

HSP 1 Score: 152.14 bits (383), Expect = 3.600e-40
Identity = 113/356 (31.74%), Postives = 179/356 (50.28%), Query Frame = 1 
Query:  259 SGLGKLNYYMSDKTNLTIKRKLFDGVNVLVF--SPIKRDRKGPAIVYYHGGGWAVMNPEI--YSPFLANLARRLNTMIVAVDYRKAPEYPYPAPFNDALVATKYFLIN--CKEFDVDPNRIALMGDSAGGSLVVSVGYHLTAMKRASKIVHSPKVLISLNPVLQVVDFSTPSYRDNLHDPILVKARMARYYCIYAFGEQLSWTELRNCIEALI--SHRHLTVEAIQKVRGHVDWNNLLSGRGYDNRPRSSFTQSVNQFSEKLSELVESVGFSPLSALNDSQLQILPPVYVYGSSKDPLRDDAKMLVARLKRLRSFG-----DYWEFKCFHVCFLLG------RIGVKDEETSLKEL 1269
            +  GK +   S K  +T     FDGV V VF  SP   +    +++Y HGGGWA+ + +I  Y      +A  LN +IV+++YR  P+  +P   +D + ATKYFL      ++ VDP R+ + GDSAGG+L  ++G   T +   + + +  K+   + PVLQ +DF+TPSY+ +++ PIL +  M RY+  Y  G         + +EA+I  +H  L VE    +R  +DW +LL      N      T    +  +++ +L+++   SPL A  +  L+ LP  Y+     D LRDD  M     KRL S G     D++E   FH C +         +G++   + +K L
Sbjct:   67 TSFGKQSARSSPKVKVTDTD--FDGVEVRVFEGSPKPEEPLRRSVIYIHGGGWALASAKISYYDQLCTTMAEELNAVIVSIEYRLVPQVYFPEQIHDVIRATKYFLQPEVLDKYKVDPGRVGISGDSAGGNLAAALGQQFTYV---ASLKNKLKLQALVYPVLQALDFNTPSYQQSMNTPILPRHVMVRYWLDYFKGN-------YDFVEAMIVNNHTSLDVERAAALRARLDWTSLLPSSIKKNYKPIMQTTGNARIVQEIPQLLDAAA-SPLIAEQEV-LEALPKTYILTCEHDVLRDDGIMYA---KRLESAGVNVTLDHFE-DGFHGCMIFTSWPTNFSVGIRTRNSYIKWL 404
[Close]
BLAST of Neutral cholesterol ester hydrolase 1 vs. UniProt/SwissProt
Match: sp|Q5R8Y5|NCEH1_PONAB (Neutral cholesterol ester hydrolase 1 OS=Pongo abelii OX=9601 GN=NCEH1 PE=2 SV=1)

HSP 1 Score: 151.754 bits (382), Expect = 5.359e-40
Identity = 110/339 (32.45%), Postives = 175/339 (51.62%), Query Frame = 1 
Query:  325 FDGVNVLVFS-------PIKRDRKGPAIVYYHGGGWAVMNPEI--YSPFLANLARRLNTMIVAVDYRKAPEYPYPAPFNDALVATKYFLIN--CKEFDVDPNRIALMGDSAGGSLVVSVGYHLTAMKRASKIVHSPKVLISLNPVLQVVDFSTPSYRDNLHDPILVKARMARYYCIYAFGEQLSWTELRNCIEALI--SHRHLTVEAIQKVRGHVDWNNLLSGRGYDNRPRSSFTQSVNQFSEKLSELVESVGFSPLSALNDSQLQILPPVYVYGSSKDPLRDDAKMLVARLKRLRSFG-----DYWEFKCFHVCFLLG------RIGVKDEETSLKEL 1269
            FDGV V VF        P+KR     ++VY HGGGWA+ + +I  Y      +A  LN +IV+++YR  P+  +P   +D + ATKYFL     +++ VDP RI + GDSAGGSL  ++G   T   + + + +  K+   + PVLQ +DF+TPSY+ N++ PIL +  M +Y+  Y  G         + ++A+I  +H  L VE    +R  ++W +LL      N      T    +  ++L +L+++   +PL A + + LQ+LP  Y+     D LRDD  M     KRL + G     D++E   FH C +         +G++   + +K L
Sbjct:   87 FDGVEVRVFEGPPKPEEPLKR-----SVVYIHGGGWALASAKIRYYDELCTAMAEELNAVIVSIEYRLVPKVYFPEQIHDVVRATKYFLKPEVLQKYMVDPGRICISGDSAGGSLAAALGQQFT---QDASLKNKLKLQALIYPVLQALDFNTPSYQQNVNTPILPRYVMVKYWVDYFKGN-------YDFVQAMIVNNHTSLDVEEAAALRARLNWTSLLPASFTKNYKPVVQTTGNARIVQELPQLLDARS-APLIA-DQAVLQLLPKTYILTCEHDVLRDDGIMYA---KRLETAGVEVTLDHFE-DGFHGCMIFTSRPTNFSVGIRTRNSYIKWL 404
[Close]
BLAST of Neutral cholesterol ester hydrolase 1 vs. UniProt/SwissProt
Match: sp|B2GV54|NCEH1_RAT (Neutral cholesterol ester hydrolase 1 OS=Rattus norvegicus OX=10116 GN=Nceh1 PE=1 SV=1)

HSP 1 Score: 149.828 bits (377), Expect = 2.765e-39
Identity = 111/334 (33.23%), Postives = 171/334 (51.20%), Query Frame = 1 
Query:  325 FDGVNVLVFS-PIKRDRK-GPAIVYYHGGGWAVMNPEI--YSPFLANLARRLNTMIVAVDYRKAPEYPYPAPFNDALVATKYFLIN--CKEFDVDPNRIALMGDSAGGSLVVSVGYHLTAMKRASKIVHSPKVLISLNPVLQVVDFSTPSYRDNLHDPILVKARMARYYCIYAFGEQLSWTELRNCIEALI--SHRHLTVEAIQKVRGHVDWNNLLSGRGYDNRPRSSFTQSVNQFSEKLSELVESVGFSPLSALNDSQLQILPPVYVYGSSKDPLRDDAKMLVARLKRLRSFG-----DYWEFKCFHVCFLLG------RIGVKDEETSLKEL 1269
            FDGV V VF  P K D     ++VY HGGGWA+ + +I  Y      +A  LN +IV+++YR  P+  +P   +D + ATKYFL      ++ VDP R+ + GDSAGG+L  ++G   T ++    + +  K+   + PVLQ +DF+TPSY+ +++ PIL +  M RY+  Y  G         + +EA+I  +H  L VE    +R  +DW +LL      N      T    +  +++ +L+++   SPL A  +  LQ LP  Y+     D LRDD  M     KRL S G     D++E   FH C +         +G++  ++  K L
Sbjct:   87 FDGVEVRVFEGPPKPDEPLRRSVVYIHGGGWALASAKISYYDQLCTAMAEELNAVIVSIEYRLVPQVYFPEQIHDVIRATKYFLQPEVLDKYKVDPGRVGVSGDSAGGNLAAALGQQFTYVE---SLKNKLKLQALIYPVLQALDFNTPSYQQSMNTPILPRHVMVRYWVDYFKGN-------YDFVEAMIVNNHTSLDVERAAALRARLDWTSLLPSSIKKNYKPVLQTIGDARIVKEIPQLLDAAA-SPLIAEQEV-LQALPKTYILTCEHDVLRDDGIMYA---KRLESAGVNVTLDHFE-DGFHGCMIFTSWPTNFSVGIRTRDSYFKWL 404
[Close]
BLAST of Neutral cholesterol ester hydrolase 1 vs. UniProt/SwissProt
Match: sp|Q0P5B7|AAAD_BOVIN (Arylacetamide deacetylase OS=Bos taurus OX=9913 GN=AADAC PE=2 SV=1)

HSP 1 Score: 148.673 bits (374), Expect = 7.123e-39
Identity = 106/335 (31.64%), Postives = 178/335 (53.13%), Query Frame = 1 
Query:  289 SDKTNLTIKRKLFDGVNVLVFSPIKRD---RKGPAIVYYHGGGWAVMNPEIYSPFLAN--LARRLNTMIVAVDYRKAPEYPYPAPFNDALVATKYFL--INCKEFDVDPNRIALMGDSAGGSLVVSVGYHLTAMKRASKIVHSPKVLISLN------PVLQVVDFSTPSYRDNLHDPILVKARMARYYCIYAFGEQLSWTELRNCIEALISHRHLTVEAIQKVRGHVDWNNLLSGRGYDNRPRSSFTQSVNQFSEKLSELVESVGFSPLSALNDSQLQILPPVYVYGSSKDPLRDDAKMLVARLKR--LRSFGDYWEFKCFH--VCFLLGRIGVK 1242
            +   N+ +K   F+ + V ++ P ++    R+G  + Y HGGGW   + + YS  L +   A RL+ ++++ +YR AP+Y +P  F D   A K+FL   N + + VDP RI + GDSAGG+L  +V         A +++  P V I L       P LQ  DF  PSYR+N H P+L K+ M R++  Y       +T  R+  +A++S++H+ +E+    +  V+W++LL  +        + T   ++ ++K   +++ V  SPL A +DS+L+ LP  YV     D LRDD  M V RL++  ++   ++ E   FH  + FL  ++G +
Sbjct:   74 TSDENIIVKDTTFNDIPVRIYVPQQKTKSLRRG--LFYIHGGGWCFGSNDYYSYDLLSRWTAERLDAVVISTNYRLAPKYHFPVQFEDVYTALKWFLDPQNLESYGVDPGRIGISGDSAGGNLAAAV---------AQQLLEDPDVKIKLKVQTLIYPALQNFDFDLPSYRENAHYPVLSKSLMVRFWSEY-------FTTDRSLKKAMLSNQHIPLESSNLFK-FVNWSSLLPEKFKKGHIYKTPTHGSSELAKKYPGILD-VKASPLLA-DDSKLRGLPLTYVITCQYDVLRDDGLMYVTRLQKSGVQVIHNHVE-GAFHGTLAFLFTKVGYR 386
[Close]
BLAST of Neutral cholesterol ester hydrolase 1 vs. TrEMBL
Match: A0A210PFU6 (Arylacetamide deacetylase OS=Mizuhopecten yessoensis OX=6573 GN=KP79_PYT19485 PE=4 SV=1)

HSP 1 Score: 186.422 bits (472), Expect = 1.871e-50
Identity = 114/296 (38.51%), Postives = 166/296 (56.08%), Query Frame = 1 
Query:  298 TNLTIKRKLFDGVNVLVFSP--IKRDRKGPAIVYYHGGGWAVMNPEIYSPFLANLARRLNTMIVAVDYRKAPEYPYPAPFNDALVATKYFLINCKEFDVDPNRIALMGDSAGGSLVVSVGYHLTAMKRASKIVHSPKVLISLNPVLQVVDFSTPSYRDNLHDPILVK-ARMARYYCIYAFGEQLSWTELRNCIEALISHRHLTVEAIQKVRGHVDWNNLLSG-RGYDNRPRSSFTQSVNQ-FSEKLSELVESVGFSPLSALNDSQLQILPPVYVYGSSKDPLRDDAKMLVARLKRL 1170
            + + I  +LFDGV V +F P  +   +  PA+V+YHGGGW + + E YS F   L+  L  ++ +V+YR APE+ +P PF D + ATKYF+ N K+F VD +RIAL GDSAGG+L ++VG  LT  ++       P++L    P LQ+VDF TPSY      P L++ ARM ++Y  Y FG         N +E  + + H+T +  ++V   V+   L    + +  RP     +SV+Q  +EK+ +L  +V   PL  L+D  L  LP  Y+     DPLRDD  ML  R K +
Sbjct:   82 SEVKITEELFDGVKVRLFVPRDLTDKQDLPALVFYHGGGWIIGSVEQYSLFTKRLSTSLPVIVASVEYRLAPEHLFPIPFEDCVTATKYFMKNAKKFGVDASRIALSGDSAGGNLAMAVGIKLTQERQP------PRLLGLFYPALQIVDFKTPSYNTYNSAPYLLRSARMIKFYLRYIFGND-------NDLEKFLKNEHITEKMRREVNSKVNVEFLPEKYQKFKTRPEDP--KSVDQSLAEKVEKLATNVYMCPL-MLDDQMLSQLPKTYLMTCEYDPLRDDGLMLAKRWKDM 361
[Close]
BLAST of Neutral cholesterol ester hydrolase 1 vs. TrEMBL
Match: A0A210PF69 (Arylacetamide deacetylase OS=Mizuhopecten yessoensis OX=6573 GN=KP79_PYT19124 PE=4 SV=1)

HSP 1 Score: 186.037 bits (471), Expect = 2.050e-50
Identity = 113/302 (37.42%), Postives = 166/302 (54.97%), Query Frame = 1 
Query:  274 LNYYMSDKTNLTIKRKLFDGVNVLVFSPIKRDRKGP--AIVYYHGGGWAVMNPEIYSPFLANLARRLNTMIVAVDYRKAPEYPYPAPFNDALVATKYFLINCKEFDVDPNRIALMGDSAGGSLVVSVGYHLTAMKRASKIVHSPKVLISLNPVLQVVDFSTPSYRDNLHDP-ILVKARMARYYCIYAFGEQLSWTELRNCIEALISHRHLTVEAIQKVRGHVDWNNLLSGRGYDNRPRSSFTQSVNQFSEKLSELVESVGFSPLSALNDSQLQILPPVYVYGSSKDPLRDDAKMLVARLKRL 1170
            LN  +SD  N+ +  +LFDGV V ++ P  +  K P   I+Y HGGGW + + ++Y     NLA  L+ ++ +VDYR APEYP+P PF D L ATKYF++N ++F VD +RIA+ GDSAGG+L ++VG  LT      K    P++L  + P LQ++DF+TPSY      P +L K RM  +Y  YAFG +       N IE  + +RH++    + +   V  +  L    Y      + T      + K+ + + ++   PL  L+D +L  LP  Y+     DPLRDD  ML  R K +
Sbjct:   76 LNIGVSDD-NVQVSEELFDGVKVRLYVPRDQTVKSPLPGIIYLHGGGWIIGSTDMYDELTRNLATSLSAVVASVDYRLAPEYPFPVPFEDCLKATKYFMVNAEKFGVDASRIAVSGDSAGGNLAMAVGTKLT------KEGQPPRLLGLIYPALQMLDFNTPSYVTYQSIPFVLQKKRMVSFYITYAFGNE-------NGIEKYLENRHVSETLRRAMETKVSID--LLPEKYQKLHVETNTAVDTNLALKVEKTMNNIYLCPL-LLDDDELYALPKTYLLTCEYDPLRDDGLMLARRWKDM 360
[Close]
BLAST of Neutral cholesterol ester hydrolase 1 vs. TrEMBL
Match: A0A210R707 (Arylacetamide deacetylase OS=Mizuhopecten yessoensis OX=6573 GN=KP79_PYT20177 PE=4 SV=1)

HSP 1 Score: 166.777 bits (421), Expect = 3.418e-43
Identity = 112/337 (33.23%), Postives = 176/337 (52.23%), Query Frame = 1 
Query:  286 MSDKTNLTIKRKLFDGVNVLVFSPIKRDRKGPAIVYYHGGGWAVMNPEIYSPFLANLARRLNTMIVAVDYRKAPEYPYPAPFNDALVATKYFLINCKEFDVDPNRIALMGDSAGGSLVVSVGYHLTAMKRASKIVHSPKVLISL-NPVLQVVDFSTPSYRDNLHDPILV-KARMARYYCIYAFGEQLSWTELRNCIEALISHRHLTVEAIQKVRGHVDWNNLLSGRGYDNRPR--SSFTQSVNQFSEKLSELVESVGFSPLSALNDSQLQILPPVYVYGSSKDPLRDDAKMLVARLKRLRSFGDYWEFKCFHVCFLLGRIGVKDEETSLKELISFFE 1284
            +SD+ +L +   LF GV V ++ P + + +   +VY HGGGW + N  IY     + AR L  ++V++DYR APE+P+P P  D L ATK+FL N K++ V+P RI + GDSAGG+L ++V   L       +    P   +SL  P LQ+VDF+ PSY D    P L+ K  M   +  YAFG +   T+  N       +RH++ E+   +R  V+ ++LL G   D + +  SSF +     +E++ + + +   SPL + +D  L+ LP + ++    DPL  D  +LV RL+ L +   Y  F      F   R  +   + +L     F +
Sbjct:   77 LSDE-DLEVTDTLFGGVKVRLYIPKESNPEHTGLVYIHGGGWYLGNVNIYDKKTRDFARSLKAVVVSIDYRLAPEHPFPVPLEDCLAATKHFLGNAKKYGVNPRRIGIGGDSAGGNLAMAVALKLAKEGETGEPTLPPLRSLSLVYPALQIVDFNLPSYVDYTGGPFLLNKQLMVSAWLTYAFGNENHLTDFFN-------NRHMSPESRLNLRRFVN-SSLLPGEYIDRKVKDSSSFNK---HLAEEVGDTLSNQFLSPLLS-SDEDLRKLPKMLLFTCQYDPLLSDGIILVKRLQNLGNPVVYQHFTGVQHGFFSSRFVMTKGKQALTAYKEFLK 400
[Close]
BLAST of Neutral cholesterol ester hydrolase 1 vs. TrEMBL
Match: A0A091JM34 (Neutral cholesterol ester hydrolase 1 (Fragment) OS=Egretta garzetta OX=188379 GN=Z169_10419 PE=4 SV=1)

HSP 1 Score: 164.081 bits (414), Expect = 1.867e-42
Identity = 115/321 (35.83%), Postives = 167/321 (52.02%), Query Frame = 1 
Query:  301 NLTIKRKLFDGVNVLVFSP-IKRD-RKGPAIVYYHGGGWAVMNP--EIYSPFLANLARRLNTMIVAVDYRKAPEYPYPAPFNDALVATKYFLIN--CKEFDVDPNRIALMGDSAGGSLVVSVGYHLTAMKRASKIVHSPKVLISLNPVLQVVDFSTPSYRDNLHDPILVKARMARYYCIYAFGE-QLSWTELRNCIEALISHRHLTVEAIQKVRGHVDWNNLLSGRGYDNRPRSSFTQSVNQFSEKLSELVESVGFSPLSALNDSQLQILPPVYVYGSSKDPLRDDAKMLVARLKR------LRSFGDYWEFKCFHVCFLL 1224
            ++TI   +FDGV V VF P +KRD R    IVY HGGGWA+ +    +Y+     +A  LN ++V+V+YR  PE  +P  F+DAL ATK+FL      E+ +DP+RIA+ GDSAGG+L  +V   L+   +   +   PK+   + PVLQ  DF+TPSY+ N++ P+L +  M  Y+  Y  G   L+ + L N      +H  L V      RG ++W +LL      N      T    +  +++  L++ V   PL A N++ LQ+ P  Y+     D LRDD  M   RL+       L  F D     CFH C + 
Sbjct:   33 DITITDAVFDGVEVRVFEPPVKRDERLKRGIVYIHGGGWALASARTSLYNNLCRIMAESLNAVVVSVEYRLVPEVCFPEQFHDALRATKHFLQPDVLAEYSIDPSRIAISGDSAGGNLAAAVCQQLS---KDEHLTIKPKLQALIYPVLQAFDFNTPSYQQNMNMPVLPRYVMINYWIDYFNGNYDLAHSLLIN------NHTALDVSQALSFRGRLNWTSLLPSSFKKNYKPVIQTTGKAEIIQEIPALLD-VRAVPLLAENET-LQLQPKTYILTCENDVLRDDGVMYAKRLENAGVEVTLDHFDD-----CFHGCMIF 337
[Close]
BLAST of Neutral cholesterol ester hydrolase 1 vs. TrEMBL
Match: A0A093EMQ6 (Neutral cholesterol ester hydrolase 1 (Fragment) OS=Tauraco erythrolophus OX=121530 GN=N340_03241 PE=4 SV=1)

HSP 1 Score: 161.77 bits (408), Expect = 1.219e-41
Identity = 118/330 (35.76%), Postives = 174/330 (52.73%), Query Frame = 1 
Query:  271 KLNYYMSDKTNLTIKRKLFDGVNVLVFSPIKR--DRKGPAIVYYHGGGWAVMNP--EIYSPFLANLARRLNTMIVAVDYRKAPEYPYPAPFNDALVATKYFLIN--CKEFDVDPNRIALMGDSAGGSLVVSVGYHLTAMKRASKIVHSPKVLISLNPVLQVVDFSTPSYRDNLHDPILVKARMARYYCIYAFGE-QLSWTELRNCIEALISHRHLTVEAIQKVRGHVDWNNLLSGRGYDNRPRSSFTQSVNQFSEKLSELVESVGFSPLSALNDSQLQILPPVYVYGSSKDPLRDDAKMLVARLKRLRSFG-----DYWEFKCFHVCFLL 1224
            KL    S+  N+T    +FDGV V VF P  +  +R   ++VY HGGGWA+ +    +Y+     +A  LN ++V+V+YR+ PE  +P  F+DAL ATK+FL      E+ VDP+RIA+ GDSAGG+L  +V   L+  +R   +   PK+   + PVLQ  DF+TPSY+ N++ PIL +  M  Y+  Y  G   L+ + L N      +H  L V      RG ++W +LL      +      T    +  E++  L++ V   PL A N++ LQ+ P  Y+     D LRDD  M     KRL + G     D++E  CFH C + 
Sbjct:   25 KLKSVSSEDINIT--DAVFDGVEVRVFEPPAKGDERLKRSVVYIHGGGWALASARTSLYNNLCRIMAESLNAVVVSVEYRRVPEVCFPEQFHDALRATKHFLQPDVLAEYSVDPSRIAISGDSAGGNLAAAVCQQLSKDER---LTIRPKLQALIYPVLQAFDFNTPSYQQNMNMPILPRFVMINYWIDYFNGNYDLAHSLLIN------NHTALDVGQALSFRGRLNWTSLLPSSFKKSYKPVIQTTGKAEIIEEIPALLD-VRAVPLLAENET-LQLQPKTYILTCENDVLRDDGVMYA---KRLENAGVDVTLDHFE-DCFHGCMIF 337
[Close]
BLAST of Neutral cholesterol ester hydrolase 1 vs. Ensembl Cavefish
Match: aadacl4 (chromosome 22 C1orf158 homolog [Source:NCBI gene;Acc:103033413])

HSP 1 Score: 139.043 bits (349), Expect = 3.071e-36
Identity = 102/312 (32.69%), Postives = 153/312 (49.04%), Query Frame = 1 
Query:  250 CFESGLGKLNYYMSDKTNLTIKRKLFDGVNVLVFSPIK-RDRKGPAIVYYHGGGWAVMNPEIYSPFLANLARRLNTMIVAVDYRKAPEYPYPAPFNDALVAT-KYFLINCKEFDVDPNRIALMGDSAGGSLVVSVGYHLTAMKRASKIVHSPKVLISLNPVLQVVDFSTPSYRDNLHDPILVKARMARYYCIYAFGEQLSWTELRNCIEALISHRHLTVEAIQKVRGHVDWNNL---LSGRGYDNRPRSSFTQSVNQFSEKLSELVESVGFSPLSALNDSQLQILPPVYVYGSSKDPLRDDAKMLVARLKRL 1170
            C E  +GK          L IK  +F GV V V+ P    D+K   ++Y+HGGGW + +  +Y     ++A   N  +V+V YR APE+ +PA  +D   AT  +F +   EF VDP+R+ L GDSAGG+L  ++   L   K+ +  V SP  L+ + P LQ+ DF+ PSY  N   P+L + + A Y+  Y  G      ++  C E L + RH+  E        +D  NL      R Y  +P    T    +  + + + ++   FSPL A  D  L++ P  ++     D LRDD  +   RLK L
Sbjct:   76 CRERAVGKPQ---PISPGLRIKDMMFGGVPVRVYEPTAPSDQKRRGMMYFHGGGWMMGSINMYDDVCQHIANESNITVVSVGYRLAPEHRFPAHLDDCEAATLHFFSVAEAEFGVDPHRVVLGGDSAGGNLSAALSQRLA--KKRTGDVPSPLALVLIYPALQMADFTLPSYLQNQSVPLLYRDKAAYYFLQYLNG------DVSVCQEVL-AGRHVPAELKAHYSKWLDPANLPPEFRERSY-QKPEQVVTTPDTEVYQIIKDGLQPE-FSPLLA-EDEDLRLTPSTFILTCEYDVLRDDGILFQKRLKDL 372
[Close]
BLAST of Neutral cholesterol ester hydrolase 1 vs. Ensembl Cavefish
Match: aadacl4 (chromosome 22 C1orf158 homolog [Source:NCBI gene;Acc:103033413])

HSP 1 Score: 138.272 bits (347), Expect = 6.100e-36
Identity = 97/295 (32.88%), Postives = 147/295 (49.83%), Query Frame = 1 
Query:  301 NLTIKRKLFDGVNVLVFSPIK-RDRKGPAIVYYHGGGWAVMNPEIYSPFLANLARRLNTMIVAVDYRKAPEYPYPAPFNDALVAT-KYFLINCKEFDVDPNRIALMGDSAGGSLVVSVGYHLTAMKRASKIVHSPKVLISLNPVLQVVDFSTPSYRDNLHDPILVKARMARYYCIYAFGEQLSWTELRNCIEALISHRHLTVEAIQKVRGHVDWNNL---LSGRGYDNRPRSSFTQSVNQFSEKLSELVESVGFSPLSALNDSQLQILPPVYVYGSSKDPLRDDAKMLVARLKRL 1170
             L IK   F GV V V+ P    D+K   ++Y+HGGGW + +  ++      +A+  NT + +V YR APE+ +PA  +D   AT  +F +   EF VDP+R+ L GDSAGG+L  ++   L   K+ +  V SP  L+ + P LQ+ DF+ PSY  N   P+L +ARM  YY  Y  G+        +  + +++ RH+  E        +D  NL      R Y    +   T    +    + + ++S  FSPL A  D  L++ P  ++     D LRDD  +   RLK L
Sbjct:   92 GLRIKDMTFGGVPVRVYEPTAPSDQKRRGMMYFHGGGWILGSINMHDNICRQIAKESNTTVASVGYRLAPEHRFPAHLDDCEAATLHFFSVAEAEFGVDPHRVVLGGDSAGGNLSAALSQRLA--KKRTGDVPSPLALVLIYPALQMADFTLPSYLQNQSVPLLYRARMVFYYLHYLNGDV-------SVCQDVLAGRHIPAELKAHYSKWLDPANLPPEFRERSYQKHEQED-TAHDGEVYHVIKDGLQSE-FSPLLA-EDDVLRLTPSTFILTCEYDVLRDDGILFHKRLKDL 374
[Close]
BLAST of Neutral cholesterol ester hydrolase 1 vs. Ensembl Cavefish
Match: aadacl4 (chromosome 22 C1orf158 homolog [Source:NCBI gene;Acc:103033413])

HSP 1 Score: 136.732 bits (343), Expect = 2.086e-35
Identity = 97/295 (32.88%), Postives = 147/295 (49.83%), Query Frame = 1 
Query:  301 NLTIKRKLFDGVNVLVFSPIK-RDRKGPAIVYYHGGGWAVMNPEIYSPFLANLARRLNTMIVAVDYRKAPEYPYPAPFNDALVAT-KYFLINCKEFDVDPNRIALMGDSAGGSLVVSVGYHLTAMKRASKIVHSPKVLISLNPVLQVVDFSTPSYRDNLHDPILVKARMARYYCIYAFGEQLSWTELRNCIEALISHRHLTVEAIQKVRGHVDWNNL---LSGRGYDNRPRSSFTQSVNQFSEKLSELVESVGFSPLSALNDSQLQILPPVYVYGSSKDPLRDDAKMLVARLKRL 1170
             L IK   F GV V V+ P    D+K   ++Y+HGGGW + +  ++      +A+  NT + +V YR APE+ +PA  +D   AT  +F +   EF VDP+R+ L GDSAGG+L  ++   L   K+ +  V SP  L+ + P LQ+ DF+ PSY  N   P+L + + A Y+  Y  G      ++  C E L + RH+  E        +D  NL      R Y  +P    T    +  + + + ++   FSPL A  D  L++ P  ++     D LRDD  +   RLK L
Sbjct:   90 GLRIKDMTFGGVPVRVYEPTAPSDQKRRGMMYFHGGGWILGSINMHDNICRQIAKESNTTVASVGYRLAPEHRFPAHLDDCEAATLHFFSVAEAEFGVDPHRVVLGGDSAGGNLSAALSQRLA--KKRTGDVPSPLALVLIYPALQMADFTLPSYLQNQSVPLLYRDKAAYYFLQYLNG------DVSVCQEVL-AGRHVPAELKAHYSKWLDPANLPPEFRERSY-QKPEQVVTTPDTEVYQIIKDGLQPE-FSPLLA-EDEDLRLTPSTFILTCEYDVLRDDGILFQKRLKDL 372
[Close]
BLAST of Neutral cholesterol ester hydrolase 1 vs. Ensembl Cavefish
Match: nceh1b.1 (neutral cholesterol ester hydrolase 1 [Source:NCBI gene;Acc:103023841])

HSP 1 Score: 136.346 bits (342), Expect = 2.625e-35
Identity = 108/340 (31.76%), Postives = 168/340 (49.41%), Query Frame = 1 
Query:  325 FDGVNVLVFSPI----KRDRKGPAIVYYHGGGWAVMNPEI--YSPFLANLARRLNTMIVAVDYRKAPEYPYPAPFNDALVATKYFLIN--CKEFDVDPNRIALMGDSAGGSLVVSVGYHLTAMKRASKIVHSPKVLISLNPVLQVVDFSTPSYRDNLHDPILVKARMARYYCIYAFGEQLSWTELRNCIEALISHRHLTV----EAIQKVRGHVDWNNLLSGRGYDNRPRSSFTQSVNQFSEKLSELVESVGFSPLSALNDSQLQILPPVYVYGSSKDPLRDDAKMLVARLKR--LRSFGDYWEFKCFHVCFLLG----RIGVKDEETSLKELISFFENN 1290
            FDGV   VF  +    +R ++G  ++Y+HGGGWA+    +  Y      +A  L+ +I++VDYR APE  +P P+NDAL A ++ L       + +DP R+A+ GDSAGG+L  +V   L   K  S      KV   + PVLQ +DF+TPSY+ N + PIL +  MAR++  Y  G+        + +  L+++ H  V    EA+   +   +W  LL+     +              E+L  L++ V  +PL A  +  L+++PP Y+     D LRDD  M   RL+   +    D++  + FH C + G    R  V     S+   I + E N
Sbjct:   87 FDGVQARVFESVTPGSRRLKRG--VIYFHGGGWALGTGRMRSYDLLCRTMAEELDAVIISVDYRLAPEVHFPEPYNDALRACRHILRAEVLALYSMDPERVAVSGDSAGGNLAAAVAQQLALDKSVSVGF---KVQALVYPVLQALDFNTPSYQQNGNVPILYRTNMARFWLEYLSGDM-------DLVPLLLANNHTAVDQSQEAMSAAKAKTNWTALLAPAFQKHYKPVVPGLGSPGLLEQLPALLD-VRAAPLLAEKEV-LKLVPPAYIMTCEHDVLRDDGLMYAQRLEEAGVTVTSDHYA-EGFHGCMVFGFWPARFSVGTR--SMTNYIRWLEQN 409
[Close]
BLAST of Neutral cholesterol ester hydrolase 1 vs. Ensembl Cavefish
Match: aadac (arylacetamide deacetylase [Source:ZFIN;Acc:ZDB-GENE-130530-713])

HSP 1 Score: 134.035 bits (336), Expect = 4.258e-34
Identity = 102/303 (33.66%), Postives = 152/303 (50.17%), Query Frame = 1 
Query:  304 LTIKRKLFDGVNVLVFSPIKRDRKGP-----AIVYYHGGGWAV----MNPEIYSPFLANLARRLNTMIVAVDYRKAPEYPYPAPFNDALVATKYFLIN--CKEFDVDPNRIALMGDSAGGSLVVSVGYHLTAMKRASKIVHSPKVLISLNPVLQVVDFSTPSYRDNLHDPILVKARMARYYCIYAFGEQLSWTELRNCIEALISHRHLTVEAIQKVRGHVDWNNLLSG---RGYD-NRPRSSFTQSVNQFSEKLSELVESVGFSPLSALNDSQLQILPPVYVYGSSKDPLRDDAKMLVARLKR 1167
            + +  +LFDGV V+V+ P  R  KG      AI+Y HGGGW +    M P  Y      +   LN ++V+V+YR AP + +PAPF D     KY       + + VD  R+A+ GDSAGG+L  +V   L      S  +   KV   L PVLQ VD  TPSY+ N + PIL +  M R++  Y       ++  ++   A++++ H   E+   ++  V+W+  L     R Y+ + P  + T++    +E    LV+    SPL  + D  L+ LP  YV     D LRDD  M V RL++
Sbjct:  147 VQVSEELFDGVEVVVYQP--RQEKGAGEARRAIIYLHGGGWCLGSSRMGP--YDLMARQMVTELNAVVVSVEYRLAPAHRFPAPFEDVYRVVKYLFQPDVLERYKVDRERVAVSGDSAGGNLAAAVTQQLQLEPENSIKL---KVQALLYPVLQAVDLYTPSYQQNQNMPILPRTLMVRFWSEY-------FSSDKSLFRAMMANDHNGPESAAMLK-FVNWSAFLPESYRRAYNYSAPPVAQTETDQHSNEPARSLVDPRA-SPL-LVPDEVLRPLPKAYVLTCEYDVLRDDGVMYVTRLRQ 432
[Close]
BLAST of Neutral cholesterol ester hydrolase 1 vs. Ensembl Yeast
Match: SAY1 (Sterol deacetylase; component of the sterol acetylation/deacetylation cycle along with Atf2p; active both in the endoplasmic reticulum (ER) and in lipid droplets; integral membrane protein with active site in the ER lumen; green fluorescent protein (GFP)-fusion protein localizes to the ER [Source:SGD;Acc:S000003495])

HSP 1 Score: 45.8246 bits (107), Expect = 8.252e-6
Identity = 37/123 (30.08%), Postives = 61/123 (49.59%), Query Frame = 1 
Query:  379 PAIVYYHGGGWAV-MNPEIYSPFLANLARRLNTMIVAV-DYR------KAPEYPYPAPFNDALVATKYFLINCKEFDVDPNRIALMGDSAGGSLVVSVGYHLTAMKRASKIVHSPKVLISLNP 723
            P +V+YHGGG+A+ + P  +S FL N+      M + V DY       ++ +YP     N A+       + CK        + +MGDSAGG+ V+++  +L    R       PK +I+++P
Sbjct:  170 PVLVFYHGGGYALKLTPTSFS-FLNNMRNAFPKMAILVPDYTVTATDDQSKKYPLQILQNVAIFDYVVKTMGCK-------NVVIMGDSAGGNAVLNIVLYLRKCHREI----YPKKVIAISP 280
[Close]
BLAST of Neutral cholesterol ester hydrolase 1 vs. Ensembl Nematostella
Match: EDO29815 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7T2K0])

HSP 1 Score: 63.1586 bits (152), Expect = 1.951e-11
Identity = 61/227 (26.87%), Postives = 99/227 (43.61%), Query Frame = 1 
Query:  493 YRKAPEYPYPAPFNDALVATKYFLINCKEFDVDPNRIALMGDSAGGSLVVSVGYHLT--AMKRASKIVHSPKVLISLNPVLQVVDFSTPSYRDNLHDPILVKARMARYYCIYAFGEQLSWTELRNCIEALISHRHLTVEAIQKVRGHVDWNNLLSGRGYDNRPRSSFTQSVNQFSEKLSELVESVGFSPL-SALNDSQLQILPPVYVYGSSKDPLRDDAKMLVARLK 1164
            YR+APEY YP    D        L N  ++ ++  R+ + GDSAGG++  +V + L   A +  SK   + ++LI   P LQ++D + PSY  + +D I  +  +A Y  +Y  G     T L   I A    RHL      +   +V    +      D+    +  + +      LSE   +    P+ S L     +  P   +  +  DPLRD+  +   R+K
Sbjct:    5 YRQAPEYIYPTSMMDCYNVAIELLNNGSQYGINVKRVMVGGDSAGGNIAAAVTHTLAGVAERHCSKQYLAGQILIY--PALQMLDLNLPSYVKSKNDLIASQRDIADYVSLYLNGS----TALAAAILAGNHSRHLEN---TRYMAYVRPKGIPDADDNDDDDDDNKNEVIKNPEMDLSEAAAAAIIDPVASPLLAKTFRGTPQTLLITAEFDPLRDEGFLYAERIK 222
[Close]
BLAST of Neutral cholesterol ester hydrolase 1 vs. Ensembl Nematostella
Match: EDO37936 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SEE6])

HSP 1 Score: 62.7734 bits (151), Expect = 3.313e-11
Identity = 45/136 (33.09%), Postives = 68/136 (50.00%), Query Frame = 1 
Query:  493 YRKAPEYPYPAPFNDALVATKYFLINCKEFDVDPNRIALMGDSAGGSLVVSVGYHLT--AMKRASKIVHSPKVLISLNPVLQVVDFSTPSYRDNLHDPILVKARMARYYCIYAFGEQLSWTELRNCIEALISHRHL 894
            YR+APEY YP    D        L N  ++ ++  R+ + GDSAGG++  +V + L   A +  SK   + ++LI   P LQ++D + PSY  + +D I  +  +A Y  +Y  G     T L   I A    RHL
Sbjct:    1 YRQAPEYIYPTSMMDCYNVAIELLNNGSQYGINVKRVMVGGDSAGGNIAAAVTHTLAGVAERHCSKQYLAGQILIY--PALQMLDLNLPSYVKSKNDLIASQRDIADYVSLYLNGS----TALAAAILAGNHSRHL 130
[Close]
BLAST of Neutral cholesterol ester hydrolase 1 vs. Ensembl Nematostella
Match: EDO39376 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SAD0])

HSP 1 Score: 64.3142 bits (155), Expect = 4.989e-11
Identity = 48/174 (27.59%), Postives = 81/174 (46.55%), Query Frame = 1 
Query:  352 SPIKRDRKGPAIVYYHGGGWAVMNPEIYSPFLANLARRLNTMIVAVDYRKAPEYPYPAPFNDALVATKYFLINCKEFDVDPNRIALMGDSAGGSLVVSVGYHLTAMKRASKIVHSPKVLISLNPVLQVVDFSTPSYRDNLHDPILVKARMARYYCIYAFGEQLSWTELRNCIEA 873
            S +K   KG  I++ HGGG+   + + +  +L   AR LN  I++VDY  AP+ P+P    +   A  + L N  +       + + GDSAGG+L V++      M+ A   +  P  +++      V    +PS   +L DP+L    +    C+ A+   L  +    CI+ 
Sbjct:  314 SKLKPRAKG-LILHIHGGGFVAQSSKSHEVYLRMWARDLNVPILSVDYSLAPDNPFPRALEECFFAYAWALKNPDKLGTTLEYVCVAGDSAGGNLSVAL-----CMRAAEYGIRRPDSVLAAYAPFNVQYIPSPSRLLSLMDPLLPTGILEA--CLKAYA-GLGKSPFEECIKT 478
[Close]
BLAST of Neutral cholesterol ester hydrolase 1 vs. Ensembl Medaka
Match: aadac (arylacetamide deacetylase [Source:NCBI gene;Acc:101172918])

HSP 1 Score: 124.405 bits (311), Expect = 5.807e-31
Identity = 89/305 (29.18%), Postives = 153/305 (50.16%), Query Frame = 1 
Query:  286 MSDKTNLTIKRKLFDGVNVLVFSPIKRDRKGP---AIVYYHGGGWAVMNPEI--YSPFLANLARRLNTMIVAVDYRKAPEYPYPAPFNDALVATKYFLIN--CKEFDVDPNRIALMGDSAGGSLVVSVGYHLTAMKRASKIVHSPKVLISLNPVLQVVDFSTPSYRDNLHDPILVKARMARYYCIYAFGEQLSWTELRNCIEALISHRHLTVEAIQKVRGHVDWNNLLSGRGYD--NRPRSSFTQSVNQFSEKLSELVESVG---FSPLSALNDSQLQILPPVYVYGSSKDPLRDDAKMLVARLK 1164
            +SD+ ++ +    FDGV+V+++ P  ++       A++Y HGGGW + +P +  Y      +   L+ ++++VDYR AP + +P P+ D     K+F       ++ VDP R+A+ GDSAGG+L  +V   L   +    I    + LI   PVLQ +D +TPSY+ N + PIL +  M R++  Y       +T  +    A++++ H + E+   ++  V+W+  L    +   N    + +Q   + +  + E   S      SPL  + D+ L+ LP  Y+     D LRDD  M   RL+
Sbjct:   75 VSDE-HVKVTEDTFDGVDVVLYQPNVQEAGTNLRRAVIYLHGGGWCLGSPRMSPYDLLARKIVTELDAVVLSVDYRLAPPHHFPIPYEDVYRVVKHFFRKEVLAQYSVDPERVAVSGDSAGGNLAAAVSQQLRK-EPGQPIKLKAQALIY--PVLQALDLNTPSYQQNQNMPILPRTLMVRFWSEY-------FTTDKALFRAMMANTHNSPESSILLK-FVNWSTFLPETYHKKYNYSAPAISQGAEREAASMEEPSRSFADPRASPL-LVPDADLRFLPKAYILTCEYDVLRDDGIMYATRLR 366
[Close]
BLAST of Neutral cholesterol ester hydrolase 1 vs. Ensembl Medaka
Match: ENSORLT00000016643.2 (neutral cholesterol ester hydrolase 1 [Source:NCBI gene;Acc:101172853])

HSP 1 Score: 122.865 bits (307), Expect = 1.540e-30
Identity = 106/339 (31.27%), Postives = 159/339 (46.90%), Query Frame = 1 
Query:  331 GVNVLVFSPIKRDRKGPAIVYYHGGGWAVMNPEI--YSPFLANLARRLNTMIVAVDYRKAPEYPYPAPFNDALVATKYFLIN--CKEFDVDPNRIALMGDSAGGSLVVSVGYHLTAMKRASKIVHSPKVLISLNPVLQVVDFSTPSYRDNLHDPILVKARMARYYCIYAFGEQLSWTELRNCIEALISHRHLTVEA---IQKVRGHVDWNNLLSGRGYDNRPRSSFTQSVNQFSE-----KLSELVESVGFSPLSALNDSQLQILPPVYVYGSSKDPLRDDAKMLVARLKRLRSFG-----DYWEFKCFHVCFLLGRIGVKDE--ETSLKELISFFENN 1290
             V   VF PI        ++Y+HGGGWA+ +  +  Y      +A  L+ +I++VDYR APE  +P  ++DA+ A++ FL +   + + +DP R+   GDSAGG+L  +V   L +      +  + KV   + PVLQ +DF TPSY+ N   PIL +  M +++  Y  G   S   L      L+++ H +++        R  ++W  LL         R SF Q V +        KL  L + V  +PL A  D  L+  P  YV     D LRDD  M V   +RLR  G     D++E   FH C     + V     + SL   I + + N
Sbjct:   88 AVPTRVFQPIGGAGLKRGVIYFHGGGWALCSGRMRSYDLLCRKMAEDLDAVIMSVDYRLAPEAVFPDQYHDAVAASRAFLSSEVLQRYGIDPERVCASGDSAGGNLAAAVVQELIS---DPTLTVNFKVQALIYPVLQALDFLTPSYQQNQDVPILYRPLMVQFWLEY-LGADASLEPL------LLANNHSSLDQPGISAATRSKLNWTALLPAER-----RKSFQQVVKETGSGGLVGKLPGLTD-VRAAPLLAEQDV-LRRTPKAYVMTCEFDVLRDDGLMYV---RRLRDAGVSVTSDHYE-DGFHGCMAFAFLPVMSSVGQRSLNNYIRWLDQN 405
[Close]
BLAST of Neutral cholesterol ester hydrolase 1 vs. Ensembl Medaka
Match: ENSORLT00000027750.1 (neutral cholesterol ester hydrolase 1 [Source:NCBI gene;Acc:101172853])

HSP 1 Score: 122.865 bits (307), Expect = 1.540e-30
Identity = 106/339 (31.27%), Postives = 159/339 (46.90%), Query Frame = 1 
Query:  331 GVNVLVFSPIKRDRKGPAIVYYHGGGWAVMNPEI--YSPFLANLARRLNTMIVAVDYRKAPEYPYPAPFNDALVATKYFLIN--CKEFDVDPNRIALMGDSAGGSLVVSVGYHLTAMKRASKIVHSPKVLISLNPVLQVVDFSTPSYRDNLHDPILVKARMARYYCIYAFGEQLSWTELRNCIEALISHRHLTVEA---IQKVRGHVDWNNLLSGRGYDNRPRSSFTQSVNQFSE-----KLSELVESVGFSPLSALNDSQLQILPPVYVYGSSKDPLRDDAKMLVARLKRLRSFG-----DYWEFKCFHVCFLLGRIGVKDE--ETSLKELISFFENN 1290
             V   VF PI        ++Y+HGGGWA+ +  +  Y      +A  L+ +I++VDYR APE  +P  ++DA+ A++ FL +   + + +DP R+   GDSAGG+L  +V   L +      +  + KV   + PVLQ +DF TPSY+ N   PIL +  M +++  Y  G   S   L      L+++ H +++        R  ++W  LL         R SF Q V +        KL  L + V  +PL A  D  L+  P  YV     D LRDD  M V   +RLR  G     D++E   FH C     + V     + SL   I + + N
Sbjct:   88 AVPTRVFQPIGGAGLKRGVIYFHGGGWALCSGRMRSYDLLCRKMAEDLDAVIMSVDYRLAPEAVFPDQYHDAVAASRAFLSSEVLQRYGIDPERVCASGDSAGGNLAAAVVQELIS---DPTLTVNFKVQALIYPVLQALDFLTPSYQQNQDVPILYRPLMVQFWLEY-LGADASLEPL------LLANNHSSLDQPGISAATRSKLNWTALLPAER-----RKSFQQVVKETGSGGLVGKLPGLTD-VRAAPLLAEQDV-LRRTPKAYVMTCEFDVLRDDGLMYV---RRLRDAGVSVTSDHYE-DGFHGCMAFAFLPVMSSVGQRSLNNYIRWLDQN 405
[Close]
BLAST of Neutral cholesterol ester hydrolase 1 vs. Ensembl Medaka
Match: nceh1a (neutral cholesterol ester hydrolase 1 [Source:NCBI gene;Acc:101167661])

HSP 1 Score: 102.449 bits (254), Expect = 2.690e-23
Identity = 85/292 (29.11%), Postives = 136/292 (46.58%), Query Frame = 1 
Query:  325 FDGVNVLVFSPIKRD----RKGPAIVYYHGGGWAVMNPEI--YSPFLANLARRLNTMIVAVDYRKAPEYPYPAPFNDALVATKYFLIN--CKEFDVDPNRIALMGDSAGGSLVVSVGYHLTAMKRASKIVHSPKVLISLNPVLQVVDFSTPSYRDNLHDPILVKARMARYYCIYAFGEQLSWTELRNCIEALISHRH---LTVEAIQKVRGHVDWNNLLSGRGYDNR-PRSSFTQSVNQFSEKLSELVESVGFSPLSALNDSQLQILPPVYVYGSSKDPLRDDAKMLVARLK 1164
            F GV V V+ P        R+G  ++Y HGGGWA  + +   Y    + ++  LN ++V+VDYR  PE  +P PF D L A K+FL       + +DP R+A+ GDSAGG+L  +V   ++       +  S + LI   PVLQ +DF+TPSY  N +  +L +  M R++  Y   +        + +   I++ H   L      ++R  +DW  LL  +   N  P     +   +  +K+  L++            + +   P  ++     D LRDD  M   RL+
Sbjct:   93 FAGVPVRVYEPPAGGEGHLRRG--LMYLHGGGWAFGSGKFGTYDSISSMVSDELNCVVVSVDYRLYPEVHFPEPFLDCLAAAKHFLSPEVLARYAIDPERVAVSGDSAGGNLAAAVAQEIST-DDGVPVKFSVQALI--YPVLQALDFNTPSYVQNQNMAVLPRHTMVRFWLQYLNAD-------LSLLPQFIANNHSSSLHSAFTTELRSRLDWTVLLPPKFKKNHTPLVVEKKGSPEILKKVPGLLDRRAAP--LLAEAAAIAKCPRAFIMTCEYDVLRDDGLMYAQRLR 370
[Close]
BLAST of Neutral cholesterol ester hydrolase 1 vs. Ensembl Medaka
Match: lipeb (lipase E, hormone sensitive type [Source:NCBI gene;Acc:101157970])

HSP 1 Score: 97.4413 bits (241), Expect = 3.090e-21
Identity = 79/301 (26.25%), Postives = 141/301 (46.84%), Query Frame = 1 
Query:  295 KTNLTIKRKLFDGVNVLVFSPIKRDRKGP-AIVYYHGGGWAVMNPEIYSPFLANLARRLNTMIVAVDYRKAPEYPYPAPFNDALVATKYFLINCKEFDVDPNRIALMGDSAGGSLVVSVGYHLTAMKRASKIVHSPKVLISLNPVLQVVDFSTPSYRDNLHDPILVKARMARYYCIYAFGEQLSWTELRNCIEALISHRHLTVEAIQKVRGHVDWNNLL--SGRGYDNRPRSSFTQSV-----NQFSE---KLSELVESVGFSPLSALNDSQLQILPPVYVYGSSKDPLRDDAKMLVARLK 1164
            +T L++ R     +++ +    KR    P  ++++HGGG+     + + P+L + ++ L   I++VDY  APE P+P    +   A  + L N         ++ L GDSAGG+L V+     T M+ A+  V  P  +++  P   +  +++PS    L DP+L  + ++R    YA  E  +  ++       +  R   +      +G  +W + L  S RG   +    F         +QF+E   + S + +    SPL A  DS L+ LPP+++   + DP+ DD+ M   RL+
Sbjct:  286 ETLLSMSRSEGGAISLSLGLKTKRLPSSPFLLIHFHGGGFVAQTSKSHEPYLKSWSQDLGVPILSVDYSLAPEAPFPRALEECFYAYCWALRNHHLLGWTGEKVCLAGDSAGGNLCVT-----TCMRAAAFGVRMPDGVVAAYPATLLTAYASPSRLLTLMDPLLPLSVLSRCLSAYAGSEPQTEKQVERVSTLSLVKRDTALFLRDFRQGASNWIHSLLDSNRGSALQHPREFPLGFEPLRSDQFAEMKLQSSPVFKDPFCSPLLA-PDSMLKGLPPIHIVACALDPMLDDSVMFAKRLR 580
[Close]
BLAST of Neutral cholesterol ester hydrolase 1 vs. Planmine SMEST
Match: SMESG000076502.1 (SMESG000076502.1)

HSP 1 Score: 434.491 bits (1116), Expect = 1.914e-153
Identity = 208/211 (98.58%), Postives = 211/211 (100.00%), Query Frame = 1 
Query:  667 MKRASKIVHSPKVLISLNPVLQVVDFSTPSYRDNLHDPILVKARMARYYCIYAFGEQLSWTELRNCIEALISHRHLTVEAIQKVRGHVDWNNLLSGRGYDNRPRSSFTQSVNQFSEKLSELVESVGFSPLSALNDSQLQILPPVYVYGSSKDPLRDDAKMLVARLKRLRSFGDYWEFKCFHVCFLLGRIGVKDEETSLKELISFFENNAIL 1299
            MKRASKIVHSPKVLISLNPVLQVVDFSTPSYRDNLHDPILVKARMARYYCIYAFGEQLSWTELRNCIEALI+HRHLTVEAIQKVRGHVDWNNLLSGRGYDNRPRSSFTQSVNQFSEKLSELVESVGFSPLSALNDSQLQILPPVY+YGSSKDPLRDDAKML+ARLKRLRSFGDYWEFKCFHVCFLLGRIGVKDEETSLKELISFFENNAIL
Sbjct:    1 MKRASKIVHSPKVLISLNPVLQVVDFSTPSYRDNLHDPILVKARMARYYCIYAFGEQLSWTELRNCIEALITHRHLTVEAIQKVRGHVDWNNLLSGRGYDNRPRSSFTQSVNQFSEKLSELVESVGFSPLSALNDSQLQILPPVYLYGSSKDPLRDDAKMLMARLKRLRSFGDYWEFKCFHVCFLLGRIGVKDEETSLKELISFFENNAIL 211
[Close]
BLAST of Neutral cholesterol ester hydrolase 1 vs. Planmine SMEST
Match: SMESG000076513.1 (SMESG000076513.1)

HSP 1 Score: 366.311 bits (939), Expect = 6.936e-127
Identity = 185/211 (87.68%), Postives = 187/211 (88.63%), Query Frame = 1 
Query:  667 MKRASKIVHSPKVLISLNPVLQVVDFSTPSYRDNLHDPILVKARMARYYCIYAFGEQLSWTELRNCIEALISHRHLTVEAIQKVRGHVDWNNLLSGRGYDNRPRSSFTQSVNQFSEKLSELVESVGFSPLSALNDSQLQILPPVYVYGSSKDPLRDDAKMLVARLKRLRSFGDYWEFKCFHVCFLLGRIGVKDEETSLKELISFFENNAIL 1299
            MKRASKIVHSPKVLISLNPVLQVVDFSTPSYRDNLHDPILVKARMARYYCIYAFG        R+C                KVRGHVDWNNLLSGRGYDNRPRSSFTQSVNQFSEKLSELVESVGFSPLSALNDSQLQILPPVYVYGSSKDPLRDDAKMLVARLKRLRSFGDYWEFKCFHVCFLLGRIGVKDEETSLKELI+FFENNAIL
Sbjct:    1 MKRASKIVHSPKVLISLNPVLQVVDFSTPSYRDNLHDPILVKARMARYYCIYAFGSSYPG---RSC----------------KVRGHVDWNNLLSGRGYDNRPRSSFTQSVNQFSEKLSELVESVGFSPLSALNDSQLQILPPVYVYGSSKDPLRDDAKMLVARLKRLRSFGDYWEFKCFHVCFLLGRIGVKDEETSLKELINFFENNAIL 192
[Close]
BLAST of Neutral cholesterol ester hydrolase 1 vs. Planmine SMEST
Match: SMESG000076519.1 (SMESG000076519.1)

HSP 1 Score: 241.506 bits (615), Expect = 6.832e-79
Identity = 117/118 (99.15%), Postives = 118/118 (100.00%), Query Frame = 1 
Query:   73 MKNLIKASLTVLIISVLIYKFVDFRRYDDFILRTAVNMHIFLMDADIILRSIHIKGVYRCFESGLGKLNYYMSDKTNLTIKRKLFDGVNVLVFSPIKRDRKGPAIVYYHGGGWAVMNP 426
            MKNLIKASLTVLIISVLIYKFVDFRRYDDFILRTAVNMHIFLMDADIILRSIHIKGVYRCFESGLGKLNYYMSDKTNLTIKRKLFDGVNVL+FSPIKRDRKGPAIVYYHGGGWAVMNP
Sbjct:    1 MKNLIKASLTVLIISVLIYKFVDFRRYDDFILRTAVNMHIFLMDADIILRSIHIKGVYRCFESGLGKLNYYMSDKTNLTIKRKLFDGVNVLIFSPIKRDRKGPAIVYYHGGGWAVMNP 118
[Close]
BLAST of Neutral cholesterol ester hydrolase 1 vs. Planmine SMEST
Match: SMESG000076505.1 (SMESG000076505.1)

HSP 1 Score: 240.736 bits (613), Expect = 1.456e-78
Identity = 116/118 (98.31%), Postives = 118/118 (100.00%), Query Frame = 1 
Query:   73 MKNLIKASLTVLIISVLIYKFVDFRRYDDFILRTAVNMHIFLMDADIILRSIHIKGVYRCFESGLGKLNYYMSDKTNLTIKRKLFDGVNVLVFSPIKRDRKGPAIVYYHGGGWAVMNP 426
            MKNLIKASLTVLIISVLIYKFVDFRRYDDFILRTAVNMHIFLMDADIILRSIHIKGVYRCFESGLGKLNYYM+DKTNLTIKRKLFDGVNVL+FSPIKRDRKGPAIVYYHGGGWAVMNP
Sbjct:    1 MKNLIKASLTVLIISVLIYKFVDFRRYDDFILRTAVNMHIFLMDADIILRSIHIKGVYRCFESGLGKLNYYMTDKTNLTIKRKLFDGVNVLIFSPIKRDRKGPAIVYYHGGGWAVMNP 118
[Close]
BLAST of Neutral cholesterol ester hydrolase 1 vs. Planmine SMEST
Match: SMESG000076519.1 (SMESG000076519.1)

HSP 1 Score: 160.229 bits (404), Expect = 4.117e-48
Identity = 75/76 (98.68%), Postives = 76/76 (100.00%), Query Frame = 1 
Query:  199 MDADIILRSIHIKGVYRCFESGLGKLNYYMSDKTNLTIKRKLFDGVNVLVFSPIKRDRKGPAIVYYHGGGWAVMNP 426
            MDADIILRSIHIKGVYRCFESGLGKLNYYMSDKTNLTIKRKLFDGVNVL+FSPIKRDRKGPAIVYYHGGGWAVMNP
Sbjct:    1 MDADIILRSIHIKGVYRCFESGLGKLNYYMSDKTNLTIKRKLFDGVNVLIFSPIKRDRKGPAIVYYHGGGWAVMNP 76
The following BLAST results are available for this feature:
BLAST of Neutral cholesterol ester hydrolase 1 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5
Match NameE-valueIdentityDescription
NCEH15.575e-4132.03neutral cholesterol ester hydrolase 1 [Source:HGNC... [more]
NCEH11.495e-4032.03neutral cholesterol ester hydrolase 1 [Source:HGNC... [more]
NCEH12.166e-3531.61neutral cholesterol ester hydrolase 1 [Source:HGNC... [more]
AADACL29.802e-3331.96arylacetamide deacetylase like 2 [Source:HGNC Symb... [more]
AADACL29.802e-3331.96arylacetamide deacetylase like 2 [Source:HGNC Symb... [more]
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BLAST of Neutral cholesterol ester hydrolase 1 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 5
Match NameE-valueIdentityDescription
nceh-17.234e-2528.82Neutral Cholesterol Ester Hydrolase homolog [Sour... [more]
T09B9.18.112e-2426.63pep chromosome:WBcel235:X:9757271:9759306:1 gene:W... [more]
nceh-13.410e-2128.47Neutral Cholesterol Ester Hydrolase homolog [Sour... [more]
trcs-12.964e-1926.42TRansport of membrane to Cell Surface [Source:Uni... [more]
trcs-12.964e-1926.42TRansport of membrane to Cell Surface [Source:Uni... [more]
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BLAST of Neutral cholesterol ester hydrolase 1 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 4
Match NameE-valueIdentityDescription
Hsl3.469e-927.78gene:FBgn0034491 transcript:FBtr0086270[more]
Hsl3.469e-927.78gene:FBgn0034491 transcript:FBtr0086271[more]
Hsl3.469e-927.78gene:FBgn0034491 transcript:FBtr0086272[more]
alpha-Est77.193e-833.33gene:FBgn0015575 transcript:FBtr0081550[more]
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BLAST of Neutral cholesterol ester hydrolase 1 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
nceh1b.11.011e-3630.05neutral cholesterol ester hydrolase 1b, tandem dup... [more]
aadac1.800e-3633.11arylacetamide deacetylase [Source:ZFIN;Acc:ZDB-GEN... [more]
nceh1a7.603e-3533.33neutral cholesterol ester hydrolase 1a [Source:ZFI... [more]
nceh1a7.603e-3533.33neutral cholesterol ester hydrolase 1a [Source:ZFI... [more]
aadacl48.488e-3130.82arylacetamide deacetylase-like 4 [Source:ZFIN;Acc:... [more]
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BLAST of Neutral cholesterol ester hydrolase 1 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5
Match NameE-valueIdentityDescription
nceh11.324e-4132.92neutral cholesterol ester hydrolase 1 [Source:NCBI... [more]
cog62.000e-3532.78component of oligomeric golgi complex 6 [Source:Xe... [more]
meiob2.700e-3533.01meiosis specific with OB domains [Source:Xenbase;A... [more]
ENSXETT00000037153.11.640e-2533.92pep primary_assembly:Xenopus_tropicalis_v9.1:KV464... [more]
ENSXETT00000037158.13.618e-2533.92pep primary_assembly:Xenopus_tropicalis_v9.1:KV464... [more]
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BLAST of Neutral cholesterol ester hydrolase 1 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Nceh15.146e-4131.74neutral cholesterol ester hydrolase 1 [Source:MGI ... [more]
Aadacl23.372e-3029.97arylacetamide deacetylase like 2 [Source:MGI Symbo... [more]
Aadac3.686e-2928.20arylacetamide deacetylase [Source:MGI Symbol;Acc:M... [more]
Aadacl2fm38.497e-2829.63AADACL2 family member 3 [Source:MGI Symbol;Acc:MGI... [more]
Aadacl2fm21.266e-2728.52AADACL2 family member 2 [Source:MGI Symbol;Acc:MGI... [more]
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BLAST of Neutral cholesterol ester hydrolase 1 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|Q6PIU2|NCEH1_HUMAN2.677e-4032.03Neutral cholesterol ester hydrolase 1 OS=Homo sapi... [more]
sp|Q8BLF1|NCEH1_MOUSE3.600e-4031.74Neutral cholesterol ester hydrolase 1 OS=Mus muscu... [more]
sp|Q5R8Y5|NCEH1_PONAB5.359e-4032.45Neutral cholesterol ester hydrolase 1 OS=Pongo abe... [more]
sp|B2GV54|NCEH1_RAT2.765e-3933.23Neutral cholesterol ester hydrolase 1 OS=Rattus no... [more]
sp|Q0P5B7|AAAD_BOVIN7.123e-3931.64Arylacetamide deacetylase OS=Bos taurus OX=9913 GN... [more]
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BLAST of Neutral cholesterol ester hydrolase 1 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
A0A210PFU61.871e-5038.51Arylacetamide deacetylase OS=Mizuhopecten yessoens... [more]
A0A210PF692.050e-5037.42Arylacetamide deacetylase OS=Mizuhopecten yessoens... [more]
A0A210R7073.418e-4333.23Arylacetamide deacetylase OS=Mizuhopecten yessoens... [more]
A0A091JM341.867e-4235.83Neutral cholesterol ester hydrolase 1 (Fragment) O... [more]
A0A093EMQ61.219e-4135.76Neutral cholesterol ester hydrolase 1 (Fragment) O... [more]
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BLAST of Neutral cholesterol ester hydrolase 1 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
aadacl43.071e-3632.69chromosome 22 C1orf158 homolog [Source:NCBI gene;A... [more]
aadacl46.100e-3632.88chromosome 22 C1orf158 homolog [Source:NCBI gene;A... [more]
aadacl42.086e-3532.88chromosome 22 C1orf158 homolog [Source:NCBI gene;A... [more]
nceh1b.12.625e-3531.76neutral cholesterol ester hydrolase 1 [Source:NCBI... [more]
aadac4.258e-3433.66arylacetamide deacetylase [Source:ZFIN;Acc:ZDB-GEN... [more]
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BLAST of Neutral cholesterol ester hydrolase 1 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Neutral cholesterol ester hydrolase 1 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 1
Match NameE-valueIdentityDescription
SAY18.252e-630.08Sterol deacetylase; component of the sterol acetyl... [more]
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BLAST of Neutral cholesterol ester hydrolase 1 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 3
Match NameE-valueIdentityDescription
EDO298151.951e-1126.87Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO379363.313e-1133.09Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO393764.989e-1127.59Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
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BLAST of Neutral cholesterol ester hydrolase 1 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5
Match NameE-valueIdentityDescription
aadac5.807e-3129.18arylacetamide deacetylase [Source:NCBI gene;Acc:10... [more]
ENSORLT00000016643.21.540e-3031.27neutral cholesterol ester hydrolase 1 [Source:NCBI... [more]
ENSORLT00000027750.11.540e-3031.27neutral cholesterol ester hydrolase 1 [Source:NCBI... [more]
nceh1a2.690e-2329.11neutral cholesterol ester hydrolase 1 [Source:NCBI... [more]
lipeb3.090e-2126.25lipase E, hormone sensitive type [Source:NCBI gene... [more]
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BLAST of Neutral cholesterol ester hydrolase 1 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5
Match NameE-valueIdentityDescription
SMESG000076502.11.914e-15398.58SMESG000076502.1[more]
SMESG000076513.16.936e-12787.68SMESG000076513.1[more]
SMESG000076519.16.832e-7999.15SMESG000076519.1[more]
SMESG000076505.11.456e-7898.31SMESG000076505.1[more]
SMESG000076519.14.117e-4898.68SMESG000076519.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30013846 ID=SMED30013846|Name=Neutral cholesterol ester hydrolase 1|organism=Schmidtea mediterranea sexual|type=transcript|length=1393bp
GTTTTACTGTATCAATTCATTGCTAAACTTTTGTGAAATTATTGAAAAAA
CTTATTTTATGTGACTTGACAAATGAAAAATTTGATAAAAGCCAGCCTTA
CTGTTTTAATTATTTCAGTTTTGATTTACAAATTTGTGGATTTTCGCCGG
TACGATGACTTTATCCTGCGAACGGCAGTAAATATGCATATCTTCTTAAT
GGATGCAGACATAATTTTGAGATCTATTCACATCAAAGGAGTTTATCGAT
GCTTTGAAAGTGGATTGGGAAAGCTGAATTATTACATGTCAGACAAGACA
AATTTAACTATTAAACGGAAACTATTCGACGGTGTCAATGTACTTGTTTT
CAGTCCGATTAAACGTGATAGAAAGGGGCCAGCAATCGTATATTATCATG
GCGGCGGCTGGGCAGTCATGAATCCAGAGATTTATTCTCCGTTTCTTGCG
AATTTGGCTCGGCGCCTAAATACAATGATTGTGGCAGTAGATTATAGGAA
AGCTCCTGAATATCCATATCCAGCTCCATTCAATGATGCTCTGGTTGCTA
CGAAATATTTTCTCATCAACTGTAAAGAATTCGATGTCGATCCCAATCGG
ATAGCACTGATGGGGGACAGCGCAGGAGGCAGTCTTGTTGTGTCGGTGGG
GTATCACTTGACTGCAATGAAGAGAGCTAGTAAAATTGTACACAGTCCAA
AGGTTTTGATTTCTTTGAATCCCGTATTGCAAGTTGTGGATTTCAGCACT
CCTTCGTACCGCGACAACTTGCATGACCCAATTTTGGTGAAAGCTAGAAT
GGCTCGATATTATTGCATATACGCATTCGGGGAGCAGTTATCCTGGACGG
AGTTGCGTAACTGTATTGAAGCGCTCATATCGCATAGACATTTGACAGTT
GAAGCAATCCAGAAAGTGCGGGGTCACGTAGATTGGAATAATCTCTTATC
TGGGCGCGGCTACGACAATCGACCGAGGAGTTCATTTACTCAATCAGTAA
ATCAGTTTTCCGAAAAGCTTTCTGAATTGGTGGAGAGTGTTGGATTTTCT
CCATTATCTGCCCTGAATGACAGCCAGTTACAAATTCTACCTCCCGTTTA
CGTATATGGTTCTTCAAAGGATCCTTTGAGAGATGATGCAAAAATGCTAG
TGGCCAGACTAAAACGACTAAGGTCGTTTGGAGATTACTGGGAGTTCAAA
TGTTTCCATGTTTGCTTTTTATTGGGGAGAATCGGCGTAAAAGATGAAGA
AACGTCATTGAAAGAGTTGATAAGTTTTTTTGAAAATAATGCCATTCTTT
GACTGTTTGCTGGAGACTTTCTAATATTTGCGACTTATTCTACATGTATT
GTTCATCGTTATAGAGTAAATATTTGATTGTATTCAAAAAAAA
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protein sequence of SMED30013846-orf-1

>SMED30013846-orf-1 ID=SMED30013846-orf-1|Name=SMED30013846-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=410bp
MKNLIKASLTVLIISVLIYKFVDFRRYDDFILRTAVNMHIFLMDADIILR
SIHIKGVYRCFESGLGKLNYYMSDKTNLTIKRKLFDGVNVLVFSPIKRDR
KGPAIVYYHGGGWAVMNPEIYSPFLANLARRLNTMIVAVDYRKAPEYPYP
APFNDALVATKYFLINCKEFDVDPNRIALMGDSAGGSLVVSVGYHLTAMK
RASKIVHSPKVLISLNPVLQVVDFSTPSYRDNLHDPILVKARMARYYCIY
AFGEQLSWTELRNCIEALISHRHLTVEAIQKVRGHVDWNNLLSGRGYDNR
PRSSFTQSVNQFSEKLSELVESVGFSPLSALNDSQLQILPPVYVYGSSKD
PLRDDAKMLVARLKRLRSFGDYWEFKCFHVCFLLGRIGVKDEETSLKELI
SFFENNAIL*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000034epidermis
Vocabulary: INTERPRO
TermDefinition
IPR013094AB_hydrolase_3
IPR029058AB_hydrolase
Vocabulary: biological process
TermDefinition
GO:0008152metabolic process
Vocabulary: molecular function
TermDefinition
GO:0016787hydrolase activity
GO:0052689carboxylic ester hydrolase activity
Vocabulary: cellular component
TermDefinition
GO:0016021integral component of membrane