Cathepsin L2

Overview
NameCathepsin L2
Smed IDSMED30013826
Length (bp)1161
Neoblast Clusters

Zeng et. al., 2018




▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 



 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)




Explore this single cell expression dataset with our NB Cluster Shiny App




 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of Cathepsin L2 (SMED30013826) t-SNE clustered cells

Violin plots show distribution of expression levels for Cathepsin L2 (SMED30013826) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of Cathepsin L2 (SMED30013826) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for Cathepsin L2 (SMED30013826) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017




Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020




SMED30013826

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 2

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
parenchymal cellSMED30013826SMESG000049555.1 dd_Smed_v4_1975_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
whole organism asexual adult single-cell RNA-sequencing evidence
parenchymal cellSMED30013826SMESG000049555.1 dd_Smed_v6_1975_0dd_Smed_v6PMID:29674432
Plass et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
BLAST of Cathepsin L2 vs. Ensembl Human
Match: CTSL (cathepsin L [Source:HGNC Symbol;Acc:HGNC:2537])

HSP 1 Score: 291.197 bits (744), Expect = 6.795e-96
Identity = 150/332 (45.18%), Postives = 207/332 (62.35%), Query Frame = 1
Query:   70 TYLATSFLICFFGKCFSLNLELNDQWRLFMKIYNKSYENSLHEIIRREIWEDNLKYIQKHNLDHDLDLYTFTLGINQFADLTHEEFKAIYLPGNFTNSKTGNTYLPPLNSNELPKRVDWREKGYVTNVKNQGGCGSCYSFSATGSLEGQYFRKSKKLVSLSEQQLIDCS--EKNSGCNGGWMNNAFQDVKIMGGIDSELDYPYKGKKLQCNFQRSKAITSCNGYKNIDKNENSLAIAVANEGPISVAIDASSRSFQFYKSGVYNEPNCGV-NATHAVLVVGYGTDGFDN----YWIVKNSWSTAWGIKGYIWMSKDKNNQCIIASYASFPEV 1044
            T +  +F +       + +  L  QW  +  ++N+ Y  +  E  RR +WE N+K I+ HN ++    ++FT+ +N F D+T EEF+ +         + G  +  PL   E P+ VDWREKGYVT VKNQG CGSC++FSATG+LEGQ FRK+ +L+SLSEQ L+DCS  + N GCNGG M+ AFQ V+  GG+DSE  YPY+  +  C +    ++ +  G+ +I K E +L  AVA  GPISVAIDA   SF FYK G+Y EP+C   +  H VLVVGYG +  ++    YW+VKNSW   WG+ GY+ M+KD+ N C IAS AS+P V
Sbjct:    4 TLILAAFCLGIASATLTFDHSLEAQWTKWKAMHNRLYGMN-EEGWRRAVWEKNMKMIELHNQEYREGKHSFTMAMNAFGDMTSEEFRQVMNGFQNRKPRKGKVFQEPL-FYEAPRSVDWREKGYVTPVKNQGQCGSCWAFSATGALEGQMFRKTGRLISLSEQNLVDCSGPQGNEGCNGGLMDYAFQYVQDNGGLDSEESYPYEATEESCKYNPKYSVANDTGFVDIPKQEKALMKAVATVGPISVAIDAGHESFLFYKEGIYFEPDCSSEDMDHGVLVVGYGFESTESDNNKYWLVKNSWGEEWGMGGYVKMAKDRRNHCGIASAASYPTV 333          
BLAST of Cathepsin L2 vs. Ensembl Human
Match: CTSL (cathepsin L [Source:HGNC Symbol;Acc:HGNC:2537])

HSP 1 Score: 291.197 bits (744), Expect = 6.795e-96
Identity = 150/332 (45.18%), Postives = 207/332 (62.35%), Query Frame = 1
Query:   70 TYLATSFLICFFGKCFSLNLELNDQWRLFMKIYNKSYENSLHEIIRREIWEDNLKYIQKHNLDHDLDLYTFTLGINQFADLTHEEFKAIYLPGNFTNSKTGNTYLPPLNSNELPKRVDWREKGYVTNVKNQGGCGSCYSFSATGSLEGQYFRKSKKLVSLSEQQLIDCS--EKNSGCNGGWMNNAFQDVKIMGGIDSELDYPYKGKKLQCNFQRSKAITSCNGYKNIDKNENSLAIAVANEGPISVAIDASSRSFQFYKSGVYNEPNCGV-NATHAVLVVGYGTDGFDN----YWIVKNSWSTAWGIKGYIWMSKDKNNQCIIASYASFPEV 1044
            T +  +F +       + +  L  QW  +  ++N+ Y  +  E  RR +WE N+K I+ HN ++    ++FT+ +N F D+T EEF+ +         + G  +  PL   E P+ VDWREKGYVT VKNQG CGSC++FSATG+LEGQ FRK+ +L+SLSEQ L+DCS  + N GCNGG M+ AFQ V+  GG+DSE  YPY+  +  C +    ++ +  G+ +I K E +L  AVA  GPISVAIDA   SF FYK G+Y EP+C   +  H VLVVGYG +  ++    YW+VKNSW   WG+ GY+ M+KD+ N C IAS AS+P V
Sbjct:    4 TLILAAFCLGIASATLTFDHSLEAQWTKWKAMHNRLYGMN-EEGWRRAVWEKNMKMIELHNQEYREGKHSFTMAMNAFGDMTSEEFRQVMNGFQNRKPRKGKVFQEPL-FYEAPRSVDWREKGYVTPVKNQGQCGSCWAFSATGALEGQMFRKTGRLISLSEQNLVDCSGPQGNEGCNGGLMDYAFQYVQDNGGLDSEESYPYEATEESCKYNPKYSVANDTGFVDIPKQEKALMKAVATVGPISVAIDAGHESFLFYKEGIYFEPDCSSEDMDHGVLVVGYGFESTESDNNKYWLVKNSWGEEWGMGGYVKMAKDRRNHCGIASAASYPTV 333          
BLAST of Cathepsin L2 vs. Ensembl Human
Match: CTSK (cathepsin K [Source:HGNC Symbol;Acc:HGNC:2536])

HSP 1 Score: 290.812 bits (743), Expect = 7.503e-96
Identity = 150/308 (48.70%), Postives = 198/308 (64.29%), Query Frame = 1
Query:  133 LNDQWRLFMKIYNKSYENSLHEIIRREIWEDNLKYIQKHNLDHDLDLYTFTLGINQFADLTHEEF--KAIYLPGNFTNSKTGNTYLPPLNSNELPKRVDWREKGYVTNVKNQGGCGSCYSFSATGSLEGQYFRKSKKLVSLSEQQLIDCSEKNSGCNGGWMNNAFQDVKIMGGIDSELDYPYKGKKLQCNFQRSKAITSCNGYKNI-DKNENSLAIAVANEGPISVAIDASSRSFQFYKSGVYNEPNCGV-NATHAVLVVGYGTDGFDNYWIVKNSWSTAWGIKGYIWMSKDKNNQCIIASYASFPEV 1044
            L+  W L+ K + K Y N + EI RR IWE NLKYI  HNL+  L ++T+ L +N   D+T EE   K   L    ++S++ +T   P      P  VD+R+KGYVT VKNQG CGSC++FS+ G+LEGQ  +K+ KL++LS Q L+DC  +N GC GG+M NAFQ V+   GIDSE  YPY G++  C +  +     C GY+ I + NE +L  AVA  GP+SVAIDAS  SFQFY  GVY + +C   N  HAVL VGYG    + +WI+KNSW   WG KGYI M+++KNN C IA+ ASFP++
Sbjct:   22 LDTHWELWKKTHRKQYNNKVDEISRRLIWEKNLKYISIHNLEASLGVHTYELAMNHLGDMTSEEVVQKMTGLKVPLSHSRSNDTLYIPEWEGRAPDSVDYRKKGYVTPVKNQGQCGSCWAFSSVGALEGQLKKKTGKLLNLSPQNLVDCVSENDGCGGGYMTNAFQYVQKNRGIDSEDAYPYVGQEESCMYNPTGKAAKCRGYREIPEGNEKALKRAVARVGPVSVAIDASLTSFQFYSKGVYYDESCNSDNLNHAVLAVGYGIQKGNKHWIIKNSWGENWGNKGYILMARNKNNACGIANLASFPKM 329          
BLAST of Cathepsin L2 vs. Ensembl Human
Match: CTSV (cathepsin V [Source:HGNC Symbol;Acc:HGNC:2538])

HSP 1 Score: 279.641 bits (714), Expect = 1.978e-91
Identity = 153/314 (48.73%), Postives = 202/314 (64.33%), Query Frame = 1
Query:  133 LNDQWRLFMKIYNKSYENSLHEIIRREIWEDNLKYIQKHNLDHDLDLYTFTLGINQFADLTHEEFKAIYLPGNFTNSK--TGNTYLPPLNSNELPKRVDWREKGYVTNVKNQGGCGSCYSFSATGSLEGQYFRKSKKLVSLSEQQLIDCS--EKNSGCNGGWMNNAFQDVKIMGGIDSELDYPYKGKKLQCNFQRSKAITSCNGYKNIDKN-ENSLAIAVANEGPISVAIDASSRSFQFYKSGVYNEPNCGV-NATHAVLVVGYGTDGFDN----YWIVKNSWSTAWGIKGYIWMSKDKNNQCIIASYASFPEV 1044
            L+ +W  +   + + Y  +  E  RR +WE N+K I+ HN ++    + FT+ +N F D+T+EEF+ +   G F N K   G  +  PL   +LPK VDWR+KGYVT VKNQ  CGSC++FSATG+LEGQ FRK+ KLVSLSEQ L+DCS  + N GCNGG+M  AFQ VK  GG+DSE  YPY      C ++   ++ +  G+  +    E +L  AVA  GPISVA+DA   SFQFYKSG+Y EP+C   N  H VLVVGYG +G ++    YW+VKNSW   WG  GY+ ++KDKNN C IA+ AS+P V
Sbjct:   25 LDTKWYQWKATHRRLY-GANEEGWRRAVWEKNMKMIELHNGEYSQGKHGFTMAMNAFGDMTNEEFRQMM--GCFRNQKFRKGKVFREPLFL-DLPKSVDWRKKGYVTPVKNQKQCGSCWAFSATGALEGQMFRKTGKLVSLSEQNLVDCSRPQGNQGCNGGFMARAFQYVKENGGLDSEESYPYVAVDEICKYRPENSVANDTGFTVVAPGKEKALMKAVATVGPISVAMDAGHSSFQFYKSGIYFEPDCSSKNLDHGVLVVGYGFEGANSNNSKYWLVKNSWGPEWGSNGYVKIAKDKNNHCGIATAASYPNV 334          
BLAST of Cathepsin L2 vs. Ensembl Human
Match: CTSV (cathepsin V [Source:HGNC Symbol;Acc:HGNC:2538])

HSP 1 Score: 279.641 bits (714), Expect = 1.978e-91
Identity = 153/314 (48.73%), Postives = 202/314 (64.33%), Query Frame = 1
Query:  133 LNDQWRLFMKIYNKSYENSLHEIIRREIWEDNLKYIQKHNLDHDLDLYTFTLGINQFADLTHEEFKAIYLPGNFTNSK--TGNTYLPPLNSNELPKRVDWREKGYVTNVKNQGGCGSCYSFSATGSLEGQYFRKSKKLVSLSEQQLIDCS--EKNSGCNGGWMNNAFQDVKIMGGIDSELDYPYKGKKLQCNFQRSKAITSCNGYKNIDKN-ENSLAIAVANEGPISVAIDASSRSFQFYKSGVYNEPNCGV-NATHAVLVVGYGTDGFDN----YWIVKNSWSTAWGIKGYIWMSKDKNNQCIIASYASFPEV 1044
            L+ +W  +   + + Y  +  E  RR +WE N+K I+ HN ++    + FT+ +N F D+T+EEF+ +   G F N K   G  +  PL   +LPK VDWR+KGYVT VKNQ  CGSC++FSATG+LEGQ FRK+ KLVSLSEQ L+DCS  + N GCNGG+M  AFQ VK  GG+DSE  YPY      C ++   ++ +  G+  +    E +L  AVA  GPISVA+DA   SFQFYKSG+Y EP+C   N  H VLVVGYG +G ++    YW+VKNSW   WG  GY+ ++KDKNN C IA+ AS+P V
Sbjct:   25 LDTKWYQWKATHRRLY-GANEEGWRRAVWEKNMKMIELHNGEYSQGKHGFTMAMNAFGDMTNEEFRQMM--GCFRNQKFRKGKVFREPLFL-DLPKSVDWRKKGYVTPVKNQKQCGSCWAFSATGALEGQMFRKTGKLVSLSEQNLVDCSRPQGNQGCNGGFMARAFQYVKENGGLDSEESYPYVAVDEICKYRPENSVANDTGFTVVAPGKEKALMKAVATVGPISVAMDAGHSSFQFYKSGIYFEPDCSSKNLDHGVLVVGYGFEGANSNNSKYWLVKNSWGPEWGSNGYVKIAKDKNNHCGIATAASYPNV 334          
BLAST of Cathepsin L2 vs. Ensembl Celegans
Match: cpl-1 (CathePsin L family [Source:UniProtKB/TrEMBL;Acc:H9G333])

HSP 1 Score: 266.929 bits (681), Expect = 8.277e-87
Identity = 141/311 (45.34%), Postives = 199/311 (63.99%), Query Frame = 1
Query:  139 DQWRLFMKIYNKSYENSLHEIIRREIWEDNLKYIQKHNLDHDLDLYTFTLGINQFADLTHEEFKAI----YLPGNFTNSKTGNTYLPPLNSNELPKRVDWREKGYVTNVKNQGGCGSCYSFSATGSLEGQYFRKSKKLVSLSEQQLIDCSEK--NSGCNGGWMNNAFQDVKIMGGIDSELDYPYKGKKLQCNFQRSKAITSCNGYKNI-DKNENSLAIAVANEGPISVAIDASSRSFQFYKSGVYNEPNCGVNA-THAVLVVGYGTDG-FDNYWIVKNSWSTAWGIKGYIWMSKDKNNQCIIASYASFPEV 1044
            ++W  + + ++K Y  S  E    E +  N+ +I+ HN DH L   TF +G+N  ADL   +++ +     L G+ +  K  +++L P N  ++P  VDWR+   VT+VKNQG CGSC++FSATG+LEGQ+ RK  +LVSLSEQ L+DCS K  N GCNGG M+ AF+ ++   G+D+E  YPYKG+ ++C+F +        GY +  + +E  L IAVA +GPIS+AIDA  RSFQ YK GVY +  C      H VL+VGYGTD    +YWIVKNSW   WG KGYI +++++NN C +A+ AS+P V
Sbjct:   30 EKWDDYKEDFDKEYSES-EEQTYMEAFVKNMIHIENHNRDHRLGRKTFEMGLNHIADLPFSQYRKLNGYRRLFGD-SRIKNSSSFLAPFNV-QVPDEVDWRDTHLVTDVKNQGMCGSCWAFSATGALEGQHARKLGQLVSLSEQNLVDCSTKYGNHGCNGGLMDQAFEYIRDNHGVDTEESYPYKGRDMKCHFNKKTVGADDKGYVDTPEGDEEQLKIAVATQGPISIAIDAGHRSFQLYKKGVYYDEECSSEELDHGVLLVGYGTDPEHGDYWIVKNSWGAGWGEKGYIRIARNRNNHCGVATKASYPLV 337          
BLAST of Cathepsin L2 vs. Ensembl Celegans
Match: cpl-1 (CathePsin L family [Source:UniProtKB/TrEMBL;Acc:H9G333])

HSP 1 Score: 205.682 bits (522), Expect = 6.736e-65
Identity = 103/197 (52.28%), Postives = 136/197 (69.04%), Query Frame = 1
Query:  469 CGSCYSFSATGSLEGQYFRKSKKLVSLSEQQLIDCSEK--NSGCNGGWMNNAFQDVKIMGGIDSELDYPYKGKKLQCNFQRSKAITSCNGYKNI-DKNENSLAIAVANEGPISVAIDASSRSFQFYKSGVYNEPNCGVNA-THAVLVVGYGTDG-FDNYWIVKNSWSTAWGIKGYIWMSKDKNNQCIIASYASFPEV 1044
            CGSC++FSATG+LEGQ+ RK  +LVSLSEQ L+DCS K  N GCNGG M+ AF+ ++   G+D+E  YPYKG+ ++C+F +        GY +  + +E  L IAVA +GPIS+AIDA  RSFQ YK GVY +  C      H VL+VGYGTD    +YWIVKNSW   WG KGYI +++++NN C +A+ AS+P V
Sbjct:    2 CGSCWAFSATGALEGQHARKLGQLVSLSEQNLVDCSTKYGNHGCNGGLMDQAFEYIRDNHGVDTEESYPYKGRDMKCHFNKKTVGADDKGYVDTPEGDEEQLKIAVATQGPISIAIDAGHRSFQLYKKGVYYDEECSSEELDHGVLLVGYGTDPEHGDYWIVKNSWGAGWGEKGYIRIARNRNNHCGVATKASYPLV 198          
BLAST of Cathepsin L2 vs. Ensembl Celegans
Match: cpl-1 (CathePsin L family [Source:UniProtKB/TrEMBL;Acc:H9G333])

HSP 1 Score: 205.682 bits (522), Expect = 6.736e-65
Identity = 103/197 (52.28%), Postives = 136/197 (69.04%), Query Frame = 1
Query:  469 CGSCYSFSATGSLEGQYFRKSKKLVSLSEQQLIDCSEK--NSGCNGGWMNNAFQDVKIMGGIDSELDYPYKGKKLQCNFQRSKAITSCNGYKNI-DKNENSLAIAVANEGPISVAIDASSRSFQFYKSGVYNEPNCGVNA-THAVLVVGYGTDG-FDNYWIVKNSWSTAWGIKGYIWMSKDKNNQCIIASYASFPEV 1044
            CGSC++FSATG+LEGQ+ RK  +LVSLSEQ L+DCS K  N GCNGG M+ AF+ ++   G+D+E  YPYKG+ ++C+F +        GY +  + +E  L IAVA +GPIS+AIDA  RSFQ YK GVY +  C      H VL+VGYGTD    +YWIVKNSW   WG KGYI +++++NN C +A+ AS+P V
Sbjct:    2 CGSCWAFSATGALEGQHARKLGQLVSLSEQNLVDCSTKYGNHGCNGGLMDQAFEYIRDNHGVDTEESYPYKGRDMKCHFNKKTVGADDKGYVDTPEGDEEQLKIAVATQGPISIAIDAGHRSFQLYKKGVYYDEECSSEELDHGVLLVGYGTDPEHGDYWIVKNSWGAGWGEKGYIRIARNRNNHCGVATKASYPLV 198          
BLAST of Cathepsin L2 vs. Ensembl Celegans
Match: tag-196 (pep chromosome:WBcel235:V:8594914:8597500:1 gene:WBGene00007055.1 transcript:F41E6.6.2 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:tag-196)

HSP 1 Score: 201.06 bits (510), Expect = 1.018e-59
Identity = 112/295 (37.97%), Postives = 162/295 (54.92%), Query Frame = 1
Query:  154 FMKIYNKSYENSLHEIIRREIWEDNLKYIQKHNLDHDLDLYTFTLGINQFADLTHEEFKAIYLPGNF------TNSKTGNTYLPPLNSNELPKRVDWREKGYVTNVKNQGGCGSCYSFSATGSLEGQYFRKSKKLVSLSEQQLIDCSEKNSGCNGGWMNNAFQDVKIMGGIDSELDYPYKGKKLQCNFQRSKAITSCNGYKNIDKNENSLAIAVANEGPISVAIDASSRSFQFYKSGVYN------EPNCGVNATHAVLVVGYGTDGFDNYWIVKNSWSTAWGIKGYIWMSKDKN 1002
            F+  + K Y N    + R  +++ N K I++   +   +  T   G  +F+D+T  EFK I LP  +              +   +N  +LP+  DWREKG VT VKNQG CGSC++FS TG++EG +F    KLVSLSEQ+L+DC   + GCNGG  +NA++++  MGG++ E  YPY G+   C+  R       NG   +  +E  +   +  +GPIS+ ++A+  + QFY+ GV +      EP       H VL+VGYG DG   YWIVKNSW   WG  GY  + + KN
Sbjct:  177 FVDRHEKKYTNKREVLKRFRVFKKNAKVIRELQKN---EQGTAVYGFTKFSDMTTMEFKKIMLPYQWEQPVYPMEQANFEKHDVTINEEDLPESFDWREKGAVTQVKNQGNCGSCWAFSTTGNVEGAWFIAKNKLVSLSEQELVDCDSMDQGCNGGLPSNAYKEIIRMGGLEPEDAYPYDGRGETCHLVRKDIAVYINGSVELPHDEVEMQKWLVTKGPISIGLNAN--TLQFYRHGVVHPFKIFCEP---FMLNHGVLIVGYGKDGRKPYWIVKNSWGPNWGEAGYFKLYRGKN 463          
BLAST of Cathepsin L2 vs. Ensembl Celegans
Match: tag-196 (pep chromosome:WBcel235:V:8594914:8597469:1 gene:WBGene00007055.1 transcript:F41E6.6.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:tag-196)

HSP 1 Score: 201.06 bits (510), Expect = 1.018e-59
Identity = 112/295 (37.97%), Postives = 162/295 (54.92%), Query Frame = 1
Query:  154 FMKIYNKSYENSLHEIIRREIWEDNLKYIQKHNLDHDLDLYTFTLGINQFADLTHEEFKAIYLPGNF------TNSKTGNTYLPPLNSNELPKRVDWREKGYVTNVKNQGGCGSCYSFSATGSLEGQYFRKSKKLVSLSEQQLIDCSEKNSGCNGGWMNNAFQDVKIMGGIDSELDYPYKGKKLQCNFQRSKAITSCNGYKNIDKNENSLAIAVANEGPISVAIDASSRSFQFYKSGVYN------EPNCGVNATHAVLVVGYGTDGFDNYWIVKNSWSTAWGIKGYIWMSKDKN 1002
            F+  + K Y N    + R  +++ N K I++   +   +  T   G  +F+D+T  EFK I LP  +              +   +N  +LP+  DWREKG VT VKNQG CGSC++FS TG++EG +F    KLVSLSEQ+L+DC   + GCNGG  +NA++++  MGG++ E  YPY G+   C+  R       NG   +  +E  +   +  +GPIS+ ++A+  + QFY+ GV +      EP       H VL+VGYG DG   YWIVKNSW   WG  GY  + + KN
Sbjct:  177 FVDRHEKKYTNKREVLKRFRVFKKNAKVIRELQKN---EQGTAVYGFTKFSDMTTMEFKKIMLPYQWEQPVYPMEQANFEKHDVTINEEDLPESFDWREKGAVTQVKNQGNCGSCWAFSTTGNVEGAWFIAKNKLVSLSEQELVDCDSMDQGCNGGLPSNAYKEIIRMGGLEPEDAYPYDGRGETCHLVRKDIAVYINGSVELPHDEVEMQKWLVTKGPISIGLNAN--TLQFYRHGVVHPFKIFCEP---FMLNHGVLIVGYGKDGRKPYWIVKNSWGPNWGEAGYFKLYRGKN 463          
BLAST of Cathepsin L2 vs. Ensembl Fly
Match: Cp1 (gene:FBgn0013770 transcript:FBtr0087592)

HSP 1 Score: 285.804 bits (730), Expect = 4.267e-94
Identity = 153/316 (48.42%), Postives = 203/316 (64.24%), Query Frame = 1
Query:  139 DQWRLFMKIYNKSYENSLHEIIRREIWEDNLKYIQKHNLDHDLDLYTFTLGINQFADLTHEEFKAIYLPGNFTNSKT---------GNTYLPPLNSNELPKRVDWREKGYVTNVKNQGGCGSCYSFSATGSLEGQYFRKSKKLVSLSEQQLIDCSEK--NSGCNGGWMNNAFQDVKIMGGIDSELDYPYKGKKLQCNFQRSKAITSCNGYKNIDK-NENSLAIAVANEGPISVAIDASSRSFQFYKSGVYNEPNCGV-NATHAVLVVGYGTD-GFDNYWIVKNSWSTAWGIKGYIWMSKDKNNQCIIASYASFPEV 1044
            ++W  F   + K+Y++   E  R +I+ +N   I KHN        +F L +N++ADL H EF+ +    N+T  K          G T++ P +   LPK VDWR KG VT VK+QG CGSC++FS+TG+LEGQ+FRKS  LVSLSEQ L+DCS K  N+GCNGG M+NAF+ +K  GGID+E  YPY+     C+F +     +  G+ +I + +E  +A AVA  GP+SVAIDAS  SFQFY  GVYNEP C   N  H VLVVG+GTD   ++YW+VKNSW T WG KG+I M ++K NQC IAS +S+P V
Sbjct:   27 EEWHTFKLEHRKNYQDETEERFRLKIFNENKHKIAKHNQRFAEGKVSFKLAVNKYADLLHHEFRQLMNGFNYTLHKQLRAADESFKGVTFISPAHVT-LPKSVDWRTKGAVTAVKDQGHCGSCWAFSSTGALEGQHFRKSGVLVSLSEQNLVDCSTKYGNNGCNGGLMDNAFRYIKDNGGIDTEKSYPYEAIDDSCHFNKGTVGATDRGFTDIPQGDEKKMAEAVATVGPVSVAIDASHESFQFYSEGVYNEPQCDAQNLDHGVLVVGFGTDESGEDYWLVKNSWGTTWGDKGFIKMLRNKENQCGIASASSYPLV 341          
BLAST of Cathepsin L2 vs. Ensembl Fly
Match: Cp1 (gene:FBgn0013770 transcript:FBtr0087593)

HSP 1 Score: 286.189 bits (731), Expect = 8.819e-94
Identity = 153/316 (48.42%), Postives = 203/316 (64.24%), Query Frame = 1
Query:  139 DQWRLFMKIYNKSYENSLHEIIRREIWEDNLKYIQKHNLDHDLDLYTFTLGINQFADLTHEEFKAIYLPGNFTNSKT---------GNTYLPPLNSNELPKRVDWREKGYVTNVKNQGGCGSCYSFSATGSLEGQYFRKSKKLVSLSEQQLIDCSEK--NSGCNGGWMNNAFQDVKIMGGIDSELDYPYKGKKLQCNFQRSKAITSCNGYKNIDK-NENSLAIAVANEGPISVAIDASSRSFQFYKSGVYNEPNCGV-NATHAVLVVGYGTD-GFDNYWIVKNSWSTAWGIKGYIWMSKDKNNQCIIASYASFPEV 1044
            ++W  F   + K+Y++   E  R +I+ +N   I KHN        +F L +N++ADL H EF+ +    N+T  K          G T++ P +   LPK VDWR KG VT VK+QG CGSC++FS+TG+LEGQ+FRKS  LVSLSEQ L+DCS K  N+GCNGG M+NAF+ +K  GGID+E  YPY+     C+F +     +  G+ +I + +E  +A AVA  GP+SVAIDAS  SFQFY  GVYNEP C   N  H VLVVG+GTD   ++YW+VKNSW T WG KG+I M ++K NQC IAS +S+P V
Sbjct:   57 EEWHTFKLEHRKNYQDETEERFRLKIFNENKHKIAKHNQRFAEGKVSFKLAVNKYADLLHHEFRQLMNGFNYTLHKQLRAADESFKGVTFISPAHVT-LPKSVDWRTKGAVTAVKDQGHCGSCWAFSSTGALEGQHFRKSGVLVSLSEQNLVDCSTKYGNNGCNGGLMDNAFRYIKDNGGIDTEKSYPYEAIDDSCHFNKGTVGATDRGFTDIPQGDEKKMAEAVATVGPVSVAIDASHESFQFYSEGVYNEPQCDAQNLDHGVLVVGFGTDESGEDYWLVKNSWGTTWGDKGFIKMLRNKENQCGIASASSYPLV 371          
BLAST of Cathepsin L2 vs. Ensembl Fly
Match: Cp1 (gene:FBgn0013770 transcript:FBtr0339955)

HSP 1 Score: 281.952 bits (720), Expect = 1.300e-92
Identity = 154/318 (48.43%), Postives = 205/318 (64.47%), Query Frame = 1
Query:  133 LNDQWRLFMKIYNKSYENSLHEIIRREIWEDNLKYIQKHNLDHDLDLYTFTLGINQFADLTHEEFKAIYLPGNFTNSKT---------GNTYLPPLNSNELPKRVDWREKGYVTNVKNQGGCGSCYSFSATGSLEGQYFRKSKKLVSLSEQQLIDCSEK--NSGCNGGWMNNAFQDVKIMGGIDSELDYPYKGKKLQCNFQRSKAITSCNGYKNIDK-NENSLAIAVANEGPISVAIDASSRSFQFYKSGVYNEPNCGV-NATHAVLVVGYGTD-GFDNYWIVKNSWSTAWGIKGYIWMSKDKNNQCIIASYASFPEV 1044
            L +  RL ++ + K+Y++   E  R +I+ +N   I KHN        +F L +N++ADL H EF+ +    N+T  K          G T++ P +   LPK VDWR KG VT VK+QG CGSC++FS+TG+LEGQ+FRKS  LVSLSEQ L+DCS K  N+GCNGG M+NAF+ +K  GGID+E  YPY+     C+F +     +  G+ +I + +E  +A AVA  GP+SVAIDAS  SFQFY  GVYNEP C   N  H VLVVG+GTD   ++YW+VKNSW T WG KG+I M ++K NQC IAS +S+P V
Sbjct:   23 LQNLLRLVLE-HRKNYQDETEERFRLKIFNENKHKIAKHNQRFAEGKVSFKLAVNKYADLLHHEFRQLMNGFNYTLHKQLRAADESFKGVTFISPAHVT-LPKSVDWRTKGAVTAVKDQGHCGSCWAFSSTGALEGQHFRKSGVLVSLSEQNLVDCSTKYGNNGCNGGLMDNAFRYIKDNGGIDTEKSYPYEAIDDSCHFNKGTVGATDRGFTDIPQGDEKKMAEAVATVGPVSVAIDASHESFQFYSEGVYNEPQCDAQNLDHGVLVVGFGTDESGEDYWLVKNSWGTTWGDKGFIKMLRNKENQCGIASASSYPLV 338          
BLAST of Cathepsin L2 vs. Ensembl Fly
Match: Cp1 (gene:FBgn0013770 transcript:FBtr0304021)

HSP 1 Score: 248.825 bits (634), Expect = 7.018e-81
Identity = 134/256 (52.34%), Postives = 172/256 (67.19%), Query Frame = 1
Query:  292 INQFADLTHEEFKAIYLPGNFTNSKTGNTYLPPLNSNELPKRVDWREKGYVTNVKNQGGCGSCYSFSATGSLEGQYFRKSKKLVSLSEQQLIDCSEK--NSGCNGGWMNNAFQDVKIMGGIDSELDYPYKGKKLQCNFQRSKAITSCNGYKNIDK-NENSLAIAVANEGPISVAIDASSRSFQFYKSGVYNEPNCGV-NATHAVLVVGYGTD-GFDNYWIVKNSWSTAWGIKGYIWMSKDKNNQCIIASYASFPEV 1044
            +N F    H++ +A         S  G T++ P +   LPK VDWR KG VT VK+QG CGSC++FS+TG+LEGQ+FRKS  LVSLSEQ L+DCS K  N+GCNGG M+NAF+ +K  GGID+E  YPY+     C+F +     +  G+ +I + +E  +A AVA  GP+SVAIDAS  SFQFY  GVYNEP C   N  H VLVVG+GTD   ++YW+VKNSW T WG KG+I M ++K NQC IAS +S+P V
Sbjct:    1 MNGFNYTLHKQLRAA------DESFKGVTFISPAHVT-LPKSVDWRTKGAVTAVKDQGHCGSCWAFSSTGALEGQHFRKSGVLVSLSEQNLVDCSTKYGNNGCNGGLMDNAFRYIKDNGGIDTEKSYPYEAIDDSCHFNKGTVGATDRGFTDIPQGDEKKMAEAVATVGPVSVAIDASHESFQFYSEGVYNEPQCDAQNLDHGVLVVGFGTDESGEDYWLVKNSWGTTWGDKGFIKMLRNKENQCGIASASSYPLV 249          
BLAST of Cathepsin L2 vs. Ensembl Fly
Match: CG12163 (gene:FBgn0260462 transcript:FBtr0078822)

HSP 1 Score: 204.142 bits (518), Expect = 7.541e-61
Identity = 117/305 (38.36%), Postives = 177/305 (58.03%), Query Frame = 1
Query:  154 FMKIYNKSYENSLHEIIRREIWEDNLKYIQKHNLDHDLDLYTFTLGINQFADLTHEEFKAIYLPGNFTNSKT--GNTYLPPLNSNELPKRVDWREKGYVTNVKNQGGCGSCYSFSATGSLEGQYFRKSKKLVSLSEQQLIDCSEKNSGCNGGWMNNAFQDVKIMGGIDSELDYPYKGKKLQCNFQRSKAITSCNGYKNIDK-NENSLAIAVANEGPISVAIDASSRSFQFYKSGVYN--EPNCG-VNATHAVLVVGYGTDGFDN------YWIVKNSWSTAWGIKGYIWMSKDKNNQCIIASYAS 1032
            F   + + Y ++    +R  I+  NLK I++ N +   ++ +   GI +FAD+T  E+K          +K   G+  + P    ELPK  DWR+K  VT VKNQG CGSC++FS TG++EG Y  K+ +L   SEQ+L+DC   +S CNGG M+NA++ +K +GG++ E +YPYK KK QC+F R+ +     G+ ++ K NE ++   +   GPIS+ I+A+  + QFY+ GV +  +  C   N  H VLVVGYG   + N      YWIVKNSW   WG +GY  + +  +N C ++  A+
Sbjct:  172 FQVRFGRRYVSTAERQMRLRIFRQNLKTIEELNAN---EMGSAKYGITEFADMTSSEYKERTGLWQRDEAKATGGSAAVVPAYHGELPKEFDWRQKDAVTQVKNQGSCGSCWAFSVTGNIEGLYAVKTGELKEFSEQELLDCDTTDSACNGGLMDNAYKAIKDIGGLEYEAEYPYKAKKNQCHFNRTLSHVQVAGFVDLPKGNETAMQEWLLANGPISIGINAN--AMQFYRGGVSHPWKALCSKKNLDHGVLVVGYGVSDYPNFHKTLPYWIVKNSWGPRWGEQGYYRVYRG-DNTCGVSEMAT 470          
BLAST of Cathepsin L2 vs. Ensembl Zebrafish
Match: ctsla (cathepsin La [Source:ZFIN;Acc:ZDB-GENE-030131-106])

HSP 1 Score: 304.294 bits (778), Expect = 2.667e-101
Identity = 168/342 (49.12%), Postives = 221/342 (64.62%), Query Frame = 1
Query:   64 MNTYLATSFLICFFG--KCFSLNLELNDQWRLFMKIYNKSYENSLHEIIRREIWEDNLKYIQKHNLDHDLDLYTFTLGINQFADLTHEEFKAIYLPGNFTNSK----TGNTYLPPLNSNELPKRVDWREKGYVTNVKNQGGCGSCYSFSATGSLEGQYFRKSKKLVSLSEQQLIDCS--EKNSGCNGGWMNNAFQDVKIMGGIDSELDYPYKGKKLQ-CNFQRSKAITSCNGYKNIDKN-ENSLAIAVANEGPISVAIDASSRSFQFYKSGVYNEPNCGVNA-THAVLVVGYGTDGFD----NYWIVKNSWSTAWGIKGYIWMSKDKNNQCIIASYASFPEV 1044
            M  +LA +F +C        +L+ +LND W  + K ++K Y ++  E  RR IWE NLK I+ HNL+H + ++T+ LG+N F D+THEEF+ +     F + K     G+ ++ P N  E+P ++DWREKGYVT VK+QG CGSC++FS TG+LEGQ FRK+ KLVSLSEQ L+DCS  E N GCNGG M+ AFQ VK   G+DSE  YPY G   Q C+F    +  +  G+ +I    E +L  A+A  GP+SVAIDA   SFQFY+SG+Y E  C      H VL VGYG +G D     YWIVKNSWS  WG KGYI+M+KD++N C IA+ AS+P V
Sbjct:    1 MRVFLA-AFTLCLSAVFAAPTLDQQLNDHWDQWKKWHSKKY-HATEEGWRRIIWEKNLKKIEMHNLEHSMGIHTYRLGMNHFGDMTHEEFRQVM--NGFKHKKDRRFRGSLFMEP-NFIEVPNKLDWREKGYVTPVKDQGECGSCWAFSTTGALEGQMFRKTGKLVSLSEQNLVDCSRPEGNEGCNGGLMDQAFQYVKDQNGLDSEESYPYLGTDDQPCHFDPKNSAANDTGFVDIPSGKERALMKAIAAVGPVSVAIDAGHESFQFYQSGIYYEKECSSEELDHGVLAVGYGFEGEDVDGKKYWIVKNSWSENWGDKGYIYMAKDRHNHCGIATAASYPLV 337          
BLAST of Cathepsin L2 vs. Ensembl Zebrafish
Match: ctsla (cathepsin La [Source:ZFIN;Acc:ZDB-GENE-030131-106])

HSP 1 Score: 304.294 bits (778), Expect = 2.667e-101
Identity = 168/342 (49.12%), Postives = 221/342 (64.62%), Query Frame = 1
Query:   64 MNTYLATSFLICFFG--KCFSLNLELNDQWRLFMKIYNKSYENSLHEIIRREIWEDNLKYIQKHNLDHDLDLYTFTLGINQFADLTHEEFKAIYLPGNFTNSK----TGNTYLPPLNSNELPKRVDWREKGYVTNVKNQGGCGSCYSFSATGSLEGQYFRKSKKLVSLSEQQLIDCS--EKNSGCNGGWMNNAFQDVKIMGGIDSELDYPYKGKKLQ-CNFQRSKAITSCNGYKNIDKN-ENSLAIAVANEGPISVAIDASSRSFQFYKSGVYNEPNCGVNA-THAVLVVGYGTDGFD----NYWIVKNSWSTAWGIKGYIWMSKDKNNQCIIASYASFPEV 1044
            M  +LA +F +C        +L+ +LND W  + K ++K Y ++  E  RR IWE NLK I+ HNL+H + ++T+ LG+N F D+THEEF+ +     F + K     G+ ++ P N  E+P ++DWREKGYVT VK+QG CGSC++FS TG+LEGQ FRK+ KLVSLSEQ L+DCS  E N GCNGG M+ AFQ VK   G+DSE  YPY G   Q C+F    +  +  G+ +I    E +L  A+A  GP+SVAIDA   SFQFY+SG+Y E  C      H VL VGYG +G D     YWIVKNSWS  WG KGYI+M+KD++N C IA+ AS+P V
Sbjct:    1 MRVFLA-AFTLCLSAVFAAPTLDQQLNDHWDQWKKWHSKKY-HATEEGWRRIIWEKNLKKIEMHNLEHSMGIHTYRLGMNHFGDMTHEEFRQVM--NGFKHKKDRRFRGSLFMEP-NFIEVPNKLDWREKGYVTPVKDQGECGSCWAFSTTGALEGQMFRKTGKLVSLSEQNLVDCSRPEGNEGCNGGLMDQAFQYVKDQNGLDSEESYPYLGTDDQPCHFDPKNSAANDTGFVDIPSGKERALMKAIAAVGPVSVAIDAGHESFQFYQSGIYYEKECSSEELDHGVLAVGYGFEGEDVDGKKYWIVKNSWSENWGDKGYIYMAKDRHNHCGIATAASYPLV 337          
BLAST of Cathepsin L2 vs. Ensembl Zebrafish
Match: si:dkey-239j18.2 (si:dkey-239j18.2 [Source:ZFIN;Acc:ZDB-GENE-121214-52])

HSP 1 Score: 297.745 bits (761), Expect = 9.699e-99
Identity = 161/335 (48.06%), Postives = 216/335 (64.48%), Query Frame = 1
Query:   64 MNTYLATSFLICFFGKCFSLNLELNDQWRLFMKIYNKSYENSLHEIIRREIWEDNLKYIQKHNLDHDLDLYTFTLGINQFADLTHEEFKAIYLPGNFTNSKT--GNTYLPPLNSNELPKRVDWREKGYVTNVKNQGGCGSCYSFSATGSLEGQYFRKSKKLVSLSEQQLIDCSEK--NSGCNGGWMNNAFQDVKIMGGIDSELDYPYKGK-KLQCNFQRSKAITSCNGYKNIDK-NENSLAIAVANEGPISVAIDASSRSFQFYKSGVYNEPNCGVNATHAVLVVGYGTDGFD----NYWIVKNSWSTAWGIKGYIWMSKDKNNQCIIASYASFP 1038
            M   L T ++   F    S++++L+D W  +   + KSY   + E+ RR IWE+NL+ I++HN ++ L  +TF +G+NQF D+T+EEF+          ++T  G  ++ P      P++VDWR++GYVT VK+Q  CGSC+SFS+TG+LEGQ FRK+ KL+S+SEQ L+DCS    N GCNGG M+ AFQ VK   G+DSE  YPY  +  L C +     +    G+ +I K NE +L  AVA  GP+SVAIDAS +S QFY+SG+Y E  C     HAVLVVGYG  G D     YWIVKNSWS  WG KGYI+M+KDKNN C IA+ AS+P
Sbjct:    2 MFALLVTLYISAVFAAP-SIDIQLDDHWNSWKSQHGKSYHEDV-EVGRRMIWEENLRKIEQHNFEYSLGNHTFKMGMNQFGDMTNEEFRQAMNGYKHDPNRTSQGPLFMEP-KFFAAPQQVDWRQRGYVTPVKDQKQCGSCWSFSSTGALEGQLFRKTGKLISMSEQNLVDCSRPHGNQGCNGGLMDQAFQYVKENKGLDSEQSYPYLARDDLPCRYDPRFNVAKITGFVDIPKGNELALMNAVAAVGPVSVAIDASHQSLQFYQSGIYYERACTSQLDHAVLVVGYGYQGADVAGNRYWIVKNSWSDKWGDKGYIYMAKDKNNHCGIATMASYP 333          
BLAST of Cathepsin L2 vs. Ensembl Zebrafish
Match: si:dkey-239j18.2 (si:dkey-239j18.2 [Source:ZFIN;Acc:ZDB-GENE-121214-52])

HSP 1 Score: 297.745 bits (761), Expect = 9.699e-99
Identity = 161/335 (48.06%), Postives = 216/335 (64.48%), Query Frame = 1
Query:   64 MNTYLATSFLICFFGKCFSLNLELNDQWRLFMKIYNKSYENSLHEIIRREIWEDNLKYIQKHNLDHDLDLYTFTLGINQFADLTHEEFKAIYLPGNFTNSKT--GNTYLPPLNSNELPKRVDWREKGYVTNVKNQGGCGSCYSFSATGSLEGQYFRKSKKLVSLSEQQLIDCSEK--NSGCNGGWMNNAFQDVKIMGGIDSELDYPYKGK-KLQCNFQRSKAITSCNGYKNIDK-NENSLAIAVANEGPISVAIDASSRSFQFYKSGVYNEPNCGVNATHAVLVVGYGTDGFD----NYWIVKNSWSTAWGIKGYIWMSKDKNNQCIIASYASFP 1038
            M   L T ++   F    S++++L+D W  +   + KSY   + E+ RR IWE+NL+ I++HN ++ L  +TF +G+NQF D+T+EEF+          ++T  G  ++ P      P++VDWR++GYVT VK+Q  CGSC+SFS+TG+LEGQ FRK+ KL+S+SEQ L+DCS    N GCNGG M+ AFQ VK   G+DSE  YPY  +  L C +     +    G+ +I K NE +L  AVA  GP+SVAIDAS +S QFY+SG+Y E  C     HAVLVVGYG  G D     YWIVKNSWS  WG KGYI+M+KDKNN C IA+ AS+P
Sbjct:    2 MFALLVTLYISAVFAAP-SIDIQLDDHWNSWKSQHGKSYHEDV-EVGRRMIWEENLRKIEQHNFEYSLGNHTFKMGMNQFGDMTNEEFRQAMNGYKHDPNRTSQGPLFMEP-KFFAAPQQVDWRQRGYVTPVKDQKQCGSCWSFSSTGALEGQLFRKTGKLISMSEQNLVDCSRPHGNQGCNGGLMDQAFQYVKENKGLDSEQSYPYLARDDLPCRYDPRFNVAKITGFVDIPKGNELALMNAVAAVGPVSVAIDASHQSLQFYQSGIYYERACTSQLDHAVLVVGYGYQGADVAGNRYWIVKNSWSDKWGDKGYIYMAKDKNNHCGIATMASYP 333          
BLAST of Cathepsin L2 vs. Ensembl Zebrafish
Match: zgc:174855 (zgc:174855 [Source:ZFIN;Acc:ZDB-GENE-071004-74])

HSP 1 Score: 295.434 bits (755), Expect = 8.976e-98
Identity = 155/317 (48.90%), Postives = 211/317 (66.56%), Query Frame = 1
Query:  118 SLNLELNDQWRLFMKIYNKSYENSLHEIIRREIWEDNLKYIQKHNLDHDLDLYTFTLGINQFADLTHEEFKAIY--LPGNFTNSKTGNTYLPPLNSNELPKRVDWREKGYVTNVKNQGGCGSCYSFSATGSLEGQYFRKSKKLVSLSEQQLIDCS--EKNSGCNGGWMNNAFQDVKIMGGIDSELDYPYKGK-KLQCNFQRSKAITSCNGYKNIDK-NENSLAIAVANEGPISVAIDASSRSFQFYKSGVYNEPNCGVNATHAVLVVGYGTDGFD----NYWIVKNSWSTAWGIKGYIWMSKDKNNQCIIASYASFP 1038
            S++++L+D W  +   + KSY   + E+ RR IWE+NL+ I++HN ++ L  +TF +G+NQF D+T+EEF+        +   +  G  ++ P +    P++VDWR++GYVT VK+Q  CGSC+SFS+TG+LEGQ FRK+ KL+S+SEQ L+DCS  + N GCNGG M+ AFQ VK   G+DSE  YPY  +  L C +     +    G+ +I + NE +L  AVA  GP+SVAIDAS +S QFY+SG+Y E  C     HAVLVVGYG  G D     YWIVKNSWS  WG KGYI+M+KDKNN C IA+ AS+P
Sbjct:   19 SIDIQLDDHWNSWKSQHGKSYHEDV-EVGRRMIWEENLRKIEQHNFEYSLGNHTFKMGMNQFGDMTNEEFRQAMNGYKQDPNRTSKGALFMEP-SFFAAPQQVDWRQRGYVTPVKDQKQCGSCWSFSSTGALEGQLFRKTGKLISMSEQNLVDCSRPQGNQGCNGGIMDQAFQYVKENKGLDSEQSYPYLARDDLPCRYDPRFNVAKITGFVDIPRGNELALMNAVAAVGPVSVAIDASHQSLQFYQSGIYYERACTSRLDHAVLVVGYGYQGADVAGNRYWIVKNSWSDKWGDKGYIYMAKDKNNHCGIATMASYP 333          
BLAST of Cathepsin L2 vs. Ensembl Xenopus
Match: ctsk (cathepsin K (pycnodysostosis) [Source:NCBI gene;Acc:448216])

HSP 1 Score: 293.123 bits (749), Expect = 8.633e-97
Identity = 154/329 (46.81%), Postives = 209/329 (63.53%), Query Frame = 1
Query:   70 TYLATSFLICFFGKCFSLNLELNDQWRLFMKIYNKSYENSLHEIIRREIWEDNLKYIQKHNLDHDLDLYTFTLGINQFADLTHEE----FKAIYLPGNFTNSKTGNTYLPPLNSNELPKRVDWREKGYVTNVKNQGGCGSCYSFSATGSLEGQYFRKSKKLVSLSEQQLIDCSEKNSGCNGGWMNNAFQDVKIMGGIDSELDYPYKGKKLQCNFQRSKAITSCNGYKNID-KNENSLAIAVANEGPISVAIDASSRSFQFYKSGVYNEPNCGVNAT-HAVLVVGYGTDGFDNYWIVKNSWSTAWGIKGYIWMSKDKNNQCIIASYASFP 1038
            + L+ +  +   G C   NL+   +W L+ K Y++ Y   L EI RR+IWE NL  I +HN +    L+T+ L +N   D+T EE       + +P    N +  NTY+P  NS  +P+ +D+R+KGYVT V NQG CGSC++FS+ G+LEGQ  +K+ KLVSLS Q L+DC   N GC GG+M NAF  V+  GGIDS+ +YPY G+   C++  +    +C GYK I   +E +L  AVAN GP+SV+IDAS  SFQFYK GVY + +C  +A  HAVLVVGYG +    +WI+KNSW   WG KGY+ +++DK N C IAS ASFP
Sbjct:   12 SLLSFALSLVKIGLCQESNLD--SKWELWKKTYHRQYNGQLDEIRRRQIWEKNLNLISQHNKEFSQGLHTYDLAMNHLGDMTSEEVVQKMMGLKVP---PNHRPNNTYIPEWNS-RIPEYIDYRKKGYVTPVHNQGICGSCWAFSSVGALEGQLMKKTGKLVSLSPQNLVDCDTDNYGCEGGYMTNAFGYVRDNGGIDSDAEYPYVGQDEGCHYNPADKAATCKGYKEIPVGSEKALKRAVANVGPVSVSIDASLPSFQFYKKGVYYDSSCNPDAVNHAVLVVGYGNEKGIKHWIIKNSWGDWWGKKGYVLLARDKKNACGIASLASFP 334          
BLAST of Cathepsin L2 vs. Ensembl Xenopus
Match: ctsk (cathepsin K (pycnodysostosis) [Source:NCBI gene;Acc:448216])

HSP 1 Score: 293.123 bits (749), Expect = 8.843e-97
Identity = 154/329 (46.81%), Postives = 209/329 (63.53%), Query Frame = 1
Query:   70 TYLATSFLICFFGKCFSLNLELNDQWRLFMKIYNKSYENSLHEIIRREIWEDNLKYIQKHNLDHDLDLYTFTLGINQFADLTHEE----FKAIYLPGNFTNSKTGNTYLPPLNSNELPKRVDWREKGYVTNVKNQGGCGSCYSFSATGSLEGQYFRKSKKLVSLSEQQLIDCSEKNSGCNGGWMNNAFQDVKIMGGIDSELDYPYKGKKLQCNFQRSKAITSCNGYKNID-KNENSLAIAVANEGPISVAIDASSRSFQFYKSGVYNEPNCGVNAT-HAVLVVGYGTDGFDNYWIVKNSWSTAWGIKGYIWMSKDKNNQCIIASYASFP 1038
            + L+ +  +   G C   NL+   +W L+ K Y++ Y   L EI RR+IWE NL  I +HN +    L+T+ L +N   D+T EE       + +P    N +  NTY+P  NS  +P+ +D+R+KGYVT V NQG CGSC++FS+ G+LEGQ  +K+ KLVSLS Q L+DC   N GC GG+M NAF  V+  GGIDS+ +YPY G+   C++  +    +C GYK I   +E +L  AVAN GP+SV+IDAS  SFQFYK GVY + +C  +A  HAVLVVGYG +    +WI+KNSW   WG KGY+ +++DK N C IAS ASFP
Sbjct:    5 SLLSFALSLVKIGLCQESNLD--SKWELWKKTYHRQYNGQLDEIRRRQIWEKNLNLISQHNKEFSQGLHTYDLAMNHLGDMTSEEVVQKMMGLKVP---PNHRPNNTYIPEWNS-RIPEYIDYRKKGYVTPVHNQGICGSCWAFSSVGALEGQLMKKTGKLVSLSPQNLVDCDTDNYGCEGGYMTNAFGYVRDNGGIDSDAEYPYVGQDEGCHYNPADKAATCKGYKEIPVGSEKALKRAVANVGPVSVSIDASLPSFQFYKKGVYYDSSCNPDAVNHAVLVVGYGNEKGIKHWIIKNSWGDWWGKKGYVLLARDKKNACGIASLASFP 327          
BLAST of Cathepsin L2 vs. Ensembl Xenopus
Match: fcrl2 (Fc receptor-like 2 [Source:Xenbase;Acc:XB-GENE-5904272])

HSP 1 Score: 290.426 bits (742), Expect = 9.919e-96
Identity = 159/315 (50.48%), Postives = 213/315 (67.62%), Query Frame = 1
Query:  133 LNDQWRLFMKIYNKSYENSLHEIIRREIWEDNLKYIQKHNLDHDLDLYTFTLGINQFADLTHEEFKAIYLPGNFTNSKT--GNTYLPPLNSNELPKRVDWREKGYVTNVKNQGGCGSCYSFSATGSLEGQYFRKSKKLVSLSEQQLIDCS--EKNSGCNGGWMNNAFQDVKIMGGIDSELDYPYKGKKLQ-CNFQRSKAITSCNGYKNIDK-NENSLAIAVANEGPISVAIDASSRSFQFYKSGVYNEPNCGV-NATHAVLVVGYGTDGFDN----YWIVKNSWSTAWGIKGYIWMSKDKNNQCIIASYASFPEV 1044
            L++ W L+   + KSY     E  RR +WE NL+ I+ HNL+H L  ++ +LG+NQF D+T+EEF+   L   + N K   G+T+L P N+ E PK VDWR+KGYVT VK+QG CGSC++FS TG+LEGQ++R + K++SLSEQ L+DCS  + N GCNGG M+ AFQ VK  GGIDSE  YPY  K  Q C++  +    +  G+ ++   +E  L  AVA+ GP+SVA+DA  +SFQFYKSG+Y EP C   +  H VLVVGYG +G D     YWIVKNSWS  WG  GYI+++KD++N C IA+ AS+P V
Sbjct:   25 LDNHWNLWKNWHKKSYAPK-EEGWRRVLWEKNLRMIEFHNLEHSLGKHSHSLGMNQFGDMTNEEFRQ--LMNGYKNQKKIRGSTFLAP-NNFESPKSVDWRKKGYVTPVKDQGQCGSCWAFSTTGALEGQHYRNTGKMISLSEQNLVDCSRAQGNQGCNGGLMDQAFQYVKDNGGIDSEDSYPYTAKDDQECHYDPNYNSANDTGFVDVTSGSEKDLMNAVASVGPVSVAVDAGHQSFQFYKSGIYYEPECSSEDLDHGVLVVGYGFEGEDEDGKKYWIVKNSWSEKWGNDGYIYIAKDRHNHCGIATAASYPLV 335          
BLAST of Cathepsin L2 vs. Ensembl Xenopus
Match: fcrl2 (Fc receptor-like 2 [Source:Xenbase;Acc:XB-GENE-5904272])

HSP 1 Score: 290.426 bits (742), Expect = 1.324e-95
Identity = 159/315 (50.48%), Postives = 213/315 (67.62%), Query Frame = 1
Query:  133 LNDQWRLFMKIYNKSYENSLHEIIRREIWEDNLKYIQKHNLDHDLDLYTFTLGINQFADLTHEEFKAIYLPGNFTNSKT--GNTYLPPLNSNELPKRVDWREKGYVTNVKNQGGCGSCYSFSATGSLEGQYFRKSKKLVSLSEQQLIDCS--EKNSGCNGGWMNNAFQDVKIMGGIDSELDYPYKGKKLQ-CNFQRSKAITSCNGYKNIDK-NENSLAIAVANEGPISVAIDASSRSFQFYKSGVYNEPNCGV-NATHAVLVVGYGTDGFDN----YWIVKNSWSTAWGIKGYIWMSKDKNNQCIIASYASFPEV 1044
            L++ W L+   + KSY     E  RR +WE NL+ I+ HNL+H L  ++ +LG+NQF D+T+EEF+   L   + N K   G+T+L P N+ E PK VDWR+KGYVT VK+QG CGSC++FS TG+LEGQ++R + K++SLSEQ L+DCS  + N GCNGG M+ AFQ VK  GGIDSE  YPY  K  Q C++  +    +  G+ ++   +E  L  AVA+ GP+SVA+DA  +SFQFYKSG+Y EP C   +  H VLVVGYG +G D     YWIVKNSWS  WG  GYI+++KD++N C IA+ AS+P V
Sbjct:   32 LDNHWNLWKNWHKKSYAPK-EEGWRRVLWEKNLRMIEFHNLEHSLGKHSHSLGMNQFGDMTNEEFRQ--LMNGYKNQKKIRGSTFLAP-NNFESPKSVDWRKKGYVTPVKDQGQCGSCWAFSTTGALEGQHYRNTGKMISLSEQNLVDCSRAQGNQGCNGGLMDQAFQYVKDNGGIDSEDSYPYTAKDDQECHYDPNYNSANDTGFVDVTSGSEKDLMNAVASVGPVSVAVDAGHQSFQFYKSGIYYEPECSSEDLDHGVLVVGYGFEGEDEDGKKYWIVKNSWSEKWGNDGYIYIAKDRHNHCGIATAASYPLV 342          
BLAST of Cathepsin L2 vs. Ensembl Xenopus
Match: ano1 (anoctamin 1, calcium activated chloride channel [Source:Xenbase;Acc:XB-GENE-5967576])

HSP 1 Score: 269.24 bits (687), Expect = 2.368e-87
Identity = 133/315 (42.22%), Postives = 196/315 (62.22%), Query Frame = 1
Query:  121 LNLELNDQWRLFMKIYNKSYENSLHEIIRREIWEDNLKYIQKHNLDHDLDLYTFTLGINQFADLTHEEFKA----IYLPGNFTNSKTGNTYLPPLNSNELPKRVDWREKGYVTNVKNQGGCGSCYSFSATGSLEGQYFRKSKKLVSLSEQQLIDCSEK--NSGCNGGWMNNAFQDVKIMGGIDSELDYPYKGKKLQCNFQRSKAITSCNGYKNI-DKNENSLAIAVANEGPISVAIDASSRSFQFYKSGVYNEPNCGVNATHAVLVVGYGTDGFDNYWIVKNSWSTAWGIKGYIWMSKDKNNQCIIASYASFPEV 1044
            +N  L++ W L+   +NK YE+ + ++ RR  WE NL  +  HNL++ + ++T+ LG+N  AD+T EE K+    + LP       T ++        ++P  +DWR+KG V++VKNQGGCGSC++FSA G+LEGQ   K+ KLVSLS Q L+DCS K  N GC GG+M  AFQ V    GIDS+  YPY     +C++  +   ++C  Y  I    E++L  A+ + GPISVAID +  SF  Y+SGVY++P C     H VL VGYG     ++W++KNSW T +G +GY+ ++++K N C +ASY  +PE+
Sbjct:   19 INPALDNHWLLWKNTHNKDYEDEIEDLQRRITWEKNLNLVNMHNLEYSMGMHTYELGMNHLADMTSEEIKSKLTGLILPPQSERQATFSSQKNSTFGGKVPDSIDWRDKGCVSDVKNQGGCGSCWAFSAVGALEGQLMLKTGKLVSLSPQNLVDCSSKYGNKGCGGGFMTQAFQYVIDNKGIDSDSYYPYHAMDEKCHYDPTGKASTCAKYTEIVPGTEDNLKQALGSIGPISVAIDGTRPSFFLYRSGVYSDPTCSHEVNHGVLAVGYGNLNGQDFWLLKNSWGTKYGDQGYVRIARNKGNLCGVASYTCYPEI 333          
BLAST of Cathepsin L2 vs. Ensembl Mouse
Match: Ctsk (cathepsin K [Source:MGI Symbol;Acc:MGI:107823])

HSP 1 Score: 286.96 bits (733), Expect = 1.520e-94
Identity = 151/316 (47.78%), Postives = 200/316 (63.29%), Query Frame = 1
Query:  115 FSLNLE--LNDQWRLFMKIYNKSYENSLHEIIRREIWEDNLKYIQKHNLDHDLDLYTFTLGINQFADLTHEEF--KAIYLPGNFTNSKTGNTYLPPLNSNELPKRVDWREKGYVTNVKNQGGCGSCYSFSATGSLEGQYFRKSKKLVSLSEQQLIDCSEKNSGCNGGWMNNAFQDVKIMGGIDSELDYPYKGKKLQCNFQRSKAITSCNGYKNID-KNENSLAIAVANEGPISVAIDASSRSFQFYKSGVYNEPNCGV-NATHAVLVVGYGTDGFDNYWIVKNSWSTAWGIKGYIWMSKDKNNQCIIASYASFPEV 1044
            F+L+ E  L+ QW L+ K + K Y + + EI RR IWE NLK I  HNL+  L ++T+ L +N   D+T EE   K   L    + S + +T   P     +P  +D+R+KGYVT VKNQG CGSC++FS+ G+LEGQ  +K+ KL++LS Q L+DC  +N GC GG+M  AFQ V+  GGIDSE  YPY G+   C +  +     C GY+ I   NE +L  AVA  GPISV+IDAS  SFQFY  GVY + NC   N  HAVLVVGYGT     +WI+KNSW  +WG KGY  ++++KNN C I + ASFP++
Sbjct:   14 FALSPEEMLDTQWELWKKTHQKQYNSKVDEISRRLIWEKNLKQISAHNLEASLGVHTYELAMNHLGDMTSEEVVQKMTGLRIPPSRSYSNDTLYTPEWEGRVPDSIDYRKKGYVTPVKNQGQCGSCWAFSSAGALEGQLKKKTGKLLALSPQNLVDCVTENYGCGGGYMTTAFQYVQQNGGIDSEDAYPYVGQDESCMYNATAKAAKCRGYREIPVGNEKALKRAVARVGPISVSIDASLASFQFYSRGVYYDENCDRDNVNHAVLVVGYGTQKGSKHWIIKNSWGESWGNKGYALLARNKNNACGITNMASFPKM 329          
BLAST of Cathepsin L2 vs. Ensembl Mouse
Match: Ctsl (cathepsin L [Source:MGI Symbol;Acc:MGI:88564])

HSP 1 Score: 281.567 bits (719), Expect = 2.701e-92
Identity = 146/308 (47.40%), Postives = 201/308 (65.26%), Query Frame = 1
Query:  142 QWRLFMKIYNKSYENSLHEIIRREIWEDNLKYIQKHNLDHDLDLYTFTLGINQFADLTHEEFKAIYLPGNFTNSKTGNTYLPPLNSNELPKRVDWREKGYVTNVKNQGGCGSCYSFSATGSLEGQYFRKSKKLVSLSEQQLIDCS--EKNSGCNGGWMNNAFQDVKIMGGIDSELDYPYKGKKLQCNFQRSKAITSCNGYKNIDKNENSLAIAVANEGPISVAIDASSRSFQFYKSGVYNEPNCGV-NATHAVLVVGYGTDGFDN----YWIVKNSWSTAWGIKGYIWMSKDKNNQCIIASYASFPEV 1044
            +W  +   + + Y  +  E  RR IWE N++ IQ HN ++    + F++ +N F D+T+EEF+ +         K G  +  PL   ++PK VDWREKG VT VKNQG CGSC++FSA+G LEGQ F K+ KL+SLSEQ L+DCS  + N GCNGG M+ AFQ +K  GG+DSE  YPY+ K   C ++   A+ +  G+ +I + E +L  AVA  GPISVA+DAS  S QFY SG+Y EPNC   N  H VL+VGYG +G D+    YW+VKNSW + WG++GYI ++KD++N C +A+ AS+P V
Sbjct:   28 EWHQWKSTHRRLYGTNEEEW-RRAIWEKNMRMIQLHNGEYSNGQHGFSMEMNAFGDMTNEEFRQVVNGYRHQKHKKGRLFQEPLML-KIPKSVDWREKGCVTPVKNQGQCGSCWAFSASGCLEGQMFLKTGKLISLSEQNLVDCSHAQGNQGCNGGLMDFAFQYIKENGGLDSEESYPYEAKDGSCKYRAEFAVANDTGFVDIPQQEKALMKAVATVGPISVAMDASHPSLQFYSSGIYYEPNCSSKNLDHGVLLVGYGYEGTDSNKNKYWLVKNSWGSEWGMEGYIKIAKDRDNHCGLATAASYPVV 333          
BLAST of Cathepsin L2 vs. Ensembl Mouse
Match: Ctsl (cathepsin L [Source:MGI Symbol;Acc:MGI:88564])

HSP 1 Score: 281.567 bits (719), Expect = 2.701e-92
Identity = 146/308 (47.40%), Postives = 201/308 (65.26%), Query Frame = 1
Query:  142 QWRLFMKIYNKSYENSLHEIIRREIWEDNLKYIQKHNLDHDLDLYTFTLGINQFADLTHEEFKAIYLPGNFTNSKTGNTYLPPLNSNELPKRVDWREKGYVTNVKNQGGCGSCYSFSATGSLEGQYFRKSKKLVSLSEQQLIDCS--EKNSGCNGGWMNNAFQDVKIMGGIDSELDYPYKGKKLQCNFQRSKAITSCNGYKNIDKNENSLAIAVANEGPISVAIDASSRSFQFYKSGVYNEPNCGV-NATHAVLVVGYGTDGFDN----YWIVKNSWSTAWGIKGYIWMSKDKNNQCIIASYASFPEV 1044
            +W  +   + + Y  +  E  RR IWE N++ IQ HN ++    + F++ +N F D+T+EEF+ +         K G  +  PL   ++PK VDWREKG VT VKNQG CGSC++FSA+G LEGQ F K+ KL+SLSEQ L+DCS  + N GCNGG M+ AFQ +K  GG+DSE  YPY+ K   C ++   A+ +  G+ +I + E +L  AVA  GPISVA+DAS  S QFY SG+Y EPNC   N  H VL+VGYG +G D+    YW+VKNSW + WG++GYI ++KD++N C +A+ AS+P V
Sbjct:   28 EWHQWKSTHRRLYGTNEEEW-RRAIWEKNMRMIQLHNGEYSNGQHGFSMEMNAFGDMTNEEFRQVVNGYRHQKHKKGRLFQEPLML-KIPKSVDWREKGCVTPVKNQGQCGSCWAFSASGCLEGQMFLKTGKLISLSEQNLVDCSHAQGNQGCNGGLMDFAFQYIKENGGLDSEESYPYEAKDGSCKYRAEFAVANDTGFVDIPQQEKALMKAVATVGPISVAMDASHPSLQFYSSGIYYEPNCSSKNLDHGVLLVGYGYEGTDSNKNKYWLVKNSWGSEWGMEGYIKIAKDRDNHCGLATAASYPVV 333          
BLAST of Cathepsin L2 vs. Ensembl Mouse
Match: Ctss (cathepsin S [Source:MGI Symbol;Acc:MGI:107341])

HSP 1 Score: 276.174 bits (705), Expect = 4.049e-90
Identity = 141/313 (45.05%), Postives = 200/313 (63.90%), Query Frame = 1
Query:  133 LNDQWRLFMKIYNKSYENSLHEIIRREIWEDNLKYIQKHNLDHDLDLYTFTLGINQFADLTHEE----FKAIYLPGNFTNSKTGNTYLPPLNSNELPKRVDWREKGYVTNVKNQGGCGSCYSFSATGSLEGQYFRKSKKLVSLSEQQLIDCSEK----NSGCNGGWMNNAFQDVKIMGGIDSELDYPYKGKKLQCNFQRSKAITSCNGYKNID-KNENSLAIAVANEGPISVAIDASSRSFQFYKSGVYNEPNCGVNATHAVLVVGYGTDGFDNYWIVKNSWSTAWGIKGYIWMSKDKNNQCIIASYASFPEV 1044
            L+  W L+ K + K Y++   E +RR IWE NLK+I  HNL++ + ++T+ +G+N   D+T+EE      A+ +P     + T  +Y    ++  LP  VDWREKG VT VK QG CG+C++FSA G+LEGQ   K+ KL+SLS Q L+DCS +    N GC GG+M  AFQ +   GGI+++  YPYK    +C++       +C+ Y  +   +E++L  AVA +GP+SV IDAS  SF FYKSGVY++P+C  N  H VLVVGYGT    +YW+VKNSW   +G +GYI M+++  N C IASY S+PE+
Sbjct:   33 LDYHWDLWKKTHEKEYKDKNEEEVRRLIWEKNLKFIMIHNLEYSMGMHTYQVGMNDMGDMTNEEILCRMGALRIPRQSPKTVTFRSY----SNRTLPDTVDWREKGCVTEVKYQGSCGACWAFSAVGALEGQLKLKTGKLISLSAQNLVDCSNEEKYGNKGCGGGYMTEAFQYIIDNGGIEADASYPYKATDEKCHYNSKNRAATCSRYIQLPFGDEDALKEAVATKGPVSVGIDASHSSFFFYKSGVYDDPSCTGNVNHGVLVVGYGTLDGKDYWLVKNSWGLNFGDQGYIRMARNNKNHCGIASYCSYPEI 341          
BLAST of Cathepsin L2 vs. Ensembl Mouse
Match: Ctss (cathepsin S [Source:MGI Symbol;Acc:MGI:107341])

HSP 1 Score: 275.789 bits (704), Expect = 4.666e-90
Identity = 141/313 (45.05%), Postives = 200/313 (63.90%), Query Frame = 1
Query:  133 LNDQWRLFMKIYNKSYENSLHEIIRREIWEDNLKYIQKHNLDHDLDLYTFTLGINQFADLTHEE----FKAIYLPGNFTNSKTGNTYLPPLNSNELPKRVDWREKGYVTNVKNQGGCGSCYSFSATGSLEGQYFRKSKKLVSLSEQQLIDCSEK----NSGCNGGWMNNAFQDVKIMGGIDSELDYPYKGKKLQCNFQRSKAITSCNGYKNID-KNENSLAIAVANEGPISVAIDASSRSFQFYKSGVYNEPNCGVNATHAVLVVGYGTDGFDNYWIVKNSWSTAWGIKGYIWMSKDKNNQCIIASYASFPEV 1044
            L+  W L+ K + K Y++   E +RR IWE NLK+I  HNL++ + ++T+ +G+N   D+T+EE      A+ +P     + T  +Y    ++  LP  VDWREKG VT VK QG CG+C++FSA G+LEGQ   K+ KL+SLS Q L+DCS +    N GC GG+M  AFQ +   GGI+++  YPYK    +C++       +C+ Y  +   +E++L  AVA +GP+SV IDAS  SF FYKSGVY++P+C  N  H VLVVGYGT    +YW+VKNSW   +G +GYI M+++  N C IASY S+PE+
Sbjct:   32 LDYHWDLWKKTHEKEYKDKNEEEVRRLIWEKNLKFIMIHNLEYSMGMHTYQVGMNDMGDMTNEEILCRMGALRIPRQSPKTVTFRSY----SNRTLPDTVDWREKGCVTEVKYQGSCGACWAFSAVGALEGQLKLKTGKLISLSAQNLVDCSNEEKYGNKGCGGGYMTEAFQYIIDNGGIEADASYPYKATDEKCHYNSKNRAATCSRYIQLPFGDEDALKEAVATKGPVSVGIDASHSSFFFYKSGVYDDPSCTGNVNHGVLVVGYGTLDGKDYWLVKNSWGLNFGDQGYIRMARNNKNHCGIASYCSYPEI 340          
BLAST of Cathepsin L2 vs. UniProt/SwissProt
Match: sp|Q9GL24|CATL1_CANLF (Cathepsin L1 OS=Canis lupus familiaris OX=9615 GN=CTSL PE=2 SV=1)

HSP 1 Score: 297.36 bits (760), Expect = 1.156e-97
Identity = 156/311 (50.16%), Postives = 208/311 (66.88%), Query Frame = 1
Query:  133 LNDQWRLFMKIYNKSYENSLHEIIRREIWEDNLKYIQKHNLDHDLDLYTFTLGINQFADLTHEEFKAIYLPGNFTNSKTGNTYLPPLNSNELPKRVDWREKGYVTNVKNQGGCGSCYSFSATGSLEGQYFRKSKKLVSLSEQQLIDCS--EKNSGCNGGWMNNAFQDVKIMGGIDSELDYPYKGKKLQ-CNFQRSKAITSCNGYKNIDKNENSLAIAVANEGPISVAIDASSRSFQFYKSGVYNEPNCGV-NATHAVLVVGYGTDGFDN---YWIVKNSWSTAWGIKGYIWMSKDKNNQCIIASYASFPEV 1044
            LN QW  +   + + Y  +  E  RR +WE N+K I+ HN ++    + FT+ +N F D+T+EEF+ +         K G  +  PL + E+PK VDWREKGYVT VKNQG CGSC++FSATG+LEGQ FRK+ KLVSLSEQ L+DCS  + N GCNGG M+NAF+ VK  GG+DSE  YPY G+  + CN++   +  +  G+ ++ + E +L  AVA  GPISVAIDA  +SFQFYKSG+Y +P+C   +  H VLVVGYG +G D+   +WIVKNSW   WG  GY+ M+KD+NN C IA+ AS+P V
Sbjct:   25 LNAQWYQWKATHRRLYGMN-EEGWRRAVWEKNMKMIELHNREYSQGKHGFTMAMNAFGDMTNEEFRQVMNGFQNQKHKKGKMFQEPLFA-EIPKSVDWREKGYVTPVKNQGQCGSCWAFSATGALEGQMFRKTGKLVSLSEQNLVDCSRAQGNEGCNGGLMDNAFRYVKDNGGLDSEESYPYLGRDTETCNYKPECSAANDTGFVDLPQREKALMKAVATLGPISVAIDAGHQSFQFYKSGIYFDPDCSSKDLDHGVLVVGYGFEGTDSNNKFWIVKNSWGPEWGWNGYVKMAKDQNNHCGIATAASYPTV 333          
BLAST of Cathepsin L2 vs. UniProt/SwissProt
Match: sp|Q9GKL8|CATL1_CHLAE (Cathepsin L1 OS=Chlorocebus aethiops OX=9534 GN=CTSL PE=1 SV=1)

HSP 1 Score: 295.049 bits (754), Expect = 9.287e-97
Identity = 153/332 (46.08%), Postives = 206/332 (62.05%), Query Frame = 1
Query:   70 TYLATSFLICFFGKCFSLNLELNDQWRLFMKIYNKSYENSLHEIIRREIWEDNLKYIQKHNLDHDLDLYTFTLGINQFADLTHEEFKAIYLPGNFTNSKTGNTYLPPLNSNELPKRVDWREKGYVTNVKNQGGCGSCYSFSATGSLEGQYFRKSKKLVSLSEQQLIDCS--EKNSGCNGGWMNNAFQDVKIMGGIDSELDYPYKGKKLQCNFQRSKAITSCNGYKNIDKNENSLAIAVANEGPISVAIDASSRSFQFYKSGVYNEPNCGV-NATHAVLVVGYGTDGFDN----YWIVKNSWSTAWGIKGYIWMSKDKNNQCIIASYASFPEV 1044
            T++  +  +       + N  L  QW  +  ++N+ Y  +  E  RR +WE N+K I+ HN ++    ++FT+ +N F D+T EEF+ +         + G  +  PL   E P+ VDWREKGYVT VKNQG CGSC++FSATG+LEGQ FRK+ KLVSLSEQ L+DCS  + N GCNGG M+ AFQ V   GG+DSE  YPY+  +  C +    ++ +  G+ +I K E +L  AVA  GPISVAIDA   SF FYK G+Y EP+C   +  H VLVVGYG +  ++    YW+VKNSW   WG+ GYI M+KD+ N C IAS AS+P V
Sbjct:    4 TFILAALCLGIASATLTFNHSLEAQWTKWKAMHNRLYGMN-EEGWRRAVWEKNMKMIELHNQEYSQGKHSFTMAMNTFGDMTSEEFRQVMNGFQNRKPRKGKVFQEPL-FYEAPRSVDWREKGYVTPVKNQGQCGSCWAFSATGALEGQMFRKTGKLVSLSEQNLVDCSGPQGNEGCNGGLMDYAFQYVADNGGLDSEESYPYEATEESCKYNPEYSVANDTGFVDIPKQEKALMKAVATVGPISVAIDAGHESFMFYKEGIYFEPDCSSEDMDHGVLVVGYGFESTESDNSKYWLVKNSWGEEWGMGGYIKMAKDRRNHCGIASAASYPTV 333          
BLAST of Cathepsin L2 vs. UniProt/SwissProt
Match: sp|P07711|CATL1_HUMAN (Cathepsin L1 OS=Homo sapiens OX=9606 GN=CTSL PE=1 SV=2)

HSP 1 Score: 291.197 bits (744), Expect = 3.263e-95
Identity = 150/332 (45.18%), Postives = 207/332 (62.35%), Query Frame = 1
Query:   70 TYLATSFLICFFGKCFSLNLELNDQWRLFMKIYNKSYENSLHEIIRREIWEDNLKYIQKHNLDHDLDLYTFTLGINQFADLTHEEFKAIYLPGNFTNSKTGNTYLPPLNSNELPKRVDWREKGYVTNVKNQGGCGSCYSFSATGSLEGQYFRKSKKLVSLSEQQLIDCS--EKNSGCNGGWMNNAFQDVKIMGGIDSELDYPYKGKKLQCNFQRSKAITSCNGYKNIDKNENSLAIAVANEGPISVAIDASSRSFQFYKSGVYNEPNCGV-NATHAVLVVGYGTDGFDN----YWIVKNSWSTAWGIKGYIWMSKDKNNQCIIASYASFPEV 1044
            T +  +F +       + +  L  QW  +  ++N+ Y  +  E  RR +WE N+K I+ HN ++    ++FT+ +N F D+T EEF+ +         + G  +  PL   E P+ VDWREKGYVT VKNQG CGSC++FSATG+LEGQ FRK+ +L+SLSEQ L+DCS  + N GCNGG M+ AFQ V+  GG+DSE  YPY+  +  C +    ++ +  G+ +I K E +L  AVA  GPISVAIDA   SF FYK G+Y EP+C   +  H VLVVGYG +  ++    YW+VKNSW   WG+ GY+ M+KD+ N C IAS AS+P V
Sbjct:    4 TLILAAFCLGIASATLTFDHSLEAQWTKWKAMHNRLYGMN-EEGWRRAVWEKNMKMIELHNQEYREGKHSFTMAMNAFGDMTSEEFRQVMNGFQNRKPRKGKVFQEPL-FYEAPRSVDWREKGYVTPVKNQGQCGSCWAFSATGALEGQMFRKTGRLISLSEQNLVDCSGPQGNEGCNGGLMDYAFQYVQDNGGLDSEESYPYEATEESCKYNPKYSVANDTGFVDIPKQEKALMKAVATVGPISVAIDAGHESFLFYKEGIYFEPDCSSEDMDHGVLVVGYGFESTESDNNKYWLVKNSWGEEWGMGGYVKMAKDRRNHCGIASAASYPTV 333          
BLAST of Cathepsin L2 vs. UniProt/SwissProt
Match: sp|P43235|CATK_HUMAN (Cathepsin K OS=Homo sapiens OX=9606 GN=CTSK PE=1 SV=1)

HSP 1 Score: 290.812 bits (743), Expect = 3.603e-95
Identity = 150/308 (48.70%), Postives = 198/308 (64.29%), Query Frame = 1
Query:  133 LNDQWRLFMKIYNKSYENSLHEIIRREIWEDNLKYIQKHNLDHDLDLYTFTLGINQFADLTHEEF--KAIYLPGNFTNSKTGNTYLPPLNSNELPKRVDWREKGYVTNVKNQGGCGSCYSFSATGSLEGQYFRKSKKLVSLSEQQLIDCSEKNSGCNGGWMNNAFQDVKIMGGIDSELDYPYKGKKLQCNFQRSKAITSCNGYKNI-DKNENSLAIAVANEGPISVAIDASSRSFQFYKSGVYNEPNCGV-NATHAVLVVGYGTDGFDNYWIVKNSWSTAWGIKGYIWMSKDKNNQCIIASYASFPEV 1044
            L+  W L+ K + K Y N + EI RR IWE NLKYI  HNL+  L ++T+ L +N   D+T EE   K   L    ++S++ +T   P      P  VD+R+KGYVT VKNQG CGSC++FS+ G+LEGQ  +K+ KL++LS Q L+DC  +N GC GG+M NAFQ V+   GIDSE  YPY G++  C +  +     C GY+ I + NE +L  AVA  GP+SVAIDAS  SFQFY  GVY + +C   N  HAVL VGYG    + +WI+KNSW   WG KGYI M+++KNN C IA+ ASFP++
Sbjct:   22 LDTHWELWKKTHRKQYNNKVDEISRRLIWEKNLKYISIHNLEASLGVHTYELAMNHLGDMTSEEVVQKMTGLKVPLSHSRSNDTLYIPEWEGRAPDSVDYRKKGYVTPVKNQGQCGSCWAFSSVGALEGQLKKKTGKLLNLSPQNLVDCVSENDGCGGGYMTNAFQYVQKNRGIDSEDAYPYVGQEESCMYNPTGKAAKCRGYREIPEGNEKALKRAVARVGPVSVAIDASLTSFQFYSKGVYYDESCNSDNLNHAVLAVGYGIQKGNKHWIIKNSWGENWGNKGYILMARNKNNACGIANLASFPKM 329          
BLAST of Cathepsin L2 vs. UniProt/SwissProt
Match: sp|P43236|CATK_RABIT (Cathepsin K OS=Oryctolagus cuniculus OX=9986 GN=CTSK PE=1 SV=1)

HSP 1 Score: 290.426 bits (742), Expect = 4.428e-95
Identity = 153/316 (48.42%), Postives = 203/316 (64.24%), Query Frame = 1
Query:  115 FSLNLE--LNDQWRLFMKIYNKSYENSLHEIIRREIWEDNLKYIQKHNLDHDLDLYTFTLGINQFADLTHEEF--KAIYLPGNFTNSKTGNTYLPPLNSNELPKRVDWREKGYVTNVKNQGGCGSCYSFSATGSLEGQYFRKSKKLVSLSEQQLIDCSEKNSGCNGGWMNNAFQDVKIMGGIDSELDYPYKGKKLQCNFQRSKAITSCNGYKNI-DKNENSLAIAVANEGPISVAIDASSRSFQFYKSGVYNEPNCGV-NATHAVLVVGYGTDGFDNYWIVKNSWSTAWGIKGYIWMSKDKNNQCIIASYASFPEV 1044
            F+L+ E  L+ QW L+ K Y+K Y + + EI RR IWE NLK+I  HNL+  L ++T+ L +N   D+T EE   K   L    + S + +T   P      P  +D+R+KGYVT VKNQG CGSC++FS+ G+LEGQ  +K+ KL++LS Q L+DC  +N GC GG+M NAFQ V+   GIDSE  YPY G+   C +  +     C GY+ I + NE +L  AVA  GP+SVAIDAS  SFQFY  GVY + NC   N  HAVL VGYG    + +WI+KNSW  +WG KGYI M+++KNN C IA+ ASFP++
Sbjct:   14 FALHPEEILDTQWELWKKTYSKQYNSKVDEISRRLIWEKNLKHISIHNLEASLGVHTYELAMNHLGDMTSEEVVQKMTGLKVPPSRSHSNDTLYIPDWEGRTPDSIDYRKKGYVTPVKNQGQCGSCWAFSSVGALEGQLKKKTGKLLNLSPQNLVDCVSENYGCGGGYMTNAFQYVQRNRGIDSEDAYPYVGQDESCMYNPTGKAAKCRGYREIPEGNEKALKRAVARVGPVSVAIDASLTSFQFYSKGVYYDENCSSDNVNHAVLAVGYGIQKGNKHWIIKNSWGESWGNKGYILMARNKNNACGIANLASFPKM 329          
BLAST of Cathepsin L2 vs. TrEMBL
Match: A0A2U8U447 (Cathepsin L2 OS=Dugesia japonica OX=6161 PE=2 SV=1)

HSP 1 Score: 349.747 bits (896), Expect = 7.486e-116
Identity = 176/319 (55.17%), Postives = 233/319 (73.04%), Query Frame = 1
Query:  115 FSLNLELNDQWRLFMKIYNKSYENSLHEIIRREIWEDNLKYIQKHNLDHDLDLYTFTLGINQFADLTHEEFKAIYLP-----GNFTNSKTGNTYLPPLNSNELPKRVDWREKGYVTNVKNQGGCGSCYSFSATGSLEGQYFRKSKKLVSLSEQQLIDCSEK--NSGCNGGWMNNAFQDVKIMGGIDSELDYPYKGKKLQCNFQRSKAITSCNGYKNIDK-NENSLAIAVANEGPISVAIDASSRSFQFYKSGVYNEPNCGV-NATHAVLVVGYGTDGFDNYWIVKNSWSTAWGIKGYIWMSKDKNNQCIIASYASFPEV 1044
            F++N ELND+W ++   ++K YE +L+EI RR IWE+NLK+IQ+HN+++DL  +T+ LG+N+FAD+THEEFKA YL       NFT+S+    ++ P N  +LP R+DWR KGYVT VKNQG CGSC++FS TGSLEGQ+FRKS KLVS SEQQL+DCS    N GCNGG M+NAF  ++   GI++E+ YPY      C + ++K + +C G+ +I   NE  L  AVA +GPISVAIDAS+ SFQFY+ G+YNEP+C   +  H VL +GYG++  +NYWIVKNSW  +WG+ GYI MSKDK NQC IA+ AS+P V
Sbjct:   21 FTINSELNDEWEVYKMKFSKKYE-TLNEISRRIIWENNLKFIQQHNVEYDLGKHTYYLGLNEFADMTHEEFKAKYLGLKPINRNFTSSR----FIIPENIGDLPTRIDWRTKGYVTPVKNQGQCGSCWAFSTTGSLEGQHFRKSGKLVSFSEQQLVDCSRSFDNLGCNGGLMDNAFSYIQKF-GIENEISYPYVANDGVCAYDKTKIVGTCTGFVDIKTGNETDLMAAVATQGPISVAIDASNDSFQFYRGGIYNEPHCSSKDLDHGVLAIGYGSENNENYWIVKNSWDISWGMSGYIRMSKDKMNQCGIATMASYPLV 333          
BLAST of Cathepsin L2 vs. TrEMBL
Match: A0A267H1I6 (Uncharacterized protein OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig013052g1 PE=3 SV=1)

HSP 1 Score: 334.339 bits (856), Expect = 7.831e-110
Identity = 169/312 (54.17%), Postives = 215/312 (68.91%), Query Frame = 1
Query:  121 LNLELNDQWRLFMKIYNKSYENSLHEIIRREIWEDNLKYIQKHNLDHDLDLYTFTLGINQFADLTHEEFKAIYLPGNFTNSKTGNTYLPPLNSNELPKRVDWREKGYVTNVKNQGGCGSCYSFSATGSLEGQYFRKSKKLVSLSEQQLIDCSEK--NSGCNGGWMNNAFQDVKIMGGIDSELDYPYKGKKLQCNFQRSKAITSCNGYKNID-KNENSLAIAVANEGPISVAIDASSRSFQFYKSGVYNEPNCG-VNATHAVLVVGYGTDGFDNYWIVKNSWSTAWGIKGYIWMSKDKNNQCIIASYASFPEV 1044
              LELN++W  +   + K YE    E++RR IWE NL++IQKHNL++D  ++++TLG+NQF DLT  EFKA YL         G+ +LP  N   LP  VDWR KGYVT VK+Q  CGSC++FS TGSLEGQ+F+K+  LVSLSEQ L+DCS K  N GCNGG M+N F+ +K   GID+E  YPYK +  +C+F+ S    + +G+ +I  KNE++L  AVA  GPISVAIDA   SFQ YKSGVY+E  C      H VL VGYGT+G   YW+VKNSW T+WG+KGYI MS++K NQC IAS AS+P V
Sbjct:   21 FTLELNEEWEAYKSTHGKVYEAD-EELMRRLIWEQNLQHIQKHNLEYDRGVHSYTLGMNQFGDLTFTEFKAKYLSPMPAAEPEGSVFLPASNVGSLPDEVDWRTKGYVTGVKDQKQCGSCWAFSTTGSLEGQHFKKTGNLVSLSEQNLVDCSGKFGNMGCNGGLMDNGFKYIKANKGIDTEACYPYKARDEKCSFKSSCVGATVSGFVDIPAKNESALQQAVATIGPISVAIDAGHSSFQLYKSGVYSERLCSETQLDHGVLAVGYGTEGGKAYWLVKNSWGTSWGMKGYIMMSRNKKNQCGIASAASYPLV 331          
BLAST of Cathepsin L2 vs. TrEMBL
Match: A0A1I8GVB7 (Uncharacterized protein OS=Macrostomum lignano OX=282301 PE=3 SV=1)

HSP 1 Score: 334.339 bits (856), Expect = 9.220e-110
Identity = 169/312 (54.17%), Postives = 215/312 (68.91%), Query Frame = 1
Query:  121 LNLELNDQWRLFMKIYNKSYENSLHEIIRREIWEDNLKYIQKHNLDHDLDLYTFTLGINQFADLTHEEFKAIYLPGNFTNSKTGNTYLPPLNSNELPKRVDWREKGYVTNVKNQGGCGSCYSFSATGSLEGQYFRKSKKLVSLSEQQLIDCSEK--NSGCNGGWMNNAFQDVKIMGGIDSELDYPYKGKKLQCNFQRSKAITSCNGYKNID-KNENSLAIAVANEGPISVAIDASSRSFQFYKSGVYNEPNCG-VNATHAVLVVGYGTDGFDNYWIVKNSWSTAWGIKGYIWMSKDKNNQCIIASYASFPEV 1044
              LELN++W  +   + K YE    E++RR IWE NL++IQKHNL++D  ++++TLG+NQF DLT  EFKA YL         G+ +LP  N   LP  VDWR KGYVT VK+Q  CGSC++FS TGSLEGQ+F+K+  LVSLSEQ L+DCS K  N GCNGG M+N F+ +K   GID+E  YPYK +  +C+F+ S    + +G+ +I  KNE++L  AVA  GPISVAIDA   SFQ YKSGVY+E  C      H VL VGYGT+G   YW+VKNSW T+WG+KGYI MS++K NQC IAS AS+P V
Sbjct:   21 FTLELNEEWEAYKSTHGKVYEAD-EELMRRLIWEQNLQHIQKHNLEYDRGVHSYTLGMNQFGDLTFTEFKAKYLSPMPAAEPEGSVFLPASNVGSLPDEVDWRTKGYVTGVKDQKQCGSCWAFSTTGSLEGQHFKKTGNLVSLSEQNLVDCSGKFGNMGCNGGLMDNGFKYIKANKGIDTEACYPYKARDEKCSFKSSCVGATVSGFVDIPAKNESALQHAVATIGPISVAIDAGHSSFQLYKSGVYSERLCSETQLDHGVLAVGYGTEGGKAYWLVKNSWGTSWGMKGYIMMSRNKKNQCGIASAASYPLV 331          
BLAST of Cathepsin L2 vs. TrEMBL
Match: A0A147BAD2 (Cathepsin l (Fragment) OS=Carios mimon OX=360319 PE=3 SV=1)

HSP 1 Score: 327.791 bits (839), Expect = 4.135e-107
Identity = 163/336 (48.51%), Postives = 226/336 (67.26%), Query Frame = 1
Query:   52 LSLQMNTYLATSFLICFFGKCFSLNLELNDQWRLFMKIYNKSYENSLHEIIRREIWEDNLKYIQKHNLDHDLDLYTFTLGINQFADLTHEEFKAIYLPGNFTNSKTGNTYLP---PLNSNELPKRVDWREKGYVTNVKNQGGCGSCYSFSATGSLEGQYFRKSKKLVSLSEQQLIDCSEKNSGCNGGWMNNAFQDVKIMGGIDSELDYPYKGKKLQCNFQRSKAITSCNGYKNIDK-NENSLAIAVANEGPISVAIDASSRSFQFYKSGVYNEPNC-GVNATHAVLVVGYGTDGFDNYWIVKNSWSTAWGIKGYIWMSKDKNNQCIIASYASFPEV 1044
            +++    +L  + L C   +      +L+D W ++ +++ K Y     E  RR +WE+NL +IQKHNL++DL L+T T+ +N FADLT EE++ IYL   +  ++T    L     ++  +LP  VDWR++GYVT VK+QG CGSC++FSATGSLEGQ+FRK+ KLVSLSEQ L+DC E + GCNGG M++AF  +   GG+D+E  YPY      C++       +  GY +I+  +E++L  AVA  GP+SVAIDAS  SF+FY+SGVYNEPNC  VN  H VLVVGYGT+   +YWIVKNSW  +WG  GYI MS++++NQC IA+ AS+P V
Sbjct:    1 VTMAFKAFLLLAVLTCSLARTVPRQ-DLDDHWEIYKQVHRKKY-GPQEEQRRRLVWEENLDFIQKHNLEYDLGLHTHTVAVNSFADLTSEEYRIIYL--GYRQNRTRRPALAVHTEVSLYDLPDEVDWRDEGYVTPVKDQGQCGSCWAFSATGSLEGQHFRKTGKLVSLSEQNLVDCDETSLGCNGGSMDSAFDYIHANGGLDTEASYPYTATTGTCHYDPDHVGATDKGYHDIESGSEDALQGAVAAVGPVSVAIDASQDSFRFYQSGVYNEPNCDSVNLDHGVLVVGYGTESDGDYWIVKNSWGESWGNDGYILMSRNRDNQCGIATQASYPVV 332          
BLAST of Cathepsin L2 vs. TrEMBL
Match: A0A1Z5KUE4 (Uncharacterized protein (Fragment) OS=Ornithodoros moubata OX=6938 PE=3 SV=1)

HSP 1 Score: 327.02 bits (837), Expect = 7.847e-107
Identity = 165/334 (49.40%), Postives = 227/334 (67.96%), Query Frame = 1
Query:   58 LQMNTYLATSFLICFFGKCFSLNLELNDQWRLFMKIYNKSYENSLHEIIRREIWEDNLKYIQKHNLDHDLDLYTFTLGINQFADLTHEEFKAIYLPGNFTNSKTGNTYLP---PLNSNELPKRVDWREKGYVTNVKNQGGCGSCYSFSATGSLEGQYFRKSKKLVSLSEQQLIDCSEKNSGCNGGWMNNAFQDVKIMGGIDSELDYPYKGKKLQCNFQRSKAITSCNGYKNIDK-NENSLAIAVANEGPISVAIDASSRSFQFYKSGVYNEPNCGVNA-THAVLVVGYGTDGFDNYWIVKNSWSTAWGIKGYIWMSKDKNNQCIIASYASFPEV 1044
            + +   + ++ + C   +      +LN  W ++ +++ K Y     E  RR IWEDNL +IQKHNL++DL L+T+ +G+N FADLT +E++  +L   + +++T    L     ++  +LP+ VDWRE+GYVT VKNQG CGSC++FSATGSLEGQ+FRK+ KLVSLSEQ L+DC + + GCNGG M++AFQ V+  GGID+E  YPY      C F  S    +  GY +++  +E+ L  AVA  GP+SVAIDAS  SFQFY+SGVYNEP+C   +  H VLVVGYGT   ++YWIVKNSW  AWG +GYI MS++++NQC IAS AS+P V
Sbjct:    1 MSLRLLVVSAIVACALARTVP-RPQLNAHWEVYKEVHQKKY-GPGEENRRRLIWEDNLDFIQKHNLEYDLGLHTYRVGVNSFADLTSKEYRETFL--GYRHNRTRKVPLATHQAISLYDLPEHVDWREEGYVTPVKNQGQCGSCWAFSATGSLEGQHFRKTGKLVSLSEQNLVDCDQTSDGCNGGSMDSAFQYVQSNGGIDTESSYPYVAHDEACEFNPSTVGATDKGYHDVESGSEDDLQSAVATVGPVSVAIDASQNSFQFYQSGVYNEPDCSSKSLDHGVLVVGYGTLNDEDYWIVKNSWGEAWGDEGYILMSRNRDNQCGIASDASYPLV 330          
BLAST of Cathepsin L2 vs. Ensembl Cavefish
Match: si:dkey-26g8.5 (cathepsin L1-like [Source:NCBI gene;Acc:103028700])

HSP 1 Score: 303.523 bits (776), Expect = 6.342e-101
Identity = 170/338 (50.30%), Postives = 218/338 (64.50%), Query Frame = 1
Query:   58 LQMNTYLATSFLICFFGKCFSLNLELNDQWRLFMKIYNKSYENSLHEIIRREIWEDNLKYIQKHNLDHDLDLYTFTLGINQFADLTHEEFKAIY--LPGNFTNSKTGNTYLPPLNSNELPKRVDWREKGYVTNVKNQGGCGSCYSFSATGSLEGQYFRKSKKLVSLSEQQLIDCS--EKNSGCNGGWMNNAFQDVKIMGGIDSELDYPYKGKKLQ-CNFQRSKAITSCNGYKNIDK-NENSLAIAVANEGPISVAIDASSRSFQFYKSGVYNEPNCGVNA-THAVLVVGYGTDGFDN----YWIVKNSWSTAWGIKGYIWMSKDKNNQCIIASYASFP 1038
            L + + LA  F   F     SL+ +L+D W+L+   ++KSY     E  RR +WE NLK ++ HNL+H +  +T+ LG+NQFAD+T+EEF+        N      G+ +L P +  E+PK+VDWREKGYVT VK+Q  CGSC++FS+TG+LEGQ+FRK+ KLVSLSEQ L+DCS  E N GCNGG M  AFQ VK  GGIDSE  YPY  K  Q C +  +    +  G+ +I    E++L  AVA  GP+SVAIDA   SFQFY+SG+Y E  C      H VLVVGYG +G D     YWIVKNSWS  WG  GYI+M+KD+ N C IAS AS+P
Sbjct:    3 LTLASLLALCFCTGFTAP--SLDRQLDDHWKLWKSWHSKSYHEK-EEGWRRLVWEKNLKKVELHNLEHSMGKHTYRLGMNQFADMTNEEFRQAMNGYRSNPNKKSKGSLFLEP-SFLEVPKQVDWREKGYVTPVKDQARCGSCWAFSSTGALEGQHFRKTGKLVSLSEQNLVDCSRPEGNQGCNGGIMEQAFQYVKDNGGIDSEESYPYTAKDDQPCRYDPNFNSANDTGFVDIPSGEEHALMKAVAAVGPVSVAIDAGHESFQFYQSGIYYEKACSSEELDHGVLVVGYGFEGADEDGKKYWIVKNSWSEKWGQNGYIYMAKDRKNHCGIASAASYP 336          
BLAST of Cathepsin L2 vs. Ensembl Cavefish
Match: ctss2.1 (cathepsin S [Source:NCBI gene;Acc:103044830])

HSP 1 Score: 294.278 bits (752), Expect = 1.856e-97
Identity = 150/321 (46.73%), Postives = 198/321 (61.68%), Query Frame = 1
Query:   88 FLICFFGKCFSL-NLELNDQWRLFMKIYNKSYENSLHEIIRREIWEDNLKYIQKHNLDHDLDLYTFTLGINQFADLTHEEFKAIYLPGNFTNSKTGNTYLPPLNSNELPKRVDWREKGYVTNVKNQGGCGSCYSFSATGSLEGQYFRKSKKLVSLSEQQLIDCSEK--NSGCNGGWMNNAFQDVKIMGGIDSELDYPYKGKKLQCNFQRSKAITSCNGYKNI-DKNENSLAIAVANEGPISVAIDASSRSFQFYKSGVYNEPNCGVNATHAVLVVGYGTDGFDNYWIVKNSWSTAWGIKGYIWMSKDKNNQCIIASYASFP 1038
            FL    G   +L +  L+  W+L+ K + KSY   + E+ RREIWE NL+ I  HNL+  +D++T+ L +N   DLT EE   +       +     +        ++P  VDWREKGYVTNVK QG CGSC++FSA G+LEGQ  R + +LVSLS Q L+DCS K  N GC+GG+M+ AFQ V   GGIDS+  YPY G   QC +  S    +C  Y  + + NE +L  AVA  GP+SVAIDA+   F  Y+SGVY +P+C  N  H VLVVGYGT   ++YW+VKNSW T +G  GYI M+++K N C IASY  +P
Sbjct:    6 FLTLLCGAAVALSDPNLDQHWQLWKKKHYKSYSTEVEEMGRREIWERNLQLISLHNLEASMDIHTYDLAMNHMGDLTREEILDMMAGTRVPSHLKKRSSFVSFAGVQVPDSVDWREKGYVTNVKQQGACGSCWAFSAAGALEGQLMRTTGQLVSLSPQNLVDCSSKYGNKGCHGGFMSRAFQYVIDNGGIDSDASYPYNGMDGQCKYNPSDRAANCTSYSFLPEGNEEALKTAVATIGPVSVAIDATRPQFILYRSGVYYDPSCTKNVNHGVLVVGYGTLNGEDYWLVKNSWGTGFGDGGYIRMARNKGNMCGIASYCCYP 326          
BLAST of Cathepsin L2 vs. Ensembl Cavefish
Match: ctsla (cathepsin L1-like [Source:NCBI gene;Acc:103043056])

HSP 1 Score: 288.115 bits (736), Expect = 6.007e-95
Identity = 163/332 (49.10%), Postives = 208/332 (62.65%), Query Frame = 1
Query:   94 ICFFGKCFS-------LNLELNDQWRLFMKIYNKSYENSLHEIIRREIWEDNLKYIQKHNLDHDLDLYTFTLGINQFADLTHEEFKAIYLPGNFTNSKTGNTYLPPLNSNELPKRVDWREKGYVTNVKNQGGCGSCYSFSATGSLEGQYFRKSKKLVSLSEQQLIDCS--EKNSGCNGGWMNNAFQDVKIMGGIDSELDYPYKGKKLQ-CNFQ-RSKAITSCNGYKNIDK-NENSLAIAVANEGPISVAIDASSRSFQFYKSGVYNEPNCGVNA-THAVLVVGYGTDGFD----NYWIVKNSWSTAWGIKGYIWMSKDKNNQCIIASYASFP 1038
            + FF  CFS       L+ +L++ W  F KI +K Y+    E  RR IWE+N K I  HN+++ L +  + LG+N+F D+T+EEFK I       N K   +     +    P +VDWREKGYVT VK+QG CGSC++FS TG+LEGQ F+K+ KLVSLSEQ L+DCS  E N GCNGG MN AFQ ++  GG++SE  YPY G   Q CN+     +    NG+ +I    EN L   VA  GP+SVAIDA   SFQFY+SG+YNE +C  +   H VLVVGYG  G D     YWIVKNSW   WG  GYI+M+KD+ NQC IA+ AS+P
Sbjct:    3 LAFFAVCFSTVFAASGLDHDLDNNWEQFKKINSKKYQEK-EEGWRRGIWENNFKKIVMHNINNSLGIVPYRLGMNRFGDMTNEEFKQIRNGFKQINEKVRRSVFIVPDFPAAPAQVDWREKGYVTPVKDQGDCGSCWAFSTTGALEGQQFKKTGKLVSLSEQNLVDCSRPEGNEGCNGGLMNLAFQYIQNRGGLNSEGSYPYLGTDDQPCNYNPNDNSAVINNGFVDISSGTENDLMKTVAAIGPVSVAIDAGHESFQFYQSGIYNEKDCSSDELNHGVLVVGYGFQGEDVEGKRYWIVKNSWGKDWGDDGYIYMAKDQQNQCGIATAASYP 333          
BLAST of Cathepsin L2 vs. Ensembl Cavefish
Match: ENSAMXT00000001970.2 (cathepsin L1-like [Source:NCBI gene;Acc:103022163])

HSP 1 Score: 287.345 bits (734), Expect = 1.080e-94
Identity = 155/316 (49.05%), Postives = 209/316 (66.14%), Query Frame = 1
Query:  124 NLELNDQWRLFMKIYNKSYENSLHEIIRREIWEDNLKYIQKHNLDHDLDLYTFTLGINQFADLTHEEFKAIY----LPGNFTNSKTGNTYLPPLNSNELPKRVDWREKGYVTNVKNQGGCGSCYSFSATGSLEGQYFRKSKKLVSLSEQQLIDCSEK--NSGCNGGWMNNAFQDVKIMGGIDSELDYPYKGKKLQCNFQRSKAITSCNGYKNIDK-NENSLAIAVANEGPISVAIDASSRSFQFYKSGVYNEPNC-GVNATHAVLVVGYGTDGFDN-YWIVKNSWSTAWGIKGYIWMSKDKNNQCIIASYASFPEV 1044
            +LE N  W+L    + KSY +   E  R+ IW  N K + KHN+  D  L ++ LG+N FAD+ ++EF+A++       + T+S   +T+L       LP+RVDWR KGYVT VKNQG CGSC++FSATG+LEGQ FRK+ KL+SLSEQQL+DCS+   N GCNGGW + +F  +K   G++++  YPYK +K  C F   + I +C+G+K++ K +EN+L  AVA+ GPISV ID S  +FQ YKSGVY+EP C      HAVL+VGY  D     YW+VKNSW   WG  GYI MS++K NQC IA+ A++P V
Sbjct:   23 DLEFN-SWKL---QHGKSYGSEEEESQRKMIWLTNRKLVLKHNMLADQGLKSYRLGMNIFADMKNQEFQAMFSHCVKSFDETDSLCTSTFLSEDEDAPLPQRVDWRAKGYVTFVKNQGICGSCWAFSATGALEGQMFRKTGKLISLSEQQLVDCSQSFGNLGCNGGWPSKSFDYIKSSKGLEADFTYPYKARKEICRFNPQRVIATCSGFKSLPKGDENALKNAVASIGPISVLIDTSKHTFQLYKSGVYDEPGCSSTKLNHAVLLVGYDNDPTGKPYWLVKNSWGINWGDNGYIKMSRNKMNQCGIATIATYPLV 334          
BLAST of Cathepsin L2 vs. Ensembl Cavefish
Match: ENSAMXT00000042132.1 (cathepsin L1-like [Source:NCBI gene;Acc:103023924])

HSP 1 Score: 286.189 bits (731), Expect = 2.492e-94
Identity = 157/339 (46.31%), Postives = 215/339 (63.42%), Query Frame = 1
Query:   64 MNTYLATSFLICFFGKCFSLNLELND--QWRLFM-KIYNKSYENSLHEIIRREIWEDNLKYIQKHNLDHDLDLYTFTLGINQFADLTHEEFKAIYLPG-----NFTNSKTGNTYLPPLNSNELPKRVDWREKGYVTNVKNQGGCGSCYSFSATGSLEGQYFRKSKKLVSLSEQQLIDCSEK--NSGCNGGWMNNAFQDVKIMGGIDSELDYPYKGKKLQCNFQRSKAITSCNGYKNID-KNENSLAIAVANEGPISVAIDASSRSFQFYKSGVYNEPNCGVNAT-HAVLVVGYGTDGFDNYWIVKNSWSTAWGIKGYIWMSKDKNNQCIIASYASFPEV 1044
            M  +LA + L+   G   S+++E  +   W+L + K+YN + E+      R+  W  N K +  HN+  D  L T+ LG+  FAD+ ++E++ + L G     N T +   +++L       LP  VDWR +GYVT VKNQ  CGSC++FSATG+LEGQ FRK   L+ LSEQQL+DCS +  N GC+GGWMN AFQ VK  GG+D+E  YPY+  +  C +       +C+GY +I   +E +L  AVA  GP+SVAID    SFQ Y+SGVY+EP+C  +A  HAVL VGYG+D   +YW+VKNSW T WG +GYI MS++KNNQC IA+ AS+P V
Sbjct:    1 MRVFLAVATLVAVVGAA-SISMEDLEFHAWKLKLGKVYNPAEESQ-----RKITWLANRKLVLVHNMLADQGLKTYRLGMTHFADMDNQEYRQM-LQGCLGSFNETKAPGASSFLRQAGGATLPNTVDWRTQGYVTEVKNQEMCGSCWAFSATGALEGQMFRKLGYLLPLSEQQLVDCSREYGNMGCSGGWMNQAFQYVKDNGGLDTEDSYPYEAMEGYCRYYPDAVGATCSGYVDISIGDEQALQEAVATVGPVSVAIDVGHYSFQLYQSGVYDEPDCSTSALGHAVLAVGYGSDYGQDYWLVKNSWGTYWGDQGYIKMSRNKNNQCGIATAASYPLV 332          
BLAST of Cathepsin L2 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000010475.1 (pep scaffold:Pmarinus_7.0:GL482653:10321:33550:-1 gene:ENSPMAG00000009483.1 transcript:ENSPMAT00000010475.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 281.567 bits (719), Expect = 9.846e-94
Identity = 147/288 (51.04%), Postives = 190/288 (65.97%), Query Frame = 1
Query:  205 RREIWEDNLKYIQKHNLDHDLDLYTFTLGINQFADLTHEEFKAIYLP----GNFTNSKTGNTYLPPLNSNELPKRVDWREKGYVTNVKNQGGCGSCYSFSATGSLEGQYFRKSKKLVSLSEQQLIDCS--EKNSGCNGGWMNNAFQDVKIMGGIDSELDYPYKGKKLQCNFQRSKAITSCNGYKNI-DKNENSLAIAVANEGPISVAIDASSRSFQFYKSGVYNEPNCGVNATHAVLVVGYGTDGF-DNYWIVKNSWSTAWGIKGYIWMSKDKNNQCIIASYASFPEV 1044
            RR IWE NLK I  HNL+H +  +T+ +G+NQF+D+T EEF+ + L        + +  G T++ P    E P+ VDWR++GYVT++KNQG CGSC+SFS TGSLEGQ+ RK+  LVSLSEQ L+DCS  E N GCNGG M NAF  +K  GGIDSE  YPYKG+   C +          GY  I + +E +L  AVA+ GP+SVAIDAS  SFQ Y SG+Y +  C  +  HAVLVVGYG D     +W+VKNSW   WG +GY+ M++D NN C IA+ +S+P V
Sbjct:    7 RRIIWEKNLKRISVHNLEHSMGKHTWRMGMNQFSDMTGEEFQQVMLGFRGWNGTSKAPRGATFMAPAFF-EAPESVDWRKQGYVTDIKNQGDCGSCWSFSTTGSLEGQHKRKTGVLVSLSEQNLVDCSSTEGNHGCNGGLMINAFNYIKKNGGIDSEESYPYKGQVETCKYDPKNKAAEVTGYVEIPEGDEEALMNAVASVGPVSVAIDASLASFQSYGSGIYKDAMCSHHIDHAVLVVGYGVDEMGQKFWLVKNSWGVTWGEQGYVRMARDDNNLCGIATMSSYPLV 293          
BLAST of Cathepsin L2 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000006499.1 (pep scaffold:Pmarinus_7.0:GL477089:42202:47941:1 gene:ENSPMAG00000005817.1 transcript:ENSPMAT00000006499.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 280.026 bits (715), Expect = 1.734e-92
Identity = 156/316 (49.37%), Postives = 202/316 (63.92%), Query Frame = 1
Query:  133 LNDQWRLFMKIYNKSYENSLHEIIRREIWEDNLKYIQKHNLDHDLDLYTFTLGINQFADLTHEEFKAI---YLPGNFTNSKTGNTYLPPLNSNELPKRVDWREKGYVTNVKNQGGCGSCYSFSATGSLEGQYFRKSKKLVSLSEQQLIDCS--EKNSGCNGGWMNNAFQDVKIMGGIDSELDYPYKGKKL-QCNFQRSKAITSCNGYKNIDK-NENSLAIAVANEGPISVAIDASSRSFQFYKSGVYNEPNCGV-NATHAVLVVGYGTDGF----DNYWIVKNSWSTAWGIKGYIWMSKDKNNQCIIASYASFPEV 1044
            L+++W  +   + K YE    E  RR IWE NL  I+ HNL+H L  +T+ +G+N F D+T+EEF+     Y          G+T+L P N  E P  VDWR+KG VT VK+QG CGSC++FS TG+LEGQ+ RK  +LVSLSEQ L+DCS  E N GC GG M+ AFQ VK  GGIDSE  YPY G    +C++       +  G+ ++   +E +L IAVA+ GP+SVAIDAS  SFQFY+SGVY EP+C   +  H VLVVGYG  G       YWIVKNSWS  WG +GY+ M+++K N C IA+ AS+P V
Sbjct:   26 LDEEWGSWKGFHQKLYEPK-QESWRRMIWEKNLNKIKIHNLEHSLGKHTWRMGMNHFGDMTNEEFRQKMNGYHGVQPHKVSKGSTFLVPQNY-EAPPTVDWRDKGLVTEVKDQGECGSCWAFSTTGALEGQHMRKVGQLVSLSEQNLVDCSRAEGNQGCGGGLMDQAFQYVKDNGGIDSEAAYPYTGTDGDKCHYDPKFNSANDTGFVDVTSGDEKALKIAVASVGPVSVAIDASHESFQFYQSGVYFEPDCSSQDLDHGVLVVGYGVKGTGENGKKYWIVKNSWSPKWGDEGYVLMARNKKNHCGIATAASYPLV 339          
BLAST of Cathepsin L2 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000003800.1 (pep scaffold:Pmarinus_7.0:GL485125:12828:20107:1 gene:ENSPMAG00000003453.1 transcript:ENSPMAT00000003800.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 275.404 bits (703), Expect = 2.388e-91
Identity = 149/289 (51.56%), Postives = 190/289 (65.74%), Query Frame = 1
Query:  205 RREIWEDNLKYIQKHNLDHDLDLYTFTLGINQFADLTHEEFKAIYLP----GNFTNSKTGNTYLPPLNSNELPKRVDWREKGYVTNVKNQGGCGSCYSFSATGSLEGQYFRKSKKLVSLSEQQLIDCS--EKNSGCNGGWMNNAFQDVKIMGGIDSELDYPYKGKKLQ-CNFQRSKAITSCNGYKNI-DKNENSLAIAVANEGPISVAIDASSRSFQFYKSGVYNEPNCGVNATHAVLVVGYGTD-GFDNYWIVKNSWSTAWGIKGYIWMSKDKNNQCIIASYASFPEV 1044
            RR IWE NLK I  HNL+H +  +T+ +G+N+F D+T EEF+ + L        + +  G T++ P    E P+ VDWR++GYVT+VKNQG CGSC+SFS TGSLEGQ+ RK+  LVSLSEQ L+DCS  E N GCNGG M NAF  +K  GGIDSE  YPYKG+ ++ C +          GY  I + +E +L  AVA+ GP+SVAIDAS  SF +Y SG+Y +  C     HAVLVVGYG D   D +W+VKNSW   WG KGY+ M++D NN C IA  AS+P V
Sbjct:    8 RRMIWEQNLKKIAVHNLEHSMGKHTWRMGMNRFGDMTGEEFQQVMLGFRGWNGTSKAPRGATFMAPAFF-EAPESVDWRKQGYVTDVKNQGDCGSCWSFSTTGSLEGQHKRKTGVLVSLSEQNLVDCSSTEGNYGCNGGLMINAFNYIKKNGGIDSEESYPYKGQGVETCKYNPKNKAAEVTGYVEIPEGDEEALKNAVASVGPVSVAIDASLNSFLYYISGIYKDKLCSHIINHAVLVVGYGVDEKGDKFWLVKNSWGVQWGEKGYVRMARDDNNLCGIAVTASYPLV 295          
BLAST of Cathepsin L2 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000011285.1 (pep scaffold:Pmarinus_7.0:GL499136:454:1347:-1 gene:ENSPMAG00000010258.1 transcript:ENSPMAT00000011285.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 275.404 bits (703), Expect = 3.031e-91
Identity = 149/299 (49.83%), Postives = 197/299 (65.89%), Query Frame = 1
Query:  172 KSYENSLHEIIRREIWEDNLKYIQKHNLDHDLDLYTFTLGINQFADLTHEEFK--AIYLPGNFTNSKT--GNTYLPPLNSNELPKRVDWREKGYVTNVKNQGGCGSCYSFSATGSLEGQYFRKSKKLVSLSEQQLIDCS--EKNSGCNGGWMNNAFQDVKIMGGIDSELDYPYKGKKLQCNFQRSKAITSCNGYKNIDK-NENSLAIAVANEGPISVAIDASSRSFQFYKSGVYNEPNCGVNATHAVLVVGYGTDGFDN-YWIVKNSWSTAWGIKGYIWMSKDKNNQCIIASYASFPEV 1044
            K+Y+ +  E  RR IWE NLK I  HNL+H +  +T+ +G+N+F D+T EEF+   + L G+   SK   G T++ P    + P+ VDWR++GYVT+VK+QG CGSC++FS TGSLEGQ+ RK+  LVSLSEQ L+DCS  E N+GC GG M+ AF  +K  GGIDSE  YPY  K   C +          G+ +I   NE +L  AVA+ GP+S+ IDAS  SFQ Y SG+Y++ +C  N  H VLVVGYG D  +  +WIVKNSW T WG  GYI M++DK+N C IA+ AS+P V
Sbjct:    1 KTYDQN-EEGWRRMIWEKNLKKIAVHNLEHSMGKHTWRMGMNRFGDMTKEEFQHTMLGLRGSNDTSKASRGATFMAPAFF-KAPESVDWRKQGYVTDVKDQGDCGSCWAFSTTGSLEGQHKRKTGVLVSLSEQNLVDCSSAEGNNGCKGGLMDLAFTYIKKNGGIDSEASYPYTAKDENCKYNPKNKAAEDTGFVDIPSGNEEALKNAVASVGPVSIGIDASLESFQLYSSGIYSDSDCSNNLDHGVLVVGYGVDDDERKFWIVKNSWGTKWGDHGYILMARDKDNLCGIATAASYPLV 297          
BLAST of Cathepsin L2 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000007755.1 (pep scaffold:Pmarinus_7.0:GL476381:1843:17023:-1 gene:ENSPMAG00000007008.1 transcript:ENSPMAT00000007755.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 263.462 bits (672), Expect = 4.984e-86
Identity = 139/307 (45.28%), Postives = 196/307 (63.84%), Query Frame = 1
Query:  142 QWRLFMKIYNKSYENSLHEIIRREIWEDNLKYIQKHNLDHDLDLYTFTLGINQFADLTHEEFKAIYLPGNFTNSKTGNTY----LPPLNSNELPKRVDWREKGYVTNVKNQGGCGSCYSFSATGSLEGQYFRKSKKLVSLSEQQLIDCSEK--NSGCNGGWMNNAFQDVKIMGGIDSELDYPYKGKKLQCNFQRSKAITSCNGYKNIDK--NENSLAIAVANEGPISVAIDASSRSFQFYKSGVYNEPNCGVNATHAVLVVGYGTDGFDNYWIVKNSWSTAWGIKGYIWMSKDKNNQCIIASYASFP 1038
            QW  +   Y K Y +   +  RR+++E NLK + +HNL  D    +F LGIN+++DL   E+    + G F N + G        P  + + LP++VDWR KGYVT VK QG CGS ++FSATGSLEGQ+F  +  L SLSEQQL+DC++   N+GCNGG    A Q +    GIDSEL YPY+    +C F+ +   T C+ Y+ ++   NE  L  AVA+ GPI++A++A   +F+ YKSG++NEP+C  +  HA+LVVGYG+   +++WIVKNSW   WG KGYI+M ++K+NQC IAS   +P
Sbjct:   26 QWDTWKSTYGKHYGSEQEDAHRRDVFEQNLKRVLQHNLLADEGNVSFHLGINKYSDLELHEYHEKVV-GRFWNLRNGTRRRGAPFPLRSMDNLPEQVDWRLKGYVTPVKEQGLCGSSWAFSATGSLEGQHFAATGNLTSLSEQQLVDCTKSYYNNGCNGGRSERALQYIIDNNGIDSELSYPYEHADGKCRFKPANVATKCSSYQFVEPSSNEEVLRQAVASVGPIAIAMNADLDTFKHYKSGLFNEPSCDKSPNHAMLVVGYGSLSGNDFWIVKNSWGEDWGEKGYIYMIRNKDNQCGIASIGIYP 331          
BLAST of Cathepsin L2 vs. Ensembl Nematostella
Match: EDO46465 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RPY5])

HSP 1 Score: 308.531 bits (789), Expect = 1.449e-103
Identity = 157/331 (47.43%), Postives = 216/331 (65.26%), Query Frame = 1
Query:   64 MNTYLATSFLICFFGKCFSLNLELNDQWRLFMKIYNKSYENSLHEIIRREIWEDNLKYIQKHNLDHDLDLYTFTLGINQFADLTHEEFKAIYLPGNFTNSKTGNTYLPPLNSNELPKRVDWREKGYVTNVKNQGGCGSCYSFSATGSLEGQYFRKSKKLVSLSEQQLIDCSEK--NSGCNGGWMNNAFQDVKIMGGIDSELDYPYKGKKLQCNFQRSKAITSCNGYKNIDK-NENSLAIAVANEGPISVAIDASSRSFQFYKSGVYNEPNC-GVNATHAVLVVGYGTDGFDNYWIVKNSWSTAWGIKGYIWMSKDKNNQCIIASYASFPEV 1044
            M  +LA   +     +CFS  L  + QW  +   + K+Y     E +RR IW DNL+ ++KHN ++    +++ L +N FADLT  EFK  ++     ++ TG +   PL++ +LP  VDWR+KG+VT VKNQG CGSC++FS+TGSLEGQ+FRK+ KLVSLSEQ L+DCS+K  N+GC GG M+ AF+ +K   GID+E  YPY  +  QC+F+      +  GY ++ + +E  L  AVA  GPISVAIDA   SFQ YK+GVY+EP+C      H VL VGYG +   +YW+VKNSW   WG+ GYI MS++K+NQC IA+ AS+P V
Sbjct:    1 MKAFLACLLVAVLIAQCFS-ELSQDRQWHAWKDFHGKTYTGE-EEDLRRAIWNDNLEIVKKHNAEN----HSYKLDMNHFADLTVTEFKQRFMGYRAASNSTGGSTFLPLSNVQLPAEVDWRDKGFVTAVKNQGQCGSCWAFSSTGSLEGQHFRKTGKLVSLSEQNLVDCSKKYGNNGCEGGLMDYAFKYIKNNDGIDTEQSYPYTARDGQCHFKPGSVGATVTGYTDVQRGSEGDLQSAVATVGPISVAIDAGHSSFQLYKTGVYSEPDCSSTQLDHGVLAVGYGAEDGKDYWLVKNSWGEGWGMNGYIKMSRNKDNQCGIATQASYPLV 325          
BLAST of Cathepsin L2 vs. Ensembl Nematostella
Match: EDO36727 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SHX1])

HSP 1 Score: 288.5 bits (737), Expect = 1.365e-95
Identity = 152/313 (48.56%), Postives = 202/313 (64.54%), Query Frame = 1
Query:  130 ELNDQWRLFMKIYNKSYENSLHEIIRREIWEDNLKYIQKHNLDHDLDLYTFTLGINQFADLTHEEFKAIY--LPGNFTN--SKTGNTYLPPLNSNELPKRVDWREKGYVTNVKNQGGCGSCYSFSATGSLEGQYFRKSKKLVSLSEQQLIDCSEK--NSGCNGGWMNNAFQDVKIMGGIDSELDYPYKGKKLQCNFQRSKAITSCNGYKNIDK-NENSLAIAVANEGPISVAIDASSRSFQFYKSGVYNEPNCGVNA-THAVLVVGYGTDGFDNYWIVKNSWSTAWGIKGYIWMSKDKNNQCIIASYASFPEV 1044
            E   QW+ +   + K Y     E  R+ IW DNLK IQKHN +     ++FTL +N   DLT +EF+  Y  +  +++N   K G+ +L P +  ++P  VDWR++GYVT VKNQG CGSC++FS TGSLEGQ F+K+ KLVSLSEQ L+DCS    N+GC GG M+ AF+ +K  GGID+E  YPY+ +  +C FQ+S       G+ ++   +E +L  A    GPISVAIDA   SFQFY SGVYN   C   +  H VLVVGYGT    +YW+VKNSW   WG++GYI MS++KNNQC +A+ AS+P V
Sbjct:   23 EDEQQWQAWKLFHTKKYTTVTEEGARKAIWRDNLKKIQKHNAEG----HSFTLAMNHLGDLTQDEFRYFYTGMRSHYSNYTKKQGSAFLAPSHV-QVPDTVDWRKEGYVTPVKNQGQCGSCWAFSTTGSLEGQNFKKTGKLVSLSEQNLVDCSTAYGNNGCQGGLMDYAFKYIKENGGIDTEESYPYEARNDRCRFQKSNIGAVDTGFVDVTHGDEEALKTAAGTVGPISVAIDAGHMSFQFYHSGVYNNAGCSSTSLDHGVLVVGYGTYQGSDYWLVKNSWGERWGMEGYIMMSRNKNNQCGVATQASYPLV 330          
BLAST of Cathepsin L2 vs. Ensembl Nematostella
Match: EDO45953 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RRH6])

HSP 1 Score: 284.648 bits (727), Expect = 2.944e-94
Identity = 152/334 (45.51%), Postives = 213/334 (63.77%), Query Frame = 1
Query:   64 MNTYLATSFLICFFGKCFSLNLELNDQWRLFMKIYNKSYENSLHEIIRREIWEDNLKYIQKHNLDHDLDLYTFTLGINQFADLTHEEFKAIYLP--GNFTNSKTG-NTYLPPLNSNELPKRVDWREKGYVTNVKNQGGCGSCYSFSATGSLEGQYFRKSKKLVSLSEQQLIDCSEK--NSGCNGGWMNNAFQDVKIMGGIDSELDYPYKGKKLQCNFQRSKAITSCNGYKNIDK-NENSLAIAVANEGPISVAIDASSRSFQFYKSGVYNEPNC-GVNATHAVLVVGYGTDGFDNYWIVKNSWSTAWGIKGYIWMSKDKNNQCIIASYASFPEV 1044
            M  +L    L+    + +S+    + +W  +   + KSY +   E  R  IW+ NL+ I++HN +     +++ + +N   DLT +EF+  YL    +  ++K G  TY+PP N  ++P  VDW +KGYVT VKNQG CGSC++FS TGS+EGQ+FRK+  LVSLSEQ LIDCS    N+GC GG M+NAF+ ++  GGID+E  YPY G++  C+F  S       GY++I + +E +L  AVA  GP+SVA+DAS   +QFY SGVY+ P C      H VLV+GYG     +YW+VKNSW  +WG++GYI MS++KNNQC IAS AS+P V
Sbjct:    1 MKVFLVLCVLVAS-SRGWSVRFGQDSEWVAWKSYHGKSYSDVHEERTRMAIWQQNLEKIKRHNAED----HSYKMAMNHLGDLTEDEFRYFYLGVRAHHNSTKRGWATYMPPSNV-KIPSSVDWSQKGYVTGVKNQGQCGSCWAFSTTGSVEGQHFRKTGSLVSLSEQNLIDCSGSYGNNGCQGGLMDNAFRYIESNGGIDTESSYPYLGQQGSCHFSSSHVGARVTGYQDIPQGSEQALQSAVATVGPVSVAVDAS--QWQFYSSGVYDNPYCSSTQLDHGVLVIGYGNYNGQDYWLVKNSWGYSWGVEGYIMMSRNKNNQCGIASSASYPLV 326          
BLAST of Cathepsin L2 vs. Ensembl Nematostella
Match: EDO45852 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RRL9])

HSP 1 Score: 271.552 bits (693), Expect = 4.413e-89
Identity = 147/330 (44.55%), Postives = 204/330 (61.82%), Query Frame = 1
Query:   85 SFLICFFGKCFSLNLE-LNDQ-WRLFMKIYNKSYENSLHEIIRREIWEDNLKYIQKHNLDHDLDLYTFTLGINQFADLTHEEFK----AIYLPGNFTNSKTGNTYLPPLNSNELPKRVDWREKGYVTNVKNQGGCGSCYSFSATGSLEGQYFRKSKKLVSLSEQQLIDCSEK--NSGCNGGWMNNAFQDVKIMGGIDSELDYPYKGKKLQCNFQRSKAITSCNGYKNIDK-NENSLAIAVANEGPISVAIDASSRSFQFYKSGVYNEPNC-GVNATHAVLVVGYGTDGFDNYWIVKNSWSTAWGIKGYIWMSKDKNNQCIIASYASFPEV 1044
            + L+C         +E L D  W+ +   + K Y N   E +R  IW++NLK I  HN       ++F L +N   D+T  E       + L  +  +   G T+LPP N  ++   +DWR KGYVT VKNQG CGSC++FS TG+LEGQ+FRK+ KLVSLSEQ L+DCS K  N+GC GG M+NAFQ +K  GGID+E  YPY  K   C++ +S       G+ +I   +EN+L  A+A+ GPIS+AIDAS  +F FY  GVY++P+C      H VL VGYGTD   +YW+VKNSW  +WG +GYI ++++ +++C +AS AS+P V
Sbjct:    7 AVLLCISSALAMPPMEPLQDPNWKAWKSFHGKEYPNKNEETMRNFIWQNNLKKIVTHNEGK----HSFKLAMNHLGDMTSLEISQTLLGLKLKKHAESQPKGATFLPPANV-KVVDSIDWRSKGYVTPVKNQGQCGSCWAFSTTGALEGQHFRKTGKLVSLSEQNLVDCSGKYGNNGCEGGLMDNAFQYIKENGGIDTEKSYPYLAKDGVCHYNKSAIGAKDTGFVDIPTGDENALQQALASVGPISIAIDASQSTFHFYHQGVYDDPDCSSTRLDHGVLAVGYGTDDGKDYWLVKNSWGPSWGEEGYIKIARNDHDKCGVASKASYPLV 331          
BLAST of Cathepsin L2 vs. Ensembl Nematostella
Match: EDO42751 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S0K3])

HSP 1 Score: 200.29 bits (508), Expect = 5.417e-62
Identity = 110/260 (42.31%), Postives = 156/260 (60.00%), Query Frame = 1
Query:  211 EIWEDNLKYIQKHNLDHDLDLYTFTLGINQFADLTHEEF-KAIYLPGNFTNSKTGNTYLPPLNSNELPKRVDWREKGYVTNVKNQGGCGSCYSFSATGSLEGQYFRKSKKLVSLSEQQLIDCSEKNSGCNGGWMNNAFQDVKIMGGIDSELDYPYKGKKLQCNFQRSKAITSCNGYKNIDKNENSLAIAVANEGPISVAIDASSRSFQFYKSGVYNEPNCGVNAT---HAVLVVGYGTDGFDNYWIVKNSWSTAWGIKGY 978
            +I+E N++   K      +D  T   G   F+DL+ EEF K   +PG             PL   ++P+ VDWR+KG VT VKNQG CGSC++FS TG++EGQY  K+ KLVSLSEQ+L+DC   + GC GG  +NA++ ++ +GG++SE DYPYKG   +C F +++   + N    I K+E  +A  +A  GPIS+ I+A+  + QFY  G+ +      N +   H VL+VGYG      YWI+KNSW  +WG KGY
Sbjct:    2 KIFESNMRKAAKM---QKMDSGTAQYGPTIFSDLSEEEFRKQKMMPGWGKPLYEMKDAEIPLG--DIPESVDWRDKGVVTPVKNQGSCGSCWAFSTTGNIEGQYAIKTGKLVSLSEQELVDCDTIDKGCEGGLPSNAYKQIEKLGGLESESDYPYKGADSKCKFNKAEVKVTINSSVVISKDEKEIAAWLAKNGPISIGINAN--AMQFYMGGIAHPWKIFCNPSSLNHGVLIVGYGVKNGTPYWIIKNSWGPSWGEKGY 254          
BLAST of Cathepsin L2 vs. Ensembl Medaka
Match: ctsl (cathepsin L [Source:NCBI gene;Acc:100049246])

HSP 1 Score: 291.967 bits (746), Expect = 1.430e-96
Identity = 158/320 (49.38%), Postives = 212/320 (66.25%), Query Frame = 1
Query:  118 SLNLELNDQWRLFMKIYNKSYENSLHEIIRREIWEDNLKYIQKHNLDHDLDLYTFTLGINQFADLTHEEFKAIYLPGNFTNSK--TGNTYLPPLNSNELPKRVDWREKGYVTNVKNQGGCGSCYSFSATGSLEGQYFRKSKKLVSLSEQQLIDCS--EKNSGCNGGWMNNAFQDVKIMGGIDSELDYPYKGKKLQ-CNFQRSKAITSCNGYKNIDKN-ENSLAIAVANEGPISVAIDASSRSFQFYKSGVYNEPNCGVNA-THAVLVVGYGTDGFD----NYWIVKNSWSTAWGIKGYIWMSKDKNNQCIIASYASFPEV 1044
            +L+ +L+  W+L+   ++K+Y     E  RR +WE NL+ I+ HNL+H +  +++ LG+N F D+THEEF+ I         +  +G+ ++ P N  E P+ VDWR+KGYVT VK+QG CGSC++FS TG+LEGQ FRK+ KLVSLSEQ L+DCS  E N GCNGG M+ AFQ VK   G+DSE  YPYKG   Q C +    +  +  G+ +I    E +L  AVA+ GP+SVAIDA   SFQFY+SG+Y E  C  +   H VLVVGYG +G D     YWIVKNSWS  WG KG+I+M+KD++N C IA+ AS+P V
Sbjct:   19 TLDPQLDQHWQLWKGWHSKNYHEK-EEGWRRLVWEKNLRKIELHNLEHSMGKHSYRLGMNHFGDMTHEEFRQIMNGYKRREQRKYSGSLFMEP-NFLEAPRAVDWRDKGYVTPVKDQGQCGSCWAFSTTGALEGQQFRKTGKLVSLSEQNLVDCSRPEGNEGCNGGLMDQAFQYVKDNQGLDSEDFYPYKGTDDQPCQYNAQYSAVNDTGFVDIPSGKERALMKAVASVGPVSVAIDAGHESFQFYQSGIYFEKECSSDELDHGVLVVGYGFEGEDVDGKKYWIVKNSWSEKWGDKGFIYMAKDRHNHCGIATAASYPLV 336          
BLAST of Cathepsin L2 vs. Ensembl Medaka
Match: ctsl.1 (cathepsin L1 [Source:NCBI gene;Acc:101171789])

HSP 1 Score: 288.115 bits (736), Expect = 5.645e-95
Identity = 150/322 (46.58%), Postives = 211/322 (65.53%), Query Frame = 1
Query:  112 CFSLNLELND--QWRLFMKIYNKSYENSLHEIIRREIWEDNLKYIQKHNLDHDLDLYTFTLGINQFADLTHEEFKAIYLPG-----NFTNSKTGNTYLPPLNSNELPKRVDWREKGYVTNVKNQGGCGSCYSFSATGSLEGQYFRKSKKLVSLSEQQLIDCSEK--NSGCNGGWMNNAFQDVKIMGGIDSELDYPYKGKKLQCNFQRSKAITSCNGYKNIDK-NENSLAIAVANEGPISVAIDASSRSFQFYKSGVYNEPNCGVNA-THAVLVVGYGTDGFDNYWIVKNSWSTAWGIKGYIWMSKDKNNQCIIASYASFPEV 1044
            C SL+LE  +   WRL    + ++Y +   E  RR+ W +N K +  HN+  D  + ++ LG+  FAD+ +EE+K +   G     N +  + G+T+     + +LP  VDWR+KGYVT+VK+Q  CGSC++FSATGSLEGQ FRK+ KLVSLSEQQL+DCS    N GC GG M++AF+ ++  GGID+E  YPY+ +  +C ++      +C GY ++   +E++L  AVA  GPISV IDAS  SFQ Y+SG+Y+EP C  +   H VL VGYG++   +YW+VKNSW   WG +GYI MSK+K+NQC IA+ AS+P V
Sbjct:   21 CASLSLEDLEFHAWRL---KFGRTYSSPTEEAQRRQTWLNNRKLVLVHNILADQGIKSYRLGMTYFADMENEEYKRLISQGCLGSFNASLPRRGSTFFRLPENKDLPAAVDWRDKGYVTDVKDQKQCGSCWAFSATGSLEGQTFRKTGKLVSLSEQQLVDCSGDYGNMGCGGGLMDDAFRYIQATGGIDTEESYPYEAEDGECRYKPDAVGATCTGYVDVSSGDEDALQEAVATIGPISVGIDASHISFQLYESGLYDEPQCSSSELDHGVLAVGYGSENGQDYWLVKNSWGLTWGDQGYIKMSKNKSNQCGIATAASYPLV 339          
BLAST of Cathepsin L2 vs. Ensembl Medaka
Match: ctss2.1 (cathepsin S [Source:NCBI gene;Acc:101165175])

HSP 1 Score: 274.248 bits (700), Expect = 1.607e-89
Identity = 140/318 (44.03%), Postives = 198/318 (62.26%), Query Frame = 1
Query:  106 GKCFSLNLELNDQWRLFMKIYNKSYENSLHEIIRREIWEDNLKYIQKHNLDHDLDLYTFTLGINQFADLTHEE----FKAIYLPGNFTNSKTGNTYLPPLNSNELPKRVDWREKGYVTNVKNQGGCGSCYSFSATGSLEGQYFRKSKKLVSLSEQQLIDCSEK--NSGCNGGWMNNAFQDVKIMGGIDSELDYPYKGKKLQCNFQRSKAITSCNGYKNI-DKNENSLAIAVANEGPISVAIDASSRSFQFYKSGVYNEPNCGVNATHAVLVVGYGTDGFDNYWIVKNSWSTAWGIKGYIWMSKDKNNQCIIASYASFP 1038
            G   + +  L+  W L+ K ++K Y +   ++ RR++WE NL  I  HNL++ + L+T+ L +N   DLT EE    F ++  P N    +  + ++    SN +P  +DWR+K  VT+VK QG CGSC++FSA G+LEGQ  RK+ KLV LS Q L+DCS K  N GCNGG+M+ AFQ V    GIDS+  YPY G    C++       +C+ Y  + + +E +L  A+A  GPISVAIDA+   F FY+SGVY++ +C  N  H VL VGYGT    +YW+VKNSW T +G +GYI M+++KN+QC IA Y  +P
Sbjct:   22 GAASAFDSRLDIHWELWKKTHSKHYPSEEEDVHRRDLWERNLMLITMHNLEYSMGLHTYDLSMNHMGDLTQEEILQQFASLRPPTNL--KREPHLFVGASGSNNIPDEMDWRQKNCVTSVKMQGSCGSCWAFSAVGALEGQLCRKTGKLVDLSPQNLVDCSSKYGNHGCNGGFMHQAFQYVIDNQGIDSDAGYPYVGVTQNCHYSSEYRAANCSQYSFLPEGDEGALKEAIATIGPISVAIDATRPRFAFYRSGVYDDSSCSQNVNHGVLAVGYGTLNGQDYWLVKNSWGTTFGEQGYIRMARNKNDQCGIAMYGCYP 337          
BLAST of Cathepsin L2 vs. Ensembl Medaka
Match: ctss (cathepsin S [Source:NCBI gene;Acc:100049247])

HSP 1 Score: 272.707 bits (696), Expect = 4.599e-89
Identity = 145/321 (45.17%), Postives = 194/321 (60.44%), Query Frame = 1
Query:   88 FLICFFGKCFSLNLELNDQWRLFMKIYNKSYENSLHEIIRREIWEDNLKYIQKHNLDHDLDLYTFTLGINQFADLTHEEFKAIYLPGNFTNSKTGNTYLPPLNSN-ELPKRVDWREKGYVTNVKNQGGCGSCYSFSATGSLEGQYFRKSKKLVSLSEQQLIDCSEK--NSGCNGGWMNNAFQDVKIMGGIDSELDYPYKGKKLQCNFQRSKAITSCNGYKNIDK-NENSLAIAVANEGPISVAIDASSRSFQFYKSGVYNEPNCGVNATHAVLVVGYGTDGFDNYWIVKNSWSTAWGIKGYIWMSKDKNNQCIIASYASFP 1038
            F     G   ++   L+  W L+ K Y+K+Y + + E  RR IWE+NL+ I  HNL+  L L+++ L +N   DLT EE  A  L G          +   +  N  +P+ VDWRE G VT+VK QG CGSC++FSA G+LEGQ  + +  L SLS Q L+DCS K  N GC GG+M+NAFQ V    GI S+  YPY GK+ +C +       +C GY  + K +E +L + VA  GPISVAIDAS   F FY+ GVY + +C  N  H VLVVGYGT+  ++YW+VKNSW   +G  GYI M++++ NQC IA YA FP
Sbjct:    6 FFTVLCGFVPAVRSHLDQHWNLWKKTYSKTYSHEIEEFGRRRIWEENLEMISVHNLEVSLGLHSYELAMNHLGDLTIEELIA-SLTGTVAPVGLERIHYDLVKINTSVPESVDWREGGLVTSVKTQGRCGSCWAFSAVGALEGQLKKTTGILTSLSPQNLVDCSTKYGNYGCKGGFMSNAFQYVIKNQGISSDAAYPYIGKRDKCKYDSKHRAANCTGYNFLPKGDEFALKVGVATIGPISVAIDASRPKFLFYRHGVYKDHSCSHNVNHGVLVVGYGTENGEDYWLVKNSWGERYGDGGYIKMARNRRNQCGIALYACFP 325          
BLAST of Cathepsin L2 vs. Ensembl Medaka
Match: ctsk (cathepsin K [Source:NCBI gene;Acc:101164922])

HSP 1 Score: 266.159 bits (679), Expect = 1.585e-86
Identity = 138/313 (44.09%), Postives = 193/313 (61.66%), Query Frame = 1
Query:  133 LNDQWRLFMKIYNKSYENSLHEIIRREIWEDNLKYIQKHNLDHDLDLYTFTLGINQFADLTHEE----FKAIYLPGNFTNSKTGNTYLPPLNSN----ELPKRVDWREKGYVTNVKNQGGCGSCYSFSATGSLEGQYFRKSKKLVSLSEQQLIDCSEKNSGCNGGWMNNAFQDVKIMGGIDSELDYPYKGKKLQCNFQRSKAITSCNGYKNI-DKNENSLAIAVANEGPISVAIDASSRSFQFYKSGVYNEPNCG-VNATHAVLVVGYGTDG-FDNYWIVKNSWSTAWGIKGYIWMSKDKNNQCIIASYASFP 1038
            L+  W  +   + K Y     E IRR IWE NL+ I+ HN +  L ++T+TLG+NQF D+T EE       + +P N            P+ ++    +LPK VD+R+KG VT+VKNQG CGSC++FS+ G+LEGQ  +K+  LV LS Q L+DC  +N GC GG+M NAF+ V+  GGIDSE  YPY G+   C +  S       GYK + + +E++LA+A+   GP+SV IDAS  SF +Y+ G+Y + NC   +  HAVL VGYG +     +WIVKNSW   WG KGY+ M++++ N C IA+ AS+P
Sbjct:   24 LDAHWEEWKMTHTKEYITVEEEGIRRAIWEKNLRMIEAHNQEAALGMHTYTLGMNQFGDMTQEEVVERMTGLQMPLNPEPRV-------PMETDGSLIKLPKSVDYRKKGMVTSVKNQGSCGSCWAFSSVGALEGQLAKKTGNLVDLSPQNLVDCVTENDGCGGGYMTNAFKYVQENGGIDSEAAYPYMGEDQPCRYNVSGLAAQIKGYKEVPEGDEHALAVALFKAGPVSVGIDASQNSFLYYQKGIYFDRNCNKEDINHAVLAVGYGVNAKGKKFWIVKNSWGETWGNKGYVLMARNRGNVCGIANLASYP 329          
BLAST of Cathepsin L2 vs. Planmine SMEST
Match: SMESG000049555.1 (SMESG000049555.1)

HSP 1 Score: 723.005 bits (1865), Expect = 0.000e+0
Identity = 348/348 (100.00%), Postives = 348/348 (100.00%), Query Frame = 1
Query:    1 HITCNLTQQYKTVNLYFLSLQMNTYLATSFLICFFGKCFSLNLELNDQWRLFMKIYNKSYENSLHEIIRREIWEDNLKYIQKHNLDHDLDLYTFTLGINQFADLTHEEFKAIYLPGNFTNSKTGNTYLPPLNSNELPKRVDWREKGYVTNVKNQGGCGSCYSFSATGSLEGQYFRKSKKLVSLSEQQLIDCSEKNSGCNGGWMNNAFQDVKIMGGIDSELDYPYKGKKLQCNFQRSKAITSCNGYKNIDKNENSLAIAVANEGPISVAIDASSRSFQFYKSGVYNEPNCGVNATHAVLVVGYGTDGFDNYWIVKNSWSTAWGIKGYIWMSKDKNNQCIIASYASFPEV 1044
            HITCNLTQQYKTVNLYFLSLQMNTYLATSFLICFFGKCFSLNLELNDQWRLFMKIYNKSYENSLHEIIRREIWEDNLKYIQKHNLDHDLDLYTFTLGINQFADLTHEEFKAIYLPGNFTNSKTGNTYLPPLNSNELPKRVDWREKGYVTNVKNQGGCGSCYSFSATGSLEGQYFRKSKKLVSLSEQQLIDCSEKNSGCNGGWMNNAFQDVKIMGGIDSELDYPYKGKKLQCNFQRSKAITSCNGYKNIDKNENSLAIAVANEGPISVAIDASSRSFQFYKSGVYNEPNCGVNATHAVLVVGYGTDGFDNYWIVKNSWSTAWGIKGYIWMSKDKNNQCIIASYASFPEV
Sbjct:   10 HITCNLTQQYKTVNLYFLSLQMNTYLATSFLICFFGKCFSLNLELNDQWRLFMKIYNKSYENSLHEIIRREIWEDNLKYIQKHNLDHDLDLYTFTLGINQFADLTHEEFKAIYLPGNFTNSKTGNTYLPPLNSNELPKRVDWREKGYVTNVKNQGGCGSCYSFSATGSLEGQYFRKSKKLVSLSEQQLIDCSEKNSGCNGGWMNNAFQDVKIMGGIDSELDYPYKGKKLQCNFQRSKAITSCNGYKNIDKNENSLAIAVANEGPISVAIDASSRSFQFYKSGVYNEPNCGVNATHAVLVVGYGTDGFDNYWIVKNSWSTAWGIKGYIWMSKDKNNQCIIASYASFPEV 357          
BLAST of Cathepsin L2 vs. Planmine SMEST
Match: SMESG000049555.1 (SMESG000049555.1)

HSP 1 Score: 679.863 bits (1753), Expect = 0.000e+0
Identity = 327/327 (100.00%), Postives = 327/327 (100.00%), Query Frame = 1
Query:   64 MNTYLATSFLICFFGKCFSLNLELNDQWRLFMKIYNKSYENSLHEIIRREIWEDNLKYIQKHNLDHDLDLYTFTLGINQFADLTHEEFKAIYLPGNFTNSKTGNTYLPPLNSNELPKRVDWREKGYVTNVKNQGGCGSCYSFSATGSLEGQYFRKSKKLVSLSEQQLIDCSEKNSGCNGGWMNNAFQDVKIMGGIDSELDYPYKGKKLQCNFQRSKAITSCNGYKNIDKNENSLAIAVANEGPISVAIDASSRSFQFYKSGVYNEPNCGVNATHAVLVVGYGTDGFDNYWIVKNSWSTAWGIKGYIWMSKDKNNQCIIASYASFPEV 1044
            MNTYLATSFLICFFGKCFSLNLELNDQWRLFMKIYNKSYENSLHEIIRREIWEDNLKYIQKHNLDHDLDLYTFTLGINQFADLTHEEFKAIYLPGNFTNSKTGNTYLPPLNSNELPKRVDWREKGYVTNVKNQGGCGSCYSFSATGSLEGQYFRKSKKLVSLSEQQLIDCSEKNSGCNGGWMNNAFQDVKIMGGIDSELDYPYKGKKLQCNFQRSKAITSCNGYKNIDKNENSLAIAVANEGPISVAIDASSRSFQFYKSGVYNEPNCGVNATHAVLVVGYGTDGFDNYWIVKNSWSTAWGIKGYIWMSKDKNNQCIIASYASFPEV
Sbjct:    1 MNTYLATSFLICFFGKCFSLNLELNDQWRLFMKIYNKSYENSLHEIIRREIWEDNLKYIQKHNLDHDLDLYTFTLGINQFADLTHEEFKAIYLPGNFTNSKTGNTYLPPLNSNELPKRVDWREKGYVTNVKNQGGCGSCYSFSATGSLEGQYFRKSKKLVSLSEQQLIDCSEKNSGCNGGWMNNAFQDVKIMGGIDSELDYPYKGKKLQCNFQRSKAITSCNGYKNIDKNENSLAIAVANEGPISVAIDASSRSFQFYKSGVYNEPNCGVNATHAVLVVGYGTDGFDNYWIVKNSWSTAWGIKGYIWMSKDKNNQCIIASYASFPEV 327          
BLAST of Cathepsin L2 vs. Planmine SMEST
Match: SMESG000049555.1 (SMESG000049555.1)

HSP 1 Score: 614.764 bits (1584), Expect = 0.000e+0
Identity = 296/296 (100.00%), Postives = 296/296 (100.00%), Query Frame = 1
Query:  157 MKIYNKSYENSLHEIIRREIWEDNLKYIQKHNLDHDLDLYTFTLGINQFADLTHEEFKAIYLPGNFTNSKTGNTYLPPLNSNELPKRVDWREKGYVTNVKNQGGCGSCYSFSATGSLEGQYFRKSKKLVSLSEQQLIDCSEKNSGCNGGWMNNAFQDVKIMGGIDSELDYPYKGKKLQCNFQRSKAITSCNGYKNIDKNENSLAIAVANEGPISVAIDASSRSFQFYKSGVYNEPNCGVNATHAVLVVGYGTDGFDNYWIVKNSWSTAWGIKGYIWMSKDKNNQCIIASYASFPEV 1044
            MKIYNKSYENSLHEIIRREIWEDNLKYIQKHNLDHDLDLYTFTLGINQFADLTHEEFKAIYLPGNFTNSKTGNTYLPPLNSNELPKRVDWREKGYVTNVKNQGGCGSCYSFSATGSLEGQYFRKSKKLVSLSEQQLIDCSEKNSGCNGGWMNNAFQDVKIMGGIDSELDYPYKGKKLQCNFQRSKAITSCNGYKNIDKNENSLAIAVANEGPISVAIDASSRSFQFYKSGVYNEPNCGVNATHAVLVVGYGTDGFDNYWIVKNSWSTAWGIKGYIWMSKDKNNQCIIASYASFPEV
Sbjct:    1 MKIYNKSYENSLHEIIRREIWEDNLKYIQKHNLDHDLDLYTFTLGINQFADLTHEEFKAIYLPGNFTNSKTGNTYLPPLNSNELPKRVDWREKGYVTNVKNQGGCGSCYSFSATGSLEGQYFRKSKKLVSLSEQQLIDCSEKNSGCNGGWMNNAFQDVKIMGGIDSELDYPYKGKKLQCNFQRSKAITSCNGYKNIDKNENSLAIAVANEGPISVAIDASSRSFQFYKSGVYNEPNCGVNATHAVLVVGYGTDGFDNYWIVKNSWSTAWGIKGYIWMSKDKNNQCIIASYASFPEV 296          
BLAST of Cathepsin L2 vs. Planmine SMEST
Match: SMESG000049781.1 (SMESG000049781.1)

HSP 1 Score: 481.485 bits (1238), Expect = 2.339e-171
Identity = 227/327 (69.42%), Postives = 263/327 (80.43%), Query Frame = 1
Query:   64 MNTYLATSFLICFFGKCFSLNLELNDQWRLFMKIYNKSYENSLHEIIRREIWEDNLKYIQKHNLDHDLDLYTFTLGINQFADLTHEEFKAIYLPGNFTNSKTGNTYLPPLNSNELPKRVDWREKGYVTNVKNQGGCGSCYSFSATGSLEGQYFRKSKKLVSLSEQQLIDCSEKNSGCNGGWMNNAFQDVKIMGGIDSELDYPYKGKKLQCNFQRSKAITSCNGYKNIDKNENSLAIAVANEGPISVAIDASSRSFQFYKSGVYNEPNCGVNATHAVLVVGYGTDGFDNYWIVKNSWSTAWGIKGYIWMSKDKNNQCIIASYASFPEV 1044
            M     T +L+ FF    +LNLELNDQW+L+MKIYNK+YEN  HE+IRR IWEDNLKYI KHNLDHDL LYTFTLGINQFADLTH EFKAIYL GN   +KTGNTYLPPLN+  +P  VDW EKGYVT+VK+QG CGSC++FSATGSLEGQ+FRK+ +LVS SEQQL+DCS+ N+GC+GG M +AF D+K +GGI+SE +YPYK ++L C F  SK +TS +GYK ID+NE SLAIAVANEGPISV I   S +FQ YKSGVYNEP+C     H VLVVGYGT   DNYWIVKNSW   WG+KGYIWMSKDK+NQC IAS+ASFP V
Sbjct:    1 MRILTVTPYLLSFFAISIALNLELNDQWKLYMKIYNKTYENPFHELIRRMIWEDNLKYIHKHNLDHDLGLYTFTLGINQFADLTHAEFKAIYLSGNLKPTKTGNTYLPPLNAFNVPANVDWTEKGYVTDVKDQGKCGSCWAFSATGSLEGQFFRKTGRLVSFSEQQLVDCSKSNNGCHGGLMTSAFNDIKDLGGIESEQEYPYKAQQLNCEFNHSKVVTSVSGYKEIDENEGSLAIAVANEGPISVGISV-SLNFQLYKSGVYNEPDCSRVPNHGVLVVGYGTSVNDNYWIVKNSWGPLWGMKGYIWMSKDKDNQCAIASFASFPVV 326          
BLAST of Cathepsin L2 vs. Planmine SMEST
Match: SMESG000049783.1 (SMESG000049783.1)

HSP 1 Score: 480.715 bits (1236), Expect = 4.461e-171
Identity = 228/327 (69.72%), Postives = 264/327 (80.73%), Query Frame = 1
Query:   64 MNTYLATSFLICFFGKCFSLNLELNDQWRLFMKIYNKSYENSLHEIIRREIWEDNLKYIQKHNLDHDLDLYTFTLGINQFADLTHEEFKAIYLPGNFTNSKTGNTYLPPLNSNELPKRVDWREKGYVTNVKNQGGCGSCYSFSATGSLEGQYFRKSKKLVSLSEQQLIDCSEKNSGCNGGWMNNAFQDVKIMGGIDSELDYPYKGKKLQCNFQRSKAITSCNGYKNIDKNENSLAIAVANEGPISVAIDASSRSFQFYKSGVYNEPNCGVNATHAVLVVGYGTDGFDNYWIVKNSWSTAWGIKGYIWMSKDKNNQCIIASYASFPEV 1044
            M     T +L+ FF    +LNLELNDQW+L+MKIYNK+YEN  HE+IRR IWEDNLKYI KHNLDHDL LYTFTLGINQFADLTH EFKAIYL GN   +KTGNTYLPPLN+  +P  VDW EKGYVT+VK+QG CGSC++FS TGSLEGQ+FRK+ +LVS SEQQL+DCS+ N+GCNGG M +AF D+K +GGI+SE +YPY+ ++L C F RSK +TS +GYK I KNE SLAIAVANEGPISV I   S +FQ YKSGVYNEP+C     HAVLVVGYGT   DNYWIVKNSW  +WG+KGYIWMSKDK+NQC IAS+ASFP V
Sbjct:    1 MRILTVTPYLLSFFAISIALNLELNDQWKLYMKIYNKTYENPFHELIRRMIWEDNLKYIHKHNLDHDLGLYTFTLGINQFADLTHAEFKAIYLSGNLRPTKTGNTYLPPLNAFNVPANVDWTEKGYVTDVKDQGNCGSCWAFSTTGSLEGQFFRKTGRLVSFSEQQLVDCSKSNNGCNGGLMTSAFNDIKDLGGIESEQEYPYQAQQLNCVFNRSKVVTSVSGYKEIYKNEGSLAIAVANEGPISVLIRV-SLNFQLYKSGVYNEPDCSRVPNHAVLVVGYGTSVNDNYWIVKNSWGPSWGMKGYIWMSKDKDNQCAIASFASFPIV 326          
The following BLAST results are available for this feature:
BLAST of Cathepsin L2 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5
Match NameE-valueIdentityDescription
CTSL6.795e-9645.18cathepsin L [Source:HGNC Symbol;Acc:HGNC:2537][more]
CTSL6.795e-9645.18cathepsin L [Source:HGNC Symbol;Acc:HGNC:2537][more]
CTSK7.503e-9648.70cathepsin K [Source:HGNC Symbol;Acc:HGNC:2536][more]
CTSV1.978e-9148.73cathepsin V [Source:HGNC Symbol;Acc:HGNC:2538][more]
CTSV1.978e-9148.73cathepsin V [Source:HGNC Symbol;Acc:HGNC:2538][more]
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BLAST of Cathepsin L2 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 5
Match NameE-valueIdentityDescription
cpl-18.277e-8745.34CathePsin L family [Source:UniProtKB/TrEMBL;Acc:H... [more]
cpl-16.736e-6552.28CathePsin L family [Source:UniProtKB/TrEMBL;Acc:H... [more]
cpl-16.736e-6552.28CathePsin L family [Source:UniProtKB/TrEMBL;Acc:H... [more]
tag-1961.018e-5937.97pep chromosome:WBcel235:V:8594914:8597500:1 gene:W... [more]
tag-1961.018e-5937.97pep chromosome:WBcel235:V:8594914:8597469:1 gene:W... [more]
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BLAST of Cathepsin L2 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Cp14.267e-9448.42gene:FBgn0013770 transcript:FBtr0087592[more]
Cp18.819e-9448.42gene:FBgn0013770 transcript:FBtr0087593[more]
Cp11.300e-9248.43gene:FBgn0013770 transcript:FBtr0339955[more]
Cp17.018e-8152.34gene:FBgn0013770 transcript:FBtr0304021[more]
CG121637.541e-6138.36gene:FBgn0260462 transcript:FBtr0078822[more]
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BLAST of Cathepsin L2 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
ctsla2.667e-10149.12cathepsin La [Source:ZFIN;Acc:ZDB-GENE-030131-106][more]
ctsla2.667e-10149.12cathepsin La [Source:ZFIN;Acc:ZDB-GENE-030131-106][more]
si:dkey-239j18.29.699e-9948.06si:dkey-239j18.2 [Source:ZFIN;Acc:ZDB-GENE-121214-... [more]
si:dkey-239j18.29.699e-9948.06si:dkey-239j18.2 [Source:ZFIN;Acc:ZDB-GENE-121214-... [more]
zgc:1748558.976e-9848.90zgc:174855 [Source:ZFIN;Acc:ZDB-GENE-071004-74][more]
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BLAST of Cathepsin L2 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5
Match NameE-valueIdentityDescription
ctsk8.633e-9746.81cathepsin K (pycnodysostosis) [Source:NCBI gene;Ac... [more]
ctsk8.843e-9746.81cathepsin K (pycnodysostosis) [Source:NCBI gene;Ac... [more]
fcrl29.919e-9650.48Fc receptor-like 2 [Source:Xenbase;Acc:XB-GENE-590... [more]
fcrl21.324e-9550.48Fc receptor-like 2 [Source:Xenbase;Acc:XB-GENE-590... [more]
ano12.368e-8742.22anoctamin 1, calcium activated chloride channel [S... [more]
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BLAST of Cathepsin L2 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Ctsk1.520e-9447.78cathepsin K [Source:MGI Symbol;Acc:MGI:107823][more]
Ctsl2.701e-9247.40cathepsin L [Source:MGI Symbol;Acc:MGI:88564][more]
Ctsl2.701e-9247.40cathepsin L [Source:MGI Symbol;Acc:MGI:88564][more]
Ctss4.049e-9045.05cathepsin S [Source:MGI Symbol;Acc:MGI:107341][more]
Ctss4.666e-9045.05cathepsin S [Source:MGI Symbol;Acc:MGI:107341][more]
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BLAST of Cathepsin L2 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|Q9GL24|CATL1_CANLF1.156e-9750.16Cathepsin L1 OS=Canis lupus familiaris OX=9615 GN=... [more]
sp|Q9GKL8|CATL1_CHLAE9.287e-9746.08Cathepsin L1 OS=Chlorocebus aethiops OX=9534 GN=CT... [more]
sp|P07711|CATL1_HUMAN3.263e-9545.18Cathepsin L1 OS=Homo sapiens OX=9606 GN=CTSL PE=1 ... [more]
sp|P43235|CATK_HUMAN3.603e-9548.70Cathepsin K OS=Homo sapiens OX=9606 GN=CTSK PE=1 S... [more]
sp|P43236|CATK_RABIT4.428e-9548.42Cathepsin K OS=Oryctolagus cuniculus OX=9986 GN=CT... [more]
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BLAST of Cathepsin L2 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
A0A2U8U4477.486e-11655.17Cathepsin L2 OS=Dugesia japonica OX=6161 PE=2 SV=1[more]
A0A267H1I67.831e-11054.17Uncharacterized protein OS=Macrostomum lignano OX=... [more]
A0A1I8GVB79.220e-11054.17Uncharacterized protein OS=Macrostomum lignano OX=... [more]
A0A147BAD24.135e-10748.51Cathepsin l (Fragment) OS=Carios mimon OX=360319 P... [more]
A0A1Z5KUE47.847e-10749.40Uncharacterized protein (Fragment) OS=Ornithodoros... [more]
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BLAST of Cathepsin L2 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
si:dkey-26g8.56.342e-10150.30cathepsin L1-like [Source:NCBI gene;Acc:103028700][more]
ctss2.11.856e-9746.73cathepsin S [Source:NCBI gene;Acc:103044830][more]
ctsla6.007e-9549.10cathepsin L1-like [Source:NCBI gene;Acc:103043056][more]
ENSAMXT00000001970.21.080e-9449.05cathepsin L1-like [Source:NCBI gene;Acc:103022163][more]
ENSAMXT00000042132.12.492e-9446.31cathepsin L1-like [Source:NCBI gene;Acc:103023924][more]
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BLAST of Cathepsin L2 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 5
Match NameE-valueIdentityDescription
ENSPMAT00000010475.19.846e-9451.04pep scaffold:Pmarinus_7.0:GL482653:10321:33550:-1 ... [more]
ENSPMAT00000006499.11.734e-9249.37pep scaffold:Pmarinus_7.0:GL477089:42202:47941:1 g... [more]
ENSPMAT00000003800.12.388e-9151.56pep scaffold:Pmarinus_7.0:GL485125:12828:20107:1 g... [more]
ENSPMAT00000011285.13.031e-9149.83pep scaffold:Pmarinus_7.0:GL499136:454:1347:-1 gen... [more]
ENSPMAT00000007755.14.984e-8645.28pep scaffold:Pmarinus_7.0:GL476381:1843:17023:-1 g... [more]
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BLAST of Cathepsin L2 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Cathepsin L2 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 5
Match NameE-valueIdentityDescription
EDO464651.449e-10347.43Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO367271.365e-9548.56Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO459532.944e-9445.51Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO458524.413e-8944.55Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO427515.417e-6242.31Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
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BLAST of Cathepsin L2 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5
Match NameE-valueIdentityDescription
ctsl1.430e-9649.38cathepsin L [Source:NCBI gene;Acc:100049246][more]
ctsl.15.645e-9546.58cathepsin L1 [Source:NCBI gene;Acc:101171789][more]
ctss2.11.607e-8944.03cathepsin S [Source:NCBI gene;Acc:101165175][more]
ctss4.599e-8945.17cathepsin S [Source:NCBI gene;Acc:100049247][more]
ctsk1.585e-8644.09cathepsin K [Source:NCBI gene;Acc:101164922][more]
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BLAST of Cathepsin L2 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5
Match NameE-valueIdentityDescription
SMESG000049555.10.000e+0100.00SMESG000049555.1[more]
SMESG000049555.10.000e+0100.00SMESG000049555.1[more]
SMESG000049555.10.000e+0100.00SMESG000049555.1[more]
SMESG000049781.12.339e-17169.42SMESG000049781.1[more]
SMESG000049783.14.461e-17169.72SMESG000049783.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30013826 ID=SMED30013826|Name=Cathepsin L2|organism=Schmidtea mediterranea sexual|type=transcript|length=1161bp
CATATAACATGCAATTTAACGCAACAATATAAAACTGTCAACTTGTATTT
CCTGTCATTACAAATGAATACTTACCTTGCAACTTCATTTTTGATTTGTT
TCTTTGGAAAATGTTTCTCATTAAATCTTGAGCTGAATGACCAATGGAGA
CTTTTCATGAAGATCTACAATAAAAGTTATGAGAATTCTCTTCATGAGAT
AATTCGCAGAGAGATATGGGAAGACAATTTGAAATACATCCAAAAACACA
ATCTTGATCATGATCTAGACTTGTATACGTTTACATTGGGCATCAATCAG
TTCGCCGACTTGACTCATGAAGAATTCAAAGCGATTTATCTGCCGGGAAA
TTTCACAAACAGTAAAACTGGAAATACATATTTACCACCTTTGAATTCAA
ATGAGTTACCAAAAAGAGTAGACTGGAGAGAGAAAGGATATGTTACAAAT
GTGAAGAATCAAGGTGGCTGTGGCAGCTGTTATTCATTTTCGGCAACAGG
AAGTCTAGAAGGACAATATTTCCGTAAATCAAAAAAATTGGTCAGTTTGT
CCGAACAGCAGTTGATTGATTGTAGCGAAAAAAATTCTGGGTGCAATGGT
GGCTGGATGAATAATGCGTTTCAAGATGTTAAAATTATGGGAGGAATAGA
TTCAGAACTGGATTATCCTTATAAAGGAAAGAAATTACAATGCAACTTTC
AACGTTCAAAAGCCATCACTTCTTGCAATGGCTACAAAAATATAGATAAA
AATGAAAATAGTTTAGCTATTGCAGTTGCCAATGAAGGACCTATATCTGT
TGCAATCGACGCATCTTCGAGAAGCTTTCAGTTTTATAAATCAGGAGTTT
ATAACGAACCTAATTGTGGTGTTAACGCTACTCATGCCGTATTGGTCGTT
GGATACGGCACGGATGGATTTGATAACTATTGGATCGTGAAAAACAGTTG
GAGCACGGCTTGGGGAATCAAAGGTTACATCTGGATGAGCAAAGATAAGA
ACAATCAATGTATAATTGCGTCTTATGCCAGTTTTCCGGAAGTTTGATGT
TTCTAACCATGGATTCTATATTTCTCACTTTTTATTTAATTATGTAGTAA
TTATGTAGTAATTTTGGCTTGTAATTAGTATGTTATTTCTGAACATGTCG
TGTTTCTTAAA
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protein sequence of SMED30013826-orf-1

>SMED30013826-orf-1 ID=SMED30013826-orf-1|Name=SMED30013826-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=349bp
HITCNLTQQYKTVNLYFLSLQMNTYLATSFLICFFGKCFSLNLELNDQWR
LFMKIYNKSYENSLHEIIRREIWEDNLKYIQKHNLDHDLDLYTFTLGINQ
FADLTHEEFKAIYLPGNFTNSKTGNTYLPPLNSNELPKRVDWREKGYVTN
VKNQGGCGSCYSFSATGSLEGQYFRKSKKLVSLSEQQLIDCSEKNSGCNG
GWMNNAFQDVKIMGGIDSELDYPYKGKKLQCNFQRSKAITSCNGYKNIDK
NENSLAIAVANEGPISVAIDASSRSFQFYKSGVYNEPNCGVNATHAVLVV
GYGTDGFDNYWIVKNSWSTAWGIKGYIWMSKDKNNQCIIASYASFPEV*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0003116parenchymal cell
Vocabulary: INTERPRO
TermDefinition
IPR039417Peptidase_C1A_papain-like
IPR038765Papain-like_cys_pep_sf
IPR000668Peptidase_C1A_C
IPR013201Prot_inhib_I29
IPR025660Pept_his_AS
IPR025661Pept_asp_AS
IPR000169Pept_cys_AS
Vocabulary: molecular function
TermDefinition
GO:0008234cysteine-type peptidase activity
GO:0008233peptidase activity
GO:0016787hydrolase activity
Vocabulary: biological process
TermDefinition
GO:0006508proteolysis
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR000668Peptidase C1A, papain C-terminalPRINTSPR00705PAPAINcoord: 310..316
score: 79.08
coord: 295..305
score: 61.95
coord: 154..169
score: 55.02
IPR000668Peptidase C1A, papain C-terminalSMARTSM00645pept_c1coord: 136..347
e-value: 1.1E-105
score: 367.1
IPR000668Peptidase C1A, papain C-terminalPFAMPF00112Peptidase_C1coord: 136..346
e-value: 7.1E-78
score: 261.6
IPR013201Cathepsin propeptide inhibitor domain (I29)SMARTSM00848Inhibitor_I29_2coord: 49..109
e-value: 2.4E-25
score: 100.2
IPR013201Cathepsin propeptide inhibitor domain (I29)PFAMPF08246Inhibitor_I29coord: 49..109
e-value: 5.3E-15
score: 55.6
NoneNo IPR availableGENE3DG3DSA:3.90.70.10coord: 41..348
e-value: 4.2E-109
score: 366.9
NoneNo IPR availablePANTHERPTHR12411:SF631coord: 39..346
NoneNo IPR availablePANTHERPTHR12411CYSTEINE PROTEASE FAMILY C1-RELATEDcoord: 39..346
NoneNo IPR availableTMHMMTMhelixcoord: 13..35
IPR000169Cysteine peptidase, cysteine active sitePROSITEPS00139THIOL_PROTEASE_CYScoord: 154..165
IPR025661Cysteine peptidase, asparagine active sitePROSITEPS00640THIOL_PROTEASE_ASNcoord: 310..329
IPR025660Cysteine peptidase, histidine active sitePROSITEPS00639THIOL_PROTEASE_HIScoord: 293..303
IPR039417Papain-like cysteine endopeptidaseCDDcd02248Peptidase_C1Acoord: 137..346
e-value: 2.72234E-107
score: 310.71
IPR038765Papain-like cysteine peptidase superfamilySUPERFAMILYSSF54001Cysteine proteinasescoord: 40..346