Unc-5 netrin receptor B
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Overview
Neoblast Clusters
Zeng et. al., 2018▻ Overview▻ Neoblast Population▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Overview
Single cell RNA-seq of pluripotent neoblasts and its early progeniesWe isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)Explore this single cell expression dataset with our NB Cluster Shiny App
Neoblast Population
Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Embryonic Expression
Davies et. al., 2017
Hover the mouse over a column in the graph to view average RPKM values per sample. Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult. back to top Anatomical Expression
PAGE et. al., 2020SMED30013824 has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGEPAGE Curations: 9
Homology
BLAST of Unc-5 netrin receptor B vs. Ensembl Human
Match: UNC5B (unc-5 netrin receptor B [Source:HGNC Symbol;Acc:HGNC:12568]) HSP 1 Score: 307.76 bits (787), Expect = 2.733e-88 Identity = 286/1046 (27.34%), Postives = 452/1046 (43.21%), Query Frame = 3
Query: 300 WDSKENHEVDSKKDLVLPSE---KHLEGVPKFIQQPKSMYYVSKSHPAVITCIAQPVSHVNIFCADKQYSYMNEEVSATGLKVIKMDNEGRLAVKGNRWKFSLEVQHKDVIEWFS--EYRCHCEAWNQIEQLQKVKKVESSSAVIYDSYINKDFKTVPKNQKVSVRGSVKLSCIPPDAKPPAEIHWVKNGEKITGKSHPQFEINEYGELLLSNIRLTDSGNYSCVASSFGLERHAT-AQILVFEVGQWSDWSEWTGICPNICSKGSNCPKVCSTSRQQRVRYCNQIK--NQKANCIGSEIEYKRCDLICDPN-LWTFWSEWSKCSGNPCKKERTRQCTT---NNCGKASS---VEIDNCTLAECGGFVASFINSNKKYPESSTSIYITHDVAMYIGLFVAVSVF---LMVVAIIFCLIRRRVIGFSPNRVWRYSTTANGIQMFYPDXXXXXXXXXXXXXXXXXXDINQPSLYRSIVLPNSLPFLPSNQSDASSNSAYTDVGNDITYIQRNHLPSLPMIATPLLSSMKPTLKIRPSYSDSKVSSTLYPQMGLVKHVSTLPI-PVSSSLSD-----HYQELGNTDNETSDQSVTEPCLPYNFNGENMIWATIDSSGGRISLALSDINLTCPPNSFAPGISEPIFLATCNSEQDLPNLSANETLLSPVVVCGPTNVIAFKPFILNIPHCAYNTDSGNWAISVLTSYSPLKQKPYWQKYLDLDAEDKDSPPGYAQLAKDRLFLITNQLQRFCVVGSSYRNKRATKVLRIA----AYCTGLDRRHADEQIVVRLYLIPDIAECISKVHNFETNRLGARLVTNQKQFFCEDEAGNITVVISDLA-MDWQASSANNYQEIPFKDVWHS--PTLHCSFNFIKRLINANSSELKISVNSLDFNWFCTLSIYQTNSHHNKQTVLLSTPNGSSHTSISATSTQFSNYSAGGSQSFPYFVDDCSKTNFESVFKLPEQTKIKLCKLLDSLTPLDNDWRQLARHLSITRSLQFFSNKLSSTEILLDLWEAQNHSRKSLNNLIDILRKMGRLDCVAILEKD 3344
WD + + VLP E +P F+Q+P+ Y V K+ P + C A P + + C + ++ N+ V+ GL D L V+ + +EV + V E F +Y C C AW+ +S A + +Y+ K+F P ++V + V L C PP+ P AE+ W+KN + I F + L++ RL+D+ NY+CVA + +R +T A ++V+ G WS W+EW+ C N C +G Q+R R C N A C G + C IC + WT WS+WS CS C R+R+C N G+ S ++ NCT C + + N E+S D A+Y GL VA+ V LM V ++ + RR F + + G F+P +N +++ N PS D ++++ + Y ++ +PM +PLL + P+LK++ YS S S GL L + P + SD H+ L + + S Q + P P + + T GGR+S+ + ++L P + G ++L +E LP +T+LSP V CGPT ++ +P IL +PHCA + +W + T + +W++ + LD E ++P Y QL ++ +QL + G SY ++ A K L++A A CT L + +R+Y + D + +V E LG LV K +D N+ + + DL W++ YQEIPF +W LHC+F + + + KI V ++ I+Q + T L TP GS T SA + + +Q PY FK+P + K+C LD+ NDWR LA+ LS+ R L +F+ K S T ++LDLWEA LN+L L +MG+ + + + D
Sbjct: 19 WDPRLSQAGTDSGSEVLPDSFPSAPAEPLPYFLQEPQDAYIV-KNKPVELRCRAFPATQIYFKC-NGEWVSQNDHVTQEGL-----DEATGLRVR----EVQIEVSRQQVEELFGLEDYWCQCVAWS------SAGTTKSRRAYVRIAYLRKNFDQEPLGKEVPLDHEVLLQCRPPEGVPVAEVEWLKNEDVIDPTQDTNFLLTIDHNLIIRQARLSDTANYTCVAKNIVAKRRSTTATVIVYVNGGWSSWAEWS-PCSNRCGRG----------WQKRTRTCTNPAPLNGGAFCEGQAFQKTACTTICPVDGAWTEWSKWSACS-TECAHWRSRECMAPPPQNGGRDCSGTLLDSKNCTDGLCMQNKKTLSDPNSHLLEASG------DAALYAGLVVAIFVVVAILMAVGVV--VYRRNCRDFDTDITDSSAALTGG---FHP--------------------VN----FKTARPSNPQLLHPSVPPDLTASAG---IYRGPVYALQDSTDKIPMTNSPLLDPL-PSLKVK-VYSSSTTGSG----PGLADGADLLGVLPPGTYPSDFARDTHFLHL-RSASLGSQQLLGLPRDP-----GSSVSGTFGCLGGRLSIPGTGVSLLVPNGAIPQGKFYEMYLLINKAESTLPLSEGTQTVLSPSVTCGPTGLLLCRPVILTMPHCA-EVSARDWIFQLKTQ----AHQGHWEEVVTLDEETLNTP-CYCQLEPRACHILLDQLGTYVFTGESY-SRSAVKRLQLAVFAPALCTSL-------EYSLRVYCLEDTPVALKEVLELERT-LGGYLVEEPKPLMFKDSYHNLRLSLHDLPHAHWRSKLLAKYQEIPFYHIWSGSQKALHCTFTLERHSLASTELTCKICVRQVEGEG----QIFQLH------TTLAETPAGSLDTLCSAPGSTVT------TQLGPY------------AFKIPLSIRQKICNSLDAPNSRGNDWRMLAQKLSMDRYLNYFATKASPTGVILDLWEALQQDDGDLNSLASALEEMGKSEMLVAVATD 942
BLAST of Unc-5 netrin receptor B vs. Ensembl Human
Match: UNC5B (unc-5 netrin receptor B [Source:HGNC Symbol;Acc:HGNC:12568]) HSP 1 Score: 302.753 bits (774), Expect = 1.187e-86 Identity = 283/1046 (27.06%), Postives = 449/1046 (42.93%), Query Frame = 3
Query: 300 WDSKENHEVDSKKDLVLPSE---KHLEGVPKFIQQPKSMYYVSKSHPAVITCIAQPVSHVNIFCADKQYSYMNEEVSATGLKVIKMDNEGRLAVKGNRWKFSLEVQHKDVIEWFS--EYRCHCEAWNQIEQLQKVKKVESSSAVIYDSYINKDFKTVPKNQKVSVRGSVKLSCIPPDAKPPAEIHWVKNGEKITGKSHPQFEINEYGELLLSNIRLTDSGNYSCVASSFGLERHAT-AQILVFEVGQWSDWSEWTGICPNICSKGSNCPKVCSTSRQQRVRYCNQIK--NQKANCIGSEIEYKRCDLICDPN-LWTFWSEWSKCSGNPCKKERTRQCTT---NNCGKASS---VEIDNCTLAECGGFVASFINSNKKYPESSTSIYITHDVAMYIGLFVAVSVF---LMVVAIIFCLIRRRVIGFSPNRVWRYSTTANGIQMFYPDXXXXXXXXXXXXXXXXXXDINQPSLYRSIVLPNSLPFLPSNQSDASSNSAYTDVGNDITYIQRNHLPSLPMIATPLLSSMKPTLKIRPSYSDSKVSSTLYPQMGLVKHVSTLPI-PVSSSLSD-----HYQELGNTDNETSDQSVTEPCLPYNFNGENMIWATIDSSGGRISLALSDINLTCPPNSFAPGISEPIFLATCNSEQDLPNLSANETLLSPVVVCGPTNVIAFKPFILNIPHCAYNTDSGNWAISVLTSYSPLKQKPYWQKYLDLDAEDKDSPPGYAQLAKDRLFLITNQLQRFCVVGSSYRNKRATKVLRIA----AYCTGLDRRHADEQIVVRLYLIPDIAECISKVHNFETNRLGARLVTNQKQFFCEDEAGNITVVISDLA-MDWQASSANNYQEIPFKDVWHS--PTLHCSFNFIKRLINANSSELKISVNSLDFNWFCTLSIYQTNSHHNKQTVLLSTPNGSSHTSISATSTQFSNYSAGGSQSFPYFVDDCSKTNFESVFKLPEQTKIKLCKLLDSLTPLDNDWRQLARHLSITRSLQFFSNKLSSTEILLDLWEAQNHSRKSLNNLIDILRKMGRLDCVAILEKD 3344
WD + + VLP E +P F+Q+P+ Y V K+ P + C A P + + C + ++ N+ V+ GL D L V+ + +EV + V E F +Y C C AW+ +S A + +Y+ K+F P ++V + V L C PP+ P AE+ W+KN + I F + L++ RL+D+ NY+CVA + +R +T A ++V+ G WS W+EW+ C N C +G Q+R R C N A C G + C IC + WT WS+WS CS C R+R+C N G+ S ++ NCT C + + + D A+Y GL VA+ V LM V ++ + RR F + + G F+P +N +++ N PS D ++++ + Y ++ +PM +PLL + P+LK++ YS S S GL L + P + SD H+ L + + S Q + P P + + T GGR+S+ + ++L P + G ++L +E LP +T+LSP V CGPT ++ +P IL +PHCA + +W + T + +W++ + LD E ++P Y QL ++ +QL + G SY ++ A K L++A A CT L + +R+Y + D + +V E LG LV K +D N+ + + DL W++ YQEIPF +W LHC+F + + + KI V ++ I+Q + T L TP GS T SA + + +Q PY FK+P + K+C LD+ NDWR LA+ LS+ R L +F+ K S T ++LDLWEA LN+L L +MG+ + + + D
Sbjct: 19 WDPRLSQAGTDSGSEVLPDSFPSAPAEPLPYFLQEPQDAYIV-KNKPVELRCRAFPATQIYFKC-NGEWVSQNDHVTQEGL-----DEATGLRVR----EVQIEVSRQQVEELFGLEDYWCQCVAWS------SAGTTKSRRAYVRIAYLRKNFDQEPLGKEVPLDHEVLLQCRPPEGVPVAEVEWLKNEDVIDPTQDTNFLLTIDHNLIIRQARLSDTANYTCVAKNIVAKRRSTTATVIVYVNGGWSSWAEWS-PCSNRCGRG----------WQKRTRTCTNPAPLNGGAFCEGQAFQKTACTTICPVDGAWTEWSKWSACS-TECAHWRSRECMAPPPQNGGRDCSGTLLDSKNCTDGLCMQMLEA-----------------SGDAALYAGLVVAIFVVVAILMAVGVV--VYRRNCRDFDTDITDSSAALTGG---FHP--------------------VN----FKTARPSNPQLLHPSVPPDLTASAG---IYRGPVYALQDSTDKIPMTNSPLLDPL-PSLKVK-VYSSSTTGSG----PGLADGADLLGVLPPGTYPSDFARDTHFLHL-RSASLGSQQLLGLPRDP-----GSSVSGTFGCLGGRLSIPGTGVSLLVPNGAIPQGKFYEMYLLINKAESTLPLSEGTQTVLSPSVTCGPTGLLLCRPVILTMPHCA-EVSARDWIFQLKTQ----AHQGHWEEVVTLDEETLNTP-CYCQLEPRACHILLDQLGTYVFTGESY-SRSAVKRLQLAVFAPALCTSL-------EYSLRVYCLEDTPVALKEVLELERT-LGGYLVEEPKPLMFKDSYHNLRLSLHDLPHAHWRSKLLAKYQEIPFYHIWSGSQKALHCTFTLERHSLASTELTCKICVRQVEGEG----QIFQLH------TTLAETPAGSLDTLCSAPGSTVT------TQLGPY------------AFKIPLSIRQKICNSLDAPNSRGNDWRMLAQKLSMDRYLNYFATKASPTGVILDLWEALQQDDGDLNSLASALEEMGKSEMLVAVATD 931
BLAST of Unc-5 netrin receptor B vs. Ensembl Human
Match: UNC5C (unc-5 netrin receptor C [Source:HGNC Symbol;Acc:HGNC:12569]) HSP 1 Score: 276.559 bits (706), Expect = 9.072e-78 Identity = 254/1012 (25.10%), Postives = 438/1012 (43.28%), Query Frame = 3
Query: 369 EGVPKFIQQPKSMYYVSKSHPAVITCIAQPVSHVNIFCADKQYSYMNEEVSATGLKVIKMDNEGRLAVKGNRWKFSLEVQHKDVIEWFS--EYRCHCEAWNQIEQLQKVKKVESSSAVIYDSYINKDFKTVPKNQKVSVRGSVKLSCIPPDAKPPAEIHWVKNGEKITGKSHPQFEINEYGELLLSNIRLTDSGNYSCVASSFGLERHA-TAQILVFEVGQWSDWSEWTGICPNICSKGSNCPKVCSTSRQQRVRYCNQIK--NQKANCIGSEIEYKRCDLICDPN-LWTFWSEWSKCSGNPCKKERTRQCTT---NNCGKASS---VEIDNCTLAECGGFVASFINSNKKYPESSTSIYITHDVAMYIGLFVAVSVFLMVVAIIFCLIRRRVIGFSPNRVWRYSTTANGIQMFYPDXXXXXXXXXXXXXXXXXXDI-NQPSLYRSIVLPNSLPFLPSNQSDASSNSAYTDVGNDITYIQRNHLPSLPMIATPLLSSMKPTLKIRPSYSDSKVSSTLYPQMGLVKHVSTLPIPVSSSLSDHYQELGNTDNETSDQSVTEPCLPYNFNGENMIWATIDSSGGRISLALSDINLTCPPNSFAPGISEPIFLATCNSEQDLPNLSANETLLSPVVVCGPTNVIAFKPFILNIPHCAYNTDSGNWAISVLTSYSPLKQKPYWQKYLDLDAEDKDSPPGYAQLAKDRLFLITNQLQRFCVVGSSYRNKRATKVLRIAAY----CTGLDRRHADEQIVVRLYLIPDIAECISKVHNFETNRLGARLVTNQKQFFCEDEAGNITVVISDLAMD-WQASSANNYQEIPFKDVWHSP--TLHCSFNFIKRLINANSSELKISVNSLDFNWFCTLSIYQTNSHHNKQTVLLSTPNGSSHTSISATSTQFSNYSAGGSQSFPYFVDDCSKTNFESVFKLPEQTKIKLCKLLDSLTPLDNDWRQLARHLSITRSLQFFSNKLSSTEILLDLWEAQNHSRKSLNNLIDILRKMGRLDCVAILEKD 3344
E +P F+ +P+ Y V K+ P + C A P + + C + ++ + + + ++D L V+ + S+E+ + V E F +Y C C AW+ +S A + +Y+ K F+ P ++VS+ V L C PP+ P AE+ W+KN + I F I L++ RL+D+ NY+CVA + +R + TA ++V+ G WS W+EW+ +C + C +G Q+R R C N A C G ++ C +C + WT WS+WS C G C R R+CT N GK ++ NCT C + P+S DVA+Y+G+ +AV V L + ++ + R+ + + S G Q + + D+ + ++YR V A DV + I PM +P+L + P LKI+ + V+ PQ L + S L ++ SL ++ E + N++ + C + + +S GG + + S ++L P + G +++ E P + ++TLL+PVV CGP + +P +L + HCA + ++ +W I +L + + Q W+ + + E+ + P Y QL + ++T L + +VG S K A K L++A + C+ L+ +R+Y + D + + ++ + E ++G +L+ K + N+ + I D+A W++ YQEIPF VW LHC+F + +N K+ V ++ I+Q N +++ + P +I+ + S F +P + KLC LD+ +DWR LA L++ R L +F+ K S T ++LDLWEAQN +L+ L +L +MGR + V L +
Sbjct: 18 EPLPHFLIEPEEAYIV-KNKPVNLYCKASPATQIYFKC-NSEWVHQKDHIVDE-----RVDETSGLIVR----EVSIEISRQQVEELFGPEDYWCQCVAWS------SAGTTKSRKAYVRIAYLRKTFEQEPLGKEVSLEQEVLLQCRPPEGIPVAEVEWLKNEDIIDPVEDRNFYITIDHNLIIKQARLSDTANYTCVAKNIVAKRKSTTATVIVYVNGGWSTWTEWS-VCNSRCGRG----------YQKRTRTCTNPAPLNGGAFCEGQSVQKIACTTLCPVDGRWTPWSKWSTC-GTECTHWRRRECTAPAPKNGGKDCDGLVLQSKNCTDGLC----------MQTAPDSD-------DVALYVGIVIAVIVCLAISVVVALFVYRKNHRDFESDIIDSSALNGGFQ-------PVNIKAARQDLLAVPPDLTSAAAMYRGPVY------------------ALHDVSDKI-----------PMTNSPILDPL-PNLKIKVYNTSGAVT----PQDDLSEFTSKLSPQMTQSLLEN--EALSLKNQSLARQTDPSCTAF---------GSFNSLGGHLIVPNSGVSLLIPAGAIPQGRVYEMYVTVHRKETMRPPMDDSQTLLTPVVSCGPPGALLTRPVVLTMHHCA-DPNTEDWKI-LLKNQAAQGQ---WEDVV-VVGEENFTTPCYIQLDAEACHILTENLSTYALVGHS-TTKAAAKRLKLAIFGPLCCSSLEYS-------IRVYCLDDTQDALKEILHLE-RQMGGQLLEEPKALHFKGSTHNLRLSIHDIAHSLWKSKLLAKYQEIPFYHVWSGSQRNLHCTFTLERFSLNTVELVCKLCVRQVEGEG----QIFQLNCTVSEEPTGIDLPLLDPANTITTVTG-------------------------PSAFSIPLPIRQKLCSSLDAPQTRGHDWRMLAHKLNLDRYLNYFATKSSPTGVILDLWEAQNFPDGNLSMLAAVLEEMGRHETVVSLAAE 887
BLAST of Unc-5 netrin receptor B vs. Ensembl Human
Match: UNC5C (unc-5 netrin receptor C [Source:HGNC Symbol;Acc:HGNC:12569]) HSP 1 Score: 276.944 bits (707), Expect = 1.537e-77 Identity = 254/1012 (25.10%), Postives = 438/1012 (43.28%), Query Frame = 3
Query: 369 EGVPKFIQQPKSMYYVSKSHPAVITCIAQPVSHVNIFCADKQYSYMNEEVSATGLKVIKMDNEGRLAVKGNRWKFSLEVQHKDVIEWFS--EYRCHCEAWNQIEQLQKVKKVESSSAVIYDSYINKDFKTVPKNQKVSVRGSVKLSCIPPDAKPPAEIHWVKNGEKITGKSHPQFEINEYGELLLSNIRLTDSGNYSCVASSFGLERHA-TAQILVFEVGQWSDWSEWTGICPNICSKGSNCPKVCSTSRQQRVRYCNQIK--NQKANCIGSEIEYKRCDLICDPN-LWTFWSEWSKCSGNPCKKERTRQCTT---NNCGK---ASSVEIDNCTLAECGGFVASFINSNKKYPESSTSIYITHDVAMYIGLFVAVSVFLMVVAIIFCLIRRRVIGFSPNRVWRYSTTANGIQMFYPDXXXXXXXXXXXXXXXXXXDI-NQPSLYRSIVLPNSLPFLPSNQSDASSNSAYTDVGNDITYIQRNHLPSLPMIATPLLSSMKPTLKIRPSYSDSKVSSTLYPQMGLVKHVSTLPIPVSSSLSDHYQELGNTDNETSDQSVTEPCLPYNFNGENMIWATIDSSGGRISLALSDINLTCPPNSFAPGISEPIFLATCNSEQDLPNLSANETLLSPVVVCGPTNVIAFKPFILNIPHCAYNTDSGNWAISVLTSYSPLKQKPYWQKYLDLDAEDKDSPPGYAQLAKDRLFLITNQLQRFCVVGSSYRNKRATKVLRIAAY----CTGLDRRHADEQIVVRLYLIPDIAECISKVHNFETNRLGARLVTNQKQFFCEDEAGNITVVISDLAMD-WQASSANNYQEIPFKDVWHSP--TLHCSFNFIKRLINANSSELKISVNSLDFNWFCTLSIYQTNSHHNKQTVLLSTPNGSSHTSISATSTQFSNYSAGGSQSFPYFVDDCSKTNFESVFKLPEQTKIKLCKLLDSLTPLDNDWRQLARHLSITRSLQFFSNKLSSTEILLDLWEAQNHSRKSLNNLIDILRKMGRLDCVAILEKD 3344
E +P F+ +P+ Y V K+ P + C A P + + C + ++ + + + ++D L V+ + S+E+ + V E F +Y C C AW+ +S A + +Y+ K F+ P ++VS+ V L C PP+ P AE+ W+KN + I F I L++ RL+D+ NY+CVA + +R + TA ++V+ G WS W+EW+ +C + C +G Q+R R C N A C G ++ C +C + WT WS+WS C G C R R+CT N GK ++ NCT C + P+S DVA+Y+G+ +AV V L + ++ + R+ + + S G Q + + D+ + ++YR V A DV + I PM +P+L + P LKI+ + V+ PQ L + S L ++ SL ++ E + N++ + C + + +S GG + + S ++L P + G +++ E P + ++TLL+PVV CGP + +P +L + HCA + ++ +W I +L + + Q W+ + + E+ + P Y QL + ++T L + +VG S K A K L++A + C+ L+ +R+Y + D + + ++ + E ++G +L+ K + N+ + I D+A W++ YQEIPF VW LHC+F + +N K+ V ++ I+Q N +++ + P +I+ + S F +P + KLC LD+ +DWR LA L++ R L +F+ K S T ++LDLWEAQN +L+ L +L +MGR + V L +
Sbjct: 59 EPLPHFLIEPEEAYIV-KNKPVNLYCKASPATQIYFKC-NSEWVHQKDHIVDE-----RVDETSGLIVR----EVSIEISRQQVEELFGPEDYWCQCVAWS------SAGTTKSRKAYVRIAYLRKTFEQEPLGKEVSLEQEVLLQCRPPEGIPVAEVEWLKNEDIIDPVEDRNFYITIDHNLIIKQARLSDTANYTCVAKNIVAKRKSTTATVIVYVNGGWSTWTEWS-VCNSRCGRG----------YQKRTRTCTNPAPLNGGAFCEGQSVQKIACTTLCPVDGRWTPWSKWSTC-GTECTHWRRRECTAPAPKNGGKDCDGLVLQSKNCTDGLC----------MQTAPDSD-------DVALYVGIVIAVIVCLAISVVVALFVYRKNHRDFESDIIDSSALNGGFQ-------PVNIKAARQDLLAVPPDLTSAAAMYRGPVY------------------ALHDVSDKI-----------PMTNSPILDPL-PNLKIKVYNTSGAVT----PQDDLSEFTSKLSPQMTQSLLEN--EALSLKNQSLARQTDPSCTAF---------GSFNSLGGHLIVPNSGVSLLIPAGAIPQGRVYEMYVTVHRKETMRPPMDDSQTLLTPVVSCGPPGALLTRPVVLTMHHCA-DPNTEDWKI-LLKNQAAQGQ---WEDVV-VVGEENFTTPCYIQLDAEACHILTENLSTYALVGHS-TTKAAAKRLKLAIFGPLCCSSLEYS-------IRVYCLDDTQDALKEILHLE-RQMGGQLLEEPKALHFKGSTHNLRLSIHDIAHSLWKSKLLAKYQEIPFYHVWSGSQRNLHCTFTLERFSLNTVELVCKLCVRQVEGEG----QIFQLNCTVSEEPTGIDLPLLDPANTITTVTG-------------------------PSAFSIPLPIRQKLCSSLDAPQTRGHDWRMLAHKLNLDRYLNYFATKSSPTGVILDLWEAQNFPDGNLSMLAAVLEEMGRHETVVSLAAE 928
BLAST of Unc-5 netrin receptor B vs. Ensembl Human
Match: UNC5C (unc-5 netrin receptor C [Source:HGNC Symbol;Acc:HGNC:12569]) HSP 1 Score: 197.978 bits (502), Expect = 6.399e-52 Identity = 200/792 (25.25%), Postives = 351/792 (44.32%), Query Frame = 3
Query: 369 EGVPKFIQQPKSMYYVSKSHPAVITCIAQPVSHVNIFCADKQYSYMNEEVSATGLKVIKMDNEGRLAVKGNRWKFSLEVQHKDVIEWFS--EYRCHCEAWNQIEQLQKVKKVESSSAVIYDSYINKDFKTVPKNQKVSVRGSVKLSCIPPDAKPPAEIHWVKNGEKITGKSHPQFEINEYGELLLSNIRLTDSGNYSCVASSFGLERHAT-AQILVFEVGQWSDWSEWTGICPNICSKGSNCPKVCSTSRQQRVRYCNQIK--NQKANCIGSEIEYKRCDLICDPN-LWTFWSEWSKCSGNPCKKERTRQCTT---NNCGKASS---VEIDNCTLAECGGFVASFINSNKKYPESS----------TSIYITHDVAMYIGLFVAVSVFLMVVAIIFCLI-RRRVIGFSPNRVWRYSTTANGIQMFYPDXXXXXXXXXXXXXXXXXXDI-NQPSLYRSIVLPNSLPFLPSNQSDASSNSAYTDVGNDITYIQRNHLPSLPMIATPLLSSMKPTLKIRPSYSDSKVSSTLYPQMGLVKHVSTLPIPVSSSLSDHYQELGNTDNETSDQSVTEPCLPYNFNGENMIWATIDSSGGRISLALSDINLTCPPNSFAPGISEPIFLATCNSEQDLPNLSANETLLSPVVVCGPTNVIAFKPFILNIPHCAYNTDSGNWAISVLTSYSPLKQKPYWQKYLDLDAEDKDSPPGYAQLAKDRLFLITNQLQRFCVVGSSYRNKRATKVLRIAAY----CTGLDRRHADEQIVVRLYLIPDIAECISKVHNFETNRLGARLV 2660
E +P F+ +P+ Y V K+ P + C A P + + C + ++ + + + ++D L V+ + S+E+ + V E F +Y C C AW+ +S A + +Y+ K F+ P ++VS+ V L C PP+ P AE+ W+KN + I F I L++ RL+D+ NY+CVA + +R +T A ++V+ G WS W+EW+ +C + C +G Q+R R C N A C G ++ C +C + WT WS+WS C G C R R+CT N GK ++ NCT C + SFI YP S+ +S + DVA+Y+G+ +AV V L + ++ + R+ F + + S+ NG F P + + D+ + ++YR V A DV + I PM +P+L + P LKI+ + V+ PQ L + S L ++ SL ++ E + N++ + C + + +S GG + + S ++L P + G +++ E P + ++TLL+PVV CGP + +P +L + HCA + ++ +W I +L + + Q W+ + + E+ + P Y QL + ++T L + +VG S K A K L++A + C+ L+ +R+Y + D + + ++ + E ++G +L+
Sbjct: 59 EPLPHFLIEPEEAYIV-KNKPVNLYCKASPATQIYFKC-NSEWVHQKDHIVDE-----RVDETSGLIVR----EVSIEISRQQVEELFGPEDYWCQCVAWS------SAGTTKSRKAYVRIAYLRKTFEQEPLGKEVSLEQEVLLQCRPPEGIPVAEVEWLKNEDIIDPVEDRNFYITIDHNLIIKQARLSDTANYTCVAKNIVAKRKSTTATVIVYVNGGWSTWTEWS-VCNSRCGRG----------YQKRTRTCTNPAPLNGGAFCEGQSVQKIACTTLCPVDGRWTPWSKWSTC-GTECTHWRRRECTAPAPKNGGKDCDGLVLQSKNCTDGLC---MQSFI-----YPISTEQRTQNEYGFSSAPDSDDVALYVGIVIAVIVCLAISVVVALFVYRKNHRDFESDII--DSSALNG--GFQP----VNIKAARQDLLAVPPDLTSAAAMYRGPVY------------------ALHDVSDKI-----------PMTNSPILDPL-PNLKIKVYNTSGAVT----PQDDLSEFTSKLSPQMTQSLLEN--EALSLKNQSLARQTDPSCTAF---------GSFNSLGGHLIVPNSGVSLLIPAGAIPQGRVYEMYVTVHRKETMRPPMDDSQTLLTPVVSCGPPGALLTRPVVLTMHHCA-DPNTEDWKI-LLKNQAAQGQ---WEDVV-VVGEENFTTPCYIQLDAEACHILTENLSTYALVGHS-TTKAAAKRLKLAIFGPLCCSSLEYS-------IRVYCLDDTQDALKEILHLE-RQMGGQLL 745
BLAST of Unc-5 netrin receptor B vs. Ensembl Celegans
Match: unc-5 (Netrin receptor unc-5 [Source:UniProtKB/Swiss-Prot;Acc:Q26261]) HSP 1 Score: 170.244 bits (430), Expect = 7.113e-43 Identity = 246/1033 (23.81%), Postives = 409/1033 (39.59%), Query Frame = 3
Query: 393 QPKSMYYVSKSHPAVITCIAQPVSHVNIFCADKQYSYMNEEVSATGLKVIKMDNEGRLAVKGNRWKFSLEVQHKDVIE--WFSEYRCHCEAWNQIEQLQKVKKVESSSAVIYDSYINKDFKTVPKNQKVSVRGSVKLSCIPPDAKPPAEIHWVKNGEKITGKSHPQFEINEY--GELLLSNIRLTDSGNYSCVASSFGLERHAT-AQILVFEVGQWSDWSEWTGICPNICSKGSNCPKVCSTS-----------RQQRVRYCNQIK--NQKANCIGSEIEYKRCDLICD-PNLWTFWSEWSKCSGNPCKKERTRQCTT---NNCGK---ASSVEIDNCTLAECGGFVASFINSNKKYPESSTSIYITHDVAMYIGLFVAVSVFLMVVAIIFCLIRRRVIGFSPNRVWRY-STTANGIQMFYPDXXXXXXXXXXXXXXXXXXDINQPSLYRSIVLPNSLPFLPSNQSDASSNSAYTDVGNDITYIQRNHLPSLPMIATPLLSSMKPTLKIRPSY---SDSKVSSTLYPQMGLVKHVSTLPIPVSSSLSDHYQELGNTDNETSDQSVTEPCLPYNFNGENMIWATIDSSGGR-ISLALSDINLTCPPN--SFAPGISEPIFLATCNSEQDLPNLSANETLLSPVVVCGPTNVIAFKPFILNIPHCAYNTDSGNWAISVLTSYSPLKQKPYWQKYLDLDAEDKDS-------PPGYAQLAKDRLFLITNQLQRFCVVGSSYRNK-RATKVLRIAAYCTGLDRRHADEQ-IVVRLYLIPDIAECISKVHNFETNRLGARLVTNQKQFFCEDEAGNITVVISDLAMDWQASSANNYQEIPFKDVWH----SPTLHCSFNFIKRLINANSSELKISVNSLDFNWFCTLSIYQTNSHHNKQTVLLSTPNGSSHTSISATSTQFSNYSAGGSQSFPYFVDDCSKTNFESVFKLPEQTKIKLCKLLDSLTPLDNDWRQLARHLSITRSLQFFSN--KLSSTEILLDLWEAQNH-SRKSLNNLIDILRKMGRLDCVAILEKDL 3347
QPKS Y + ++ P + C A + + C+ K E K+I D+ + S+++ DV ++C C A +Q V S A ++ +Y+ K F P Q+V +++L C P++ P AE+ W K+G + P + G L++S RL+DSGNY+C A++ R ++ ++ G WS+WS W G C +CP + + Q+R R CN N C G E + C + C W+ WS+WS CS + C + RTR CT N G+ + C C + + S+ S SI+I V+ F++ + +FC R P + + S A GI P + L + + + + LP+S L S +S S S+ + G+ IQ ++ S K T+ +R S SD +TLY M + S L + S ++ D+ + S+++ +G +I + G + + LA+SD LT P+ +S I + C+ ++SA++ +L +P +++ HCA NW ++ + WQK + + E+ ++ PG ++T L R + G RN A K + +A + G A + +R+Y +P+ + V E G+RL+ F +E GN+ + I D+ + S + + + + H LHCS F + IN + ++ V YQ S S+ + S + Y A + K + F+LP K +L +LLD +DWR LA+ L R LQFF++ S T +LLDLWEA + S +++ +L+ LR MGR D V +LE+ L
Sbjct: 9 QPKSGYVI-RNKPLRLQCRANHATKIRYKCSSKWIDDSRIE------KLIGTDSTSGVGY----IDASVDISRIDVDTSGHVDAFQCQCYASGDDDQ----DVVASDVATVHLAYMRKHFLKSPVAQRVQEGTTLQLPCQAPESDPKAELTWYKDGVVV----QPDANVIRASDGSLIMSAARLSDSGNYTCEATNVANSRKTDPVEVQIYVDGGWSEWSPWIGTC------HVDCPLLRQHAHRIRDPHDVLPHQRRTRTCNNPAPLNDGEYCKGEEEMTRSCKVPCKLDGGWSSWSDWSACSSS-CHRYRTRACTVPPPMNGGQPCFGDDLMTQECPAQLCTADSSRIVISDTAVYGSVASIFI-------------VASFILAILAMFCCKRGNSKKSKPLKPQKMNSEKAGGIYYSEPPGVRRLLLEHQHGTLLGEKISSCSQYFEPPPLPHST-TLRSGKSAFSGYSSTRNAGSRAALIQE-------CSSSSSGSGGKRTM-LRTSSSNCSDDDNYATLYDYM---EDKSVLGLDTSQNIV-----AAQIDSNGARLSLSK-------SGARLIVPELAVEGEKMLYLAVSD-TLTDQPHLKPIESALSPVIVIGQCDV-----SMSAHDNILR-------------RPVVVSFRHCASTFPRDNWQFTLYAD-----EGSGWQKAVTIGEENLNTNMFVQFEQPGKKNDGFGWCHVMTYSLARLMLAGHPRRNSLSAAKRVHLAVF--GPTEMSAYRRPFELRVYCVPETGAAMESVWKQED---GSRLLCESNDFIL-NEKGNLCICIEDVIPGF---SCDGPEVVEISETQHRFVAQNGLHCSLKFRPKEINGSQFSTRVIV-------------YQKAS--------------STEPMVMEVSNEPELYDATSEER--------EKGSVCVEFRLPFGVKDELARLLDMPNESHSDWRGLAKKLHYDRYLQFFASFPDCSPTSLLLDLWEASSSGSARAVPDLLQTLRVMGRPDAVMVLERFL 910
BLAST of Unc-5 netrin receptor B vs. Ensembl Celegans
Match: unc-5 (Netrin receptor unc-5 [Source:UniProtKB/Swiss-Prot;Acc:Q26261]) HSP 1 Score: 167.548 bits (423), Expect = 4.811e-42 Identity = 248/1033 (24.01%), Postives = 410/1033 (39.69%), Query Frame = 3
Query: 393 QPKSMYYVSKSHPAVITCIAQPVSHVNIFCADKQYSYMNEEVSATGLKVIKMDNEGRLAVKGNRWKFSLEVQHKDVIE--WFSEYRCHCEAWNQIEQLQKVKKVESSSAVIYDSYINKDFKTVPKNQKVSVRGSVKLSCIPPDAKPPAEIHWVKNGEKITGKSHPQFEI--NEYGELLLSNIRLTDSGNYSCVASSFGLERHAT-AQILVFEVGQWSDWSEWTGICPNICSKGSNCPKVCSTS-----------RQQRVRYCNQIK--NQKANCIGSEIEYKRCDLICD-PNLWTFWSEWSKCSGNPCKKERTRQCTT---NNCGK---ASSVEIDNCTLAECGGFVASFINSNKKYPESSTSIYITHDVAMYIGLFVAVSVFLMVVAIIFCLIRRRVIGFSPNRVWRY-STTANGIQMFYPDXXXXXXXXXXXXXXXXXXDINQPSLYRSIVLPNSLPFLPSNQSDASSNSAYTDVGNDITYIQRNHLPSLPMIATPLLSSMKPTLKIRPSY---SDSKVSSTLYPQMGLVKHVSTLPIPVSSSLSDHYQELGNTDNETSDQSVTEPCLPYNFNGENMIWATIDSSGGR-ISLALSDINLTCPPN--SFAPGISEPIFLATCNSEQDLPNLSANETLLSPVVVCGPTNVIAFKPFILNIPHCAYNTDSGNWAISVLTSYSPLKQKPYWQKYLDLDAEDKDS-------PPGYAQLAKDRLFLITNQLQRFCVVGSSYRNK-RATKVLRIAAYCTGLDRRHADEQ-IVVRLYLIPDIAECISKVHNFETNRLGARLVTNQKQFFCEDEAGNITVVISDLAMDWQASSANNYQEIPFKDVWH----SPTLHCSFNFIKRLINANSSELKISVNSLDFNWFCTLSIYQTNSHHNKQTVLLSTPNGSSHTSISATSTQFSNYSAGGSQSFPYFVDDCSKTNFESVFKLPEQTKIKLCKLLDSLTPLDNDWRQLARHLSITRSLQFFSN--KLSSTEILLDLWEAQNH-SRKSLNNLIDILRKMGRLDCVAILEKDL 3347
QPKS Y + ++ P + C A + + C+ K E K+I D+ + S+++ DV ++C C A +Q V S A ++ +Y+ K F P Q+V +++L C P++ P AE+ W K+G + P + G L++S RL+DSGNY+C A++ R ++ ++ G WS+WS W G C +CP + + Q+R R CN N C G E + C + C W+ WS+WS CS + C + RTR CT N G+ + C C + + S+ S SI+I V+ F++ + +FC R P + + S A GI P + L + + + + LP+S L S +S S S+ + G+ IQ ++ S K T+ +R S SD +TLY M + S L + S ++ D+ + S+++ +G +I + G + + LA+SD LT P+ +S I + C+ ++SA++ +L V V++F+ HCA NW ++ + WQK + + E+ ++ PG ++T L R + G RN A K + +A + G A + +R+Y +P+ + V E G+RL+ F +E GN+ + I D+ + S + + + + H LHCS F + IN + ++ V YQ S S+ + S + Y A + K + F+LP K +L +LLD +DWR LA+ L R LQFF++ S T +LLDLWEA + S +++ +L+ LR MGR D V +LE+ L
Sbjct: 37 QPKSGYVI-RNKPLRLQCRANHATKIRYKCSSKWIDDSRIE------KLIGTDSTSGVGY----IDASVDISRIDVDTSGHVDAFQCQCYASGDDDQ----DVVASDVATVHLAYMRKHFLKSPVAQRVQEGTTLQLPCQAPESDPKAELTWYKDGVVV----QPDANVIRASDGSLIMSAARLSDSGNYTCEATNVANSRKTDPVEVQIYVDGGWSEWSPWIGTC------HVDCPLLRQHAHRIRDPHDVLPHQRRTRTCNNPAPLNDGEYCKGEEEMTRSCKVPCKLDGGWSSWSDWSACSSS-CHRYRTRACTVPPPMNGGQPCFGDDLMTQECPAQLCTADSSRIVISDTAVYGSVASIFI-------------VASFILAILAMFCCKRGNSKKSKPLKPQKMNSEKAGGIYYSEPPGVRRLLLEHQHGTLLGEKISSCSQYFEPPPLPHST-TLRSGKSAFSGYSSTRNAGSRAALIQE-------CSSSSSGSGGKRTM-LRTSSSNCSDDDNYATLYDYM---EDKSVLGLDTSQNIV-----AAQIDSNGARLSLSK-------SGARLIVPELAVEGEKMLYLAVSD-TLTDQPHLKPIESALSPVIVIGQCDV-----SMSAHDNILRRPV------VVSFR-------HCASTFPRDNWQFTLYAD-----EGSGWQKAVTIGEENLNTNMFVQFEQPGKKNDGFGWCHVMTYSLARLMLAGHPRRNSLSAAKRVHLAVF--GPTEMSAYRRPFELRVYCVPETGAAMESVWKQED---GSRLLCESNDFIL-NEKGNLCICIEDVIPGF---SCDGPEVVEISETQHRFVAQNGLHCSLKFRPKEINGSQFSTRVIV-------------YQKAS--------------STEPMVMEVSNEPELYDATSEER--------EKGSVCVEFRLPFGVKDELARLLDMPNESHSDWRGLAKKLHYDRYLQFFASFPDCSPTSLLLDLWEASSSGSARAVPDLLQTLRVMGRPDAVMVLERFL 938
BLAST of Unc-5 netrin receptor B vs. Ensembl Celegans
Match: unc-5 (Netrin receptor unc-5 [Source:UniProtKB/Swiss-Prot;Acc:Q26261]) HSP 1 Score: 156.762 bits (395), Expect = 7.904e-39 Identity = 223/917 (24.32%), Postives = 369/917 (40.24%), Query Frame = 3
Query: 732 INKDFKTVPKNQKVSVRGSVKLSCIPPDAKPPAEIHWVKNGEKITGKSHPQFEINEY--GELLLSNIRLTDSGNYSCVASSFGLERHAT-AQILVFEVGQWSDWSEWTGICPNICSKGSNCPKVCSTS-----------RQQRVRYCNQIK--NQKANCIGSEIEYKRCDLICD-PNLWTFWSEWSKCSGNPCKKERTRQCTT---NNCGKASSVEIDNCTLAECGGFVASFINSNKKYPESSTSIYITHDVAMY--IGLFVAVSVFLMVVAIIFCLIRRRVIGFSPNRVWRY-STTANGIQMFYPDXXXXXXXXXXXXXXXXXXDINQPSLYRSIVLPNSLPFLPSNQSDASSNSAYTDVGNDITYIQRNHLPSLPMIATPLLSSMKPTLKIRPSY---SDSKVSSTLYPQMGLVKHVSTLPIPVSSSLSDHYQELGNTDNETSDQSVTEPCLPYNFNGENMIWATIDSSGGR-ISLALSDINLTCPPN--SFAPGISEPIFLATCNSEQDLPNLSANETLLSPVVVCGPTNVIAFKPFILNIPHCAYNTDSGNWAISVLTSYSPLKQKPYWQKYLDLDAEDKDS-------PPGYAQLAKDRLFLITNQLQRFCVVGSSYRNK-RATKVLRIAAYCTGLDRRHADEQ-IVVRLYLIPDIAECISKVHNFETNRLGARLVTNQKQFFCEDEAGNITVVISDLAMDWQASSANNYQEIPFKDVWH----SPTLHCSFNFIKRLINANSSELKISVNSLDFNWFCTLSIYQTNSHHNKQTVLLSTPNGSSHTSISATSTQFSNYSAGGSQSFPYFVDDCSKTNFESVFKLPEQTKIKLCKLLDSLTPLDNDWRQLARHLSITRSLQFFSN--KLSSTEILLDLWEAQNH-SRKSLNNLIDILRKMGRLDCVAILEKDL 3347
+ K F P Q+V +++L C P++ P AE+ W K+G + P + G L++S RL+DSGNY+C A++ R ++ ++ G WS+WS W G C +CP + + Q+R R CN N C G E + C + C W+ WS+WS CS + C + RTR CT N G+ D+ EC + + + +S + D A+Y + V+ F++ + +FC R P + + S A GI P + L + + + + LP+S L S +S S S+ + G+ IQ ++ S K T+ +R S SD +TLY M + S L + S ++ D+ + S+++ +G +I + G + + LA+SD LT P+ +S I + C+ ++SA++ +L V V++F+ HCA NW ++ + WQK + + E+ ++ PG ++T L R + G RN A K + +A + G A + +R+Y +P+ + V E G+RL+ F +E GN+ + I D+ + S + + + + H LHCS F + IN + ++ V YQ S S+ + S + Y A + K + F+LP K +L +LLD +DWR LA+ L R LQFF++ S T +LLDLWEA + S +++ +L+ LR MGR D V +LE+ L
Sbjct: 1 MRKHFLKSPVAQRVQEGTTLQLPCQAPESDPKAELTWYKDGVVV----QPDANVIRASDGSLIMSAARLSDSGNYTCEATNVANSRKTDPVEVQIYVDGGWSEWSPWIGTC------HVDCPLLRQHAHRIRDPHDVLPHQRRTRTCNNPAPLNDGEYCKGEEEMTRSCKVPCKLDGGWSSWSDWSACSSS-CHRYRTRACTVPPPMNGGQPCFG--DDLMTQECPAQLCT----------ADSSRIVISDTAVYGSVASIFIVASFILAILAMFCCKRGNSKKSKPLKPQKMNSEKAGGIYYSEPPGVRRLLLEHQHGTLLGEKISSCSQYFEPPPLPHST-TLRSGKSAFSGYSSTRNAGSRAALIQE-------CSSSSSGSGGKRTM-LRTSSSNCSDDDNYATLYDYM---EDKSVLGLDTSQNIV-----AAQIDSNGARLSLSK-------SGARLIVPELAVEGEKMLYLAVSD-TLTDQPHLKPIESALSPVIVIGQCDV-----SMSAHDNILRRPV------VVSFR-------HCASTFPRDNWQFTLYAD-----EGSGWQKAVTIGEENLNTNMFVQFEQPGKKNDGFGWCHVMTYSLARLMLAGHPRRNSLSAAKRVHLAVF--GPTEMSAYRRPFELRVYCVPETGAAMESVWKQED---GSRLLCESNDFIL-NEKGNLCICIEDVIPGF---SCDGPEVVEISETQHRFVAQNGLHCSLKFRPKEINGSQFSTRVIV-------------YQKAS--------------STEPMVMEVSNEPELYDATSEER--------EKGSVCVEFRLPFGVKDELARLLDMPNESHSDWRGLAKKLHYDRYLQFFASFPDCSPTSLLLDLWEASSSGSARAVPDLLQTLRVMGRPDAVMVLERFL 802
BLAST of Unc-5 netrin receptor B vs. Ensembl Celegans
Match: unc-5 (Netrin receptor unc-5 [Source:UniProtKB/Swiss-Prot;Acc:Q26261]) HSP 1 Score: 135.576 bits (340), Expect = 3.301e-32 Identity = 204/855 (23.86%), Postives = 336/855 (39.30%), Query Frame = 3
Query: 915 LSNIRLTDSGNYSCVASSFGLERHAT-AQILVFEVGQWSDWSEWTGICPNICSKGSNCPKVCSTS-----------RQQRVRYCNQIK--NQKANCIGSEIEYKRCDLICD-PNLWTFWSEWSKCSGNPCKKERTRQCTT---NNCGK---ASSVEIDNCTLAECGGFVASFINSNKKYPESSTSIYITHDVAMYIGLFVAVSVFLMVVAIIFCLIRRRVIGFSPNRVWRY-STTANGIQMFYPDXXXXXXXXXXXXXXXXXXDINQPSLYRSIVLPNSLPFLPSNQSDASSNSAYTDVGNDITYIQRNHLPSLPMIATPLLSSMKPTLKIRPSY---SDSKVSSTLYPQMGLVKHVSTLPIPVSSSLSDHYQELGNTDNETSDQSVTEPCLPYNFNGENMIWATIDSSGGR-ISLALSDINLTCPPN--SFAPGISEPIFLATCNSEQDLPNLSANETLLSPVVVCGPTNVIAFKPFILNIPHCAYNTDSGNWAISVLTSYSPLKQKPYWQKYLDLDAEDKDS-------PPGYAQLAKDRLFLITNQLQRFCVVGSSYRNK-RATKVLRIAAYCTGLDRRHADEQ-IVVRLYLIPDIAECISKVHNFETNRLGARLVTNQKQFFCEDEAGNITVVISDLAMDWQASSANNYQEIPFKDVWH----SPTLHCSFNFIKRLINANSSELKISVNSLDFNWFCTLSIYQTNSHHNKQTVLLSTPNGSSHTSISATSTQFSNYSAGGSQSFPYFVDDCSKTNFESVFKLPEQTKIKLCKLLDSLTPLDNDWRQLARHLSITRSLQFFSN--KLSSTEILLDLWEAQNH-SRKSLNNLIDILRKMGRLDCVAILEKDL 3347
+S RL+DSGNY+C A++ R ++ ++ G WS+WS W G C +CP + + Q+R R CN N C G E + C + C W+ WS+WS CS + C + RTR CT N G+ + C C + + S+ S SI+I V+ F++ + +FC R P + + S A GI P + L + + + + LP+S L S +S S S+ + G+ IQ ++ S K T+ +R S SD +TLY M + S L + S ++ D+ + S+++ +G +I + G + + LA+SD LT P+ +S I + C+ ++SA++ +L +P +++ HCA NW ++ + WQK + + E+ ++ PG ++T L R + G RN A K + +A + G A + +R+Y +P+ + V E G+RL+ F +E GN+ + I D+ + S + + + + H LHCS F + IN + ++ V YQ S S+ + S + Y A + K + F+LP K +L +LLD +DWR LA+ L R LQFF++ S T +LLDLWEA + S +++ +L+ LR MGR D V +LE+ L
Sbjct: 1 MSAARLSDSGNYTCEATNVANSRKTDPVEVQIYVDGGWSEWSPWIGTC------HVDCPLLRQHAHRIRDPHDVLPHQRRTRTCNNPAPLNDGEYCKGEEEMTRSCKVPCKLDGGWSSWSDWSACSSS-CHRYRTRACTVPPPMNGGQPCFGDDLMTQECPAQLCTADSSRIVISDTAVYGSVASIFI-------------VASFILAILAMFCCKRGNSKKSKPLKPQKMNSEKAGGIYYSEPPGVRRLLLEHQHGTLLGEKISSCSQYFEPPPLPHSTT-LRSGKSAFSGYSSTRNAGSRAALIQE-------CSSSSSGSGGKRTM-LRTSSSNCSDDDNYATLYDYM---EDKSVLGLDTSQNIV-----AAQIDSNGARLSLSK-------SGARLIVPELAVEGEKMLYLAVSD-TLTDQPHLKPIESALSPVIVIGQCDV-----SMSAHDNILR-------------RPVVVSFRHCASTFPRDNWQFTLYAD-----EGSGWQKAVTIGEENLNTNMFVQFEQPGKKNDGFGWCHVMTYSLARLMLAGHPRRNSLSAAKRVHLAVF--GPTEMSAYRRPFELRVYCVPETGAAMESVWKQED---GSRLLCESNDFIL-NEKGNLCICIEDVIPGF---SCDGPEVVEISETQHRFVAQNGLHCSLKFRPKEINGSQFSTRVIV-------------YQKAS--------------STEPMVMEVSNEPELYDATSEER--------EKGSVCVEFRLPFGVKDELARLLDMPNESHSDWRGLAKKLHYDRYLQFFASFPDCSPTSLLLDLWEASSSGSARAVPDLLQTLRVMGRPDAVMVLERFL 743
BLAST of Unc-5 netrin receptor B vs. Ensembl Celegans
Match: unc-5 (Netrin receptor unc-5 [Source:UniProtKB/Swiss-Prot;Acc:Q26261]) HSP 1 Score: 123.25 bits (308), Expect = 1.416e-28 Identity = 122/461 (26.46%), Postives = 197/461 (42.73%), Query Frame = 3
Query: 2034 ENMIWATIDSSGGRISLALSDINLTCPPNSFAPGISEPIFLATCNSEQDLPNLSANETLLSPVVVCGPTNV-------IAFKPFILNIPHCAYNTDSGNWAISVLTSYSPLKQKPYWQKYLDLDAEDKDS-------PPGYAQLAKDRLFLITNQLQRFCVVGSSYRNK-RATKVLRIAAYCTGLDRRHADEQ-IVVRLYLIPDIAECISKVHNFETNRLGARLVTNQKQFFCEDEAGNITVVISDLAMDWQASSANNYQEIPFKDVWH----SPTLHCSFNFIKRLINANSSELKISVNSLDFNWFCTLSIYQTNSHHNKQTVLLSTPNGSSHTSISATSTQFSNYSAGGSQSFPYFVDDCSKTNFESVFKLPEQTKIKLCKLLDSLTPLDNDWRQLARHLSITRSLQFFSN--KLSSTEILLDLWEA-QNHSRKSLNNLIDILRKMGRLDCVAILEKDL 3347
+N++ A IDS+G R+SL+ S L P A + ++LA ++ D P+L E+ LSPV+V G +V I +P +++ HCA NW ++ + WQK + + E+ ++ PG ++T L R + G RN A K + +A + G A + +R+Y +P+ + V E G+RL+ F +E GN+ + I D+ + S + + + + H LHCS F + IN + ++ V YQ S S+ + S + Y A + K + F+LP K +L +LLD +DWR LA+ L R LQFF++ S T +LLDLWEA + S +++ +L+ LR MGR D V +LE+ L
Sbjct: 239 QNIVAAQIDSNGARLSLSKSGARLIVP--ELAVEGEKMLYLAVSDTLTDQPHLKPIESALSPVIVIGQCDVSMSAHDNILRRPVVVSFRHCASTFPRDNWQFTLYAD-----EGSGWQKAVTIGEENLNTNMFVQFEQPGKKNDGFGWCHVMTYSLARLMLAGHPRRNSLSAAKRVHLAVF--GPTEMSAYRRPFELRVYCVPETGAAMESVWKQED---GSRLLCESNDFIL-NEKGNLCICIEDVIPGF---SCDGPEVVEISETQHRFVAQNGLHCSLKFRPKEINGSQFSTRVIV-------------YQKAS--------------STEPMVMEVSNEPELYDATSEER--------EKGSVCVEFRLPFGVKDELARLLDMPNESHSDWRGLAKKLHYDRYLQFFASFPDCSPTSLLLDLWEASSSGSARAVPDLLQTLRVMGRPDAVMVLERFL 648
BLAST of Unc-5 netrin receptor B vs. Ensembl Fly
Match: unc-5 (gene:FBgn0034013 transcript:FBtr0339998) HSP 1 Score: 102.834 bits (255), Expect = 1.119e-21 Identity = 97/373 (26.01%), Postives = 147/373 (39.41%), Query Frame = 3
Query: 375 VPKFIQQPKSMYYVSKSHPAVITCIA--------------QPVSHVNIFCADKQYSYMNEEVSATGLKVIKMDNEGRLAVKGNRWKFSLEVQHKDVIEWF---SEYRCHCEAWNQIEQLQKVKKVESSSAVIYDSYINKDFKTVPKNQKVSVRGSVKLSCIPPDAKPPAEIHWVKNGEKITGKSHPQFEINEYGELLLSNIRLTDSGNYSCVASSFGLERHATAQILVFEV-GQWSDWSEWTGICPNICSKGSNCPKVCSTSRQQRVRYCNQIK--NQKANCIGSEIEYKRCDLICDPN-------------------LWTFWSEWSKCSGNPCKKERTRQCTTNNCGKASS--VEIDNCTLAECGGFVASFI 1370
+P F+ +P+S++ V K+ PAV+ C A QP + D EEV+AT H+D+++ F ++C C AW+ V+S +A ++ +YI K F P + ++ + +L C PP P ++ W KN IT S P ++ G L+ + L NYSC A + R + + +L+ V G WS WS W + C S R +R R CN N A C G +I+ K D P W+ WS+WS CS C + R R+C T + SS E + L G +A+ I
Sbjct: 127 LPIFLIEPESVFVV-KNRPAVLKCKASHSLQVIFKCSGSSQPPPSTHETHVDPHTGVNMEEVTAT--------------------------IHRDLVDEFFGDGPFKCECHAWS------SRGVVKSQAATVHIAYIRKSFNQSPTSLRLELGSRAELRCEPPGGFPEPKLTWHKNNAVITADSEPGITVSA-GTLIFRQVALQHMANYSCSAENIAGRRVSDSAVLIVYVNGGWSTWSPW---------RECKCAGKPSQGR-KRSRTCNNPMPLNGGAQCPGPQIQ-KSADCAACPEDTQIVSPDGFDISSSKRMARWSAWSDWSICSAE-CIQVRRRKCLTQGQTQISSEAEEAGDLLLGAPGVGMAALI 453 HSP 2 Score: 95.5153 bits (236), Expect = 2.000e-19 Identity = 106/490 (21.63%), Postives = 208/490 (42.45%), Query Frame = 3
Query: 1926 PVSSSLSDHYQELGNTDNETSDQSVTEPCLPYNFNGENMI--------WATIDSSGGRISLALSDINLTCPPNSFAPGISEPIFLATCNSEQDLPNLSANETLL-SPVVVCGPTNVIAFKPFILNIPHCAYNTDSGNWAISVLTSYSPLKQKPY-WQKYLDLDAEDKDSPPGYAQLAKDRLFLITNQLQRFCVVGSSYRNKRATKVLRIAAYCTGLDRRHADEQIVVRLYLIPDIAECISKVHNFETNRLGARLVTNQKQFFCEDEAGNITVVISDLAMDWQASSANNYQEIPFKDVW-HSPTLHCSFNFIKRLINANSSELKISVNSLDFNWFCTLSIYQTNSHHNKQTVLLSTPNGSSHTSISATSTQFSNYSAGGSQSFPYFVDDCSKTNFESVFKLPEQTKIKLCKLLDSLTPLDNDWRQLARHLSITRSLQFFSNKLSSTEILLDLWEAQNH---------SRKSLNNLIDILRKMGRLDCVAIL 3335
P+ D+ E G + + S ++ NG+ I + + S+GG++ L ++ L P ++ + + + L + E + + ++L S VV P N KP IL IPHC + W + + + S + W++ + + E+ + P + QL +F++T QL F VV R ++ + +++ A+ +A+ +R+Y++ D N E +LG + + F + N+ + + + D +A++ + IP++ + ++ LHC F+ ++ D N C + + + + +GS+ S T+T S G +V++ +F +LP TK +C LD + DWR LA+ L+ R + +F+ K S TE +L+LWE + + ++ L+ L++MGR D + I+
Sbjct: 615 PIDHLSVDYLSETGESSTADTSNST------FDMNGKLSILNASKSSTYEMLGSAGGQLRLYGGELLLFVPEHAIGKHVKKHVSLLLLSDECSRVSCATESSILCSSVVHSAPRNYSFVKPVILKIPHCLVAPE--QWHVHIYHADSEHDELSVNWRRAVSV-GEETINTPMFVQLEATHVFIMTEQLGHFTVVAEP-RIQQPSIKMKLLAFSQHTPPSNAN--CSLRIYVVKDFPNSRDICANVEA-KLGGSFLGESQVFAFTLNSRNLNIRVR--SADVEAAAPYEHA-IPYQHILSNNSILHCEFSLRRQ----------------DQNSLCVDFGQGSEDDYYTFNIPAHSMSGSAEELASTTNTTISIDRQGN------YVNESCVMDF---VQLPHATKRLICGALDPPRADERDWRLLAKKLNTDRYIAYFATKASPTEQILNLWECRANSSPGSSSNSVSHTIMALLLTLKEMGRQDVLDII 1063
BLAST of Unc-5 netrin receptor B vs. Ensembl Fly
Match: unc-5 (gene:FBgn0034013 transcript:FBtr0087382) HSP 1 Score: 102.834 bits (255), Expect = 1.119e-21 Identity = 97/373 (26.01%), Postives = 147/373 (39.41%), Query Frame = 3
Query: 375 VPKFIQQPKSMYYVSKSHPAVITCIA--------------QPVSHVNIFCADKQYSYMNEEVSATGLKVIKMDNEGRLAVKGNRWKFSLEVQHKDVIEWF---SEYRCHCEAWNQIEQLQKVKKVESSSAVIYDSYINKDFKTVPKNQKVSVRGSVKLSCIPPDAKPPAEIHWVKNGEKITGKSHPQFEINEYGELLLSNIRLTDSGNYSCVASSFGLERHATAQILVFEV-GQWSDWSEWTGICPNICSKGSNCPKVCSTSRQQRVRYCNQIK--NQKANCIGSEIEYKRCDLICDPN-------------------LWTFWSEWSKCSGNPCKKERTRQCTTNNCGKASS--VEIDNCTLAECGGFVASFI 1370
+P F+ +P+S++ V K+ PAV+ C A QP + D EEV+AT H+D+++ F ++C C AW+ V+S +A ++ +YI K F P + ++ + +L C PP P ++ W KN IT S P ++ G L+ + L NYSC A + R + + +L+ V G WS WS W + C S R +R R CN N A C G +I+ K D P W+ WS+WS CS C + R R+C T + SS E + L G +A+ I
Sbjct: 127 LPIFLIEPESVFVV-KNRPAVLKCKASHSLQVIFKCSGSSQPPPSTHETHVDPHTGVNMEEVTAT--------------------------IHRDLVDEFFGDGPFKCECHAWS------SRGVVKSQAATVHIAYIRKSFNQSPTSLRLELGSRAELRCEPPGGFPEPKLTWHKNNAVITADSEPGITVSA-GTLIFRQVALQHMANYSCSAENIAGRRVSDSAVLIVYVNGGWSTWSPW---------RECKCAGKPSQGR-KRSRTCNNPMPLNGGAQCPGPQIQ-KSADCAACPEDTQIVSPDGFDISSSKRMARWSAWSDWSICSAE-CIQVRRRKCLTQGQTQISSEAEEAGDLLLGAPGVGMAALI 453 HSP 2 Score: 95.5153 bits (236), Expect = 2.000e-19 Identity = 106/490 (21.63%), Postives = 208/490 (42.45%), Query Frame = 3
Query: 1926 PVSSSLSDHYQELGNTDNETSDQSVTEPCLPYNFNGENMI--------WATIDSSGGRISLALSDINLTCPPNSFAPGISEPIFLATCNSEQDLPNLSANETLL-SPVVVCGPTNVIAFKPFILNIPHCAYNTDSGNWAISVLTSYSPLKQKPY-WQKYLDLDAEDKDSPPGYAQLAKDRLFLITNQLQRFCVVGSSYRNKRATKVLRIAAYCTGLDRRHADEQIVVRLYLIPDIAECISKVHNFETNRLGARLVTNQKQFFCEDEAGNITVVISDLAMDWQASSANNYQEIPFKDVW-HSPTLHCSFNFIKRLINANSSELKISVNSLDFNWFCTLSIYQTNSHHNKQTVLLSTPNGSSHTSISATSTQFSNYSAGGSQSFPYFVDDCSKTNFESVFKLPEQTKIKLCKLLDSLTPLDNDWRQLARHLSITRSLQFFSNKLSSTEILLDLWEAQNH---------SRKSLNNLIDILRKMGRLDCVAIL 3335
P+ D+ E G + + S ++ NG+ I + + S+GG++ L ++ L P ++ + + + L + E + + ++L S VV P N KP IL IPHC + W + + + S + W++ + + E+ + P + QL +F++T QL F VV R ++ + +++ A+ +A+ +R+Y++ D N E +LG + + F + N+ + + + D +A++ + IP++ + ++ LHC F+ ++ D N C + + + + +GS+ S T+T S G +V++ +F +LP TK +C LD + DWR LA+ L+ R + +F+ K S TE +L+LWE + + ++ L+ L++MGR D + I+
Sbjct: 615 PIDHLSVDYLSETGESSTADTSNST------FDMNGKLSILNASKSSTYEMLGSAGGQLRLYGGELLLFVPEHAIGKHVKKHVSLLLLSDECSRVSCATESSILCSSVVHSAPRNYSFVKPVILKIPHCLVAPE--QWHVHIYHADSEHDELSVNWRRAVSV-GEETINTPMFVQLEATHVFIMTEQLGHFTVVAEP-RIQQPSIKMKLLAFSQHTPPSNAN--CSLRIYVVKDFPNSRDICANVEA-KLGGSFLGESQVFAFTLNSRNLNIRVR--SADVEAAAPYEHA-IPYQHILSNNSILHCEFSLRRQ----------------DQNSLCVDFGQGSEDDYYTFNIPAHSMSGSAEELASTTNTTISIDRQGN------YVNESCVMDF---VQLPHATKRLICGALDPPRADERDWRLLAKKLNTDRYIAYFATKASPTEQILNLWECRANSSPGSSSNSVSHTIMALLLTLKEMGRQDVLDII 1063
BLAST of Unc-5 netrin receptor B vs. Ensembl Fly
Match: pyd (gene:FBgn0262614 transcript:FBtr0310205) HSP 1 Score: 58.5362 bits (140), Expect = 4.217e-8 Identity = 31/99 (31.31%), Postives = 48/99 (48.48%), Query Frame = 3
Query: 2055 IDSSGGRISLALSDINLTCPPNSFAPGISEPIFLATCNSEQDLP------NLSANETLLSPVVVCGPTNVIAFKPFILNIPHCAYNTDSGNWAISVLTS 2333
DS+GG ++ L ++L PP + G+ + I+ + ++ ET+LSP+V+CGP + P LNIPHCA T S A+ S
Sbjct: 2268 FDSNGGTLADKLWHVSLQIPPGAIPAGVRQEIYFTVSDPRMGQAVGGPPLDMENGETMLSPLVMCGPQGLEFLVPVTLNIPHCAGRTASLGLALKATDS 2366
BLAST of Unc-5 netrin receptor B vs. Ensembl Fly
Match: pyd (gene:FBgn0262614 transcript:FBtr0305297) HSP 1 Score: 58.5362 bits (140), Expect = 4.554e-8 Identity = 31/99 (31.31%), Postives = 48/99 (48.48%), Query Frame = 3
Query: 2055 IDSSGGRISLALSDINLTCPPNSFAPGISEPIFLATCNSEQDLP------NLSANETLLSPVVVCGPTNVIAFKPFILNIPHCAYNTDSGNWAISVLTS 2333
DS+GG ++ L ++L PP + G+ + I+ + ++ ET+LSP+V+CGP + P LNIPHCA T S A+ S
Sbjct: 1963 FDSNGGTLADKLWHVSLQIPPGAIPAGVRQEIYFTVSDPRMGQAVGGPPLDMENGETMLSPLVMCGPQGLEFLVPVTLNIPHCAGRTASLGLALKATDS 2061
BLAST of Unc-5 netrin receptor B vs. Ensembl Fly
Match: robo1 (gene:FBgn0005631 transcript:FBtr0071922) HSP 1 Score: 54.299 bits (129), Expect = 7.077e-7 Identity = 55/231 (23.81%), Postives = 97/231 (41.99%), Query Frame = 3
Query: 348 LPSEKHLEGVPKFIQQPKSMYYVSKSHPAVITCI--AQPVSHVNIFCADKQYSYMNEEVSATGLKVIKMDNEGRLAVKGNRWKFSLEVQHKDVIEWFSEYRCHCEAWNQIEQLQKVKKVESSSAVIYDSYINKDFKTVPKNQKVSVRGSVKLSCIPPDAKPPAEIHWVKNG------EKITGKSHPQFEINEYGELLLSNIRLTDSGNYSCVASSFGLERHATAQILVFEV 1016
LP+ + P+ I+ P + V K+ PA + C +P + F D + NE+ S R+ K F +Q K + EY C + +V + S A + + + DF+ PK+ +V+ + L C PP P + W+K+G + ++ + + I + G LL+SN+ D GNY C+A + R ++ L+ +V
Sbjct: 46 LPAVRGQYQSPRIIEHPTDLV-VKKNEPATLNCKVEGKPEPTIEWF-KDGEPVSTNEKKSH------------RVQFKDGALFFYRTMQGKKEQDG-GEYWCVAK--------NRVGQAVSRHASLQIAVLRDDFRVEPKDTRVAKGETALLECGPPKGIPEPTLIWIKDGVPLDDLKAMSFGASSRVRIVDGGNLLISNVEPIDEGNYKCIAQNLVGTRESSYAKLIVQV 253
BLAST of Unc-5 netrin receptor B vs. Ensembl Zebrafish
Match: unc5b (unc-5 netrin receptor B [Source:ZFIN;Acc:ZDB-GENE-041213-1]) HSP 1 Score: 288.886 bits (738), Expect = 3.970e-82 Identity = 275/1023 (26.88%), Postives = 439/1023 (42.91%), Query Frame = 3
Query: 369 EGVPKFIQQPKSMYYVSKSHPAVITCIAQPVSHVNIFCADKQYSYMNEEVSATGLKVIKMDNEGRLAVKGNRWKFSLEVQHKDVIEWFS--EYRCHCEAWNQIEQLQKVKKVESSSAVIYDSYINKDFKTVPKNQKVSVRGSVKLSCIPPDAKPPAEIHWVKNGEKITGKSHPQFEINEYGELLLSNIRLTDSGNYSCVASSF-GLERHATAQILVFEVGQWSDWSEWTGICPNICSKGSNCPKVCSTSRQQRVRYCNQIK--NQKANCIGSEIEYKRCDLICDPNL-WTFWSEWSKCSGNPCKKERTRQCTT---NNCGK---ASSVEIDNCTLAECGGFVASFINSNKKYPESSTS--IYITHDVAMYIGLFVAVSVFLMVVAIIFCLIRRRVIGFSPNRVWRYSTTANGIQMFYPDXXXXXXXXXXXXXXXXXXDINQPSLYRSIVLPNSLPFLPSNQSDASSNSAYTDVGNDITYIQRNHLPS---LPMIATPLLSSMKPTLKIRPSYSDSKVSSTLYPQ-MGLVKHVSTLPIPVSSSLSDHYQELGNTDNETSDQSVTEPCLPYNFNGENMIWATIDSSGGRISLALSDINLTCPPNSFAPGISEPIFLATCNSEQDLPNLSANETLLSPVVVCGPTNVIAFKPFILNIPHCAYNTDSGNWAISVLTSYSPLKQKPYWQKYLDLDAEDKDSPPGYAQLAKDRLFLITNQLQRFCVVGSSYRNKRATKVLRIAAY-----CTGLDRRHADEQIVVRLYLIPDIAECISKVHNFETNRLGARLVTNQKQFFCEDEAGNITVVISDLAMD-WQASSANNYQEIPFKDVWHSPT--LHCSFNFIKRLINANSSELKISVNSLDFNWFCTLSIYQTNSHHNKQTVLLSTPNGSSHTSISATSTQFSNYSAGGS-----QSFPYFVDDCSKTNFESVFKLPEQTKIKLCKLLDSLTPLDNDWRQLARHLSITRSLQFFSNKLSSTEILLDLWEAQNHSRKSLNNLIDILRKMGRLDCVAILEKD 3344
E +P+F +P+ + V K+ P ++C A P + + C + ++ N+ V+ L D+ L V+ + + V V E F +Y C C AW+ +S A + +Y+ K+F+ P ++V + V L C PP+ PPAE+ W+KN E I F I +L++ RL+D+ NY+CVA + R +TA ++V+ G WS W+EW S C C Q+R R C N A C G + C +C + WT W++WS C G C R+R+C N G+ S +E NCT C NKK TS + VA+Y GL A+ + +++V + L+ RR + S+ F+P Y+ N P+ D ++ SA T G + +Q+ L S +PM +PLL + P+LKI+ Y+ S +SS P +G V V S DH+ G+T S + AT+ S GGR+++ + ++L PP + G ++L E+ ++T+LSPVV CGP+ ++ +P +L +PHCA + +W +++ + W++ L + E+ S P Y Q+ + ++ QL + +VG S + A K L++A + C LD +R+Y I D + +V E + LG L+ + K +D N+ + I D+ W++ YQEIPF +W LHC+F+ + + + KI V ++ I+Q N T I T S AGGS Q PY F+LP + K+C LD+ + DWR LAR L+ R L +F+ K S T +LLDLWEA + L +L L +MG+ + + ++ D
Sbjct: 19 EPLPEFQSEPEDAFIV-KNRPVKLSCKAAPATQIYFKC-NGEWVNQNDHVTKESL-----DHITGLVVR----EVDISVSRTQVEELFGLEDYWCQCVAWS------SAGTTKSRRAYVRIAYLRKNFEQEPLGREVRLEQEVLLQCRPPEGSPPAEVDWLKNEELIDPALDSNFLITIEHDLIIKQARLSDTANYTCVARNVVAKRRSSTATLIVYVSGGWSSWTEW-----------SECNAQCGRGWQRRTRSCTNPAPLNGGAFCDGPPFQRVTCTTLCPVDGGWTEWAKWSAC-GTECTHWRSRECQAPPPRNGGRHCSGSMMESKNCTEGLCA--------RNKKVSVEHTSHPLGSGTGVAVYAGLVGALLLCVILVLCVGILVYRRSCRHLHGEITDSSSALTA--AFHPGN------------------------YKPPRQDNPHLLHPTAPPDLTA-SAGTFRG-PLFSLQQATLDSHHKIPMTTSPLLDPL-PSLKIK-VYNSSTMSSLELPTGLGSVDGDIMSLKTVGSGPKDHH---GHTLPREPSHSAS---------------ATLGSLGGRLTIPNTGVSLLVPPGTIPQGKFYEMYLIINKWEKTTLPSDGSQTVLSPVVSCGPSGMLLSRPVVLTLPHCA-QLEPPDWTLTLKMQ----NHQGAWEEVLTV-GEESLSSPCYLQVEEQSCHILMEQLGTYGLVGQSAPPRPACKRLQLALFAPRAPCLSLD-------YSLRVYCIQDTPHALKEVLEVERS-LGGVLLEDPKPLLFKDSYHNMRLSIHDIPHSHWRSKLLAKYQEIPFYHIWSGSQRPLHCTFSLERGSLVVSQLTCKICVRQVEGEG----QIFQLN------------------TDIQETLPPHSPLPAGGSCLPSSQVGPY------------AFRLPVSIRQKICASLDAPSARGCDWRMLARSLAFDRYLNYFATKPSPTGVLLDLWEACHQGDADLVSLATALEEMGKSEVLVVMTTD 908
BLAST of Unc-5 netrin receptor B vs. Ensembl Zebrafish
Match: unc5b (unc-5 netrin receptor B [Source:ZFIN;Acc:ZDB-GENE-041213-1]) HSP 1 Score: 289.656 bits (740), Expect = 4.043e-82 Identity = 275/1023 (26.88%), Postives = 439/1023 (42.91%), Query Frame = 3
Query: 369 EGVPKFIQQPKSMYYVSKSHPAVITCIAQPVSHVNIFCADKQYSYMNEEVSATGLKVIKMDNEGRLAVKGNRWKFSLEVQHKDVIEWFS--EYRCHCEAWNQIEQLQKVKKVESSSAVIYDSYINKDFKTVPKNQKVSVRGSVKLSCIPPDAKPPAEIHWVKNGEKITGKSHPQFEINEYGELLLSNIRLTDSGNYSCVASSF-GLERHATAQILVFEVGQWSDWSEWTGICPNICSKGSNCPKVCSTSRQQRVRYCNQIK--NQKANCIGSEIEYKRCDLICDPNL-WTFWSEWSKCSGNPCKKERTRQCTT---NNCGK---ASSVEIDNCTLAECGGFVASFINSNKKYPESSTS--IYITHDVAMYIGLFVAVSVFLMVVAIIFCLIRRRVIGFSPNRVWRYSTTANGIQMFYPDXXXXXXXXXXXXXXXXXXDINQPSLYRSIVLPNSLPFLPSNQSDASSNSAYTDVGNDITYIQRNHLPS---LPMIATPLLSSMKPTLKIRPSYSDSKVSSTLYPQ-MGLVKHVSTLPIPVSSSLSDHYQELGNTDNETSDQSVTEPCLPYNFNGENMIWATIDSSGGRISLALSDINLTCPPNSFAPGISEPIFLATCNSEQDLPNLSANETLLSPVVVCGPTNVIAFKPFILNIPHCAYNTDSGNWAISVLTSYSPLKQKPYWQKYLDLDAEDKDSPPGYAQLAKDRLFLITNQLQRFCVVGSSYRNKRATKVLRIAAY-----CTGLDRRHADEQIVVRLYLIPDIAECISKVHNFETNRLGARLVTNQKQFFCEDEAGNITVVISDLAMD-WQASSANNYQEIPFKDVWHSPT--LHCSFNFIKRLINANSSELKISVNSLDFNWFCTLSIYQTNSHHNKQTVLLSTPNGSSHTSISATSTQFSNYSAGGS-----QSFPYFVDDCSKTNFESVFKLPEQTKIKLCKLLDSLTPLDNDWRQLARHLSITRSLQFFSNKLSSTEILLDLWEAQNHSRKSLNNLIDILRKMGRLDCVAILEKD 3344
E +P+F +P+ + V K+ P ++C A P + + C + ++ N+ V+ L D+ L V+ + + V V E F +Y C C AW+ +S A + +Y+ K+F+ P ++V + V L C PP+ PPAE+ W+KN E I F I +L++ RL+D+ NY+CVA + R +TA ++V+ G WS W+EW S C C Q+R R C N A C G + C +C + WT W++WS C G C R+R+C N G+ S +E NCT C NKK TS + VA+Y GL A+ + +++V + L+ RR + S+ F+P Y+ N P+ D ++ SA T G + +Q+ L S +PM +PLL + P+LKI+ Y+ S +SS P +G V V S DH+ G+T S + AT+ S GGR+++ + ++L PP + G ++L E+ ++T+LSPVV CGP+ ++ +P +L +PHCA + +W +++ + W++ L + E+ S P Y Q+ + ++ QL + +VG S + A K L++A + C LD +R+Y I D + +V E + LG L+ + K +D N+ + I D+ W++ YQEIPF +W LHC+F+ + + + KI V ++ I+Q N T I T S AGGS Q PY F+LP + K+C LD+ + DWR LAR L+ R L +F+ K S T +LLDLWEA + L +L L +MG+ + + ++ D
Sbjct: 48 EPLPEFQSEPEDAFIV-KNRPVKLSCKAAPATQIYFKC-NGEWVNQNDHVTKESL-----DHITGLVVR----EVDISVSRTQVEELFGLEDYWCQCVAWS------SAGTTKSRRAYVRIAYLRKNFEQEPLGREVRLEQEVLLQCRPPEGSPPAEVDWLKNEELIDPALDSNFLITIEHDLIIKQARLSDTANYTCVARNVVAKRRSSTATLIVYVSGGWSSWTEW-----------SECNAQCGRGWQRRTRSCTNPAPLNGGAFCDGPPFQRVTCTTLCPVDGGWTEWAKWSAC-GTECTHWRSRECQAPPPRNGGRHCSGSMMESKNCTEGLCA--------RNKKVSVEHTSHPLGSGTGVAVYAGLVGALLLCVILVLCVGILVYRRSCRHLHGEITDSSSALTA--AFHPGN------------------------YKPPRQDNPHLLHPTAPPDLTA-SAGTFRG-PLFSLQQATLDSHHKIPMTTSPLLDPL-PSLKIK-VYNSSTMSSLELPTGLGSVDGDIMSLKTVGSGPKDHH---GHTLPREPSHSAS---------------ATLGSLGGRLTIPNTGVSLLVPPGTIPQGKFYEMYLIINKWEKTTLPSDGSQTVLSPVVSCGPSGMLLSRPVVLTLPHCA-QLEPPDWTLTLKMQ----NHQGAWEEVLTV-GEESLSSPCYLQVEEQSCHILMEQLGTYGLVGQSAPPRPACKRLQLALFAPRAPCLSLD-------YSLRVYCIQDTPHALKEVLEVERS-LGGVLLEDPKPLLFKDSYHNMRLSIHDIPHSHWRSKLLAKYQEIPFYHIWSGSQRPLHCTFSLERGSLVVSQLTCKICVRQVEGEG----QIFQLN------------------TDIQETLPPHSPLPAGGSCLPSSQVGPY------------AFRLPVSIRQKICASLDAPSARGCDWRMLARSLAFDRYLNYFATKPSPTGVLLDLWEACHQGDADLVSLATALEEMGKSEVLVVMTTD 937
BLAST of Unc-5 netrin receptor B vs. Ensembl Zebrafish
Match: unc5b (unc-5 netrin receptor B [Source:ZFIN;Acc:ZDB-GENE-041213-1]) HSP 1 Score: 287.345 bits (734), Expect = 2.372e-81 Identity = 271/1021 (26.54%), Postives = 435/1021 (42.61%), Query Frame = 3
Query: 369 EGVPKFIQQPKSMYYVSKSHPAVITCIAQPVSHVNIFCADKQYSYMNEEVSATGLKVIKMDNEGRLAVKGNRWKFSLEVQHKDVIEWFS--EYRCHCEAWNQIEQLQKVKKVESSSAVIYDSYINKDFKTVPKNQKVSVRGSVKLSCIPPDAKPPAEIHWVKNGEKITGKSHPQFEINEYGELLLSNIRLTDSGNYSCVASSF-GLERHATAQILVFEVGQWSDWSEWTGICPNICSKGSNCPKVCSTSRQQRVRYCNQIK--NQKANCIGSEIEYKRCDLICDPNL-WTFWSEWSKCSGNPCKKERTRQCTT---NNCGK---ASSVEIDNCTLAECGGFVASFINSNKKYPESSTSIYITHDVAMYIGLFVAVSVFLMVVAIIFCLIRRRVIGFSPNRVWRYSTTANGIQMFYPDXXXXXXXXXXXXXXXXXXDINQPSLYRSIVLPNSLPFLPSNQSDASSNSAYTDVGNDITYIQRNHLPS---LPMIATPLLSSMKPTLKIRPSYSDSKVSSTLYPQ-MGLVKHVSTLPIPVSSSLSDHYQELGNTDNETSDQSVTEPCLPYNFNGENMIWATIDSSGGRISLALSDINLTCPPNSFAPGISEPIFLATCNSEQDLPNLSANETLLSPVVVCGPTNVIAFKPFILNIPHCAYNTDSGNWAISVLTSYSPLKQKPYWQKYLDLDAEDKDSPPGYAQLAKDRLFLITNQLQRFCVVGSSYRNKRATKVLRIAAY-----CTGLDRRHADEQIVVRLYLIPDIAECISKVHNFETNRLGARLVTNQKQFFCEDEAGNITVVISDLAMD-WQASSANNYQEIPFKDVWHSPT--LHCSFNFIKRLINANSSELKISVNSLDFNWFCTLSIYQTNSHHNKQTVLLSTPNGSSHTSISATSTQFSNYSAGGS-----QSFPYFVDDCSKTNFESVFKLPEQTKIKLCKLLDSLTPLDNDWRQLARHLSITRSLQFFSNKLSSTEILLDLWEAQNHSRKSLNNLIDILRKMGRLDCVAILEKD 3344
E +P+F +P+ + V K+ P ++C A P + + C + ++ N+ V+ L D+ L V+ + + V V E F +Y C C AW+ +S A + +Y+ K+F+ P ++V + V L C PP+ PPAE+ W+KN E I F I +L++ RL+D+ NY+CVA + R +TA ++V+ G WS W+EW S C C Q+R R C N A C G + C +C + WT W++WS C G C R+R+C N G+ S +E NCT C + S VA+Y GL A+ + +++V + L+ RR + S+ F+P Y+ N P+ D ++ SA T G + +Q+ L S +PM +PLL + P+LKI+ Y+ S +SS P +G V V S DH+ G+T S + AT+ S GGR+++ + ++L PP + G ++L E+ ++T+LSPVV CGP+ ++ +P +L +PHCA + +W +++ + W++ L + E+ S P Y Q+ + ++ QL + +VG S + A K L++A + C LD +R+Y I D + +V E + LG L+ + K +D N+ + I D+ W++ YQEIPF +W LHC+F+ + + + KI V ++ I+Q N T I T S AGGS Q PY F+LP + K+C LD+ + DWR LAR L+ R L +F+ K S T +LLDLWEA + L +L L +MG+ + + ++ D
Sbjct: 48 EPLPEFQSEPEDAFIV-KNRPVKLSCKAAPATQIYFKC-NGEWVNQNDHVTKESL-----DHITGLVVR----EVDISVSRTQVEELFGLEDYWCQCVAWS------SAGTTKSRRAYVRIAYLRKNFEQEPLGREVRLEQEVLLQCRPPEGSPPAEVDWLKNEELIDPALDSNFLITIEHDLIIKQARLSDTANYTCVARNVVAKRRSSTATLIVYVSGGWSSWTEW-----------SECNAQCGRGWQRRTRSCTNPAPLNGGAFCDGPPFQRVTCTTLCPVDGGWTEWAKWSAC-GTECTHWRSRECQAPPPRNGGRHCSGSMMESKNCTEGLCARTLGSGTG-----------------VAVYAGLVGALLLCVILVLCVGILVYRRSCRHLHGEITDSSSALTA--AFHPGN------------------------YKPPRQDNPHLLHPTAPPDLTA-SAGTFRG-PLFSLQQATLDSHHKIPMTTSPLLDPL-PSLKIK-VYNSSTMSSLELPTGLGSVDGDIMSLKTVGSGPKDHH---GHTLPREPSHSAS---------------ATLGSLGGRLTIPNTGVSLLVPPGTIPQGKFYEMYLIINKWEKTTLPSDGSQTVLSPVVSCGPSGMLLSRPVVLTLPHCA-QLEPPDWTLTLKMQ----NHQGAWEEVLTV-GEESLSSPCYLQVEEQSCHILMEQLGTYGLVGQSAPPRPACKRLQLALFAPRAPCLSLD-------YSLRVYCIQDTPHALKEVLEVERS-LGGVLLEDPKPLLFKDSYHNMRLSIHDIPHSHWRSKLLAKYQEIPFYHIWSGSQRPLHCTFSLERGSLVVSQLTCKICVRQVEGEG----QIFQLN------------------TDIQETLPPHSPLPAGGSCLPSSQVGPY------------AFRLPVSIRQKICASLDAPSARGCDWRMLARSLAFDRYLNYFATKPSPTGVLLDLWEACHQGDADLVSLATALEEMGKSEVLVVMTTD 926
BLAST of Unc-5 netrin receptor B vs. Ensembl Zebrafish
Match: unc5da (unc-5 netrin receptor Da [Source:ZFIN;Acc:ZDB-GENE-080908-2]) HSP 1 Score: 248.825 bits (634), Expect = 6.012e-68 Identity = 253/1017 (24.88%), Postives = 426/1017 (41.89%), Query Frame = 3
Query: 375 VPKFIQQPKSMYYVSKSHPAVITCIAQPVSHVNIFCADKQYSYMNEEVS------ATGLKVIKMDNEGRLAVKGNRWKFSLEVQHKDVIEWFSEYRCHCEAWNQIEQLQKVKKVESSSAVIYDSYINKDFKTVPKNQKVSVRGSVKLSCIPPDAKPPAEIHWVKNGEKITGKSHPQFEINEYGELLLSNIRLTDSGNYSCVASSF-GLERHATAQILVFEVGQWSDWSEWTGICPNICSKGSNCPKVCSTSRQQRVRYCNQIK--NQKANCIGSEIEYKRCDLICDPN-LWTFWSEWSKCSGNPCKKERTRQCTT---NNCGK---ASSVEIDNCTLAECGGFVASFINSNKKYPESSTSIYITHDVAMYIGLFVAVSVFLMVVAIIFCLIRRRVIGFSPNRVWRYSTTANGIQMFYPDXXXXXXXXXXXXXXXXXXDINQPSLYRSIVLPNSLPFLPSNQSDASSNSAYTDVGNDITYIQRNHLPSLPMIATPLLSSMKPTLKIRPSYSDSKVSSTLYPQMGLVKHVS--------TLPIPVSSSLSDHYQELGNTDNETSDQSVTEPCLPYNF-NGENMIW--ATIDSSGGRISLALSDINLTCPPNSFAPGISEPIFLATCNSEQDLPNLS--ANETLLSPVVVCGPTNVIAFKPFILNIPHCAYNTDSGNWAISVLTSYSPLKQKPYWQKYLDLDAEDKDSPPGYAQLAKDRLFLITNQLQRFCVVGSSYRNKRATKVLRIAAYCTGLDRRHADEQIVVRLYLIPDIAECISKVHNFETNRLGARLVTNQKQFFCEDEAGNITVVISDL-AMDWQASSANNYQEIPFKDVW---HSPTLHCSFNFIKRLINANSSELKISVNSLDFNWFCTLSIYQTNSHHNKQTVLLSTPNGSSHTSISATSTQFSNYSAGGSQSFPYFVD-DCSKTN--FESVFKLPEQTKIKLCKLLDSLTPLDNDWRQLARHLSITRSLQFFSNKLSSTEILLDLWEAQNHSRKSLNNLIDILRKMGRL 3317
+P F+Q+P Y V KS+P + C A+P + C + ++ + N+ S TGLK+ ++ ++ Q + +Y C C AW+ + +S A + +Y+ K+F+ P+ +V + G + L C PP+ P AE+ W+KN E + + L+++ RL+DSGNY+C+AS+ R ATA ++VF G WS W++W S C C Q+R R C N A C G ++ C C + W+ W+ WS+C+ + C+++RTR+CT + G+ ++++ DNCT C + + K P++ + ++DVA+Y GL A V MVV +I + RR V S G Q F ++S N L S Q D + + YT +++ +P P + PL P LK+ KV S+ +G+ + T P V + S + +P L + NG+ + GGR+ + + ++L P + + ++++ ++QD LS A E LLSP V GP + P L + HCA + +S +W I + Q W++ + L+ E S Y L L+ + + +VG + ++ A K LR+AA+ ++ + I R+Y + D +V + E R G RL+ K + ++ V I D+ W QE F VW SP L C+F+ + AN KISV + + L +Y T + K TV P+F DC+ T+ FK+P+ + ++C D+ DW+ LA+ L I R+L +F+ + S + ++L LWEAQ+ + L++L L ++G++
Sbjct: 43 LPHFLQEPDDAYIV-KSNPIKLRCRARPALQIFFKC-NGEWVHQNQHTSLEHIELGTGLKIREV-------------MINVSRQQVEDFHGPEDYWCLCVAWSHL------GTAKSRKATVRIAYLRKNFEQEPQGMEVPINGMIVLHCRPPEGVPAAEVEWLKNEELVHSLEDINIDTRADHNLIINEARLSDSGNYTCLASNIVARRRSATAMVIVFVNGGWSSWTDW-----------SECNVRCGRGVQKRTRTCTNPAPLNGGAFCEGMSVQKSTCTSPCPVDGGWSEWTMWSECT-SECERQRTRECTDPEPKHGGRLCDGAALDTDNCTGDLC--IQDRKLLHDVKVPQA--DVESSNDVALYSGL--AAGVVTMVVLVIAVTLYRRNQSEYGVDVIDSSALTGGFQSFS---------------------------FKSARQGNPLLMNSSMQPDLTVSRTYTSPICFPDSMEKELIPE-PALFDPL-----PDLKV-------KVHSSFMVSLGVSERAEYHAKAPSQTFPRGVVQEIGGGGGT--LGGRGKSQLTSIQPALISSMTNGKRALRTSGVFGHGGGRLVVPNAGVSLLVPHGAIEEDTTWELYMSI--TQQDSSALSDEAQEILLSPEVTYGPPGLSLSCPVALTVAHCA-DVNSEDWNIKLKRQ----TQDNSWEEVMILEEE---STSCYCLLDTQCCHLLVERPGCYALVGEAL-SQAAGKRLRLAAF-GNMEPNFLNYSI--RVYCVDDTPHAFQEVVSVERGR-GGRLLEEPKTLLFRANSFSLQVSIQDIPQFLWSIKPFTTCQEFSFSQVWCSSQSP-LQCAFSLERYSPAANQLSCKISVRQVKGHEQ-ILQVYTTIAESEKDTV-------------------------------PFFTQSDCTITSQTGSRAFKIPQSIRQRICATFDTANAKGKDWQLLAQKLHIDRNLGYFARQTSPSAVILSLWEAQHQEQGDLDSLASALEEIGKV 930
BLAST of Unc-5 netrin receptor B vs. Ensembl Zebrafish
Match: unc5a (unc-5 netrin receptor A [Source:ZFIN;Acc:ZDB-GENE-080219-19]) HSP 1 Score: 173.326 bits (438), Expect = 9.292e-44 Identity = 134/449 (29.84%), Postives = 208/449 (46.33%), Query Frame = 3
Query: 2028 NGENMIWATIDSSGGRISLALSDINLTCPPNSFAPGISEPIFLATCNSEQDLPNLSANETLLSPVVVCGPTNVIAFKPFILNIPHCAYNTDSGNWAISVLTSYSPLKQKPY---WQKYLDLDAEDKDSPPGYAQLAKDRLFLITNQLQRFCVVGSSYR---NKRATKVLRIAAYCTGLDRRHADEQIVVRLYLIPDIAECISKVHNFETNRLGARLVTNQKQFFCEDEAGNITVVISDLA-MDWQASSANNYQEIPFKDVWHSP--TLHCSFNFIKRLINANSSELKISVNSLDFNWFCTLSIYQTNSHHNKQTVLLSTPNGSSHTSISATSTQFSNYSAGGSQSFPYFVDDCSKT-NFESVFKLPEQTKIKLCKLLDSLTPLDNDWRQLARHLSITRSLQFFSNKLSSTEILLDLWEAQNHSRKSLNNLIDILRKMGRLDCVAILEKD 3344
NG N + T + GGR++L + I+L PP + G I+L E L+ +TLLSPVV CGP V+ +P IL + HC+ + NWAI LK++ Y W+ L L ED S P Y QL + + T QL RF +VG S KR +L AYC+ L+ +R+Y D + + +V E +LG RL+ +D N+ + I D+ W++ YQEIPF +W TLHCSF ++ S+++ D + CTL ++Q ++ + I + F +++CS S F++P + K+C LD+ P DWR LA+ L + R + FF++K S T ++LDLWE Q+ +LN L ++ ++G+ + + L D
Sbjct: 457 NG-NTSYGTFNFLGGRLTLPNTGISLLIPPEAIPRGKIYEIYLTIQKKEDMRLPLAGCQTLLSPVVSCGPPGVMLTRPVILCMDHCS-DACLENWAIR-------LKKQSYEGTWEDVL-LLGEDLLSEPYYCQLEAETCRVFTEQLGRFALVGESLSMAAAKRLKLLLFAPAYCSTLEYN-------IRVYCTDDTQDLLKEVMQME-RQLGGRLIDEPHVLLFKDSYHNLRLSIHDMPHTHWRSKLLAGYQEIPFYHIWSGSQRTLHCSFTLERQ-----------SLSTSDLS--CTLCVWQVEGEGQSFSLDFNIAK-----DIRPLDSDF------------LLLENCSPALAGPSAFQIPYLIRQKICSSLDAPCPNGADWRLLAQRLKLDRHMSFFASKSSPTSVILDLWETQHFHSGNLNQLAAVMAEIGKQEAMIFLVSD 857 HSP 2 Score: 115.161 bits (287), Expect = 1.787e-25 Identity = 77/281 (27.40%), Postives = 131/281 (46.62%), Query Frame = 3
Query: 375 VPKFIQQPKSMYYVSKSHPAVITCIAQPVSHVNIFCADKQYSYMNEEV------SATGLKVIKMDNEGRLAVKGNRWKFSLEVQHKDVIEWFSEYRCHCEAWNQIEQLQKVKKVESSSAVIYDSYINKDFKTVPKNQKVSVRGSVKLSCIPPDAKPPAEIHWVKNGEKITGKSHPQFEINEYGELLLSNIRLTDSGNYSCVASSFGLERH-ATAQILVFEVGQWSDWSEWTGICPNICSKGSNCPKVCSTSRQQRVRYCNQIK--NQKANCIGSEIEYKRC 1190
+P F+ +P +Y V K+ P +TC + P + + C + ++ + ++ + ATGL V+++ K + Q + I +Y C C AW+ +S A + +Y+ K+F+ P ++V++ + L C PP+ PPAE+ W +N E I K+ P F I L++ RL D+GNY+CVA + R ++A ++V+ G WS+WS+W S C CS R R C Q +C G +++ C
Sbjct: 51 LPHFLIEPDDVYIV-KNKPVTLTCRSTPATQIYFKC-NGEWVHQDQHLIDRDVDPATGLPVMQV-------------KIDISRQQVEKIFGLEDYWCQCVAWS------TTGTQKSQKAFVRIAYLRKNFEEEPLGKEVALDQELLLRCHPPEGVPPAEVEWQRNEELIDPKTDPNFFITTDHNLIIKQTRLADTGNYTCVAKNIVARRKSSSATVIVYVDGGWSEWSKW-----------SPCGADCSMWRS---RECTQPTPGTGGKDCQGLDLQSLNC 296
BLAST of Unc-5 netrin receptor B vs. Ensembl Xenopus
Match: UNC5B (unc-5 netrin receptor B [Source:NCBI gene;Acc:100492290]) HSP 1 Score: 316.235 bits (809), Expect = 2.040e-91 Identity = 273/1014 (26.92%), Postives = 449/1014 (44.28%), Query Frame = 3
Query: 369 EGVPKFIQQPKSMYYVSKSHPAVITCIAQPVSHVNIFCADKQYSYMNEEVSATGLKVIKMDNEGRLAVKGNRWKFSLEVQHKDVIEWFS--EYRCHCEAWNQIEQLQKVKKVESSSAVIYDSYINKDFKTVPKNQKVSVRGSVKLSCIPPDAKPPAEIHWVKNGEKITGKSHPQFEINEYGELLLSNIRLTDSGNYSCVASSFGLERHAT-AQILVFEVGQWSDWSEWTGICPNICSKGSNCPKVCSTSRQQRVRYCNQIK--NQKANCIGSEIEYKRCDLICDPNL-WTFWSEWSKCSGNPCKKERTRQC---TTNNCGKASS---VEIDNCTLAECGGFVASFINSNKKYPESSTSIYI--THDVAMYIGLFVAVSVFLMVVAIIFCLIRRRVIGFSPNRVWRYSTTANGIQMFYPDXXXXXXXXXXXXXXXXXXDINQPSLYRSIVLPNSLPFLPSNQSDASSNSAYTDVGNDITYIQRNHLPSLPMIATPLLSSMKPTLKIRPSYSDSKVSSTLYPQMGLVKHVSTLPI-PVSSSLSDHYQELGNTDNETSDQSVTEPCLPYNFNGENMIWATIDSSGGRISLALSDINLTCPPNSFAPGISEPIFLATCNSEQDLPNLSANETLLSPVVVCGPTNVIAFKPFILNIPHCAYNTDSGNWAISVLTSYSPLKQKPYWQKYLDLDAEDKDSPPGYAQLAKDRLFLITNQLQRFCVVGSSYRNKRATKVLRIAAY----CTGLDRRHADEQIVVRLYLIPDIAECISKVHNFETNRLGARLVTNQKQFFCEDEAGNITVVISDLAMD-WQASSANNYQEIPFKDVWHSP--TLHCSFNFIKRLINANSSELKISVNSLDFNWFCTLSIYQTNSHHNKQTVLLSTPNGSSHTSISATSTQFSNYSAGGSQSFPYFVDDCSKTNFESVFKLPEQTKIKLCKLLDSLTPLDNDWRQLARHLSITRSLQFFSNKLSSTEILLDLWEAQNHSRKSLNNLIDILRKMGRLDCVAILEKD 3344
E +P F+ +P+ Y V K+ P + C A P + + C + ++ N+ ++ ++D L V+ + +EV + V E F +Y C C AW+ +S A + +Y+ K+F P ++V++ L C PP+ PPAE+ W+KN E I F I L++ RL+D+ NY+CVA + +R +T A ++VF G WS W+EW S C C Q+R R C N C G + + C+ +C + WT WS+WS CS C R+R+C T N GK S ++ NCT C NK+ + S + T DVA+Y GL VA+ + ++++ + ++ RR + S G F+P +N +++ NS P+ Q D ++N+ + Y ++ +PM +PLL + P LKI+ ++ S V S+ G+ L + P + SD+ N N + T+ L + N + T S GGR++ + ++L P + G ++L E + +T+LSP++ CGPT ++ KP IL +PHCA + + +W + + T + W++ + L+ E ++P Y QL ++ +QL + VG SY +K A K L++A + CT L+ +++Y + D + + +V E LG LV + K +D N+ + I D+ W++ YQEIPF +W TLHC+F + + A KI V ++ I+Q H + + + S SHT S T TQ Y+ FK+P + K+C LD+ NDWR LA+ L + R L +F+ K S T ++LDLWEA + LN L L +MG+ + + ++ D
Sbjct: 35 ESLPHFLLEPEDAYIV-KNKPVELVCKANPATQIYFKC-NGEWVNQNDHITKE-----RVDEVTGLVVR----EVQIEVSRQQVEELFGLEDYWCQCVAWS------SAGTTKSKRAYVRIAYLRKNFDQEPLGKEVALEQEALLQCRPPEGVPPAEVEWLKNEEIIDPTKDTNFLITIDHNLIIKQARLSDTANYTCVAKNIVAKRRSTTATVIVFVNGGWSSWTEW-----------SPCNNRCGHGWQKRTRTCTNPAPLNGGTMCEGQQYQKFACNTMCPVDGGWTEWSKWSACS-TECTHWRSRECNAPTPKNGGKDCSGMLLDSKNCTDGLC--------MQNKRVLGETKSHLLESTGDVALYAGLVVAIFIVIILLMAVGIVVYRRNCRELDTDITDSSAALTG--GFHP--------------------VN----FKTSRHDNSHLIHPAMQPDLTANAG---IYRGHMYALQDSADKIPMTNSPLLDPL-PNLKIK-VFNSSTVGSS----PGIHDGNDLLGVKPTGTYPSDN-----NIMNARNKNMSTQHLLTLPRDSSNSVTGTFGSLGGRLTFPNTGVSLLIPQGAIPQGKYYEMYLMINKRENTVLPSEGTQTILSPIITCGPTGLLLCKPVILTVPHCA-DIATSDWILQLKTQ----SHQGNWEEVVTLNEETLNTP-CYCQLESHSCHILLDQLGTYAFVGESY-SKSAIKRLQLAIFAPMLCTSLEYN-------LKVYCVEDTPDALKEVLELEKT-LGGYLVEDPKPLMFKDSYHNLRLSIHDIPHSLWRSKLLAKYQEIPFYHIWSGSQRTLHCTFTLERYSLAATELTCKICVRQVEGEG----QIFQL--HTSLEENVKSFDPFCSHTENSVT-TQLGPYA----------------------FKIPYSIRQKICNSLDAPNSRGNDWRLLAQKLCMDRYLNYFATKASPTGVILDLWEALHQDDGDLNTLASALEEMGKSEMMLVMATD 927
BLAST of Unc-5 netrin receptor B vs. Ensembl Xenopus
Match: UNC5B (unc-5 netrin receptor B [Source:NCBI gene;Acc:100492290]) HSP 1 Score: 315.849 bits (808), Expect = 3.590e-91 Identity = 273/1014 (26.92%), Postives = 449/1014 (44.28%), Query Frame = 3
Query: 369 EGVPKFIQQPKSMYYVSKSHPAVITCIAQPVSHVNIFCADKQYSYMNEEVSATGLKVIKMDNEGRLAVKGNRWKFSLEVQHKDVIEWFS--EYRCHCEAWNQIEQLQKVKKVESSSAVIYDSYINKDFKTVPKNQKVSVRGSVKLSCIPPDAKPPAEIHWVKNGEKITGKSHPQFEINEYGELLLSNIRLTDSGNYSCVASSFGLERHAT-AQILVFEVGQWSDWSEWTGICPNICSKGSNCPKVCSTSRQQRVRYCNQIK--NQKANCIGSEIEYKRCDLICDPNL-WTFWSEWSKCSGNPCKKERTRQC---TTNNCGKASS---VEIDNCTLAECGGFVASFINSNKKYPESSTSIYI--THDVAMYIGLFVAVSVFLMVVAIIFCLIRRRVIGFSPNRVWRYSTTANGIQMFYPDXXXXXXXXXXXXXXXXXXDINQPSLYRSIVLPNSLPFLPSNQSDASSNSAYTDVGNDITYIQRNHLPSLPMIATPLLSSMKPTLKIRPSYSDSKVSSTLYPQMGLVKHVSTLPI-PVSSSLSDHYQELGNTDNETSDQSVTEPCLPYNFNGENMIWATIDSSGGRISLALSDINLTCPPNSFAPGISEPIFLATCNSEQDLPNLSANETLLSPVVVCGPTNVIAFKPFILNIPHCAYNTDSGNWAISVLTSYSPLKQKPYWQKYLDLDAEDKDSPPGYAQLAKDRLFLITNQLQRFCVVGSSYRNKRATKVLRIAAY----CTGLDRRHADEQIVVRLYLIPDIAECISKVHNFETNRLGARLVTNQKQFFCEDEAGNITVVISDLAMD-WQASSANNYQEIPFKDVWHSP--TLHCSFNFIKRLINANSSELKISVNSLDFNWFCTLSIYQTNSHHNKQTVLLSTPNGSSHTSISATSTQFSNYSAGGSQSFPYFVDDCSKTNFESVFKLPEQTKIKLCKLLDSLTPLDNDWRQLARHLSITRSLQFFSNKLSSTEILLDLWEAQNHSRKSLNNLIDILRKMGRLDCVAILEKD 3344
E +P F+ +P+ Y V K+ P + C A P + + C + ++ N+ ++ ++D L V+ + +EV + V E F +Y C C AW+ +S A + +Y+ K+F P ++V++ L C PP+ PPAE+ W+KN E I F I L++ RL+D+ NY+CVA + +R +T A ++VF G WS W+EW S C C Q+R R C N C G + + C+ +C + WT WS+WS CS C R+R+C T N GK S ++ NCT C NK+ + S + T DVA+Y GL VA+ + ++++ + ++ RR + S G F+P +N +++ NS P+ Q D ++N+ + Y ++ +PM +PLL + P LKI+ ++ S V S+ G+ L + P + SD+ N N + T+ L + N + T S GGR++ + ++L P + G ++L E + +T+LSP++ CGPT ++ KP IL +PHCA + + +W + + T + W++ + L+ E ++P Y QL ++ +QL + VG SY +K A K L++A + CT L+ +++Y + D + + +V E LG LV + K +D N+ + I D+ W++ YQEIPF +W TLHC+F + + A KI V ++ I+Q H + + + S SHT S T TQ Y+ FK+P + K+C LD+ NDWR LA+ L + R L +F+ K S T ++LDLWEA + LN L L +MG+ + + ++ D
Sbjct: 48 ESLPHFLLEPEDAYIV-KNKPVELVCKANPATQIYFKC-NGEWVNQNDHITKE-----RVDEVTGLVVR----EVQIEVSRQQVEELFGLEDYWCQCVAWS------SAGTTKSKRAYVRIAYLRKNFDQEPLGKEVALEQEALLQCRPPEGVPPAEVEWLKNEEIIDPTKDTNFLITIDHNLIIKQARLSDTANYTCVAKNIVAKRRSTTATVIVFVNGGWSSWTEW-----------SPCNNRCGHGWQKRTRTCTNPAPLNGGTMCEGQQYQKFACNTMCPVDGGWTEWSKWSACS-TECTHWRSRECNAPTPKNGGKDCSGMLLDSKNCTDGLC--------MQNKRVLGETKSHLLESTGDVALYAGLVVAIFIVIILLMAVGIVVYRRNCRELDTDITDSSAALTG--GFHP--------------------VN----FKTSRHDNSHLIHPAMQPDLTANAG---IYRGHMYALQDSADKIPMTNSPLLDPL-PNLKIK-VFNSSTVGSS----PGIHDGNDLLGVKPTGTYPSDN-----NIMNARNKNMSTQHLLTLPRDSSNSVTGTFGSLGGRLTFPNTGVSLLIPQGAIPQGKYYEMYLMINKRENTVLPSEGTQTILSPIITCGPTGLLLCKPVILTVPHCA-DIATSDWILQLKTQ----SHQGNWEEVVTLNEETLNTP-CYCQLESHSCHILLDQLGTYAFVGESY-SKSAIKRLQLAIFAPMLCTSLEYN-------LKVYCVEDTPDALKEVLELEKT-LGGYLVEDPKPLMFKDSYHNLRLSIHDIPHSLWRSKLLAKYQEIPFYHIWSGSQRTLHCTFTLERYSLAATELTCKICVRQVEGEG----QIFQL--HTSLEENVKSFDPFCSHTENSVT-TQLGPYA----------------------FKIPYSIRQKICNSLDAPNSRGNDWRLLAQKLCMDRYLNYFATKASPTGVILDLWEALHQDDGDLNTLASALEEMGKSEMMLVMATD 940
BLAST of Unc-5 netrin receptor B vs. Ensembl Xenopus
Match: UNC5B (unc-5 netrin receptor B [Source:NCBI gene;Acc:100492290]) HSP 1 Score: 314.694 bits (805), Expect = 6.722e-91 Identity = 271/1012 (26.78%), Postives = 445/1012 (43.97%), Query Frame = 3
Query: 369 EGVPKFIQQPKSMYYVSKSHPAVITCIAQPVSHVNIFCADKQYSYMNEEVSATGLKVIKMDNEGRLAVKGNRWKFSLEVQHKDVIEWFS--EYRCHCEAWNQIEQLQKVKKVESSSAVIYDSYINKDFKTVPKNQKVSVRGSVKLSCIPPDAKPPAEIHWVKNGEKITGKSHPQFEINEYGELLLSNIRLTDSGNYSCVASSFGLERHAT-AQILVFEVGQWSDWSEWTGICPNICSKGSNCPKVCSTSRQQRVRYCNQIK--NQKANCIGSEIEYKRCDLICDPNL-WTFWSEWSKCSGNPCKKERTRQC---TTNNCGKASS---VEIDNCTLAECGGFVASFINSNKKYPESSTSIYITHDVAMYIGLFVAVSVFLMVVAIIFCLIRRRVIGFSPNRVWRYSTTANGIQMFYPDXXXXXXXXXXXXXXXXXXDINQPSLYRSIVLPNSLPFLPSNQSDASSNSAYTDVGNDITYIQRNHLPSLPMIATPLLSSMKPTLKIRPSYSDSKVSSTLYPQMGLVKHVSTLPI-PVSSSLSDHYQELGNTDNETSDQSVTEPCLPYNFNGENMIWATIDSSGGRISLALSDINLTCPPNSFAPGISEPIFLATCNSEQDLPNLSANETLLSPVVVCGPTNVIAFKPFILNIPHCAYNTDSGNWAISVLTSYSPLKQKPYWQKYLDLDAEDKDSPPGYAQLAKDRLFLITNQLQRFCVVGSSYRNKRATKVLRIAAY----CTGLDRRHADEQIVVRLYLIPDIAECISKVHNFETNRLGARLVTNQKQFFCEDEAGNITVVISDLAMD-WQASSANNYQEIPFKDVWHSP--TLHCSFNFIKRLINANSSELKISVNSLDFNWFCTLSIYQTNSHHNKQTVLLSTPNGSSHTSISATSTQFSNYSAGGSQSFPYFVDDCSKTNFESVFKLPEQTKIKLCKLLDSLTPLDNDWRQLARHLSITRSLQFFSNKLSSTEILLDLWEAQNHSRKSLNNLIDILRKMGRLDCVAILEKD 3344
E +P F+ +P+ Y V K+ P + C A P + + C + ++ N+ ++ ++D L V+ + +EV + V E F +Y C C AW+ +S A + +Y+ K+F P ++V++ L C PP+ PPAE+ W+KN E I F I L++ RL+D+ NY+CVA + +R +T A ++VF G WS W+EW S C C Q+R R C N C G + + C+ +C + WT WS+WS CS C R+R+C T N GK S ++ NCT C + S T DVA+Y GL VA+ + ++++ + ++ RR + S G F+P +N +++ NS P+ Q D ++N+ + Y ++ +PM +PLL + P LKI+ ++ S V S+ G+ L + P + SD+ N N + T+ L + N + T S GGR++ + ++L P + G ++L E + +T+LSP++ CGPT ++ KP IL +PHCA + + +W + + T + W++ + L+ E ++P Y QL ++ +QL + VG SY +K A K L++A + CT L+ +++Y + D + + +V E LG LV + K +D N+ + I D+ W++ YQEIPF +W TLHC+F + + A KI V ++ I+Q H + + + S SHT S T TQ Y+ FK+P + K+C LD+ NDWR LA+ L + R L +F+ K S T ++LDLWEA + LN L L +MG+ + + ++ D
Sbjct: 48 ESLPHFLLEPEDAYIV-KNKPVELVCKANPATQIYFKC-NGEWVNQNDHITKE-----RVDEVTGLVVR----EVQIEVSRQQVEELFGLEDYWCQCVAWS------SAGTTKSKRAYVRIAYLRKNFDQEPLGKEVALEQEALLQCRPPEGVPPAEVEWLKNEEIIDPTKDTNFLITIDHNLIIKQARLSDTANYTCVAKNIVAKRRSTTATVIVFVNGGWSSWTEW-----------SPCNNRCGHGWQKRTRTCTNPAPLNGGTMCEGQQYQKFACNTMCPVDGGWTEWSKWSACS-TECTHWRSRECNAPTPKNGGKDCSGMLLDSKNCTDGLCMQMLES-----------------TGDVALYAGLVVAIFIVIILLMAVGIVVYRRNCRELDTDITDSSAALTG--GFHP--------------------VN----FKTSRHDNSHLIHPAMQPDLTANAG---IYRGHMYALQDSADKIPMTNSPLLDPL-PNLKIK-VFNSSTVGSS----PGIHDGNDLLGVKPTGTYPSDN-----NIMNARNKNMSTQHLLTLPRDSSNSVTGTFGSLGGRLTFPNTGVSLLIPQGAIPQGKYYEMYLMINKRENTVLPSEGTQTILSPIITCGPTGLLLCKPVILTVPHCA-DIATSDWILQLKTQ----SHQGNWEEVVTLNEETLNTP-CYCQLESHSCHILLDQLGTYAFVGESY-SKSAIKRLQLAIFAPMLCTSLEYN-------LKVYCVEDTPDALKEVLELEKT-LGGYLVEDPKPLMFKDSYHNLRLSIHDIPHSLWRSKLLAKYQEIPFYHIWSGSQRTLHCTFTLERYSLAATELTCKICVRQVEGEG----QIFQL--HTSLEENVKSFDPFCSHTENSVT-TQLGPYA----------------------FKIPYSIRQKICNSLDAPNSRGNDWRLLAQKLCMDRYLNYFATKASPTGVILDLWEALHQDDGDLNTLASALEEMGKSEMMLVMATD 929
BLAST of Unc-5 netrin receptor B vs. Ensembl Xenopus
Match: UNC5B (unc-5 netrin receptor B [Source:NCBI gene;Acc:100492290]) HSP 1 Score: 312.383 bits (799), Expect = 4.653e-90 Identity = 270/1019 (26.50%), Postives = 439/1019 (43.08%), Query Frame = 3
Query: 369 EGVPKFIQQPKSMYYVSKSHPAVITCIAQPVSHVNIFCADKQYSYMNEEVSATGLKVIKMDNEGRLAVKGNRWKFSLEVQHKDVIEWFS--EYRCHCEAWNQIEQLQKVKKVESSSAVIYDSYINKDFKTVPKNQKVSVRGSVKLSCIPPDAKPPAEIHWVKNGEKITGKSHPQFEINEYGELLLSNIRLTDSGNYSCVASSFGLERHAT-AQILVFEVGQWSDWSEWTGICPNICSKGSNCPKVCSTSRQQRVRYCNQIK--NQKANCIGSEIEYKRCDLICDPNL-WTFWSEWSKCSGNPCKKERTRQC---TTNNCGKASS---VEIDNCTLAECGGFVASFINSNKKYPESSTSIYITHDVAMYIGLFVAVSVFLMVVAIIFCLIRRRVIGFSPNRVWRYSTTANGIQMFYPDXXXXXXXXXXXXXXXXXXDINQPSLYRSIVLPNSLPFLPSNQSDASSNSAYTDVGNDITYIQRNHLPSL-------PMIATPLLSSMKPTLKIRPSYSDSKVSSTLYPQMGLVKHVSTLPI-PVSSSLSDHYQELGNTDNETSDQSVTEPCLPYNFNGENMIWATIDSSGGRISLALSDINLTCPPNSFAPGISEPIFLATCNSEQDLPNLSANETLLSPVVVCGPTNVIAFKPFILNIPHCAYNTDSGNWAISVLTSYSPLKQKPYWQKYLDLDAEDKDSPPGYAQLAKDRLFLITNQLQRFCVVGSSYRNKRATKVLRIAAY----CTGLDRRHADEQIVVRLYLIPDIAECISKVHNFETNRLGARLVTNQKQFFCEDEAGNITVVISDLAMD-WQASSANNYQEIPFKDVWHSP--TLHCSFNFIKRLINANSSELKISVNSLDFNWFCTLSIYQTNSHHNKQTVLLSTPNGSSHTSISATSTQFSNYSAGGSQSFPYFVDDCSKTNFESVFKLPEQTKIKLCKLLDSLTPLDNDWRQLARHLSITRSLQFFSNKLSSTEILLDLWEAQNHSRKSLNNLIDILRKMGRLDCVAILEKD 3344
E +P F+ +P+ Y V K+ P + C A P + + C + ++ N+ ++ ++D L V+ + +EV + V E F +Y C C AW+ +S A + +Y+ K+F P ++V++ L C PP+ PPAE+ W+KN E I F I L++ RL+D+ NY+CVA + +R +T A ++VF G WS W+EW S C C Q+R R C N C G + + C+ +C + WT WS+WS CS C R+R+C T N GK S ++ NCT C + S T DVA+Y GL VA+ + ++++ + ++ RR + S G F+P + F S A+ + G I R H+ +L PM +PLL + P LKI+ ++ S V S+ G+ L + P + SD+ N N + T+ L + N + T S GGR++ + ++L P + G ++L E + +T+LSP++ CGPT ++ KP IL +PHCA + + +W + + T + W++ + L+ E ++P Y QL ++ +QL + VG SY +K A K L++A + CT L+ +++Y + D + + +V E LG LV + K +D N+ + I D+ W++ YQEIPF +W TLHC+F + + A KI V ++ I+Q ++ + ++S SHT S T TQ Y+ FK+P + K+C LD+ NDWR LA+ L + R L +F+ K S T ++LDLWEA + LN L L +MG+ + + ++ D
Sbjct: 48 ESLPHFLLEPEDAYIV-KNKPVELVCKANPATQIYFKC-NGEWVNQNDHITKE-----RVDEVTGLVVR----EVQIEVSRQQVEELFGLEDYWCQCVAWS------SAGTTKSKRAYVRIAYLRKNFDQEPLGKEVALEQEALLQCRPPEGVPPAEVEWLKNEEIIDPTKDTNFLITIDHNLIIKQARLSDTANYTCVAKNIVAKRRSTTATVIVFVNGGWSSWTEW-----------SPCNNRCGHGWQKRTRTCTNPAPLNGGTMCEGQQYQKFACNTMCPVDGGWTEWSKWSACS-TECTHWRSRECNAPTPKNGGKDCSGMLLDSKNCTDGLCMQMLES-----------------TGDVALYAGLVVAIFIVIILLMAVGIVVYRRNCRELDTDITDSSAALTG--GFHP-----------------------------------VNFKTSRHGKANVPDLTANAG-----IYRGHMYALQDSADKIPMTNSPLLDPL-PNLKIK-VFNSSTVGSS----PGIHDGNDLLGVKPTGTYPSDN-----NIMNARNKNMSTQHLLTLPRDSSNSVTGTFGSLGGRLTFPNTGVSLLIPQGAIPQGKYYEMYLMINKRENTVLPSEGTQTILSPIITCGPTGLLLCKPVILTVPHCA-DIATSDWILQLKTQ----SHQGNWEEVVTLNEETLNTP-CYCQLESHSCHILLDQLGTYAFVGESY-SKSAIKRLQLAIFAPMLCTSLEYN-------LKVYCVEDTPDALKEVLELEKT-LGGYLVEDPKPLMFKDSYHNLRLSIHDIPHSLWRSKLLAKYQEIPFYHIWSGSQRTLHCTFTLERYSLAATELTCKICVRQVEGEG----QIFQLHTSLEEAPTVISFDPFCSHTENSVT-TQLGPYA----------------------FKIPYSIRQKICNSLDAPNSRGNDWRLLAQKLCMDRYLNYFATKASPTGVILDLWEALHQDDGDLNTLASALEEMGKSEMMLVMATD 925
BLAST of Unc-5 netrin receptor B vs. Ensembl Xenopus
Match: UNC5B (unc-5 netrin receptor B [Source:NCBI gene;Acc:100492290]) HSP 1 Score: 311.997 bits (798), Expect = 7.017e-90 Identity = 271/1014 (26.73%), Postives = 446/1014 (43.98%), Query Frame = 3
Query: 369 EGVPKFIQQPKSMYYVSKSHPAVITCIAQPVSHVNIFCADKQYSYMNEEVSATGLKVIKMDNEGRLAVKGNRWKFSLEVQHKDVIEWFS--EYRCHCEAWNQIEQLQKVKKVESSSAVIYDSYINKDFKTVPKNQKVSVRGSVKLSCIPPDAKPPAEIHWVKNGEKITGKSHPQFEINEYGELLLSNIRLTDSGNYSCVASSFGLERHA-TAQILVFEVGQWSDWSEWTGICPNICSKGSNCPKVCSTSRQQRVRYCNQIK--NQKANCIGSEIEYKRCDLICDPN-LWTFWSEWSKCSGNPCKKERTRQC---TTNNCGKASS---VEIDNCTLAECGGFVASFINSNKKYPESSTSIYI--THDVAMYIGLFVAVSVFLMVVAIIFCLIRRRVIGFSPNRVWRYSTTANGIQMFYPDXXXXXXXXXXXXXXXXXXDINQPSLYRSIVLPNSLPFLPSNQSDASSNSAYTDVGNDITYIQRNHLPSLPMIATPLLSSMKPTLKIRPSYSDSKVSSTLYPQMGLVKHVSTLPI-PVSSSLSDHYQELGNTDNETSDQSVTEPCLPYNFNGENMIWATIDSSGGRISLALSDINLTCPPNSFAPGISEPIFLATCNSEQDLPNLSANETLLSPVVVCGPTNVIAFKPFILNIPHCAYNTDSGNWAISVLTSYSPLKQKPYWQKYLDLDAEDKDSPPGYAQLAKDRLFLITNQLQRFCVVGSSYRNKRATKVLRIAAY----CTGLDRRHADEQIVVRLYLIPDIAECISKVHNFETNRLGARLVTNQKQFFCEDEAGNITVVISDLAMD-WQASSANNYQEIPFKDVWHSP--TLHCSFNFIKRLINANSSELKISVNSLDFNWFCTLSIYQTNSHHNKQTVLLSTPNGSSHTSISATSTQFSNYSAGGSQSFPYFVDDCSKTNFESVFKLPEQTKIKLCKLLDSLTPLDNDWRQLARHLSITRSLQFFSNKLSSTEILLDLWEAQNHSRKSLNNLIDILRKMGRLDCVAILEKD 3344
E +P F+ +P+ Y V K+ P + C A P + + C + ++ N+ ++ ++D L V+ + +EV + V E F +Y C C AW+ +S A + +Y+ K+F P ++V++ L C PP+ PPAE+ W+KN E I F I L++ RL+D+ NY+CVA + +R + TA ++VF G WS W+EW S C C Q+R R C N C G + + C+ +C + WT WS+WS CS C R+R+C T N GK S ++ NCT C NK+ + S + T DVA+Y GL VA+ + ++++ + ++ RR + S G F+P +N +++ NS P+ Q D ++N+ + Y ++ +PM +PLL + P LKI+ ++ S V S+ G+ L + P + SD+ N N + T+ L + N + T S GGR++ + ++L P + G ++L E + +T+LSP++ CGPT ++ KP IL +PHCA + + +W + + T + W++ + L+ E ++ P Y QL ++ +QL + VG SY +K A K L++A + CT L+ +++Y + D + + +V E LG LV + K +D N+ + I D+ W++ YQEIPF +W TLHC+F + + A KI V ++ I+Q HTS+ + N S +Q PY FK+P + K+C LD+ NDWR LA+ L + R L +F+ K S T ++LDLWEA + LN L L +MG+ + + ++ D
Sbjct: 49 ESLPHFLLEPEDAYIV-KNKPVELVCKANPATQIYFKC-NGEWVNQNDHITKE-----RVDEVTGLVVR----EVQIEVSRQQVEELFGLEDYWCQCVAWS------SAGTTKSKRAYVRIAYLRKNFDQEPLGKEVALEQEALLQCRPPEGVPPAEVEWLKNEEIIDPTKDTNFLITIDHNLIIKQARLSDTANYTCVAKNIVAKRRSTTATVIVFVNGGWSSWTEW-----------SPCNNRCGHGWQKRTRTCTNPAPLNGGTMCEGQQYQKFACNTMCPVDGGWTEWSKWSACS-TECTHWRSRECNAPTPKNGGKDCSGMLLDSKNCTDGLC--------MQNKRVLGETKSHLLESTGDVALYAGLVVAIFIVIILLMAVGIVVYRRNCRELDTDITDSSAALTG--GFHP--------------------VN----FKTSRHDNSHLIHPAMQPDLTANAG---IYRGHMYALQDSADKIPMTNSPLLDPL-PNLKIK-VFNSSTVGSS----PGIHDGNDLLGVKPTGTYPSDN-----NIMNARNKNMSTQHLLTLPRDSSNSVTGTFGSLGGRLTFPNTGVSLLIPQGAIPQGKYYEMYLMINKRENTVLPSEGTQTILSPIITCGPTGLLLCKPVILTVPHCA-DIATSDWILQLKTQ----SHQGNWEEVVTLNEETLNT-PCYCQLESHSCHILLDQLGTYAFVGESY-SKSAIKRLQLAIFAPMLCTSLEYN-------LKVYCVEDTPDALKEVLELEKT-LGGYLVEDPKPLMFKDSYHNLRLSIHDIPHSLWRSKLLAKYQEIPFYHIWSGSQRTLHCTFTLERYSLAATELTCKICVRQVEGEG----QIFQL------------------HTSLE----EVRNNSV-TTQLGPY------------AFKIPYSIRQKICNSLDAPNSRGNDWRLLAQKLCMDRYLNYFATKASPTGVILDLWEALHQDDGDLNTLASALEEMGKSEMMLVMATD 931
BLAST of Unc-5 netrin receptor B vs. Ensembl Mouse
Match: Unc5b (unc-5 netrin receptor B [Source:MGI Symbol;Acc:MGI:894703]) HSP 1 Score: 295.049 bits (754), Expect = 5.730e-84 Identity = 274/1017 (26.94%), Postives = 442/1017 (43.46%), Query Frame = 3
Query: 369 EGVPKFIQQPKSMYYVSKSHPAVITCIAQPVSHVNIFCADKQYSYMNEEVS------ATGLKVIKMDNEGRLAVKGNRWKFSLEVQHKDVIEWFS--EYRCHCEAWNQIEQLQKVKKVESSSAVIYDSYINKDFKTVPKNQKVSVRGSVKLSCIPPDAKPPAEIHWVKNGEKITGKSHPQFEINEYGELLLSNIRLTDSGNYSCVASSFGLERHAT-AQILVFEVGQWSDWSEWTGICPNICSKGSNCPKVCSTSRQQRVRYCNQIK--NQKANCIGSEIEYKRCDLICDPN-LWTFWSEWSKCSGNPCKKERTRQCTT---NNCGKASS---VEIDNCTLAECGGFVASFINSNKKYPESSTSIYITHDVAMYIGLFVAVSVFLMVVAIIFCLIRRRVIGFSPNRVWRYSTTANGIQMFYPDXXXXXXXXXXXXXXXXXXDINQPSLYRSIVLPNSLPFLPSNQSDASSNSAYTDVGNDITYIQRNHLPSLPMIATPLLSSMKPTLKIRPSYSDSKVSSTLYPQMGLVKHVSTLPIPVSSSLSDHYQELGNTDNETSDQSVTEPCLPYNFNGENMIWATIDSSGGRISLALSDINLTCPPNSFAPGISEPIFLATCNSEQDLPNLSANETLLSPVVVCGPTNVIAFKPFILNIPHCAYNTDSGNWAISVLTSYSPLKQKPYWQKYLDLDAEDKDSPPGYAQLAKDRLFLITNQLQRFCVVGSSYRNKRATKVLRIA----AYCTGLDRRHADEQIVVRLYLIPDIAECISKVHNFETNRLGARLVTNQKQFFCEDEAGNITVVISDLA-MDWQASSANNYQEIPFKDVWHSP--TLHCSFNFIKRLINANSSELKISVNSLDFNWFCTLSIYQTNSHHNKQTVLLSTPNGSSHTSISATSTQFSNYSAGGSQSFPYFVDDCSKTNFESVFKLPEQTKIKLCKLLDSLTPLDNDWRQLARHLSITRSLQFFSNKLSSTEILLDLWEAQNHSRKSLNNLIDILRKMGRLDCVAILEKD 3344
E +P F+ +P+ Y V K+ P + C A P + + C + ++ N+ V+ ATGL+V ++ +EV + V E F +Y C C AW+ +S A I +Y+ K+F P ++V + V L C PP+ P AE+ W+KN + I F + L++ RL+D+ NY+CVA + +R +T A ++V+ G WS W+EW+ C N C +G Q+R R C N A C G + C +C + WT WS+WS CS C R+R+C N G+ S ++ NCT C +N K +P + + DVA+Y GL VAV V + V+ + ++ RR + S G F+P N P L P++ P L +A + Y ++ +PM +PLL + P+LKI+ Y+ S + S GL L + + + + + S ++ L + + + T GGR+SL + ++L P + G ++L +E LP ++T+LSP V CGPT ++ +P +L +PHCA +G+W + T + +W++ + LD E ++P Y QL ++ +QL + +G SY ++ A K L++A A CT L + +R+Y + D + +V E LG LV K +D N+ + + D+ W++ YQEIPF VW+ LHC+F + + + K+ V ++ I+Q + T L TP GS SA + +Q PY FK+P + K+C LD+ NDWR LA+ LS+ R L +F+ K S T ++LDLWEA+ LN+L L +MG+ + + + D
Sbjct: 45 EQLPYFLLEPQDAYIV-KNKPVELHCRAFPATQIYFKC-NGEWVSQNDHVTQESLDEATGLRVREVQ---------------IEVSRQQVEELFGLEDYWCQCVAWS------SSGTTKSRRAYIRIAYLRKNFDQEPLAKEVPLDHEVLLQCRPPEGVPVAEVEWLKNEDVIDPAQDTNFLLTIDHNLIIRQARLSDTANYTCVAKNIVAKRRSTTATVIVYVNGGWSSWAEWS-PCSNRCGRG----------WQKRTRTCTNPAPLNGGAFCEGQAFQKTACTTVCPVDGAWTEWSKWSACS-TECAHWRSRECMAPPPQNGGRDCSGTLLDSKNCTDGLCV-LNQRTLNDPKSHP-----LETSGDVALYAGLVVAVFVVVAVLMAVGVIVYRRNCRDFDTDITDSSAALTG--GFHP-------------VNFKTARPNNPQLLH----PSAPPDL----------TASAGIYRGPVYALQDSADKIPMTNSPLLDPL-PSLKIK-VYNSSTIGSG----SGLADGADLLGVLPPGTYPGDFSRDTHFLHLRSASLGSQHLLGLPRDPSSSVSGTFGCLGGRLSLPGTGVSLLVPNGAIPQGKFYDLYLHINKAESTLPLSEGSQTVLSPSVTCGPTGLLLCRPVVLTVPHCA-EVIAGDWIFQLKTQ----AHQGHWEEVVTLDEETLNTP-CYCQLEAKSCHILLDQLGTYVFMGESY-SRSAVKRLQLAIFAPALCTSL-------EYSLRVYCLEDTPVALKEVLELERT-LGGYLVEEPKPLLFKDSYHNLRLSLHDIPHAHWRSKLLAKYQEIPFYHVWNGSQRALHCTFTLERHSLASTEFTCKVCVRQVEGEG----QIFQLH------TTLAETPAGSLDALCSAPGNAIT------TQLGPY------------AFKIPLSIRQKICSSLDAPNSRGNDWRLLAQKLSMDRYLNYFATKASPTGVILDLWEARQQDDGDLNSLASALEEMGKSEMLVAMATD 942
BLAST of Unc-5 netrin receptor B vs. Ensembl Mouse
Match: Unc5c (unc-5 netrin receptor C [Source:MGI Symbol;Acc:MGI:1095412]) HSP 1 Score: 290.812 bits (743), Expect = 1.683e-82 Identity = 261/1016 (25.69%), Postives = 441/1016 (43.41%), Query Frame = 3
Query: 369 EGVPKFIQQPKSMYYVSKSHPAVITCIAQPVSHVNIFCADKQYSYMNEEVSATGLKVIKMDNEGRLAVKGNRWKFSLEVQHKDVIEWFS--EYRCHCEAWNQIEQLQKVKKVESSSAVIYDSYINKDFKTVPKNQKVSVRGSVKLSCIPPDAKPPAEIHWVKNGEKITGKSHPQFEINEYGELLLSNIRLTDSGNYSCVASSFGLERHA-TAQILVFEVGQWSDWSEWTGICPNICSKGSNCPKVCSTSRQQRVRYCNQIK--NQKANCIGSEIEYKRCDLICDPN-LWTFWSEWSKCSGNPCKKERTRQCTT---NNCGK---ASSVEIDNCTLAEC-GGFVASFINSNKKYPESS-TSIYITHDVAMYIGLFVAVSVFLMVVAIIFCLIRRRVIGFSPNRVWRYSTTANGIQMFYPDXXXXXXXXXXXXXXXXXXDI-NQPSLYRSIVLPNSLPFLPSNQSDASSNSAYTDVGNDITYIQRNHLPSLPMIATPLLSSMKPTLKIRPSYSDSKVSSTLYPQMGLVKHVSTLPIPVSSSLSDHYQELGNTDNETSDQSVTEPCLPYNFNGENMIWATIDSSGGRISLALSDINLTCPPNSFAPGISEPIFLATCNSEQDLPNLSANETLLSPVVVCGPTNVIAFKPFILNIPHCAYNTDSGNWAISVLTSYSPLKQKPYWQKYLD--LDAEDKDSPPGYAQLAKDRLFLITNQLQRFCVVGSSYRNKRATKVLRIAAY----CTGLDRRHADEQIVVRLYLIPDIAECISKVHNFETNRLGARLVTNQKQFFCEDEAGNITVVISDLAMD-WQASSANNYQEIPFKDVWHSP--TLHCSFNFIKRLINANSSELKISVNSLDFNWFCTLSIYQTNSHHNKQTVLLSTPNGSSHTSISATSTQFSNYSAGGSQSFPYFVDDCSKTNFESVFKLPEQTKIKLCKLLDSLTPLDNDWRQLARHLSITRSLQFFSNKLSSTEILLDLWEAQNHSRKSLNNLIDILRKMGRLDCVAILEKD 3344
E +P F+ +P+ Y V K+ P + C A P + + C + ++ + + V ++D L V+ + S+E+ + V E F +Y C C AW+ +S A + +Y+ K F+ P ++VS+ V L C PP+ P AE+ W+KN + I F I L++ RL+D+ NY+CVA + +R + TA ++V+ G WS W+EW+ +C + C +G Q+R R C N A C G ++ C +C + WT WS+WS C G C R R+CT N GK ++ NCT C GF+ ++ E +S + DVA+Y+G+ +AV+V L + ++ + R+ + + S G Q + + D+ + ++YR V A DV + I PM +P+L + P LKI+ S V+ PQ L + S L ++ SL ++ E N N++ + C + T +S GG + + S ++L P + G +++ E P + ++TLL+PVV CGP + +P IL + HCA + + +W I LK + ++ D + E+ + P Y QL + ++T L + +VG S K A K L++A + C+ L+ +R+Y + D + + +V E ++G +L+ K + N+ + I D+A W++ YQEIPF +W LHC+F + +N K+ V ++ I+Q N +++ + P ++I+ + S F +P + KLC LD+ +DWR LA L++ R L +F+ K S T ++LDLWEAQN +L+ L +L +MGR + V L +
Sbjct: 59 EPLPHFLIEPEEAYIV-KNKPVNLYCKASPATQIYFKC-NSEWVHQKDHVVDE-----RVDETSGLIVR----EVSIEISRQQVEELFGPEDYWCQCVAWS------SAGTTKSRKAYVRIAYLRKTFEQEPLGKEVSLEQEVLLQCRPPEGIPVAEVEWLKNEDIIDPAEDRNFYITIDHNLIIKQARLSDTANYTCVAKNIVAKRKSTTATVIVYVNGGWSTWTEWS-VCNSRCGRG----------YQKRTRTCTNPAPLNGGAFCEGQSVQKIACTTLCPVDGRWTSWSKWSTC-GTECTHWRRRECTAPAPKNGGKDCDGLVLQSKNCTDGLCMQGFIYPISTEHRPQNEYGFSSAPDSDDVALYVGIVIAVTVCLAITVVVALFVYRKNHRDFESDIIDSSALNGGFQ-------PVNIKAARQDLLAVPPDLTSAAAMYRGPVY------------------ALHDVSDKI-----------PMTNSPILDPL-PNLKIKVYNSSGAVT----PQDDLAEFSSKLSPQMTQSLLEN--EALNLKNQSLARQTDPSCTAF---------GTFNSLGGHLIIPNSGVSLLIPAGAIPQGRVYEMYVTVHRKENMRPPMEDSQTLLTPVVSCGPPGALLTRPVILTLHHCA-DPSTEDWKIQ-------LKNQAVQGQWEDVVVVGEENFTTPCYIQLDAEACHILTENLSTYALVGQS-TTKAAAKRLKLAIFGPLCCSSLEYS-------IRVYCLDDTQDALKEVLQLE-RQMGGQLLEEPKALHFKGSIHNLRLSIHDIAHSLWKSKLLAKYQEIPFYHIWSGSQRNLHCTFTLERLSLNTVELVCKLCVRQVEGEG----QIFQLNCTVSEEPTGIDLPLLDPASTITTVTG-------------------------PSAFSIPLPIRQKLCSSLDAPQTRGHDWRMLAHKLNLDRYLNYFATKSSPTGVILDLWEAQNFPDGNLSMLAAVLEEMGRHETVVSLAAE 947
BLAST of Unc-5 netrin receptor B vs. Ensembl Mouse
Match: Unc5c (unc-5 netrin receptor C [Source:MGI Symbol;Acc:MGI:1095412]) HSP 1 Score: 290.812 bits (743), Expect = 1.683e-82 Identity = 261/1016 (25.69%), Postives = 441/1016 (43.41%), Query Frame = 3
Query: 369 EGVPKFIQQPKSMYYVSKSHPAVITCIAQPVSHVNIFCADKQYSYMNEEVSATGLKVIKMDNEGRLAVKGNRWKFSLEVQHKDVIEWFS--EYRCHCEAWNQIEQLQKVKKVESSSAVIYDSYINKDFKTVPKNQKVSVRGSVKLSCIPPDAKPPAEIHWVKNGEKITGKSHPQFEINEYGELLLSNIRLTDSGNYSCVASSFGLERHA-TAQILVFEVGQWSDWSEWTGICPNICSKGSNCPKVCSTSRQQRVRYCNQIK--NQKANCIGSEIEYKRCDLICDPN-LWTFWSEWSKCSGNPCKKERTRQCTT---NNCGK---ASSVEIDNCTLAEC-GGFVASFINSNKKYPESS-TSIYITHDVAMYIGLFVAVSVFLMVVAIIFCLIRRRVIGFSPNRVWRYSTTANGIQMFYPDXXXXXXXXXXXXXXXXXXDI-NQPSLYRSIVLPNSLPFLPSNQSDASSNSAYTDVGNDITYIQRNHLPSLPMIATPLLSSMKPTLKIRPSYSDSKVSSTLYPQMGLVKHVSTLPIPVSSSLSDHYQELGNTDNETSDQSVTEPCLPYNFNGENMIWATIDSSGGRISLALSDINLTCPPNSFAPGISEPIFLATCNSEQDLPNLSANETLLSPVVVCGPTNVIAFKPFILNIPHCAYNTDSGNWAISVLTSYSPLKQKPYWQKYLD--LDAEDKDSPPGYAQLAKDRLFLITNQLQRFCVVGSSYRNKRATKVLRIAAY----CTGLDRRHADEQIVVRLYLIPDIAECISKVHNFETNRLGARLVTNQKQFFCEDEAGNITVVISDLAMD-WQASSANNYQEIPFKDVWHSP--TLHCSFNFIKRLINANSSELKISVNSLDFNWFCTLSIYQTNSHHNKQTVLLSTPNGSSHTSISATSTQFSNYSAGGSQSFPYFVDDCSKTNFESVFKLPEQTKIKLCKLLDSLTPLDNDWRQLARHLSITRSLQFFSNKLSSTEILLDLWEAQNHSRKSLNNLIDILRKMGRLDCVAILEKD 3344
E +P F+ +P+ Y V K+ P + C A P + + C + ++ + + V ++D L V+ + S+E+ + V E F +Y C C AW+ +S A + +Y+ K F+ P ++VS+ V L C PP+ P AE+ W+KN + I F I L++ RL+D+ NY+CVA + +R + TA ++V+ G WS W+EW+ +C + C +G Q+R R C N A C G ++ C +C + WT WS+WS C G C R R+CT N GK ++ NCT C GF+ ++ E +S + DVA+Y+G+ +AV+V L + ++ + R+ + + S G Q + + D+ + ++YR V A DV + I PM +P+L + P LKI+ S V+ PQ L + S L ++ SL ++ E N N++ + C + T +S GG + + S ++L P + G +++ E P + ++TLL+PVV CGP + +P IL + HCA + + +W I LK + ++ D + E+ + P Y QL + ++T L + +VG S K A K L++A + C+ L+ +R+Y + D + + +V E ++G +L+ K + N+ + I D+A W++ YQEIPF +W LHC+F + +N K+ V ++ I+Q N +++ + P ++I+ + S F +P + KLC LD+ +DWR LA L++ R L +F+ K S T ++LDLWEAQN +L+ L +L +MGR + V L +
Sbjct: 59 EPLPHFLIEPEEAYIV-KNKPVNLYCKASPATQIYFKC-NSEWVHQKDHVVDE-----RVDETSGLIVR----EVSIEISRQQVEELFGPEDYWCQCVAWS------SAGTTKSRKAYVRIAYLRKTFEQEPLGKEVSLEQEVLLQCRPPEGIPVAEVEWLKNEDIIDPAEDRNFYITIDHNLIIKQARLSDTANYTCVAKNIVAKRKSTTATVIVYVNGGWSTWTEWS-VCNSRCGRG----------YQKRTRTCTNPAPLNGGAFCEGQSVQKIACTTLCPVDGRWTSWSKWSTC-GTECTHWRRRECTAPAPKNGGKDCDGLVLQSKNCTDGLCMQGFIYPISTEHRPQNEYGFSSAPDSDDVALYVGIVIAVTVCLAITVVVALFVYRKNHRDFESDIIDSSALNGGFQ-------PVNIKAARQDLLAVPPDLTSAAAMYRGPVY------------------ALHDVSDKI-----------PMTNSPILDPL-PNLKIKVYNSSGAVT----PQDDLAEFSSKLSPQMTQSLLEN--EALNLKNQSLARQTDPSCTAF---------GTFNSLGGHLIIPNSGVSLLIPAGAIPQGRVYEMYVTVHRKENMRPPMEDSQTLLTPVVSCGPPGALLTRPVILTLHHCA-DPSTEDWKIQ-------LKNQAVQGQWEDVVVVGEENFTTPCYIQLDAEACHILTENLSTYALVGQS-TTKAAAKRLKLAIFGPLCCSSLEYS-------IRVYCLDDTQDALKEVLQLE-RQMGGQLLEEPKALHFKGSIHNLRLSIHDIAHSLWKSKLLAKYQEIPFYHIWSGSQRNLHCTFTLERLSLNTVELVCKLCVRQVEGEG----QIFQLNCTVSEEPTGIDLPLLDPASTITTVTG-------------------------PSAFSIPLPIRQKLCSSLDAPQTRGHDWRMLAHKLNLDRYLNYFATKSSPTGVILDLWEAQNFPDGNLSMLAAVLEEMGRHETVVSLAAE 947
BLAST of Unc-5 netrin receptor B vs. Ensembl Mouse
Match: Unc5b (unc-5 netrin receptor B [Source:MGI Symbol;Acc:MGI:894703]) HSP 1 Score: 290.426 bits (742), Expect = 1.727e-82 Identity = 271/1017 (26.65%), Postives = 438/1017 (43.07%), Query Frame = 3
Query: 369 EGVPKFIQQPKSMYYVSKSHPAVITCIAQPVSHVNIFCADKQYSYMNEEVS------ATGLKVIKMDNEGRLAVKGNRWKFSLEVQHKDVIEWFS--EYRCHCEAWNQIEQLQKVKKVESSSAVIYDSYINKDFKTVPKNQKVSVRGSVKLSCIPPDAKPPAEIHWVKNGEKITGKSHPQFEINEYGELLLSNIRLTDSGNYSCVASSFGLERHAT-AQILVFEVGQWSDWSEWTGICPNICSKGSNCPKVCSTSRQQRVRYCNQIK--NQKANCIGSEIEYKRCDLICDPN-LWTFWSEWSKCSGNPCKKERTRQCTT---NNCGKASS---VEIDNCTLAECGGFVASFINSNKKYPESSTSIYITHDVAMYIGLFVAVSVFLMVVAIIFCLIRRRVIGFSPNRVWRYSTTANGIQMFYPDXXXXXXXXXXXXXXXXXXDINQPSLYRSIVLPNSLPFLPSNQSDASSNSAYTDVGNDITYIQRNHLPSLPMIATPLLSSMKPTLKIRPSYSDSKVSSTLYPQMGLVKHVSTLPIPVSSSLSDHYQELGNTDNETSDQSVTEPCLPYNFNGENMIWATIDSSGGRISLALSDINLTCPPNSFAPGISEPIFLATCNSEQDLPNLSANETLLSPVVVCGPTNVIAFKPFILNIPHCAYNTDSGNWAISVLTSYSPLKQKPYWQKYLDLDAEDKDSPPGYAQLAKDRLFLITNQLQRFCVVGSSYRNKRATKVLRIA----AYCTGLDRRHADEQIVVRLYLIPDIAECISKVHNFETNRLGARLVTNQKQFFCEDEAGNITVVISDLA-MDWQASSANNYQEIPFKDVWHSP--TLHCSFNFIKRLINANSSELKISVNSLDFNWFCTLSIYQTNSHHNKQTVLLSTPNGSSHTSISATSTQFSNYSAGGSQSFPYFVDDCSKTNFESVFKLPEQTKIKLCKLLDSLTPLDNDWRQLARHLSITRSLQFFSNKLSSTEILLDLWEAQNHSRKSLNNLIDILRKMGRLDCVAILEKD 3344
E +P F+ +P+ Y V K+ P + C A P + + C + ++ N+ V+ ATGL+V ++ +EV + V E F +Y C C AW+ +S A I +Y+ K+F P ++V + V L C PP+ P AE+ W+KN + I F + L++ RL+D+ NY+CVA + +R +T A ++V+ G WS W+EW+ C N C +G Q+R R C N A C G + C +C + WT WS+WS CS C R+R+C N G+ S ++ NCT C ++ + DVA+Y GL VAV V + V+ + ++ RR + S G F+P N P L P++ P L +A + Y ++ +PM +PLL + P+LKI+ Y+ S + S GL L + + + + + S ++ L + + + T GGR+SL + ++L P + G ++L +E LP ++T+LSP V CGPT ++ +P +L +PHCA +G+W + T + +W++ + LD E ++P Y QL ++ +QL + +G SY ++ A K L++A A CT L + +R+Y + D + +V E LG LV K +D N+ + + D+ W++ YQEIPF VW+ LHC+F + + + K+ V ++ I+Q + T L TP GS SA + +Q PY FK+P + K+C LD+ NDWR LA+ LS+ R L +F+ K S T ++LDLWEA+ LN+L L +MG+ + + + D
Sbjct: 45 EQLPYFLLEPQDAYIV-KNKPVELHCRAFPATQIYFKC-NGEWVSQNDHVTQESLDEATGLRVREVQ---------------IEVSRQQVEELFGLEDYWCQCVAWS------SSGTTKSRRAYIRIAYLRKNFDQEPLAKEVPLDHEVLLQCRPPEGVPVAEVEWLKNEDVIDPAQDTNFLLTIDHNLIIRQARLSDTANYTCVAKNIVAKRRSTTATVIVYVNGGWSSWAEWS-PCSNRCGRG----------WQKRTRTCTNPAPLNGGAFCEGQAFQKTACTTVCPVDGAWTEWSKWSACS-TECAHWRSRECMAPPPQNGGRDCSGTLLDSKNCTDGLC-----------------VLTLETSGDVALYAGLVVAVFVVVAVLMAVGVIVYRRNCRDFDTDITDSSAALTG--GFHP-------------VNFKTARPNNPQLLH----PSAPPDL----------TASAGIYRGPVYALQDSADKIPMTNSPLLDPL-PSLKIK-VYNSSTIGSG----SGLADGADLLGVLPPGTYPGDFSRDTHFLHLRSASLGSQHLLGLPRDPSSSVSGTFGCLGGRLSLPGTGVSLLVPNGAIPQGKFYDLYLHINKAESTLPLSEGSQTVLSPSVTCGPTGLLLCRPVVLTVPHCA-EVIAGDWIFQLKTQ----AHQGHWEEVVTLDEETLNTP-CYCQLEAKSCHILLDQLGTYVFMGESY-SRSAVKRLQLAIFAPALCTSL-------EYSLRVYCLEDTPVALKEVLELERT-LGGYLVEEPKPLLFKDSYHNLRLSLHDIPHAHWRSKLLAKYQEIPFYHVWNGSQRALHCTFTLERHSLASTEFTCKVCVRQVEGEG----QIFQLH------TTLAETPAGSLDALCSAPGNAIT------TQLGPY------------AFKIPLSIRQKICSSLDAPNSRGNDWRLLAQKLSMDRYLNYFATKASPTGVILDLWEARQQDDGDLNSLASALEEMGKSEMLVAMATD 931
BLAST of Unc-5 netrin receptor B vs. Ensembl Mouse
Match: Unc5c (unc-5 netrin receptor C [Source:MGI Symbol;Acc:MGI:1095412]) HSP 1 Score: 285.804 bits (730), Expect = 8.115e-81 Identity = 259/1014 (25.54%), Postives = 436/1014 (43.00%), Query Frame = 3
Query: 369 EGVPKFIQQPKSMYYVSKSHPAVITCIAQPVSHVNIFCADKQYSYMNEEVSATGLKVIKMDNEGRLAVKGNRWKFSLEVQHKDVIEWFS--EYRCHCEAWNQIEQLQKVKKVESSSAVIYDSYINKDFKTVPKNQKVSVRGSVKLSCIPPDAKPPAEIHWVKNGEKITGKSHPQFEINEYGELLLSNIRLTDSGNYSCVASSFGLERHA-TAQILVFEVGQWSDWSEWTGICPNICSKGSNCPKVCSTSRQQRVRYCNQIK--NQKANCIGSEIEYKRCDLICDPN-LWTFWSEWSKCSGNPCKKERTRQCTT---NNCGK---ASSVEIDNCTLAECGGFVASFINSNKKYPESSTSIYITHDVAMYIGLFVAVSVFLMVVAIIFCLIRRRVIGFSPNRVWRYSTTANGIQMFYPDXXXXXXXXXXXXXXXXXXDI-NQPSLYRSIVLPNSLPFLPSNQSDASSNSAYTDVGNDITYIQRNHLPSLPMIATPLLSSMKPTLKIRPSYSDSKVSSTLYPQMGLVKHVSTLPIPVSSSLSDHYQELGNTDNETSDQSVTEPCLPYNFNGENMIWATIDSSGGRISLALSDINLTCPPNSFAPGISEPIFLATCNSEQDLPNLSANETLLSPVVVCGPTNVIAFKPFILNIPHCAYNTDSGNWAISVLTSYSPLKQKPYWQKYLD--LDAEDKDSPPGYAQLAKDRLFLITNQLQRFCVVGSSYRNKRATKVLRIAAY----CTGLDRRHADEQIVVRLYLIPDIAECISKVHNFETNRLGARLVTNQKQFFCEDEAGNITVVISDLAMD-WQASSANNYQEIPFKDVWHSP--TLHCSFNFIKRLINANSSELKISVNSLDFNWFCTLSIYQTNSHHNKQTVLLSTPNGSSHTSISATSTQFSNYSAGGSQSFPYFVDDCSKTNFESVFKLPEQTKIKLCKLLDSLTPLDNDWRQLARHLSITRSLQFFSNKLSSTEILLDLWEAQNHSRKSLNNLIDILRKMGRLDCVAILEKD 3344
E +P F+ +P+ Y V K+ P + C A P + + C + ++ + + V ++D L V+ + S+E+ + V E F +Y C C AW+ +S A + +Y+ K F+ P ++VS+ V L C PP+ P AE+ W+KN + I F I L++ RL+D+ NY+CVA + +R + TA ++V+ G WS W+EW+ +C + C +G Q+R R C N A C G ++ C +C + WT WS+WS C G C R R+CT N GK ++ NCT C + P+S DVA+Y+G+ +AV+V L + ++ + R+ + + S G Q + + D+ + ++YR V A DV + I PM +P+L + P LKI+ S V+ PQ L + S L ++ SL ++ E N N++ + C + T +S GG + + S ++L P + G +++ E P + ++TLL+PVV CGP + +P IL + HCA + + +W I LK + ++ D + E+ + P Y QL + ++T L + +VG S K A K L++A + C+ L+ +R+Y + D + + +V E ++G +L+ K + N+ + I D+A W++ YQEIPF +W LHC+F + +N K+ V ++ I+Q N +++ + P ++I+ + S F +P + KLC LD+ +DWR LA L++ R L +F+ K S T ++LDLWEAQN +L+ L +L +MGR + V L +
Sbjct: 59 EPLPHFLIEPEEAYIV-KNKPVNLYCKASPATQIYFKC-NSEWVHQKDHVVDE-----RVDETSGLIVR----EVSIEISRQQVEELFGPEDYWCQCVAWS------SAGTTKSRKAYVRIAYLRKTFEQEPLGKEVSLEQEVLLQCRPPEGIPVAEVEWLKNEDIIDPAEDRNFYITIDHNLIIKQARLSDTANYTCVAKNIVAKRKSTTATVIVYVNGGWSTWTEWS-VCNSRCGRG----------YQKRTRTCTNPAPLNGGAFCEGQSVQKIACTTLCPVDGRWTSWSKWSTC-GTECTHWRRRECTAPAPKNGGKDCDGLVLQSKNCTDGLC----------MQAAPDSD-------DVALYVGIVIAVTVCLAITVVVALFVYRKNHRDFESDIIDSSALNGGFQ-------PVNIKAARQDLLAVPPDLTSAAAMYRGPVY------------------ALHDVSDKI-----------PMTNSPILDPL-PNLKIKVYNSSGAVT----PQDDLAEFSSKLSPQMTQSLLEN--EALNLKNQSLARQTDPSCTAF---------GTFNSLGGHLIIPNSGVSLLIPAGAIPQGRVYEMYVTVHRKENMRPPMEDSQTLLTPVVSCGPPGALLTRPVILTLHHCA-DPSTEDWKIQ-------LKNQAVQGQWEDVVVVGEENFTTPCYIQLDAEACHILTENLSTYALVGQS-TTKAAAKRLKLAIFGPLCCSSLEYS-------IRVYCLDDTQDALKEVLQLE-RQMGGQLLEEPKALHFKGSIHNLRLSIHDIAHSLWKSKLLAKYQEIPFYHIWSGSQRNLHCTFTLERLSLNTVELVCKLCVRQVEGEG----QIFQLNCTVSEEPTGIDLPLLDPASTITTVTG-------------------------PSAFSIPLPIRQKLCSSLDAPQTRGHDWRMLAHKLNLDRYLNYFATKSSPTGVILDLWEAQNFPDGNLSMLAAVLEEMGRHETVVSLAAE 928
BLAST of Unc-5 netrin receptor B vs. UniProt/SwissProt
Match: sp|Q8JGT4|UN5BA_XENLA (Netrin receptor UNC5B-a OS=Xenopus laevis OX=8355 GN=unc5b-a PE=2 SV=1) HSP 1 Score: 308.531 bits (789), Expect = 6.505e-88 Identity = 267/1013 (26.36%), Postives = 442/1013 (43.63%), Query Frame = 3
Query: 369 EGVPKFIQQPKSMYYVSKSHPAVITCIAQPVSHVNIFCADKQYSYMNEEVSATGLKVIKMDNEGRLAVKGNRWKFSLEVQHKDVIEWFS--EYRCHCEAWNQIEQLQKVKKVESSSAVIYDSYINKDFKTVPKNQKVSVRGSVKLSCIPPDAKPPAEIHWVKNGEKITGKSHPQFEINEYGELLLSNIRLTDSGNYSCVASSFGLERHA-TAQILVFEVGQWSDWSEWTGICPNICSKGSNCPKVCSTSRQQRVRYCNQIK--NQKANCIGSEIEYKRCDLICDPN-LWTFWSEWSKCSGNPCKKERTRQC---TTNNCGKASS---VEIDNCTLAECGGFVASFINSNKKYPESSTSIYITHDVAMYIGLFVAV-SVFLMVVAIIFCLIRRRVIGFSPNRVWRYSTTANGIQMFYPDXXXXXXXXXXXXXXXXXXDINQPSLYRSIVLPNSLPFLPSNQSDASSNSAYTDVGNDITYIQRNHLPSLPMIATPLLSSMKPTLKIRPSYSDSKVSSTLYPQMGLVKHVSTLPI-PVSSSLSDHYQELGNTDNETSDQSVTEPCLPYNFNGENMIWATIDSSGGRISLALSDINLTCPPNSFAPGISEPIFLATCNSEQDLPNLSANETLLSPVVVCGPTNVIAFKPFILNIPHCAYNTDSGNWAISVLTSYSPLKQKPYWQKYLDLDAEDKDSPPGYAQLAKDRLFLITNQLQRFCVVGSSYRNKRATKVLRIAAY----CTGLDRRHADEQIVVRLYLIPDIAECISKVHNFETNRLGARLVTNQKQFFCEDEAGNITVVISDLAMD-WQASSANNYQEIPFKDVWHSP--TLHCSFNFIKRLINANSSELKISVNSLDFNWFCTLSIYQTNSHHNKQTVLLSTPNGSSHTSISATSTQFSNYSAGGSQSFPYFVDDCSKTNFESVFKLPEQTKIKLCKLLDSLTPLDNDWRQLARHLSITRSLQFFSNKLSSTEILLDLWEAQNHSRKSLNNLIDILRKMGRLDCVAILEKD 3344
E +P F+ +P+ Y V K+ P + C A P + + C + ++ N+ ++ ++D+ L V+ + +EV + V E F +Y C C AW+ +S + + +Y+ K+F P ++V++ L C PP+ PPAE+ W+KN E I F I L++ RL+D+ NY+CV+ + +R + TA ++VF G WS W+EW S C C Q+R R C N C G + + C+ +C + WT WS+WS CS C R+R+C T N GK S ++ NCT C + + ES T DVA+Y GL VA+ V ++++A+ + RR F + + G F+P +N +++ NS P+ Q D ++N+ GN Y ++ +PM +PLL + P LKI+ Y+ S V S+ G+ + L P + SD+ N + +T P + N + T S GGR++ + ++L P + G ++L E + +T+LSP++ CGPT ++ KP IL +PHCA + ++ +W + + T + W++ + L+ E ++ P Y QL + +QL + VG SY ++ A K L++A + CT L+ +++Y + D + + +V E LG LV K +D N+ + I D+ W++ YQEIPF +W TLHC+F + + A KI V ++ I+Q HT + F + + S + FK+P + K+C LD+ NDWR LA+ L + R L +F+ K S T ++LDLWEA + LN L L +MG+ + + ++ D
Sbjct: 48 ESLPHFLLEPEDAYIV-KNKPVELVCKANPATQIYFKC-NGEWVNQNDHITKE-----RVDDVTGLVVR----EVQIEVSRQQVEELFGLEDYWCQCVAWS------SAGTTKSKRSYVRIAYLRKNFDQEPLGKEVALEQEALLQCRPPEGVPPAEVEWLKNEEIIDPTKDTNFLITIDHNLIIKQARLSDTANYTCVSKNIVAKRRSTTATVIVFVNGGWSSWTEW-----------SPCNNRCGHGWQKRTRTCTNPAPLNGGTMCEGQQYQKFACNTMCPVDGGWTEWSKWSACS-TECTHWRSRECNAPTPKNGGKDCSGMLLDSKNCTDGLCMQNKRVLGETKSRLLES------TGDVALYAGLVVAIFIVIILLMAVGIVVYRRNCREFDTDITDSSAALTGG---FHP--------------------VN----FKTSRHDNSQLIHPAMQPDLTANAGIYR-GN--MYALQDSADKIPMTNSPLLDPL-PNLKIK-VYNSSTVGSS----PGIHDGNNLLGTKPTGTYPSDNNIMNARNKNMSMQHLLTLP-----RDSSNSVTGTFGSLGGRLTFPNTGVSLLIPQGAIPQGKYYEMYLMINKRENTVLPSEGTQTILSPIITCGPTGLLLCKPVILTVPHCA-DINTSDWILQLKTQ----SHQGNWEEVVTLNEETLNT-PCYCQLESHSCHTLLDQLGTYAFVGESY-SRSAIKRLQLAIFAPMLCTSLEYN-------LKVYCVEDTPDALKEVLELEKT-LGGYLVEEPKLLMFKDSYHNLRLSIHDIPHSLWRSKLMAKYQEIPFYHIWSGSQRTLHCTFTLERYSLAATELTCKICVRQVEGEG----QIFQL------------------HTLLEENVKSFDPFCSQAENSVTTHLG-------PYAFKIPFSIRQKICNSLDAPNSRGNDWRLLAQKLCMDRYLNYFATKASPTGVILDLWEALHQDDGDLNTLASALEEMGKSEMMLVMATD 940
BLAST of Unc-5 netrin receptor B vs. UniProt/SwissProt
Match: sp|Q8IZJ1|UNC5B_HUMAN (Netrin receptor UNC5B OS=Homo sapiens OX=9606 GN=UNC5B PE=1 SV=2) HSP 1 Score: 307.76 bits (787), Expect = 1.313e-87 Identity = 286/1046 (27.34%), Postives = 452/1046 (43.21%), Query Frame = 3
Query: 300 WDSKENHEVDSKKDLVLPSE---KHLEGVPKFIQQPKSMYYVSKSHPAVITCIAQPVSHVNIFCADKQYSYMNEEVSATGLKVIKMDNEGRLAVKGNRWKFSLEVQHKDVIEWFS--EYRCHCEAWNQIEQLQKVKKVESSSAVIYDSYINKDFKTVPKNQKVSVRGSVKLSCIPPDAKPPAEIHWVKNGEKITGKSHPQFEINEYGELLLSNIRLTDSGNYSCVASSFGLERHAT-AQILVFEVGQWSDWSEWTGICPNICSKGSNCPKVCSTSRQQRVRYCNQIK--NQKANCIGSEIEYKRCDLICDPN-LWTFWSEWSKCSGNPCKKERTRQCTT---NNCGKASS---VEIDNCTLAECGGFVASFINSNKKYPESSTSIYITHDVAMYIGLFVAVSVF---LMVVAIIFCLIRRRVIGFSPNRVWRYSTTANGIQMFYPDXXXXXXXXXXXXXXXXXXDINQPSLYRSIVLPNSLPFLPSNQSDASSNSAYTDVGNDITYIQRNHLPSLPMIATPLLSSMKPTLKIRPSYSDSKVSSTLYPQMGLVKHVSTLPI-PVSSSLSD-----HYQELGNTDNETSDQSVTEPCLPYNFNGENMIWATIDSSGGRISLALSDINLTCPPNSFAPGISEPIFLATCNSEQDLPNLSANETLLSPVVVCGPTNVIAFKPFILNIPHCAYNTDSGNWAISVLTSYSPLKQKPYWQKYLDLDAEDKDSPPGYAQLAKDRLFLITNQLQRFCVVGSSYRNKRATKVLRIA----AYCTGLDRRHADEQIVVRLYLIPDIAECISKVHNFETNRLGARLVTNQKQFFCEDEAGNITVVISDLA-MDWQASSANNYQEIPFKDVWHS--PTLHCSFNFIKRLINANSSELKISVNSLDFNWFCTLSIYQTNSHHNKQTVLLSTPNGSSHTSISATSTQFSNYSAGGSQSFPYFVDDCSKTNFESVFKLPEQTKIKLCKLLDSLTPLDNDWRQLARHLSITRSLQFFSNKLSSTEILLDLWEAQNHSRKSLNNLIDILRKMGRLDCVAILEKD 3344
WD + + VLP E +P F+Q+P+ Y V K+ P + C A P + + C + ++ N+ V+ GL D L V+ + +EV + V E F +Y C C AW+ +S A + +Y+ K+F P ++V + V L C PP+ P AE+ W+KN + I F + L++ RL+D+ NY+CVA + +R +T A ++V+ G WS W+EW+ C N C +G Q+R R C N A C G + C IC + WT WS+WS CS C R+R+C N G+ S ++ NCT C + + N E+S D A+Y GL VA+ V LM V ++ + RR F + + G F+P +N +++ N PS D ++++ + Y ++ +PM +PLL + P+LK++ YS S S GL L + P + SD H+ L + + S Q + P P + + T GGR+S+ + ++L P + G ++L +E LP +T+LSP V CGPT ++ +P IL +PHCA + +W + T + +W++ + LD E ++P Y QL ++ +QL + G SY ++ A K L++A A CT L + +R+Y + D + +V E LG LV K +D N+ + + DL W++ YQEIPF +W LHC+F + + + KI V ++ I+Q + T L TP GS T SA + + +Q PY FK+P + K+C LD+ NDWR LA+ LS+ R L +F+ K S T ++LDLWEA LN+L L +MG+ + + + D
Sbjct: 19 WDPRLSQAGTDSGSEVLPDSFPSAPAEPLPYFLQEPQDAYIV-KNKPVELRCRAFPATQIYFKC-NGEWVSQNDHVTQEGL-----DEATGLRVR----EVQIEVSRQQVEELFGLEDYWCQCVAWS------SAGTTKSRRAYVRIAYLRKNFDQEPLGKEVPLDHEVLLQCRPPEGVPVAEVEWLKNEDVIDPTQDTNFLLTIDHNLIIRQARLSDTANYTCVAKNIVAKRRSTTATVIVYVNGGWSSWAEWS-PCSNRCGRG----------WQKRTRTCTNPAPLNGGAFCEGQAFQKTACTTICPVDGAWTEWSKWSACS-TECAHWRSRECMAPPPQNGGRDCSGTLLDSKNCTDGLCMQNKKTLSDPNSHLLEASG------DAALYAGLVVAIFVVVAILMAVGVV--VYRRNCRDFDTDITDSSAALTGG---FHP--------------------VN----FKTARPSNPQLLHPSVPPDLTASAG---IYRGPVYALQDSTDKIPMTNSPLLDPL-PSLKVK-VYSSSTTGSG----PGLADGADLLGVLPPGTYPSDFARDTHFLHL-RSASLGSQQLLGLPRDP-----GSSVSGTFGCLGGRLSIPGTGVSLLVPNGAIPQGKFYEMYLLINKAESTLPLSEGTQTVLSPSVTCGPTGLLLCRPVILTMPHCA-EVSARDWIFQLKTQ----AHQGHWEEVVTLDEETLNTP-CYCQLEPRACHILLDQLGTYVFTGESY-SRSAVKRLQLAVFAPALCTSL-------EYSLRVYCLEDTPVALKEVLELERT-LGGYLVEEPKPLMFKDSYHNLRLSLHDLPHAHWRSKLLAKYQEIPFYHIWSGSQKALHCTFTLERHSLASTELTCKICVRQVEGEG----QIFQLH------TTLAETPAGSLDTLCSAPGSTVT------TQLGPY------------AFKIPLSIRQKICNSLDAPNSRGNDWRMLAQKLSMDRYLNYFATKASPTGVILDLWEALQQDDGDLNSLASALEEMGKSEMLVAVATD 942
BLAST of Unc-5 netrin receptor B vs. UniProt/SwissProt
Match: sp|C5IAW9|UN5BB_XENLA (Netrin receptor UNC5B-b OS=Xenopus laevis OX=8355 GN=unc5b-b PE=1 SV=1) HSP 1 Score: 307.375 bits (786), Expect = 1.795e-87 Identity = 271/1014 (26.73%), Postives = 445/1014 (43.89%), Query Frame = 3
Query: 369 EGVPKFIQQPKSMYYVSKSHPAVITCIAQPVSHVNIFCADKQYSYMNEEVSATGLKVIKMDNEGRLAVKGNRWKFSLEVQHKDVIEWFS--EYRCHCEAWNQIEQLQKVKKVESSSAVIYDSYINKDFKTVPKNQKVSVRGSVKLSCIPPDAKPPAEIHWVKNGEKITGKSHPQFEINEYGELLLSNIRLTDSGNYSCVASSFGLERHAT-AQILVFEVGQWSDWSEWTGICPNICSKGSNCPKVCSTSRQQRVRYCNQIK--NQKANCIGSEIEYKRCDLICDPNL-WTFWSEWSKCSGNPCKKERTRQC---TTNNCGKASS---VEIDNCTLAECGGFVASFINSNKKYPESSTSIYI--THDVAMYIGLFVAVSVFLMVVAIIFCLIRRRVIGFSPNRVWRYSTTANGIQMFYPDXXXXXXXXXXXXXXXXXXDINQPSLYRSIVLPNSLPFLPSNQSDASSNSAYTDVGNDITYIQRNHLPSLPMIATPLLSSMKPTLKIRPSYSDSKVSSTLYPQMGLVKHVSTLPI-PVSSSLSDHYQELGNTDNETSDQSVTEPCLPYNFNGENMIWATIDSSGGRISLALSDINLTCPPNSFAPGISEPIFLATCNSEQDLPNLSANETLLSPVVVCGPTNVIAFKPFILNIPHCAYNTDSGNWAISVLTSYSPLKQKPYWQKYLDLDAEDKDSPPGYAQLAKDRLFLITNQLQRFCVVGSSYRNKRATKVLRIAAY----CTGLDRRHADEQIVVRLYLIPDIAECISKVHNFETNRLGARLVTNQKQFFCEDEAGNITVVISDLAMD-WQASSANNYQEIPFKDVWHSP--TLHCSFNFIKRLINANSSELKISVNSLDFNWFCTLSIYQTNSHHNKQTVLLSTPNGSSHTSISATSTQFSNYSAGGSQSFPYFVDDCSKTNFESVFKLPEQTKIKLCKLLDSLTPLDNDWRQLARHLSITRSLQFFSNKLSSTEILLDLWEAQNHSRKSLNNLIDILRKMGRLDCVAILEKD 3344
E +P F+ +P+ Y V K+ + C A P + + C + ++ N+ ++ ++D+ L V+ + +EV + V E F ++ C C AW+ +S + + +Y+ K+F P ++V++ L C PP+ PPAE+ W+KN E I F I L++ RL+D+ NY+CVA + +R +T A ++VF G WS W+EW S C C Q+R R C N C G + + C+ +C + WT WS+WS CS C R+R+C T N GK S ++ NCT C NK+ + S + T DVA+Y GL VA+ + ++++ + ++ RR + S G F+P +N +++ NS P+ Q D ++N+ + Y ++ +PM +PLL + P LKI+ Y+ S V S+ G+ L P + SD N N + T+ L + N + T S GGR++ + ++L P + G ++L E + +T+LSP++ CGPT ++ KP IL +PHCA T S +W + + T + W++ + L+ E ++P Y QL ++ +QL + VG SY ++ A K L++A + CT L+ +++Y + D + + +V E LG L+ K +D N+ + I D+ W++ YQEIPF VW TLHC+F + + A KI V ++ I+Q H + + + S SH S T TQ Y+ FK+P + K+C LD+ NDWR LA+ L + R L +F+ K S T ++LDLWEA + LN L L +MG+ + + ++ D
Sbjct: 48 ESLPHFLLEPEDAYIV-KNKAVELVCKANPATQIYFKC-NGEWVNQNDHITKE-----RVDDVTGLVVR----EVQIEVSRQQVEELFGLEDFWCQCVAWS------SAGTTKSKRSYVRIAYLRKNFDQEPLGKEVALEQEALLQCRPPEGVPPAEVEWLKNEEIIDSTKDTNFLITIDHNLIIKQARLSDTANYTCVAKNIVAKRRSTTATVIVFVNGGWSSWTEW-----------SPCNNRCGHGWQKRTRTCTNPAPLNGGTMCEGQQYQKFACNTMCPVDGGWTEWSKWSACS-TECTHWRSRECNAPTPKNGGKDCSGMLLDSKNCTDGLC--------MQNKRVLGETKSHLLESTGDVALYAGLVVAIFIIIILLMAVGIVVYRRNCREFDTDITDSSAALTG--GFHP--------------------VN----FKTSRHDNSHLIHPAMQPDLTANAG---IYRGHMYALQDSADKIPMTNSPLLDPL-PNLKIK-VYNSSTVGSS----PGIHDGNDLLGAKPTGTYPSD------NIMNARNKNMSTQHLLTLPRDSSNSVTGTFGSLGGRLTFPNTGVSLLIPQGAIPQGKYYEMYLMINKRENTVLPSEGTQTILSPIITCGPTGLLLCKPVILTVPHCADITTS-DWILQLKTQ----SHQGNWEEVVTLNEETLNTP-CYCQLESHSCHILLDQLGTYAFVGESY-SRSAIKRLQLAIFAPMLCTSLEYN-------LKVYCVEDTPDALKEVLELEKT-LGGYLIEEPKPLMFKDSYHNLRLSIHDIPHSLWRSKLLAKYQEIPFYHVWSGSQRTLHCTFTLERYSLAATELTCKICVRQVEGEG----QIFQL--HTSLEENVKSFDPFCSHAENSVT-TQLGPYA----------------------FKIPFLIRQKICNSLDAPNSRGNDWRLLAQKLCMDRYLNYFATKASPTGVILDLWEALHQDDGDLNTLASALEEMGKSEMMLVMATD 939
BLAST of Unc-5 netrin receptor B vs. UniProt/SwissProt
Match: sp|Q8K1S3|UNC5B_MOUSE (Netrin receptor UNC5B OS=Mus musculus OX=10090 GN=Unc5b PE=1 SV=1) HSP 1 Score: 295.049 bits (754), Expect = 4.008e-83 Identity = 274/1017 (26.94%), Postives = 442/1017 (43.46%), Query Frame = 3
Query: 369 EGVPKFIQQPKSMYYVSKSHPAVITCIAQPVSHVNIFCADKQYSYMNEEVS------ATGLKVIKMDNEGRLAVKGNRWKFSLEVQHKDVIEWFS--EYRCHCEAWNQIEQLQKVKKVESSSAVIYDSYINKDFKTVPKNQKVSVRGSVKLSCIPPDAKPPAEIHWVKNGEKITGKSHPQFEINEYGELLLSNIRLTDSGNYSCVASSFGLERHAT-AQILVFEVGQWSDWSEWTGICPNICSKGSNCPKVCSTSRQQRVRYCNQIK--NQKANCIGSEIEYKRCDLICDPN-LWTFWSEWSKCSGNPCKKERTRQCTT---NNCGKASS---VEIDNCTLAECGGFVASFINSNKKYPESSTSIYITHDVAMYIGLFVAVSVFLMVVAIIFCLIRRRVIGFSPNRVWRYSTTANGIQMFYPDXXXXXXXXXXXXXXXXXXDINQPSLYRSIVLPNSLPFLPSNQSDASSNSAYTDVGNDITYIQRNHLPSLPMIATPLLSSMKPTLKIRPSYSDSKVSSTLYPQMGLVKHVSTLPIPVSSSLSDHYQELGNTDNETSDQSVTEPCLPYNFNGENMIWATIDSSGGRISLALSDINLTCPPNSFAPGISEPIFLATCNSEQDLPNLSANETLLSPVVVCGPTNVIAFKPFILNIPHCAYNTDSGNWAISVLTSYSPLKQKPYWQKYLDLDAEDKDSPPGYAQLAKDRLFLITNQLQRFCVVGSSYRNKRATKVLRIA----AYCTGLDRRHADEQIVVRLYLIPDIAECISKVHNFETNRLGARLVTNQKQFFCEDEAGNITVVISDLA-MDWQASSANNYQEIPFKDVWHSP--TLHCSFNFIKRLINANSSELKISVNSLDFNWFCTLSIYQTNSHHNKQTVLLSTPNGSSHTSISATSTQFSNYSAGGSQSFPYFVDDCSKTNFESVFKLPEQTKIKLCKLLDSLTPLDNDWRQLARHLSITRSLQFFSNKLSSTEILLDLWEAQNHSRKSLNNLIDILRKMGRLDCVAILEKD 3344
E +P F+ +P+ Y V K+ P + C A P + + C + ++ N+ V+ ATGL+V ++ +EV + V E F +Y C C AW+ +S A I +Y+ K+F P ++V + V L C PP+ P AE+ W+KN + I F + L++ RL+D+ NY+CVA + +R +T A ++V+ G WS W+EW+ C N C +G Q+R R C N A C G + C +C + WT WS+WS CS C R+R+C N G+ S ++ NCT C +N K +P + + DVA+Y GL VAV V + V+ + ++ RR + S G F+P N P L P++ P L +A + Y ++ +PM +PLL + P+LKI+ Y+ S + S GL L + + + + + S ++ L + + + T GGR+SL + ++L P + G ++L +E LP ++T+LSP V CGPT ++ +P +L +PHCA +G+W + T + +W++ + LD E ++P Y QL ++ +QL + +G SY ++ A K L++A A CT L + +R+Y + D + +V E LG LV K +D N+ + + D+ W++ YQEIPF VW+ LHC+F + + + K+ V ++ I+Q + T L TP GS SA + +Q PY FK+P + K+C LD+ NDWR LA+ LS+ R L +F+ K S T ++LDLWEA+ LN+L L +MG+ + + + D
Sbjct: 45 EQLPYFLLEPQDAYIV-KNKPVELHCRAFPATQIYFKC-NGEWVSQNDHVTQESLDEATGLRVREVQ---------------IEVSRQQVEELFGLEDYWCQCVAWS------SSGTTKSRRAYIRIAYLRKNFDQEPLAKEVPLDHEVLLQCRPPEGVPVAEVEWLKNEDVIDPAQDTNFLLTIDHNLIIRQARLSDTANYTCVAKNIVAKRRSTTATVIVYVNGGWSSWAEWS-PCSNRCGRG----------WQKRTRTCTNPAPLNGGAFCEGQAFQKTACTTVCPVDGAWTEWSKWSACS-TECAHWRSRECMAPPPQNGGRDCSGTLLDSKNCTDGLCV-LNQRTLNDPKSHP-----LETSGDVALYAGLVVAVFVVVAVLMAVGVIVYRRNCRDFDTDITDSSAALTG--GFHP-------------VNFKTARPNNPQLLH----PSAPPDL----------TASAGIYRGPVYALQDSADKIPMTNSPLLDPL-PSLKIK-VYNSSTIGSG----SGLADGADLLGVLPPGTYPGDFSRDTHFLHLRSASLGSQHLLGLPRDPSSSVSGTFGCLGGRLSLPGTGVSLLVPNGAIPQGKFYDLYLHINKAESTLPLSEGSQTVLSPSVTCGPTGLLLCRPVVLTVPHCA-EVIAGDWIFQLKTQ----AHQGHWEEVVTLDEETLNTP-CYCQLEAKSCHILLDQLGTYVFMGESY-SRSAVKRLQLAIFAPALCTSL-------EYSLRVYCLEDTPVALKEVLELERT-LGGYLVEEPKPLLFKDSYHNLRLSLHDIPHAHWRSKLLAKYQEIPFYHVWNGSQRALHCTFTLERHSLASTEFTCKVCVRQVEGEG----QIFQLH------TTLAETPAGSLDALCSAPGNAIT------TQLGPY------------AFKIPLSIRQKICSSLDAPNSRGNDWRLLAQKLSMDRYLNYFATKASPTGVILDLWEARQQDDGDLNSLASALEEMGKSEMLVAMATD 942
BLAST of Unc-5 netrin receptor B vs. UniProt/SwissProt
Match: sp|O08722|UNC5B_RAT (Netrin receptor UNC5B OS=Rattus norvegicus OX=10116 GN=Unc5b PE=1 SV=1) HSP 1 Score: 294.664 bits (753), Expect = 5.745e-83 Identity = 272/1019 (26.69%), Postives = 442/1019 (43.38%), Query Frame = 3
Query: 369 EGVPKFIQQPKSMYYVSKSHPAVITCIAQPVSHVNIFCADK---QYSYMNEEV--SATGLKVIKMDNEGRLAVKGNRWKFSLEVQHKDVIEWFS--EYRCHCEAWNQIEQLQKVKKVESSSAVIYDSYINKDFKTVPKNQKVSVRGSVKLSCIPPDAKPPAEIHWVKNGEKITGKSHPQFEINEYGELLLSNIRLTDSGNYSCVASSFGLERHAT-AQILVFEVGQWSDWSEWTGICPNICSKGSNCPKVCSTSRQQRVRYCNQIK--NQKANCIGSEIEYKRCDLICDPN-LWTFWSEWSKCSGNPCKKERTRQCTT---NNCGKASS---VEIDNCTLAECGGFVASFINSNKKYPESSTSIYITHDVAMYIGLFVAVSVFL---MVVAIIFCLIRRRVIGFSPNRVWRYSTTANGIQMFYPDXXXXXXXXXXXXXXXXXXDINQPSLYRSIVLPNSLPFLPSNQSDASSNSAYTDVGNDITYIQRNHLPSLPMIATPLLSSMKPTLKIRPSYSDSKVSSTLYPQMGLVKHVSTLPIPVSSSLSDHYQELGNTDNETSDQSVTEPCLPYNFNGENMIWATIDSSGGRISLALSDINLTCPPNSFAPGISEPIFLATCNSEQDLPNLSANETLLSPVVVCGPTNVIAFKPFILNIPHCAYNTDSGNWAISVLTSYSPLKQKPYWQKYLDLDAEDKDSPPGYAQLAKDRLFLITNQLQRFCVVGSSYRNKRATKVLRIA----AYCTGLDRRHADEQIVVRLYLIPDIAECISKVHNFETNRLGARLVTNQKQFFCEDEAGNITVVISDLA-MDWQASSANNYQEIPFKDVWHS--PTLHCSFNFIKRLINANSSELKISVNSLDFNWFCTLSIYQTNSHHNKQTVLLSTPNGSSHTSISATSTQFSNYSAGGSQSFPYFVDDCSKTNFESVFKLPEQTKIKLCKLLDSLTPLDNDWRQLARHLSITRSLQFFSNKLSSTEILLDLWEAQNHSRKSLNNLIDILRKMGRLDCVAILEKD 3344
E +P F+ +P+ Y V K+ P + C A P + + C + Q ++ +E ATGL++ ++ +EV + V E F +Y C C AW+ +S A I +Y+ K+F P ++V + V L C PP+ P AE+ W+KN + I F + L++ RL+D+ NY+CVA + +R +T A ++V+ G WS W+EW+ C N C +G Q+R R C N A C G + C +C + WT WS+WS CS C R+R+C N G+ S ++ NCT C +N S + + DVA+Y GL VAV V L M V +I + RR F + + G F+P +N +++ N PS D ++++ + Y ++ +PM +PLL + P+LKI+ Y S + S GL L + + + + + S ++ L + + + T GGR+++ + ++L P + G ++L +E LP ++T+LSP V CGPT ++ +P +L +PHCA +G+W + T + +W++ + LD E ++P Y QL ++ +QL + G SY ++ A K L++A A CT L + +R+Y + D + +V E LG LV K +D N+ + + D+ W++ YQEIPF VW+ LHC+F + + + K+ V ++ I+Q + T L TP GS SA +A +Q PY FK+P + K+C LD+ NDWR LA+ LS+ R L +F+ K S T ++LDLWEA+ LN+L L +MG+ + + + D
Sbjct: 45 EQLPHFLLEPEDAYIV-KNKPVELHCRAFPATQIYFKCNGEWVSQKGHVTQESLDEATGLRIREVQ---------------IEVSRQQVEELFGLEDYWCQCVAWS------SSGTTKSRRAYIRIAYLRKNFDQEPLAKEVPLDHEVLLQCRPPEGVPVAEVEWLKNEDVIDPAQDTNFLLTIDHNLIIRQARLSDTANYTCVAKNIVAKRRSTTATVIVYVNGGWSSWAEWS-PCSNRCGRG----------WQKRTRTCTNPAPLNGGAFCEGQACQKTACTTVCPVDGAWTEWSKWSACS-TECAHWRSRECMAPPPQNGGRDCSGTLLDSKNCTDGLC------VLNQRTLNDPKSRPLEPSGDVALYAGLVVAVFVVLAVLMAVGVI--VYRRNCRDFDTDITDSSAALTGG---FHP--------------------VN----FKTARPSNPQLLHPSAPPDLTASAG---IYRGPVYALQDSADKIPMTNSPLLDPL-PSLKIK-VYDSSTIGSG----AGLADGADLLGVLPPGTYPGDFSRDTHFLHLRSASLGSQHLLGLPRDPSSSVSGTFGCLGGRLTIPGTGVSLLVPNGAIPQGKFYDLYLRINKTESTLPLSEGSQTVLSPSVTCGPTGLLLCRPVVLTVPHCA-EVIAGDWIFQLKTQ----AHQGHWEEVVTLDEETLNTP-CYCQLEAKSCHILLDQLGTYVFTGESY-SRSAVKRLQLAIFAPALCTSL-------EYSLRVYCLEDTPAALKEVLELERT-LGGYLVEEPKTLLFKDSYHNLRLSLHDIPHAHWRSKLLAKYQEIPFYHVWNGSQKALHCTFTLERHSLASTEFTCKVCVRQVEGEG----QIFQLH------TTLAETPAGSLDALCSAPG------NAATTQLGPY------------AFKIPLSIRQKICNSLDAPNSRGNDWRLLAQKLSMDRYLNYFATKASPTGVILDLWEARQQDDGDLNSLASALEEMGKSEMLVAMTTD 942
BLAST of Unc-5 netrin receptor B vs. TrEMBL
Match: E1CHK7 (Uncoordinated 5 OS=Dugesia japonica OX=6161 GN=Djunc5A PE=2 SV=1) HSP 1 Score: 518.464 bits (1334), Expect = 1.288e-162 Identity = 348/1056 (32.95%), Postives = 545/1056 (51.61%), Query Frame = 3
Query: 297 DWDSKENHEVDSKKDLVLPSEKHLEGVPKFIQQPKSMYYVSKSHPAVITCIAQPVSHVNIFCADKQYSYMNEEVSATGLKVIKMDNEGRLAVKGNRWKFSLEVQHKDVIEWFSEYRCHCEAWNQIEQLQKVKKVESSSAVIYDSYINKDFKTVPKNQKVSVRGSVKLSCIPPDAKPPAEIHWVKNGEKITGKSHPQFEINEYGELLLSNIRLTDSGNYSCVASSFGLERHATAQILVFEVG-QWSDWSEWTGICPNICSKGSNCP-KVCSTSRQQRVRYC--NQIKNQKANCIGSEIEYKRCDLICDP--NLWTFWSEWSKCSGNPCKKERTRQCTTNNCGKASSVEIDNCTLAECGGFVASFINSNKKYPESSTSIYITHDVAMYIGLFVAVSVFLMVVAIIFCLIRRR-VIGFSPNRVWRYSTTANGIQMFYPDXXXXXXXXXXXXXXXXXXDINQPSLYRSIVLPNSLPFLPSNQSDASSNSAYTDVGNDITYIQRNHLPSLPMIATPLLSSM----KPTLKIRPSYSDSKVSSTLYPQMGLV-KHVSTLP--IPVSSSLSDHYQELGNTDNETSDQSVTEPC-----------------LPYNFNGENMIWATIDSSGGRISLALSDINLTCPPNSFAPGISEPIFLATCNSEQDLPNLSANETLLSPVVVCGPTNVIAFKPFILNIPHCAYNTDSGNWAISVLTS-YSPLKQKPYWQKYLDLDAEDKDSPPGYAQLAKDRLFLITNQLQRFCVVG--SSYRNKRATKVLRIAAYCTGLDRRHADEQIVVRLYLIPDIAECISKVHNFETNRLGARLVTNQKQFFCEDEAGNITVVISDLAMDWQASSANNYQEIPFKDVWHSPTLHCSFNFIKRLINANSSELKISVNSLD---FNWFCTLSIYQTNSHHNKQTVLLSTPNGSSHTSISATSTQFSNYSAGGSQSFPYFVDDCSKTNFESVFKLPEQTKIKLCKLLDSLTPLDNDWRQLARHLSITRSLQFFSNKLSSTEILLDLWEAQNHSRKSLNNLIDILRKMGRLDCVAILEKDLIQ 3353
+W EVD KKDLV P+EKH +G+PKF+ +P YYV+K+HPA+I C+A+PVSHVNIFCADKQ+SYMN E S +GL VIKM++ + KGNRWKFSLEV++KDV+EWFSEY+C+CEAWNQI + K KKV SS+A+I +SY DFKT PK+Q++ ++L C PP++KP +++ W+KN E IT + P I+E L++ + +DSGNY+CVA S G+ + + +++ + WS W++W CP IC + C ++CS+S +QR+RYC +IK + +C G E + CD C+ + W WS W+ C + R R+C NC + NC+ C S I + MY+GLF+ +S+ +++ II CLI ++ I P R +S NG+ Y +K+ K NS FL +N D + I I+ ++ L +AT LLS + P ++ + + +V +Y ++ K T P P+ +S+ + T E +++ P LP + + + W TI ++GGR+ L S I+LT P + G SE +FLA C ++P + E LLSPV++CGP + K IL IPHCA N +W I VL++ + + P W++ + ++ YAQL LI +QLQ C+ G S + + LRI A+ L ++ ++R++LIPD E I V E +L +L+ N K+F G+I + + DL++ W+ S+N Q S++FI RL ++ + E+ + +D + C ++I Q + N+ V + ++ SI S + + SQ+ ++D ++VF+L T+ +L LLD W+ LA H+ + +L +FS K+S ++ LLDLWEA+ ++ +LI+ILR +GR DC I+E+D+++
Sbjct: 33 EWPDNSESEVDGKKDLVQPNEKHYDGIPKFLVEPHPFYYVNKTHPALIICVAEPVSHVNIFCADKQFSYMNTERSESGLIVIKMNHLNQPDSKGNRWKFSLEVKYKDVLEWFSEYKCYCEAWNQITMINKDKKVHSSAALIQESYFQNDFKTTPKSQELREGNKLELQCTPPESKPNSKVTWLKNDELITQSNFPLIIIDESKRLIIEQVLKSDSGNYTCVAQSQGVVKKSKPAVIIITMKYNWSPWAKW-NTCPEICKMETKCQNEICSSSHRQRIRYCLNEEIKVEDKHCKGESNEKESCDKACEKEESKWNSWSFWTTICFPNCSQTRVRRCEFGNCFGPKQ-QSRNCSQIICQRADPSL-------------ILESQSTTMYLGLFITISILFIIILIILCLITQKGYISLLPRRGMVFSNHNNGMTKIYTNKSSK----------------------------NSEKFLLNN-----------DQKSTIVTIKNHNAQDL--VATSLLSEIPNNYSPVYEMHSNNNRDQVLPAIYSDYPMISKSQYTYPSTAPLLNSILSPERSYNETSEEDQKANLSSPLYQELSIGRGSCGLLSNYLPPDMELDTIAWGTITTAGGRLCLPQSGISLTIPRGAIHHGNSEEMFLAVCRDHTNIPVIDMMEMLLSPVILCGPPQIQLLKSVILTIPHCA-NIQCSDWNIRVLSARFQNSQIPPLWKELSTIRPVNRSDSNIYAQLDSTSAHLIIDQLQMICITGCLSPLSDSSVSIRLRILAFSLPLS---SELDHIIRVHLIPDTKEAIENVIASEL-KLNGQLLDNSKKFTFSSSGGDIALCLDDLSLGWRCHSSNKMQTF-------------SYSFIWRLNHSQNQEIHFLLEHVDPTRTGFSCNITIQQIDLPQNQVIVRVIKERSPNNRSIIPISLDSRSNNREFSQA---YLDP-----LQTVFRLSFTTRQQLWPLLDP------SWQTLANHMLLNGNLNYFSEKMSPSDALLDLWEARCRDEGAIADLINILRVIGRNDCAMIVEQDILK 1000
BLAST of Unc-5 netrin receptor B vs. TrEMBL
Match: A0A210QTQ7 (Netrin receptor UNC5C OS=Mizuhopecten yessoensis OX=6573 GN=KP79_PYT06250 PE=4 SV=1) HSP 1 Score: 378.252 bits (970), Expect = 2.316e-110 Identity = 294/1031 (28.52%), Postives = 479/1031 (46.46%), Query Frame = 3
Query: 354 SEKHLEGVPKFIQQPKSMYYVSKSHPAVITCIAQPVSHVNIFCAD-KQYSYMNEEVSATGL--KVIKMDNEGRLAVKGNRWKFSLEVQHKDVIEWFSE--YRCHCEAWNQIEQLQKVKKVESSSAVIYDSYINKDFKTVPKNQKVSVRGSVKLSCIPPDAKPPAEIHWVKNGEKITGKSHPQFEINEYGELLLSNIRLTDSGNYSCVASSFGLERHATAQIL-VFEVGQWSDWSEWTGICPNICSKGSNCPKVCSTSRQQRVRYCNQIK--NQKANCIGSEIEYKRCDLICD-PNLWTFWSEWSKCSGNPCKKERTRQCT----TNNCGKASSVEID--NCTLAEC------GGFVASFINSNKKYPESSTSIYITHDVAMYIGLFVAVSVFLMVVAIIFCLIRRRVIGFSPNRVWRYSTTANGIQMFYPDXXXXXXXXXXXXXXXXXXDINQPSLYRSIVLPNSLPFLPSNQSDASSNSAYTDVGNDITYIQRNHLPSLPMIATPLLSSMKPTLKIRPSYSD-SKVSSTLYPQMGLVKHVSTLPIPVSSSLSDHYQE-----LGNTDNETSDQSVTEPCLPYNFNGENMIWATIDSSGGRISLALSDINLTCPPNSFAPGISEPIFLATCNSEQDLPNLSANETLLSPVVVCGPTNVIAFKPFILNIPHCAYNTDSGNWAISVLTSYSPLKQKPYWQKYLDLDAEDKDSPPGYAQLAKDRLFLITNQLQRFCVVGSSYRNKRATKVLRIAAYCTGLDRRHADEQIVVRLYLIPDIAECISKVHNFETNRLGARLVTNQKQFFCEDEAGNITVVISDLAMDWQASSANNYQEIPFKDVWHSP--TLHCSFNFIKRLINANSSELKISVNSLDFNWFCTLSIYQTNSHHNKQTVLLST----PNGSSHTSISATSTQFSNYSAGGSQSFPYFVD-DCSKTNFESVFKLPEQTKIKLCKLLDSLTPLDNDWRQLARHLSITRSLQFFSNKLSSTEILLDLWEAQNHSRKSLNNLIDILRKMGRLDCVAILEKD 3344
S+ L G P FI++P+ YY+ K+ P I C A + CA QY + EE + L KVI LEV +V ++F E + C C A N ++ KK++S ++ + + + F+ P + + ++ +L+C+PP+ KP E+ W+KNGE+I K I+ G LL +R++D+GNY+C A + +R + + +L V+ G WS WS+W S C C Q+R R C N A C+G + C IC W+ WS WS CS + C R R C N G S ++D NCT C G + P + + ++A+YIG+ V++ VV IF + ++ + R + + +N + +K KN + + + P L +++V+ +N ++ S S + N+ NH+ S+ I + P++ R S +K TL+ + + + +P + + N + S QS+ LP N + E + W T + GGR+ L+ S + LT P + G +E +F+A C ++D P LS ++T++SPV++ GP KP IL++ HCA N G W +S+ TS +P + P W K + L E ++P YAQL + ++T LQR+ ++G + + K+LR+AA+ + +R+Y++ D + + V E + G RL+ KQ +D N+ + I +L W++ A NYQEIPF+ +W LHCSF+ L + + K+S C + +YQ N+Q + +S + S T S + S + S F V D NF +LP + +LC LLD NDWR LA+ L++ R +QFF+ K S TE +LDLWEA++ ++ +L++I R MGRLD ++LE+D
Sbjct: 23 SDPRLIGSPMFIKEPEPYYYIVKNRPINIHCKAVSAVQIKFRCAGVDQYHEITEEYFDSNLNKKVISS---------------RLEVTRDEVKDYFGEGGFWCECYATNSLQDTDNGKKIKSRKGMVEIAMMRRWFEHEPMSLRAALDTDAQLTCLPPEGKPRPEVFWLKNGEEIDIKKTNNI-ISSEGNLLFPQVRISDTGNYTCGARNVVAKRISQSAVLTVYVNGSWSTWSQW-----------STCSVKCGRGSQKRYRACTNPTPLNGGAPCVGETSQKTECTAICPVRGQWSMWSSWSTCSPD-CLHHRRRSCDDPPPENGGGYCSGNDLDSTNCTGGMCRERTLYGDLRGPVKTATTVGPNAGSG-----NIALYIGICVSI-----VVLAIFVI----LVALAIRRKSQNANNSNQPPLTDEEKKAHKNGNGVVSVP--------PDLTQTVVIVQH-----NNMNNGISRSPSLEAPNN------NHVNSVENIYDK--PDISPSMDSRLSGGTLTKNGKTLFVEPTFMNNRPQEKLPYEKDVPPPVPLGPRPPIQNNNVMDSRQSMMSVQLPSNIDMEAVAWTTFNHQGGRLVLSDSGVALTVPEGAIKKGHTEELFIAVCRDDKDRPKLSDHQTVISPVILVGPVKHDMLKPVILSVQHCA-NMRQGGWMLSLCTSDTPTDEPPRWHKIVTLGQETINTPI-YAQLDPNHCHIMTEYLQRYALIGEAVHGGKPIKILRLAAFAPMMP---PSMDFSIRVYVVEDTQDALESVIQ-EERKFGGRLLDKPKQIPFQDGGHNLCLTIEELTPGWRSKLAANYQEIPFQHIWSGTQNNLHCSFS----LELVDRAYHKVS---------CKIQVYQKAILSNRQVLNISNNFKEKSTSCSTPSSTLKGRSSTVTTNSSSGFSSMVTLDPQGQNF----RLPTHIRTRLCMLLDPPNARGNDWRMLAQALTVDRYVQFFATKGSPTEHILDLWEARHREETAVTDLMNIFRVMGRLDAASVLEED 967
BLAST of Unc-5 netrin receptor B vs. TrEMBL
Match: A0A1S3JPZ4 (netrin receptor UNC5C-like isoform X3 OS=Lingula unguis OX=7574 GN=LOC106174972 PE=4 SV=1) HSP 1 Score: 369.392 bits (947), Expect = 4.737e-107 Identity = 291/1029 (28.28%), Postives = 475/1029 (46.16%), Query Frame = 3
Query: 378 PKFIQQPKSMYYVSKSHPAVITCIAQPVSHVNIFCAD-----KQYSYMNEEVSATGLKVIKMDNEGRLAVKGNRWKFSLEVQHKDVIEWFS--EYRCHCEAWNQIEQLQKV--------KKVESSSAVIYDSYINKDFKTVPKNQKVSVRGSVKLSCIPPDAKPPAEIHWVKNGEKITGKSHPQFEINEYGELLLSNIRLTDSGNYSCVASSFGLERHA-TAQILVFEVGQWSDWSEWTGICPNICSKGSNCPKVCSTSRQQRVRYCNQIK--NQKANCIGSEIEYKRCDLICDPNL-WTFWSEWSKCSGNPCKKERTRQCTT---NNCGK---ASSVEIDNCTLAECGGFVASFINSNKKYPESSTSIYITHDVAMYIGLFVAVSVFLMVVAIIFCLIRRRVIGFSPNRVWRYSTTANGIQMFYPDXXXXXXXXXXXXXXXXXXDINQPSLYRSIVLPNSLPFLPSNQSDASSNSAYTDVGNDITYIQRNHLPSLPMIATPLLSSMKPTLKIRPSYSDSKVSSTLYPQM-GLVKHVSTLPIPV--------SSSLSDHYQELGNTDNETSDQSVTEPCLPYNFNGENMIWATIDSSGGRISLALSDINLTCPPNSFAPGISEPIFLATCNSEQDLPNLSANETLLSPVVVCGPTNVIAFKPFILNIPHCAYNTDSGNWAISVLTSYSPLKQKPYWQKYLDLDAEDKDSPPGYAQLAKDRLFLITNQLQRFCVVGSSYRNKRATKVLRIAAYCTGLDRRHADEQIVVRLYLIPDIAECISKVHNFETNRLGARLVTNQKQFFCEDEAGNITVVISDLAMDWQASSANNYQEIPFKDVW--HSPTLHCSFNFIKRLINANSSELKISVNSLDFNWFCTLSIYQTNSHHNK---QTVLLSTPNGSSHTSISATSTQFSNYSAGGSQSFPYFVDDCSKTNFESVFKLPEQTKIKLCKLLDSLTPLDNDWRQLARHLSITRSLQFFSNKLSSTEILLDLWEAQNHSRKSLNNLIDILRKMGRLDCVAILEKDL 3347
P F+Q+P+ Y+ KS P ITC A + CA+ K++ + TG V++ S+EV + V E+F Y C C AW +I + V S ++ ++I K F+ P + V + V+L C+PP PP E+ W+K+G+ I K F I+ G L++S RL+D GN++C A + R + +A+++V+ G WS WS+W S+C C Q R R C+ N + C G + C +C + W+ W+ WS C+ + CK R R+C N GK ++ + I NCT GG F S+ + D+A+Y+G+ +AV V ++ II +IRR+ D+ + + +P+ ++V P+ L + ++S Y D NH+ ++ I P+L+ T + S K S LY Q+ G K ST + + SS+ Q +TDN ++ QSVT LP N + E + W I +GG +++ + ++++ P + + G +E IF+A C ++D P LS +T+LSP+++ GP + KP I++ HCA + G W + V S + + P W K+L E+ + P Y Q+ + ++T+QL R+ ++G S + A K LR+AA+ + + +R+Y++ D + + V E +LGA L+ KQ +D N+ + I +LA W++ NYQEIPF+ +W + LHCSF+ ++ L+ +V+ C + +YQ + N+ Q V T ++ + S+ G S +D K F+LP Q K KLC LD NDWR LA+ L + R + FF++K S TE +LDLWEA++ +L +L++ LR M R D A+LEK+L
Sbjct: 50 PIFLQEPEPHNYIVKSKPVTITCQAINAVDITFRCAEEWVPLKRHVRADFTHPETGEAVLQA---------------SVEVTRQAVEEYFGIDGYWCECNAWTEIPSPDRPWTGDNPPPAHVSSRRGLVQVAFIRKRFEREPISTSVELEKPVQLHCLPPTGVPPPEVFWLKDGQVINDKEETNFIISNEGNLIISQARLSDQGNFTCGAINVAATRKSESAELIVYVKGAWSTWSQW-----------SDCDSKCGKGFQSRSRTCSNPAPLNNGSPCPGDWEQKVPCTTVCPVDGGWSTWASWSTCNED-CKHFRRRRCDNPPPQNNGKHCESTDLNITNCT----GGLCREFPGSDVYAERTEKPGQDVKDIALYVGVSLAVLVLATIIVIIIFMIRRK------------------------DQRQFDMDLGERSLPQYDDEDKKPAKNGAMVQPD----LTQTIAPVRTHSLY-----DQPPPNNNHIDAMEKI--PMLNGH--THPVEDSPIIDKKSKHLYIQLPGEEKTDSTEKLTLQKSKASLKSSTSGSRPQSEYDTDN-SNRQSVTSNLLPSNIDVEALAWGNITHAGGMLTIPETGVSVSIPEGAISKGNTEEIFIAVCRDDKDRPKLSDKQTILSPILLLGPQGLALHKPVIVSFQHCA-SQKHGLWVMRVYGSGTAYDEPPAW-KHLVTFGEETLNTPIYCQVDTNCCHMMTDQLCRYALIGESMQGTAAMKRLRLAAFAPAV---ASSIDYSIRVYVVEDTQDAVEGVIQLE-KKLGAALLDRPKQILFQDGGNNLCLTIEELAPGWRSKLTANYQEIPFRHIWSGNQNNLHCSFSL------EHTDGLQQTVS-------CKIGVYQKSILGNRAVLQIVSNLTEKVIPSPTVPGKPRASTTVSSSGCSSM-VTLDQAQK-----AFRLPSQIKTKLCAYLDPPNSRGNDWRMLAQALCVDRYINFFASKPSPTEHILDLWEARHREETALTDLMNTLRVMDRFDAAAVLEKEL 984
BLAST of Unc-5 netrin receptor B vs. TrEMBL
Match: D1LX77 (Netrin receptor unc5-like protein OS=Saccoglossus kowalevskii OX=10224 PE=2 SV=1) HSP 1 Score: 366.311 bits (939), Expect = 2.953e-105 Identity = 300/1089 (27.55%), Postives = 481/1089 (44.17%), Query Frame = 3
Query: 369 EGVPKFIQQPKSMYYVSKSHPAVITCIAQPVSHVNIFCADKQYSYMNEEVSATGLKVIKMDNEGRLAVKGNRWKFSLEVQHKDVIEWF---SEYRCHCEAWNQIEQLQKVKKVESSSAVIYDSYINKDFKTVPKNQKVSVRGSVKLSCIPPDAKPPAEIHWVKNGEKITGKSHPQFEINEYGELLLSNIRLTDSGNYSCVASSFGLERHA-TAQILVFEVGQWSDWSEWTGICPNICSKGSNCPKVCSTSRQQRVRYCNQIK--NQKANCIGSEIEYKRCDLICDPN-LWTFWSEWSKCSGNPCKKERTRQCTT---NNCGK---ASSVEIDNCTLAEC---GGFVASFINSNKKYPESSTSIYITHDVAMYIGLFVAVSVFLMVVAIIFCLIRRRVI----------------GFSPNRVWRYSTTANGIQM----FYPDXXXXXXXXXXXXXXXXXXDINQPSLYRSIVLPNSLPF--LPSNQSDASSNSAYTDVGNDITYIQRNHLPSLPMIATPLLSSMKPTLKIRPSYSDSKVSSTLYPQMGLVKHVSTLPIPVSSSLSDHYQELGNTD--NETSDQSV-----TEPC---------------------------------------LPYNFNGENMIWATIDSSGGRISLALSDINLTCPPNSFAPGISEPIFLATCNSEQDLPNLSAN-ETLLSPVVVCGPTNVIAFKPFILNIPHCAYNTDSGNWAISVLTSYSPLKQKPYWQKYLDLDAEDKDSPPGYAQLAKDRLFLITNQLQRFCVVGSSYRNKRATKVLRIAAYCTGLDRRHADEQIVVRLYLIPDIAECISKVHNFETNRLGARLVTNQKQFFCEDEAGNITVVISDLAMDWQASSANNYQEIPFKDVWHSP--TLHCSFNFIKRLINANSSELKISVNSLDFNWFCTLSIYQTNSHHNKQTVLLSTPNGSSHTSISATSTQFSN---YSAG---GSQSFPYFVDDCSKTNFE---SVFKLPEQTKIKLCKLLDSLTPLDNDWRQLARHLSITRSLQFFSNKLSSTEILLDLWEAQNHSRKSLNNLIDILRKMGRLDCVAILEKDL 3347
E +P+FI +P+ Y V K+ +TC+A P H+ C + ++ + + L GN K + V ++ IE F +Y C C AW + V+S A I S++ K F+ P + + + ++ C PP+ P +I+W K+G +I + + I L+++ RL D+GNY+CVA + +R + A++ V+ G WS WS WTG C + C KG Q+R R C N A C GS + C +C + WT W+EWS CS C R+R C+ N GK +E NCT C G A S+ P+ +A+Y+GL VA VF++V I LI R+V G PN++ + + M PD N + D++ L ++ P P +P+N+S S + + T N ++ ++ P S + R S+ VSS P K ++ LP+ +L + + TD ++DQS+ T+ C LP + + + W + GGR+++ + +++ + A G +E I++A C E+D P + A ET+LSPV++CGPT++ KP ++ PHCA+ + NW S+ T S + P W+K + + E ++P Y QL + FL+ ++L RF +VG S A K+L++AA+ L R AD I R+Y++ D E + V E RLG L+ KQ D ++ + I ++ W++ + NYQEIP+ +W LHC+F L + + C +++YQ + KQ + + T+++ T QF Y G S CS + +VF++P T+ KLC LD NDWR LAR L + R + FF+ K S TE +LDLWEA+ ++L++L+ I ++MGR D V ++EKD+
Sbjct: 51 EPIPEFIVEPEDGYIV-KNADITLTCVAAPAMHIYFKC------------NGDWVRGKHLVQQETLDEAGNAQKEASIVLTRNEIESFFGDEDYWCQCVAWGE------GGSVKSRKATIVISFLKKAFEREPLGANIEIESAFQMMCRPPEGNPLPDIYWEKDGRQIDVQEDRNYIITTDASLIINQARLADTGNYTCVAQNMASKRKSDVAKVNVYVNGAWSTWSAWTG-CDSRCGKGI----------QRRTRTCTNPAPLNGGAPCPGSSSQTSPCTTLCPVDGSWTSWNEWSNCSPE-CNHIRSRTCSNPRPQNSGKLCKGLDMESRNCTDGLCKLVGIEGAEHQESDLTEPKVKKGS--GDGIALYVGLIVACVVFMLVCVFIVYLIHRKVRQAGVYIDINASDMTLPGACPNQIKGHKIGQDNAHMAMLSIQPDVTQSTCQLRNQNLMMRNGDMDTTKLV--MISPPVPPIYNIPNNKSKMSDSMTLS-----ATTPSENKYETIQPLSCPECSVTPSQISPRSSF----VSSCYSPVHSPDKELNVLPLD-DEALKEKLDIIRETDLIGSSTDQSIKMAVETDDCNSEKSFGTLKSLSDSSSRPMSMYDSDNLGNSMCSIASTTLPTHIDPRCIAWGMMGHRGGRLTVPDTGVSVLIAEGALAKGQTEEIYIAVCREEKDRPKVKAGKETILSPVIMCGPTHLNFKKPVVVQFPHCAH-VEGCNWVSSIYTCDSHPDEPPNWEKVVTIGEETINTPL-YCQLDESECFLMVDRLSRFALVGESRPGHEACKILKLAAFAQPL-RSLADYNI--RVYVVDDTLEALEGVVQVE-QRLGGHLLDKPKQLEFVDSGASLCLTIDNIMTGWRSKLSANYQEIPYYHIWSGNMNALHCAFTL---------ERLDRQIQKI----HCRITVYQVSGGKEKQCLQI-------LTNVNETKAQFPPEMLYGLGRSRSSTVTTNSTSGCSSMTVDPPSTVFRIPRPTRNKLCICLDRPMKKGNDWRLLARKLKVDRYINFFATKPSPTEHILDLWEARCRGERALSDLLRIFKEMGRNDVVDLIEKDV 1068
BLAST of Unc-5 netrin receptor B vs. TrEMBL
Match: A0A1S3JQG5 (netrin receptor UNC5C-like isoform X1 OS=Lingula unguis OX=7574 GN=LOC106174972 PE=4 SV=1) HSP 1 Score: 364.77 bits (935), Expect = 4.032e-105 Identity = 291/1045 (27.85%), Postives = 475/1045 (45.45%), Query Frame = 3
Query: 378 PKFIQQPKSMYYVSKSHPAVITCIAQPVSHVNIFCAD-----KQYSYMNEEVSATGLKVIKMDNEGRLAVKGNRWKFSLEVQHKDVIEWFS--EYRCHCEAWNQIEQLQKV--------KKVESSSAVIYDSYINKDFKTVPKNQKVSVRGSVKLSCIPPDAKPPAEIHWVKNGEKITGKSHPQFEINEYGELLLSNIRLTDSGNYSCVASSFGLERHA-TAQILVFEVGQWSDWSEWTGICPNICSKGSNCPKVCSTSRQQRVRYCNQIK--NQKANCIGSEIEYKRCDLICDPNL-----------------WTFWSEWSKCSGNPCKKERTRQCTT---NNCGK---ASSVEIDNCTLAECGGFVASFINSNKKYPESSTSIYITHDVAMYIGLFVAVSVFLMVVAIIFCLIRRRVIGFSPNRVWRYSTTANGIQMFYPDXXXXXXXXXXXXXXXXXXDINQPSLYRSIVLPNSLPFLPSNQSDASSNSAYTDVGNDITYIQRNHLPSLPMIATPLLSSMKPTLKIRPSYSDSKVSSTLYPQM-GLVKHVSTLPIPV--------SSSLSDHYQELGNTDNETSDQSVTEPCLPYNFNGENMIWATIDSSGGRISLALSDINLTCPPNSFAPGISEPIFLATCNSEQDLPNLSANETLLSPVVVCGPTNVIAFKPFILNIPHCAYNTDSGNWAISVLTSYSPLKQKPYWQKYLDLDAEDKDSPPGYAQLAKDRLFLITNQLQRFCVVGSSYRNKRATKVLRIAAYCTGLDRRHADEQIVVRLYLIPDIAECISKVHNFETNRLGARLVTNQKQFFCEDEAGNITVVISDLAMDWQASSANNYQEIPFKDVW--HSPTLHCSFNFIKRLINANSSELKISVNSLDFNWFCTLSIYQTNSHHNK---QTVLLSTPNGSSHTSISATSTQFSNYSAGGSQSFPYFVDDCSKTNFESVFKLPEQTKIKLCKLLDSLTPLDNDWRQLARHLSITRSLQFFSNKLSSTEILLDLWEAQNHSRKSLNNLIDILRKMGRLDCVAILEKDL 3347
P F+Q+P+ Y+ KS P ITC A + CA+ K++ + TG V++ S+EV + V E+F Y C C AW +I + V S ++ ++I K F+ P + V + V+L C+PP PP E+ W+K+G+ I K F I+ G L++S RL+D GN++C A + R + +A+++V+ G WS WS+W S+C C Q R R C+ N + C G + C +C + W+ W+ WS C+ + CK R R+C N GK ++ + I NCT GG F S+ + D+A+Y+G+ +AV V ++ II +IRR+ D+ + + +P+ ++V P+ L + ++S Y D NH+ ++ I P+L+ T + S K S LY Q+ G K ST + + SS+ Q +TDN ++ QSVT LP N + E + W I +GG +++ + ++++ P + + G +E IF+A C ++D P LS +T+LSP+++ GP + KP I++ HCA + G W + V S + + P W K+L E+ + P Y Q+ + ++T+QL R+ ++G S + A K LR+AA+ + + +R+Y++ D + + V E +LGA L+ KQ +D N+ + I +LA W++ NYQEIPF+ +W + LHCSF+ ++ L+ +V+ C + +YQ + N+ Q V T ++ + S+ G S +D K F+LP Q K KLC LD NDWR LA+ L + R + FF++K S TE +LDLWEA++ +L +L++ LR M R D A+LEK+L
Sbjct: 50 PIFLQEPEPHNYIVKSKPVTITCQAINAVDITFRCAEEWVPLKRHVRADFTHPETGEAVLQA---------------SVEVTRQAVEEYFGIDGYWCECNAWTEIPSPDRPWTGDNPPPAHVSSRRGLVQVAFIRKRFEREPISTSVELEKPVQLHCLPPTGVPPPEVFWLKDGQVINDKEETNFIISNEGNLIISQARLSDQGNFTCGAINVAATRKSESAELIVYVKGAWSTWSQW-----------SDCDSKCGKGFQSRSRTCSNPAPLNNGSPCPGDWEQKVPCTTVCPVDYYHSSTVSSTLGWPVDGGWSTWASWSTCNED-CKHFRRRRCDNPPPQNNGKHCESTDLNITNCT----GGLCREFPGSDVYAERTEKPGQDVKDIALYVGVSLAVLVLATIIVIIIFMIRRK------------------------DQRQFDMDLGERSLPQYDDEDKKPAKNGAMVQPD----LTQTIAPVRTHSLY-----DQPPPNNNHIDAMEKI--PMLNGH--THPVEDSPIIDKKSKHLYIQLPGEEKTDSTEKLTLQKSKASLKSSTSGSRPQSEYDTDN-SNRQSVTSNLLPSNIDVEALAWGNITHAGGMLTIPETGVSVSIPEGAISKGNTEEIFIAVCRDDKDRPKLSDKQTILSPILLLGPQGLALHKPVIVSFQHCA-SQKHGLWVMRVYGSGTAYDEPPAW-KHLVTFGEETLNTPIYCQVDTNCCHMMTDQLCRYALIGESMQGTAAMKRLRLAAFAPAV---ASSIDYSIRVYVVEDTQDAVEGVIQLE-KKLGAALLDRPKQILFQDGGNNLCLTIEELAPGWRSKLTANYQEIPFRHIWSGNQNNLHCSFSL------EHTDGLQQTVS-------CKIGVYQKSILGNRAVLQIVSNLTEKVIPSPTVPGKPRASTTVSSSGCSSM-VTLDQAQK-----AFRLPSQIKTKLCAYLDPPNSRGNDWRMLAQALCVDRYINFFASKPSPTEHILDLWEARHREETALTDLMNTLRVMDRFDAAAVLEKEL 1000
BLAST of Unc-5 netrin receptor B vs. Ensembl Cavefish
Match: unc5b (unc-5 netrin receptor B [Source:NCBI gene;Acc:103042383]) HSP 1 Score: 287.345 bits (734), Expect = 2.017e-81 Identity = 274/1027 (26.68%), Postives = 435/1027 (42.36%), Query Frame = 3
Query: 369 EGVPKFIQQPKSMYYVSKSHPAVITCIAQPVSHVNIFCADKQYSYMNEEVSATGLKVIKMDNEGRLAVKGNRWKFSLEVQHKDVIEWFS--EYRCHCEAWNQIEQLQKVKKVESSSAVIYDSYINKDFKTVPKNQKVSVRGSVKLSCIPPDAKPPAEIHWVKNGEKITGKSHPQFEINEYGELLLSNIRLTDSGNYSCVASSF-GLERHATAQILVFEVGQWSDWSEWTGICPNICSKGSNCPKVCSTSRQQRVRYCNQIK--NQKANCIGSEIEYKRCDLICDPNL-WTFWSEWSKCSGNPCKKERTRQCTT---NNCGK---ASSVEIDNCTLAECGGFVASFINSNKKYPESSTSIYI--THDVAMYIGLFVAVSVFLMVVAIIFCLIRRRVIGFSPNRVWRYSTTANGIQMFYPDXXXXXXXXXXXXXXXXXXDINQPSLYRSIVLPNSLPFLPSNQSDASSNSAYTDVGNDITYIQRNHLPS---LPMIATPLLSSMKPTLKIRPSYSDSKVSSTLYPQM-----GLVKHVSTLPIPVSSSLSDHYQELGNTDNETSDQSVTEPCLPYNFNGENMIWATIDSSGGRISLALSDINLTCPPNSFAPGISEPIFLATCNSEQDLPNLSANETLLSPVVVCGPTNVIAFKPFILNIPHCAYNTDSGNWAISVLTSYSPLKQKPYWQKYLDLDAEDKDSPPGYAQLAKDRLFLITNQLQRFCVVGSSYRNKRATKVLRIAAY-----CTGLDRRHADEQIVVRLYLIPDIAECISKVHNFETNRLGARLVTNQKQFFCEDEAGNITVVISDLAMD-WQASSANNYQEIPFKDVWHSPT--LHCSFNFIKRLINANSSELKISVNSLDFNWFCTLSIYQTNSHHNKQTVLLSTPNGSSHTSISATSTQFSNYSAGG-----SQSFPYFVDDCSKTNFESVFKLPEQTKIKLCKLLDSLTPLDNDWRQLARHLSITRSLQFFSNKLSSTEILLDLWEAQNHSRKSLNNLIDILRKMGRLDCVAILEKD 3344
E +P+F +P+ + V K+ P ++C A P + + C + ++ N+ V+ L I L V+ + + V V E F +Y C C AW+ +S A + +Y+ K+F+ P ++V + V L C PP+ PPAE+ W+KN + I F + +L++ RL+D+ NY+CVA + R +TA ++V+ G WS W+EW S C C Q+R R C N A C G + C +C + WT W++WS C G C R+R+C N G+ S +E NCT C NKK T+ + VA+Y GL A+ + +++V + L RR + S+ F+P Y+ N PS D ++ SA T G + +Q++ L S +PM +PLL + P LKI+ Y S +SS P G + + T V S DHY G+T S + AT+ GGR+++ + ++L PP + G ++L E+ +T+LSPVV CGP+ ++ +P IL +PHCA + +W++++ T + W++ L + E+ S P Y Q+ + ++ QL + +VG S + A K L++A + C LD +R+Y I D + +V E + LG L+ + K +D N+ + I D+ W++ YQEIPF +W LHC+F+ + + + KI V ++ I+Q HT I T S AGG SQ PY F+LP + K+C LD+ + DWR LA L R L +F+ K S T +LLDLWEA + L +L L +MG+ + + ++ D
Sbjct: 48 EPLPEFQSEPEDAFIV-KNRPVKLSCKAAPATQIYFKC-NGEWVNQNDHVTRESLDQIT-----GLVVR----EVDISVSRTQVEELFGLEDYWCQCVAWS------SAGTTKSRRAYVRIAYLRKNFEQEPLGREVRLEQEVLLQCRPPEGIPPAEVEWLKNEDLIDPTQDSNFLMTVDHDLIIKQARLSDTANYTCVARNVVAKRRSSTATLIVYVSGGWSSWTEW-----------SECNARCGRGWQRRTRSCTNPAPLNGGAFCEGPPFQRVTCTTLCPVDGGWTEWAKWSAC-GTECTHWRSRECQAPPPRNGGRHCIGSIMESKNCTEGLCA--------RNKKISIEHTTHPLDSGAGVAVYAGLVGALLLCVILVLCVGILAYRRSCSHLHGDITDSSSALTA--AFHPGN------------------------YKPPRQDNPHLLHPSAPPDLTA-SAGTFRGPLFSSLQQSTLDSHHKIPMTNSPLLDPL-PGLKIK-VYDSSTMSSVELPAGPGSSDGEIMSLKT----VGSGTRDHY---GHTLPGEPGHSAS---------------ATLGCLGGRLAIPNTGVSLLVPPGTIPQGKFYEMYLIINKWEKTTLPSEGGQTVLSPVVSCGPSGMLLSRPVILTLPHCA-QLEPPDWSLTLKT-----QTNQAWEEVLTV-GEESLSSPCYLQVEEQNCHVLMEQLGTYGLVGQSVPPQPACKRLQLALFAPRAPCLSLD-------YSLRVYCIHDTPHALKEVLELERS-LGGVLLEDPKPLLFKDSYHNLRLSIHDIPHSHWRSKLLAKYQEIPFYHIWSGSQRPLHCTFSLERGSLAVSQLSCKICVRQVEGEG----QIFQL------------------HTDIQETLPPHSPLPAGGTCLPSSQVGPY------------AFRLPASIRQKICASLDAPSARGCDWRLLAHSLGFDRYLNYFATKPSPTGVLLDLWEACHQGDADLVSLATALEEMGKSEVLVVMTTD 937
BLAST of Unc-5 netrin receptor B vs. Ensembl Cavefish
Match: unc5b (unc-5 netrin receptor B [Source:NCBI gene;Acc:103042383]) HSP 1 Score: 286.96 bits (733), Expect = 2.488e-81 Identity = 272/1025 (26.54%), Postives = 433/1025 (42.24%), Query Frame = 3
Query: 369 EGVPKFIQQPKSMYYVSKSHPAVITCIAQPVSHVNIFCADKQYSYMNEEVSATGLKVIKMDNEGRLAVKGNRWKFSLEVQHKDVIEWFS--EYRCHCEAWNQIEQLQKVKKVESSSAVIYDSYINKDFKTVPKNQKVSVRGSVKLSCIPPDAKPPAEIHWVKNGEKITGKSHPQFEINEYGELLLSNIRLTDSGNYSCVASSF-GLERHATAQILVFEVGQWSDWSEWTGICPNICSKGSNCPKVCSTSRQQRVRYCNQIK--NQKANCIGSEIEYKRCDLICDPNL-WTFWSEWSKCSGNPCKKERTRQCTT---NNCGK---ASSVEIDNCTLAECGGFVASFINSNKKYPESSTSIYITHDVAMYIGLFVAVSVFLMVVAIIFCLIRRRVIGFSPNRVWRYSTTANGIQMFYPDXXXXXXXXXXXXXXXXXXDINQPSLYRSIVLPNSLPFLPSNQSDASSNSAYTDVGNDITYIQRNHLPS---LPMIATPLLSSMKPTLKIRPSYSDSKVSSTLYPQM-----GLVKHVSTLPIPVSSSLSDHYQELGNTDNETSDQSVTEPCLPYNFNGENMIWATIDSSGGRISLALSDINLTCPPNSFAPGISEPIFLATCNSEQDLPNLSANETLLSPVVVCGPTNVIAFKPFILNIPHCAYNTDSGNWAISVLTSYSPLKQKPYWQKYLDLDAEDKDSPPGYAQLAKDRLFLITNQLQRFCVVGSSYRNKRATKVLRIAAY-----CTGLDRRHADEQIVVRLYLIPDIAECISKVHNFETNRLGARLVTNQKQFFCEDEAGNITVVISDLAMD-WQASSANNYQEIPFKDVWHSPT--LHCSFNFIKRLINANSSELKISVNSLDFNWFCTLSIYQTNSHHNKQTVLLSTPNGSSHTSISATSTQFSNYSAGG-----SQSFPYFVDDCSKTNFESVFKLPEQTKIKLCKLLDSLTPLDNDWRQLARHLSITRSLQFFSNKLSSTEILLDLWEAQNHSRKSLNNLIDILRKMGRLDCVAILEKD 3344
E +P+F +P+ + V K+ P ++C A P + + C + ++ N+ V+ L I L V+ + + V V E F +Y C C AW+ +S A + +Y+ K+F+ P ++V + V L C PP+ PPAE+ W+KN + I F + +L++ RL+D+ NY+CVA + R +TA ++V+ G WS W+EW S C C Q+R R C N A C G + C +C + WT W++WS C G C R+R+C N G+ S +E NCT G A ++S VA+Y GL A+ + +++V + L RR + S+ F+P Y+ N PS D ++ SA T G + +Q++ L S +PM +PLL + P LKI+ Y S +SS P G + + T V S DHY G+T S + AT+ GGR+++ + ++L PP + G ++L E+ +T+LSPVV CGP+ ++ +P IL +PHCA + +W++++ T + W++ L + E+ S P Y Q+ + ++ QL + +VG S + A K L++A + C LD +R+Y I D + +V E + LG L+ + K +D N+ + I D+ W++ YQEIPF +W LHC+F+ + + + KI V ++ I+Q HT I T S AGG SQ PY F+LP + K+C LD+ + DWR LA L R L +F+ K S T +LLDLWEA + L +L L +MG+ + + ++ D
Sbjct: 48 EPLPEFQSEPEDAFIV-KNRPVKLSCKAAPATQIYFKC-NGEWVNQNDHVTRESLDQIT-----GLVVR----EVDISVSRTQVEELFGLEDYWCQCVAWS------SAGTTKSRRAYVRIAYLRKNFEQEPLGREVRLEQEVLLQCRPPEGIPPAEVEWLKNEDLIDPTQDSNFLMTVDHDLIIKQARLSDTANYTCVARNVVAKRRSSTATLIVYVSGGWSSWTEW-----------SECNARCGRGWQRRTRSCTNPAPLNGGAFCEGPPFQRVTCTTLCPVDGGWTEWAKWSAC-GTECTHWRSRECQAPPPRNGGRHCIGSIMESKNCT----EGLCARTLDSGA-------------GVAVYAGLVGALLLCVILVLCVGILAYRRSCSHLHGDITDSSSALTA--AFHPGN------------------------YKPPRQDNPHLLHPSAPPDLTA-SAGTFRGPLFSSLQQSTLDSHHKIPMTNSPLLDPL-PGLKIK-VYDSSTMSSVELPAGPGSSDGEIMSLKT----VGSGTRDHY---GHTLPGEPGHSAS---------------ATLGCLGGRLAIPNTGVSLLVPPGTIPQGKFYEMYLIINKWEKTTLPSEGGQTVLSPVVSCGPSGMLLSRPVILTLPHCA-QLEPPDWSLTLKT-----QTNQAWEEVLTV-GEESLSSPCYLQVEEQNCHVLMEQLGTYGLVGQSVPPQPACKRLQLALFAPRAPCLSLD-------YSLRVYCIHDTPHALKEVLELERS-LGGVLLEDPKPLLFKDSYHNLRLSIHDIPHSHWRSKLLAKYQEIPFYHIWSGSQRPLHCTFSLERGSLAVSQLSCKICVRQVEGEG----QIFQL------------------HTDIQETLPPHSPLPAGGTCLPSSQVGPY------------AFRLPASIRQKICASLDAPSARGCDWRLLAHSLGFDRYLNYFATKPSPTGVLLDLWEACHQGDADLVSLATALEEMGKSEVLVVMTTD 926
BLAST of Unc-5 netrin receptor B vs. Ensembl Cavefish
Match: unc5c (unc-5 netrin receptor C [Source:ZFIN;Acc:ZDB-GENE-030131-9196]) HSP 1 Score: 283.493 bits (724), Expect = 3.967e-80 Identity = 257/1003 (25.62%), Postives = 418/1003 (41.67%), Query Frame = 3
Query: 369 EGVPKFIQQPKSMYYVSKSHPAVITCIAQPVSHVNIFCADKQYSYMNEEVSATGLKVIKMDNEGRLAVKGNRWKFSLEVQHKDVIEWFS--EYRCHCEAWNQIEQLQKVKKVESSSAVIYDSYINKDFKTVPKNQKVSVRGSVKLSCIPPDAKPPAEIHWVKNGEKITGKSHPQFEINEYGELLLSNIRLTDSGNYSCVASSFGLERHA-TAQILVFEVGQWSDWSEWTGICPNICSKGSNCPKVCSTSRQQRVRYCNQIK--NQKANCIGSEIEYKRCDLICDPN-LWTFWSEWSKCSGNPCKKERTRQCTT---NNCGK---ASSVEIDNCTLAECGGFVASFINSNKKYPESSTSIYITHDVAMYIGLFVAVSVFLMVVAIIFCLIRRRVIGFSPNRVWRYSTTANGIQMFYPDXXXXXXXXXXXXXXXXXXDINQPSLYRSIVLPNSLPFLPSNQSDASSNSAYTDVGNDITYIQRNHLPSLPMIATPLLSSMKPTLKIRPSYSDSKVSSTLYPQMGLVKHVSTLPIPVSSSL--SDHYQELGNTDNETSDQSVTEPCLPYNFNGENMIWATIDSSGGRISLALSDINLTCPPNSFAPGISEPIFLATCNSEQDLPNLSANETLLSPVVVCGPTNVIAFKPFILNIPHCAYNTDSGNWAISVLTSYSPLKQKPYWQKYLDLDAEDKDSPPGYAQLAKDRLFLITNQLQRFCVVGSSYRNKRATKVLRIAAY----CTGLDRRHADEQIVVRLYLIPDIAECISKVHNFETNRLGARLVTNQKQFFCEDEAGNITVVISDLAMD-WQASSANNYQEIPFKDVWHSP--TLHCSFNFIKRLINANSSELKISVNSLDFNWFCTLSIYQTNSHHNKQTVLLSTPNGSSHTSISATSTQFSNYSAGGSQSFPYFVDDCSKTNFESVFKLPEQTKIKLCKLLDSLTPLDNDWRQLARHLSITRSLQFFSNKLSSTEILLDLWEAQNHSRKSLNNLIDILRKMGR 3314
E +P F+ +P+ Y V K+ P + C A P + + C + ++ + E ++D L V+ + S+E+ + V E F ++ C C AW+ +S A + +Y+ K F P ++VS+ V L C PP+ P AE+ W+KN E I F I L++ RL+D+ NY+CVA + +R + TA ++V+ G WS W+EW S C C Q+R R C N A C G I+ C+ +C + LWT WS+WS C G C R R+C+ N GK ++ NCT C S T DVA+Y+G+ +AV + L++ I+ + R+ + + S G Q SI + L + S+ + Y Y + +PM +PLL + P LKI+ S V+ PQ L S L + SL SD + + D S T + + +S GG + + S ++L P + G +++ E P++ +T+LSPVV CGP + +P I+ + HCA DS +W I + + Q+ W+ + + E+ + P Y Q+ ++ ++T L +C+VG S + TK L++A + CT L+ +R+Y + D + + +V E ++G +L+ K +D N+ + + D+ W++ YQE+ F+ VW LHC+F + S +L+ C L + Q I +T S S S + + + F++P + KLC LD+ NDWR LA L++ R L +F+ K S T ++LDLWEAQ+ +LN L +L +MGR
Sbjct: 55 EPLPHFLMEPEEAYIV-KNKPVNLYCKATPATQIYFKC-NSEWVHQKEHTVEE-----RVDETSGLVVR----EASIEITRQQVEELFGLEDFWCQCVAWS------SAGTTKSRKAHVRIAYLRKTFDQEPLGKEVSLEQEVLLQCRPPEGIPAAEVEWLKNEEVIDPAEDRNFYITIDHNLIIKQARLSDTANYTCVAKNIVAKRRSTTATVIVYVNGGWSTWTEW-----------SACNSRCGRGFQKRTRSCTNPAPLNGGAICEGQPIQKLACNPLCPVDGLWTEWSKWSTC-GTECTHWRRRECSAPAPKNGGKDCEGMVLQSKNCTDGLCMQTAPS-----------------TDDVALYVGIVIAVIMCLVISVIVALFVYRKNHRDFDSDIIDSSALNGGFQPV------------------------------SIKTARTADLLAAPPDLTSAAAMY----RGPVYALHDVADKIPMTNSPLLDPL-PNLKIKVYNSSGLVT----PQEDLSDFSSKLSPKLPHSLIDSDTMGRRTQSLVRSRDPSCTA-------------FGSFNSLGGHLIVPNSGVSLLVPAGAIPQGRVYEMYVTVHRKETMRPSVDDTQTVLSPVVSCGPPGALLTRPVIITMHHCA-EADSEDWLIQLRSQ----SQQGQWEDVV-VVGEENFTTPCYIQMDEEACHILTETLGTYCLVGQSV-SAATTKRLKLAVFGPVTCTALEYN-------IRVYCLDDTQDALKEVLQME-KQMGGKLLDEPKTLNFKDSTHNLRLSLHDVPHTLWKSKLLAKYQELSFQHVWSGSQRNLHCTFTL-----------ERFSAGTLELG--CKLCVRQVEGEGQ----------------IFQLNTTLSEDSQCIDTSLLDPASNITTLVGPNAFRIPLSIRQKLCSSLDAPQTRGNDWRMLAHKLNLDRYLNYFATKSSPTGVILDLWEAQHFPDGNLNRLAAVLEEMGR 915
BLAST of Unc-5 netrin receptor B vs. Ensembl Cavefish
Match: unc5b (unc-5 netrin receptor B [Source:NCBI gene;Acc:103042383]) HSP 1 Score: 278.87 bits (712), Expect = 1.503e-78 Identity = 271/1025 (26.44%), Postives = 429/1025 (41.85%), Query Frame = 3
Query: 369 EGVPKFIQQPKSMYYVSKSHPAVITCIAQPVSHVNIFCADKQYSYMNEEVSATGLKVIKMDNEGRLAVKGNRWKFSLEVQHKDVIEWFS--EYRCHCEAWNQIEQLQKVKKVESSSAVIYDSYINKDFKTVPKNQKVSVRGSVKLSCIPPDAKPPAEIHWVKNGEKITGKSHPQFEINEYGELLLSNIRLTDSGNYSCVASSF-GLERHATAQILVFEVGQWSDWSEWTGICPNICSKGSNCPKVCSTSRQQRVRYCNQIK--NQKANCIGSEIEYKRCDLICDPNL-WTFWSEWSKCSGNPCKKERTRQCTT---NNCGK---ASSVEIDNCTLAECGGFVASFINSNKKYPESSTSIYITHDVAMYIGLFVAVSVFLMVVAIIFCLIRRRVIGFSPNRVWRYSTTANGIQMFYPDXXXXXXXXXXXXXXXXXXDINQPSLYRSIVLPNSLPFLPSNQSDASSNSAYTDVGNDITYIQRNHLPS---LPMIATPLLSSMKPTLKIRPSYSDSKVSSTLYPQM-----GLVKHVSTLPIPVSSSLSDHYQELGNTDNETSDQSVTEPCLPYNFNGENMIWATIDSSGGRISLALSDINLTCPPNSFAPGISEPIFLATCNSEQDLPNLSANETLLSPVVVCGPTNVIAFKPFILNIPHCAYNTDSGNWAISVLTSYSPLKQKPYWQKYLDLDAEDKDSPPGYAQLAKDRLFLITNQLQRFCVVGSSYRNKRATKVLRIAAY-----CTGLDRRHADEQIVVRLYLIPDIAECISKVHNFETNRLGARLVTNQKQFFCEDEAGNITVVISDLAMD-WQASSANNYQEIPFKDVWHSPT--LHCSFNFIKRLINANSSELKISVNSLDFNWFCTLSIYQTNSHHNKQTVLLSTPNGSSHTSISATSTQFSNYSAGG-----SQSFPYFVDDCSKTNFESVFKLPEQTKIKLCKLLDSLTPLDNDWRQLARHLSITRSLQFFSNKLSSTEILLDLWEAQNHSRKSLNNLIDILRKMGRLDCVAILEKD 3344
E +P+F +P+ + V K+ P ++C A P + + C + ++ N+ V+ L I L V+ + + V V E F +Y C C AW SS+ Y+ N F+ P ++V + V L C PP+ PPAE+ W+KN + I F + +L++ RL+D+ NY+CVA + R +TA ++V+ G WS W+EW S C C Q+R R C N A C G + C +C + WT W++WS C G C R+R+C N G+ S +E NCT C + ++S VA+Y GL A+ + +++V + L RR + S+ F+P Y+ N PS D ++ SA T G + +Q++ L S +PM +PLL + P LKI+ Y S +SS P G + + T V S DHY G+T S + AT+ GGR+++ + ++L PP + G ++L E+ +T+LSPVV CGP+ ++ +P IL +PHCA + +W++++ T + W++ L + E+ S P Y Q+ + ++ QL + +VG S + A K L++A + C LD +R+Y I D + +V E + LG L+ + K +D N+ + I D+ W++ YQEIPF +W LHC+F+ + + + KI V ++ I+Q HT I T S AGG SQ PY F+LP + K+C LD+ + DWR LA L R L +F+ K S T +LLDLWEA + L +L L +MG+ + + ++ D
Sbjct: 48 EPLPEFQSEPEDAFIV-KNRPVKLSCKAAPATQIYFKC-NGEWVNQNDHVTRESLDQIT-----GLVVR----EVDISVSRTQVEELFGLEDYWCQCVAW-------------SSAVSTYEKLSN--FEQEPLGREVRLEQEVLLQCRPPEGIPPAEVEWLKNEDLIDPTQDSNFLMTVDHDLIIKQARLSDTANYTCVARNVVAKRRSSTATLIVYVSGGWSSWTEW-----------SECNARCGRGWQRRTRSCTNPAPLNGGAFCEGPPFQRVTCTTLCPVDGGWTEWAKWSAC-GTECTHWRSRECQAPPPRNGGRHCIGSIMESKNCTEGLCARSESHALDSGA-------------GVAVYAGLVGALLLCVILVLCVGILAYRRSCSHLHGDITDSSSALTA--AFHPGN------------------------YKPPRQDNPHLLHPSAPPDLTA-SAGTFRGPLFSSLQQSTLDSHHKIPMTNSPLLDPL-PGLKIK-VYDSSTMSSVELPAGPGSSDGEIMSLKT----VGSGTRDHY---GHTLPGEPGHSAS---------------ATLGCLGGRLAIPNTGVSLLVPPGTIPQGKFYEMYLIINKWEKTTLPSEGGQTVLSPVVSCGPSGMLLSRPVILTLPHCA-QLEPPDWSLTLKT-----QTNQAWEEVLTV-GEESLSSPCYLQVEEQNCHVLMEQLGTYGLVGQSVPPQPACKRLQLALFAPRAPCLSLDYS-------LRVYCIHDTPHALKEVLELERS-LGGVLLEDPKPLLFKDSYHNLRLSIHDIPHSHWRSKLLAKYQEIPFYHIWSGSQRPLHCTFSLERGSLAVSQLSCKICVRQVEGEG----QIFQL------------------HTDIQETLPPHSPLPAGGTCLPSSQVGPY------------AFRLPASIRQKICASLDAPSARGCDWRLLAHSLGFDRYLNYFATKPSPTGVLLDLWEACHQGDADLVSLATALEEMGKSEVLVVMTTD 921
BLAST of Unc-5 netrin receptor B vs. Ensembl Cavefish
Match: unc5b (unc-5 netrin receptor B [Source:NCBI gene;Acc:103042383]) HSP 1 Score: 248.44 bits (633), Expect = 1.380e-68 Identity = 253/977 (25.90%), Postives = 403/977 (41.25%), Query Frame = 3
Query: 369 EGVPKFIQQPKSMYYVSKSHPAVITCIAQPVSHVNIFCADKQYSYMNEEVSATGLKVIKMDNEGRLAVKGNRWKFSLEVQHKDVIEWFS--EYRCHCEAWNQIEQLQKVKKVESSSAVIYDSYINKDFKTVPKNQKVSVRGSVKLSCIPPDAKPPAEIHWVKNGEKITGKSHPQFEINEYGELLLSNIRLTDSGNYSCVASS-FGLERHATAQILVFEVGQWSDWSEWTGICPNICSKGSNCPKVCSTSRQQRVRYCNQIK--NQKANCIGSEIEYKRCDLICDPN-LWTFWSEWSKCSGNPCKKERTRQCTT---NNCGK---ASSVEIDNCTLAECGGFVASFINSNKKYPESSTSIYI--THDVAMYIGLFVAVSVFLMVVAIIFCLIRRRVIGFSPNRVWRYSTTANGIQMFYPDXXXXXXXXXXXXXXXXXXDINQPSLYRSIVLPNSLPFLPSNQSDAS-SNSAYTDVGNDITYIQRNHLPS---LPMIATPLLSSMKPTLKIRPSYSDSKVSSTLYPQM-----GLVKHVSTLPIPVSSSLSDHYQELGNTDNETSDQSVTEPCLPYNFNGENMIWATIDSSGGRISLALSDINLTCPPNSFAPGISEPIFLATCNSEQDLPNLSANETLLSPVVVCGPTNVIAFKPFILNIPHCAYNTDSGNWAISVLTSYSPLKQKPYWQKYLDLDAEDKDSPPGYAQLAKDRLFLITNQLQRFCVVGSSYRNKRATKVLRIAAY-----CTGLDRRHADEQIVVRLYLIPDIAECISKVHNFETNRLGARLVTNQKQFFCEDEAGNITVVISDLAMD-WQASSANNYQEIPFKDVWHSPT--LHCSFNFIKRLINANSSELKISVNSLDFNWFCTLSIYQTNSHHNKQTVLLSTPNGSSHTSISATSTQFSNYSAGG-----SQSFPYFVDDCSKTNFESVFKLPEQTKIKLCKLLDSLTPLDNDWRQLARHLSITR 3191
E +P+F +P+ + V K+ P ++C A P + + C + ++ N+ V+ L I L V+ + + V V E F +Y C C AW+ +S A + +Y+ K+F+ P ++V + V L C PP+ PPAE+ W+KN + I F + +L++ RL+D+ NY+CVA + R +TA ++V+ G WS W+EW S C C Q+R R C N A C G + C +C + WT W++WS C G C R+R+C N G+ S +E NCT C NKK T+ + VA+Y GL A+ + +++V + L RR + S+ F+P + P Q+ + SA T G + +Q++ L S +PM +PLL + P LKI+ Y S +SS P G + + T V S DHY G+T S + AT+ GGR+++ + ++L PP + G ++L E+ +T+LSPVV CGP+ ++ +P IL +PHCA + +W++++ T + W++ L + E+ S P Y Q+ + ++ QL + +VG S + A K L++A + C LD +R+Y I D + +V E + LG L+ + K +D N+ + I D+ W++ YQEIPF +W LHC+F+ + + + KI V ++ I+Q HT I T S AGG SQ PY F+LP + K+C LD+ + DWR LA L R
Sbjct: 23 EPLPEFQSEPEDAFIV-KNRPVKLSCKAAPATQIYFKC-NGEWVNQNDHVTRESLDQITG-----LVVR----EVDISVSRTQVEELFGLEDYWCQCVAWS------SAGTTKSRRAYVRIAYLRKNFEQEPLGREVRLEQEVLLQCRPPEGIPPAEVEWLKNEDLIDPTQDSNFLMTVDHDLIIKQARLSDTANYTCVARNVVAKRRSSTATLIVYVSGGWSSWTEW-----------SECNARCGRGWQRRTRSCTNPAPLNGGAFCEGPPFQRVTCTTLCPVDGGWTEWAKWSAC-GTECTHWRSRECQAPPPRNGGRHCIGSIMESKNCTEGLCA--------RNKKISIEHTTHPLDSGAGVAVYAGLVGALLLCVILVLCVGILAYRRSCSHLHGDITDSSSALTA--AFHPGN-----------------------------------YKPPRQAPPDLTASAGTFRGPLFSSLQQSTLDSHHKIPMTNSPLLDPL-PGLKIK-VYDSSTMSSVELPAGPGSSDGEIMSLKT----VGSGTRDHY---GHTLPGEPGHSAS---------------ATLGCLGGRLAIPNTGVSLLVPPGTIPQGKFYEMYLIINKWEKTTLPSEGGQTVLSPVVSCGPSGMLLSRPVILTLPHCA-QLEPPDWSLTLKT-----QTNQAWEEVLTV-GEESLSSPCYLQVEEQNCHVLMEQLGTYGLVGQSVPPQPACKRLQLALFAPRAPCLSLD-------YSLRVYCIHDTPHALKEVLELERS-LGGVLLEDPKPLLFKDSYHNLRLSIHDIPHSHWRSKLLAKYQEIPFYHIWSGSQRPLHCTFSLERGSLAVSQLSCKICVRQVEGEG----QIFQL------------------HTDIQETLPPHSPLPAGGTCLPSSQVGPY------------AFRLPASIRQKICASLDAPSARGCDWRLLAHSLGFDR 852
BLAST of Unc-5 netrin receptor B vs. Ensembl Sea Lamprey
Match: ENSPMAT00000008404.1 (pep scaffold:Pmarinus_7.0:GL476608:255441:311832:-1 gene:ENSPMAG00000007555.1 transcript:ENSPMAT00000008404.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 264.233 bits (674), Expect = 2.335e-74 Identity = 266/1025 (25.95%), Postives = 413/1025 (40.29%), Query Frame = 3
Query: 369 EGVPKFIQQPKSMYYVSKSHPAVITCIAQPVSHVNIFC----ADKQYSYMNEEVSATGLKVIKMDNEGRLAVKGNRWKFSLEVQHKDVIEWFSEYRCHCEAWNQIEQLQKVKKVESSSAVIYDSYINKDFKTVPKNQKVSVRGSVKLSCIPPDAKPPAEIHWVKNGEKITGKSHPQFEINEYGELLLSNIRLTDSGNYSCVASSF-GLERHATAQILVFEVGQWSDWSEWTGICPNICSKGSNCPKVCSTSRQQRVRYCNQIK--NQKANCIGSEIEYKRCDLICDPN-LWTFWSEWSKCSGNPCKKERTRQCTTN---NCGK---ASSVEIDNCTLAECGGFVASFINSNKKYPESSTSIYIT----HDVAMYIGLFVAVSVFLMVV-AIIFCLIRRRVIGFSPNRVWRYSTTANGIQMFYPDXXXXXXXXXXXXXXXXXXDINQPSLYRSIVLPNSLPFLPSNQSDASSNSAYTDVGNDITYIQRNHLPSLPMIATPLLSSMKPTLKIRPSYSDSKVSSTLYPQMGLVKHVSTLPIPVSSSLSDHYQELGNTDNETSDQSVTEPCLPYN----FNGENMIWATIDSSGGRISLALSDINLTCPPNSFAPGISEPIFLATCNSEQDLPNLSANETLLSPVVVCGPTNVIAFKPFILNIPHCAYNTDSGNWAISVLTSYSPLKQKPYWQKYLDLDAEDKDSPPGYAQLAKDRLFLITNQLQRFCVVGSSYRNKRATKVLRIAAYCTGLDRRHADEQIVVRLYLIPDIAECISKVHNFETN---------------RLGARLVTNQKQFFCEDEAGNITVVISDLA-MDWQASSANNYQEIPFKDVWHS--PTLHCSFNFIKRLINANSSELKISVNSLDFNWFCTLSIYQTNSHHNKQTVLLSTPNGSSHTSISATSTQFSNYSAGGSQSFPYFVDDCSKTNFESVFKLPEQTKIKLCKLLDSLTPLDNDWRQLARHLSITRSLQFFSNKLSSTEILLDLWEAQNHSRKSLNNLIDILRKMGRLD 3320
E +P F+ +P + V ++ P + C A P + + C ++ Y E +S KV++ V N + +E ++ ++ C C AW+ +S A + +++ K+F+ P + V + V L C PP+A PPAE+ W+K+ E I + F I L++ RL+DS NY+CVA + R +TA + V+ G WS W+EW S C C Q+R R C N A C G + C IC + W WS+WS C G C R+R+C+ N GK S ++ NC+ A C I S K STS + +VA+Y G+ VA+ + + VV A F L RRR + + + S G F P Q + + +L R+ + P+ +A Y N + M +PLL + P + SS++ S P P + + + T D + TE CL N + ++ T GGR+++A S ++L PP + PG +++ ++ P L ++TLLSPVV CG +V P IL++ HCA +WA+S+ L P W++ L E P + Q + T L FC SS+ + R+ H D Y P + C H + + +LG RL+ + +GN+ + I + + W N +QEIPF VW LHC+F + +++ K+ V L+ + Q +T LL+ P+ + + A SAG + P FKLP + KLC LDS P NDWR LA L I R +F + S T ++LDLWEAQ+ L++L +L +MGR +
Sbjct: 8 EPLPIFLTEPNDGFIV-QNKPVTLDCSASPATQIYFKCNGEWLHQKALYTQEHLSEITGKVVR-------EVHTNVSRQQVEDPYR-----LEDFWCQCVAWS------ASGTTKSRKAFVKVAHLRKNFEQEPLGKDVPLNHEVLLHCRPPEAIPPAEVEWMKDKELIDPEEDSNFYITVDHNLIIKQARLSDSANYTCVAKNLVAKRRSSTATVTVYVNGGWSLWTEW-----------SPCNSKCGRGTQKRTRSCTNPAPLNGGAVCNGQGTQKIPCSTICPVDGGWVEWSKWSTC-GPDCTHWRSRECSNPAPVNGGKDCHGSPLQSQNCSDALC-------IQSEKIIIGQSTSCVLASEAGDEVALYAGVAVALVISVGVVLAASFVLYRRRRQEYGSDIIDSASALTGG---FRP------------VNQKAGRNADDSNLLRTAIQPDL--------------TASVGTFPQPVYPVHNATQKIQMTQSPLLEPL-------PGHKIKVCSSSMLASTDNEGDQSVEPSPKRHGTRQPNKMI---QHHTLDLAPTETCLDNNEMHQVGSDTTVFGTFCCLGGRLTIAHSGVSLLVPPGAIPPGQFYQMYITIHREKEKRPALENSQTLLSPVVSCGAPSVPLLSPVILSLRHCA-ELSPEDWALSLKRQ---LSSGP-WEEVLRQGEEPARPPSCHWQRVSVSVTSTTAHLVSFCYYCSSF----MSVCGRVC---------HQD-------YFSPCLCVCGRVCHQYYCSSSTHDQFKEVVELEKQLGGRLLEEPTTLNFKANSGNLRLSIHAIPDVLWTNKLLNTFQEIPFWHVWPGCQRLLHCTFALERASLSSTEFSCKLCVQQLEGEG----QVLQL------RTTLLNAPSATDDSPTEAA-------SAGSALVGP------------QAFKLPYSIRQKLCSSLDSPNPRGNDWRLLAHRLGINRYGNYFEMRGSPTGVVLDLWEAQHEEDGDLDSLASVLEEMGRRE 901
BLAST of Unc-5 netrin receptor B vs. Ensembl Sea Lamprey
Match: ENSPMAT00000003861.1 (pep scaffold:Pmarinus_7.0:GL476449:2630:55902:-1 gene:ENSPMAG00000003466.1 transcript:ENSPMAT00000003861.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 231.491 bits (589), Expect = 8.843e-64 Identity = 216/861 (25.09%), Postives = 363/861 (42.16%), Query Frame = 3
Query: 369 EGVPKFIQQPKSMYYVSKSHPAVITCIAQPVSHVNIFCADKQYSYMNEEVS-----ATGLKVIKMDNEGRLAVKGNRWKFSLEVQHKDVIEWFSEYRCHCEAWNQIEQLQKVKKVESSSAVIYDSYINKDFKTVPKNQKVSVRGSVKLSCIPPDAKPPAEIHWVKNGEKITGKSHPQFEINEYGELLLSNIRLTDSGNYSCVASSF-GLERHATAQILVFEVGQWSDWSEWTGICPNICSKGSNCPKVCSTSRQQRVRYCNQIK--NQKANCIGSEIEYKRCDLICD-PNLWTFWSEWSKCSGNPCKKERTRQCTTN---NCGK---ASSVEIDNCTLAECGGFVASFINSNKKYPESSTSIYITHDVAMYIGLFVAVSVFL-MVVAIIFCLIRRRVIGFSPNRVWRYSTTANGIQMFYPDXXXXXXXXXXXXXXXXXXDINQPSLYRSIVLPNSLPFLPSNQSDASSNSAYTDVGNDITYIQRNHLPSLPMIATPLLSSMKPTLKIRPSYSDSKVSSTLYPQMGLVKHVSTLPIPVSSSLSDHYQELGNTDNETSDQSVTEPCLPYNFNGENMIWATIDSSGGRISLALSDINLTCPPNSFAPGISEPIFLATCNSEQDLPNLSANETLLSPVVVCGPTNVIAFKPFILNIPHCAYNTDSGNWAISVLTSYSPLKQKPYWQKYLDLDAEDKDSPPGYAQLAKDRLFLITNQLQRFCVVGSSYRNKRATKVLRIAAY----CTGLDRRHADEQIVVRLYLIPDIAECISKVHNFETNRLGARLVTNQKQFFCEDEAGNITVVISDLAMD-WQASSANNYQEIPFKDVWHS--PTLHCSFNFIKRLINANSSELKISVNSLD 2882
E +P F+Q+ + Y V ++ P ++C A P + + C + S V TG V ++ + + Q +V Y C C AW+ +S A + +Y++K+F+ P+ ++ ++L C PPDA PPAE+ W+KN I + F I L++ RL+DS NY+CVA + R +TA + V+ G WS W+EW C + C +G+ Q+R+R C N C G E C C W WS+WS C G C R+R+C+ N GK S ++ NC+ A C +F Y + S ++A+Y G+ VA+ V + +V+A L RRR + + + S G P+ +++ N++ + + + +S++ N Y Q + + M LL + P LKI+ S + S+ + + G + LS E +D+ S++ ++ C P + + ++AT GGR+ + S + L PP + G ++L E P L ++TLLSPVV CGP ++ P IL++ HCA +WA+S+ S +W++ L L E P + QL + ++T + V+G + A K LR+AA+ C L+ +RLY + D E +++V E RLG +V + +G++ + + + W + + QEIPF VW LHC+F + +++ K+ V L+
Sbjct: 34 EPLPHFLQELEDAYIV-RNKPVTMSCAASPATQIYFKCNAEWVSQQAHHVQQRTDQGTGRSVREVQTD-------------VSRQQVEVYYGPEPYWCQCVAWS------AAGTSKSRKAYVRIAYLHKNFEMEPQGKEEPQGQKIQLHCRPPDAVPPAEVEWLKNEMLIDPEEDSNFHITADHNLIIKQARLSDSANYTCVAKNLVAKRRSSTATVTVYVEGGWSLWNEWA-PCNSKCGRGT----------QKRIRTCTNPAPLNGGPFCDGQASENTPCTSACPVDGGWVEWSKWSTC-GPDCTHWRSRECSNPAPVNGGKDCHGSPLQSQNCSDALCIQTKTNFTG----YTSTLFSSETGDELALYGGVAVALVVSVGIVLAASVALYRRRRQNYEADIINSNSDLYGGF---------------------------APAGQKAVRHDNTMQRMAMHSDLTARSSSF----NGPVYPQCDMTQKISMTHFQLLEPL-PGLKIKVCSSPTVSSADVSRENG-------------ARLSSRKLETDTSDSGVSERRRSQNCAPLHQDKGTSVYATFGCLGGRLLIPSSGVGLLVPPGAIPHGHFYQMYLTVHRGEDSGPVLDGSQTLLSPVVSCGPPSIPLLSPVILSLRHCA-ELSPEDWALSLKRQLS----SGHWEEVLRLGEEPARPPSCHWQLEERACHVLTETPGTYAVLGEAL-GPAAVKRLRLAAFAPSVCPSLE-------YSLRLYCLNDDTESLAEVVELE-KRLGGHMVGEPSTLHFKANSGHLQLSMHAVPDTLWTNNVHSKLQEIPFWHVWPGCQRLLHCTFALERAGLSSTEFSCKLCVQQLE 799
BLAST of Unc-5 netrin receptor B vs. Ensembl Sea Lamprey
Match: ENSPMAT00000010609.1 (pep scaffold:Pmarinus_7.0:GL476332:154004:216612:1 gene:ENSPMAG00000009605.1 transcript:ENSPMAT00000010609.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 171.4 bits (433), Expect = 1.073e-43 Identity = 128/432 (29.63%), Postives = 200/432 (46.30%), Query Frame = 3
Query: 2043 IWATIDSSGGRISLALSDINLTCPPNSFAPGISEPIFLATCNSEQDLPNLSANETLLSPVVVCGPTNVIAFKPFILNIPHCAYNTDSGNWAISVLTSYSPLKQKPYWQKYLDLDAEDKDSPPGYAQLAKDRLFLITNQLQRFCVVGSSYRNKRATKVLRIAAY----CTGLDRRHADEQIVVRLYLIPDIAECISKVHNFETNRLGARLVTNQKQFFCEDEAGNITVVISDLA-MDWQASSANNYQEIPFKDVWHS--PTLHCSFNFIKRLINANSSELKISVNSLDFNWFCTLSIYQTNSHHNKQTVLLSTPNGSSHTSISATSTQFSNYSAGGSQSFPYFVDDCSKTNFESVFKLPEQTKIKLCKLLDSLTPLDNDWRQLARHLSI-TRSLQFFSNKLSSTEILLDLWEAQNHSRKSLNNLIDILRKMGR 3314
++ T GGR+ + S ++L PP + G ++L E P L ++TLLSPVV CGP +V P IL++ HCA +S +WA+ + +W++ L L E P + QL + ++T + V+G + A K LR+AA+ C L + +RLY + D AE +++V E +LG RL+ + +GN+ + I + + W N +QEIPF VW LHC+F + +++ K+ V L+ + Q +T LL+ P+ + + A SAG + P FKLP + KLC LDS P NDWR LA L I + S+++F + S T ++LDLWEAQ+ L++L +L +MGR
Sbjct: 577 VYGTFGCMGGRLVIPNSGLSLLVPPGAIPSGQFYQMYLTVHRDEDKRPVLEGSQTLLSPVVSCGPPSVPLLSPVILSLRHCA-ELNSEDWALGLKRQLD----SGHWEEVLRLGEEPARPPSCHWQLEERACHVLTETPGTYAVLGEAL-GPAAVKRLRLAAFAPSVCPSL-------EYSLRLYCLNDDAESLAEVVELE-KQLGGRLLEEPTTLSFKANSGNLRLSIHAIPDVLWTNKLLNTFQEIPFWHVWPGCQRLLHCTFALERAGLSSTEFSCKLCVQQLEGEG----QVLQL------RTTLLNAPSATDDSPTEAA-------SAGSALVGP------------QAFKLPYSIRQKLCSSLDSPNPRGNDWRLLAHRLGINSASMEYFETRGSPTGVVLDLWEAQHEEDGDLDSLASVLEEMGR 965 HSP 2 Score: 148.673 bits (374), Expect = 1.358e-36 Identity = 115/398 (28.89%), Postives = 177/398 (44.47%), Query Frame = 3
Query: 369 EGVPKFIQQPKSMYYVSKSHPAVITCIAQPVSHVNIFCAD----KQYSYMNEEVSATGLKVIKMDNEGRLAVKGNRWKFSLEVQHKDVIEWFS--EYRCHCEAWNQIEQLQKVKKVESSSAVIYDSYINKDFKTVPKNQKVSVRGSVKLSCIPPDAKPPAEIHWVKNGEKITGKSHPQFEINEYGELLLSNIRLTDSGNYSCVASSF-GLERHATAQILVFEVGQWSDWSEWTGICPNICSKGSNCPKVCSTSRQQRVRYCNQIK--NQKANCIGSEIEYKRCDLICD-PNLWTFWSEWSKCSGNPCKKERTRQCTTN---NCGK---ASSVEIDNCTLAECGGFVASFINSNKKYPESSTSIYITHDVAMYIGL--FVAVSVFLMVVAIIFCLIRRR 1508
E +P F+Q+P+ Y V ++ P ++C A P + + C ++ ++ E V T + ++ + +V + V E F +Y C C AW+ +S A + +Y+ K+F+ P + V + V L C PPDA P AE+ W+KN E I F I L++ RL DS NY+CVA + R +TA I V+ G WS W+EW S C C Q+R R C+ N A C G +E C +C W WS+WS C G C R+R+C+ N GK S ++ NC+ A C + + K E +S +VA+Y G+ V ++V +++ A I RR+
Sbjct: 55 EPLPHFLQEPEDAYIV-RNKPVTMSCAASPATQIYFKCNGEWLHQKAHHIEERVDETTGRSVR--------------EVQTDVSRQQVEELFGLEDYWCQCVAWS------AAGTSKSRKAYVRIAYLRKNFEQEPLGKDVLLDHEVLLHCRPPDAIPQAEVEWLKNEEIIDPVIDQNFYITVDHNLIIKQTRLADSANYTCVAKNLVAKRRSSTATITVYVNGGWSQWTEW-----------SPCNSKCGRGTQKRTRSCSNPTPLNGGAVCDGQGVEKMPCSSLCPVDGGWVEWSKWSTC-GPDCTHWRSRECSNPAPVNGGKDCHGSPLQSQNCSDALC-------LQNAKYRDELYSSEARGDEVALYAGVAAVVVITVGIVLAAAILLYKRRQ 412
BLAST of Unc-5 netrin receptor B vs. Ensembl Sea Lamprey
Match: tjp1a (tight junction protein 1a [Source:ZFIN;Acc:ZDB-GENE-031001-2]) HSP 1 Score: 63.1586 bits (152), Expect = 3.580e-10 Identity = 32/99 (32.32%), Postives = 51/99 (51.52%), Query Frame = 3
Query: 2049 ATIDSSGGRISLALSDINLTCPPNSFAPGISEPIFLATCNSEQDLPNL--SANETLLSPVVVCGPTNVIAFKPFILNIPHCAYNTDSGNWAISVLTSYS 2339
DS+GG +S + +++ P + G+ + I+ C +P L ETLLSP+V+CGP + KP L +PHCA G W+ ++ +S S
Sbjct: 1640 GVFDSNGGVLSSVETGVSVVVPRGAIPEGLEQEIYFKVCQDNSIIPALDKEKGETLLSPLVMCGPHGLRFLKPVELRLPHCAAMNPDG-WSFALKSSES 1737
BLAST of Unc-5 netrin receptor B vs. Ensembl Sea Lamprey
Match: ENSPMAT00000002817.1 (pep scaffold:Pmarinus_7.0:GL476732:495093:569098:-1 gene:ENSPMAG00000002526.1 transcript:ENSPMAT00000002817.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 57.7658 bits (138), Expect = 1.734e-8 Identity = 29/87 (33.33%), Postives = 44/87 (50.57%), Query Frame = 3
Query: 2058 DSSGGRISLALSDINLTCPPNSFAPGISEPIFLATCNSEQDLPNLSAN--ETLLSPVVVCGPTNVIAFKPFILNIPHCAYNTDSGNW 2312
D+ GG +S + +++ P + P + + I+ C LP L ETLLSP+V+CGP + KP L +PHC + NW
Sbjct: 1597 DTHGGVLSSVETGVSIIIPKGAIPPAVEQEIYFKVCKDNSILPPLDKEKGETLLSPLVMCGPHGLKFLKPVELRLPHC----EPSNW 1679
BLAST of Unc-5 netrin receptor B vs. Ensembl Nematostella
Match: EDO46601 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RPN0]) HSP 1 Score: 84.3445 bits (207), Expect = 2.153e-16 Identity = 102/467 (21.84%), Postives = 176/467 (37.69%), Query Frame = 3
Query: 1986 SDQSVTEPCLPYNFNGENMIWATIDSSGGRISLALSDINLTCPPNSFAPGISEPIFLATCNSEQDLPNLSANETLLSPVVVCGPTNVIAFKPFILNIPHCAYNTDSGNWAISVLTSYSPLKQKPYWQKYLDLDAEDKDSPPGYAQLAKDRLFLITNQLQRFCVVGS-SYRNKRATKVLRIAAYCTGLDRRHADEQIVVRLYLIPDIAECISKVHNFETNRLGARLVTNQKQFFCEDEAGNITV--VISDLAMDWQASSANNYQEIPFKDVWHS----PTLHCSFNFIKRLINANSSELKISVNSLDFNWFCTLSIYQTNSHHNKQTVLLSTPNGSSHTSISATSTQFSNYSAGGSQSFPYFVDDCSKTNFESVFKLPEQTKIKLCKLLDSLTPLDN----DWRQLARHL-SIT----RSLQFFSNKLSSTEILLDLWEAQNHSRKSLNNLIDILRKMGRLDCVAILE 3338
S Q P LP + W ID +GG++ + + I+L PP++ G E I++A P L + LLSP VVCGP + +P L +PH A + + T W+ LD + + P Y L ++ + ++ VVG Y + L+ C G A V++YLIP + + + +R+G K F + + ++ V + ++ W+ + Q +PF VW S P + F I N + + + + H ++ + S+ T S+ + + + + S+ + K+P +IKLC L+ P DN W+ LA + IT R L+ L+D WE + L+ L ++ +GR D ++E
Sbjct: 580 SKQQCPRPSLPERADERLCAWGRIDHNGGQLVIPNTGISLYVPPSALPQGQEEVIYIAMMKRSAKYPQLRPGQALLSPAVVCGPEGLQFNEPVFLKLPHNAALKNGEIPHLEGKTRSGESTDATTWRTLESLDGDPESRPISY--LDENSVEMMLTHFSDQTVVGEPEYLKIKVVPFLQ----CDG-----AQFDCRVQVYLIPRTKAALEEA-ILDASRVGLIQADTGKLFSLMNTSRDVRVKACLHEVDTKWKPVTPVQ-QALPFSQVWSSVEDMPNVTFGFAPIPDQPNLTTFRCNFEIQQYGETDLARIFVTYCIKDHEEEGAV----GSSASTPTSSPQRKLERWDSSSTLGI------GSEMQGPNENKIPRDIRIKLCIKLE---PADNLMIGSWKDLAGKIPGITTDHIRYLEGRKVGDGPVGALIDYWETSLSEKIPLHQLAQLMEDIGRRDAAELVE 1020
BLAST of Unc-5 netrin receptor B vs. Ensembl Nematostella
Match: EDO41849 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S398]) HSP 1 Score: 70.0922 bits (170), Expect = 4.313e-12 Identity = 60/256 (23.44%), Postives = 109/256 (42.58%), Query Frame = 3
Query: 2064 SGGRISLALSDINLTCPPNSFAPGISEPIFLATCNSEQDLPNL--SANETLLSPVVVCGPTNVIAFKPFILNIPHCAYNTDSGNWAISVLTSYSPLKQKPYWQKYLDLDAEDKDSPPGYAQLAKDRLFLITNQLQRFCVVGSSYRNKRATKVLRIAAYCTGLDRRHADEQIVVRLYLIPDIAECISKVHNFETNRLGARLVTNQKQFFCEDEAGNITVVISDLAMDWQASSANNYQEIPFKDVWHSPTLHCSFNFI 2825
GG +S S +++ P + G+ + I+ C +P L ETLLSP+V+CGP K L +PHCA T G W+ ++ +S +P W+ E KD Q+ + + ++ + F + G + N ATK + + + + + + + L ++ +V ET G + +A ++ V + D+A W + SA + I F+D W + + + NF+
Sbjct: 820 EGGVLSSEESGVSIFIPEGAIPKGVEQEIYFKVCKENNIMPPLDTEKGETLLSPLVMCGPHGTKFLKSVELRLPHCAAMTPDG-WSFALKSSDTPTGMPTQWRNVSLPGQEHKDK----CQVDPNSVSVLVDHFSSFSLAGEARSN--ATKRMVASVFAQPP---MTNSEWLFHVVLADNMDSARREVQQAETA-CGRLQFSPFVPIDVHGDAKDVRVQLRDIADGWISRSACK-KYIEFQDTWEAYLQNPTVNFV 1063
BLAST of Unc-5 netrin receptor B vs. Ensembl Nematostella
Match: EDO33294 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SSL1]) HSP 1 Score: 62.3882 bits (150), Expect = 1.794e-10 Identity = 47/172 (27.33%), Postives = 71/172 (41.28%), Query Frame = 3
Query: 744 FKTVPKNQKVSVRGSVKLSCIPPDAKPPAEIHWVKNGEKITGKSHPQFEINEYGELLLSNIRLTDSGNYSCVASSFGLERHATAQILVFEVGQWSDWSEWTGICPNICSKGSNCPKVCSTSRQQRVRYCNQ--IKNQKANCIGSEIEYKRCDL-ICD-PNLWTFWSEWSKCS 1247
F P++ + + GSV L P + W KNG+ P I LL++ ++ D+G+Y C A+ L A ++V G WS W WT C + C T + R R C+ + A C GS + +RC C P W+ W W+ C+
Sbjct: 1 FTRTPQDTAIDL-GSVLLWHCTATGYPTPVLTWQKNGQGFNPWWPPHIRILANNSLLINGVKREDAGSYQCRATINSLSNAIQAVLIVRVPGGWSAWQSWT-----------PCTQSCGTGLRYRYRACDNPFPAHGGATCPGSNEDRERCSAQPCPVPGGWSAWQSWTPCT 160
BLAST of Unc-5 netrin receptor B vs. Ensembl Nematostella
Match: EDO31173 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SYQ3]) HSP 1 Score: 48.1358 bits (113), Expect = 1.311e-6 Identity = 35/122 (28.69%), Postives = 46/122 (37.70%), Query Frame = 3
Query: 1017 GQWSDWSEWTGICPNICSKGSNCPKVCSTSRQQRVRYCNQ--IKNQKANCIGSEIEYKRCDLICDP--NLWTFWSEWSKCSGN--PCKKERTRQC---TTNNCGKA---SSVEIDNCTLAEC 1346
G W W+ W S C K C Q R R C+ KN + C+G + + C + P W W+ WS CS + RTR C N G A S + C +A C
Sbjct: 3 GHWGRWTAW-----------SACSKTCGDGTQTRTRVCDDPAPKNGGSACVGDSSQTQACKIATSPVDGHWGSWTAWSACSKTCGDGTQTRTRMCDDPAPKNGGSACVGDSSQTQACKIATC 113
BLAST of Unc-5 netrin receptor B vs. Ensembl Nematostella
Match: EDO40760 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S664]) HSP 1 Score: 51.9878 bits (123), Expect = 1.717e-6 Identity = 34/97 (35.05%), Postives = 46/97 (47.42%), Query Frame = 3
Query: 1017 GQWSDWSEWTGICPNICSKGSNCPKVCSTSRQQRVRYCNQIK--NQKANCIGSEIEYKRC-DLICDPN-LWTFWSEWSKCSG--NPCKKERTRQCTT 1289
G WSD+S W S+C K C Q R R C K + C+G E + C + C N W+ +S+W+KCS K+ERTR CT+
Sbjct: 287 GGWSDYSSW-----------SSCTKTCGGGTQTRTRTCTNPKPAHGGKECVGDAKETRHCSEAACAVNGGWSDFSKWTKCSKTCGGGKQERTRTCTS 372
BLAST of Unc-5 netrin receptor B vs. Ensembl Medaka
Match: si:ch73-72b7.1 (netrin receptor UNC5C [Source:NCBI gene;Acc:101174433]) HSP 1 Score: 293.893 bits (751), Expect = 1.354e-83 Identity = 269/1010 (26.63%), Postives = 436/1010 (43.17%), Query Frame = 3
Query: 369 EGVPKFIQQPKSMYYVSKSHPAVITCIAQPVSHVNIFCADKQYSYMNEEVSATGLKVIKMDNEGRLAVKGNRWKFSLEVQHKDVIEWFS--EYRCHCEAWNQIEQLQKVKKVESSSAVIYDSYINKDFKTVPKNQKVSVRGSVKLSCIPPDAKPPAEIHWVKNGEKITGKSHPQFEINEYGELLLSNIRLTDSGNYSCVASSFGLERHA-TAQILVFEVGQWSDWSEWTGICPNICSKGSNCPKVCSTSRQQRVRYCNQIK--NQKANCIGSEIEYKRCDLICDPN-LWTFWSEWSKCSGNPCKKERTRQCTT---NNCGKASS---VEIDNCTLAECGGFVASFINSNKKYPESSTSIYI-----THDVAMYIGLFVAVSVFLMVVAIIFCLIRRRVIGFSPNRVWRYSTTANGIQMFYPDXXXXXXXXXXXXXXXXXXDI-NQPSLYRSIVLPNSLPFLPSNQSDASSNSAYTDVGNDITYIQRNHLPSLPMIATPLLSSMKPTLKIRPSYSDSKVSSTLYPQMGLVKH-VSTLPIPVSSSLSDHYQELGNTDNETSDQSVTEPCLPYNFNGENMIWATIDSSGGRISLALSDINLTCPPNSFAPGISEPIFLATCNSEQDLPNLSANETLLSPVVVCGPTNVIAFKPFILNIPHCAYNTDSGNWAISVLTSYSPLKQKPYWQKYLDLDAEDKDSPPGYAQLAKDRLFLITNQLQRFCVVGSSYRNKRATKVLRIAAY----CTGLDRRHADEQIVVRLYLIPDIAECISKVHNFETNRLGARLVTNQKQFFCEDEAGNITVVISDLA-MDWQASSANNYQEIPFKDVWHSP--TLHCSFNFIKRLINANSSELKISVNSLDFNWFCTLSIYQTNSHHNKQTVLLSTPNGSSHTSISATSTQFSNYSAGGSQSFPYFVDDCSKTNFESVFKLPEQTKIKLCKLLDSLTPLDNDWRQLARHLSITRSLQFFSNKLSSTEILLDLWEAQNHSRKSLNNLIDILRKMGRLD 3320
E +P F+ +P+ Y V K+ P + C A P + + C + + V ++D L V+ + S+E+ + V E F +Y C C AW+ +S A + +Y+ K F+ P ++VS+ V L C PP+ P AE+ W+KN E I F I L++ RL+D+ NY+CVA + +R + TA ++V+ G WS W+EW S C C Q+R R C N C G I+ C +C + +WT WS+WS C G C + R R+C N GK ++ NCT C + S + P+ T + + T DVA+Y+G+ +AV + L++ I+ + R+ + + S G Q ++ + ++ D+ N ++YR V A DV + I PM +PLL + P LKI+ S V+ PQ L S L ++ SL ++ + N N++ +S C + + +S GG + + S ++L P + G + + + P + +T+LSPVV CGP + +P IL I HCA N +W I + S W+ + + E+ + P Y Q+ + ++T L +C+VG S K A K L++A + CT LD +R+Y + D + + +V ET ++G +L+ K +D N+ + I D+ M W++ YQEIPF VW +LHC+F ++RL A +++S C L + Q Q LS + + T + ++ + + + F++P + KLC LD+ NDWR LA L++ R L +F+ K S T ++LDLWEAQ+ LN L +L +MGR D
Sbjct: 62 EPLPHFLFEPEEGYIV-KNKPVNLYCKATPATQIYFKCNSEWVHQKDHTVEE------RVDENSGLVVR----EASIEITRQQVEELFGPEDYWCQCVAWS------SAGTTKSRKAHVRIAYLKKSFEQEPLGKEVSLEQEVLLQCRPPEGIPAAEVEWLKNEEVIDPAEDRNFYITIDHNLIIKQARLSDTANYTCVAKNIVAKRRSTTATVIVYVNGGWSTWTEW-----------SPCNSRCGRGFQKRTRSCTNPTPLNGGLPCDGQAIQKLPCTTLCTVDGVWTEWSKWSAC-GTECTQWRRRECNNPAPKNGGKDCEGLVLQSQNCTDGLC---MQSSLFQKSNVPKEKTDLGMPSAPSTDDVALYVGIVIAVIMCLVISVIVALFVYRKTHRDFDSDIIDTSALNGGFQ------SVNIKTARSADLLTAPPDLTNAAAMYRGPVY------------------ALHDVSDKI-----------PMTNSPLLDPL-PNLKIKVYNSSGLVT----PQDDLGGDFTSKLSPKITQSLLENSDTM-NLRNQSLARSRDPSCTAH---------GSFNSQGGHLIVPNSGVSLLVPAGAIPQGRVYEMCVTVHRKDSLRPPVEDIQTVLSPVVSCGPAGALLTRPVILTIHHCADNVQE-DWLIQLKNRLS----MGEWEDVV-VVGEENFTTPCYVQMDSEACHILTETLGTYCLVGQSI-GKAAAKRLKLAVFGPVSCTTLDYH-------IRVYCLDDTQDALKEVLQMET-QMGGKLLDEPKTLNFKDSTHNLRLSIHDVPHMQWKSKLIAKYQEIPFHQVWSGSQRSLHCTFT-LERLTPAT---MELS---------CKLCVRQVEGE--GQIFQLSN---TLEEELQCIDTSLMDPAS-----------NITTLTGPNAFRIPLSIRQKLCGSLDAPQTRGNDWRMLAHKLNLDRYLNYFATKSSPTGVILDLWEAQHFPDGDLNELAAVLEEMGRHD 945
BLAST of Unc-5 netrin receptor B vs. Ensembl Medaka
Match: si:ch73-72b7.1 (netrin receptor UNC5C [Source:NCBI gene;Acc:101174433]) HSP 1 Score: 289.271 bits (739), Expect = 3.735e-82 Identity = 267/1005 (26.57%), Postives = 429/1005 (42.69%), Query Frame = 3
Query: 369 EGVPKFIQQPKSMYYVSKSHPAVITCIAQPVSHVNIFCADKQYSYMNEEVSATGLKVIKMDNEGRLAVKGNRWKFSLEVQHKDVIEWFS--EYRCHCEAWNQIEQLQKVKKVESSSAVIYDSYINKDFKTVPKNQKVSVRGSVKLSCIPPDAKPPAEIHWVKNGEKITGKSHPQFEINEYGELLLSNIRLTDSGNYSCVASSFGLERHA-TAQILVFEVGQWSDWSEWTGICPNICSKGSNCPKVCSTSRQQRVRYCNQIK--NQKANCIGSEIEYKRCDLICDPN-LWTFWSEWSKCSGNPCKKERTRQCTT---NNCGKASS---VEIDNCTLAECGGFVASFINSNKKYPESSTSIYITHDVAMYIGLFVAVSVFLMVVAIIFCLIRRRVIGFSPNRVWRYSTTANGIQMFYPDXXXXXXXXXXXXXXXXXXDI-NQPSLYRSIVLPNSLPFLPSNQSDASSNSAYTDVGNDITYIQRNHLPSLPMIATPLLSSMKPTLKIRPSYSDSKVSSTLYPQMGLVKH-VSTLPIPVSSSLSDHYQELGNTDNETSDQSVTEPCLPYNFNGENMIWATIDSSGGRISLALSDINLTCPPNSFAPGISEPIFLATCNSEQDLPNLSANETLLSPVVVCGPTNVIAFKPFILNIPHCAYNTDSGNWAISVLTSYSPLKQKPYWQKYLDLDAEDKDSPPGYAQLAKDRLFLITNQLQRFCVVGSSYRNKRATKVLRIAAY----CTGLDRRHADEQIVVRLYLIPDIAECISKVHNFETNRLGARLVTNQKQFFCEDEAGNITVVISDLA-MDWQASSANNYQEIPFKDVWHSP--TLHCSFNFIKRLINANSSELKISVNSLDFNWFCTLSIYQTNSHHNKQTVLLSTPNGSSHTSISATSTQFSNYSAGGSQSFPYFVDDCSKTNFESVFKLPEQTKIKLCKLLDSLTPLDNDWRQLARHLSITRSLQFFSNKLSSTEILLDLWEAQNHSRKSLNNLIDILRKMGRLD 3320
E +P F+ +P+ Y V K+ P + C A P + + C + + V ++D L V+ + S+E+ + V E F +Y C C AW+ +S A + +Y+ K F+ P ++VS+ V L C PP+ P AE+ W+KN E I F I L++ RL+D+ NY+CVA + +R + TA ++V+ G WS W+EW S C C Q+R R C N C G I+ C +C + +WT WS+WS C G C + R R+C N GK ++ NCT C S T DVA+Y+G+ +AV + L++ I+ + R+ + + S G Q ++ + ++ D+ N ++YR V A DV + I PM +PLL + P LKI+ S V+ PQ L S L ++ SL ++ + N N++ +S C + + +S GG + + S ++L P + G + + + P + +T+LSPVV CGP + +P IL I HCA N +W I + S W+ + + E+ + P Y Q+ + ++T L +C+VG S K A K L++A + CT LD +R+Y + D + + +V ET ++G +L+ K +D N+ + I D+ M W++ YQEIPF VW +LHC+F ++RL A +++S C L + Q Q LS + + T + ++ + + + F++P + KLC LD+ NDWR LA L++ R L +F+ K S T ++LDLWEAQ+ LN L +L +MGR D
Sbjct: 47 EPLPHFLFEPEEGYIV-KNKPVNLYCKATPATQIYFKCNSEWVHQKDHTVEE------RVDENSGLVVR----EASIEITRQQVEELFGPEDYWCQCVAWS------SAGTTKSRKAHVRIAYLKKSFEQEPLGKEVSLEQEVLLQCRPPEGIPAAEVEWLKNEEVIDPAEDRNFYITIDHNLIIKQARLSDTANYTCVAKNIVAKRRSTTATVIVYVNGGWSTWTEW-----------SPCNSRCGRGFQKRTRSCTNPTPLNGGLPCDGQAIQKLPCTTLCTVDGVWTEWSKWSAC-GTECTQWRRRECNNPAPKNGGKDCEGLVLQSQNCTDGLCMQTAPS-----------------TDDVALYVGIVIAVIMCLVISVIVALFVYRKTHRDFDSDIIDTSALNGGFQ------SVNIKTARSADLLTAPPDLTNAAAMYRGPVY------------------ALHDVSDKI-----------PMTNSPLLDPL-PNLKIKVYNSSGLVT----PQDDLGGDFTSKLSPKITQSLLENSDTM-NLRNQSLARSRDPSCTAH---------GSFNSQGGHLIVPNSGVSLLVPAGAIPQGRVYEMCVTVHRKDSLRPPVEDIQTVLSPVVSCGPAGALLTRPVILTIHHCADNVQE-DWLIQLKNRLS----MGEWEDVV-VVGEENFTTPCYVQMDSEACHILTETLGTYCLVGQSI-GKAAAKRLKLAVFGPVSCTTLDYH-------IRVYCLDDTQDALKEVLQMET-QMGGKLLDEPKTLNFKDSTHNLRLSIHDVPHMQWKSKLIAKYQEIPFHQVWSGSQRSLHCTFT-LERLTPAT---MELS---------CKLCVRQVEGE--GQIFQLSN---TLEEELQCIDTSLMDPAS-----------NITTLTGPNAFRIPLSIRQKLCGSLDAPQTRGNDWRMLAHKLNLDRYLNYFATKSSPTGVILDLWEAQHFPDGDLNELAAVLEEMGRHD 911
BLAST of Unc-5 netrin receptor B vs. Ensembl Medaka
Match: si:ch73-72b7.1 (netrin receptor UNC5C [Source:NCBI gene;Acc:101174433]) HSP 1 Score: 288.886 bits (738), Expect = 5.842e-82 Identity = 267/1005 (26.57%), Postives = 429/1005 (42.69%), Query Frame = 3
Query: 369 EGVPKFIQQPKSMYYVSKSHPAVITCIAQPVSHVNIFCADKQYSYMNEEVSATGLKVIKMDNEGRLAVKGNRWKFSLEVQHKDVIEWFS--EYRCHCEAWNQIEQLQKVKKVESSSAVIYDSYINKDFKTVPKNQKVSVRGSVKLSCIPPDAKPPAEIHWVKNGEKITGKSHPQFEINEYGELLLSNIRLTDSGNYSCVASSFGLERHA-TAQILVFEVGQWSDWSEWTGICPNICSKGSNCPKVCSTSRQQRVRYCNQIK--NQKANCIGSEIEYKRCDLICDPN-LWTFWSEWSKCSGNPCKKERTRQCTT---NNCGKASS---VEIDNCTLAECGGFVASFINSNKKYPESSTSIYITHDVAMYIGLFVAVSVFLMVVAIIFCLIRRRVIGFSPNRVWRYSTTANGIQMFYPDXXXXXXXXXXXXXXXXXXDI-NQPSLYRSIVLPNSLPFLPSNQSDASSNSAYTDVGNDITYIQRNHLPSLPMIATPLLSSMKPTLKIRPSYSDSKVSSTLYPQMGLVKH-VSTLPIPVSSSLSDHYQELGNTDNETSDQSVTEPCLPYNFNGENMIWATIDSSGGRISLALSDINLTCPPNSFAPGISEPIFLATCNSEQDLPNLSANETLLSPVVVCGPTNVIAFKPFILNIPHCAYNTDSGNWAISVLTSYSPLKQKPYWQKYLDLDAEDKDSPPGYAQLAKDRLFLITNQLQRFCVVGSSYRNKRATKVLRIAAY----CTGLDRRHADEQIVVRLYLIPDIAECISKVHNFETNRLGARLVTNQKQFFCEDEAGNITVVISDLA-MDWQASSANNYQEIPFKDVWHSP--TLHCSFNFIKRLINANSSELKISVNSLDFNWFCTLSIYQTNSHHNKQTVLLSTPNGSSHTSISATSTQFSNYSAGGSQSFPYFVDDCSKTNFESVFKLPEQTKIKLCKLLDSLTPLDNDWRQLARHLSITRSLQFFSNKLSSTEILLDLWEAQNHSRKSLNNLIDILRKMGRLD 3320
E +P F+ +P+ Y V K+ P + C A P + + C + + V ++D L V+ + S+E+ + V E F +Y C C AW+ +S A + +Y+ K F+ P ++VS+ V L C PP+ P AE+ W+KN E I F I L++ RL+D+ NY+CVA + +R + TA ++V+ G WS W+EW S C C Q+R R C N C G I+ C +C + +WT WS+WS C G C + R R+C N GK ++ NCT C S T DVA+Y+G+ +AV + L++ I+ + R+ + + S G Q ++ + ++ D+ N ++YR V A DV + I PM +PLL + P LKI+ S V+ PQ L S L ++ SL ++ + N N++ +S C + + +S GG + + S ++L P + G + + + P + +T+LSPVV CGP + +P IL I HCA N +W I + S W+ + + E+ + P Y Q+ + ++T L +C+VG S K A K L++A + CT LD +R+Y + D + + +V ET ++G +L+ K +D N+ + I D+ M W++ YQEIPF VW +LHC+F ++RL A +++S C L + Q Q LS + + T + ++ + + + F++P + KLC LD+ NDWR LA L++ R L +F+ K S T ++LDLWEAQ+ LN L +L +MGR D
Sbjct: 62 EPLPHFLFEPEEGYIV-KNKPVNLYCKATPATQIYFKCNSEWVHQKDHTVEE------RVDENSGLVVR----EASIEITRQQVEELFGPEDYWCQCVAWS------SAGTTKSRKAHVRIAYLKKSFEQEPLGKEVSLEQEVLLQCRPPEGIPAAEVEWLKNEEVIDPAEDRNFYITIDHNLIIKQARLSDTANYTCVAKNIVAKRRSTTATVIVYVNGGWSTWTEW-----------SPCNSRCGRGFQKRTRSCTNPTPLNGGLPCDGQAIQKLPCTTLCTVDGVWTEWSKWSAC-GTECTQWRRRECNNPAPKNGGKDCEGLVLQSQNCTDGLCMQTAPS-----------------TDDVALYVGIVIAVIMCLVISVIVALFVYRKTHRDFDSDIIDTSALNGGFQ------SVNIKTARSADLLTAPPDLTNAAAMYRGPVY------------------ALHDVSDKI-----------PMTNSPLLDPL-PNLKIKVYNSSGLVT----PQDDLGGDFTSKLSPKITQSLLENSDTM-NLRNQSLARSRDPSCTAH---------GSFNSQGGHLIVPNSGVSLLVPAGAIPQGRVYEMCVTVHRKDSLRPPVEDIQTVLSPVVSCGPAGALLTRPVILTIHHCADNVQE-DWLIQLKNRLS----MGEWEDVV-VVGEENFTTPCYVQMDSEACHILTETLGTYCLVGQSI-GKAAAKRLKLAVFGPVSCTTLDYH-------IRVYCLDDTQDALKEVLQMET-QMGGKLLDEPKTLNFKDSTHNLRLSIHDVPHMQWKSKLIAKYQEIPFHQVWSGSQRSLHCTFT-LERLTPAT---MELS---------CKLCVRQVEGE--GQIFQLSN---TLEEELQCIDTSLMDPAS-----------NITTLTGPNAFRIPLSIRQKLCGSLDAPQTRGNDWRMLAHKLNLDRYLNYFATKSSPTGVILDLWEAQHFPDGDLNELAAVLEEMGRHD 926
BLAST of Unc-5 netrin receptor B vs. Ensembl Medaka
Match: unc5c (netrin receptor UNC5C [Source:NCBI gene;Acc:101157960]) HSP 1 Score: 288.5 bits (737), Expect = 8.741e-82 Identity = 256/1013 (25.27%), Postives = 435/1013 (42.94%), Query Frame = 3
Query: 369 EGVPKFIQQPKSMYYVSKSHPAVITCIAQPVSHVNIFCADKQYSYMNEEVSATGLKVIKMDNEGRLAVKGNRWKFSLEVQHKDVIEWFS--EYRCHCEAWNQIEQLQKVKKVESSSAVIYDSYINKDFKTVPKNQKVSVRGSVKLSCIPPDAKPPAEIHWVKNGEKITGKSHPQFEINEYGELLLSNIRLTDSGNYSCVASSFGLERHA-TAQILVFEVGQWSDWSEWTGICPNICSKGSNCPKVCSTSRQQRVRYCNQIK--NQKANCIGSEIEYKRCDLICDPN-LWTFWSEWSKCSGNPCKKERTRQCTT---NNCGK---ASSVEIDNCTLAECGGFVASFINSNKKYPESSTSIY-----ITHDVAMYIGLFVAVSVFLMVVAIIFCLIRRRVIGFSPNRVWRYSTTANGIQMFYPDXXXXXXXXXXXXXXXXXXDI-NQPSLYRSIVLPNSLPFLPSNQSDASSNSAYTDVGNDITYIQRNHLPSLPMIATPLLSSMKPTLKIRPSYSDSKVSSTLYPQMGLVKHVSTLPIPVSSSLSDHYQE--LGNTDNETSDQSVTEPCLPYNFNGENMIWATIDSSGGRISLALSDINLTCPPNSFAPGISEPIFLATCNSEQDLPNLSANETLLSPVVVCGPTNVIAFKPFILNIPHCAYNTDSGNWAISVLTSYSPLKQKPYWQKYLDLDAEDKDSPPGYAQLAKDRLFLITNQLQRFCVVGSSYRNKRATKVLRIAAY----CTGLDRRHADEQIVVRLYLIPDIAECISKVHNFETNRLGARLVTNQKQFFCEDEAGNITVVISDLA-MDWQASSANNYQEIPFKDVWHSP--TLHCSFNFIKRLINANSSELKISVNSLDFNWFCTLSIYQTNSHHN--KQTVLLSTPNGSSHTSISATSTQFSNYSAGGSQSFPYFVDDCSKTNFESVFKLPEQTKIKLCKLLDSLTPLDNDWRQLARHLSITRSLQFFSNKLSSTEILLDLWEAQNHSRKSLNNLIDILRKMGRLD 3320
E +P F+ +P+ Y V K+ P + C A P + + C + ++ + E ++D L V+ + S+E+ + V E F ++ C C AW+ +S A + +Y+ K F P ++VS+ V L C PP+ PPAE+ W+KN E I F I L++ RL+D+ NY+CVA + +R++ TA ++V+ G WS W+EW+ +C + C +G Q+R R C N A C G I+ C+ +C + LWT WS+WS C G C R R C N GK + ++ NCT C + S +N + + T DVA+Y+G+ +AV + L++ ++ + RR + + S G Q + + ++ D+ + +LYR V A DV + I PM +PLL + P LKI+ +Y GLV L SS LS L N+D+ ++ ++ L + + S GG++ + S ++L P + G +++ E P++ +T+LSPVV CGP + +P ++ + HCA +W I + + Q+ W+ + + E+ + P Y Q+ + ++T L +C+VG S + K L++A + C ++ +R+Y + D + + +V E ++G +L+ K +D N+ + I D+ M W++ YQE+ F+ VW LHC F + S +++D C + + Q + LS + S TS+ ++ + + F++P + KLC LD+ NDWR LA L++ R L +F+ K S T ++LDLWEAQ+ +L+ L +L +MGR D
Sbjct: 41 EPLPVFLMEPEEAYIV-KNKPVNLYCKATPATQIYFKC-NSEWVHQKEHTVEE-----RVDENSGLVVR----EASIEITRQQVEELFGPEDFWCQCVAWS------SAGTTKSRKAHVRIAYLRKPFDQEPLGKEVSIEQEVLLQCRPPEGIPPAEVEWLKNDEIIDPAEDRNFYITIDHNLIIKQARLSDTANYTCVAKNIVAKRYSTTATVIVYVNGGWSTWTEWS-VCNSRCGRG----------YQKRTRSCTNPAPLNGGAICDGQGIQKLPCNPLCPVDGLWTEWSKWSTC-GTECTHWRRRDCGAPAPKNGGKDCEGTVLQSKNCTDGLC---MQSSLNPKSSEAKGKNDLGNSLAPSTDDVALYVGIVIAVIMCLVISVVVALFVYRRNHRDFSSDILDSSALNGGFQ------PVSIKTARKADLLTAPPDLTSAAALYRGPVY------------------ALHDVADKI-----------PMTNSPLLEPL-PNLKIK-----------VYNSSGLVTPQDDLGGEFSSKLSPKLPHCLLDNSDSTMGRRTQSQTLL-RTRDPSCTALGSFSSQGGQLIVPNSGVSLLIPAGAVPQGRVYEMYVTVQRKENLRPSVEDGQTVLSPVVSCGPPGALLTRPVVITMHHCAVCDGQQDWLIQLKSQ----SQQNQWEDVV-VVGEENFTTPCYVQMDDEACHILTETLGTYCLVGQSL-SAATIKRLKLAIFGPVTCAAMEYH-------IRVYCLDDTQDALKEVLQME-KQMGGKLLDEPKTLSFKDSTHNLRLSIHDVPHMMWKSKLLAKYQELSFQQVWSGSQRNLHCCFTL-----------ERFSTSTVDLT--CKICVRQVEGEGQIFQLDTTLSEDSQSIDTSLLDPASNITTLVG------------------PNAFRIPVSIRQKLCSSLDAPQTRGNDWRMLAHKLNLDRYLNYFATKSSPTGVILDLWEAQHFPDGNLSRLAQVLEEMGRHD 928
BLAST of Unc-5 netrin receptor B vs. Ensembl Medaka
Match: unc5c (netrin receptor UNC5C [Source:NCBI gene;Acc:101157960]) HSP 1 Score: 287.73 bits (735), Expect = 1.047e-81 Identity = 255/1008 (25.30%), Postives = 430/1008 (42.66%), Query Frame = 3
Query: 369 EGVPKFIQQPKSMYYVSKSHPAVITCIAQPVSHVNIFCADKQYSYMNEEVSATGLKVIKMDNEGRLAVKGNRWKFSLEVQHKDVIEWFS--EYRCHCEAWNQIEQLQKVKKVESSSAVIYDSYINKDFKTVPKNQKVSVRGSVKLSCIPPDAKPPAEIHWVKNGEKITGKSHPQFEINEYGELLLSNIRLTDSGNYSCVASSFGLERHA-TAQILVFEVGQWSDWSEWTGICPNICSKGSNCPKVCSTSRQQRVRYCNQIK--NQKANCIGSEIEYKRCDLICDPN-LWTFWSEWSKCSGNPCKKERTRQCTT---NNCGK---ASSVEIDNCTLAECGGFVASFINSNKKYPESSTSIYITHDVAMYIGLFVAVSVFLMVVAIIFCLIRRRVIGFSPNRVWRYSTTANGIQMFYPDXXXXXXXXXXXXXXXXXXDI-NQPSLYRSIVLPNSLPFLPSNQSDASSNSAYTDVGNDITYIQRNHLPSLPMIATPLLSSMKPTLKIRPSYSDSKVSSTLYPQMGLVKHVSTLPIPVSSSLSDHYQE--LGNTDNETSDQSVTEPCLPYNFNGENMIWATIDSSGGRISLALSDINLTCPPNSFAPGISEPIFLATCNSEQDLPNLSANETLLSPVVVCGPTNVIAFKPFILNIPHCAYNTDSGNWAISVLTSYSPLKQKPYWQKYLDLDAEDKDSPPGYAQLAKDRLFLITNQLQRFCVVGSSYRNKRATKVLRIAAY----CTGLDRRHADEQIVVRLYLIPDIAECISKVHNFETNRLGARLVTNQKQFFCEDEAGNITVVISDLA-MDWQASSANNYQEIPFKDVWHSP--TLHCSFNFIKRLINANSSELKISVNSLDFNWFCTLSIYQTNSHHN--KQTVLLSTPNGSSHTSISATSTQFSNYSAGGSQSFPYFVDDCSKTNFESVFKLPEQTKIKLCKLLDSLTPLDNDWRQLARHLSITRSLQFFSNKLSSTEILLDLWEAQNHSRKSLNNLIDILRKMGRLD 3320
E +P F+ +P+ Y V K+ P + C A P + + C + ++ + E ++D L V+ + S+E+ + V E F ++ C C AW+ +S A + +Y+ K F P ++VS+ V L C PP+ PPAE+ W+KN E I F I L++ RL+D+ NY+CVA + +R++ TA ++V+ G WS W+EW+ +C + C +G Q+R R C N A C G I+ C+ +C + LWT WS+WS C G C R R C N GK + ++ NCT C S T DVA+Y+G+ +AV + L++ ++ + RR + + S G Q + + ++ D+ + +LYR V A DV + I PM +PLL + P LKI+ +Y GLV L SS LS L N+D+ ++ ++ L + + S GG++ + S ++L P + G +++ E P++ +T+LSPVV CGP + +P ++ + HCA +W I + + Q+ W+ + + E+ + P Y Q+ + ++T L +C+VG S + K L++A + C ++ +R+Y + D + + +V E ++G +L+ K +D N+ + I D+ M W++ YQE+ F+ VW LHC F + S +++D C + + Q + LS + S TS+ ++ + + F++P + KLC LD+ NDWR LA L++ R L +F+ K S T ++LDLWEAQ+ +L+ L +L +MGR D
Sbjct: 41 EPLPVFLMEPEEAYIV-KNKPVNLYCKATPATQIYFKC-NSEWVHQKEHTVEE-----RVDENSGLVVR----EASIEITRQQVEELFGPEDFWCQCVAWS------SAGTTKSRKAHVRIAYLRKPFDQEPLGKEVSIEQEVLLQCRPPEGIPPAEVEWLKNDEIIDPAEDRNFYITIDHNLIIKQARLSDTANYTCVAKNIVAKRYSTTATVIVYVNGGWSTWTEWS-VCNSRCGRG----------YQKRTRSCTNPAPLNGGAICDGQGIQKLPCNPLCPVDGLWTEWSKWSTC-GTECTHWRRRDCGAPAPKNGGKDCEGTVLQSKNCTDGLCMQMAPS-----------------TDDVALYVGIVIAVIMCLVISVVVALFVYRRNHRDFSSDILDSSALNGGFQ------PVSIKTARKADLLTAPPDLTSAAALYRGPVY------------------ALHDVADKI-----------PMTNSPLLEPL-PNLKIK-----------VYNSSGLVTPQDDLGGEFSSKLSPKLPHCLLDNSDSTMGRRTQSQTLL-RTRDPSCTALGSFSSQGGQLIVPNSGVSLLIPAGAVPQGRVYEMYVTVQRKENLRPSVEDGQTVLSPVVSCGPPGALLTRPVVITMHHCAVCDGQQDWLIQLKSQ----SQQNQWEDVV-VVGEENFTTPCYVQMDDEACHILTETLGTYCLVGQSL-SAATIKRLKLAIFGPVTCAAMEYH-------IRVYCLDDTQDALKEVLQME-KQMGGKLLDEPKTLSFKDSTHNLRLSIHDVPHMMWKSKLLAKYQELSFQQVWSGSQRNLHCCFTL-----------ERFSTSTVDLT--CKICVRQVEGEGQIFQLDTTLSEDSQSIDTSLLDPASNITTLVG------------------PNAFRIPVSIRQKLCSSLDAPQTRGNDWRMLAHKLNLDRYLNYFATKSSPTGVILDLWEAQHFPDGNLSRLAQVLEEMGRHD 909
BLAST of Unc-5 netrin receptor B vs. Planmine SMEST
Match: SMESG000040323.1 (SMESG000040323.1) HSP 1 Score: 2125.13 bits (5505), Expect = 0.000e+0 Identity = 1045/1049 (99.62%), Postives = 1045/1049 (99.62%), Query Frame = 3
Query: 216 MKFQILLLAVFIIDRLISSLAQNGILTDWDSKENHEVDSKKDLVLPSEKHLEGVPKFIQQPKSMYYVSKSHPAVITCIAQPVSHVNIFCADKQYSYMNEEVSATGLKVIKMDNEGRLAVKGNRWKFSLEVQHKDVIEWFSEYRCHCEAWNQIEQLQKVKKVESSSAVIYDSYINKDFKTVPKNQKVSVRGSVKLSCIPPDAKPPAEIHWVKNGEKITGKSHPQFEINEYGELLLSNIRLTDSGNYSCVASSFGLERHATAQILVFEVGQWSDWSEWTGICPNICSKGSNCPKVCSTSRQQRVRYCNQIKNQKANCIGSEIEYKRCDLICDPNLWTFWSEWSKCSGNPCKKERTRQCTTNNCGKASSVEIDNCTLAECGGFVASFINSNKKYPESSTSIYITHDVAMYIGLFVAVSVFLMVVAIIFCLIRRRVIGFSPNRVWRYSTTANGIQMFYPDXXXXXXXXXXXXXXXXXXDINQPSLYRSIVLPNSLPFLPSNQSDASSNSAYTDVGNDITYIQRNHLPSLPMIATPLLSSMKPTLKIRPSYSDSKVSSTLYPQMGLVKHVSTLPIPVSSSLSDHYQELGNTDNETSDQSVTEPCLPYNFNGENMIWATIDSSGGRISLALSDINLTCPPNSFAPGISEPIFLATCNSEQDLPNLSANETLLSPVVVCGPTNVIAFKPFILNIPHCAYNTDSGNWAISVLTSYSPLKQKPYWQKYLDLDAEDKDSPPGYAQLAKDRLFLITNQLQRFCVVGSSYRNKRATKVLRIAAYCTGLDRRHADEQIVVRLYLIPDIAECISKVHNFETNRLGARLVTNQKQFFCEDEAGNITVVISDLAMDWQASSANNYQEIPFKDVWHSPTLHCSFNFIKRLINANSSELKISVNSLDFNWFCTLSIYQTNSHHNKQTVLLSTPNGSSHTSISATSTQFSNYSAGGSQSFPYFVDDCSKTNFESVFKLPEQTKIKLCKLLDSLTPLDNDWRQLARHLSITRSLQFFSNKLSSTEILLDLWEAQNHSRKSLNNLIDILRKMGRLDCVAILEKDLIQINA 3362
MKFQILL AVFIIDRLISSLAQNGILTDWDSKENHEVDSKKDLVLPSEKHLEGVPKFIQQPKSMYYVSKSHPAVITCIAQPVSHVNIFCADKQYSYMNEEVSATGLKVIKMDNEGRLAVKGNRWKFSLEVQHKDVIEWFSEYRCHCEAWNQIEQLQKVKKVESSSAVIYDSYINKDFKTVPKNQKVSVRGSVKLSCIPPDAKPPAEIHWVKNGEKITGKSHPQFEINEYGELLLSNIRLTDSGNYSCVASSFGLERHATAQILVFEVGQWSDWSEWTGICPNICSKGSNCPKVCSTSRQQRVRYCNQI NQKANCIGSEIEYKRCDLICD NLWTFWSEWSKCSGNPCKKERTRQCTTNNCGKASSVEIDNCTLAECGGFVASFINSNKKYPESSTSIYITHDVAMYIGLFVAVSVFLMVVAIIFCLIRRRVIGFSPNRVWRYSTTANGIQMFYPDKNLKKNLSNLSNKQINLIDINQPSLYRSIVLPNSLPFLPSNQSDASSNSAYTDVGNDITYIQRNHLPSLPMIATPLLSSMKPTLKIRPSYSDSKVSSTLYPQMGLVKHVSTLPIPVSSSLSDHYQELGNTDNETSDQSVTEPCLPYNFNGENMIWATIDSSGGRISLALSDINLTCPPNSFAPGISEPIFLATCNSEQDLPNLS NETLLSPVVVCGPTNVIAFKPFILNIPHCAYNTDSGNWAISVLTSYSPLKQKPYWQKYLDLDAEDKDSPPGYAQLAKDRLFLITNQLQRFCVVGSSYRNKRATKVLRIAAYCTGLDRRHADEQIVVRLYLIPDIAECISKVHNFETNRLGARLVTNQKQFFCEDEAGNITVVISDLAMDWQASSANNYQEIPFKDVWHSPTLHCSFNFIKRLINANSSELKISVNSLDFNWFCTLSIYQTNSHHNKQTVLLSTPNGSSHTSISATSTQFSNYSAGGSQSFPYFVDDCSKTNFESVFKLPEQTKIKLCKLLDSLTPLDNDWRQLARHLSITRSLQFFSNKLSSTEILLDLWEAQNHSRKSLNNLIDILRKMGRLDCVAILEKDLIQINA
Sbjct: 1 MKFQILLQAVFIIDRLISSLAQNGILTDWDSKENHEVDSKKDLVLPSEKHLEGVPKFIQQPKSMYYVSKSHPAVITCIAQPVSHVNIFCADKQYSYMNEEVSATGLKVIKMDNEGRLAVKGNRWKFSLEVQHKDVIEWFSEYRCHCEAWNQIEQLQKVKKVESSSAVIYDSYINKDFKTVPKNQKVSVRGSVKLSCIPPDAKPPAEIHWVKNGEKITGKSHPQFEINEYGELLLSNIRLTDSGNYSCVASSFGLERHATAQILVFEVGQWSDWSEWTGICPNICSKGSNCPKVCSTSRQQRVRYCNQINNQKANCIGSEIEYKRCDLICDSNLWTFWSEWSKCSGNPCKKERTRQCTTNNCGKASSVEIDNCTLAECGGFVASFINSNKKYPESSTSIYITHDVAMYIGLFVAVSVFLMVVAIIFCLIRRRVIGFSPNRVWRYSTTANGIQMFYPDKNLKKNLSNLSNKQINLIDINQPSLYRSIVLPNSLPFLPSNQSDASSNSAYTDVGNDITYIQRNHLPSLPMIATPLLSSMKPTLKIRPSYSDSKVSSTLYPQMGLVKHVSTLPIPVSSSLSDHYQELGNTDNETSDQSVTEPCLPYNFNGENMIWATIDSSGGRISLALSDINLTCPPNSFAPGISEPIFLATCNSEQDLPNLSTNETLLSPVVVCGPTNVIAFKPFILNIPHCAYNTDSGNWAISVLTSYSPLKQKPYWQKYLDLDAEDKDSPPGYAQLAKDRLFLITNQLQRFCVVGSSYRNKRATKVLRIAAYCTGLDRRHADEQIVVRLYLIPDIAECISKVHNFETNRLGARLVTNQKQFFCEDEAGNITVVISDLAMDWQASSANNYQEIPFKDVWHSPTLHCSFNFIKRLINANSSELKISVNSLDFNWFCTLSIYQTNSHHNKQTVLLSTPNGSSHTSISATSTQFSNYSAGGSQSFPYFVDDCSKTNFESVFKLPEQTKIKLCKLLDSLTPLDNDWRQLARHLSITRSLQFFSNKLSSTEILLDLWEAQNHSRKSLNNLIDILRKMGRLDCVAILEKDLIQINA 1049
BLAST of Unc-5 netrin receptor B vs. Planmine SMEST
Match: SMESG000025091.1 (SMESG000025091.1) HSP 1 Score: 435.261 bits (1118), Expect = 3.339e-135 Identity = 331/1041 (31.80%), Postives = 501/1041 (48.13%), Query Frame = 3
Query: 318 HEVDSKKDLVLPSEKHLEGVPKFIQQPKSMYYVSKSHPAVITCIAQPVSHVNIFCADKQYSYMNEEVSATGLKVIKMD--NEGRLAVKGNRWKFSLEVQHKDVIEWFSEYRCHCEAWNQIEQLQKVKKVESSSAVIYDSYINKDFKTVPKNQKVSVRGSVKLSCIPPDAKPPAEIHWVKNGEKITGKSHPQFEINEYGELLLSNIRLTDSGNYSCVASSFGLERHATAQILVFE-------VGQWSDWSEWTGICPNICSKGSNCPKVCSTSRQQRVRYCNQ--IKNQKANCIGSEIEYKR--CDLICDPNLWTFWSEWSKCSGNPCKKERTRQCTTNNCGKASSVEIDNCTLAECGGFVASFINSNKKYPESSTSIYITHDVAMYIGLFVAVSVFLMVVAIIFCLIRRRVIGFSPNRVWRYSTTANGIQMFYP------DXXXXXXXXXXXXXXXXXXDINQPSLYRSIVLPNSLPFLPSNQSDASSNSAYTDVGNDITYIQRNHLPSLPMIATPLLSSMKPTLKIRPSYSDSKVSSTLYPQMGLVKHVSTLPIPVSSSLSDHYQELGNTDNETSDQSVTEPCLPYNFNGENMIWATIDSSGGRISLALSDINLTCPPNSFAPGISEPIFLATCNSEQDLPNLSANETLLSPVVVCGPTNVIAFKPFILNIPHCAYNTDSGNWAISVLTSYSP-----LKQ---KPYWQKYLDLDAEDKDSPPGYAQLAKDRLFLITNQLQRFCVVGSSYRNKRATKVLRIAAYCTGLDRRHADEQIVVRLYLIPDIAECISKVHNFETNRLGARLVTNQKQFFCEDEAGNITVVISDLAMDWQASSANNYQEIPFKDVW---HSPTLHCSFNFIKRLINANSSELKISVNSLDFNWFCTLSIYQTNSHHNKQTVLLSTP--NGSSHTSISATSTQFSNYSAGGSQSFPYFVDDCSKTNFESVFKLPEQTKIKLCKLLDSLTPLDNDWRQLARHLSITRSLQFFSNKLSSTEILLDLWEAQNHSRKSLNNLIDILRKMGRLDCVAILEKD 3344
E++ + D V +E LEG+P FI++P+S+YYV + PA I CIA+PVSHVNI C + +SYM+ E+S + L+V KM+ NE L G+RW FSLE+ + V EWF+ + C CEAWNQI L+ KKV S VI ++Y +FK VP+++ V S+ L+C+PP++KP A++ W+KN +++ + + +I E +LL+ + LTDSGNYSC+A S +R++ I+ + QWS WS G C ++ R R CN + + +C E EY R + +PN N SS++ G FVA + + V V + IIFCLIRR+ + RY NG + Y + + N +L ++ Q Y S PN P P+ S+ SS +AY+ G D +Y + PL+S+ S + S +S+T + L VS PI S S Y EL + D E+ S P + N + + W TI + GGR+ L S I LT P SF S ++LA ++ + P LS NETLL+P+V+ GP +V KP +L++PH A + GNW I +L+ P LK+ +P W+ + E D P Y L F++ +Q Q+ C+VG SY +ATK LR+AA+ L +R+Y+ D E V ET +LG+ L+ Q D GN+ I +L+ W++ YQEIPF+D+W S TLHC+F F N + S+ ++ C ++ YQ+ + KQ + + + S+H + YS + ++D +VF++ T+ KLC LLD++TP NDW+QL R LS+ L +F +K+S T+ L+ LWE++N + +L +LI L+ +GR DC +LE D
Sbjct: 34 REIEDENDFVKLNESKLEGIPSFIKEPESVYYVYEKKPAKIVCIAEPVSHVNIICNKEVFSYMDLELSESNLRVRKMNKNNEDDLT-NGHRWMFSLEITYNQVTEWFNTFSCVCEAWNQIPSLRLAKKVHSRYGVIKEAYFKSNFKKVPQSKTVVKGQSLILTCVPPESKPKAQVQWMKNKKRLFENN--RIKIVEEHQLLIEDTLLTDSGNYSCIAISLEEKRYSPIAIVKIQESVTENPATQWSAWSACDGNC-----------------KKTRTRNCNSKGVCKEIDSCTKKECEYNRAVAPFVKNPN--------------------------KNGVSTSSLQDARDIAMYVGLFVA-------------------------VTILVMV------ITIIFCLIRRKAL-LPLRSTMRYPLNINGNGVAYDVKNSLIKNSNTISTKNPYIMDTSLANLTQQRSYLSQSPPNLPP--PTCLSEISSTNAYS-TGIDFSYNSTGS----GKFSQPLISNSSSASTTNKSKATS-LSNTDHKPDPLT--VSGTPIN-SRPPSALYHEL-SLDRESICNS--PPFVSENIDISTLAWGTISTIGGRLCLPQSGITLTIAPGSFINSSSSEMYLAVSRNDPNPPILSDNETLLTPIVLFGPKDVPILKPCVLSVPHSA-DLRQGNWVIRLLSCVLPDQNDELKEPLCQPIWKNIATIGCE-TDQTPIYTHLDPYAAFIMLDQPQKICLVGQSYPGGKATKRLRLAAFGRPLSTSSYLPNYNIRIYVFSDTKEAFESVSTIET-KLGSTLLDITYQIIFSDSMGNLFFCIEELSTGWKSQLTTKYQEIPFQDIWSGSQSETLHCAFTF----DNIDPSQQSLT---------CRITAYQSGFYSQKQVITIKQDKLDRSNHKRDLIQHEKVLLYSESNNT----YLDP-----LMTVFRISNATRKKLCFLLDNVTPRGNDWKQLCRQLSLNGYLNYFMSKVSPTDALVTLWESRNRNENALIDLIISLKAIGRTDCSTLLESD 957
BLAST of Unc-5 netrin receptor B vs. Planmine SMEST
Match: SMESG000073898.1 (SMESG000073898.1) HSP 1 Score: 324.709 bits (831), Expect = 2.097e-94 Identity = 180/427 (42.15%), Postives = 259/427 (60.66%), Query Frame = 3
Query: 321 EVDSKKDLVLPSEKHLEGVPKFIQQPKSMYYVSKSHPAVITCIAQPVSHVNIFCADKQYSYMNEEVSATGLKVIKMDNEGRLAVKGNRWKFSLEVQHKDVIEWFSEYRCHCEAWNQIEQLQKVKKVESSSAVIYDSYINKDFKTVPKNQKVSVRGSVKLSCIPPDAKPPAEIHWVKNGEKITGKSHPQFEINEYGELLLSNIRLTDSGNYSCVASSFGLERHATAQILVFEVGQWSDWSEWTGI--CPNICSKGSNC-PKVCSTSRQQRVRYC--NQIKNQKANCIGSEIEYKRCDLICDP--NLWTFWSEWSKCSGNPCKKERTRQCTTNNCGKASSVEIDNCTLAECGGFVASFINSNKKYPESSTSIYITHDVAMYIGLFVAVSVFLMVVAIIFCLIRRR-VIGFSPNRVWRYSTTANGIQMFY 1577
EVD KKDLV P+EKH +G+PKFI +P+ YYV+KSHPA I CIA+PVSHVNIFCADKQ+SYMN+E+S +GL V+KM+ + KG RWKFS V++KD+IEWFSEY+C+CEAWN+I + K KKV SS+A+I +SY +FK P N K++ + L C PPD+KP +++ W+KN E IT ++P I+EY L++ + +DSGNY+CVA S G+ + ++I V V +WS WT + CP IC C ++CS ++R+R+C + K NC G + E + CD+ C+ + W WS W+ C + R R+C + C +I NC+ A C + P+ S + + MY+ LF+ +S+ +++ II CLI ++ I P R +S NGI Y
Sbjct: 35 EVDGKKDLVQPNEKHYDGIPKFILEPQPFYYVNKSHPATIVCIAEPVSHVNIFCADKQFSYMNKELSESGLAVVKMNEFNQFDPKGKRWKFSYVVEYKDIIEWFSEYKCYCEAWNRIVSINKDKKVHSSAALIQESYFQNEFKVSPTNTKLNEGEKLVLLCTPPDSKPNSKVTWLKNKELITNSNYPLVTIDEYKRLIIQKVSKSDSGNYTCVAQSQGIVK--KSKIAVITVTMKYEWSAWTDLEACPLICHMEGKCIGELCSNRNRRRLRHCLFDGKKTDSGNCKGPQFENEPCDIGCEKYESKWNSWSLWTTICVPTCSQTRVRRCESGKCFGPKQ-QIRNCSQAIC------------QKPDPSL-LLESQSTTMYLSLFITISILFIIILIILCLITQKGYISLLPRRGMVFSNHNNGITKIY 445 HSP 2 Score: 202.216 bits (513), Expect = 6.305e-53 Identity = 133/453 (29.36%), Postives = 227/453 (50.11%), Query Frame = 3
Query: 2013 LPYNFNGENMIWATIDSSGGRISLALSDINLTCPPNSFAPGISEPIFLATCNSEQDLPNLSANETLLSPVVVCGPTNVIAFKPFILNIPHCAYNTDSGNWAISVLTS-YSPLKQKPYWQKYLDLDAEDKDSPPGYAQLAKDRLFLITNQLQRFCVVG--SSYRNKRATKVLRIAAYCTGLDRRHADEQIVVRLYLIPDIAECISKVHNFETNRLGARLVTNQKQFFCEDEAGNITVVISDLAMDWQASSANNYQEIPFKDVWHSPTLHCSFNFIKRLINANSSELKISVNSLD---FNWFCTLSIYQTNSHHNKQTVLLSTPNGSSHTSISATSTQFSNYSAGGSQSFPYFVDDCSKTNFESVFKLPEQTKIKLCKLLDSLTPLDNDWRQLARHLSITRSLQFFSNKLSSTEILLDLWEAQNHSRKSLNNLIDILRKMGRLDCVAILEKDLIQ 3353
LP + E + W TI ++GGR+ L S I+LT P + G SE +FLA C ++P + E LLSPV++CGP + KP IL IPHCA N +W I VL++ + + P W++ + ++ YAQL LI + LQ C+ G S + + LR+ A+ L ++ ++R++LIPD E I V E +L +L+ N K+ G+I + DL++ W+ + + Q + VW RL ++ + E+ I + +D + C +++ Q + N+ + + ++ S+ S + S SQ+ ++D ++VF+L T+ +L LLDS W+ LA H+ + +L +FS K S ++ LLDLWE++ ++ +LI+ILR +GR DC I+E+++++
Sbjct: 571 LPSDIELETVAWGTITAAGGRLCLPQSGISLTIPRGAIHHGNSEEMFLAVCRDHANIPVIDMMEMLLSPVILCGPPHTRLLKPIILTIPHCA-NIQCSDWNIRVLSARFQNSQIPPLWKELSTVRPVNRSDANVYAQLDSISAHLIVDHLQMVCITGCLSPLSDLSVSIRLRVLAFSLPLS---SEVDHLIRVHLIPDTKEAIENVIVSEL-KLNGQLLDNSKKLSFSSSGGDIAFCLDDLSLGWRCHANSKMQTFSYSSVW-------------RLNHSQNQEIHIQLEHVDPTRSGFSCNITVQQIDLPQNQAVIRVVKERALNNRSLVPISLDAQSVSREYSQA---YLDP-----LQTVFRLSSATRQQLWPLLDS------SWQTLANHMLLNGNLNYFSEKKSPSDALLDLWESRCREEGAIADLINILRVIGRNDCAMIVEQEILK 991
BLAST of Unc-5 netrin receptor B vs. Planmine SMEST
Match: SMESG000025091.1 (SMESG000025091.1) HSP 1 Score: 309.301 bits (791), Expect = 2.743e-89 Identity = 247/757 (32.63%), Postives = 365/757 (48.22%), Query Frame = 3
Query: 1155 NCIGSEIEYKRCDLIC--------DPNLWTFWSEWSKCSGNPCKKERTRQCTTNNCGKASSVEIDNCTLAECGGFVASFINSNKKYPESSTSIYITHDVAMYIGLFVAVSVFLMVVAIIFCLIRRRVIGFSPNRVWRYSTTANGIQMFYP------DXXXXXXXXXXXXXXXXXXDINQPSLYRSIVLPNSLPFLPSNQSDASSNSAYTDVGNDITYIQRNHLPSLPMIATPLLSSMKPTLKIRPSYSDSKVSSTLYPQMGLVKHVSTLPIPVSSSLSDHYQELGNTDNETSDQSVTEPCLPYNFNGENMIWATIDSSGGRISLALSDINLTCPPNSFAPGISEPIFLATCNSEQDLPNLSANETLLSPVVVCGPTNVIAFKPFILNIPHCAYNTDSGNWAISVLTSYSP-----LKQ---KPYWQKYLDLDAEDKDSPPGYAQLAKDRLFLITNQLQRFCVVGSSYRNKRATKVLRIAAYCTGLDRRHADEQIVVRLYLIPDIAECISKVHNFETNRLGARLVTNQKQFFCEDEAGNITVVISDLAMDWQASSANNYQEIPFKDVW---HSPTLHCSFNFIKRLINANSSELKISVNSLDFNWFCTLSIYQTNSHHNKQTVLLSTP--NGSSHTSISATSTQFSNYSAGGSQSFPYFVDDCSKTNFESVFKLPEQTKIKLCKLLDSLTPLDNDWRQLARHLSITRSLQFFSNKLSSTEILLDLWEAQNHSRKSLNNLIDILRKMGRLDCVAILEKD 3344
+CI +E KR I N T WS WS C GN CKK RTR C + K EID+CT EC S++S+ D+AMY+GLFVAV++ +MV+ IIFCLIRR+ + RY NG + Y + + N +L ++ Q Y S PN P P+ S+ SS +AY+ G D +Y + PL+S+ S + S +S+T + L VS PI S S Y EL + D E+ S P + N + + W TI + GGR+ L S I LT P SF S ++LA ++ + P LS NETLL+P+V+ GP +V KP +L++PH A + GNW I +L+ P LK+ +P W+ + E D P Y L F++ +Q Q+ C+VG SY +ATK LR+AA+ L +R+Y+ D E V ET +LG+ L+ Q D GN+ I +L+ W++ YQEIPF+D+W S TLHC+F F N + S+ ++ C ++ YQ+ + KQ + + + S+H + YS + ++D +VF++ T+ KLC LLD++TP NDW+QL R LS+ L +F +K+S T+ L+ LWE++N + +L +LI L+ +GR DC +LE D
Sbjct: 244 SCIAISLEEKRYSPIAIVKIQESVTENPATQWSAWSACDGN-CKKTRTRNCNSKGVCK----EIDSCTKKECE--------------LSTSSLQDARDIAMYVGLFVAVTILVMVITIIFCLIRRKAL-LPLRSTMRYPLNINGNGVAYDVKNSLIKNSNTISTKNPYIMDTSLANLTQQRSYLSQSPPNLPP--PTCLSEISSTNAYS-TGIDFSYNSTGS----GKFSQPLISNSSSASTTNKSKATS-LSNTDHKPDPLT--VSGTPIN-SRPPSALYHEL-SLDRESICNS--PPFVSENIDISTLAWGTISTIGGRLCLPQSGITLTIAPGSFINSSSSEMYLAVSRNDPNPPILSDNETLLTPIVLFGPKDVPILKPCVLSVPHSA-DLRQGNWVIRLLSCVLPDQNDELKEPLCQPIWKNIATIGCE-TDQTPIYTHLDPYAAFIMLDQPQKICLVGQSYPGGKATKRLRLAAFGRPLSTSSYLPNYNIRIYVFSDTKEAFESVSTIET-KLGSTLLDITYQIIFSDSMGNLFFCIEELSTGWKSQLTTKYQEIPFQDIWSGSQSETLHCAFTFD----NIDPSQQSLT---------CRITAYQSGFYSQKQVITIKQDKLDRSNHKRDLIQHEKVLLYSESNNT----YLDP-----LMTVFRISNATRKKLCFLLDNVTPRGNDWKQLCRQLSLNGYLNYFMSKVSPTDALVTLWESRNRNENALIDLIISLKAIGRTDCSTLLESD 941 HSP 2 Score: 217.624 bits (553), Expect = 6.463e-58 Identity = 111/269 (41.26%), Postives = 166/269 (61.71%), Query Frame = 3
Query: 318 HEVDSKKDLVLPSEKHLEGVPKFIQQPKSMYYVSKSHPAVITCIAQPVSHVNIFCADKQYSYMNEEVSATGLKVIKMD--NEGRLAVKGNRWKFSLEVQHKDVIEWFSEYRCHCEAWNQIEQLQKVKKVESSSAVIYDSYINKDFKTVPKNQKVSVRGSVKLSCIPPDAKPPAEIHWVKNGEKITGKSHPQFEINEYGELLLSNIRLTDSGNYSCVASSFGLERHATAQILVFE-------VGQWSDWSEWTGICPNICSKGSNCPKVC 1097
E++ + D V +E LEG+P FI++P+S+YYV + PA I CIA+PVSHVNI C + +SYM+ E+S + L+V KM+ NE L G+RW FSLE+ + V EWF+ + C CEAWNQI L+ KKV S VI ++Y +FK VP+++ V S+ L+C+PP++KP A++ W+KN +++ + + +I E +LL+ + LTDSGNYSC+A S +R++ I+ + QWS WS G C ++ N VC
Sbjct: 34 REIEDENDFVKLNESKLEGIPSFIKEPESVYYVYEKKPAKIVCIAEPVSHVNIICNKEVFSYMDLELSESNLRVRKMNKNNEDDLT-NGHRWMFSLEITYNQVTEWFNTFSCVCEAWNQIPSLRLAKKVHSRYGVIKEAYFKSNFKKVPQSKTVVKGQSLILTCVPPESKPKAQVQWMKNKKRLFENN--RIKIVEEHQLLIEDTLLTDSGNYSCIAISLEEKRYSPIAIVKIQESVTENPATQWSAWSACDGNCKKTRTRNCNSKGVC 299
BLAST of Unc-5 netrin receptor B vs. Planmine SMEST
Match: SMESG000000615.1 (SMESG000000615.1) HSP 1 Score: 267.314 bits (682), Expect = 2.866e-74 Identity = 274/1058 (25.90%), Postives = 458/1058 (43.29%), Query Frame = 3
Query: 378 PKFIQQPKSMYYVSKSHPAVITCIAQPVSHVNIFCADKQ--------YSYMNEEVSATGLKVIKMDNEGRL-----AVKGNRWKFSLEVQHKDVIEWF-SEYRCHCEAWNQIEQLQKVKKVESSSAVIYDSYINKDFKTVPKNQKVSVRGSVKLSCIPPDAKPPAEIHWVKNGEKITGKSHPQFEINEYGELLLSNIRLTDSGNYSCVA-SSFGLERHATAQILVF-----EVGQWSDWSEWTGICPNICSKGSNCPKVCSTSRQQRVRYCNQIKNQKANCIGSEIEYKRCDLICDPN-LWTFWSEWSKCSGNPCKKERTRQCTT-------NNC-GKASSVEIDNCTLAECGGFVASFINSNKKYPE-SSTSIYITHDVAMYIGLFVAVSVFLMVVAIIFCLIRRRVIGFSPNRVWRYSTTANGIQ-MFYPDXXXXXXXXXXXXXXXXXXDINQPSL--YRSIVLPNSLPFL-PSNQSDASSNSAYTD---VGNDITYIQRNHLPSLPMIATPLLSSMKPTLKIRPSYSDSKVSSTLYPQMGLVKHVSTLPIPVSSSLSDH----YQELGNTDNETSDQSVTEPCLPYNFN------GENMIWATIDSSGGRISLALSDINLTCPPNSFAPGISEPIFLATCNSEQDLPNLSANETLLSPVVVCGPTNVIAF-KPFILNIPHCAYNTDSGNWAISVLTSYSPLKQKPYWQKYLDLDAEDKDSPPGYAQLAKDRLFLITNQLQRFCVVGS-----SYRNKR--------------ATKVLRIAAYCTGLDRRHADEQIVVRLYLIPDIAE----CISKVHNFETNRLGARLVTNQKQFFCEDEAGNITVVISDLAMDWQASSANNYQEIPFKDVWHSPTLHCSFNFIKRLINANSSELKISVNSLDFNWFCTLSIYQTNSHHNKQTVLLSTPNGSSHTSISATSTQFSNYSAGGSQSFPYFVDDCSKTNFESVFKLPEQTKIKLCKLLDSLTPLDNDWRQLARHLSITRSLQFFSNKLSSTEILLDLWEAQNHSRKSLNNLIDILRKMGRLDCVAILE 3338
P F++ P YV+ S +I C+ + S + I C + Q S +++ LK K ++ + +V+G+ +L + K V WF + C CEA + + V + I +YI+K FK P + + + VKL+CIPPD P +IHW KNG K+ + +++ G L++ + +TD+G Y CVA + G+ A++ V E G W W+ W CPN C+ G C C ++R R C + C GS ++ + C C + W WS WS C + C ++R R+C + C K S E +NCTL C S + N + + + Y+ D+ +Y+ L +A+ + ++V II C ++ + +ST +N I DK L +L NK + D N S+ Y S NS P + +N SSNS V N LS++ TLK P+ SK S +P + H + +P S L+++ YQ + ++ P + N N G N++ I +SGGR+ L + I++T P++F + + L + ++ + L S T LS ++ C I+ KP IL PHC +W + V+ + K W+ Y+D + Y L ++ +L+T +L FC++G SY NK A K L + ++ L+ H +Q+ + YL D + ISK+ G R+ ++ A N++V + + W+ + + YQEI F+D+W+ T FI R I SE ++ + +++YQ N + ++ + +S + +++ +ST S Y + P SKT F+LP T +L LD + W +A+ L I+ +L++F + + T LL LWEAQN +L +L L+ +G LD + +
Sbjct: 32 PIFVKMPPEHLYVTPSKAVMIECVVKQSSFLQINCVEDQDTISKTSTASLLDQSKETVYLKPNKKSDKKQFDKITKSVQGDVHSVNLTLTEKTVESWFVRNFWCQCEAAYTQDSSTSNQLVRTKKTFIEVAYIDKTFKLEPNSATLYLGRYVKLTCIPPDGSPKPKIHWRKNGRKLELTDLSKILVSDDGSLVIFSTSITDNGQYECVAENEAGIRISKAAKLEVLDTDSTENGDWLPWAPWNA-CPNDCTYGKYCVDSCIKYLRRRSRLCKTSSKDRVKCPGSSLQTESCATFCRVDGEWNTWSGWSLCQPD-CTRKRIRECNNPKPQSGGDQCLPKNSFSEKENCTLDSCFRIDKSKFSENIEIRSPNPQNRYVLRDMVVYVVLSIALFLLILVTTIILCFQKKHFL---------FSTQSNEINSKIGGDKGGFILLKSLGNKNAIVKDNNSESVTTYNSGSGNNSSPLINEANMKHDSSNSTICTSRFVDN--------------------LSTVDVTLKNTPA---SKQVSFQHPPISC--HYKEVELPTSPILANYPSLIYQPIST--------PISLPPIIENRNLISNGSGSNLL---ISNSGGRVILGSTGISVTVMPDTFGSEKTISMELYSKHTHERLIEFS-KYTQLSSIIFCSLKETISLQKPLILVFPHCVTWKSFSSWDMKVVKMNNNFK----WEVYIDFQNPQMSNKQAYCHLDEEFCYLMTFELFPFCLLGKSQNPLSYDNKDNFDLSNQFPLPVFLADKRLCVISF---LEPLHQQKQLQLSCYLFIDTKDIKDYLISKI-----TAAGCRIFDIPHILSLKESAANVSVTVESASTSWKVHAKHRYQEILFEDLWNFRTEP----FITRNIILEHSE------TIFQPFIGHITVYQNNFYQDRIEISVSFNSTEISNTLNKSSTPSSTYKDATCKLIP-----ASKT-----FRLPRVTIRELSIHLDPPKIPVSQWSMIAKQLGISNNLEYFHRQSNPTAYLLMLWEAQNREETALVDLKSTLKIIGLLDIANVFK 1009 The following BLAST results are available for this feature:
BLAST of Unc-5 netrin receptor B vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99) Total hits: 5
BLAST of Unc-5 netrin receptor B vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99) Total hits: 5
BLAST of Unc-5 netrin receptor B vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99) Total hits: 5
BLAST of Unc-5 netrin receptor B vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99) Total hits: 5
BLAST of Unc-5 netrin receptor B vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99) Total hits: 5
BLAST of Unc-5 netrin receptor B vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99) Total hits: 5
BLAST of Unc-5 netrin receptor B vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt) Total hits: 5
BLAST of Unc-5 netrin receptor B vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL) Total hits: 5
BLAST of Unc-5 netrin receptor B vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99) Total hits: 5
BLAST of Unc-5 netrin receptor B vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99) Total hits: 5
BLAST of Unc-5 netrin receptor B vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46) Total hits: 0
BLAST of Unc-5 netrin receptor B vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46) Total hits: 5
BLAST of Unc-5 netrin receptor B vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99) Total hits: 5
BLAST of Unc-5 netrin receptor B vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST) Total hits: 5
Analyses
This transcript is derived from or has results from the following analyses Sequences
The following sequences are available for this feature:
transcript sequence >SMED30013824 ID=SMED30013824|Name=Unc-5 netrin receptor B|organism=Schmidtea mediterranea sexual|type=transcript|length=3424bpback to top protein sequence of SMED30013824-orf-1 >SMED30013824-orf-1 ID=SMED30013824-orf-1|Name=SMED30013824-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=1050bp MKFQILLLAVFIIDRLISSLAQNGILTDWDSKENHEVDSKKDLVLPSEKHback to top Annotated Terms
The following terms have been associated with this transcript:
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
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