Protein CLP1 homolog

Overview
NameProtein CLP1 homolog
Smed IDSMED30013758
Length (bp)1360
Neoblast Clusters

Zeng et. al., 2018



▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)



Explore this single cell expression dataset with our NB Cluster Shiny App



 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of Protein CLP1 homolog (SMED30013758) t-SNE clustered cells

Violin plots show distribution of expression levels for Protein CLP1 homolog (SMED30013758) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of Protein CLP1 homolog (SMED30013758) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for Protein CLP1 homolog (SMED30013758) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020



SMED30013758

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 5

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
X1 cellSMED30013758SMESG000047440.1 SMESG000028257.1 SmedASXL_008948SmedAsxl_ww_GCZZ01PMID:26114597
Zhu et al., 2015		FACS sorted cell population asexual adult RNA-sequencing evidence
X2 cellSMED30013758SMESG000047440.1 SMESG000028257.1 SmedASXL_008948SmedAsxl_ww_GCZZ01PMID:26114597
Zhu et al., 2015		FACS sorted cell population asexual adult RNA-sequencing evidence
nervous systemSMED30013758SMESG000047440.1 SMESG000028257.1 dd_Smed_v4_5796_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
cephalic gangliaSMED30013758SMESG000047440.1 SMESG000028257.1 dd_Smed_v4_5796_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
non-ciliated neuronSMED30013758SMESG000047440.1 SMESG000028257.1 dd_Smed_v4_5796_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
[Close]
BLAST of Protein CLP1 homolog vs. Ensembl Human
Match: CLP1 (cleavage and polyadenylation factor I subunit 1 [Source:HGNC Symbol;Acc:HGNC:16999])

HSP 1 Score: 240.35 bits (612), Expect = 4.517e-74
Identity = 143/428 (33.41%), Postives = 237/428 (55.37%), Query Frame = 1 
Query:   67 TEVKLKAQQMMRFE--CTSVTIIKLVEGSAELFGTELSTKGALNLQQGFLGTILTFNGCTLKYTSNTIIQFTVGFNEDQELPNV-YLNFHAALEKIRNNANNDI-RGPRLMICGNESVGKTTLCRILSNYAARKYRKVILIDANVGMNDICLPGSIGALIVTKPYEVVEGWDIFEDPLIYSFGHLSPVENLKLFSLQLNNLAELVNIRSENDPEVFAGGCIINMSGVSKSDDSGESQKKGIEAIRAAISAFEVNLLIIIEDGFLENLLRKDLPDYVSVIRIPKSSGAHSRTPEQWQKERTSNIASYFHG-RGLHKLQPHKLTLLAENYKIYKIDLKKSTLALLPNDDTMEDEWCKLVEVPFSRSLSNRVLAVSEALDVDE-IPGAACYGFVVVLSVAPDNSSITVLSPGNDEPPNNILVMTDIQYVDM 1332
            T+ +L+ +  +RFE   +    ++L+ G AE+FGTEL+         G    + T++GC+++ +  T + +       ++ P + YLN H ALE++R  A  +  RGPR+M+ G   VGK+T+CR+L NYA R  R+   ++ +VG   + +PG++GAL + +P +V EG+ I + PL+Y FG  +P  N+KL++   + LA++ N R E +      GC+IN  G  K          G +A+  A SAFEV+++++++   L N L++DLP +V  + +PKS G   R+ +  ++ R   I  YF+G RG     PH   +   + KIYK+       + LP   + ED   KLV V   R + + +L+VS A   +E +   +  GF+VV SV  ++   TVLSP     P N L++ DI+++D+
Sbjct:   13 TKFELERETELRFEVEASQSVQLELLTGMAEIFGTELTRNKKFTFDAGAKVAVFTWHGCSVQLSGRTEVAYV-----SKDTPMLLYLNTHTALEQMRRQAEKEEERGPRVMVVGPTDVGKSTVCRLLLNYAVRLGRRPTYVELDVGQGSVSIPGTMGALYIERPADVEEGFSI-QAPLVYHFGSTTPGTNIKLYNKITSRLADVFNQRCEVNRRASVSGCVINTCGWVKGS--------GYQALVHAASAFEVDVVVVLDQERLYNELKRDLPHFVRTVLLPKSGGVVERSKDFRRECRDERIREYFYGFRGC--FYPHAFNVKFSDVKIYKVGAPTIPDSCLPLGMSQEDNQLKLVPVTPGRDMVHHLLSVSTAEGTEENLSETSVAGFIVVTSVDLEHQVFTVLSPAPRPLPKNFLLIMDIRFMDL 424
[Close]
BLAST of Protein CLP1 homolog vs. Ensembl Human
Match: CLP1 (cleavage and polyadenylation factor I subunit 1 [Source:HGNC Symbol;Acc:HGNC:16999])

HSP 1 Score: 240.35 bits (612), Expect = 4.517e-74
Identity = 143/428 (33.41%), Postives = 237/428 (55.37%), Query Frame = 1 
Query:   67 TEVKLKAQQMMRFE--CTSVTIIKLVEGSAELFGTELSTKGALNLQQGFLGTILTFNGCTLKYTSNTIIQFTVGFNEDQELPNV-YLNFHAALEKIRNNANNDI-RGPRLMICGNESVGKTTLCRILSNYAARKYRKVILIDANVGMNDICLPGSIGALIVTKPYEVVEGWDIFEDPLIYSFGHLSPVENLKLFSLQLNNLAELVNIRSENDPEVFAGGCIINMSGVSKSDDSGESQKKGIEAIRAAISAFEVNLLIIIEDGFLENLLRKDLPDYVSVIRIPKSSGAHSRTPEQWQKERTSNIASYFHG-RGLHKLQPHKLTLLAENYKIYKIDLKKSTLALLPNDDTMEDEWCKLVEVPFSRSLSNRVLAVSEALDVDE-IPGAACYGFVVVLSVAPDNSSITVLSPGNDEPPNNILVMTDIQYVDM 1332
            T+ +L+ +  +RFE   +    ++L+ G AE+FGTEL+         G    + T++GC+++ +  T + +       ++ P + YLN H ALE++R  A  +  RGPR+M+ G   VGK+T+CR+L NYA R  R+   ++ +VG   + +PG++GAL + +P +V EG+ I + PL+Y FG  +P  N+KL++   + LA++ N R E +      GC+IN  G  K          G +A+  A SAFEV+++++++   L N L++DLP +V  + +PKS G   R+ +  ++ R   I  YF+G RG     PH   +   + KIYK+       + LP   + ED   KLV V   R + + +L+VS A   +E +   +  GF+VV SV  ++   TVLSP     P N L++ DI+++D+
Sbjct:   13 TKFELERETELRFEVEASQSVQLELLTGMAEIFGTELTRNKKFTFDAGAKVAVFTWHGCSVQLSGRTEVAYV-----SKDTPMLLYLNTHTALEQMRRQAEKEEERGPRVMVVGPTDVGKSTVCRLLLNYAVRLGRRPTYVELDVGQGSVSIPGTMGALYIERPADVEEGFSI-QAPLVYHFGSTTPGTNIKLYNKITSRLADVFNQRCEVNRRASVSGCVINTCGWVKGS--------GYQALVHAASAFEVDVVVVLDQERLYNELKRDLPHFVRTVLLPKSGGVVERSKDFRRECRDERIREYFYGFRGC--FYPHAFNVKFSDVKIYKVGAPTIPDSCLPLGMSQEDNQLKLVPVTPGRDMVHHLLSVSTAEGTEENLSETSVAGFIVVTSVDLEHQVFTVLSPAPRPLPKNFLLIMDIRFMDL 424
[Close]
BLAST of Protein CLP1 homolog vs. Ensembl Human
Match: CLP1 (cleavage and polyadenylation factor I subunit 1 [Source:HGNC Symbol;Acc:HGNC:16999])

HSP 1 Score: 240.35 bits (612), Expect = 5.467e-74
Identity = 143/428 (33.41%), Postives = 237/428 (55.37%), Query Frame = 1 
Query:   67 TEVKLKAQQMMRFE--CTSVTIIKLVEGSAELFGTELSTKGALNLQQGFLGTILTFNGCTLKYTSNTIIQFTVGFNEDQELPNV-YLNFHAALEKIRNNANNDI-RGPRLMICGNESVGKTTLCRILSNYAARKYRKVILIDANVGMNDICLPGSIGALIVTKPYEVVEGWDIFEDPLIYSFGHLSPVENLKLFSLQLNNLAELVNIRSENDPEVFAGGCIINMSGVSKSDDSGESQKKGIEAIRAAISAFEVNLLIIIEDGFLENLLRKDLPDYVSVIRIPKSSGAHSRTPEQWQKERTSNIASYFHG-RGLHKLQPHKLTLLAENYKIYKIDLKKSTLALLPNDDTMEDEWCKLVEVPFSRSLSNRVLAVSEALDVDE-IPGAACYGFVVVLSVAPDNSSITVLSPGNDEPPNNILVMTDIQYVDM 1332
            T+ +L+ +  +RFE   +    ++L+ G AE+FGTEL+         G    + T++GC+++ +  T + +       ++ P + YLN H ALE++R  A  +  RGPR+M+ G   VGK+T+CR+L NYA R  R+   ++ +VG   + +PG++GAL + +P +V EG+ I + PL+Y FG  +P  N+KL++   + LA++ N R E +      GC+IN  G  K          G +A+  A SAFEV+++++++   L N L++DLP +V  + +PKS G   R+ +  ++ R   I  YF+G RG     PH   +   + KIYK+       + LP   + ED   KLV V   R + + +L+VS A   +E +   +  GF+VV SV  ++   TVLSP     P N L++ DI+++D+
Sbjct:   24 TKFELERETELRFEVEASQSVQLELLTGMAEIFGTELTRNKKFTFDAGAKVAVFTWHGCSVQLSGRTEVAYV-----SKDTPMLLYLNTHTALEQMRRQAEKEEERGPRVMVVGPTDVGKSTVCRLLLNYAVRLGRRPTYVELDVGQGSVSIPGTMGALYIERPADVEEGFSI-QAPLVYHFGSTTPGTNIKLYNKITSRLADVFNQRCEVNRRASVSGCVINTCGWVKGS--------GYQALVHAASAFEVDVVVVLDQERLYNELKRDLPHFVRTVLLPKSGGVVERSKDFRRECRDERIREYFYGFRGC--FYPHAFNVKFSDVKIYKVGAPTIPDSCLPLGMSQEDNQLKLVPVTPGRDMVHHLLSVSTAEGTEENLSETSVAGFIVVTSVDLEHQVFTVLSPAPRPLPKNFLLIMDIRFMDL 435
[Close]
BLAST of Protein CLP1 homolog vs. Ensembl Human
Match: CLP1 (cleavage and polyadenylation factor I subunit 1 [Source:HGNC Symbol;Acc:HGNC:16999])

HSP 1 Score: 115.546 bits (288), Expect = 4.782e-28
Identity = 75/230 (32.61%), Postives = 120/230 (52.17%), Query Frame = 1 
Query:  649 NNLAELVNIRSENDPEVFAGGCIINMSGVSKSDDSGESQKKGIEAIRAAISAFEVNLLIIIEDGFLENLLRKDLPDYVSVIRIPKSSGAHSRTPEQWQKERTSNIASYFHG-RGLHKLQPHKLTLLAENYKIYKIDLKKSTLALLPNDDTMEDEWCKLVEVPFSRSLSNRVLAVSEALDVDE-IPGAACYGFVVVLSVAPDNSSITVLSPGNDEPPNNILVMTDIQYVDM 1332
            + LA++ N R E +      GC+IN  G  K          G +A+  A SAFEV+++++++   L N L++DLP +V  + +PKS G   R+ +  ++ R   I  YF+G RG     PH   +   + KIYK+       + LP   + ED   KLV V   R + + +L+VS A   +E +   +  GF+VV SV  ++   TVLSP     P N L++ DI+++D+
Sbjct:  141 SRLADVFNQRCEVNRRASVSGCVINTCGWVKGS--------GYQALVHAASAFEVDVVVVLDQERLYNELKRDLPHFVRTVLLPKSGGVVERSKDFRRECRDERIREYFYGFRGC--FYPHAFNVKFSDVKIYKVGAPTIPDSCLPLGMSQEDNQLKLVPVTPGRDMVHHLLSVSTAEGTEENLSETSVAGFIVVTSVDLEHQVFTVLSPAPRPLPKNFLLIMDIRFMDL 360

HSP 2 Score: 82.8037 bits (203), Expect = 1.139e-16
Identity = 45/131 (34.35%), Postives = 76/131 (58.02%), Query Frame = 1 
Query:   67 TEVKLKAQQMMRFE--CTSVTIIKLVEGSAELFGTELSTKGALNLQQGFLGTILTFNGCTLKYTSNTIIQFTVGFNEDQELPNV-YLNFHAALEKIRNNANNDI-RGPRLMICGNESVGKTTLCRILSNYA 447
            T+ +L+ +  +RFE   +    ++L+ G AE+FGTEL+         G    + T++GC+++ +  T + +       ++ P + YLN H ALE++R  A  +  RGPR+M+ G   VGK+T+CR+L NYA
Sbjct:   13 TKFELERETELRFEVEASQSVQLELLTGMAEIFGTELTRNKKFTFDAGAKVAVFTWHGCSVQLSGRTEVAYV-----SKDTPMLLYLNTHTALEQMRRQAEKEEERGPRVMVVGPTDVGKSTVCRLLLNYA 138
[Close]
BLAST of Protein CLP1 homolog vs. Ensembl Human
Match: CLP1 (cleavage and polyadenylation factor I subunit 1 [Source:HGNC Symbol;Acc:HGNC:16999])

HSP 1 Score: 73.9442 bits (180), Expect = 2.611e-15
Identity = 41/125 (32.80%), Postives = 71/125 (56.80%), Query Frame = 1 
Query:   67 TEVKLKAQQMMRFECTSVTIIKL--VEGSAELFGTELSTKGALNLQQGFLGTILTFNGCTLKYTSNTIIQFTVGFNEDQELPN-VYLNFHAALEKIRNNA-NNDIRGPRLMICGNESVGKTTLCR 429
            T+ +L+ +  +RFE  +   ++L  + G AE+FGTEL+         G    + T++GC+++ +  T + +       ++ P  +YLN H ALE++R  A   + RGPR+M+ G   VGK+T+CR
Sbjct:   13 TKFELERETELRFEVEASQSVQLELLTGMAEIFGTELTRNKKFTFDAGAKVAVFTWHGCSVQLSGRTEVAYV-----SKDTPMLLYLNTHTALEQMRRQAEKEEERGPRVMVVGPTDVGKSTVCR 132
[Close]
BLAST of Protein CLP1 homolog vs. Ensembl Celegans
Match: clpf-1 (pep chromosome:WBcel235:III:3397743:3400644:1 gene:WBGene00010304.1 transcript:F59A2.4a.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:clpf-1)

HSP 1 Score: 202.216 bits (513), Expect = 5.979e-60
Identity = 131/431 (30.39%), Postives = 221/431 (51.28%), Query Frame = 1 
Query:   70 EVKLKAQQMMRFEC--TSVTIIKLVEGSAELFGTELSTKGALNLQQGFLGTILTFNGCTLKYTSNTIIQFTVGFNEDQELPNV-YLNFHAALEKIRNNA-------NNDIRGPRLMICGNESVGKTTLCRILSNYAARKYRKVILIDANVGMNDICLPGSIGALIVTKPYEVVEGWDIFEDPLIYSFGHLSPVENLKLFSLQLNNLAELVNIRSENDPEVFAGGCIINMSGVSKSDDSGESQKKGIEAIRAAISAFEVNLLIIIEDGFLENLLRKDLPDYVSVIRIPKSSGAHSRTPEQWQKERTSNIASYFHGRGLHKLQPHKLTLLAENYKIYKIDLKKSTLALLPNDDTMEDEWCKLVEVPFSRSLSNRVLAVSEALDVDE-IPGAACYGFVVVLSVAPDNSSITVLSPGNDEPPNNILVMTDIQYVD 1329
            E  LK    +RF     S   ++LV+G AE+FGTEL                 T+ G T++    T   +       +  P V YLN HAA+E++R          +N  +GPRL++ G   VGKTT+ RIL NY+ R+ R  I ++ +VG N + +PG++ A++V K  +V++G++    P++++FGH SP  NL L+      +A  +N + + + E   GG IIN  G    +        G + I  A SAFEV+++I+++   L + L K+LP++V +  +PKS G   RT +   K R  N+  YF+G   + L P    +  ++  + KI  ++   + LP    +E+   KLV +  S  + + + A S +   DE +  +  +GF +V  V  +  ++++L P     P+ +LV +DI ++D
Sbjct:    8 EFVLKEDCELRFAAGDDSDVCLELVKGYAEIFGTELLLNKKYTFPAKSRVAAFTWKGATIELVGTTESAYVA-----ESTPMVIYLNIHAAMEEVRKKREEQAAGNSNKAKGPRLLLVGPTDVGKTTVSRILCNYSVRQGRTPIFVELDVGQNSVSVPGTVAAVLVQKTADVIDGFE-RNQPIVFNFGHTSPSANLSLYEALFKEMATTLNAQIQENDEAKIGGMIINTCGWVDGE--------GYKCIVKAASAFEVDVVIVLDHERLYSDLSKELPEFVRLTHVPKSGGVEQRTGQIRSKMRGENVHRYFYGTRANNLYPFTFDVSFDDVTLCKIGAEQLPDSCLPFGMEVENHETKLVIMEPSADIKHHLFAFSRSTKADENVLKSPVFGFCLVTEVDLEKRTMSILCP-QRTIPSKVLVFSDITHLD 423
[Close]
BLAST of Protein CLP1 homolog vs. Ensembl Fly
Match: cbc (gene:FBgn0033842 transcript:FBtr0087701)

HSP 1 Score: 192.971 bits (489), Expect = 2.140e-56
Identity = 136/433 (31.41%), Postives = 211/433 (48.73%), Query Frame = 1 
Query:   52 EATDWTEVKLKAQQMMRFECT---SVTIIKLVEGSAELFGTELSTKGALNLQQGFLGTILTFNGCTLKYTSNTIIQFTVGFNEDQELPNV-YLNFHAALEKIRNNANNDIR-GPRLMICGNESVGKTTLCRILSNYAARKYRKVILIDANVGMNDICLPGSIGALIVTKPYEVVEGWDIFEDPLIYSFGHLSPVENLKLFSLQLNNLAELVNIRSENDPEVFAGGCIINMSGVSKSDDSGESQKKGIEAIRAAISAFEVNLLIIIEDGFLENLLRKDLPDYVSVIRIPKSSGAHSRTPEQWQKERTSNIASYFHGRGLHKLQPHKLTLLAENYKIYKIDLKKSTLALLPNDDTMEDEWCKLVEVPFSRSLSNRVLAVSEALDV-DEIPGAACYGFVVVLSVAPDNSSITVLSPGNDE-PPNNILVMTDIQYVD 1329
            +  D+T   L++   +RFE     +  ++ LV G AELFGTEL  K       G    I T+ GC L  +    + +       +E P V Y+N HAALE+ R  A    R GP  M+ G   VGK+TLCRIL NYA R  R+ +  D +VG   I + GS+  +++ +P  V EG+     PL+Y FGH SP  N  L++  ++ +AE+      ++    + G IIN  G  K          G   +  A  A+    + +++   L N L +D+P  V V+ +PKS G   R+ E   + R   I  YF+G       P    +  ++ ++YKI       + +P     ED   K+V V  + +L + VLA+S A  V D++ G    GF  V  V  +  ++ +LSP     PPN +L+ +++Q++D
Sbjct:    5 QGKDYT---LESDSELRFEIEQKDAKVLVSLVSGFAELFGTELVKKKQYEFGVGAKVAIFTYQGCVLHVSGKMDVCYI-----SKETPMVQYVNCHAALEQFRMEAEEKDRYGPVAMVVGPMDVGKSTLCRILLNYAVRVGRRPLYADLDVGQGSIAISGSVATILIERPANVEEGFAK-TAPLVYHFGHKSPSGNSVLYNAVVSKMAEVTLQSLNSNKRTKSSGIIINTCGWVKGS--------GYAHLLHAAKAYGACAIFVLDQERLYNELLRDVPKGVHVVLLPKSGGVVERSKELRHEARDQRIKEYFYGNTRAPFYPFSFEVKFQDLRLYKIGAPPLPDSCMPIGMKAEDNKTKVVAVTPTPALIHHVLALSFAESVEDDVIGTNVAGFCCVTEVDMERQAVMLLSPQPRPLPPNALLLWSELQFMD 420
[Close]
BLAST of Protein CLP1 homolog vs. Ensembl Zebrafish
Match: clp1 (cleavage and polyadenylation factor I subunit 1 [Source:NCBI gene;Acc:565621])

HSP 1 Score: 231.491 bits (589), Expect = 9.218e-71
Identity = 141/433 (32.56%), Postives = 232/433 (53.58%), Query Frame = 1 
Query:   67 TEVKLKAQQMMRFECTSVTIIKL--VEGSAELFGTELSTKGALNLQQGFLGTILTFNGCTLKYTSNTIIQFTVGFNEDQELPNV-YLNFHAALEKIRNNANND-IRGPRLMICGNESVGKTTLCRILSNYAARKYRKVILIDANVGMNDICLPGSIGALIVTKPYEVVEGWDIFEDPLIYSFGHLSPVENLKLFSLQLNNLAELVNIRSENDPEVFAGGCIINMSGVSKSDDSGESQKKGIEAIRAAISAFEVNLLIIIEDGFLENLLRKDLPDYVSVIRIPKSSGAHSRTPEQWQKERTSNIASYFHGRGLHKLQPHKLTLLAENYKIYKIDLKKSTLALLPNDDTMEDEWCKLVEVPFSRSLSNRVLAVSEALDVDEI-------PGAACYGFVVVLSVAPDNSSITVLSPGNDEPPNNILVMTDIQYVDM 1332
            T   L  +  +RFE  +   ++L  + G AE+FG+EL+         G    + T+ GC +  +  T + +       ++ P + YLN HAALE++R  A  D  RGPR+M+ G   VGK+T+CR+L NYA R  R+  L++ +VG + + +PG++ AL + +P +V EG+ + + PL++ FG  +P  N+KL++   ++LA+  + R E +     GGCIIN  G  K          G +A+    SAF+V+++++++   L N L++DLP +V V+ +PKS G   R+ +  ++ R   I  YF+G       PH   +   + +IYKI       + LP   + +D   KLV V   R L++ VL+VS   D  E+          AC GF+VV +V      +TVLSP     P + L++ DI+++D+
Sbjct:   25 TRFDLDKETELRFEVEAGERVQLELLSGLAEIFGSELNRNKKYTFGPGSKIAVFTWQGCGVALSGKTEVAYV-----SKDTPMLLYLNTHAALEQMRRQAEKDNERGPRVMVVGPTDVGKSTVCRMLLNYAVRLGRRPTLVELDVGQSSVSVPGTMSALCIERPADVEEGFSV-QAPLVFHFGSTTPGTNIKLYNKLTSSLADAFSQRCEVNRRASVGGCIINTCGWVKG--------SGYQALVHCASAFQVDVVLVLDQERLYNELKRDLPHFVRVVLLPKSGGVVERSKDCRRETRDEKIREYFYGFRGTSFYPHAFDVRFSDVRIYKIGAPSIPDSCLPLGMSQDDTQLKLVPVSPGRDLTHHVLSVSSVDDEAEVGQSRGILESPAC-GFIVVTAVDTQAQVMTVLSPAPRPLPRHTLLIMDIRFIDL 442
[Close]
BLAST of Protein CLP1 homolog vs. Ensembl Xenopus
Match: clp1 (cleavage and polyadenylation factor I subunit 1 [Source:NCBI gene;Acc:493364])

HSP 1 Score: 229.18 bits (583), Expect = 9.615e-70
Identity = 138/429 (32.17%), Postives = 233/429 (54.31%), Query Frame = 1 
Query:   67 TEVKLKAQQMMRFEC--TSVTIIKLVEGSAELFGTELSTKGALNLQQGFLGTILTFNGCTLKYTSNTIIQFTVGFNEDQELPNVYLNFHAALEKIRNNANND-IRGPRLMICGNESVGKTTLCRILSNYAARKYRKVILIDANVGMNDICLPGSIGALIVTKPYEVVEGWDIFEDPLIYSFGHLSPVENLKLFSLQLNNLAELVNIRSENDPEVFAGGCIINMSGVSKSDDSGESQKKGIEAIRAAISAFEVNLLIIIEDGFLENLLRKDLPDYVSVIRIPKSSGAHSRTPEQWQKERTSNIASYFHG-RGLHKLQPHKLTLLAENYKIYKIDLKKSTLALLPNDDTMEDEWCKLVEVPFSRSLSNRVLAV---SEALDVDEIPGAACYGFVVVLSVAPDNSSITVLSPGNDEPPNNILVMTDIQYVDM 1332
            T+ +L+ +  +R E   T    ++LV G AE+FGTEL+         G    I T++GCT++   +  + +    + D  +  +YLN    LE++R  A  +  RGPR+++ G   VGK+TLCR+L NYA R+ R+  L++ +VG   + +PG++GAL V +P +V EG+   + PL+Y FG  +P  N+KL++   + LA + N+R +++      GC+IN  G  K          G +A+  A SAFEV+++++++   L N L +DLP +V  + +PKS GA  R+ E  ++ R   +  YF+G RG   L PH   +     ++YK+       + LP   + ED   KLV V   R +++ +L+V         + I   +  GF+V+  V  +  ++TVLSP     P  +L++ DI+++D+
Sbjct:   23 TKFELERETELRLEVEGTDPVRVELVSGLAEVFGTELTRNKKYTFPPGSRAAIFTWHGCTVQLWGSPDVAYV---SRDTPM-LLYLNTQVGLEQMRAQAEREGERGPRVLVAGPSDVGKSTLCRLLLNYAVRRGRRPTLVELDVGQGSVSVPGTVGALCVERPADVEEGFSA-QAPLVYHFGSTTPGTNIKLYNKLTSRLAHVFNLRCDSNRRASVSGCLINTCGWVKG--------SGYQALIHAASAFEVDVVLVLDQERLYNDLLRDLPHFVRTLLLPKSGGASERSKECRRESRDQRVREYFYGPRG--SLYPHAFEIKFSEVRVYKVGAPSIPDSCLPLGMSQEDNQLKLVPVTPGRDMAHHLLSVVPLDGGGAEEGIEERSVAGFIVITGVDTERQTLTVLSPAPRPLPKCVLLIMDIRFMDL 436
[Close]
BLAST of Protein CLP1 homolog vs. Ensembl Mouse
Match: Clp1 (CLP1, cleavage and polyadenylation factor I subunit [Source:MGI Symbol;Acc:MGI:2138968])

HSP 1 Score: 241.121 bits (614), Expect = 1.408e-74
Identity = 144/428 (33.64%), Postives = 237/428 (55.37%), Query Frame = 1 
Query:   67 TEVKLKAQQMMRFECTSVTIIKL--VEGSAELFGTELSTKGALNLQQGFLGTILTFNGCTLKYTSNTIIQFTVGFNEDQELPNV-YLNFHAALEKIRNNANNDI-RGPRLMICGNESVGKTTLCRILSNYAARKYRKVILIDANVGMNDICLPGSIGALIVTKPYEVVEGWDIFEDPLIYSFGHLSPVENLKLFSLQLNNLAELVNIRSENDPEVFAGGCIINMSGVSKSDDSGESQKKGIEAIRAAISAFEVNLLIIIEDGFLENLLRKDLPDYVSVIRIPKSSGAHSRTPEQWQKERTSNIASYFHG-RGLHKLQPHKLTLLAENYKIYKIDLKKSTLALLPNDDTMEDEWCKLVEVPFSRSLSNRVLAVSEALDVDE-IPGAACYGFVVVLSVAPDNSSITVLSPGNDEPPNNILVMTDIQYVDM 1332
            T+ +L+ +  +RFE  +   ++L  + G AE+FGTEL+         G    + T++GC+L+ +  T + +       ++ P + YLN H ALE++R  A  +  RGPR+M+ G   VGK+T+CR+L NYA R  R+   ++ +VG   + +PG++GAL + +P +V EG+ I + PL+Y FG  +P  N+KL++   + LA++ N R E +      GC+IN  G  K          G +A+  A SAFEV+++++++   L N L++DLP +V  + +PKS G   R+ +  ++ R   I  YF+G RG     PH   +   + KIYK+       + LP   + ED   KLV V   R + + +L+VS A   +E +   +  GF+VV SV  ++   TVLSP     P N L++ DI+++D+
Sbjct:   13 TKFELERETELRFEVEASQSVQLELLAGMAEIFGTELTRNKKFTFDAGAKVAVFTWHGCSLQLSGRTEVAYV-----SKDTPMLLYLNTHTALEQMRRQAEKEEERGPRVMVVGPTDVGKSTVCRLLLNYAVRLGRRPTYVELDVGQGSVSIPGTMGALYIERPADVEEGFSI-QAPLVYHFGSTTPGTNIKLYNKITSRLADVFNQRCEVNRRASVSGCVINTCGWVKG--------YGYQALVHAASAFEVDVVVVLDQERLYNELKRDLPHFVRTVLLPKSGGVVERSKDFRRECRDERIREYFYGFRGC--FYPHAFNVKFSDVKIYKVGAPTIPDSCLPLGMSQEDNQLKLVPVTPGRDMVHHLLSVSTAEGTEENLSETSVAGFIVVTSVDVEHQVFTVLSPAPRPLPKNFLLIMDIRFMDL 424
[Close]
BLAST of Protein CLP1 homolog vs. Ensembl Mouse
Match: Clp1 (CLP1, cleavage and polyadenylation factor I subunit [Source:MGI Symbol;Acc:MGI:2138968])

HSP 1 Score: 241.121 bits (614), Expect = 1.408e-74
Identity = 144/428 (33.64%), Postives = 237/428 (55.37%), Query Frame = 1 
Query:   67 TEVKLKAQQMMRFECTSVTIIKL--VEGSAELFGTELSTKGALNLQQGFLGTILTFNGCTLKYTSNTIIQFTVGFNEDQELPNV-YLNFHAALEKIRNNANNDI-RGPRLMICGNESVGKTTLCRILSNYAARKYRKVILIDANVGMNDICLPGSIGALIVTKPYEVVEGWDIFEDPLIYSFGHLSPVENLKLFSLQLNNLAELVNIRSENDPEVFAGGCIINMSGVSKSDDSGESQKKGIEAIRAAISAFEVNLLIIIEDGFLENLLRKDLPDYVSVIRIPKSSGAHSRTPEQWQKERTSNIASYFHG-RGLHKLQPHKLTLLAENYKIYKIDLKKSTLALLPNDDTMEDEWCKLVEVPFSRSLSNRVLAVSEALDVDE-IPGAACYGFVVVLSVAPDNSSITVLSPGNDEPPNNILVMTDIQYVDM 1332
            T+ +L+ +  +RFE  +   ++L  + G AE+FGTEL+         G    + T++GC+L+ +  T + +       ++ P + YLN H ALE++R  A  +  RGPR+M+ G   VGK+T+CR+L NYA R  R+   ++ +VG   + +PG++GAL + +P +V EG+ I + PL+Y FG  +P  N+KL++   + LA++ N R E +      GC+IN  G  K          G +A+  A SAFEV+++++++   L N L++DLP +V  + +PKS G   R+ +  ++ R   I  YF+G RG     PH   +   + KIYK+       + LP   + ED   KLV V   R + + +L+VS A   +E +   +  GF+VV SV  ++   TVLSP     P N L++ DI+++D+
Sbjct:   13 TKFELERETELRFEVEASQSVQLELLAGMAEIFGTELTRNKKFTFDAGAKVAVFTWHGCSLQLSGRTEVAYV-----SKDTPMLLYLNTHTALEQMRRQAEKEEERGPRVMVVGPTDVGKSTVCRLLLNYAVRLGRRPTYVELDVGQGSVSIPGTMGALYIERPADVEEGFSI-QAPLVYHFGSTTPGTNIKLYNKITSRLADVFNQRCEVNRRASVSGCVINTCGWVKG--------YGYQALVHAASAFEVDVVVVLDQERLYNELKRDLPHFVRTVLLPKSGGVVERSKDFRRECRDERIREYFYGFRGC--FYPHAFNVKFSDVKIYKVGAPTIPDSCLPLGMSQEDNQLKLVPVTPGRDMVHHLLSVSTAEGTEENLSETSVAGFIVVTSVDVEHQVFTVLSPAPRPLPKNFLLIMDIRFMDL 424
[Close]
BLAST of Protein CLP1 homolog vs. UniProt/SwissProt
Match: sp|A2VE01|CLP1_BOVIN (Polyribonucleotide 5'-hydroxyl-kinase Clp1 OS=Bos taurus OX=9913 GN=CLP1 PE=2 SV=1)

HSP 1 Score: 241.891 bits (616), Expect = 5.303e-74
Identity = 144/428 (33.64%), Postives = 237/428 (55.37%), Query Frame = 1 
Query:   67 TEVKLKAQQMMRFECTSVTIIKL--VEGSAELFGTELSTKGALNLQQGFLGTILTFNGCTLKYTSNTIIQFTVGFNEDQELPNV-YLNFHAALEKIRNNANNDI-RGPRLMICGNESVGKTTLCRILSNYAARKYRKVILIDANVGMNDICLPGSIGALIVTKPYEVVEGWDIFEDPLIYSFGHLSPVENLKLFSLQLNNLAELVNIRSENDPEVFAGGCIINMSGVSKSDDSGESQKKGIEAIRAAISAFEVNLLIIIEDGFLENLLRKDLPDYVSVIRIPKSSGAHSRTPEQWQKERTSNIASYFHG-RGLHKLQPHKLTLLAENYKIYKIDLKKSTLALLPNDDTMEDEWCKLVEVPFSRSLSNRVLAVSEALDVDE-IPGAACYGFVVVLSVAPDNSSITVLSPGNDEPPNNILVMTDIQYVDM 1332
            T+ +L+ +  +RFE  +   ++L  + G AE+FGTEL+         G    + T++GC+L+ +  T + +       ++ P + YLN H ALE++R  A  +  RGPR+M+ G   VGK+T+CR+L NYA R  R+   ++ +VG   + +PG++GAL + +P +V EG+ I + PL+Y FG  +P  N+KL++   + LA++ N R E +      GC+IN  G  K          G +A+  A SAFEV+++++++   L N L++DLP +V  + +PKS G   R+ +  ++ R   I  YF+G RG     PH   +   + KIYK+       + LP   + ED   KLV V   R + + +L+VS A   +E +   +  GF+VV SV  ++   TVLSP     P N L++ DI+++D+
Sbjct:   13 TKFELERETELRFEVEASQSVQLELLAGMAEIFGTELTRNKKFTFDAGAKVAVFTWHGCSLQLSGRTEVAYV-----SKDTPMLLYLNTHTALEQMRRQAEKEEERGPRVMVVGPTDVGKSTVCRLLLNYAVRLGRRPTYVELDVGQGSVSIPGTMGALYIERPADVEEGFSI-QAPLVYHFGSTTPGTNIKLYNKITSRLADVFNQRCEVNRRASVSGCVINTCGWVKGS--------GYQALVHAASAFEVDVVVVLDQERLYNELKRDLPHFVRTVLLPKSGGVVERSKDFRRECRDERIREYFYGFRGC--FYPHAFNVKFSDVKIYKVGAPTIPDSCLPLGMSQEDNQLKLVPVTPGRDMVHHLLSVSTAEGTEENLSETSVAGFIVVTSVDLEHQVFTVLSPAPRPLPKNFLLIMDIRFMDL 424
[Close]
BLAST of Protein CLP1 homolog vs. UniProt/SwissProt
Match: sp|Q5PQL4|CLP1_RAT (Polyribonucleotide 5'-hydroxyl-kinase Clp1 OS=Rattus norvegicus OX=10116 GN=Clp1 PE=2 SV=1)

HSP 1 Score: 241.121 bits (614), Expect = 9.848e-74
Identity = 144/428 (33.64%), Postives = 237/428 (55.37%), Query Frame = 1 
Query:   67 TEVKLKAQQMMRFECTSVTIIKL--VEGSAELFGTELSTKGALNLQQGFLGTILTFNGCTLKYTSNTIIQFTVGFNEDQELPNV-YLNFHAALEKIRNNANNDI-RGPRLMICGNESVGKTTLCRILSNYAARKYRKVILIDANVGMNDICLPGSIGALIVTKPYEVVEGWDIFEDPLIYSFGHLSPVENLKLFSLQLNNLAELVNIRSENDPEVFAGGCIINMSGVSKSDDSGESQKKGIEAIRAAISAFEVNLLIIIEDGFLENLLRKDLPDYVSVIRIPKSSGAHSRTPEQWQKERTSNIASYFHG-RGLHKLQPHKLTLLAENYKIYKIDLKKSTLALLPNDDTMEDEWCKLVEVPFSRSLSNRVLAVSEALDVDE-IPGAACYGFVVVLSVAPDNSSITVLSPGNDEPPNNILVMTDIQYVDM 1332
            T+ +L+ +  +RFE  +   ++L  + G AE+FGTEL+         G    + T++GC+L+ +  T + +       ++ P + YLN H ALE++R  A  +  RGPR+M+ G   VGK+T+CR+L NYA R  R+   ++ +VG   + +PG++GAL + +P +V EG+ I + PL+Y FG  +P  N+KL++   + LA++ N R E +      GC+IN  G  K          G +A+  A SAFEV+++++++   L N L++DLP +V  + +PKS G   R+ +  ++ R   I  YF+G RG     PH   +   + KIYK+       + LP   + ED   KLV V   R + + +L+VS A   +E +   +  GF+VV SV  ++   TVLSP     P N L++ DI+++D+
Sbjct:   13 TKFELERETELRFEVEASQSVQLELLAGMAEIFGTELTRNKKFTFDAGAKVAVFTWHGCSLQLSGRTEVAYV-----SKDTPMLLYLNTHTALEQMRRQAEKEEERGPRVMVVGPTDVGKSTVCRLLLNYAVRLGRRPTYVELDVGQGSVSIPGTMGALYIERPADVEEGFSI-QAPLVYHFGSTTPGTNIKLYNKITSRLADVFNQRCEVNRRASVSGCVINTCGWVKG--------YGYQALVHAASAFEVDVVVVLDQERLYNELKRDLPHFVRTVLLPKSGGVVERSKDFRRECRDERIREYFYGFRGC--FYPHAFNVKFSDVKIYKVGAPTIPDSCLPLGMSQEDNQLKLVPVTPGRDMVHHLLSVSTAEGTEENLSETSVAGFIVVTSVDVEHQVFTVLSPAPRPLPKNFLLIMDIRFMDL 424
[Close]
BLAST of Protein CLP1 homolog vs. UniProt/SwissProt
Match: sp|Q99LI9|CLP1_MOUSE (Polyribonucleotide 5'-hydroxyl-kinase Clp1 OS=Mus musculus OX=10090 GN=Clp1 PE=1 SV=1)

HSP 1 Score: 241.121 bits (614), Expect = 9.848e-74
Identity = 144/428 (33.64%), Postives = 237/428 (55.37%), Query Frame = 1 
Query:   67 TEVKLKAQQMMRFECTSVTIIKL--VEGSAELFGTELSTKGALNLQQGFLGTILTFNGCTLKYTSNTIIQFTVGFNEDQELPNV-YLNFHAALEKIRNNANNDI-RGPRLMICGNESVGKTTLCRILSNYAARKYRKVILIDANVGMNDICLPGSIGALIVTKPYEVVEGWDIFEDPLIYSFGHLSPVENLKLFSLQLNNLAELVNIRSENDPEVFAGGCIINMSGVSKSDDSGESQKKGIEAIRAAISAFEVNLLIIIEDGFLENLLRKDLPDYVSVIRIPKSSGAHSRTPEQWQKERTSNIASYFHG-RGLHKLQPHKLTLLAENYKIYKIDLKKSTLALLPNDDTMEDEWCKLVEVPFSRSLSNRVLAVSEALDVDE-IPGAACYGFVVVLSVAPDNSSITVLSPGNDEPPNNILVMTDIQYVDM 1332
            T+ +L+ +  +RFE  +   ++L  + G AE+FGTEL+         G    + T++GC+L+ +  T + +       ++ P + YLN H ALE++R  A  +  RGPR+M+ G   VGK+T+CR+L NYA R  R+   ++ +VG   + +PG++GAL + +P +V EG+ I + PL+Y FG  +P  N+KL++   + LA++ N R E +      GC+IN  G  K          G +A+  A SAFEV+++++++   L N L++DLP +V  + +PKS G   R+ +  ++ R   I  YF+G RG     PH   +   + KIYK+       + LP   + ED   KLV V   R + + +L+VS A   +E +   +  GF+VV SV  ++   TVLSP     P N L++ DI+++D+
Sbjct:   13 TKFELERETELRFEVEASQSVQLELLAGMAEIFGTELTRNKKFTFDAGAKVAVFTWHGCSLQLSGRTEVAYV-----SKDTPMLLYLNTHTALEQMRRQAEKEEERGPRVMVVGPTDVGKSTVCRLLLNYAVRLGRRPTYVELDVGQGSVSIPGTMGALYIERPADVEEGFSI-QAPLVYHFGSTTPGTNIKLYNKITSRLADVFNQRCEVNRRASVSGCVINTCGWVKG--------YGYQALVHAASAFEVDVVVVLDQERLYNELKRDLPHFVRTVLLPKSGGVVERSKDFRRECRDERIREYFYGFRGC--FYPHAFNVKFSDVKIYKVGAPTIPDSCLPLGMSQEDNQLKLVPVTPGRDMVHHLLSVSTAEGTEENLSETSVAGFIVVTSVDVEHQVFTVLSPAPRPLPKNFLLIMDIRFMDL 424
[Close]
BLAST of Protein CLP1 homolog vs. UniProt/SwissProt
Match: sp|Q4R7R3|CLP1_MACFA (Polyribonucleotide 5'-hydroxyl-kinase Clp1 OS=Macaca fascicularis OX=9541 GN=CLP1 PE=2 SV=1)

HSP 1 Score: 240.35 bits (612), Expect = 2.169e-73
Identity = 143/428 (33.41%), Postives = 237/428 (55.37%), Query Frame = 1 
Query:   67 TEVKLKAQQMMRFE--CTSVTIIKLVEGSAELFGTELSTKGALNLQQGFLGTILTFNGCTLKYTSNTIIQFTVGFNEDQELPNV-YLNFHAALEKIRNNANNDI-RGPRLMICGNESVGKTTLCRILSNYAARKYRKVILIDANVGMNDICLPGSIGALIVTKPYEVVEGWDIFEDPLIYSFGHLSPVENLKLFSLQLNNLAELVNIRSENDPEVFAGGCIINMSGVSKSDDSGESQKKGIEAIRAAISAFEVNLLIIIEDGFLENLLRKDLPDYVSVIRIPKSSGAHSRTPEQWQKERTSNIASYFHG-RGLHKLQPHKLTLLAENYKIYKIDLKKSTLALLPNDDTMEDEWCKLVEVPFSRSLSNRVLAVSEALDVDE-IPGAACYGFVVVLSVAPDNSSITVLSPGNDEPPNNILVMTDIQYVDM 1332
            T+ +L+ +  +RFE   +    ++L+ G AE+FGTEL+         G    + T++GC+++ +  T + +       ++ P + YLN H ALE++R  A  +  RGPR+M+ G   VGK+T+CR+L NYA R  R+   ++ +VG   + +PG++GAL + +P +V EG+ I + PL+Y FG  +P  N+KL++   + LA++ N R E +      GC+IN  G  K          G +A+  A SAFEV+++++++   L N L++DLP +V  + +PKS G   R+ +  ++ R   I  YF+G RG     PH   +   + KIYK+       + LP   + ED   KLV V   R + + +L+VS A   +E +   +  GF+VV SV  ++   TVLSP     P N L++ DI+++D+
Sbjct:   13 TKFELERETELRFEVEASQSVQLELLTGMAEIFGTELTRNKKFTFDAGAKVAVFTWHGCSVQLSGRTEVAYV-----SKDTPMLLYLNTHTALEQMRRQAEKEEERGPRVMVVGPTDVGKSTVCRLLLNYAVRLGRRPTYVELDVGQGSVSIPGTMGALYIERPADVEEGFSI-QAPLVYHFGSTTPGTNIKLYNKITSRLADVFNQRCEVNRRASVSGCVINTCGWVKGS--------GYQALVHAASAFEVDVVVVLDQERLYNELKRDLPHFVRTVLLPKSGGVVERSKDFRRECRDERIREYFYGFRGC--FYPHAFNVKFSDVKIYKVGAPTIPDSCLPLGMSQEDNQLKLVPVTPGRDMVHHLLSVSTAEGTEENLSETSVAGFIVVTSVDLEHQVFTVLSPAPRPLPKNFLLIMDIRFMDL 424
[Close]
BLAST of Protein CLP1 homolog vs. UniProt/SwissProt
Match: sp|Q92989|CLP1_HUMAN (Polyribonucleotide 5'-hydroxyl-kinase Clp1 OS=Homo sapiens OX=9606 GN=CLP1 PE=1 SV=1)

HSP 1 Score: 240.35 bits (612), Expect = 2.169e-73
Identity = 143/428 (33.41%), Postives = 237/428 (55.37%), Query Frame = 1 
Query:   67 TEVKLKAQQMMRFE--CTSVTIIKLVEGSAELFGTELSTKGALNLQQGFLGTILTFNGCTLKYTSNTIIQFTVGFNEDQELPNV-YLNFHAALEKIRNNANNDI-RGPRLMICGNESVGKTTLCRILSNYAARKYRKVILIDANVGMNDICLPGSIGALIVTKPYEVVEGWDIFEDPLIYSFGHLSPVENLKLFSLQLNNLAELVNIRSENDPEVFAGGCIINMSGVSKSDDSGESQKKGIEAIRAAISAFEVNLLIIIEDGFLENLLRKDLPDYVSVIRIPKSSGAHSRTPEQWQKERTSNIASYFHG-RGLHKLQPHKLTLLAENYKIYKIDLKKSTLALLPNDDTMEDEWCKLVEVPFSRSLSNRVLAVSEALDVDE-IPGAACYGFVVVLSVAPDNSSITVLSPGNDEPPNNILVMTDIQYVDM 1332
            T+ +L+ +  +RFE   +    ++L+ G AE+FGTEL+         G    + T++GC+++ +  T + +       ++ P + YLN H ALE++R  A  +  RGPR+M+ G   VGK+T+CR+L NYA R  R+   ++ +VG   + +PG++GAL + +P +V EG+ I + PL+Y FG  +P  N+KL++   + LA++ N R E +      GC+IN  G  K          G +A+  A SAFEV+++++++   L N L++DLP +V  + +PKS G   R+ +  ++ R   I  YF+G RG     PH   +   + KIYK+       + LP   + ED   KLV V   R + + +L+VS A   +E +   +  GF+VV SV  ++   TVLSP     P N L++ DI+++D+
Sbjct:   13 TKFELERETELRFEVEASQSVQLELLTGMAEIFGTELTRNKKFTFDAGAKVAVFTWHGCSVQLSGRTEVAYV-----SKDTPMLLYLNTHTALEQMRRQAEKEEERGPRVMVVGPTDVGKSTVCRLLLNYAVRLGRRPTYVELDVGQGSVSIPGTMGALYIERPADVEEGFSI-QAPLVYHFGSTTPGTNIKLYNKITSRLADVFNQRCEVNRRASVSGCVINTCGWVKGS--------GYQALVHAASAFEVDVVVVLDQERLYNELKRDLPHFVRTVLLPKSGGVVERSKDFRRECRDERIREYFYGFRGC--FYPHAFNVKFSDVKIYKVGAPTIPDSCLPLGMSQEDNQLKLVPVTPGRDMVHHLLSVSTAEGTEENLSETSVAGFIVVTSVDLEHQVFTVLSPAPRPLPKNFLLIMDIRFMDL 424
[Close]
BLAST of Protein CLP1 homolog vs. TrEMBL
Match: A0A430QGI2 (Polyribonucleotide 5'-hydroxyl-kinase OS=Schistosoma bovis OX=6184 GN=DC041_0005868 PE=3 SV=1)

HSP 1 Score: 438.343 bits (1126), Expect = 2.975e-148
Identity = 207/415 (49.88%), Postives = 289/415 (69.64%), Query Frame = 1 
Query:   94 MMRFECTSVTIIKLVEGSAELFGTELSTKGALNLQQGFLGTILTFNGCTLKYTSNTIIQFTVGFNEDQELPNVYLNFHAALEKIRNNA-NNDIRGPRLMICGNESVGKTTLCRILSNYAARKYRKVILIDANVGMNDICLPGSIGALIVTKPYEVVEGWDIFEDPLIYSFGHLSPVENLKLFSLQLNNLAELVNIRSENDPEVFAGGCIINMSGVSKSD-DSGESQKKGIEAIRAAISAFEVNLLIIIEDGFLENLLRKDLPDYVSVIRIPKSSGAHSRTPEQWQKERTSNIASYFHGRG-LHKLQPHKLTLLAENYKIYKIDLKKSTLALLPNDDTMEDEWCKLVEVPFSRSLSNRVLAVSEALDVDEIPGAACYGFVVVLSVAPDNSSITVLSPGNDEPPNNILVMTDIQYVD 1329
            M+RFE TS + + LV G+AE+FGTEL     L L  G  GT++TF+GC L      +  + +  +EDQE+ +VY+N HA LE  R  A     RGPR+++CG ESVGK+TLCR L++YAAR+  K IL+D NVG+N +C+P +I A+ VTKPY+++EGW + EDPL++ FGH  P  NL LF  Q+N LAEL+NIRSEND  +F  GCIINMSG  K D D G S++KGI+AIR   +AFEV+ L++IEDGFL + LR+DLP  V+++R+PKSSGA +R+P+QW ++R + + +Y HG   L +L PH++TL +  Y IYK+  +    ALLP+    E+ W   ++V  SR L NR+LAVS+A +  ++P A  YGF+VV+SV+ D S+ T+LSP +  PPNN+ ++T I YVD
Sbjct:    1 MLRFEVTSPSGLTLVSGAAEVFGTELVCGWELQLYPGQRGTVVTFHGCKLIVQDQGVAAYIIASSEDQEIVHVYMNIHANLEVSRQKAVKEQSRGPRVLVCGQESVGKSTLCRTLASYAARRKHKPILVDVNVGLNQVCIPTTIAAISVTKPYDLMEGWSLEEDPLVFCFGHTDPASNLNLFREQVNRLAELINIRSENDMSIFTSGCIINMSGFRKDDSDGGSSKEKGIQAIRTTAAAFEVDTLLVIEDGFLASFLREDLPPEVTIVRLPKSSGAITRSPDQWTRQRDARVCAYLHGENPLRRLHPHQITLKSSEYSIYKVGSEAIPDALLPHGAQEEETWRNPIQVSVSRDLKNRLLAVSQASEPYQVPEAPVYGFIVVVSVSEDKSAFTILSPSSHPPPNNLFLLTSICYVD 415
[Close]
BLAST of Protein CLP1 homolog vs. TrEMBL
Match: C1LK22 (Protein CLP1 homolog OS=Schistosoma japonicum OX=6182 GN=EWB00_004288 PE=2 SV=1)

HSP 1 Score: 434.491 bits (1116), Expect = 1.822e-146
Identity = 212/420 (50.48%), Postives = 292/420 (69.52%), Query Frame = 1 
Query:   79 LKAQQMMRFECTSVTIIKLVEGSAELFGTELSTKGALNLQQGFLGTILTFNGCTLKYTSNTIIQFTVGFNEDQELPNVYLNFHAALEKIRNNA-NNDIRGPRLMICGNESVGKTTLCRILSNYAARKYRKVILIDANVGMNDICLPGSIGALIVTKPYEVVEGWDIFEDPLIYSFGHLSPVENLKLFSLQLNNLAELVNIRSENDPEVFAGGCIINMSGVSKSD-DSGESQKKGIEAIRAAISAFEVNLLIIIEDGFLENLLRKDLPDYVSVIRIPKSSGAHSRTPEQWQKERTSNIASYFHGRG-LHKLQPHKLTLLAENYKIYKIDLKKSTLALLPNDDTMEDEWCKLVEVPFSRSLSNRVLAVSEALDVDEIPGAACYGFVVVLSVAPDNSSITVLSPGNDEPPNNILVMTDIQYVD 1329
            L+  QM+RFE TS + + LV G+AE+FGTEL     L L  G  GT++TF+GC L      +  + +  +EDQE+ +VY+N HA LE  R  A     RGPR+++CG ESVGK+TLCR L++YAAR+  K IL+D NVG+N IC+P +I A+ VTKPY+++EGW++ EDPL++ FGH  P  NL LF  Q+N LAEL+NIRSEND  +F  GCIINMSG  K D D G S++KGI+AIR   +AFEV+ L++IEDGFL + LR+DLP  V+++R+PKSSGA +R+P+QW ++R + + +Y HG   L +L PH+LTL A  Y IYK+  +    ALLP+    E+ W   ++V  SR L NR+LAVS+A +  ++P +  YGFVVV+SV+ D S+ T+LSP    PPNN+ ++T I YVD
Sbjct:   19 LEKYQMLRFEVTSSSCLTLVSGAAEVFGTELVCGWELQLYPGQRGTVVTFHGCKLIVQDQGVAAYIIASSEDQEIVHVYMNIHANLEVSRQKAVKEQSRGPRVLVCGQESVGKSTLCRTLASYAARRKHKPILVDVNVGLNQICIPTTIAAISVTKPYDLMEGWNLEEDPLVFCFGHTDPASNLNLFREQVNRLAELINIRSENDMSIFTSGCIINMSGFRKDDSDGGSSKEKGIQAIRTTAAAFEVDTLLVIEDGFLASFLREDLPPEVTIVRLPKSSGAITRSPDQWTRQRDARVCAYMHGENPLRRLHPHQLTLKASEYSIYKVGSEAIPDALLPHGAQEEETWRNAIQVSVSRELKNRLLAVSQASEPCQVPESPVYGFVVVVSVSEDKSAFTILSPSAHPPPNNLFLLTSICYVD 438
[Close]
BLAST of Protein CLP1 homolog vs. TrEMBL
Match: C1LK21 (Protein CLP1 homolog OS=Schistosoma japonicum OX=6182 PE=2 SV=1)

HSP 1 Score: 433.335 bits (1113), Expect = 4.450e-146
Identity = 211/420 (50.24%), Postives = 292/420 (69.52%), Query Frame = 1 
Query:   79 LKAQQMMRFECTSVTIIKLVEGSAELFGTELSTKGALNLQQGFLGTILTFNGCTLKYTSNTIIQFTVGFNEDQELPNVYLNFHAALEKIRNNA-NNDIRGPRLMICGNESVGKTTLCRILSNYAARKYRKVILIDANVGMNDICLPGSIGALIVTKPYEVVEGWDIFEDPLIYSFGHLSPVENLKLFSLQLNNLAELVNIRSENDPEVFAGGCIINMSGVSKSD-DSGESQKKGIEAIRAAISAFEVNLLIIIEDGFLENLLRKDLPDYVSVIRIPKSSGAHSRTPEQWQKERTSNIASYFHGRG-LHKLQPHKLTLLAENYKIYKIDLKKSTLALLPNDDTMEDEWCKLVEVPFSRSLSNRVLAVSEALDVDEIPGAACYGFVVVLSVAPDNSSITVLSPGNDEPPNNILVMTDIQYVD 1329
            L+  QM+RFE TS + + LV G+AE+FGTEL     L L  G  GT++TF+GC L      +  + +  +EDQE+ +VY+N HA LE  R  A     RGPR+++CG ESVGK+TLCR L++YAAR+  K IL+D NVG+N IC+P +I A+ VTKPY+++EGW++ EDPL++ FGH  P  NL LF  Q+N LAEL+NIRSEND  +F  GCIINMSG  K D D G S++KGI+AIR   +AFEV+ L++IEDGFL + LR+DLP  V+++R+PKSSGA +R+P+QW ++R + + +Y HG   L +L PH++TL A  Y IYK+  +    ALLP+    E+ W   ++V  SR L NR+LAVS+A +  ++P +  YGFVVV+SV+ D S+ T+LSP    PPNN+ ++T I YVD
Sbjct:   19 LEKYQMLRFEVTSSSCLTLVSGAAEVFGTELVCGWELQLYPGQRGTVVTFHGCKLIVQDQGVAAYIIASSEDQEIVHVYMNIHANLEVSRQKAVKEQSRGPRVLVCGQESVGKSTLCRTLASYAARRKHKPILVDVNVGLNQICIPTTIAAISVTKPYDLMEGWNLEEDPLVFCFGHTDPASNLNLFREQVNRLAELINIRSENDMSIFTSGCIINMSGFRKDDSDGGSSKEKGIQAIRTTAAAFEVDTLLVIEDGFLASFLREDLPPEVTIVRLPKSSGAITRSPDQWTRQRDARVCAYMHGENPLRRLHPHQITLKASEYSIYKVGSEAIPDALLPHGAQEEETWRNAIQVSVSRELKNRLLAVSQASEPCQVPESPVYGFVVVVSVSEDKSAFTILSPSAHPPPNNLFLLTSICYVD 438
[Close]
BLAST of Protein CLP1 homolog vs. TrEMBL
Match: A0A504YVP7 (Protein CLP1 homolog OS=Fasciola gigantica OX=46835 GN=FGIG_01575 PE=3 SV=1)

HSP 1 Score: 426.402 bits (1095), Expect = 3.063e-143
Identity = 205/421 (48.69%), Postives = 292/421 (69.36%), Query Frame = 1 
Query:   79 LKAQQMMRFECTSVTIIKLVEGSAELFGTELSTKGALNLQQGFLGTILTFNGCTLKYTSNTIIQFTVGFNEDQELPNVYLNFHAALEKIRNNANNDI-RGPRLMICGNESVGKTTLCRILSNYAARKYRKVILIDANVGMNDICLPGSIGALIVTKPYEVVEGWDIFEDPLIYSFGHLSPVENLKLFSLQLNNLAELVNIRSENDPEVFAGGCIINMSGVSKSD-DSGESQKKGIEAIRAAISAFEVNLLIIIEDGFLENLLRKDLPDYVSVIRIPKSSGAHSRTPEQWQKERTSNIASYFHGRG-LHKLQPHKLTLLAENYKIYKIDLKKSTLALLPNDDTMEDE-WCKLVEVPFSRSLSNRVLAVSEALDVDEIPGAACYGFVVVLSVAPDNSSITVLSPGNDEPPNNILVMTDIQYVD 1329
            L+  QM+R+E ++ + I L+ G+AE+FGTEL     L++  G  GT+ TF GC +      I  + +  +EDQ++ +VY+N HA+LE +R  A  D  RGPR+++CG+ESVGK+TLCR L++YAAR+  K IL+D NVG+N +CLP +I A+ +TKPY+++EGW + EDPL++ FGH+ P  NL LF  Q+N LAE VNIRSEND ++F  GCIINM G  K D D G S++KGI+AIRA  +AFEV+ +++IEDGFL   LR+DLP  V V R+PKSSG  +R+ +QW ++R + +++Y HG     +L PH++TL +  Y IYK+  +    ALLP+    ++E W   V+VP  R L NR+LA+S+A +   +P A  YGF+VV++V+ D SS TVLSP   EPPNN+L++T I YVD
Sbjct:   19 LEKYQMLRYEVSTPSSIILISGTAEIFGTELVAGAELHVSAGQRGTVTTFQGCKVVVHGYGIAAYLLSSSEDQDILHVYMNLHASLEAMRKAAIEDQGRGPRVLVCGHESVGKSTLCRTLASYAARRRHKPILVDVNVGLNQVCLPTTIAAVAITKPYDLMEGWGLEEDPLVFCFGHVDPDSNLNLFREQVNRLAEQVNIRSENDTKLFTSGCIINMGGFRKDDIDGGASKEKGIQAIRATAAAFEVDAVLVIEDGFLTTFLREDLPAEVVVARLPKSSGVVTRSADQWTRQRDARVSAYLHGENPFRRLHPHQITLKSNEYSIYKVGSEAIPDALLPHGAHEDEETWRHPVQVPIGRDLKNRLLAISQATEPQRVPEAPVYGFIVVVNVSDDKSSFTVLSPCPYEPPNNLLLLTTICYVD 439
[Close]
BLAST of Protein CLP1 homolog vs. TrEMBL
Match: A0A4S2MGB4 (Protein CLP1 homolog OS=Opisthorchis felineus OX=147828 GN=CRM22_000157 PE=3 SV=1)

HSP 1 Score: 424.861 bits (1091), Expect = 9.925e-143
Identity = 209/421 (49.64%), Postives = 290/421 (68.88%), Query Frame = 1 
Query:   79 LKAQQMMRFECTSVTIIKLVEGSAELFGTELSTKGALNLQQGFLGTILTFNGCTLKYTSNTIIQFTVGFNEDQELPNVYLNFHAALEKIRNNA-NNDIRGPRLMICGNESVGKTTLCRILSNYAARKYRKVILIDANVGMNDICLPGSIGALIVTKPYEVVEGWDIFEDPLIYSFGHLSPVENLKLFSLQLNNLAELVNIRSENDPEVFAGGCIINMSGVSKSD-DSGESQKKGIEAIRAAISAFEVNLLIIIEDGFLENLLRKDLPDYVSVIRIPKSSGAHSRTPEQWQKERTSNIASYFHGRG-LHKLQPHKLTLLAENYKIYKIDLKKSTLALLPNDDTMEDE-WCKLVEVPFSRSLSNRVLAVSEALDVDEIPGAACYGFVVVLSVAPDNSSITVLSPGNDEPPNNILVMTDIQYVD 1329
            L+  QM+RFE +S + + LV G+AE++GTEL     L L  G  GT++TF+GC +      I  F +   EDQE+ +VY+N HA+LE +R  A     RGPR+++CG+ESVGK+TLCR L++YAAR+  K IL+D NVG+N +CLP +I A+ V+KPY+++EGW + EDPL++ FGH++P  NL LF  Q+N LAELVNIRSEND ++F  GCIINM+G  K D D G S++KGI+AIRA  +AFEV+ +++IEDGFLE  LR+DLP  V++ R+PKSSG  +R+ +QW ++R + + +Y HG     +L PH++TL    Y IYK+  +    ALLP+    ++E W   V VP  R L N +LAVS+A D   +P A  YGFVV+++VA D SS TVLSP    PPNN+ ++T I YVD
Sbjct:   19 LEKYQMLRFEVSSPSSLVLVSGTAEIYGTELVCSSELLLNAGVRGTVVTFHGCKIVVNGPDITTFLMNVAEDQEIAHVYMNIHASLEVLRQKAVKEQSRGPRVLVCGHESVGKSTLCRTLASYAARRKHKPILVDVNVGLNQVCLPTTIAAVAVSKPYDLMEGWGLEEDPLVFCFGHVNPASNLNLFREQVNRLAELVNIRSENDTKIFTSGCIINMNGFRKDDSDGGTSKEKGIQAIRATAAAFEVDTILVIEDGFLETFLREDLPPEVTIARLPKSSGVVTRSADQWTRQRDARVCAYLHGENPFRRLHPHQITLKTSEYSIYKVGSEAIPDALLPHGAKEDEETWRNPVLVPIGRDLKNHLLAVSQASDPQHVPDAPVYGFVVIVNVADDKSSFTVLSPCPYAPPNNLFLLTTICYVD 439
[Close]
BLAST of Protein CLP1 homolog vs. Ensembl Cavefish
Match: clp1 (cleavage and polyadenylation factor I subunit 1 [Source:NCBI gene;Acc:103032393])

HSP 1 Score: 231.491 bits (589), Expect = 7.678e-71
Identity = 142/435 (32.64%), Postives = 234/435 (53.79%), Query Frame = 1 
Query:   67 TEVKLKAQQMMRFECTSVTIIKL--VEGSAELFGTELSTKGALNLQQGFLGTILTFNGCTLKYTSNTIIQFTVGFNEDQELPNVYLNFHAALEKIRNNANND-IRGPRLMICGNESVGKTTLCRILSNYAARKYRKVILIDANVGMNDICLPGSIGALIVTKPYEVVEGWDIFEDPLIYSFGHLSPVENLKLFSLQLNNLAELVNIRSENDPEVFAGGCIINMSGVSKSDDSGESQKKGIEAIRAAISAFEVNLLIIIEDGFLENLLRKDLPDYVSVIRIPKSSGAHSRTPEQWQKERTSNIASYFHGRGLHKLQPHKLTLLAENYKIYKIDLKKSTLALLPNDDTMEDEWCKLVEVPFSRSLSNRVLAVSEALDVDEIPGAA----------CYGFVVVLSVAPDNSSITVLSPGNDEPPNNILVMTDIQYVDM 1332
            T   L+ +  +RFE  S   ++L  + G  E+FG+EL+         G    + T+ GC+L  +  T + +    ++D  +  +YLN HAALE++R  A  D  RGPR+M+ G   VGK+T+CR+L NYA R  R+  L++ +VG + + +PG++ AL + +P +V EG+ + + PL++ FG  +P  N+KL++   + LAE+ + R E +     GGCIIN  G  K          G +A+    SAF+V+++++++   L N L++DLP +V V+ +PKS G   R+ +  ++ R   I  YF+G       PH   +   + +IYKI       + LP   + +D   KLV V   R L++ VL+VS     DE+ G +            GF+VV +V      +TVLSP     P + L++ DI+++D+
Sbjct:   11 TRYDLEKETELRFEVESGERVQLELLTGMGEVFGSELNRNKRYTFGPGSKIAVFTWQGCSLSLSGKTEVAY---ISKDTPM-LLYLNTHAALEQMRRQAERDNERGPRVMVVGPTDVGKSTVCRVLLNYAVRLGRRPTLVELDVGQSSVSVPGTMSALCIERPADVEEGFSV-QAPLVFHFGSTTPGTNIKLYNKLTSCLAEVFSQRCEVNRRASVGGCIINTCGWVKG--------SGYQALVHCASAFQVDVVLVLDQERLYNELKRDLPHFVRVVLLPKSGGVVERSKDCRRETRDDKIREYFYGFRGTSFYPHAFDVRFSDVRIYKIGAPSIPDSCLPLGMSQDDTQLKLVPVSPGRDLTHHVLSVSCV--EDEVDGGSGQSRGILESPVCGFIVVTAVDTQAQVMTVLSPAPRPLPRHTLLIMDIRFIDL 430
[Close]
BLAST of Protein CLP1 homolog vs. Ensembl Cavefish
Match: clp1 (cleavage and polyadenylation factor I subunit 1 [Source:NCBI gene;Acc:103032393])

HSP 1 Score: 230.335 bits (586), Expect = 2.764e-70
Identity = 141/431 (32.71%), Postives = 233/431 (54.06%), Query Frame = 1 
Query:   79 LKAQQMMRFECTSVTIIKL--VEGSAELFGTELSTKGALNLQQGFLGTILTFNGCTLKYTSNTIIQFTVGFNEDQELPNVYLNFHAALEKIRNNANND-IRGPRLMICGNESVGKTTLCRILSNYAARKYRKVILIDANVGMNDICLPGSIGALIVTKPYEVVEGWDIFEDPLIYSFGHLSPVENLKLFSLQLNNLAELVNIRSENDPEVFAGGCIINMSGVSKSDDSGESQKKGIEAIRAAISAFEVNLLIIIEDGFLENLLRKDLPDYVSVIRIPKSSGAHSRTPEQWQKERTSNIASYFHGRGLHKLQPHKLTLLAENYKIYKIDLKKSTLALLPNDDTMEDEWCKLVEVPFSRSLSNRVLAVSEALDVDEIPGAA----------CYGFVVVLSVAPDNSSITVLSPGNDEPPNNILVMTDIQYVDM 1332
            L+ +  +RFE  S   ++L  + G  E+FG+EL+         G    + T+ GC+L  +  T + +    ++D  +  +YLN HAALE++R  A  D  RGPR+M+ G   VGK+T+CR+L NYA R  R+  L++ +VG + + +PG++ AL + +P +V EG+ + + PL++ FG  +P  N+KL++   + LAE+ + R E +     GGCIIN  G  K          G +A+    SAF+V+++++++   L N L++DLP +V V+ +PKS G   R+ +  ++ R   I  YF+G       PH   +   + +IYKI       + LP   + +D   KLV V   R L++ VL+VS     DE+ G +            GF+VV +V      +TVLSP     P + L++ DI+++D+
Sbjct:   29 LEKETELRFEVESGERVQLELLTGMGEVFGSELNRNKRYTFGPGSKIAVFTWQGCSLSLSGKTEVAY---ISKDTPM-LLYLNTHAALEQMRRQAERDNERGPRVMVVGPTDVGKSTVCRVLLNYAVRLGRRPTLVELDVGQSSVSVPGTMSALCIERPADVEEGFSV-QAPLVFHFGSTTPGTNIKLYNKLTSCLAEVFSQRCEVNRRASVGGCIINTCGWVKG--------SGYQALVHCASAFQVDVVLVLDQERLYNELKRDLPHFVRVVLLPKSGGVVERSKDCRRETRDDKIREYFYGFRGTSFYPHAFDVRFSDVRIYKIGAPSIPDSCLPLGMSQDDTQLKLVPVSPGRDLTHHVLSVSCV--EDEVDGGSGQSRGILESPVCGFIVVTAVDTQAQVMTVLSPAPRPLPRHTLLIMDIRFIDL 444
[Close]
BLAST of Protein CLP1 homolog vs. Ensembl Sea Lamprey
Match: clp1 (cleavage and polyadenylation factor I subunit 1 [Source:NCBI gene;Acc:565621])

HSP 1 Score: 207.223 bits (526), Expect = 2.014e-62
Identity = 133/438 (30.37%), Postives = 230/438 (52.51%), Query Frame = 1 
Query:   46 MTEATD---WTEVKLKAQQMMRFEC--TSVTIIKLVEGSAELFGTELSTKGALNLQQGFLGTILTFNGCTLKYTSNTIIQFTVGFNEDQELPNV-YLNFHAALEKIRNNA--NNDIRGPRLMICGNESVGKTTLCRILSNYAARKYRKVILIDANVGMNDICLPGSIGALIVTKPYEVVEGWDIFEDPLIYSFGHLSPVENLKLFSLQLNNLAELVNIRSENDPEVFAGGCIINMSGVSKSDDSGESQKKGIEAIRAAISAFEVNLLIIIEDGFLENLLRKDLPDYVSVIRIPKSSGAHSRTPEQWQKERTSNIASYFHGRGLHKLQPHKLTLLAENYKIYKIDLKKSTLALLPNDDTMEDEWCKLVEVPFSRSLSNRVLAVSEALDVDE-IPGAACYGFVVVLSVAPDNSSITVLSPGNDEPPNNILVMTDIQYVDM 1332
            M+E  D     +  L+ +  +RFE        ++L+ G  E+FGTEL+         G    + T++GC+++ T  T + +       +E P + YLN HAALE++R  A    + RGPR+M+ G   VGK+TLCR+L +YAAR  R+  L++ +VG   + +PG++  L + +P +  EG+++ + PL+Y FG  +P  N+KL++  ++ LA++ + R + +      GC+IN  G  K          G +A+  A +AFE+ ++       L   L++DL  +V  + +PKS G   R+    ++ R   +  YF+G   +   PH   +   + K+YK+       + LP   + E+   K+V +   R L + VL++S A    E +  A+  GF+VV +V  +    TVLSP     P +IL++ DI+++D+
Sbjct:    1 MSEEKDDRPMQKFDLEKEMELRFEVEPQQTATLELLSGMGEIFGTELTRNKRYVFDAGSKVAVFTWHGCSVQLTGLTEVAYVA-----KETPMLLYLNVHAALEQMRVQAERQEEERGPRVMVAGPGDVGKSTLCRLLCSYAARLGRRPTLVELDVGQGSVSIPGTLALLYIERPADTEEGFNL-QAPLVYHFGSTTPSSNVKLYNKVVSKLADVFDQRCKVNRRAAISGCVINTCGWVKG--------AGYQALIHAATAFELPIVDKYHRAKLYTELKRDLTHFVKTVLLPKSGGVVERSKNFRREGRDELVRRYFYG-FRNAYFPHAFDVKFSDVKLYKVGAPPIPDSCLPLGMSQEENQLKVVPITPGRDLVHHVLSLSMAESTQENLVEASVAGFLVVTAVDSERQVFTVLSPAPRPLPRSILLVMDIRFMDL 423
[Close]
BLAST of Protein CLP1 homolog vs. Ensembl Yeast
Match: CLP1 (Component of the cleavage and polyadenylation factor I (CF I); CF 1, composed of the CF 1A complex (Rna14p, Rna15p, Clp1p, Pcf11p) and Hrp1, is involved in cleavage and polyadenylation of mRNA 3' ends; involved in both the endonucleolyitc cleavage and polyadenylation steps of mRNA 3'-end maturation and in gene looping which affects reinitiation of transcription [Source:SGD;Acc:S000005776])

HSP 1 Score: 90.1225 bits (222), Expect = 5.270e-20
Identity = 96/450 (21.33%), Postives = 191/450 (42.44%), Query Frame = 1 
Query:   43 IMTEATDWTEVKLKAQQMMRFECTSVTIIKLVEGSAELFGTELSTKGALNLQQGFLGTILTFNGCTLKYTSNTIIQFTVGFNEDQELPNVYLNFHAALEKIRNNANNDIRGPRLMICGNESVGKTTLCRILSNYAAR-KYRKVILIDANVGMNDICLPGSIGALIV---------TKPYEVVEGWDIFED--PLIYSFGHLSPVENLKLFSLQLNNLAELVNIRSENDPEVFAGGCIINMSGVSKSDDSGESQKKGIEAIRAAISAFEVNLLIII---EDGFLENLLRKDLPDYV--SVIRIPKSSGAHSRTPEQWQKERTSNIASYFHGRGLHKLQPHKLTLLAENYKIYK----IDLKKSTLALLPNDDTMEDEWCKLVEVPFSRSLSNRVLAVSEALDVDEIPGAACYGFVVVLSVAPDNSSITVLSPGNDEPPNNILVMTDIQYVD 1329
            ++ + +DW ++ LKA+  +        I+K+  G  E+FGTEL+       Q  +   I       L +    +   T+    +  +  +Y N H  LEKIR +   +  GPR++I G    GKT+L R L +YA +    + + I+ +       +PG I A  +         T    +  G  +  +  P++ +FG     EN  L+   ++ L ++V  R   DP+V   GCI++   +S+ D++       +  +   I    VN+++++    D   E + +   P+    ++  IPK  G  +      +  + ++I  YF+G     L P+ + +  E+  I+K     D +   + L P   T  +    ++ + F+   +++   +   +           GF ++  V      + VL P     P+  +++T  +Y++
Sbjct:   27 VIPKGSDW-QIDLKAEGKL--------IVKVNSGIVEIFGTELAVDDEYTFQ-NWKFPIYAVEETELLWKCPDLTTNTITVKPNHTMKYIY-NLHFMLEKIRMS---NFEGPRVVIVGGSQTGKTSLSRTLCSYALKFNAYQPLYINLDPQQPIFTVPGCISATPISDILDAQLPTWGQSLTSGATLLHNKQPMVKNFGLERINENKDLYLECISQLGQVVGQRLHLDPQVRRSGCIVDTPSISQLDEN-------LAELHHIIEKLNVNIMLVLCSETDPLWEKVKKTFGPELGNNNIFFIPKLDGVSAVDDVYKRSLQRTSIREYFYGSLDTALSPYAIGVDYEDLTIWKPSNVFDNEVGRVELFPVTITPSNLQHAIIAITFAERRADQATVIKSPI----------LGFALITEVNEKRRKLRVLLPVPGRLPSKAMILTSYRYLE 445
[Close]
BLAST of Protein CLP1 homolog vs. Ensembl Nematostella
Match: EDO49377 (Protein CLP1 homolog [Source:UniProtKB/Swiss-Prot;Acc:A7RG82])

HSP 1 Score: 212.616 bits (540), Expect = 3.751e-64
Identity = 140/435 (32.18%), Postives = 227/435 (52.18%), Query Frame = 1 
Query:   52 EATDWTEVKLKAQQMMRFECTS---VTIIKLVEGSAELFGTELSTKGALNLQQGFLGTILTFNGCTLKYTSNTIIQFTVGFNEDQELPNV-YLNFHAALEKIRNNANNDIR---GPRLMICGNESVGKTTLCRILSNYAARKYRKVILIDANVGMNDICLPGSIGALIVTKPYEVVEGWDIFEDPLIYSFGHLSPVENLKLFSLQLNNLAELVNIRSENDPEVFAGGCIINMSGVSKSDDSGESQKKGIEAIRAAISAFEVNLLIIIEDGFLENLLRKDLPDYVSVIRIPKSSGAHSRTPEQWQKERTSNIASYFHGRGLHKLQPHKLTLLAENYKIYKIDLKKSTLALLPNDDTMEDEWCKLVEVPFSRSLSNRVLAVSEALDVDE-IPGAACYGFVVVLSVAPDNSSITVLSPGNDEPPNNILVMTDIQYVDM 1332
            E   W   KL+    +R E        II L+ G+AE+FGTEL        + G    I T+ GC+++      + +     + +E P V YLN H ALE++R  A+       GPR+M+ G   VGK+T+C++L NYA R  R+ I +D +VG     +PGS+GAL++ +P ++ EG+ + + PL+Y FGH SP  N KL+++  + +A++V  R E + +  A GC+IN  G             G   I  A +AF+VN++++++   L N L+    D V ++ +PKS G   R+ E  +K R   + SYF+G+  + L PH   +   + K++KI       + LP          KLV V  ++ L + +LA+S A  ++E +      GF+VV  V  D   + VLSP     P   L++++I+++D 
Sbjct:   11 ERQQW---KLEKDTELRVEVAEGDREAIIVLLSGNAEVFGTELVKNKKFTFRPGSKLAIFTWQGCSVEIQGPLEVAY-----KSKETPMVMYLNLHMALEQMRERADKHEAVELGPRVMVVGPTDVGKSTVCQLLLNYAVRMGRRPISVDLDVGQGTASVPGSMGALLLERPADIEEGFSL-QAPLVYLFGHTSPSPNEKLYNMLSSKIADIVFQRFERNKKACASGCVINTCGWVTG--------MGYRIIVHAATAFKVNVIVVLDQERLYNDLKNQFGDKVQIVHLPKSGGVVVRSRETRRKVRDERLRSYFYGQQAN-LYPHSFEVKFSDVKLFKIGAPLVPDSCLPLGMDQGQNETKLVPVVPTKDLKHCLLAISAAESLEEDLVQTNVIGFLVVNEVDLDREVMVVLSPAPRPLPRKFLLLSEIKFMDF 427
[Close]
BLAST of Protein CLP1 homolog vs. Ensembl Medaka
Match: CLP1 (cleavage and polyadenylation factor I subunit 1 [Source:NCBI gene;Acc:101158455])

HSP 1 Score: 221.476 bits (563), Expect = 5.855e-67
Identity = 143/437 (32.72%), Postives = 230/437 (52.63%), Query Frame = 1 
Query:   61 DWTEVKLKAQQMMRFECTSVTI-----IKLVEGSAELFGTELSTKGALNLQQGFLGTILTFNGCTLKYTSNTIIQFTVGFNEDQELPNV-YLNFHAALEKIRNNANND-IRGPRLMICGNESVGKTTLCRILSNYAARKYRKVILIDANVGMNDICLPGSIGALIVTKPYEVVEGWDIFEDPLIYSFGHLSPVENLKLFSLQLNNLAELVNIRSENDPEVFAGGCIINMSGVSKSDDSGESQKKGIEAIRAAISAFEVNLLIIIEDGFLENLLRKDLPDYVSVIRIPKSSGAHSRTPEQWQKERTSNIASYFHG-RGLHKLQPHKLTLLAENYKIYKIDLKKSTLALLPNDDTMEDEWCKLVEVPFSRSLSNRVLAVSEALDVDE-----IPGAACYGFVVVLSVAPDNSSITVLSPGNDEPPNNILVMTDIQYVDM 1332
            D T   L+ +  +RFE  +        ++L+ G AE+FG+EL+         G    + T+ GC++       + +       ++ P + YLN HAALE++R  A  +  RGPR+M+ G   VGK+T+CR+L NYA R  R+  L++ +VG + + +PG++ AL + +P +V EG+ + + PL+Y FG  +P  N+KL++   + LAE+ + R E + +   GGCIIN  G  K          G +A+    S F+V+++++++   L N L++DLP +V V+ +PKS G   R+ E  +  R   I  YF+G RG+    P    +   + +IYKI       + LP   + +D   KLV V   R L+  VL+VS   D DE     I      GF+VV  V      + VLSP     P + L++ DI+++DM
Sbjct:   19 DCTRFDLEKETELRFEVEAGEAAEQVELELLSGLAEVFGSELNRNKKYVFGPGSKIAVFTWQGCSVNLHGKPEVAYV-----SKDTPMLLYLNTHAALEQMRKQAERENERGPRVMVVGPTDVGKSTVCRMLLNYAVRVGRRPTLVELDVGQSGVSVPGTVSALCIERPADVEEGFSV-QAPLVYHFGSTTPGTNIKLYNKLTSCLAEMFSQRCEVNRKASVGGCIINTCGWVKGS--------GYQALVHCASTFQVDVVLVLDHERLYNELKRDLPHFVRVVLLPKSGGVVERSKECRRDTRDEKIREYFYGFRGV-SYYPFSYEVRFSDVRIYKIGAPSIPDSCLPLGMSQDDTQLKLVPVTPGRDLTYHVLSVSSVDDGDEGARKSIVEIPVCGFIVVTFVDTQTQVMKVLSPAPRPLPRHTLLIMDIRFMDM 440
[Close]
BLAST of Protein CLP1 homolog vs. Ensembl Medaka
Match: CLP1 (cleavage and polyadenylation factor I subunit 1 [Source:NCBI gene;Acc:101158455])

HSP 1 Score: 204.142 bits (518), Expect = 1.316e-60
Identity = 139/437 (31.81%), Postives = 223/437 (51.03%), Query Frame = 1 
Query:   61 DWTEVKLKAQQMMRFECTSVTI-----IKLVEGSAELFGTELSTKGALNLQQGFLGTILTFNGCTLKYTSNTIIQFTVGFNEDQELPNV-YLNFHAALEKIRNNANND-IRGPRLMICGNESVGKTTLCRILSNYAARKYRKVILIDANVGMNDICLPGSIGALIVTKPYEVVEGWDIFEDPLIYSFGHLSPVENLKLFSLQLNNLAELVNIRSENDPEVFAGGCIINMSGVSKSDDSGESQKKGIEAIRAAISAFEVNLLIIIEDGFLENLLRKDLPDYVSVIRIPKSSGAHSRTPEQWQKERTSNIASYFHG-RGLHKLQPHKLTLLAENYKIYKIDLKKSTLALLPNDDTMEDEWCKLVEVPFSRSLSNRVLAVSEALDVDE-----IPGAACYGFVVVLSVAPDNSSITVLSPGNDEPPNNILVMTDIQYVDM 1332
            D T   L+ +  +RFE  +        ++L+ G AE+FG+EL+         G    + T+ GC++       + +       ++ P + YLN HAALE++R  A  +  RGPR+M+ G   VGK+T+CR+L NYA R  R+  L++ +VG + + +PG++ AL + +P +V EG+ + + PL+Y FG  +P  N+KL++   + LAE+ + R E + +   GGCIIN  G  K          G +A+    S F+V+++++++   L N L++DLP +V V+ +PKS G   R+ E  +  R   I  YF+G RG+             +Y  +  +           DDT      KLV V   R L+  VL+VS   D DE     I      GF+VV  V      + VLSP     P + L++ DI+++DM
Sbjct:   19 DCTRFDLEKETELRFEVEAGEAAEQVELELLSGLAEVFGSELNRNKKYVFGPGSKIAVFTWQGCSVNLHGKPEVAYV-----SKDTPMLLYLNTHAALEQMRKQAERENERGPRVMVVGPTDVGKSTVCRMLLNYAVRVGRRPTLVELDVGQSGVSVPGTVSALCIERPADVEEGFSV-QAPLVYHFGSTTPGTNIKLYNKLTSCLAEMFSQRCEVNRKASVGGCIINTCGWVKGS--------GYQALVHCASTFQVDVVLVLDHERLYNELKRDLPHFVRVVLLPKSGGVVERSKECRRDTRDEKIREYFYGFRGV-------------SYYPFSYE-----------DDTQ----LKLVPVTPGRDLTYHVLSVSSVDDGDEGARKSIVEIPVCGFIVVTFVDTQTQVMKVLSPAPRPLPRHTLLIMDIRFMDM 413
[Close]
BLAST of Protein CLP1 homolog vs. Planmine SMEST
Match: SMESG000047440.1 (SMESG000047440.1)

HSP 1 Score: 878.626 bits (2269), Expect = 0.000e+0
Identity = 429/435 (98.62%), Postives = 429/435 (98.62%), Query Frame = 1 
Query:   46 MTEATDWTEVKLKAQQMMRFECTSVTIIKLVEGSAELFGTELSTKGALNLQQGFLGTILTFNGCTLKYTSNTIIQFTVGFNEDQELPNVYLNFHAALEKIRNNANNDIRGPRLMICGNESVGKTTLCRILSNYAARKYRKVILIDANVGMNDICLPGSIGALIVTKPYEVVEGWDIFEDPLIYSFGHLSPVENLKLFSLQLNNLAELVNIRSENDPEVFAGGCIINMSGVSKSDDSGESQKKGIEAIRAAISAFEVNLLIIIEDGFLENLLRKDLPDYVSVIRIPKSSGAHSRTPEQWQKERTSNIASYFHGRGLHKLQPHKLTLLAEN------YKIYKIDLKKSTLALLPNDDTMEDEWCKLVEVPFSRSLSNRVLAVSEALDVDEIPGAACYGFVVVLSVAPDNSSITVLSPGNDEPPNNILVMTDIQYVDM 1332
            MTEATDWTEVKLKAQQMMRFECTSVTIIKLVEGSAELFGTELSTKGALNLQQGFLGTILTFNGCTLKYTSNTIIQFTVGFNEDQELPNVYLNFHAALEKIRNNANNDIRGPRLMICGNESVGKTTLCRILSNYAARKYRKVILIDANVGMNDICLPGSIGALIVTKPYEVVEGWDIFEDPLIYSFGHLSPVENLKLFSLQLNNLAELVNIRSENDPEVFAGGCIINMSGVSKSDDSGESQKKGIEAIRAAISAFEVNLLIIIEDGFLENLLRKDLPDYVSVIRIPKSSGAHSRTPEQWQKERTSNIASYFHGRGLHKLQPHKLTLLAEN      YKIYKIDLKKSTLALLPNDDTMEDEWCKLVEVPFSRSLSNRVLAVSEALDVDEIPGAACYGFVVVLSVAPDNSSITVLSPGNDEPPNNILVMTDIQYVDM
Sbjct:    1 MTEATDWTEVKLKAQQMMRFECTSVTIIKLVEGSAELFGTELSTKGALNLQQGFLGTILTFNGCTLKYTSNTIIQFTVGFNEDQELPNVYLNFHAALEKIRNNANNDIRGPRLMICGNESVGKTTLCRILSNYAARKYRKVILIDANVGMNDICLPGSIGALIVTKPYEVVEGWDIFEDPLIYSFGHLSPVENLKLFSLQLNNLAELVNIRSENDPEVFAGGCIINMSGVSKSDDSGESQKKGIEAIRAAISAFEVNLLIIIEDGFLENLLRKDLPDYVSVIRIPKSSGAHSRTPEQWQKERTSNIASYFHGRGLHKLQPHKLTLLAENVVAFFQYKIYKIDLKKSTLALLPNDDTMEDEWCKLVEVPFSRSLSNRVLAVSEALDVDEIPGAACYGFVVVLSVAPDNSSITVLSPGNDEPPNNILVMTDIQYVDM 435
[Close]
BLAST of Protein CLP1 homolog vs. Planmine SMEST
Match: SMESG000028257.1 (SMESG000028257.1)

HSP 1 Score: 878.626 bits (2269), Expect = 0.000e+0
Identity = 429/435 (98.62%), Postives = 429/435 (98.62%), Query Frame = 1 
Query:   46 MTEATDWTEVKLKAQQMMRFECTSVTIIKLVEGSAELFGTELSTKGALNLQQGFLGTILTFNGCTLKYTSNTIIQFTVGFNEDQELPNVYLNFHAALEKIRNNANNDIRGPRLMICGNESVGKTTLCRILSNYAARKYRKVILIDANVGMNDICLPGSIGALIVTKPYEVVEGWDIFEDPLIYSFGHLSPVENLKLFSLQLNNLAELVNIRSENDPEVFAGGCIINMSGVSKSDDSGESQKKGIEAIRAAISAFEVNLLIIIEDGFLENLLRKDLPDYVSVIRIPKSSGAHSRTPEQWQKERTSNIASYFHGRGLHKLQPHKLTLLAEN------YKIYKIDLKKSTLALLPNDDTMEDEWCKLVEVPFSRSLSNRVLAVSEALDVDEIPGAACYGFVVVLSVAPDNSSITVLSPGNDEPPNNILVMTDIQYVDM 1332
            MTEATDWTEVKLKAQQMMRFECTSVTIIKLVEGSAELFGTELSTKGALNLQQGFLGTILTFNGCTLKYTSNTIIQFTVGFNEDQELPNVYLNFHAALEKIRNNANNDIRGPRLMICGNESVGKTTLCRILSNYAARKYRKVILIDANVGMNDICLPGSIGALIVTKPYEVVEGWDIFEDPLIYSFGHLSPVENLKLFSLQLNNLAELVNIRSENDPEVFAGGCIINMSGVSKSDDSGESQKKGIEAIRAAISAFEVNLLIIIEDGFLENLLRKDLPDYVSVIRIPKSSGAHSRTPEQWQKERTSNIASYFHGRGLHKLQPHKLTLLAEN      YKIYKIDLKKSTLALLPNDDTMEDEWCKLVEVPFSRSLSNRVLAVSEALDVDEIPGAACYGFVVVLSVAPDNSSITVLSPGNDEPPNNILVMTDIQYVDM
Sbjct:    1 MTEATDWTEVKLKAQQMMRFECTSVTIIKLVEGSAELFGTELSTKGALNLQQGFLGTILTFNGCTLKYTSNTIIQFTVGFNEDQELPNVYLNFHAALEKIRNNANNDIRGPRLMICGNESVGKTTLCRILSNYAARKYRKVILIDANVGMNDICLPGSIGALIVTKPYEVVEGWDIFEDPLIYSFGHLSPVENLKLFSLQLNNLAELVNIRSENDPEVFAGGCIINMSGVSKSDDSGESQKKGIEAIRAAISAFEVNLLIIIEDGFLENLLRKDLPDYVSVIRIPKSSGAHSRTPEQWQKERTSNIASYFHGRGLHKLQPHKLTLLAENVVAFFQYKIYKIDLKKSTLALLPNDDTMEDEWCKLVEVPFSRSLSNRVLAVSEALDVDEIPGAACYGFVVVLSVAPDNSSITVLSPGNDEPPNNILVMTDIQYVDM 435
[Close]
BLAST of Protein CLP1 homolog vs. Planmine SMEST
Match: SMESG000047440.1 (SMESG000047440.1)

HSP 1 Score: 873.233 bits (2255), Expect = 0.000e+0
Identity = 426/432 (98.61%), Postives = 426/432 (98.61%), Query Frame = 1 
Query:   46 MTEATDWTEVKLKAQQMMRFECTSVTIIKLVEGSAELFGTELSTKGALNLQQGFLGTILTFNGCTLKYTSNTIIQFTVGFNEDQELPNVYLNFHAALEKIRNNANNDIRGPRLMICGNESVGKTTLCRILSNYAARKYRKVILIDANVGMNDICLPGSIGALIVTKPYEVVEGWDIFEDPLIYSFGHLSPVENLKLFSLQLNNLAELVNIRSENDPEVFAGGCIINMSGVSKSDDSGESQKKGIEAIRAAISAFEVNLLIIIEDGFLENLLRKDLPDYVSVIRIPKSSGAHSRTPEQWQKERTSNIASYFHGRGLHKLQPHKLTLLAEN------YKIYKIDLKKSTLALLPNDDTMEDEWCKLVEVPFSRSLSNRVLAVSEALDVDEIPGAACYGFVVVLSVAPDNSSITVLSPGNDEPPNNILVMTDIQY 1323
            MTEATDWTEVKLKAQQMMRFECTSVTIIKLVEGSAELFGTELSTKGALNLQQGFLGTILTFNGCTLKYTSNTIIQFTVGFNEDQELPNVYLNFHAALEKIRNNANNDIRGPRLMICGNESVGKTTLCRILSNYAARKYRKVILIDANVGMNDICLPGSIGALIVTKPYEVVEGWDIFEDPLIYSFGHLSPVENLKLFSLQLNNLAELVNIRSENDPEVFAGGCIINMSGVSKSDDSGESQKKGIEAIRAAISAFEVNLLIIIEDGFLENLLRKDLPDYVSVIRIPKSSGAHSRTPEQWQKERTSNIASYFHGRGLHKLQPHKLTLLAEN      YKIYKIDLKKSTLALLPNDDTMEDEWCKLVEVPFSRSLSNRVLAVSEALDVDEIPGAACYGFVVVLSVAPDNSSITVLSPGNDEPPNNILVMTDIQY
Sbjct:    1 MTEATDWTEVKLKAQQMMRFECTSVTIIKLVEGSAELFGTELSTKGALNLQQGFLGTILTFNGCTLKYTSNTIIQFTVGFNEDQELPNVYLNFHAALEKIRNNANNDIRGPRLMICGNESVGKTTLCRILSNYAARKYRKVILIDANVGMNDICLPGSIGALIVTKPYEVVEGWDIFEDPLIYSFGHLSPVENLKLFSLQLNNLAELVNIRSENDPEVFAGGCIINMSGVSKSDDSGESQKKGIEAIRAAISAFEVNLLIIIEDGFLENLLRKDLPDYVSVIRIPKSSGAHSRTPEQWQKERTSNIASYFHGRGLHKLQPHKLTLLAENVVAFFQYKIYKIDLKKSTLALLPNDDTMEDEWCKLVEVPFSRSLSNRVLAVSEALDVDEIPGAACYGFVVVLSVAPDNSSITVLSPGNDEPPNNILVMTDIQY 432
[Close]
BLAST of Protein CLP1 homolog vs. Planmine SMEST
Match: SMESG000066272.1 (SMESG000066272.1)

HSP 1 Score: 272.322 bits (695), Expect = 5.484e-87
Identity = 146/425 (34.35%), Postives = 233/425 (54.82%), Query Frame = 1 
Query:   52 EATDWTE-VKLKAQQMMRFECTSVTIIKLVEGSAELFGTELSTKGALNLQQGFLGTILTFNGCTLKYTSNTIIQFTVGFNEDQELPNVYLNFHAALEKIRNNANNDIRGPRLMICGNESVGKTTLCRILSNYAARKYRKVILIDANVGMNDICLPGSIGALIVTKPYEVVEGWDIFEDPLIYSFGHLSPVENLKLFSLQLNNLAELVNIRSENDPEVFAGGCIINMSGVSKSDDSGESQKKGIEAIRAAISAFEVNLLIIIEDGFLENLLRKDLPDYVSVIRIPKSSGAHSRTPEQWQKERTSNIASYFHGRGLHKLQPHKLTLLAENYKIYKIDLK-KSTLALLPNDDTMEDEWCKLVEVPFSRSLSNRVLAVSEALDVDEIPGAACYGFVVVLSVAPDNSSITVLSPGNDEPPNNILVMTDIQ 1320
            E   W+E + LK Q+ +RF+C+  T + + +G +E++G+E     ++N    F G+++TF GCT +Y +     + V F+ED    NVYLN H+ LE  RN  +N  RGPR+MICG  + GK  L + L NY  R + +++ +D NV  N IC+PGS+ ALIVT+ Y+V +GW I + PLI +FGHLSP+++L+L+ LQL  L+  VN +  N+ ++   G I+N S          ++ + +E +   I  F+++ +IIIED FL+  +++ L   +SV+ IP+SS +  RT +           SYF G+G+++L     TL  ++  IYK D   K     L N   M            SR   N VLAVS+   V+++     +G++++  V      I +L+P     P    + TD +
Sbjct:    2 ENDPWSEEINLKPQETLRFKCSENTSLIMTQGLSEIYGSEFPRDNSVNFPTNFEGSLITFVGCTYRYRAANFPYYIVKFDEDSFCYNVYLNIHSGLETKRNVCSN--RGPRVMICGGRNAGKKNLSQTLVNYRIRNFGEIVFVDTNVSDNSICIPGSLAALIVTQAYDVTDGWHINDQPLIINFGHLSPMDDLELYKLQLKTLSGFVNDKMTNNAKLNRSGIILNSSAFEDEKYPEFTRDRRVELLLENIYLFQIDHVIIIEDLFLQKQIKEKLNSKISVVSIPRSSESFKRTEKTLFDYYQMKTTSYFEGQGIYRLHFKTFTLFTQDVSIYKFDEDIKEIDVKLKNPKLMR----------MSRYFRNSVLAVSQTCKVEDLYKTPIFGYIMITEVKKYLDKIKILTPSGMPVPLKTFLYTDFK 414
[Close]
BLAST of Protein CLP1 homolog vs. Planmine SMEST
Match: SMESG000020165.1 (SMESG000020165.1)

HSP 1 Score: 208.764 bits (530), Expect = 4.971e-59
Identity = 138/403 (34.24%), Postives = 214/403 (53.10%), Query Frame = 1 
Query:   70 EVKLKAQQMMRFECTSVTIIKLVEGSAELFGTELSTKGALNLQQGFLGTILTFNGCTLKYTSNTIIQFTVGFNEDQELPNVYLNFHAALEKIRNNA-NNDIRGPRLMICGN--ESVGKTTLCRILSNYAARKYRKVILIDANVGMNDICLPGSIGALIVTKPYEVVEGWDIFEDPLIYSFGHLSPVENLKLFSLQLNNLAELVNIRSENDPEVFAGGCIINMSGVSKSDDSGESQKKGIEAIRAAISAFEVNLLIIIEDGFLENLLRKDLPDYVSVIRIPKSSGAHSRTPEQWQKERTSNIASYFHGRGLHKLQPHKLTLLAENYKIYKIDLKKSTLALLPNDDTMEDEWCKLVEVPFSRSLSNRVLAVSEALDVDEIPGAACYGFVVVLSVAPDNSSITVLS 1269
            ++ L +++++RF C +   I+L +G+AE++GT L     + L++     IL+F GC++    N           D   PN+ LN H  LE  R  A  ND+RGPR++I G   E+   +TL R L+NY+ R  R V L++ +   ND  LP SI   ++   +++  GWD   DPL+++FG  SPV N +L+  QL+ LA  VNIR END  +  GGCIIN      S           E I  AI  FEVN+L++I D    N L   +P+YV +I IPK     +  P++ +  RT  I +YF+ +  HKL  H+L   A+  KIY       T +L  ++D+        + +PF   + N V A+S+AL  DEI  +    ++++  V+   S++TV++
Sbjct:  555 KIILNSEEIVRFFCLNNVRIRLYKGTAEIYGTALPFNHEIELRKNNHYEILSFTGCSIMVIGNINEVKVKSICFDLYKPNIILNIHYDLELKRIEALKNDVRGPRILIYGPGVEAFSMSTLTRTLANYSVRCGRTVALVNLDSIYNDTGLPNSISVNVIQVEFDLQRGWDFCNDPLVFNFGQCSPVANQRLYFEQLDALANYVNIRCENDNNLLIGGCIINGGSFHSS-----------EIILKAIQLFEVNVLLLISDSSTIN-LSSQVPEYVQIINIPKDLFDTNFCPKKIESIRTERIHAYFYEQ--HKLFKHELK--ADEVKIY------YTKSLNDSNDS------NFINIPFQEIILNSVCALSQALSFDEISTSPILCYLLITDVSECYSTLTVMA 929
The following BLAST results are available for this feature:
BLAST of Protein CLP1 homolog vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5
Match NameE-valueIdentityDescription
CLP14.517e-7433.41cleavage and polyadenylation factor I subunit 1 [S... [more]
CLP14.517e-7433.41cleavage and polyadenylation factor I subunit 1 [S... [more]
CLP15.467e-7433.41cleavage and polyadenylation factor I subunit 1 [S... [more]
CLP14.782e-2832.61cleavage and polyadenylation factor I subunit 1 [S... [more]
CLP12.611e-1532.80cleavage and polyadenylation factor I subunit 1 [S... [more]
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BLAST of Protein CLP1 homolog vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 1
Match NameE-valueIdentityDescription
clpf-15.979e-6030.39pep chromosome:WBcel235:III:3397743:3400644:1 gene... [more]
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BLAST of Protein CLP1 homolog vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 1
Match NameE-valueIdentityDescription
cbc2.140e-5631.41gene:FBgn0033842 transcript:FBtr0087701[more]
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BLAST of Protein CLP1 homolog vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 1
Match NameE-valueIdentityDescription
clp19.218e-7132.56cleavage and polyadenylation factor I subunit 1 [S... [more]
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BLAST of Protein CLP1 homolog vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 1
Match NameE-valueIdentityDescription
clp19.615e-7032.17cleavage and polyadenylation factor I subunit 1 [S... [more]
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BLAST of Protein CLP1 homolog vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 2
Match NameE-valueIdentityDescription
Clp11.408e-7433.64CLP1, cleavage and polyadenylation factor I subuni... [more]
Clp11.408e-7433.64CLP1, cleavage and polyadenylation factor I subuni... [more]
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BLAST of Protein CLP1 homolog vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|A2VE01|CLP1_BOVIN5.303e-7433.64Polyribonucleotide 5'-hydroxyl-kinase Clp1 OS=Bos ... [more]
sp|Q5PQL4|CLP1_RAT9.848e-7433.64Polyribonucleotide 5'-hydroxyl-kinase Clp1 OS=Ratt... [more]
sp|Q99LI9|CLP1_MOUSE9.848e-7433.64Polyribonucleotide 5'-hydroxyl-kinase Clp1 OS=Mus ... [more]
sp|Q4R7R3|CLP1_MACFA2.169e-7333.41Polyribonucleotide 5'-hydroxyl-kinase Clp1 OS=Maca... [more]
sp|Q92989|CLP1_HUMAN2.169e-7333.41Polyribonucleotide 5'-hydroxyl-kinase Clp1 OS=Homo... [more]
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BLAST of Protein CLP1 homolog vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
A0A430QGI22.975e-14849.88Polyribonucleotide 5'-hydroxyl-kinase OS=Schistoso... [more]
C1LK221.822e-14650.48Protein CLP1 homolog OS=Schistosoma japonicum OX=6... [more]
C1LK214.450e-14650.24Protein CLP1 homolog OS=Schistosoma japonicum OX=6... [more]
A0A504YVP73.063e-14348.69Protein CLP1 homolog OS=Fasciola gigantica OX=4683... [more]
A0A4S2MGB49.925e-14349.64Protein CLP1 homolog OS=Opisthorchis felineus OX=1... [more]
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BLAST of Protein CLP1 homolog vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 2
Match NameE-valueIdentityDescription
clp17.678e-7132.64cleavage and polyadenylation factor I subunit 1 [S... [more]
clp12.764e-7032.71cleavage and polyadenylation factor I subunit 1 [S... [more]
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BLAST of Protein CLP1 homolog vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 1
Match NameE-valueIdentityDescription
clp12.014e-6230.37cleavage and polyadenylation factor I subunit 1 [S... [more]
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BLAST of Protein CLP1 homolog vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 1
Match NameE-valueIdentityDescription
CLP15.270e-2021.33Component of the cleavage and polyadenylation fact... [more]
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BLAST of Protein CLP1 homolog vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 1
Match NameE-valueIdentityDescription
EDO493773.751e-6432.18Protein CLP1 homolog [Source:UniProtKB/Swiss-Prot... [more]
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BLAST of Protein CLP1 homolog vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 2
Match NameE-valueIdentityDescription
CLP15.855e-6732.72cleavage and polyadenylation factor I subunit 1 [S... [more]
CLP11.316e-6031.81cleavage and polyadenylation factor I subunit 1 [S... [more]
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BLAST of Protein CLP1 homolog vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5
Match NameE-valueIdentityDescription
SMESG000047440.10.000e+098.62SMESG000047440.1[more]
SMESG000028257.10.000e+098.62SMESG000028257.1[more]
SMESG000047440.10.000e+098.61SMESG000047440.1[more]
SMESG000066272.15.484e-8734.35SMESG000066272.1[more]
SMESG000020165.14.971e-5934.24SMESG000020165.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30013758 ID=SMED30013758|Name=Protein CLP1 homolog|organism=Schmidtea mediterranea sexual|type=transcript|length=1360bp
TTTCGATTTAGCGCATTTTAAAAATTTATTATCATTTATTAAATTATGAC
TGAGGCTACTGATTGGACTGAAGTTAAGTTAAAAGCTCAGCAAATGATGA
GATTTGAGTGTACATCTGTAACAATTATAAAGCTAGTTGAAGGATCTGCA
GAATTGTTTGGTACAGAATTATCAACTAAAGGTGCTCTTAATTTACAACA
AGGATTCCTTGGAACTATTTTGACATTTAATGGATGCACTCTTAAATATA
CATCTAATACGATTATTCAATTTACTGTTGGATTTAATGAAGACCAAGAA
TTACCTAACGTCTACTTGAACTTTCATGCTGCACTCGAAAAAATTCGTAA
TAATGCTAATAACGATATAAGAGGACCACGTTTAATGATATGTGGAAATG
AAAGTGTAGGGAAAACTACTTTATGTAGAATTTTATCTAATTATGCAGCA
CGCAAGTATAGAAAAGTTATTTTAATTGATGCTAATGTTGGAATGAATGA
CATTTGTTTACCCGGTAGTATAGGTGCTTTAATTGTGACAAAACCATATG
AAGTAGTAGAAGGTTGGGATATATTTGAGGATCCTTTAATTTACAGTTTT
GGACATTTGTCCCCTGTTGAAAATTTGAAATTATTTTCGTTGCAATTGAA
TAATCTTGCTGAACTTGTTAATATCAGATCCGAAAACGACCCTGAAGTTT
TCGCGGGAGGTTGCATCATTAACATGAGTGGTGTCAGTAAATCTGATGAC
TCTGGTGAATCACAAAAAAAAGGCATTGAAGCTATTCGAGCCGCTATTTC
AGCATTTGAAGTGAATCTCCTTATTATAATCGAAGATGGGTTTCTCGAAA
ATTTATTGCGAAAAGATTTACCCGACTACGTTAGTGTTATTAGAATTCCG
AAATCTTCTGGTGCCCACTCAAGAACTCCTGAACAATGGCAGAAAGAACG
AACTTCTAATATCGCTTCTTACTTTCATGGTCGAGGTTTGCATAAACTCC
AACCTCATAAACTGACATTATTGGCAGAAAATTATAAAATATACAAAATC
GATTTGAAAAAATCTACGTTGGCATTGTTGCCAAATGATGATACAATGGA
AGATGAGTGGTGCAAATTGGTAGAAGTGCCTTTCAGTCGGTCGCTATCTA
ACAGAGTATTGGCAGTATCTGAAGCCCTTGATGTAGACGAGATTCCTGGA
GCTGCGTGTTATGGATTTGTAGTTGTGCTGAGCGTAGCGCCAGATAATTC
CAGCATTACCGTCCTCAGTCCAGGTAACGATGAACCTCCAAACAACATTT
TAGTCATGACAGACATCCAATATGTTGATATGTAAATTGTTGTTAATAAA
ATGTTTTTTT
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protein sequence of SMED30013758-orf-1

>SMED30013758-orf-1 ID=SMED30013758-orf-1|Name=SMED30013758-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=430bp
MTEATDWTEVKLKAQQMMRFECTSVTIIKLVEGSAELFGTELSTKGALNL
QQGFLGTILTFNGCTLKYTSNTIIQFTVGFNEDQELPNVYLNFHAALEKI
RNNANNDIRGPRLMICGNESVGKTTLCRILSNYAARKYRKVILIDANVGM
NDICLPGSIGALIVTKPYEVVEGWDIFEDPLIYSFGHLSPVENLKLFSLQ
LNNLAELVNIRSENDPEVFAGGCIINMSGVSKSDDSGESQKKGIEAIRAA
ISAFEVNLLIIIEDGFLENLLRKDLPDYVSVIRIPKSSGAHSRTPEQWQK
ERTSNIASYFHGRGLHKLQPHKLTLLAENYKIYKIDLKKSTLALLPNDDT
MEDEWCKLVEVPFSRSLSNRVLAVSEALDVDEIPGAACYGFVVVLSVAPD
NSSITVLSPGNDEPPNNILVMTDIQYVDM*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: molecular function
TermDefinition
GO:0016301kinase activity
GO:0000166nucleotide binding
GO:0005524ATP binding
Vocabulary: biological process
TermDefinition
GO:0016310phosphorylation
GO:0031124mRNA 3'-end processing
GO:0006397mRNA processing
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000099neuron
PLANA:0002109X1 cell
PLANA:0002111X2 cell
Vocabulary: INTERPRO
TermDefinition
IPR038239Clp1_N_sf
IPR038238Clp1_C_sf
IPR032319CLP1_P
IPR027417P-loop_NTPase
IPR010655Clp1_C
IPR032324Clp1_N
Vocabulary: cellular component
TermDefinition
GO:0005634nucleus
GO:0005849mRNA cleavage factor complex
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR038239Clp1, N-terminal beta-sandwich domain superfamilyGENE3DG3DSA:2.60.120.1030coord: 1..79
e-value: 6.8E-12
score: 46.9
IPR032324Clp1, N-terminal beta-sandwich domainPFAMPF16573CLP1_Ncoord: 11..104
e-value: 1.3E-15
score: 57.4
IPR010655Pre-mRNA cleavage complex subunit Clp1, C-terminalPFAMPF06807Clp1coord: 318..428
e-value: 5.4E-16
score: 59.1
IPR032319Polyribonucleotide 5'-hydroxyl-kinase Clp1, P-loop domainPFAMPF16575CLP1_Pcoord: 117..312
e-value: 4.2E-42
score: 144.1
IPR038238Clp1, C-terminal domain superfamilyGENE3DG3DSA:3.30.70.2410coord: 320..429
e-value: 3.8E-21
score: 77.4
NoneNo IPR availableGENE3DG3DSA:3.40.50.300coord: 88..318
e-value: 1.6E-62
score: 212.8
NoneNo IPR availablePANTHERPTHR12755:SF6POLYRIBONUCLEOTIDE 5'-HYDROXYL-KINASE CLP1coord: 3..429
NoneNo IPR availablePANTHERPTHR12755CLEAVAGE/POLYADENYLATION FACTOR IA SUBUNIT CLP1Pcoord: 3..429
IPR027417P-loop containing nucleoside triphosphate hydrolaseSUPERFAMILYSSF52540P-loop containing nucleoside triphosphate hydrolasescoord: 112..189