SMED30013750

Overview
NameSMED30013750
Smed IDSMED30013750
Length (bp)1253
Neoblast Clusters

Zeng et. al., 2018




▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 



 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)




Explore this single cell expression dataset with our NB Cluster Shiny App




 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of SMED30013750 (SMED30013750) t-SNE clustered cells

Violin plots show distribution of expression levels for SMED30013750 (SMED30013750) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of SMED30013750 (SMED30013750) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for SMED30013750 (SMED30013750) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017




Hover the mouse over a column in the graph to view average RPKM values per sample.
Sort Descending | Sort Ascending | Only Non-Zero Values | Tile/Chart | Reset

Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020




SMED30013750

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 4

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
gutSMED30013750SMESG000016699.1 dd_Smed_v4_10468_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
whole organism asexual adult single-cell RNA-sequencing evidence
parenchymal cellSMED30013750SMESG000016699.1 dd_Smed_v4_10468_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
whole organism asexual adult single-cell RNA-sequencing evidence
parenchymal cellSMED30013750SMESG000016699.1 dd_Smed_v4_4932_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
whole organism asexual adult single-cell RNA-sequencing evidence
headSMED30013750SMESG000068601.1 SMESG000016699.1 OX_Smed_1.0.12706ox_Smed_v2PMID:24238224
Kao et al., 2013
whole organism asexual adult RNA-sequencing evidence
Note: Hover over icons to view figure legend
Alignments
SMED30013750 aligns in the following genomic locations:
Alignment LocationAlignment Score
v31.001765:64052..73633 -6190
Homology
BLAST of SMED30013750 vs. Planmine SMEST
Match: SMESG000016699.1 (SMESG000016699.1)

HSP 1 Score: 575.474 bits (1482), Expect = 0.000e+0
Identity = 347/359 (96.66%), Postives = 351/359 (97.77%), Query Frame = 2
Query:  137 HFRNVNEK*LNCLIGNGQKEFKIIGYSDPTKMYRVNSEHTIFCSVKAHKKSFCIFTWNRVIENQNRSIIASSXXXXXXXXXXXXXGYSGYASLSWMSLEKNHRIYNFTLNLKSLNESQEGYYSCHITESSANSEXXXXXXXXXXXXNMIFLVIELIVSFIVILAILRAFQYDXXXXXXXXXXXXXXXXXXSXXXXXXXXXXXECENEFQVIDRIVKELENRGFSSYFYHRDKIYGRDTIEDITQKLKNADLIVIWASENMWENSTCNFCMQIILNRFCNIKRIYIMTSRTKLVLKTCESKQVLIDTKSCLSSKRFRCNLDVISKDQDRTNYSETWYWHYFLSWLISSLPLESVCKDNTL 1213
            H  N+    ++  +GNGQKEFKIIGYSDPTKMYRVNSEHTIFCSVKAHKKSFCIFTWNRVIENQNRSIIASSNLTTDRTNDTLTNGYSGYASLSWMSLEKNHRIYNFTLNLKSLNESQEGYYSCHITESSANSELLHLFHFRLYRRNMIFLVIELIVSFIVILAILRAFQYDIKIIIFQIIRKFIKQKNISNNYNFLFLYNFECENEFQVIDRIVKELENRGFSSYFYHRDKIYGRDTIEDITQKLKNADLIVIWASENMWENSTCNFCMQIILNRFCNIKRIYIMTSRTKLVLKTCESKQVLIDTKSCLSSKRFRCNLDVISKDQDRTNYSETWYWHYFLSWLISSLPLESVCKDNTL
Sbjct:   75 HSNNLISAEISLYVGNGQKEFKIIGYSDPTKMYRVNSEHTIFCSVKAHKKSFCIFTWNRVIENQNRSIIASSNLTTDRTNDTLTNGYSGYASLSWMSLEKNHRIYNFTLNLKSLNESQEGYYSCHITESSANSELLHLFHFRLYRRNMIFLVIELIVSFIVILAILRAFQYDIKIIIFQIIRKFIKQKNISNNYNFLFLYNFECENEFQVIDRIVKELENRGFSSYFYHRDKIYGRDTIEDITQKLKNADLIVIWASENMWENSTCNFCMQIILNRFCNIKRIYIMTSRTKLVLKTCESKQVLIDTKSCLSSKRFRCNLDVISKDQDRTNYSETWYWHYFLSWLISSLPLESVCKDNTL 433          
BLAST of SMED30013750 vs. Planmine SMEST
Match: SMESG000016699.1 (SMESG000016699.1)

HSP 1 Score: 264.618 bits (675), Expect = 1.800e-86
Identity = 160/172 (93.02%), Postives = 164/172 (95.35%), Query Frame = 2
Query:  137 HFRNVNEK*LNCLIGNGQKEFKIIGYSDPTKMYRVNSEHTIFCSVKAHKKSFCIFTWNRVIENQNRSIIASSXXXXXXXXXXXXXGYSGYASLSWMSLEKNHRIYNFTLNLKSLNESQEGYYSCHITESSANSEXXXXXXXXXXXXNMIFLVIELIVSFIVILAILRAFQYD 652
            H  N+    ++  +GNGQKEFKIIGYSDPTKMYRVNSEHTIFCSVKAHKKSFCIFTWNRVIENQNRSIIASSNLTTDRTNDTLTNGYSGYASLSWMSLEKNHRIYNFTLNLKSLNESQEGYYSCHITESSANSELLHLFHFRLYRRNMIFLVIELIVSFIVILAILRAFQYD
Sbjct:   75 HSNNLISAEISLYVGNGQKEFKIIGYSDPTKMYRVNSEHTIFCSVKAHKKSFCIFTWNRVIENQNRSIIASSNLTTDRTNDTLTNGYSGYASLSWMSLEKNHRIYNFTLNLKSLNESQEGYYSCHITESSANSELLHLFHFRLYRRNMIFLVIELIVSFIVILAILRAFQYD 246          
BLAST of SMED30013750 vs. Planmine SMEST
Match: SMESG000016701.1 (SMESG000016701.1)

HSP 1 Score: 169.859 bits (429), Expect = 1.117e-47
Identity = 120/336 (35.71%), Postives = 197/336 (58.63%), Query Frame = 2
Query:  191 KEFKIIGYSDPTKMYRVN-SEHTIFCSVKAHKKSFCIFTWNRVIENQNRSIIASSXXXXXXXXXXXXXGYSGYASLSWMSLEKNHRIYNFTLNLKSLNESQEGYYSCHITESSANSEXXXXXXXXXXXXNMIFLVIELIVSFIVILAILRAFQYDXXXXXXXXXXXXXXXXXXSXXXXXXXXXXXECENEFQVIDRIVKELENRGFSSYFYHRDKIYGRDTIEDITQKLKNADLIVIWASENMWENSTCNFCMQIILNRFCNIKRIYIMTSRTKLVLKTCESKQVLIDTKSCLSSKRFRCNLDVISKDQDRTNYSETWYWHYFLSWLISSLPLESV 1195
            K+ +I+  SD T++  V  S +T +C VK    S C F+WNR    +  SI+A SNLT  RT DTL  GYSGY+ L  ++ + N R + F L + ++  S EG YSC + +     E +   + +L  +  I++   ++  FI+I  +   FQYD KI++ + ++    ++    +YNF FLY+F+ E  FQ I ++VK++E+R  + YFYHRD+IYG+   E++ +KL+ +D+IV W S+ +W+N   +FC+Q+++  +    R+YIMTS  +  ++ C S  +  D KS + S  +  N+        ++ +S+ W WH   SWLISSLP+ S+
Sbjct:  144 KDIEIVDASDITELTFVPYSNYTFYCLVKVFPGSICNFSWNRKKNGKRTSILAHSNLTKKRTYDTLVEGYSGYSQLKELNKQGNFRNFLFELIIFNIQTSHEGEYSCLVEDRFEKDERVFNVYVKLLGKEHIYIASGIVGCFILIFILAYEFQYDCKILLKKSLQFLTIKEKNFGSYNFFFLYDFDDEYTFQTIAKVVKKIESRYCTVYFYHRDQIYGKIMFEELYEKLQRSDVIVFWVSQKIWKNPISSFCIQMLIRNYPKKTRLYIMTSNKQNAMENCNSSMISADIKSWILSNIYFWNI-------KKSKFSKLWRWHNLSSWLISSLPVHSL 472          
BLAST of SMED30013750 vs. Planmine SMEST
Match: SMESG000016701.1 (SMESG000016701.1)

HSP 1 Score: 169.859 bits (429), Expect = 1.149e-47
Identity = 120/336 (35.71%), Postives = 197/336 (58.63%), Query Frame = 2
Query:  191 KEFKIIGYSDPTKMYRVN-SEHTIFCSVKAHKKSFCIFTWNRVIENQNRSIIASSXXXXXXXXXXXXXGYSGYASLSWMSLEKNHRIYNFTLNLKSLNESQEGYYSCHITESSANSEXXXXXXXXXXXXNMIFLVIELIVSFIVILAILRAFQYDXXXXXXXXXXXXXXXXXXSXXXXXXXXXXXECENEFQVIDRIVKELENRGFSSYFYHRDKIYGRDTIEDITQKLKNADLIVIWASENMWENSTCNFCMQIILNRFCNIKRIYIMTSRTKLVLKTCESKQVLIDTKSCLSSKRFRCNLDVISKDQDRTNYSETWYWHYFLSWLISSLPLESV 1195
            K+ +I+  SD T++  V  S +T +C VK    S C F+WNR    +  SI+A SNLT  RT DTL  GYSGY+ L  ++ + N R + F L + ++  S EG YSC + +     E +   + +L  +  I++   ++  FI+I  +   FQYD KI++ + ++    ++    +YNF FLY+F+ E  FQ I ++VK++E+R  + YFYHRD+IYG+   E++ +KL+ +D+IV W S+ +W+N   +FC+Q+++  +    R+YIMTS  +  ++ C S  +  D KS + S  +  N+        ++ +S+ W WH   SWLISSLP+ S+
Sbjct:  140 KDIEIVDASDITELTFVPYSNYTFYCLVKVFPGSICNFSWNRKKNGKRTSILAHSNLTKKRTYDTLVEGYSGYSQLKELNKQGNFRNFLFELIIFNIQTSHEGEYSCLVEDRFEKDERVFNVYVKLLGKEHIYIASGIVGCFILIFILAYEFQYDCKILLKKSLQFLTIKEKNFGSYNFFFLYDFDDEYTFQTIAKVVKKIESRYCTVYFYHRDQIYGKIMFEELYEKLQRSDVIVFWVSQKIWKNPISSFCIQMLIRNYPKKTRLYIMTSNKQNAMENCNSSMISADIKSWILSNIYFWNI-------KKSKFSKLWRWHNLSSWLISSLPVHSL 468          
BLAST of SMED30013750 vs. Planmine SMEST
Match: SMESG000016701.1 (SMESG000016701.1)

HSP 1 Score: 169.859 bits (429), Expect = 1.650e-47
Identity = 120/336 (35.71%), Postives = 197/336 (58.63%), Query Frame = 2
Query:  191 KEFKIIGYSDPTKMYRVN-SEHTIFCSVKAHKKSFCIFTWNRVIENQNRSIIASSXXXXXXXXXXXXXGYSGYASLSWMSLEKNHRIYNFTLNLKSLNESQEGYYSCHITESSANSEXXXXXXXXXXXXNMIFLVIELIVSFIVILAILRAFQYDXXXXXXXXXXXXXXXXXXSXXXXXXXXXXXECENEFQVIDRIVKELENRGFSSYFYHRDKIYGRDTIEDITQKLKNADLIVIWASENMWENSTCNFCMQIILNRFCNIKRIYIMTSRTKLVLKTCESKQVLIDTKSCLSSKRFRCNLDVISKDQDRTNYSETWYWHYFLSWLISSLPLESV 1195
            K+ +I+  SD T++  V  S +T +C VK    S C F+WNR    +  SI+A SNLT  RT DTL  GYSGY+ L  ++ + N R + F L + ++  S EG YSC + +     E +   + +L  +  I++   ++  FI+I  +   FQYD KI++ + ++    ++    +YNF FLY+F+ E  FQ I ++VK++E+R  + YFYHRD+IYG+   E++ +KL+ +D+IV W S+ +W+N   +FC+Q+++  +    R+YIMTS  +  ++ C S  +  D KS + S  +  N+        ++ +S+ W WH   SWLISSLP+ S+
Sbjct:  162 KDIEIVDASDITELTFVPYSNYTFYCLVKVFPGSICNFSWNRKKNGKRTSILAHSNLTKKRTYDTLVEGYSGYSQLKELNKQGNFRNFLFELIIFNIQTSHEGEYSCLVEDRFEKDERVFNVYVKLLGKEHIYIASGIVGCFILIFILAYEFQYDCKILLKKSLQFLTIKEKNFGSYNFFFLYDFDDEYTFQTIAKVVKKIESRYCTVYFYHRDQIYGKIMFEELYEKLQRSDVIVFWVSQKIWKNPISSFCIQMLIRNYPKKTRLYIMTSNKQNAMENCNSSMISADIKSWILSNIYFWNI-------KKSKFSKLWRWHNLSSWLISSLPVHSL 490          
The following BLAST results are available for this feature:
BLAST of SMED30013750 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of SMED30013750 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of SMED30013750 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of SMED30013750 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of SMED30013750 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of SMED30013750 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of SMED30013750 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of SMED30013750 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of SMED30013750 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of SMED30013750 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of SMED30013750 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of SMED30013750 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of SMED30013750 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of SMED30013750 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5
Match NameE-valueIdentityDescription
SMESG000016699.10.000e+096.66SMESG000016699.1[more]
SMESG000016699.11.800e-8693.02SMESG000016699.1[more]
SMESG000016701.11.117e-4735.71SMESG000016701.1[more]
SMESG000016701.11.149e-4735.71SMESG000016701.1[more]
SMESG000016701.11.650e-4735.71SMESG000016701.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30013750 ID=SMED30013750|Name=SMED30013750|organism=Schmidtea mediterranea sexual|type=transcript|length=1253bp
CATTATTATCTATTGCAATTCAGACTTCACTTATCGCCATTTGATGTATA
TTATAGATGTGTTTATTCATGCAAACAATTGTATAATTAATTTTTAAAAA
ACAATTATTATTTTGGGTATATTTTGTTTCAGAATGCATTTTCGAAATGT
AAATGAGAAATAATTAAATTGTCTTATAGGAAATGGTCAGAAAGAATTTA
AAATAATTGGATATAGTGATCCGACCAAAATGTATAGAGTCAATTCAGAG
CATACAATATTCTGTTCAGTGAAAGCCCATAAAAAATCATTTTGCATTTT
TACATGGAATAGAGTAATAGAAAATCAAAATCGGTCTATCATTGCAAGCT
CCAATTTAACAACGGACAGGACCAATGATACCCTTACCAATGGCTATTCT
GGATACGCAAGTTTGAGCTGGATGTCATTAGAAAAGAATCATCGGATTTA
TAATTTTACTTTGAATTTGAAGAGTCTTAACGAATCTCAGGAAGGTTATT
ACAGTTGTCATATTACTGAAAGTTCAGCGAATTCGGAACTTCTGCATTTA
TTTCATTTCCGATTGTACAGAAGAAATATGATATTTCTGGTTATTGAATT
AATTGTCAGTTTCATTGTTATATTGGCTATTTTGCGCGCATTCCAATATG
ATATTAAGATTATTATCTTTCAAATTATTCGCAAGTTTATTAAGCAAAAA
AATATTTCAAACAATTACAATTTCTTATTTCTCTACAATTTTGAATGTGA
AAATGAATTCCAAGTCATCGACAGAATAGTCAAAGAATTAGAAAACCGAG
GATTTTCTTCATATTTTTATCATCGAGATAAAATTTACGGAAGAGATACA
ATTGAAGATATTACTCAAAAATTGAAAAATGCTGATTTAATAGTAATTTG
GGCTTCTGAAAATATGTGGGAAAATTCAACGTGCAATTTCTGCATGCAAA
TTATTTTAAATAGATTCTGTAATATAAAACGAATATATATAATGACATCA
AGAACAAAACTTGTACTAAAAACCTGTGAAAGTAAACAAGTATTAATAGA
TACAAAGTCCTGCCTGTCATCCAAACGTTTCCGATGCAACTTAGATGTTA
TTAGCAAGGACCAAGACAGAACAAACTATTCAGAAACATGGTACTGGCAT
TATTTCCTTTCATGGTTAATTTCTTCTCTTCCTTTGGAATCGGTATGCAA
AGACAATACTCTTTAATAAACATATTGTACAAAAACTTTAATAAATTTTG
TCG
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protein sequence of SMED30013750-orf-1

>SMED30013750-orf-1 ID=SMED30013750-orf-1|Name=SMED30013750-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=329bp
MYRVNSEHTIFCSVKAHKKSFCIFTWNRVIENQNRSIIASSNLTTDRTND
TLTNGYSGYASLSWMSLEKNHRIYNFTLNLKSLNESQEGYYSCHITESSA
NSELLHLFHFRLYRRNMIFLVIELIVSFIVILAILRAFQYDIKIIIFQII
RKFIKQKNISNNYNFLFLYNFECENEFQVIDRIVKELENRGFSSYFYHRD
KIYGRDTIEDITQKLKNADLIVIWASENMWENSTCNFCMQIILNRFCNIK
RIYIMTSRTKLVLKTCESKQVLIDTKSCLSSKRFRCNLDVISKDQDRTNY
SETWYWHYFLSWLISSLPLESVCKDNTL*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000026gut
PLANA:0000418head
PLANA:0003116parenchymal cell
Vocabulary: INTERPRO
TermDefinition
IPR035897Toll_tir_struct_dom_sf
IPR036179Ig-like_dom_sf
IPR013783Ig-like_fold
IPR000157TIR_dom
IPR007110Ig-like_dom
Vocabulary: biological process
TermDefinition
GO:0007165signal transduction
Vocabulary: molecular function
TermDefinition
GO:0005515protein binding
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR035897Toll/interleukin-1 receptor homology (TIR) domain superfamilyGENE3DG3DSA:3.40.50.10140coord: 154..313
e-value: 2.2E-9
score: 39.1
IPR035897Toll/interleukin-1 receptor homology (TIR) domain superfamilySUPERFAMILYSSF52200Toll/Interleukin receptor TIR domaincoord: 172..254
IPR013783Immunoglobulin-like foldGENE3DG3DSA:2.60.40.10coord: 3..107
e-value: 7.2E-6
score: 28.3
IPR007110Immunoglobulin-like domainPROSITEPS50835IG_LIKEcoord: 1..105
score: 6.615
IPR036179Immunoglobulin-like domain superfamilySUPERFAMILYSSF48726Immunoglobulincoord: 3..97
NoneNo IPR availableTMHMMTMhelixcoord: 118..140