Centrin

Overview
NameCentrin
Smed IDSMED30013731
Length (bp)542
Neoblast Clusters

Zeng et. al., 2018



▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)



Explore this single cell expression dataset with our NB Cluster Shiny App



 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of Centrin (SMED30013731) t-SNE clustered cells

Violin plots show distribution of expression levels for Centrin (SMED30013731) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of Centrin (SMED30013731) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for Centrin (SMED30013731) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020



SMED30013731

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 10

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
head regionSMED30013731SMESG000040368.1 SmedASXL_019529SmedAsxl_ww_GCZZ01PMID:27034770
Currie et al., 2016		whole organism asexual adult RNA-sequencing evidence
pharynxSMED30013731SMESG000040368.1 dd_Smed_v4_7903_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
protonephridiaSMED30013731SMESG000040368.1 dd_Smed_v4_7903_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
nervous systemSMED30013731SMESG000040368.1 dd_Smed_v4_7903_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
epidermisSMED30013731SMESG000040368.1 dd_Smed_v4_7903_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
cephalic gangliaSMED30013731SMESG000040368.1 dd_Smed_v4_7903_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
neuronSMED30013731SMESG000040368.1 dd_Smed_v4_7903_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		whole organism asexual adult colorimetric in situ hybridization evidence
cilated neuronSMED30013731SMESG000040368.1 dd_Smed_v4_7903_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
head regionSMED30013731SMESG000040368.1 dd_Smed_v6_7903_0_1dd_Smed_v6PMID:28171748
Stückemann et al., 2017		whole organism asexual adult RNA-sequencing evidence
epidermisSMED30013731SMESG000040368.1 dd_Smed_v4_7903_0_1dd_Smed_v4PMID:28292427
Wurtzel et al., 2017		whole organism asexual adult single-cell RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
[Close]
BLAST of Centrin vs. Ensembl Human
Match: CETN2 (centrin 2 [Source:HGNC Symbol;Acc:HGNC:1867])

HSP 1 Score: 180.259 bits (456), Expect = 7.723e-58
Identity = 88/149 (59.06%), Postives = 121/149 (81.21%), Query Frame = 2 
Query:   86 ELSEKQKEDIQKAFNLFDKDGSGTIDIQEVKVALRALDFEPLKDDIRKLISEYDKDNKGTIDFNNFLILISSKMTEPDSKEDITKAFNLFDKDGKEKISIHNLKSISEILGENLTDEELQEMLFNADRDNPGEVNERDFHRIMKKNSFY 532
            EL+E+QK++I++AF+LFD DG+GTID++E+KVA+RAL FEP K++I+K+ISE DK+  G ++F +FL +++ KM+E D+KE+I KAF LFD D   KIS  NLK +++ LGENLTDEELQEM+  ADRD  GEV+E++F RIMKK S Y
Sbjct:   24 ELTEEQKQEIREAFDLFDADGTGTIDVKELKVAMRALGFEPKKEEIKKMISEIDKEGTGKMNFGDFLTVMTQKMSEKDTKEEILKAFKLFDDDETGKISFKNLKRVAKELGENLTDEELQEMIDEADRDGDGEVSEQEFLRIMKKTSLY 172
[Close]
BLAST of Centrin vs. Ensembl Human
Match: CETN1 (centrin 1 [Source:HGNC Symbol;Acc:HGNC:1866])

HSP 1 Score: 179.489 bits (454), Expect = 1.752e-57
Identity = 89/149 (59.73%), Postives = 117/149 (78.52%), Query Frame = 2 
Query:   86 ELSEKQKEDIQKAFNLFDKDGSGTIDIQEVKVALRALDFEPLKDDIRKLISEYDKDNKGTIDFNNFLILISSKMTEPDSKEDITKAFNLFDKDGKEKISIHNLKSISEILGENLTDEELQEMLFNADRDNPGEVNERDFHRIMKKNSFY 532
            EL+E QK+++++AF+LFD DGSGTID +E+KVA+RAL FEP K++++K+ISE D++  G I FN+FL +++ KM+E D+KE+I KAF LFD D   KIS  NLK ++  LGENLTDEELQEM+  ADRD  GEVNE +F RIMKK S Y
Sbjct:   24 ELTEDQKQEVREAFDLFDVDGSGTIDAKELKVAMRALGFEPRKEEMKKMISEVDREGTGKISFNDFLAVMTQKMSEKDTKEEILKAFRLFDDDETGKISFKNLKRVANELGENLTDEELQEMIDEADRDGDGEVNEEEFLRIMKKTSLY 172
[Close]
BLAST of Centrin vs. Ensembl Human
Match: CALM2 (calmodulin 2 [Source:HGNC Symbol;Acc:HGNC:1445])

HSP 1 Score: 124.02 bits (310), Expect = 4.942e-36
Identity = 64/146 (43.84%), Postives = 97/146 (66.44%), Query Frame = 2 
Query:   77 MTIELSEKQKEDIQKAFNLFDKDGSGTIDIQEVKVALRALDFEPLKDDIRKLISEYDKDNKGTIDFNNFLILISSKMTEPDSKEDITKAFNLFDKDGKEKISIHNLKSISEILGENLTDEELQEMLFNADRDNPGEVNERDFHRIM 514
            M  +L+E+Q  + ++AF+LFDKDG GTI  +E+   +R+L   P + +++ +I+E D D  GTIDF  FL +++ KM + DS+E+I +AF +FDKDG   IS   L+ +   LGE LTDEE+ EM+  AD D  G+VN  +F ++M
Sbjct:    1 MADQLTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVQMM 146

HSP 2 Score: 46.2098 bits (108), Expect = 3.885e-6
Identity = 23/61 (37.70%), Postives = 37/61 (60.66%), Query Frame = 2 
Query:  338 KAFNLFDKDGKEKISIHNLKSISEILGENLTDEELQEMLFNADRDNPGEVNERDFHRIMKK 520
            +AF+LFDKDG   I+   L ++   LG+N T+ ELQ+M+   D D  G ++  +F  +M +
Sbjct:   15 EAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPEFLTMMAR 75
[Close]
BLAST of Centrin vs. Ensembl Human
Match: CALM2 (calmodulin 2 [Source:HGNC Symbol;Acc:HGNC:1445])

HSP 1 Score: 124.02 bits (310), Expect = 4.942e-36
Identity = 64/146 (43.84%), Postives = 97/146 (66.44%), Query Frame = 2 
Query:   77 MTIELSEKQKEDIQKAFNLFDKDGSGTIDIQEVKVALRALDFEPLKDDIRKLISEYDKDNKGTIDFNNFLILISSKMTEPDSKEDITKAFNLFDKDGKEKISIHNLKSISEILGENLTDEELQEMLFNADRDNPGEVNERDFHRIM 514
            M  +L+E+Q  + ++AF+LFDKDG GTI  +E+   +R+L   P + +++ +I+E D D  GTIDF  FL +++ KM + DS+E+I +AF +FDKDG   IS   L+ +   LGE LTDEE+ EM+  AD D  G+VN  +F ++M
Sbjct:    1 MADQLTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVQMM 146

HSP 2 Score: 46.2098 bits (108), Expect = 3.885e-6
Identity = 23/61 (37.70%), Postives = 37/61 (60.66%), Query Frame = 2 
Query:  338 KAFNLFDKDGKEKISIHNLKSISEILGENLTDEELQEMLFNADRDNPGEVNERDFHRIMKK 520
            +AF+LFDKDG   I+   L ++   LG+N T+ ELQ+M+   D D  G ++  +F  +M +
Sbjct:   15 EAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPEFLTMMAR 75
[Close]
BLAST of Centrin vs. Ensembl Human
Match: CALM1 (calmodulin 1 [Source:HGNC Symbol;Acc:HGNC:1442])

HSP 1 Score: 124.02 bits (310), Expect = 4.942e-36
Identity = 64/146 (43.84%), Postives = 97/146 (66.44%), Query Frame = 2 
Query:   77 MTIELSEKQKEDIQKAFNLFDKDGSGTIDIQEVKVALRALDFEPLKDDIRKLISEYDKDNKGTIDFNNFLILISSKMTEPDSKEDITKAFNLFDKDGKEKISIHNLKSISEILGENLTDEELQEMLFNADRDNPGEVNERDFHRIM 514
            M  +L+E+Q  + ++AF+LFDKDG GTI  +E+   +R+L   P + +++ +I+E D D  GTIDF  FL +++ KM + DS+E+I +AF +FDKDG   IS   L+ +   LGE LTDEE+ EM+  AD D  G+VN  +F ++M
Sbjct:    1 MADQLTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVQMM 146

HSP 2 Score: 46.2098 bits (108), Expect = 3.885e-6
Identity = 23/61 (37.70%), Postives = 37/61 (60.66%), Query Frame = 2 
Query:  338 KAFNLFDKDGKEKISIHNLKSISEILGENLTDEELQEMLFNADRDNPGEVNERDFHRIMKK 520
            +AF+LFDKDG   I+   L ++   LG+N T+ ELQ+M+   D D  G ++  +F  +M +
Sbjct:   15 EAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPEFLTMMAR 75
[Close]
BLAST of Centrin vs. Ensembl Celegans
Match: cmd-1 (Calmodulin [Source:UniProtKB/Swiss-Prot;Acc:O16305])

HSP 1 Score: 122.094 bits (305), Expect = 1.026e-35
Identity = 64/146 (43.84%), Postives = 96/146 (65.75%), Query Frame = 2 
Query:   77 MTIELSEKQKEDIQKAFNLFDKDGSGTIDIQEVKVALRALDFEPLKDDIRKLISEYDKDNKGTIDFNNFLILISSKMTEPDSKEDITKAFNLFDKDGKEKISIHNLKSISEILGENLTDEELQEMLFNADRDNPGEVNERDFHRIM 514
            M  +L+E+Q  + ++AF+LFDKDG GTI  +E+   +R+L   P + +++ +I+E D D  GTIDF  FL +++ KM + DS+E+I +AF +FDKDG   IS   L+ +   LGE LTDEE+ EM+  AD D  G+VN  +F  +M
Sbjct:    1 MADQLTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGFISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVTMM 146

HSP 2 Score: 46.2098 bits (108), Expect = 1.354e-6
Identity = 23/61 (37.70%), Postives = 37/61 (60.66%), Query Frame = 2 
Query:  338 KAFNLFDKDGKEKISIHNLKSISEILGENLTDEELQEMLFNADRDNPGEVNERDFHRIMKK 520
            +AF+LFDKDG   I+   L ++   LG+N T+ ELQ+M+   D D  G ++  +F  +M +
Sbjct:   15 EAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPEFLTMMAR 75

HSP 3 Score: 44.2838 bits (103), Expect = 6.378e-6
Identity = 20/67 (29.85%), Postives = 43/67 (64.18%), Query Frame = 2 
Query:  104 KEDIQKAFNLFDKDGSGTIDIQEVKVALRALDFEPLKDDIRKLISEYDKDNKGTIDFNNFLILISSK 304
            +E+I++AF +FDKDG+G I   E++  +  L  +   +++ ++I E D D  G +++  F+ ++++K
Sbjct:   83 EEEIREAFRVFDKDGNGFISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVTMMTTK 149
[Close]
BLAST of Centrin vs. Ensembl Celegans
Match: cal-1 (Calmodulin-like protein [Source:UniProtKB/Swiss-Prot;Acc:P04630])

HSP 1 Score: 95.1301 bits (235), Expect = 5.442e-25
Identity = 50/143 (34.97%), Postives = 88/143 (61.54%), Query Frame = 2 
Query:   86 ELSEKQKEDIQKAFNLFDKDGSGTIDIQEVKVALRALDFEPLKDDIRKLISEYDKDNKGTIDFNNFLILISSKMTEPDSKEDITKAFNLFDKDGKEKISIHNLKSISEILGENLTDEELQEMLFNADRDNPGEVNERDFHRIM 514
            +L+ ++ ++ ++AF +FDKDG+GTI  +E+ +A+R+L   P + +I ++I+E D D  G I+F  F +++   M E DS E I +AF +FDKDG   I+    +     +G   ++EE+ EM+   D D  GE++  +F ++M
Sbjct:   17 QLTPEEIDEFREAFMMFDKDGNGTISTKELGIAMRSLGQNPTEQEILEMINEVDIDGNGQIEFPEFCVMMKRMMKETDS-EMIREAFRVFDKDGNGVITAQEFRYFMVHMGMQFSEEEVDEMIKEVDVDGDGEIDYEEFVKMM 158

HSP 2 Score: 48.1358 bits (113), Expect = 3.209e-7
Identity = 23/72 (31.94%), Postives = 44/72 (61.11%), Query Frame = 2 
Query:   89 LSEKQKEDIQKAFNLFDKDGSGTIDIQEVKVALRALDFEPLKDDIRKLISEYDKDNKGTIDFNNFLILISSK 304
            + E   E I++AF +FDKDG+G I  QE +  +  +  +  ++++ ++I E D D  G ID+  F+ ++S++
Sbjct:   90 MKETDSEMIREAFRVFDKDGNGVITAQEFRYFMVHMGMQFSEEEVDEMIKEVDVDGDGEIDYEEFVKMMSNQ 161

HSP 3 Score: 44.2838 bits (103), Expect = 6.651e-6
Identity = 25/73 (34.25%), Postives = 40/73 (54.79%), Query Frame = 2 
Query:  302 KMTEPDSKEDITKAFNLFDKDGKEKISIHNLKSISEILGENLTDEELQEMLFNADRDNPGEVNERDFHRIMKK 520
            K   P+  ++  +AF +FDKDG   IS   L      LG+N T++E+ EM+   D D  G++   +F  +MK+
Sbjct:   16 KQLTPEEIDEFREAFMMFDKDGNGTISTKELGIAMRSLGQNPTEQEILEMINEVDIDGNGQIEFPEFCVMMKR 88
[Close]
BLAST of Centrin vs. Ensembl Celegans
Match: cal-1 (Calmodulin-like protein [Source:UniProtKB/Swiss-Prot;Acc:P04630])

HSP 1 Score: 95.1301 bits (235), Expect = 9.438e-25
Identity = 50/143 (34.97%), Postives = 88/143 (61.54%), Query Frame = 2 
Query:   86 ELSEKQKEDIQKAFNLFDKDGSGTIDIQEVKVALRALDFEPLKDDIRKLISEYDKDNKGTIDFNNFLILISSKMTEPDSKEDITKAFNLFDKDGKEKISIHNLKSISEILGENLTDEELQEMLFNADRDNPGEVNERDFHRIM 514
            +L+ ++ ++ ++AF +FDKDG+GTI  +E+ +A+R+L   P + +I ++I+E D D  G I+F  F +++   M E DS E I +AF +FDKDG   I+    +     +G   ++EE+ EM+   D D  GE++  +F ++M
Sbjct:   36 QLTPEEIDEFREAFMMFDKDGNGTISTKELGIAMRSLGQNPTEQEILEMINEVDIDGNGQIEFPEFCVMMKRMMKETDS-EMIREAFRVFDKDGNGVITAQEFRYFMVHMGMQFSEEEVDEMIKEVDVDGDGEIDYEEFVKMM 177

HSP 2 Score: 47.7506 bits (112), Expect = 4.701e-7
Identity = 23/72 (31.94%), Postives = 44/72 (61.11%), Query Frame = 2 
Query:   89 LSEKQKEDIQKAFNLFDKDGSGTIDIQEVKVALRALDFEPLKDDIRKLISEYDKDNKGTIDFNNFLILISSK 304
            + E   E I++AF +FDKDG+G I  QE +  +  +  +  ++++ ++I E D D  G ID+  F+ ++S++
Sbjct:  109 MKETDSEMIREAFRVFDKDGNGVITAQEFRYFMVHMGMQFSEEEVDEMIKEVDVDGDGEIDYEEFVKMMSNQ 180

HSP 3 Score: 44.669 bits (104), Expect = 7.600e-6
Identity = 25/73 (34.25%), Postives = 40/73 (54.79%), Query Frame = 2 
Query:  302 KMTEPDSKEDITKAFNLFDKDGKEKISIHNLKSISEILGENLTDEELQEMLFNADRDNPGEVNERDFHRIMKK 520
            K   P+  ++  +AF +FDKDG   IS   L      LG+N T++E+ EM+   D D  G++   +F  +MK+
Sbjct:   35 KQLTPEEIDEFREAFMMFDKDGNGTISTKELGIAMRSLGQNPTEQEILEMINEVDIDGNGQIEFPEFCVMMKR 107
[Close]
BLAST of Centrin vs. Ensembl Celegans
Match: cmd-1 (Calmodulin [Source:UniProtKB/Swiss-Prot;Acc:O16305])

HSP 1 Score: 91.6633 bits (226), Expect = 3.356e-24
Identity = 48/110 (43.64%), Postives = 71/110 (64.55%), Query Frame = 2 
Query:  185 LRALDFEPLKDDIRKLISEYDKDNKGTIDFNNFLILISSKMTEPDSKEDITKAFNLFDKDGKEKISIHNLKSISEILGENLTDEELQEMLFNADRDNPGEVNERDFHRIM 514
            +R+L   P + +++ +I+E D D  GTIDF  FL +++ KM + DS+E+I +AF +FDKDG   IS   L+ +   LGE LTDEE+ EM+  AD D  G+VN  +F  +M
Sbjct:    1 MRSLGQNPTEAELQDMINEVDADGNGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGFISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVTMM 110

HSP 2 Score: 44.669 bits (104), Expect = 3.124e-6
Identity = 20/67 (29.85%), Postives = 43/67 (64.18%), Query Frame = 2 
Query:  104 KEDIQKAFNLFDKDGSGTIDIQEVKVALRALDFEPLKDDIRKLISEYDKDNKGTIDFNNFLILISSK 304
            +E+I++AF +FDKDG+G I   E++  +  L  +   +++ ++I E D D  G +++  F+ ++++K
Sbjct:   47 EEEIREAFRVFDKDGNGFISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVTMMTTK 113
[Close]
BLAST of Centrin vs. Ensembl Celegans
Match: cal-4 (CALmodulin related genes [Source:UniProtKB/TrEMBL;Acc:G5EDZ8])

HSP 1 Score: 85.1149 bits (209), Expect = 5.969e-21
Identity = 45/130 (34.62%), Postives = 76/130 (58.46%), Query Frame = 2 
Query:   86 ELSEKQKEDIQKAFNLFDKDGSGTIDIQEVKVALRALDFEPLKDDIRKLISEYDKDNKGTIDFNNFLILISSKMTEPDSKEDITKAFNLFDKDGKEKISIHNLKSISEILGENLTDEELQEMLFNADRDN 475
            E + ++ ++  +AF LFDKDG+ T++I+E+  A+R L   P ++++  +++EYD D  G IDF  F  ++     E D +E I  AF +FDKDG   I+    K     +GE  ++EE+ E++   D+D 
Sbjct:   16 EFTPEELQEFAQAFKLFDKDGNNTMNIKELGEAMRMLGLNPTEEELLNMVNEYDVDGNGKIDFGEFCKMMKEMNKETD-QELIRLAFKVFDKDGNGYITAQEFKHFMTTMGERFSEEEVDEIIREVDKDG 144

HSP 2 Score: 46.9802 bits (110), Expect = 1.171e-6
Identity = 25/69 (36.23%), Postives = 41/69 (59.42%), Query Frame = 2 
Query:  314 PDSKEDITKAFNLFDKDGKEKISIHNLKSISEILGENLTDEELQEMLFNADRDNPGEVNERDFHRIMKK 520
            P+  ++  +AF LFDKDG   ++I  L     +LG N T+EEL  M+   D D  G+++  +F ++MK+
Sbjct:   19 PEELQEFAQAFKLFDKDGNNTMNIKELGEAMRMLGLNPTEEELLNMVNEYDVDGNGKIDFGEFCKMMKE 87
[Close]
BLAST of Centrin vs. Ensembl Fly
Match: CG17493 (gene:FBgn0040010 transcript:FBtr0332630)

HSP 1 Score: 168.318 bits (425), Expect = 2.931e-53
Identity = 87/149 (58.39%), Postives = 113/149 (75.84%), Query Frame = 2 
Query:   86 ELSEKQKEDIQKAFNLFDKDGSGTIDIQEVKVALRALDFEPLKDDIRKLISEYDKDNKGTIDFNNFLILISSKMTEPDSKEDITKAFNLFDKDGKEKISIHNLKSISEILGENLTDEELQEMLFNADRDNPGEVNERDFHRIMKKNSFY 532
            ELSE QK DI++AF+LFD +G+G I+++E+KVA+RAL FEP K++I+++IS+ DKD  G I FN FL L++ KM E D+KE+I KAF LFD D   KIS  NLK ++  LGE LTDEEL+EM+  AD DN GEVN+ +F RIMKK S Y
Sbjct:   34 ELSEAQKCDIKEAFDLFDNEGTGYIEVKELKVAIRALGFEPKKEEIKRMISDIDKDCSGRIAFNVFLQLMTIKMAEKDTKEEILKAFRLFDDDDTGKISFRNLKRVARELGETLTDEELREMIDEADLDNDGEVNQEEFLRIMKKTSLY 182
[Close]
BLAST of Centrin vs. Ensembl Fly
Match: CG17493 (gene:FBgn0040010 transcript:FBtr0332632)

HSP 1 Score: 168.318 bits (425), Expect = 2.931e-53
Identity = 87/149 (58.39%), Postives = 113/149 (75.84%), Query Frame = 2 
Query:   86 ELSEKQKEDIQKAFNLFDKDGSGTIDIQEVKVALRALDFEPLKDDIRKLISEYDKDNKGTIDFNNFLILISSKMTEPDSKEDITKAFNLFDKDGKEKISIHNLKSISEILGENLTDEELQEMLFNADRDNPGEVNERDFHRIMKKNSFY 532
            ELSE QK DI++AF+LFD +G+G I+++E+KVA+RAL FEP K++I+++IS+ DKD  G I FN FL L++ KM E D+KE+I KAF LFD D   KIS  NLK ++  LGE LTDEEL+EM+  AD DN GEVN+ +F RIMKK S Y
Sbjct:   34 ELSEAQKCDIKEAFDLFDNEGTGYIEVKELKVAIRALGFEPKKEEIKRMISDIDKDCSGRIAFNVFLQLMTIKMAEKDTKEEILKAFRLFDDDDTGKISFRNLKRVARELGETLTDEELREMIDEADLDNDGEVNQEEFLRIMKKTSLY 182
[Close]
BLAST of Centrin vs. Ensembl Fly
Match: CG17493 (gene:FBgn0040010 transcript:FBtr0332631)

HSP 1 Score: 168.318 bits (425), Expect = 2.931e-53
Identity = 87/149 (58.39%), Postives = 113/149 (75.84%), Query Frame = 2 
Query:   86 ELSEKQKEDIQKAFNLFDKDGSGTIDIQEVKVALRALDFEPLKDDIRKLISEYDKDNKGTIDFNNFLILISSKMTEPDSKEDITKAFNLFDKDGKEKISIHNLKSISEILGENLTDEELQEMLFNADRDNPGEVNERDFHRIMKKNSFY 532
            ELSE QK DI++AF+LFD +G+G I+++E+KVA+RAL FEP K++I+++IS+ DKD  G I FN FL L++ KM E D+KE+I KAF LFD D   KIS  NLK ++  LGE LTDEEL+EM+  AD DN GEVN+ +F RIMKK S Y
Sbjct:   34 ELSEAQKCDIKEAFDLFDNEGTGYIEVKELKVAIRALGFEPKKEEIKRMISDIDKDCSGRIAFNVFLQLMTIKMAEKDTKEEILKAFRLFDDDDTGKISFRNLKRVARELGETLTDEELREMIDEADLDNDGEVNQEEFLRIMKKTSLY 182
[Close]
BLAST of Centrin vs. Ensembl Fly
Match: CG31802 (gene:FBgn0051802 transcript:FBtr0081058)

HSP 1 Score: 139.428 bits (350), Expect = 7.202e-42
Identity = 74/148 (50.00%), Postives = 103/148 (69.59%), Query Frame = 2 
Query:   80 TIELSEKQKEDIQKAFNLFDKDGSGTIDIQEVKVALRALDFEPLKDDIRKLISEYDKDNKGTIDFNNFLILISSKMTEPDSKEDITKAFNLFDKDGKEKISIHNLKSISEILGENLTDEELQEMLFNADRDNPGEVNERDFHRIMKKN 523
            T +LS  QK DI+KAF+LFD   +G I+ +E++VA+RAL FEP K+DI++++ E DKD  G I FN+FL L+  KM E DS +D+ KAF+ FD D    IS  NLK +++ LGE LTDEELQEM+  A+    GEV++ +F  ++KK 
Sbjct:   36 TFDLSLSQKVDIKKAFDLFDTQCTGFIETKELRVAIRALGFEPKKEDIKRMMDEIDKDKTGRIAFNDFLYLMRLKMAEKDSNQDMMKAFSFFDDDRTGGISFLNLKRVAKELGEQLTDEELQEMIDEANVSGDGEVSKEEFLNLIKKT 183
[Close]
BLAST of Centrin vs. Ensembl Fly
Match: Cam (gene:FBgn0000253 transcript:FBtr0304964)

HSP 1 Score: 122.094 bits (305), Expect = 1.359e-35
Identity = 64/146 (43.84%), Postives = 96/146 (65.75%), Query Frame = 2 
Query:   77 MTIELSEKQKEDIQKAFNLFDKDGSGTIDIQEVKVALRALDFEPLKDDIRKLISEYDKDNKGTIDFNNFLILISSKMTEPDSKEDITKAFNLFDKDGKEKISIHNLKSISEILGENLTDEELQEMLFNADRDNPGEVNERDFHRIM 514
            M  +L+E+Q  + ++AF+LFDKDG GTI  +E+   +R+L   P + +++ +I+E D D  GTIDF  FL +++ KM + DS+E+I +AF +FDKDG   IS   L+ +   LGE LTDEE+ EM+  AD D  G+VN  +F  +M
Sbjct:    1 MADQLTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGFISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVTMM 146

HSP 2 Score: 46.2098 bits (108), Expect = 1.806e-6
Identity = 23/61 (37.70%), Postives = 37/61 (60.66%), Query Frame = 2 
Query:  338 KAFNLFDKDGKEKISIHNLKSISEILGENLTDEELQEMLFNADRDNPGEVNERDFHRIMKK 520
            +AF+LFDKDG   I+   L ++   LG+N T+ ELQ+M+   D D  G ++  +F  +M +
Sbjct:   15 EAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPEFLTMMAR 75

HSP 3 Score: 45.4394 bits (106), Expect = 3.605e-6
Identity = 21/67 (31.34%), Postives = 43/67 (64.18%), Query Frame = 2 
Query:  104 KEDIQKAFNLFDKDGSGTIDIQEVKVALRALDFEPLKDDIRKLISEYDKDNKGTIDFNNFLILISSK 304
            +E+I++AF +FDKDG+G I   E++  +  L  +   +++ ++I E D D  G +++  F+ +++SK
Sbjct:   83 EEEIREAFRVFDKDGNGFISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVTMMTSK 149
[Close]
BLAST of Centrin vs. Ensembl Zebrafish
Match: cetn4 (centrin 4 [Source:ZFIN;Acc:ZDB-GENE-030826-21])

HSP 1 Score: 180.644 bits (457), Expect = 3.826e-58
Identity = 91/162 (56.17%), Postives = 126/162 (77.78%), Query Frame = 2 
Query:   47 TMNSKKKVDKMTIELSEKQKEDIQKAFNLFDKDGSGTIDIQEVKVALRALDFEPLKDDIRKLISEYDKDNKGTIDFNNFLILISSKMTEPDSKEDITKAFNLFDKDGKEKISIHNLKSISEILGENLTDEELQEMLFNADRDNPGEVNERDFHRIMKKNSFY 532
            + N +KK      EL+E+QK++I++AF+LFD DGSGTID++E+KVA+RAL FEP K++I+K+I++ DK+  G I F++FL +++ KM+E DSKE+I KAF LFD D   KIS  NLK +++ LGENLTDEELQEM+  ADRD  GE+NE++F RIMKK + Y
Sbjct:   11 SANQRKKAGPKP-ELTEEQKQEIKEAFDLFDTDGSGTIDVKELKVAMRALGFEPKKEEIKKMIADIDKEGSGVIGFSDFLSMMTQKMSEKDSKEEILKAFRLFDDDCTGKISFKNLKRVAKELGENLTDEELQEMIDEADRDGDGEINEQEFLRIMKKTNLY 171
[Close]
BLAST of Centrin vs. Ensembl Zebrafish
Match: cetn2 (centrin, EF-hand protein, 2 [Source:ZFIN;Acc:ZDB-GENE-091118-94])

HSP 1 Score: 177.948 bits (450), Expect = 5.083e-57
Identity = 88/149 (59.06%), Postives = 117/149 (78.52%), Query Frame = 2 
Query:   86 ELSEKQKEDIQKAFNLFDKDGSGTIDIQEVKVALRALDFEPLKDDIRKLISEYDKDNKGTIDFNNFLILISSKMTEPDSKEDITKAFNLFDKDGKEKISIHNLKSISEILGENLTDEELQEMLFNADRDNPGEVNERDFHRIMKKNSFY 532
            EL+E+QK++I++AF LFD DGSG I+++E+KVA+RAL FEP K++I+K+I+E DK+  G I F +FL +++ KM E DSKE+I KAF LFD D   KIS  NLK +++ LGENLTDEELQEM+  ADRD  GEVN+++F RIMKK S Y
Sbjct:   24 ELTEEQKQEIREAFELFDTDGSGYIEVKELKVAMRALGFEPKKEEIKKMIAEVDKEATGKISFTDFLSVMTQKMAEKDSKEEILKAFRLFDDDETGKISFRNLKRVAKELGENLTDEELQEMIDEADRDGDGEVNQQEFLRIMKKTSLY 172
[Close]
BLAST of Centrin vs. Ensembl Zebrafish
Match: calm3a (calmodulin 3a (phosphorylase kinase, delta) [Source:ZFIN;Acc:ZDB-GENE-030131-5590])

HSP 1 Score: 124.02 bits (310), Expect = 3.144e-36
Identity = 64/146 (43.84%), Postives = 97/146 (66.44%), Query Frame = 2 
Query:   77 MTIELSEKQKEDIQKAFNLFDKDGSGTIDIQEVKVALRALDFEPLKDDIRKLISEYDKDNKGTIDFNNFLILISSKMTEPDSKEDITKAFNLFDKDGKEKISIHNLKSISEILGENLTDEELQEMLFNADRDNPGEVNERDFHRIM 514
            M  +L+E+Q  + ++AF+LFDKDG GTI  +E+   +R+L   P + +++ +I+E D D  GTIDF  FL +++ KM + DS+E+I +AF +FDKDG   IS   L+ +   LGE LTDEE+ EM+  AD D  G+VN  +F ++M
Sbjct:    1 MADQLTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVQMM 146

HSP 2 Score: 46.2098 bits (108), Expect = 2.471e-6
Identity = 23/61 (37.70%), Postives = 37/61 (60.66%), Query Frame = 2 
Query:  338 KAFNLFDKDGKEKISIHNLKSISEILGENLTDEELQEMLFNADRDNPGEVNERDFHRIMKK 520
            +AF+LFDKDG   I+   L ++   LG+N T+ ELQ+M+   D D  G ++  +F  +M +
Sbjct:   15 EAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPEFLTMMAR 75
[Close]
BLAST of Centrin vs. Ensembl Zebrafish
Match: calm3b (calmodulin 3b (phosphorylase kinase, delta) [Source:ZFIN;Acc:ZDB-GENE-030131-527])

HSP 1 Score: 124.02 bits (310), Expect = 3.144e-36
Identity = 64/146 (43.84%), Postives = 97/146 (66.44%), Query Frame = 2 
Query:   77 MTIELSEKQKEDIQKAFNLFDKDGSGTIDIQEVKVALRALDFEPLKDDIRKLISEYDKDNKGTIDFNNFLILISSKMTEPDSKEDITKAFNLFDKDGKEKISIHNLKSISEILGENLTDEELQEMLFNADRDNPGEVNERDFHRIM 514
            M  +L+E+Q  + ++AF+LFDKDG GTI  +E+   +R+L   P + +++ +I+E D D  GTIDF  FL +++ KM + DS+E+I +AF +FDKDG   IS   L+ +   LGE LTDEE+ EM+  AD D  G+VN  +F ++M
Sbjct:    1 MADQLTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVQMM 146

HSP 2 Score: 46.2098 bits (108), Expect = 2.471e-6
Identity = 23/61 (37.70%), Postives = 37/61 (60.66%), Query Frame = 2 
Query:  338 KAFNLFDKDGKEKISIHNLKSISEILGENLTDEELQEMLFNADRDNPGEVNERDFHRIMKK 520
            +AF+LFDKDG   I+   L ++   LG+N T+ ELQ+M+   D D  G ++  +F  +M +
Sbjct:   15 EAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPEFLTMMAR 75
[Close]
BLAST of Centrin vs. Ensembl Zebrafish
Match: calm1b (calmodulin 1b [Source:ZFIN;Acc:ZDB-GENE-030804-2])

HSP 1 Score: 124.02 bits (310), Expect = 3.144e-36
Identity = 64/146 (43.84%), Postives = 97/146 (66.44%), Query Frame = 2 
Query:   77 MTIELSEKQKEDIQKAFNLFDKDGSGTIDIQEVKVALRALDFEPLKDDIRKLISEYDKDNKGTIDFNNFLILISSKMTEPDSKEDITKAFNLFDKDGKEKISIHNLKSISEILGENLTDEELQEMLFNADRDNPGEVNERDFHRIM 514
            M  +L+E+Q  + ++AF+LFDKDG GTI  +E+   +R+L   P + +++ +I+E D D  GTIDF  FL +++ KM + DS+E+I +AF +FDKDG   IS   L+ +   LGE LTDEE+ EM+  AD D  G+VN  +F ++M
Sbjct:    1 MADQLTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVQMM 146

HSP 2 Score: 46.2098 bits (108), Expect = 2.471e-6
Identity = 23/61 (37.70%), Postives = 37/61 (60.66%), Query Frame = 2 
Query:  338 KAFNLFDKDGKEKISIHNLKSISEILGENLTDEELQEMLFNADRDNPGEVNERDFHRIMKK 520
            +AF+LFDKDG   I+   L ++   LG+N T+ ELQ+M+   D D  G ++  +F  +M +
Sbjct:   15 EAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPEFLTMMAR 75
[Close]
BLAST of Centrin vs. Ensembl Xenopus
Match: dtl (denticleless E3 ubiquitin protein ligase homolog [Source:Xenbase;Acc:XB-GENE-985623])

HSP 1 Score: 181.415 bits (459), Expect = 2.351e-58
Identity = 90/149 (60.40%), Postives = 120/149 (80.54%), Query Frame = 2 
Query:   86 ELSEKQKEDIQKAFNLFDKDGSGTIDIQEVKVALRALDFEPLKDDIRKLISEYDKDNKGTIDFNNFLILISSKMTEPDSKEDITKAFNLFDKDGKEKISIHNLKSISEILGENLTDEELQEMLFNADRDNPGEVNERDFHRIMKKNSFY 532
            EL+E+QK++I++AF+LFD DGSGTID++E+KVA+RAL FEP K++++K+IS+ DKD  G IDF +FL L++ KM+E DSKE+I KAF LFD D   KIS  NLK +++ LGENLTDEELQEM+  ADRD  GE+NE++F RIM+K S  
Sbjct:   23 ELTEEQKQEIREAFDLFDTDGSGTIDVKELKVAMRALGFEPKKEEMKKIISDTDKDGSGIIDFEDFLSLMTQKMSEKDSKEEIMKAFRLFDDDNTGKISFKNLKRVAKELGENLTDEELQEMIDEADRDGDGEINEQEFLRIMRKTSLC 171
[Close]
BLAST of Centrin vs. Ensembl Xenopus
Match: dtl (denticleless E3 ubiquitin protein ligase homolog [Source:Xenbase;Acc:XB-GENE-985623])

HSP 1 Score: 180.644 bits (457), Expect = 6.345e-58
Identity = 90/149 (60.40%), Postives = 120/149 (80.54%), Query Frame = 2 
Query:   86 ELSEKQKEDIQKAFNLFDKDGSGTIDIQEVKVALRALDFEPLKDDIRKLISEYDKDNKGTIDFNNFLILISSKMTEPDSKEDITKAFNLFDKDGKEKISIHNLKSISEILGENLTDEELQEMLFNADRDNPGEVNERDFHRIMKKNSFY 532
            EL+E+QK++I++AF+LFD DGSGTID++E+KVA+RAL FEP K++++K+IS+ DKD  G IDF +FL L++ KM+E DSKE+I KAF LFD D   KIS  NLK +++ LGENLTDEELQEM+  ADRD  GE+NE++F RIM+K S  
Sbjct:   24 ELTEEQKQEIREAFDLFDTDGSGTIDVKELKVAMRALGFEPKKEEMKKIISDTDKDGSGIIDFEDFLSLMTQKMSEKDSKEEIMKAFRLFDDDNTGKISFKNLKRVAKELGENLTDEELQEMIDEADRDGDGEINEQEFLRIMRKTSLC 172
[Close]
BLAST of Centrin vs. Ensembl Xenopus
Match: cetn1 (centrin 1 [Source:NCBI gene;Acc:549903])

HSP 1 Score: 179.489 bits (454), Expect = 1.319e-57
Identity = 93/162 (57.41%), Postives = 123/162 (75.93%), Query Frame = 2 
Query:   47 TMNSKKKVDKMTIELSEKQKEDIQKAFNLFDKDGSGTIDIQEVKVALRALDFEPLKDDIRKLISEYDKDNKGTIDFNNFLILISSKMTEPDSKEDITKAFNLFDKDGKEKISIHNLKSISEILGENLTDEELQEMLFNADRDNPGEVNERDFHRIMKKNSFY 532
            T   KK V K   EL+E+QK++I++AF+LFD DG+GTID++E+KVA+RAL FEP K++I+K+I++ DK+  G I F +F+  ++ KM E DSKE+I KAF LFD D   KIS  NLK +++ LGENLTDEELQEM+  ADRD  GEVNE++F RIMKK S Y
Sbjct:   13 TTQRKKPVPK--PELTEEQKQEIREAFDLFDTDGAGTIDVKELKVAMRALGFEPKKEEIKKMIADIDKEGTGKISFGDFMSAMTQKMAEKDSKEEIMKAFRLFDDDETGKISFKNLKRVAKELGENLTDEELQEMIDEADRDGDGEVNEQEFLRIMKKTSLY 172
[Close]
BLAST of Centrin vs. Ensembl Xenopus
Match: cetn1 (centrin 1 [Source:NCBI gene;Acc:549903])

HSP 1 Score: 177.948 bits (450), Expect = 3.426e-57
Identity = 88/149 (59.06%), Postives = 118/149 (79.19%), Query Frame = 2 
Query:   86 ELSEKQKEDIQKAFNLFDKDGSGTIDIQEVKVALRALDFEPLKDDIRKLISEYDKDNKGTIDFNNFLILISSKMTEPDSKEDITKAFNLFDKDGKEKISIHNLKSISEILGENLTDEELQEMLFNADRDNPGEVNERDFHRIMKKNSFY 532
            EL+E+QK++I++AF+LFD DG+GTID++E+KVA+RAL FEP K++I+K+I++ DK+  G I F +F+  ++ KM E DSKE+I KAF LFD D   KIS  NLK +++ LGENLTDEELQEM+  ADRD  GEVNE++F RIMKK S Y
Sbjct:    9 ELTEEQKQEIREAFDLFDTDGAGTIDVKELKVAMRALGFEPKKEEIKKMIADIDKEGTGKISFGDFMSAMTQKMAEKDSKEEIMKAFRLFDDDETGKISFKNLKRVAKELGENLTDEELQEMIDEADRDGDGEVNEQEFLRIMKKTSLY 157
[Close]
BLAST of Centrin vs. Ensembl Xenopus
Match: CALM2 (calmodulin 1 (phosphorylase kinase, delta) [Source:NCBI gene;Acc:100496298])

HSP 1 Score: 124.02 bits (310), Expect = 4.479e-36
Identity = 64/146 (43.84%), Postives = 97/146 (66.44%), Query Frame = 2 
Query:   77 MTIELSEKQKEDIQKAFNLFDKDGSGTIDIQEVKVALRALDFEPLKDDIRKLISEYDKDNKGTIDFNNFLILISSKMTEPDSKEDITKAFNLFDKDGKEKISIHNLKSISEILGENLTDEELQEMLFNADRDNPGEVNERDFHRIM 514
            M  +L+E+Q  + ++AF+LFDKDG GTI  +E+   +R+L   P + +++ +I+E D D  GTIDF  FL +++ KM + DS+E+I +AF +FDKDG   IS   L+ +   LGE LTDEE+ EM+  AD D  G+VN  +F ++M
Sbjct:    1 MADQLTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVQMM 146

HSP 2 Score: 46.2098 bits (108), Expect = 3.522e-6
Identity = 23/61 (37.70%), Postives = 37/61 (60.66%), Query Frame = 2 
Query:  338 KAFNLFDKDGKEKISIHNLKSISEILGENLTDEELQEMLFNADRDNPGEVNERDFHRIMKK 520
            +AF+LFDKDG   I+   L ++   LG+N T+ ELQ+M+   D D  G ++  +F  +M +
Sbjct:   15 EAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPEFLTMMAR 75
[Close]
BLAST of Centrin vs. Ensembl Mouse
Match: Cetn2 (centrin 2 [Source:MGI Symbol;Acc:MGI:1347085])

HSP 1 Score: 182.956 bits (463), Expect = 5.409e-59
Identity = 94/164 (57.32%), Postives = 128/164 (78.05%), Query Frame = 2 
Query:   47 TMNSKKKVDKMTI--ELSEKQKEDIQKAFNLFDKDGSGTIDIQEVKVALRALDFEPLKDDIRKLISEYDKDNKGTIDFNNFLILISSKMTEPDSKEDITKAFNLFDKDGKEKISIHNLKSISEILGENLTDEELQEMLFNADRDNPGEVNERDFHRIMKKNSFY 532
            TM S  +  +M+   EL+E QK++I++AF+LFD DG+GTIDI+E+KVA+RAL FEP K++I+K+ISE DK+  G ++F++FL +++ KM+E D+KE+I KAF LFD D   KIS  NLK +++ LGENLTDEELQEM+  ADRD  GEVNE++F RIMKK S Y
Sbjct:    9 TMASSAQRKRMSPKPELTEDQKQEIREAFDLFDADGTGTIDIKELKVAMRALGFEPKKEEIKKMISEIDKEGTGKMNFSDFLTVMTQKMSEKDTKEEILKAFKLFDDDETGKISFKNLKRVAKELGENLTDEELQEMIDEADRDGDGEVNEQEFLRIMKKTSLY 172
[Close]
BLAST of Centrin vs. Ensembl Mouse
Match: Cetn2 (centrin 2 [Source:MGI Symbol;Acc:MGI:1347085])

HSP 1 Score: 181.8 bits (460), Expect = 1.224e-58
Identity = 90/149 (60.40%), Postives = 121/149 (81.21%), Query Frame = 2 
Query:   86 ELSEKQKEDIQKAFNLFDKDGSGTIDIQEVKVALRALDFEPLKDDIRKLISEYDKDNKGTIDFNNFLILISSKMTEPDSKEDITKAFNLFDKDGKEKISIHNLKSISEILGENLTDEELQEMLFNADRDNPGEVNERDFHRIMKKNSFY 532
            EL+E QK++I++AF+LFD DG+GTIDI+E+KVA+RAL FEP K++I+K+ISE DK+  G ++F++FL +++ KM+E D+KE+I KAF LFD D   KIS  NLK +++ LGENLTDEELQEM+  ADRD  GEVNE++F RIMKK S Y
Sbjct:   15 ELTEDQKQEIREAFDLFDADGTGTIDIKELKVAMRALGFEPKKEEIKKMISEIDKEGTGKMNFSDFLTVMTQKMSEKDTKEEILKAFKLFDDDETGKISFKNLKRVAKELGENLTDEELQEMIDEADRDGDGEVNEQEFLRIMKKTSLY 163
[Close]
BLAST of Centrin vs. Ensembl Mouse
Match: Cetn2 (centrin 2 [Source:MGI Symbol;Acc:MGI:1347085])

HSP 1 Score: 181.8 bits (460), Expect = 1.224e-58
Identity = 90/149 (60.40%), Postives = 121/149 (81.21%), Query Frame = 2 
Query:   86 ELSEKQKEDIQKAFNLFDKDGSGTIDIQEVKVALRALDFEPLKDDIRKLISEYDKDNKGTIDFNNFLILISSKMTEPDSKEDITKAFNLFDKDGKEKISIHNLKSISEILGENLTDEELQEMLFNADRDNPGEVNERDFHRIMKKNSFY 532
            EL+E QK++I++AF+LFD DG+GTIDI+E+KVA+RAL FEP K++I+K+ISE DK+  G ++F++FL +++ KM+E D+KE+I KAF LFD D   KIS  NLK +++ LGENLTDEELQEM+  ADRD  GEVNE++F RIMKK S Y
Sbjct:   15 ELTEDQKQEIREAFDLFDADGTGTIDIKELKVAMRALGFEPKKEEIKKMISEIDKEGTGKMNFSDFLTVMTQKMSEKDTKEEILKAFKLFDDDETGKISFKNLKRVAKELGENLTDEELQEMIDEADRDGDGEVNEQEFLRIMKKTSLY 163
[Close]
BLAST of Centrin vs. Ensembl Mouse
Match: Cetn1 (centrin 1 [Source:MGI Symbol;Acc:MGI:1347086])

HSP 1 Score: 176.407 bits (446), Expect = 1.803e-56
Identity = 87/149 (58.39%), Postives = 117/149 (78.52%), Query Frame = 2 
Query:   86 ELSEKQKEDIQKAFNLFDKDGSGTIDIQEVKVALRALDFEPLKDDIRKLISEYDKDNKGTIDFNNFLILISSKMTEPDSKEDITKAFNLFDKDGKEKISIHNLKSISEILGENLTDEELQEMLFNADRDNPGEVNERDFHRIMKKNSFY 532
            EL+E QK+++++AF+LFD DGSGTID++E+KVA+RAL FEP K++++K+ISE DK+  G I FN+FL +++ KM E D+KE+I KAF LFD D   KIS  NLK ++  LGE+LTDEELQEM+  ADRD  GEVNE +F +IMKK + Y
Sbjct:   24 ELTEDQKQEVREAFDLFDSDGSGTIDVKELKVAMRALGFEPRKEEMKKMISEVDKEATGKISFNDFLAVMTQKMAEKDTKEEILKAFRLFDDDETGKISFKNLKRVANELGESLTDEELQEMIDEADRDGDGEVNEEEFLKIMKKTNLY 172
[Close]
BLAST of Centrin vs. Ensembl Mouse
Match: Cetn1 (centrin 1 [Source:MGI Symbol;Acc:MGI:1347086])

HSP 1 Score: 176.407 bits (446), Expect = 1.803e-56
Identity = 87/149 (58.39%), Postives = 117/149 (78.52%), Query Frame = 2 
Query:   86 ELSEKQKEDIQKAFNLFDKDGSGTIDIQEVKVALRALDFEPLKDDIRKLISEYDKDNKGTIDFNNFLILISSKMTEPDSKEDITKAFNLFDKDGKEKISIHNLKSISEILGENLTDEELQEMLFNADRDNPGEVNERDFHRIMKKNSFY 532
            EL+E QK+++++AF+LFD DGSGTID++E+KVA+RAL FEP K++++K+ISE DK+  G I FN+FL +++ KM E D+KE+I KAF LFD D   KIS  NLK ++  LGE+LTDEELQEM+  ADRD  GEVNE +F +IMKK + Y
Sbjct:   24 ELTEDQKQEVREAFDLFDSDGSGTIDVKELKVAMRALGFEPRKEEMKKMISEVDKEATGKISFNDFLAVMTQKMAEKDTKEEILKAFRLFDDDETGKISFKNLKRVANELGESLTDEELQEMIDEADRDGDGEVNEEEFLKIMKKTNLY 172
[Close]
BLAST of Centrin vs. UniProt/SwissProt
Match: sp|Q9R1K9|CETN2_MOUSE (Centrin-2 OS=Mus musculus OX=10090 GN=Cetn2 PE=1 SV=1)

HSP 1 Score: 182.956 bits (463), Expect = 3.784e-58
Identity = 94/164 (57.32%), Postives = 128/164 (78.05%), Query Frame = 2 
Query:   47 TMNSKKKVDKMTI--ELSEKQKEDIQKAFNLFDKDGSGTIDIQEVKVALRALDFEPLKDDIRKLISEYDKDNKGTIDFNNFLILISSKMTEPDSKEDITKAFNLFDKDGKEKISIHNLKSISEILGENLTDEELQEMLFNADRDNPGEVNERDFHRIMKKNSFY 532
            TM S  +  +M+   EL+E QK++I++AF+LFD DG+GTIDI+E+KVA+RAL FEP K++I+K+ISE DK+  G ++F++FL +++ KM+E D+KE+I KAF LFD D   KIS  NLK +++ LGENLTDEELQEM+  ADRD  GEVNE++F RIMKK S Y
Sbjct:    9 TMASSAQRKRMSPKPELTEDQKQEIREAFDLFDADGTGTIDIKELKVAMRALGFEPKKEEIKKMISEIDKEGTGKMNFSDFLTVMTQKMSEKDTKEEILKAFKLFDDDETGKISFKNLKRVAKELGENLTDEELQEMIDEADRDGDGEVNEQEFLRIMKKTSLY 172
[Close]
BLAST of Centrin vs. UniProt/SwissProt
Match: sp|P43646|CATR_TETST (Caltractin (Fragment) OS=Tetraselmis striata OX=3165 PE=2 SV=1)

HSP 1 Score: 181.8 bits (460), Expect = 4.805e-58
Identity = 90/148 (60.81%), Postives = 118/148 (79.73%), Query Frame = 2 
Query:   89 LSEKQKEDIQKAFNLFDKDGSGTIDIQEVKVALRALDFEPLKDDIRKLISEYDKDNKGTIDFNNFLILISSKMTEPDSKEDITKAFNLFDKDGKEKISIHNLKSISEILGENLTDEELQEMLFNADRDNPGEVNERDFHRIMKKNSFY 532
            L+E+QK+DI++AF+LFD DGSGTID +E+KVA+RAL FEP K++I+K+I++ DKD  GTIDF  FL ++++KM E DS+E+I KAF LFD D   KIS  NLK +++ LGEN+TDEELQEM+  ADRD  GEVNE +F RIMKK S +
Sbjct:    1 LTEEQKQDIREAFDLFDTDGSGTIDAKELKVAMRALGFEPKKEEIKKMIADIDKDGSGTIDFEEFLQMMTAKMGERDSREEIMKAFRLFDDDETGKISFKNLKRVAKELGENMTDEELQEMIDEADRDGDGEVNEEEFFRIMKKTSLF 148
[Close]
BLAST of Centrin vs. UniProt/SwissProt
Match: sp|Q06827|CATR_SCHDU (Caltractin OS=Scherffelia dubia OX=3190 PE=1 SV=1)

HSP 1 Score: 181.03 bits (458), Expect = 1.571e-57
Identity = 89/148 (60.14%), Postives = 118/148 (79.73%), Query Frame = 2 
Query:   89 LSEKQKEDIQKAFNLFDKDGSGTIDIQEVKVALRALDFEPLKDDIRKLISEYDKDNKGTIDFNNFLILISSKMTEPDSKEDITKAFNLFDKDGKEKISIHNLKSISEILGENLTDEELQEMLFNADRDNPGEVNERDFHRIMKKNSFY 532
            L+E+QK++I++AF+LFD DGSGTID +E+KVA+RAL FEP K++I+K+I++ DKD  GTIDF  FL ++++KM E DS+E+I KAF LFD D   KIS  NLK +++ LGEN+TDEELQEM+  ADRD  GEVNE +F RIMKK S +
Sbjct:   21 LTEEQKQEIREAFDLFDTDGSGTIDAKELKVAMRALGFEPKKEEIKKMIADIDKDGSGTIDFEEFLQMMTAKMGERDSREEIMKAFRLFDDDETGKISFKNLKRVAKELGENMTDEELQEMIDEADRDGDGEVNEEEFFRIMKKTSLF 168
[Close]
BLAST of Centrin vs. UniProt/SwissProt
Match: sp|Q2TBN3|CETN2_BOVIN (Centrin-2 OS=Bos taurus OX=9913 GN=CETN2 PE=2 SV=1)

HSP 1 Score: 180.644 bits (457), Expect = 2.476e-57
Identity = 88/149 (59.06%), Postives = 122/149 (81.88%), Query Frame = 2 
Query:   86 ELSEKQKEDIQKAFNLFDKDGSGTIDIQEVKVALRALDFEPLKDDIRKLISEYDKDNKGTIDFNNFLILISSKMTEPDSKEDITKAFNLFDKDGKEKISIHNLKSISEILGENLTDEELQEMLFNADRDNPGEVNERDFHRIMKKNSFY 532
            EL+E+QK++I++AF+LFD DG+GTID++E+KVA+RAL FEP K++I+K+ISE DK+  G ++F++FL +++ KM+E D+KE+I KAF LFD D   KIS  NLK +++ LGENL+DEELQEM+  ADRD  GEVNE++F RIMKK S Y
Sbjct:   24 ELTEEQKQEIREAFDLFDADGTGTIDVKELKVAMRALGFEPKKEEIKKMISEIDKEGTGKMNFSDFLTVMTQKMSEKDTKEEILKAFKLFDDDETGKISFKNLKRVAKELGENLSDEELQEMIDEADRDGDGEVNEQEFLRIMKKTSLY 172
[Close]
BLAST of Centrin vs. UniProt/SwissProt
Match: sp|P41208|CETN2_HUMAN (Centrin-2 OS=Homo sapiens OX=9606 GN=CETN2 PE=1 SV=1)

HSP 1 Score: 180.259 bits (456), Expect = 3.709e-57
Identity = 88/149 (59.06%), Postives = 121/149 (81.21%), Query Frame = 2 
Query:   86 ELSEKQKEDIQKAFNLFDKDGSGTIDIQEVKVALRALDFEPLKDDIRKLISEYDKDNKGTIDFNNFLILISSKMTEPDSKEDITKAFNLFDKDGKEKISIHNLKSISEILGENLTDEELQEMLFNADRDNPGEVNERDFHRIMKKNSFY 532
            EL+E+QK++I++AF+LFD DG+GTID++E+KVA+RAL FEP K++I+K+ISE DK+  G ++F +FL +++ KM+E D+KE+I KAF LFD D   KIS  NLK +++ LGENLTDEELQEM+  ADRD  GEV+E++F RIMKK S Y
Sbjct:   24 ELTEEQKQEIREAFDLFDADGTGTIDVKELKVAMRALGFEPKKEEIKKMISEIDKEGTGKMNFGDFLTVMTQKMSEKDTKEEILKAFKLFDDDETGKISFKNLKRVAKELGENLTDEELQEMIDEADRDGDGEVSEQEFLRIMKKTSLY 172
[Close]
BLAST of Centrin vs. TrEMBL
Match: A0A1I8IGH5 (Uncharacterized protein OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig027230g2 PE=4 SV=1)

HSP 1 Score: 199.519 bits (506), Expect = 2.544e-62
Identity = 101/160 (63.12%), Postives = 130/160 (81.25%), Query Frame = 2 
Query:   53 NSKKKVDKMTIELSEKQKEDIQKAFNLFDKDGSGTIDIQEVKVALRALDFEPLKDDIRKLISEYDKDNKGTIDFNNFLILISSKMTEPDSKEDITKAFNLFDKDGKEKISIHNLKSISEILGENLTDEELQEMLFNADRDNPGEVNERDFHRIMKKNSFY 532
              KKK   + +ELSE+QK++I++AF+LF+ DGSGTIDI+E+KVA+RAL FEP K++I+KLI+EYDK+  GTIDFN+FL +++SKMTE DSKE+I KAF LFD D  +KIS  NLK +++ LGENLTDEELQEM+  ADRD  GE+NE +F RIMKK S Y
Sbjct:   11 GQKKKTAGIKLELSEEQKQEIREAFDLFNNDGSGTIDIKELKVAMRALGFEPKKEEIKKLIAEYDKEGTGTIDFNDFLSMMTSKMTEKDSKEEILKAFRLFDDDETDKISFKNLKRVAKELGENLTDEELQEMIDEADRDGDGEINESEFLRIMKKTSLY 170
[Close]
BLAST of Centrin vs. TrEMBL
Match: A0A267EVD4 (Uncharacterized protein (Fragment) OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig027230g1 PE=4 SV=1)

HSP 1 Score: 199.519 bits (506), Expect = 2.750e-62
Identity = 101/158 (63.92%), Postives = 129/158 (81.65%), Query Frame = 2 
Query:   59 KKKVDKMTIELSEKQKEDIQKAFNLFDKDGSGTIDIQEVKVALRALDFEPLKDDIRKLISEYDKDNKGTIDFNNFLILISSKMTEPDSKEDITKAFNLFDKDGKEKISIHNLKSISEILGENLTDEELQEMLFNADRDNPGEVNERDFHRIMKKNSFY 532
            KKK   + +ELSE+QK++I++AF+LF+ DGSGTIDI+E+KVA+RAL FEP K++I+KLI+EYDK+  GTIDFN+FL +++SKMTE DSKE+I KAF LFD D   KIS  NLK +++ LGENLTDEELQEM+  ADRD  GE+NE +F RIMKK S Y
Sbjct:    9 KKKTAGIKLELSEEQKQEIREAFDLFNNDGSGTIDIKELKVAMRALGFEPKKEEIKKLIAEYDKEGTGTIDFNDFLSMMTSKMTEKDSKEEILKAFRLFDDDETGKISFKNLKRVAKELGENLTDEELQEMIDEADRDGDGEINESEFLRIMKKTSLY 166
[Close]
BLAST of Centrin vs. TrEMBL
Match: A0A267ED52 (Uncharacterized protein (Fragment) OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig000482g1 PE=4 SV=1)

HSP 1 Score: 199.519 bits (506), Expect = 3.344e-62
Identity = 101/160 (63.12%), Postives = 129/160 (80.62%), Query Frame = 2 
Query:   53 NSKKKVDKMTIELSEKQKEDIQKAFNLFDKDGSGTIDIQEVKVALRALDFEPLKDDIRKLISEYDKDNKGTIDFNNFLILISSKMTEPDSKEDITKAFNLFDKDGKEKISIHNLKSISEILGENLTDEELQEMLFNADRDNPGEVNERDFHRIMKKNSFY 532
              KKK   + +ELSE+QK++I++AF+LF+ DGSGTIDI+E+KVA+RAL FEP K++I+KLI+EYDKD  G+IDFN+FL +++SKMTE DSKE+I KAF LFD D   KIS  NLK +++ LGENLTDEELQEM+  ADRD  GE+NE +F RIMKK S Y
Sbjct:   11 GQKKKAAGIKLELSEEQKQEIREAFDLFNNDGSGTIDIKELKVAMRALGFEPKKEEIKKLIAEYDKDGTGSIDFNDFLSMMTSKMTEKDSKEEILKAFRLFDDDETGKISFKNLKRVAKELGENLTDEELQEMIDEADRDGDGEINESEFLRIMKKTSLY 170
[Close]
BLAST of Centrin vs. TrEMBL
Match: A0A1I8II50 (Uncharacterized protein OS=Macrostomum lignano OX=282301 PE=4 SV=1)

HSP 1 Score: 199.134 bits (505), Expect = 4.492e-62
Identity = 101/160 (63.12%), Postives = 129/160 (80.62%), Query Frame = 2 
Query:   53 NSKKKVDKMTIELSEKQKEDIQKAFNLFDKDGSGTIDIQEVKVALRALDFEPLKDDIRKLISEYDKDNKGTIDFNNFLILISSKMTEPDSKEDITKAFNLFDKDGKEKISIHNLKSISEILGENLTDEELQEMLFNADRDNPGEVNERDFHRIMKKNSFY 532
              KKK   + +ELSE+QK++I++AF+LF+ DGSGTIDI+E+KVA+RAL FEP K++I+KLI+EYDK+  GTIDFN+FL +++SKMTE DSKE+I KAF LFD D   KIS  NLK +++ LGENLTDEELQEM+  ADRD  GE+NE +F RIMKK S Y
Sbjct:   11 GQKKKTAGIKLELSEEQKQEIREAFDLFNNDGSGTIDIKELKVAMRALGFEPKKEEIKKLIAEYDKEGTGTIDFNDFLSMMTSKMTEKDSKEEILKAFRLFDDDETGKISFKNLKRVAKELGENLTDEELQEMIDEADRDGDGEINESEFLRIMKKTSLY 170
[Close]
BLAST of Centrin vs. TrEMBL
Match: A0A1S3GYU6 (caltractin OS=Lingula unguis OX=7574 GN=LOC106150522 PE=4 SV=1)

HSP 1 Score: 196.052 bits (497), Expect = 6.990e-61
Identity = 98/162 (60.49%), Postives = 128/162 (79.01%), Query Frame = 2 
Query:   47 TMNSKKKVDKMTIELSEKQKEDIQKAFNLFDKDGSGTIDIQEVKVALRALDFEPLKDDIRKLISEYDKDNKGTIDFNNFLILISSKMTEPDSKEDITKAFNLFDKDGKEKISIHNLKSISEILGENLTDEELQEMLFNADRDNPGEVNERDFHRIMKKNSFY 532
            T+   +K      EL+E+QK++I++AF+LFD DGSGTID +E+KVA+RAL FEP K++I+K+IS+ DKD  GTIDFN+FL L++ KM+E DSKE+I KAF LFD+DG  KIS  NLK +++ LGENLTDEELQEM+  ADRD  GE+NE++F RIMKK S Y
Sbjct:    8 TVGGNRKKGGPKAELTEEQKQEIREAFDLFDTDGSGTIDAKELKVAMRALGFEPKKEEIKKMISDIDKDGSGTIDFNDFLTLMTQKMSEKDSKEEILKAFRLFDEDGTGKISFKNLKRVAKELGENLTDEELQEMIDEADRDGDGEINEQEFLRIMKKTSLY 169
[Close]
BLAST of Centrin vs. Ensembl Cavefish
Match: cetn4 (caltractin [Source:NCBI gene;Acc:103037928])

HSP 1 Score: 187.963 bits (476), Expect = 4.227e-61
Identity = 94/162 (58.02%), Postives = 130/162 (80.25%), Query Frame = 2 
Query:   47 TMNSKKKVDKMTIELSEKQKEDIQKAFNLFDKDGSGTIDIQEVKVALRALDFEPLKDDIRKLISEYDKDNKGTIDFNNFLILISSKMTEPDSKEDITKAFNLFDKDGKEKISIHNLKSISEILGENLTDEELQEMLFNADRDNPGEVNERDFHRIMKKNSFY 532
            T N +KK     ++L+E+QK++I++AF+LFD DGSGTID++E+KVA+RAL FEP K++I+K+I++ DK+  GTI+FN+FL +++ KM+E DSKE+I KAF LFD DG  KIS  NLK +++ LGENLTDEELQEM+  ADRD  GE+NE++F RIMKK + Y
Sbjct:   12 TANQRKKGGP-KVDLTEEQKQEIREAFDLFDTDGSGTIDVKELKVAMRALGFEPKKEEIKKMIADIDKEGSGTINFNDFLSMMTQKMSEKDSKEEILKAFRLFDDDGTGKISFKNLKRVAKELGENLTDEELQEMIDEADRDGDGEINEQEFLRIMKKTNLY 172
[Close]
BLAST of Centrin vs. Ensembl Cavefish
Match: cetn4 (caltractin [Source:NCBI gene;Acc:103037928])

HSP 1 Score: 187.963 bits (476), Expect = 4.468e-61
Identity = 94/162 (58.02%), Postives = 130/162 (80.25%), Query Frame = 2 
Query:   47 TMNSKKKVDKMTIELSEKQKEDIQKAFNLFDKDGSGTIDIQEVKVALRALDFEPLKDDIRKLISEYDKDNKGTIDFNNFLILISSKMTEPDSKEDITKAFNLFDKDGKEKISIHNLKSISEILGENLTDEELQEMLFNADRDNPGEVNERDFHRIMKKNSFY 532
            T N +KK     ++L+E+QK++I++AF+LFD DGSGTID++E+KVA+RAL FEP K++I+K+I++ DK+  GTI+FN+FL +++ KM+E DSKE+I KAF LFD DG  KIS  NLK +++ LGENLTDEELQEM+  ADRD  GE+NE++F RIMKK + Y
Sbjct:   11 TANQRKKGGP-KVDLTEEQKQEIREAFDLFDTDGSGTIDVKELKVAMRALGFEPKKEEIKKMIADIDKEGSGTINFNDFLSMMTQKMSEKDSKEEILKAFRLFDDDGTGKISFKNLKRVAKELGENLTDEELQEMIDEADRDGDGEINEQEFLRIMKKTNLY 171
[Close]
BLAST of Centrin vs. Ensembl Cavefish
Match: cetn2 (centrin-1 [Source:NCBI gene;Acc:103028142])

HSP 1 Score: 176.407 bits (446), Expect = 1.356e-56
Identity = 87/149 (58.39%), Postives = 116/149 (77.85%), Query Frame = 2 
Query:   86 ELSEKQKEDIQKAFNLFDKDGSGTIDIQEVKVALRALDFEPLKDDIRKLISEYDKDNKGTIDFNNFLILISSKMTEPDSKEDITKAFNLFDKDGKEKISIHNLKSISEILGENLTDEELQEMLFNADRDNPGEVNERDFHRIMKKNSFY 532
            EL+E+ K++I++AF LFD DGSG I+++E+KVA+RAL FEP K++I+K+I++ DKD  G I FN+FL +++ KM E DSKE+I KAF LFD D   KIS  NLK +++ LGENLTDEELQEM+  ADRD  GEVN+++F RIMKK   Y
Sbjct:   24 ELTEEMKQEIREAFELFDTDGSGHIEVKELKVAMRALGFEPKKEEIKKMIADVDKDGTGKISFNDFLTIMTQKMAEKDSKEEILKAFRLFDDDETGKISFRNLKRVAKELGENLTDEELQEMIDEADRDGDGEVNQQEFLRIMKKTCLY 172
[Close]
BLAST of Centrin vs. Ensembl Cavefish
Match: cetn3 (centrin 3 [Source:NCBI gene;Acc:103024517])

HSP 1 Score: 125.561 bits (314), Expect = 1.130e-36
Identity = 66/147 (44.90%), Postives = 100/147 (68.03%), Query Frame = 2 
Query:   86 ELSEKQKEDIQKAFNLFDKDGSGTIDIQEVKVALRALDFEPLKDDIRKLISEYDKDNKGTIDFNNFLILISSKMTEPDSKEDITKAFNLFDKDGKEKISIHNLKSISEILGENLTDEELQEMLFNADRDNPGEVNERDFHRIMKKNS 526
            EL+E+QK++I++AF LFD D    ID  E+KVA+RAL FE  K D+ K++ +YD++  G I F +F  +++ ++ E D KE+I KAF LFD D   KIS+ NL+ ++  LGE+++DEEL+ M+   D D  GE+N+ +F  IM  +S
Sbjct:   21 ELTEEQKDEIKEAFELFDTDKDKEIDYHELKVAMRALGFEVKKVDVLKILKDYDREGTGKITFEDFREVVTDRILERDPKEEILKAFKLFDDDESGKISLRNLRRVARELGEDMSDEELRAMIDEFDTDGDGEINQEEFVSIMTGDS 167
[Close]
BLAST of Centrin vs. Ensembl Cavefish
Match: calm3a (calmodulin [Source:NCBI gene;Acc:103037741])

HSP 1 Score: 124.02 bits (310), Expect = 2.664e-36
Identity = 64/146 (43.84%), Postives = 97/146 (66.44%), Query Frame = 2 
Query:   77 MTIELSEKQKEDIQKAFNLFDKDGSGTIDIQEVKVALRALDFEPLKDDIRKLISEYDKDNKGTIDFNNFLILISSKMTEPDSKEDITKAFNLFDKDGKEKISIHNLKSISEILGENLTDEELQEMLFNADRDNPGEVNERDFHRIM 514
            M  +L+E+Q  + ++AF+LFDKDG GTI  +E+   +R+L   P + +++ +I+E D D  GTIDF  FL +++ KM + DS+E+I +AF +FDKDG   IS   L+ +   LGE LTDEE+ EM+  AD D  G+VN  +F ++M
Sbjct:    1 MADQLTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVQMM 146

HSP 2 Score: 46.2098 bits (108), Expect = 2.094e-6
Identity = 23/61 (37.70%), Postives = 37/61 (60.66%), Query Frame = 2 
Query:  338 KAFNLFDKDGKEKISIHNLKSISEILGENLTDEELQEMLFNADRDNPGEVNERDFHRIMKK 520
            +AF+LFDKDG   I+   L ++   LG+N T+ ELQ+M+   D D  G ++  +F  +M +
Sbjct:   15 EAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPEFLTMMAR 75
[Close]
BLAST of Centrin vs. Ensembl Sea Lamprey
Match: CETN1 (centrin 1 [Source:HGNC Symbol;Acc:HGNC:1866])

HSP 1 Score: 183.726 bits (465), Expect = 5.811e-60
Identity = 89/149 (59.73%), Postives = 121/149 (81.21%), Query Frame = 2 
Query:   86 ELSEKQKEDIQKAFNLFDKDGSGTIDIQEVKVALRALDFEPLKDDIRKLISEYDKDNKGTIDFNNFLILISSKMTEPDSKEDITKAFNLFDKDGKEKISIHNLKSISEILGENLTDEELQEMLFNADRDNPGEVNERDFHRIMKKNSFY 532
            ELSE+QK++I++AF+LFD DGSGTID++E+KVA+RAL FEP K++I+K+I+++DKD  G I+FN+FL +++ KM+E DS+E+I KAF LFD D   KIS  NLK +++ LGE LTDEELQEM+  ADRD  GE+NE +F R+MKK S Y
Sbjct:   35 ELSEEQKQEIKEAFDLFDADGSGTIDVKELKVAMRALGFEPKKEEIKKMIADFDKDGSGKINFNDFLAMMTQKMSEKDSREEILKAFRLFDDDETGKISFKNLKRVAKELGETLTDEELQEMIDEADRDGDGEINEEEFLRVMKKTSLY 183
[Close]
BLAST of Centrin vs. Ensembl Sea Lamprey
Match: ENSPMAT00000006008.1 (pep scaffold:Pmarinus_7.0:GL476713:142259:146509:-1 gene:ENSPMAG00000005430.1 transcript:ENSPMAT00000006008.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 125.561 bits (314), Expect = 1.550e-37
Identity = 64/146 (43.84%), Postives = 98/146 (67.12%), Query Frame = 2 
Query:   77 MTIELSEKQKEDIQKAFNLFDKDGSGTIDIQEVKVALRALDFEPLKDDIRKLISEYDKDNKGTIDFNNFLILISSKMTEPDSKEDITKAFNLFDKDGKEKISIHNLKSISEILGENLTDEELQEMLFNADRDNPGEVNERDFHRIM 514
            M  +L+E+Q  + ++AF+LFDKDG GTI ++E+   +R+L   P + +++ +I+E D D  GTIDF  FL +++ KM + DS+E+I +AF +FDKDG   IS   L+ +   LGE LTDEE+ EM+  AD D  G+VN  +F ++M
Sbjct:    1 MADQLTEEQIAEFKEAFSLFDKDGDGTITVKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVQMM 146

HSP 2 Score: 47.3654 bits (111), Expect = 1.284e-7
Identity = 23/61 (37.70%), Postives = 38/61 (62.30%), Query Frame = 2 
Query:  338 KAFNLFDKDGKEKISIHNLKSISEILGENLTDEELQEMLFNADRDNPGEVNERDFHRIMKK 520
            +AF+LFDKDG   I++  L ++   LG+N T+ ELQ+M+   D D  G ++  +F  +M +
Sbjct:   15 EAFSLFDKDGDGTITVKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPEFLTMMAR 75

HSP 3 Score: 43.8986 bits (102), Expect = 2.567e-6
Identity = 20/67 (29.85%), Postives = 43/67 (64.18%), Query Frame = 2 
Query:  104 KEDIQKAFNLFDKDGSGTIDIQEVKVALRALDFEPLKDDIRKLISEYDKDNKGTIDFNNFLILISSK 304
            +E+I++AF +FDKDG+G I   E++  +  L  +   +++ ++I E D D  G +++  F+ ++++K
Sbjct:   83 EEEIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVQMMTAK 149
[Close]
BLAST of Centrin vs. Ensembl Sea Lamprey
Match: CALM3 (calmodulin 3 [Source:HGNC Symbol;Acc:HGNC:1449])

HSP 1 Score: 124.02 bits (310), Expect = 5.404e-37
Identity = 64/146 (43.84%), Postives = 97/146 (66.44%), Query Frame = 2 
Query:   77 MTIELSEKQKEDIQKAFNLFDKDGSGTIDIQEVKVALRALDFEPLKDDIRKLISEYDKDNKGTIDFNNFLILISSKMTEPDSKEDITKAFNLFDKDGKEKISIHNLKSISEILGENLTDEELQEMLFNADRDNPGEVNERDFHRIM 514
            M  +L+E+Q  + ++AF+LFDKDG GTI  +E+   +R+L   P + +++ +I+E D D  GTIDF  FL +++ KM + DS+E+I +AF +FDKDG   IS   L+ +   LGE LTDEE+ EM+  AD D  G+VN  +F ++M
Sbjct:    1 MADQLTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVQMM 146

HSP 2 Score: 46.2098 bits (108), Expect = 4.249e-7
Identity = 23/61 (37.70%), Postives = 37/61 (60.66%), Query Frame = 2 
Query:  338 KAFNLFDKDGKEKISIHNLKSISEILGENLTDEELQEMLFNADRDNPGEVNERDFHRIMKK 520
            +AF+LFDKDG   I+   L ++   LG+N T+ ELQ+M+   D D  G ++  +F  +M +
Sbjct:   15 EAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPEFLTMMAR 75

HSP 3 Score: 43.8986 bits (102), Expect = 2.418e-6
Identity = 20/67 (29.85%), Postives = 43/67 (64.18%), Query Frame = 2 
Query:  104 KEDIQKAFNLFDKDGSGTIDIQEVKVALRALDFEPLKDDIRKLISEYDKDNKGTIDFNNFLILISSK 304
            +E+I++AF +FDKDG+G I   E++  +  L  +   +++ ++I E D D  G +++  F+ ++++K
Sbjct:   83 EEEIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVQMMTAK 149
[Close]
BLAST of Centrin vs. Ensembl Sea Lamprey
Match: CALML3 (calmodulin like 3 [Source:HGNC Symbol;Acc:HGNC:1452])

HSP 1 Score: 123.25 bits (308), Expect = 1.059e-36
Identity = 63/143 (44.06%), Postives = 96/143 (67.13%), Query Frame = 2 
Query:   86 ELSEKQKEDIQKAFNLFDKDGSGTIDIQEVKVALRALDFEPLKDDIRKLISEYDKDNKGTIDFNNFLILISSKMTEPDSKEDITKAFNLFDKDGKEKISIHNLKSISEILGENLTDEELQEMLFNADRDNPGEVNERDFHRIM 514
            +L+E+Q  + ++AF+LFDKDG GTI  +E+   +R+L   P + +++ +I+E D D  GTIDF  FL +++ KM + DS+E+I +AF +FDKDG   IS   L+ +   LGE LTDEE+ EM+  AD D  G+VN  +F ++M
Sbjct:    4 QLTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVQMM 146

HSP 2 Score: 46.2098 bits (108), Expect = 4.335e-7
Identity = 23/61 (37.70%), Postives = 37/61 (60.66%), Query Frame = 2 
Query:  338 KAFNLFDKDGKEKISIHNLKSISEILGENLTDEELQEMLFNADRDNPGEVNERDFHRIMKK 520
            +AF+LFDKDG   I+   L ++   LG+N T+ ELQ+M+   D D  G ++  +F  +M +
Sbjct:   15 EAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPEFLTMMAR 75

HSP 3 Score: 43.8986 bits (102), Expect = 2.491e-6
Identity = 20/67 (29.85%), Postives = 43/67 (64.18%), Query Frame = 2 
Query:  104 KEDIQKAFNLFDKDGSGTIDIQEVKVALRALDFEPLKDDIRKLISEYDKDNKGTIDFNNFLILISSK 304
            +E+I++AF +FDKDG+G I   E++  +  L  +   +++ ++I E D D  G +++  F+ ++++K
Sbjct:   83 EEEIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVQMMTAK 149
[Close]
BLAST of Centrin vs. Ensembl Sea Lamprey
Match: cetn3 (centrin 3 [Source:ZFIN;Acc:ZDB-GENE-050522-152])

HSP 1 Score: 122.094 bits (305), Expect = 5.014e-36
Identity = 59/147 (40.14%), Postives = 100/147 (68.03%), Query Frame = 2 
Query:   86 ELSEKQKEDIQKAFNLFDKDGSGTIDIQEVKVALRALDFEPLKDDIRKLISEYDKDNKGTIDFNNFLILISSKMTEPDSKEDITKAFNLFDKDGKEKISIHNLKSISEILGENLTDEELQEMLFNADRDNPGEVNERDFHRIMKKNS 526
            E++E+QK++IQ+AF LFD D  G ID  E+KVA+RAL FE  K D+ K++ +YD+++ G I +++F  +++ ++ E D  +++ KAF LFD+    +I + +L+ ++  LGE ++DEEL+ M+   D D  GE+N+ +F  IM  +S
Sbjct:   22 EMTEEQKQEIQEAFELFDTDKDGAIDYHELKVAIRALGFEVSKADVIKIMKDYDREDTGKISYDDFCEVMTERVLERDPLDEVLKAFRLFDEGESGRIGVRDLRRVARELGETVSDEELRAMIDEFDTDGDGEINQEEFIAIMTGDS 168
[Close]
BLAST of Centrin vs. Ensembl Yeast
Match: CDC31 (Calcium-binding component of the spindle pole body (SPB) half-bridge; required for SPB duplication in mitosis and meiosis II; homolog of mammalian centrin; binds multiubiquitinated proteins and is involved in proteasomal protein degradation [Source:SGD;Acc:S000005783])

HSP 1 Score: 115.161 bits (287), Expect = 1.391e-33
Identity = 62/139 (44.60%), Postives = 94/139 (67.63%), Query Frame = 2 
Query:   86 ELSEKQKEDIQKAFNLFDKDGSGTIDIQEVKVALRALDFEPLKDDIRKLISEYDKDNKGTIDFNNFLILISSKMTEPDSKEDITKAFNLFDKDGKEKISIHNLKSISEILGENLTDEELQEMLFNADRDNPGEVNERDF 502
            EL E+QK++I +AF+LFD +  G +D  E+KVA++AL FE  K +I  LI EYD + +  + +++F I++  K+ + D  ++I +AF LFD D   KISI NL+ +++ LGE LTDEEL+ M+   D D  GE+NE +F
Sbjct:   16 ELLEEQKQEIYEAFSLFDMNNDGFLDYHELKVAMKALGFELPKREILDLIDEYDSEGRHLMKYDDFYIVMGEKILKRDPLDEIKRAFQLFDDDHTGKISIKNLRRVAKELGETLTDEELRAMIEEFDLDGDGEINENEF 154
[Close]
BLAST of Centrin vs. Ensembl Yeast
Match: CMD1 (Calmodulin; Ca2+ binding protein that regulates Ca2+ independent processes (mitosis, bud growth, actin organization, endocytosis, etc.) and Ca2+ dependent processes (stress-activated pathways), targets include Nuf1p, Myo2p and calcineurin; binds to the Hog1p MAPK in response to hyperosmotic stress; potentiates membrane tubulation and constriction mediated by the Rvs161p-Rvs167p complex; human CALM1 or CALM2 functionally complement repression induced inviability [Source:SGD;Acc:S000000313])

HSP 1 Score: 96.2857 bits (238), Expect = 2.188e-26
Identity = 53/148 (35.81%), Postives = 89/148 (60.14%), Query Frame = 2 
Query:   77 MTIELSEKQKEDIQKAFNLFDKDGSGTIDIQEVKVALRALDFEPLKDDIRKLISEYDKDNKGTIDFNNFLILISSKMTEPDSKEDITKAFNLFDKDGKEKISIHNLKSISEILGENLTDEELQEMLFNADRDNPGEVNERDFHRIMKK 520
            M+  L+E+Q  + ++AF LFDKD +G+I   E+   +R+L   P + ++  L++E D D    I+F+ FL L+S ++   DS++++ +AF +FDK+G   IS   LK +   +GE LTD E+ +ML     D  GE+N + F  ++ K
Sbjct:    1 MSSNLTEEQIAEFKEAFALFDKDNNGSISSSELATVMRSLGLSPSEAEVNDLMNEIDVDGNHQIEFSEFLALMSRQLKSNDSEQELLEAFKVFDKNGDGLISAAELKHVLTSIGEKLTDAEVDDMLREV-SDGSGEINIQQFAALLSK 147
[Close]
BLAST of Centrin vs. Ensembl Yeast
Match: MLC1 (Essential light chain for Myo1p; light chain for Myo2p; stabilizes Myo2p by binding to the neck region; interacts with Myo1p, Iqg1p, and Myo2p to coordinate formation and contraction of the actomyosin ring with targeted membrane deposition [Source:SGD;Acc:S000003074])

HSP 1 Score: 63.5438 bits (153), Expect = 8.266e-14
Identity = 44/132 (33.33%), Postives = 70/132 (53.03%), Query Frame = 2 
Query:  125 FNLFDKDGSGTIDIQEVKVALRALDFEPLKDDIRKLI---SEYDKDNKGTIDFNNFLILISSKMTEPDSK---EDITKAFNLFDKDGKEKISIHNLKSISEILGENLTDEELQEMLFNADRDNPGEVNERDF 502
            F LFDK G G I    +   LRA+ + P    ++ +I   S     +  T+D    LI ++ K  +  +K   ED  KAF +FDK+   K+S+ +L+ +   LGE LTD E+ E+L   + D+ GE++ + F
Sbjct:   11 FTLFDKKGQGAIAKDSLGDYLRAIGYNPTNQLVQDIINADSSLRDASSLTLDQITGLIEVNEKELDATTKAKTEDFVKAFQVFDKESTGKVSVGDLRYMLTGLGEKLTDAEVDELLKGVEVDSNGEIDYKKF 142
[Close]
BLAST of Centrin vs. Ensembl Yeast
Match: CNB1 (Calcineurin B; regulatory subunit of calcineurin, a Ca++/calmodulin-regulated type 2B protein phosphatase which regulates Crz1p (stress-response transcription factor); other calcineurin subunit encoded by CNA1 and/or CMP1; regulates function of Aly1p alpha-arrestin; myristoylation by Nmt1p reduces calcineurin activity in response to submaximal Ca signals, is needed to prevent constitutive phosphatase activity; protein abundance increases in response to DNA replication stress [Source:SGD;Acc:S000001673])

HSP 1 Score: 47.3654 bits (111), Expect = 1.365e-7
Identity = 37/117 (31.62%), Postives = 61/117 (52.14%), Query Frame = 2 
Query:  107 EDIQKAFNLFDKDGSGTIDIQEVKVALRALDFEPLKDDIRKLISEYDKDNKGTIDFNNFLILISSKMTEPDSKEDITKAFNLFDKDGKEKISIHNLKSISEIL-GENLTDEELQEML 454
            E ++K F   D+D SG+ID  E  +++  +   PL   I ++   +D DN G +DF  F+  +S         E +  AF ++D D    IS   L  + +I+ G NL DE+LQ+++
Sbjct:   24 ERLRKRFMKLDRDSSGSIDKNEF-MSIPGVSSNPLAGRIMEV---FDADNSGDVDFQEFITGLSIFSGRGSKDEKLRFAFKIYDIDKDGFISNGELFIVLKIMVGSNLDDEQLQQIV 136
[Close]
BLAST of Centrin vs. Ensembl Nematostella
Match: EDO40775 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S690])

HSP 1 Score: 187.578 bits (475), Expect = 1.521e-61
Identity = 94/149 (63.09%), Postives = 121/149 (81.21%), Query Frame = 2 
Query:   86 ELSEKQKEDIQKAFNLFDKDGSGTIDIQEVKVALRALDFEPLKDDIRKLISEYDKDNKGTIDFNNFLILISSKMTEPDSKEDITKAFNLFDKDGKEKISIHNLKSISEILGENLTDEELQEMLFNADRDNPGEVNERDFHRIMKKNSFY 532
            EL+E+QK++I++AF+LFD DGSGTID +E+KVA+RAL FEP K++I+K+IS+ DKD  GTIDFN FL ++++KM+E DSKE+I KAF LFD D   KIS  NLK +++ LGENLTDEELQEM+  ADRD  GE+NE +F RIMKK S Y
Sbjct:   14 ELTEEQKQEIREAFDLFDTDGSGTIDAKELKVAMRALGFEPKKEEIKKMISDIDKDGSGTIDFNEFLQMMTAKMSEKDSKEEILKAFKLFDDDETGKISFKNLKRVAKELGENLTDEELQEMIDEADRDGDGEINEAEFLRIMKKTSLY 162
[Close]
BLAST of Centrin vs. Ensembl Nematostella
Match: EDO44944 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RU39])

HSP 1 Score: 126.331 bits (316), Expect = 2.030e-37
Identity = 65/147 (44.22%), Postives = 102/147 (69.39%), Query Frame = 2 
Query:   86 ELSEKQKEDIQKAFNLFDKDGSGTIDIQEVKVALRALDFEPLKDDIRKLISEYDKDNKGTIDFNNFLILISSKMTEPDSKEDITKAFNLFDKDGKEKISIHNLKSISEILGENLTDEELQEMLFNADRDNPGEVNERDFHRIMKKNS 526
            EL E+Q+++I++AFNLFD D    ID  E+KVA+RAL F+  K D+ K++ +YD+++ G I F++F  +++  M + D +E++ KAF LFD D   KIS+ NL+ ++  LGEN+TDEEL+ M+   D+D  GE+NE +F  IM  ++
Sbjct:   22 ELGEEQRQEIKEAFNLFDTDKDQAIDYHELKVAMRALGFDVKKADVLKIMKDYDRESTGKISFDDFNEVMTDWMLDRDPQEEVFKAFRLFDDDDSGKISLRNLRRVARELGENMTDEELRAMIDEFDKDGDGEINEDEFLAIMTGDT 168
[Close]
BLAST of Centrin vs. Ensembl Nematostella
Match: EDO46518 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RPI8])

HSP 1 Score: 123.25 bits (308), Expect = 1.992e-36
Identity = 64/146 (43.84%), Postives = 97/146 (66.44%), Query Frame = 2 
Query:   77 MTIELSEKQKEDIQKAFNLFDKDGSGTIDIQEVKVALRALDFEPLKDDIRKLISEYDKDNKGTIDFNNFLILISSKMTEPDSKEDITKAFNLFDKDGKEKISIHNLKSISEILGENLTDEELQEMLFNADRDNPGEVNERDFHRIM 514
            M  +L+E+Q  + ++AF+LFDKDG GTI  +E+   +R+L   P + +++ +I+E D D  GTIDF  FL +++ KM + DS+E+I +AF +FDKDG   IS   L+ +   LGE LTDEE+ EM+  AD D  G+VN  +F ++M
Sbjct:    1 MADQLTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGFISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVKMM 146

HSP 2 Score: 46.2098 bits (108), Expect = 8.121e-7
Identity = 23/61 (37.70%), Postives = 37/61 (60.66%), Query Frame = 2 
Query:  338 KAFNLFDKDGKEKISIHNLKSISEILGENLTDEELQEMLFNADRDNPGEVNERDFHRIMKK 520
            +AF+LFDKDG   I+   L ++   LG+N T+ ELQ+M+   D D  G ++  +F  +M +
Sbjct:   15 EAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPEFLTMMAR 75

HSP 3 Score: 44.2838 bits (103), Expect = 3.862e-6
Identity = 21/67 (31.34%), Postives = 43/67 (64.18%), Query Frame = 2 
Query:  104 KEDIQKAFNLFDKDGSGTIDIQEVKVALRALDFEPLKDDIRKLISEYDKDNKGTIDFNNFLILISSK 304
            +E+I++AF +FDKDG+G I   E++  +  L  +   +++ ++I E D D  G +++  F+ +++SK
Sbjct:   83 EEEIREAFRVFDKDGNGFISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVKMMTSK 149
[Close]
BLAST of Centrin vs. Ensembl Nematostella
Match: EDO46606 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RPN8])

HSP 1 Score: 115.931 bits (289), Expect = 1.241e-33
Identity = 60/135 (44.44%), Postives = 89/135 (65.93%), Query Frame = 2 
Query:  110 DIQKAFNLFDKDGSGTIDIQEVKVALRALDFEPLKDDIRKLISEYDKDNKGTIDFNNFLILISSKMTEPDSKEDITKAFNLFDKDGKEKISIHNLKSISEILGENLTDEELQEMLFNADRDNPGEVNERDFHRIM 514
            + ++AF+LFDKDG GTI  +E+   +R+L   P + +++ +I+E D D  GTIDF  FL +++ KM   DS+E+I +AF +FDKDG   IS   L+ +   LGE LTDEE+ EM+  AD D  G+VN  +F ++M
Sbjct:    3 EFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPEFLTMMARKMKNTDSEEEIREAFRVFDKDGNGFISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYDEFVKMM 137

HSP 2 Score: 46.2098 bits (108), Expect = 6.970e-7
Identity = 23/61 (37.70%), Postives = 37/61 (60.66%), Query Frame = 2 
Query:  338 KAFNLFDKDGKEKISIHNLKSISEILGENLTDEELQEMLFNADRDNPGEVNERDFHRIMKK 520
            +AF+LFDKDG   I+   L ++   LG+N T+ ELQ+M+   D D  G ++  +F  +M +
Sbjct:    6 EAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPEFLTMMAR 66

HSP 3 Score: 44.669 bits (104), Expect = 2.424e-6
Identity = 21/67 (31.34%), Postives = 44/67 (65.67%), Query Frame = 2 
Query:  104 KEDIQKAFNLFDKDGSGTIDIQEVKVALRALDFEPLKDDIRKLISEYDKDNKGTIDFNNFLILISSK 304
            +E+I++AF +FDKDG+G I   E++  +  L  +   +++ ++I E D D  G ++++ F+ +++SK
Sbjct:   74 EEEIREAFRVFDKDGNGFISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYDEFVKMMTSK 140
[Close]
BLAST of Centrin vs. Ensembl Nematostella
Match: EDO30674 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7T043])

HSP 1 Score: 114.39 bits (285), Expect = 1.096e-32
Identity = 54/146 (36.99%), Postives = 100/146 (68.49%), Query Frame = 2 
Query:   83 IELSEKQKEDIQKAFNLFDKDGSGTIDIQEVKVALRALDFEPLKDDIRKLISEYDKDNKGTIDFNNFLILISSKMTEPDSKEDITKAFNLFDKDGKEKISIHNLKSISEILGENLTDEELQEMLFNADRDNPGEVNERDFHRIMKK 520
             EL+ +Q+ ++Q+AF+LFDKDGSGTI  +E++V +++L   P  ++++++I E D D  G +DF  FL ++  +M   D++ ++ +AF +FD++G   IS   L+S+   LGE L+D+E++EM+  AD D  G +N ++F +++++
Sbjct:   11 FELTAEQRNELQEAFSLFDKDGSGTISNEELEVVMKSLGQNPSDEELQQMIQEVDADGNGEVDFEEFLAMMKKQMQHRDAEAEMREAFRVFDRNGDGSISEWELRSVMASLGEKLSDDEIKEMMREADLDGDGVINFQEFVQMVRE 156

HSP 2 Score: 43.5134 bits (101), Expect = 9.872e-6
Identity = 19/71 (26.76%), Postives = 43/71 (60.56%), Query Frame = 2 
Query:  110 DIQKAFNLFDKDGSGTIDIQEVKVALRALDFEPLKDDIRKLISEYDKDNKGTIDFNNFLILISSKMTEPDS 322
            ++++AF +FD++G G+I   E++  + +L  +   D+I++++ E D D  G I+F  F+ ++     +P+ 
Sbjct:   93 EMREAFRVFDRNGDGSISEWELRSVMASLGEKLSDDEIKEMMREADLDGDGVINFQEFVQMVREMDKQPEG 163
[Close]
BLAST of Centrin vs. Ensembl Medaka
Match: cetn2 (caltractin [Source:NCBI gene;Acc:101170769])

HSP 1 Score: 175.637 bits (444), Expect = 2.850e-56
Identity = 88/149 (59.06%), Postives = 114/149 (76.51%), Query Frame = 2 
Query:   86 ELSEKQKEDIQKAFNLFDKDGSGTIDIQEVKVALRALDFEPLKDDIRKLISEYDKDNKGTIDFNNFLILISSKMTEPDSKEDITKAFNLFDKDGKEKISIHNLKSISEILGENLTDEELQEMLFNADRDNPGEVNERDFHRIMKKNSFY 532
            EL+E+QK++I++AF LFD DGSG ID++++KVA+RAL FEP K++I+K+I E DKD  G I F +FL +++ KM E DSKE+I KAF LFD D   KIS  NLK +++ LGENLTDEELQEM+  ADRD  GEVN+ +F RIMKK   Y
Sbjct:   27 ELTEEQKQEIREAFELFDTDGSGFIDVKDLKVAMRALGFEPKKEEIKKMIGEVDKDATGKISFADFLTVMTQKMAEKDSKEEILKAFRLFDDDETGKISFRNLKRVAKELGENLTDEELQEMIDEADRDGDGEVNQEEFLRIMKKTCLY 175
[Close]
BLAST of Centrin vs. Ensembl Medaka
Match: cetn2 (caltractin [Source:NCBI gene;Acc:101170769])

HSP 1 Score: 175.637 bits (444), Expect = 2.850e-56
Identity = 88/149 (59.06%), Postives = 114/149 (76.51%), Query Frame = 2 
Query:   86 ELSEKQKEDIQKAFNLFDKDGSGTIDIQEVKVALRALDFEPLKDDIRKLISEYDKDNKGTIDFNNFLILISSKMTEPDSKEDITKAFNLFDKDGKEKISIHNLKSISEILGENLTDEELQEMLFNADRDNPGEVNERDFHRIMKKNSFY 532
            EL+E+QK++I++AF LFD DGSG ID++++KVA+RAL FEP K++I+K+I E DKD  G I F +FL +++ KM E DSKE+I KAF LFD D   KIS  NLK +++ LGENLTDEELQEM+  ADRD  GEVN+ +F RIMKK   Y
Sbjct:   27 ELTEEQKQEIREAFELFDTDGSGFIDVKDLKVAMRALGFEPKKEEIKKMIGEVDKDATGKISFADFLTVMTQKMAEKDSKEEILKAFRLFDDDETGKISFRNLKRVAKELGENLTDEELQEMIDEADRDGDGEVNQEEFLRIMKKTCLY 175
[Close]
BLAST of Centrin vs. Ensembl Medaka
Match: calm2a (calmodulin 2 [Source:NCBI gene;Acc:100049420])

HSP 1 Score: 124.02 bits (310), Expect = 2.648e-36
Identity = 64/146 (43.84%), Postives = 97/146 (66.44%), Query Frame = 2 
Query:   77 MTIELSEKQKEDIQKAFNLFDKDGSGTIDIQEVKVALRALDFEPLKDDIRKLISEYDKDNKGTIDFNNFLILISSKMTEPDSKEDITKAFNLFDKDGKEKISIHNLKSISEILGENLTDEELQEMLFNADRDNPGEVNERDFHRIM 514
            M  +L+E+Q  + ++AF+LFDKDG GTI  +E+   +R+L   P + +++ +I+E D D  GTIDF  FL +++ KM + DS+E+I +AF +FDKDG   IS   L+ +   LGE LTDEE+ EM+  AD D  G+VN  +F ++M
Sbjct:    1 MADQLTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVQMM 146

HSP 2 Score: 46.2098 bits (108), Expect = 2.081e-6
Identity = 23/61 (37.70%), Postives = 37/61 (60.66%), Query Frame = 2 
Query:  338 KAFNLFDKDGKEKISIHNLKSISEILGENLTDEELQEMLFNADRDNPGEVNERDFHRIMKK 520
            +AF+LFDKDG   I+   L ++   LG+N T+ ELQ+M+   D D  G ++  +F  +M +
Sbjct:   15 EAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPEFLTMMAR 75
[Close]
BLAST of Centrin vs. Ensembl Medaka
Match: ENSORLT00000008599.2 (calmodulin 3 [Source:NCBI gene;Acc:100049421])

HSP 1 Score: 124.02 bits (310), Expect = 2.648e-36
Identity = 64/146 (43.84%), Postives = 97/146 (66.44%), Query Frame = 2 
Query:   77 MTIELSEKQKEDIQKAFNLFDKDGSGTIDIQEVKVALRALDFEPLKDDIRKLISEYDKDNKGTIDFNNFLILISSKMTEPDSKEDITKAFNLFDKDGKEKISIHNLKSISEILGENLTDEELQEMLFNADRDNPGEVNERDFHRIM 514
            M  +L+E+Q  + ++AF+LFDKDG GTI  +E+   +R+L   P + +++ +I+E D D  GTIDF  FL +++ KM + DS+E+I +AF +FDKDG   IS   L+ +   LGE LTDEE+ EM+  AD D  G+VN  +F ++M
Sbjct:    1 MADQLTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVQMM 146

HSP 2 Score: 46.2098 bits (108), Expect = 2.081e-6
Identity = 23/61 (37.70%), Postives = 37/61 (60.66%), Query Frame = 2 
Query:  338 KAFNLFDKDGKEKISIHNLKSISEILGENLTDEELQEMLFNADRDNPGEVNERDFHRIMKK 520
            +AF+LFDKDG   I+   L ++   LG+N T+ ELQ+M+   D D  G ++  +F  +M +
Sbjct:   15 EAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPEFLTMMAR 75
[Close]
BLAST of Centrin vs. Ensembl Medaka
Match: calm1b (calmodulin [Source:NCBI gene;Acc:100049419])

HSP 1 Score: 124.02 bits (310), Expect = 2.648e-36
Identity = 64/146 (43.84%), Postives = 97/146 (66.44%), Query Frame = 2 
Query:   77 MTIELSEKQKEDIQKAFNLFDKDGSGTIDIQEVKVALRALDFEPLKDDIRKLISEYDKDNKGTIDFNNFLILISSKMTEPDSKEDITKAFNLFDKDGKEKISIHNLKSISEILGENLTDEELQEMLFNADRDNPGEVNERDFHRIM 514
            M  +L+E+Q  + ++AF+LFDKDG GTI  +E+   +R+L   P + +++ +I+E D D  GTIDF  FL +++ KM + DS+E+I +AF +FDKDG   IS   L+ +   LGE LTDEE+ EM+  AD D  G+VN  +F ++M
Sbjct:    1 MADQLTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVQMM 146

HSP 2 Score: 46.2098 bits (108), Expect = 2.081e-6
Identity = 23/61 (37.70%), Postives = 37/61 (60.66%), Query Frame = 2 
Query:  338 KAFNLFDKDGKEKISIHNLKSISEILGENLTDEELQEMLFNADRDNPGEVNERDFHRIMKK 520
            +AF+LFDKDG   I+   L ++   LG+N T+ ELQ+M+   D D  G ++  +F  +M +
Sbjct:   15 EAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPEFLTMMAR 75
[Close]
BLAST of Centrin vs. Planmine SMEST
Match: SMESG000040368.1 (SMESG000040368.1)

HSP 1 Score: 257.299 bits (656), Expect = 3.342e-89
Identity = 133/136 (97.79%), Postives = 134/136 (98.53%), Query Frame = 2 
Query:   50 MNSKKKVDKMTIELSEKQKEDIQKAFNLFDKDGSGTIDIQEVKVALRALDFEPLKDDIRKLISEYDKDNKGTIDFNNFLILISSKMTEPDSKEDITKAFNLFDKDGKEKISIHNLKSISEILGENLTDEELQEMLF 457
            MNSKKKVDKMTIELSEKQKEDIQKAFNLFDKDGSGTIDIQEVKVALRALDFEPLKDDIRKLISEYDKDNKGTIDFNNFLILISSKMTEPDSKEDITKAFNLFDKDGKEKISIHNLKSISEILGENLTDEELQ +L 
Sbjct:    1 MNSKKKVDKMTIELSEKQKEDIQKAFNLFDKDGSGTIDIQEVKVALRALDFEPLKDDIRKLISEYDKDNKGTIDFNNFLILISSKMTEPDSKEDITKAFNLFDKDGKEKISIHNLKSISEILGENLTDEELQVVLL 136
[Close]
BLAST of Centrin vs. Planmine SMEST
Match: SMESG000015458.1 (SMESG000015458.1)

HSP 1 Score: 168.703 bits (426), Expect = 1.308e-53
Identity = 86/149 (57.72%), Postives = 117/149 (78.52%), Query Frame = 2 
Query:   86 ELSEKQKEDIQKAFNLFDKDGSGTIDIQEVKVALRALDFEPLKDDIRKLISEYDKDNKGTIDFNNFLILISSKMTEPDSKEDITKAFNLFDKDGKEKISIHNLKSISEILGENLTDEELQEMLFNADRDNPGEVNERDFHRIMKKNSFY 532
            EL+E+QK+++++AF+LFD DGSGTIDI+E+KVA+RAL FEP K+++RKLI++YD + KG I+F++FL +++ KM E D+KE+I KAF LFD D  EK  +   KS   I   NLTDEELQEM+  ADRDN GE+NE++F RIMKK + Y
Sbjct:   25 ELTEEQKQEVREAFDLFDADGSGTIDIKELKVAMRALGFEPKKEEVRKLIADYDIEGKGIIEFSDFLSMMTQKMAEKDTKEEILKAFKLFDDDETEKFLLKFKKSCKRIR-RNLTDEELQEMIDEADRDNDGEINEQEFLRIMKKTNLY 172
[Close]
BLAST of Centrin vs. Planmine SMEST
Match: SMESG000052182.1 (SMESG000052182.1)

HSP 1 Score: 137.887 bits (346), Expect = 2.584e-42
Identity = 68/116 (58.62%), Postives = 91/116 (78.45%), Query Frame = 2 
Query:  185 LRALDFEPLKDDIRKLISEYDKDNKGTIDFNNFLILISSKMTEPDSKEDITKAFNLFDKDGKEKISIHNLKSISEILGENLTDEELQEMLFNADRDNPGEVNERDFHRIMKKNSFY 532
            +RAL FEP K+++RKLI++YD + KG I+F++FL +++ KM E D+KE+I KAF LFD D   KIS  NLK +++ LGENLTDEELQEM+  ADRDN GE+NE++F RIMKK + Y
Sbjct:    1 MRALGFEPKKEEVRKLIADYDIEGKGIIEFSDFLSMMTQKMAEKDTKEEILKAFKLFDDDETGKISFKNLKRVAKELGENLTDEELQEMIDEADRDNDGEINEQEFLRIMKKTNLY 116
[Close]
BLAST of Centrin vs. Planmine SMEST
Match: SMESG000015458.1 (SMESG000015458.1)

HSP 1 Score: 122.094 bits (305), Expect = 5.133e-36
Identity = 64/116 (55.17%), Postives = 85/116 (73.28%), Query Frame = 2 
Query:  185 LRALDFEPLKDDIRKLISEYDKDNKGTIDFNNFLILISSKMTEPDSKEDITKAFNLFDKDGKEKISIHNLKSISEILGENLTDEELQEMLFNADRDNPGEVNERDFHRIMKKNSFY 532
            +RAL FEP K+++RKLI++YD + KG I+F++FL +++ KM E D+KE+I KAF LFD D  EK  +   KS   I   NLTDEELQEM+  ADRDN GE+NE++F RIMKK + Y
Sbjct:    1 MRALGFEPKKEEVRKLIADYDIEGKGIIEFSDFLSMMTQKMAEKDTKEEILKAFKLFDDDETEKFLLKFKKSCKRI-RRNLTDEELQEMIDEADRDNDGEINEQEFLRIMKKTNLY 115
[Close]
BLAST of Centrin vs. Planmine SMEST
Match: SMESG000034095.1 (SMESG000034095.1)

HSP 1 Score: 122.094 bits (305), Expect = 1.076e-35
Identity = 64/146 (43.84%), Postives = 96/146 (65.75%), Query Frame = 2 
Query:   77 MTIELSEKQKEDIQKAFNLFDKDGSGTIDIQEVKVALRALDFEPLKDDIRKLISEYDKDNKGTIDFNNFLILISSKMTEPDSKEDITKAFNLFDKDGKEKISIHNLKSISEILGENLTDEELQEMLFNADRDNPGEVNERDFHRIM 514
            M  +L+E+Q  + ++AF+LFDKDG GTI  +E+   +R+L   P + +++ +I+E D D  GTIDF  FL +++ KM + DS+E+I +AF +FDKDG   IS   L+ +   LGE LTDEE+ EM+  AD D  G+VN  +F  +M
Sbjct:    1 MADQLTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGFISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVTMM 146

HSP 2 Score: 46.2098 bits (108), Expect = 1.419e-6
Identity = 23/61 (37.70%), Postives = 37/61 (60.66%), Query Frame = 2 
Query:  338 KAFNLFDKDGKEKISIHNLKSISEILGENLTDEELQEMLFNADRDNPGEVNERDFHRIMKK 520
            +AF+LFDKDG   I+   L ++   LG+N T+ ELQ+M+   D D  G ++  +F  +M +
Sbjct:   15 EAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPEFLTMMAR 75

HSP 3 Score: 44.2838 bits (103), Expect = 6.688e-6
Identity = 20/67 (29.85%), Postives = 43/67 (64.18%), Query Frame = 2 
Query:  104 KEDIQKAFNLFDKDGSGTIDIQEVKVALRALDFEPLKDDIRKLISEYDKDNKGTIDFNNFLILISSK 304
            +E+I++AF +FDKDG+G I   E++  +  L  +   +++ ++I E D D  G +++  F+ ++++K
Sbjct:   83 EEEIREAFRVFDKDGNGFISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVTMMTTK 149
The following BLAST results are available for this feature:
BLAST of Centrin vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5
Match NameE-valueIdentityDescription
CETN27.723e-5859.06centrin 2 [Source:HGNC Symbol;Acc:HGNC:1867][more]
CETN11.752e-5759.73centrin 1 [Source:HGNC Symbol;Acc:HGNC:1866][more]
CALM24.942e-3643.84calmodulin 2 [Source:HGNC Symbol;Acc:HGNC:1445][more]
CALM24.942e-3643.84calmodulin 2 [Source:HGNC Symbol;Acc:HGNC:1445][more]
CALM14.942e-3643.84calmodulin 1 [Source:HGNC Symbol;Acc:HGNC:1442][more]
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BLAST of Centrin vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 5
Match NameE-valueIdentityDescription
cmd-11.026e-3543.84Calmodulin [Source:UniProtKB/Swiss-Prot;Acc:O1630... [more]
cal-15.442e-2534.97Calmodulin-like protein [Source:UniProtKB/Swiss-P... [more]
cal-19.438e-2534.97Calmodulin-like protein [Source:UniProtKB/Swiss-P... [more]
cmd-13.356e-2443.64Calmodulin [Source:UniProtKB/Swiss-Prot;Acc:O1630... [more]
cal-45.969e-2134.62CALmodulin related genes [Source:UniProtKB/TrEMBL... [more]
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BLAST of Centrin vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5
Match NameE-valueIdentityDescription
CG174932.931e-5358.39gene:FBgn0040010 transcript:FBtr0332630[more]
CG174932.931e-5358.39gene:FBgn0040010 transcript:FBtr0332632[more]
CG174932.931e-5358.39gene:FBgn0040010 transcript:FBtr0332631[more]
CG318027.202e-4250.00gene:FBgn0051802 transcript:FBtr0081058[more]
Cam1.359e-3543.84gene:FBgn0000253 transcript:FBtr0304964[more]
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BLAST of Centrin vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
cetn43.826e-5856.17centrin 4 [Source:ZFIN;Acc:ZDB-GENE-030826-21][more]
cetn25.083e-5759.06centrin, EF-hand protein, 2 [Source:ZFIN;Acc:ZDB-G... [more]
calm3a3.144e-3643.84calmodulin 3a (phosphorylase kinase, delta) [Sourc... [more]
calm3b3.144e-3643.84calmodulin 3b (phosphorylase kinase, delta) [Sourc... [more]
calm1b3.144e-3643.84calmodulin 1b [Source:ZFIN;Acc:ZDB-GENE-030804-2][more]
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BLAST of Centrin vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5
Match NameE-valueIdentityDescription
dtl2.351e-5860.40denticleless E3 ubiquitin protein ligase homolog [... [more]
dtl6.345e-5860.40denticleless E3 ubiquitin protein ligase homolog [... [more]
cetn11.319e-5757.41centrin 1 [Source:NCBI gene;Acc:549903][more]
cetn13.426e-5759.06centrin 1 [Source:NCBI gene;Acc:549903][more]
CALM24.479e-3643.84calmodulin 1 (phosphorylase kinase, delta) [Source... [more]
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BLAST of Centrin vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Cetn25.409e-5957.32centrin 2 [Source:MGI Symbol;Acc:MGI:1347085][more]
Cetn21.224e-5860.40centrin 2 [Source:MGI Symbol;Acc:MGI:1347085][more]
Cetn21.224e-5860.40centrin 2 [Source:MGI Symbol;Acc:MGI:1347085][more]
Cetn11.803e-5658.39centrin 1 [Source:MGI Symbol;Acc:MGI:1347086][more]
Cetn11.803e-5658.39centrin 1 [Source:MGI Symbol;Acc:MGI:1347086][more]
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BLAST of Centrin vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|Q9R1K9|CETN2_MOUSE3.784e-5857.32Centrin-2 OS=Mus musculus OX=10090 GN=Cetn2 PE=1 S... [more]
sp|P43646|CATR_TETST4.805e-5860.81Caltractin (Fragment) OS=Tetraselmis striata OX=31... [more]
sp|Q06827|CATR_SCHDU1.571e-5760.14Caltractin OS=Scherffelia dubia OX=3190 PE=1 SV=1[more]
sp|Q2TBN3|CETN2_BOVIN2.476e-5759.06Centrin-2 OS=Bos taurus OX=9913 GN=CETN2 PE=2 SV=1[more]
sp|P41208|CETN2_HUMAN3.709e-5759.06Centrin-2 OS=Homo sapiens OX=9606 GN=CETN2 PE=1 SV... [more]
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BLAST of Centrin vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
A0A1I8IGH52.544e-6263.13Uncharacterized protein OS=Macrostomum lignano OX=... [more]
A0A267EVD42.750e-6263.92Uncharacterized protein (Fragment) OS=Macrostomum ... [more]
A0A267ED523.344e-6263.13Uncharacterized protein (Fragment) OS=Macrostomum ... [more]
A0A1I8II504.492e-6263.13Uncharacterized protein OS=Macrostomum lignano OX=... [more]
A0A1S3GYU66.990e-6160.49caltractin OS=Lingula unguis OX=7574 GN=LOC1061505... [more]
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BLAST of Centrin vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
cetn44.227e-6158.02caltractin [Source:NCBI gene;Acc:103037928][more]
cetn44.468e-6158.02caltractin [Source:NCBI gene;Acc:103037928][more]
cetn21.356e-5658.39centrin-1 [Source:NCBI gene;Acc:103028142][more]
cetn31.130e-3644.90centrin 3 [Source:NCBI gene;Acc:103024517][more]
calm3a2.664e-3643.84calmodulin [Source:NCBI gene;Acc:103037741][more]
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BLAST of Centrin vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 5
Match NameE-valueIdentityDescription
CETN15.811e-6059.73centrin 1 [Source:HGNC Symbol;Acc:HGNC:1866][more]
ENSPMAT00000006008.11.550e-3743.84pep scaffold:Pmarinus_7.0:GL476713:142259:146509:-... [more]
CALM35.404e-3743.84calmodulin 3 [Source:HGNC Symbol;Acc:HGNC:1449][more]
CALML31.059e-3644.06calmodulin like 3 [Source:HGNC Symbol;Acc:HGNC:145... [more]
cetn35.014e-3640.14centrin 3 [Source:ZFIN;Acc:ZDB-GENE-050522-152][more]
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BLAST of Centrin vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 4
Match NameE-valueIdentityDescription
CDC311.391e-3344.60Calcium-binding component of the spindle pole body... [more]
CMD12.188e-2635.81Calmodulin; Ca2+ binding protein that regulates Ca... [more]
MLC18.266e-1433.33Essential light chain for Myo1p; light chain for M... [more]
CNB11.365e-731.62Calcineurin B; regulatory subunit of calcineurin, ... [more]
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BLAST of Centrin vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 5
Match NameE-valueIdentityDescription
EDO407751.521e-6163.09Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO449442.030e-3744.22Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO465181.992e-3643.84Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO466061.241e-3344.44Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO306741.096e-3236.99Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
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BLAST of Centrin vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5
Match NameE-valueIdentityDescription
cetn22.850e-5659.06caltractin [Source:NCBI gene;Acc:101170769][more]
cetn22.850e-5659.06caltractin [Source:NCBI gene;Acc:101170769][more]
calm2a2.648e-3643.84calmodulin 2 [Source:NCBI gene;Acc:100049420][more]
ENSORLT00000008599.22.648e-3643.84calmodulin 3 [Source:NCBI gene;Acc:100049421][more]
calm1b2.648e-3643.84calmodulin [Source:NCBI gene;Acc:100049419][more]
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BLAST of Centrin vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5
Match NameE-valueIdentityDescription
SMESG000040368.13.342e-8997.79SMESG000040368.1[more]
SMESG000015458.11.308e-5357.72SMESG000015458.1[more]
SMESG000052182.12.584e-4258.62SMESG000052182.1[more]
SMESG000015458.15.133e-3655.17SMESG000015458.1[more]
SMESG000034095.11.076e-3543.84SMESG000034095.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30013731 ID=SMED30013731|Name=Centrin|organism=Schmidtea mediterranea sexual|type=transcript|length=542bp
CTATAGTAATTATAAATAAAAGAAATTAAATTATTACAACAAATTTACTA
TGAATTCTAAAAAAAAAGTGGATAAAATGACTATTGAATTAAGTGAAAAA
CAAAAAGAAGACATTCAAAAAGCTTTCAATCTATTCGATAAGGATGGTTC
CGGAACAATTGATATTCAAGAAGTAAAAGTTGCTTTACGAGCCTTAGATT
TCGAACCACTTAAAGATGACATAAGGAAATTAATTTCAGAATACGACAAA
GATAATAAAGGAACGATTGATTTTAATAATTTTTTAATTCTAATAAGTTC
TAAGATGACAGAGCCAGATTCAAAAGAAGACATAACGAAAGCTTTTAATC
TATTTGACAAAGATGGAAAGGAAAAAATATCAATTCATAATTTAAAATCA
ATATCTGAAATTTTGGGTGAAAATCTTACTGATGAAGAACTTCAGGAAAT
GCTGTTTAACGCTGACAGAGACAACCCTGGAGAAGTAAATGAAAGAGATT
TTCATCGTATCATGAAAAAAAATTCTTTTTATTAAAAAAAAA
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protein sequence of SMED30013731-orf-1

>SMED30013731-orf-1 ID=SMED30013731-orf-1|Name=SMED30013731-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=162bp
MNSKKKVDKMTIELSEKQKEDIQKAFNLFDKDGSGTIDIQEVKVALRALD
FEPLKDDIRKLISEYDKDNKGTIDFNNFLILISSKMTEPDSKEDITKAFN
LFDKDGKEKISIHNLKSISEILGENLTDEELQEMLFNADRDNPGEVNERD
FHRIMKKNSFY*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000016pharynx
PLANA:0000020protonephridia
PLANA:0000034epidermis
PLANA:0000099neuron
PLANA:0000418head
PLANA:0002032epidermal cell
Vocabulary: INTERPRO
TermDefinition
IPR002048EF_hand_dom
IPR011992EF-hand-dom_pair
IPR018247EF_Hand_1_Ca_BS
Vocabulary: molecular function
TermDefinition
GO:0005509calcium ion binding
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR002048EF-hand domainSMARTSM00054efh_1coord: 130..158
e-value: 1.8
score: 15.7
coord: 94..122
e-value: 2.2
score: 14.9
coord: 21..49
e-value: 2.6E-7
score: 40.3
coord: 57..85
e-value: 3.2E-4
score: 30.0
IPR002048EF-hand domainPFAMPF13499EF-hand_7coord: 93..156
e-value: 7.5E-8
score: 32.7
coord: 19..81
e-value: 6.8E-12
score: 45.7
IPR002048EF-hand domainPROSITEPS50222EF_HAND_2coord: 17..52
score: 16.327
IPR002048EF-hand domainPROSITEPS50222EF_HAND_2coord: 90..125
score: 11.305
IPR002048EF-hand domainPROSITEPS50222EF_HAND_2coord: 53..88
score: 11.891
IPR002048EF-hand domainPROSITEPS50222EF_HAND_2coord: 126..161
score: 7.986
NoneNo IPR availableGENE3DG3DSA:1.10.238.10coord: 1..79
e-value: 3.0E-21
score: 77.2
NoneNo IPR availableGENE3DG3DSA:1.10.238.10coord: 80..160
e-value: 4.0E-20
score: 73.8
NoneNo IPR availablePANTHERPTHR23050CALCIUM BINDING PROTEINcoord: 6..161
NoneNo IPR availablePANTHERPTHR23050:SF350CENTRIN-4coord: 6..161
IPR018247EF-Hand 1, calcium-binding sitePROSITEPS00018EF_HAND_1coord: 30..42
IPR011992EF-hand domain pairSUPERFAMILYSSF47473EF-handcoord: 9..157