Sterol O-acyltransferase 1
Overview
Neoblast Clusters
Zeng et. al., 2018▻ Overview▻ Neoblast Population▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Overview
Single cell RNA-seq of pluripotent neoblasts and its early progeniesWe isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)Explore this single cell expression dataset with our NB Cluster Shiny App
Neoblast Population
Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Embryonic Expression
Davies et. al., 2017
Hover the mouse over a column in the graph to view average RPKM values per sample. Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult. back to top Anatomical Expression
PAGE et. al., 2020SMED30013721 has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGEPAGE Curations: 8
Homology
BLAST of Sterol O-acyltransferase 1 vs. Ensembl Human
Match: AXDND1 (axonemal dynein light chain domain containing 1 [Source:HGNC Symbol;Acc:HGNC:26564]) HSP 1 Score: 144.821 bits (364), Expect = 3.316e-61 Identity = 134/526 (25.48%), Postives = 250/526 (47.53%), Query Frame = 3 Query: 876 VVARKILDRRLTEELLRFQNTVSMLSKELSGVKDHEENINQICKQAKLQLKEAVEETKTNADLLREYHDLYEQQRQRLERNVLQLERERDCWRNAAYKITQLVLEHYEIKPAIVLVECESNMISLSQYFVELISVTDNQTLSTIKTKTTQWCNEAQKFALMLAIREENLKTLLNKEIEKINRLKEDF-EDDYLSEQGQLIQPINQEETRKILNSVI----NWEKSMSEICESFGGQSMLMEEEKLKHMKQLCYEYTDIAVEVFNRHRNETDGSLYQEHSALLDINKLIDEMMTQFMDQLTGDNGVADGIIALQTFEENWITRLSNSVAELYFRPLPDSEWIRFKLLLDDWIALLCESKNAIGTTKLNSITVEGASINKRLEIHEIIQSVDNWSQKSSSGIESENLKLREAIINLKKSMIRWTSQVILRLAPDFPDNSPEAR---RAARLASLGIRELQETAKVLHENISAVSNHIFNCSKDIVTKLMQIKIDTQTEFPDGDSLKLHQLIEFSKSWIEKSEQLLKEI 2429 +V ++++D+R+ EEL F++ + L++EL V+ H+ + + ++A L +A+ + NA ++ EYHDLY QR+R+E ++ +L ERD W +A Y++ V+E + A L E +++F+ L+S D + L+ ++ T +W N K + EE+ L + + + +E F E D LS I NSV+ W+K ++E E F G +L + + LK +K L + DI + +FNRH++ +G + E + +I K I ++ ++ ++ GDNG + + +L + + +L N L F P EW +++ + L N G I V+ S+ L+ + I + W K + I + N++L+ + L SMI+W +++ + P+F D + +A +G+ L+ A L + S+++ +C K +VT + K + D ++ +L + WI LL I Sbjct: 309 LVTQRVMDQRILEELYNFKHVIEELTRELCLVRAHDVKLTKETEKAHKDLAQALLNAEKNAKIVEEYHDLYTLQRERMENDMKKLVAERDIWSSATYELALKVIERNRVILARRLYLNEKGWNKYTKHFIILLSNKDTEDLALLQKLTQKWRNLVNKLKQEVEQMEESTSETLKIVKDGLIKWQEFFNEKDILSPNKG-----------NIFNSVLLDFKQWQKILNEKKEEFTGDVLLSKYDTLKIIKHLQENWADIGLGIFNRHKS-LEGEMPSERQYMEEIIKNIQKLYKEYEIRINGDNGYSKILPSLISSLDFCSFKLEN----LEFPDTPLEEWQEIDEKINEMKSHLDILLNLTGIVP-QHIDVDSVSV---LQAY-IFNMIQQWLLKIGNEINNGNIELQHHMDELHISMIQWMVNLLILMIPNFTDQDCLLKLEEESAEKHDIGVARLELDAIELTRKLYQYSSYLSSCCKGMVTAMALSKSTNSHKNATEDLYEVDKLKKECYEWINTCSCLLSNI 813 HSP 2 Score: 112.849 bits (281), Expect = 3.316e-61 Identity = 83/274 (30.29%), Postives = 139/274 (50.73%), Query Frame = 1 Query: 103 LPLLKFKENYSTHSKPAVKPIP-AFLSDEILTNLQQCTNALVCPH-----------EGK----VSNVWSSVIRREKFKHISDNPICICGAGNDLTFLYD--KLPNEIIEHFSDPLINXXXXXXXXXXIEDKMLMRLPEKLDPAEFTLSTHQGMREIQLYDESFTTKPFPHKYHKXXXXXXXXXXXXXXXKIYQSFGDVLDKSGLNEPFEFNMPTVLHNLLMTVKKEQDLYNVVFHEVIKETTIDCIERGELLANIRQRYRNLFFKIPEKIKEFH 870 LP LK K+N SK + F+ E+L +L NA CP +G V +VW +RR KFK++ D+P+ + GAG D++FLYD + E P + + I L + L P EF + + G+ ++ YD+ +TT + + P M PN ++ +L+++G+ E E+ PT +H LL +KKEQ +YN++FHE+I++ ++DC +RGELL+ +R+RY + +I ++ +F+ Sbjct: 34 LPELKEKKNMVDRSKLLPTSLQNEFIPKEVLLSLTYAANAGPCPENLLPPKKIKTPKGTLPRLVDHVWHHPVRRNKFKYLIDHPVSLTGAGRDISFLYDVTYAKGQTREKAVCPPHLARSLQSHDGVIVPHKPKTLTDTLIPEEFHIVSSTGVSGLECYDDKYTTLLTDSENRLLLFPSMKPNKRVEVAQLNDVMDTMLERAGV-ENQEYTGPTKMHKLLHILKKEQTIYNMIFHELIRQVSVDCADRGELLSKVRERYVQMLDQIARQMIDFY 306
BLAST of Sterol O-acyltransferase 1 vs. Ensembl Human
Match: AXDND1 (axonemal dynein light chain domain containing 1 [Source:HGNC Symbol;Acc:HGNC:26564]) HSP 1 Score: 144.821 bits (364), Expect = 3.251e-59 Identity = 126/486 (25.93%), Postives = 237/486 (48.77%), Query Frame = 3 Query: 876 VVARKILDRRLTEELLRFQNTVSMLSKELSGVKDHEENINQICKQAKLQLKEAVEETKTNADLLREYHDLYEQQRQRLERNVLQLERERDCWRNAAYKITQLVLEHYEIKPAIVLVECESNMISLSQYFVELISVTDNQTLSTIKTKTTQWCNEAQKFALMLAIREENLKTLLNKEIEKINRLKEDF-EDDYLSEQGQLIQPINQEETRKILNSVI----NWEKSMSEICESFGGQSMLMEEEKLKHMKQLCYEYTDIAVEVFNRHRNETDGSLYQEHSALLDINKLIDEMMTQFMDQLTGDNGVADGIIALQTFEENWITRLSNSVAELYFRPLPDSEWIRFKLLLDDWIALLCESKNAIGTTKLNSITVEGASINKRLEIHEIIQSVDNWSQKSSSGIESENLKLREAIINLKKSMIRWTSQVILRLAPDFPDNSPEAR---RAARLASLGIRELQETAKVLHENISAVSNHIFNCSKDIVTKL 2309 +V ++++D+R+ EEL F++ + L++EL V+ H+ + + ++A L +A+ + NA ++ EYHDLY QR+R+E ++ +L ERD W +A Y++ V+E + A L E +++F+ L+S D + L+ ++ T +W N K + EE+ L + + + +E F E D LS I NSV+ W+K ++E E F G +L + + LK +K L + DI + +FNRH++ +G + E + +I K I ++ ++ ++ GDNG + + +L + + +L N L F P EW +++ + L N G I V+ S+ L+ + I + W K + I + N++L+ + L SMI+W +++ + P+F D + +A +G+ L+ A L + S+++ +C K +VT + Sbjct: 243 LVTQRVMDQRILEELYNFKHVIEELTRELCLVRAHDVKLTKETEKAHKDLAQALLNAEKNAKIVEEYHDLYTLQRERMENDMKKLVAERDIWSSATYELALKVIERNRVILARRLYLNEKGWNKYTKHFIILLSNKDTEDLALLQKLTQKWRNLVNKLKQEVEQMEESTSETLKIVKDGLIKWQEFFNEKDILSPN-----------KGNIFNSVLLDFKQWQKILNEKKEEFTGDVLLSKYDTLKIIKHLQENWADIGLGIFNRHKS-LEGEMPSERQYMEEIIKNIQKLYKEYEIRINGDNGYSKILPSLISSLDFCSFKLEN----LEFPDTPLEEWQEIDEKINEMKSHLDILLNLTGIVP-QHIDVDSVSV---LQAY-IFNMIQQWLLKIGNEINNGNIELQHHMDELHISMIQWMVNLLILMIPNFTDQDCLLKLEEESAEKHDIGVARLELDAIELTRKLYQYSSYLSSCCKGMVTAM 707 HSP 2 Score: 106.301 bits (264), Expect = 3.251e-59 Identity = 66/211 (31.28%), Postives = 116/211 (54.98%), Query Frame = 1 Query: 244 VSNVWSSVIRREKFKHISDNPICICGAGNDLTFLYD--KLPNEIIEHFSDPLINXXXXXXXXXXIEDKMLMRLPEKLDPAEFTLSTHQGMREIQLYDESFTTKPFPHKYHKXXXXXXXXXXXXXXXKIYQSFGDVLDKSGLNEPFEFNMPTVLHNLLMTVKKEQDLYNVVFHEVIKETTIDCIERGELLANIRQRYRNLFFKIPEKIKEFH 870 V +VW +RR KFK++ D+P+ + GAG D++FLYD + E P + + I L + L P EF + + G+ ++ YD+ +TT + + P M PN ++ +L+++G+ E E+ PT +H LL +KKEQ +YN++FHE+I++ ++DC +RGELL+ +R+RY + +I ++ +F+ Sbjct: 31 VDHVWHHPVRRNKFKYLIDHPVSLTGAGRDISFLYDVTYAKGQTREKAVCPPHLARSLQSHDGVIVPHKPKTLTDTLIPEEFHIVSSTGVSGLECYDDKYTTLLTDSENRLLLFPSMKPNKRVEVAQLNDVMDTMLERAGV-ENQEYTGPTKMHKLLHILKKEQTIYNMIFHELIRQVSVDCADRGELLSKVRERYVQMLDQIARQMIDFY 240
BLAST of Sterol O-acyltransferase 1 vs. Ensembl Human
Match: AXDND1 (axonemal dynein light chain domain containing 1 [Source:HGNC Symbol;Acc:HGNC:26564]) HSP 1 Score: 113.235 bits (282), Expect = 2.508e-43 Identity = 83/274 (30.29%), Postives = 139/274 (50.73%), Query Frame = 1 Query: 103 LPLLKFKENYSTHSKPAVKPIP-AFLSDEILTNLQQCTNALVCPH-----------EGK----VSNVWSSVIRREKFKHISDNPICICGAGNDLTFLYD--KLPNEIIEHFSDPLINXXXXXXXXXXIEDKMLMRLPEKLDPAEFTLSTHQGMREIQLYDESFTTKPFPHKYHKXXXXXXXXXXXXXXXKIYQSFGDVLDKSGLNEPFEFNMPTVLHNLLMTVKKEQDLYNVVFHEVIKETTIDCIERGELLANIRQRYRNLFFKIPEKIKEFH 870 LP LK K+N SK + F+ E+L +L NA CP +G V +VW +RR KFK++ D+P+ + GAG D++FLYD + E P + + I L + L P EF + + G+ ++ YD+ +TT + + P M PN ++ +L+++G+ E E+ PT +H LL +KKEQ +YN++FHE+I++ ++DC +RGELL+ +R+RY + +I ++ +F+ Sbjct: 34 LPELKEKKNMVDRSKLLPTSLQNEFIPKEVLLSLTYAANAGPCPENLLPPKKIKTPKGTLPRLVDHVWHHPVRRNKFKYLIDHPVSLTGAGRDISFLYDVTYAKGQTREKAVCPPHLARSLQSHDGVIVPHKPKTLTDTLIPEEFHIVSSTGVSGLECYDDKYTTLLTDSENRLLLFPSMKPNKRVEVAQLNDVMDTMLERAGV-ENQEYTGPTKMHKLLHILKKEQTIYNMIFHELIRQVSVDCADRGELLSKVRERYVQMLDQIARQMIDFY 306 HSP 2 Score: 84.7297 bits (208), Expect = 2.508e-43 Identity = 48/158 (30.38%), Postives = 91/158 (57.59%), Query Frame = 3 Query: 876 VVARKILDRRLTEELLRFQNTVSMLSKELSGVKDHEENINQICKQAKLQLKEAVEETKTNADLLREYHDLYEQQRQRLERNVLQLERERDCWRNAAYKITQLVLEHYEIKPAIVLVECESNMISLSQYFVELISVTDNQTLSTIKTKTTQWCNEAQKF 1349 +V ++++D+R+ EEL F++ + L++EL V+ H+ + + ++A L +A+ + NA ++ EYHDLY QR+R+E ++ +L ERD W +A Y++ V+E + A L E +++F+ L+S D + L+ ++ T +W N K Sbjct: 309 LVTQRVMDQRILEELYNFKHVIEELTRELCLVRAHDVKLTKETEKAHKDLAQALLNAEKNAKIVEEYHDLYTLQRERMENDMKKLVAERDIWSSATYELALKVIERNRVILARRLYLNEKGWNKYTKHFIILLSNKDTEDLALLQKLTQKWRNLVNKL 466
BLAST of Sterol O-acyltransferase 1 vs. Ensembl Human
Match: AXDND1 (axonemal dynein light chain domain containing 1 [Source:HGNC Symbol;Acc:HGNC:26564]) HSP 1 Score: 113.235 bits (282), Expect = 2.508e-43 Identity = 83/274 (30.29%), Postives = 139/274 (50.73%), Query Frame = 1 Query: 103 LPLLKFKENYSTHSKPAVKPIP-AFLSDEILTNLQQCTNALVCPH-----------EGK----VSNVWSSVIRREKFKHISDNPICICGAGNDLTFLYD--KLPNEIIEHFSDPLINXXXXXXXXXXIEDKMLMRLPEKLDPAEFTLSTHQGMREIQLYDESFTTKPFPHKYHKXXXXXXXXXXXXXXXKIYQSFGDVLDKSGLNEPFEFNMPTVLHNLLMTVKKEQDLYNVVFHEVIKETTIDCIERGELLANIRQRYRNLFFKIPEKIKEFH 870 LP LK K+N SK + F+ E+L +L NA CP +G V +VW +RR KFK++ D+P+ + GAG D++FLYD + E P + + I L + L P EF + + G+ ++ YD+ +TT + + P M PN ++ +L+++G+ E E+ PT +H LL +KKEQ +YN++FHE+I++ ++DC +RGELL+ +R+RY + +I ++ +F+ Sbjct: 34 LPELKEKKNMVDRSKLLPTSLQNEFIPKEVLLSLTYAANAGPCPENLLPPKKIKTPKGTLPRLVDHVWHHPVRRNKFKYLIDHPVSLTGAGRDISFLYDVTYAKGQTREKAVCPPHLARSLQSHDGVIVPHKPKTLTDTLIPEEFHIVSSTGVSGLECYDDKYTTLLTDSENRLLLFPSMKPNKRVEVAQLNDVMDTMLERAGV-ENQEYTGPTKMHKLLHILKKEQTIYNMIFHELIRQVSVDCADRGELLSKVRERYVQMLDQIARQMIDFY 306 HSP 2 Score: 84.7297 bits (208), Expect = 2.508e-43 Identity = 48/158 (30.38%), Postives = 91/158 (57.59%), Query Frame = 3 Query: 876 VVARKILDRRLTEELLRFQNTVSMLSKELSGVKDHEENINQICKQAKLQLKEAVEETKTNADLLREYHDLYEQQRQRLERNVLQLERERDCWRNAAYKITQLVLEHYEIKPAIVLVECESNMISLSQYFVELISVTDNQTLSTIKTKTTQWCNEAQKF 1349 +V ++++D+R+ EEL F++ + L++EL V+ H+ + + ++A L +A+ + NA ++ EYHDLY QR+R+E ++ +L ERD W +A Y++ V+E + A L E +++F+ L+S D + L+ ++ T +W N K Sbjct: 309 LVTQRVMDQRILEELYNFKHVIEELTRELCLVRAHDVKLTKETEKAHKDLAQALLNAEKNAKIVEEYHDLYTLQRERMENDMKKLVAERDIWSSATYELALKVIERNRVILARRLYLNEKGWNKYTKHFIILLSNKDTEDLALLQKLTQKWRNLVNKL 466
BLAST of Sterol O-acyltransferase 1 vs. Ensembl Human
Match: AXDND1 (axonemal dynein light chain domain containing 1 [Source:HGNC Symbol;Acc:HGNC:26564]) HSP 1 Score: 53.5286 bits (127), Expect = 8.754e-8 Identity = 27/75 (36.00%), Postives = 40/75 (53.33%), Query Frame = 1 Query: 172 FLSDEILTNLQQCTNALVCPH-----------EGK----VSNVWSSVIRREKFKHISDNPICICGAGNDLTFLYD 351 F+ E+L +L NA CP +G V +VW +RR KFK++ D+P+ + GAG D++FLYD Sbjct: 16 FIPKEVLLSLTYAANAGPCPENLLPPKKIKTPKGTLPRLVDHVWHHPVRRNKFKYLIDHPVSLTGAGRDISFLYD 90
BLAST of Sterol O-acyltransferase 1 vs. Ensembl Zebrafish
Match: axdnd1 (axonemal dynein light chain domain containing 1 [Source:ZFIN;Acc:ZDB-GENE-050208-341]) HSP 1 Score: 160.614 bits (405), Expect = 2.094e-65 Identity = 176/763 (23.07%), Postives = 363/763 (47.58%), Query Frame = 3 Query: 876 VVARKILDRRLTEELLRFQNTVSMLSKELSGVKDHEENINQICKQAKLQLKEAVEETKTNADLLREYHDLYEQQRQRLERNVLQLERERDCWRNAAYKITQLVLEHYEIKPAIVLVECESNMISLSQYFVELISVTDNQTLSTIKTKTTQWCNEAQKFALMLAIREENLKTLLNKEIEK-INRLKEDFEDDYLSEQGQLIQPINQEETRKILNSVINWEKSMSEICESFGGQSMLMEEEKLKHMKQLCYEYTDIAVEVFNRHRNETDGSLYQEHSALLDINKLIDEMMTQFMDQLTGDNGVADGIIALQTFEENW---ITRLSNSVAELYFRPLPDSEWIRFKLLLDDWIALLCESKNAIGTTKLNSITVEGASI-NKRLEIHEIIQSVDNWSQKSSSGIESENLKLREAIINLKKSMIRWTSQVILRLAPDFPDNSPEARRAARL---ASLGIRELQETAKVLHENISAVSNHIFNCSKDIVTKLMQIKIDTQTEFPDGDSLKLHQLIEFSKSWIEKSEQLLKEI----MELEYETQNKMRSEKDTEEMPFVKENSTIDKEKRIEENEIEDYDAGALIGNLLDNVINATSDLFLPEDDNDEDDKIMEVPIPPPTVEGIGVDYNVHSKMLIQDPNEPYSRNKFRNTEPINMPNDLPKTEEAYLLIKIFENLQKRLRSLTVEAMTVEDQCAKKELENEKSKRYLKSLEEIYEKRIIELEQLQTEKKQTLPTPALFNGTSAMERHLSESTNRSTTPKSVTSSKRR 3128 +A++ LDRRLTEE+L F+N+++ L+ ELS +K H+EN+++ ++AK +L +A+EE++ NA+++ EYH+LYE QR+RLE + L+ ERD WR A Y + +++ ++ L E + F ++ D++ S I T +W + F L IR EN + + K I + ++ FE+ + +++ ++ + W K +++ CE +GG+ ++ +E L+ +K+L + ++ +++F RH DG + A+ + + I E ++Q ++ G++G+ ++ L E+W + LS E +W++ K L + L E+ + +T+ S G +I + ++E+ ++++++ + + + EN++LR+ + +L MI W ++L + P D+ A L ++ + +L+E A+ + + S +I + + I+ ++ I+ + + + + +L +L + W+E LL ++ EL+ + RS K+ E KE ++ +E E+ AG +D+D ++++ IG D N+ K L +D + + TE + + K ++A+ ++ LQ+ L ++ A+ E + K E E + + ++ LE + R + ++ KK TP+ TS + ++S N ++PK +K+R Sbjct: 300 TLAQRALDRRLTEEILHFKNSIASLNMELSAMKVHDENVSKEAEEAKEELAKALEESQRNANIVAEYHELYELQRKRLEGQMSHLDGERDLWRKATYSLAVKIIKINKLHLVRRLHISEQTWAKAADRFTFFLTAKDSEYFSHIMDLTNRWKDTLANFMQNL-IRVENKQREIIKSFHSNIVKWQKFFEE----KSRHPTMKVDKSSDEELSQDLREWSKVLTQQCERYGGEDLVSGQETLELLKKLQESWIEVCLDLFKRHTG-PDGGPPKGQEAMRGLKRTITEFLSQLGIRINGESGIHAMLMFLIDTMESWSRILNPLSGPPKEQAL-----GDWLKLKEALGSLVNLSEEALLLVDSTQ--SEQDRGKNIPHIKIEMEDVLKTMKEFLFSQENFFDCENMRLRDEVTSLHNKMIHWMVDLLLLMVPIHSDDQEPFLPAPELNIVVNVSVEKLEEDARNISTKLDYFSKYITSSCQAIIEEV--IRKSSNQDETENELYELAKLQKECGEWLEACRLLLMDVKGSSAELKLNGKVVPRSPKEQSEEHTEKEEPLDLEDANEPYDEYEEEKAGK----------------------HDKDGSVIKL---------IGHDGNITEKTLREDTVQ------LKGTEELVITPHTEKAQDAFSSLETIRTLQQELLAVETRAINSEVRALKAEEELQAALDKIQDLERQLQAR--PSVETKSSKKNAPKTPSKPVATSEAK---TKSQNPESSPKLSRGTKKR 1005 HSP 2 Score: 110.538 bits (275), Expect = 2.094e-65 Identity = 67/214 (31.31%), Postives = 118/214 (55.14%), Query Frame = 1 Query: 253 VWSSVIRREKFKHISDNPICICGAGNDLTFLYDKLPNEIIEHFSDPLINXXXXXXXXXXIEDKMLMRLPEKLDPAEFTLSTHQGMREIQLYDESFTTKPFPHKYHKXXXXXXXXXXXXXXXKIYQSFGDVLDKSGLNEPF-EFNMPTVLHNLLMTVKKEQDLYNVVFHEVIKETTIDCIERGELLANIRQRYRNLFFKIPEKIKEFHDK*LHEK 891 VW +RR+K+++ + P + GAG D++FL D L ++ P+ N + + L E L P E+ + ++G++ +Q YD+ FT K P M P+ ++ + +L+K+G+NE F E + + NLL ++ EQ++YN+VFHEVI++ +++C ERG+LLA +RQ+Y L +IP ++K H + L ++ Sbjct: 95 VWHHPVRRKKYQYFLNQPTSLTGAGRDISFLCDCLGSQKDALPVIPMANRRSALHHGDHNDTNPL----ETLIPEEYHIIKNKGLKGLQCYDDKFTVLLEDEKNKLRVFPSMKPSGRLEVVQLMKVMDKMLEKAGVNEEFQELTEISQIENLLELIQTEQNIYNIVFHEVIRQVSVECAERGQLLAKLRQKYVALLDRIPRQVKGLHTQTLAQR 304
BLAST of Sterol O-acyltransferase 1 vs. Ensembl Xenopus
Match: wsb1 (WD repeat and SOCS box containing 1 [Source:Xenbase;Acc:XB-GENE-5920309]) HSP 1 Score: 124.02 bits (310), Expect = 5.489e-56 Identity = 78/299 (26.09%), Postives = 162/299 (54.18%), Query Frame = 3 Query: 876 VVARKILDRRLTEELLRFQNTVSMLSKELSGVKDHEENINQICKQAKLQLKEAVEETKTNADLLREYHDLYEQQRQRLERNVLQLERERDCWRNAAYKITQLVLEHYEIKPAIVLVECESNMISLSQYFVELISVTDNQTLSTIKTKTTQWCNEAQKFALMLAIREENLKTLLNKEIEKINRLKEDFEDDYLSEQGQLIQPINQEETRKILNSVINWEKSMSEICESFGGQSMLMEEEKLKHMKQLCYEYTDIAVEVFNRHRNETDGSLYQEHSALLDINKLIDEMMTQFMDQLTGDNG 1772 ++A++ LDR LT+E++ F+N++ ++ EL V++H+ +++ QA +L +A+ E K NA++L EY +LYE QR RLE++++ L ERD W +A Y I V+E ++ A L CE ++ ++F+ +++ T + L I+ T W F + EE+ + + +++ ++ F+++ + + I ++ + + W+ ++E + F G +L +E L + ++T++ ++ RH++ +D L E AL+D+ I ++ Q+ ++ G+NG Sbjct: 293 LLAQRALDRCLTKEIMNFKNSIEDMTNELYQVREHDLRVSRDANQAHAELAKALSEAKKNANILDEYRELYELQRSRLEKHLVDLTEERDLWSSATYMIASKVIERNQLHLARKLCMCEKTWTNIIRHFIVMLASTSAKDLIQIQQITESWRGHMAHFDQDVQRNEESNREKMRLIQNDLDKWQQHFQENVFVHER--FEEIREDVIESVSQDLRKWDSMLNEELQQFEGCQLLSYQESLSTALDIQKQWTELGEKLLRRHQS-SDKDLPPEEKALVDMKGKIQQLCEQYRRRIEGENG 588 HSP 2 Score: 116.316 bits (290), Expect = 5.489e-56 Identity = 78/253 (30.83%), Postives = 135/253 (53.36%), Query Frame = 1 Query: 136 THSKPAVKPIPAFLSDEILTNLQQCTNA-----LVCPHEGKV-----SNVWSSVIRREKFKHISDNPICICGAGNDLTFLYDKLPNEIIEHFSDPL--INXXXXXXXXXXIEDKMLMRLPEKLDPAEFTLSTHQGMREIQLYDESFTTKPFPHKYHKXXXXXXXXXXXXXXXKIYQSFGDVLDKSGLNEPFEFNMPTVLHNLLMTVKKEQDLYNVVFHEVIKETTIDCIERGELLANIRQRYRNLFFKIPEKI 858 THS + ++ +EIL L T+A L + KV N W +RR KF H+ + P+C+ GAG D++FL D + ++ L I+ + + + I+ E L P E+ + ++G+ ++ +++ +TT + P + P+ S ++ + +L +G++E + PT +HNLL +K EQ++YN+VFHEVI++ +++C+ERGELLA +RQRY LF KIP ++ Sbjct: 43 THS-GTISQHKDYIPEEILQILTSATSASHKLDLETRKDAKVCLRSTDNAWHHQLRRSKFNHLIEQPVCLKGAGRDISFLCDVILSDKRNRSVTSLQPISHKNDTSKEEGIQ--------ESLVPEEYYIVKNKGILGLEYHEDKYTTLLKDDEKKLRLFPSLKPSGRSEVLQLIKVMDSMLKDAGVDEDLKLEGPTPIHNLLELLKAEQNIYNIVFHEVIRQVSVECVERGELLAKLRQRYAMLFDKIPRQV 286
BLAST of Sterol O-acyltransferase 1 vs. Ensembl Xenopus
Match: wsb1 (WD repeat and SOCS box containing 1 [Source:Xenbase;Acc:XB-GENE-5920309]) HSP 1 Score: 88.5817 bits (218), Expect = 6.437e-36 Identity = 38/84 (45.24%), Postives = 61/84 (72.62%), Query Frame = 1 Query: 640 VLDKSGLNEPFEFNMPTVLHNLLMTVKKEQDLYNVVFHEVIKETTIDCIERGELLANIRQRYRNLFFKIPEKIKEFHDK*LHEK 891 +L +G++E + PT +HNLL +K EQ++YN+VFHEVI++ +++C+ERGELLA +RQRY LF KIP ++ ++ L ++ Sbjct: 31 MLKDAGVDEDLKLEGPTPIHNLLELLKAEQNIYNIVFHEVIRQVSVECVERGELLAKLRQRYAMLFDKIPRQVLSLYNDLLAQR 114 HSP 2 Score: 84.7297 bits (208), Expect = 6.437e-36 Identity = 74/299 (24.75%), Postives = 139/299 (46.49%), Query Frame = 3 Query: 876 VVARKILDRRLTEELLRFQNTVSMLSKELSGVKDHEENINQICKQAKLQLKEAVEETKTNADLLREYHDLYEQQRQRLERNVLQLERERDCWRNAAYKITQLVLEHYEIKPAIVLVECESNMISLSQYFVELISVTDNQTLSTIKTKTTQWCNEAQKFALMLAIREENLKTLLNKEIEKINRLKEDFEDDYLSEQGQLIQPINQEETRKILNSVINWEKSMSEICESFGGQSMLMEEEKLKHMKQLCYEYTDIAVEVFNRHRNETDGSLYQEHSALLDINKLIDEMMTQFMDQLTGDNG 1772 ++A++ LDR LT+E++ F+N++ ++ EL V++H+ +++ QA +L +A+ E K NA++L EY +LYE QR RLE++++ L ERD W +A Y +I+ + L I+ T W F + EE+ + EK+ ++ D + Q QE + + ++N E E C+ +L +E L + ++T++ ++ RH++ +D L E AL+D+ I ++ Q+ ++ G+NG Sbjct: 110 LLAQRALDRCLTKEIMNFKNSIEDMTNELYQVREHDLRVSRDANQAHAELAKALSEAKKNANILDEYRELYELQRSRLEKHLVDLTEERDLWSSATY----------------------------------MIASKSAKDLIQIQQITESWRGHMAHFDQDVQRNEESNR-------EKMRLIQNDLDK---------WQQHFQENSAGVCYIMLNEELQQFEGCQ------LLSYQESLSTALDIQKQWTELGEKLLRRHQS-SDKDLPPEEKALVDMKGKIQQLCEQYRRRIEGENG 351
BLAST of Sterol O-acyltransferase 1 vs. Ensembl Mouse
Match: Axdnd1 (axonemal dynein light chain domain containing 1 [Source:MGI Symbol;Acc:MGI:1924602]) HSP 1 Score: 151.754 bits (382), Expect = 4.319e-65 Identity = 136/552 (24.64%), Postives = 258/552 (46.74%), Query Frame = 3 Query: 876 VVARKILDRRLTEELLRFQNTVSMLSKELSGVKDHEENINQICKQAKLQLKEAVEETKTNADLLREYHDLYEQQRQRLERNVLQLERERDCWRNAAYKITQLVLEHYEIKPAIVLVECESNMISLSQYFVELISVTDNQTLSTIKTKTTQWCNEAQKFALMLAIREENLKTLLNKEIEKINRLK-EDFEDDYLSEQGQLIQPINQEETRKILNSVINWEKSMSEICESFGGQSMLMEEEKLKHMKQLCYEYTDIAVEVFNRHRNETDGSLYQEHSALLDINKLIDEMMTQFMDQLTGDNGVADGIIALQTFEENWITRLSNSVAELYFRPLPDSEWIRFKLLLDDWIALLCESKNAIGTTKLNSITVEGASINKRLEIHEIIQSVDNWSQKSSSGIESENLKLREAIINLKKSMIRWTSQVILRLAPDFPDNSPEARR------AARLASLGIRELQETAKVLHENISAVSNHIFNCSKDIVTKLMQIKIDTQTEFPDGDSLKLHQLIEFSKSWIEKSEQLLKEIME-----LEYETQNKMRSEKDTEEMPF 2495 +V ++++D+R+ +EL F+N + L++EL V+ H+ + + ++ + L EA+ E + NA ++ +YHDLY QR R+E ++ L ERD W +A Y++ V+E + A L E +++F+ ++S D L ++ T +W KF + EE+ K EI K +K ++F ++ L + +I P + LN +EK + E E F G +L + LK +K+L +TDI + +RH++ DG L EH + DI K+I ++ ++ ++ GDNG++ + L + + +L N L + +P EW+ +++ L N I + GA++ + I + + W K + I + ++L + + +MI+W ++ + PDF D +R +GI EL+ A L + ++ S+++ +C +V + + + P D L ++ WI L+ +I L YE K+ E++ ++ F Sbjct: 306 LVTQRMMDQRILQELYNFKNVIEELTRELCLVQAHDRKLTKEAEKVQKNLAEALLEAEKNAKIVEDYHDLYTMQRGRMESDIKLLMTERDIWSSATYELALKVIERNRVILAKKLYLSEKGWNKYAKHFIIMLSTKDTGDLGMVEKLTEKWKKLVNKFKQDVERTEESTKE--KSEIVKAGIIKWQEFFNNNLGK--DVIIPSKRSPFAVALNDFKEYEKMLEEEKEKFTGDFLLSRYDALKVIKRLQENWTDIGFGILSRHKS-MDGLLPPEHEYMEDIVKIISKLYREYEIRINGDNGISKVLPNLVISLDMCVFKLENF---LDYSQVPTEEWLEIDEKINEMKFHLEALLNIIDSVPEGMDMEPGAAL-----LEHICEMIQQWLLKLGNEITNGQIELLRHMDEMHIAMIQWMVNLLTIMLPDFTDQDILPKREESSLETPEEHEIGIAELEINAIALVKRLARYSSYLHSCCIGMVRAMALSRAAHLQKNPAKDRQDLERMNRECYDWISTCSHLISDIKGRKIRLLSYEEAEKLLGEEEASKLYF 844 HSP 2 Score: 118.627 bits (296), Expect = 4.319e-65 Identity = 87/278 (31.29%), Postives = 144/278 (51.80%), Query Frame = 1 Query: 103 LPLLKFKENYSTHSKPAVKPIPAFLSD-----EILTNLQQCTNALVCPHE---------------GKVSNVWSSVIRREKFKHISDNPICICGAGNDLTFLYD--KLPNEIIEHFSDPLINXXXXXXXXXXIEDKMLMRLPEKLDPAEFTLSTHQGMREIQLYDESFTTKPFPHKYHKXXXXXXXXXXXXXXXKIYQSFGDVLDKSGLNEPFEFNMPTVLHNLLMTVKKEQDLYNVVFHEVIKETTIDCIERGELLANIRQRYRNLFFKIPEKIKEFH 870 LP LK K++ H +KP+P +D E+L +L NA CP V +VW IRR+KFK++ D+P+ + GAG D++FLYD + E +E P N + S + K L + L P EF + ++ G+ ++ YD+ +TT + + P M PN ++ +L+++G+ E + PT +H LL +K+EQ +YN VFHE+I++ ++DC +RGELL+ IR++Y + I +++ EF+ Sbjct: 33 LPELKEKKSMVNH----LKPLPPLQNDYRIPEEVLLSLNYAANAGPCPESLLPVKKPKAPKCALPRLVDHVWQHPIRRDKFKYLIDHPVSLTGAGRDISFLYDVKYVKGEAVEKKLCP-PNKSTQSQSSAMVPHKE-KTLADTLVPEEFHIVSNTGVSGLECYDDKYTTLLTDSENRLLLFPSMKPNKRVEVVQLSNVMDTMLERAGI-ENENYVGPTKMHQLLNVLKREQSIYNTVFHELIRQVSVDCADRGELLSKIREKYVQMLDHIAQQMIEFY 303
BLAST of Sterol O-acyltransferase 1 vs. Ensembl Mouse
Match: Axdnd1 (axonemal dynein light chain domain containing 1 [Source:MGI Symbol;Acc:MGI:1924602]) HSP 1 Score: 149.058 bits (375), Expect = 2.446e-64 Identity = 135/544 (24.82%), Postives = 254/544 (46.69%), Query Frame = 3 Query: 876 VVARKILDRRLTEELLRFQNTVSMLSKELSGVKDHEENINQICKQAKLQLKEAVEETKTNADLLREYHDLYEQQRQRLERNVLQLERERDCWRNAAYKITQLVLEHYEIKPAIVLVECESNMISLSQYFVELISVTDNQTLSTIKTKTTQWCNEAQKFALMLAIREENLKTLLNKEIEKINRLK-EDFEDDYLSEQGQLIQPINQEETRKILNSVINWEKSMSEICESFGGQSMLMEEEKLKHMKQLCYEYTDIAVEVFNRHRNETDGSLYQEHSALLDINKLIDEMMTQFMDQLTGDNGVADGIIALQTFEENWITRLSNSVAELYFRPLPDSEWIRFKLLLDDWIALLCESKNAIGTTKLNSITVEGASINKRLEIHEIIQSVDNWSQKSSSGIESENLKLREAIINLKKSMIRWTSQVILRLAPDFPDNSPEARR------AARLASLGIRELQETAKVLHENISAVSNHIFNCSKDIVTKLMQIKIDTQTEFPDGDSLKLHQLIEFSKSWIEKSEQLL-----KEIMELEYETQNKMRSE 2471 +V ++++D+R+ +EL F+N + L++EL V+ H+ + + ++ + L EA+ E + NA ++ +YHDLY QR R+E ++ L ERD W +A Y++ V+E + A L E +++F+ ++S D L ++ T +W KF + EE+ K EI K +K ++F ++ L + +I P + LN +EK + E E F G +L + LK +K+L +TDI + +RH++ DG L EH + DI K+I ++ ++ ++ GDNG++ + L + + +L N L + +P EW+ +++ L N I + GA++ + I + + W K + I + ++L + + +MI+W ++ + PDF D +R +GI EL+ A L + ++ S+++ +C +V + + + P D L ++ WI L+ ++I L YE K+ E Sbjct: 306 LVTQRMMDQRILQELYNFKNVIEELTRELCLVQAHDRKLTKEAEKVQKNLAEALLEAEKNAKIVEDYHDLYTMQRGRMESDIKLLMTERDIWSSATYELALKVIERNRVILAKKLYLSEKGWNKYAKHFIIMLSTKDTGDLGMVEKLTEKWKKLVNKFKQDVERTEESTKE--KSEIVKAGIIKWQEFFNNNLGK--DVIIPSKRSPFAVALNDFKEYEKMLEEEKEKFTGDFLLSRYDALKVIKRLQENWTDIGFGILSRHKS-MDGLLPPEHEYMEDIVKIISKLYREYEIRINGDNGISKVLPNLVISLDMCVFKLENF---LDYSQVPTEEWLEIDEKINEMKFHLEALLNIIDSVPEGMDMEPGAAL-----LEHICEMIQQWLLKLGNEITNGQIELLRHMDEMHIAMIQWMVNLLTIMLPDFTDQDILPKREESSLETPEEHEIGIAELEINAIALVKRLARYSSYLHSCCIGMVRAMALSRAAHLQKNPAKDRQDLERMNRECYDWISTCSHLISDIKGRKIRLLSYEEAEKLLGE 836 HSP 2 Score: 118.627 bits (296), Expect = 2.446e-64 Identity = 87/278 (31.29%), Postives = 144/278 (51.80%), Query Frame = 1 Query: 103 LPLLKFKENYSTHSKPAVKPIPAFLSD-----EILTNLQQCTNALVCPHE---------------GKVSNVWSSVIRREKFKHISDNPICICGAGNDLTFLYD--KLPNEIIEHFSDPLINXXXXXXXXXXIEDKMLMRLPEKLDPAEFTLSTHQGMREIQLYDESFTTKPFPHKYHKXXXXXXXXXXXXXXXKIYQSFGDVLDKSGLNEPFEFNMPTVLHNLLMTVKKEQDLYNVVFHEVIKETTIDCIERGELLANIRQRYRNLFFKIPEKIKEFH 870 LP LK K++ H +KP+P +D E+L +L NA CP V +VW IRR+KFK++ D+P+ + GAG D++FLYD + E +E P N + S + K L + L P EF + ++ G+ ++ YD+ +TT + + P M PN ++ +L+++G+ E + PT +H LL +K+EQ +YN VFHE+I++ ++DC +RGELL+ IR++Y + I +++ EF+ Sbjct: 33 LPELKEKKSMVNH----LKPLPPLQNDYRIPEEVLLSLNYAANAGPCPESLLPVKKPKAPKCALPRLVDHVWQHPIRRDKFKYLIDHPVSLTGAGRDISFLYDVKYVKGEAVEKKLCP-PNKSTQSQSSAMVPHKE-KTLADTLVPEEFHIVSNTGVSGLECYDDKYTTLLTDSENRLLLFPSMKPNKRVEVVQLSNVMDTMLERAGI-ENENYVGPTKMHQLLNVLKREQSIYNTVFHELIRQVSVDCADRGELLSKIREKYVQMLDHIAQQMIEFY 303
BLAST of Sterol O-acyltransferase 1 vs. Ensembl Mouse
Match: Axdnd1 (axonemal dynein light chain domain containing 1 [Source:MGI Symbol;Acc:MGI:1924602]) HSP 1 Score: 144.436 bits (363), Expect = 2.094e-60 Identity = 131/524 (25.00%), Postives = 250/524 (47.71%), Query Frame = 3 Query: 876 VVARKILDRRLTEELLRFQNTVSMLSKELSGVKDHEENINQICKQAKLQLKEAVEETKTNADLLREYHDLYEQQRQRLERNVLQLERERDCWRNAAYKITQLVLEHYEIKPAIVLVECESNMISLSQYFVELISVTDNQTLSTIKTKTTQWCNEAQKFALMLAIREENLKTLLNKEIEKINRLK-EDFEDDYLSEQGQLIQPINQEETRKILNSVINWEKSMSEICESFGGQSMLMEEEKLKHMKQLCYEYTDIAVEVFNRHRNETDGSLYQEHSALLDINKLIDEMMTQFMDQLTGDNGVADGIIALQTFEENWITRLSNSVAELYFRPLPDSEWIRFKLLLDDWIALLCESKNAIGTTKLNSITVEGASINKRLEIHEIIQSVDNWSQKSSSGIESENLKLREAIINLKKSMIRWTSQVILRLAPDFPDNSPEARR------AARLASLGIRELQETAKVLHENISAVSNHIFNCSKDIVTKLMQIKIDTQTEFPDGDSLKLHQLIEFSKSWIEKSEQLLKE 2426 +V ++++D+R+ +EL F+N + L++EL V+ H+ + + ++ + L EA+ E + NA ++ +YHDLY QR R+E ++ L ERD W +A Y++ V+E + A L E +++F+ ++S D L ++ T +W KF + EE+ K EI K +K ++F ++ L + +I P + LN +EK + E E F G +L + LK +K+L +TDI + +RH++ DG L EH + DI K+I ++ ++ ++ GDNG++ + L + + +L N L + +P EW+ +++ L N I + GA++ + I + + W K + I + ++L + + +MI+W ++ + PDF D +R +GI EL+ A L + ++ S+++ +C +V + + + P D L ++ S S EK+ + +K+ Sbjct: 241 LVTQRMMDQRILQELYNFKNVIEELTRELCLVQAHDRKLTKEAEKVQKNLAEALLEAEKNAKIVEDYHDLYTMQRGRMESDIKLLMTERDIWSSATYELALKVIERNRVILAKKLYLSEKGWNKYAKHFIIMLSTKDTGDLGMVEKLTEKWKKLVNKFKQDVERTEESTKE--KSEIVKAGIIKWQEFFNNNLGK--DVIIPSKRSPFAVALNDFKEYEKMLEEEKEKFTGDFLLSRYDALKVIKRLQENWTDIGFGILSRHKS-MDGLLPPEHEYMEDIVKIISKLYREYEIRINGDNGISKVLPNLVISLDMCVFKLENF---LDYSQVPTEEWLEIDEKINEMKFHLEALLNIIDSVPEGMDMEPGAAL-----LEHICEMIQQWLLKLGNEITNGQIELLRHMDEMHIAMIQWMVNLLTIMLPDFTDQDILPKREESSLETPEEHEIGIAELEINAIALVKRLARYSSYLHSCCIGMVRAMALSRAAHLQKNPAKDRQDLERMNGPSPSTNEKTIRYIKK 751 HSP 2 Score: 110.153 bits (274), Expect = 2.094e-60 Identity = 70/211 (33.18%), Postives = 120/211 (56.87%), Query Frame = 1 Query: 244 VSNVWSSVIRREKFKHISDNPICICGAGNDLTFLYD--KLPNEIIEHFSDPLINXXXXXXXXXXIEDKMLMRLPEKLDPAEFTLSTHQGMREIQLYDESFTTKPFPHKYHKXXXXXXXXXXXXXXXKIYQSFGDVLDKSGLNEPFEFNMPTVLHNLLMTVKKEQDLYNVVFHEVIKETTIDCIERGELLANIRQRYRNLFFKIPEKIKEFH 870 V +VW IRR+KFK++ D+P+ + GAG D++FLYD + E +E P N + S + K L + L P EF + ++ G+ ++ YD+ +TT + + P M PN ++ +L+++G+ E + PT +H LL +K+EQ +YN VFHE+I++ ++DC +RGELL+ IR++Y + I +++ EF+ Sbjct: 31 VDHVWQHPIRRDKFKYLIDHPVSLTGAGRDISFLYDVKYVKGEAVEKKLCP-PNKSTQSQSSAMVPHKE-KTLADTLVPEEFHIVSNTGVSGLECYDDKYTTLLTDSENRLLLFPSMKPNKRVEVVQLSNVMDTMLERAGI-ENENYVGPTKMHQLLNVLKREQSIYNTVFHELIRQVSVDCADRGELLSKIREKYVQMLDHIAQQMIEFY 238
BLAST of Sterol O-acyltransferase 1 vs. Ensembl Mouse
Match: Axdnd1 (axonemal dynein light chain domain containing 1 [Source:MGI Symbol;Acc:MGI:1924602]) HSP 1 Score: 105.145 bits (261), Expect = 5.114e-23 Identity = 89/337 (26.41%), Postives = 162/337 (48.07%), Query Frame = 3 Query: 876 VVARKILDRRLTEELLRFQNTVSMLSKELSGVKDHEENINQICKQAKLQLKEAVEETKTNADLLREYHDLYEQQRQRLERNVLQLERERDCWRNAAYKITQLVLEHYEIKPAIVLVECESNMISLSQYFVELISVTDNQTLSTIKTKTTQWCNEAQKFALMLAIREENLKTLLNKEIEKINRLK-EDFEDDYLSEQGQLIQPINQEETRKILNSVINWEKSMSEICESFGGQSMLMEEEKLKHMKQLCYEYTDIAVEVFNRHRNETDGSLYQEHSALLDINKLIDEMMTQFMDQLTGDNGVADGIIALQTFEENWITRLSNSVAELYFRPLPDSEWI 1883 +V ++++D+R+ +EL F+N + L++EL V+ H+ + + ++ + L EA+ E + NA ++ +YHDLY QR R+E ++ L ERD W +A Y++ ++ D L ++ T +W KF + EE+ K EI K +K ++F ++ L + +I P + LN +EK + E E F G +L + LK +K+L +TDI + +RH++ DG L EH + DI K+I ++ ++ ++ GDNG++ + L + + +L N L + +P EW+ Sbjct: 144 LVTQRMMDQRILQELYNFKNVIEELTRELCLVQAHDRKLTKEAEKVQKNLAEALLEAEKNAKIVEDYHDLYTMQRGRMESDIKLLMTERDIWSSATYEL----------------------------------ALKDTGDLGMVEKLTEKWKKLVNKFKQDVERTEESTKE--KSEIVKAGIIKWQEFFNNNLGKD--VIIPSKRSPFAVALNDFKEYEKMLEEEKEKFTGDFLLSRYDALKVIKRLQENWTDIGFGILSRHKS-MDGLLPPEHEYMEDIVKIISKLYREYEIRINGDNGISKVLPNLVISLDMCVFKLENF---LDYSQVPTEEWL 438 HSP 2 Score: 62.003 bits (149), Expect = 3.266e-9 Identity = 27/59 (45.76%), Postives = 44/59 (74.58%), Query Frame = 1 Query: 640 VLDKSGLNEPFEFNMPTVLHNLLMTVKKEQDLYNVVFHEVIKETTIDCIERGELLANIR 816 +L+++G+ E + PT +H LL +K+EQ +YN VFHE+I++ ++DC +RGELL+ IR Sbjct: 36 MLERAGI-ENENYVGPTKMHQLLNVLKREQSIYNTVFHELIRQVSVDCADRGELLSKIR 93
BLAST of Sterol O-acyltransferase 1 vs. UniProt/SwissProt
Match: sp|Q95LP5|AXDN1_MACFA (Axonemal dynein light chain domain-containing protein 1 OS=Macaca fascicularis OX=9541 GN=AXDND1 PE=2 SV=2) HSP 1 Score: 143.28 bits (360), Expect = 2.916e-61 Identity = 132/522 (25.29%), Postives = 248/522 (47.51%), Query Frame = 3 Query: 876 VVARKILDRRLTEELLRFQNTVSMLSKELSGVKDHEENINQICKQAKLQLKEAVEETKTNADLLREYHDLYEQQRQRLERNVLQLERERDCWRNAAYKITQLVLEHYEIKPAIVLVECESNMISLSQYFVELISVTDNQTLSTIKTKTTQWCNEAQKFALMLAIREENLKTLLNKEIEKINRLKEDF-EDDYLSEQGQLIQPINQEETRKILNSVINWEKSMSEICESFGGQSMLMEEEKLKHMKQLCYEYTDIAVEVFNRHRNETDGSLYQEHSALLDINKLIDEMMTQFMDQLTGDNGVADGIIALQTFEENWITRLSNSVAELYFRPLPDSEWIRFKLLLDDWIALLCESKNAIGTTKLNSITVEGASINKRLEIHEIIQSVDNWSQKSSSGIESENLKLREAIINLKKSMIRWTSQVILRLAPDFPDNSPEAR---RAARLASLGIRELQETAKVLHENISAVSNHIFNCSKDIVTKLMQIKIDTQTEFPDGDSLKLHQLIEFSKSWIEKSEQLLKEI 2429 +V ++++D+R+ EEL F++ + L++EL V+ H+ + + ++A L +A+ + + NA ++ EYHDLY QR+R+E ++ QL ERD W +A Y++ V+E + A L E +++ + L++ D + L+ ++ T +W N KF + EE+ + L + + + +E F E D LS P N ++ W+K ++E E F G +L + + LK +K L +TDI + +FNRH++ +G L E + +I K I ++ ++ ++ GDNG + + L + + +L N L F P EW +++ L N G I ++ S+ L+ + I + W K + I + N++L+ + L SMI+W +++ + P+F D + +A +G+ L+ A L + S ++ + + +VT + K T D ++ +L + WI LL I Sbjct: 308 LVTQRVMDQRILEELYNFKHVIEELTRELCLVRAHDVKLTKETEKAHKDLAQALLDAEKNAKMVEEYHDLYTLQRERMENDMKQLMAERDIWSSATYELALKVIERNRVILARRLYLNEKGWNKYTKHLIILLANKDTEDLALLQKLTQKWRNLVNKFKQEVEEMEESTRETLKIVEKGLTKWQESFNEKDILS-------PNNGNVFDSVILDFKQWQKMLNEKKEEFTGDVLLSKYDTLKIIKHLQENWTDIGLGIFNRHKS-LEGELPSERQYMEEIIKNIQKLYKEYEIRINGDNGYSKILPILISSLDFCSFKLEN----LEFPDTPLEEWQEIDEKINEMKLQLDLLLNLTGIVP-QHIDMDSVSV---LQAY-IFNMIQQWLLKIGNEINNGNIELQRHMDELHISMIQWMVNLLILMIPNFTDQDCLLKLEEESAEKHDIGVARLELDAIELTRKLYQYSRYLSSSCEGMVTAMALSKSTTSHRNATEDLYEVDKLKKECYEWINTCSCLLSNI 812 HSP 2 Score: 117.087 bits (292), Expect = 2.916e-61 Identity = 84/274 (30.66%), Postives = 139/274 (50.73%), Query Frame = 1 Query: 103 LPLLKFKENYSTHSKPA-VKPIPAFLSDEILTNLQQCTNALVCPH-----------EGK----VSNVWSSVIRREKFKHISDNPICICGAGNDLTFLYD--KLPNEIIEHFSDPLINXXXXXXXXXXIEDKMLMRLPEKLDPAEFTLSTHQGMREIQLYDESFTTKPFPHKYHKXXXXXXXXXXXXXXXKIYQSFGDVLDKSGLNEPFEFNMPTVLHNLLMTVKKEQDLYNVVFHEVIKETTIDCIERGELLANIRQRYRNLFFKIPEKIKEFH 870 LP LK K+N SKP + F+ E+L +L NA CP +G V +VW +RR KFK++ D+P+ + GAG D++FLYD + E P + + I L + L P EF + + G+ ++ YD+ +TT + + P M PN ++ +L+++G+ E E+ PT +H LL +KKEQ +YN +FHE+I++ ++DC +RGELL+ +R+RY + +I ++ +F+ Sbjct: 33 LPELKEKKNMVDRSKPLPTSLLNEFIPKEVLLSLTYAANAGPCPENLLPPKKIKTPKGTLPRLVDHVWHHPVRRNKFKYLIDHPVSLTGAGRDISFLYDVKYTKGQTREKAVCPPHLARSLQSHDGVIVPHKPKTLTDTLIPEEFHIVSSTGVSGLECYDDKYTTLLTDSENRLLLFPSMKPNKRVEVAQLNDVMDTMLERAGV-ENQEYTGPTKMHKLLHILKKEQTIYNTIFHELIRQVSVDCADRGELLSKVRERYVQMLDQIARQMIDFY 305
BLAST of Sterol O-acyltransferase 1 vs. UniProt/SwissProt
Match: sp|Q5T1B0|AXDN1_HUMAN (Axonemal dynein light chain domain-containing protein 1 OS=Homo sapiens OX=9606 GN=AXDND1 PE=2 SV=1) HSP 1 Score: 144.821 bits (364), Expect = 1.467e-60 Identity = 134/526 (25.48%), Postives = 250/526 (47.53%), Query Frame = 3 Query: 876 VVARKILDRRLTEELLRFQNTVSMLSKELSGVKDHEENINQICKQAKLQLKEAVEETKTNADLLREYHDLYEQQRQRLERNVLQLERERDCWRNAAYKITQLVLEHYEIKPAIVLVECESNMISLSQYFVELISVTDNQTLSTIKTKTTQWCNEAQKFALMLAIREENLKTLLNKEIEKINRLKEDF-EDDYLSEQGQLIQPINQEETRKILNSVI----NWEKSMSEICESFGGQSMLMEEEKLKHMKQLCYEYTDIAVEVFNRHRNETDGSLYQEHSALLDINKLIDEMMTQFMDQLTGDNGVADGIIALQTFEENWITRLSNSVAELYFRPLPDSEWIRFKLLLDDWIALLCESKNAIGTTKLNSITVEGASINKRLEIHEIIQSVDNWSQKSSSGIESENLKLREAIINLKKSMIRWTSQVILRLAPDFPDNSPEAR---RAARLASLGIRELQETAKVLHENISAVSNHIFNCSKDIVTKLMQIKIDTQTEFPDGDSLKLHQLIEFSKSWIEKSEQLLKEI 2429 +V ++++D+R+ EEL F++ + L++EL V+ H+ + + ++A L +A+ + NA ++ EYHDLY QR+R+E ++ +L ERD W +A Y++ V+E + A L E +++F+ L+S D + L+ ++ T +W N K + EE+ L + + + +E F E D LS I NSV+ W+K ++E E F G +L + + LK +K L + DI + +FNRH++ +G + E + +I K I ++ ++ ++ GDNG + + +L + + +L N L F P EW +++ + L N G I V+ S+ L+ + I + W K + I + N++L+ + L SMI+W +++ + P+F D + +A +G+ L+ A L + S+++ +C K +VT + K + D ++ +L + WI LL I Sbjct: 309 LVTQRVMDQRILEELYNFKHVIEELTRELCLVRAHDVKLTKETEKAHKDLAQALLNAEKNAKIVEEYHDLYTLQRERMENDMKKLVAERDIWSSATYELALKVIERNRVILARRLYLNEKGWNKYTKHFIILLSNKDTEDLALLQKLTQKWRNLVNKLKQEVEQMEESTSETLKIVKDGLIKWQEFFNEKDILSPNKG-----------NIFNSVLLDFKQWQKILNEKKEEFTGDVLLSKYDTLKIIKHLQENWADIGLGIFNRHKS-LEGEMPSERQYMEEIIKNIQKLYKEYEIRINGDNGYSKILPSLISSLDFCSFKLEN----LEFPDTPLEEWQEIDEKINEMKSHLDILLNLTGIVP-QHIDVDSVSV---LQAY-IFNMIQQWLLKIGNEINNGNIELQHHMDELHISMIQWMVNLLILMIPNFTDQDCLLKLEEESAEKHDIGVARLELDAIELTRKLYQYSSYLSSCCKGMVTAMALSKSTNSHKNATEDLYEVDKLKKECYEWINTCSCLLSNI 813 HSP 2 Score: 112.849 bits (281), Expect = 1.467e-60 Identity = 83/274 (30.29%), Postives = 139/274 (50.73%), Query Frame = 1 Query: 103 LPLLKFKENYSTHSKPAVKPIP-AFLSDEILTNLQQCTNALVCPH-----------EGK----VSNVWSSVIRREKFKHISDNPICICGAGNDLTFLYD--KLPNEIIEHFSDPLINXXXXXXXXXXIEDKMLMRLPEKLDPAEFTLSTHQGMREIQLYDESFTTKPFPHKYHKXXXXXXXXXXXXXXXKIYQSFGDVLDKSGLNEPFEFNMPTVLHNLLMTVKKEQDLYNVVFHEVIKETTIDCIERGELLANIRQRYRNLFFKIPEKIKEFH 870 LP LK K+N SK + F+ E+L +L NA CP +G V +VW +RR KFK++ D+P+ + GAG D++FLYD + E P + + I L + L P EF + + G+ ++ YD+ +TT + + P M PN ++ +L+++G+ E E+ PT +H LL +KKEQ +YN++FHE+I++ ++DC +RGELL+ +R+RY + +I ++ +F+ Sbjct: 34 LPELKEKKNMVDRSKLLPTSLQNEFIPKEVLLSLTYAANAGPCPENLLPPKKIKTPKGTLPRLVDHVWHHPVRRNKFKYLIDHPVSLTGAGRDISFLYDVTYAKGQTREKAVCPPHLARSLQSHDGVIVPHKPKTLTDTLIPEEFHIVSSTGVSGLECYDDKYTTLLTDSENRLLLFPSMKPNKRVEVAQLNDVMDTMLERAGV-ENQEYTGPTKMHKLLHILKKEQTIYNMIFHELIRQVSVDCADRGELLSKVRERYVQMLDQIARQMIDFY 306
BLAST of Sterol O-acyltransferase 1 vs. UniProt/SwissProt
Match: sp|Q3UZ57|AXDN1_MOUSE (Axonemal dynein light chain domain-containing protein 1 OS=Mus musculus OX=10090 GN=Axdnd1 PE=1 SV=1) HSP 1 Score: 104.76 bits (260), Expect = 4.307e-36 Identity = 89/337 (26.41%), Postives = 162/337 (48.07%), Query Frame = 3 Query: 876 VVARKILDRRLTEELLRFQNTVSMLSKELSGVKDHEENINQICKQAKLQLKEAVEETKTNADLLREYHDLYEQQRQRLERNVLQLERERDCWRNAAYKITQLVLEHYEIKPAIVLVECESNMISLSQYFVELISVTDNQTLSTIKTKTTQWCNEAQKFALMLAIREENLKTLLNKEIEKINRLK-EDFEDDYLSEQGQLIQPINQEETRKILNSVINWEKSMSEICESFGGQSMLMEEEKLKHMKQLCYEYTDIAVEVFNRHRNETDGSLYQEHSALLDINKLIDEMMTQFMDQLTGDNGVADGIIALQTFEENWITRLSNSVAELYFRPLPDSEWI 1883 +V ++++D+R+ +EL F+N + L++EL V+ H+ + + ++ + L EA+ E + NA ++ +YHDLY QR R+E ++ L ERD W +A Y++ ++ D L ++ T +W KF + EE+ K EI K +K ++F ++ L + +I P + LN +EK + E E F G +L + LK +K+L +TDI + +RH++ DG L EH + DI K+I ++ ++ ++ GDNG++ + L + + +L N L + +P EW+ Sbjct: 97 LVTQRMMDQRILQELYNFKNVIEELTRELCLVQAHDRKLTKEAEKVQKNLAEALLEAEKNAKIVEDYHDLYTMQRGRMESDIKLLMTERDIWSSATYEL----------------------------------ALKDTGDLGMVEKLTEKWKKLVNKFKQDVERTEESTKE--KSEIVKAGIIKWQEFFNNNLGKD--VIIPSKRSPFAVALNDFKEYEKMLEEEKEKFTGDFLLSRYDALKVIKRLQENWTDIGFGILSRHKS-MDGLLPPEHEYMEDIVKIISKLYREYEIRINGDNGISKVLPNLVISLDMCVFKLENF---LDYSQVPTEEWL 391 HSP 2 Score: 70.8626 bits (172), Expect = 4.307e-36 Identity = 31/77 (40.26%), Postives = 55/77 (71.43%), Query Frame = 1 Query: 640 VLDKSGLNEPFEFNMPTVLHNLLMTVKKEQDLYNVVFHEVIKETTIDCIERGELLANIRQRYRNLFFKIPEKIKEFH 870 +L+++G+ E + PT +H LL +K+EQ +YN VFHE+I++ ++DC +RGELL+ IR++Y + I +++ EF+ Sbjct: 19 MLERAGI-ENENYVGPTKMHQLLNVLKREQSIYNTVFHELIRQVSVDCADRGELLSKIREKYVQMLDHIAQQMIEFY 94
BLAST of Sterol O-acyltransferase 1 vs. TrEMBL
Match: A0A3S1BDY7 (Uncharacterized protein OS=Elysia chlorotica OX=188477 GN=EGW08_006097 PE=4 SV=1) HSP 1 Score: 296.59 bits (758), Expect = 5.396e-113 Identity = 169/519 (32.56%), Postives = 299/519 (57.61%), Query Frame = 3 Query: 876 VVARKILDRRLTEELLRFQNTVSMLSKELSGVKDHEENINQICKQAKLQLKEAVEETKTNADLLREYHDLYEQQRQRLERNVLQLERERDCWRNAAYKITQLVLEHYEIKPAIVLVECESNMISLSQYFVELISVTDNQTLSTIKTKTTQWCNEAQKFALMLAIREENLKTLLNKEIEKINRLKEDFEDDYL-SEQGQLIQPINQEETRKILNSVINWEKSMSEICESFGGQSMLMEEEKLKHMKQLCYEYTDIAVEVFNRHRNETDGSLYQEHSALLDINKLIDEMMTQFMDQLTGDNGVADGIIALQTFEENWITRLSNSVAELYFRPLPDSEWIRFKLLLDDWIALLCESKNAIGTTKLNSITVEGASINKRLEIHEIIQSVDNWSQKSSSGIESENLKLREAIINLKKSMIRWTSQVILRLAPDFPDNSPEARRAARLASLGIRELQETAKVLHENISAVSNHIFNCSKDIVTKLMQIKIDTQTEFPDGDSLKLHQLIEFSKSWIEKSEQLLKEI 2429 V+A++ LDRRLT+EL+RF+ T+ +L+ EL+ VK+H+ + + ++A+ L+ A+ E++ NA LL EYHDLYE QR+RLER V L ER+ W AAY + V E Y++ A L E + ++ +F L+S D L+ I++ W + + F + L RE+ +K L I + F+ ++ +E G + +P + + R +L+ + +W++++ + +GG ++L +E+L +++ +TD A++VF RHR D +Q+ + +N+ +D+++TQF +++G+NGVA II LQ+ E W T++++ PLPD+EW L++W+ L+ ++ +GT++ + +G + ++IH++++ W+ +S+ I+SE+ KL E + +L M+RW QV+LRLAPD NS EA A L ++ I +L E K L E+I A SN++ C IV + Q + D E D + L +L + WI ++ L+ ++ Sbjct: 305 VMAQRALDRRLTDELMRFKGTIGVLTSELTDVKEHDRKVTKEAQKAQEDLRSALIESQKNASLLAEYHDLYELQRRRLERQVFMLSEEREVWSTAAYSLALKVTEEYQLNTAKRLQLSEKGWVKMANHFTILLSDRDTDLLTKIQSYVENWRDLIEDFNIALRQREDEMKESLKGVRTSIESTLKTFQTRFVDTENGSVRRP-DDDFVRTLLSGIKSWDEAIVRETDVYGGDNLLNSQEELAQIRREMDGWTDAALKVFGRHRG-PDNKTHQDQHNMNALNEEVDQLLTQFHHRISGENGVAGLIINLQSSLETWETKVTSHAQGTL--PLPDTEWGAIYQTLEEWLVLVQQAYEYVGTSQRDEDRQDGRP-HVSIDIHDVVRKTQKWATTASNSIDSEDAKLVEQVSSLHSEMVRWMVQVLLRLAPDKEGNSKEAAEMALLGTVSIPQLIEVVKTLFESIEAFSNYVTLCCNGIVMENTQARQDNNEENADHELKDLAKLRSECEDWIHTAQILMSQL 818 HSP 2 Score: 144.05 bits (362), Expect = 5.396e-113 Identity = 79/220 (35.91%), Postives = 139/220 (63.18%), Query Frame = 1 Query: 247 SNVWSSVIRREKFKHISDNPICICGAGNDLTFLYDKLPNEIIEHFSDPLINXXXXXXXXXXIEDKMLMRLPEKLDPAEFTLSTHQGMREIQLYDESFTTKPFPHKYHKXXXXXXXXXXXXXXXKIYQSFGDVLDKSGLNEPFEFNM-----PTVLHNLLMTVKKEQDLYNVVFHEVIKETTIDCIERGELLANIRQRYRNLFFKIPEKIKEFHDK*LHEK 891 +NVW+ RR++FKH+ +N C CGAG D++FLYD +P + +++ +K + +K L +LP L P E+ + ++G+ I + + ++TKP H+ H + P M P + ++ Q+ ++LDK+G+N+ +M PT +HNLL +KKEQ++YNVVFHE+I++T+++C+ERGELLA +R +Y +L K+P++I H++ + ++ Sbjct: 96 ANVWNHK-RRDRFKHLLENTPCACGAGKDISFLYD-VPQSTVHPPKPDILDKSAVRKSDGALPNKPL-QLPNTLLPDEYHIVKNKGVVGIDYHADRYSTKPEDHEKHLVVFPSMKPGSRYEVLQLKQALANMLDKAGVND---LDMEGGSGPTQMHNLLDLIKKEQNIYNVVFHELIRQTSVECVERGELLAELRSKYSDLLNKVPQQIMSLHEEVMAQR 309
BLAST of Sterol O-acyltransferase 1 vs. TrEMBL
Match: A0A267FB17 (Uncharacterized protein OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig017795g2 PE=4 SV=1) HSP 1 Score: 296.975 bits (759), Expect = 4.648e-112 Identity = 176/521 (33.78%), Postives = 294/521 (56.43%), Query Frame = 3 Query: 876 VVARKILDRRLTEELLRFQNTVSMLSKELSGVKDHEENINQICKQAKLQLKEAVEETKTNADLLREYHDLYEQQRQRLERNVLQLERERDCWRNAAYKITQLVLEHYEIKPAIVLVECESNMISLSQYFVELISVTDNQTLSTIKTKTTQWCNEAQKFALMLAIREENLKTLLNKEIEKINRLKEDFEDDYLSEQGQLIQPINQEETRKILNSVINWEKSMSEICESFGGQSMLMEEEKLKHMKQLCYEYTDIAVEVFNRHRNETDGSLYQEHSALLDINKLIDEMMTQFMDQLTGDNGVADGIIALQTFEENWITRLSNSVAELYFRPLPDSEWIRFKLLLDDWIALLCESKNAIGTTKLNSITVEGASINKR---LEIHEIIQSVDNWSQKSSSGIESENLKLREAIINLKKSMIRWTSQVILRLAPDFPDNSPEARRAARLASLGIRELQETAKVLHENISAVSNHIFNCSKDIVTKLMQIKIDTQTEFPDGDSLKLHQLIEFSKSWIEKSEQLLKEI 2429 V+A++ LDRRLTEELLRF+ T+ +L+ EL+ VKDH+ I+ + + +L++A+EE K +ADLL EYH LYE QR RLE V QL ER+ W + AY + V+E ++ L E L+ +F L+S D + L+ ++ W + F L +R+++ + L K E + L+E+FED +L +L Q + E T ++L + E +++ +FGG ML +E + M++L + D V +F RHR E DG+ + E + ++ L++++M Q +L G+NGVA G+I LQ E W TRL + + LP+ EW RF L++DW+ L+ E+ +A+G+T E N+R L+ + ++ V W+ K +SGI+SE+ ++ E+ L M+RW Q +LRLAPD+P NS EA +AA +AS EL + K L E ++ + ++ + IV+ ++ ++ + E D + +L +L ++ W + +L+++ Sbjct: 317 VMAQRALDRRLTEELLRFKTTIGVLTAELADVKDHDRQISGEARATQEELRKALEEAKRSADLLGEYHGLYELQRARLEDQVSQLTEERELWSHTAYCLALKVMEETQLVSCKRLHAAEKAWQHLAGHFSVLLSERDTEDLARVQALVDTWREKVDVFVGHLRVRDDSSRKNLTKLRELVTGLQENFEDQFLDGPARLKQLLTAENTSQVLGKLRELEALLNKEANAFGGDVMLDLQESMASMRRLMLTWNDTCVTLFARHRAE-DGAEFPEKKTMSAVSSLVEKLMRQLNIRLIGENGVARGVINLQNILETWTTRLQSVLNTGKL--LPEQEWTRFYALIEDWLGLIDETISAVGST-----AKEDQPANQREPSLDPNMVVTEVGKWANKVASGIDSEDTRMTESAKQLHIGMLRWMIQSLLRLAPDYPGNSQEAHQAALMASATPEELLASFKELGEWLTKFTVYLADSCSVIVSGIVAQRMAVKDEDFDNEQAELIRLKTEARDWCHAATCILEDL 829 HSP 2 Score: 140.584 bits (353), Expect = 4.648e-112 Identity = 78/232 (33.62%), Postives = 133/232 (57.33%), Query Frame = 1 Query: 241 KVSNVWSSVIRREKFKHISDNPICICGAGNDLTFLYDKLPNEI--------IEHFSDPLI-------NXXXXXXXXXXIEDKMLMRLPEKLDPAEFTLSTHQGMREIQLYDESFTTKPFPHKYHKXXXXXXXXXXXXXXXKIYQSFGDVLDKSGLNEPFEFNMPTVLHNLLMTVKKEQDLYNVVFHEVIKETTIDCIERGELLANIRQRYRNLFFKIPEKIKEFHDK*LHEK 891 K SNVW+ RREK KH++D+ IC+CGAG D++FLYD P+ + DP + ++ ++ + + RLP+ L P EF + ++ + ++ +T+ H+ H + P + P + ++ ++F +L G++E FE PT +H LL VK+EQD+YNVVFHE+I++ T++C+ERG+LL+ +R RY L K+P ++K HD+ + ++ Sbjct: 91 KPSNVWNYPKRREKLKHLTDSTICVCGAGKDISFLYDA-PSAVKSLEAKATATATEDPSLVREQARKQKQQRRRLQAQGGEPKEARLPDTLIPEEFHVVKNKAVVGLEYNPSDHSTQLEDHEKHLVMFPSLKPTSRWEVLQLSKTFDQMLASVGVDEEFEVTGPTQMHRLLDLVKREQDVYNVVFHELIRQVTVECVERGQLLSTLRGRYNLLLSKVPAQVKSLHDEVMAQR 321
BLAST of Sterol O-acyltransferase 1 vs. TrEMBL
Match: A0A267FME5 (Uncharacterized protein (Fragment) OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig006576g2 PE=4 SV=1) HSP 1 Score: 295.049 bits (754), Expect = 1.832e-111 Identity = 176/521 (33.78%), Postives = 293/521 (56.24%), Query Frame = 3 Query: 876 VVARKILDRRLTEELLRFQNTVSMLSKELSGVKDHEENINQICKQAKLQLKEAVEETKTNADLLREYHDLYEQQRQRLERNVLQLERERDCWRNAAYKITQLVLEHYEIKPAIVLVECESNMISLSQYFVELISVTDNQTLSTIKTKTTQWCNEAQKFALMLAIREENLKTLLNKEIEKINRLKEDFEDDYLSEQGQLIQPINQEETRKILNSVINWEKSMSEICESFGGQSMLMEEEKLKHMKQLCYEYTDIAVEVFNRHRNETDGSLYQEHSALLDINKLIDEMMTQFMDQLTGDNGVADGIIALQTFEENWITRLSNSVAELYFRPLPDSEWIRFKLLLDDWIALLCESKNAIGTTKLNSITVEGASINKR---LEIHEIIQSVDNWSQKSSSGIESENLKLREAIINLKKSMIRWTSQVILRLAPDFPDNSPEARRAARLASLGIRELQETAKVLHENISAVSNHIFNCSKDIVTKLMQIKIDTQTEFPDGDSLKLHQLIEFSKSWIEKSEQLLKEI 2429 V+A++ LDRRLTEELLRF+ T+ +L+ EL VKDH+ I+ + + +L++A+EE K +ADLL EYH LYE QR RLE V QL ER+ W + AY + V+E ++ L E L+ +F L+S D + L+ ++ W + F L +R+++ + L K E + L+E+FED +L +L Q + E T ++L + E +++ +FGG ML +E + M++L + D V +F RHR E DG+ + E + ++ L++++M Q +L G+NGVA G+I LQ E W TRL + + LP+ EW RF L++DW+ L+ E+ +A+G+T E N+R L+ + ++ V W+ K +SGI+SE+ ++ E+ L M+RW Q +LRLAPD+P NS EA +AA +AS EL + K L E ++ + ++ + IV+ ++ ++ + E D + +L +L ++ W + +L+++ Sbjct: 325 VMAQRALDRRLTEELLRFKTTIGVLTAELVDVKDHDRQISGEARATQEELRKALEEAKRSADLLGEYHGLYELQRARLEDQVSQLTEERELWSHTAYCLALKVMEETQLVSCKRLHAAEKAWQHLAGHFSVLLSERDTEDLARVQALVDTWREKVDVFVGHLRVRDDSSRKNLTKLRELVTGLQENFEDQFLDGPARLKQLLTAENTSQVLGKLRELEALLNKEANAFGGDVMLDLQESMASMRRLMLTWNDTCVTLFARHRAE-DGAEFPEKKTMSAVSSLVEKLMRQLNIRLIGENGVARGVINLQNILETWTTRLQSVLNTGKL--LPEQEWTRFYALIEDWLGLIDETISAVGST-----AKEDQPANQREPSLDPNMVVTEVGKWANKVASGIDSEDTRMTESAKQLHIGMLRWMIQSLLRLAPDYPGNSQEAHQAALMASATPEELLASFKELGEWLTKFTVYLADSCSVIVSGIVAQRMAVKDEDFDNEQAELIRLKTEARDWCHAATCILEDL 837 HSP 2 Score: 140.584 bits (353), Expect = 1.832e-111 Identity = 78/232 (33.62%), Postives = 133/232 (57.33%), Query Frame = 1 Query: 241 KVSNVWSSVIRREKFKHISDNPICICGAGNDLTFLYDKLPNEI--------IEHFSDPLI-------NXXXXXXXXXXIEDKMLMRLPEKLDPAEFTLSTHQGMREIQLYDESFTTKPFPHKYHKXXXXXXXXXXXXXXXKIYQSFGDVLDKSGLNEPFEFNMPTVLHNLLMTVKKEQDLYNVVFHEVIKETTIDCIERGELLANIRQRYRNLFFKIPEKIKEFHDK*LHEK 891 K SNVW+ RREK KH++D+ IC+CGAG D++FLYD P+ + DP + ++ ++ + + RLP+ L P EF + ++ + ++ +T+ H+ H + P + P + ++ ++F +L G++E FE PT +H LL VK+EQD+YNVVFHE+I++ T++C+ERG+LL+ +R RY L K+P ++K HD+ + ++ Sbjct: 99 KPSNVWNYPKRREKLKHLTDSTICVCGAGKDISFLYDA-PSAVKSLEAKATATATEDPSLVREQARKQKQQRRRLQAQGGEPKEARLPDTLIPEEFHVVKNKAVVGLEYNPSDHSTQLEDHEKHLVMFPSLKPTSRWEVLQLSKTFDQMLASVGVDEEFEVTGPTQMHRLLDLVKREQDVYNVVFHELIRQVTVECVERGQLLSTLRGRYNLLLSKVPAQVKSLHDEVMAQR 329
BLAST of Sterol O-acyltransferase 1 vs. TrEMBL
Match: A0A267GIS2 (Uncharacterized protein (Fragment) OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig008529g2 PE=4 SV=1) HSP 1 Score: 293.893 bits (751), Expect = 4.003e-111 Identity = 176/521 (33.78%), Postives = 293/521 (56.24%), Query Frame = 3 Query: 876 VVARKILDRRLTEELLRFQNTVSMLSKELSGVKDHEENINQICKQAKLQLKEAVEETKTNADLLREYHDLYEQQRQRLERNVLQLERERDCWRNAAYKITQLVLEHYEIKPAIVLVECESNMISLSQYFVELISVTDNQTLSTIKTKTTQWCNEAQKFALMLAIREENLKTLLNKEIEKINRLKEDFEDDYLSEQGQLIQPINQEETRKILNSVINWEKSMSEICESFGGQSMLMEEEKLKHMKQLCYEYTDIAVEVFNRHRNETDGSLYQEHSALLDINKLIDEMMTQFMDQLTGDNGVADGIIALQTFEENWITRLSNSVAELYFRPLPDSEWIRFKLLLDDWIALLCESKNAIGTTKLNSITVEGASINKR---LEIHEIIQSVDNWSQKSSSGIESENLKLREAIINLKKSMIRWTSQVILRLAPDFPDNSPEARRAARLASLGIRELQETAKVLHENISAVSNHIFNCSKDIVTKLMQIKIDTQTEFPDGDSLKLHQLIEFSKSWIEKSEQLLKEI 2429 V+A++ LDRRLTEELLRF+ T+ +L+ EL VKDH+ I+ + + +L++A+EE K +ADLL EYH LYE QR RLE V QL ER+ W + AY + V+E ++ L E L+ +F L+S D + L+ ++ W + F L +R+++ + L K E + L+E+FED +L +L Q + E T ++L + E +++ +FGG ML +E + M++L + D V +F RHR E DG+ + E + ++ L++++M Q +L G+NGVA G+I LQ E W TRL + + LP+ EW RF L++DW++L+ E+ A+G+T E N+R L+ + ++ V W+ K +SGI+SE+ ++ E+ L M+RW Q +LRLAPD+P NS EA +AA +AS EL + K L E ++ + ++ + IV+ ++ ++ + E D + +L +L ++ W + +L+++ Sbjct: 323 VMAQRALDRRLTEELLRFKTTIGVLTAELVDVKDHDRQISGEARATQEELRKALEEAKRSADLLGEYHGLYELQRARLEDQVSQLTEERELWSHTAYCLALKVMEETQLVSCKRLHAAEKAWQHLAGHFSVLLSERDTEDLARVQALVDTWREKVDVFVGHLRVRDDSSRKNLTKLRELVTGLQENFEDQFLDGPARLKQLLTVENTSQVLGKLRELEALLNKEANAFGGDVMLDLQESMASMRRLMLTWNDTCVTLFARHRAE-DGAEFPEKKTMSAVSSLVEKLMRQLNIRLIGENGVARGVINLQNILETWTTRLQSVLNTGKL--LPEQEWTRFYALIEDWLSLIDETIAAVGST-----AKEDQPANQREPSLDPNMVVTEVGKWANKVASGIDSEDTRMTESAKQLHIGMLRWMIQSLLRLAPDYPGNSQEAHQAALMASATPEELLASFKELGEWLTKFTVYLADSCSVIVSGIVAQRMAVKDEDFDNEQAELIRLKTEARDWCHAATCILEDL 835 HSP 2 Score: 140.584 bits (353), Expect = 4.003e-111 Identity = 78/232 (33.62%), Postives = 133/232 (57.33%), Query Frame = 1 Query: 241 KVSNVWSSVIRREKFKHISDNPICICGAGNDLTFLYDKLPNEI--------IEHFSDPLI-------NXXXXXXXXXXIEDKMLMRLPEKLDPAEFTLSTHQGMREIQLYDESFTTKPFPHKYHKXXXXXXXXXXXXXXXKIYQSFGDVLDKSGLNEPFEFNMPTVLHNLLMTVKKEQDLYNVVFHEVIKETTIDCIERGELLANIRQRYRNLFFKIPEKIKEFHDK*LHEK 891 K SNVW+ RREK KH++D+ IC+CGAG D++FLYD P+ + DP + ++ ++ + + RLP+ L P EF + ++ + ++ +T+ H+ H + P + P + ++ ++F +L G++E FE PT +H LL VK+EQD+YNVVFHE+I++ T++C+ERG+LL+ +R RY L K+P ++K HD+ + ++ Sbjct: 97 KPSNVWNYPKRREKLKHLTDSTICVCGAGKDISFLYDA-PSAVKSLEAKATATATEDPSLVREQARKQKQQRRRLQAQGGEPKEARLPDTLIPEEFHVVKNKAVVGLEYNPSDHSTQLEDHEKHLVMFPSLKPTSRWEVLQLSKTFDQMLASVGVDEEFEVTGPTQMHRLLDLVKREQDVYNVVFHELIRQVTVECVERGQLLSTLRGRYNLLLSKVPAQVKSLHDEVMAQR 327
BLAST of Sterol O-acyltransferase 1 vs. TrEMBL
Match: A0A1I8GAA9 (Uncharacterized protein OS=Macrostomum lignano OX=282301 PE=4 SV=1) HSP 1 Score: 290.426 bits (742), Expect = 4.853e-110 Identity = 174/503 (34.59%), Postives = 285/503 (56.66%), Query Frame = 3 Query: 876 VVARKILDRRLTEELLRFQNTVSMLSKELSGVKDHEENINQICKQAKLQLKEAVEETKTNADLLREYHDLYEQQRQRLERNVLQLERERDCWRNAAYKITQLVLEHYEIKPAIVLVECESNMISLSQYFVELISVTDNQTLSTIKTKTTQWCNEAQKFALMLAIREENLKTLLNKEIEKINRLKEDFEDDYLSEQGQLIQPINQEETRKILNSVINWEKSMSEICESFGGQSMLMEEEKLKHMKQLCYEYTDIAVEVFNRHRNETDGSLYQEHSALLDINKLIDEMMTQFMDQLTGDNGVADGIIALQTFEENWITRLSNSVAELYFRPLPDSEWIRFKLLLDDWIALLCESKNAIGTTKLNSITVEGASINKR---LEIHEIIQSVDNWSQKSSSGIESENLKLREAIINLKKSMIRWTSQVILRLAPDFPDNSPEARRAARLASLGIRELQETAKVLHENISAVSNHIFNCSKDIVTKLMQIKIDTQTEFPDGDSLKLHQL 2375 V+A++ LDRRLTEELLRF+ T+ +L+ EL VKDH+ I+ + + +L++A+EE K +ADLL EYH LYE QR RLE V QL ER+ W + AY + V+E ++ L E L+ +F L+S D + L+ ++ W + F L +R+++ + L K E + L+E+FED +L +L Q + E T ++L + E +++ +FGG ML +E + M++L + D V +F RHR E DG+ + E + ++ L++++M Q +L G+NGVA G+I LQ E W TRL + + + LP+ EW RF L++DW+ L+ E+ +A+G+T E N+R L+ + ++ V W+ K +SGI+SE+ ++ E+ L M+RW Q +LRLAPD+P NS EA +AA +AS EL + K L E ++ + ++ + IV+ ++ ++ + E D + +L +L Sbjct: 318 VMAQRALDRRLTEELLRFKTTIGVLTAELVDVKDHDRQISGEARATQEELRKALEEAKRSADLLGEYHGLYELQRARLEDQVSQLTEERELWSHTAYCLALKVMEETQLVSCKRLHAAEKAWQHLAGHFSVLLSERDTEDLARVQALVDTWREKVDVFVGHLRVRDDSSRKNLTKLRELVTGLQENFEDQFLDGPARLKQLLTAENTSQVLGKLRELEALLNKEANAFGGDVMLDLQESMASMRRLMLTWNDTCVTLFARHRAE-DGAEFPEKKTMSAVSSLVEKLMRQLNIRLIGENGVARGVINLQNILETWTTRLQSVLN--TGKLLPEQEWTRFYALIEDWLGLIDETISAVGST-----AKEDQPANQREPSLDPNMVVTEVGKWANKVASGIDSEDTRMTESAKQLHIGMLRWMIQSLLRLAPDYPGNSQEAHQAALMASATPEELLASFKELGEWLTKFTVYLADSCSVIVSGIVAQRMAVKDEDFDNEQAELIRL 812 HSP 2 Score: 140.198 bits (352), Expect = 4.853e-110 Identity = 78/232 (33.62%), Postives = 133/232 (57.33%), Query Frame = 1 Query: 241 KVSNVWSSVIRREKFKHISDNPICICGAGNDLTFLYDKLPNEI--------IEHFSDPLI-------NXXXXXXXXXXIEDKMLMRLPEKLDPAEFTLSTHQGMREIQLYDESFTTKPFPHKYHKXXXXXXXXXXXXXXXKIYQSFGDVLDKSGLNEPFEFNMPTVLHNLLMTVKKEQDLYNVVFHEVIKETTIDCIERGELLANIRQRYRNLFFKIPEKIKEFHDK*LHEK 891 K SNVW+ RREK KH++D+ IC+CGAG D++FLYD P+ + DP + ++ ++ + + RLP+ L P EF + ++ + ++ +T+ H+ H + P + P + ++ ++F +L G++E FE PT +H LL VK+EQD+YNVVFHE+I++ T++C+ERG+LL+ +R RY L K+P ++K HD+ + ++ Sbjct: 92 KPSNVWNYPKRREKLKHLTDSTICVCGAGKDISFLYDA-PSAVKSLEAKATATATEDPSLVREQARKQKQQRRRLQAQGGEPKEARLPDTLIPEEFHVVKNKAVVGLEYNPSDHSTQLEDHEKHLVMFPSLKPTSRWEVLQLSKTFDQMLASVGVDEEFEVTGPTQMHRLLDLVKREQDVYNVVFHELIRQVTVECVERGQLLSTLRGRYNLLLSKVPAQVKSLHDEVMAQR 322
BLAST of Sterol O-acyltransferase 1 vs. Ensembl Cavefish
Match: axdnd1 (axonemal dynein light chain domain containing 1 [Source:NCBI gene;Acc:103025755]) HSP 1 Score: 162.155 bits (409), Expect = 1.410e-67 Identity = 129/546 (23.63%), Postives = 268/546 (49.08%), Query Frame = 3 Query: 879 VARKILDRRLTEELLRFQNTVSMLSKELSGVKDHEENINQICKQAKLQLKEAVEETKTNADLLREYHDLYEQQRQRLERNVLQLERERDCWRNAAYKITQLVLEHYEIKPAIVLVECESNMISLSQYFVELISVTDNQTLSTIKTKTTQWCNEAQKFALMLAIREEN----LKTLLNKEIEKINRLKED--FEDDYLSE---QGQLIQPINQEETRKILNSVINWEKSMSEICESFGGQSMLMEEEKLKHMKQLCYEYTDIAVEVFNRHRNETDGSLYQEHSALLDINKLIDEMMTQFMDQLTGDNGVADGIIALQTFEENWITRLSNSVAELYFRPLPDSEWIRFKLLLDDWIALLCESKNAIGTTKLNSITVEGASINKRLEIHEIIQSVDNWSQKSSSGIESENLKLREAIINLKKSMIRWTSQVILRLAPDFPDNS----PEARRAARLASLGIRELQETAKVLHENISAVSNHIFNCSKDIVTKLMQIKI---DTQTEFPDGDSLKLHQLIEFSKSWIEKSEQLLKEIMELEYETQNKMRS 2468 +A++ LDRRL EE++ F+++++ L++ELS +++H+++++ ++A+ +L +A+E+++ +D++ EYH LYE QR+RLE V L ERD W Y I V++ ++ L E + +F ++ D++ L+ I T QW F L E N ++T + I K ++ ED D +E +G+L + + Q W ++ +CE +GG+ +L +E L + +L + ++ +++ RH D Q + + +++ + E+ Q ++ G++G+ +I+L E W +L + + LP ++W+ ++ L W+ L ++ + +T+ S ++ + + ++E+ E+ ++ ++ ++ + ENL L E + ++ + RW ++L++ PD D+ P + + +++L+E AK L + + S +I + IV + +Q I D + E L ++ W+E + LL +I E Q RS Sbjct: 320 LAQRALDRRLMEEIICFKHSITQLNEELSKLREHDDHVSSQAEKAQEELAKALEQSRHKSDMVEEYHKLYEMQRKRLEGQVATLTEERDLWSKITYSIALKVVKLKNLQLVSRLHVSEQTWSRTADHFTRFLTTKDSEDLNHIMQLTDQWREHLTSFMKKLKEIERNQCEVIRT-IQSGIAKWHKFCEDNIRNPDMKNEKEPEGELCEDLKQ------------WSTELTRVCERYGGEDLLSFQEILNTLTELQAAWVEVFLKLVRRHLG-PDREPPQGQATMRELSGAVTELHKQLGTRVNGESGIHKQLISLGGAMELWTNKLQSLIGRNEV--LPATDWLELEMALGSWVRLSEKALLNVDSTQPESEKIK-QTPHTKIEVDEVFSTLRDFLSSQNNFFDYENLTLCEEVSSMHVLLTRWMVDLLLQMVPDRRDDQEPPLPTDTELSIFKDVSLQKLEEDAKNLSQKLYYFSKYITGSCQAIVEEEIQKNITHDDKENEL-----FHLSKIQRECAEWVEVCQILLSDITGHPVELQRTDRS 843 HSP 2 Score: 115.931 bits (289), Expect = 1.410e-67 Identity = 68/223 (30.49%), Postives = 119/223 (53.36%), Query Frame = 1 Query: 253 VWSSVIRREKFKHISDNPICICGAGNDLTFLYDKLPNEIIEHFSDPLINXXXXXXXXXXIEDKMLMRLPEKLDPAEFTLSTHQGMREIQLYDESFTT---------KPFPHKYHKXXXXXXXXXXXXXXXKIYQSFGDVLDKSGLNEPFE-FNMPTVLHNLLMTVKKEQDLYNVVFHEVIKETTIDCIERGELLANIRQRYRNLFFKIPEKIKEFHDK*LHEK 891 VW + R+K++++ D P + GAG D++FL D L + P+ + + + + L P E+ L H+G+R +Q YDE FT K FP M P+ + ++ + D+L+K+G+++ FE + +H LL V+ EQ+++N+VFHE+I++ +++C ERG+LLA +RQRY L +IP ++K H + L ++ Sbjct: 114 VWHYSVARKKYQYLLDQPTSVTGAGRDISFLCDALAGQKQRIHLPPMTDRGSIQSHDVLKDSNSIG----TLIPEEYHLVKHKGLRGLQCYDEKFTVLLKDDENKFKIFP---------SMKPSGRLEAVQLMRVMDDMLEKAGVSQEFEELTGLSQMHGLLELVRVEQNIFNIVFHELIRQVSVECAERGQLLAKLRQRYVALLDRIPRQLKGLHTENLAQR 323
BLAST of Sterol O-acyltransferase 1 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000003307.1 (pep scaffold:Pmarinus_7.0:GL477417:7150:25215:1 gene:ENSPMAG00000003022.1 transcript:ENSPMAT00000003307.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 103.99 bits (258), Expect = 2.422e-39 Identity = 68/212 (32.08%), Postives = 112/212 (52.83%), Query Frame = 1 Query: 253 VWSSVIRREKFKHISDNPICICGAGNDLTFLYDKLPNEIIEHFSDPLINXXXXXXXXXXIEDKMLMRLP-----EKLDPAEFTLSTHQGMREIQLYDESFTTKPFPHKYHKXXXXXXXXXXXXXXXKIYQSFGDVLDKSGLNEPFEFNMPTVLHNLLMTVKKEQDLYNVVFHEVIKETTIDCIERGELLANIR-QRYRNLFFKIPEKIKEFH 870 VW +R KF H++D P+C+ GAG +L FL D + ++ D I + + + D M++ P E P EF + + G+ +QL D +TT + + + P M P + ++ + L+K G P E PT +H+LL V++EQ +YN VFHEVI++ ++ C+ERG+LLA +R +RY +L ++P + H Sbjct: 6 VWHYPQQRSKFTHLTDQPVCLTGAGRNLAFLEDS-SYVLFKNLLDAYIMLMVASRLAST--DNMIVAQPKEVLSETFIPEEFHIIQNHGVVGLQLKDSKYTTYLEDDEKNMRTFPSMRPMARNEVVELTRVLDTWLEKLG---PMEIEGPTSIHSLLQLVQQEQCIYNAVFHEVIRQVSVQCMERGQLLAKLRWERYSSLLSRVPVLVAGLH 211 HSP 2 Score: 77.411 bits (189), Expect = 2.422e-39 Identity = 47/158 (29.75%), Postives = 85/158 (53.80%), Query Frame = 3 Query: 876 VVARKILDRRLTEELLRFQNTVSMLSKELSGVKDHEENINQICKQAKLQLKEAVEETKTNADLLREYHDLYEQQRQRLERNVLQLERERDCWRNAAYKITQLVLEHYEIKPAIVLVECESNMISLSQYFVELISVTDNQTLSTIKTKTTQWCNEAQKF 1349 V+A + RRL E+L FQ +V+ ++ ELS V++ + +N ++ + LK + E++ NA+LL EYH +Y R RLE ++ L+RERD W +AA + + E I L +++Q + L+S D ++ +++ + W +A + Sbjct: 214 VLATRAQHRRLMEQLTAFQTSVNRMASELSSVRERDGRVNAQAQREREDLKRVLNESRRNANLLEEYHSVYGLHRHRLESSMGVLQRERDGWASAALALASQLTEERSIVTVRRLRGHSQAWANVAQQHLLLLSNRDGSVVAEVRSLVSSWAEKAARL 371
BLAST of Sterol O-acyltransferase 1 vs. Ensembl Nematostella
Match: EDO47152 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RMT0]) HSP 1 Score: 135.961 bits (341), Expect = 5.280e-65 Identity = 75/209 (35.89%), Postives = 123/209 (58.85%), Query Frame = 1 Query: 247 SNVWSSVIRREKFKHISDNPICICGAGNDLTFLYDKLPNEIIEHFSDPLINXXXXXXXXXXIEDKMLMRLPEKLDPAEFTLSTHQGMREIQLYDESFTTKPFPHKYHKXXXXXXXXXXXXXXXKIYQSFGDVLDKSGLNEPF-EFNMPTVLHNLLMTVKKEQDLYNVVFHEVIKETTIDCIERGELLANIRQRYRNLFFKIPEKIKEFH 870 +NVW+ REK KH+ + P C+CGAG D++FLYD + + + L S +R + D ++P+ L P+E+ + + G+ ++ +DE +TT H+ H P M P+ K+ + +L ++G ++ E PT +HNLL VKKEQ++YNV F+E+I++ T++C ERGELLA++R+RY L +IP ++K H Sbjct: 47 ANVWNYPKGREKLKHLVEQPPCLCGAGKDISFLYDAVQEKQSPEVTKTLEKIPASVEREIQALDGS-SQIPDTLLPSEYHIVKNPGVMGLEFHDEKYTTYVHDHEDHLTVFPSMKPSGRQEVLKLKHAMASLLARAGADDDGKELTGPTQIHNLLELVKKEQNIYNVCFNEIIRQVTVECTERGELLADLRRRYSGLLDRIPRQVKSLH 254 HSP 2 Score: 132.109 bits (331), Expect = 5.280e-65 Identity = 88/284 (30.99%), Postives = 152/284 (53.52%), Query Frame = 3 Query: 876 VVARKILDRRLTEELLRFQNTVSMLSKELSGVKDHEENINQICKQAKLQLKEAVEETKTNADLLREYHDLYEQQRQRLERNVLQLERERDCWRNAAYKITQLVLEHYEIKPAIVLVECESNMISLSQYFVELISVTDNQTLSTIKTKTTQWCNEAQKFALMLAIREENLKTLLNKEIEK----INRLKEDFEDDYLSEQGQLIQPINQEETRKILNSVINWEKSMSEICESFGGQSMLMEEEKLKHMKQLCYEYTDIAVEVFNRHRNETDGSLYQEHSALLDIN 1715 V+A++ LDRRLTEEL+RF+ ++S L+ EL+ VK H+ + Q +A+ L+EA+ E++ NA LL EYH LYE QR RL+ + L ERD W +AAY + V + + + A L CE L+++F +S D+ ++T+ + F + AI NL+ K I+ + + E D + I ++++ + WE+ ++ E F G+ +L E++L HM + ++TD+A++VF RH+ +G + +H + ++N Sbjct: 257 VIAQRALDRRLTEELVRFKASISALTGELASVKAHDREVTQQAIEAQRNLEEALHESEKNASLLSEYHGLYELQRNRLQAQIGSLTEERDLWGSAAYTLALKVTDKHSLNTAKKLHLCEKAWAKLARHFAIFLSEKDSIQVNTLLLPGILLLAQ-DNFMRIPAIISLNLEPNNAKRIKPFMICLVFANDSLETDVTIPSQKFISDLSED--------MKAWEEVFNQEAERFTGEVLLAREDELYHMNKQVDKWTDVALKVFGRHQT-PEGERWPQHIEMKELN 530
BLAST of Sterol O-acyltransferase 1 vs. Ensembl Nematostella
Match: EDO32969 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7STJ9]) HSP 1 Score: 48.521 bits (114), Expect = 2.326e-6 Identity = 27/71 (38.03%), Postives = 36/71 (50.70%), Query Frame = 3 Query: 1059 DLLREYHDLYEQQRQRLERNVLQLERERDCWRNAAYKITQLVLEHYEIKPAIVLVECESNMISLSQYFVEL 1271 LL EYH LYE QR RL+ + L ERD W +AAY + V + + + A L CE ++ F L Sbjct: 23 SLLSEYHGLYELQRNRLQAQIGSLTEERDLWGSAAYTLALKVTDKHSLNTAKKLHLCEKSLGKARAPFRHL 93
BLAST of Sterol O-acyltransferase 1 vs. Ensembl Medaka
Match: ENSORLT00000010925.2 (pep primary_assembly:ASM223467v1:4:14252955:14257409:-1 gene:ENSORLG00000008702.2 transcript:ENSORLT00000010925.2 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 68.1662 bits (165), Expect = 2.501e-17 Identity = 35/100 (35.00%), Postives = 61/100 (61.00%), Query Frame = 1 Query: 616 KIYQSFGDVLDKSGLNEPFE--------FNMPTVLHNLLMTVKKEQDLYNVVFHEVIKETTIDCIERGELLANIRQRYRNLFFKIPEKIKEFHDK*LHEK 891 ++ ++ D+L+K+G++ E P L L VK EQ++YN VFHE+I++ T+ C E+G++LA +RQRY+ L +IP ++K H + + +K Sbjct: 148 ELMKNMDDMLEKAGVDRQNEELSQLSQVGPAPLWLTGL---VKVEQNIYNTVFHELIRQVTVGCAEKGQVLAKLRQRYQALLDRIPRRLKALHTETVAQK 244 HSP 2 Score: 41.5874 bits (96), Expect = 2.501e-17 Identity = 30/100 (30.00%), Postives = 50/100 (50.00%), Query Frame = 3 Query: 876 VVARKILDRRLTEELLRFQNTVSMLSKELSGVKDHEENINQICKQAKLQLKEAVEETKTNADLLREYHDLYEQQRQRLERNVLQLERERDCWRNAAYKIT 1175 VA+K L RRLTEE+ R ++++ S E+ + K + +L + + +L+ YH+LYE R RLE +LQ+ ER+ W + + Sbjct: 240 TVAQKSLGRRLTEEIHRIKSSLHRRSAEI------------LYKNSNCEL---LNDWDPFLSVLQRYHELYELLRTRLEAQLLQMTEERNNWSKLTFSLA 324
BLAST of Sterol O-acyltransferase 1 vs. Planmine SMEST
Match: SMESG000039900.1 (SMESG000039900.1) HSP 1 Score: 1551.57 bits (4016), Expect = 0.000e+0 Identity = 760/762 (99.74%), Postives = 761/762 (99.87%), Query Frame = 3 Query: 876 VVARKILDRRLTEELLRFQNTVSMLSKELSGVKDHEENINQICKQAKLQLKEAVEETKTNADLLREYHDLYEQQRQRLERNVLQLERERDCWRNAAYKITQLVLEHYEIKPAIVLVECESNMISLSQYFVELISVTDNQTLSTIKTKTTQWCNEAQKFALMLAIREENLKTLLNKEIEKINRLKEDFEDDYLSEQGQLIQPINQEETRKILNSVINWEKSMSEICESFGGQSMLMEEEKLKHMKQLCYEYTDIAVEVFNRHRNETDGSLYQEHSALLDINKLIDEMMTQFMDQLTGDNGVADGIIALQTFEENWITRLSNSVAELYFRPLPDSEWIRFKLLLDDWIALLCESKNAIGTTKLNSITVEGASINKRLEIHEIIQSVDNWSQKSSSGIESENLKLREAIINLKKSMIRWTSQVILRLAPDFPDNSPEARRAARLASLGIRELQETAKVLHENISAVSNHIFNCSKDIVTKLMQIKIDTQTEFPDGDSLKLHQLIEFSKSWIEKSEQLLKEIMELEYETQNKMRSEKDTEEMPFVKENSTIDKEKRIEENEIEDYDAGALIGNLLDNVINATSDLFLPEDDNDEDDKIMEVPIPPPTVEGIGVDYNVHSKMLIQDPNEPYSRNKFRNTEPINMPNDLPKTEEAYLLIKIFENLQKRLRSLTVEAMTVEDQCAKKELENEKSKRYLKSLEEIYEKRIIELEQLQTEKKQTLPTPALFNGTSAMERHLSESTNRSTTPKSVTSSKRRAPPHSKRNLKK 3161 VVARKILDRRLTEELLRFQNTVSMLSKELSGVKDHEENINQICKQAKLQLKEAVEETKTNADLLREYHDLYEQQRQRLERNVLQLERERDCWRNAAYKITQLVLEHYEIKPAIVLVECESNMISLSQYFVELISVTDNQTLSTIKTKTTQWCNEAQKFALMLAIREENLKTLLNKEIEKINRLKEDFEDDYLSEQGQLIQPINQEETRKILNSVINWEKSMSEICESFGGQSMLMEEEKLKHMKQLCYEYTDIAVEVFNRHRNETDGSLYQEHSALLDINKLIDEMM QFMDQLTGDNGVADGIIALQTFEENWITRLSNSVAELYFRPLPDSEWIRFKLLLDDWIALLCESKNAIGTTKLNSITVEGASINKRLEIHEIIQSVDNWSQKSSSGIESENLKLREAIINLKKSMIRWTSQVILRLAPDFPDNSPEARRAARLASLGIRELQETAKV+HENISAVSNHIFNCSKDIVTKLMQIKIDTQTEFPDGDSLKLHQLIEFSKSWIEKSEQLLKEIMELEYETQNKMRSEKDTEEMPFVKENSTIDKEKRIEENEIEDYDAGALIGNLLDNVINATSDLFLPEDDNDEDDKIMEVPIPPPTVEGIGVDYNVHSKMLIQDPNEPYSRNKFRNTEPINMPNDLPKTEEAYLLIKIFENLQKRLRSLTVEAMTVEDQCAKKELENEKSKRYLKSLEEIYEKRIIELEQLQTEKKQTLPTPALFNGTSAMERHLSESTNRSTTPKSVTSSKRRAPPHSKRNLKK Sbjct: 273 VVARKILDRRLTEELLRFQNTVSMLSKELSGVKDHEENINQICKQAKLQLKEAVEETKTNADLLREYHDLYEQQRQRLERNVLQLERERDCWRNAAYKITQLVLEHYEIKPAIVLVECESNMISLSQYFVELISVTDNQTLSTIKTKTTQWCNEAQKFALMLAIREENLKTLLNKEIEKINRLKEDFEDDYLSEQGQLIQPINQEETRKILNSVINWEKSMSEICESFGGQSMLMEEEKLKHMKQLCYEYTDIAVEVFNRHRNETDGSLYQEHSALLDINKLIDEMMRQFMDQLTGDNGVADGIIALQTFEENWITRLSNSVAELYFRPLPDSEWIRFKLLLDDWIALLCESKNAIGTTKLNSITVEGASINKRLEIHEIIQSVDNWSQKSSSGIESENLKLREAIINLKKSMIRWTSQVILRLAPDFPDNSPEARRAARLASLGIRELQETAKVIHENISAVSNHIFNCSKDIVTKLMQIKIDTQTEFPDGDSLKLHQLIEFSKSWIEKSEQLLKEIMELEYETQNKMRSEKDTEEMPFVKENSTIDKEKRIEENEIEDYDAGALIGNLLDNVINATSDLFLPEDDNDEDDKIMEVPIPPPTVEGIGVDYNVHSKMLIQDPNEPYSRNKFRNTEPINMPNDLPKTEEAYLLIKIFENLQKRLRSLTVEAMTVEDQCAKKELENEKSKRYLKSLEEIYEKRIIELEQLQTEKKQTLPTPALFNGTSAMERHLSESTNRSTTPKSVTSSKRRAPPHSKRNLKK 1034 HSP 2 Score: 503.827 bits (1296), Expect = 1.692e-160 Identity = 270/272 (99.26%), Postives = 270/272 (99.26%), Query Frame = 1 Query: 61 MEELSIDNVLIKNRLPLLKFKENYSTHSKPAVKPIPAFLSDEILTNLQQCTNALVCPHEGKVSNVWSSVIRREKFKHISDNPICICGAGNDLTFLYDKLPNEIIEHFSDPLINXXXXXXXXXXIEDKMLMRLPEKLDPAEFTLSTHQGMREIQLYDESFTTKPFPHKYHKXXXXXXXXXXXXXXXKIYQSFGDVLDKSGLNEPFEFNMPTVLHNLLMTVKKEQDLYNVVFHEVIKETTIDCIERGELLANIRQRYRNLFFKIPEKIKEFHDK 876 MEELSIDNVLIKNRLPLLKFKENYSTHSKPAVKPIPAFLSDEILTNLQQCTNALVCPHEGKVSNVWSSVIRREKFKHISDNPICICGAGNDLTFLYDKLPNEIIEHFSDPLINSEKSKKRSKKIEDKMLMRLPEKL PAEFTLSTHQGMR IQLYDESFTTKPFPHKYHKISLPIMNPNNISNSNKIYQSFGDVLDKSGLNEPFEFNMPTVLHNLLMTVKKEQDLYNVVFHEVIKETTIDCIERGELLANIRQRYRNLFFKIPEKIKEFHDK Sbjct: 1 MEELSIDNVLIKNRLPLLKFKENYSTHSKPAVKPIPAFLSDEILTNLQQCTNALVCPHEGKVSNVWSSVIRREKFKHISDNPICICGAGNDLTFLYDKLPNEIIEHFSDPLINSEKSKKRSKKIEDKMLMRLPEKLVPAEFTLSTHQGMRAIQLYDESFTTKPFPHKYHKISLPIMNPNNISNSNKIYQSFGDVLDKSGLNEPFEFNMPTVLHNLLMTVKKEQDLYNVVFHEVIKETTIDCIERGELLANIRQRYRNLFFKIPEKIKEFHDK 272
BLAST of Sterol O-acyltransferase 1 vs. Planmine SMEST
Match: SMESG000011832.1 (SMESG000011832.1) HSP 1 Score: 56.9954 bits (136), Expect = 3.797e-12 Identity = 36/145 (24.83%), Postives = 78/145 (53.79%), Query Frame = 3 Query: 876 VVARKILDRRLTEELLRFQNTVSMLSKELSGVKDHEENINQICKQAKLQLKEAVEETKTNADLLREYHDLYEQQRQRLERNVLQLERERDCWRNAAYKITQLVLEHYEIKPAIVLVECESNMISLSQYFVELISVTDNQTLSTIK 1310 V + + D+ LT ++ FQ + L+++L VK+ + + + + +L+ A++++ + +LL EYH LY+ Q+QRL++++ + E++ W + A+ ++ + + + + L + LSQ+F IS D S I+ Sbjct: 222 VKDQTVKDKNLTTQIAEFQMAIRYLTEQLKEVKERDIKVTENAENIHKELESALQDSSRSKELLNEYHVLYDLQKQRLDKHLTVVNNEKEDWSSLAFALSLKISDESLLNTSKRLRLITKKLFQLSQHFAIYISDCDTVLTSKIQ 366 HSP 2 Score: 35.039 bits (79), Expect = 3.797e-12 Identity = 11/45 (24.44%), Postives = 29/45 (64.44%), Query Frame = 1 Query: 733 LYNVVFHEVIKETTIDCIERGELLANIRQRYRNLFFKIPEKIKEF 867 +YN++FHE+ ++ +RG ++ +R +Y +L ++P+++ + Sbjct: 174 IYNIIFHELARQIMSSSEQRGNVVLELRNKYMDLVCQLPKELSKL 218 The following BLAST results are available for this feature:
BLAST of Sterol O-acyltransferase 1 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99) Total hits: 5
BLAST of Sterol O-acyltransferase 1 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99) Total hits: 0
BLAST of Sterol O-acyltransferase 1 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99) Total hits: 0
BLAST of Sterol O-acyltransferase 1 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99) Total hits: 1
BLAST of Sterol O-acyltransferase 1 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99) Total hits: 2
BLAST of Sterol O-acyltransferase 1 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99) Total hits: 4
BLAST of Sterol O-acyltransferase 1 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt) Total hits: 3
BLAST of Sterol O-acyltransferase 1 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL) Total hits: 5
BLAST of Sterol O-acyltransferase 1 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99) Total hits: 1
BLAST of Sterol O-acyltransferase 1 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99) Total hits: 1
BLAST of Sterol O-acyltransferase 1 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46) Total hits: 0
BLAST of Sterol O-acyltransferase 1 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46) Total hits: 2
BLAST of Sterol O-acyltransferase 1 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99) Total hits: 1
BLAST of Sterol O-acyltransferase 1 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST) Total hits: 2
Analyses
This transcript is derived from or has results from the following analyses Sequences
The following sequences are available for this feature:
transcript sequence >SMED30013721 ID=SMED30013721|Name=Sterol O-acyltransferase 1|organism=Schmidtea mediterranea sexual|type=transcript|length=3386bpback to top protein sequence of SMED30013721-orf-1 >SMED30013721-orf-1 ID=SMED30013721-orf-1|Name=SMED30013721-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=273bp MEELSIDNVLIKNRLPLLKFKENYSTHSKPAVKPIPAFLSDEILTNLQQCback to top protein sequence of SMED30013721-orf-2 >SMED30013721-orf-2 ID=SMED30013721-orf-2|Name=SMED30013721-orf-2|organism=Schmidtea mediterranea sexual|type=polypeptide|length=740bp MLSKELSGVKDHEENINQICKQAKLQLKEAVEETKTNADLLREYHDLYEQback to top Annotated Terms
The following terms have been associated with this transcript:
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