Endoglin CD105 antigen

Overview
NameEndoglin CD105 antigen
Smed IDSMED30013709
Length (bp)2477
Neoblast Clusters

Zeng et. al., 2018



▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)



Explore this single cell expression dataset with our NB Cluster Shiny App



 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of Endoglin CD105 antigen (SMED30013709) t-SNE clustered cells

Violin plots show distribution of expression levels for Endoglin CD105 antigen (SMED30013709) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of Endoglin CD105 antigen (SMED30013709) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for Endoglin CD105 antigen (SMED30013709) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020



SMED30013709

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 7

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
head regionSMED30013709SMESG000039228.1 SMESG000013245.1 SmedASXL_012021SmedAsxl_ww_GCZZ01PMID:27034770
Currie et al., 2016		whole organism asexual adult RNA-sequencing evidence
head regionSMED30013709SMESG000039228.1 SmedASXL_005104SmedAsxl_ww_GCZZ01PMID:27034770
Currie et al., 2016		whole organism asexual adult RNA-sequencing evidence
nervous systemSMED30013709SMESG000039228.1 SMESG000013245.1 dd_Smed_v4_13730_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
cephalic gangliaSMED30013709SMESG000039228.1 SMESG000013245.1 dd_Smed_v4_13730_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
parenchymal cellSMED30013709SMESG000039228.1 SMESG000013245.1 dd_Smed_v4_13730_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
Smed sexual biotypeSMED30013709SMESG000039228.1 Contig24987newmark_estsPMID:29674431
Fincher et al., 2018		FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
head regionSMED30013709SMESG000039228.1 SMESG000013245.1 dd_Smed_v6_13730_0_1dd_Smed_v6PMID:28171748
Stückemann et al., 2017		whole organism asexual adult RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
[Close]
BLAST of Endoglin CD105 antigen vs. TrEMBL
Match: A0A5K4F052 (Uncharacterized protein OS=Schistosoma mansoni OX=6183 PE=4 SV=1)

HSP 1 Score: 389.423 bits (999), Expect = 6.541e-116
Identity = 242/626 (38.66%), Postives = 326/626 (52.08%), Query Frame = 2 
Query:  206 GSCVGKPSDFCSKQVDNSICNDEKNECFCKRGFVAIREEEDKVSCKTLLTDLKCRMDRDCNHVNSSTCHPGAGYCSCPGHTIYSSELHACRVKTFQIENNQFCLVCRNEGGVCFFYKDYDKKTAYIRADNSYVGCACPMKRFPI----SDIKHEICNNNLVDIGDYCDDNKDICRSKKAICA---EKSL--NNQ------------------------IKICVCPKGYIKLYQSNLHYHECFPILNENSPLCSLCAASKGTCYDINDDDVGDGCICPSMYSTAETQIEFKHQNQ--FCTISHLESNCKNNILKVCYKPHSQPPYDYLKDDLINKNAIIRL-------------IGGSDFKANSE---------CFL-----------NFVEDE-------------NQFCINIDLLEQIRECGIRSYKIAHRKLQYEFILEVLSNKSFKTPSKDMQFPLSCITKEPE---SAIKTYQTSTKSNQDIKNSIRKQKDKFNLGLQVLDNNNNEIESVEEGSIIKLDLSLIDTKGKYKAISVEQCYFSNYST-IDYADSLSDKSVLLIKKGCPNVREGFMANFRSRIMPGIHIQSDGFHAFKLTTDSNILFIDCFIKVCINEANCWQIDC 1828
            G+C    S FCS+QV+NS+CN EKNECFC++GFVAIRE   +V+CKTLLTDLKCR+DRDC HVN S+CHPGAGYCSCPG+TIY  E HACR + F   ++ FC VC    G CF Y+ +++     R + + VGC CP  +  I    SD    +C+ NLVDIG  CDD    CRS  ++C    E+ L   NQ                        I+ C C  GY+ +YQ NL Y+ECF IL   +  C  C  + G CYD+NDD +GDGC CP   S+    I +  +N   +C   H+  NC N  L VCY PH+  PY  L DDL+N  +++RL             I G   +AN           C L            FV +               +FC+NID+  +   CGIR YK++H  +QYE ILEVL N S +TPS+D   PL CI++ P    + I      T    ++ N+    +    + L++L+ NN EI S   GS ++LD  L +  G YK I+ E CY +N S   DY    SD S LLI   C + +    A F S  +   H+Q++ F AF+L  +  ++F  C  ++C    +C Q  C
Sbjct:   37 GACTQYDSGFCSRQVENSVCNHEKNECFCRKGFVAIREN-GRVTCKTLLTDLKCRVDRDCVHVNRSSCHPGAGYCSCPGNTIYVPEKHACRAR-FTYPSDPFCDVCLQLKGTCFKYELFERVITDQRVNPNGVGCVCPDHKVSISTRTSDPLKYMCDGNLVDIGSECDDESLFCRSINSVCKPLQEELLLSTNQLHSFKSNLWSENFPSGDHLRRSQIIRTCQCKPGYLPVYQINLKYNECFKILPMKAKYCQKCVDTGGQCYDLNDDGIGDGCDCPPSLSS----IIYGKENSEIYCGTVHVSVNCTNGYLSVCYYPHTYGPYSNLFDDLMNHRSVVRLASDNYLTDTLPLQISGLSSEANRTYHYSNFQNLCILKSENDTIDIGNTFVTESISHDNYHLHGAQTKRFCLNIDVWRKNGLCGIRLYKLSHDTVQYEGILEVLVNTSIRTPSRDKIIPLKCISRTPNRPMNEINDGNLQTIGTMNLANTPTHPQ----ISLRILNENNKEIPSTFVGSRVRLDALLFNPSGSYKHIAAEYCYGNNRSLHSDYFS--SDTSTLLIDHRCLHKKPLLTAKFSSIGLLNGHLQTEIFQAFRL-GNMTLVFFTCVFRICQLSTDCEQTRC 649
[Close]
BLAST of Endoglin CD105 antigen vs. TrEMBL
Match: A0A4E0RJA6 (ZP domain-containing protein OS=Fasciola hepatica OX=6192 GN=D915_000016 PE=4 SV=1)

HSP 1 Score: 385.956 bits (990), Expect = 3.076e-115
Identity = 234/686 (34.11%), Postives = 337/686 (49.13%), Query Frame = 2 
Query:  185 DEHVVFAGSCVGKPSDFCSKQVDNSICNDEKNECFCKRGFVAIREEEDKVSCKTLLTDLKCRMDRDCNHVNSSTCHPGAGYCSCPGHTIYSSELHACRVKTFQIENNQFCLVCRNEGGVCFFYKDYDKKTAYIRADNSYVGCACPMKRFPIS----DIKHEICNNNLVDIGDYCDDNKDICRSKKAICAEKSLNNQ------------------------------IKICVCPKGYIKLYQSNLHYHECFPILNENSPLCSLCAASKGTCYDINDDDVGDGCICPSMYSTAETQIEFKHQNQFCTISHLESNCKNNILKVCYKPHSQPPYDYLKDDLINKNAIIRLI--------------------GGSDFKANS-----ECFLNFVED------------------------ENQFCINIDLLEQIRECGIRSYKI--------AHRKLQYEFILEVLSNKSFKTPSKDMQFPLSCITKEPESAIKTYQTSTKSNQDIKNSIRKQ-KDKFNLGLQVLDNNNNEIESVEEGSIIKLDLSLIDTKGKYKAISVEQCYFSNYSTIDYADSLSDKSVLLIKKGCPNVREGFMANFRSRIMPGIHIQSDGFHAFKLTTDSNILFIDCFIKVCINEANCWQI--DCNKSPQQ------ISQPKDDKSNYVIVRRRTQLNILKKRRFTNTK 1942
            +EH+V++G+C    + FCS+QV+NS+CN  KNECFCK+ FVAIRE   +V+CKTLLTDLKCR+DRDC HVN S+CHPGAGYCSCPG+TIY  + HACR +      +  C  C+ + G CF Y+ ++      R + S +GC CP  + P+          IC+  LVD+G  CD    +CRSK+AIC   S                                   +IC C    + +YQS L Y ECFP L   +  C  C AS G CYD+N+D VGDGC+CP   S          Q+  CT   +  NC +  L VCY+PHS PPY++L  DL    A+ +L+                      SD  A S      C LN +E                         + Q C++ D+ +  + CG+R Y++            +QYE +LE++ N++ +TP+KD Q PL CI+  P           K    +   +RK  K   +L  +V++  N EI + + G+ I+LD  L+D+ G+YK ++VE+C + N ST   +D+ S K V  I KGCP         F +   P  H+QS  F AF+  T  + LF  C  ++C++   C+Q    C+    Q       + PK D   +  +   T  ++L   R+T+ +
Sbjct:   34 NEHLVYSGACALYDTQFCSRQVENSVCNKVKNECFCKKDFVAIREN-GRVTCKTLLTDLKCRVDRDCIHVNRSSCHPGAGYCSCPGNTIYVPQQHACRTRV-SYNQDSVCKSCQLQNGSCFLYESFELSDVEKRFNPSRIGCVCPDGKIPVGMQFDGWTKNICSGKLVDMGFECDQKHAVCRSKRAICDSVSTQTSRSFSPHKVPANFLWPNIVDYSSMANGEQGPKRICQCQNTMVAVYQSTLGYTECFPQLGPKAAQCHSCIASGGLCYDLNNDGVGDGCVCPPHKSLGSKLRSTGEQS--CTGLQVSLNCSDGHLSVCYRPHSAPPYEHLATDLTEGKAVAQLVPTNAENMAVFHEYMNEEKNATSSDTDARSLQFRDPCQLNKMESNLARLSNQMDGFTGPHSTGLDQSIQEQHCVHFDVWQMKQTCGVRIYRLNVSSFISYVENAVQYEALLEIMVNRTRRTPNKDFQIPLKCISPPP-----------KRMPTLDYHLRKTVKQSADLEFRVVNKENREIYATQIGTTIRLDALLLDSSGQYKVLTVEKCQYGNRSTSHTSDA-SHKMVPFIYKGCPLTNAKVQIPFTNGQYPSDHVQSAPFPAFREGTLFS-LFFKCVFQLCVDPQQCFQASPSCDSGHAQDSDHVTATDPKSDTRTW--MNGSTSSSVLLVERWTHVE 700
[Close]
BLAST of Endoglin CD105 antigen vs. TrEMBL
Match: A0A5K4F1C8 (Uncharacterized protein OS=Schistosoma mansoni OX=6183 PE=4 SV=1)

HSP 1 Score: 386.726 bits (992), Expect = 8.885e-115
Identity = 241/625 (38.56%), Postives = 325/625 (52.00%), Query Frame = 2 
Query:  209 SCVGKPSDFCSKQVDNSICNDEKNECFCKRGFVAIREEEDKVSCKTLLTDLKCRMDRDCNHVNSSTCHPGAGYCSCPGHTIYSSELHACRVKTFQIENNQFCLVCRNEGGVCFFYKDYDKKTAYIRADNSYVGCACPMKRFPI----SDIKHEICNNNLVDIGDYCDDNKDICRSKKAICA---EKSL--NNQ------------------------IKICVCPKGYIKLYQSNLHYHECFPILNENSPLCSLCAASKGTCYDINDDDVGDGCICPSMYSTAETQIEFKHQNQ--FCTISHLESNCKNNILKVCYKPHSQPPYDYLKDDLINKNAIIRL-------------IGGSDFKANSE---------CFL-----------NFVEDE-------------NQFCINIDLLEQIRECGIRSYKIAHRKLQYEFILEVLSNKSFKTPSKDMQFPLSCITKEPE---SAIKTYQTSTKSNQDIKNSIRKQKDKFNLGLQVLDNNNNEIESVEEGSIIKLDLSLIDTKGKYKAISVEQCYFSNYST-IDYADSLSDKSVLLIKKGCPNVREGFMANFRSRIMPGIHIQSDGFHAFKLTTDSNILFIDCFIKVCINEANCWQIDC 1828
            +C    S FCS+QV+NS+CN EKNECFC++GFVAIRE   +V+CKTLLTDLKCR+DRDC HVN S+CHPGAGYCSCPG+TIY  E HACR + F   ++ FC VC    G CF Y+ +++     R + + VGC CP  +  I    SD    +C+ NLVDIG  CDD    CRS  ++C    E+ L   NQ                        I+ C C  GY+ +YQ NL Y+ECF IL   +  C  C  + G CYD+NDD +GDGC CP   S+    I +  +N   +C   H+  NC N  L VCY PH+  PY  L DDL+N  +++RL             I G   +AN           C L            FV +               +FC+NID+  +   CGIR YK++H  +QYE ILEVL N S +TPS+D   PL CI++ P    + I      T    ++ N+    +    + L++L+ NN EI S   GS ++LD  L +  G YK I+ E CY +N S   DY    SD S LLI   C + +    A F S  +   H+Q++ F AF+L  +  ++F  C  ++C    +C Q  C
Sbjct:   50 ACTQYDSGFCSRQVENSVCNHEKNECFCRKGFVAIREN-GRVTCKTLLTDLKCRVDRDCVHVNRSSCHPGAGYCSCPGNTIYVPEKHACRAR-FTYPSDPFCDVCLQLKGTCFKYELFERVITDQRVNPNGVGCVCPDHKVSISTRTSDPLKYMCDGNLVDIGSECDDESLFCRSINSVCKPLQEELLLSTNQLHSFKSNLWSENFPSGDHLRRSQIIRTCQCKPGYLPVYQINLKYNECFKILPMKAKYCQKCVDTGGQCYDLNDDGIGDGCDCPPSLSS----IIYGKENSEIYCGTVHVSVNCTNGYLSVCYYPHTYGPYSNLFDDLMNHRSVVRLASDNYLTDTLPLQISGLSSEANRTYHYSNFQNLCILKSENDTIDIGNTFVTESISHDNYHLHGAQTKRFCLNIDVWRKNGLCGIRLYKLSHDTVQYEGILEVLVNTSIRTPSRDKIIPLKCISRTPNRPMNEINDGNLQTIGTMNLANTPTHPQ----ISLRILNENNKEIPSTFVGSRVRLDALLFNPSGSYKHIAAEYCYGNNRSLHSDYFS--SDTSTLLIDHRCLHKKPLLTAKFSSIGLLNGHLQTEIFQAFRL-GNMTLVFFTCVFRICQLSTDCEQTRC 661
[Close]
BLAST of Endoglin CD105 antigen vs. TrEMBL
Match: A0A183MJ20 (Uncharacterized protein OS=Schistosoma margrebowiei OX=48269 GN=SMRZ_LOCUS16045 PE=4 SV=1)

HSP 1 Score: 374.015 bits (959), Expect = 4.893e-110
Identity = 242/644 (37.58%), Postives = 329/644 (51.09%), Query Frame = 2 
Query:  182 TDEHVVFAGSCVGKPSDFCSKQVDNSICNDEKNECFCKRGFVAIREEEDKVSCKTLLTDLKCRMDRDCNHVNSSTCHPGAGYCSCPGHTIYSSELHACRVKTFQIENNQFCLVCRNEGGVCFFYKDYDKKTAYIRADNSYVGCACPMKRFPI----SDIKHEICNNNLVDIGDYCDDNKDICRSKKAIC---AEKSL--NNQ------------------------IKICVCPKGYIKLYQSNLHYHECFPILNENSPLCSLCAASKGTCYDINDDDVGDGCICPSMYSTAETQIEFKHQNQ--FCTISH-------------LESNCKNNILKVCYKPHSQPPYDYLKDDLINKNAIIRL-------------IGGSDFKAN-SECFLNF-----VEDEN---------------------------QFCINIDLLEQIRECGIRSYKIAHRKLQYEFILEVLSNKSFKTPSKDMQFPLSCITKEPESAIKTYQTSTKSNQDIKNSIRKQKDKFNLGLQVLDNNNNEIESVEEGSIIKLDLSLIDTKGKYKAISVEQCYFSNYST-IDYADSLSDKSVLLIKKGCPNVREGFMANFRSRIMPGIHIQSDGFHAFKLTTDSNILFIDCFIKVCINEANCWQIDC 1828
            T++H+V++G+C    S+FCS+QV+NS+CN EKNECFC++GFVAIRE   +V+CKTLLTDLKCR+DRDC HVN S+CHPGAGYCSCPG+TIY  E HACR + F   ++ FC VC    G CF Y+ +++ T   R + + VGC CP  +  I    SD    +C+ NLVDIG  CDD    CRS  +IC    E+ L  NNQ                        I+ C C  GY+ +YQ NL Y+ECF IL   +  C  C  + G CYD+NDD +GDGC CP   S+    I +  +N   +C   H             +  NC N  L VCY PH+  PY  L DDLIN  ++ RL             I G   + N +  + NF     ++ EN                           +FC+N+D+  +   CGIR YK++H  +QYE ILEVL N S +TPS+D   P+ CI++ P   +              N +        + L++L+  N EI S   GS I+LD  L      YK I+ E CY +N S   DY    SD   LLI   C + +    A F S  +   H+Q++ F AF+L  +  ++F  C  ++C    +C Q  C
Sbjct:   24 TNDHLVYSGACSQYDSNFCSRQVENSVCNYEKNECFCRKGFVAIREN-GRVTCKTLLTDLKCRVDRDCVHVNRSSCHPGAGYCSCPGNTIYVPEKHACRSR-FTYPSDPFCDVCLQLKGTCFKYELFERVTTEERVNPNGVGCVCPDHKVSISTRTSDPLKYMCDGNLVDIGSECDDESLFCRSINSICKPLQEELLLSNNQLHSIKSNLWSENFPSGDHLRRSQIIRTCQCKPGYLPVYQINLKYNECFKILPMKAKHCQKCVDTGGQCYDLNDDGIGDGCDCPPSLSS----IVYGKENSEIYCGTVHGTCNYDYFNFHVLVSVNCTNGYLSVCYYPHTYGPYSSLFDDLINYRSVARLASDNYMIDTLPLQISGLSSETNRTYHYSNFQNLCTLKSENDTTDTANTFVTESISHDNFHLHGSQTKRFCLNVDVWRKNGLCGIRLYKLSHDTVQYEGILEVLVNTSIRTPSRDKIIPIKCISRIPNRPMNKISVGNPQTFGTMNLVNTPAHP-QISLRILNERNKEILSAFVGSHIRLDALL----RSYKHIAAEYCYGNNRSLHSDYFS--SDIGTLLIDHRCLHKKPLLTAKFSSIGLLNGHLQTELFQAFRL-GNMTLVFFTCVFRICQLPTDCEQTKC 653
[Close]
BLAST of Endoglin CD105 antigen vs. TrEMBL
Match: A0A4Z2CXR8 (Endoglin antigen OS=Schistosoma japonicum OX=6182 GN=EWB00_006519 PE=4 SV=1)

HSP 1 Score: 370.548 bits (950), Expect = 5.698e-109
Identity = 242/635 (38.11%), Postives = 331/635 (52.13%), Query Frame = 2 
Query:  182 TDEHVVFAGSCVGKPSDFCSKQVDNSICNDEKNECFCKRGFVAIREEEDKVSCKTLLTDLKCRMDRDCNHVNSSTCHPGAGYCSCPGHTIYSSELHACRVKTFQIENNQFCLVCRNEGGVCFFYKDYDKKTAYIRADNSYVGCACPMKRFPI----SDIKHEICNNNLVDIGDYCDDNKDICRSKKAICA---EKSL--------------------------NNQIKICVCPKGYIKLYQSNLHYHECFPILNENSPLCSLCAASKGTCYDINDDDVGDGCICPSMYSTAETQIEFKHQNQ--FCTISHLESNCKNNILKVCYKPHSQPPYDYLKDDLINKNAIIRLIGGS-----------------------DFKANSECFLNFVED----EN--------------------QFCINIDLLEQIRECGIRSYKIAHRKLQYEFILEVLSNKSFKTPSKDMQFPLSCITKEPESAIKTYQTSTKSNQDIKNSIRKQKDKFN---LGLQVLDNNNNEIESVEEGSIIKLDLSLIDTKGKYKAISVEQCYFSNYST-IDYADSLSDKSVLLIKKGCPNVREGFMANFRSRIMPGIHIQSDGFHAFKLTTDSNILFIDCFIKVCINEANCWQIDC 1828
            T++H+V++G+C      FCS+QV+NS+CN EKNECFC++GFVAIRE   +V+CKTLLTDLKCR+DRDC HVN S+CHPGAGYCSCPG+TIY  E HACR + F   N+ FC VC    G CF Y+ +D+     R + + VGC CP  R  I    SD    +C+ NLVDIG  CDD    CRS  ++C    E+ L                          N  I+ C+C  GY+ +YQ NL Y+ECF IL   +  C  C  + G CYD++DD  GDGC CP   S+    I +  +N   FC  +H+  NC +    VCY PHS  PY  L +DL+N  +++RL  GS                            S C L    D    EN                    +FC+N+D+  Q   CGIR YK+    +QYE ILEVL N S +TPSKD   PL CI++ P   +     + ++ + + +S     D F    + L++L+  N EI S   G  I+LD  LID  G YK I+ E CY +N S  ++Y  S+S+   LLI   C   +    A F +  +   H+Q++ F AF+L   +++ F  C  ++C    +C Q +C
Sbjct:   24 TNDHLVYSGACSQYDLGFCSRQVENSVCNHEKNECFCRKGFVAIREN-GRVTCKTLLTDLKCRVDRDCVHVNRSSCHPGAGYCSCPGNTIYVPEKHACRSR-FIYPNDPFCDVCLQLKGTCFKYELFDRVVTDQRVNPNGVGCVCPDHRVSINTRTSDPLKYMCDGNLVDIGSECDDESLFCRSINSVCKPVQEELLLSSTQLYSIPSSLWSENFPSGDPLRRNQIIRTCMCKPGYLPVYQINLKYNECFKILPMKAKRCQKCVDTGGQCYDLDDDGTGDGCDCPPSLSS----IVYGKENSEIFCGTAHVSVNCTDGHFTVCYYPHSYGPYKNLFEDLVNYRSVVRLASGSYSTETIPRQTLVSLLNSVNATYRSANFQSSCMLKLENDTTDNENTFETDSFSFGNHHLHGKQSRRFCLNVDVWRQNGLCGIRLYKLGRDTVQYEGILEVLVNNSIRTPSKDKIIPLKCISRIPNRPMNKINENLQALETMSSS-----DTFTHPQISLRILNEKNKEILSAFVGLRIRLDALLIDPPGPYKYIAAEYCYGNNRSVHLNY--SISETGTLLIDHRCSPRKTLLSAKFSNNGLLNGHLQTEIFQAFRLGNMTSVFFT-CVFRLCQLSKDCEQAEC 644
[Close]
BLAST of Endoglin CD105 antigen vs. Planmine SMEST
Match: SMESG000039228.1 (SMESG000039228.1)

HSP 1 Score: 1503.42 bits (3891), Expect = 0.000e+0
Identity = 745/746 (99.87%), Postives = 746/746 (100.00%), Query Frame = 2 
Query:  206 GSCVGKPSDFCSKQVDNSICNDEKNECFCKRGFVAIREEEDKVSCKTLLTDLKCRMDRDCNHVNSSTCHPGAGYCSCPGHTIYSSELHACRVKTFQIENNQFCLVCRNEGGVCFFYKDYDKKTAYIRADNSYVGCACPMKRFPISDIKHEICNNNLVDIGDYCDDNKDICRSKKAICAEKSLNNQIKICVCPKGYIKLYQSNLHYHECFPILNENSPLCSLCAASKGTCYDINDDDVGDGCICPSMYSTAETQIEFKHQNQFCTISHLESNCKNNILKVCYKPHSQPPYDYLKDDLINKNAIIRLIGGSDFKANSECFLNFVEDENQFCINIDLLEQIRECGIRSYKIAHRKLQYEFILEVLSNKSFKTPSKDMQFPLSCITKEPESAIKTYQTSTKSNQDIKNSIRKQKDKFNLGLQVLDNNNNEIESVEEGSIIKLDLSLIDTKGKYKAISVEQCYFSNYSTIDYADSLSDKSVLLIKKGCPNVREGFMANFRSRIMPGIHIQSDGFHAFKLTTDSNILFIDCFIKVCINEANCWQIDCNKSPQQISQPKDDKSNYVIVRRRTQLNILKKRRFTNTKKQNKVTFGKCTYAVCLTALQTSVMAAXXXXXXXXXXXXXXXXYRKNRLYQEQNKMAHHCLNEHNQSFYSRHQHSETKTHPVRHRCISLAMRSIDDINENSLRTIPQSDFLPTPIHRFQLVNDYEMENSSAINQNNPSFIPLTSTVQRTPNVKVAHQSQSQAETVTRV 2443
            GSCVGKPSDFCSKQVDNSICNDEKNECFCKRGFVAIREEEDKVSCKTLLTDLKCRMDRDCNHVNSSTCHPGAGYCSCPGHTIYSSELHACRVKTFQIENNQFCLVCRNEGGVCFFYKDYDKKTAYIRADNSYVGCACPMKRFPISDIKHEICNNNLVDIGDYCDDNKDICRSKKAICAEKS+NNQIKICVCPKGYIKLYQSNLHYHECFPILNENSPLCSLCAASKGTCYDINDDDVGDGCICPSMYSTAETQIEFKHQNQFCTISHLESNCKNNILKVCYKPHSQPPYDYLKDDLINKNAIIRLIGGSDFKANSECFLNFVEDENQFCINIDLLEQIRECGIRSYKIAHRKLQYEFILEVLSNKSFKTPSKDMQFPLSCITKEPESAIKTYQTSTKSNQDIKNSIRKQKDKFNLGLQVLDNNNNEIESVEEGSIIKLDLSLIDTKGKYKAISVEQCYFSNYSTIDYADSLSDKSVLLIKKGCPNVREGFMANFRSRIMPGIHIQSDGFHAFKLTTDSNILFIDCFIKVCINEANCWQIDCNKSPQQISQPKDDKSNYVIVRRRTQLNILKKRRFTNTKKQNKVTFGKCTYAVCLTALQTSVMAALLVTLIILIIFIILVIYRKNRLYQEQNKMAHHCLNEHNQSFYSRHQHSETKTHPVRHRCISLAMRSIDDINENSLRTIPQSDFLPTPIHRFQLVNDYEMENSSAINQNNPSFIPLTSTVQRTPNVKVAHQSQSQAETVTRV
Sbjct:   46 GSCVGKPSDFCSKQVDNSICNDEKNECFCKRGFVAIREEEDKVSCKTLLTDLKCRMDRDCNHVNSSTCHPGAGYCSCPGHTIYSSELHACRVKTFQIENNQFCLVCRNEGGVCFFYKDYDKKTAYIRADNSYVGCACPMKRFPISDIKHEICNNNLVDIGDYCDDNKDICRSKKAICAEKSMNNQIKICVCPKGYIKLYQSNLHYHECFPILNENSPLCSLCAASKGTCYDINDDDVGDGCICPSMYSTAETQIEFKHQNQFCTISHLESNCKNNILKVCYKPHSQPPYDYLKDDLINKNAIIRLIGGSDFKANSECFLNFVEDENQFCINIDLLEQIRECGIRSYKIAHRKLQYEFILEVLSNKSFKTPSKDMQFPLSCITKEPESAIKTYQTSTKSNQDIKNSIRKQKDKFNLGLQVLDNNNNEIESVEEGSIIKLDLSLIDTKGKYKAISVEQCYFSNYSTIDYADSLSDKSVLLIKKGCPNVREGFMANFRSRIMPGIHIQSDGFHAFKLTTDSNILFIDCFIKVCINEANCWQIDCNKSPQQISQPKDDKSNYVIVRRRTQLNILKKRRFTNTKKQNKVTFGKCTYAVCLTALQTSVMAALLVTLIILIIFIILVIYRKNRLYQEQNKMAHHCLNEHNQSFYSRHQHSETKTHPVRHRCISLAMRSIDDINENSLRTIPQSDFLPTPIHRFQLVNDYEMENSSAINQNNPSFIPLTSTVQRTPNVKVAHQSQSQAETVTRV 791
[Close]
BLAST of Endoglin CD105 antigen vs. Planmine SMEST
Match: SMESG000039228.1 (SMESG000039228.1)

HSP 1 Score: 915.605 bits (2365), Expect = 0.000e+0
Identity = 445/447 (99.55%), Postives = 446/447 (99.78%), Query Frame = 2 
Query:  206 GSCVGKPSDFCSKQVDNSICNDEKNECFCKRGFVAIREEEDKVSCKTLLTDLKCRMDRDCNHVNSSTCHPGAGYCSCPGHTIYSSELHACRVKTFQIENNQFCLVCRNEGGVCFFYKDYDKKTAYIRADNSYVGCACPMKRFPISDIKHEICNNNLVDIGDYCDDNKDICRSKKAICAEKSLNNQIKICVCPKGYIKLYQSNLHYHECFPILNENSPLCSLCAASKGTCYDINDDDVGDGCICPSMYSTAETQIEFKHQNQFCTISHLESNCKNNILKVCYKPHSQPPYDYLKDDLINKNAIIRLIGGSDFKANSECFLNFVEDENQFCINIDLLEQIRECGIRSYKIAHRKLQYEFILEVLSNKSFKTPSKDMQFPLSCITKEPESAIKTYQTSTKSNQDIKNSIRKQKDKFNLGLQVLDNNNNEIESVEEGSIIKLDLSLIDTKG 1546
            GSCVGKPSDFCSKQVDNSICNDEKNECFCKRGFVAIREEEDKVSCKTLLTDLKCRMDRDCNHVNSSTCHPGAGYCSCPGHTIYSSELHACRVKTFQIENNQFCLVCRNEGGVCFFYKDYDKKTAYIRADNSYVGCACPMKRFPISDIKHEICNNNLVDIGDYCDDNKDICRSKKAICAEKS+NNQIKICVCPKGYIKLYQSNLHYHECFPILNENSPLCSLCAASKGTCYDINDDDVGDGCICPSMYSTAETQIEFKHQNQFCTISHLESNCKNNILKVCYKPHSQPPYDYLKDDLINKNAIIRLIGGSDFKANSECFLNFVEDENQFCINIDLLEQIRECGIRSYKIAHRKLQYEFILEVLSNKSFKTPSKDMQFPLSCITKEPESAIKTYQTSTKSNQDIKNSIRKQKDKFNLGLQVLDNNNNEIESVEEGSIIKLDLSLIDTK 
Sbjct:   46 GSCVGKPSDFCSKQVDNSICNDEKNECFCKRGFVAIREEEDKVSCKTLLTDLKCRMDRDCNHVNSSTCHPGAGYCSCPGHTIYSSELHACRVKTFQIENNQFCLVCRNEGGVCFFYKDYDKKTAYIRADNSYVGCACPMKRFPISDIKHEICNNNLVDIGDYCDDNKDICRSKKAICAEKSMNNQIKICVCPKGYIKLYQSNLHYHECFPILNENSPLCSLCAASKGTCYDINDDDVGDGCICPSMYSTAETQIEFKHQNQFCTISHLESNCKNNILKVCYKPHSQPPYDYLKDDLINKNAIIRLIGGSDFKANSECFLNFVEDENQFCINIDLLEQIRECGIRSYKIAHRKLQYEFILEVLSNKSFKTPSKDMQFPLSCITKEPESAIKTYQTSTKSNQDIKNSIRKQKDKFNLGLQVLDNNNNEIESVEEGSIIKLDLSLIDTKA 492
[Close]
BLAST of Endoglin CD105 antigen vs. Planmine SMEST
Match: SMESG000020512.1 (SMESG000020512.1)

HSP 1 Score: 476.478 bits (1225), Expect = 4.711e-156
Identity = 259/617 (41.98%), Postives = 376/617 (60.94%), Query Frame = 2 
Query:  185 DEHVVFAGSCVGKPSDFCSKQVDNSICNDEKNECFCKRGFVAIREEEDKVSCKTLLTDLKCRMDRDCNHVNSSTCHPGAGYCSCPGHTIYSSELHACRVKTFQIENNQFCLVCRNEGGVCFFYKDYDKKTAYIRADNSYVGCACPMK-RFPISDIKH--EICNNNLVDIGDYCDDNKDICRSKKAICAE-KSLNNQIKICVCPKGYIKLYQSNLHYHECFPILNENSPLCSLCAASKGTCYDINDDDVGDGCICPSMYSTAETQIEFKHQNQFCTISHLESNCKNNILKVCYKPHSQPPYDYLKDDLINKNAIIRLIGGSDFKANSECFLNFVEDENQFCINIDLLEQIRECGIRSYKIAHRKLQYEFILEVLSNKSFKTPSKDMQFPLSCITKEPESAIKTYQTSTKSNQDIKNSIRKQKDKFNLGLQVLDNNNNEIESVEEGSIIKLDLSLIDTKGKYKAISVEQCYFSNYSTIDYADSLSDKSVLLIKKGCPNVREGFMANFRSRIMPGIHIQSDGFHAFKLTTDSNILFIDCFIKVCINEANCWQIDCNKSPQQISQPKDDK------SNYVIVRRRTQLNILKKRRFTNTKKQNKVTFGKCTYAVCLTALQT 2005
            + H    GSC+GK  ++CS+QV+NSICN  KNECFCK+G+VAIREE D+V+CKTLLT+LKCR+D DC H+N STCHPGAG C+CPG+T+YS ELHACR + F  + N FCL C+   GVCF Y + D  +   +    ++GCAC       I++ K   ++C   L DIG++CD+ +  C+SK A C      N+  ++C C    + +YQS+LHY ECFP L++  P C  C    G CYD+N+DD+GDGCICPS  S+  + ++F+   Q C  + +   C N  L +CY+PH++PPY++L  DL +  + + L+  +D K N    L  +   N++CI IDLL+    CG++ +K+   KL Y+  LEV  +++ K PSKD+  P+SCI+   +  IK    +  S   I      + +  NLGLQVLD  N E+ S+ EGS IK DLSL+D++GK++ + VE+CY SN+ST+ + +  S+    +I KGCP    GF A F++ + PGIH+QSD F  F+     +I F  CFIKVC++  +C  + C    Q++    +DK      S  VI +R T + + K + + NTK     +   C + VCL+A QT
Sbjct:   19 NSHRYPKGSCIGKSENYCSEQVENSICNRLKNECFCKKGYVAIREE-DRVTCKTLLTNLKCRVDSDCMHINRSTCHPGAGQCACPGNTVYSIELHACRSR-FSEDQNPFCLTCQQLNGVCFKYDNGDNTSVSFKYKTEFIGCACSRNYATSITNYKKFSDLCRTTLSDIGEFCDNKQYFCQSKYAECRTINEENSSHRLCHCASDKVPVYQSHLHYFECFPKLSKTHPNCLSCHNLNGHCYDMNNDDIGDGCICPSRLSSETSNLDFQSNLQLCKTNTVHEQCSNGYLSICYQPHTEPPYEHLSHDLESNISTVNLVNRNDDKCN----LQKIASYNKYCIRIDLLDFSYNCGVQMHKLKFGKLLYQATLEVRLDRNIKQPSKDLVIPVSCISDHFQREIKNQSENLSSVIKI-----PEANILNLGLQVLDKFNKEVFSLVEGSEIKFDLSLVDSQGKFRGMRVEECYTSNHSTVIH-EKKSNYGDKIISKGCPIFSNGFFAPFKTFVSPGIHLQSDLFQVFRHGNLHSI-FYKCFIKVCVDVKDCENVKCYN--QELKYQSEDKQHLKNNSKSVIFKRWTHIEVQKLQGYKNTKPGTDNSV--CHHVVCLSASQT 618
[Close]
BLAST of Endoglin CD105 antigen vs. Planmine SMEST
Match: SMESG000020512.1 (SMESG000020512.1)

HSP 1 Score: 464.537 bits (1194), Expect = 4.043e-151
Identity = 259/637 (40.66%), Postives = 376/637 (59.03%), Query Frame = 2 
Query:  185 DEHVVFAGSCVGKPSDFCSKQVDNSICNDEKNECFCKRGFVAIREEEDKVSCKTLLTDLKCRMDRDCNHVNSSTCHPGAGYCSCPGHTIYSSELHACRVKTFQIENNQFCLVCRNEGGVCFFYKDYDKKTAYIRADNSYVGCACPMK-RFPISDIKH--EICNNNLVDIGDYCDDNKDICRSKKAICAE-KSLNNQIKICVCPKGYIKLYQSNLHYHECFPILNENSPLCSLCAASKGTCYDINDDDVGDGCICPSMYSTAETQIEFKHQNQFCTIS--------------------HLESNCKNNILKVCYKPHSQPPYDYLKDDLINKNAIIRLIGGSDFKANSECFLNFVEDENQFCINIDLLEQIRECGIRSYKIAHRKLQYEFILEVLSNKSFKTPSKDMQFPLSCITKEPESAIKTYQTSTKSNQDIKNSIRKQKDKFNLGLQVLDNNNNEIESVEEGSIIKLDLSLIDTKGKYKAISVEQCYFSNYSTIDYADSLSDKSVLLIKKGCPNVREGFMANFRSRIMPGIHIQSDGFHAFKLTTDSNILFIDCFIKVCINEANCWQIDCNKSPQQISQPKDDK------SNYVIVRRRTQLNILKKRRFTNTKKQNKVTFGKCTYAVCLTALQT 2005
            + H    GSC+GK  ++CS+QV+NSICN  KNECFCK+G+VAIREE D+V+CKTLLT+LKCR+D DC H+N STCHPGAG C+CPG+T+YS ELHACR + F  + N FCL C+   GVCF Y + D  +   +    ++GCAC       I++ K   ++C   L DIG++CD+ +  C+SK A C      N+  ++C C    + +YQS+LHY ECFP L++  P C  C    G CYD+N+DD+GDGCICPS  S+  + ++F+   Q C  +                     +   C N  L +CY+PH++PPY++L  DL +  + + L+  +D K N    L  +   N++CI IDLL+    CG++ +K+   KL Y+  LEV  +++ K PSKD+  P+SCI+   +  IK    +  S   I      + +  NLGLQVLD  N E+ S+ EGS IK DLSL+D++GK++ + VE+CY SN+ST+ + +  S+    +I KGCP    GF A F++ + PGIH+QSD F  F+     +I F  CFIKVC++  +C  + C    Q++    +DK      S  VI +R T + + K + + NTK     +   C + VCL+A QT
Sbjct:   19 NSHRYPKGSCIGKSENYCSEQVENSICNRLKNECFCKKGYVAIREE-DRVTCKTLLTNLKCRVDSDCMHINRSTCHPGAGQCACPGNTVYSIELHACRSR-FSEDQNPFCLTCQQLNGVCFKYDNGDNTSVSFKYKTEFIGCACSRNYATSITNYKKFSDLCRTTLSDIGEFCDNKQYFCQSKYAECRTINEENSSHRLCHCASDKVPVYQSHLHYFECFPKLSKTHPNCLSCHNLNGHCYDMNNDDIGDGCICPSRLSSETSNLDFQSNLQLCKTNTDNSQNDILVELTINICQSYSIHEQCSNGYLSICYQPHTEPPYEHLSHDLESNISTVNLVNRNDDKCN----LQKIASYNKYCIRIDLLDFSYNCGVQMHKLKFGKLLYQATLEVRLDRNIKQPSKDLVIPVSCISDHFQREIKNQSENLSSVIKI-----PEANILNLGLQVLDKFNKEVFSLVEGSEIKFDLSLVDSQGKFRGMRVEECYTSNHSTVIH-EKKSNYGDKIISKGCPIFSNGFFAPFKTFVSPGIHLQSDLFQVFRHGNLHSI-FYKCFIKVCVDVKDCENVKCYN--QELKYQSEDKQHLKNNSKSVIFKRWTHIEVQKLQGYKNTKPGTDNSV--CHHVVCLSASQT 638
[Close]
BLAST of Endoglin CD105 antigen vs. Planmine SMEST
Match: SMESG000035626.1 (SMESG000035626.1)

HSP 1 Score: 345.125 bits (884), Expect = 1.354e-105
Identity = 226/634 (35.65%), Postives = 338/634 (53.31%), Query Frame = 2 
Query:  191 HVVFAGSCVGKPSDFCSKQVDNSICNDEKNECFCKRGFVAIREEEDKVSCKTLLTDLKCRMDRDCNHVNSSTCHPGAGYCSCPGHTIYSSELHACRVKTFQIENNQFCLVCRNEGGVCFFYKDYDKKTAYIRADNSYVGCACPMKRFPISDIKHEICNNNLVDIGDYCDDNKDICRSKKAICAEKSLNNQIKICVCPKGYIKLYQSNLHYHECFPILNEN-SPLCSLCAASKGTCYDINDDDVGDGCICPSMYSTAETQIEFKHQNQF---CTISHLESNCKNNILKVCYKPHSQPPYDYLKDDLINKN--AIIRLIGGSDF------------KANSECFLN-----FVEDENQFCINIDLLEQIRECGIRSYKIAHRKLQYEFILEVLSNKSFKTPSKDMQFPLSCITKEPESAIKTYQTSTKSNQDIKNSIRKQKDKFNLGLQVLD-NNNNEIESVEEGSIIKLDLSLIDTKGKYKAISVEQCYFSNYSTIDYADSLSDKSVLLIKKGCPNVREGFMANFRSRIMP-----GIHIQSDGFHAFKLTTDSNILFIDCFIKVCINEANCWQIDCNKSPQQISQPKDDKSNYVIVRRRTQLNILKKRRFTNTKKQNKVTFGKCTYAVCLTALQT 2005
            H VF+G+C  +  ++C+ QV+NSICN  K+ECFC+ GFVAI+E   K+SCKTLLTDL CR+DRDC HV  S CHPGAG C CP   IY   ++ACR K F   N+ FC  CR  GG CF YK  D+K + ++  ++ +GCAC   R   SD    IC+ +LVDIG YC+D    CRSKKAIC+    ++ I  C C  GY+ +YQ  L Y ECFP+++E+ S  C+ C  S+G CYDIN+D  GD C+C + +S      E    N     CTISH+  +C N  + VCY PH++PPY  L   L N    A+++    ++              + SE F+N       E  N+FC NIDL +   E  I++ K+    ++Y   L ++ +     P KD  FPL+C+TK           + K N   ++   + +   +L L++++   N E  ++     +KLD+SL+D++G +  I + +C+ ++   I+  +  +    LL  K C N+   +    R R++      GIH Q+  F    L  +S+ILF  C I +C ++  C +      P +IS  +D    + +++R   LN  +   F      +     +C Y++CLT LQ 
Sbjct:   36 HFVFSGTCATRAPNYCNDQVENSICNTVKDECFCRNGFVAIKEGS-KISCKTLLTDLICRIDRDCMHVTGSMCHPGAGQCVCPAQHIYVEYINACRRK-FDDVNDPFCQNCRQNGGQCFKYKSQDRKNSPVKNKDA-IGCACNNHRM-TSDSTDTICDVHLVDIGGYCNDRDLKCRSKKAICSRIQNSDTISSCNCITGYVAVYQKTLRYFECFPVVSESASSRCAKCFQSEGYCYDINNDQEGDSCLCQNKFSN-----EMDGPNSLIKPCTISHVSVSCSNYHMNVCYIPHNRPPYRSLGVQLKNGRSLAVVKSPKATNKILPMPRRQKPPDVSYSEQFINNRLKISGELMNKFCANIDLTD---ERIIQADKLKKNNIRYSASLHIIVDSIKSNPGKDFVFPLTCVTKA---------INIKENSKNQSFASENEHSLSLDLRIINPETNAETNNINFNDQVKLDISLVDSQGTFSEIDILKCFVNDQKVIEEKNHSTSTGNLLYSK-CDNLSNYYS---RQRVVWLHTSHGIHYQTLEFRPQPL-NNSSILFFHCHILLCRHQILCSKHGFCGFPDEISAREDQ---FKVLQRSAYLNFHRSNNFDIPSISHGKEIKECRYSLCLTQLQA 640
The following BLAST results are available for this feature:
BLAST of Endoglin CD105 antigen vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Endoglin CD105 antigen vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Endoglin CD105 antigen vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Endoglin CD105 antigen vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Endoglin CD105 antigen vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Endoglin CD105 antigen vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Endoglin CD105 antigen vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Endoglin CD105 antigen vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
A0A5K4F0526.541e-11638.66Uncharacterized protein OS=Schistosoma mansoni OX=... [more]
A0A4E0RJA63.076e-11534.11ZP domain-containing protein OS=Fasciola hepatica ... [more]
A0A5K4F1C88.885e-11538.56Uncharacterized protein OS=Schistosoma mansoni OX=... [more]
A0A183MJ204.893e-11037.58Uncharacterized protein OS=Schistosoma margrebowie... [more]
A0A4Z2CXR85.698e-10938.11Endoglin antigen OS=Schistosoma japonicum OX=6182 ... [more]
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BLAST of Endoglin CD105 antigen vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Endoglin CD105 antigen vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Endoglin CD105 antigen vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Endoglin CD105 antigen vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Endoglin CD105 antigen vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Endoglin CD105 antigen vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5
Match NameE-valueIdentityDescription
SMESG000039228.10.000e+099.87SMESG000039228.1[more]
SMESG000039228.10.000e+099.55SMESG000039228.1[more]
SMESG000020512.14.711e-15641.98SMESG000020512.1[more]
SMESG000020512.14.043e-15140.66SMESG000020512.1[more]
SMESG000035626.11.354e-10535.65SMESG000035626.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30013709 ID=SMED30013709|Name=Endoglin CD105 antigen|organism=Schmidtea mediterranea sexual|type=transcript|length=2477bp
GTTATCTATATACATTGAATGGGAAAGGTAAACAGTTAGAATTGAAAATA
AATAAAAAAGAAACATTCCTTCAATGTTCTATTGTGGATTTTCTATTTTA
TAAATGGACTTGTATTTAATATTCACCTGTGTTTTGTTGATTGTCCATCT
GATTATCATTGTCAATCAAATCGTTTTATCCACAGATGAACATGTTGTTT
TTGCAGGATCTTGTGTAGGGAAACCATCAGACTTCTGTTCAAAGCAAGTT
GACAATTCTATATGTAACGACGAAAAAAATGAATGCTTTTGCAAACGTGG
ATTTGTAGCAATTCGAGAAGAAGAAGATAAAGTTTCTTGCAAAACACTTC
TGACGGATTTAAAATGTCGAATGGATCGAGATTGTAATCATGTGAACAGC
AGCACTTGTCATCCCGGAGCAGGCTACTGCTCATGTCCTGGTCATACAAT
TTACTCCTCAGAATTACACGCCTGCAGAGTAAAGACTTTTCAAATTGAAA
ACAACCAATTTTGTCTCGTTTGTCGCAATGAAGGAGGCGTTTGTTTTTTC
TACAAAGATTATGATAAAAAAACAGCATACATTCGTGCTGATAACAGTTA
CGTAGGATGCGCATGTCCTATGAAACGATTTCCAATATCAGATATCAAAC
ACGAAATTTGCAACAATAATTTAGTGGATATCGGAGATTATTGTGACGAT
AACAAAGATATTTGCCGCTCAAAAAAAGCAATTTGTGCCGAAAAGTCTTT
GAACAATCAGATCAAAATTTGTGTTTGTCCAAAGGGTTACATTAAGTTAT
ATCAATCAAATCTTCACTACCATGAGTGCTTTCCTATTTTGAATGAAAAT
TCACCGTTATGCTCATTATGTGCCGCCTCTAAGGGTACATGCTATGATAT
CAATGATGATGATGTCGGAGATGGATGTATATGTCCTTCTATGTATTCAA
CAGCCGAAACTCAGATTGAATTTAAACATCAGAATCAATTTTGCACAATA
TCGCATTTAGAATCAAACTGCAAAAACAATATTTTAAAAGTTTGCTATAA
ACCTCATTCACAGCCTCCGTATGACTATCTAAAAGATGATTTAATTAACA
AAAATGCCATAATTCGTTTGATCGGTGGCAGCGATTTCAAAGCCAATTCC
GAATGTTTTCTCAATTTTGTAGAAGATGAAAATCAGTTCTGTATAAATAT
AGATTTATTAGAACAAATTAGAGAATGCGGCATTCGGTCGTATAAAATTG
CACATAGAAAACTCCAATATGAATTTATTCTGGAAGTCCTCAGTAATAAA
TCATTCAAAACTCCATCAAAGGACATGCAGTTCCCATTATCGTGCATTAC
AAAAGAACCAGAAAGTGCCATTAAAACATATCAAACGTCTACTAAATCAA
ATCAAGATATCAAAAACTCGATAAGAAAACAAAAAGATAAATTCAATCTT
GGTCTTCAGGTGTTGGATAATAATAACAACGAAATAGAATCTGTTGAAGA
AGGTTCAATAATAAAGCTAGATTTGTCTTTGATTGATACAAAAGGAAAAT
ACAAAGCAATAAGTGTAGAACAATGCTATTTTAGCAACTACTCAACCATA
GACTATGCGGATTCTTTATCGGATAAATCTGTTCTCTTAATAAAAAAAGG
CTGCCCAAACGTACGGGAAGGTTTTATGGCCAATTTTCGGTCGAGAATAA
TGCCCGGCATTCACATCCAGAGTGACGGGTTTCACGCTTTTAAACTCACT
ACGGACTCAAATATTTTATTCATTGATTGTTTTATTAAAGTCTGTATAAA
TGAAGCAAATTGTTGGCAGATTGACTGCAATAAAAGTCCCCAGCAAATTT
CACAGCCAAAGGATGACAAATCAAATTATGTAATTGTGCGTAGAAGGACC
CAATTAAATATTCTCAAAAAGCGGCGATTTACAAACACAAAAAAACAAAA
CAAAGTAACTTTTGGAAAATGTACTTATGCAGTTTGTCTGACTGCGTTAC
AAACTTCTGTCATGGCGGCTCTTCTTGTTACTCTAATCATACTAATTATC
TTCATAATTTTGGTAATTTATCGCAAAAACCGACTTTATCAAGAACAAAA
CAAAATGGCTCATCACTGTCTCAATGAACACAATCAGTCATTTTATTCTA
GACATCAACATTCTGAGACCAAAACTCATCCAGTTAGACATAGATGTATT
TCATTAGCCATGAGATCTATTGATGACATAAATGAAAACAGTTTGAGAAC
TATTCCTCAATCAGACTTTCTGCCAACCCCTATTCATAGGTTTCAACTTG
TCAATGATTATGAAATGGAAAACTCATCAGCAATCAATCAAAATAATCCT
TCTTTTATACCTTTGACTTCAACTGTTCAAAGAACACCAAATGTAAAAGT
TGCCCATCAGAGCCAATCACAAGCAGAAACCGTCACAAGAGTGTAGATTT
CCATTTAAGACCAGTATTGAATGAAAG
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protein sequence of SMED30013709-orf-1

>SMED30013709-orf-1 ID=SMED30013709-orf-1|Name=SMED30013709-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=781bp
MDLYLIFTCVLLIVHLIIIVNQIVLSTDEHVVFAGSCVGKPSDFCSKQVD
NSICNDEKNECFCKRGFVAIREEEDKVSCKTLLTDLKCRMDRDCNHVNSS
TCHPGAGYCSCPGHTIYSSELHACRVKTFQIENNQFCLVCRNEGGVCFFY
KDYDKKTAYIRADNSYVGCACPMKRFPISDIKHEICNNNLVDIGDYCDDN
KDICRSKKAICAEKSLNNQIKICVCPKGYIKLYQSNLHYHECFPILNENS
PLCSLCAASKGTCYDINDDDVGDGCICPSMYSTAETQIEFKHQNQFCTIS
HLESNCKNNILKVCYKPHSQPPYDYLKDDLINKNAIIRLIGGSDFKANSE
CFLNFVEDENQFCINIDLLEQIRECGIRSYKIAHRKLQYEFILEVLSNKS
FKTPSKDMQFPLSCITKEPESAIKTYQTSTKSNQDIKNSIRKQKDKFNLG
LQVLDNNNNEIESVEEGSIIKLDLSLIDTKGKYKAISVEQCYFSNYSTID
YADSLSDKSVLLIKKGCPNVREGFMANFRSRIMPGIHIQSDGFHAFKLTT
DSNILFIDCFIKVCINEANCWQIDCNKSPQQISQPKDDKSNYVIVRRRTQ
LNILKKRRFTNTKKQNKVTFGKCTYAVCLTALQTSVMAALLVTLIILIIF
IILVIYRKNRLYQEQNKMAHHCLNEHNQSFYSRHQHSETKTHPVRHRCIS
LAMRSIDDINENSLRTIPQSDFLPTPIHRFQLVNDYEMENSSAINQNNPS
FIPLTSTVQRTPNVKVAHQSQSQAETVTRV*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000099neuron
PLANA:0000418head
PLANA:0003116parenchymal cell
Vocabulary: INTERPRO
TermDefinition
IPR001507ZP_dom
Vocabulary: cellular component
TermDefinition
GO:0016020membrane
GO:0016021integral component of membrane
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR001507Zona pellucida domainPROSITEPS51034ZP_2coord: 305..582
score: 17.032
NoneNo IPR availableSIGNALP_EUKSignalP-noTMSignalP-noTMcoord: 1..26
score: 0.767
NoneNo IPR availableTMHMMTMhelixcoord: 634..656
NoneNo IPR availableTMHMMTMhelixcoord: 3..25