MAP3K-1
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Overview
Neoblast Clusters
Zeng et. al., 2018▻ Overview▻ Neoblast Population▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Overview
Single cell RNA-seq of pluripotent neoblasts and its early progeniesWe isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)Explore this single cell expression dataset with our NB Cluster Shiny App
Neoblast Population
Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Embryonic Expression
Davies et. al., 2017
Hover the mouse over a column in the graph to view average RPKM values per sample. Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult. back to top Anatomical Expression
PAGE et. al., 2020SMED30013686 has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGEPAGE Curations: 7
Homology
BLAST of MAP3K-1 vs. Ensembl Human
Match: MAP3K1 (mitogen-activated protein kinase kinase kinase 1 [Source:HGNC Symbol;Acc:HGNC:6848]) HSP 1 Score: 308.916 bits (790), Expect = 2.176e-85 Identity = 143/285 (50.18%), Postives = 197/285 (69.12%), Query Frame = 3
Query: 2859 PGLGVFSSEYRSGYEWCQGPLLGTGAFSKCYQGRDVRTGLLMAVKQISISHSSIDKNEEIIKAVKTEVNLMIQLNHPNVLPLLGAMFSPTDNIISMFVRWMPGGSVASLLNQYSAFLEPVTLAYALQTARGLSYIHSNRILHRDLKGANLLLDSSGMRLRISDFGASARLSNGRDSNASDFKGQLLGTVAFMAPEVLRGEEYGRSCDVWSFACCIIEMLTGSQPWRDRNHTNHLALMYTIASAEEPPKLPEQISADLTELLTDCLNRDPKKRPLSSKLESYRVFK 3713
PG YR EW +G +G GAFS CYQ +DV TG LMAVKQ++ ++ + EE+++A++ E+ +M LNHPN++ +LGA ++ ++F+ WM GGSVA LL++Y AF E V + Y Q RGLSY+H N+I+HRD+KGANLL+DS+G RLRI+DFGA+ARL++ + + A +F+GQLLGT+AFMAPEVLRG++YGRSCDVWS C IIEM PW H+NHLAL++ IASA P +P +S L ++ CL P+ RP S +L + VF+
Sbjct: 1228 PGHTKAKQPYREDTEWLKGQQIGLGAFSSCYQAQDVGTGTLMAVKQVTYVRNTSSEQEEVVEALREEIRMMSHLNHPNIIRMLGATCEKSN--YNLFIEWMAGGSVAHLLSKYGAFKESVVINYTEQLLRGLSYLHENQIIHRDVKGANLLIDSTGQRLRIADFGAAARLAS-KGTGAGEFQGQLLGTIAFMAPEVLRGQQYGRSCDVWSVGCAIIEMACAKPPWNAEKHSNHLALIFKIASATTAPSIPSHLSPGLRDVALRCLELQPQDRPPSRELLKHPVFR 1509 HSP 2 Score: 70.8626 bits (172), Expect = 1.881e-11 Identity = 43/142 (30.28%), Postives = 76/142 (53.52%), Query Frame = 3
Query: 1536 TGLMLKEAFRVIARLLDDTSYTLFVGALRAFREILGYLICRTESEVERMSRMISPVLCQLLRICGDNSQKKKAQMCLSALFELANGQEGGMALGREI-KKSSLPVTGWQRLAKFAIANHHRFKAVH-CYGRLSLLERLLDKF 1955
+G +++ V++ + D Y ++V AL+ R +L Y C + +E ++ R++ PV+ +L C D + + +Q+ +S L EL GQ G +A+GREI K S+ + G + + N GRL L++RLL +F
Sbjct: 628 SGDVVEACCSVLSMVCADPVYKVYVAALKTLRAMLVYTPCHSLAERIKLQRLLQPVVDTILVKCAD-ANSRTSQLSISTLLELCKGQAGELAVGREILKAGSIGIGGVDYVLNCILGNQTESNNWQELLGRLCLIDRLLLEF 768 HSP 3 Score: 65.855 bits (159), Expect = 6.211e-10 Identity = 30/72 (41.67%), Postives = 42/72 (58.33%), Query Frame = 3
Query: 927 DEITCSICLQEMNIAQLLIFCHN-CSNEFHKKCILIWLKECKKNNEELTCPLCRKSWPSDDI-SRDIVSPLE 1136
+E C ICL M + L C + C N+ H C+ IW +EC++N E L CPLCR W S D S ++ SP++
Sbjct: 439 EEQMCPICLLGMLDEESLTVCEDGCRNKLHHHCMSIWAEECRRNREPLICPLCRSKWRSHDFYSHELSSPVD 510
BLAST of MAP3K-1 vs. Ensembl Human
Match: MAP3K2 (mitogen-activated protein kinase kinase kinase 2 [Source:HGNC Symbol;Acc:HGNC:6854]) HSP 1 Score: 186.422 bits (472), Expect = 8.215e-49 Identity = 108/286 (37.76%), Postives = 156/286 (54.55%), Query Frame = 3
Query: 2889 RSGYEWCQGPLLGTGAFSKCYQGRDVRTGLLMAVKQISISHSSIDKNEEIIKAVKTEVNLMIQLNHPNVLPLLGAMFSPTDNIISMFVRWMPGGSVASLLNQYSAFLEPVTLAYALQTARGLSYIHSNRILHRDLKGANLLLDSSGMRLRISDFGASARLSNGRDSNASDFKGQLLGTVAFMAPEVLRGEEYGRSCDVWSFACCIIEMLTGSQPWRDRNHTNHLALMYTIASAEEPPKLPEQISADLTELLTDCLNRDPKKRPLSSKLESYRVFKHLTS*MFFRYH 3746
R+ W G LLG GAF + Y DV TG +AVKQ+ S + ++E+ A++ E+ L+ L H ++ G + P + +S+F+ +MPGGS+ L Y A E VT Y Q G+ Y+HSN I+HRD+KGAN+L DS+G +++ DFGAS RL S + GT +M+PEV+ GE YGR D+WS AC ++EMLT PW + +A ++ IA+ PKLP +S D T + + K RP + +L +H MF YH
Sbjct: 351 RAPTNWRLGKLLGQGAFGRVYLCYDVDTGRELAVKQVQFDPDSPETSKEV-NALECEIQLLKNLLHERIVQYYGCLRDPQEKTLSIFMEYMPGGSIKDQLKAYGALTENVTRKYTRQILEGVHYLHSNMIVHRDIKGANILRDSTG-NVKLGDFGASKRLQTICLSGTG--MKSVTGTPYWMSPEVISGEGYGRKADIWSVACTVVEMLTEKPPWAE---FEAMAAIFKIATQPTNPKLPPHVS-DYTRDFLKRIFVEAKLRPSADEL-----LRH----MFVHYH 619
BLAST of MAP3K-1 vs. Ensembl Human
Match: MAP3K2 (mitogen-activated protein kinase kinase kinase 2 [Source:HGNC Symbol;Acc:HGNC:6854]) HSP 1 Score: 186.422 bits (472), Expect = 8.215e-49 Identity = 108/286 (37.76%), Postives = 156/286 (54.55%), Query Frame = 3
Query: 2889 RSGYEWCQGPLLGTGAFSKCYQGRDVRTGLLMAVKQISISHSSIDKNEEIIKAVKTEVNLMIQLNHPNVLPLLGAMFSPTDNIISMFVRWMPGGSVASLLNQYSAFLEPVTLAYALQTARGLSYIHSNRILHRDLKGANLLLDSSGMRLRISDFGASARLSNGRDSNASDFKGQLLGTVAFMAPEVLRGEEYGRSCDVWSFACCIIEMLTGSQPWRDRNHTNHLALMYTIASAEEPPKLPEQISADLTELLTDCLNRDPKKRPLSSKLESYRVFKHLTS*MFFRYH 3746
R+ W G LLG GAF + Y DV TG +AVKQ+ S + ++E+ A++ E+ L+ L H ++ G + P + +S+F+ +MPGGS+ L Y A E VT Y Q G+ Y+HSN I+HRD+KGAN+L DS+G +++ DFGAS RL S + GT +M+PEV+ GE YGR D+WS AC ++EMLT PW + +A ++ IA+ PKLP +S D T + + K RP + +L +H MF YH
Sbjct: 351 RAPTNWRLGKLLGQGAFGRVYLCYDVDTGRELAVKQVQFDPDSPETSKEV-NALECEIQLLKNLLHERIVQYYGCLRDPQEKTLSIFMEYMPGGSIKDQLKAYGALTENVTRKYTRQILEGVHYLHSNMIVHRDIKGANILRDSTG-NVKLGDFGASKRLQTICLSGTG--MKSVTGTPYWMSPEVISGEGYGRKADIWSVACTVVEMLTEKPPWAE---FEAMAAIFKIATQPTNPKLPPHVS-DYTRDFLKRIFVEAKLRPSADEL-----LRH----MFVHYH 619
BLAST of MAP3K-1 vs. Ensembl Human
Match: MAP3K3 (mitogen-activated protein kinase kinase kinase 3 [Source:HGNC Symbol;Acc:HGNC:6855]) HSP 1 Score: 181.03 bits (458), Expect = 5.267e-47 Identity = 102/266 (38.35%), Postives = 149/266 (56.02%), Query Frame = 3
Query: 2904 WCQGPLLGTGAFSKCYQGRDVRTGLLMAVKQISISHSSIDKNEEIIKAVKTEVNLMIQLNHPNVLPLLGAMFSPTDNIISMFVRWMPGGSVASLLNQYSAFLEPVTLAYALQTARGLSYIHSNRILHRDLKGANLLLDSSGMRLRISDFGASARLSNGRDSNASDFKGQLLGTVAFMAPEVLRGEEYGRSCDVWSFACCIIEMLTGSQPWRDRNHTNHLALMYTIASAEEPPKLPEQISADLTELLTDCLNR---DPKKRPLSSKL 3692
W +G LLG GAF + Y DV TG +A KQ+ S + ++E+ A++ E+ L+ L H ++ G + + +++F+ +MPGGSV L Y A E VT Y Q G+SY+HSN I+HRD+KGAN+L DS+G +++ DFGAS RL S + GT +M+PEV+ GE YGR DVWS C ++EMLT PW + +A ++ IA+ P+LP IS E D L R + ++RP + +L
Sbjct: 358 WRRGKLLGQGAFGRVYLCYDVDTGRELASKQVQFDPDSPETSKEV-SALECEIQLLKNLQHERIVQYYGCLRDRAEKTLTIFMEYMPGGSVKDQLKAYGALTESVTRKYTRQILEGMSYLHSNMIVHRDIKGANILRDSAG-NVKLGDFGASKRLQTICMSGTG--MRSVTGTPYWMSPEVISGEGYGRKADVWSLGCTVVEMLTEKPPWAE---YEAMAAIFKIATQPTNPQLPSHIS----EHGRDFLRRIFVEARQRPSAEEL 612
BLAST of MAP3K-1 vs. Ensembl Human
Match: MAP3K3 (mitogen-activated protein kinase kinase kinase 3 [Source:HGNC Symbol;Acc:HGNC:6855]) HSP 1 Score: 181.415 bits (459), Expect = 5.486e-47 Identity = 102/266 (38.35%), Postives = 149/266 (56.02%), Query Frame = 3
Query: 2904 WCQGPLLGTGAFSKCYQGRDVRTGLLMAVKQISISHSSIDKNEEIIKAVKTEVNLMIQLNHPNVLPLLGAMFSPTDNIISMFVRWMPGGSVASLLNQYSAFLEPVTLAYALQTARGLSYIHSNRILHRDLKGANLLLDSSGMRLRISDFGASARLSNGRDSNASDFKGQLLGTVAFMAPEVLRGEEYGRSCDVWSFACCIIEMLTGSQPWRDRNHTNHLALMYTIASAEEPPKLPEQISADLTELLTDCLNR---DPKKRPLSSKL 3692
W +G LLG GAF + Y DV TG +A KQ+ S + ++E+ A++ E+ L+ L H ++ G + + +++F+ +MPGGSV L Y A E VT Y Q G+SY+HSN I+HRD+KGAN+L DS+G +++ DFGAS RL S + GT +M+PEV+ GE YGR DVWS C ++EMLT PW + +A ++ IA+ P+LP IS E D L R + ++RP + +L
Sbjct: 362 WRRGKLLGQGAFGRVYLCYDVDTGRELASKQVQFDPDSPETSKEV-SALECEIQLLKNLQHERIVQYYGCLRDRAEKTLTIFMEYMPGGSVKDQLKAYGALTESVTRKYTRQILEGMSYLHSNMIVHRDIKGANILRDSAG-NVKLGDFGASKRLQTICMSGTG--MRSVTGTPYWMSPEVISGEGYGRKADVWSLGCTVVEMLTEKPPWAE---YEAMAAIFKIATQPTNPQLPSHIS----EHGRDFLRRIFVEARQRPSAEEL 616
BLAST of MAP3K-1 vs. Ensembl Celegans
Match: gck-1 (Germinal center kinase 1 [Source:UniProtKB/Swiss-Prot;Acc:H2L099]) HSP 1 Score: 127.487 bits (319), Expect = 7.628e-30 Identity = 81/265 (30.57%), Postives = 135/265 (50.94%), Query Frame = 3
Query: 2922 LGTGAFSKCYQGRDVRTGLLMAVKQISISHSSIDKNEEIIKAVKTEVNLMIQLNHPNVLPLLGAMFSPTDNIISMFVRWMPGGSVASLLNQYSAFLEPVTLAYAL-QTARGLSYIHSNRILHRDLKGANLLLDSSGMRLRISDFGASARLSNGRDSNASDFKGQLLGTVAFMAPEVLRGEEYGRSCDVWSFACCIIEMLTGSQPWRDRNHTNHLALMYTIASAEEPPKLPEQISADLTELLTDCLNRDPKKRPLSSKLESYRVFK 3713
+G G+F + Y+G D RTG ++A+K I + ++ E+ I+ ++ E+ ++ Q + V G+ + + + + ++ GGS L S L+ +A L + +GL Y+HS R +HRD+KGAN+LLD ++I D+G + L +N +GT FMAPEV++G EY D+WS IE+ G P D + + +++ I P Q S E + CLN+DP+ RP +S L ++ K
Sbjct: 25 IGRGSFGEVYKGIDNRTGRVVAIKIIDL-----EQAEDEIEDIQQEIQVLSQCDSQYVTKYFGSFLKGSK--LWIIMEYLGGGSALDLTK--SGKLDESHIAVILREILKGLEYLHSERKIHRDIKGANVLLDRQTAAVKICDYGVAKPLDTVLKANT------FVGTPFFMAPEVVKG-EYSIEADIWSLGITAIELANGEPPHSD---LHPMRVLFLIPKNPPPVLQGSQWSKPFKEFVEMCLNKDPENRPSASTLLKHQFIK 270
BLAST of MAP3K-1 vs. Ensembl Celegans
Match: gck-1 (Germinal center kinase 1 [Source:UniProtKB/Swiss-Prot;Acc:H2L099]) HSP 1 Score: 127.487 bits (319), Expect = 7.642e-30 Identity = 81/265 (30.57%), Postives = 135/265 (50.94%), Query Frame = 3
Query: 2922 LGTGAFSKCYQGRDVRTGLLMAVKQISISHSSIDKNEEIIKAVKTEVNLMIQLNHPNVLPLLGAMFSPTDNIISMFVRWMPGGSVASLLNQYSAFLEPVTLAYAL-QTARGLSYIHSNRILHRDLKGANLLLDSSGMRLRISDFGASARLSNGRDSNASDFKGQLLGTVAFMAPEVLRGEEYGRSCDVWSFACCIIEMLTGSQPWRDRNHTNHLALMYTIASAEEPPKLPEQISADLTELLTDCLNRDPKKRPLSSKLESYRVFK 3713
+G G+F + Y+G D RTG ++A+K I + ++ E+ I+ ++ E+ ++ Q + V G+ + + + + ++ GGS L S L+ +A L + +GL Y+HS R +HRD+KGAN+LLD ++I D+G + L +N +GT FMAPEV++G EY D+WS IE+ G P D + + +++ I P Q S E + CLN+DP+ RP +S L ++ K
Sbjct: 20 IGRGSFGEVYKGIDNRTGRVVAIKIIDL-----EQAEDEIEDIQQEIQVLSQCDSQYVTKYFGSFLKGSK--LWIIMEYLGGGSALDLTK--SGKLDESHIAVILREILKGLEYLHSERKIHRDIKGANVLLDRQTAAVKICDYGVAKPLDTVLKANT------FVGTPFFMAPEVVKG-EYSIEADIWSLGITAIELANGEPPHSD---LHPMRVLFLIPKNPPPVLQGSQWSKPFKEFVEMCLNKDPENRPSASTLLKHQFIK 265
BLAST of MAP3K-1 vs. Ensembl Celegans
Match: gck-1 (Germinal center kinase 1 [Source:UniProtKB/Swiss-Prot;Acc:H2L099]) HSP 1 Score: 127.487 bits (319), Expect = 9.253e-30 Identity = 81/265 (30.57%), Postives = 135/265 (50.94%), Query Frame = 3
Query: 2922 LGTGAFSKCYQGRDVRTGLLMAVKQISISHSSIDKNEEIIKAVKTEVNLMIQLNHPNVLPLLGAMFSPTDNIISMFVRWMPGGSVASLLNQYSAFLEPVTLAYAL-QTARGLSYIHSNRILHRDLKGANLLLDSSGMRLRISDFGASARLSNGRDSNASDFKGQLLGTVAFMAPEVLRGEEYGRSCDVWSFACCIIEMLTGSQPWRDRNHTNHLALMYTIASAEEPPKLPEQISADLTELLTDCLNRDPKKRPLSSKLESYRVFK 3713
+G G+F + Y+G D RTG ++A+K I + ++ E+ I+ ++ E+ ++ Q + V G+ + + + + ++ GGS L S L+ +A L + +GL Y+HS R +HRD+KGAN+LLD ++I D+G + L +N +GT FMAPEV++G EY D+WS IE+ G P D + + +++ I P Q S E + CLN+DP+ RP +S L ++ K
Sbjct: 40 IGRGSFGEVYKGIDNRTGRVVAIKIIDL-----EQAEDEIEDIQQEIQVLSQCDSQYVTKYFGSFLKGSK--LWIIMEYLGGGSALDLTK--SGKLDESHIAVILREILKGLEYLHSERKIHRDIKGANVLLDRQTAAVKICDYGVAKPLDTVLKANT------FVGTPFFMAPEVVKG-EYSIEADIWSLGITAIELANGEPPHSD---LHPMRVLFLIPKNPPPVLQGSQWSKPFKEFVEMCLNKDPENRPSASTLLKHQFIK 285
BLAST of MAP3K-1 vs. Ensembl Celegans
Match: gck-1 (Germinal center kinase 1 [Source:UniProtKB/Swiss-Prot;Acc:H2L099]) HSP 1 Score: 128.257 bits (321), Expect = 9.258e-30 Identity = 81/265 (30.57%), Postives = 134/265 (50.57%), Query Frame = 3
Query: 2922 LGTGAFSKCYQGRDVRTGLLMAVKQISISHSSIDKNEEIIKAVKTEVNLMIQLNHPNVLPLLGAMFSPTDNIISMFVRWMPGGSVASLLNQYSAFLEPVTLAYAL-QTARGLSYIHSNRILHRDLKGANLLLDSSGMRLRISDFGASARLSNGRDSNASDFKGQLLGTVAFMAPEVLRGEEYGRSCDVWSFACCIIEMLTGSQPWRDRNHTNHLALMYTIASAEEPPKLPEQISADLTELLTDCLNRDPKKRPLSSKLESYRVFK 3713
+G G+F + Y+G D RTG ++A+K I + + E+ I+ ++ E+ ++ Q + V G+ + + + + ++ GGS L S L+ +A L + +GL Y+HS R +HRD+KGAN+LLD ++I D+G + L +N +GT FMAPEV++G EY D+WS IE+ G P D + + +++ I P Q S E + CLN+DP+ RP +S L ++ K
Sbjct: 190 IGRGSFGEVYKGIDNRTGRVVAIKIIDLEQA-----EDEIEDIQQEIQVLSQCDSQYVTKYFGSFLKGSK--LWIIMEYLGGGSALDLTK--SGKLDESHIAVILREILKGLEYLHSERKIHRDIKGANVLLDRQTAAVKICDYGVAKPLDTVLKANT------FVGTPFFMAPEVVKG-EYSIEADIWSLGITAIELANGEPPHSD---LHPMRVLFLIPKNPPPVLQGSQWSKPFKEFVEMCLNKDPENRPSASTLLKHQFIK 435
BLAST of MAP3K-1 vs. Ensembl Celegans
Match: nsy-1 (Mitogen-activated protein kinase kinase kinase nsy-1 [Source:UniProtKB/Swiss-Prot;Acc:Q21029]) HSP 1 Score: 128.642 bits (322), Expect = 1.678e-29 Identity = 83/266 (31.20%), Postives = 134/266 (50.38%), Query Frame = 3
Query: 2919 LLGTGAFSKCYQGRDVRTGLLMAVKQISISHSSIDKNEEIIKAVKTEVNLMIQLNHPNVLPLLGAMFSPTD---NIISMFVRWMPGGSVASLL-NQYSAFLEPVTLAYALQTARGLSYIHSNRILHRDLKGANLLLDSSGMRLRISDFGASARLSNGRDSNASDFKGQLLGTVAFMAPEVL----RGEEYGRSCDVWSFACCIIEMLTGSQPWRDRNHTNHLALMYTIASAEEPPKLPEQISADLTELLTDCLNRDPKKRPLSSKL 3692
+LG G + Y RD+ T + VK+I + K +E ++ + E++L L H N++ LG D + +F+ +PGGS++SLL +++ E Y Q GL Y+H +I+HRD+KG N+L+++ +ISDFG RL+ G + F GT+ +MAPEV+ RG YG D+WSF C ++EM TG P+ + N A M+ + + P +P +I+ + C + RP + L
Sbjct: 669 VLGKGTYGTVYAARDMDTQRQIVVKEIEV------KYDEEVQPLMEEISLHSTLCHANIVQYLGCDLVGKDGSNDHFLIFMEHVPGGSLSSLLRSKWGPMNENAMNYYGKQILEGLKYLHELKIVHRDIKGDNVLVNTYSGVCKISDFGTCKRLA-GLNPVTETFT----GTLQYMAPEVIDHGQRG--YGAPADIWSFGCTMVEMATGRPPFVEMQ--NPQAAMFRVGMFKTHPPIPTEITEKCRNFIKSCFLPEACDRPSAKDL 919
BLAST of MAP3K-1 vs. Ensembl Fly
Match: Ask1 (gene:FBgn0014006 transcript:FBtr0083819) HSP 1 Score: 140.198 bits (352), Expect = 4.231e-33 Identity = 87/278 (31.29%), Postives = 143/278 (51.44%), Query Frame = 3
Query: 2883 EYRSGY-EWCQGPLLGTGAFSKCYQGRDVRTGLLMAVKQISISHSSIDKNEEIIKAVKTEVNLMIQLNHPNVLPLLGAMFSPTDNIISMFVRWMPGGSVASLLNQYSAFL---EPVTLAYALQTARGLSYIHSNRILHRDLKGANLLLDSSGMRLRISDFGASARLSNGRDSNASDFKGQLLGTVAFMAPEVL----RGEEYGRSCDVWSFACCIIEMLTGSQPWRDRNHTNHLALMYTIASAEEPPKLPEQISADLTELLTDCLNRDPKKRPLSSKL 3692
EY Y E + +LG G + Y RD +T + +A+K++ +KN + ++ + E+ L QL H N++ LG+ + +F+ +PGGS++ LL L E Y+ Q GL Y+H I+HRD+KG N+L+++ ++ISDFG S RL + + GT+ +MAPEV+ RG YG + D+WSF C +EM TG P+ + + A M+ + ++ P +PE++SA+ + C RP +S+L
Sbjct: 410 EYEYDYDEQNRKMVLGKGTYGTVYAARDKQTQVRIAIKEVP------EKNSQDVQPLHEEIKLHSQLRHRNIVRYLGS--CSENGFFKIFMEQVPGGSLSDLLETKWGPLKDNESTMAFYSKQILEGLKYLHEQDIVHRDIKGDNVLVNTYSGVVKISDFGTSKRL-----ARINPMTETFTGTLQYMAPEVIDQGVRG--YGPAADIWSFGCTNVEMATGKPPFIELGSAH--AAMFKVGFYKKHPNIPEELSANAKNFILRCFAISVMDRPSASQL 670
BLAST of MAP3K-1 vs. Ensembl Fly
Match: Ask1 (gene:FBgn0014006 transcript:FBtr0300256) HSP 1 Score: 140.198 bits (352), Expect = 4.712e-33 Identity = 87/278 (31.29%), Postives = 143/278 (51.44%), Query Frame = 3
Query: 2883 EYRSGY-EWCQGPLLGTGAFSKCYQGRDVRTGLLMAVKQISISHSSIDKNEEIIKAVKTEVNLMIQLNHPNVLPLLGAMFSPTDNIISMFVRWMPGGSVASLLNQYSAFL---EPVTLAYALQTARGLSYIHSNRILHRDLKGANLLLDSSGMRLRISDFGASARLSNGRDSNASDFKGQLLGTVAFMAPEVL----RGEEYGRSCDVWSFACCIIEMLTGSQPWRDRNHTNHLALMYTIASAEEPPKLPEQISADLTELLTDCLNRDPKKRPLSSKL 3692
EY Y E + +LG G + Y RD +T + +A+K++ +KN + ++ + E+ L QL H N++ LG+ + +F+ +PGGS++ LL L E Y+ Q GL Y+H I+HRD+KG N+L+++ ++ISDFG S RL + + GT+ +MAPEV+ RG YG + D+WSF C +EM TG P+ + + A M+ + ++ P +PE++SA+ + C RP +S+L
Sbjct: 577 EYEYDYDEQNRKMVLGKGTYGTVYAARDKQTQVRIAIKEVP------EKNSQDVQPLHEEIKLHSQLRHRNIVRYLGS--CSENGFFKIFMEQVPGGSLSDLLETKWGPLKDNESTMAFYSKQILEGLKYLHEQDIVHRDIKGDNVLVNTYSGVVKISDFGTSKRL-----ARINPMTETFTGTLQYMAPEVIDQGVRG--YGPAADIWSFGCTNVEMATGKPPFIELGSAH--AAMFKVGFYKKHPNIPEELSANAKNFILRCFAISVMDRPSASQL 837
BLAST of MAP3K-1 vs. Ensembl Fly
Match: Mekk1 (gene:FBgn0024329 transcript:FBtr0083684) HSP 1 Score: 134.42 bits (337), Expect = 3.101e-31 Identity = 78/276 (28.26%), Postives = 142/276 (51.45%), Query Frame = 3
Query: 2898 YEWCQGPLLGTGAFSKCYQGRDVRTGLLMAVKQISISHSSIDKNEEIIKAVKTEVNLMIQLNHPNVLPLLGAMFSPTDNIISMFVRWMPGGSVASLLNQYSAFLEPVTLAYALQTARGLSYIHSNRILHRDLKGANLLLDSSGMRLRISDFGASARLSNGRDSNASDFKGQLLGTVAFMAPEVL---RGEEYGRSCDVWSFACCIIEMLTGSQPWRDRNHTNHLALMYTIASAEEPPKLPEQISADLTELLTDCLNRDPKKRPLSSKLESYRVFKH 3716
+ W +G +G G F K Y + TG LMA+K+I+I +K V E+ ++ + H N++ G + +I F+ G++ SL+ E +T + Q G+S +H + I+HRD+K AN+ L L++ DFG++ ++ + + +G +GT A+MAPEV + +GR+ D+WS C ++EM +G +PW + ++ +M+ + E+ P+ PE +S + + + CL DPK+R + +L + K+
Sbjct: 1280 FRWHRGIKIGQGRFGKVYTAVNNNTGELMAMKEIAIQPGET----RALKNVAEELKILEGIKHKNLVRYYGIEVHREELLI--FMELCSEGTLESLVELTGNLPEALTRRFTAQLLSGVSELHKHGIVHRDIKTANIFLVDGSNSLKLGDFGSAVKI-QAHTTVPGELQG-YVGTQAYMAPEVFTKTNSDGHGRAADIWSVGCVVVEMASGKRPWAQFD--SNFQIMFKVGMGEK-PQAPESLSQEGHDFIDHCLQHDPKRRLTAVELLEHNFCKY 1544
BLAST of MAP3K-1 vs. Ensembl Fly
Match: Mekk1 (gene:FBgn0024329 transcript:FBtr0331353) HSP 1 Score: 134.42 bits (337), Expect = 3.594e-31 Identity = 78/276 (28.26%), Postives = 142/276 (51.45%), Query Frame = 3
Query: 2898 YEWCQGPLLGTGAFSKCYQGRDVRTGLLMAVKQISISHSSIDKNEEIIKAVKTEVNLMIQLNHPNVLPLLGAMFSPTDNIISMFVRWMPGGSVASLLNQYSAFLEPVTLAYALQTARGLSYIHSNRILHRDLKGANLLLDSSGMRLRISDFGASARLSNGRDSNASDFKGQLLGTVAFMAPEVL---RGEEYGRSCDVWSFACCIIEMLTGSQPWRDRNHTNHLALMYTIASAEEPPKLPEQISADLTELLTDCLNRDPKKRPLSSKLESYRVFKH 3716
+ W +G +G G F K Y + TG LMA+K+I+I +K V E+ ++ + H N++ G + +I F+ G++ SL+ E +T + Q G+S +H + I+HRD+K AN+ L L++ DFG++ ++ + + +G +GT A+MAPEV + +GR+ D+WS C ++EM +G +PW + ++ +M+ + E+ P+ PE +S + + + CL DPK+R + +L + K+
Sbjct: 1187 FRWHRGIKIGQGRFGKVYTAVNNNTGELMAMKEIAIQPGET----RALKNVAEELKILEGIKHKNLVRYYGIEVHREELLI--FMELCSEGTLESLVELTGNLPEALTRRFTAQLLSGVSELHKHGIVHRDIKTANIFLVDGSNSLKLGDFGSAVKI-QAHTTVPGELQG-YVGTQAYMAPEVFTKTNSDGHGRAADIWSVGCVVVEMASGKRPWAQFD--SNFQIMFKVGMGEK-PQAPESLSQEGHDFIDHCLQHDPKRRLTAVELLEHNFCKY 1451
BLAST of MAP3K-1 vs. Ensembl Fly
Match: GckIII (gene:FBgn0266465 transcript:FBtr0083399) HSP 1 Score: 127.487 bits (319), Expect = 1.122e-29 Identity = 78/265 (29.43%), Postives = 132/265 (49.81%), Query Frame = 3
Query: 2922 LGTGAFSKCYQGRDVRTGLLMAVKQISISHSSIDKNEEIIKAVKTEVNLMIQLNHPNVLPLLGAMFSPTDNIISMFVRWMPGGSVASLLNQYSAFLEPVTLAYAL-QTARGLSYIHSNRILHRDLKGANLLLDSSGMRLRISDFGASARLSNGRDSNASDFKGQLLGTVAFMAPEVLRGEEYGRSCDVWSFACCIIEMLTGSQPWRDRNHTNHLALMYTIASAEEPPKLPEQISADLTELLTDCLNRDPKKRPLSSKLESYRVFK 3713
+G G+F + ++G D RT ++A+K I + + E+ I ++ E+ ++ Q + P V G+ T I M ++ GGS L+ S E + + L + +GL Y+HS R LHRD+K AN+LL G ++++DFG + +L +N + + +GT +MAPEV++ +Y D+WS IE+ G P N H + + PP+L + + + CLN+DP+ RP + +L Y K
Sbjct: 19 IGKGSFGEVFKGIDNRTQQVVAIKIIDLEEA-----EDEIDDIQQEIMVLSQCDSPYVTKYYGSFLKGTKLWIIM--EYLGGGSALDLMKAGS--FEEMHIGIILREVLKGLDYLHSERKLHRDIKAANVLLSEQG-DVKLADFGVAGQL-----TNTTSKRNTFVGTPFWMAPEVIKQSQYDAKADIWSLGITAIELAKGEPP----NSELHPMRVLFLIPKNNPPQLTGSYTKSFKDFVEACLNKDPENRPTAKELLKYPFIK 264
BLAST of MAP3K-1 vs. Ensembl Zebrafish
Match: map3k1 (mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase [Source:ZFIN;Acc:ZDB-GENE-090313-412]) HSP 1 Score: 309.686 bits (792), Expect = 1.990e-86 Identity = 145/286 (50.70%), Postives = 197/286 (68.88%), Query Frame = 3
Query: 2859 PGLGVFSSEYRSGYEWCQGPLLGTGAFSKCYQGRDVRTGLLMAVKQISISHSSIDKNEEIIKAVKTEVNLMIQLNHPNVLPLLGAMFSPTDNIISMFVRWMPGGSVASLLNQYSAFLEPVTLAYALQTARGLSYIHSNRILHRDLKGANLLLDSSGMRLRISDFGASARLSNGRDSNASDFKGQLLGTVAFMAPEVLRGEEYGRSCDVWSFACCIIEMLTGSQPWRDRNHTNHLALMYTIASAEEPPKLPEQISADLTELLTDCLNRDPKKRPLSSKLESYRVFKH 3716
PG YR G EW +G +G GAFS CYQ +DV TG LMAVKQ++ ++ + EE+++A++ E+ +M LNHP+++ +LGA N ++FV WM GGSV+ LLN+Y AF E V + Y Q RGL+Y+H N+I+HRD+KGANLL+DS+G RLRI+DFGA+ARL++ + + A +F+GQLLGT+AFMAPEVLRG++YGRSCDVWS C IIEM PW H+NHLAL++ IASA P +P +S L ++ CL P RP S +L + VF+H
Sbjct: 1018 PGHTKAKQPYREGNEWLKGQQIGLGAFSSCYQAQDVGTGTLMAVKQVTYVRNTSSEQEEVVEALREEIRMMGLLNHPHIIRMLGATCE--KNNYNLFVEWMAGGSVSHLLNKYGAFKEGVIINYTEQLLRGLAYLHENQIIHRDIKGANLLIDSTGQRLRIADFGAAARLAS-KGTGAGEFQGQLLGTIAFMAPEVLRGQQYGRSCDVWSVGCAIIEMSCAKPPWNAEKHSNHLALIFKIASATTAPSIPPHLSPGLRDVTLRCLELQPTDRPPSRELLKHPVFRH 1300 HSP 2 Score: 137.117 bits (344), Expect = 5.539e-32 Identity = 139/548 (25.36%), Postives = 230/548 (41.97%), Query Frame = 3
Query: 387 YRQSNIQEKLKIISQQNFCILPQCSPTSFTVCAGS-SSRYVVNIGPQXXXXXXXXXXXXNQHSFPCVHLLFIMCKVLQVHERDPLLLEKHLKNIEVDELFKRFNKRIKEKLNNPYRPNDKNCKNINHEEEHEGNTSRFGRDATSFGLQYKSVMKNMMAHVLEKCRNKNKHDCDEPRPNESLDEITCSICLQEMNIAQLLIFCH-NCSNEFHKKCILIWLKECKKNNEELTCPLCRKSW-PSDDISRDIVSPLEYGPSVA------------------DSNFFVPRSHSTATSFQHINHREITNIAXXXXXXXXXXXXXXINGSKHGFSVSSNHKPIGYCFSALVAEMLSSDMSDKREAGLRQVAEQTVQIVVSAGSAYSVEDNKVNCMSDTISTDIVSSMGGFTTGLMLKEAFRVIARLLDDTSYTLFVGALRAFREILGYLICRTESEVERMSRMISPVLCQLLRICGDNSQKKKAQMCLSALFELANGQEGGMALGREI-KKSSLPVTGWQRLAKFAIANH---HRFKAVHCYGRLSLLERLLDKF 1955
Y ++ + + +L Q P SF + S +++ V IGPQTC C + +F C+H+LF+M +V Q+ DPLL K LKN EV+ LF++++ R ++ P R S ++ S M N +H + + E E C ICL +M + L C C N+ H C+ IW +EC++N++ L CPLCR W P D S + S +E S A D +F +P+ QHI + T +A +P F + L S + RE LR+++ ++ A +S+ +S D+V ++ V++ + D Y ++V AL+ R +L Y C + SE R+ +++ PV+ +L C D + + +Q+ +S L EL GQ G +A+GREI K S+ + G + + + + ++A+ GRL L++RLL +F
Sbjct: 126 YSPEETSRRVNKVMRARLYLLQQIGPNSFLIGGDSPDNKFRVFIGPQTCSC--------GRGTF-CIHVLFVMLRVFQLEPSDPLLWRKTLKNFEVESLFQKYHNRRSSRIKAPSR---------------------------STIQKFVSRMSN--SHTSCTSSASPSSNESSMKDEE---EQMCPICLLDMLDEESLTVCEEGCRNKLHHHCMSIWAEECRRNHDPLICPLCRAKWKPHDFYSYEAPSTVESTTSPASSSSSSSSLHAESSRTGQDGDFSLPQ-----YGVQHIP-QTYTELA----------------------------EPWIKVFGLELVGCLFSRNWNIREMALRRLSHDVSGALLLANGEHSLAGAGAGAGLAEVSGDVV-----------VESCCSVLSMVCADPVYKVYVAALKTLRAMLVYTPCHSASERTRLQQLLRPVVETILVKCAD-ANSRTSQLSVSTLLELCKGQMGELAVGREILKAGSIGIGGVDYVLNCILGSKTEANNWQAL--LGRLCLIDRLLLEF 584
BLAST of MAP3K-1 vs. Ensembl Zebrafish
Match: map3k1 (mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase [Source:ZFIN;Acc:ZDB-GENE-090313-412]) HSP 1 Score: 310.071 bits (793), Expect = 2.474e-86 Identity = 145/286 (50.70%), Postives = 197/286 (68.88%), Query Frame = 3
Query: 2859 PGLGVFSSEYRSGYEWCQGPLLGTGAFSKCYQGRDVRTGLLMAVKQISISHSSIDKNEEIIKAVKTEVNLMIQLNHPNVLPLLGAMFSPTDNIISMFVRWMPGGSVASLLNQYSAFLEPVTLAYALQTARGLSYIHSNRILHRDLKGANLLLDSSGMRLRISDFGASARLSNGRDSNASDFKGQLLGTVAFMAPEVLRGEEYGRSCDVWSFACCIIEMLTGSQPWRDRNHTNHLALMYTIASAEEPPKLPEQISADLTELLTDCLNRDPKKRPLSSKLESYRVFKH 3716
PG YR G EW +G +G GAFS CYQ +DV TG LMAVKQ++ ++ + EE+++A++ E+ +M LNHP+++ +LGA N ++FV WM GGSV+ LLN+Y AF E V + Y Q RGL+Y+H N+I+HRD+KGANLL+DS+G RLRI+DFGA+ARL++ + + A +F+GQLLGT+AFMAPEVLRG++YGRSCDVWS C IIEM PW H+NHLAL++ IASA P +P +S L ++ CL P RP S +L + VF+H
Sbjct: 1050 PGHTKAKQPYREGNEWLKGQQIGLGAFSSCYQAQDVGTGTLMAVKQVTYVRNTSSEQEEVVEALREEIRMMGLLNHPHIIRMLGATCE--KNNYNLFVEWMAGGSVSHLLNKYGAFKEGVIINYTEQLLRGLAYLHENQIIHRDIKGANLLIDSTGQRLRIADFGAAARLAS-KGTGAGEFQGQLLGTIAFMAPEVLRGQQYGRSCDVWSVGCAIIEMSCAKPPWNAEKHSNHLALIFKIASATTAPSIPPHLSPGLRDVTLRCLELQPTDRPPSRELLKHPVFRH 1332 HSP 2 Score: 138.658 bits (348), Expect = 1.987e-32 Identity = 137/542 (25.28%), Postives = 234/542 (43.17%), Query Frame = 3
Query: 387 YRQSNIQEKLKIISQQNFCILPQCSPTSFTVCAGS-SSRYVVNIGPQXXXXXXXXXXXXNQHSFPCVHLLFIMCKVLQVHERDPLLLEKHLKNIEVDELFKRFNKRIKEKLNNPYRPNDKNCKNINHEEEHEGNTSRFGRDATSFGLQYKSVMKNMMAHVLEKCRNKNKHDCDEPRPNESLDEITCSICLQEMNIAQLLIFCH-NCSNEFHKKCILIWLKECKKNNEELTCPLCRKSWPSDDISRDIVSPLEYGPSVADSNFFVPRSHSTATSFQHINHREITNIAXXXXXXXXXXXXXXINGSKHG-FSVSS---NHKPIGY---------CFSALVAEMLSSDMSDKREAGLRQVAEQTVQIVVSAGSAYSVEDNKVNCMSDTISTDIVSSMGGFTTGLMLKEAFRVIARLLDDTSYTLFVGALRAFREILGYLICRTESEVERMSRMISPVLCQLLRICGDNSQKKKAQMCLSALFELANGQEGGMALGREI-KKSSLPVTGWQRLAKFAIANH---HRFKAVHCYGRLSLLERLLDKF 1955
Y ++ + + +L Q P SF + S +++ V IGPQTC C + +F C+H+LF+M +V Q+ DPLL K LKN EV+ LF++++ R ++ P R + ++ S M N +H + + E E C ICL +M + L C C N+ H C+ IW +EC++N++ L CPLCR W D F+ S+ ++ + R + A+S+S +SS + + + G FS+ H P Y F + L S + RE LR+++ ++ A +S+ +S D+V ++ V++ + D Y ++V AL+ R +L Y C + SE R+ +++ PV+ +L C D + + +Q+ +S L EL GQ G +A+GREI K S+ + G + + + + ++A+ GRL L++RLL +F
Sbjct: 138 YSPEETSRRVNKVMRARLYLLQQIGPNSFLIGGDSPDNKFRVFIGPQTCSC--------GRGTF-CIHVLFVMLRVFQLEPSDPLLWRKTLKNFEVESLFQKYHNRRSSRIKAPSRSTIQ---------------------------KFVSRMSN--SHTSCTSSASPSSNESSMKDEE---EQMCPICLLDMLDEESLTVCEEGCRNKLHHHCMSIWAEECRRNHDPLICPLCRAKWKPHD-------------------FY---SYEAPSTVESTTSRSQSQTAASSSSSSSSLHAESSRTGQDGDFSLPQYGVQHIPQTYTELAEPWIKVFGLELVGCLFSRNWNIREMALRRLSHDVSGALLLANGEHSLAGAGAGAGLAEVSGDVV-----------VESCCSVLSMVCADPVYKVYVAALKTLRAMLVYTPCHSASERTRLQQLLRPVVETILVKCAD-ANSRTSQLSVSTLLELCKGQMGELAVGREILKAGSIGIGGVDYVLNCILGSKTEANNWQAL--LGRLCLIDRLLLEF 602
BLAST of MAP3K-1 vs. Ensembl Zebrafish
Match: map3k1 (mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase [Source:ZFIN;Acc:ZDB-GENE-090313-412]) HSP 1 Score: 309.301 bits (791), Expect = 2.674e-86 Identity = 145/286 (50.70%), Postives = 197/286 (68.88%), Query Frame = 3
Query: 2859 PGLGVFSSEYRSGYEWCQGPLLGTGAFSKCYQGRDVRTGLLMAVKQISISHSSIDKNEEIIKAVKTEVNLMIQLNHPNVLPLLGAMFSPTDNIISMFVRWMPGGSVASLLNQYSAFLEPVTLAYALQTARGLSYIHSNRILHRDLKGANLLLDSSGMRLRISDFGASARLSNGRDSNASDFKGQLLGTVAFMAPEVLRGEEYGRSCDVWSFACCIIEMLTGSQPWRDRNHTNHLALMYTIASAEEPPKLPEQISADLTELLTDCLNRDPKKRPLSSKLESYRVFKH 3716
PG YR G EW +G +G GAFS CYQ +DV TG LMAVKQ++ ++ + EE+++A++ E+ +M LNHP+++ +LGA N ++FV WM GGSV+ LLN+Y AF E V + Y Q RGL+Y+H N+I+HRD+KGANLL+DS+G RLRI+DFGA+ARL++ + + A +F+GQLLGT+AFMAPEVLRG++YGRSCDVWS C IIEM PW H+NHLAL++ IASA P +P +S L ++ CL P RP S +L + VF+H
Sbjct: 1010 PGHTKAKQPYREGNEWLKGQQIGLGAFSSCYQAQDVGTGTLMAVKQVTYVRNTSSEQEEVVEALREEIRMMGLLNHPHIIRMLGATCE--KNNYNLFVEWMAGGSVSHLLNKYGAFKEGVIINYTEQLLRGLAYLHENQIIHRDIKGANLLIDSTGQRLRIADFGAAARLAS-KGTGAGEFQGQLLGTIAFMAPEVLRGQQYGRSCDVWSVGCAIIEMSCAKPPWNAEKHSNHLALIFKIASATTAPSIPPHLSPGLRDVTLRCLELQPTDRPPSRELLKHPVFRH 1292 HSP 2 Score: 128.257 bits (321), Expect = 3.242e-29 Identity = 139/548 (25.36%), Postives = 221/548 (40.33%), Query Frame = 3
Query: 387 YRQSNIQEKLKIISQQNFCILPQCSPTSFTVCAGS-SSRYVVNIGPQXXXXXXXXXXXXNQHSFPCVHLLFIMCKVLQVHERDPLLLEKHLKNIEVDELFKRFNKRIKEKLNNPYRPNDKNCKNINHEEEHEGNTSRFGRDATSFGLQYKSVMKNMMAHVLEKCRNKNKHDCDEPRPNESLDEITCSICLQEMNIAQLLIFCH-NCSNEFHKKCILIWLKECKKNNEELTCPLCRKSW-PSDDISRDIVSPLEYGPSVA------------------DSNFFVPRSHSTATSFQHINHREITNIAXXXXXXXXXXXXXXINGSKHGFSVSSNHKPIGYCFSALVAEMLSSDMSDKREAGLRQVAEQTVQIVVSAGSAYSVEDNKVNCMSDTISTDIVSSMGGFTTGLMLKEAFRVIARLLDDTSYTLFVGALRAFREILGYLICRTESEVERMSRMISPVLCQLLRICGDNSQKKKAQMCLSALFELANGQEGGMALGREI-KKSSLPVTGWQRLAKFAIANH---HRFKAVHCYGRLSLLERLLDKF 1955
Y ++ + + +L Q P SF + S +++ V IGPQTC C + +F C+H+LF+M +V Q+ DPLL K LKN EV L Y PN K +NI E G F +D +E C ICL +M + L C C N+ H C+ IW +EC++N++ L CPLCR W P D S + S +E S A D +F +P+ QHI + T +A +P F + L S + RE LR+++ ++ A +S+ +S D+V ++ V++ + D Y ++V AL+ R +L Y C + SE R+ +++ PV+ +L C D + + +Q+ +S L EL GQ G +A+GREI K S+ + G + + + + ++A+ GRL L++RLL +F
Sbjct: 138 YSPEETSRRVNKVMRARLYLLQQIGPNSFLIGGDSPDNKFRVFIGPQTCSC--------GRGTF-CIHVLFVMLRVFQLEPSDPLLWRKTLKNFEVRRL---------------YNPN-KAPQNIKWENSGRG----FMKDE---------------------------------------EEQMCPICLLDMLDEESLTVCEEGCRNKLHHHCMSIWAEECRRNHDPLICPLCRAKWKPHDFYSYEAPSTVESTTSPASSSSSSSSLHAESSRTGQDGDFSLPQ-----YGVQHIP-QTYTELA----------------------------EPWIKVFGLELVGCLFSRNWNIREMALRRLSHDVSGALLLANGEHSLAGAGAGAGLAEVSGDVV-----------VESCCSVLSMVCADPVYKVYVAALKTLRAMLVYTPCHSASERTRLQQLLRPVVETILVKCAD-ANSRTSQLSVSTLLELCKGQMGELAVGREILKAGSIGIGGVDYVLNCILGSKTEANNWQAL--LGRLCLIDRLLLEF 569
BLAST of MAP3K-1 vs. Ensembl Zebrafish
Match: map3k19 (mitogen-activated protein kinase kinase kinase 19 [Source:ZFIN;Acc:ZDB-GENE-081104-140]) HSP 1 Score: 181.415 bits (459), Expect = 2.545e-50 Identity = 100/276 (36.23%), Postives = 161/276 (58.33%), Query Frame = 3
Query: 2904 WCQGPLLGTGAFSKCYQGRDVRTGLLMAVKQISISHSSIDKNEEIIKAVKTEVNLMIQLNHPNVLPLLGAMFSPTDNIISMFVRWMPGGSVASLLNQYSAFLEPVTLAYALQTARGLSYIHSNRILHRDLKGANLLLDSSGMRLRISDFGASARLSNGRDSNASDFKGQLL----GTVAFMAPEVLRGEEYGRSCDVWSFACCIIEMLTGSQPWRDRNHTNHLALMYTIASAEE-PPKLPEQISADLTELLTDCLNRDPKKRPLSSKLESYRVFKH 3716
W +G +LG GA+ Y G + G L+AVKQ+++ S+ + E+ ++ EV+L+ L H N++ LG S +NI+S+F+ ++PGGS++++L Q+ E V + Y+ Q G++Y+H+NR++HRDLKG N++L +G+ +++ DFG + RLS + S S KG LL GT +MAPEV+ +GR D+WS C + EM TG P H N +A +Y I + P L + S D + + CL RD ++RP + +L + H
Sbjct: 21 WTKGEVLGKGAYGTVYCGLTSQ-GQLIAVKQVALDASTSEIAEKEYDRLEREVDLLKNLKHTNIVGFLGTALS--ENIVSIFMEYIPGGSISNILGQFGPLPEKVFVLYSQQILEGVAYLHANRVIHRDLKGNNIMLMPTGV-VKLIDFGCARRLSCLQTSTGS--KGDLLKSVHGTPYWMAPEVINETGHGRKSDIWSIGCTVFEMATGKPPLA---HMNKMAALYYIGARRGLMPSLSDDFSTDAKDFVQACLTRDQRQRPSAEELLRHPFISH 287
BLAST of MAP3K-1 vs. Ensembl Zebrafish
Match: map3k3 (mitogen-activated protein kinase kinase kinase 3 [Source:ZFIN;Acc:ZDB-GENE-070910-1]) HSP 1 Score: 187.578 bits (475), Expect = 2.206e-49 Identity = 101/263 (38.40%), Postives = 151/263 (57.41%), Query Frame = 3
Query: 2904 WCQGPLLGTGAFSKCYQGRDVRTGLLMAVKQISISHSSIDKNEEIIKAVKTEVNLMIQLNHPNVLPLLGAMFSPTDNIISMFVRWMPGGSVASLLNQYSAFLEPVTLAYALQTARGLSYIHSNRILHRDLKGANLLLDSSGMRLRISDFGASARLSNGRDSNASDFKGQLLGTVAFMAPEVLRGEEYGRSCDVWSFACCIIEMLTGSQPWRDRNHTNHLALMYTIASAEEPPKLPEQISADLTELLTDCLNRDPKKRPLSSKL 3692
W +G LLG GAF + Y DV TG +A KQ+ +S + ++E+ A++ E+ L+ L+H ++ G + + +++F+ +MPGGSV L Y A E VT Y Q G+SY+HSN I+HRD+KGAN+L DS+G +++ DFGAS RL +S + GT +M+PEV+ GE YGR DVWS C ++EMLT PW + +A ++ IA+ P+LP IS + L C+ + K RP + +L
Sbjct: 356 WRRGKLLGQGAFGRVYLCYDVDTGRELAAKQVHFDPASPETSKEV-SALECEIQLLKNLHHERIVQYYGCLRDHNEKTLTIFMEYMPGGSVKDQLKAYGALTENVTRKYTRQILEGMSYLHSNMIVHRDIKGANILRDSAG-NVKLGDFGASKRLQT--ICMSSTGVRSVTGTPYWMSPEVISGEGYGRKADVWSLGCTVVEMLTEKPPWAE---FEAMAAIFKIATQPTNPQLPSHISEHTRDFLR-CIFVEAKYRPSAEEL 610
BLAST of MAP3K-1 vs. Ensembl Xenopus
Match: slc2a1 (solute carrier family 2 (facilitated glucose transporter), member 1 [Source:Xenbase;Acc:XB-GENE-5755357]) HSP 1 Score: 304.679 bits (779), Expect = 2.345e-84 Identity = 142/285 (49.82%), Postives = 198/285 (69.47%), Query Frame = 3
Query: 2859 PGLGVFSSEYRSGYEWCQGPLLGTGAFSKCYQGRDVRTGLLMAVKQISISHSSIDKNEEIIKAVKTEVNLMIQLNHPNVLPLLGAMFSPTDNIISMFVRWMPGGSVASLLNQYSAFLEPVTLAYALQTARGLSYIHSNRILHRDLKGANLLLDSSGMRLRISDFGASARLSNGRDSNASDFKGQLLGTVAFMAPEVLRGEEYGRSCDVWSFACCIIEMLTGSQPWRDRNHTNHLALMYTIASAEEPPKLPEQISADLTELLTDCLNRDPKKRPLSSKLESYRVFK 3713
PG + YR EW +G +G GAFS CYQ +DV TG LMAVKQ++ ++ + E+++A++ E+ +M L+HPN++ +LGA ++ ++F+ WM GGSVA LL++Y AF E V + YA Q RGLSY+H N+I+HRD+KGANLL+DS+G RLRI+DFGA+ARL++ + + A +F+GQLLGT+AFMAPEVLRG++YGRSCDVWS C IIEM PW H+NHLAL++ IASA P +P +S L ++ CL P+ RP S +L + VF+
Sbjct: 1096 PGHTKARNHYREEMEWLKGQQIGLGAFSSCYQAQDVGTGTLMAVKQVTYVRNTSTEQGEVVEALREEIRMMSHLSHPNIIRMLGATCEKSN--YNLFIEWMAGGSVALLLSKYGAFKELVIINYAEQLLRGLSYLHENQIIHRDIKGANLLIDSTGQRLRIADFGAAARLAS-KGTGAGEFQGQLLGTIAFMAPEVLRGQQYGRSCDVWSLGCSIIEMACAKPPWNAEKHSNHLALIFKIASATTAPTIPPHLSPGLRDVTLRCLELQPQDRPPSRELLKHPVFR 1377 HSP 2 Score: 115.931 bits (289), Expect = 2.533e-25 Identity = 96/359 (26.74%), Postives = 160/359 (44.57%), Query Frame = 3
Query: 927 DEITCSICLQEMNIAQLLIFCH-NCSNEFHKKCILIWLKECKKNNEELTCPLCRKSWPSDDI-SRDIVSPLEYGPSV------ADSNFFVPRSHSTA--TSFQHINHREITNIAXXXXXXXXXXXXXXINGSKHGFSVSSNHKPIGYCFSALVAEMLSSDMSDKREAGLRQVAEQTVQIVVSAGSAYSVEDNKVNCMSDTISTDIVSSMGG----FTTGLMLKEAFRVIARLLDDTSYTLFVGALRAFREILGYLICRTESEVERMSRMISPVLCQLLRICGDNSQKKKAQMCLSALFELANGQEGGMALGREIKKS-SLPVTGWQRLAKFAIANHHRFKAVHC-YGRLSLLERLLDKF 1955
+E C ICL M + L C C N+ H C+ IW +EC++N E L CPLCR W S D S ++ P++ P + + P S TS ++ H + NI F+ +P F + L S + RE LR+++ ++ A + N N T T + ++ G + ++++ V++ + D Y ++V AL+ R +L Y C T +E +++ R+++PV+ +L C D + + +Q+ +S L EL GQ G +A+GREI KS S+ + G + +A GRL L++RLL +F
Sbjct: 311 EEQMCPICLLGMLDEESLTVCEEGCRNKLHHHCMSIWAEECRRNREPLICPLCRAKWRSQDFNSVELPGPVDSPPILRAVQQQSLQQLPTPGSQRRPQDTSL-NLTHYGVQNIP---------------------FAYKDMAEPWIQVFGMELVSCLFSRNWNIREMALRRLSHDVSGALLLANGEST--GNSCNSSGTTSGTSLNAASGSSQSTISGDVVVEACCSVLSMVCADPVYKVYVAALKTLRAMLVYTPCHTITERKKLQRLLNPVVETILVKCAD-ANSRTSQLSVSTLLELCKGQAGELAVGREILKSGSIGIGGVDYVLHCILATQAEPNNWQSLLGRLCLIDRLLLEF 644
BLAST of MAP3K-1 vs. Ensembl Xenopus
Match: slc2a1 (solute carrier family 2 (facilitated glucose transporter), member 1 [Source:Xenbase;Acc:XB-GENE-5755357]) HSP 1 Score: 304.679 bits (779), Expect = 3.436e-84 Identity = 142/285 (49.82%), Postives = 198/285 (69.47%), Query Frame = 3
Query: 2859 PGLGVFSSEYRSGYEWCQGPLLGTGAFSKCYQGRDVRTGLLMAVKQISISHSSIDKNEEIIKAVKTEVNLMIQLNHPNVLPLLGAMFSPTDNIISMFVRWMPGGSVASLLNQYSAFLEPVTLAYALQTARGLSYIHSNRILHRDLKGANLLLDSSGMRLRISDFGASARLSNGRDSNASDFKGQLLGTVAFMAPEVLRGEEYGRSCDVWSFACCIIEMLTGSQPWRDRNHTNHLALMYTIASAEEPPKLPEQISADLTELLTDCLNRDPKKRPLSSKLESYRVFK 3713
PG + YR EW +G +G GAFS CYQ +DV TG LMAVKQ++ ++ + E+++A++ E+ +M L+HPN++ +LGA ++ ++F+ WM GGSVA LL++Y AF E V + YA Q RGLSY+H N+I+HRD+KGANLL+DS+G RLRI+DFGA+ARL++ + + A +F+GQLLGT+AFMAPEVLRG++YGRSCDVWS C IIEM PW H+NHLAL++ IASA P +P +S L ++ CL P+ RP S +L + VF+
Sbjct: 1161 PGHTKARNHYREEMEWLKGQQIGLGAFSSCYQAQDVGTGTLMAVKQVTYVRNTSTEQGEVVEALREEIRMMSHLSHPNIIRMLGATCEKSN--YNLFIEWMAGGSVALLLSKYGAFKELVIINYAEQLLRGLSYLHENQIIHRDIKGANLLIDSTGQRLRIADFGAAARLAS-KGTGAGEFQGQLLGTIAFMAPEVLRGQQYGRSCDVWSLGCSIIEMACAKPPWNAEKHSNHLALIFKIASATTAPTIPPHLSPGLRDVTLRCLELQPQDRPPSRELLKHPVFR 1442 HSP 2 Score: 141.354 bits (355), Expect = 4.898e-33 Identity = 136/523 (26.00%), Postives = 222/523 (42.45%), Query Frame = 3
Query: 444 ILPQCSPTSFTVCAGS-SSRYVVNIGPQXXXXXXXXXXXXNQHSFPCVHLLFIMCKVLQVHERDPLLLEKHLKNIEVDELFKRFNKRIKEKLNNPYRPNDKNCKNINHEEEHEGNTSRFGRDATSFGLQYKSVMKNMMAHVLEKCRNKNKHDC--DEPRPNESLDEITCSICLQEMNIAQLLIFCH-NCSNEFHKKCILIWLKECKKNNEELTCPLCRKSWPSDDI-SRDIVSPLEYGPSV------ADSNFFVPRSHSTA--TSFQHINHREITNIAXXXXXXXXXXXXXXINGSKHGFSVSSNHKPIGYCFSALVAEMLSSDMSDKREAGLRQVAEQTVQIVVSAGSAYSVEDNKVNCMSDTISTDIVSSMGG----FTTGLMLKEAFRVIARLLDDTSYTLFVGALRAFREILGYLICRTESEVERMSRMISPVLCQLLRICGDNSQKKKAQMCLSALFELANGQEGGMALGREIKKS-SLPVTGWQRLAKFAIANHHRFKAVHC-YGRLSLLERLLDKF 1955
+L Q P SF + S ++Y V IGPQ C C + +F C+HLLF+M +V Q+ D +L K LKN EV+ LF+++ H +SR + + ++ S M + + DE +E C ICL M + L C C N+ H C+ IW +EC++N E L CPLCR W S D S ++ P++ P + + P S TS ++ H + NI F+ +P F + L S + RE LR+++ ++ A + N N T T + ++ G + ++++ V++ + D Y ++V AL+ R +L Y C T +E +++ R+++PV+ +L C D + + +Q+ +S L EL GQ G +A+GREI KS S+ + G + +A GRL L++RLL +F
Sbjct: 255 LLQQIGPNSFLIGGDSPDNKYRVFIGPQACSC--------GRGTF-CIHLLFVMLRVFQLEPSDTMLWRKALKNFEVESLFQKY---------------------------HSRRSSRIKAPSRNTIQKFVSRMSSSHTLSSSTTSTSSSDTSMKDE-------EEQMCPICLLGMLDEESLTVCEEGCRNKLHHHCMSIWAEECRRNREPLICPLCRAKWRSQDFNSVELPGPVDSPPILRAVQQQSLQQLPTPGSQRRPQDTSL-NLTHYGVQNIP---------------------FAYKDMAEPWIQVFGMELVSCLFSRNWNIREMALRRLSHDVSGALLLANGEST--GNSCNSSGTTSGTSLNAASGSSQSTISGDVVVEACCSVLSMVCADPVYKVYVAALKTLRAMLVYTPCHTITERKKLQRLLNPVVETILVKCAD-ANSRTSQLSVSTLLELCKGQAGELAVGREILKSGSIGIGGVDYVLHCILATQAEPNNWQSLLGRLCLIDRLLLEF 709
BLAST of MAP3K-1 vs. Ensembl Xenopus
Match: dennd1a (DENN domain containing 1A [Source:Xenbase;Acc:XB-GENE-5729862]) HSP 1 Score: 183.341 bits (464), Expect = 8.241e-48 Identity = 100/271 (36.90%), Postives = 151/271 (55.72%), Query Frame = 3
Query: 2904 WCQGPLLGTGAFSKCYQGRDVRTGLLMAVKQISISHSSIDKNEEIIKAVKTEVNLMIQLNHPNVLPLLGAMFSPTDNIISMFVRWMPGGSVASLLNQYSAFLEPVTLAYALQTARGLSYIHSNRILHRDLKGANLLLDSSGMRLRISDFGASARLSNGRDSNASDFKGQLLGTVAFMAPEVLRGEEYGRSCDVWSFACCIIEMLTGSQPWRDRNHTNHLALMYTIASAEEPPKLPEQISADLTELLTDCLNRDPKKRPLSSKLESYRVFKH 3716
W G LLG GAF + Y DV G +AVKQ+ S + ++E+ A++ E+ L+ H ++ G + PT+ +S+FV +MPGGS+ L Y A E VT Y Q +G+SY+H N I+HRD+KGAN+L DS+G +++ DFGAS R+ S + GT +M+PEV+ GE YGR DVWS AC ++EMLT PW + +A ++ IA+ P+LP+ +S + + + K+RP + +L + H
Sbjct: 354 WRLGKLLGRGAFGEVYLCYDVDKGRELAVKQVPFDPDSQETSKEV-NALECEIQLLKLHRHERIVQYYGCLRDPTERKLSIFVEYMPGGSIKDQLKAYGALTENVTRRYTRQILQGVSYLHGNMIVHRDIKGANILRDSAG-NVKLGDFGASKRIQTICMSGTG--IKSVTGTPYWMSPEVISGEGYGRKADVWSVACTVVEMLTEKPPW---SEYEAMAAIFKIATQPTKPRLPDTVSDACRDFMKQIFVEE-KRRPTAEELLRHLFVSH 616
BLAST of MAP3K-1 vs. Ensembl Xenopus
Match: dennd1a (DENN domain containing 1A [Source:Xenbase;Acc:XB-GENE-5729862]) HSP 1 Score: 182.956 bits (463), Expect = 1.197e-47 Identity = 100/271 (36.90%), Postives = 151/271 (55.72%), Query Frame = 3
Query: 2904 WCQGPLLGTGAFSKCYQGRDVRTGLLMAVKQISISHSSIDKNEEIIKAVKTEVNLMIQLNHPNVLPLLGAMFSPTDNIISMFVRWMPGGSVASLLNQYSAFLEPVTLAYALQTARGLSYIHSNRILHRDLKGANLLLDSSGMRLRISDFGASARLSNGRDSNASDFKGQLLGTVAFMAPEVLRGEEYGRSCDVWSFACCIIEMLTGSQPWRDRNHTNHLALMYTIASAEEPPKLPEQISADLTELLTDCLNRDPKKRPLSSKLESYRVFKH 3716
W G LLG GAF + Y DV G +AVKQ+ S + ++E+ A++ E+ L+ H ++ G + PT+ +S+FV +MPGGS+ L Y A E VT Y Q +G+SY+H N I+HRD+KGAN+L DS+G +++ DFGAS R+ S + GT +M+PEV+ GE YGR DVWS AC ++EMLT PW + +A ++ IA+ P+LP+ +S + + + K+RP + +L + H
Sbjct: 361 WRLGKLLGRGAFGEVYLCYDVDKGRELAVKQVPFDPDSQETSKEV-NALECEIQLLKLHRHERIVQYYGCLRDPTERKLSIFVEYMPGGSIKDQLKAYGALTENVTRRYTRQILQGVSYLHGNMIVHRDIKGANILRDSAG-NVKLGDFGASKRIQTICMSGTG--IKSVTGTPYWMSPEVISGEGYGRKADVWSVACTVVEMLTEKPPW---SEYEAMAAIFKIATQPTKPRLPDTVSDACRDFMKQIFVEE-KRRPTAEELLRHLFVSH 623
BLAST of MAP3K-1 vs. Ensembl Xenopus
Match: samd8 (sterile alpha motif domain containing 8 [Source:Xenbase;Acc:XB-GENE-1012742]) HSP 1 Score: 180.644 bits (457), Expect = 6.241e-47 Identity = 98/263 (37.26%), Postives = 149/263 (56.65%), Query Frame = 3
Query: 2904 WCQGPLLGTGAFSKCYQGRDVRTGLLMAVKQISISHSSIDKNEEIIKAVKTEVNLMIQLNHPNVLPLLGAMFSPTDNIISMFVRWMPGGSVASLLNQYSAFLEPVTLAYALQTARGLSYIHSNRILHRDLKGANLLLDSSGMRLRISDFGASARLSNGRDSNASDFKGQLLGTVAFMAPEVLRGEEYGRSCDVWSFACCIIEMLTGSQPWRDRNHTNHLALMYTIASAEEPPKLPEQISADLTELLTDCLNRDPKKRPLSSKL 3692
W +G LLG GAF + Y DV TG +A KQ+ S + ++E+ A++ E+ L+ L+H ++ G++ + +++F+ +MPGGSV L Y A E VT Y Q G+SY+HSN I+HRD+KGAN+L DS+G +++ DFGAS RL S + GT +M+PEV+ GE YGR DVWS C ++EMLT PW + +A ++ IA+ P+LP S + + L + ++RP + +L
Sbjct: 347 WRRGKLLGQGAFGRVYLCYDVDTGRELAAKQVQFDPDSPETSKEV-SALECEIQLLKNLHHDRIVQYYGSLRDKGEKTLTIFMEYMPGGSVKDQLKAYGALTENVTRRYTRQILEGVSYLHSNMIVHRDIKGANILRDSAG-NVKLGDFGASKRLQTICMSGTG--IRSVTGTPYWMSPEVISGEGYGRKADVWSLGCTVVEMLTEKPPWAE---YEAMAAIFKIATQPTNPQLPPNTSEQCRDFVKRILV-EARQRPTAEEL 601
BLAST of MAP3K-1 vs. Ensembl Mouse
Match: Map3k1 (mitogen-activated protein kinase kinase kinase 1 [Source:MGI Symbol;Acc:MGI:1346872]) HSP 1 Score: 309.301 bits (791), Expect = 1.196e-85 Identity = 143/285 (50.18%), Postives = 197/285 (69.12%), Query Frame = 3
Query: 2859 PGLGVFSSEYRSGYEWCQGPLLGTGAFSKCYQGRDVRTGLLMAVKQISISHSSIDKNEEIIKAVKTEVNLMIQLNHPNVLPLLGAMFSPTDNIISMFVRWMPGGSVASLLNQYSAFLEPVTLAYALQTARGLSYIHSNRILHRDLKGANLLLDSSGMRLRISDFGASARLSNGRDSNASDFKGQLLGTVAFMAPEVLRGEEYGRSCDVWSFACCIIEMLTGSQPWRDRNHTNHLALMYTIASAEEPPKLPEQISADLTELLTDCLNRDPKKRPLSSKLESYRVFK 3713
PG YR EW +G +G GAFS CYQ +DV TG LMAVKQ++ ++ + EE+++A++ E+ +M LNHPN++ +LGA ++ ++F+ WM GGSVA LL++Y AF E V + Y Q RGLSY+H N+I+HRD+KGANLL+DS+G RLRI+DFGA+ARL++ + + A +F+GQLLGT+AFMAPEVLRG++YGRSCDVWS C IIEM PW H+NHLAL++ IASA P +P +S L ++ CL P+ RP S +L + VF+
Sbjct: 1209 PGHTKAKQPYREDAEWLKGQQIGLGAFSSCYQAQDVGTGTLMAVKQVTYVRNTSSEQEEVVEALREEIRMMGHLNHPNIIRMLGATCEKSN--YNLFIEWMAGGSVAHLLSKYGAFKESVVINYTEQLLRGLSYLHENQIIHRDVKGANLLIDSTGQRLRIADFGAAARLAS-KGTGAGEFQGQLLGTIAFMAPEVLRGQQYGRSCDVWSVGCAIIEMACAKPPWNAEKHSNHLALIFKIASATTAPSIPSHLSPGLRDVALRCLELQPQDRPPSRELLKHPVFR 1490 HSP 2 Score: 104.76 bits (260), Expect = 5.510e-22 Identity = 77/253 (30.43%), Postives = 114/253 (45.06%), Query Frame = 3
Query: 387 YRQSNIQEKLKIISQQNFCILPQCSPTSFTVCAGS-SSRYVVNIGPQXXXXXXXXXXXXNQHSFPCVHLLFIMCKVLQVHERDPLLLEKHLKNIEVDELFKRFNKRIKEKLNNPYRPNDKNCKNINHEEEHEGNTSRFGRDATSFGLQYKSVMKNMMAHVLEKCRNKNKHDCDEPRPNESLDEITCSICLQEMNIAQLLIFCHN-CSNEFHKKCILIWLKECKKNNEELTCPLCRKSWPSDDI-SRDIVSPLE 1136
Y ++ + + +L Q P SF + S ++Y V IGPQ C C + +F C+HLLF+M +V Q+ DP+L K LKN EV+ LF++++ R ++ P R NT + ++ S M N H L + + E E C ICL M + L C + C N+ H C+ IW +EC++N E L CPLCR W S D S ++ SP+E
Sbjct: 294 YSPEETSRRVNKVMRARLYLLQQIGPNSFLIGGDSPDNKYRVFIGPQNCSC--------GRGAF-CIHLLFVMLRVFQLEPSDPMLWRKTLKNFEVESLFQKYHSRRSSRIKAPSR-----------------NTIQ----------KFVSRMSN--CHTLSSSSTSTSSSENSIKDEE---EQMCPICLLGMLDEESLTVCEDGCRNKLHHHCMSIWAEECRRNREPLICPLCRSKWRSHDFYSHELSSPVE 505 HSP 3 Score: 69.3218 bits (168), Expect = 3.960e-11 Identity = 43/142 (30.28%), Postives = 76/142 (53.52%), Query Frame = 3
Query: 1536 TGLMLKEAFRVIARLLDDTSYTLFVGALRAFREILGYLICRTESEVERMSRMISPVLCQLLRICGDNSQKKKAQMCLSALFELANGQEGGMALGREI-KKSSLPVTGWQRLAKFAIANHHRFKAVH-CYGRLSLLERLLDKF 1955
+G +++ V++ + D Y ++V AL+ R +L Y C + +E ++ R++ PV+ +L C D + + +Q+ +S + EL GQ G +A+GREI K S+ V G + + N GRL L++RLL +F
Sbjct: 624 SGDVVEACCSVLSIVCADPVYKVYVAALKTLRAMLVYTPCHSLAERIKLQRLLRPVVDTILVKCAD-ANSRTSQLSISTVLELCKGQAGELAVGREILKAGSIGVGGVDYVLSCILGNQAESNNWQELLGRLCLIDRLLLEF 764
BLAST of MAP3K-1 vs. Ensembl Mouse
Match: Map3k2 (mitogen-activated protein kinase kinase kinase 2 [Source:MGI Symbol;Acc:MGI:1346873]) HSP 1 Score: 187.578 bits (475), Expect = 2.280e-49 Identity = 108/286 (37.76%), Postives = 157/286 (54.90%), Query Frame = 3
Query: 2889 RSGYEWCQGPLLGTGAFSKCYQGRDVRTGLLMAVKQISISHSSIDKNEEIIKAVKTEVNLMIQLNHPNVLPLLGAMFSPTDNIISMFVRWMPGGSVASLLNQYSAFLEPVTLAYALQTARGLSYIHSNRILHRDLKGANLLLDSSGMRLRISDFGASARLSNGRDSNASDFKGQLLGTVAFMAPEVLRGEEYGRSCDVWSFACCIIEMLTGSQPWRDRNHTNHLALMYTIASAEEPPKLPEQISADLTELLTDCLNRDPKKRPLSSKLESYRVFKHLTS*MFFRYH 3746
R+ W G LLG GAF + Y DV TG +AVKQ+ + S + ++E+ A++ E+ L+ L H ++ G + P + +S+F+ +MPGGS+ L Y A E VT Y Q G+ Y+HSN I+HRD+KGAN+L DS+G +++ DFGAS RL S + GT +M+PEV+ GE YGR D+WS AC ++EMLT PW + +A ++ IA+ PKLP +S D T + + K RP + +L +H MF YH
Sbjct: 351 RAPTNWRLGKLLGQGAFGRVYLCYDVDTGRELAVKQVQFNPESPETSKEV-NALECEIQLLKNLLHERIVQYYGCLRDPQEKTLSIFMEYMPGGSIKDQLKAYGALTENVTRKYTRQILEGVHYLHSNMIVHRDIKGANILRDSTG-NIKLGDFGASKRLQTICLSGTG--MKSVTGTPYWMSPEVISGEGYGRKADIWSVACTVVEMLTEKPPWAE---FEAMAAIFKIATQPTNPKLPPHVS-DYTRDFLKRIFVEAKLRPSAEEL-----LRH----MFVHYH 619
BLAST of MAP3K-1 vs. Ensembl Mouse
Match: Map3k3 (mitogen-activated protein kinase kinase kinase 3 [Source:MGI Symbol;Acc:MGI:1346874]) HSP 1 Score: 182.57 bits (462), Expect = 1.271e-47 Identity = 103/266 (38.72%), Postives = 150/266 (56.39%), Query Frame = 3
Query: 2904 WCQGPLLGTGAFSKCYQGRDVRTGLLMAVKQISISHSSIDKNEEIIKAVKTEVNLMIQLNHPNVLPLLGAMFSPTDNIISMFVRWMPGGSVASLLNQYSAFLEPVTLAYALQTARGLSYIHSNRILHRDLKGANLLLDSSGMRLRISDFGASARLSNGRDSNASDFKGQLLGTVAFMAPEVLRGEEYGRSCDVWSFACCIIEMLTGSQPWRDRNHTNHLALMYTIASAEEPPKLPEQISADLTELLTDCLNR---DPKKRPLSSKL 3692
W +G LLG GAF + Y DV TG +A KQ+ S + ++E+ A++ E+ L+ L H ++ G + + I+++F+ +MPGGSV L Y A E VT Y Q G+SY+HSN I+HRD+KGAN+L DS+G +++ DFGAS RL S + GT +M+PEV+ GE YGR DVWS C ++EMLT PW + +A ++ IA+ P+LP IS E D L R + ++RP + +L
Sbjct: 362 WRRGKLLGQGAFGRVYLCYDVDTGRELASKQVQFDPDSPETSKEV-SALECEIQLLKNLQHERIVQYYGCLRDRAEKILTIFMEYMPGGSVKDQLKAYGALTESVTRKYTRQILEGMSYLHSNMIVHRDIKGANILRDSAG-NVKLGDFGASKRLQTICMSGTG--IRSVTGTPYWMSPEVISGEGYGRKADVWSLGCTVVEMLTEKPPWAE---YEAMAAIFKIATQPTNPQLPSHIS----EHGRDFLRRIFVEARQRPSAEEL 616
BLAST of MAP3K-1 vs. Ensembl Mouse
Match: Map3k19 (mitogen-activated protein kinase kinase kinase 19 [Source:MGI Symbol;Acc:MGI:1203481]) HSP 1 Score: 166.007 bits (419), Expect = 8.418e-43 Identity = 91/271 (33.58%), Postives = 149/271 (54.98%), Query Frame = 3
Query: 2904 WCQGPLLGTGAFSKCYQGRDVRTGLLMAVKQISISHSSIDKNEEIIKAVKTEVNLMIQLNHPNVLPLLGAMFSPTDNIISMFVRWMPGGSVASLLNQYSAFLEPVTLAYALQTARGLSYIHSNRILHRDLKGANLLLDSSGMRLRISDFGASARLS-NGRDSNASDFKGQLLGTVAFMAPEVLRGEEYGRSCDVWSFACCIIEMLTGSQPWRDRNHTNHLALMYTIASAEEPPKLPEQISADLTELLTDCLNRDPKKRPLSSKLESYRVFK 3713
W +G +LG GA+ Y G G L+AVKQ+++ S E+ + ++ EV+L+ L H N++ LG +N +S+F+ ++PGGS++S++N++ E V Y Q +G++Y+H N ++HRD+KG N++L +G+ +++ DFG + RL+ G + SD + GT +MAPEV+ YGR D+WS C + EM TG P + A+ Y A P LP + S + + CL RD +RP + +L + K
Sbjct: 248 WTKGEILGRGAYGTVYCGL-TSLGQLIAVKQVALDTSDKLATEKEYRKLQEEVDLLKALKHVNIVAYLGTCLE--ENTLSIFMEFVPGGSISSIINRFGPLPEMVFCKYTRQILQGVAYLHDNCVVHRDIKGNNVMLMPTGI-IKLIDFGCAKRLAWAGLNGTHSDMLKSMRGTPYWMAPEVINESGYGRKSDIWSIGCTVFEMATGKPPLASMDRMA--AMFYIGAHRGLMPPLPARFSEPAADFVRLCLTRDQHERPSALQLLKHSFLK 512
BLAST of MAP3K-1 vs. Ensembl Mouse
Match: Map3k19 (mitogen-activated protein kinase kinase kinase 19 [Source:MGI Symbol;Acc:MGI:1203481]) HSP 1 Score: 166.392 bits (420), Expect = 6.862e-41 Identity = 91/271 (33.58%), Postives = 149/271 (54.98%), Query Frame = 3
Query: 2904 WCQGPLLGTGAFSKCYQGRDVRTGLLMAVKQISISHSSIDKNEEIIKAVKTEVNLMIQLNHPNVLPLLGAMFSPTDNIISMFVRWMPGGSVASLLNQYSAFLEPVTLAYALQTARGLSYIHSNRILHRDLKGANLLLDSSGMRLRISDFGASARLS-NGRDSNASDFKGQLLGTVAFMAPEVLRGEEYGRSCDVWSFACCIIEMLTGSQPWRDRNHTNHLALMYTIASAEEPPKLPEQISADLTELLTDCLNRDPKKRPLSSKLESYRVFK 3713
W +G +LG GA+ Y G G L+AVKQ+++ S E+ + ++ EV+L+ L H N++ LG +N +S+F+ ++PGGS++S++N++ E V Y Q +G++Y+H N ++HRD+KG N++L +G+ +++ DFG + RL+ G + SD + GT +MAPEV+ YGR D+WS C + EM TG P + A+ Y A P LP + S + + CL RD +RP + +L + K
Sbjct: 1044 WTKGEILGRGAYGTVYCGL-TSLGQLIAVKQVALDTSDKLATEKEYRKLQEEVDLLKALKHVNIVAYLGTCLE--ENTLSIFMEFVPGGSISSIINRFGPLPEMVFCKYTRQILQGVAYLHDNCVVHRDIKGNNVMLMPTGI-IKLIDFGCAKRLAWAGLNGTHSDMLKSMRGTPYWMAPEVINESGYGRKSDIWSIGCTVFEMATGKPPLASMDRM--AAMFYIGAHRGLMPPLPARFSEPAADFVRLCLTRDQHERPSALQLLKHSFLK 1308
BLAST of MAP3K-1 vs. UniProt/SwissProt
Match: sp|P53349|M3K1_MOUSE (Mitogen-activated protein kinase kinase kinase 1 OS=Mus musculus OX=10090 GN=Map3k1 PE=1 SV=3) HSP 1 Score: 309.301 bits (791), Expect = 6.380e-85 Identity = 143/285 (50.18%), Postives = 197/285 (69.12%), Query Frame = 3
Query: 2859 PGLGVFSSEYRSGYEWCQGPLLGTGAFSKCYQGRDVRTGLLMAVKQISISHSSIDKNEEIIKAVKTEVNLMIQLNHPNVLPLLGAMFSPTDNIISMFVRWMPGGSVASLLNQYSAFLEPVTLAYALQTARGLSYIHSNRILHRDLKGANLLLDSSGMRLRISDFGASARLSNGRDSNASDFKGQLLGTVAFMAPEVLRGEEYGRSCDVWSFACCIIEMLTGSQPWRDRNHTNHLALMYTIASAEEPPKLPEQISADLTELLTDCLNRDPKKRPLSSKLESYRVFK 3713
PG YR EW +G +G GAFS CYQ +DV TG LMAVKQ++ ++ + EE+++A++ E+ +M LNHPN++ +LGA ++ ++F+ WM GGSVA LL++Y AF E V + Y Q RGLSY+H N+I+HRD+KGANLL+DS+G RLRI+DFGA+ARL++ + + A +F+GQLLGT+AFMAPEVLRG++YGRSCDVWS C IIEM PW H+NHLAL++ IASA P +P +S L ++ CL P+ RP S +L + VF+
Sbjct: 1209 PGHTKAKQPYREDAEWLKGQQIGLGAFSSCYQAQDVGTGTLMAVKQVTYVRNTSSEQEEVVEALREEIRMMGHLNHPNIIRMLGATCEKSN--YNLFIEWMAGGSVAHLLSKYGAFKESVVINYTEQLLRGLSYLHENQIIHRDVKGANLLIDSTGQRLRIADFGAAARLAS-KGTGAGEFQGQLLGTIAFMAPEVLRGQQYGRSCDVWSVGCAIIEMACAKPPWNAEKHSNHLALIFKIASATTAPSIPSHLSPGLRDVAVRCLELQPQDRPPSRELLKHPVFR 1490 HSP 2 Score: 95.9005 bits (237), Expect = 2.075e-18 Identity = 74/255 (29.02%), Postives = 111/255 (43.53%), Query Frame = 3
Query: 387 YRQSNIQEKLKIISQQNFCILPQCSPTSFTVCAGS-SSRYVVNIGPQXXXXXXXXXXXXNQHSFPCVHLLFIMCKVLQVHERDPLLLEKHLKNIEVDELFKRFNKRIKEKLNNPYRPNDKNCKNINHEEEHEGNTSRFGRDATSFGLQYKSVMKNMMAHVLEKCRNKNKHDC--DEPRPNESLDEITCSICLQEMNIAQLLIFCHN-CSNEFHKKCILIWLKECKKNNEELTCPLCRKSWPSDDI-SRDIVSPLE 1136
Y ++ + + +L Q P SF + S ++Y V IGPQ C C + +F C+HLLF+M +V Q+ DP+L K LKN EV+ LF+++ H +SR + + ++ S M N + + DE +E C ICL M + L C + C N+ H C+ IW +EC++N E L CPLCR W S D S ++ SP+E
Sbjct: 294 YSPEETSRRVNKVMRARLYLLQQIGPNSFLIGGDSPDNKYRVFIGPQNCSC--------GRGAF-CIHLLFVMLRVFQLEPSDPMLWRKTLKNFEVESLFQKY---------------------------HSRRSSRIKAPSRNTIQKFVSRMSNSHTLSSSSTSTSSSENSIKDE-------EEQMCPICLLGMLDEESLTVCEDGCRNKLHHHCMSIWAEECRRNREPLICPLCRSKWRSHDFYSHELSSPVE 505 HSP 3 Score: 68.9366 bits (167), Expect = 3.118e-10 Identity = 43/142 (30.28%), Postives = 76/142 (53.52%), Query Frame = 3
Query: 1536 TGLMLKEAFRVIARLLDDTSYTLFVGALRAFREILGYLICRTESEVERMSRMISPVLCQLLRICGDNSQKKKAQMCLSALFELANGQEGGMALGREI-KKSSLPVTGWQRLAKFAIANHHRFKAVH-CYGRLSLLERLLDKF 1955
+G +++ V++ + D Y ++V AL+ R +L Y C + +E ++ R++ PV+ +L C D + + +Q+ +S + EL GQ G +A+GREI K S+ V G + + N GRL L++RLL +F
Sbjct: 624 SGDVVEACCSVLSIVCADPVYKVYVAALKTLRAMLVYTPCHSLAERIKLQRLLRPVVDTILVKCAD-ANSRTSQLSISTVLELCKGQAGELAVGREILKAGSIGVGGVDYVLSCILGNQAESNNWQELLGRLCLIDRLLLEF 764
BLAST of MAP3K-1 vs. UniProt/SwissProt
Match: sp|Q13233|M3K1_HUMAN (Mitogen-activated protein kinase kinase kinase 1 OS=Homo sapiens OX=9606 GN=MAP3K1 PE=1 SV=4) HSP 1 Score: 308.916 bits (790), Expect = 1.045e-84 Identity = 143/285 (50.18%), Postives = 197/285 (69.12%), Query Frame = 3
Query: 2859 PGLGVFSSEYRSGYEWCQGPLLGTGAFSKCYQGRDVRTGLLMAVKQISISHSSIDKNEEIIKAVKTEVNLMIQLNHPNVLPLLGAMFSPTDNIISMFVRWMPGGSVASLLNQYSAFLEPVTLAYALQTARGLSYIHSNRILHRDLKGANLLLDSSGMRLRISDFGASARLSNGRDSNASDFKGQLLGTVAFMAPEVLRGEEYGRSCDVWSFACCIIEMLTGSQPWRDRNHTNHLALMYTIASAEEPPKLPEQISADLTELLTDCLNRDPKKRPLSSKLESYRVFK 3713
PG YR EW +G +G GAFS CYQ +DV TG LMAVKQ++ ++ + EE+++A++ E+ +M LNHPN++ +LGA ++ ++F+ WM GGSVA LL++Y AF E V + Y Q RGLSY+H N+I+HRD+KGANLL+DS+G RLRI+DFGA+ARL++ + + A +F+GQLLGT+AFMAPEVLRG++YGRSCDVWS C IIEM PW H+NHLAL++ IASA P +P +S L ++ CL P+ RP S +L + VF+
Sbjct: 1228 PGHTKAKQPYREDTEWLKGQQIGLGAFSSCYQAQDVGTGTLMAVKQVTYVRNTSSEQEEVVEALREEIRMMSHLNHPNIIRMLGATCEKSN--YNLFIEWMAGGSVAHLLSKYGAFKESVVINYTEQLLRGLSYLHENQIIHRDVKGANLLIDSTGQRLRIADFGAAARLAS-KGTGAGEFQGQLLGTIAFMAPEVLRGQQYGRSCDVWSVGCAIIEMACAKPPWNAEKHSNHLALIFKIASATTAPSIPSHLSPGLRDVALRCLELQPQDRPPSRELLKHPVFR 1509 HSP 2 Score: 70.8626 bits (172), Expect = 9.034e-11 Identity = 43/142 (30.28%), Postives = 76/142 (53.52%), Query Frame = 3
Query: 1536 TGLMLKEAFRVIARLLDDTSYTLFVGALRAFREILGYLICRTESEVERMSRMISPVLCQLLRICGDNSQKKKAQMCLSALFELANGQEGGMALGREI-KKSSLPVTGWQRLAKFAIANHHRFKAVH-CYGRLSLLERLLDKF 1955
+G +++ V++ + D Y ++V AL+ R +L Y C + +E ++ R++ PV+ +L C D + + +Q+ +S L EL GQ G +A+GREI K S+ + G + + N GRL L++RLL +F
Sbjct: 628 SGDVVEACCSVLSMVCADPVYKVYVAALKTLRAMLVYTPCHSLAERIKLQRLLQPVVDTILVKCAD-ANSRTSQLSISTLLELCKGQAGELAVGREILKAGSIGIGGVDYVLNCILGNQTESNNWQELLGRLCLIDRLLLEF 768 HSP 3 Score: 65.855 bits (159), Expect = 2.983e-9 Identity = 30/72 (41.67%), Postives = 42/72 (58.33%), Query Frame = 3
Query: 927 DEITCSICLQEMNIAQLLIFCHN-CSNEFHKKCILIWLKECKKNNEELTCPLCRKSWPSDDI-SRDIVSPLE 1136
+E C ICL M + L C + C N+ H C+ IW +EC++N E L CPLCR W S D S ++ SP++
Sbjct: 439 EEQMCPICLLGMLDEESLTVCEDGCRNKLHHHCMSIWAEECRRNREPLICPLCRSKWRSHDFYSHELSSPVD 510
BLAST of MAP3K-1 vs. UniProt/SwissProt
Match: sp|Q62925|M3K1_RAT (Mitogen-activated protein kinase kinase kinase 1 OS=Rattus norvegicus OX=10116 GN=Map3k1 PE=1 SV=1) HSP 1 Score: 306.99 bits (785), Expect = 3.890e-84 Identity = 142/285 (49.82%), Postives = 197/285 (69.12%), Query Frame = 3
Query: 2859 PGLGVFSSEYRSGYEWCQGPLLGTGAFSKCYQGRDVRTGLLMAVKQISISHSSIDKNEEIIKAVKTEVNLMIQLNHPNVLPLLGAMFSPTDNIISMFVRWMPGGSVASLLNQYSAFLEPVTLAYALQTARGLSYIHSNRILHRDLKGANLLLDSSGMRLRISDFGASARLSNGRDSNASDFKGQLLGTVAFMAPEVLRGEEYGRSCDVWSFACCIIEMLTGSQPWRDRNHTNHLALMYTIASAEEPPKLPEQISADLTELLTDCLNRDPKKRPLSSKLESYRVFK 3713
PG + YR EW +G +G GAFS CYQ +DV TG LMAVKQ++ ++ + EE+++A++ E+ +M LNHPN++ +LGA ++ ++F+ WM G SVA LL++Y AF E V + Y Q RGLSY+H N+I+HRD+KGANLL+DS+G RLRI+DFGA+ARL++ + + A +F+GQLLGT+AFMAPEVLRG++YGRSCDVWS C IIEM PW H+NHLAL++ IASA P +P +S L ++ CL P+ RP S +L + VF+
Sbjct: 1209 PGHTKANEPYREDTEWLKGQQIGLGAFSSCYQAQDVGTGTLMAVKQVTYVRNTSSEQEEVVEALREEIRMMSHLNHPNIIRMLGATCEKSN--YNLFIEWMAGASVAHLLSKYGAFKESVVINYTEQLLRGLSYLHENQIIHRDVKGANLLIDSTGQRLRIADFGAAARLAS-KGTGAGEFQGQLLGTIAFMAPEVLRGQQYGRSCDVWSVGCAIIEMACAKPPWNAEKHSNHLALIFKIASATTAPSIPSHLSPGLRDVALRCLELQPQDRPPSRELLKHPVFR 1490 HSP 2 Score: 103.605 bits (257), Expect = 7.915e-21 Identity = 76/253 (30.04%), Postives = 114/253 (45.06%), Query Frame = 3
Query: 387 YRQSNIQEKLKIISQQNFCILPQCSPTSFTVCAGS-SSRYVVNIGPQXXXXXXXXXXXXNQHSFPCVHLLFIMCKVLQVHERDPLLLEKHLKNIEVDELFKRFNKRIKEKLNNPYRPNDKNCKNINHEEEHEGNTSRFGRDATSFGLQYKSVMKNMMAHVLEKCRNKNKHDCDEPRPNESLDEITCSICLQEMNIAQLLIFCHN-CSNEFHKKCILIWLKECKKNNEELTCPLCRKSWPSDDI-SRDIVSPLE 1136
Y ++ + + +L Q P SF + S ++Y V IGPQ C C + +F C+HLLF+M +V Q+ DP+L K LKN EV+ LF++++ R ++ P R NT + ++ S M N H L + + E E C ICL M + L C + C N+ H C+ IW +EC++N E L CPLCR W S D S ++ SP++
Sbjct: 289 YSPEETSRRVNKVMRARLYLLQQIGPNSFLIGGDSPDNKYRVFIGPQNCSC--------GRGTF-CIHLLFVMLRVFQLEPSDPMLWRKTLKNFEVESLFQKYHSRRSSRIKAPSR-----------------NTIQ----------KFVSRMSN--CHTLSSSSTSTSSSENSIKDEE---EQMCPICLLGMLDEESLTVCEDGCRNKLHHHCMSIWAEECRRNREPLICPLCRSKWRSHDFYSHELSSPVD 500 HSP 3 Score: 68.9366 bits (167), Expect = 3.253e-10 Identity = 45/134 (33.58%), Postives = 72/134 (53.73%), Query Frame = 3
Query: 1554 EAF-RVIARLLDDTSYTLFVGALRAFREILGYLICRTESEVERMSRMISPVLCQLLRICGDNSQKKKAQMCLSALFELANGQEGGMALGREI-KKSSLPVTGWQRLAKFAIANHHRFKAVH-CYGRLSLLERLL 1946
EAF V++ + D Y ++V AL+ R +L Y C + +E ++ R++ PV+ +L C D + + +Q+ +S L EL GQ G +A+GREI K S+ V G + + N GRL L++RLL
Sbjct: 624 EAFCSVLSIVCADPVYKVYVAALKTLRAMLVYTPCHSLAERIKLQRLLRPVVDTILVKCAD-ANSRTSQLSISTLLELCKGQAGELAVGREILKAGSIGVGGVDYVLSCILGNQAESNNWQELLGRLCLIDRLL 756
BLAST of MAP3K-1 vs. UniProt/SwissProt
Match: sp|O22042|M3K3_ARATH (Mitogen-activated protein kinase kinase kinase 3 OS=Arabidopsis thaliana OX=3702 GN=ANP3 PE=1 SV=1) HSP 1 Score: 198.364 bits (503), Expect = 7.677e-52 Identity = 113/330 (34.24%), Postives = 187/330 (56.67%), Query Frame = 3
Query: 2805 QTNSMDRKDSLDIESQPPPGLGVFSSEYRSGYEWCQGPLLGTGAFSKCYQGRDVRTGLLMAVKQISISHSSI--DKNEEIIKAVKTEVNLMIQLNHPNVLPLLGAMFSPTDNIISMFVRWMPGGSVASLLNQYSAFLEPVTLAYALQTARGLSYIHSNRILHRDLKGANLLLDSSGMRLRISDFGASARLSNGRDSNASDFKGQLLGTVAFMAPEVLRGEEYGRSCDVWSFACCIIEMLTGSQPWRDRNHTNHLALMYTIASAEEPPKLPEQISADLTELLTDCLNRDPKKRPLSSKLESYRVFKH--LTS*MFFRYHQYRALSNSISFC 3782
+ NS R + + S+PPPGL E W +G L+G GAF + Y G ++ +G L+A+KQ+ I+ SS +K + I+ ++ EV L+ L+HPN++ LG + + +++ + ++PGGS++SLL ++ +F EPV + Y Q GL Y+H+N I+HRD+KGAN+L+D+ G +R++DFGAS ++ N + + GT +MAPEV+ + S D+WS C +IEM TG PW ++ A + I + P +PE +S + + L CL+++P S +L + + +H +T R Y A NS++ C
Sbjct: 35 KINSSIRSSRIGLFSKPPPGLPAPRKEEAPSIRWRKGELIGCGAFGRVYMGMNLDSGELLAIKQVLIAPSSASKEKTQGHIRELEEEVQLLKNLSHPNIVRYLGTVRE--SDSLNILMEFVPGGSISSLLEKFGSFPEPVIIMYTKQLLLGLEYLHNNGIMHRDIKGANILVDNKGC-IRLADFGASKKVVELATVNGAK---SMKGTPYWMAPEVILQTGHSFSADIWSVGCTVIEMATGKPPWSEQYQ--QFAAVLHIGRTKAHPPIPEDLSPEAKDFLMKCLHKEP-----SLRLSATELLQHPFVTG---KRQEPYPAYRNSLTEC 348
BLAST of MAP3K-1 vs. UniProt/SwissProt
Match: sp|Q9FZ36|M3K2_ARATH (Mitogen-activated protein kinase kinase kinase 2 OS=Arabidopsis thaliana OX=3702 GN=ANP2 PE=2 SV=1) HSP 1 Score: 197.208 bits (500), Expect = 1.764e-51 Identity = 109/306 (35.62%), Postives = 180/306 (58.82%), Query Frame = 3
Query: 2784 FRKILAEQTNSMDRKDSLDIESQPPPGLGVFSSEYRSGYEWCQGPLLGTGAFSKCYQGRDVRTGLLMAVKQISISH--SSIDKNEEIIKAVKTEVNLMIQLNHPNVLPLLGAMFSPTDNIISMFVRWMPGGSVASLLNQYSAFLEPVTLAYALQTARGLSYIHSNRILHRDLKGANLLLDSSGMRLRISDFGASARLSN-GRDSNASDFKGQLLGTVAFMAPEVLRGEEYGRSCDVWSFACCIIEMLTGSQPWRDRNHTNHLALMYTIASAEEPPKLPEQISADLTELLTDCLNRDPKKRPLSSKL 3692
F +LA++ S RK + +SQ PP + + W +G L+G GAF Y G ++ +G L+AVKQ+ I+ +S +K + I+ ++ EV L+ L+HPN++ LG + D +++ + ++PGGS++SLL ++ AF E V Y Q GL Y+H++ I+HRD+KGAN+L+D+ G ++++DFGAS +++ S A K GT +MAPEV+ + S D+WS C +IEM+TG PW + +A ++ I + + P +P+ IS+D + L CL ++P RP +S+L
Sbjct: 30 FPSLLADKITSCIRKSMVFAKSQSPPNNSTV--QIKPPIRWRKGQLIGRGAFGTVYMGMNLDSGELLAVKQVLITSNCASKEKTQAHIQELEEEVKLLKNLSHPNIVRYLGTVRE--DETLNILLEFVPGGSISSLLEKFGAFPESVVRTYTNQLLLGLEYLHNHAIMHRDIKGANILVDNQGC-IKLADFGASKQVAELATISGAKSMK----GTPYWMAPEVILQTGHSFSADIWSVGCTVIEMVTGKAPWSQQ--YKEIAAIFHIGTTKSHPPIPDNISSDANDFLLKCLQQEPNLRPTASEL 324
BLAST of MAP3K-1 vs. TrEMBL
Match: A0A224AC19 (Mitogen-activated protein kinase kinase kinase 1 OS=Dugesia japonica OX=6161 GN=MEKK1 PE=2 SV=1) HSP 1 Score: 1779.22 bits (4607), Expect = 0.000e+0 Identity = 886/1042 (85.03%), Postives = 948/1042 (90.98%), Query Frame = 3
Query: 600 MCKVLQVHERDPLLLEKHLKNIEVDELFKRFNKRIKEKLNNPYRPNDKNCKNINHEEEHEGNTSRFGRDATSFGLQYKSVMKNMMAHVLEKCRNKNKHDCDEPRPNESLDEITCSICLQEMNIAQLLIFCHNCSNEFHKKCILIWLKECKKNNEELTCPLCRKSWPSDDISRDIVSPLEYGPSVADSNFFVPRSHSTATSFQHINHREITNIAXXXXXXXXXXXXXXINGSKHGFSVSSNHKPIGYCFSALVAEMLSSDMSDKREAGLRQVAEQTVQIVVSAGSAYSVEDNKVNCMSDTISTDIVSSMGGFTTGLMLKEAFRVIARLLDDTSYTLFVGALRAFREILGYLICRTESEVERMSRMISPVLCQLLRICGDNSQKKKAQMCLSALFELANGQEGGMALGREIKKSSLPVTGWQRLAKFAIANHHRFKAVHCYGRLSLLERLLDKFELTLDILRKLLEFVTSQLLLMHRSMHLLNSFDSGKMDVLETTDVDTGLSTSDIRLLSGQRLQKLAKILFINTAKLMMSKLKFNGWSSHDVYVELWKDLNRLPQPWKEKFMIKLKIPWEKFINVELTEVDKSLQNREKKRPEVTPATVTPSCVSKSYRISKRYSQSKPVGAASKIGGIQSANSVNSLKVRTGSVSQTIRSASSGSCRISPFIRITPEPAYDAVPLSESEDDISHETSSVFFSELAIHNSIYGHQFGLQXXXXXXXXXXXXMKRTNAIFRKILAEQTNSMDRKDSLDIESQPPPGLGVFSSEYRSGYEWCQGPLLGTGAFSKCYQGRDVRTGLLMAVKQISISHSSIDKNEEIIKAVKTEVNLMIQLNHPNVLPLLGAMFSPTDNIISMFVRWMPGGSVASLLNQYSAFLEPVTLAYALQTARGLSYIHSNRILHRDLKGANLLLDSSGMRLRISDFGASARLSNGRDSNASDFKGQLLGTVAFMAPEVLRGEEYGRSCDVWSFACCIIEMLTGSQPWRDRNHTNHLALMYTIASAEEPPKLPEQISADLTELLTDCLNRDPKKRPLSSKLESYRVFKHLTS 3725
MCKVLQVHERDPLLL +LK +EV+ELF+RF+KR KEKL+NPYRPNDK+CKN NHE++ EGNTSRFGR +KNK D +EP PNES+DEITCSICLQEMN AQLL FC NCSNEFHKKCILIWLKECKKN+E LTCPLCRKSWPS+D +RD+ SPLEYGP++ DSN FVPRSHST FQHINHREITN+ASSTSDLTSSNFSFNINGSKH F++ SNHKP+G+CFS VA+MLSSDM DKREA LRQVAEQTVQIVVSAGSAYSVEDNK+NCMS TISTDIVSSMGGFTTGLMLKEAFRVIA+LLDDT YTLF+GALRAFREILGYLICRTESEVERMSRMISPVLCQLLRICGD+SQKKKAQM LSALFELANGQEGGMALGREIKK+SLPVTGWQRLAKFAI+NHHRFKA+HCYGRLSLLERLLDKFELTL+ILRKLLEFVT QLLLMHRS+HLLNSFDS K+D LETTDVDTGLST+DIRLLSGQRLQKLAKILFINTAKL++SKLKF G+S HD Y+EL KDL+++PQPWK+KF+IKLKIP + N E E+D S N+EKK+ E + TVTP VSKSYRISKRYSQ KPVG A+KIG Q NSVNSLK+R GS++Q+IRSASSGSCRISPFIRITPEPAYDAVPLSESEDDISHETSS FFSELAIHNSIYGHQFGLQESSSDERNEEEE+ +TN IFRKIL EQ+N+ ++KD LDIESQPPPGLGVFSSEYRSGYEWCQGPLLGTGAFSKCYQGRDVRTGLLMAVKQISISHS IDKNEEIIKAVKTEVNLMIQLNHPNVLPLLGA+FSP+DN ISMFVRWMPGGSVASLL YSAFLEPVTLAYALQTARGLSYIHSNRILHRDLKGANLLLDSSGMRLRISDFGASARLSNGRDSNASDFKGQLLGTVAFMAPEVLRGEEYGRSCDVWSFACCIIEMLTGSQPWRDRNHTNHLALMYTIASAEEPPKLPEQISADLTELLTDCLNRDPKKRPLSSKLESYRVFKHLTS
Sbjct: 1 MCKVLQVHERDPLLLSNNLKVVEVEELFQRFHKRRKEKLSNPYRPNDKHCKNSNHEDDVEGNTSRFGR-------------------------SKNKPDGNEPHPNESMDEITCSICLQEMNTAQLLKFCQNCSNEFHKKCILIWLKECKKNDEGLTCPLCRKSWPSNDFNRDVTSPLEYGPALTDSNIFVPRSHSTVMPFQHINHREITNMASSTSDLTSSNFSFNINGSKHNFNIPSNHKPLGFCFSPDVAKMLSSDMCDKREAALRQVAEQTVQIVVSAGSAYSVEDNKLNCMSGTISTDIVSSMGGFTTGLMLKEAFRVIAKLLDDTIYTLFIGALRAFREILGYLICRTESEVERMSRMISPVLCQLLRICGDSSQKKKAQMSLSALFELANGQEGGMALGREIKKTSLPVTGWQRLAKFAISNHHRFKAMHCYGRLSLLERLLDKFELTLEILRKLLEFVTYQLLLMHRSIHLLNSFDSSKLDSLETTDVDTGLSTTDIRLLSGQRLQKLAKILFINTAKLLLSKLKFQGYSHHDAYLELLKDLDKIPQPWKDKFIIKLKIPKDHLNNYENVEIDISDHNKEKKKAEGSSVTVTPGSVSKSYRISKRYSQMKPVGGAAKIGNNQLTNSVNSLKMRAGSLTQSIRSASSGSCRISPFIRITPEPAYDAVPLSESEDDISHETSSAFFSELAIHNSIYGHQFGLQESSSDERNEEEEINKTNTIFRKILQEQSNATNQKDCLDIESQPPPGLGVFSSEYRSGYEWCQGPLLGTGAFSKCYQGRDVRTGLLMAVKQISISHSCIDKNEEIIKAVKTEVNLMIQLNHPNVLPLLGAVFSPSDNTISMFVRWMPGGSVASLLTHYSAFLEPVTLAYALQTARGLSYIHSNRILHRDLKGANLLLDSSGMRLRISDFGASARLSNGRDSNASDFKGQLLGTVAFMAPEVLRGEEYGRSCDVWSFACCIIEMLTGSQPWRDRNHTNHLALMYTIASAEEPPKLPEQISADLTELLTDCLNRDPKKRPLSSKLESYRVFKHLTS 1017
BLAST of MAP3K-1 vs. TrEMBL
Match: I1ZI84 (MAP3K-1 (Fragment) OS=Schmidtea mediterranea OX=79327 PE=2 SV=1) HSP 1 Score: 670.618 bits (1729), Expect = 0.000e+0 Identity = 321/321 (100.00%), Postives = 321/321 (100.00%), Query Frame = 3
Query: 2763 MKRTNAIFRKILAEQTNSMDRKDSLDIESQPPPGLGVFSSEYRSGYEWCQGPLLGTGAFSKCYQGRDVRTGLLMAVKQISISHSSIDKNEEIIKAVKTEVNLMIQLNHPNVLPLLGAMFSPTDNIISMFVRWMPGGSVASLLNQYSAFLEPVTLAYALQTARGLSYIHSNRILHRDLKGANLLLDSSGMRLRISDFGASARLSNGRDSNASDFKGQLLGTVAFMAPEVLRGEEYGRSCDVWSFACCIIEMLTGSQPWRDRNHTNHLALMYTIASAEEPPKLPEQISADLTELLTDCLNRDPKKRPLSSKLESYRVFKHLTS 3725
MKRTNAIFRKILAEQTNSMDRKDSLDIESQPPPGLGVFSSEYRSGYEWCQGPLLGTGAFSKCYQGRDVRTGLLMAVKQISISHSSIDKNEEIIKAVKTEVNLMIQLNHPNVLPLLGAMFSPTDNIISMFVRWMPGGSVASLLNQYSAFLEPVTLAYALQTARGLSYIHSNRILHRDLKGANLLLDSSGMRLRISDFGASARLSNGRDSNASDFKGQLLGTVAFMAPEVLRGEEYGRSCDVWSFACCIIEMLTGSQPWRDRNHTNHLALMYTIASAEEPPKLPEQISADLTELLTDCLNRDPKKRPLSSKLESYRVFKHLTS
Sbjct: 15 MKRTNAIFRKILAEQTNSMDRKDSLDIESQPPPGLGVFSSEYRSGYEWCQGPLLGTGAFSKCYQGRDVRTGLLMAVKQISISHSSIDKNEEIIKAVKTEVNLMIQLNHPNVLPLLGAMFSPTDNIISMFVRWMPGGSVASLLNQYSAFLEPVTLAYALQTARGLSYIHSNRILHRDLKGANLLLDSSGMRLRISDFGASARLSNGRDSNASDFKGQLLGTVAFMAPEVLRGEEYGRSCDVWSFACCIIEMLTGSQPWRDRNHTNHLALMYTIASAEEPPKLPEQISADLTELLTDCLNRDPKKRPLSSKLESYRVFKHLTS 335
BLAST of MAP3K-1 vs. TrEMBL
Match: A0A564XX19 (Protein kinase domain-containing protein (Fragment) OS=Hymenolepis diminuta OX=6216 GN=WMSIL1_LOCUS828 PE=3 SV=1) HSP 1 Score: 317.005 bits (811), Expect = 7.069e-95 Identity = 148/279 (53.05%), Postives = 192/279 (68.82%), Query Frame = 3
Query: 2889 RSGYEWCQGPLLGTGAFSKCYQGRDVRTGLLMAVKQISISHSSIDKNEEIIKAVKTEVNLMIQLNHPNVLPLLGAMFSPTDNIISMFVRWMPGGSVASLLNQYSAFLEPVTLAYALQTARGLSYIHSNRILHRDLKGANLLLDSSGMRLRISDFGASARLSNGRDSNASDFKGQLLGTVAFMAPEVLRGEEYGRSCDVWSFACCIIEMLTGSQPWRDRNHTNHLALMYTIASAEEPPKLPEQISADLTELLTDCLNRDPKKRPLSSKLESYRVFKHLTS 3725
+ G +W GP LG GAFS CYQ RD+RTG LMAVK++ S + EE + EV +M +L HPN+L L G ++P + +FV WMPGGS+ SLLNQY AF E V+LAY LQ RG+S +H + ILHRDLKGANLL+D +G +RISDFGASARL + + S A F+GQ++GT AFMAPEVLRGE YGR+CD+WS CC++EML+G PW D TN ALM+TIAS ++PP + IS + + L C NR P++RP + +L + VF +TS
Sbjct: 1 KEGVDWLLGPFLGKGAFSLCYQARDIRTGTLMAVKRLRFVGESGSEAEEQLATAMEEVEIMRRLYHPNILRLFGIAYNPEKKHVDIFVEWMPGGSITSLLNQYGAFTESVSLAYILQVIRGISCLHKHGILHRDLKGANLLVDCTGSVVRISDFGASARLGS-QGSVAGQFQGQVIGTFAFMAPEVLRGEAYGRACDIWSVGCCLLEMLSGKPPWNDSRLTNQYALMFTIASTDQPPPYTKSISPSVRQFLDSCFNRVPEQRPTARRLLQHPVFSAITS 278
BLAST of MAP3K-1 vs. TrEMBL
Match: A0A5K3FM76 (Uncharacterized protein OS=Mesocestoides corti OX=53468 PE=4 SV=1) HSP 1 Score: 330.487 bits (846), Expect = 5.408e-94 Identity = 157/305 (51.48%), Postives = 204/305 (66.89%), Query Frame = 3
Query: 2811 NSMDRKDSLDIESQPPPGLGVFSSEYRSGYEWCQGPLLGTGAFSKCYQGRDVRTGLLMAVKQISISHSSIDKNEEIIKAVKTEVNLMIQLNHPNVLPLLGAMFSPTDNIISMFVRWMPGGSVASLLNQYSAFLEPVTLAYALQTARGLSYIHSNRILHRDLKGANLLLDSSGMRLRISDFGASARLSNGRDSNASDFKGQLLGTVAFMAPEVLRGEEYGRSCDVWSFACCIIEMLTGSQPWRDRNHTNHLALMYTIASAEEPPKLPEQISADLTELLTDCLNRDPKKRPLSSKLESYRVFKHLTS 3725
S+D K+ L E + YR G +W GP LG GAFS+CYQ RD+RTG LMAVK++ S ++ E + EV +M +L+HPNVL L G ++P + +FV WMPGGS+ SLLNQY AF EPV+LAY LQ RG+S +H + ILHRDLKGANLL+D +G +RISDFGASARL + S A F+GQ++GT AFMAPEVLRGE YGR+CD+WS CC++EML+G PW D TN ALM+TIASA++PP P+ IS + + L C NR P++RP + +L + VF + S
Sbjct: 376 QSLDAKEPLKTEYR-----------YREGVDWLLGPFLGKGAFSQCYQARDLRTGTLMAVKRLRFMGDSSAESMEQLATATEEVAIMRRLHHPNVLRLFGIAYNPEKRHVDIFVEWMPGGSITSLLNQYGAFTEPVSLAYILQVIRGISCLHKHGILHRDLKGANLLVDGTGSVVRISDFGASARLGT-QGSVAGQFQGQVIGTFAFMAPEVLRGETYGRACDIWSVGCCLLEMLSGKPPWNDSRLTNQYALMFTIASADQPPSYPKSISPPVKKFLDSCFNRIPEQRPTARRLLQHPVFSSIVS 668
BLAST of MAP3K-1 vs. TrEMBL
Match: A0A0B6ZPN5 (Protein kinase domain-containing protein (Fragment) OS=Arion vulgaris OX=1028688 GN=ORF74868 PE=3 SV=1) HSP 1 Score: 311.227 bits (796), Expect = 1.636e-90 Identity = 151/302 (50.00%), Postives = 207/302 (68.54%), Query Frame = 3
Query: 2823 RKDSLDIESQPPPGLGVFSSE------YRSGYEWCQGPLLGTGAFSKCYQGRDVRTGLLMAVKQISISHSSIDKNEEIIKAVKTEVNLMIQLNHPNVLPLLGAMFSPTDNIISMFVRWMPGGSVASLLNQYSAFLEPVTLAYALQTARGLSYIHSNRILHRDLKGANLLLDSSGMRLRISDFGASARLSNGRDSNASDFKGQLLGTVAFMAPEVLRGEEYGRSCDVWSFACCIIEMLTGSQPWRDRNHTNHLALMYTIASAEEPPKLPEQISADLTELLTDCLNRDPKKRPLSSKLESYRVF 3710
R++ + I QP G ++ Y W +GPLLGTGA+S CYQ RDVRTG++MAVKQIS +S + E++I+A+ E+++M +L+HPN++ +LGA +MFV WMPGGSVA LL +Y AF E V ++Y Q RGL+Y+H N ILHRDLKGANLL+DS+G LRI DFGASARL++ + + A +F+GQLLGT+AFMAPEVLRGE YGR+CDVWS C +IEM T PW + +NHLAL++ IAS+ + P +PE IS + +L+ CL ++ + RP + L + +F
Sbjct: 143 REEVITIRIQPDEDCGDNENDSKQPMMYLEKVNWVKGPLLGTGAYSSCYQARDVRTGVIMAVKQISFCRNSAQEQEKVIEAISEEIHMMARLSHPNIVRILGATKQGCH--FNMFVEWMPGGSVAYLLGEYGAFTENVLVSYTRQVLRGLAYLHDNHILHRDLKGANLLVDSTGQTLRIGDFGASARLAS-QATGAGEFQGQLLGTIAFMAPEVLRGESYGRACDVWSVGCVMIEMFTTKPPWNATDVSNHLALIFKIASSIDSPPIPENISPPVRDLMLRCLEQNSEDRPSAKDLLLHPLF 441
BLAST of MAP3K-1 vs. Ensembl Cavefish
Match: map3k1 (mitogen-activated protein kinase kinase kinase 1 [Source:NCBI gene;Acc:103042517]) HSP 1 Score: 312.383 bits (799), Expect = 9.772e-87 Identity = 145/285 (50.88%), Postives = 197/285 (69.12%), Query Frame = 3
Query: 2859 PGLGVFSSEYRSGYEWCQGPLLGTGAFSKCYQGRDVRTGLLMAVKQISISHSSIDKNEEIIKAVKTEVNLMIQLNHPNVLPLLGAMFSPTDNIISMFVRWMPGGSVASLLNQYSAFLEPVTLAYALQTARGLSYIHSNRILHRDLKGANLLLDSSGMRLRISDFGASARLSNGRDSNASDFKGQLLGTVAFMAPEVLRGEEYGRSCDVWSFACCIIEMLTGSQPWRDRNHTNHLALMYTIASAEEPPKLPEQISADLTELLTDCLNRDPKKRPLSSKLESYRVFK 3713
PG YR G EW +G +G GAFS CYQ +DV TG LMAVKQ++ ++ + EE+++A++ E+ +M LNHPN++ +LGA N ++FV WM GGSV+ LLN+Y AF E V + Y Q RGL+Y+H N+I+HRD+KGANLL+DS+G RLRI+DFGA+ARL++ + + A +F+GQLLGT+AFMAPEVLRG++YGRSCDVWS C IIEM PW H+NHLAL++ IASA P +P Q+S L ++ CL P RP S +L + +F+
Sbjct: 1235 PGHTKAKQPYREGAEWLKGQQIGLGAFSSCYQAQDVGTGTLMAVKQVTYVRNTSSEQEEVVEALREEIRMMSHLNHPNIIRMLGATCE--KNNYNLFVEWMAGGSVSHLLNKYGAFKEGVIINYTEQLLRGLAYLHENQIIHRDIKGANLLIDSTGQRLRIADFGAAARLAS-KGTGAGEFQGQLLGTIAFMAPEVLRGQQYGRSCDVWSVGCAIIEMSCAKPPWNAEKHSNHLALIFKIASATTAPTIPPQLSPGLRDVTLRCLELQPADRPPSRELLKHPIFR 1516 HSP 2 Score: 100.908 bits (250), Expect = 7.180e-21 Identity = 73/245 (29.80%), Postives = 109/245 (44.49%), Query Frame = 3
Query: 387 YRQSNIQEKLKIISQQNFCILPQCSPTSFTVCAGS-SSRYVVNIGPQXXXXXXXXXXXXNQHSFPCVHLLFIMCKVLQVHERDPLLLEKHLKNIEVDELFKRFNKRIKEKLNNPYRPNDKNCKNINHEEEHEGNTSRFGRDATSFGLQYKSVMKNMMAHVLEKCRNKNKHDC--DEPRPNESLDEITCSICLQEMNIAQLLIFCH-NCSNEFHKKCILIWLKECKKNNEELTCPLCRKSWPSDDI 1109
Y ++ + + +L Q P SF + S ++Y V IGPQTC C + +F C+H+LF+M +V Q+ DPLL K LKN EV+ LF++++ R ++ P R NT + ++ S M N + + DE +E C ICL +M + L C C N+ H C+ IW +EC++N+E L CPLCR W S D
Sbjct: 313 YSPEETNRRVNKVMRARLYLLQQIGPNSFLIGGDSPDNKYRVFIGPQTCSC--------GRGAF-CIHVLFVMLRVFQLESSDPLLWRKTLKNFEVESLFQKYHNRRSSRIKAPSR-----------------NTIQ----------KFVSRMSNSHTNCTSSSSPSSNESSMKDE-------EEQMCPICLLDMLDEESLTVCEEGCRNKLHHHCMSIWAEECRRNHEPLICPLCRAKWKSHDF 514 HSP 3 Score: 68.9366 bits (167), Expect = 4.057e-11 Identity = 43/134 (32.09%), Postives = 76/134 (56.72%), Query Frame = 3
Query: 1566 VIARLLDDTSYTLFVGALRAFREILGYLICRTESEVERMSRMISPVLCQLLRICGDNSQKKKAQMCLSALFELANGQEGGMALGREI-KKSSLPVTGWQRLAKFAIANH---HRFKAVHCYGRLSLLERLLDKF 1955
V++ + D Y ++V AL+ R +L Y C + SE R+ +++ PV+ +L C D + + +Q+ +S L EL GQ G +A+GREI K S+ + G + + + + ++A+ GRL L++RLL +F
Sbjct: 652 VLSMVCADPVYKVYVAALKTLRAMLVYTPCHSLSERSRLQQLLRPVVETILVKCAD-ANSRTSQLSVSTLLELCKGQLGELAVGREILKAGSIGIGGVDYVLNCILGSQTESNNWQAL--LGRLCLIDRLLLEF 782
BLAST of MAP3K-1 vs. Ensembl Cavefish
Match: map3k22 (mitogen-activated protein kinase kinase kinase 3-like [Source:NCBI gene;Acc:103044968]) HSP 1 Score: 183.726 bits (465), Expect = 3.357e-48 Identity = 103/266 (38.72%), Postives = 147/266 (55.26%), Query Frame = 3
Query: 2904 WCQGPLLGTGAFSKCYQGRDVRTGLLMAVKQISISHSSIDKNEEIIKAVKTEVNLMIQLNHPNVLPLLGAMFSPTDNIISMFVRWMPGGSVASLLNQYSAFLEPVTLAYALQTARGLSYIHSNRILHRDLKGANLLLDSSGMRLRISDFGASARLSNGRDSNASDFKGQLLGTVAFMAPEVLRGEEYGRSCDVWSFACCIIEMLTGSQPWRDRNHTNHLALMYTIASAEEPPKLPEQISADLTELLTDCLNRDPKKRPLSSKLESY 3701
W QG LLG GAF + Y D TG +AVKQ+ + ++E+ A++ E+ L+ L H ++ G + P +S+FV +MPGGS+ L Y A E VT Y Q +G+ Y+HSN I+HRD+KGAN+L DSSG +++ DFGAS R+ S + GT +M+PEV+ GE YGR DVWS AC ++EMLT PW + +A ++ IA+ P LPE +S + L + K RP + L S+
Sbjct: 354 WRQGKLLGRGAFGEVYLCYDADTGRELAVKQVPFDPECHETSKEV-NALECEIQLLKNLRHERIVQYYGCLRDPEQRKLSIFVEFMPGGSIKDQLKAYGALTEKVTRRYTRQILQGVFYLHSNMIVHRDIKGANILRDSSG-NVKLGDFGASKRIQTICMSGTG--IKTVTGTPYWMSPEVINGEGYGRKADVWSVACTVVEMLTQKPPWAE---YEAMAAIFKIATQPTKPNLPEGVSDACRDFLRQVFVEE-KWRPTAEGLLSH 611
BLAST of MAP3K-1 vs. Ensembl Cavefish
Match: map3k22 (mitogen-activated protein kinase kinase kinase 3-like [Source:NCBI gene;Acc:103044968]) HSP 1 Score: 183.726 bits (465), Expect = 3.749e-48 Identity = 103/266 (38.72%), Postives = 147/266 (55.26%), Query Frame = 3
Query: 2904 WCQGPLLGTGAFSKCYQGRDVRTGLLMAVKQISISHSSIDKNEEIIKAVKTEVNLMIQLNHPNVLPLLGAMFSPTDNIISMFVRWMPGGSVASLLNQYSAFLEPVTLAYALQTARGLSYIHSNRILHRDLKGANLLLDSSGMRLRISDFGASARLSNGRDSNASDFKGQLLGTVAFMAPEVLRGEEYGRSCDVWSFACCIIEMLTGSQPWRDRNHTNHLALMYTIASAEEPPKLPEQISADLTELLTDCLNRDPKKRPLSSKLESY 3701
W QG LLG GAF + Y D TG +AVKQ+ + ++E+ A++ E+ L+ L H ++ G + P +S+FV +MPGGS+ L Y A E VT Y Q +G+ Y+HSN I+HRD+KGAN+L DSSG +++ DFGAS R+ S + GT +M+PEV+ GE YGR DVWS AC ++EMLT PW + +A ++ IA+ P LPE +S + L + K RP + L S+
Sbjct: 357 WRQGKLLGRGAFGEVYLCYDADTGRELAVKQVPFDPECHETSKEV-NALECEIQLLKNLRHERIVQYYGCLRDPEQRKLSIFVEFMPGGSIKDQLKAYGALTEKVTRRYTRQILQGVFYLHSNMIVHRDIKGANILRDSSG-NVKLGDFGASKRIQTICMSGTG--IKTVTGTPYWMSPEVINGEGYGRKADVWSVACTVVEMLTQKPPWAE---YEAMAAIFKIATQPTKPNLPEGVSDACRDFLRQVFVEE-KWRPTAEGLLSH 614
BLAST of MAP3K-1 vs. Ensembl Cavefish
Match: map3k19 (mitogen-activated protein kinase kinase kinase 19 [Source:ZFIN;Acc:ZDB-GENE-081104-140]) HSP 1 Score: 170.629 bits (431), Expect = 7.505e-47 Identity = 96/265 (36.23%), Postives = 152/265 (57.36%), Query Frame = 3
Query: 2904 WCQGPLLGTGAFSKCYQGRDVRTGLLMAVKQISISHSSIDKNEEIIKAVKTEVNLMIQLNHPNVLPLLGAMFSPTDNIISMFVRWMPGGSVASLLNQYSAFLEPVTLAYALQTARGLSYIHSNRILHRDLKGANLLLDSSGMRLRISDFGASARLSNGRDSNA-SDFKGQLLGTVAFMAPEVLRGEEYGRSCDVWSFACCIIEMLTGSQPWRDRNHTNHLALMYTIASAEE-PPKLPEQISADLTELLTDCLNRDPKKRPLSSKL 3692
W +G +LG GA+ Y G G L+AVKQ+ + S+ + E+ ++ EV+L+ L HPN++ LG TDN+IS+F+ ++PGGS++S+LN++ E V Y Q G++Y+H NR++HRDLKG NL+L +G+ +++ DFG + RL+ S SD + GT +MAPEV+ +G+ DVWS C + EM TG P H +A ++ I + + P LP+ S + + CL + K+RP ++ L
Sbjct: 16 WAKGEVLGRGAYGTVYCGL-TSQGQLIAVKQVLLDVSTSETAEKEYSRLEREVDLLKNLEHPNIVGFLGTAL--TDNVISIFMEYVPGGSISSVLNRFGPLPEKVFALYTRQVLEGVAYLHENRVIHRDLKGNNLMLMPTGV-VKLIDFGCARRLNRLTHSGGNSDLLKSVHGTPYWMAPEVINETGHGKKSDVWSIGCTVFEMATGKPPLA---HMGKMAALFYIGARKGLMPPLPDDFSEEAKSFVKACL-INQKQRPSAADL 272
BLAST of MAP3K-1 vs. Ensembl Cavefish
Match: map3k3 (mitogen-activated protein kinase kinase kinase 3 [Source:NCBI gene;Acc:103034596]) HSP 1 Score: 177.178 bits (448), Expect = 6.663e-46 Identity = 99/266 (37.22%), Postives = 148/266 (55.64%), Query Frame = 3
Query: 2904 WCQGPLLGTGAFSKCYQGRDVRTGLLMAVKQISISHSSIDKNEEIIKAVKTEVNLMIQLNHPNVLPLLGAMFSPTDNIISMFVRWMPGGSVASLLNQYSAFLEPVTLAYALQTARGLSYIHSNRILHRDLKGANLLLDSSGMRLRISDFGASARLSNGRDSNASDFKGQLLGTVAFMAPEVLRGEEYGRSCDVWSFACCIIEMLTGSQPWRDRNHTNHLALMYTIASAEEPPKLPEQISADLTELLTDCLNR---DPKKRPLSSKL 3692
W +G LLG GAF + Y DV TG +A KQ+ +S + ++E+ ++ E+ L+ L+H ++ G + + +++F+ +MPGGSV L Y A E VT Y Q G+SY+HSN I+HRD+KGAN+L DS+G +++ DFGAS RL +S + GT +M+PEV+ G+ YGR DVWS C ++EMLT PW + +A ++ IA+ P LP S E D + R + K RP + +L
Sbjct: 356 WRRGKLLGQGAFGRVYLCYDVDTGRELAAKQVQFDPASPETSKEV-STLECEIQLLKNLHHERIVQYYGCLRDHNEKTLTIFMEYMPGGSVKDQLKAYGALTENVTRKYTRQILEGMSYLHSNMIVHRDIKGANILRDSAG-NVKLGDFGASKRLQT--ICMSSTGVRSVTGTPYWMSPEVISGDGYGRKADVWSLGCTVVEMLTEKPPWAE---YEAMAAIFKIATQPTNPILPSHTS----EQTRDFIRRIFVEAKHRPSAEEL 610
BLAST of MAP3K-1 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000006402.1 (pep scaffold:Pmarinus_7.0:GL481397:10373:21355:-1 gene:ENSPMAG00000005783.1 transcript:ENSPMAT00000006402.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 280.411 bits (716), Expect = 1.012e-85 Identity = 131/280 (46.79%), Postives = 193/280 (68.93%), Query Frame = 3
Query: 2886 YRSGYEWCQGPLLGTGAFSKCYQGRDVRTGLLMAVKQISISHSSIDKNEEIIKAVKTEVNLMIQLNHPNVLPLLGAMFSPTDNIISMFVRWMPGGSVASLLNQYSAFLEPVTLAYALQTARGLSYIHSNR----ILHRDLKGANLLLDSSGMRLRISDFGASARLSNGRDSNASDFKGQLLGTVAFMAPEVLRGEEYGRSCDVWSFACCIIEMLTGSQPWRDRNHTNHLALMYTIASAEEPPKLPEQISADLTELLTDCLNRDPKKRPLSSKLESYRVFK 3713
Y+ G EW +G +G GAFS C+Q +D+ TG LMAVKQ++ ++ + +E+++ ++ E+ +M +L+HPN++ +LGA ++ ++F+ WM GGSVA+LLN+Y F E V ++Y Q RGL+Y+HSN+ ++HRD+KGANLL+DS G RLRI+DFGA+ARL++ + + A +F+GQLLGT+AFMAPEVLRG +YGRSCD+WS C IIEM PW H+NHLAL++ IAS P +P + L ++ CL P RP++ L + VF+
Sbjct: 18 YQEGAEWLRGQQIGLGAFSSCFQAQDIGTGTLMAVKQVTYVRNTASEQDEVVQTLREEIRMMSRLDHPNIIRMLGATCEKSN--YNLFIEWMAGGSVANLLNKYGPFHERVVISYVEQLLRGLAYLHSNQHSNQLIHRDIKGANLLVDSMGQRLRIADFGAAARLAS-KGTGAGEFQGQLLGTIAFMAPEVLRGLQYGRSCDIWSVGCVIIEMSCAKPPWNAEKHSNHLALIFKIASTTTAPTVPPTLCPGLRDVALRCLELQPSDRPVARDLLKHPVFR 294
BLAST of MAP3K-1 vs. Ensembl Sea Lamprey
Match: map3k2 (mitogen-activated protein kinase kinase kinase 2 [Source:ZFIN;Acc:ZDB-GENE-120215-96]) HSP 1 Score: 181.415 bits (459), Expect = 4.971e-48 Identity = 94/251 (37.45%), Postives = 141/251 (56.18%), Query Frame = 3
Query: 2889 RSGYEWCQGPLLGTGAFSKCYQGRDVRTGLLMAVKQISISHSSIDKNEEIIKAVKTEVNLMIQLNHPNVLPLLGAMFSPTDNIISMFVRWMPGGSVASLLNQYSAFLEPVTLAYALQTARGLSYIHSNRILHRDLKGANLLLDSSGMRLRISDFGASARLSNGRDSNASDFKGQLLGTVAFMAPEVLRGEEYGRSCDVWSFACCIIEMLTGSQPWRDRNHTNHLALMYTIASAEEPPKLPEQISADLTELL 3641
R+ W +G LLG GAF + Y D TG +AVKQ+ S++ ++E+ A++ E+ L+ L H ++ G + P +S+F+ +MPGGS+ L Y A E VT Y Q G+S++H N I+HRD+KGAN+L DS+G +++ DFGAS RL + + GT +M+PEV+ GE YGR D+WS C ++EMLT PW + +A ++ IA+ P+LP S +LL
Sbjct: 354 RAPTNWQRGKLLGQGAFGRVYLCYDADTGRELAVKQVQFDPGSVETSKEV-NALECEIQLLKNLQHERIVQYFGCLRDPQQKTLSIFMEYMPGGSIKDQLRAYGALTENVTRKYTRQILEGVSFLHGNMIVHRDIKGANILRDSTG-NVKLGDFGASKRLQTICSQGTA--MRSVTGTPYWMSPEVINGEGYGRKADIWSVGCTVVEMLTEKPPWAE---FEAMAAIFKIATQPTDPRLPLHASEHARDLL 597
BLAST of MAP3K-1 vs. Ensembl Sea Lamprey
Match: map3k19 (mitogen-activated protein kinase kinase kinase 19 [Source:ZFIN;Acc:ZDB-GENE-081104-140]) HSP 1 Score: 147.517 bits (371), Expect = 1.806e-39 Identity = 89/273 (32.60%), Postives = 141/273 (51.65%), Query Frame = 3
Query: 2904 WCQGPLLGTGAFSKCYQGRDVRTGLLMAVKQISI-------SHSSIDKNEEIIKAVKTEVNLMIQLNHPNVLPLLGAMFSPTDNIISMFVRWMPGGSVASLLNQYSAFLEPVTLAYALQTARGLSYIHSNRILHRDLKGANLLLDSSGMRLRISDFGASARLSNGRDSNASDFKGQLLGTVAFMAPEVLRGEEYGRSCDVWSFACCIIEMLTGSQPWRDRNHTNHLALMYTIASAEEPPKLPEQISADLTELLTDCLNRDPKKRPLSSKLESY 3701
W +G LG GAF + G G L+AVK++ + + K E+ K ++ EV L+ L+HPNV+ LG N S+F+ ++PGG+VA + + E V +Y Q RGL+Y+H + ++H D+KG+N ++ +G+ +++ DFG + R++ + + + GT +MAPEV+ G Y R DVWS C + EM G P+ D AL++ P LP+ S + E + C RD KRP S +L S+
Sbjct: 15 WIKGNRLGKGAFGTVFLGL-TNQGKLIAVKELELRDAQSANGNQGGQKQSELQK-LQDEVELLTTLHHPNVVEYLGTEME--GNRFSIFMEFVPGGTVAETVRGFGPLGESVCRSYIAQMTRGLAYLHGHGVMHGDVKGSNAVITPAGV-VKLIDFGCAQRVALALSCHENGGLHSVHGTAYWMAPEVINGTGYARRADVWSLGCTLHEMAVGRPPFADM--APMAALLHIGIRNGIMPGLPQAFSKEAQEFVEQCFIRDKLKRPSSQELLSH 280
BLAST of MAP3K-1 vs. Ensembl Sea Lamprey
Match: slka (STE20-like kinase a [Source:ZFIN;Acc:ZDB-GENE-050411-66]) HSP 1 Score: 135.576 bits (340), Expect = 2.605e-32 Identity = 88/260 (33.85%), Postives = 137/260 (52.69%), Query Frame = 3
Query: 2922 LGTGAFSKCYQGRDVRTGLLMAVKQISISHSSIDKNEEIIKAVKTEVNLMIQLNHPNVLPLLGAMFSPTDNIISMFVRWMPGGSV-ASLLNQYSAFLEPVTLAYALQTARGLSYIHSNRILHRDLKGANLLLDSSGMRLRISDFGASARLSNGRDSNASDFKGQLLGTVAFMAPEVLRGEE-----YGRSCDVWSFACCIIEMLTGSQPWRDRNHT-NHLALMYTIASAEEPPKL--PEQISADLTELLTDCLNRDPKKR 3674
LG GAF K Y+ ++ +G+L A K I K+EE ++ E+ ++ +HPN++ LL A + +N + +F+ + PGG+V A +L EP Q L+Y+H++RI+HRDLK N+LL G ++++DFG SA+ N R D +GT +MAPEV+ E Y D+WS +IE+ P NH N + +M IA +PP L P + SA+ T+ L CL+++P+ R
Sbjct: 39 LGDGAFGKVYKAQNKESGVLAAAKVIET------KSEEELEDYMVEIEILALCDHPNIVGLLNAFY--YENKLWIFIEFCPGGAVDAIMLELERGLAEPQIRVVCKQMLEALNYLHTHRIIHRDLKAGNILLTFEG-DVKLADFGVSAK--NTRTLQRRD---SFIGTPYWMAPEVVMCETMKDAPYDYKADIWSLGITLIELAQMEPP----NHELNPMRVMLKIAK-NDPPSLSFPSKWSAEFTDFLKKCLDKNPETR 279
BLAST of MAP3K-1 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000006100.1 (pep scaffold:Pmarinus_7.0:GL478927:1672:12797:-1 gene:ENSPMAG00000005510.1 transcript:ENSPMAT00000006100.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 117.087 bits (292), Expect = 5.390e-29 Identity = 90/307 (29.32%), Postives = 151/307 (49.19%), Query Frame = 3
Query: 2832 SLDIESQPPPGLGVFSSEYRSGYEWCQGPLLGTGAFSKCYQGRDVRTGLLMAVKQISISHSSIDKNEEIIKAVKTEVNLMIQLNHPNVLPLLGAMFSPTDNIISMFVRWMPGGSVASLLNQYSA---FLEPVTLAYALQTARGLSYIHSNR---ILHRDLKGANLLLDSSGMRLRISDFGASARLSNGRDSNASDFKGQLLGTVAFMAPEVLRGEEYGRSCDVWSFACCIIEMLTGSQPWRDRNHTNHLALMYTIASAEEPPKLPEQISADLTELLTDCLNRDPKKRPLSSKLESYRVFKHLTS*MF 3734
S D+E+ PP F E S E ++G GAF + + G+ +A+KQI ++E KA E+ + ++NHPN++ L GA +P + + + + GGS+ ++L+ + + + LQ A+G++Y+H + ++HRDLK NLLL S G L+I DFG + + +N G+ A+MAPEV G Y CDV+S+ + E++T +P+ D +M+ + + PP L + + + L+T C +++P RP S E R+ HL F
Sbjct: 7 SGDMEATPPG----FVEEIDSD-EIIVEEVVGRGAFGVVCKAK--WRGMDVAIKQI--------ESESERKAFIVELRQLSRVNHPNIVRLYGACLNP----VCLVMEYAEGGSLYNVLHGAEPLPYYTAAHAMRWCLQCAQGVAYLHCMKPKALIHRDLKPPNLLLISGGTILKICDFGTACDIQTHMTNNK--------GSAAWMAPEVFEGSNYSEKCDVFSWGIILWEVITRRKPF-DEIGGPAFRIMWAVHNGTRPP-LIKNLPKPIEGLMTRCWDKEPALRP--SMEEIVRIMIHLMKVQF 282
BLAST of MAP3K-1 vs. Ensembl Yeast
Match: BCK1 (MAPKKK acting in the protein kinase C signaling pathway; the kinase C signaling pathway controls cell integrity; upon activation by Pkc1p phosphorylates downstream kinases Mkk1p and Mkk2p; MAPKKK is an acronym for mitogen-activated protein (MAP) kinase kinase kinase [Source:SGD;Acc:S000003631]) HSP 1 Score: 177.948 bits (450), Expect = 2.383e-45 Identity = 106/281 (37.72%), Postives = 163/281 (58.01%), Query Frame = 3
Query: 2883 EYRSGYEWCQGPLLGTGAFSKCYQGRDVRTGLLMAVKQISISHSSIDKNEEI---IKAVKTEVNLMIQLNHPNVLPLLGAMFSPTDNIISMFVRWMPGGSVASLLNQYSAFLEPVTLAYALQTARGLSYIHSNRILHRDLKGANLLLDSSGMRLRISDFGASARLSNGRDSNASDFKGQLLGTVAFMAPEVLRGEE-YGRSCDVWSFACCIIEMLTGSQPWRDRNHTNHLALMYTIASAEEPPKLPEQ----ISADLTELLTDCLNRDPKKRPLSSKLESY 3701
EY+ + W +G ++G G+F Y +V TG +MAVKQ+ + S +NE I ++A+++EV+ + L+H N++ LG F +NI S+F+ ++ GGSV SL+ Y F EP+ Q +GL+Y+HS ILHRD+K NLLLD G+ +ISDFG S R S SN SD + GTV +MAPE++ ++ Y D+WS C ++EM G +PW ++ +A M+ I ++ P +PE IS L C +P+KRP +++L S+
Sbjct: 1169 EYKE-FAWMKGEMIGKGSFGAVYLCLNVTTGEMMAVKQVEVPKYS-SQNEAILSTVEALRSEVSTLKDLDHLNIVQYLG--FENKNNIYSLFLEYVAGGSVGSLIRMYGRFDEPLIKHLTTQVLKGLAYLHSKGILHRDMKADNLLLDQDGI-CKISDFGIS-RKSKDIYSN-SDM--TMRGTVFWMAPEMVDTKQGYSAKVDIWSLGCIVLEMFAGKRPW---SNLEVVAAMFKIGKSKSAPPIPEDTLPLISQIGRNFLDACFEINPEKRPTANELLSH 1437
BLAST of MAP3K-1 vs. Ensembl Yeast
Match: STE11 (Signal transducing MEK kinase; involved in pheromone response and pseudohyphal/invasive growth pathways where it phosphorylates Ste7p, and the high osmolarity response pathway, via phosphorylation of Pbs2p; regulated by Ste20p and Ste50p; protein abundance increases in response to DNA replication stress [Source:SGD;Acc:S000004354]) HSP 1 Score: 151.369 bits (381), Expect = 5.722e-38 Identity = 89/298 (29.87%), Postives = 153/298 (51.34%), Query Frame = 3
Query: 2904 WCQGPLLGTGAFSKCYQGRDVRTGLLMAVKQISISHSSI----DKNEE----------------------------------IIKAVKTEVNLMIQLNHPNVLPLLGAMFSPTDNIISMFVRWMPGGSVASLLNQYSAFLEPVTLAYALQTARGLSYIHSNRILHRDLKGANLLLDSSGMRLRISDFGASARLS--NGRDSNASDFKGQLLGTVAFMAPEVLRGEEYGRSCDVWSFACCIIEMLTGSQPWRDRNHTNHLALMYTIASAEEPPKLPEQISADLTELLTDCLNRDPKKRP 3677
W +G +G+G+F Y G + TG LMAVKQ+ I +++I D N++ ++ A++ E+NL+ +L+H N++ GA S +++F+ ++PGGSV+S+LN Y F E + + Q G++Y+H I+HRD+KGAN+L+D G ++I+DFG S +LS N + + + L G+V +M+PEV++ D+WS C +IEM TG P+ D + + ++ I + P++P +++ L D + RP
Sbjct: 415 WLKGACIGSGSFGSVYLGMNAHTGELMAVKQVEIKNNNIGVPTDNNKQANSDENNEQEEQQEKIEDVGAVSHPKTNQNIHRKMVDALQHEMNLLKELHHENIVTYYGA--SQEGGNLNIFLEYVPGGSVSSMLNNYGPFEESLITNFTRQILIGVAYLHKKNIIHRDIKGANILIDIKGC-VKITDFGISKKLSPLNKKQNK----RASLQGSVFWMSPEVVKQTATTAKADIWSTGCVVIEMFTGKHPFPD---FSQMQAIFKIGT-NTTPEIPSWATSEGKNFLRKAFELDYQYRP 701
BLAST of MAP3K-1 vs. Ensembl Yeast
Match: SSK22 (MAP kinase kinase kinase of HOG1 mitogen-activated signaling pathway; functionally redundant with Ssk2p; interacts with and is activated by Ssk1p; phosphorylates Pbs2p; SSK22 has a paralog, SSK2, that arose from the whole genome duplication [Source:SGD;Acc:S000000669]) HSP 1 Score: 145.591 bits (366), Expect = 1.869e-35 Identity = 89/279 (31.90%), Postives = 151/279 (54.12%), Query Frame = 3
Query: 2904 WCQGPLLGTGAFSKCYQGRDVRTGLLMAVKQISISHSSIDKNEEIIKAVKTEVNLMIQLNHPNVLPLLGAMFSPTDNIISMFVRWMPGGSVASLLNQYSAFLEPVTLAYALQTARGLSYIHSNRILHRDLKGANLLLDSSGMRLRISDFGAS-----ARLSNGRDSNASDFK------GQLLGTVAFMAPEVLRGEEY-GR--SCDVWSFACCIIEMLTGSQPWRDRNHTNHLALMYTIASAEEPPKLP--EQISADLTELLTDCLNRDPKKRPLSSKL 3692
W + +G G F + Y ++ G ++AVK+I I ++ K +I +K E+ ++ LNHPN++ G + +++F+ + GGS+ASLL+ E VT Y + GL+Y+H + ++HRD+K N+LLD +G+ ++ DFG + +R R++ DF +++GT +MAPE + G G+ + DVW+ C ++EM TG +PW N N A+MY +A A P+LP ++++A L CL +DP R + +L
Sbjct: 1034 WQKRSFIGGGTFGQVYSAINLENGEILAVKEIKIHDTTTMK--KIFPLIKEEMTVLEMLNHPNIVQYYGV--EVHRDKVNIFMEYCEGGSLASLLDHGRIEDEMVTQVYTFELLEGLAYLHQSGVVHRDIKPENILLDFNGI-IKYVDFGTARTVVGSRTRTVRNAAVQDFGVETKSLNEMMGTPMYMAPETISGSAVKGKLGADDVWALGCVVLEMATGRRPW--SNLDNEWAIMYHVA-AGRIPQLPNRDEMTAAGRAFLERCLVQDPTMRATAVEL 1304
BLAST of MAP3K-1 vs. Ensembl Yeast
Match: SSK2 (MAP kinase kinase kinase of HOG1 mitogen-activated signaling pathway; interacts with Ssk1p, leading to autophosphorylation and activation of Ssk2p which phosphorylates Pbs2p; also mediates actin cytoskeleton recovery from osmotic stress; a HOG-independent function of Ssk2p mediates the calcium-sensitive phenotype of the ptp2 msg5 double disruptant; SSK2 has a paralog, SSK22, that arose from the whole genome duplication [Source:SGD;Acc:S000005314]) HSP 1 Score: 144.821 bits (364), Expect = 3.198e-35 Identity = 93/295 (31.53%), Postives = 156/295 (52.88%), Query Frame = 3
Query: 2904 WCQGPLLGTGAFSKCYQGRDVRTGLLMAVKQISISHSSIDKNEEIIKAVKTEVNLMIQLNHPNVLPLLGAMFSPTDNIISMFVRWMPGGSVASLLNQYSAFLEPVTLAYALQTARGLSYIHSNRILHRDLKGANLLLDSSGMRLRISDFGASARLSNGRD------------------SNASDFKG---------QLLGTVAFMAPEVLRGEEY-GR--SCDVWSFACCIIEMLTGSQPWRDRNHTNHLALMYTIASAEEPPKLP--EQISADLTELLTDCLNRDPKKRPLSSKL 3692
W + +G G F + Y D+ G ++AVK+I+I S ++I +K E++++ LNHPN++ G + +++F+ + GGS+A+LL E VT Y LQ GL+Y+H + I+HRD+K N+LLD +G+ ++ DFGA+ +++N ++ SD K ++GT +MAPE + G G+ + DVWS C ++EM+TG +PW N N A+MY +A A P+ P +++S+ + L CL ++P KR + +L
Sbjct: 1266 WQKRNFIGGGTFGRVYSAVDLDNGEILAVKEINIQDSK--SMQKIFPLIKEEMSVLEILNHPNIVSYYGVEVHR--DKVNIFMEYCEGGSLAALLEHGRIEDEMVTQVYTLQLLEGLAYLHESGIVHRDVKPENILLDFNGV-IKYVDFGAAKKIANNGTRLASMNKIENADGEHEDVTHVSDSKAVKNNENALLDMMGTPMYMAPESITGSTTKGKLGADDVWSLGCVVLEMITGRRPW--ANLDNEWAIMYHVA-AGHTPQFPTKDEVSSAGMKFLERCLIQNPSKRASAVEL 1552
BLAST of MAP3K-1 vs. Ensembl Yeast
Match: CDC5 (Polo-like kinase; controls targeting and activation of Rho1p at cell division site via Rho1p guanine nucleotide exchange factors; regulates Spc72p; also functions in adaptation to DNA damage during meiosis; regulates the shape of the nucleus and expansion of the nuclear envelope during mitosis; similar to Xenopus Plx1 and S. pombe Plo1p; human homologs PLK1, PLK3 can each complement yeast cdc5 thermosensitive mutants [Source:SGD;Acc:S000004603]) HSP 1 Score: 127.102 bits (318), Expect = 2.708e-30 Identity = 83/275 (30.18%), Postives = 143/275 (52.00%), Query Frame = 3
Query: 2895 GYEWCQGPLLGTGAFSKCYQGRDVRTGLLMAVKQISISHSSIDKNEEIIKAVKTEVNLMIQLNHPNVLPLLGAMFSPTDNIISMFVRWMPGGSVASLLNQYSAFLEPVTLAYALQTARGLSYIHSNRILHRDLKGANLLLDSSGMRLRISDFGASARLSNGRDSNASDFKGQLLGTVAFMAPEVLRGEEYGRS--CDVWSFACCIIEMLTGSQPWRDRNHTNHLALMYTIASAEEPPKLPEQISADLTELLTDCLNRDPKKRPLSSKLESYRVFK 3713
G ++ +G LG G F++C+Q +D +G + A K +++ +SI K+E+ K + +E+ + ++HPN++ + D+ + + + P GS+ LL + EP + Q + Y+HS R++HRDLK N+ DS+ L+I DFG +A L +N S+ K + GT ++APEVL G+ G S D+WS + +L G P++ R+ N + P P IS + L+ D L+ DP +RP +++ Y F+
Sbjct: 79 GKDYHRGHFLGEGGFARCFQIKD-DSGEIFAAK--TVAKASI-KSEKTRKKLLSEIQIHKSMSHPNIVQFIDCF--EDDSNVYILLEICPNGSLMELLKRRKVLTEPEVRFFTTQICGAIKYMHSRRVIHRDLKLGNIFFDSN-YNLKIGDFGLAAVL-----ANESERKYTICGTPNYIAPEVLMGKHSGHSFEVDIWSLGVMLYALLIGKPPFQARD-VNTIYERIKCRDFSFPRDKP--ISDEGKILIRDILSLDPIERPSLTEIMDYVWFR 338
BLAST of MAP3K-1 vs. Ensembl Nematostella
Match: EDO36150 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SJF2]) HSP 1 Score: 276.559 bits (706), Expect = 3.788e-78 Identity = 127/275 (46.18%), Postives = 187/275 (68.00%), Query Frame = 3
Query: 2886 YRSGYEWCQGPLLGTGAFSKCYQGRDVRTGLLMAVKQISISHSSIDKNEEIIKAVKTEVNLMIQLNHPNVLPLLGAMFSPTDNIISMFVRWMPGGSVASLLNQYSAFLEPVTLAYALQTARGLSYIHSNRILHRDLKGANLLLDSSGMRLRISDFGASARLSNGRDSNASDFKGQLLGTVAFMAPEVLRGEEYGRSCDVWSFACCIIEMLTGSQPWRDRNHTNHLALMYTIASAEEPPKLPEQISADLTELLTDCLNRDPKKRPLSSKLESYRVF 3710
Y W +G LLGTGAFS CY RDV TG LMAVKQ+S +S + +++ + + E+ ++ +L HP+++ LGA + ++F+ WM GGS++ LL++Y F E + + Y Q +G+SY+H N+++HRD+KGAN+L+DS+G +RI+DFGA+ARL+ + + A +F+GQLLGT+AFMAPEVLRGE YGRSCDVWS C +IEM TG PW H+NHLAL++ IA A PP +PE ++ + +++ CL P+ RP + L + +F
Sbjct: 571 YLENVHWKKGELLGTGAFSSCYGARDVMTGSLMAVKQVSFCRNSKSEQDKVCQTIMDEIAILARLKHPHLIKCLGA--TRHTGHFNIFLEWMAGGSISMLLSKYGPFEEAILIRYLRQILQGVSYLHENQVVHRDIKGANILVDSTGQDIRIADFGAAARLAT-QITGAGEFQGQLLGTIAFMAPEVLRGESYGRSCDVWSVGCVLIEMATGKPPWNAHEHSNHLALIFKIACAIGPPDIPEHLNPGVRDVVLRCLESKPEDRPAAVDLLQHPLF 842 HSP 2 Score: 80.8777 bits (198), Expect = 2.162e-15 Identity = 79/351 (22.51%), Postives = 136/351 (38.75%), Query Frame = 3
Query: 927 DEITCSICLQEMNIAQLLIFC-HNCSNEFHKKCILIWLKECKKNNEELTCPLCRKSWPSDDISRDIVSPLEYGPSVADSNFFVPRSHSTATSFQH-INHREITNIAXXXXXXXXXXXXXXINGSKHGFSVSSNH----KPIGYCFSALVAEMLSSDMSDKREAGLRQVAEQTVQIVVSAGSAYSVEDNKVNCMSDTISTDIVSSMGGFTTGLMLKEAFRVIARLLDDTSYTLFVGALRAFREILGYLICRTESEVERMSRMISPVLCQLLRICGDNSQKKKAQMCLSALFELANGQEGGMALGREIKKSSL-PVTGWQRLAKFAIANHHRFKAVHCY-GRLSLLERLLDKF 1955
DE C ICL EM + L C C+N H+ C+ IW EC+ E L CPLCR+ + P E S++D + P+ A + + E+ + H + + +P F + L S + RE LR+++ YS N+ + ++D + + S+ G D Y ++V ALR R +L + + E + + PV+ +L C D +++ A + + L E + G +ALGR ++ + P+ G + + H + + GRL L +LLD++
Sbjct: 22 DEEVCPICLLEMVEGESLTCCTGGCNNTLHQHCMEIWAAECRLRKERLNCPLCRR-----------ILPPEAAKSLSDRSPTGPKFLPCAPDVPNPLEPGEVITL-------------------PHSNPIPTGQVDLARPWVQAFGEELVSCLFSREWNIREIALRRLSRDI----------YSYLRNEASNLTDLTAVEASCSLLTMMCG---------------DPVYRVYVAALRTLRVMLAHTNYTSRDEKMLIQSYLHPVVEAILAKCSDGNRRISA-LSMKVLLEFCKDESGDLALGRMLRDHRIQPMGGLGFMLACILTTAHEYATWPWWLGRLYFLRKLLDEY 316
BLAST of MAP3K-1 vs. Ensembl Nematostella
Match: EDO27976 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7T7S3]) HSP 1 Score: 203.371 bits (516), Expect = 1.054e-58 Identity = 89/195 (45.64%), Postives = 139/195 (71.28%), Query Frame = 3
Query: 2997 ISISHSSIDKNEEIIKAVKTEVNLMIQLNHPNVLPLLGAMFSPTDNIISMFVRWMPGGSVASLLNQYSAFLEPVTLAYALQTARGLSYIHSNRILHRDLKGANLLLDSSGMRLRISDFGASARLSNGRDSNASDFKGQLLGTVAFMAPEVLRGEEYGRSCDVWSFACCIIEMLTGSQPWRDRNHTNHLALMYTIA 3581
+S +S + +++ + + E+ ++ +L HP+++ LGA + ++F+ WM GGS++ LL++Y F E + + Y Q +G+SY+H N+++HRD+KGAN+L+DS+G +RI+DFGA+ARL+ + + A +F+GQLLGT+AFMAPEVLRGE YGRSCDVWS C +IEM TG PW H+NHLAL++ ++
Sbjct: 70 VSFCRNSKSEQDKVCQTIMDEIAILARLKHPHLIKCLGA--TRHTGHFNIFLEWMAGGSISMLLSKYGPFEEAILIRYLRQILQGVSYLHENQVVHRDIKGANILVDSTGQDIRIADFGAAARLAT-QITGAGEFQGQLLGTIAFMAPEVLRGESYGRSCDVWSVGCVLIEMATGKPPWNAHEHSNHLALIFKVS 261
BLAST of MAP3K-1 vs. Ensembl Nematostella
Match: EDO47821 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RL88]) HSP 1 Score: 185.652 bits (470), Expect = 1.333e-52 Identity = 93/265 (35.09%), Postives = 155/265 (58.49%), Query Frame = 3
Query: 2901 EWCQGPLLGTGAFSKCYQGRDVRTGLLMAVKQISISHSSIDKNEEIIKAVKTEVNLMIQLNHPNVLPLLGAMFSPTDNIISMFVRWMPGGSVASLLNQYSAFLEPVTLAYALQTARGLSYIHSNRILHRDLKGANLLLDSSGMRLRISDFGASARLSN-GRDSNASDFKGQLLGTVAFMAPEVLRGEEYGRSCDVWSFACCIIEMLTGSQPWRDRNHTNHLALMYTIASAEEPPKLPEQISADLTELLTDCLNRDPKKRPLSSKL 3692
EW +G +LG GAF + G V TG L+AVKQ+ + +++D E + ++ EV L+ L H N++ +G + I++F+ ++PGGS+A L ++ AF+EPV Y Q G+SY+H+N ++HRD+KG N++L +G+ +++ DFG + ++ G + S+ + GT +MAPEV+R +GR D+WS C + EM TG PW ++ L+ ++ I + P+L E SA + +T C+ RD RP + +L
Sbjct: 4 EWQKGNVLGKGAFGTVFLGL-VNTGELIAVKQVELHPNNVDAAERQYEKLQEEVGLLKSLKHKNIVQYIGTCMDDSQCTINIFMEFVPGGSIAQALKRFGAFVEPVFRRYTRQILDGVSYLHNNNVIHRDIKGGNIMLMPNGV-IKLIDFGCAKKICMVGAHVSKSNILRSMRGTPYWMAPEVIRETGHGRKSDIWSIGCTVFEMATGQPPW---SNVPPLSAIFAIGNGSPVPRLDESFSAAAIDFVTSCMTRDQDTRPSADEL 263
BLAST of MAP3K-1 vs. Ensembl Nematostella
Match: EDO41410 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S4G7]) HSP 1 Score: 183.341 bits (464), Expect = 7.174e-52 Identity = 103/265 (38.87%), Postives = 154/265 (58.11%), Query Frame = 3
Query: 2904 WCQGPLLGTGAFSKCYQGRDVRTGLLMAVKQISISH-SSIDKNEEIIKAVKTEVNLMIQLNHPNVLPLLGAMFSPTDNI-ISMFVRWMPGGSVASLLNQYSAFLEPVTLAYALQTARGLSYIHSNRILHRDLKGANLLLDSSGMRLRISDFGASARLSNGRDSNASDFKGQLLGTVAFMAPEVLRGEEYGRSCDVWSFACCIIEMLTGSQPWRDRNHTNHLALMYTIASAEEPPKLPEQISADLTELLTDCLNRDPKKRPLSSKL 3692
W +G LLG GAF + Y D+ TG +AVKQI +S KNE +KA++ E+ M + ++ G TD++ I +F+ ++PGGS+ + Q+ A E +T Y+ Q G+ Y+H+NRI+HRD+KGAN+L D G ++++DFGAS RL R + + F+ + GT +MAPEV+ GE YGR DVWS C ++EMLT PW D +A ++ IA+ P+LP +S D E + L + K RP + +L
Sbjct: 4 WRKGKLLGAGAFGQVYMCHDLDTGRELAVKQIETGQLNSSTKNE--VKALEGEIEFMKAFRNERIVQYYGI---ETDDLHIYIFMEYLPGGSIHEHIKQHGALNESLTRKYSRQILEGILYLHTNRIVHRDIKGANILRDLYG-NVKLADFGASKRLQTIR--SKTGFR-SVHGTPYWMAPEVINGEGYGRKADVWSVGCTVVEMLTTKPPWAD---FEPMAALFKIATQPTEPELPSDLSVDAVEFVRSTLRMNSKSRPSADEL 256
BLAST of MAP3K-1 vs. Ensembl Nematostella
Match: EDO47144 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RMS1]) HSP 1 Score: 131.724 bits (330), Expect = 8.573e-34 Identity = 86/266 (32.33%), Postives = 138/266 (51.88%), Query Frame = 3
Query: 2922 LGTGAFSKCYQGRDVRTGLLMAVKQISISHSSIDKNEEIIKAVKTEVNLMIQLNHPNVLPLLGAMFSPTDNIISMFVRWMPGGSVASLLN-QYSAFLEPV-----TLAYALQTARGLSYIHSNR---ILHRDLKGANLLLDSSGMRLRISDFGASARLSNGRDSNASDFKGQLLGTVAFMAPEVLRGEEYGRSCDVWSFACCIIEMLTGSQPWRDRNHTNHLALMYTIASAEEPPKLPEQISADLTELLTDCLNRDPKKRPLSSKL 3692
+G GAF Y+ R R ++AVK I ++E KA EV + +++H N++ L GA+ + + + + GGS+ +LL+ + S P+ +++ALQ A G+ Y+HS + I+HRDLK NLLL G ++I DFG + L +N G+ A+MAPEV G Y CDV+SF + EM++ +P+ D + +M+ + PP L + I + EL+T C ++DP KRP S++
Sbjct: 14 VGHGAFGVVYKAR-WREKFIVAVKTI--------ESEAEKKAFIVEVQQLSRVSHRNIIKLYGAV--TKHEPVCLVMEYAEGGSLYNLLHWKKSTSRAPIYTASHVISWALQCASGVEYLHSMKPKAIIHRDLKPPNLLLTRCGTVVKICDFGTACDLKTYMTNNK--------GSAAWMAPEVFEGNNYTEKCDVYSFGIILWEMISRRKPFDDMAGSPPFRIMWAVHIGRRPP-LIKNIPKPIEELITSCWDKDPDKRPSFSRI 259
BLAST of MAP3K-1 vs. Ensembl Medaka
Match: map3k3 (mitogen-activated protein kinase kinase kinase 3 [Source:NCBI gene;Acc:101169290]) HSP 1 Score: 180.644 bits (457), Expect = 4.229e-47 Identity = 100/263 (38.02%), Postives = 146/263 (55.51%), Query Frame = 3
Query: 2904 WCQGPLLGTGAFSKCYQGRDVRTGLLMAVKQISISHSSIDKNEEIIKAVKTEVNLMIQLNHPNVLPLLGAMFSPTDNIISMFVRWMPGGSVASLLNQYSAFLEPVTLAYALQTARGLSYIHSNRILHRDLKGANLLLDSSGMRLRISDFGASARLSNGRDSNASDFKGQLLGTVAFMAPEVLRGEEYGRSCDVWSFACCIIEMLTGSQPWRDRNHTNHLALMYTIASAEEPPKLPEQISADLTELLTDCLNRDPKKRPLSSKL 3692
W +G LLG GAF Y DV TG +A KQ+ S + ++E+ A++ E+ L+ L+H ++ G + ++ +++F+ +MPGGSV L Y A E VT Y Q G+SY+HSN I+HRD+KGAN+L DS+G +++ DFGAS RL S + GT +M+PEV+ GE YGR DVWS C ++EMLT PW + +A ++ IA+ P LP S D C+ + K RP + +L
Sbjct: 353 WRRGKLLGQGAFGLVYLCYDVDTGRELAAKQVQFDPDSPETSKEV-SALECEIQLLKNLHHERIVQYYGCLRDHSEKTLTIFMEYMPGGSVKDQLKAYGALTENVTRKYTRQILEGMSYLHSNMIVHRDIKGANILRDSAG-NVKLGDFGASKRLQTICMSGTG--IRSVTGTPYWMSPEVISGEGYGRKADVWSLGCTVVEMLTEKPPWAE---YEAMAAIFKIATQPTNPLLPSHTS-DQARDFIHCIFVEAKHRPSAEEL 607
BLAST of MAP3K-1 vs. Ensembl Medaka
Match: map3k22 (mitogen-activated protein kinase kinase kinase 3 [Source:NCBI gene;Acc:101156127]) HSP 1 Score: 177.948 bits (450), Expect = 2.123e-46 Identity = 96/244 (39.34%), Postives = 138/244 (56.56%), Query Frame = 3
Query: 2889 RSGYEWCQGPLLGTGAFSKCYQGRDVRTGLLMAVKQISISHSSIDKNEEIIKAVKTEVNLMIQLNHPNVLPLLGAMFSPTDNIISMFVRWMPGGSVASLLNQYSAFLEPVTLAYALQTARGLSYIHSNRILHRDLKGANLLLDSSGMRLRISDFGASARLSNGRDSNASDFKGQLLGTVAFMAPEVLRGEEYGRSCDVWSFACCIIEMLTGSQPWRDRNHTNHLALMYTIASAEEPPKLPEQIS 3620
R+ W QG LLG GAF + Y D TG +A KQ+ + ++E+ A++ E+ L+ L H ++ G + +++FV +MPGGS+ L Y A E VT Y Q +G+SY+HSN I+HRD+KGAN+L DSSG +++ DFGAS R+ S + GT +M+PEV+ GE YGR DVWS AC ++EMLT PW + +A ++ IA+ P LPE +S
Sbjct: 322 RAPVNWRQGKLLGRGAFGEVYLCYDADTGRELAAKQVPFDPDCQETSKEV-NALECEIQLLKNLRHDRIVQYYGCLRDLDQRKLTIFVEFMPGGSIKDQLKAYGALTEKVTRRYTRQILQGVSYLHSNMIVHRDIKGANILRDSSG-NVKLGDFGASKRIQTICMSGTG--IKSVTGTPYWMSPEVINGEGYGRKADVWSVACTVVEMLTQKPPWAE---YEAMAAIFKIATQPTKPTLPEGVS 558
BLAST of MAP3K-1 vs. Ensembl Medaka
Match: map3k2 (mitogen-activated protein kinase kinase kinase 2 [Source:NCBI gene;Acc:101160297]) HSP 1 Score: 178.718 bits (452), Expect = 2.732e-46 Identity = 113/321 (35.20%), Postives = 163/321 (50.78%), Query Frame = 3
Query: 2781 IFRKILAEQTNSMDRKDSLDIESQPPPGLGVF---------SSEYRSGYEWCQGPLLGTGAFSKCYQGRDVRTGLLMAVKQISISHSSIDKNEEIIKAVKTEVNLMIQLNHPNVLPLLGAMFSPTDNIISMFVRWMPGGSVASLLNQYSAFLEPVTLAYALQTARGLSYIHSNRILHRDLKGANLLLDSSGMRLRISDFGASARLSNGRDSNASDFKGQLLGTVAFMAPEVLRGEEYGRSCDVWSFACCIIEMLTGSQPWRDRNHTNHLALMYTIASAEEPPKLPEQISADLTELLTDCLNRDPKKRPLSSKLESYRVFKH 3716
+F L E R+ DIES P G S R+ W G LLG GAF + Y D TG +AVKQ+ S + ++E+ A++ E+ L+ L H ++ G + + +S+F+ MPGGS+ L Y A E VT Y Q G+SY+HSN I+HRD+KGAN+L DS G +++ DFGAS RL S + GT +M+PEV+ GE YGR D+WS C ++EMLT PW + +A ++ IA+ P+LP +S E L + K+RP + +L + +F H
Sbjct: 339 VFTPDLEEAPGPARRRRGSDIESNANPSAGPTLSVMDISPPSRSPRAPTNWRLGKLLGQGAFGRVYLCYDADTGRELAVKQVQFDPESPETSKEV-SALECEIQLLKNLCHERIVQYYGCLRDTMERTLSIFMEHMPGGSIKDQLKSYGALTENVTRRYTRQILEGVSYLHSNMIVHRDIKGANILRDSVG-NVKLGDFGASRRLQTICLSGTG--IKSVTGTPYWMSPEVISGEGYGRKADIWSVGCTVVEMLTQRPPWAE---FEAMAAIFKIATQPTNPELPVHVSDHCREFLRRIF-VETKQRPSADELLRH-IFVH 650
BLAST of MAP3K-1 vs. Ensembl Medaka
Match: map3k22 (mitogen-activated protein kinase kinase kinase 3 [Source:NCBI gene;Acc:101156127]) HSP 1 Score: 177.948 bits (450), Expect = 2.991e-46 Identity = 97/244 (39.75%), Postives = 140/244 (57.38%), Query Frame = 3
Query: 2889 RSGYEWCQGPLLGTGAFSKCYQGRDVRTGLLMAVKQISISHSSIDKNEEIIKAVKTEVNLMIQLNHPNVLPLLGAMFSPTDNIISMFVRWMPGGSVASLLNQYSAFLEPVTLAYALQTARGLSYIHSNRILHRDLKGANLLLDSSGMRLRISDFGASARLSNGRDSNASDFKGQLLGTVAFMAPEVLRGEEYGRSCDVWSFACCIIEMLTGSQPWRDRNHTNHLALMYTIASAEEPPKLPEQIS 3620
R+ W QG LLG GAF + Y D TG +A KQ+ + ++E+ A++ E+ L+ L H ++ G + +++FV +MPGGS+ L Y A E VT Y Q +G+SY+HSN I+HRD+KGAN+L DSSG +++ DFGAS R+ S + K + GT +M+PEV+ GE YGR DVWS AC ++EMLT PW + +A ++ IA+ P LPE +S
Sbjct: 352 RAPVNWRQGKLLGRGAFGEVYLCYDADTGRELAAKQVPFDPDCQETSKEV-NALECEIQLLKNLRHDRIVQYYGCLRDLDQRKLTIFVEFMPGGSIKDQLKAYGALTEKVTRRYTRQILQGVSYLHSNMIVHRDIKGANILRDSSG-NVKLGDFGASKRIQTICMS-GTGIKS-VTGTPYWMSPEVINGEGYGRKADVWSVACTVVEMLTQKPPWAE---YEAMAAIFKIATQPTKPTLPEGVS 588
BLAST of MAP3K-1 vs. Ensembl Medaka
Match: map3k22 (mitogen-activated protein kinase kinase kinase 3 [Source:NCBI gene;Acc:101156127]) HSP 1 Score: 177.948 bits (450), Expect = 2.991e-46 Identity = 97/244 (39.75%), Postives = 140/244 (57.38%), Query Frame = 3
Query: 2889 RSGYEWCQGPLLGTGAFSKCYQGRDVRTGLLMAVKQISISHSSIDKNEEIIKAVKTEVNLMIQLNHPNVLPLLGAMFSPTDNIISMFVRWMPGGSVASLLNQYSAFLEPVTLAYALQTARGLSYIHSNRILHRDLKGANLLLDSSGMRLRISDFGASARLSNGRDSNASDFKGQLLGTVAFMAPEVLRGEEYGRSCDVWSFACCIIEMLTGSQPWRDRNHTNHLALMYTIASAEEPPKLPEQIS 3620
R+ W QG LLG GAF + Y D TG +A KQ+ + ++E+ A++ E+ L+ L H ++ G + +++FV +MPGGS+ L Y A E VT Y Q +G+SY+HSN I+HRD+KGAN+L DSSG +++ DFGAS R+ S + K + GT +M+PEV+ GE YGR DVWS AC ++EMLT PW + +A ++ IA+ P LPE +S
Sbjct: 352 RAPVNWRQGKLLGRGAFGEVYLCYDADTGRELAAKQVPFDPDCQETSKEV-NALECEIQLLKNLRHDRIVQYYGCLRDLDQRKLTIFVEFMPGGSIKDQLKAYGALTEKVTRRYTRQILQGVSYLHSNMIVHRDIKGANILRDSSG-NVKLGDFGASKRIQTICMS-GTGIKS-VTGTPYWMSPEVINGEGYGRKADVWSVACTVVEMLTQKPPWAE---YEAMAAIFKIATQPTKPTLPEGVS 588
BLAST of MAP3K-1 vs. Planmine SMEST
Match: SMESG000054386.1 (SMESG000054386.1) HSP 1 Score: 2371.66 bits (6145), Expect = 0.000e+0 Identity = 1211/1213 (99.84%), Postives = 1211/1213 (99.84%), Query Frame = 3
Query: 87 MSSNISKQNFSRSISVKPQKNAFEYGNDGELTTIYLNYPRELXXXXXXXXXXXXXXXXPIKYRKSSSRTNTPFNATRSSSYHALSSSNQILEDSSKNDHNYRQSNIQEKLKIISQQNFCILPQCSPTSFTVCAGSSSRYVVNIGPQXXXXXXXXXXXXNQHSFPCVHLLFIMCKVLQVHERDPLLLEKHLKNIEVDELFKRFNKRIKEKLNNPYRPNDKNCKNINHEEEHEGNTSRFGRDATSFGLQYKSVMKNMMAHVLEKCRNKNKHDCDEPRPNESLDEITCSICLQEMNIAQLLIFCHNCSNEFHKKCILIWLKECKKNNEELTCPLCRKSWPSDDISRDIVSPLEYGPSVADSNFFVPRSHSTATSFQHINHREITNIAXXXXXXXXXXXXXXINGSKHGFSVSSNHKPIGYCFSALVAEMLSSDMSDKREAGLRQVAEQTVQIVVSAGSAYSVEDNKVNCMSDTISTDIVSSMGGFTTGLMLKEAFRVIARLLDDTSYTLFVGALRAFREILGYLICRTESEVERMSRMISPVLCQLLRICGDNSQKKKAQMCLSALFELANGQEGGMALGREIKKSSLPVTGWQRLAKFAIANHHRFKAVHCYGRLSLLERLLDKFELTLDILRKLLEFVTSQLLLMHRSMHLLNSFDSGKMDVLETTDVDTGLSTSDIRLLSGQRLQKLAKILFINTAKLMMSKLKFNGWSSHDVYVELWKDLNRLPQPWKEKFMIKLKIPWEKFINVELTEVDKSLQNREKKRPEVTPATVTPSCVSKSYRISKRYSQSKPVGAASKIGGIQSANSVNSLKVRTGSVSQTIRSASSGSCRISPFIRITPEPAYDAVPLSESEDDISHETSSVFFSELAIHNSIYGHQFGLQXXXXXXXXXXXXMKRTNAIFRKILAEQTNSMDRKDSLDIESQPPPGLGVFSSEYRSGYEWCQGPLLGTGAFSKCYQGRDVRTGLLMAVKQISISHSSIDKNEEIIKAVKTEVNLMIQLNHPNVLPLLGAMFSPTDNIISMFVRWMPGGSVASLLNQYSAFLEPVTLAYALQTARGLSYIHSNRILHRDLKGANLLLDSSGMRLRISDFGASARLSNGRDSNASDFKGQLLGTVAFMAPEVLRGEEYGRSCDVWSFACCIIEMLTGSQPWRDRNHTNHLALMYTIASAEEPPKLPEQISADLTELLTDCLNRDPKKRPLSSKLESYRVFKHLTS 3725
MSSNISKQNFSRSISVKPQKNAFEYGNDGELTTIYLNYPRELSRSTSTSKVSSKSQTKPIKYRKSSSRTNTPFNATRSSSYHALSSSNQILEDSSKNDHNYRQS IQEKLKIISQQNFCILPQCSPTSFTVCAGSSSRYVVNIGPQTCCCLTKSST SNQHSFPCVHLLFIMCKVLQVHERDPLLLEKHLKNIEVDELFKRFNKRIKEKLNNPYRPNDKNCKNINHEEEHEGNTSRFGRDATSFGLQYKSVMKNMMAHVLEKCRNKNKHDCDEPRPNESLDEITCSICLQEMNIAQLLIFCHNCSNEFHKKCILIWLKECKKNNEELTCPLCRKSWPSDDISRDIVSPLEYGPSVADSNFFVPRSHSTATSFQHINHREITNIASSTSDLTSSNFSFNINGSKHGFSVSSNHKPIGYCFSALVAEMLSSDMSDKREAGLRQVAEQTVQIVVSAGSAYSVEDNKVNCMSDTISTDIVSSMGGFTTGLMLKEAFRVIARLLDDTSYTLFVGALRAFREILGYLICRTESEVERMSRMISPVLCQLLRICGDNSQKKKAQMCLSALFELANGQEGGMALGREIKKSSLPVTGWQRLAKFAIANHHRFKAVHCYGRLSLLERLLDKFELTLDILRKLLEFVTSQLLLMHRSMHLLNSFDSGKMDVLETTDVDTGLSTSDIRLLSGQRLQKLAKILFINTAKLMMSKLKFNGWSSHDVYVELWKDLNRLPQPWKEKFMIKLKIPWEKFINVELTEVDKSLQNREKKRPEVTPATVTPSCVSKSYRISKRYSQSKPVGAASKIGGIQSANSVNSLKVRTGSVSQTIRSASSGSCRISPFIRITPEPAYDAVPLSESEDDISHETSSVFFSELAIHNSIYGHQFGLQESSSDERNEEEEMKRTNAIFRKILAEQTNSMDRKDSLDIESQPPPGLGVFSSEYRSGYEWCQGPLLGTGAFSKCYQGRDVRTGLLMAVKQISISHSSIDKNEEIIKAVKTEVNLMIQLNHPNVLPLLGAMFSPTDNIISMFVRWMPGGSVASLLNQYSAFLEPVTLAYALQTARGLSYIHSNRILHRDLKGANLLLDSSGMRLRISDFGASARLSNGRDSNASDFKGQLLGTVAFMAPEVLRGEEYGRSCDVWSFACCIIEMLTGSQPWRDRNHTNHLALMYTIASAEEPPKLPEQISADLTELLTDCLNRDPKKRPLSSKLESYRVFKHLTS
Sbjct: 1 MSSNISKQNFSRSISVKPQKNAFEYGNDGELTTIYLNYPRELSRSTSTSKVSSKSQTKPIKYRKSSSRTNTPFNATRSSSYHALSSSNQILEDSSKNDHNYRQSKIQEKLKIISQQNFCILPQCSPTSFTVCAGSSSRYVVNIGPQTCCCLTKSSTGSNQHSFPCVHLLFIMCKVLQVHERDPLLLEKHLKNIEVDELFKRFNKRIKEKLNNPYRPNDKNCKNINHEEEHEGNTSRFGRDATSFGLQYKSVMKNMMAHVLEKCRNKNKHDCDEPRPNESLDEITCSICLQEMNIAQLLIFCHNCSNEFHKKCILIWLKECKKNNEELTCPLCRKSWPSDDISRDIVSPLEYGPSVADSNFFVPRSHSTATSFQHINHREITNIASSTSDLTSSNFSFNINGSKHGFSVSSNHKPIGYCFSALVAEMLSSDMSDKREAGLRQVAEQTVQIVVSAGSAYSVEDNKVNCMSDTISTDIVSSMGGFTTGLMLKEAFRVIARLLDDTSYTLFVGALRAFREILGYLICRTESEVERMSRMISPVLCQLLRICGDNSQKKKAQMCLSALFELANGQEGGMALGREIKKSSLPVTGWQRLAKFAIANHHRFKAVHCYGRLSLLERLLDKFELTLDILRKLLEFVTSQLLLMHRSMHLLNSFDSGKMDVLETTDVDTGLSTSDIRLLSGQRLQKLAKILFINTAKLMMSKLKFNGWSSHDVYVELWKDLNRLPQPWKEKFMIKLKIPWEKFINVELTEVDKSLQNREKKRPEVTPATVTPSCVSKSYRISKRYSQSKPVGAASKIGGIQSANSVNSLKVRTGSVSQTIRSASSGSCRISPFIRITPEPAYDAVPLSESEDDISHETSSVFFSELAIHNSIYGHQFGLQESSSDERNEEEEMKRTNAIFRKILAEQTNSMDRKDSLDIESQPPPGLGVFSSEYRSGYEWCQGPLLGTGAFSKCYQGRDVRTGLLMAVKQISISHSSIDKNEEIIKAVKTEVNLMIQLNHPNVLPLLGAMFSPTDNIISMFVRWMPGGSVASLLNQYSAFLEPVTLAYALQTARGLSYIHSNRILHRDLKGANLLLDSSGMRLRISDFGASARLSNGRDSNASDFKGQLLGTVAFMAPEVLRGEEYGRSCDVWSFACCIIEMLTGSQPWRDRNHTNHLALMYTIASAEEPPKLPEQISADLTELLTDCLNRDPKKRPLSSKLESYRVFKHLTS 1213
BLAST of MAP3K-1 vs. Planmine SMEST
Match: SMESG000054386.1 (SMESG000054386.1) HSP 1 Score: 2305.02 bits (5972), Expect = 0.000e+0 Identity = 1186/1213 (97.77%), Postives = 1186/1213 (97.77%), Query Frame = 3
Query: 87 MSSNISKQNFSRSISVKPQKNAFEYGNDGELTTIYLNYPRELXXXXXXXXXXXXXXXXPIKYRKSSSRTNTPFNATRSSSYHALSSSNQILEDSSKNDHNYRQSNIQEKLKIISQQNFCILPQCSPTSFTVCAGSSSRYVVNIGPQXXXXXXXXXXXXNQHSFPCVHLLFIMCKVLQVHERDPLLLEKHLKNIEVDELFKRFNKRIKEKLNNPYRPNDKNCKNINHEEEHEGNTSRFGRDATSFGLQYKSVMKNMMAHVLEKCRNKNKHDCDEPRPNESLDEITCSICLQEMNIAQLLIFCHNCSNEFHKKCILIWLKECKKNNEELTCPLCRKSWPSDDISRDIVSPLEYGPSVADSNFFVPRSHSTATSFQHINHREITNIAXXXXXXXXXXXXXXINGSKHGFSVSSNHKPIGYCFSALVAEMLSSDMSDKREAGLRQVAEQTVQIVVSAGSAYSVEDNKVNCMSDTISTDIVSSMGGFTTGLMLKEAFRVIARLLDDTSYTLFVGALRAFREILGYLICRTESEVERMSRMISPVLCQLLRICGDNSQKKKAQMCLSALFELANGQEGGMALGREIKKSSLPVTGWQRLAKFAIANHHRFKAVHCYGRLSLLERLLDKFELTLDILRKLLEFVTSQLLLMHRSMHLLNSFDSGKMDVLETTDVDTGLSTSDIRLLSGQRLQKLAKILFINTAKLMMSKLKFNGWSSHDVYVELWKDLNRLPQPWKEKFMIKLKIPWEKFINVELTEVDKSLQNREKKRPEVTPATVTPSCVSKSYRISKRYSQSKPVGAASKIGGIQSANSVNSLKVRTGSVSQTIRSASSGSCRISPFIRITPEPAYDAVPLSESEDDISHETSSVFFSELAIHNSIYGHQFGLQXXXXXXXXXXXXMKRTNAIFRKILAEQTNSMDRKDSLDIESQPPPGLGVFSSEYRSGYEWCQGPLLGTGAFSKCYQGRDVRTGLLMAVKQISISHSSIDKNEEIIKAVKTEVNLMIQLNHPNVLPLLGAMFSPTDNIISMFVRWMPGGSVASLLNQYSAFLEPVTLAYALQTARGLSYIHSNRILHRDLKGANLLLDSSGMRLRISDFGASARLSNGRDSNASDFKGQLLGTVAFMAPEVLRGEEYGRSCDVWSFACCIIEMLTGSQPWRDRNHTNHLALMYTIASAEEPPKLPEQISADLTELLTDCLNRDPKKRPLSSKLESYRVFKHLTS 3725
MSSNISKQNFSRSISVKPQKNAFEYGNDGELTTIYLNYPRELSRSTSTSKVSSKSQTKPIKYRKSSSRTNTPFNATRSSSYHALSSSNQILEDSSKNDHNYRQS IQEKLKIISQQNFCILPQCSPTSFTVCAGSSSRYVVNIGPQTCCCLTKSST SNQHSFPCVHLLFIMCKVLQVHERDPLLLEKHLKNIEVDELFKRFNKRIKEKLNNPYRPNDKNCKNINHEEEHEGNTSRFGR NKNKHDCDEPRPNESLDEITCSICLQEMNIAQLLIFCHNCSNEFHKKCILIWLKECKKNNEELTCPLCRKSWPSDDISRDIVSPLEYGPSVADSNFFVPRSHSTATSFQHINHREITNIASSTSDLTSSNFSFNINGSKHGFSVSSNHKPIGYCFSALVAEMLSSDMSDKREAGLRQVAEQTVQIVVSAGSAYSVEDNKVNCMSDTISTDIVSSMGGFTTGLMLKEAFRVIARLLDDTSYTLFVGALRAFREILGYLICRTESEVERMSRMISPVLCQLLRICGDNSQKKKAQMCLSALFELANGQEGGMALGREIKKSSLPVTGWQRLAKFAIANHHRFKAVHCYGRLSLLERLLDKFELTLDILRKLLEFVTSQLLLMHRSMHLLNSFDSGKMDVLETTDVDTGLSTSDIRLLSGQRLQKLAKILFINTAKLMMSKLKFNGWSSHDVYVELWKDLNRLPQPWKEKFMIKLKIPWEKFINVELTEVDKSLQNREKKRPEVTPATVTPSCVSKSYRISKRYSQSKPVGAASKIGGIQSANSVNSLKVRTGSVSQTIRSASSGSCRISPFIRITPEPAYDAVPLSESEDDISHETSSVFFSELAIHNSIYGHQFGLQESSSDERNEEEEMKRTNAIFRKILAEQTNSMDRKDSLDIESQPPPGLGVFSSEYRSGYEWCQGPLLGTGAFSKCYQGRDVRTGLLMAVKQISISHSSIDKNEEIIKAVKTEVNLMIQLNHPNVLPLLGAMFSPTDNIISMFVRWMPGGSVASLLNQYSAFLEPVTLAYALQTARGLSYIHSNRILHRDLKGANLLLDSSGMRLRISDFGASARLSNGRDSNASDFKGQLLGTVAFMAPEVLRGEEYGRSCDVWSFACCIIEMLTGSQPWRDRNHTNHLALMYTIASAEEPPKLPEQISADLTELLTDCLNRDPKKRPLSSKLESYRVFKHLTS
Sbjct: 1 MSSNISKQNFSRSISVKPQKNAFEYGNDGELTTIYLNYPRELSRSTSTSKVSSKSQTKPIKYRKSSSRTNTPFNATRSSSYHALSSSNQILEDSSKNDHNYRQSKIQEKLKIISQQNFCILPQCSPTSFTVCAGSSSRYVVNIGPQTCCCLTKSSTGSNQHSFPCVHLLFIMCKVLQVHERDPLLLEKHLKNIEVDELFKRFNKRIKEKLNNPYRPNDKNCKNINHEEEHEGNTSRFGR-------------------------NKNKHDCDEPRPNESLDEITCSICLQEMNIAQLLIFCHNCSNEFHKKCILIWLKECKKNNEELTCPLCRKSWPSDDISRDIVSPLEYGPSVADSNFFVPRSHSTATSFQHINHREITNIASSTSDLTSSNFSFNINGSKHGFSVSSNHKPIGYCFSALVAEMLSSDMSDKREAGLRQVAEQTVQIVVSAGSAYSVEDNKVNCMSDTISTDIVSSMGGFTTGLMLKEAFRVIARLLDDTSYTLFVGALRAFREILGYLICRTESEVERMSRMISPVLCQLLRICGDNSQKKKAQMCLSALFELANGQEGGMALGREIKKSSLPVTGWQRLAKFAIANHHRFKAVHCYGRLSLLERLLDKFELTLDILRKLLEFVTSQLLLMHRSMHLLNSFDSGKMDVLETTDVDTGLSTSDIRLLSGQRLQKLAKILFINTAKLMMSKLKFNGWSSHDVYVELWKDLNRLPQPWKEKFMIKLKIPWEKFINVELTEVDKSLQNREKKRPEVTPATVTPSCVSKSYRISKRYSQSKPVGAASKIGGIQSANSVNSLKVRTGSVSQTIRSASSGSCRISPFIRITPEPAYDAVPLSESEDDISHETSSVFFSELAIHNSIYGHQFGLQESSSDERNEEEEMKRTNAIFRKILAEQTNSMDRKDSLDIESQPPPGLGVFSSEYRSGYEWCQGPLLGTGAFSKCYQGRDVRTGLLMAVKQISISHSSIDKNEEIIKAVKTEVNLMIQLNHPNVLPLLGAMFSPTDNIISMFVRWMPGGSVASLLNQYSAFLEPVTLAYALQTARGLSYIHSNRILHRDLKGANLLLDSSGMRLRISDFGASARLSNGRDSNASDFKGQLLGTVAFMAPEVLRGEEYGRSCDVWSFACCIIEMLTGSQPWRDRNHTNHLALMYTIASAEEPPKLPEQISADLTELLTDCLNRDPKKRPLSSKLESYRVFKHLTS 1188
BLAST of MAP3K-1 vs. Planmine SMEST
Match: SMESG000004938.1 (SMESG000004938.1) HSP 1 Score: 159.458 bits (402), Expect = 6.089e-39 Identity = 94/268 (35.07%), Postives = 143/268 (53.36%), Query Frame = 3
Query: 2910 QGPLLGTGAFSKCYQGRDVRTGLLMAVKQISISHSSIDKNEEIIKAVK---TEVNLMIQLNHPNVLPLLGAMFSPTDNIISMFVRWMPGGSVASLLNQYSAFLEPVTLAYALQTARGLSYIHSNRILHRDLKGANLLLDSSGMRLRISDFGASARLSNGRDSNASDFKGQLLGTVAFMAPEVLRGEE-YGRSCDVWSFACCIIEMLTGSQPWRDRNHTNHLALMYTIASAEEPPKLPEQISADLTELLTDCLNRDPKKRPLSSKLESY 3701
Q +LG G F + GR++ + +A+K++ NE IK V+ E+ L +L+H N++ LG+ + + + +PGGS+ SLL + A E T Y+ Q GL Y+H NRI+HRD+KG N+L++ L+ISDFG S RL + AS F GT+ +MAPE+++G YG DVWSF C +IEMLTG P+ D +A ++ + + P P+ +S + + L C DP KR + L S+
Sbjct: 662 QRIVLGRGTFGTVFAGRELTKQIKIAIKEV---------NESQIKEVQPLHEEIWLHSRLSHRNIVSYLGS--RSEKGVFKIIMEQVPGGSLTSLLKKNGALTEETTSYYSNQILEGLKYLHDNRIMHRDIKGDNVLVNMYNGILKISDFGTSKRLGDIM-QRASTFT----GTMQYMAPELIKGPSGYGFPADVWSFGCTVIEMLTGKPPFNDLG--TPIAALFKVGEFSQHPDFPDHLSHEAIDFLEKCFIPDPNKRATVTSLLSH 911
BLAST of MAP3K-1 vs. Planmine SMEST
Match: SMESG000004938.1 (SMESG000004938.1) HSP 1 Score: 159.073 bits (401), Expect = 7.178e-39 Identity = 94/268 (35.07%), Postives = 143/268 (53.36%), Query Frame = 3
Query: 2910 QGPLLGTGAFSKCYQGRDVRTGLLMAVKQISISHSSIDKNEEIIKAVK---TEVNLMIQLNHPNVLPLLGAMFSPTDNIISMFVRWMPGGSVASLLNQYSAFLEPVTLAYALQTARGLSYIHSNRILHRDLKGANLLLDSSGMRLRISDFGASARLSNGRDSNASDFKGQLLGTVAFMAPEVLRGEE-YGRSCDVWSFACCIIEMLTGSQPWRDRNHTNHLALMYTIASAEEPPKLPEQISADLTELLTDCLNRDPKKRPLSSKLESY 3701
Q +LG G F + GR++ + +A+K++ NE IK V+ E+ L +L+H N++ LG+ + + + +PGGS+ SLL + A E T Y+ Q GL Y+H NRI+HRD+KG N+L++ L+ISDFG S RL + AS F GT+ +MAPE+++G YG DVWSF C +IEMLTG P+ D +A ++ + + P P+ +S + + L C DP KR + L S+
Sbjct: 662 QRIVLGRGTFGTVFAGRELTKQIKIAIKEV---------NESQIKEVQPLHEEIWLHSRLSHRNIVSYLGS--RSEKGVFKIIMEQVPGGSLTSLLKKNGALTEETTSYYSNQILEGLKYLHDNRIMHRDIKGDNVLVNMYNGILKISDFGTSKRLGDIM-QRASTFT----GTMQYMAPELIKGPSGYGFPADVWSFGCTVIEMLTGKPPFNDLG--TPIAALFKVGEFSQHPDFPDHLSHEAIDFLEKCFIPDPNKRATVTSLLSH 911
BLAST of MAP3K-1 vs. Planmine SMEST
Match: SMESG000004938.1 (SMESG000004938.1) HSP 1 Score: 159.073 bits (401), Expect = 7.205e-39 Identity = 94/268 (35.07%), Postives = 143/268 (53.36%), Query Frame = 3
Query: 2910 QGPLLGTGAFSKCYQGRDVRTGLLMAVKQISISHSSIDKNEEIIKAVK---TEVNLMIQLNHPNVLPLLGAMFSPTDNIISMFVRWMPGGSVASLLNQYSAFLEPVTLAYALQTARGLSYIHSNRILHRDLKGANLLLDSSGMRLRISDFGASARLSNGRDSNASDFKGQLLGTVAFMAPEVLRGEE-YGRSCDVWSFACCIIEMLTGSQPWRDRNHTNHLALMYTIASAEEPPKLPEQISADLTELLTDCLNRDPKKRPLSSKLESY 3701
Q +LG G F + GR++ + +A+K++ NE IK V+ E+ L +L+H N++ LG+ + + + +PGGS+ SLL + A E T Y+ Q GL Y+H NRI+HRD+KG N+L++ L+ISDFG S RL + AS F GT+ +MAPE+++G YG DVWSF C +IEMLTG P+ D +A ++ + + P P+ +S + + L C DP KR + L S+
Sbjct: 662 QRIVLGRGTFGTVFAGRELTKQIKIAIKEV---------NESQIKEVQPLHEEIWLHSRLSHRNIVSYLGS--RSEKGVFKIIMEQVPGGSLTSLLKKNGALTEETTSYYSNQILEGLKYLHDNRIMHRDIKGDNVLVNMYNGILKISDFGTSKRLGDIM-QRASTFT----GTMQYMAPELIKGPSGYGFPADVWSFGCTVIEMLTGKPPFNDLG--TPIAALFKVGEFSQHPDFPDHLSHEAIDFLEKCFIPDPNKRATVTSLLSH 911 The following BLAST results are available for this feature:
BLAST of MAP3K-1 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99) Total hits: 5
BLAST of MAP3K-1 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99) Total hits: 5
BLAST of MAP3K-1 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99) Total hits: 5
BLAST of MAP3K-1 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99) Total hits: 5
BLAST of MAP3K-1 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99) Total hits: 5
BLAST of MAP3K-1 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99) Total hits: 5
BLAST of MAP3K-1 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt) Total hits: 5
BLAST of MAP3K-1 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL) Total hits: 5
BLAST of MAP3K-1 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99) Total hits: 5
BLAST of MAP3K-1 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99) Total hits: 5
BLAST of MAP3K-1 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46) Total hits: 5
BLAST of MAP3K-1 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46) Total hits: 5
BLAST of MAP3K-1 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99) Total hits: 5
BLAST of MAP3K-1 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST) Total hits: 5
Analyses
This transcript is derived from or has results from the following analyses Cross References
External references for this transcript
Sequences
The following sequences are available for this feature:
transcript sequence >SMED30013686 ID=SMED30013686|Name=MAP3K-1|organism=Schmidtea mediterranea sexual|type=transcript|length=4036bpback to top protein sequence of SMED30013686-orf-1 >SMED30013686-orf-1 ID=SMED30013686-orf-1|Name=SMED30013686-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=1214bp MSSNISKQNFSRSISVKPQKNAFEYGNDGELTTIYLNYPRELSRSTSTSKback to top Annotated Terms
The following terms have been associated with this transcript:
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
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