Acetyltransferase component of pyruvate dehydrogenase complex

Query:  232 RNYADYPSHKVITLPNLSPTMETGSVLSWGRKEGEAVAEGDLLAEIETDKATMSMDASDNGIMAKILVAAGTKDIPIGTPLCVIVENESDVAAFKDFKXXXXX-XXXXXXXXXXXXXXXXXXXXXXMESTKTXXXXXXXXXXXXXXGNRIFVSPYAKTLAAERNIDLATAGIAGSGPDGRIRASDLDQ---------ASSPLRTVGQQLSS-STASYTDIELSNMRKVIAQRLCISKQTIPHYYLTMDVRMNRVLEMRSKLNKKHEKSGIKISVNDFVIKASALACMRVLPCNSSWQDTFIRQYNQVDVSVAVATPNGLITPIVFSAHSKGLKEINNDVITLAAKARDNKLQPKEFQGGTFTVSNLGMYGISNFSAIINPPQACILAVGGSQNRLVANDKCDSGFSKATYMSVTLCCDHRVVDGAVGAQWLQEFRDNLEDPENM 1530
            R Y   P H+ + LP+LSPTM+ G++  W +KEG+ + EGDLLAEIETDKAT+  +  + G +AKILV  GT+D+P+GTPLC+IVE E+D++AF D++ +        +  P      A P  P P+  T +       A        R+FVSP AK LA E+ IDL    + G+GPDGRI   D+D           ++ +   G  ++   T  +TDI +SN+R+VIAQRL  SKQTIPHYYL++DV M  VL +R +LNK  E    KISVNDF+IKASALAC++V   NSSW DT IRQ + VDVSVAV+TP GLITPIVF+AH KG++ I NDV++LA KAR+ KLQP EFQGGTFT+SNLGM+GI NFSAIINPPQACILA+G S+++LV  D  + GF  A+ MSVTL CDHRVVDGAVGAQWL EFR  LE P  M
Sbjct:   42 RRYYSLPPHQKVPLPSLSPTMQAGTIARWEKKEGDKINEGDLLAEIETDKATIGFEVQEEGYLAKILVPEGTRDVPLGTPLCIIVEKEADISAFADYRPTEVTDLKPQVPPPTPPPVAAVPPTPQPLAPTPSAPCPATPAGPK----GRVFVSPLAKKLAVEKGIDLTQ--VKGTGPDGRITKKDIDSFVPSKVAPAPAAVVPPTGPGMAPVPTGVFTDIPISNIRRVIAQRLMQSKQTIPHYYLSIDVNMGEVLLVRKELNKILEGRS-KISVNDFIIKASALACLKVPEANSSWMDTVIRQNHVVDVSVAVSTPAGLITPIVFNAHIKGVETIANDVVSLATKAREGKLQPHEFQGGTFTISNLGMFGIKNFSAIINPPQACILAIGASEDKLVPADN-EKGFDVASMMSVTLSCDHRVVDGAVGAQWLAEFRKYLEKPITM 477          

Query:  241 ADYPSHKVITLPNLSPTMETGSVLSWGRKEGEAVAEGDLLAEIETDKATMSMDASDNGIMAKILVAAGTKDIPIGTPLCVIVENESDVAAFKDFKXXXXX-XXXXXXXXXXXXXXXXXXXXXXMESTKTXXXXXXXXXXXXXXGNRIFVSPYAKTLAAERNIDLATAGIAGSGPDGRIRASDLDQ---------ASSPLRTVGQQLSS-STASYTDIELSNMRKVIAQRLCISKQTIPHYYLTMDVRMNRVLEMRSKLNKKHEKSGIKISVNDFVIKASALACMRVLPCNSSWQDTFIRQYNQVDVSVAVATPNGLITPIVFSAHSKGLKEINNDVITLAAKARDNKLQPKEFQGGTFTVSNLGMYGISNFSAIINPPQACILAVGGSQNRLVANDKCDSGFSKATYMSVTLCCDHRVVDGAVGAQWLQEFRDNLEDPENM 1530
            + YP H  + LP LSPTM  G+V  W +K GE ++EGDLLAEIETDKAT+  +  + G +AKILV  GT+D+P+GTPLC+IVE E+D++AF D++ +        +  P      A P  P P+  T +       A        R+FVSP AK LA E+ IDL    + G+GPDGRI   D+D           ++ +   G  ++   T  +TDI +SN+R+VIAQRL  SKQTIPHYYL++DV M  VL +R +LNK  E    KISVNDF+IKASALAC++V   NSSW DT IRQ + VDVSVAV+TP GLITPIVF+AH KG++ I NDV++LA KAR+ KLQP EFQGGTFT+SNLGM+GI NFSAIINPPQACILA+G S+++LV  D  + GF  A+ MSVTL CDHRVVDGAVGAQWL EFR  LE P  M
Sbjct:  213 SSYPPHMQVLLPALSPTMTMGTVQRWEKKVGEKLSEGDLLAEIETDKATIGFEVQEEGYLAKILVPEGTRDVPLGTPLCIIVEKEADISAFADYRPTEVTDLKPQVPPPTPPPVAAVPPTPQPLAPTPSAPCPATPAGPK----GRVFVSPLAKKLAVEKGIDLTQ--VKGTGPDGRITKKDIDSFVPSKVAPAPAAVVPPTGPGMAPVPTGVFTDIPISNIRRVIAQRLMQSKQTIPHYYLSIDVNMGEVLLVRKELNKILEGRS-KISVNDFIIKASALACLKVPEANSSWMDTVIRQNHVVDVSVAVSTPAGLITPIVFNAHIKGVETIANDVVSLATKAREGKLQPHEFQGGTFTISNLGMFGIKNFSAIINPPQACILAIGASEDKLVPADN-EKGFDVASMMSVTLSCDHRVVDGAVGAQWLAEFRKYLEKPITM 645          

Query:  232 RNYADYPSHKVITLPNLSPTMETGSVLSWGRKEGEAVAEGDLLAEIETDKATMSMDASDNGIMAKILVAAGTKDIPIGTPLCVIVENESDVAAFKDF 522
            R Y   P H+ + LP+LSPTM+ G++  W +KEG+ + EGDL+AE+ETDKAT+  ++ +   MAKILVA GT+D+PIG  +C+ V    D+ AFK++
Sbjct:   83 RRYYSLPPHQKVPLPSLSPTMQAGTIARWEKKEGDKINEGDLIAEVETDKATVGFESLEECYMAKILVAEGTRDVPIGAIICITVGKPEDIEAFKNY 179          

Query:  670 NRIFVSPYAKTLAAERNIDLATAGIAGSGPDGRIRASDLDQ---------ASSPLRTVGQQLSS-STASYTDIELSNMRKVIAQRLCISKQTIPHYYLTMDVRMNRVLEMRSKLNKKHEKSGIKISVNDFVIKASALACMRVLPCNSSWQDTFIRQYNQVDVSVAVATPNGLITPIVFSAHSKGLKEINNDVITLAAKARDNKLQPKEFQGGTFTVSNLGMYGISNFSAIINPPQACILAVGGSQNRLVANDKCDSGFSKATYMSVTLCCDHRVVDGAVGAQWLQEFRDNLEDPENM 1530
             R+FVSP AK LA E+ IDL    + G+GPDGRI   D+D           ++ +   G  ++   T  +TDI +SN+R+VIAQRL  SKQTIPHYYL++DV M  VL +R +LNK  E    KISVNDF+IKASALAC++V   NSSW DT IRQ + VDVSVAV+TP GLITPIVF+AH KG++ I NDV++LA KAR+ KLQP EFQGGTFT+SNLGM+GI NFSAIINPPQACILA+G S+++LV  D  + GF  A+ MSVTL CDHRVVDGAVGAQWL EFR  LE P  M
Sbjct:  248 GRVFVSPLAKKLAVEKGIDLTQ--VKGTGPDGRITKKDIDSFVPSKVAPAPAAVVPPTGPGMAPVPTGVFTDIPISNIRRVIAQRLMQSKQTIPHYYLSIDVNMGEVLLVRKELNKILEGRS-KISVNDFIIKASALACLKVPEANSSWMDTVIRQNHVVDVSVAVSTPAGLITPIVFNAHIKGVETIANDVVSLATKAREGKLQPHEFQGGTFTISNLGMFGIKNFSAIINPPQACILAIGASEDKLVPADN-EKGFDVASMMSVTLSCDHRVVDGAVGAQWLAEFRKYLEKPITM 540          

Query:  232 RNYADYPSHKVITLPNLSPTMETGSVLSWGRKEGEAVAEGDLLAEIETDKATMSMDASDNGIMAKILVAAGTKDIPIGTPLCVIVENESDVAAFKDF 522
            R Y   P H+ + LP+LSPTM+ G++  W +KEG+ + EGDL+AE+ETDKAT+  ++ +   MAKILVA GT+D+PIG  +C+ V    D+ AFK++
Sbjct:   83 RRYYSLPPHQKVPLPSLSPTMQAGTIARWEKKEGDKINEGDLIAEVETDKATVGFESLEECYMAKILVAEGTRDVPIGAIICITVGKPEDIEAFKNY 179          

Query:  802 PLRTVGQQLSSSTASYTDIELSNMRKVIAQRLCISKQTIPHYYLTMDVRMNRVLEMRSKLNKKHEKSGIKISVNDFVIKASALACMRVLPCNSSWQDTFIRQYNQVDVSVAVATPNGLITPIVFSAHSKGLKEINNDVITLAAKARDNKLQPKEFQGGTFTVSNLGMYGISNFSAIINPPQACILAVGGSQN--RLVANDKCDSGFSKATYMSVTLCCDHRVVDGAVGAQWLQEFRDNLEDP 1521
            P+ T GQ   ++  ++T+I  SN+R+VIA+RL  SK T+PH Y T D  +  VL++R  L K      IK+SVNDF+IKA+A+   ++   N SW     +Q   +D+SVAVAT  GL+TPI+  A +KG++EI + V  L+ KARD KL P+E+QGG+F++SNLGM+GI  F+A+INPPQACILAVG  +   +L  +++ ++   +   ++VT+  D RVVD  +  ++L+ F+ NLE+P
Sbjct:  247 PVSTPGQ--PNAVGTFTEIPASNIRRVIAKRLTESKSTVPHAYATADCDLGAVLKVRQDLVKDD----IKVSVNDFIIKAAAVTLKQMPDVNVSWDGEGPKQLPFIDISVAVATDKGLLTPIIKDAAAKGIQEIADSVKALSKKARDGKLLPEEYQGGSFSISNLGMFGIDEFTAVINPPQACILAVGRFRPVLKLTEDEEGNAKLQQRQLITVTMSSDSRVVDDELATRFLKSFKANLENP 482          

Query:  226 ISRNYADYPSHKVIT--LPNLSPTMETGSVLSWGRKEGEAVAEGDLLAEIETDKATMSMDASDNGIMAKILVAAGTKDIPIGTPLCVIVENESD 501
            IS    D+P    I   +P+LSPTME G+++ W +KEGEAV+ GD L EIETDKA +++DASD+GI+AKI+V  G+K+I +G+ + +IVE   D
Sbjct:   29 ISSGAPDFPGGDPIKILMPSLSPTMEEGNIVKWLKKEGEAVSAGDALCEIETDKAVVTLDASDDGILAKIVVEEGSKNIRLGSLIGLIVEEGED 122          

Query:  802 PLRTVGQQLSSSTASYTDIELSNMRKVIAQRLCISKQTIPHYYLTMDVRMNRVLEMRSKLNKKHEKSGIKISVNDFVIKASALACMRVLPCNSSWQDTFIRQYNQVDVSVAVATPNGLITPIVFSAHSKGLKEINNDVITLAAKARDNKLQPKEFQGGTFTVSNLGMYGISNFSAIINPPQACILAVGGSQN--RLVANDKCDSGFSKATYMSVTLCCDHRVVDGAVGAQWLQEFRDNLEDP 1521
            P+ T GQ   ++  ++T+I  SN+R+VIA+RL  SK T+PH Y T D  +  VL++R  L K      IK+SVNDF+IKA+A+   ++   N SW     +Q   +D+SVAVAT  GL+TPI+  A +KG++EI + V  L+ KARD KL P+E+QGG+F++SNLGM+GI  F+A+INPPQACILAVG  +   +L  +++ ++   +   ++VT+  D RVVD  +  ++L+ F+ NLE+P
Sbjct:  262 PVSTPGQ--PNAVGTFTEIPASNIRRVIAKRLTESKSTVPHAYATADCDLGAVLKVRQDLVKDD----IKVSVNDFIIKAAAVTLKQMPDVNVSWDGEGPKQLPFIDISVAVATDKGLLTPIIKDAAAKGIQEIADSVKALSKKARDGKLLPEEYQGGSFSISNLGMFGIDEFTAVINPPQACILAVGRFRPVLKLTEDEEGNAKLQQRQLITVTMSSDSRVVDDELATRFLKSFKANLENP 497          

Query:  265 ITLPNLSPTMETGSVLSWGRKEGEAVAEGDLLAEIETDKATMSMDASDNGIMAKILVAAGTKDIPIGTPLCVIVENESD 501
            I +P+LSPTME G+++ W +KEGEAV+ GD L EIETDKA +++DASD+GI+AKI+V  G+K+I +G+ + +IVE   D
Sbjct:   59 ILMPSLSPTMEEGNIVKWLKKEGEAVSAGDALCEIETDKAVVTLDASDDGILAKIVVEEGSKNIRLGSLIGLIVEEGED 137          

Query:  214 ISQLISRNYADYPSHKVITLPNLSPTMETGSVLSWGRKEGEAVAEGDLLAEIETDKATMSMDASDNGIMAKILVAAGTKDIPIGTPLCVIVENESDVAAFKDFKXXXXXXXXXXXXXXXXXXXXXXXXXXXMESTKTXXXXXXXXXXXX---XXGNRIFVSPYAKTLAAERNIDLATAGIAGSGPDGRIRASDLDQASSPLRTVGQQLSSSTASYTDIELSNMRKVIAQRLCISKQTIPHYYLTMDVRMNRVLEMRSKLN----KKHEKSGIKISVNDFVIKASALACMRVLPCNSSWQDTFIRQYNQVDVSVAVATPNGLITPIVFSAHSKGLKEINNDVITLAAKARDNKLQPKEFQGGTFTVSNLGMYG-ISNFSAIINPPQACILAVGGSQNRLVANDKCDSGFSKATYMSVTLCCDHRVVDGAVGAQWLQEFRDNLEDPENM 1530
            I Q+   +  + P H  + LP LSPTME G+V+SW +KEG+ ++EGDLL EIETDKATM  +  + G +AKIL+  G+KD+PIG  LC+IV+NE+DVAAFKDFK   + +     +  K    A P               P V  S P   +   R+  SP+AK LAAE  +DL+    +G    GRI ASDL QA +   T     + S   YTDI LSNMRK IA+RL  SK TIPHYYLT +++++ +L++R KLN    K       KIS+NDF+IKASALAC RV   NS W D+FIR+ + VDVSVAV+TP GLITPI+F+AH+KGL  I ++++ LA +AR+ KLQP EFQGGTFTVSNLGM+G +S+F+AIINPPQ+CILA+GG+ ++LV ++    G+ K   M VTL CDHR VDGAVGA WL+ F++ LE P  M
Sbjct:   63 IKQVRLYSSGNLPKHNRVALPALSPTMELGTVVSWQKKEGDQLSEGDLLCEIETDKATMGFETPEEGYLAKILIQEGSKDVPIGKLLCIIVDNEADVAAFKDFKDDGASSGGSAPAAEKAPEPAKPAASSQPSPPAQMYQAPSVPKSAPIPHSSSGRVSASPFAKKLAAENGLDLSGVSGSGP--GGRILASDLSQAPAKGATSTTTQAVSGQDYTDIPLSNMRKTIAKRLTESKSTIPHYYLTSEIQLDTLLQVREKLNGLLAKGTSGQATKISINDFIIKASALACQRVPEANSYWMDSFIRENHHVDVSVAVSTPAGLITPIIFNAHAKGLATIASEIVELAQRAREGKLQPHEFQGGTFTVSNLGMFGSVSDFTAIINPPQSCILAIGGASDKLVPDEA--EGYKKIKTMKVTLSCDHRTVDGAVGAVWLRHFKEFLEKPHTM 505          

Query:  214 ISQLISRNYADYPSHKVITLPNLSPTMETGSVLSWGRKEGEAVAEGDLLAEIETDKATMSMDASDNGIMAKILVAAGTKDIPIGTPLCVIVENESDVAAFKDFKXXXXXXXXXXXXXXXXXXXXXXXXXXXMESTKTXXXXXXXXXXXX---XXGNRIFVSPYAKTLAAERNIDLATAGIAGSGPDGRIRASDLDQASSPLRTVGQQLSSSTASYTDIELSNMRKVIAQRLCISKQTIPHYYLTMDVRMNRVLEMRSKLN----KKHEKSGIKISVNDFVIKASALACMRVLPCNSSWQDTFIRQYNQVDVSVAVATPNGLITPIVFSAHSKGLKEINNDVITLAAKARDNKLQPKEFQGGTFTVSNLGMYG-ISNFSAIINPPQACILAVGGSQNRLVANDKCDSGFSKATYMSVTLCCDHRVVDGAVGAQWLQEFRDNLEDPENM 1530
            I Q+   +  + P H  + LP LSPTME G+V+SW +KEG+ ++EGDLL EIETDKATM  +  + G +AKIL+  G+KD+PIG  LC+IV+NE+DVAAFKDFK   + +     +  K    A P               P V  S P   +   R+  SP+AK LAAE  +DL+    +G    GRI ASDL QA +   T     + S   YTDI LSNMRK IA+RL  SK TIPHYYLT +++++ +L++R KLN    K       KIS+NDF+IKASALAC RV   NS W D+FIR+ + VDVSVAV+TP GLITPI+F+AH+KGL  I ++++ LA +AR+ KLQP EFQGGTFTVSNLGM+G +S+F+AIINPPQ+CILA+GG+ ++LV ++    G+ K   M VTL CDHR VDGAVGA WL+ F++ LE P  M
Sbjct:   63 IKQVRLYSSGNLPKHNRVALPALSPTMELGTVVSWQKKEGDQLSEGDLLCEIETDKATMGFETPEEGYLAKILIQEGSKDVPIGKLLCIIVDNEADVAAFKDFKDDGASSGGSAPAAEKAPEPAKPAASSQPSPPAQMYQAPSVPKSAPIPHSSSGRVSASPFAKKLAAENGLDLSGVSGSGP--GGRILASDLSQAPAKGATSTTTQAVSGQDYTDIPLSNMRKTIAKRLTESKSTIPHYYLTSEIQLDTLLQVREKLNGLLAKGTSGQATKISINDFIIKASALACQRVPEANSYWMDSFIRENHHVDVSVAVSTPAGLITPIIFNAHAKGLATIASEIVELAQRAREGKLQPHEFQGGTFTVSNLGMFGSVSDFTAIINPPQSCILAIGGASDKLVPDEA--EGYKKIKTMKVTLSCDHRTVDGAVGAVWLRHFKEFLEKPHTM 505          

Query:  835 STASYTDIELSNMRKVIAQRLCISKQTIPHYYLTMDVRMNRVLEMRSKLNKKHEKSGIKISVNDFVIKASALACMRVLPCNSSWQDTFIRQYNQVDVSVAVATPNGLITPIVFSAHSKGLKEINNDVITLAAKARDNKLQPKEFQGGTFTVSNLGMYG-ISNFSAIINPPQACILAVGGSQNRLVANDKCDSGFSKATYMSVTLCCDHRVVDGAVGAQWLQEFRDNLEDPE 1524
            S   + DI LSN+R  IA+RL  SKQ IPH Y  +DVR++ +L +R KL    +KSG  +S+NDF+IKA+ALA   V   N  W    I     VD+SVAVATP GLITPIV ++   G+  I++ V  L+  AR++KL+P++FQGG+FT+SNLGM+G ++NF+AIINPPQ  IL +GG+++ +V+    D        M V LC D R +      ++L  F ++L DPE
Sbjct:   96 SLRHHQDIPLSNIRATIAKRLTASKQQIPHEYQGVDVRIDDILALRQKL----KKSGTAVSLNDFIIKAAALALRSVPTVNVRWTPEGI-GLGSVDISVAVATPTGLITPIVENSDILGVLAISSKVKELSGLARESKLKPQQFQGGSFTISNLGMFGSVTNFTAIINPPQCAILTIGGTRSEVVS---VDGQLETQKLMGVNLCFDGRAISEECAKRFLLHFSESLSDPE 318          

Query:  856 IELSNMRKVIAQRLCISKQTIPHYYLTMDVRMNRVLEMRSKLNKKH-EKSGIKISVNDFVIKASALACMRVLPCNSSWQDTFIRQYNQVDVSVAVATPNGLITPIVFSAHSKGLKEINNDVITLAAKARDNKLQPKEFQGGTFTVSNLGMYGISNFSAIINPPQACILAVGGSQNRLV-ANDKCDSGFSKATYMSVTLCCDHRVVDGAVGAQWLQEFRDNLEDPENM 1530
            ++ + MR  IAQRL  ++ T        ++ M+ ++EMR    K    K G+K+ +    ++A+A A       N+   +  I   + VD+SVAVATP GL+ P++ +  S    +I  ++  L  KARD KL  ++ +GGTFT+SN G++G    + IINPPQ+ IL + G  +R+V  N K +        M + L  DHR++DG     +L++ +  +EDP  M
Sbjct:  237 VKANRMRMRIAQRLKDAQNTYAMLTTFNEIDMSSLIEMRKTYQKDFVAKHGVKLGMMSPFVRAAAYALQESPVVNAVLDENEIVYRHFVDISVAVATPKGLVVPVLRNVESMNYAQIELELANLGVKARDGKLAVEDMEGGTFTISNGGVFGSMFGTPIINPPQSAILGMHGVFDRVVPVNGKPEI----RPIMQIALTYDHRLIDGREAVTFLKKIKTAVEDPRIM 459          

Query:  307 VLSWGRKEGEAVAEGDLLAEIETDKATMSMDASDNGIMAKILVAAGTKDIPIGTPLCVIVENESDVAAFKDFKXXXXXXXXXXXXXXXXXXXXXXXXXXXMESTKTXXXXXXXXXXXXXXGNRIFVSPYAKTLAAERNIDLATAGIAGSGPDGRIRASDL-----------DQASSPLRTVGQQLSSSTASYTDIE----------LSNMRKVIAQRLCISKQTIPHYYLTMDVRMNRVLEMRSKLNKKHEKSGIKISVNDFVIKASALACMRVLPCNSSWQDTFIRQYNQV--DVSVAVATPNGLITPIVFSAHSKGLKEINNDVITLAAKARDNKLQPKEFQGGTFTVSNLGMYGISNFSAIINPPQACILAVGGSQNRLVANDKCDSGFSKATYMSVTLCCDHRVVDGAVGAQWLQEFRDNLEDPENM 1530
            V  W  KEG+ +++ D + E+++DKA +++    +GI+ K+          +G  L + VE E +V   +  K  ++ +                       S + P S+ P A        ++  +P  + +A E  I LA   + G+G DGR+   D+              S+ +RT  Q    S+ SY  ++             M K + + L      IPH+    ++ ++ +++ R++L +  ++  IK+S   F IKA++LA +     NS+  +      ++   ++ +A+ TP GL+ P + +   + + EI  ++  L    +  +++ ++   GTF++SN+G  G +  S ++ PPQ  I A+G  + +L   DK D+       M V+ C DHRVVDGA  A++   ++  LE P  M
Sbjct:   47 VKEWYVKEGDTISQFDKVCEVQSDKAAVTISCRYDGIVKKLYHEVDGM-ARVGQAL-IDVEIEGNVEEPEQPKKEAASS-----------------------SPEAPKSSAPKAPESAHSEGKVLATPAVRRIAIENKIKLAE--VRGTGKDGRVLKEDVLKFLGQVPADHTSGSTNIRTTHQAPQPSSKSYEPLKEDVAVPIRGYTRAMVKTMTEAL-----KIPHFGYNDEINVDSLVKYRAELKEFAKERHIKLSYMPFFIKAASLALLEYPSLNSTTDEKMENVIHKASHNICLAMDTPGGLVVPNIKNCEQRSIFEIAQELNRLLEAGKKQQIKREDLIDGTFSLSNIGNIGGTYASPVVFPPQVAIGAIGKIE-KLPRFDKHDNVIP-VNIMKVSWCADHRVVDGATMARFSNRWKFYLEHPSAM 443          

Query:  112 FYNSSKIESFQHNTPLNRKIHFIHYSRKFLVDNRISQLISRNYADYPSHKVITLPNLSPTMETGSVLSWGRKEGEAVAEGDLLAEIETDKATMSMDASDNGIMAKILVAAGTKDIPIGTPLCVIVENESDVAAFKDFK-----XXXXXXXXXXXXXXXXXXXXXXXXXXXMESTKTXXXXXXXXXXXXXXGNRIFVSPYAKTLAAERNIDLATAGIAGSGPDGRIRASDLDQASSPLRTVGQQLSSSTAS----YTDIELSNMRKVIAQRLCISKQTIPHYYLTMDVRMNRVLEMRSKLNKKHEKSGIKISVNDFVIKASALACMRVLPCNSSWQDTFIRQYNQVDVSVAVATPNGLITPIVFSAHSKGLKEINNDVITLAAKARDNKLQPKEFQGGTFTVSNLGMYGISNFSAIINPPQACILAVGGSQNRLVANDKCDSGFSKATYMSVTLCCDHRVVDGAVGAQWLQEFRDNLEDPENM 1530
              NS K++S +  + LN     + +S  F          +R YA+ P H  + LP LSPTME GS++SW +KEG+ + EGDLL EIETDKATM  +  + G +AKIL+  GTKD+P+G  LC+IV ++  VAAF +FK      + +  ++             P PPP            P AA   A   R++ SP AK LA  + + L   G   SG  G I++ DL    +  +      + +  +    Y DI ++NMR VIA+RL  SK  +PHYY+T+  +++++L+ R+K+NKK+EK G ++SVNDF+IKA A+A ++V   NS+W DT IR+Y+ VDVSVAV+T  GLITPIVF+A  KG+ EI+ DV  LAAKARDNKLQP EFQGGT +VSNLGM+G++ F+A+INPPQ+CILA+G +  +LVA+     GF +   ++VTL  DHRVVDGAV A+WLQ FRD +EDP NM
Sbjct:   44 LINSRKLQSIR--SKLNTSQSPVTWSYNF----------ARAYANLPEHIRVPLPALSPTMERGSIVSWEKKEGDKLNEGDLLCEIETDKATMGFETPEEGFLAKILIQGGTKDVPVGQLLCIIVPDQGSVAAFANFKDDGAAAAPAAPAAAPAPAPAAAAAPPPPPPPAAAPAAAAPPPAPAAAPAAAGTGRVYASPMAKRLAEAQQLRLQGKG---SGVHGSIKSGDLAGQKAAAKPAAAAPAKAPRAAGARYEDIPVTNMRAVIAKRLLESKTQLPHYYVTVQCQVDKLLKFRAKVNKKYEKQGARVSVNDFIIKAVAIASLKVPEANSAWMDTVIRKYDDVDVSVAVSTDKGLITPIVFNADRKGVLEISKDVKALAAKARDNKLQPHEFQGGTISVSNLGMFGVNQFAAVINPPQSCILAIGTTTKQLVADPDSLKGFKEVNMLTVTLSADHRVVDGAVAARWLQHFRDYMEDPSNM 510          

Query:  112 FYNSSKIESFQHNTPLNRKIHFIHYSRKFLVDNRISQLISRNYADYPSHKVITLPNLSPTMETGSVLSWGRKEGEAVAEGDLLAEIETDKATMSMDASDNGIMAKILVAAGTKDIPIGTPLCVIVENESDVAAFKDFK-----XXXXXXXXXXXXXXXXXXXXXXXXXXXMESTKTXXXXXXXXXXXXXXGNRIFVSPYAKTLAAERNIDLATAGIAGSGPDGRIRASDLDQASSPLRTVGQQLSSSTAS----YTDIELSNMRKVIAQRLCISKQTIPHYYLTMDVRMNRVLEMRSKLNKKHEKSGIKISVNDFVIKASALACMRVLPCNSSWQDTFIRQYNQVDVSVAVATPNGLITPIVFSAHSKGLKEINNDVITLAAKARDNKLQPKEFQGGTFTVSNLGMYGISNFSAIINPPQACILAVGGSQNRLVANDKCDSGFSKATYMSVTLCCDHRVVDGAVGAQWLQEFRDNLEDPENM 1530
              NS K++S +  + LN     + +S  F          +R YA+ P H  + LP LSPTME GS++SW +KEG+ + EGDLL EIETDKATM  +  + G +AKIL+  GTKD+P+G  LC+IV ++  VAAF +FK      + +  ++             P PPP            P AA   A   R++ SP AK LA  + + L   G   SG  G I++ DL    +  +      + +  +    Y DI ++NMR VIA+RL  SK  +PHYY+T+  +++++L+ R+K+NKK+EK G ++SVNDF+IKA A+A ++V   NS+W DT IR+Y+ VDVSVAV+T  GLITPIVF+A  KG+ EI+ DV  LAAKARDNKLQP EFQGGT +VSNLGM+G++ F+A+INPPQ+CILA+G +  +LVA+     GF +   ++VTL  DHRVVDGAV A+WLQ FRD +EDP NM
Sbjct:   44 LINSRKLQSIR--SKLNTSQSPVTWSYNF----------ARAYANLPEHIRVPLPALSPTMERGSIVSWEKKEGDKLNEGDLLCEIETDKATMGFETPEEGFLAKILIQGGTKDVPVGQLLCIIVPDQGSVAAFANFKDDGAAAAPAAPAAAPAPAPAAAAAPPPPPPPAAAPAAAAPPPAPAAAPAAAGTGRVYASPMAKRLAEAQQLRLQGKG---SGVHGSIKSGDLAGQKAAAKPAAAAPAKAPRAAGARYEDIPVTNMRAVIAKRLLESKTQLPHYYVTVQCQVDKLLKFRAKVNKKYEKQGARVSVNDFIIKAVAIASLKVPEANSAWMDTVIRKYDDVDVSVAVSTDKGLITPIVFNADRKGVLEISKDVKALAAKARDNKLQPHEFQGGTISVSNLGMFGVNQFAAVINPPQSCILAIGTTTKQLVADPDSLKGFKEVNMLTVTLSADHRVVDGAVAARWLQHFRDYMEDPSNM 510          

Query:  292 METGSVLSWGRKEGEAVAEGDLLAEIETDKATMSMDASDNGIMAKILVAAGTKDIPIGTPLCVIVENESDV---AAFK-DFKXXXXXXXXXXXXXXXXXXXXXXXXXXXMESTKTXXXXXXXXXXXXXXG-NRIFVSPYAKTLAAERNIDLATAGIAGSGPDGRIRASDLDQASSPLRTVGQQLSSSTAS----YTDIELSNMRKVIAQRLCISKQTIPHYYLTMDVRMNRVLEMRSKLNKKHEKSGIKISVNDFVIKASALACMRVLPCNSSWQDTFIRQYNQVDVSVAVATPNGLITPIVFSAHSKGLKEINNDVITLAAKARDNKLQPKEFQGGTFTVSNLGMYGISNFSAIINPPQACILAVGGSQNRLVANDKCDSGFSKATYMSVTLCCDHRVVDGAVGAQWLQEFRDNLEDPENM 1530
            ME GS++SW +KEG+ + EGDLL EIETDKATM  +  + G +AKIL+  GTKD+P+G  LC+IV ++  V   A FK D   ++  A +   +PA     A P PPPP  +       P  AA+  A G  R++ SP AK LA  + + L   G   SG  G I++ DL    +  +      + +  +    Y DI ++NMR VIA+RL  SK  +PHYY+T+  +++++L+ R+K+NKK+EK G ++SVNDF+IKA A+A ++V   NS+W DT IR+Y+ VDVSVAV+T  GLITPIVF+A  KG+ EI+ DV  LAAKARDNKLQP EFQGGT +VSNLGM+G++ F+A+INPPQ+CILA+G +  +LVA+     GF +   ++VTL  DHRVVDGAV A+WLQ FRD +EDP NM
Sbjct:    1 MERGSIVSWEKKEGDKLNEGDLLCEIETDKATMGFETPEEGFLAKILIQGGTKDVPVGQLLCIIVPDQGSVAAFANFKDDGAAAAPAAPAAAPAPAPAAAAAPPPPPPPAAAPAAAAPPPAPAAAPAAAGTGRVYASPMAKRLAEAQQLRLQGKG---SGVHGSIKSGDLAGQKAAAKPAAAAPAKAPRAAGARYEDIPVTNMRAVIAKRLLESKTQLPHYYVTVQCQVDKLLKFRAKVNKKYEKQGARVSVNDFIIKAVAIASLKVPEANSAWMDTVIRKYDDVDVSVAVSTDKGLITPIVFNADRKGVLEISKDVKALAAKARDNKLQPHEFQGGTISVSNLGMFGVNQFAAVINPPQSCILAIGTTTKQLVADPDSLKGFKEVNMLTVTLSADHRVVDGAVAARWLQHFRDYMEDPSNM 419          

Query:  748 GSGPDGRIRASDLDQASSPLRTVGQQLSSSTAS----YTDIELSNMRKVIAQRLCISKQTIPHYYLTMDVRMNRVLEMRSKLNKKHEKSGIKISVNDFVIKASALACMRVLPCNSSWQDTFIRQYNQVDVSVAVATPNGLITPIVFSAHSKGLKEINNDVITLAAKARDNKLQPKEFQGGTFTVSNLGMYGISNFSAIINPPQACILAVGGSQNRLVANDKCDSGFSKATYMSVTLCCDHRVVDGAVGAQWLQEFRDNLEDPENM 1530
            GSG  G I++ DL    +  +      + +  +    Y DI ++NMR VIA+RL  SK  +PHYY+T+  +++++L+ R+K+NKK+EK G ++SVNDF+IKA A+A ++V   NS+W DT IR+Y+ VDVSVAV+T  GLITPIVF+A  KG+ EI+ DV  LAAKARDNKLQP EFQGGT +VSNLGM+G++ F+A+INPPQ+CILA+G +  +LVA+     GF +   ++VTL  DHRVVDGAV A+WLQ FRD +EDP NM
Sbjct:  223 GSGVHGSIKSGDLAGQKAAAKPAAAAPAKAPRAAGARYEDIPVTNMRAVIAKRLLESKTQLPHYYVTVQCQVDKLLKFRAKVNKKYEKQGARVSVNDFIIKAVAIASLKVPEANSAWMDTVIRKYDDVDVSVAVSTDKGLITPIVFNADRKGVLEISKDVKALAAKARDNKLQPHEFQGGTISVSNLGMFGVNQFAAVINPPQSCILAIGTTTKQLVADPDSLKGFKEVNMLTVTLSADHRVVDGAVAARWLQHFRDYMEDPSNM 487          

Query:  112 FYNSSKIESFQHNTPLNRKIHFIHYSRKFLVDNRISQLISRNYADYPSHKVITLPNLSPTMETGSVLSWGRKEGEAVAEGDLLAEIETDKATMSMDASDNGIMAKILVAAGTKDIPIGTPLCVIVENESDVAAFKDFK 525
              NS K++S +  + LN     + +S  F          +R YA+ P H  + LP LSPTME GS++SW +KEG+ + EGDLL EIETDKATM  +  + G +AKIL+  GTKD+P+G  LC+IV ++  VAAF +FK
Sbjct:   44 LINSRKLQSIR--SKLNTSQSPVTWSYNF----------ARAYANLPEHIRVPLPALSPTMERGSIVSWEKKEGDKLNEGDLLCEIETDKATMGFETPEEGFLAKILIQGGTKDVPVGQLLCIIVPDQGSVAAFANFK 169          

Query:  847 YTDIELSNMRKVIAQRLCISKQTIPHYYLTMDVRMNRVLEMRSKLNKKHEKSGIKISVNDFVIKASALACMRVLPCNSSWQDTFIRQYNQVDVSVAVATPNGLITPIVFSAHSKGLKEINNDVITLAAKARDNKLQPKEFQGGTFTVSNLGMYGISNFSAIINPPQACILAVGGSQNRLVANDKCDSGFSKATYMSVTLCCDHRVVDGAVGAQWLQEFRDNLEDPENM 1530
            Y DI ++NMR VIA+RL  SK  +PHYY+T+  +++++L+ R+K+NKK+EK G ++SVNDF+IKA A+A ++V   NS+W DT IR+Y+ VDVSVAV+T  GLITPIVF+A  KG+ EI+ DV  LAAKARDNKLQP EFQGGT +VSNLGM+G++ F+A+INPPQ+CILA+G +  +LVA+     GF +   ++VTL  DHRVVDGAV A+WLQ FRD +EDP NM
Sbjct:  244 YEDIPVTNMRAVIAKRLLESKTQLPHYYVTVQCQVDKLLKFRAKVNKKYEKQGARVSVNDFIIKAVAIASLKVPEANSAWMDTVIRKYDDVDVSVAVSTDKGLITPIVFNADRKGVLEISKDVKALAAKARDNKLQPHEFQGGTISVSNLGMFGVNQFAAVINPPQSCILAIGTTTKQLVADPDSLKGFKEVNMLTVTLSADHRVVDGAVAARWLQHFRDYMEDPSNM 471          

Query:  112 FYNSSKIESFQHNTPLNRKIHFIHYSRKFLVDNRISQLISRNYADYPSHKVITLPNLSPTMETGSVLSWGRKEGEAVAEGDLLAEIETDKATMSMDASDNGIMAKILVAAGTKDIPIGTPLCVIVENESDVAAFKDFK 525
              NS K++S +  + LN     + +S  F          +R YA+ P H  + LP LSPTME GS++SW +KEG+ + EGDLL EIETDKATM  +  + G +AKIL+  GTKD+P+G  LC+IV ++  VAAF +FK
Sbjct:   44 LINSRKLQSIR--SKLNTSQSPVTWSYNF----------ARAYANLPEHIRVPLPALSPTMERGSIVSWEKKEGDKLNEGDLLCEIETDKATMGFETPEEGFLAKILIQGGTKDVPVGQLLCIIVPDQGSVAAFANFK 169          

Query:  241 ADYPSHKVITLPNLSPTMETGSVLSWGRKEGEAVAEGDLLAEIETDKATMSMDASDNGIMAKILVAAGTKDIPIGTPLCVIVENESDVAAFKDFKXXXXXXXXXXXXXXXXXXXXXXXXXXXMESTKTXXXXXXXXXXXXXXGNRIFVSPYAKTLAAERNIDLATAGIAGSGPDGRIRASDLDQ----------------ASSPLRTVGQQLSSSTASYTDIELSNMRKVIAQRLCISKQTIPHYYLTMDVRMNRVLEMRSKLNKKHEKSGIKISVNDFVIKASALACMRVLPCNSSWQDTFIRQYNQVDVSVAVATPNGLITPIVFSAHSKGLKEINNDVITLAAKARDNKLQPKEFQGGTFTVSNLGMYGISNFSAIINPPQACILAVGGSQNRLVANDKCDSGFSKATYMSVTLCCDHRVVDGAVGAQWLQEFRDNLEDPENM 1530
            + YP H  + LP LSPTM  G+V  W +K GE ++EGDLLAEIETDKAT+  +  + G +AKI+++ GT+D+P+GTPLC+IVE ESD++AF D+       +    SP       A  PP    +   P      AA   A   R+F SP AK LAAE+ +D+    + G+GPDGR+   D+D                  +          +  T ++TD+ +SN+RKVIAQRL  SKQTIPHYYL++DV M++VLE+R +LN + +   IK+SVNDF+IKASALAC++V   NSSW DT IRQ + VDVSVAV+TP GLITPIVF+AH KGL  I+ DV  LAAKARD KLQP EFQGGTFT+SNLGMYGI +FSAIINPPQACILAVGGS+ RL+  D  + GF  A  MSVTL CDHRVVDGAVGAQWL EFR  LE P  M
Sbjct:  213 SSYPPHMKVLLPALSPTMTMGTVQRWEKKVGEKLSEGDLLAEIETDKATIGFEVQEEGYLAKIMISEGTRDVPLGTPLCIIVEKESDISAFADY-----VETGVAASPPPAPTPVATPPPAAAPAAPIPAPAAAPAAPAAARKGRVFASPLAKKLAAEKGVDITQ--VTGTGPDGRVTKKDIDSFVPPKLAPAAAAAPSAPTPSPPAAPAYAAVPTGTFTDVPISNIRKVIAQRLMQSKQTIPHYYLSIDVNMDQVLELRKELNAEVKAENIKLSVNDFIIKASALACLKVPEANSSWMDTVIRQNHVVDVSVAVSTPVGLITPIVFNAHIKGLANISKDVSALAAKARDGKLQPHEFQGGTFTISNLGMYGIKHFSAIINPPQACILAVGGSEKRLLPADN-EKGFDVANMMSVTLSCDHRVVDGAVGAQWLAEFRKFLEKPFTM 650          

Query:  250 PSHKVITLPNLSPTMETGSVLSWGRKEGEAVAEGDLLAEIETDKATMSMDASDNGIMAKILVAAGTKDIPIGTPLCVIVENESDVAAFKDF 522
            P H+ + LP LSPTM+ G++  W +KEG+ + EGDL+AE+ETDKAT+  +  +   +AKILVA GT+D+PIG  +C+ V+    +++FKDF
Sbjct:   90 PPHQKVELPALSPTMQMGTIARWEKKEGDKINEGDLIAEVETDKATVGFEMLEECYLAKILVAEGTRDVPIGAVICITVDKPELISSFKDF 180          

Query:  844 SYTDIELSNMRKVIAQRLCISKQTIPHYYLTMDVRMNRVLEMRSKLNKKHEKSGIKISVNDFVIKASALACMRVLPC-NSSWQDTFIRQYNQVDVSVAVATPNGLITPIVFSAHSKGLKEINNDVITLAAKARDNKLQPKEFQGGTFTVSNLGMYGISNFSAIINPPQACILAVGGSQNRLVANDKCDSGFSKATYMSVTLCCDHRVVDGAVGAQWLQEFRDNLEDPENM 1530
            ++T+I  S++R++IAQRL  SK TIPH Y  +   ++ V+ +R +L +++    IK+SVNDF+IKA+A++ +R LP  N SW     +    + +S+AVAT  GLITPI+  A  KGL+EI++    LA KARD KL P+E+QGG+F+VSNLGM+GIS FSA+INPPQACILAVGGS+  L  +   +        ++VTL  D R+VD  + +++L+ FR NLE PE M
Sbjct:  270 TFTEIPASSVRRIIAQRLTQSKTTIPHTYACIHCDISGVMRVRKRLAEEN----IKVSVNDFIIKAAAVS-LRELPAVNVSWSADGPQPLGFIHISMAVATDRGLITPIIRDAADKGLQEISSTAKALAQKARDGKLLPEEYQGGSFSVSNLGMFGISEFSAVINPPQACILAVGGSRTELSLS--AEDTLQTQHTLTVTLSSDARLVDDELASRFLETFRSNLERPERM 492          

Query:  265 ITLPNLSPTMETGSVLSWGRKEGEAVAEGDLLAEIETDKATMSMDASDNGIMAKILVAAGTKDIPIGTPLCVIVENESD 501
            + +P LSPTME G+++ W +KEGE VA GD L EIETDKA + M+++++G++A+ILV  G++ + +GT + ++V    D
Sbjct:   65 VQMPALSPTMEEGNIVKWLKKEGEDVAAGDALCEIETDKAVVVMESNEDGVLARILVQEGSRGVRLGTLIALMVSEGED 143          

Query:  841 ASYTDIELSNMRKVIAQRLCISKQTIPHYYLTMDVRMNRVLEMRSKLNKKHEKSGIKISVNDFVIKASALACMRVLPC-NSSWQDTFIRQYNQVDVSVAVATPNGLITPIVFSAHSKGLKEINNDVITLAAKARDNKLQPKEFQGGTFTVSNLGMYGISNFSAIINPPQACILAVGGSQNRLVANDKCDSGFSKATYMSVTLCCDHRVVDGAVGAQWLQEFRDNLEDPENM 1530
             ++T+I  S++R++IAQRL  SK TIPH Y  +   ++ V+ +R +L +++    IK+SVNDF+IKA+A++ +R LP  N SW     +    + +S+AVAT  GLITPI+  A  KGL+EI++    LA KARD KL P+E+QGG+F+VSNLGM+GIS FSA+INPPQACILAVGGS+  L  +   +        ++VTL  D R+VD  + +++L+ FR NLE PE M
Sbjct:  262 GTFTEIPASSVRRIIAQRLTQSKTTIPHTYACIHCDISGVMRVRKRLAEEN----IKVSVNDFIIKAAAVS-LRELPAVNVSWSADGPQPLGFIHISMAVATDRGLITPIIRDAADKGLQEISSTAKALAQKARDGKLLPEEYQGGSFSVSNLGMFGISEFSAVINPPQACILAVGGSRTELSLS--AEDTLQTQHTLTVTLSSDARLVDDELASRFLETFRSNLERPERM 485          

Query:  265 ITLPNLSPTMETGSVLSWGRKEGEAVAEGDLLAEIETDKATMSMDASDNGIMAKILVAAGTKDIPIGTPLCVIVENESD 501
            + +P LSPTME G+++ W +KEGE VA GD L EIETDKA + M+++++G++A+ILV  G++ + +GT + ++V    D
Sbjct:   64 VQMPALSPTMEEGNIVKWLKKEGEDVAAGDALCEIETDKAVVVMESNEDGVLARILVQEGSRGVRLGTLIALMVSEGED 142          

Query:  856 IELSNMRKVIAQRLCISKQTIPHYYLTMDVRMNRVLEMRSKLNKKH-EKSGIKISVNDFVIKASALACMRVLPCNSSWQDTF--IRQYNQVDVSVAVATPNGLITPIVFSAHSKGLKEINNDVITLAAKARDNKLQPKEFQGGTFTVSNLGMYGISNFSAIINPPQACILAVGGSQNRLVANDKCDSGFSKATYMSVTLCCDHRVVDGAVGAQWLQEFRDNLEDP 1521
            ++++ MR  IAQRL  ++ T        +V M+ + EMR+       +K GIK+      +KA+A A       N+   DT   I   + VD+SVAVATP GL+ P++         +I   +  L  KAR N+L  ++  GGTFT+SN G++G    + IINPPQ+ IL + G  +R VA             M V L  DHR++DG     +L++ +  +EDP
Sbjct:  230 VKMNRMRLRIAQRLKEAQNTCAMLTTFNEVDMSNITEMRTHYKDAFLKKHGIKLGFMSAFVKAAAYALTDQPAVNAVIDDTTKEIVYRDYVDISVAVATPKGLVVPVIRGVEGMNFADIEKTINELGEKARKNELAVEDMDGGTFTISNGGVFGSMFGTPIINPPQSAILGMHGIFDRPVA---IAGKVEVRPMMYVALTYDHRLIDGREAVTFLRKIKSVVEDP 451          

Query:  850 TDIELSNMRKVIAQRLCISKQTIPHYYLTMDVRMNRVLEMRSKLNKKH-EKSGIKISVNDFVIKASALACMRVLPCNSSWQDTF--IRQYNQVDVSVAVATPNGLITPIVFSAHSKGLKEINNDVITLAAKARDNKLQPKEFQGGTFTVSNLGMYGISNFSAIINPPQACILAVGGSQNRLVANDKCDSGFSKATYMSVTLCCDHRVVDGAVGAQWLQEFRDNLEDP 1521
            + ++++ MR  IAQRL  ++ T        +V M+ + EMR+       +K  IK+      +KA+A A       N+   DT   I   + VD+SVAVATP GL+ P++         +I   +  L  KAR N+L  ++  GGTFT+SN G++G    + IINPPQ+ IL + G  +R VA             M V L  DHR++DG     +L++ +  +EDP
Sbjct:  206 SQVKMNRMRLRIAQRLKEAQNTCAMLTTFNEVDMSNITEMRTHYKDAFLKKHSIKLGFMSAFVKAAAYALTDQPAVNAVIDDTTKEIVYRDYVDISVAVATPKGLVVPVIRGVEGMNFADIEKTINELGEKARKNELAVEDMDGGTFTISNGGVFGSMFGTPIINPPQSAILGMHGIFDRPVA---IAGKVEVRPMMYVALTYDHRLIDGREAVTFLRKIKSVVEDP 429          

Query:  247 YPSHKVITLPNLSPTMETGSVLSWGRKEGEAVAEGDLLAEIETDKATMSMDASDNGIMAKILVAAGTKDIPIGTPLCVIVENESDVAAFKDFKXXXXXXXXXXXXXXXXXXXXXXXXXXXMESTKTXXXXXXXXXXXXXXGNRIFVSPYAKTLAAERNIDLATAGIAGSGPDGRIRASDLDQ--------------ASSPLRTVGQQLSSSTASYTDIELSNMRKVIAQRLCISKQTIPHYYLTMDVRMNRVLEMRSKLNKKHEKSGIKISVNDFVIKASALACMRVLPCNSSWQDTFIRQYNQVDVSVAVATPNGLITPIVFSAHSKGLKEINNDVITLAAKARDNKLQPKEFQGGTFTVSNLGMYGISNFSAIINPPQACILAVGGSQNRLVANDKCDSGFSKATYMSVTLCCDHRVVDGAVGAQWLQEFRDNLEDPENM 1530
            YP+H  I LP LSPTM  G+V  W +K GE ++EGDLLAEIETDKAT+  +  + G +AKIL+  GT+D+P+GTPLC+IVE ESD+ +F+D+K  +   ++    P    P  AP P     + K                 R+F+SP A+ LA+E+ ID+    + GSGP+GRI   D+D               A +         +  +  +TD+ +SN+R+VIAQRL  SKQTIPHYYL++D+ M  ++++R +LN+  +   IK+SVNDF+IKASALAC++V   NSSW DT IRQ++ VDVSVAV+TP GLITPIVF+AH+KGL  I+ DV++LA +AR+ KL+P EFQGGTFTVSNLGMYGI NFSAIINPPQACILAVGGS+NRL+  D  + GF  A+ MSVTL CDHRVVDGAVGAQWL EF+  LE P  M
Sbjct:  138 YPNHMKICLPALSPTMTMGTVQKWEKKVGEKLSEGDLLAEIETDKATIGFEVPEEGYLAKILIEEGTRDVPLGTPLCIIVEKESDIGSFEDYKELTGVTAAPPPVPQVAVPPPAPTPSTAPSAPK----------------GRVFISPLARKLASEKGIDIKQ--VKGSGPEGRITKKDIDSFVPPKAAPVPAAAPAPAVAVPSPAVAAVPSGVFTDVPISNIRRVIAQRLMQSKQTIPHYYLSIDINMGEIVQLRKELNEVTKADNIKLSVNDFIIKASALACLKVPEANSSWLDTVIRQHHVVDVSVAVSTPVGLITPIVFNAHTKGLATISKDVLSLATRAREGKLKPHEFQGGTFTVSNLGMYGIKNFSAIINPPQACILAVGGSENRLIPADN-EKGFDVASMMSVTLSCDHRVVDGAVGAQWLAEFKKFLEKPTTM 560          

Query:  280 LSPTMETGSVLSWGRKEGEAVAEGDLLAEIETDKATMSMDASDNGIMAKILVAAGTKDIPIGTPLCVIVENESDVAAFKDF 522
            LSPTM+ G++  W +KEG+ + EGDL+AE+ETDKAT+  ++ + G MAKILVA GT+D+PIG+ +C+ V+    + AFK++
Sbjct:   26 LSPTMQMGTIARWEKKEGDKINEGDLIAEVETDKATVGFESLEEGYMAKILVAEGTRDVPIGSVICITVDKPEFIDAFKNY 106          

Query:  247 YPSHKVITLPNLSPTMETGSVLSWGRKEGEAVAEGDLLAEIETDKATMSMDASDNGIMAKILVAAGTKDIPIGTPLCVIVENESDVAAFKDFKXXXXXXXXXXXXXXXXXXXXXXXXXXXMESTKTXXXXXXXXXXXXXXGNRIFVSPYAKTLAAERNIDLATAGIAGSGPDGRIRASDLDQ--------------ASSPLRTVGQQLSSSTASYTDIELSNMRKVIAQRLCISKQTIPHYYLTMDVRMNRVLEMRSKLNKKHEKSGIKISVNDFVIKASALACMRVLPCNSSWQDTFIRQYNQVDVSVAVATPNGLITPIVFSAHSKGLKEINNDVITLAAKARDNKLQPKEFQGGTFTVSNLGMYGISNFSAIINPPQACILAVGGSQNRLVANDKCDSGFSKATYMSVTLCCDHRVVDGAVGAQWLQEFRDNLEDPENM 1530
            YP+H  I LP LSPTM  G+V  W +K GE ++EGDLLAEIETDKAT+  +  + G +AKIL+  GT+D+P+GTPLC+IVE ESD+ +F+D+K  +  A       A T   A P  P        P  +   +A       R+F+SP A+ LA+E+ ID+    + GSGP+GRI   D+D               A +         +  +  +TD+ +SN+R+VIAQRL  SKQTIPHYYL++D+ M  ++++R +LN+  +   IK+SVNDF+IKASALAC++V   NSSW DT IRQ++ VDVSVAV+TP GLITPIVF+AH+KGL  I+ DV++LA +AR+ KL+P EFQGGTFTVSNLGMYGI NFSAIINPPQACILAVGGS+NRL+  D  + GF  A+ MSVTL CDHRVVDGAVGAQWL EF+  LE P  M
Sbjct:  192 YPNHMKICLPALSPTMTMGTVQKWEKKVGEKLSEGDLLAEIETDKATIGFEVPEEGYLAKILIEEGTRDVPLGTPLCIIVEKESDIGSFEDYKELTGVADIKPQPAAPTPTAAPPPVPQVAVPPPAPTPSTAPSAPK----GRVFISPLARKLASEKGIDIKQ--VKGSGPEGRITKKDIDSFVPPKAAPVPAAAPAPAVAVPSPAVAAVPSGVFTDVPISNIRRVIAQRLMQSKQTIPHYYLSIDINMGEIVQLRKELNEVTKADNIKLSVNDFIIKASALACLKVPEANSSWLDTVIRQHHVVDVSVAVSTPVGLITPIVFNAHTKGLATISKDVLSLATRAREGKLKPHEFQGGTFTVSNLGMYGIKNFSAIINPPQACILAVGGSENRLIPADN-EKGFDVASMMSVTLSCDHRVVDGAVGAQWLAEFKKFLEKPTTM 626          

Query:  232 RNYADYPSHKVITLPNLSPTMETGSVLSWGRKEGEAVAEGDLLAEIETDKATMSMDASDNGIMAKILVAAGTKDIPIGTPLCVIVENESDVAAFKDF 522
            R +   P H+ + LP LSPTM+ G++  W +KEG+ + EGDL+AE+ETDKAT+  ++ + G MAKILVA GT+D+PIG+ +C+ V+    + AFK++
Sbjct:   64 RRWYSLPPHQKVPLPALSPTMQMGTIARWEKKEGDKINEGDLIAEVETDKATVGFESLEEGYMAKILVAEGTRDVPIGSVICITVDKPEFIDAFKNY 160          

Query:  247 YPSHKVITLPNLSPTMETGSVLSWGRKEGEAVAEGDLLAEIETDKATMSMDASDNGIMAKILVAAGTKDIPIGTPLCVIVENESDVAAFKDFKXXXXXXXXXXXXXXXXXXXXXXXXXXXMESTKTXXXXXXXXXXXXXXGNRIFVSPYAKTLAAERNIDLATAGIAGSGPDGRIRASDLDQASSPLRTVGQQLSSSTASYTDIELSNMRKVIAQRLCISKQTIPHYYLTMDVRMNRVLEMRSKLNKKHEKSGIKISVNDFVIKASALACMRVLPCNSSWQDTFIRQYNQVDVSVAVATPNGLITPIVFSAHSKGLKEINNDVITLAAKARDNKLQPKEFQGGTFTVSNLGMYGISNFSAIINPPQACILAVGGSQNRLVANDKCDSGFSKATYMSVTLCCDHRVVDGAVGAQWLQEFRDNLEDPENM 1530
            YP+H  I LP LSPTM  G+V  W +K GE ++EGDLLAEIETDKAT+  +  + G +AKIL+  GT+D+P+GTPLC+IVE ESD+ +F+D+K  +  A       A T   A P  P        P  +   +A       R+F+SP A+ LA+E+ ID+    + G   +  I        + P   V    +  +  +TD+ +SN+R+VIAQRL  SKQTIPHYYL++D+ M  ++++R +LN+  +   IK+SVNDF+IKASALAC++V   NSSW DT IRQ++ VDVSVAV+TP GLITPIVF+AH+KGL  I+ DV++LA +AR+ KL+P EFQGGTFTVSNLGMYGI NFSAIINPPQACILAVGGS+NRL+  D  + GF  A+ MSVTL CDHRVVDGAVGAQWL EF+  LE P  M
Sbjct:  144 YPNHMKICLPALSPTMTMGTVQKWEKKVGEKLSEGDLLAEIETDKATIGFEVPEEGYLAKILIEEGTRDVPLGTPLCIIVEKESDIGSFEDYKELTGVADIKPQPAAPTPTAAPPPVPQVAVPPPAPTPSTAPSAPK----GRVFISPLARKLASEKGIDIKQ--VKGEHIEKNISVGKKKSFAVPSPAVA---AVPSGVFTDVPISNIRRVIAQRLMQSKQTIPHYYLSIDINMGEIVQLRKELNEVTKADNIKLSVNDFIIKASALACLKVPEANSSWLDTVIRQHHVVDVSVAVSTPVGLITPIVFNAHTKGLATISKDVLSLATRAREGKLKPHEFQGGTFTVSNLGMYGIKNFSAIINPPQACILAVGGSENRLIPADN-EKGFDVASMMSVTLSCDHRVVDGAVGAQWLAEFKKFLEKPTTM 561          

Query:  244 DYPSHKVITLPNLSPTMETGSVLSWGRKEGEAVAEGDLLAEIETDKATMSMDASDNGIMAKILVAAGTKDIPIGTPLCVIVENESDVAAFKDF 522
            D+ +   + LP LSPTM+ G++  W +KEG+ + EGDL+AE+ETDKAT+  ++ + G MAKILVA GT+D+PIG+ +C+ V+    + AFK++
Sbjct:   20 DFSNVTGVPLPALSPTMQMGTIARWEKKEGDKINEGDLIAEVETDKATVGFESLEEGYMAKILVAEGTRDVPIGSVICITVDKPEFIDAFKNY 112          

Query:  847 YTDIELSNMRKVIAQRLCISKQTIPHYYLTMDVRMNRVLEMRSKLNKKHEKSGIKISVNDFVIKASALACMRVLPCNSSWQDTFIRQYNQVDVSVAVATPNGLITPIVFSAHSKGLKEINNDVITLAAKARDNKLQPKEFQGGTFTVSNLGMYGISNFSAIINPPQACILAVGGSQNR--LVANDKCDSGFSKATYMSVTLCCDHRVVDGAVGAQWLQEFRDNLEDP 1521
            +++I  SN+RKVIA+RL  SK +IPH Y T D  +  V+ +R +L K +    IK+SVNDF+IKA+A A  ++   N +W          +D+S+AVAT  GLITPI+  A SKG++EI      LA KARD KL P+E+QGG+F++SNLGM+GI+ FSA+INPPQ+CILAVG S+    L   ++ +    +   M+VTL  D R+VD  + +++L  FR NLE+P
Sbjct:  231 FSEIPASNIRKVIAKRLMESKSSIPHAYATTDCDLGAVMRLRKELAKDN----IKVSVNDFIIKATAAALKQMPEVNVTWNGEGAAPLETIDISIAVATDRGLITPIIKQAASKGIQEIAATAKVLAQKARDGKLLPEEYQGGSFSISNLGMFGITGFSAVINPPQSCILAVGRSRVELDLAEGEEGNPQLCQKHVMNVTLSSDGRLVDDELASKFLDCFRKNLENP 453          

Query:  265 ITLPNLSPTMETGSVLSWGRKEGEAVAEGDLLAEIETDKATMSMDASDNGIMAKILVAAGTKDIPIGTPLCVIVENESD 501
            + +P LSPTME G+++ W +KEGE V+ GD L EIETDKA ++M+++D+G++AKILV  G++++ +G+ + ++VE   D
Sbjct:   21 VFMPALSPTMEEGNIVKWMKKEGETVSAGDALCEIETDKAVVTMESNDDGVLAKILVEEGSRNVRLGSLIALLVEEGQD 99          

Query:  847 YTDIELSNMRKVIAQRLCISKQTIPHYYLTMDVRMNRVLEMRSKLNKKHEKSGIKISVNDFVIKASALACMRVLPCNSSWQDTFIRQYNQVDVSVAVATPNGLITPIVFSAHSKGLKEINNDVITLAAKARDNKLQPKEFQGGTFTVSNLGMYGISNFSAIINPPQACILAVGGSQNR--LVANDKCDSGFSKATYMSVTLCCDHRVVDGAVGAQWLQEFRDNLEDP 1521
            +++I  SN+RKVIA+RL  SK +IPH Y T D  +  V+ +R +L K +    IK+SVNDF+IKA+A A  ++   N +W          +D+S+AVAT  GLITPI+  A SKG++EI      LA KARD KL P+E+QGG+F++SNLGM+GI+ FSA+INPPQ+CILAVG S+    L   ++ +    +   M+VTL  D R+VD  + +++L  FR NLE+P
Sbjct:  260 FSEIPASNIRKVIAKRLMESKSSIPHAYATTDCDLGAVMRLRKELAKDN----IKVSVNDFIIKATAAALKQMPEVNVTWNGEGAAPLETIDISIAVATDRGLITPIIKQAASKGIQEIAATAKVLAQKARDGKLLPEEYQGGSFSISNLGMFGITGFSAVINPPQSCILAVGRSRVELDLAEGEEGNPQLCQKHVMNVTLSSDGRLVDDELASKFLDCFRKNLENP 482          

Query:  259 KVITLPNLSPTMETGSVLSWGRKEGEAVAEGDLLAEIETDKATMSMDASDNGIMAKILVAAGTKDIPIGTPLCVIVENESD 501
            +++ +P LSPTME G+++ W +KEGE V+ GD L EIETDKA ++M+++D+G++AKILV  G++++ +G+ + ++VE   D
Sbjct:   59 QLVFMPALSPTMEEGNIVKWMKKEGETVSAGDALCEIETDKAVVTMESNDDGVLAKILVEEGSRNVRLGSLIALLVEEGQD 139          

Query:  241 ADYPSHKVITLPNLSPTMETGSVLSWGRKEGEAVAEGDLLAEIETDKATMSMDASDNGIMAKILVAAGTKDIPIGTPLCVIVENESDVAAFKDFKXXXXXXXXXXXXXXXXXXXXXXXXXXXMESTKTXXXXXXXXXXXXXXGNRIFVSPYAKTLAAERNIDLATAGIAGSGPDGRIRASDLDQ----------ASSPLRTVGQQLSSSTASYTDIELSNMRKVIAQRLCISKQTIPHYYLTMDVRMNRVLEMRSKLNKKHEKSGIKISVNDFVIKASALACMRVLPCNSSWQDTFIRQYNQVDVSVAVATPNGLITPIVFSAHSKGLKEINNDVITLAAKARDNKLQPKEFQGGTFTVSNLGMYGISNFSAIINPPQACILAVGGSQNRLVANDKCDSGFSKATYMSVTLCCDHRVVDGAVGAQWLQEFRDNLEDPENM 1530
            + YP+H  I LP LSPTM  G+V  W +K GE ++EGDLLAEIETDKAT+  +  + G +AKILV  GT+D+P+G PLC+IVE + D+AAF D++ +   +     +P    P A                 P  +A+   P  R+FVSP AK LAAE+ IDL    + G+GP+GRI   D+D           A++      +   +    +TDI +SN+R+VIAQRL  SKQTIPHYYL++DV M  VL +R +LNK  E  G KISVNDF+IKASALAC++V   NSSW DT IRQ + VDVSVAV+TP GLITPIVF+AH KGL+ I +DV++LA+KAR+ KLQP EFQGGTFT+SNLGM+GI NFSAIINPPQACILA+G S+++L+  D  + GF  A+ MSVTL CDHRVVDGAVGAQWL EF+  LE P  M
Sbjct:  212 SSYPTHMQIVLPALSPTMTMGTVQRWEKKVGEKLSEGDLLAEIETDKATIGFEVQEEGYLAKILVPEGTRDVPLGAPLCIIVEKQEDIAAFADYRPTEVTSLKPQAAPPAPPPVA-------AVPPTPQPVAPTPSAAPAGPKGRVFVSPLAKKLAAEKGIDLTQ--VKGTGPEGRIIKKDIDSFVPSKAAPAAAAAMAPPGPRVAPAPAGVFTDIPISNIRRVIAQRLMQSKQTIPHYYLSVDVNMGEVLLVRKELNKMLEGKG-KISVNDFIIKASALACLKVPEANSSWMDTVIRQNHVVDVSVAVSTPAGLITPIVFNAHIKGLETIASDVVSLASKAREGKLQPHEFQGGTFTISNLGMFGIKNFSAIINPPQACILAIGASEDKLIPADN-EKGFDVASVMSVTLSCDHRVVDGAVGAQWLAEFKKYLEKPITM 640          

Query:  229 SRNYADYPSHKVITLPNLSPTMETGSVLSWGRKEGEAVAEGDLLAEIETDKATMSMDASDNGIMAKILVAAGTKDIPIGTPLCVIVENESDVAAFKDF 522
            SR     P H+ + LP+LSPTM+ G++  W +KEGE ++EGDL+AE+ETDKAT+  ++ +   MAKILV  GT+D+P+G+ +C+ VE   D+ AFK++
Sbjct:   81 SRRSYSLPPHQKVPLPSLSPTMQAGTIARWEKKEGEKISEGDLIAEVETDKATVGFESLEECYMAKILVPEGTRDVPVGSIICITVEKPQDIEAFKNY 178          

Query:  265 ITLPNLSPTMETGSVLSWGRKEGEAVAEGDLLAEIETDKATMSMDASDNGIMAKILVAAGTKDIPIGTPLCVIV---ENESDVAAFKDFKXXXXXXXXXXXXXXXXXXXXXXXXXXXMESTKTXXXXXXX----------XXXXXXXGNR-IFVSPYAKTLAAERNIDLATAGIAGSGPDGRIRASDLDQASS----------PLRTVGQQLSSSTASYTDIELSNMRKVIAQRLCISKQTIPHYYLTMDVRMNRVLEMRSKLNKKHEKSGIKISVNDFVIKASALACMRVLPCNSSWQDTFIRQYNQVDVSVAVATPNGLITPIVFSAHSKGLKEINNDVITLAAKARDNKLQPKEFQGGTFTVSNLGMYGISNFSAIINPPQACILAVGGSQN--RLVANDKCDSGFSKATYMSVTLCCDHRVVDGAVGAQWLQEFRDNLEDP 1521
            + +P+LSPTME G+++ W RKEGEAV+ GD L EIETDKA +++DA+D+GI+AKI+V  G K+I +G+ + ++V   E+   V   KD       +     +    +P          + T     +P            A+   A G R IF    A  L   + +   T     S P   + AS   QA++          P+   GQ   ++  ++T+I  SN+R+VIA+RL  SK T+PH Y T D  +  VL++R  L K      IK+SVNDF+I+A+A+   ++   N +W     +Q   VD+SVAVAT  GLITPI+  A +KG++EI + V  L+ KARD KL P+E+QGG+F++SNLGM+GI  F+A+INPPQACILAVG  +   +L  +++ +    +   ++VT+  D RVVD  +  ++L+ F+ NLE+P
Sbjct:   59 VLMPSLSPTMEQGNIVKWLRKEGEAVSAGDSLCEIETDKAVVTLDANDDGILAKIVVEEGAKNIQLGSLIALMVEEGEDWKQVEIPKDVSAPPPVSKPPAPTQPSPQPQIPCPARKEHKGTARFRLSPAARNILEKHSLDASQGTATGPRGIFTKEDALKLVELKQMGKITESRPASAPPPSLSASVPPQATAGPSYPRPMTPPVSIPGQ--PNAAGTFTEIPASNIRRVIAKRLTESKSTVPHAYATADCDLGAVLKVRRDLVKDD----IKVSVNDFIIRAAAVTLKQMPGVNVTWDGEGPKQLPSVDISVAVATDKGLITPIIKDAAAKGIQEIADSVKVLSKKARDGKLMPEEYQGGSFSISNLGMFGIDEFAAVINPPQACILAVGRFRPVLKLTEDEEGNPQLQQHQLITVTMSSDSRVVDDELATRFLETFKANLENP 497          

Query:  859 ELSNMRKVIAQRLCISKQTIPHYYLTMDVRMNRVLEMRSKLNKKH-EKSGIKISVNDFVIKASALACMRVLPCNS----SWQDTFIRQYNQVDVSVAVATPNGLITPIVFSAHSKGLKEINNDVITLAAKARDNKLQPKEFQGGTFTVSNLGMYGISNFSAIINPPQACILAVGGSQNRLVANDKCDSGFSKATYMSVTLCCDHRVVDGAVGAQWLQEFRDNLEDP 1521
            +++ MR+ IAQRL  ++ T        +V M+ + EMR++      +K  +K+      +KASA A       N+    + ++   R Y  +D+SVAVATP GL+ P++ +  +    +I   +  L  KAR N+L  ++  GGTFT+SN G++G    + IINPPQ+ IL +    +R VA             M V L  DHR++DG     +L++ +  +EDP
Sbjct:  227 KMNRMRQRIAQRLKEAQNTCAMLTTFNEVDMSNIQEMRARHKDAFLKKHNLKLGFMSAFVKASAFALQEQPVVNAVIDDATKEVVYRDY--IDISVAVATPRGLVVPVIRNVETMNYADIERTINELGEKARKNELAIEDMDGGTFTISNGGVFGSLFGTPIINPPQSAILGMHAIFDRPVA---VGGKVEVRPMMYVALTYDHRLIDGREAVTFLRKIKAAVEDP 447          

Query:  859 ELSNMRKVIAQRLCISKQTIPHYYLTMDVRMNRVLEMRSKLNKKH-EKSGIKISVNDFVIKASALACMRVLPCNS----SWQDTFIRQYNQVDVSVAVATPNGLITPIVFSAHSKGLKEINNDVITLAAKARDNKLQPKEFQGGTFTVSNLGMYGISNFSAIINPPQACILAVGGSQNRLVANDKCDSGFSKATYMSVTLCCDHRVVDGAVGAQWLQEFRDNLEDP 1521
            +++ MR+ IAQRL  ++ T        +V M+ + EMR++      +K  +K+      +KASA A       N+    + ++   R Y  +D+SVAVATP GL+ P++ +  +    +I   +  L  KAR N+L  ++  GGTFT+SN G++G    + IINPPQ+ IL +    +R VA             M V L  DHR++DG     +L++ +  +EDP
Sbjct:  227 KMNRMRQRIAQRLKEAQNTCAMLTTFNEVDMSNIQEMRARHKDAFLKKHNLKLGFMSAFVKASAFALQEQPVVNAVIDDATKEVVYRDY--IDISVAVATPRGLVVPVIRNVETMNYADIERTINELGEKARKNELAIEDMDGGTFTISNGGVFGSLFGTPIINPPQSAILGMHAIFDRPVA---VGGKVEVRPMMYVALTYDHRLIDGREAVTFLRKIKAAVEDP 447          

Query:  316 WGRKEGEAVAEGDLLAEIETDKATMSMDASDNGIMAKILVAAGTKDIP-IGTPLCVIVENESDVAAFKDFKXXXXXXXXXXXXXXXXXXXXXXXXXXXMESTKTXXXXXXXXXXXXXXGNRIFVSPYAKTLAAERNIDLATAGIAGSGPDGRIRASDL-----------------DQASSPL-----RTVGQQLSSS---TASYTDIELSNMRKVIAQRLCISKQTIPHYYLTMDVRMNRVLEMRSKLNKKHEKSGIKISVNDFVIKASALACMRVLPCNSSWQD-----TFIRQYNQVDVSVAVATPNGLITPIVFSAHSKGLKEINNDVITLAAKARDNKLQPKEFQGGTFTVSNLGMYGISNFSAIINPPQACILAVGGSQNRLVANDKCDSGFSKATYMSVTLCCDHRVVDGAVGAQWLQEFRDNLEDPENM 1530
            W  KEG+ V++ D + E+++DKA++++ +  +G++ ++       DI  +G PL + +E E    A KD +                            +  +TP  +          G +   +P  + LA E NI L+   + GSG DGRI   D+                  + + P      RT    ++     T       ++  +K + + +  + + IPH+    ++ + +++++R +L       GIK+S   F +KA++L  ++    N+S  +     T+   +N   + +A+ T  GLI P V +   + + EI  ++  L       +L   +  GGTFT+SN+G  G +    +I PP+  I A+G  +     + K D    KA  M+V+   DHRV+DGA  +++   ++  LE+P  M
Sbjct:   84 WYVKEGDTVSQFDSICEVQSDKASVTITSRYDGVIKRLYY--NLDDIAYVGKPL-IDIETE----ALKDSEE---------------------------DVVETPAVSHDEHTHQEIKGQKTLATPAVRRLAMENNIKLSE--VVGSGKDGRILKEDILSFLEKQTGAILPPSPKSEITPPPPQPKDRTFPTPIAKPPVFTGKDRTEPVTGFQKAMVKTMSAALK-IPHFGYCDEIDLTQLVKLREELKPVALARGIKLSFMPFFLKAASLGLLQFPILNASVDENCQNITYKASHN---IGIAMDTELGLIVPNVKNVQVRSVFEIAMELNRLQKLGSSGQLGTTDLTGGTFTLSNIGSIGGTYAKPVILPPEVAIGALGAIKALPRFDQKGD--VYKAQIMNVSWSADHRVIDGATMSRFSNLWKSYLENPAFM 477          

Query:  241 ADYPSHKVITLPNLSPTMETGSVLSWGRKEGEAVAEGDLLAEIETDKATMSMDASDNGIMAKILVAAGTKDIPIGTPLCVIVENESDVAAFKDFKXXXXX-XXXXXXXXXXXXXXXXXXXXXXMESTKTXXXXXXXXXXXXXXGNRIFVSPYAKTLAAERNIDLATAGIAGSGPDGRIRASDLDQ---------ASSPLRTVGQQLSS-STASYTDIELSNMRKVIAQRLCISKQTIPHYYLTMDVRMNRVLEMRSKLNKKHEKSGIKISVNDFVIKASALACMRVLPCNSSWQDTFIRQYNQVDVSVAVATPNGLITPIVFSAHSKGLKEINNDVITLAAKARDNKLQPKEFQGGTFTVSNLGMYGISNFSAIINPPQACILAVGGSQNRLVANDKCDSGFSKATYMSVTLCCDHRVVDGAVGAQWLQEFRDNLEDPENM 1530
            + YP H  + LP LSPTM  G+V  W +K GE ++EGDLLAEIETDKAT+  +  + G +AKILV  GT+D+P+GTPLC+IVE E+D++AF D++ +        +  P      A P  P P+  T +       A        R+FVSP AK LA E+ IDL    + G+GPDGRI   D+D           ++ +   G  ++   T  +TDI +SN+R+VIAQRL  SKQTIPHYYL++DV M  VL +R +LNK  E    KISVNDF+IKASALAC++V   NSSW DT IRQ + VDVSVAV+TP GLITPIVF+AH KG++ I NDV++LA KAR+ KLQP EFQGGTFT+SNLGM+GI NFSAIINPPQACILA+G S+++LV  D  + GF  A+ MSVTL CDHRVVDGAVGAQWL EFR  LE P  M
Sbjct:  213 SSYPPHMQVLLPALSPTMTMGTVQRWEKKVGEKLSEGDLLAEIETDKATIGFEVQEEGYLAKILVPEGTRDVPLGTPLCIIVEKEADISAFADYRPTEVTDLKPQVPPPTPPPVAAVPPTPQPLAPTPSAPCPATPAGPK----GRVFVSPLAKKLAVEKGIDLTQ--VKGTGPDGRITKKDIDSFVPSKVAPAPAAVVPPTGPGMAPVPTGVFTDIPISNIRRVIAQRLMQSKQTIPHYYLSIDVNMGEVLLVRKELNKILEGRS-KISVNDFIIKASALACLKVPEANSSWMDTVIRQNHVVDVSVAVSTPAGLITPIVFNAHIKGVETIANDVVSLATKAREGKLQPHEFQGGTFTISNLGMFGIKNFSAIINPPQACILAIGASEDKLVPADN-EKGFDVASMMSVTLSCDHRVVDGAVGAQWLAEFRKYLEKPITM 645          

Query:  232 RNYADYPSHKVITLPNLSPTMETGSVLSWGRKEGEAVAEGDLLAEIETDKATMSMDASDNGIMAKILVAAGTKDIPIGTPLCVIVENESDVAAFKDF 522
            R Y   P H+ + LP+LSPTM+ G++  W +KEG+ + EGDL+AE+ETDKAT+  ++ +   MAKILVA GT+D+PIG  +C+ V    D+ AFK++
Sbjct:   83 RRYYSLPPHQKVPLPSLSPTMQAGTIARWEKKEGDKINEGDLIAEVETDKATVGFESLEECYMAKILVAEGTRDVPIGAIICITVGKPEDIEAFKNY 179          

Query:  241 ADYPSHKVITLPNLSPTMETGSVLSWGRKEGEAVAEGDLLAEIETDKATMSMDASDNGIMAKILVAAGTKDIPIGTPLCVIVENESDVAAFKDFKXXXXXXXXXXXXXXXXXXXXXXXXXXXMESTKTXXXXXXXXXXXXXXGNRIFVSPYAKTLAAERNIDLATAGIAGSGPDGRIRASDLDQ---------ASSPLRTVGQQLSSSTASYTDIELSNMRKVIAQRLCISKQTIPHYYLTMDVRMNRVLEMRSKLNKKHEKSGIKISVNDFVIKASALACMRVLPCNSSWQDTFIRQYNQVDVSVAVATPNGLITPIVFSAHSKGLKEINNDVITLAAKARDNKLQPKEFQGGTFTVSNLGMYGISNFSAIINPPQACILAVGGSQNRLVANDKCDSGFSKATYMSVTLCCDHRVVDGAVGAQWLQEFRDNLEDPENM 1530
            + YP H  I LP LSPTM  G+V  W +K GE ++EGDLLAEIETDKAT+  +  + G +AKILV  GT+D+P+GTPLC+IVE + D+AAF D++ +   +      P    P A                 P  +A+   P  R+FVSP AK LAAE+ IDL    + G+GP+GRI   D+D          A++      +   +    + DI +SN+R+VIAQRL  SKQTIPHYYL++DV M  VL +R +LNK  E  G KISVNDF+IKASALAC++V   NSSW DT IRQ + VDVSVAV+TP GLITPIVF+AH KGL+ I +DV++LA+KAR+ KLQP EFQGGTFT+SNLGM+GI NFSAIINPPQACILA+G S+++L+  D  + GF  A+ MSVTL CDHRVVDGAVGAQWL EF+  LE P  M
Sbjct:  203 SSYPVHMQIVLPALSPTMTMGTVQRWEKKVGEKLSEGDLLAEIETDKATIGFEVQEEGYLAKILVPEGTRDVPLGTPLCIIVEKQEDIAAFADYRPTEVTSLKPQAPPPVPPPVA-------AVPPIPQPLAPTPSAAPAGPKGRVFVSPLAKKLAAEKGIDLTQ--VKGTGPEGRIIKKDIDSFVPTKAAPAAAAAAPPGPRVAPTPAGVFIDIPISNIRRVIAQRLMQSKQTIPHYYLSVDVNMGEVLLVRKELNKMLEGKG-KISVNDFIIKASALACLKVPEANSSWMDTVIRQNHVVDVSVAVSTPAGLITPIVFNAHIKGLETIASDVVSLASKAREGKLQPHEFQGGTFTISNLGMFGIKNFSAIINPPQACILAIGASEDKLIPADN-EKGFDVASVMSVTLSCDHRVVDGAVGAQWLAEFKKYLEKPVTM 630          

Query:  184 YSRKFLVDNRISQLI----SRNYADYPSHKVITLPNLSPTMETGSVLSWGRKEGEAVAEGDLLAEIETDKATMSMDASDNGIMAKILVAAGTKDIPIGTPLCVIVENESDVAAFKDF 522
            Y    +  NRI Q +    SR     P H+ + LP+LSPTM+ G++  W +KEGE ++EGDL+AE+ETDKAT+  ++ +   MAKILV  GT+D+P+G+ +C+ VE   D+ AFK++
Sbjct:   54 YGSATVPRNRILQQLLGSPSRRSYSLPPHQKVPLPSLSPTMQAGTIARWEKKEGEKISEGDLIAEVETDKATVGFESLEECYMAKILVPEGTRDVPVGSIICITVEKPQDIEAFKNY 170          

Query:  241 ADYPSHKVITLPNLSPTMETGSVLSWGRKEGEAVAEGDLLAEIETDKATMSMDASDNGIMAKILVAAGTKDIPIGTPLCVIVENESDVAAFKDFKXXXXXXXXXXXXXXXXXXXXXXXXXXXMESTKTXXXXXXXXXXXXXXGNRIFVSPYAKTLAAERNIDLATAGIAGSGPDGRIRASDLDQ----------ASSPLRTVGQQLSSSTASYTDIELSNMRKVIAQRLCISKQTIPHYYLTMDVRMNRVLEMRSKLNKKHEKSGIKISVNDFVIKASALACMRVLPCNSSWQDTFIRQYNQVDVSVAVATPNGLITPIVFSAHSKGLKEINNDVITLAAKARDNKLQPKEFQGGTFTVSNLGMYGISNFSAIINPPQACILAVGGSQNRLVANDKCDSGFSKATYMSVTLCCDHRVVDGAVGAQWLQEFRDNLEDPENM 1530
            + YP+H  I LP LSPTM  G+V  W +K GE ++EGDLLAEIETDKAT+  +  + G +AKILV  GT+D+P+G PLC+IVE + D+AAF D++ +   +     +P    P A                 P  +A+   P  R+FVSP AK LAAE+ IDL    + G+GP+GRI   D+D           A++      +   +    +TDI +SN+R+VIAQRL  SKQTIPHYYL++DV M  VL +R +LNK  E  G KISVNDF+IKASALAC++V   NSSW DT IRQ + VDVSVAV+TP GLITPIVF+AH KGL+ I +DV++LA+KAR+ KLQP EFQGGTFT+SNLGM+GI NFSAIINPPQACILA+G S+++L+  D  + GF  A+ MSVTL CDHRVVDGAVGAQWL EF+  LE P  M
Sbjct:  212 SSYPTHMQIVLPALSPTMTMGTVQRWEKKVGEKLSEGDLLAEIETDKATIGFEVQEEGYLAKILVPEGTRDVPLGAPLCIIVEKQEDIAAFADYRPTEVTSLKPQAAPPAPPPVA-------AVPPTPQPVAPTPSAAPAGPKGRVFVSPLAKKLAAEKGIDLTQ--VKGTGPEGRIIKKDIDSFVPSKAAPAAAAAMAPPGPRVAPAPAGVFTDIPISNIRRVIAQRLMQSKQTIPHYYLSVDVNMGEVLLVRKELNKMLEGKG-KISVNDFIIKASALACLKVPEANSSWMDTVIRQNHVVDVSVAVSTPAGLITPIVFNAHIKGLETIASDVVSLASKAREGKLQPHEFQGGTFTISNLGMFGIKNFSAIINPPQACILAIGASEDKLIPADN-EKGFDVASVMSVTLSCDHRVVDGAVGAQWLAEFKKYLEKPITM 640          

Query:  229 SRNYADYPSHKVITLPNLSPTMETGSVLSWGRKEGEAVAEGDLLAEIETDKATMSMDASDNGIMAKILVAAGTKDIPIGTPLCVIVENESDVAAFKDF 522
            SR     P H+ + LP+LSPTM+ G++  W +KEGE ++EGDL+AE+ETDKAT+  ++ +   MAKILV  GT+D+P+G+ +C+ VE   D+ AFK++
Sbjct:   81 SRRSYSLPPHQKVPLPSLSPTMQAGTIARWEKKEGEKISEGDLIAEVETDKATVGFESLEECYMAKILVPEGTRDVPVGSIICITVEKPQDIEAFKNY 178          

Query:  214 ISQLISRNYADYPSHKVITLPNLSPTMETGSVLSWGRKEGEAVAEGDLLAEIETDKATMSMDASDNGIMAKILVAAGTKDIPIGTPLCVIVENESDVAAFKDFKXXXXXXXXXXXXXXXXXXXXXXXXXXXMESTKTXXXXXXXXXXXX---XXGNRIFVSPYAKTLAAERNIDLATAGIAGSGPDGRIRASDLDQASSPLRTVGQQLSSSTASYTDIELSNMRKVIAQRLCISKQTIPHYYLTMDVRMNRVLEMRSKLN----KKHEKSGIKISVNDFVIKASALACMRVLPCNSSWQDTFIRQYNQVDVSVAVATPNGLITPIVFSAHSKGLKEINNDVITLAAKARDNKLQPKEFQGGTFTVSNLGMYG-ISNFSAIINPPQACILAVGGSQNRLVANDKCDSGFSKATYMSVTLCCDHRVVDGAVGAQWLQEFRDNLEDPENM 1530
            I Q+   +  + P H  + LP LSPTME G+V+SW +KEG+ ++EGDLL EIETDKATM  +  + G +AKIL+  G+KD+PIG  LC+IV+NE+DVAAFKDFK   + +     +  K    A P               P V  S P   +   R+  SP+AK LAAE  +DL+    +G    GRI ASDL QA +   T     + S   YTDI LSNMRK IA+RL  SK TIPHYYLT +++++ +L++R KLN    K       KIS+NDF+IKASALAC RV   NS W D+FIR+ + VDVSVAV+TP GLITPI+F+AH+KGL  I ++++ LA +AR+ KLQP EFQGGTFTVSNLGM+G +S+F+AIINPPQ+CILA+GG+ ++LV ++    G+ K   M VTL CDHR VDGAVGA WL+ F++ LE P  M
Sbjct:   63 IKQVRLYSSGNLPKHNRVALPALSPTMELGTVVSWQKKEGDQLSEGDLLCEIETDKATMGFETPEEGYLAKILIQEGSKDVPIGKLLCIIVDNEADVAAFKDFKDDGASSGGSAPAAEKAPEPAKPAASSQPSPPAQMYQAPSVPKSAPIPHSSSGRVSASPFAKKLAAENGLDLSGVSGSGP--GGRILASDLSQAPAKGATSTTTQAVSGQDYTDIPLSNMRKTIAKRLTESKSTIPHYYLTSEIQLDTLLQVREKLNGLLAKGTSGQATKISINDFIIKASALACQRVPEANSYWMDSFIRENHHVDVSVAVSTPAGLITPIIFNAHAKGLATIASEIVELAQRAREGKLQPHEFQGGTFTVSNLGMFGSVSDFTAIINPPQSCILAIGGASDKLVPDEA--EGYKKIKTMKVTLSCDHRTVDGAVGAVWLRHFKEFLEKPHTM 505          

Query:  241 ADYPSHKVITLPNLSPTMETGSVLSWGRKEGEAVAEGDLLAEIETDKATMSMDASDNGIMAKILVAAGTKDIPIGTPLCVIVENESDVAAFKDFKXXXXXXXXXXXXXXXXXXXXXXXXXXXMESTKTXXXXXXXXXXXXXXGNRIFVSPYAKTLAAERNIDLATAGIAGSGPDGRIRASDLDQ-ASSPLRTVGQQLSSSTAS------YTDIELSNMRKVIAQRLCISKQTIPHYYLTMDVRMNRVLEMRSKLNKKHEKSGIK-ISVNDFVIKASALACMRVLPCNSSWQDTFIRQYNQVDVSVAVATPNGLITPIVFSAHSKGLKEINNDVITLAAKARDNKLQPKEFQGGTFTVSNL-GMYGISNFSAIINPPQACILAVGGSQNRLVANDKCDSGFSKATYMSVTLCCDHRVVDGAVGAQWLQEFRDNLEDPENM 1530
            +D P H+ I +P+LSPTM  G++  W +KEG+ VA G++L E+ETDKAT+ M+  + G +AKI+ A G+K+I +G  + + VE+E D+  FKD+    +P+S+   +P K EPT AP     ++   +P        S P  G+R+F SP A+ LA + N+ L+   I G+GP+GRI  +D+D+  +S  +    + S ST S      Y DI  S +RKV A RL  SKQTIPHYYLT+D  +++++ +RS+LN   E SG K ISVND V+KA+ALA  +V  CNSSW D +IRQ+  V+++VAV T NGL  P+V  A  KGL  I  +V  LA KA++N L+P++++GGTFTVSNL G +GI  F A++NPPQA ILAVG ++ R+V  +  D  F+ A+YM VTL CDHRVVDGA+GA+WL+ F+  +E+P++M
Sbjct:  106 SDLPPHQEIGMPSLSPTMTEGNIARWLKKEGDKVAPGEVLCEVETDKATVEMECMEEGYLAKIVKAEGSKEIQVGEVIAITVEDEEDIGKFKDY----TPSSTADAAPTKAEPTPAPPKEEKVKQPSSPPEPKASKPSTPPTGDRVFASPLARKLAEDNNVPLSD--IEGTGPEGRIVKADIDEYLASSGKGATAKPSKSTDSKAPALDYVDIPHSQIRKVTASRLAFSKQTIPHYYLTVDTCVDKLMALRSQLNSFKEASGGKRISVNDLVVKAAALALRKVPQCNSSWTDDYIRQFKNVNINVAVQTENGLYVPVVKDADRKGLSTIGEEVRLLAQKAKENSLKPEDYEGGTFTVSNLGGPFGIKQFCAVVNPPQAAILAVGSAEKRVVPGNGPDQ-FNFASYMPVTLSCDHRVVDGAIGAEWLKAFKGYIENPKSM 537          

Query:  241 ADYPSHKVITLPNLSPTMETGSVLSWGRKEGEAVAEGDLLAEIETDKATMSMDASDNGIMAKILVAAGTKDIPIGTPLCVIVENESDVAAFKDF-----KXXXXXXXXXXXXXXXXXXXXXXXXXXXMESTKTXXXXXXXXXXXXXXGNRIFVSPYAKTLAAERNIDLATAGIAGSGPDGRIRASDLDQASSPLRTVGQQLSSSTAS--YTDIELSNMRKVIAQRLCISKQTIPHYYLTMDVRMNRVLEMRSKLNKKHEKSGIKISVNDFVIKASALACMRVLPCNSSWQDTFIRQYNQVDVSVAVATPNGLITPIVFSAHSKGLKEINNDVITLAAKARDNKLQPKEFQGGTFTVSNLGMYGISNFSAIINPPQACILAVGGSQNRLVANDKCDSGFSKATYMSVTLCCDHRVVDGAVGAQWLQEFRDNLEDPENM 1530
            AD PSH  +TLP LSPTMETG++ SW +KEG+ V+EGDLLAEIETDKAT+  ++S+ G +AKI V  GTK++P+G  +C+IV N+ DVAAFKD+            S    +  + EP A   P P   +  +P +  P  A   A G R+F +P+AKTLA+E+ IDL    + GSGP+G+IRA+DL   S                  + DI L+N+R+VIA+RL +SKQTIPHYYLT+DV+++ +L +R  LN+   KSG+K+SVNDF+IKASALAC +V   NSSWQDTFIRQYN VDV+VAVAT NGLITPIVF A +KGL +I  DV +LAAKAR+ KL+P+EFQGGTFT+SNLGM+GI  F+A+INPPQ+CILAVGG+  RLV ++  DSGF  AT M+VTL CDHRVVDGAVGAQWL EFR  LE PE M
Sbjct:   39 ADLPSHSKVTLPALSPTMETGTISSWQKKEGDKVSEGDLLAEIETDKATVGFESSEEGYLAKICVPEGTKEVPLGKVVCIIVNNKEDVAAFKDYVPSPEDDVKIGGSGAPAAVKQPEPAAPAPPAPLPPTAVSPPTAAPTVAPPAASGVRVFATPFAKTLASEKGIDLKQ--VRGSGPEGQIRAADLAGISPGAPAATVAAPVGLPGQLFIDIPLNNIRQVIAKRLTLSKQTIPHYYLTVDVKVDNILRVRKDLNEILSKSGVKLSVNDFIIKASALACKKVPQANSSWQDTFIRQYNSVDVNVAVATDNGLITPIVFGADAKGLADIATDVASLAAKAREGKLKPQEFQGGTFTISNLGMFGIKQFAAVINPPQSCILAVGGADKRLVVSEDSDSGFRTATVMTVTLSCDHRVVDGAVGAQWLAEFRKLLEQPETM 473          

Query:  241 ADYPSHKVITLPNLSPTMETGSVLSWGRKEGEAVAEGDLLAEIETDKATMSMDASDNGIMAKILVAAGTKDIPIGTPLCVIVENESDVAAFKDFKXXXXXXXXXXXXXXXXXXXXXXXXXXXMESTKTXXXXXXXXXXXXXXGNRIFVSPYAKTLAAERNIDLATAGIAGSGPDGRIRASDLD----QASSPLRTVGQQL----SSST-------ASYTDIELSNMRKVIAQRLCISKQTIPHYYLTMDVRMNRVLEMRSKLNKKHEKSGIKISVNDFVIKASALACMRVLPCNSSWQDTFIRQYNQVDVSVAVATPNGLITPIVFSAHSKGLKEINNDVITLAAKARDNKLQPKEFQGGTFTVSNLGMYGISNFSAIINPPQACILAVGGSQNRLVANDKCDSGFSKATYMSVTLCCDHRVVDGAVGAQWLQEFRDNLEDPENM 1530
            + YPSH  ITLP LSPTM  G+V  W +K GE + EGDLLAEIETDKAT+  +  + G +AKI+V  GT+D+P+GTPLC+IVE ESD+AAFKD+          + +      T AP P P   +     +    AA       R+F+SP AK LAAE+ IDLA   ++GSGPDGRI   D+D      ++P+ + G  L     SST        ++TD+ +SN+RKVIAQRL  SKQTIPHYYL++DV M++VLE+R +LN + +   IK+SVNDF+IKASALAC++V  CNSSW DT IRQ + VDVSVAV+T NGLITPIVF+AH+KGL  I++DV  LAAKAR+ KLQP EFQGGTFT+SNLGM+G+ NFSAIINPPQ+CILAVGGS+ RL+  D  + GF  A+ MSVTL CDHRVVDGAVGAQWL EFR  LE P  M
Sbjct:  203 SSYPSHMKITLPALSPTMTMGTVQRWEKKVGEKLGEGDLLAEIETDKATIGFEVQEEGYLAKIMVPEGTRDVPLGTPLCIIVEKESDIAAFKDY----------VETGVADVSTPAPAPAPAPATPTPGPAAAAAAAPSGPRKGRVFISPLAKKLAAEKGIDLAQ--VSGSGPDGRITKKDIDGFVPPKAAPVSSSGTSLLLKPVSSTVYNIAPAGTFTDVPISNIRKVIAQRLMQSKQTIPHYYLSVDVNMDQVLELRKELNDEVKAQNIKLSVNDFIIKASALACLKVPECNSSWMDTLIRQNHVVDVSVAVSTANGLITPIVFNAHTKGLSAISSDVSALAAKAREGKLQPHEFQGGTFTISNLGMFGVKNFSAIINPPQSCILAVGGSEKRLLPADN-EKGFDVASMMSVTLSCDHRVVDGAVGAQWLAEFRRFLEKPVTM 634          

Query:  211 RISQLISR-NYADYPSHKVITLPNLSPTMETGSVLSWGRKEGEAVAEGDLLAEIETDKATMSMDASDNGIMAKILVAAGTKDIPIGTPLCVIVENESDVAAFKD 519
            R  QL +   +   P H+ + LP LSPTM+TG++  W +KEG+ + EGDL+AE+ETDKAT+  +  +   +AKILV  GT+D+ IG  +C+ V++   + AFKD
Sbjct:   64 RCPQLAATCRFYSLPPHQKVELPALSPTMQTGTIARWEKKEGDKINEGDLIAEVETDKATVGFEMLEECYLAKILVPEGTRDVNIGAIICITVDSPELIPAFKD 167          

Query:  241 ADYPSHKVITLPNLSPTMETGSVLSWGRKEGEAVAEGDLLAEIETDKATMSMDASDNGIMAKILVAAGTKDIPIGTPLCVIVENESDVAAFKDFKXXXXXXXXXXXXXXXXXXXXXXXXXXXMESTKTXXXXXXXXXXXXXXGNRIFVSPYAKTLAAERNIDLATAGIAGSGPDGRIRASDLDQ---------ASSPLRTVGQQLSSSTASYTDIELSNMRKVIAQRLCISKQTIPHYYLTMDVRMNRVLEMRSKLNKKHEKSGIKISVNDFVIKASALACMRVLPCNSSWQDTFIRQYNQVDVSVAVATPNGLITPIVFSAHSKGLKEINNDVITLAAKARDNKLQPKEFQGGTFTVSNLGMYGISNFSAIINPPQACILAVGGSQNRLVANDKCDSGFSKATYMSVTLCCDHRVVDGAVGAQWLQEFRDNLEDPENM 1530
            + YPSH  ITLP LSPTM  G+V  W +K GE ++EGDLLAEIETDKAT+  +  + G +AKI+V  GT+D+P+GTPLC+IVE ESD+AAFKD+  +                           ST  P   P           R+FVSP AK +AAE+ IDLA   ++GSGPDGRI   D++          A+             T ++TDI +SN+RKVIAQRL  SKQTIPHYYL++DV M++VLE+R +LN+   ++ IK+SVNDF+IKASALAC++V  CNSSW +T IRQ + VDVSVAV+TPNGLITPIVF++H KGL  I++DV  LAAKAR+ KLQP EFQGGTFT+SNLGM+GI NFSAIINPPQACILAVGGS+ RL+  D  + GF  A+ MSVTL CDHRVVDGAVGAQWL EFR  LE P  M
Sbjct:  202 SSYPSHMKITLPALSPTMTMGTVQRWEKKVGEKLSEGDLLAEIETDKATIGFEVQEEGYLAKIMVQEGTRDVPLGTPLCIIVEKESDIAAFKDYVETGVAEV----------------------STPPPAPAPAPVTPAAPRKGRVFVSPLAKKMAAEKGIDLAQ--VSGSGPDGRITRKDIESFVPPKAAVAAAPAPAPAAPAAVPPTGTFTDIPISNIRKVIAQRLMQSKQTIPHYYLSVDVNMDQVLELRKELNEVKAQN-IKLSVNDFIIKASALACLKVPECNSSWMETVIRQNHVVDVSVAVSTPNGLITPIVFNSHVKGLAAISSDVAALAAKAREGKLQPHEFQGGTFTISNLGMFGIKNFSAIINPPQACILAVGGSEKRLLPADN-EKGFDVASMMSVTLSCDHRVVDGAVGAQWLAEFRKFLEKPVTM 614          

Query:  229 SRNYADYPSHKVITLPNLSPTMETGSVLSWGRKEGEAVAEGDLLAEIETDKATMSMDASDNGIMAKILVAAGTKDIPIGTPLCVIVENESDVAAFKD 519
            SR Y+  P H+ + LP LSPTM+TG++  W +KEG+ ++EGDL+AE+ETDKAT+  +  +   +AKIL+  GT+D+ +G  +C+ V+    V AFKD
Sbjct:   73 SRFYS-LPPHQKVELPALSPTMQTGTIARWEKKEGDKISEGDLIAEVETDKATVGFEMLEECYLAKILIPEGTRDVTVGAVICITVDKPELVEAFKD 168          

Query:  124 SKIESFQHNTPLNRKIHFIH---YSRKFLVDNRI-------SQLISRNYADYPSHKVITLPNLSPTMETGSVLSWGRKEGEAVAEGDLLAEIETDKATMSMDASDNGIMAKILVAAGTKDIPIGTPLCVIVENESDVAAFKDFKXXXXXXXXXXXXXXXXXXXXXXXXXXXMESTKTXXXXXXXXXXXXXXGNRIFVSPYAKTLAAERNIDLATAGIAGSGPDGRIRASDLDQASSPLRTVGQQLSSSTASYTDIELSNMRKVIAQRLCISKQTIPHYYLTMDVRMNRVLEMRSKLNKKHEKSGIKISVNDFVIKASALACMRVLPCNSSWQDTFIRQYNQVDVSVAVATPNGLITPIVFSAHSKGLKEINNDVITLAAKARDNKLQPKEFQGGTFTVSNLGMYGISNFSAIINPPQACILAVGGSQNRLVANDKCDSGFSKATYMSVTLCCDHRVVDGAVGAQWLQEFRDNLEDPENM 1530
            SK+ S   +  L   +H I    YS   L  N++       S L   +    P H  + LP LSPTME G+++SW +KEG+ + EGDLLAEIETDKATM  +  + G +AKILV AG+KD+P+G  LC+IV NE+D+AAFKDF  S          P+   P ++   P      +   S    +       +RIF SP A++LA ++ IDL+  G+ GSGP GRIRA DL+ A  P    G   ++ ++ + DI ++NMR+VIA+RL  SKQTIPHYYL++DV+M+R+L +R++LN   +K G+K+SVNDF++KA+ALAC +V   NSSW DTFIRQ+N VDVSVAV+T  GLITPIVF A +KGL  I++D  TLA+KAR+ KL+P+EFQGGTFT+SNLGM+GI NFSA+INPPQ+CILAVG +++ L+ ++  + GF  A  MSVTL CDHRVVDGAVGAQWL  F+  LE PE M
Sbjct:   21 SKLHSLTRHQRLALSVHRIACSCYSTNALFHNQLKRSPYVLSPLRQFSSDGLPPHHRVPLPALSPTMEMGTIVSWEKKEGDKLNEGDLLAEIETDKATMGFETPEEGYLAKILVPAGSKDVPLGKLLCIIVSNEADIAAFKDFVDSGEAVKPAAAKPSAPPPPSSAPLPSAPPVPQPIPSVSAPSPGSG--ASRIFASPLARSLARDKGIDLS--GVHGSGPGGRIRAQDLEGAV-PSTPAGMPAAAPSSQFIDIPMTNMRQVIARRLLQSKQTIPHYYLSIDVQMDRILRLRAQLNDMLQKDGVKLSVNDFIVKAAALACKKVPEVNSSWMDTFIRQFNSVDVSVAVSTDAGLITPIVFRADAKGLSTISSDTKTLASKAREGKLRPEEFQGGTFTISNLGMFGIKNFSAVINPPQSCILAVGNTESTLIPDETSEKGFRAAKMMSVTLSCDHRVVDGAVGAQWLVHFKKLLEQPELM 494          

Query:  214 ISQLISRNYA--DYPSHKVITLPNLSPTMETGSVLSWGRKEGEAVAEGDLLAEIETDKATMSMDASDNGIMAKILVAAGTKDIPIGTPLCVIVENESDVAAFKDF--KXXXXXXXXXXXXXXXXXXXXXXXXXXXMESTKTXXXXXXXXXXXXXXGNRIFVSPYAKTLAAERNIDLATAGIAGSGPDGRIRASDLDQASSPLRTVGQQLSSS-----TASYTDIELSNMRKVIAQRLCISKQTIPHYYLTMDVRMNRVLEMRSKLNKKHEKSGIK-ISVNDFVIKASALACMRVLPCNSSWQDTFIRQYNQVDVSVAVATPNGLITPIVFSAHSKGLKEINNDVITLAAKARDNKLQPKEFQGGTFTVSNLGMYGISNFSAIINPPQACILAVGGSQNRLVANDKCDSGFSKATYMSVTLCCDHRVVDGAVGAQWLQEFRDNLEDPENM 1530
            I+ L  R Y+  + PSH  I LP LSPTME+G+++SW +KEG+ V+EGDLLAEIETDKA+M  ++SD G +AKI +  GTKD+P+G  +C+IV +E+DVAAFKD+  K      +    SP      A+  PP P +S      +        A G+R+F +P+AKTLA+E+ IDL +  + GSGPDG++RA+D+ QA+      G   SSS     + S+ D+ LSNMR+VIA+RL +SKQTIPHYYL  ++ + R+L +R  LN   EK G+K +SVNDF+IKASALA  +V   NS+W   FIRQYN +D+ +AVAT NGLITPIVFSA +KGL +I  DV +LAAKAR  KLQP+E+QGGTFT+SNLGM+G+ +FSA+INPPQACILAVGG++ ++V +    SGFS +  M+VTL CDHRVVDGAVGA+WL EF+  +E PE+M
Sbjct:   55 ITSLPQRYYSSGNLPSHVKIVLPALSPTMESGTIISWQKKEGDKVSEGDLLAEIETDKASMGFESSDEGYLAKIFIPEGTKDVPLGKLMCIIVSSEADVAAFKDYVPKPGDDQPTGQAASPPAPAAPASQPPPSPEKSAPPSPPSQATRGPPAAAGDRLFATPFAKTLASEKGIDLRS--VKGSGPDGQVRAADVLQATPGGSAPGAGASSSIVTPSSQSFLDLPLSNMRQVIAKRLTLSKQTIPHYYLNTEINVERILSIRKDLNVSLEKQGLKKLSVNDFIIKASALASKKVPEANSAWMGDFIRQYNTMDICIAVATDNGLITPIVFSAETKGLSQIAQDVASLAAKARAGKLQPQEYQGGTFTISNLGMFGVKSFSAVINPPQACILAVGGAEQKVVVDQASQSGFSTSHVMTVTLSCDHRVVDGAVGARWLTEFKALMEKPESM 501          

Query:  241 ADYPSHKVITLPNLSPTMETGSVLSWGRKEGEAVAEGDLLAEIETDKATMSMDASDNGIMAKILVAAGTKDIPIGTPLCVIVENESDVAAFKDFKXXXXXXXXXXXXXXXXXXXXXXXXXXXMESTKTXXXXXXXXXXXXXXGNRIFVSPYAKTLAAERNIDLATAGIAGSGPDGRIRASDLDQ---------------ASSPLRTVGQQLSSSTASYTDIELSNMRKVIAQRLCISKQTIPHYYLTMDVRMNRVLEMRSKLNKKHEKSGIKISVNDFVIKASALACMRVLPCNSSWQDTFIRQYNQVDVSVAVATPNGLITPIVFSAHSKGLKEINNDVITLAAKARDNKLQPKEFQGGTFTVSNLGMYGISNFSAIINPPQACILAVGGSQNRLVANDKCDSGFSKATYMSVTLCCDHRVVDGAVGAQWLQEFRDNLEDPENM 1530
            + YPSH  I LP LSPTM  G+V  W +K GE + EGDLLAEIETDKAT+  +  + G +AKI+++ GT+D+P+GTPLC++VE ESD+ AF D+              A   P   P+  PP  +     +    A +  A   R+F SP AK LA+E+ IDLA   +AG+GPDGRI   D++                A +P        +  T ++TDI +SN+R+VIAQRL  SKQTIPHYYL++D+ M++VL++R +LN++ +   IK+SVNDF++KASALAC++V   NSSW DT IRQ + VDVS+AV+TPNGLITPIVF+AH KGL  I+ D   LAAKAR+ KLQP EFQGGTFTVSNLGMYGI NFSAIINPPQACILAVGGS+ RL+  D  + GF  ++ MSVTL CDHRVVDGAVGAQWL EFR  LE P NM
Sbjct:  203 SSYPSHMKILLPALSPTMTMGTVQRWEKKVGEKLNEGDLLAEIETDKATIGFEVQEEGYLAKIMISEGTRDVPLGTPLCIMVEKESDIQAFADY--------VETGVAAAPPPAPTPVAAPPPAAAPVAPAAAAAAPAAAARKGRVFASPLAKKLASEKGIDLAQ--VAGTGPDGRITKKDIENFVPAKAAPPLAAAPAAPTPRAAAPAAAAVPTGTFTDIPISNIRRVIAQRLMQSKQTIPHYYLSVDINMDQVLDLRKELNEEVKADNIKLSVNDFIVKASALACLKVPEANSSWMDTVIRQNHVVDVSIAVSTPNGLITPIVFNAHIKGLAAISKDTAMLAAKAREGKLQPHEFQGGTFTVSNLGMYGIKNFSAIINPPQACILAVGGSEKRLLPADN-ERGFDVSSVMSVTLSCDHRVVDGAVGAQWLAEFRKFLEKPMNM 636          

Query:  226 ISRNYADY--PSHKVITLPNLSPTMETGSVLSWGRKEGEAVAEGDLLAEIETDKATMSMDASDNGIMAKILVAAGTKDIPIGTPLCVIVENESDVAAFKDF 522
            +SR+ A Y  P H+ + LP LSPTM+ G++  W +KEG+ + EGDL+AE+ETDKAT+  +  +   +AKILV  GT+D+PIG  +C+ V+    ++AFKDF
Sbjct:   67 LSRSSALYSLPPHQKVELPALSPTMQLGTIARWEKKEGDKINEGDLIAEVETDKATVGFEILEECYLAKILVPEGTRDVPIGAVICITVDKPELISAFKDF 167          

Query:  835 STASYTDIELSNMRKVIAQRLCISKQTIPHYYLTMDVRMNRVLEMRSKLNKKHEKSGIKISVNDFVIKASALACMRVLPCNSSWQDTFIRQYNQVDVSVAVATPNGLITPIVFSAHSKGLKEINNDVITLAAKARDNKLQPKEFQGGTFTVSNLGMYGISNFSAIINPPQACILAVGGSQNRLVANDKC--DSG--FSKATYMSVTLCCDHRVVDGAVGAQWLQEFRDNLEDPENM 1530
            +  ++T++  SN+R+VIAQRL  SK TIPH Y T+D  +  V+++R +L K+     IK+SVNDF++KA+A+    +   N +W     +  + + +S+AVAT  GLITPI+  A  KG++EI  +   LA KAR  KL P+E+QGG+F++SNLGM+GIS FSA+INPPQACILAVG S++ L    +   DSG        M+VTL  D R+VD  + +++L +FR NLE P+ M
Sbjct:  270 APGTFTEVPASNVRRVIAQRLTQSKTTIPHAYATVDCDLGAVMKLRKQLAKEE----IKVSVNDFIVKAAAVTLKEMPEVNVTWSGEGPQALDSIHISIAVATDRGLITPIIKDAADKGVQEIAANAKALAQKARAGKLLPEEYQGGSFSISNLGMFGISGFSAVINPPQACILAVGRSRDELTLAPEGPDDSGPVLRTRQLMTVTLSSDGRLVDDELASRFLDKFRVNLEKPQRM 501          

Query:  265 ITLPNLSPTMETGSVLSWGRKEGEAVAEGDLLAEIETDKATMSMDASDNGIMAKILVAAGTKDIPIGTPLCVIVENESD 501
            + +P LSPTME G+++ W +KEGEAVA GD L EIETDKA ++M+++D+G++AKIL+  G+K + +GT + V+VE   D
Sbjct:   52 VQMPALSPTMEEGNIVKWLKKEGEAVAAGDALCEIETDKAVVTMESNDDGVLAKILMEEGSKSVRLGTLIAVMVEEGED 130          

Query:  856 IELSNMRKVIAQRLCISKQTIPHYYLTMDVRMNRVLEMRSKLNKKH-EKSGIKISVNDFVIKASALACMRVLPCNSSWQDTF--IRQYNQVDVSVAVATPNGLITPIVFSAHSKGLKEINNDVITLAAKARDNKLQPKEFQGGTFTVSNLGMYGISNFSAIINPPQACILAVGGSQNRLVANDKCDSGFSKATYMSVTLCCDHRVVDGAVGAQWLQEFRDNLEDP 1521
            ++++ MR  IAQRL  ++ T        +V M+ + EMR        +K  IK+      +KA+A A M     N+   DT   I   + VD+SVAVATP GL+ P+V         +I   +  L  KAR N+L  ++  GGTFT+SN G++G    + IINPPQ+ IL + G  +R VA             M V L  DHR++DG     +L++ +  +EDP
Sbjct:  226 VKMNRMRLRIAQRLKEAQNTCAMLTTFNEVDMSNITEMRKVYKDAFLKKHNIKLGFMSAFVKAAAYALMDQPAVNAVIDDTTKEIVYRDYVDISVAVATPKGLVVPVVRGVEGMNFTDIEKAINELGEKARKNELAVEDMDGGTFTISNGGVFGSMFGTPIINPPQSAILGMHGIFDRPVA---VGGKVEIRPMMYVALTYDHRLIDGREAVTFLRKIKSVVEDP 447          

Query:  316 WGRKEGEAVAEGDLLAEIETDKATMSMDASDNGIMAKILVAAGTKDIPIGTPLCVI-VENESDVAAFKDFKXXXXXXXXXXXXXXXXXXXXXXXXXXXMESTKTXXXXXXXXXXXXXXGNRIFVSPYAKTLAAERNIDLATAGIAGSGPDGRIRASDL--------------DQASSPLRTVGQQ------LSSSTASYTDI--------ELSNMRKVIAQRLCISKQTIPHYYLTMDVRMNRVLEMRSKLNKKHEKSGIKISVNDFVIKASALACMRVLPCNSSWQD-----TFIRQYNQVDVSVAVATPNGLITPIVFSAHSKGLKEINNDVITLAAKARDNKLQPKEFQGGTFTVSNLGMYGISNFSAIINPPQACILAVGGSQNRLVANDKCDSGFSKATYMSVTLCCDHRVVDGAVGAQWLQEFRDNLEDPENM 1530
            W  K G+ V++ D + E+++DKA++++ +  +G++ K+        + +G+PL  I  + E D A  +D                         P    E T                G++   +P  + LA E NI L+   + G+G DGRI   D+              D+   P+  V         LS   A    +         L+  +K + + +  + + IPH  L  +V + +++ +RS+L    E  G+K+S   F IKA++L  ++    N+S  +     T+   +N   + +A+ TP GL+ P V       + ++  ++  L A     +L   +  GGTFT+SN+G  G +    +I PP+  I A+G  Q     N + D    KA  MS++   DHRV+DGA   ++    R  LE+P +M
Sbjct:   81 WYVKVGDKVSQFDSICEVQSDKASVTITSRYDGVIRKLHHDVDAIAL-VGSPLVDIETDREQDGAPEEDV---------------------VETPAVSHEHTH-----------QEIKGHKTQATPAVRRLAMENNIKLSE--VVGTGKDGRILKEDILNFLAKQTGAILPYDEVKQPVPAVTPAAEKKPVLSPPRAVQRPVFTGKDRTEPLNGFQKAMVKAMTAALK-IPHLGLCEEVDLTQLVRLRSELKALAESRGVKLSYMPFFIKAASLGLLQFPVLNASVDEGCQNVTYKASHN---IGLAMDTPQGLLVPSVKGVQDLSVFDVAVELNRLQALGSAGQLGTADLTGGTFTLSNIGSIGGTYAKPVILPPEVAIGALGKIQVLPRFNSRGD--VVKAHIMSISWSADHRVIDGATMCRFSNLCRSYLENPASM 478          

Query:  316 WGRKEGEAVAEGDLLAEIETDKATMSMDASDNGIMAKILVAAGTKDIPIGTPLCVI-VENESDVAAFKDFKXXXXXXXXXXXXXXXXXXXXXXXXXXXMESTKTXXXXXXXXXXXXXXGNRIFVSPYAKTLAAERNIDLATAGIAGSGPDGRIRASDL--------------DQASSPLRTVGQQ------LSSSTASYTDI--------ELSNMRKVIAQRLCISKQTIPHYYLTMDVRMNRVLEMRSKLNKKHEKSGIKISVNDFVIKASALACMRVLPCNSSWQD-----TFIRQYNQVDVSVAVATPNGLITPIVFSAHSKGLKEINNDVITLAAKARDNKLQPKEFQGGTFTVSNLGMYGISNFSAIINPPQACILAVGGSQNRLVANDKCDSGFSKATYMSVTLCCDHRVVDGAVGAQWLQEFRDNLEDPENM 1530
            W  K G+ V++ D + E+++DKA++++ +  +G++ K+        + +G+PL  I  + E D A  +D                         P    E T                G++   +P  + LA E NI L+   + G+G DGRI   D+              D+   P+  V         LS   A    +         L+  +K + + +  + + IPH  L  +V + +++ +RS+L    E  G+K+S   F IKA++L  ++    N+S  +     T+   +N   + +A+ TP GL+ P V       + ++  ++  L A     +L   +  GGTFT+SN+G  G +    +I PP+  I A+G  Q     N + D    KA  MS++   DHRV+DGA   ++    R  LE+P +M
Sbjct:   81 WYVKVGDKVSQFDSICEVQSDKASVTITSRYDGVIRKLHHDVDAIAL-VGSPLVDIETDREQDGAPEEDV---------------------VETPAVSHEHTH-----------QEIKGHKTQATPAVRRLAMENNIKLSE--VVGTGKDGRILKEDILNFLAKQTGAILPYDEVKQPVPAVTPAAEKKPVLSPPRAVQRPVFTGKDRTEPLNGFQKAMVKAMTAALK-IPHLGLCEEVDLTQLVRLRSELKALAESRGVKLSYMPFFIKAASLGLLQFPVLNASVDEGCQNVTYKASHN---IGLAMDTPQGLLVPSVKGVQDLSVFDVAVELNRLQALGSAGQLGTADLTGGTFTLSNIGSIGGTYAKPVILPPEVAIGALGKIQVLPRFNSRGD--VVKAHIMSISWSADHRVIDGATMCRFSNLCRSYLENPASM 478          

Query: 1150 GLITPIVFSAHSKGLKEINNDVITLAAKARDNKLQPKEFQGGTFTVSNLGMYGISNFSAIINPPQACILAVGGSQNRLVA 1389
            GL+ P++ +       +I   +  +  KAR N+L  ++  GGTFT+SN G++G    + IINPPQ+ IL +    +R VA
Sbjct:   25 GLVVPVLRNVGPMNFADIERAIFEMGEKARKNELAIEDMDGGTFTISNGGVFGSLFGTPIINPPQSAILGMHAINDRPVA 104          

Query:  202 VDNRISQLISRNYADYPSHKVITLPNLSPTMETGSVLSWGRKEGEAVAEGDLLAEIETDKATMSMDASDNGIMAKILVAAGTKDIPIGTPLCVIVENESDVAAFKDFKXXXX-XXXXXXXXXXXXXXXXXXXXXXXMESTKTXXXXXXXXXXXXXXGNRIFVSPYAKTLAAERNIDLATAGIAGSGPDGRIRASDLDQ----------------------ASSPLRTVGQQLSSSTASYTDIELSNMRKVIAQRLCISKQTIPHYYLTMDVRMNRVLEMRSKLNKKHEKSGIKISVNDFVIKASALACMRVLPCNSSW--QDTFIRQYNQVDVSVAVATPNGLITPIVFSAHSKGLKEINNDVITLAAKARDNKLQPKEFQGGTFTVSNLGMYGISN-FSAIINPPQACILAVGGSQNRLVANDKCDSGFSKATYMSVTLCCDHRVVDGAVGAQWLQEFRDNLEDPENM 1530
            V  R  +L  R YA YP H +I +P LSPTM  G++ +W +KEG+ ++ G+++AEIETDKA M  +  ++G +AKILV  GTKDIP+  P+ V VE+++DV AFKDFK+  S   S         EP A      P E TKT       +      G RIF SP AKT+A E+ I L    + G+GP GRI  +D++                       A+S          SSTASY D+ +S MR +I +RL  S Q IP Y ++  + ++++L++R  LN        K+S+ND ++KA  +A  RV   N+ W   +  IR++  VDVSVAVATP GL+TPIV +  +KGL +I+N++  L  +AR NKL P+EFQGGT  +SN+GM    N F++IINPPQ+ ILA+   +   V +   ++GFS    +++T   DHR +DGA GA++++E +  +E+P  M
Sbjct:   16 VLTRSLRLQLRCYASYPEHTIIGMPALSPTMTQGNLAAWTKKEGDQLSPGEVIAEIETDKAQMDFEFQEDGYLAKILVPEGTKDIPVNKPIAVYVEDKADVPAFKDFKLEDSGSDSKTSTKAQPAEPQAEKKQEAPAEETKTSAPEAKKSDVAAPQG-RIFASPLAKTIALEKGISLK--DVHGTGPRGRITKADIESYLEKSSKQSSQTSGAAAATPAAATSSTTAGSAPSPSSTASYEDVPISTMRSIIGERLLQSTQGIPSYIVSSKISISKLLKLRQSLNATANDK-YKLSINDLLVKAITVAAKRVPDANAYWLPNENVIRKFKNVDVSVAVATPTGLLTPIVKNCEAKGLSQISNEIKELVKRARINKLAPEEFQGGTICISNMGMNNAVNMFTSIINPPQSTILAIATVERVAVEDAAAENGFSFDNQVTITGTFDHRTIDGAKGAEFMKELKTVIENPLEM 480          

Query:  703 LAAERNIDLATAGIAGSGPDG----RIRASDLDQASSPLRTVGQQLSSSTAS---------YTDIELSNMRKVIAQRLCISKQTIPHYYLTMDVRMNRVLEMRSKLNKKH--EKSGIKISVNDFVIKASALACMRVLPCNSSWQDTFIRQYNQVDVSVAVATPNGLITPIVFSAHSKGLKEINNDVITLAAKARDNKLQPKEFQGGTFTVSNLGMYGISNFSAIINPPQACILAVGGSQNRLVANDKCDSGFSKATYMSVTLCCDHRVVDGAVGAQWLQEFRDNLEDPENM 1530
            +AA  N    TA    + P      +   ++  +A  P +TV +      AS          T ++++ MR  IA+RL  S+ T        +V M+ ++EMR KL K    +K+G K        KA  LA   +   N + +   I   +  D+SVAVATP GL+TP+V +A S  + +I N+++ L+ KARD KL  ++  GGTFT+SN G++G    + IIN PQ  +L + G + R V     +        M + L  DHR++DG     +L+  ++ +EDP  M
Sbjct:  174 VAARENSSEETASKKEAAPKKEAAPKKEVTEPKKADQPKKTVSKAQEPPVASNSFTPFPRTETRVKMNRMRLRIAERLKESQNTAASLTTFNEVDMSALMEMR-KLYKDEIIKKTGTKFGFMGLFSKACTLAAKDIPAVNGAIEGDQIVYRDYTDISVAVATPKGLVTPVVRNAESLSVLDIENEIVRLSHKARDGKLTLEDMTGGTFTISNGGVFGSLYGTPIINSPQTAVLGLHGVKERPVT---VNGQIVSRPMMYLALTYDHRLLDGREAVTFLKTVKELIEDPRKM 460          

Query:  259 KVITLPNLSPTMETGSVLSWGRKEGEAVAEGDLLAEIETDKATMSMDASDNGIMAKILVAAGTKDIPIGTPLCVIVENESDVAAFK 516
            K  ++P +SPTME G ++SW  K GE  + GD++ E+ETDK+ + ++A D+G +AKIL   G+KD+ +G P+  I + + D+A  K
Sbjct:   33 KTFSMPAMSPTMEKGGIVSWKYKVGEPFSAGDVILEVETDKSQIDVEALDDGKLAKILKDEGSKDVDVGEPIAYIADVDDDLATIK 118          

Query:  292 METGSVLSWGRKEGEAVAEGDLLAEIETDKATMSMDASDNGIMAKILVAAGTKDIPIGTPLCVIVENESDVAAFKDFKXXXXXXXXXXXXXXXXXXXXXXXXXXXMESTKTXXXXXXXXXXXXXXGNRIFVSPYAKTLAAERNIDLATAGIAGSGPDGRIRASDLDQASSPLRTVGQQLSSSTAS-----YTDIELSNMRKVIAQRLCISKQTIPHYYLTMDVRMNRVLEMRSKLNKKHEKSGIKISVNDFVIKASALACMRVLPCNSSWQDTFIRQYNQVDVSVAVATPNGLITPIVFSAHSKGLKEINNDVITLAAKARDNKLQPKEFQGGTFTVSNLGMYGISNFSAIINPPQACILAVGGSQNRLVANDKCDSGFSKATYMSVTLCCDHRVVDGAVGAQWLQEFRDNLEDPENM 1530
            ME G+++SW ++EG+ +AEGDLLA+IETDKATM  +  + G +AKIL+ AG+KD+PIG  LC+IV N+ DV  FK+F V  +  ++    P      AAP  PP     +    TPP AA+ P  G R+  SP AK +A ++ + L+    +G    GRI A+D+ Q ++      Q    + A      Y DI LSNMR+VIA+RL  SKQTIPHYYL++DV+M++++E+R +LN++  K   K+S+NDF++K+ ALAC +V   NSSW   FIR+Y  VDVSVAV+T NGLITPIVF A  KGL  I+ D+ +LA KAR  KLQP+EFQGGT T+SNLGM+GI NF+A+INPPQACILAVGG++ R++A++  + G+S    MSVTL CDHRVVDGAVGAQWL  F+  LE+P  M
Sbjct:    1 MEAGTLVSWEKQEGDELAEGDLLAQIETDKATMEFETPEEGFIAKILIPAGSKDVPIGKLLCIIVPNKEDVDKFKNFTVDDAEGAAESPPPPPPTKAAAPPTPPAASPPQPATPTPPAAAAAPFAGGRVMASPLAKKMAQDQGVSLSGIPGSGP--GGRITAADV-QTAASAALAAQPTPVAAAPIPGTVYEDIPLSNMRQVIAKRLLQSKQTIPHYYLSVDVKMDQLIEIRKQLNEQG-KGSYKLSINDFIVKSCALACRQVPEANSSWMGDFIRRYENVDVSVAVSTDNGLITPIVFDADKKGLSSISGDITSLAEKARAGKLQPQEFQGGTITISNLGMFGIKNFAAVINPPQACILAVGGTEKRVLADETSEKGYSVGNVMSVTLSCDHRVVDGAVGAQWLAVFKKYLENPMTM 414          

Query:  271 LPNLSPTMETGSVLSWGRKEGEAVAEGDLLAEIETDKATMSMDASDNGIMAKILVAAGTKDIPIGTPLCVIVENESDVAAFKDFKXXXXXXXXXXXXXXXXXXXXXXXXXXXMESTKTXXXXXXXXXXXXXXGNRIFVSPYAKTLAAERNIDLATAGIAGSGPDGRIRASDLDQASSPLRTVGQ----QLSSSTASYTDIELSNMRKVIAQRLCISKQTIPHYYLTMDVRMNRVLEMRSKLNKKHEKSGIKISVNDFVIKASALACMRVLP-CNSSWQDTFIRQYNQVDVSVAVATPNGLITPIVFSAHSKGLKEINNDVITLAAKARDNKLQPKEFQGGTFTVSNLGMYGISNFSAIINPPQACILAVGGSQNRLVANDKCDSGFSKATYMSVTLCCDHRVVDGAVGAQWLQEFRDNLEDP 1521
            +P LSPTMETG+++SW +KEG+ +  GD L EIETDKAT+++D  + G++AKI++  GTK++ +   + +IVE   D                 +            + PP    T         +++ P  G+ +  SP  + +     ID  ++ I  +GP GR+   D+      LR + Q      + S  ++TD+  + MR+ IA+RL  SK TIPH Y + D  M+ +L+++S L ++    G+ +SVND ++K +A+ C+R +P  N+ W    I     +D++V VAT  G+ITP++ +A    L +I+     +A +ARDNKL   EF GG+ T+SNLGM+G++ FSAIINP QA ILAVG ++  +  + +  +       ++V L CD RVVD  + ++WL+ F+  +E+P
Sbjct:    1 MPALSPTMETGTIVSWLKKEGDTIEPGDALCEIETDKATLTLDTDEQGVLAKIVIPPGTKNVKVNELIALIVEEGEDYTKV------------VVPVTGNCVVIPFDVAPPHSAGTSDEAEDEAQSSATPHKGSLLSFSPAVRYMLETNKID--SSAIPATGPHGRLLKGDI------LRFLAQGGMTPATPSPGTFTDVPNTEMRREIAKRLLKSKTTIPHVYASTDCVMDNLLQLKSHLKER----GLTVSVNDLLVKVAAV-CLRKVPEMNAVWNGKEIEYLKDIDLAVDVATDVGIITPVIRNAAYLDLSQISLVAHDIATRARDNKLHEHEFHGGSLTLSNLGMFGVTEFSAIINPLQASILAVGATRLSVSTDGQLQN------VITVKLSCDARVVDNELASRWLETFKLGIENP 391          

Query:  961 LEMRSKLNKKH-EKSGIKISVNDFVIKASALACMRVLPCNSSWQDTFIRQYNQVDVSVAVATPNGLITPIVFSAHSKGLKEINNDVITLAAKARDNKLQPKEFQGGTFTVSNLGMYGISNFSAIINPPQACILAVGGSQNRLVANDKCDSGFSKATYMSVTLCCDHRVVDGAVGAQWLQEFRDNLEDP 1521
            +EMR        +K G+K+      +KA+A A   +   N+  +D  I   + VD+SVAV+TP GL+ P++ +  S    +I   +  L  KAR+N L  ++  GGTFT+SN G++G    + IINPPQ+ IL +     R VA    +        M V L  DHR++DG     +L++ +  +EDP
Sbjct:    1 MEMRQTYKDAFFKKHGLKLGFMSAFVKAAAYALESLPVVNAVIEDNQIVYRDYVDISVAVSTPKGLVVPVLRNVESMNFADIEKAINALGEKARNNDLAIEDMDGGTFTISNGGVFGSLMGTPIINPPQSAILGMHAINERPVA---INGKIEIRPMMYVALTYDHRLIDGREAVTFLRKVKSVVEDP 185          

Query:  667 GNRIFVSPYAKTLAAERNIDLATAGIAGSGPDGRIRASDL------------------DQASSPLRTVGQQLSSSTASYTDIE-----LSNMRKVIAQRLCISKQTIPHYYLTMDVRMNRVLEMRSKLNKKHEKSGIKISVNDFVIKASALACMRVLPCNSS-----WQDTFIRQYNQVDVSVAVATPNGLITPIVFSAHSKGLKEINNDVITLAAKARDNKLQPKEFQGGTFTVSNLGMYGISNFSAIINPPQACILAVGGSQNRLVANDKCDSGFSKATYMSVTLCCDHRVVDGAVGAQWLQEFRDNLEDPENM 1530
            G ++  +P  + +A E  IDL+   + G+G DGR+   D+                    A SP        +     +  +E     +  +RK +A+ +  +   IPH+    ++ +N +++ +  +N   E+ G+K+S     IKA+++A  +    NSS      + TF   +N   + +A+ TP GL+ P V +   K + EI  ++  L       +L  ++  GGTF++SN+G  G +    ++ PP+  I A+G  Q     N   D    KA  M+V+   DHR+++GAV  ++   ++  LE+P +M
Sbjct:  101 GGKVLTTPAVRKIAMENKIDLSE--VPGTGKDGRVLKEDVVLFIHNRRAPPPAPPPQPAPAISPSAPAISPPAPVFIPHMALEDRVENIKGIRKAMAKTMT-AALNIPHFGYCDEILLNELVDFKKHINPMLEQRGVKLSFMPLFIKAASMALQQFPILNSSVDPECTKITFKAAHN---IGLAMDTPQGLVVPNVKNVQLKSVFEIAVELKRLHQLGLKGQLGTEDMTGGTFSLSNIGSIGGTYAKPVVLPPEVAIGALGKIQVLPRFNSNGD--VYKAHVMNVSWSADHRIIEGAVMCRFSNLWKSYLENPASM 408          

Query: 1078 SSWQDTFIRQYNQVDVSVAVATPNGLITPIVFSAHSKGLKEINNDVITLAAKARDNKLQPKEFQGGTFTVSNLGMYGISNFSAIINPPQACILAVGGSQNRLVA 1389
            S  +D  I   + VD+SVAV+TP GL+ P++ +  S    +I   +  L  KAR+N L  ++  GGTFT+SN G++G    + IINPPQ+ IL +     R VA
Sbjct:    1 SVIEDNQIVYRDYVDISVAVSTPKGLVVPVLRNVESMNFADIEKAINALGEKARNNDLAIEDMDGGTFTISNGGVFGSLMGTPIINPPQSAILGMHAINERPVA 104          

Query:  241 ADYPSHKVITLPNLSPTMETGSVLSWGRKEGEAVAEGDLLAEIETDKATMSMDASDNGIMAKILVAAGTKDIPIGTPLCVIVENESDVAAFKDFKXXXXXXXXXXXXXXXXXXXXXXXXXXXMESTKTXXXXXXXXXXXXXXGNRIFVSPYAKTLAAERNIDLATAGIAGSGPDGRIRASDLDQ------------------ASSPLRTVGQQLSSSTASYTDIELSNMRKVIAQRLCISKQTIPHYYLTMDVRMNRVLEMRSKLNKKHEKSGIKISVNDFVIKASALACMRVLPCNSSWQDTFIRQYNQVDVSVAVATPNGLITPIVFSAHSKGLKEINNDVITLAAKARDNKLQPKEFQGGTFTVSNLGMYGISNFSAIINPPQACILAVGGSQNRLVANDKCDSGFSKATYMSVTLCCDHRVVDGAVGAQWLQEFRDNLEDPENM 1530
            + YP H  + LP LSPTM  G+V  W +K GE + EGDLLAEIETDKAT+  +  + G +AKILV  GT+D+P+G  LC+IVE ESD+AAFKD+              A+      P  P    +      +   AA       R+F SP AK LAAE+ IDLA   ++GSGPDGR+   D++                   A++   +     ++   ++TD  +SN+RKVIAQRL  SKQTIPHYYL++DV M++VLE+R +LN++ +   IK+S+NDF+IKASALAC++V  CNSSW DT IRQ + VDVSVAV+T +GLITPIVF+AH KGL  I  DV  LAAKAR+ KLQP EFQGGTFT+SNLGM+GI NFSAIINPPQACILAVGGS+ RL+  +  + GF  A  MSVTL CDHRVVDGAVGAQWL EFR  LE P  M
Sbjct:  204 SSYPPHLKVALPALSPTMTMGTVQRWEKKVGEKLGEGDLLAEIETDKATIGFEVQEEGYLAKILVPEGTRDVPLGQTLCIIVEKESDIAAFKDY---------IETGMAEASMPPPPPAPAATAAPAATAPSSAAAAPAAPRKGRVFASPLAKKLAAEKGIDLAQ--VSGSGPDGRVTRKDIESFVPPKAAPAAAAAPSPSAAAAAPPSPAAAPAAPAGTFTDFPISNIRKVIAQRLMQSKQTIPHYYLSVDVNMDQVLELRKELNEEVKSQNIKLSLNDFIIKASALACLKVPECNSSWMDTVIRQNHVVDVSVAVSTASGLITPIVFNAHIKGLAAIGTDVAALAAKAREGKLQPHEFQGGTFTISNLGMFGIKNFSAIINPPQACILAVGGSEKRLLPAEN-EKGFDVANMMSVTLSCDHRVVDGAVGAQWLAEFRKFLEKPVTM 639          

Query:  211 RISQLISRN----YADYPSHKVITLPNLSPTMETGSVLSWGRKEGEAVAEGDLLAEIETDKATMSMDASDNGIMAKILVAAGTKDIPIGTPLCVIVENESDVAAFKD 519
            R SQL+       +   P H  + LP+LSPTM+TG++  W +KEG+ ++EG+L+AE+ETDKAT+  +  D   +AKILV  GT+DI +G+ +C+ VE+   +AAFKD
Sbjct:   61 RSSQLVGSGPNTRFYSLPPHNKVELPSLSPTMQTGTIARWEKKEGDKISEGELIAEVETDKATVGFEVMDECYLAKILVPEGTRDIAVGSVICITVESPDMIAAFKD 167          

Query:  241 ADYPSHKVITLPNLSPTMETGSVLSWGRKEGEAVAEGDLLAEIETDKATMSMDASDNGIMAKILVAAGTKDIPIGTPLCVIVENESDVAAFKDFKXXXXXXXXXXXXXXXXXXXXXXXXXXXMESTKTXXXXXXXXXXXXXXGNRIFVSPYAKTLAAERNIDLATAGIAGSGPDGRIRASDLDQ------------------ASSPLRTVGQQLSSSTASYTDIELSNMRKVIAQRLCISKQTIPHYYLTMDVRMNRVLEMRSKLNKKHEKSGIKISVNDFVIKASALACMRVLPCNSSWQDTFIRQYNQVDVSVAVATPNGLITPIVFSAHSKGLKEINNDVITLAAKARDNKLQPKEFQ 1269
            + YP H  + LP LSPTM  G+V  W +K GE + EGDLLAEIETDKAT+  +  + G +AKILV  GT+D+P+G  LC+IVE ESD+AAFKD+              A+      P  P    +      +   AA       R+F SP AK LAAE+ IDLA   ++GSGPDGR+   D++                   A++   +     ++   ++TD  +SN+RKVIAQRL  SKQTIPHYYL++DV M++VLE+R +LN++ +   IK+S+NDF+IKASALAC++V  CNSSW DT IRQ + VDVSVAV+T +GLITPIVF+AH KGL  I  DV  LAAKAR+ KLQP EFQ
Sbjct:  204 SSYPPHLKVALPALSPTMTMGTVQRWEKKVGEKLGEGDLLAEIETDKATIGFEVQEEGYLAKILVPEGTRDVPLGQTLCIIVEKESDIAAFKDY---------IETGMAEASMPPPPPAPAATAAPAATAPSSAAAAPAAPRKGRVFASPLAKKLAAEKGIDLAQ--VSGSGPDGRVTRKDIESFVPPKAAPAAAAAPSPSAAAAAPPSPAAAPAAPAGTFTDFPISNIRKVIAQRLMQSKQTIPHYYLSVDVNMDQVLELRKELNEEVKSQNIKLSLNDFIIKASALACLKVPECNSSWMDTVIRQNHVVDVSVAVSTASGLITPIVFNAHIKGLAAIGTDVAALAAKAREGKLQPHEFQ 553          

Query:  211 RISQLISRN----YADYPSHKVITLPNLSPTMETGSVLSWGRKEGEAVAEGDLLAEIETDKATMSMDASDNGIMAKILVAAGTKDIPIGTPLCVIVENESDVAAFKD 519
            R SQL+       +   P H  + LP+LSPTM+TG++  W +KEG+ ++EG+L+AE+ETDKAT+  +  D   +AKILV  GT+DI +G+ +C+ VE+   +AAFKD
Sbjct:   61 RSSQLVGSGPNTRFYSLPPHNKVELPSLSPTMQTGTIARWEKKEGDKISEGELIAEVETDKATVGFEVMDECYLAKILVPEGTRDIAVGSVICITVESPDMIAAFKD 167          

Query:  802 PLRTVGQQLSSSTASYTDIELSNMRKVIAQRLCISKQTIPHYYLTMDVRMNRVLEMRSKLNKKHEKSGIKISVNDFVIKASALACMRVLPCNSSWQDTFIRQYNQVDVSVAVATPNGLITPIVFSAHSKGLKEINNDVITLAAKARDNKLQPKEFQGGTFTVSNLGMYGISNFSAIINPPQACILAVGGSQNRLVANDKCDSGFSKATYMSVTLCCDHRVVDGAVGAQWLQEFRDNLEDPENM 1530
            PL   G+    +  ++T++  +N+R+VIAQRL  SK TIPH Y ++D  M  V+++R  L K+     IK+SVNDF+IKA+A+   ++   N +W        + V +S+AVAT  GLITPI+  A +KG++EI+     LA KARD KL P+E+QGG+F++SNLGM+GIS FSA+INPPQACILAVG S+  L   ++ D        M+VT+  D R+VD  + +++L +FR NLE P+ M
Sbjct:  283 PLSVPGK--PGAPGTFTEVPATNVRRVIAQRLTQSKTTIPHAYASIDCDMAAVIKLRKDLAKEQ----IKVSVNDFIIKAAAVTLKQMPEVNVTWSGDGPHALDSVHISIAVATDRGLITPIIRDAANKGVQEISAQAKALAQKARDGKLLPEEYQGGSFSISNLGMFGISGFSAVINPPQACILAVGTSRAELQLKEE-DQTVHTRQLMTVTMSSDGRLVDDELASRFLDQFRANLEQPQRM 518          

Query:  208 NRISQLISRNYADYPSHKVITLPNLSPTMETGSVLSWGRKEGEAVAEGDLLAEIETDKATMSMDASDNGIMAKILVAAGTKDIPIGTPLCVIVENESD 501
            +R+ Q     +A   +   + +P LSPTME G+++ W +KEGE V  GD L EIETDKA ++M++SD+GI+AKIL+  G++++P+GT + ++VE   D
Sbjct:   61 DRVRQFFHSPWALGVTPLKVQMPALSPTMEEGNIVKWLKKEGETVEAGDALCEIETDKAVVTMESSDDGILAKILMEEGSRNVPLGTLIALLVEEGQD 158          

Query:  856 IELSNMRKVIAQRLCISKQTIPHYYLTMDVRMNRVLEMRSKLNKKH-EKSGIKISVNDFVIKASALACMRVLPCNSSWQDTF--IRQYNQVDVSVAVATPNGLITPIVFSAHSKGLKEINNDVITLAAKARDNKLQPKEFQGGTFTVSNLGMYGISNFSAIINPPQACILAVGGSQNRLVANDKCDSGFSKATYMSVTLCCDHRVVDGAVGAQWLQEFRDNLEDP 1521
            ++++ MR  IAQRL  ++ T        +V M+ + EMR        +K  IK+      +KA+A A       N    DT   I   + VD+SVAVATP GL+ P++ +       +I   +  L  KAR N+L  ++  GGTFT+SN G++G    + IINPPQ+ IL + G  +R VA             M V L  DHR++DG     +L++ +  +EDP
Sbjct:  196 VKMNRMRLRIAQRLKEAQNTCAMLTTFNEVDMSNISEMRKNYKDAFLKKHNIKLGFMSAFVKAAAYALTDQPAVNGVIDDTTKEIVYRDYVDISVAVATPKGLVVPVIRNVEGMNFADIEKAINLLGEKARKNELAVEDMDGGTFTISNGGVFGSMFGTPIINPPQSAILGMHGIFDRPVA---VGGKVEIRPMMYVALTYDHRLIDGREAVTFLRKIKSVVEDP 417          

Query:  304 SVLSWGRKEGEAVAEGDLLAEIETDKATMSMDASDNGIMAKILVAAGTKDIPIGTPLCVI-VENESDVAAFKDFKXXXXXXXXXXXXXXXXXXXXXXXXXXXMESTKTXXXXXXXXXXXXXXGNRIFVSPYAKTLAAERNIDLATAGIAGSGPDGRIRASDL----------------------------------DQASSPLRTVGQQLSSSTASYTDIELSNMRKVIAQRLC---ISKQTIPHYYLTMDVRMNRVLEMRSKLNKKHEKSGIKISVNDFVIKASALACMRVLPCNSSWQD-----TFIRQYNQVDVSVAVATPNGLITPIVFSAHSKGLKEINNDVITLAAKARDNKLQPKEFQGGTFTVSNLGMYGISNFSAIINPPQACILAVGGSQ--NRLVANDKCDSGFSKATYMSVTLCCDHRVVDGAVGAQWLQEFRDNLEDPENM 1530
            +V  W  KEG+ V++ D + E+++DKA++++ +  +G++ K+        + +G PL  I  E++ DV                                      +TP             G++   +P  + LA E NI L+   + G+G DGRI   D+                                   + +SP   V      +T  +T  +++   K   + +     +   IPH+    +V ++R++ +R++L    E  G+K+S   F IKA++L  +     N+S  +     T+   +N   + +A+ T  GL+ P V +     + EI  ++  L A     +L      GGTFT+SN+G  G +    +I PP+  I A+G  Q   R  A ++      +A  M+V+   DHRV+DGA   ++   +R+ LE+P  M
Sbjct:   47 TVKEWYVKEGDKVSQFDSICEVQSDKASVTITSRYDGVIKKLYYDVDATAL-VGKPLVDIETESKEDV-------------------------------------VETPAMAREEHTHQEIKGHKTQATPAVRRLAIENNIKLSE--VVGTGKDGRILKEDIMNFLAKQTGAILPPAPVQEIQTPGPSPPSAAAPAGRPTSPSTVVKAPPPRTTPVFTGKDVTEPVKGFHKAMVKTMTAALKIPHFGYCDEVDLSRLVALRTELKPIAESRGVKLSYMPFFIKAASLGLLHFPILNASVDEDCQNITYRASHN---IGLAMDTSQGLLVPNVKNVQLLSVFEIAQELNRLQALGAAGQLGTAHLSGGTFTLSNIGSIGGTYAKPVILPPEVAIGALGKIQVLPRFGAGNQV----VRAHIMNVSWSADHRVIDGATMCRFSNLWREYLENPAAM 453          

Query:   37 MNFGSRKCFDVVKYASKYQNINRIIFYNSSKIESFQHNTPLNRKIHFIHYSRKFLVDNRISQLISRNYADYPSHKVITLPNLSPTMETGSVLSWGRKEGEAVAEGDLLAEIETDKATMSMDASDNGIMAKILVAAGTKDIPIGTPLCVIVENESDVAAFKDFKXXXXXXXXXXXXXXXXXXXXXXXXXXXMESTKTXXXXXXXXXXXXXXGNRIFVSPYAKTLAAERNIDLATAGIAGSGPDGRIRASDLDQASSPLRTVGQQLSSSTASYTDIELSNMRKVIAQRLCISKQTIPHYYLTMDVRMNRVLEMRSKLNKKHEKSGIKISVNDFVIKASALACMRVLPCNSSWQDTFIRQYNQVDVSVAVATPNGLITPIVFSAHSKGLKEINNDVITLAAKARDNKLQPKEFQGGTFTVSNLGMYGISNFSAIINPPQACILAVGGSQNRLVANDKCDSGFSKATYMSVTLCCDHRVVDGAVGAQWLQEFRDNLEDPENM 1530
            MNFGSRKCFDVVKYASKYQNINRIIFYNSSKIESFQHNTPLNR IHFIHYSRKFLVDNRISQLISRNYADYPSHKVITLPNLSPTMETGSVLSWGRKEGEAVAEGDLLAEIETDKATMSMDASDNGIMAKILVAAGTKDIPIGTPLCVIVENESDVAAFKDFKVSSSPASSGIVSPAKTEPTAAPLPPPPMESTKTPLST PVAASVPAPGNRIFVSPYAKTLAAERNIDLATAGIAGSGPDGRIRASDLDQASSPLRTVGQQLSSSTASYTDIELSNMRKVIAQRLCISKQTIPHYYLTMDVRMNRVLEMRSKLNKKHEKSGIKISVNDFVIKASALACMRVLPCNSSWQDTFIRQYNQVDVSVAVATPNGLITPIVFSAHSKGLKEINNDVITLAAKARDNKLQPKEFQGGTFTVSNLGMYGISNFSAIINPPQACILAVGGSQNRLVANDKCDSGFSKATYMSVTLCCDHRVVDGAVGAQWLQEFRDNLEDPENM
Sbjct:    1 MNFGSRKCFDVVKYASKYQNINRIIFYNSSKIESFQHNTPLNRNIHFIHYSRKFLVDNRISQLISRNYADYPSHKVITLPNLSPTMETGSVLSWGRKEGEAVAEGDLLAEIETDKATMSMDASDNGIMAKILVAAGTKDIPIGTPLCVIVENESDVAAFKDFKVSSSPASSGIVSPAKTEPTAAPLPPPPMESTKTPLSTLPVAASVPAPGNRIFVSPYAKTLAAERNIDLATAGIAGSGPDGRIRASDLDQASSPLRTVGQQLSSSTASYTDIELSNMRKVIAQRLCISKQTIPHYYLTMDVRMNRVLEMRSKLNKKHEKSGIKISVNDFVIKASALACMRVLPCNSSWQDTFIRQYNQVDVSVAVATPNGLITPIVFSAHSKGLKEINNDVITLAAKARDNKLQPKEFQGGTFTVSNLGMYGISNFSAIINPPQACILAVGGSQNRLVANDKCDSGFSKATYMSVTLCCDHRVVDGAVGAQWLQEFRDNLEDPENM 498          

Query:  823 QLSSSTASYTDIELSNMRKVIAQRLCISKQTIPHYYLTMDVRMNRVLEMRSKLNKKHEKSGIKISVNDFVIKASALACMRVLPC--NSSWQDTFIRQYNQVDVSVAVATPNGLITPIVFSAHSKGLKEINNDVITLAAKARDNKLQPKEFQGGTFTVSNLGMYGISNFSAIINPPQACILAVGGSQNRLVANDKCDSGFSKATYMSVTLCCDHRVVDGAVGAQWLQEFRDNLEDP 1521
            Q       + D+ LS+MR+ IA+R+  SK TIPH Y+T    + ++L  R  L    ++ GI +SVNDF++KA++LA +R++P   N    D  I     VD+SVAVA+ +GLITPIVF A    L  I+N +  LA +AR NKLQP+EFQGGTFT+SNLGM+GI  F+AIIN PQA ILAVG     +  +    S     T M  TLC D RVVD    AQ++   +  LE+P
Sbjct:  181 QQQQPVGQFVDLPLSSMRQTIARRMTTSKSTIPHQYVTGQADIGQLLATRKHLK---DQQGILVSVNDFIVKAASLA-LRLVPSVNNGLSSDGNITVNRSVDISVAVASDSGLITPIVFDADKLSLAAISNTIHQLAERARANKLQPQEFQGGTFTISNLGMFGIKEFTAIINSPQAAILAVGAGIGDIEHDTNNPSQPKIVTRMRFTLCSDARVVDEMASAQFVSYLKSYLENP 411          

Query:  271 LPNLSPTMETGSVLSWGRKEGEAVAEGDLLAEIETDKATMSMDASDNGIMAKILVAAGTKDIPIGTPLCVIVENESD 501
            +P+LSPTM  G ++ W +KEG+ V  GDL+ +++TDKA + M+A ++GI+AKI+    ++ I +G  + V+ + + D
Sbjct:    1 MPSLSPTMSEGGIVEWYKKEGDKVTAGDLICDVQTDKAVVGMEAEEDGILAKIIKVKDSQGIQVGDSIAVMADADED 77          

Query:  823 QLSSSTASYTDIELSNMRKVIAQRLCISKQTIPHYYLTMDVRMNRVLEMRSKLNKKHEKSGIKISVNDFVIKASALACMRVLPC--NSSWQDTFIRQYNQVDVSVAVATPNGLITPIVFSAHSKGLKEINNDVITLAAKARDNKLQPKEFQGGTFTVSNLGMYGISNFSAIINPPQACILAVGGSQNRLVANDKCDSGFSKATYMSVTLCCDHRVVDGAVGAQWLQEFRDNLEDP 1521
            Q       + D+ LS+MR+ IA+R+  SK TIPH Y+T    + ++L  R  L    ++ GI +SVNDF++KA++LA +R++P   N    D  I     VD+SVAVA+ +GLITPIVF A    L  ++N +  L  +AR NKLQP+EFQGGTFT+SNLGM+GI  F+AIIN PQA ILAVG     +  +    S     T M  TLC D RVVD    AQ++   +  LE+P
Sbjct:  181 QQQQPVGQFVDLPLSSMRQTIARRMTTSKSTIPHQYVTGQADIGQLLATRKHLK---DQQGILVSVNDFIVKAASLA-LRLVPSVNNGLSSDGNITVNRSVDISVAVASDSGLITPIVFDADKLSLAAVSNTIHQLVERARANKLQPQEFQGGTFTISNLGMFGIKEFTAIINSPQAAILAVGAGIGDIEHDTNNPSQPKIVTRMRFTLCSDARVVDEMASAQFVSYLKSYLENP 411          

Query:  271 LPNLSPTMETGSVLSWGRKEGEAVAEGDLLAEIETDKATMSMDASDNGIMAKILVAAGTKDIPIGTPLCVIVENESD 501
            +P+LSPTM  G ++ W +KEG+ V  GDL+ +++TDKA + M+A ++GI+AKI+    ++ I +G  + V+ + + D
Sbjct:    1 MPSLSPTMSEGGIVEWYKKEGDKVTAGDLICDVQTDKAVVGMEAEEDGILAKIIKVKDSQGIQVGDSIAVMADADED 77          

Query:  796 SSPLRTVGQQLSSSTASYTDIELSNMRKVIAQRLCISKQTIPHYYLTMDVRMNRVLEMRSKLNKKHEKS-GIKISVNDFVIKASALACMRVLPCNSSWQDTFIRQYNQVDVSVAVATPNGLITPIVFSAHSKGLKEINNDVITLAAKARDNKLQPKEFQGGTFTVSNLGMYGISNFSAIINPPQACILAVGGSQNRLVANDKCDSGFSKATYMSVTLCCDHRVVDGAVGAQWLQEFRDNLEDP 1521
            S P+   GQ   S + S   ++++ MR  IA+RL  ++ T        +  M+ V+ +R K  +  +K  G+K+      +K +ALA       N+      I   + +D+SVAVATP GL+ P++ +    G  EI   +  L  KAR  +L  ++  GGTFT+SN G++G    + IINPPQ+ IL +  +Q R VA    D        M + L  DHR++DG     +L++ +  +EDP
Sbjct:  189 SEPIAEPGQM--SGSRSEQRVKMNRMRLRIAERLKNAQNTCAMLTTFNECDMSAVINIRKKYQEPFQKKHGVKLGFMSAFLKGAALALADQPVVNAVIDGGDIVYRDYIDISVAVATPKGLVVPVLRNVQEMGFAEIEKGIFELGEKARLGQLAIEDMDGGTFTISNGGVFGSLMGTPIINPPQSAILGIHATQQRPVA---IDGRVEIRPMMYLALTYDHRLIDGREAVLFLRKIKAFIEDP 426          

Query:  190 RKF-LVDNRISQLISRNYADYPSHKVITLPNLSPTMETGSVLSWGRKEGEAVAEGDLLAEIETDKATMSMDASDNGIMAKILVAAGTKDIPIGTPLCVI-----VENE---SD-VAAFKDFKXXXXXXXXXXXXXXXXXXXXXXXXXXXMESTKTXXXXXXXXXXXXXXGNRIFVSPYAKTLAAERNIDLATAGIAGSGPDGRI---------------------RASDLDQASSPLRTVGQQLSSSTA---SYTD--IELSNMRKVIAQRLCISKQTIPHYYLTMDVRMNRVLEMRSKLNKKHEKSGIKISVNDFVIKASALACMRVLPCNSSWQDT---FIRQYNQVDVSVAVATPNGLITPIVFSAHSKGLKEINNDVITLAAKARDNKLQPKEFQGGTFTVSNLGMYGISNFSAIINPPQACILAVGGSQNRLVANDKCDSGFSKATYMSVTLCCDHRVVDGAVGAQWLQEFRDNLEDPE 1524
            RKF L  N   +L+  N AD           +   +    +  W  K G+ +++ + + E+++DKAT+++ +  +G++ KI        + +G PL  I     +E+E   SD V    DF++                          +E+ K               G ++  +P  + LA E NI+LA   +  +GP GRI                      +S  +Q +S L +  ++ ++ T+   S TD  + +  ++K +   +  S+ TIP +    ++ +  + +M+SK+   +  + IK++   F IKA++ A ++    N+   ++    I + +  ++  AV +P GL+ P ++   +K + EI+ ++  +  KA   KL   +   GTFT+SN+G  G +  S II  P+  I  +G  Q     N+K +     A  M ++   DHRVVDGA  A++   ++  LE PE
Sbjct:   40 RKFHLSPNLFKELVRFNLAD-----------IGEGIREVLIKEWYIKVGDRISQFNNICEVQSDKATVTITSRYDGLVKKIYYDIDETAV-VGKPLIDIELDIPMEDENVASDPVCESADFEI--------------------------LEAHK---------------GPKVSTTPSIRKLAKENNINLAF--VTPTGPHGRILKEDVMNYVNLKSQSTSHSLKESSKFEQQASSLSSSNRKSNTDTSKAESNTDKIVPIKGLQKSMMNMMNKSR-TIPDFNFCDEINITSLSKMKSKICSYN--TDIKLTYMPFFIKAASNAILQFPQLNAHLDESCENLIYKASH-NIGFAVDSPEGLVVPKIYDVQNKNIIEISQEMNDIIQKANAGKLSISDLSNGTFTLSNIGSIGGTYTSPIILSPEIVIGGIGKIQKLPRFNEKGE--VVAAQIMQISWTADHRVVDGATIARFSNLWKLYLEKPE 462