60S ribosomal protein L26

Overview
Name60S ribosomal protein L26
Smed IDSMED30013613
Length (bp)509
Neoblast Clusters

Zeng et. al., 2018




▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 



 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)




Explore this single cell expression dataset with our NB Cluster Shiny App




 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of 60S ribosomal protein L26 (SMED30013613) t-SNE clustered cells

Violin plots show distribution of expression levels for 60S ribosomal protein L26 (SMED30013613) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of 60S ribosomal protein L26 (SMED30013613) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for 60S ribosomal protein L26 (SMED30013613) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017




Hover the mouse over a column in the graph to view average RPKM values per sample.
Sort Descending | Sort Ascending | Only Non-Zero Values | Tile/Chart | Reset

Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020




SMED30013613

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 12

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
X1 cellSMED30013613SMESG000066644.1 SmedASXL_018680SmedAsxl_ww_GCZZ01PMID:26114597
Zhu et al., 2015
FACS sorted cell population asexual adult RNA-sequencing evidence
pharynxSMED30013613SMESG000066644.1 dd_Smed_v4_235_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
nervous systemSMED30013613SMESG000066644.1 dd_Smed_v4_235_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
gutSMED30013613SMESG000066644.1 dd_Smed_v4_235_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
cephalic gangliaSMED30013613SMESG000066644.1 dd_Smed_v4_235_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
muscle cellSMED30013613SMESG000066644.1 dd_Smed_v4_235_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
neoblastSMED30013613SMESG000066644.1 dd_Smed_v4_235_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
parenchymaSMED30013613SMESG000066644.1 dd_Smed_v4_235_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
parenchymal cellSMED30013613SMESG000066644.1 dd_Smed_v4_235_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
cilated neuronSMED30013613SMESG000066644.1 dd_Smed_v4_235_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
non-ciliated neuronSMED30013613SMESG000066644.1 dd_Smed_v4_235_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
neoblastSMED30013613SMESG000066644.1 dd_Smed_v6_235_0dd_Smed_v6PMID:29674432
Plass et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
BLAST of 60S ribosomal protein L26 vs. Ensembl Human
Match: RPL26 (ribosomal protein L26 [Source:HGNC Symbol;Acc:HGNC:10327])

HSP 1 Score: 163.31 bits (412), Expect = 9.922e-52
Identity = 97/141 (68.79%), Postives = 113/141 (80.14%), Query Frame = 2
Query:   62 MKFNKEITSSRRKNRQRHFNAPSHIRRKLMSSPLSKELRTKYNVRSIPVRKDDEVQIVRGHFKSSTVYKVVSCFRKKFVLHIEHVTTEKANGQTVFVGIDPSKVVIHXXXXXXXXXXXXXXXAAGKT--DNAGKYTEEKME 478
            MKFN  +TS R KNR+RHFNAPSHIRRK+MSSPLSKELR KYNVRS+P+RKDDEVQ+VRGH+K   + KVV  +RKK+V++IE V  EKANG TV VGI PSKVVI +LKLDKDRKKIL+RKA  +      GKY EE +E
Sbjct:    1 MKFNPFVTSDRSKNRKRHFNAPSHIRRKIMSSPLSKELRQKYNVRSMPIRKDDEVQVVRGHYKGQQIGKVVQVYRKKYVIYIERVQREKANGTTVHVGIHPSKVVITRLKLDKDRKKILERKAKSRQVGKEKGKYKEETIE 141          
BLAST of 60S ribosomal protein L26 vs. Ensembl Human
Match: RPL26 (ribosomal protein L26 [Source:HGNC Symbol;Acc:HGNC:10327])

HSP 1 Score: 163.31 bits (412), Expect = 9.922e-52
Identity = 97/141 (68.79%), Postives = 113/141 (80.14%), Query Frame = 2
Query:   62 MKFNKEITSSRRKNRQRHFNAPSHIRRKLMSSPLSKELRTKYNVRSIPVRKDDEVQIVRGHFKSSTVYKVVSCFRKKFVLHIEHVTTEKANGQTVFVGIDPSKVVIHXXXXXXXXXXXXXXXAAGKT--DNAGKYTEEKME 478
            MKFN  +TS R KNR+RHFNAPSHIRRK+MSSPLSKELR KYNVRS+P+RKDDEVQ+VRGH+K   + KVV  +RKK+V++IE V  EKANG TV VGI PSKVVI +LKLDKDRKKIL+RKA  +      GKY EE +E
Sbjct:    1 MKFNPFVTSDRSKNRKRHFNAPSHIRRKIMSSPLSKELRQKYNVRSMPIRKDDEVQVVRGHYKGQQIGKVVQVYRKKYVIYIERVQREKANGTTVHVGIHPSKVVITRLKLDKDRKKILERKAKSRQVGKEKGKYKEETIE 141          
BLAST of 60S ribosomal protein L26 vs. Ensembl Human
Match: RPL26 (ribosomal protein L26 [Source:HGNC Symbol;Acc:HGNC:10327])

HSP 1 Score: 163.31 bits (412), Expect = 9.922e-52
Identity = 97/141 (68.79%), Postives = 113/141 (80.14%), Query Frame = 2
Query:   62 MKFNKEITSSRRKNRQRHFNAPSHIRRKLMSSPLSKELRTKYNVRSIPVRKDDEVQIVRGHFKSSTVYKVVSCFRKKFVLHIEHVTTEKANGQTVFVGIDPSKVVIHXXXXXXXXXXXXXXXAAGKT--DNAGKYTEEKME 478
            MKFN  +TS R KNR+RHFNAPSHIRRK+MSSPLSKELR KYNVRS+P+RKDDEVQ+VRGH+K   + KVV  +RKK+V++IE V  EKANG TV VGI PSKVVI +LKLDKDRKKIL+RKA  +      GKY EE +E
Sbjct:    1 MKFNPFVTSDRSKNRKRHFNAPSHIRRKIMSSPLSKELRQKYNVRSMPIRKDDEVQVVRGHYKGQQIGKVVQVYRKKYVIYIERVQREKANGTTVHVGIHPSKVVITRLKLDKDRKKILERKAKSRQVGKEKGKYKEETIE 141          
BLAST of 60S ribosomal protein L26 vs. Ensembl Human
Match: RPL26 (ribosomal protein L26 [Source:HGNC Symbol;Acc:HGNC:10327])

HSP 1 Score: 163.31 bits (412), Expect = 9.922e-52
Identity = 97/141 (68.79%), Postives = 113/141 (80.14%), Query Frame = 2
Query:   62 MKFNKEITSSRRKNRQRHFNAPSHIRRKLMSSPLSKELRTKYNVRSIPVRKDDEVQIVRGHFKSSTVYKVVSCFRKKFVLHIEHVTTEKANGQTVFVGIDPSKVVIHXXXXXXXXXXXXXXXAAGKT--DNAGKYTEEKME 478
            MKFN  +TS R KNR+RHFNAPSHIRRK+MSSPLSKELR KYNVRS+P+RKDDEVQ+VRGH+K   + KVV  +RKK+V++IE V  EKANG TV VGI PSKVVI +LKLDKDRKKIL+RKA  +      GKY EE +E
Sbjct:    1 MKFNPFVTSDRSKNRKRHFNAPSHIRRKIMSSPLSKELRQKYNVRSMPIRKDDEVQVVRGHYKGQQIGKVVQVYRKKYVIYIERVQREKANGTTVHVGIHPSKVVITRLKLDKDRKKILERKAKSRQVGKEKGKYKEETIE 141          
BLAST of 60S ribosomal protein L26 vs. Ensembl Human
Match: RPL26L1 (ribosomal protein L26 like 1 [Source:HGNC Symbol;Acc:HGNC:17050])

HSP 1 Score: 162.54 bits (410), Expect = 2.595e-51
Identity = 96/141 (68.09%), Postives = 113/141 (80.14%), Query Frame = 2
Query:   62 MKFNKEITSSRRKNRQRHFNAPSHIRRKLMSSPLSKELRTKYNVRSIPVRKDDEVQIVRGHFKSSTVYKVVSCFRKKFVLHIEHVTTEKANGQTVFVGIDPSKVVIHXXXXXXXXXXXXXXXAAGKT--DNAGKYTEEKME 478
            MKFN  +TS R KNR+RHFNAPSH+RRK+MSSPLSKELR KYNVRS+P+RKDDEVQ+VRGH+K   + KVV  +RKK+V++IE V  EKANG TV VGI PSKVVI +LKLDKDRKKIL+RKA  +      GKY EE +E
Sbjct:    1 MKFNPFVTSDRSKNRKRHFNAPSHVRRKIMSSPLSKELRQKYNVRSMPIRKDDEVQVVRGHYKGQQIGKVVQVYRKKYVIYIERVQREKANGTTVHVGIHPSKVVITRLKLDKDRKKILERKAKSRQVGKEKGKYKEELIE 141          
BLAST of 60S ribosomal protein L26 vs. Ensembl Celegans
Match: rpl-26 (60S ribosomal protein L26 [Source:UniProtKB/Swiss-Prot;Acc:Q19869])

HSP 1 Score: 131.339 bits (329), Expect = 1.741e-39
Identity = 78/140 (55.71%), Postives = 108/140 (77.14%), Query Frame = 2
Query:   62 MKFNKEITSSRRKNRQRHFNAPSHIRRKLMSSPLSKELRTKYNVRSIPVRKDDEVQIVRGHFKSSTVYKVVSCFRKKFVLHIEHVTTEKANGQTVFVGIDPSKVVIHXXXXXXXXXXXXXXXAAGKTDNA----GKYTEE 469
            MK N  ++S   K+R+ HFNAPSH RR++MS+PL+KELRTK+ +R+IP+R DDEV ++RG  K +T  +V+ C+RKKFV+HI+ +T EKANG TV +GI PSKV I KLKLDKDR+ +++RKAAG++       GK+T+E
Sbjct:    1 MKVNPFVSSDSGKSRKAHFNAPSHERRRIMSAPLTKELRTKHGIRAIPIRTDDEVVVMRGRHKGNT-GRVLRCYRKKFVIHIDKITREKANGSTVHIGIHPSKVAITKLKLDKDRRALVERKAAGRSRVTGILKGKHTDE 139          
BLAST of 60S ribosomal protein L26 vs. Ensembl Celegans
Match: rpl-26 (60S ribosomal protein L26 [Source:UniProtKB/Swiss-Prot;Acc:Q19869])

HSP 1 Score: 126.331 bits (316), Expect = 5.234e-38
Identity = 60/104 (57.69%), Postives = 82/104 (78.85%), Query Frame = 2
Query:   62 MKFNKEITSSRRKNRQRHFNAPSHIRRKLMSSPLSKELRTKYNVRSIPVRKDDEVQIVRGHFKSSTVYKVVSCFRKKFVLHIEHVTTEKANGQTVFVGIDPSKV 373
            MK N  ++S   K+R+ HFNAPSH RR++MS+PL+KELRTK+ +R+IP+R DDEV ++RG  K +T  +V+ C+RKKFV+HI+ +T EKANG TV +GI PSKV
Sbjct:    1 MKVNPFVSSDSGKSRKAHFNAPSHERRRIMSAPLTKELRTKHGIRAIPIRTDDEVVVMRGRHKGNT-GRVLRCYRKKFVIHIDKITREKANGSTVHIGIHPSKV 103          
BLAST of 60S ribosomal protein L26 vs. Ensembl Celegans
Match: rpl-26 (60S ribosomal protein L26 [Source:UniProtKB/Swiss-Prot;Acc:Q19869])

HSP 1 Score: 125.946 bits (315), Expect = 5.824e-38
Identity = 60/104 (57.69%), Postives = 82/104 (78.85%), Query Frame = 2
Query:   62 MKFNKEITSSRRKNRQRHFNAPSHIRRKLMSSPLSKELRTKYNVRSIPVRKDDEVQIVRGHFKSSTVYKVVSCFRKKFVLHIEHVTTEKANGQTVFVGIDPSKV 373
            MK N  ++S   K+R+ HFNAPSH RR++MS+PL+KELRTK+ +R+IP+R DDEV ++RG  K +T  +V+ C+RKKFV+HI+ +T EKANG TV +GI PSKV
Sbjct:    1 MKVNPFVSSDSGKSRKAHFNAPSHERRRIMSAPLTKELRTKHGIRAIPIRTDDEVVVMRGRHKGNT-GRVLRCYRKKFVIHIDKITREKANGSTVHIGIHPSKV 103          
BLAST of 60S ribosomal protein L26 vs. Ensembl Fly
Match: RpL26 (gene:FBgn0036825 transcript:FBtr0333709)

HSP 1 Score: 160.614 bits (405), Expect = 7.173e-51
Identity = 94/149 (63.09%), Postives = 116/149 (77.85%), Query Frame = 2
Query:   62 MKFNKEITSSRRKNRQRHFNAPSHIRRKLMSSPLSKELRTKYNVRSIPVRKDDEVQIVRGHFKSSTVYKVVSCFRKKFVLHIEHVTTEKANGQTVFVGIDPSKVVIHXXXXXXXXXXXXXXXAAGKT----DNAGKYTEE----KMETA 484
            MK N  ++SSRRKNR+RHF APSHIRR+LMS+PLSKELR KYNVRS+P+R+DDEVQ++RGHFK + V KVV  +RKKFV+++E +  E ANG  V+VGI PSKV+I KLKLDKDRK IL+R+  G+      + GKYTEE     META
Sbjct:    1 MKQNPFVSSSRRKNRKRHFQAPSHIRRRLMSAPLSKELRQKYNVRSMPIRRDDEVQVIRGHFKGNQVGKVVQAYRKKFVVYVEKIQRENANGTNVYVGIHPSKVLIVKLKLDKDRKAILERRGKGRLAALGKDKGKYTEETAAQPMETA 149          
BLAST of 60S ribosomal protein L26 vs. Ensembl Fly
Match: RpL26 (gene:FBgn0036825 transcript:FBtr0347494)

HSP 1 Score: 160.614 bits (405), Expect = 7.173e-51
Identity = 94/149 (63.09%), Postives = 116/149 (77.85%), Query Frame = 2
Query:   62 MKFNKEITSSRRKNRQRHFNAPSHIRRKLMSSPLSKELRTKYNVRSIPVRKDDEVQIVRGHFKSSTVYKVVSCFRKKFVLHIEHVTTEKANGQTVFVGIDPSKVVIHXXXXXXXXXXXXXXXAAGKT----DNAGKYTEE----KMETA 484
            MK N  ++SSRRKNR+RHF APSHIRR+LMS+PLSKELR KYNVRS+P+R+DDEVQ++RGHFK + V KVV  +RKKFV+++E +  E ANG  V+VGI PSKV+I KLKLDKDRK IL+R+  G+      + GKYTEE     META
Sbjct:    1 MKQNPFVSSSRRKNRKRHFQAPSHIRRRLMSAPLSKELRQKYNVRSMPIRRDDEVQVIRGHFKGNQVGKVVQAYRKKFVVYVEKIQRENANGTNVYVGIHPSKVLIVKLKLDKDRKAILERRGKGRLAALGKDKGKYTEETAAQPMETA 149          
BLAST of 60S ribosomal protein L26 vs. Ensembl Fly
Match: RpL26 (gene:FBgn0036825 transcript:FBtr0075066)

HSP 1 Score: 160.614 bits (405), Expect = 7.173e-51
Identity = 94/149 (63.09%), Postives = 116/149 (77.85%), Query Frame = 2
Query:   62 MKFNKEITSSRRKNRQRHFNAPSHIRRKLMSSPLSKELRTKYNVRSIPVRKDDEVQIVRGHFKSSTVYKVVSCFRKKFVLHIEHVTTEKANGQTVFVGIDPSKVVIHXXXXXXXXXXXXXXXAAGKT----DNAGKYTEE----KMETA 484
            MK N  ++SSRRKNR+RHF APSHIRR+LMS+PLSKELR KYNVRS+P+R+DDEVQ++RGHFK + V KVV  +RKKFV+++E +  E ANG  V+VGI PSKV+I KLKLDKDRK IL+R+  G+      + GKYTEE     META
Sbjct:    1 MKQNPFVSSSRRKNRKRHFQAPSHIRRRLMSAPLSKELRQKYNVRSMPIRRDDEVQVIRGHFKGNQVGKVVQAYRKKFVVYVEKIQRENANGTNVYVGIHPSKVLIVKLKLDKDRKAILERRGKGRLAALGKDKGKYTEETAAQPMETA 149          
BLAST of 60S ribosomal protein L26 vs. Ensembl Zebrafish
Match: rpl26 (ribosomal protein L26 [Source:ZFIN;Acc:ZDB-GENE-040426-2117])

HSP 1 Score: 169.474 bits (428), Expect = 2.763e-54
Identity = 99/141 (70.21%), Postives = 115/141 (81.56%), Query Frame = 2
Query:   62 MKFNKEITSSRRKNRQRHFNAPSHIRRKLMSSPLSKELRTKYNVRSIPVRKDDEVQIVRGHFKSSTVYKVVSCFRKKFVLHIEHVTTEKANGQTVFVGIDPSKVVIHXXXXXXXXXXXXXXXAAGKTD--NAGKYTEEKME 478
            MK N  +TSSRRKNR+RHFNAPSHIRRK+MSSPLSKELR KYNVRS+P+RKDDEVQ+VRGH+K   + KVV  +RKK+V++IE V  EKANG TV VGI PSKVVI +LKLDKDRKKIL+RKA  + D    GKY EE +E
Sbjct:    1 MKLNTFVTSSRRKNRKRHFNAPSHIRRKIMSSPLSKELRQKYNVRSMPIRKDDEVQVVRGHYKGQQIGKVVQVYRKKYVIYIERVQREKANGTTVHVGIHPSKVVITRLKLDKDRKKILERKAKSRQDIKEKGKYKEETIE 141          
BLAST of 60S ribosomal protein L26 vs. Ensembl Zebrafish
Match: atp6v0e1 (ATPase H+ transporting V0 subunit e1 [Source:ZFIN;Acc:ZDB-GENE-041010-133])

HSP 1 Score: 169.474 bits (428), Expect = 2.763e-54
Identity = 99/141 (70.21%), Postives = 115/141 (81.56%), Query Frame = 2
Query:   62 MKFNKEITSSRRKNRQRHFNAPSHIRRKLMSSPLSKELRTKYNVRSIPVRKDDEVQIVRGHFKSSTVYKVVSCFRKKFVLHIEHVTTEKANGQTVFVGIDPSKVVIHXXXXXXXXXXXXXXXAAGKTD--NAGKYTEEKME 478
            MK N  +TSSRRKNR+RHFNAPSHIRRK+MSSPLSKELR KYNVRS+P+RKDDEVQ+VRGH+K   + KVV  +RKK+V++IE V  EKANG TV VGI PSKVVI +LKLDKDRKKIL+RKA  + D    GKY EE +E
Sbjct:    1 MKLNTFVTSSRRKNRKRHFNAPSHIRRKIMSSPLSKELRQKYNVRSMPIRKDDEVQVVRGHYKGQQIGKVVQVYRKKYVIYIERVQREKANGTTVHVGIHPSKVVITRLKLDKDRKKILERKAKSRQDIKEKGKYKEETIE 141          
BLAST of 60S ribosomal protein L26 vs. Ensembl Xenopus
Match: rpl26 (ribosomal protein L26 [Source:NCBI gene;Acc:448683])

HSP 1 Score: 158.688 bits (400), Expect = 7.105e-50
Identity = 94/141 (66.67%), Postives = 113/141 (80.14%), Query Frame = 2
Query:   62 MKFNKEITSSRRKNRQRHFNAPSHIRRKLMSSPLSKELRTKYNVRSIPVRKDDEVQIVRGHFKSSTVYKVVSCFRKKFVLHIEHVTTEKANGQTVFVGIDPSKVVIHXXXXXXXXXXXXXXXAAGKT--DNAGKYTEEKME 478
            MKF+  +TS R KNR+RHFNAPSH+RRK+MSSPLSKELR KY+VRS+P+RKDDEVQ+VRGH+K   + KVV  +RKK+V++IE V  EKANG TV VGI PSKVVI +LKLDKDRKKIL+RKA  +      GKY EE +E
Sbjct:    1 MKFSPFVTSDRSKNRKRHFNAPSHVRRKIMSSPLSKELRQKYSVRSMPIRKDDEVQVVRGHYKGQQIGKVVQVYRKKYVIYIERVQREKANGTTVHVGIHPSKVVITRLKLDKDRKKILERKAKSRQVGKEKGKYKEETIE 141          
BLAST of 60S ribosomal protein L26 vs. Ensembl Mouse
Match: Rpl26 (ribosomal protein L26 [Source:MGI Symbol;Acc:MGI:106022])

HSP 1 Score: 163.31 bits (412), Expect = 6.812e-52
Identity = 97/141 (68.79%), Postives = 113/141 (80.14%), Query Frame = 2
Query:   62 MKFNKEITSSRRKNRQRHFNAPSHIRRKLMSSPLSKELRTKYNVRSIPVRKDDEVQIVRGHFKSSTVYKVVSCFRKKFVLHIEHVTTEKANGQTVFVGIDPSKVVIHXXXXXXXXXXXXXXXAAGKT--DNAGKYTEEKME 478
            MKFN  +TS R KNR+RHFNAPSHIRRK+MSSPLSKELR KYNVRS+P+RKDDEVQ+VRGH+K   + KVV  +RKK+V++IE V  EKANG TV VGI PSKVVI +LKLDKDRKKIL+RKA  +      GKY EE +E
Sbjct:    1 MKFNPFVTSDRSKNRKRHFNAPSHIRRKIMSSPLSKELRQKYNVRSMPIRKDDEVQVVRGHYKGQQIGKVVQVYRKKYVIYIERVQREKANGTTVHVGIHPSKVVITRLKLDKDRKKILERKAKSRQVGKEKGKYKEETIE 141          
BLAST of 60S ribosomal protein L26 vs. Ensembl Mouse
Match: Rpl26 (ribosomal protein L26 [Source:MGI Symbol;Acc:MGI:106022])

HSP 1 Score: 163.31 bits (412), Expect = 6.812e-52
Identity = 97/141 (68.79%), Postives = 113/141 (80.14%), Query Frame = 2
Query:   62 MKFNKEITSSRRKNRQRHFNAPSHIRRKLMSSPLSKELRTKYNVRSIPVRKDDEVQIVRGHFKSSTVYKVVSCFRKKFVLHIEHVTTEKANGQTVFVGIDPSKVVIHXXXXXXXXXXXXXXXAAGKT--DNAGKYTEEKME 478
            MKFN  +TS R KNR+RHFNAPSHIRRK+MSSPLSKELR KYNVRS+P+RKDDEVQ+VRGH+K   + KVV  +RKK+V++IE V  EKANG TV VGI PSKVVI +LKLDKDRKKIL+RKA  +      GKY EE +E
Sbjct:    1 MKFNPFVTSDRSKNRKRHFNAPSHIRRKIMSSPLSKELRQKYNVRSMPIRKDDEVQVVRGHYKGQQIGKVVQVYRKKYVIYIERVQREKANGTTVHVGIHPSKVVITRLKLDKDRKKILERKAKSRQVGKEKGKYKEETIE 141          
BLAST of 60S ribosomal protein L26 vs. Ensembl Mouse
Match: Rpl26 (ribosomal protein L26 [Source:MGI Symbol;Acc:MGI:106022])

HSP 1 Score: 154.836 bits (390), Expect = 4.703e-49
Identity = 74/103 (71.84%), Postives = 86/103 (83.50%), Query Frame = 2
Query:   62 MKFNKEITSSRRKNRQRHFNAPSHIRRKLMSSPLSKELRTKYNVRSIPVRKDDEVQIVRGHFKSSTVYKVVSCFRKKFVLHIEHVTTEKANGQTVFVGIDPSK 370
            MKFN  +TS R KNR+RHFNAPSHIRRK+MSSPLSKELR KYNVRS+P+RKDDEVQ+VRGH+K   + KVV  +RKK+V++IE V  EKANG TV VGI PSK
Sbjct:    1 MKFNPFVTSDRSKNRKRHFNAPSHIRRKIMSSPLSKELRQKYNVRSMPIRKDDEVQVVRGHYKGQQIGKVVQVYRKKYVIYIERVQREKANGTTVHVGIHPSK 103          
BLAST of 60S ribosomal protein L26 vs. Ensembl Mouse
Match: Rpl26 (ribosomal protein L26 [Source:MGI Symbol;Acc:MGI:106022])

HSP 1 Score: 155.221 bits (391), Expect = 1.353e-48
Identity = 96/141 (68.09%), Postives = 111/141 (78.72%), Query Frame = 2
Query:   62 MKFNKEITSSRRKNRQRHFNAPSHIRRKLMSSPLSKELRTKYNVRSIPVRKDDEVQIVRGHFKSSTVYKVVSCFRKKFVLHIEHVTTEKANGQTVFVGIDPSKVVIHXXXXXXXXXXXXXXXAAGKT--DNAGKYTEEKME 478
            MKFN  +TS R KNR+RHFNAPSHIRRK+MSSPLSKELR KYNVRS+P+RKDDEV  VRGH+K   + KVV  +RKK+V++IE V  EKANG TV VGI PSKVVI +LKLDKDRKKIL+RKA  +      GKY EE +E
Sbjct:    1 MKFNPFVTSDRSKNRKRHFNAPSHIRRKIMSSPLSKELRQKYNVRSMPIRKDDEV--VRGHYKGQQIGKVVQVYRKKYVIYIERVQREKANGTTVHVGIHPSKVVITRLKLDKDRKKILERKAKSRQVGKEKGKYKEETIE 139          
BLAST of 60S ribosomal protein L26 vs. UniProt/SwissProt
Match: sp|Q95WA0|RL26_LITLI (60S ribosomal protein L26 OS=Littorina littorea OX=31216 GN=RPL26 PE=2 SV=1)

HSP 1 Score: 172.17 bits (435), Expect = 1.482e-54
Identity = 99/144 (68.75%), Postives = 116/144 (80.56%), Query Frame = 2
Query:   62 MKFNKEITSSRRKNRQRHFNAPSHIRRKLMSSPLSKELRTKYNVRSIPVRKDDEVQIVRGHFKSSTVYKVVSCFRKKFVLHIEHVTTEKANGQTVFVGIDPSKVVIHXXXXXXXXXXXXXXXA---AGKTDNAGKYTEEKMETA 484
            MKFNK ++S R KNR+RHFNAPSH+RRK+MSSP+SKELR KYN RS+P+RKDDEVQ+VRGHFK   V KVV  +RKKFV+HIE +  EKANG TV+VGI PSKV+I KLK+DKDRK+ILD KA   A      GKYTEE MET+
Sbjct:    1 MKFNKMVSSDRGKNRKRHFNAPSHMRRKIMSSPMSKELRQKYNCRSMPIRKDDEVQVVRGHFKGQQVGKVVQVYRKKFVVHIERIQREKANGATVYVGIHPSKVLIVKLKMDKDRKRILDNKAKSRAKALAEKGKYTEETMETS 144          
BLAST of 60S ribosomal protein L26 vs. UniProt/SwissProt
Match: sp|P12749|RL26_RAT (60S ribosomal protein L26 OS=Rattus norvegicus OX=10116 GN=Rpl26 PE=1 SV=1)

HSP 1 Score: 163.696 bits (413), Expect = 3.323e-51
Identity = 97/141 (68.79%), Postives = 113/141 (80.14%), Query Frame = 2
Query:   62 MKFNKEITSSRRKNRQRHFNAPSHIRRKLMSSPLSKELRTKYNVRSIPVRKDDEVQIVRGHFKSSTVYKVVSCFRKKFVLHIEHVTTEKANGQTVFVGIDPSKVVIHXXXXXXXXXXXXXXXAAGKT--DNAGKYTEEKME 478
            MKFN  +TS R KNR+RHFNAPSHIRRK+MSSPLSKELR KYNVRS+P+RKDDEVQ+VRGH+K   + KVV  +RKK+V++IE V  EKANG TV VGI PSKVVI +LKLDKDRKKIL+RKA  +      GKY EE +E
Sbjct:    1 MKFNPFVTSDRSKNRKRHFNAPSHIRRKIMSSPLSKELRQKYNVRSMPIRKDDEVQVVRGHYKGQQIGKVVQVYRKKYVIYIERVQREKANGTTVHVGIRPSKVVITRLKLDKDRKKILERKAKSRQVGKEKGKYKEETIE 141          
BLAST of 60S ribosomal protein L26 vs. UniProt/SwissProt
Match: sp|P61255|RL26_MOUSE (60S ribosomal protein L26 OS=Mus musculus OX=10090 GN=Rpl26 PE=1 SV=1)

HSP 1 Score: 163.31 bits (412), Expect = 4.765e-51
Identity = 97/141 (68.79%), Postives = 113/141 (80.14%), Query Frame = 2
Query:   62 MKFNKEITSSRRKNRQRHFNAPSHIRRKLMSSPLSKELRTKYNVRSIPVRKDDEVQIVRGHFKSSTVYKVVSCFRKKFVLHIEHVTTEKANGQTVFVGIDPSKVVIHXXXXXXXXXXXXXXXAAGKT--DNAGKYTEEKME 478
            MKFN  +TS R KNR+RHFNAPSHIRRK+MSSPLSKELR KYNVRS+P+RKDDEVQ+VRGH+K   + KVV  +RKK+V++IE V  EKANG TV VGI PSKVVI +LKLDKDRKKIL+RKA  +      GKY EE +E
Sbjct:    1 MKFNPFVTSDRSKNRKRHFNAPSHIRRKIMSSPLSKELRQKYNVRSMPIRKDDEVQVVRGHYKGQQIGKVVQVYRKKYVIYIERVQREKANGTTVHVGIHPSKVVITRLKLDKDRKKILERKAKSRQVGKEKGKYKEETIE 141          
BLAST of 60S ribosomal protein L26 vs. UniProt/SwissProt
Match: sp|P61256|RL26_MACFA (60S ribosomal protein L26 OS=Macaca fascicularis OX=9541 GN=RPL26 PE=2 SV=1)

HSP 1 Score: 163.31 bits (412), Expect = 4.765e-51
Identity = 97/141 (68.79%), Postives = 113/141 (80.14%), Query Frame = 2
Query:   62 MKFNKEITSSRRKNRQRHFNAPSHIRRKLMSSPLSKELRTKYNVRSIPVRKDDEVQIVRGHFKSSTVYKVVSCFRKKFVLHIEHVTTEKANGQTVFVGIDPSKVVIHXXXXXXXXXXXXXXXAAGKT--DNAGKYTEEKME 478
            MKFN  +TS R KNR+RHFNAPSHIRRK+MSSPLSKELR KYNVRS+P+RKDDEVQ+VRGH+K   + KVV  +RKK+V++IE V  EKANG TV VGI PSKVVI +LKLDKDRKKIL+RKA  +      GKY EE +E
Sbjct:    1 MKFNPFVTSDRSKNRKRHFNAPSHIRRKIMSSPLSKELRQKYNVRSMPIRKDDEVQVVRGHYKGQQIGKVVQVYRKKYVIYIERVQREKANGTTVHVGIHPSKVVITRLKLDKDRKKILERKAKSRQVGKEKGKYKEETIE 141          
BLAST of 60S ribosomal protein L26 vs. UniProt/SwissProt
Match: sp|P61254|RL26_HUMAN (60S ribosomal protein L26 OS=Homo sapiens OX=9606 GN=RPL26 PE=1 SV=1)

HSP 1 Score: 163.31 bits (412), Expect = 4.765e-51
Identity = 97/141 (68.79%), Postives = 113/141 (80.14%), Query Frame = 2
Query:   62 MKFNKEITSSRRKNRQRHFNAPSHIRRKLMSSPLSKELRTKYNVRSIPVRKDDEVQIVRGHFKSSTVYKVVSCFRKKFVLHIEHVTTEKANGQTVFVGIDPSKVVIHXXXXXXXXXXXXXXXAAGKT--DNAGKYTEEKME 478
            MKFN  +TS R KNR+RHFNAPSHIRRK+MSSPLSKELR KYNVRS+P+RKDDEVQ+VRGH+K   + KVV  +RKK+V++IE V  EKANG TV VGI PSKVVI +LKLDKDRKKIL+RKA  +      GKY EE +E
Sbjct:    1 MKFNPFVTSDRSKNRKRHFNAPSHIRRKIMSSPLSKELRQKYNVRSMPIRKDDEVQVVRGHYKGQQIGKVVQVYRKKYVIYIERVQREKANGTTVHVGIHPSKVVITRLKLDKDRKKILERKAKSRQVGKEKGKYKEETIE 141          
BLAST of 60S ribosomal protein L26 vs. TrEMBL
Match: A8UFE0 (Ribosomal protein rpl26 OS=Arenicola marina OX=6344 PE=2 SV=1)

HSP 1 Score: 174.866 bits (442), Expect = 4.104e-53
Identity = 99/142 (69.72%), Postives = 119/142 (83.80%), Query Frame = 2
Query:   62 MKFNKEITSSRRKNRQRHFNAPSHIRRKLMSSPLSKELRTKYNVRSIPVRKDDEVQIVRGHFKSSTVYKVVSCFRKKFVLHIEHVTTEKANGQTVFVGIDPSKVVIHXXXXXXXXXXXXXXXAAGKTDNAGKYTEEK-META 484
            MKFNK ++SSRRKNR+RHFNAPSHIRRK+MSSPLSKELR KYNVRSIP+RKDDEVQ+VRGH+K   V KVV  +RKKFV++IE +  EKANG TV VGI PSKVV+ KLK+DKDR+ IL+RK+  +  + GK+TEE  MET+
Sbjct:    1 MKFNKMVSSSRRKNRKRHFNAPSHIRRKIMSSPLSKELRQKYNVRSIPIRKDDEVQVVRGHYKGQQVGKVVQVYRKKFVIYIERIQREKANGATVHVGIHPSKVVVVKLKMDKDRRSILERKSKAREMDKGKHTEESIMETS 142          
BLAST of 60S ribosomal protein L26 vs. TrEMBL
Match: A0A1Y1N2W9 (KOW domain-containing protein OS=Photinus pyralis OX=7054 GN=PPYR_05156 PE=3 SV=1)

HSP 1 Score: 173.326 bits (438), Expect = 1.863e-52
Identity = 98/145 (67.59%), Postives = 117/145 (80.69%), Query Frame = 2
Query:   62 MKFNKEITSSRRKNRQRHFNAPSHIRRKLMSSPLSKELRTKYNVRSIPVRKDDEVQIVRGHFKSSTVYKVVSCFRKKFVLHIEHVTTEKANGQTVFVGIDPSKVVIHXXXXXXXXXXXXXXXAAGKT----DNAGKYTEEKMETA 484
            MK NK +T+SRRKNR+RHF+APSHIRR+LMSSPLSKELR KYNVRSIP+RKDDEVQ+VRGH+K   V KVV  +RKKFV++IE +  EKANG +V+VGI PSKVVI KLK+DKDRK I+DR+A G+      + GKYTEE    A
Sbjct:    1 MKLNKLVTASRRKNRKRHFSAPSHIRRRLMSSPLSKELRQKYNVRSIPIRKDDEVQVVRGHYKGQQVGKVVQVYRKKFVIYIERIQREKANGASVYVGIHPSKVVIVKLKMDKDRKNIIDRRAKGRLAALGKDKGKYTEESAAAA 145          
BLAST of 60S ribosomal protein L26 vs. TrEMBL
Match: A0A267EK55 (KOW domain-containing protein (Fragment) OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig026409g1 PE=3 SV=1)

HSP 1 Score: 172.17 bits (435), Expect = 5.389e-52
Identity = 95/138 (68.84%), Postives = 117/138 (84.78%), Query Frame = 2
Query:   59 KMKFNKEITSSRRKNRQRHFNAPSHIRRKLMSSPLSKELRTKYNVRSIPVRKDDEVQIVRGHFKSSTVYKVVSCFRKKFVLHIEHVTTEKANGQTVFVGIDPSKVVIHXXXXXXXXXXXXXXXAAGKTDNA--GKYTE 466
            +MKFNK +TSS+RKNRQR+FNAPSHIRRKLMS+PLSKELRTKYNVRS+P+RKDDEVQ+VRGH K +   KVV+ +R K+V+H+E +  EKANG TV+V + PSKVVI KLKLD+DR+ +LDRKAAG+   A  GKY+E
Sbjct:    2 EMKFNKSVTSSKRKNRQRYFNAPSHIRRKLMSAPLSKELRTKYNVRSMPIRKDDEVQLVRGHHKGTQTGKVVAVYRSKYVIHVERIQREKANGATVYVNLHPSKVVITKLKLDRDRRGLLDRKAAGRARGAEKGKYSE 139          
BLAST of 60S ribosomal protein L26 vs. TrEMBL
Match: A0A481SWK9 (60S ribosomal protein L26 OS=Nicoletia phytophila OX=1350298 PE=2 SV=1)

HSP 1 Score: 172.17 bits (435), Expect = 5.818e-52
Identity = 99/147 (67.35%), Postives = 119/147 (80.95%), Query Frame = 2
Query:   62 MKFNKEITSSRRKNRQRHFNAPSHIRRKLMSSPLSKELRTKYNVRSIPVRKDDEVQIVRGHFKSSTVYKVVSCFRKKFVLHIEHVTTEKANGQTVFVGIDPSKVVIHXXXXXXXXXXXXXXXAAGKT----DNAGKYTEEK--META 484
            MK NK +TS+RRKNR+RHF APSHIRRKLMSSPLSKELR KYNVRS+P+R+DDEVQ+VRGH+K   V KVV  +RKKFV++IE +  EKANG  V+VGI PSKVVI KLK+DKDRKKI++R+A G+      + GKYTEE   MET+
Sbjct:    1 MKLNKMVTSARRKNRKRHFTAPSHIRRKLMSSPLSKELRQKYNVRSMPIRRDDEVQVVRGHYKGQQVGKVVQVYRKKFVIYIERIQREKANGANVYVGIHPSKVVIVKLKMDKDRKKIIERRAKGRLAALGKDKGKYTEESTAMETS 147          
BLAST of 60S ribosomal protein L26 vs. TrEMBL
Match: B0Z9M7 (Ribosomal protein rpl26 OS=Lineus viridis OX=56195 PE=2 SV=1)

HSP 1 Score: 171.785 bits (434), Expect = 5.908e-52
Identity = 103/143 (72.03%), Postives = 120/143 (83.92%), Query Frame = 2
Query:   62 MKFNKEITSSRRKNRQRHFNAPSHIRRKLMSSPLSKELRTKYNVRSIPVRKDDEVQIVRGHFKSSTVYKVVSCFRKKFVLHIEHVTTEKANGQTVFVGIDPSKVVIHXXXXXXXXXXXXXXXAAGKTD-NAGKYTEEK-META 484
            MKFNK +TSSRRKNR+R+FNAPSH+RRKLMSSPLSKELR KYNVRS+PVRKDDEVQ+VRGHFK   V K+V  +RKKFV+HIE +  +KANG TV VGI PSKVVI KLKLDKDRK+ILDRK+  +   + GK+TEE  MET+
Sbjct:    1 MKFNKMVTSSRRKNRKRYFNAPSHVRRKLMSSPLSKELRQKYNVRSMPVRKDDEVQVVRGHFKGQQVGKIVQVYRKKFVIHIERIQRDKANGATVNVGIHPSKVVIVKLKLDKDRKRILDRKSKSRASADKGKHTEESIMETS 143          
BLAST of 60S ribosomal protein L26 vs. Ensembl Cavefish
Match: rpl26 (60S ribosomal protein L26 [Source:NCBI gene;Acc:103040128])

HSP 1 Score: 168.318 bits (425), Expect = 7.708e-54
Identity = 98/141 (69.50%), Postives = 115/141 (81.56%), Query Frame = 2
Query:   62 MKFNKEITSSRRKNRQRHFNAPSHIRRKLMSSPLSKELRTKYNVRSIPVRKDDEVQIVRGHFKSSTVYKVVSCFRKKFVLHIEHVTTEKANGQTVFVGIDPSKVVIHXXXXXXXXXXXXXXXAAGKTDN--AGKYTEEKME 478
            MK N  +TSSRRKNR+RHFNAPSH+RRK+MSSPLSKELR KYNVRS+P+RKDDEVQ+VRGH+K   + KVV  +RKK+V++IE V  EKANG TV VGI PSKVVI +LKLDKDRKKIL+RKA  + D    GKY EE +E
Sbjct:    1 MKINPFVTSSRRKNRKRHFNAPSHVRRKIMSSPLSKELRQKYNVRSMPIRKDDEVQVVRGHYKGQQIGKVVQVYRKKYVIYIERVQREKANGTTVHVGIHPSKVVITRLKLDKDRKKILERKAKSRQDGKEKGKYKEETIE 141          
BLAST of 60S ribosomal protein L26 vs. Ensembl Sea Lamprey
Match: rpl26 (ribosomal protein L26 [Source:ZFIN;Acc:ZDB-GENE-040426-2117])

HSP 1 Score: 162.155 bits (409), Expect = 3.166e-52
Identity = 94/141 (66.67%), Postives = 114/141 (80.85%), Query Frame = 2
Query:   62 MKFNKEITSSRRKNRQRHFNAPSHIRRKLMSSPLSKELRTKYNVRSIPVRKDDEVQIVRGHFKSSTVYKVVSCFRKKFVLHIEHVTTEKANGQTVFVGIDPSKVVIHXXXXXXXXXXXXXXXAAGKT--DNAGKYTEEKME 478
            MK NK +TSSRRKNR+RHFNAPSH+RRK+MSSPLSKELR KY+VRS+P+RKDDEVQ+VRGH+K   V KVV  +RKK+++ IE +  EKANG +V VGI PSKVVI KLKLDKDRKKIL++K   +    + GKY EE +E
Sbjct:    1 MKLNKLVTSSRRKNRKRHFNAPSHVRRKIMSSPLSKELRQKYSVRSMPIRKDDEVQVVRGHYKGQQVGKVVQVYRKKYIIFIERIQREKANGASVHVGIHPSKVVITKLKLDKDRKKILEKKGKSRQQGQDKGKYKEETIE 141          
BLAST of 60S ribosomal protein L26 vs. Ensembl Yeast
Match: RPL26A (Ribosomal 60S subunit protein L26A; binds to 5.8S rRNA; non-essential even when paralog is also deleted; deletion has minimal affections on ribosome biosynthesis; homologous to mammalian ribosomal protein L26 and bacterial L24; RPL26A has a paralog, RPL26B, that arose from the whole genome duplication [Source:SGD;Acc:S000004336])

HSP 1 Score: 102.449 bits (254), Expect = 3.367e-29
Identity = 48/101 (47.52%), Postives = 72/101 (71.29%), Query Frame = 2
Query:   77 EITSSRRKNRQRHFNAPSHIRRKLMSSPLSKELRTKYNVRSIPVRKDDEVQIVRGHFKSSTVYKVVSCFRKKFVLHIEHVTTEKANGQTVFVGIDPSKVVI 379
            +++S RRK R+ +F APS  RR L+S+PLSKELR +Y ++++P+R+DDEV +VRG  K     K+ S +R KF + ++ VT EK NG +V + + PSK+VI
Sbjct:    7 DVSSDRRKARKAYFTAPSSQRRVLLSAPLSKELRAQYGIKALPIRRDDEVLVVRGSKKGQE-GKISSVYRLKFAVQVDKVTKEKVNGASVPINLHPSKLVI 106          
BLAST of 60S ribosomal protein L26 vs. Ensembl Yeast
Match: RPL26B (Ribosomal 60S subunit protein L26B; binds to 5.8S rRNA; non-essential even when paralog is also deleted; deletion has minimal affections on ribosome biosynthesis; homologous to mammalian ribosomal protein L26 and bacterial L24; RPL26B has a paralog, RPL26A, that arose from the whole genome duplication [Source:SGD;Acc:S000003266])

HSP 1 Score: 102.449 bits (254), Expect = 3.794e-29
Identity = 48/101 (47.52%), Postives = 72/101 (71.29%), Query Frame = 2
Query:   77 EITSSRRKNRQRHFNAPSHIRRKLMSSPLSKELRTKYNVRSIPVRKDDEVQIVRGHFKSSTVYKVVSCFRKKFVLHIEHVTTEKANGQTVFVGIDPSKVVI 379
            +++S RRK R+ +F APS  RR L+S+PLSKELR +Y ++++P+R+DDEV +VRG  K     K+ S +R KF + ++ VT EK NG +V + + PSK+VI
Sbjct:    7 DVSSDRRKARKAYFTAPSSERRVLLSAPLSKELRAQYGIKALPIRRDDEVLVVRGSKKGQE-GKISSVYRLKFAVQVDKVTKEKVNGASVPINLHPSKLVI 106          
BLAST of 60S ribosomal protein L26 vs. Ensembl Nematostella
Match: EDO49107 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RGT2])

HSP 1 Score: 158.688 bits (400), Expect = 1.529e-50
Identity = 94/140 (67.14%), Postives = 113/140 (80.71%), Query Frame = 2
Query:   62 MKFNKEITSSRRKNRQRHFNAPSHIRRKLMSSPLSKELRTKYNVRSIPVRKDDEVQIVRGHFKSSTVYKVVSCFRKKFVLHIEHVTTEKANGQTVFVGIDPSKVVIHXXXXXXXXXXXXXXXAAGKTDNAGKYTEEKMET 481
            MK N E++SSRRK+R+ HF+APS +RRKLMS+PLSKELR KYNVRSIPVRKDDEVQ+ RGHFKS  V KV+  +RKK+V+HI+ +  EKANG TV VGI PSKV I KLK+DKDRKKILDRK   K    GK+TEE+++ 
Sbjct:    1 MKRNSEVSSSRRKSRKAHFSAPSSVRRKLMSAPLSKELRQKYNVRSIPVRKDDEVQVTRGHFKSQQVGKVIQVYRKKWVIHIDRIQREKANGATVSVGIHPSKVEIVKLKIDKDRKKILDRKNRSKLAEKGKHTEEEVQA 140          
BLAST of 60S ribosomal protein L26 vs. Ensembl Medaka
Match: rpl26 (60S ribosomal protein L26 [Source:NCBI gene;Acc:101161566])

HSP 1 Score: 169.474 bits (428), Expect = 2.625e-54
Identity = 99/141 (70.21%), Postives = 115/141 (81.56%), Query Frame = 2
Query:   62 MKFNKEITSSRRKNRQRHFNAPSHIRRKLMSSPLSKELRTKYNVRSIPVRKDDEVQIVRGHFKSSTVYKVVSCFRKKFVLHIEHVTTEKANGQTVFVGIDPSKVVIHXXXXXXXXXXXXXXXAAGKTDN--AGKYTEEKME 478
            MK N  +TSSRRKNR+RHFNAPSHIRRK+MSSPLSKELR KYNVRS+P+RKDDEVQ+VRGH+K   + KVV  +RKK+V++IE V  EKANG TV VGI PSKVVI +LKLDKDRKKIL+RKA  + D    GKY EE +E
Sbjct:   10 MKLNPFVTSSRRKNRKRHFNAPSHIRRKIMSSPLSKELRQKYNVRSMPIRKDDEVQVVRGHYKGQQIGKVVQVYRKKYVIYIERVQREKANGTTVHVGIHPSKVVITRLKLDKDRKKILERKAKSRADGKEKGKYKEETIE 150          
BLAST of 60S ribosomal protein L26 vs. Ensembl Medaka
Match: rpl26 (60S ribosomal protein L26 [Source:NCBI gene;Acc:101161566])

HSP 1 Score: 169.474 bits (428), Expect = 2.712e-54
Identity = 99/141 (70.21%), Postives = 115/141 (81.56%), Query Frame = 2
Query:   62 MKFNKEITSSRRKNRQRHFNAPSHIRRKLMSSPLSKELRTKYNVRSIPVRKDDEVQIVRGHFKSSTVYKVVSCFRKKFVLHIEHVTTEKANGQTVFVGIDPSKVVIHXXXXXXXXXXXXXXXAAGKTDN--AGKYTEEKME 478
            MK N  +TSSRRKNR+RHFNAPSHIRRK+MSSPLSKELR KYNVRS+P+RKDDEVQ+VRGH+K   + KVV  +RKK+V++IE V  EKANG TV VGI PSKVVI +LKLDKDRKKIL+RKA  + D    GKY EE +E
Sbjct:    1 MKLNPFVTSSRRKNRKRHFNAPSHIRRKIMSSPLSKELRQKYNVRSMPIRKDDEVQVVRGHYKGQQIGKVVQVYRKKYVIYIERVQREKANGTTVHVGIHPSKVVITRLKLDKDRKKILERKAKSRADGKEKGKYKEETIE 141          
BLAST of 60S ribosomal protein L26 vs. Ensembl Medaka
Match: rpl26 (60S ribosomal protein L26 [Source:NCBI gene;Acc:101161566])

HSP 1 Score: 167.933 bits (424), Expect = 1.960e-53
Identity = 99/141 (70.21%), Postives = 115/141 (81.56%), Query Frame = 2
Query:   62 MKFNKEITSSRRKNRQRHFNAPSHIRRKLMSSPLSKELRTKYNVRSIPVRKDDEVQIVRGHFKSSTVYKVVSCFRKKFVLHIEHVTTEKANGQTVFVGIDPSKVVIHXXXXXXXXXXXXXXXAAGKTDN--AGKYTEEKME 478
            MK N  +TSSRRKNR+RHFNAPSHIRRK+MSSPLSKELR KYNVRS+P+RKDDEVQ+VRGH+K   + KVV  +RKK+V++IE V  EKANG TV VGI PSKVVI +LKLDKDRKKIL+RKA  + D    GKY EE +E
Sbjct:   25 MKLNPFVTSSRRKNRKRHFNAPSHIRRKIMSSPLSKELRQKYNVRSMPIRKDDEVQVVRGHYKGQQIGKVVQVYRKKYVIYIERVQREKANGTTVHVGIHPSKVVITRLKLDKDRKKILERKAKSRADGKEKGKYKEETIE 165          
BLAST of 60S ribosomal protein L26 vs. Planmine SMEST
Match: SMESG000066644.1 (SMESG000066644.1)

HSP 1 Score: 253.447 bits (646), Expect = 9.964e-88
Identity = 141/141 (100.00%), Postives = 141/141 (100.00%), Query Frame = 2
Query:   62 MKFNKEITSSRRKNRQRHFNAPSHIRRKLMSSPLSKELRTKYNVRSIPVRKDDEVQIVRGHFKSSTVYKVVSCFRKKFVLHIEHVTTEKANGQTVFVGIDPSKVVIHXXXXXXXXXXXXXXXAAGKTDNAGKYTEEKMETA 484
            MKFNKEITSSRRKNRQRHFNAPSHIRRKLMSSPLSKELRTKYNVRSIPVRKDDEVQIVRGHFKSSTVYKVVSCFRKKFVLHIEHVTTEKANGQTVFVGIDPSKVVIHKLKLDKDRKKILDRKAAGKTDNAGKYTEEKMETA
Sbjct:    1 MKFNKEITSSRRKNRQRHFNAPSHIRRKLMSSPLSKELRTKYNVRSIPVRKDDEVQIVRGHFKSSTVYKVVSCFRKKFVLHIEHVTTEKANGQTVFVGIDPSKVVIHKLKLDKDRKKILDRKAAGKTDNAGKYTEEKMETA 141          
The following BLAST results are available for this feature:
BLAST of 60S ribosomal protein L26 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5
Match NameE-valueIdentityDescription
RPL269.922e-5268.79ribosomal protein L26 [Source:HGNC Symbol;Acc:HGNC... [more]
RPL269.922e-5268.79ribosomal protein L26 [Source:HGNC Symbol;Acc:HGNC... [more]
RPL269.922e-5268.79ribosomal protein L26 [Source:HGNC Symbol;Acc:HGNC... [more]
RPL269.922e-5268.79ribosomal protein L26 [Source:HGNC Symbol;Acc:HGNC... [more]
RPL26L12.595e-5168.09ribosomal protein L26 like 1 [Source:HGNC Symbol;A... [more]
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BLAST of 60S ribosomal protein L26 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 3
Match NameE-valueIdentityDescription
rpl-261.741e-3955.7160S ribosomal protein L26 [Source:UniProtKB/Swiss... [more]
rpl-265.234e-3857.6960S ribosomal protein L26 [Source:UniProtKB/Swiss... [more]
rpl-265.824e-3857.6960S ribosomal protein L26 [Source:UniProtKB/Swiss... [more]
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BLAST of 60S ribosomal protein L26 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 3
Match NameE-valueIdentityDescription
RpL267.173e-5163.09gene:FBgn0036825 transcript:FBtr0333709[more]
RpL267.173e-5163.09gene:FBgn0036825 transcript:FBtr0347494[more]
RpL267.173e-5163.09gene:FBgn0036825 transcript:FBtr0075066[more]
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BLAST of 60S ribosomal protein L26 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 2
Match NameE-valueIdentityDescription
rpl262.763e-5470.21ribosomal protein L26 [Source:ZFIN;Acc:ZDB-GENE-04... [more]
atp6v0e12.763e-5470.21ATPase H+ transporting V0 subunit e1 [Source:ZFIN;... [more]
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BLAST of 60S ribosomal protein L26 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 1
Match NameE-valueIdentityDescription
rpl267.105e-5066.67ribosomal protein L26 [Source:NCBI gene;Acc:448683... [more]
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BLAST of 60S ribosomal protein L26 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 4
Match NameE-valueIdentityDescription
Rpl266.812e-5268.79ribosomal protein L26 [Source:MGI Symbol;Acc:MGI:1... [more]
Rpl266.812e-5268.79ribosomal protein L26 [Source:MGI Symbol;Acc:MGI:1... [more]
Rpl264.703e-4971.84ribosomal protein L26 [Source:MGI Symbol;Acc:MGI:1... [more]
Rpl261.353e-4868.09ribosomal protein L26 [Source:MGI Symbol;Acc:MGI:1... [more]
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BLAST of 60S ribosomal protein L26 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|Q95WA0|RL26_LITLI1.482e-5468.7560S ribosomal protein L26 OS=Littorina littorea OX... [more]
sp|P12749|RL26_RAT3.323e-5168.7960S ribosomal protein L26 OS=Rattus norvegicus OX=... [more]
sp|P61255|RL26_MOUSE4.765e-5168.7960S ribosomal protein L26 OS=Mus musculus OX=10090... [more]
sp|P61256|RL26_MACFA4.765e-5168.7960S ribosomal protein L26 OS=Macaca fascicularis O... [more]
sp|P61254|RL26_HUMAN4.765e-5168.7960S ribosomal protein L26 OS=Homo sapiens OX=9606 ... [more]
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BLAST of 60S ribosomal protein L26 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
A8UFE04.104e-5369.72Ribosomal protein rpl26 OS=Arenicola marina OX=634... [more]
A0A1Y1N2W91.863e-5267.59KOW domain-containing protein OS=Photinus pyralis ... [more]
A0A267EK555.389e-5268.84KOW domain-containing protein (Fragment) OS=Macros... [more]
A0A481SWK95.818e-5267.3560S ribosomal protein L26 OS=Nicoletia phytophila ... [more]
B0Z9M75.908e-5272.03Ribosomal protein rpl26 OS=Lineus viridis OX=56195... [more]
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BLAST of 60S ribosomal protein L26 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 1
Match NameE-valueIdentityDescription
rpl267.708e-5469.5060S ribosomal protein L26 [Source:NCBI gene;Acc:10... [more]
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BLAST of 60S ribosomal protein L26 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 1
Match NameE-valueIdentityDescription
rpl263.166e-5266.67ribosomal protein L26 [Source:ZFIN;Acc:ZDB-GENE-04... [more]
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BLAST of 60S ribosomal protein L26 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 2
Match NameE-valueIdentityDescription
RPL26A3.367e-2947.52Ribosomal 60S subunit protein L26A; binds to 5.8S ... [more]
RPL26B3.794e-2947.52Ribosomal 60S subunit protein L26B; binds to 5.8S ... [more]
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BLAST of 60S ribosomal protein L26 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 1
Match NameE-valueIdentityDescription
EDO491071.529e-5067.14Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
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BLAST of 60S ribosomal protein L26 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 3
Match NameE-valueIdentityDescription
rpl262.625e-5470.2160S ribosomal protein L26 [Source:NCBI gene;Acc:10... [more]
rpl262.712e-5470.2160S ribosomal protein L26 [Source:NCBI gene;Acc:10... [more]
rpl261.960e-5370.2160S ribosomal protein L26 [Source:NCBI gene;Acc:10... [more]
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BLAST of 60S ribosomal protein L26 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 1
Match NameE-valueIdentityDescription
SMESG000066644.19.964e-88100.00SMESG000066644.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30013613 ID=SMED30013613|Name=60S ribosomal protein L26|organism=Schmidtea mediterranea sexual|type=transcript|length=509bp
TAATAATTTAAATTTTGTTTAAATATTTTTAAGGAGATTGTAACTAAATT
TTCAAATAAAAATGAAGTTTAATAAAGAGATAACTTCCAGCAGACGTAAG
AACCGTCAAAGACATTTTAATGCTCCATCCCACATTCGTAGGAAGTTGAT
GAGTTCTCCTCTTTCAAAGGAATTGAGAACTAAATATAATGTTAGATCAA
TTCCAGTACGAAAAGATGATGAAGTTCAAATTGTCCGAGGACATTTTAAA
AGTTCAACTGTGTATAAAGTTGTCAGTTGTTTCAGAAAGAAATTTGTTCT
CCATATTGAACATGTTACCACTGAAAAAGCTAATGGTCAAACTGTTTTTG
TTGGTATCGATCCATCGAAAGTTGTCATCCACAAATTGAAATTAGACAAA
GATAGAAAGAAGATTCTTGATCGTAAAGCAGCTGGTAAAACCGACAATGC
TGGTAAATATACCGAAGAAAAGATGGAAACTGCTTAATTTAATAAAGCTT
TTTGGATAT
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protein sequence of SMED30013613-orf-1

>SMED30013613-orf-1 ID=SMED30013613-orf-1|Name=SMED30013613-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=142bp
MKFNKEITSSRRKNRQRHFNAPSHIRRKLMSSPLSKELRTKYNVRSIPVR
KDDEVQIVRGHFKSSTVYKVVSCFRKKFVLHIEHVTTEKANGQTVFVGID
PSKVVIHKLKLDKDRKKILDRKAAGKTDNAGKYTEEKMETA*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000026gut
PLANA:0000429neoblast
PLANA:0002109X1 cell
Vocabulary: INTERPRO
TermDefinition
IPR041988KOW_RPL26/RPL24
IPR005756Ribosomal_L26/L24P_euk/arc
IPR014722Rib_L2_dom2
IPR008991Translation_prot_SH3-like_sf
Vocabulary: biological process
TermDefinition
GO:0006412translation
Vocabulary: cellular component
TermDefinition
GO:0015934large ribosomal subunit
GO:0005622intracellular
GO:0005840ribosome
GO:0030529intracellular ribonucleoprotein complex
Vocabulary: molecular function
TermDefinition
GO:0003735structural constituent of ribosome
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR014722Ribosomal protein L2, domain 2GENE3DG3DSA:2.30.30.30coord: 1..141
e-value: 4.7E-54
score: 184.2
IPR005756Ribosomal protein L26/L24, eukaryotic/archaealPFAMPF16906Ribosomal_L26coord: 8..122
e-value: 1.1E-39
score: 134.8
IPR005756Ribosomal protein L26/L24, eukaryotic/archaealTIGRFAMTIGR01080TIGR01080coord: 9..123
e-value: 2.0E-43
score: 145.4
IPR005756Ribosomal protein L26/L24, eukaryotic/archaealPANTHERPTHR1114360S RIBOSOMAL PROTEIN L26 FAMILY MEMBERcoord: 1..139
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 120..141
NoneNo IPR availablePANTHERPTHR11143:SF1060S RIBOSOMAL PROTEIN L26-LIKE 1coord: 1..139
IPR041988Ribosomal Protein L26/L24, KOW domainCDDcd06089KOW_RPL26coord: 52..106
e-value: 3.31087E-8
score: 45.5834
IPR008991Translation protein SH3-like domain superfamilySUPERFAMILYSSF50104Translation proteins SH3-like domaincoord: 8..126