Ring box protein

Overview
NameRing box protein
Smed IDSMED30013600
Length (bp)459
Neoblast Clusters

Zeng et. al., 2018



▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)



Explore this single cell expression dataset with our NB Cluster Shiny App



 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of Ring box protein (SMED30013600) t-SNE clustered cells

Violin plots show distribution of expression levels for Ring box protein (SMED30013600) in cells (dots) of each of the 12 neoblast clusters.

 

back to top

 

Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of Ring box protein (SMED30013600) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for Ring box protein (SMED30013600) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

back to top

 

Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
Sort Descending | Sort Ascending | Only Non-Zero Values | Tile/Chart | Reset

Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

back to top
Anatomical Expression

PAGE et. al., 2020



SMED30013600

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 3

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
neoblastSMED30013600SMESG000036014.1 dd_Smed_v4_1136_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
parenchymal cellSMED30013600SMESG000036014.1 dd_Smed_v4_1136_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
head regionSMED30013600SMESG000036014.1 OX_Smed_1.0.04761ox_Smed_v2PMID:24238224
Kao et al., 2013		whole organism asexual adult RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
[Close]
BLAST of Ring box protein vs. Ensembl Human
Match: RBX1 (ring-box 1 [Source:HGNC Symbol;Acc:HGNC:9928])

HSP 1 Score: 194.512 bits (493), Expect = 9.808e-65
Identity = 92/111 (82.88%), Postives = 98/111 (88.29%), Query Frame = 3 
Query:   57 MSTAMEVDELNAAGASGNNPTKKRFEIKKWNAVALWAWDIVVDNCAICRNHIMDLCIECQANHATATSEECTVAWGVCNHAFHFHCISRWLKTRQVCPLDNREWEFQKYGH 389
            M+ AM+VD       + +   KKRFE+KKWNAVALWAWDIVVDNCAICRNHIMDLCIECQAN A+ATSEECTVAWGVCNHAFHFHCISRWLKTRQVCPLDNREWEFQKYGH
Sbjct:    1 MAAAMDVD---TPSGTNSGAGKKRFEVKKWNAVALWAWDIVVDNCAICRNHIMDLCIECQANQASATSEECTVAWGVCNHAFHFHCISRWLKTRQVCPLDNREWEFQKYGH 108
[Close]
BLAST of Ring box protein vs. Ensembl Human
Match: RNF7 (ring finger protein 7 [Source:HGNC Symbol;Acc:HGNC:10070])

HSP 1 Score: 97.4413 bits (241), Expect = 2.142e-26
Identity = 44/88 (50.00%), Postives = 58/88 (65.91%), Query Frame = 3 
Query:  123 KRFEIKKWNAVALWAWDIVVDNCAICRNHIMDLCIECQANHATATSEECTVAWGVCNHAFHFHCISRWLKTRQVCPLDNREWEFQKYG 386
            K F +KKWNAVA+W+WD+  D CAICR  +MD C+ CQA +     E+C V WG CNH+FH  C+S W+K    CPL  ++W  Q+ G
Sbjct:   28 KMFSLKKWNAVAMWSWDVECDTCAICRVQVMDACLRCQAEN---KQEDCVVVWGECNHSFHNCCMSLWVKQNNRCPLCQQDWVVQRIG 112
[Close]
BLAST of Ring box protein vs. Ensembl Human
Match: RNF7 (ring finger protein 7 [Source:HGNC Symbol;Acc:HGNC:10070])

HSP 1 Score: 75.0998 bits (183), Expect = 7.954e-18
Identity = 37/88 (42.05%), Postives = 48/88 (54.55%), Query Frame = 3 
Query:  123 KRFEIKKWNAVALWAWDIVVDNCAICRNHIMDLCIECQANHATATSEECTVAWGVCNHAFHFHCISRWLKTRQVCPLDNREWEFQKYG 386
            K F +KKWNAVA+W+WD+  D CAICR  +M                   V WG CNH+FH  C+S W+K    CPL  ++W  Q+ G
Sbjct:   28 KMFSLKKWNAVAMWSWDVECDTCAICRVQVM-------------------VVWGECNHSFHNCCMSLWVKQNNRCPLCQQDWVVQRIG 96
[Close]
BLAST of Ring box protein vs. Ensembl Human
Match: ANAPC11 (anaphase promoting complex subunit 11 [Source:HGNC Symbol;Acc:HGNC:14452])

HSP 1 Score: 69.707 bits (169), Expect = 5.429e-16
Identity = 34/88 (38.64%), Postives = 50/88 (56.82%), Query Frame = 3 
Query:  126 RFEIKKWNAVALWAWDIVVDNCAICRNHIMDLCIECQANHATATSEECTVAWGVCNHAFHFHCISRWLKTRQV---CPLDNREWEFQK 380
            + +IK WN VA W W    +NC ICR      C +C+        ++C + WG C+H FH HCI +WL  +QV   CP+  +EW+F++
Sbjct:    2 KVKIKCWNGVATWLWVANDENCGICRMAFNGCCPDCKV-----PGDDCPLVWGQCSHCFHMHCILKWLHAQQVQQHCPMCRQEWKFKE 84
[Close]
BLAST of Ring box protein vs. Ensembl Human
Match: ANAPC11 (anaphase promoting complex subunit 11 [Source:HGNC Symbol;Acc:HGNC:14452])

HSP 1 Score: 69.707 bits (169), Expect = 5.429e-16
Identity = 34/88 (38.64%), Postives = 50/88 (56.82%), Query Frame = 3 
Query:  126 RFEIKKWNAVALWAWDIVVDNCAICRNHIMDLCIECQANHATATSEECTVAWGVCNHAFHFHCISRWLKTRQV---CPLDNREWEFQK 380
            + +IK WN VA W W    +NC ICR      C +C+        ++C + WG C+H FH HCI +WL  +QV   CP+  +EW+F++
Sbjct:    2 KVKIKCWNGVATWLWVANDENCGICRMAFNGCCPDCKV-----PGDDCPLVWGQCSHCFHMHCILKWLHAQQVQQHCPMCRQEWKFKE 84
[Close]
BLAST of Ring box protein vs. Ensembl Celegans
Match: rbx-1 (RING-box protein 1 [Source:UniProtKB/Swiss-Prot;Acc:Q23457])

HSP 1 Score: 184.111 bits (466), Expect = 4.436e-61
Identity = 88/110 (80.00%), Postives = 93/110 (84.55%), Query Frame = 3 
Query:   60 STAMEVDELNAAGASGNNPTKKRFEIKKWNAVALWAWDIVVDNCAICRNHIMDLCIECQANHATATSEECTVAWGVCNHAFHFHCISRWLKTRQVCPLDNREWEFQKYGH 389
            STAMEV+E      + N   KKRFE+KKW+AVALWAWDI VDNCAICRNHIMDLCIECQAN A    +ECTVAWG CNHAFHFHCISRWLKTRQVCPLDNREWEFQKYGH
Sbjct:    7 STAMEVEE------ATNQTVKKRFEVKKWSAVALWAWDIQVDNCAICRNHIMDLCIECQANQAAGLKDECTVAWGNCNHAFHFHCISRWLKTRQVCPLDNREWEFQKYGH 110
[Close]
BLAST of Ring box protein vs. Ensembl Celegans
Match: rbx-1 (RING-box protein 1 [Source:UniProtKB/Swiss-Prot;Acc:Q23457])

HSP 1 Score: 184.111 bits (466), Expect = 4.436e-61
Identity = 88/110 (80.00%), Postives = 93/110 (84.55%), Query Frame = 3 
Query:   60 STAMEVDELNAAGASGNNPTKKRFEIKKWNAVALWAWDIVVDNCAICRNHIMDLCIECQANHATATSEECTVAWGVCNHAFHFHCISRWLKTRQVCPLDNREWEFQKYGH 389
            STAMEV+E      + N   KKRFE+KKW+AVALWAWDI VDNCAICRNHIMDLCIECQAN A    +ECTVAWG CNHAFHFHCISRWLKTRQVCPLDNREWEFQKYGH
Sbjct:    7 STAMEVEE------ATNQTVKKRFEVKKWSAVALWAWDIQVDNCAICRNHIMDLCIECQANQAAGLKDECTVAWGNCNHAFHFHCISRWLKTRQVCPLDNREWEFQKYGH 110
[Close]
BLAST of Ring box protein vs. Ensembl Celegans
Match: rbx-2 (Yeast RBX (Ring finger protein) homolog [Source:UniProtKB/TrEMBL;Acc:P91404])

HSP 1 Score: 92.0485 bits (227), Expect = 1.063e-24
Identity = 42/87 (48.28%), Postives = 60/87 (68.97%), Query Frame = 3 
Query:  111 NPTKKR-FEIKKWNAVALWAWDIVVDNCAICRNHIMDLCIECQANHATATSEECTVAWGVCNHAFHFHCISRWLKTRQVCPLDNREW 368
            NP++ R F +KKWNA+A+WAWD+  D CAICR H+M+ C+ CQ+      S EC V WG CNH+FH  C+++W++    CPL  ++W
Sbjct:   23 NPSESRPFVLKKWNALAVWAWDVECDTCAICRVHLMEECLRCQSE----PSAECYVVWGDCNHSFHHCCMTQWIRQNNRCPLCQKDW 105
[Close]
BLAST of Ring box protein vs. Ensembl Celegans
Match: apc-11 (Anaphase-promoting complex subunit 11 [Source:UniProtKB/Swiss-Prot;Acc:Q20052])

HSP 1 Score: 50.447 bits (119), Expect = 1.983e-8
Identity = 28/90 (31.11%), Postives = 41/90 (45.56%), Query Frame = 3 
Query:  117 TKKRFEIKKWNAVALWAW-DIVVDNCAICRNHIMDLCIECQANHATATSEECTVAWGVCNHAFHFHCISRWL-----KTRQVCPLDNREW 368
            T+    +KK +    W W     D C ICR      C  C+        ++C +  G+C HAFH HCI +W+     + R  CPL  ++W
Sbjct:   47 TRMSITVKKLHVCGEWKWLQGGEDTCGICRMEFESACNMCKF-----PGDDCPLVLGICRHAFHRHCIDKWIAAPTNQPRAQCPLCRQDW 131
[Close]
BLAST of Ring box protein vs. Ensembl Celegans
Match: apc-11 (Anaphase-promoting complex subunit 11 [Source:UniProtKB/Swiss-Prot;Acc:Q20052])

HSP 1 Score: 50.447 bits (119), Expect = 1.983e-8
Identity = 28/90 (31.11%), Postives = 41/90 (45.56%), Query Frame = 3 
Query:  117 TKKRFEIKKWNAVALWAW-DIVVDNCAICRNHIMDLCIECQANHATATSEECTVAWGVCNHAFHFHCISRWL-----KTRQVCPLDNREW 368
            T+    +KK +    W W     D C ICR      C  C+        ++C +  G+C HAFH HCI +W+     + R  CPL  ++W
Sbjct:   47 TRMSITVKKLHVCGEWKWLQGGEDTCGICRMEFESACNMCKF-----PGDDCPLVLGICRHAFHRHCIDKWIAAPTNQPRAQCPLCRQDW 131
[Close]
BLAST of Ring box protein vs. Ensembl Fly
Match: Roc1a (gene:FBgn0025638 transcript:FBtr0343564)

HSP 1 Score: 191.43 bits (485), Expect = 6.525e-64
Identity = 92/108 (85.19%), Postives = 97/108 (89.81%), Query Frame = 3 
Query:   69 MEVDELN-AAGASGNNPTKKRFEIKKWNAVALWAWDIVVDNCAICRNHIMDLCIECQANHATATSEECTVAWGVCNHAFHFHCISRWLKTRQVCPLDNREWEFQKYGH 389
            MEVDE      +S +   KKRFE+KKWNAVALWAWDIVVDNCAICRNHIMDLCIECQAN A+ATSEECTVAWGVCNHAFHFHCISRWLKTRQVCPLDNREW+FQKYGH
Sbjct:    1 MEVDEDGYEVPSSSSKGDKKRFEVKKWNAVALWAWDIVVDNCAICRNHIMDLCIECQANQASATSEECTVAWGVCNHAFHFHCISRWLKTRQVCPLDNREWDFQKYGH 108
[Close]
BLAST of Ring box protein vs. Ensembl Fly
Match: Roc1a (gene:FBgn0025638 transcript:FBtr0070122)

HSP 1 Score: 191.43 bits (485), Expect = 6.525e-64
Identity = 92/108 (85.19%), Postives = 97/108 (89.81%), Query Frame = 3 
Query:   69 MEVDELN-AAGASGNNPTKKRFEIKKWNAVALWAWDIVVDNCAICRNHIMDLCIECQANHATATSEECTVAWGVCNHAFHFHCISRWLKTRQVCPLDNREWEFQKYGH 389
            MEVDE      +S +   KKRFE+KKWNAVALWAWDIVVDNCAICRNHIMDLCIECQAN A+ATSEECTVAWGVCNHAFHFHCISRWLKTRQVCPLDNREW+FQKYGH
Sbjct:    1 MEVDEDGYEVPSSSSKGDKKRFEVKKWNAVALWAWDIVVDNCAICRNHIMDLCIECQANQASATSEECTVAWGVCNHAFHFHCISRWLKTRQVCPLDNREWDFQKYGH 108
[Close]
BLAST of Ring box protein vs. Ensembl Fly
Match: Roc1a (gene:FBgn0025638 transcript:FBtr0308651)

HSP 1 Score: 177.948 bits (450), Expect = 3.557e-58
Identity = 92/136 (67.65%), Postives = 97/136 (71.32%), Query Frame = 3 
Query:   69 MEVDELN-AAGASGNNPTKKRFEIKK----------------------------WNAVALWAWDIVVDNCAICRNHIMDLCIECQANHATATSEECTVAWGVCNHAFHFHCISRWLKTRQVCPLDNREWEFQKYGH 389
            MEVDE      +S +   KKRFE+KK                            WNAVALWAWDIVVDNCAICRNHIMDLCIECQAN A+ATSEECTVAWGVCNHAFHFHCISRWLKTRQVCPLDNREW+FQKYGH
Sbjct:    1 MEVDEDGYEVPSSSSKGDKKRFEVKKVSGQQKSRVIVNECTDGNTSSFPLRRKQWNAVALWAWDIVVDNCAICRNHIMDLCIECQANQASATSEECTVAWGVCNHAFHFHCISRWLKTRQVCPLDNREWDFQKYGH 136
[Close]
BLAST of Ring box protein vs. Ensembl Fly
Match: Roc1b (gene:FBgn0040291 transcript:FBtr0072547)

HSP 1 Score: 142.895 bits (359), Expect = 1.675e-44
Identity = 66/103 (64.08%), Postives = 78/103 (75.73%), Query Frame = 3 
Query:   78 DELNAAGASGNNPTKKRFEIKKWNAVALWAWDIVVDNCAICRNHIMDLCIECQANHATATSEECTVAWGVCNHAFHFHCISRWLKTRQVCPLDNREWEFQKYG 386
            DE  +          +RF +KKW A A+W WD+ VDNCAICRNHIM+LCIECQA+   A  +ECTVAWG CNHAFH+HCI+RWLKTR VCPLDN+EW +QKYG
Sbjct:   20 DEEPSCSGGAVQARTERFVVKKWVAHAMWGWDVAVDNCAICRNHIMNLCIECQAD-PNANQDECTVAWGECNHAFHYHCIARWLKTRLVCPLDNKEWVYQKYG 121
[Close]
BLAST of Ring box protein vs. Ensembl Fly
Match: Roc2 (gene:FBgn0044020 transcript:FBtr0302211)

HSP 1 Score: 100.138 bits (248), Expect = 9.099e-28
Identity = 48/106 (45.28%), Postives = 65/106 (61.32%), Query Frame = 3 
Query:   75 VDELNAAGASGNNPTKKRFEIKKWNAVALWAWDIVVDNCAICRNHIMDLCIECQANHA--TATSEECTVAWGVCNHAFHFHCISRWLKTRQVCPLDNREWEFQKYG 386
            VD     G +G    +K F +KKWNAVA+W+WD+  D CAICR  +MD C+ CQA++       ++C V WG CNH+FH  C+S W+K    CPL  +EW  Q+ G
Sbjct:    9 VDRPTDDGDAGK--PEKMFTLKKWNAVAMWSWDVECDICAICRVQVMDSCLRCQADNKRDVMGRQDCVVVWGECNHSFHHCCMSLWVKQNNRCPLCQQEWSIQRMG 112
[Close]
BLAST of Ring box protein vs. Ensembl Zebrafish
Match: rbx1 (ring-box 1, E3 ubiquitin protein ligase [Source:ZFIN;Acc:ZDB-GENE-041008-106])

HSP 1 Score: 196.438 bits (498), Expect = 9.784e-66
Identity = 93/111 (83.78%), Postives = 100/111 (90.09%), Query Frame = 3 
Query:   57 MSTAMEVDELNAAGASGNNPTKKRFEIKKWNAVALWAWDIVVDNCAICRNHIMDLCIECQANHATATSEECTVAWGVCNHAFHFHCISRWLKTRQVCPLDNREWEFQKYGH 389
            M+ AM+VD  + A +     +KKRFE+KKWNAVALWAWDIVVDNCAICRNHIMDLCIECQAN A+ATSEECTVAWGVCNHAFHFHCISRWLKTRQVCPLDNREWEFQKYGH
Sbjct:    1 MAAAMDVDTPSGANSGA---SKKRFEVKKWNAVALWAWDIVVDNCAICRNHIMDLCIECQANQASATSEECTVAWGVCNHAFHFHCISRWLKTRQVCPLDNREWEFQKYGH 108
[Close]
BLAST of Ring box protein vs. Ensembl Zebrafish
Match: rbx1 (ring-box 1, E3 ubiquitin protein ligase [Source:ZFIN;Acc:ZDB-GENE-041008-106])

HSP 1 Score: 124.405 bits (311), Expect = 7.265e-38
Identity = 57/59 (96.61%), Postives = 58/59 (98.31%), Query Frame = 3 
Query:  213 MDLCIECQANHATATSEECTVAWGVCNHAFHFHCISRWLKTRQVCPLDNREWEFQKYGH 389
            MDLCIECQAN A+ATSEECTVAWGVCNHAFHFHCISRWLKTRQVCPLDNREWEFQKYGH
Sbjct:    1 MDLCIECQANQASATSEECTVAWGVCNHAFHFHCISRWLKTRQVCPLDNREWEFQKYGH 59
[Close]
BLAST of Ring box protein vs. Ensembl Zebrafish
Match: rnf7 (ring finger protein 7 [Source:ZFIN;Acc:ZDB-GENE-050220-12])

HSP 1 Score: 97.0561 bits (240), Expect = 1.750e-26
Identity = 44/88 (50.00%), Postives = 58/88 (65.91%), Query Frame = 3 
Query:  123 KRFEIKKWNAVALWAWDIVVDNCAICRNHIMDLCIECQANHATATSEECTVAWGVCNHAFHFHCISRWLKTRQVCPLDNREWEFQKYG 386
            K F +KKWNAVA+W+WD+  D CAICR  +MD C+ CQA +     E+C V WG CNH+FH  C+S W+K    CPL  ++W  Q+ G
Sbjct:   28 KMFSLKKWNAVAMWSWDVECDTCAICRVQVMDACLRCQAEN---KQEDCVVVWGECNHSFHNCCMSLWVKQNNRCPLCQQDWVVQRIG 112
[Close]
BLAST of Ring box protein vs. Ensembl Zebrafish
Match: anapc11 (APC11 anaphase promoting complex subunit 11 homolog (yeast) [Source:ZFIN;Acc:ZDB-GENE-061013-383])

HSP 1 Score: 73.1738 bits (178), Expect = 2.062e-17
Identity = 34/88 (38.64%), Postives = 52/88 (59.09%), Query Frame = 3 
Query:  126 RFEIKKWNAVALWAWDIVVDNCAICRNHIMDLCIECQANHATATSEECTVAWGVCNHAFHFHCISRWLKTRQV---CPLDNREWEFQK 380
            + +IK+WN VA W W    +NC ICR      C +C+        ++C + WG C+H FH HCI +WL ++QV   CP+  +EW+F++
Sbjct:    2 KVKIKQWNGVASWLWVANDENCGICRASFNGCCPDCKV-----PGDDCPLVWGQCSHCFHMHCILKWLNSQQVQQQCPMCRQEWKFKE 84
[Close]
BLAST of Ring box protein vs. Ensembl Zebrafish
Match: anapc11 (APC11 anaphase promoting complex subunit 11 homolog (yeast) [Source:ZFIN;Acc:ZDB-GENE-061013-383])

HSP 1 Score: 73.1738 bits (178), Expect = 2.062e-17
Identity = 34/88 (38.64%), Postives = 52/88 (59.09%), Query Frame = 3 
Query:  126 RFEIKKWNAVALWAWDIVVDNCAICRNHIMDLCIECQANHATATSEECTVAWGVCNHAFHFHCISRWLKTRQV---CPLDNREWEFQK 380
            + +IK+WN VA W W    +NC ICR      C +C+        ++C + WG C+H FH HCI +WL ++QV   CP+  +EW+F++
Sbjct:    2 KVKIKQWNGVASWLWVANDENCGICRASFNGCCPDCKV-----PGDDCPLVWGQCSHCFHMHCILKWLNSQQVQQQCPMCRQEWKFKE 84
[Close]
BLAST of Ring box protein vs. Ensembl Xenopus
Match: RBX1 (ring-box 1, E3 ubiquitin protein ligase [Source:NCBI gene;Acc:100379935])

HSP 1 Score: 199.134 bits (505), Expect = 1.542e-66
Identity = 94/113 (83.19%), Postives = 101/113 (89.38%), Query Frame = 3 
Query:   51 F*MSTAMEVDELNAAGASGNNPTKKRFEIKKWNAVALWAWDIVVDNCAICRNHIMDLCIECQANHATATSEECTVAWGVCNHAFHFHCISRWLKTRQVCPLDNREWEFQKYGH 389
            F M+ AM+VD       + N+ +KKRFE+KKWNAVALWAWDIVVDNCAICRNHIMDLCIECQAN A+ATSEECTVAWGVCNHAFHFHCISRWLKTRQVCPLDNREWEFQKYGH
Sbjct:   11 FKMAAAMDVD---TPSGTNNSASKKRFEVKKWNAVALWAWDIVVDNCAICRNHIMDLCIECQANQASATSEECTVAWGVCNHAFHFHCISRWLKTRQVCPLDNREWEFQKYGH 120
[Close]
BLAST of Ring box protein vs. Ensembl Xenopus
Match: RBX1 (ring-box 1, E3 ubiquitin protein ligase [Source:NCBI gene;Acc:100379935])

HSP 1 Score: 194.512 bits (493), Expect = 1.407e-64
Identity = 91/109 (83.49%), Postives = 98/109 (89.91%), Query Frame = 3 
Query:   57 MSTAMEVDELNAAGASGNNPTKKRFEIKKWNAVALWAWDIVVDNCAICRNHIMDLCIECQANHATATSEECTVAWGVCNHAFHFHCISRWLKTRQVCPLDNREWEFQKY 383
            M+ AM+VD       + N+ +KKRFE+KKWNAVALWAWDIVVDNCAICRNHIMDLCIECQAN A+ATSEECTVAWGVCNHAFHFHCISRWLKTRQVCPLDNREWEFQKY
Sbjct:    1 MAAAMDVD---TPSGTNNSASKKRFEVKKWNAVALWAWDIVVDNCAICRNHIMDLCIECQANQASATSEECTVAWGVCNHAFHFHCISRWLKTRQVCPLDNREWEFQKY 106
[Close]
BLAST of Ring box protein vs. Ensembl Xenopus
Match: rnf7 (ring finger protein 7 [Source:NCBI gene;Acc:100135737])

HSP 1 Score: 98.9821 bits (245), Expect = 2.647e-27
Identity = 48/97 (49.48%), Postives = 62/97 (63.92%), Query Frame = 3 
Query:   96 GASGNNPTKKRFEIKKWNAVALWAWDIVVDNCAICRNHIMDLCIECQANHATATSEECTVAWGVCNHAFHFHCISRWLKTRQVCPLDNREWEFQKYG 386
            GASG     K F +KKWNAVA+W+WD+  D CAICR  +MD C+ CQA +     E+C V WG CNH+FH  C+S W+K    CPL  ++W  Q+ G
Sbjct:    9 GASG----PKMFSLKKWNAVAMWSWDVECDTCAICRVQVMDACLRCQAEN---KQEDCVVVWGECNHSFHNCCMSLWVKQNNRCPLCQQDWVVQRIG 98
[Close]
BLAST of Ring box protein vs. Ensembl Xenopus
Match: gnb1l (guanine nucleotide binding protein (G protein), beta polypeptide 1-like [Source:Xenbase;Acc:XB-GENE-1010503])

HSP 1 Score: 71.2478 bits (173), Expect = 1.536e-16
Identity = 35/88 (39.77%), Postives = 50/88 (56.82%), Query Frame = 3 
Query:  126 RFEIKKWNAVALWAWDIVVDNCAICRNHIMDLCIECQANHATATSEECTVAWGVCNHAFHFHCISRWLKTRQV---CPLDNREWEFQK 380
            +  +K WN VA W W    DNC ICR      C EC+        ++C + WG C+H FH HCI +WL ++QV   CP+  +EW+F++
Sbjct:    2 KVRLKCWNGVASWQWVANDDNCGICRMAFNGCCPECKI-----PGDDCPLVWGHCSHCFHMHCILKWLNSQQVQQHCPMCRQEWKFKE 84
[Close]
BLAST of Ring box protein vs. Ensembl Mouse
Match: Rbx1 (ring-box 1 [Source:MGI Symbol;Acc:MGI:1891829])

HSP 1 Score: 194.512 bits (493), Expect = 6.734e-65
Identity = 92/111 (82.88%), Postives = 98/111 (88.29%), Query Frame = 3 
Query:   57 MSTAMEVDELNAAGASGNNPTKKRFEIKKWNAVALWAWDIVVDNCAICRNHIMDLCIECQANHATATSEECTVAWGVCNHAFHFHCISRWLKTRQVCPLDNREWEFQKYGH 389
            M+ AM+VD       + +   KKRFE+KKWNAVALWAWDIVVDNCAICRNHIMDLCIECQAN A+ATSEECTVAWGVCNHAFHFHCISRWLKTRQVCPLDNREWEFQKYGH
Sbjct:    1 MAAAMDVD---TPSGTNSGAGKKRFEVKKWNAVALWAWDIVVDNCAICRNHIMDLCIECQANQASATSEECTVAWGVCNHAFHFHCISRWLKTRQVCPLDNREWEFQKYGH 108
[Close]
BLAST of Ring box protein vs. Ensembl Mouse
Match: Rbx1 (ring-box 1 [Source:MGI Symbol;Acc:MGI:1891829])

HSP 1 Score: 124.405 bits (311), Expect = 7.841e-38
Identity = 57/59 (96.61%), Postives = 58/59 (98.31%), Query Frame = 3 
Query:  213 MDLCIECQANHATATSEECTVAWGVCNHAFHFHCISRWLKTRQVCPLDNREWEFQKYGH 389
            MDLCIECQAN A+ATSEECTVAWGVCNHAFHFHCISRWLKTRQVCPLDNREWEFQKYGH
Sbjct:    1 MDLCIECQANQASATSEECTVAWGVCNHAFHFHCISRWLKTRQVCPLDNREWEFQKYGH 59
[Close]
BLAST of Ring box protein vs. Ensembl Mouse
Match: Rbx1 (ring-box 1 [Source:MGI Symbol;Acc:MGI:1891829])

HSP 1 Score: 124.79 bits (312), Expect = 9.521e-38
Identity = 61/85 (71.76%), Postives = 68/85 (80.00%), Query Frame = 3 
Query:   57 MSTAMEVDELNAAGASGNNPTKKRFEIKKWNAVALWAWDIVVDNCAICRNHIMDLCIECQANHATATSEECTVAWGVCNHAFHFH 311
            M+ AM+VD       + +   KKRFE+KKWNAVALWAWDIVVDNCAICRNHIMDLCIECQAN A+ATSEECTVAWGVCN   H +
Sbjct:    1 MAAAMDVD---TPSGTNSGAGKKRFEVKKWNAVALWAWDIVVDNCAICRNHIMDLCIECQANQASATSEECTVAWGVCNVRNHLY 82
[Close]
BLAST of Ring box protein vs. Ensembl Mouse
Match: Rnf7 (ring finger protein 7 [Source:MGI Symbol;Acc:MGI:1337096])

HSP 1 Score: 97.0561 bits (240), Expect = 1.640e-26
Identity = 44/88 (50.00%), Postives = 58/88 (65.91%), Query Frame = 3 
Query:  123 KRFEIKKWNAVALWAWDIVVDNCAICRNHIMDLCIECQANHATATSEECTVAWGVCNHAFHFHCISRWLKTRQVCPLDNREWEFQKYG 386
            K F +KKWNAVA+W+WD+  D CAICR  +MD C+ CQA +     E+C V WG CNH+FH  C+S W+K    CPL  ++W  Q+ G
Sbjct:   28 KMFSLKKWNAVAMWSWDVECDTCAICRVQVMDACLRCQAEN---KQEDCVVVWGECNHSFHNCCMSLWVKQNNRCPLCQQDWVVQRIG 112
[Close]
BLAST of Ring box protein vs. Ensembl Mouse
Match: Gm7075 (predicted gene 7075 [Source:MGI Symbol;Acc:MGI:3646561])

HSP 1 Score: 93.9745 bits (232), Expect = 3.481e-25
Identity = 42/88 (47.73%), Postives = 57/88 (64.77%), Query Frame = 3 
Query:  123 KRFEIKKWNAVALWAWDIVVDNCAICRNHIMDLCIECQANHATATSEECTVAWGVCNHAFHFHCISRWLKTRQVCPLDNREWEFQKYG 386
            K F +KKWNAVA+W+WD+  D CA CR  +MD C+ CQA +     ++C V WG CNH+FH  C+S W+K    CPL  ++W  Q+ G
Sbjct:   27 KMFSLKKWNAVAMWSWDVECDTCATCRVQVMDACLRCQAEN---KQKDCVVVWGECNHSFHNCCMSLWVKQNNRCPLCQQDWVVQRIG 111
[Close]
BLAST of Ring box protein vs. UniProt/SwissProt
Match: sp|Q8QG64|RBX1_SALSA (RING-box protein 1 OS=Salmo salar OX=8030 GN=rbx1 PE=2 SV=2)

HSP 1 Score: 196.823 bits (499), Expect = 4.460e-65
Identity = 93/111 (83.78%), Postives = 100/111 (90.09%), Query Frame = 3 
Query:   57 MSTAMEVDELNAAGASGNNPTKKRFEIKKWNAVALWAWDIVVDNCAICRNHIMDLCIECQANHATATSEECTVAWGVCNHAFHFHCISRWLKTRQVCPLDNREWEFQKYGH 389
            M+ AM+VD      A+ +  +KKRFE+KKWNAVALWAWDIVVDNCAICRNHIMDLCIECQAN A+ATSEECTVAWGVCNHAFHFHCISRWLKTRQVCPLDNREWEFQKYGH
Sbjct:    1 MAAAMDVD---TPSATNSGASKKRFEVKKWNAVALWAWDIVVDNCAICRNHIMDLCIECQANQASATSEECTVAWGVCNHAFHFHCISRWLKTRQVCPLDNREWEFQKYGH 108
[Close]
BLAST of Ring box protein vs. UniProt/SwissProt
Match: sp|P62878|RBX1_MOUSE (E3 ubiquitin-protein ligase RBX1 OS=Mus musculus OX=10090 GN=Rbx1 PE=1 SV=1)

HSP 1 Score: 194.512 bits (493), Expect = 4.710e-64
Identity = 92/111 (82.88%), Postives = 98/111 (88.29%), Query Frame = 3 
Query:   57 MSTAMEVDELNAAGASGNNPTKKRFEIKKWNAVALWAWDIVVDNCAICRNHIMDLCIECQANHATATSEECTVAWGVCNHAFHFHCISRWLKTRQVCPLDNREWEFQKYGH 389
            M+ AM+VD       + +   KKRFE+KKWNAVALWAWDIVVDNCAICRNHIMDLCIECQAN A+ATSEECTVAWGVCNHAFHFHCISRWLKTRQVCPLDNREWEFQKYGH
Sbjct:    1 MAAAMDVD---TPSGTNSGAGKKRFEVKKWNAVALWAWDIVVDNCAICRNHIMDLCIECQANQASATSEECTVAWGVCNHAFHFHCISRWLKTRQVCPLDNREWEFQKYGH 108
[Close]
BLAST of Ring box protein vs. UniProt/SwissProt
Match: sp|P62877|RBX1_HUMAN (E3 ubiquitin-protein ligase RBX1 OS=Homo sapiens OX=9606 GN=RBX1 PE=1 SV=1)

HSP 1 Score: 194.512 bits (493), Expect = 4.710e-64
Identity = 92/111 (82.88%), Postives = 98/111 (88.29%), Query Frame = 3 
Query:   57 MSTAMEVDELNAAGASGNNPTKKRFEIKKWNAVALWAWDIVVDNCAICRNHIMDLCIECQANHATATSEECTVAWGVCNHAFHFHCISRWLKTRQVCPLDNREWEFQKYGH 389
            M+ AM+VD       + +   KKRFE+KKWNAVALWAWDIVVDNCAICRNHIMDLCIECQAN A+ATSEECTVAWGVCNHAFHFHCISRWLKTRQVCPLDNREWEFQKYGH
Sbjct:    1 MAAAMDVD---TPSGTNSGAGKKRFEVKKWNAVALWAWDIVVDNCAICRNHIMDLCIECQANQASATSEECTVAWGVCNHAFHFHCISRWLKTRQVCPLDNREWEFQKYGH 108
[Close]
BLAST of Ring box protein vs. UniProt/SwissProt
Match: sp|Q9W5E1|RBX1A_DROME (RING-box protein 1A OS=Drosophila melanogaster OX=7227 GN=Roc1a PE=1 SV=1)

HSP 1 Score: 191.43 bits (485), Expect = 6.541e-63
Identity = 92/108 (85.19%), Postives = 97/108 (89.81%), Query Frame = 3 
Query:   69 MEVDELN-AAGASGNNPTKKRFEIKKWNAVALWAWDIVVDNCAICRNHIMDLCIECQANHATATSEECTVAWGVCNHAFHFHCISRWLKTRQVCPLDNREWEFQKYGH 389
            MEVDE      +S +   KKRFE+KKWNAVALWAWDIVVDNCAICRNHIMDLCIECQAN A+ATSEECTVAWGVCNHAFHFHCISRWLKTRQVCPLDNREW+FQKYGH
Sbjct:    1 MEVDEDGYEVPSSSSKGDKKRFEVKKWNAVALWAWDIVVDNCAICRNHIMDLCIECQANQASATSEECTVAWGVCNHAFHFHCISRWLKTRQVCPLDNREWDFQKYGH 108
[Close]
BLAST of Ring box protein vs. UniProt/SwissProt
Match: sp|Q23457|RBX1_CAEEL (RING-box protein 1 OS=Caenorhabditis elegans OX=6239 GN=rbx-1 PE=1 SV=1)

HSP 1 Score: 184.111 bits (466), Expect = 5.643e-60
Identity = 88/110 (80.00%), Postives = 93/110 (84.55%), Query Frame = 3 
Query:   60 STAMEVDELNAAGASGNNPTKKRFEIKKWNAVALWAWDIVVDNCAICRNHIMDLCIECQANHATATSEECTVAWGVCNHAFHFHCISRWLKTRQVCPLDNREWEFQKYGH 389
            STAMEV+E      + N   KKRFE+KKW+AVALWAWDI VDNCAICRNHIMDLCIECQAN A    +ECTVAWG CNHAFHFHCISRWLKTRQVCPLDNREWEFQKYGH
Sbjct:    7 STAMEVEE------ATNQTVKKRFEVKKWSAVALWAWDIQVDNCAICRNHIMDLCIECQANQAAGLKDECTVAWGNCNHAFHFHCISRWLKTRQVCPLDNREWEFQKYGH 110
[Close]
BLAST of Ring box protein vs. TrEMBL
Match: C3XXN0 (RING-type domain-containing protein OS=Branchiostoma floridae OX=7739 GN=BRAFLDRAFT_113519 PE=4 SV=1)

HSP 1 Score: 205.682 bits (522), Expect = 6.122e-66
Identity = 94/111 (84.68%), Postives = 101/111 (90.99%), Query Frame = 3 
Query:   57 MSTAMEVDELNAAGASGNNPTKKRFEIKKWNAVALWAWDIVVDNCAICRNHIMDLCIECQANHATATSEECTVAWGVCNHAFHFHCISRWLKTRQVCPLDNREWEFQKYGH 389
            M+TAMEVD   +   + + P +KRFE+KKWNAVALWAWDIVVDNCAICRNHIMDLCIECQAN A+ATSEECTVAWGVCNHAFHFHCISRWLKTRQVCPLDNREWEFQKYGH
Sbjct:    1 MATAMEVDPPASTSGASSKPAQKRFEVKKWNAVALWAWDIVVDNCAICRNHIMDLCIECQANQASATSEECTVAWGVCNHAFHFHCISRWLKTRQVCPLDNREWEFQKYGH 111
[Close]
BLAST of Ring box protein vs. TrEMBL
Match: Q0GFG6 (Ring box protein 1 OS=Branchiostoma belcheri tsingtauense OX=155462 GN=Rbx1 PE=2 SV=1)

HSP 1 Score: 205.682 bits (522), Expect = 6.122e-66
Identity = 94/111 (84.68%), Postives = 101/111 (90.99%), Query Frame = 3 
Query:   57 MSTAMEVDELNAAGASGNNPTKKRFEIKKWNAVALWAWDIVVDNCAICRNHIMDLCIECQANHATATSEECTVAWGVCNHAFHFHCISRWLKTRQVCPLDNREWEFQKYGH 389
            M+TAMEVD   +   + + P +KRFE+KKWNAVALWAWDIVVDNCAICRNHIMDLCIECQAN A+ATSEECTVAWGVCNHAFHFHCISRWLKTRQVCPLDNREWEFQKYGH
Sbjct:    1 MATAMEVDPPASTSGASSKPAQKRFEVKKWNAVALWAWDIVVDNCAICRNHIMDLCIECQANQASATSEECTVAWGVCNHAFHFHCISRWLKTRQVCPLDNREWEFQKYGH 111
[Close]
BLAST of Ring box protein vs. TrEMBL
Match: A0A397IHM4 (RING-type domain-containing protein OS=Diversispora epigaea OX=1348612 GN=Glove_226g30 PE=4 SV=1)

HSP 1 Score: 202.216 bits (513), Expect = 1.960e-64
Identity = 96/119 (80.67%), Postives = 102/119 (85.71%), Query Frame = 3 
Query:   39 LVINF*MSTAMEVDELNAAGASGN--NPTKKRFEIKKWNAVALWAWDIVVDNCAICRNHIMDLCIECQANHATATSEECTVAWGVCNHAFHFHCISRWLKTRQVCPLDNREWEFQKYGH 389
            L I   MST ME+D    + ASG   +  KKRFE+KKWNAVALWAWDIVVDNCAICRNHIMDLCIECQAN A+ATSEECTVAWG+CNHAFHFHCISRWLKTRQVCPLDNREWEFQKYG 
Sbjct:   11 LKIQILMSTPMEIDLPAGSKASGKAKDTGKKRFEVKKWNAVALWAWDIVVDNCAICRNHIMDLCIECQANQASATSEECTVAWGICNHAFHFHCISRWLKTRQVCPLDNREWEFQKYGR 129
[Close]
BLAST of Ring box protein vs. TrEMBL
Match: A0A1S3H229 (RING-box protein 1 OS=Lingula unguis OX=7574 GN=LOC106150763 PE=4 SV=1)

HSP 1 Score: 201.83 bits (512), Expect = 2.135e-64
Identity = 94/112 (83.93%), Postives = 104/112 (92.86%), Query Frame = 3 
Query:   57 MSTAMEVD-ELNAAGASGNNPTKKRFEIKKWNAVALWAWDIVVDNCAICRNHIMDLCIECQANHATATSEECTVAWGVCNHAFHFHCISRWLKTRQVCPLDNREWEFQKYGH 389
            M+ AME+D E+ ++ A+  + +KKRFE+KKWNAVALWAWDIVVDNCAICRNHIMDLCIECQAN A+ATSEECTVAWGVCNHAFHFHCISRWLKTRQVCPLDNREWEFQKYGH
Sbjct:    1 MAAAMEIDDEVQSSNAADKSGSKKRFEVKKWNAVALWAWDIVVDNCAICRNHIMDLCIECQANQASATSEECTVAWGVCNHAFHFHCISRWLKTRQVCPLDNREWEFQKYGH 112
[Close]
BLAST of Ring box protein vs. TrEMBL
Match: A0A5E4Q9E7 (RING-type domain-containing protein OS=Leptidea sinapis OX=189913 GN=LSINAPIS_LOCUS6704 PE=4 SV=1)

HSP 1 Score: 201.06 bits (510), Expect = 3.308e-64
Identity = 95/113 (84.07%), Postives = 102/113 (90.27%), Query Frame = 3 
Query:   57 MSTAMEVDE--LNAAGASGNNPTKKRFEIKKWNAVALWAWDIVVDNCAICRNHIMDLCIECQANHATATSEECTVAWGVCNHAFHFHCISRWLKTRQVCPLDNREWEFQKYGH 389
            M++AM+VDE  +  A  S +   KKRFE+KKWNAVALWAWDIVVDNCAICRNHIMDLCIECQAN A+ATSEECTVAWGVCNHAFHFHCISRWLKTRQVCPLDNREWEFQKYGH
Sbjct:    1 MASAMDVDEEEVEMASTSSSKGDKKRFEVKKWNAVALWAWDIVVDNCAICRNHIMDLCIECQANQASATSEECTVAWGVCNHAFHFHCISRWLKTRQVCPLDNREWEFQKYGH 113
[Close]
BLAST of Ring box protein vs. Ensembl Cavefish
Match: rbx1 (ring-box 1, E3 ubiquitin protein ligase [Source:ZFIN;Acc:ZDB-GENE-041008-106])

HSP 1 Score: 189.504 bits (480), Expect = 6.928e-63
Identity = 93/125 (74.40%), Postives = 102/125 (81.60%), Query Frame = 3 
Query:   15 KISKFYCFLVINF*MSTAMEVDELNAAGASGNNPTKKRFEIKKWNAVALWAWDIVVDNCAICRNHIMDLCIECQANHATATSEECTVAWGVCNHAFHFHCISRWLKTRQVCPLDNREWEFQKYGH 389
            ++S+  C   +N      ++      +GAS     KKRFE+KKWNAVALWAWDIVVDNCAICRNHIMDLCIECQAN A+ATSEECTVAWGVCNHAFHFHCISRWLKTRQVCPLDNREWEFQKYGH
Sbjct:    4 RLSREICGSAVNHGGCYGVDTPSGTNSGAS-----KKRFEVKKWNAVALWAWDIVVDNCAICRNHIMDLCIECQANQASATSEECTVAWGVCNHAFHFHCISRWLKTRQVCPLDNREWEFQKYGH 123
[Close]
BLAST of Ring box protein vs. Ensembl Cavefish
Match: rnf7 (ring finger protein 7 [Source:NCBI gene;Acc:103026563])

HSP 1 Score: 97.0561 bits (240), Expect = 1.772e-26
Identity = 44/88 (50.00%), Postives = 58/88 (65.91%), Query Frame = 3 
Query:  123 KRFEIKKWNAVALWAWDIVVDNCAICRNHIMDLCIECQANHATATSEECTVAWGVCNHAFHFHCISRWLKTRQVCPLDNREWEFQKYG 386
            K F +KKWNAVA+W+WD+  D CAICR  +MD C+ CQA +     E+C V WG CNH+FH  C+S W+K    CPL  ++W  Q+ G
Sbjct:   34 KMFSLKKWNAVAMWSWDVECDTCAICRVQVMDACLRCQAEN---KQEDCVVVWGECNHSFHNCCMSLWVKQNNRCPLCQQDWVVQRIG 118
[Close]
BLAST of Ring box protein vs. Ensembl Cavefish
Match: anapc11 (anaphase promoting complex subunit 11 [Source:NCBI gene;Acc:103021554])

HSP 1 Score: 73.1738 bits (178), Expect = 1.728e-17
Identity = 34/88 (38.64%), Postives = 52/88 (59.09%), Query Frame = 3 
Query:  126 RFEIKKWNAVALWAWDIVVDNCAICRNHIMDLCIECQANHATATSEECTVAWGVCNHAFHFHCISRWLKTRQV---CPLDNREWEFQK 380
            + +IK+WN VA W W    +NC ICR      C +C+        ++C + WG C+H FH HCI +WL ++QV   CP+  +EW+F++
Sbjct:    2 KVKIKQWNGVASWLWVANDENCGICRAPFNGCCPDCKV-----PGDDCPLVWGQCSHCFHMHCILKWLNSQQVQQQCPMCRQEWKFKE 84
[Close]
BLAST of Ring box protein vs. Ensembl Sea Lamprey
Match: rbx1 (ring-box 1, E3 ubiquitin protein ligase [Source:ZFIN;Acc:ZDB-GENE-041008-106])

HSP 1 Score: 169.859 bits (429), Expect = 2.328e-56
Identity = 80/83 (96.39%), Postives = 82/83 (98.80%), Query Frame = 3 
Query:  141 KWNAVALWAWDIVVDNCAICRNHIMDLCIECQANHATATSEECTVAWGVCNHAFHFHCISRWLKTRQVCPLDNREWEFQKYGH 389
            +WNAVALWAWDIVVDNCAICRNHIMDLCIECQAN A+ATSEECTVAWGVCNHAFHFHCISRWLKTRQVCPLDNREWEFQKYGH
Sbjct:    1 QWNAVALWAWDIVVDNCAICRNHIMDLCIECQANQASATSEECTVAWGVCNHAFHFHCISRWLKTRQVCPLDNREWEFQKYGH 83
[Close]
BLAST of Ring box protein vs. Ensembl Yeast
Match: HRT1 (RING-H2 domain core subunit of multiple ubiquitin ligase complexes; subunit of Skp1-Cullin-F-box (SCF) that tethers the Cdc34p (E2) and Cdc53p (cullin) SCF subunits, and is required for degradation of Gic2p, Far1p, Sic1p and Cln2p; subunit of the Rtt101p-Mms1p-Mms22p ubiquitin ligase that stabilizes replication forks after DNA lesions; subunit of the Cul3p-Elc1p-Ela1p ubiquitin ligase involved in Rpb1p degradation as part of transcription-coupled repair [Source:SGD;Acc:S000005493])

HSP 1 Score: 140.969 bits (354), Expect = 1.424e-44
Identity = 68/114 (59.65%), Postives = 79/114 (69.30%), Query Frame = 3 
Query:   69 MEVDE---LNAAGASGNNPT----KKRFEIKKWNAVALWAWDIVVDNCAICRNHIMDLCIECQANHATATSEECTVAWGVCNHAFHFHCISRWLKTRQVCPLDNREWEFQKYGH 389
            M+VDE    N A +S  +      KKRFEIKKW AVA W+WDI VDNCAICRNHIM+ CIECQ    T T  EC  AWGVCNHAFH HCI++W+KTR  CPLDN+ W+  + G 
Sbjct:    8 MDVDEDESQNIAQSSNQSAPVETKKKRFEIKKWTAVAFWSWDIAVDNCAICRNHIMEPCIECQPKAMTDTDNECVAAWGVCNHAFHLHCINKWIKTRDACPLDNQPWQLARCGR 121
[Close]
BLAST of Ring box protein vs. Ensembl Yeast
Match: YOL134C_mRNA (Dubious open reading frame; unlikely to encode a functional protein, based on available experimental and comparative sequence data; partially overlaps HRT1, a verified gene that encodes an SCF ubiquitin ligase subunit [Source:SGD;Acc:S000005494])

HSP 1 Score: 52.7582 bits (125), Expect = 3.612e-10
Identity = 31/53 (58.49%), Postives = 36/53 (67.92%), Query Frame = -3 
Query:   86 HSMHKSMI*LRQIAQLSTTMSQAQSATAFHFLISNLFFV----GLFPEAPAAF 232
            HSMH S+I   QIAQLST +S  Q+ATA HFLISNLFF+     L+ E  A F
Sbjct:    6 HSMHGSIIWFLQIAQLSTAISHDQNATAVHFLISNLFFLVSTGALWFELCAIF 58
[Close]
BLAST of Ring box protein vs. Ensembl Yeast
Match: APC11 (Catalytic core subunit, Anaphase-Promoting Complex/Cyclosome (APC/C); which is a ubiquitin-protein ligase required for degradation of anaphase inhibitors, including mitotic cyclins, during the metaphase/anaphase transition; contains a RING-H2 domain that is required for activity [Source:SGD;Acc:S000002166])

HSP 1 Score: 48.1358 bits (113), Expect = 3.151e-8
Identity = 28/80 (35.00%), Postives = 40/80 (50.00%), Query Frame = 3 
Query:  183 DNCAICRNHIMDLCIECQANHATATSEECTVAWGVCNHAFHFHCISRWLKT---RQVCPLDNREWEFQKYGH**DGLKIN 413
            D C ICR      C  C+        ++C +  G+C+H FH HCI RWL T   + +CP+  + ++ QK      GL IN
Sbjct:   39 DVCGICRASYNGTCPSCKF-----PGDQCPLVIGLCHHNFHDHCIYRWLDTPTSKGLCPMCRQTFQLQK------GLAIN 107
[Close]
BLAST of Ring box protein vs. Ensembl Nematostella
Match: EDO37895 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SEK8])

HSP 1 Score: 193.356 bits (490), Expect = 6.493e-65
Identity = 91/106 (85.85%), Postives = 97/106 (91.51%), Query Frame = 3 
Query:   69 MEVDELNAAGASGNNPTKKRFEIKKWNAVALWAWDIVVDNCAICRNHIMDLCIECQANHATATSEECTVAWGVCNHAFHFHCISRWLKTRQVCPLDNREWEFQKYG 386
            M+VD+  A  ++   P KKRFE+KKWNAVALWAWDIVVDNCAICRNHIMDLCIECQAN A+ATSEECTVAWGVCNHAFHFHCISRWLKTRQVCPLDNREWEFQKYG
Sbjct:    7 MDVDD-TAQPSTSAGPAKKRFEVKKWNAVALWAWDIVVDNCAICRNHIMDLCIECQANQASATSEECTVAWGVCNHAFHFHCISRWLKTRQVCPLDNREWEFQKYG 111
[Close]
BLAST of Ring box protein vs. Ensembl Nematostella
Match: EDO29393 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7T3S1])

HSP 1 Score: 131.724 bits (330), Expect = 8.203e-41
Identity = 64/97 (65.98%), Postives = 71/97 (73.20%), Query Frame = 3 
Query:   69 MEVDELNAAGASGNNPTKKRFEIKKWNAVALWAWDIVVDNCAICRNHIMDLCIECQANHATATSEECTVAWGVCNHAFHFHCISRWLKTRQVCPLDN 359
            M+VD+  A  ++   P KKRFE+KKWNAVALWAWDIVVDNCAICRNHIMDLC         A   +C +AW V  HAFHFHCISRWLKT QVCPL N
Sbjct:    1 MDVDD-TAQPSTSAGPAKKRFEVKKWNAVALWAWDIVVDNCAICRNHIMDLCKFFMVGSLCADLTKCLIAWQVVYHAFHFHCISRWLKTSQVCPLYN 96
[Close]
BLAST of Ring box protein vs. Ensembl Nematostella
Match: EDO46054 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RR57])

HSP 1 Score: 97.4413 bits (241), Expect = 2.191e-27
Identity = 43/94 (45.74%), Postives = 61/94 (64.89%), Query Frame = 3 
Query:  108 NNPTKKRFEIKKWNAVALWAWDIVVDNCAICRNHIMDLCIECQANHATATSEECTVAWGVCNHAFHFHCISRWLKTRQVCPLDNREWEFQKYGH 389
            +  ++K F +KKWNA+A+W+WD+  D CAICR  +MD C+ CQ+++     EEC V WG CNH+FH  C+S W+     CPL  +EW  Q+ G 
Sbjct:    9 DKESQKMFSLKKWNAIAMWSWDVECDTCAICRVQVMDACLRCQSDNK---QEECVVVWGECNHSFHNCCMSLWVVQNNRCPLCQQEWVVQRIGR 99
[Close]
BLAST of Ring box protein vs. Ensembl Nematostella
Match: EDO36209 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SJC0])

HSP 1 Score: 72.4034 bits (176), Expect = 1.076e-17
Identity = 34/89 (38.20%), Postives = 50/89 (56.18%), Query Frame = 3 
Query:  123 KRFEIKKWNAVALWAWDIVVDNCAICRNHIMDLCIECQANHATATSEECTVAWGVCNHAFHFHCISRWLKT---RQVCPLDNREWEFQK 380
            KRF   +W  VA W W    DNC ICR      C +C+        ++C + WG C+H FH HCI +WL +   +Q+CP+  +EW+F++
Sbjct:    6 KRFHSGRWVGVATWKWMANDDNCGICRMPFDGCCPDCKV-----PGDDCPLVWGRCSHVFHMHCILKWLNSQLHQQLCPMCRQEWQFKE 89
[Close]
BLAST of Ring box protein vs. Ensembl Medaka
Match: rbx1 (ring-box 1, E3 ubiquitin protein ligase [Source:ZFIN;Acc:ZDB-GENE-041008-106])

HSP 1 Score: 129.028 bits (323), Expect = 1.894e-39
Identity = 62/85 (72.94%), Postives = 71/85 (83.53%), Query Frame = 3 
Query:   57 MSTAMEVDELNAAGASGNNPTKKRFEIKKWNAVALWAWDIVVDNCAICRNHIMDLCIECQANHATATSEECTVAWGVCNHAFHFH 311
            M+ AM+VD  + A +     +KKRFE+KKWNAVALWAWDIVVDNCAICRNHIMDLCIECQAN A+ATSEECTVAWGVCN +F  +
Sbjct:    1 MAAAMDVDTPSGANSGS---SKKRFEVKKWNAVALWAWDIVVDNCAICRNHIMDLCIECQANQASATSEECTVAWGVCNVSFQLN 82
[Close]
BLAST of Ring box protein vs. Ensembl Medaka
Match: rnf7 (ring finger protein 7 [Source:NCBI gene;Acc:101175180])

HSP 1 Score: 100.138 bits (248), Expect = 8.029e-28
Identity = 45/101 (44.55%), Postives = 62/101 (61.39%), Query Frame = 3 
Query:   84 LNAAGASGNNPTKKRFEIKKWNAVALWAWDIVVDNCAICRNHIMDLCIECQANHATATSEECTVAWGVCNHAFHFHCISRWLKTRQVCPLDNREWEFQKYG 386
            L+   +     + K F +KKWNAVA+W+WD+  D CAICR  +MD C+ CQA +     E+C V WG CNH+FH  C+S W+K    CPL  ++W  Q+ G
Sbjct:   12 LSHTSSGSKTGSDKMFSLKKWNAVAMWSWDVECDTCAICRVQVMDACLRCQAEN---KQEDCVVVWGECNHSFHNCCMSLWVKQNNRCPLCQQDWVVQRIG 109
[Close]
BLAST of Ring box protein vs. Ensembl Medaka
Match: anapc11 (anaphase promoting complex subunit 11 [Source:NCBI gene;Acc:101154922])

HSP 1 Score: 72.7886 bits (177), Expect = 2.332e-17
Identity = 34/88 (38.64%), Postives = 52/88 (59.09%), Query Frame = 3 
Query:  126 RFEIKKWNAVALWAWDIVVDNCAICRNHIMDLCIECQANHATATSEECTVAWGVCNHAFHFHCISRWLKTRQV---CPLDNREWEFQK 380
            + +IK+WN VA W W    +NC ICR      C +C+        ++C + WG C+H FH HCI +WL ++QV   CP+  +EW+F++
Sbjct:    2 KVKIKQWNGVASWLWVANDENCGICRMPFNGCCPDCKV-----PGDDCPLVWGQCSHCFHMHCILKWLNSQQVQQQCPMCRQEWKFKE 84
[Close]
BLAST of Ring box protein vs. Planmine SMEST
Match: SMESG000036014.1 (SMESG000036014.1)

HSP 1 Score: 232.646 bits (592), Expect = 2.954e-80
Identity = 111/111 (100.00%), Postives = 111/111 (100.00%), Query Frame = 3 
Query:   57 MSTAMEVDELNAAGASGNNPTKKRFEIKKWNAVALWAWDIVVDNCAICRNHIMDLCIECQANHATATSEECTVAWGVCNHAFHFHCISRWLKTRQVCPLDNREWEFQKYGH 389
            MSTAMEVDELNAAGASGNNPTKKRFEIKKWNAVALWAWDIVVDNCAICRNHIMDLCIECQANHATATSEECTVAWGVCNHAFHFHCISRWLKTRQVCPLDNREWEFQKYGH
Sbjct:    1 MSTAMEVDELNAAGASGNNPTKKRFEIKKWNAVALWAWDIVVDNCAICRNHIMDLCIECQANHATATSEECTVAWGVCNHAFHFHCISRWLKTRQVCPLDNREWEFQKYGH 111
[Close]
BLAST of Ring box protein vs. Planmine SMEST
Match: SMESG000017110.1 (SMESG000017110.1)

HSP 1 Score: 85.5001 bits (210), Expect = 2.064e-22
Identity = 38/90 (42.22%), Postives = 55/90 (61.11%), Query Frame = 3 
Query:  117 TKKRFEIKKWNAVALWAWDIVVDNCAICRNHIMDLCIECQANHATATSEECTVAWGVCNHAFHFHCISRWLKTRQVCPLDNREWEFQKYG 386
             +  F +K+WN V LW+W+   +NCAICRN +M+ C+ CQ ++      EC + WG CNH FH  CIS+W+K    CPL  + W  ++ G
Sbjct:   11 NQNLFTLKRWNLVGLWSWECTSENCAICRNGVMEPCVHCQNDNRLT---ECILVWGECNHVFHNCCISQWIKKNNNCPLCQQIWNVRRIG 97
The following BLAST results are available for this feature:
BLAST of Ring box protein vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5
Match NameE-valueIdentityDescription
RBX19.808e-6582.88ring-box 1 [Source:HGNC Symbol;Acc:HGNC:9928][more]
RNF72.142e-2650.00ring finger protein 7 [Source:HGNC Symbol;Acc:HGNC... [more]
RNF77.954e-1842.05ring finger protein 7 [Source:HGNC Symbol;Acc:HGNC... [more]
ANAPC115.429e-1638.64anaphase promoting complex subunit 11 [Source:HGNC... [more]
ANAPC115.429e-1638.64anaphase promoting complex subunit 11 [Source:HGNC... [more]
back to top
BLAST of Ring box protein vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 5
Match NameE-valueIdentityDescription
rbx-14.436e-6180.00RING-box protein 1 [Source:UniProtKB/Swiss-Prot;A... [more]
rbx-14.436e-6180.00RING-box protein 1 [Source:UniProtKB/Swiss-Prot;A... [more]
rbx-21.063e-2448.28Yeast RBX (Ring finger protein) homolog [Source:U... [more]
apc-111.983e-831.11Anaphase-promoting complex subunit 11 [Source:Uni... [more]
apc-111.983e-831.11Anaphase-promoting complex subunit 11 [Source:Uni... [more]
back to top
BLAST of Ring box protein vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Roc1a6.525e-6485.19gene:FBgn0025638 transcript:FBtr0343564[more]
Roc1a6.525e-6485.19gene:FBgn0025638 transcript:FBtr0070122[more]
Roc1a3.557e-5867.65gene:FBgn0025638 transcript:FBtr0308651[more]
Roc1b1.675e-4464.08gene:FBgn0040291 transcript:FBtr0072547[more]
Roc29.099e-2845.28gene:FBgn0044020 transcript:FBtr0302211[more]
back to top
BLAST of Ring box protein vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
rbx19.784e-6683.78ring-box 1, E3 ubiquitin protein ligase [Source:ZF... [more]
rbx17.265e-3896.61ring-box 1, E3 ubiquitin protein ligase [Source:ZF... [more]
rnf71.750e-2650.00ring finger protein 7 [Source:ZFIN;Acc:ZDB-GENE-05... [more]
anapc112.062e-1738.64APC11 anaphase promoting complex subunit 11 homolo... [more]
anapc112.062e-1738.64APC11 anaphase promoting complex subunit 11 homolo... [more]
back to top
BLAST of Ring box protein vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 4
Match NameE-valueIdentityDescription
RBX11.542e-6683.19ring-box 1, E3 ubiquitin protein ligase [Source:NC... [more]
RBX11.407e-6483.49ring-box 1, E3 ubiquitin protein ligase [Source:NC... [more]
rnf72.647e-2749.48ring finger protein 7 [Source:NCBI gene;Acc:100135... [more]
gnb1l1.536e-1639.77guanine nucleotide binding protein (G protein), be... [more]
back to top
BLAST of Ring box protein vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Rbx16.734e-6582.88ring-box 1 [Source:MGI Symbol;Acc:MGI:1891829][more]
Rbx17.841e-3896.61ring-box 1 [Source:MGI Symbol;Acc:MGI:1891829][more]
Rbx19.521e-3871.76ring-box 1 [Source:MGI Symbol;Acc:MGI:1891829][more]
Rnf71.640e-2650.00ring finger protein 7 [Source:MGI Symbol;Acc:MGI:1... [more]
Gm70753.481e-2547.73predicted gene 7075 [Source:MGI Symbol;Acc:MGI:364... [more]
back to top
BLAST of Ring box protein vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|Q8QG64|RBX1_SALSA4.460e-6583.78RING-box protein 1 OS=Salmo salar OX=8030 GN=rbx1 ... [more]
sp|P62878|RBX1_MOUSE4.710e-6482.88E3 ubiquitin-protein ligase RBX1 OS=Mus musculus O... [more]
sp|P62877|RBX1_HUMAN4.710e-6482.88E3 ubiquitin-protein ligase RBX1 OS=Homo sapiens O... [more]
sp|Q9W5E1|RBX1A_DROME6.541e-6385.19RING-box protein 1A OS=Drosophila melanogaster OX=... [more]
sp|Q23457|RBX1_CAEEL5.643e-6080.00RING-box protein 1 OS=Caenorhabditis elegans OX=62... [more]
back to top
BLAST of Ring box protein vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
C3XXN06.122e-6684.68RING-type domain-containing protein OS=Branchiosto... [more]
Q0GFG66.122e-6684.68Ring box protein 1 OS=Branchiostoma belcheri tsing... [more]
A0A397IHM41.960e-6480.67RING-type domain-containing protein OS=Diversispor... [more]
A0A1S3H2292.135e-6483.93RING-box protein 1 OS=Lingula unguis OX=7574 GN=LO... [more]
A0A5E4Q9E73.308e-6484.07RING-type domain-containing protein OS=Leptidea si... [more]
back to top
BLAST of Ring box protein vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 3
Match NameE-valueIdentityDescription
rbx16.928e-6374.40ring-box 1, E3 ubiquitin protein ligase [Source:ZF... [more]
rnf71.772e-2650.00ring finger protein 7 [Source:NCBI gene;Acc:103026... [more]
anapc111.728e-1738.64anaphase promoting complex subunit 11 [Source:NCBI... [more]
back to top
BLAST of Ring box protein vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 1
Match NameE-valueIdentityDescription
rbx12.328e-5696.39ring-box 1, E3 ubiquitin protein ligase [Source:ZF... [more]
back to top
BLAST of Ring box protein vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 3
Match NameE-valueIdentityDescription
HRT11.424e-4459.65RING-H2 domain core subunit of multiple ubiquitin ... [more]
YOL134C_mRNA3.612e-1058.49Dubious open reading frame; unlikely to encode a f... [more]
APC113.151e-835.00Catalytic core subunit, Anaphase-Promoting Complex... [more]
back to top
BLAST of Ring box protein vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 4
Match NameE-valueIdentityDescription
EDO378956.493e-6585.85Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO293938.203e-4165.98Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO460542.191e-2745.74Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO362091.076e-1738.20Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
back to top
BLAST of Ring box protein vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 3
Match NameE-valueIdentityDescription
rbx11.894e-3972.94ring-box 1, E3 ubiquitin protein ligase [Source:ZF... [more]
rnf78.029e-2844.55ring finger protein 7 [Source:NCBI gene;Acc:101175... [more]
anapc112.332e-1738.64anaphase promoting complex subunit 11 [Source:NCBI... [more]
back to top
BLAST of Ring box protein vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 2
Match NameE-valueIdentityDescription
SMESG000036014.12.954e-80100.00SMESG000036014.1[more]
SMESG000017110.12.064e-2242.22SMESG000017110.1[more]
back to top
Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30013600 ID=SMED30013600|Name=Ring box protein|organism=Schmidtea mediterranea sexual|type=transcript|length=459bp
ATCTATTGTTTTCAAAAATTTCAAAATTTTATTGTTTTTTAGTTATTAAT
TTCTGAATGTCAACTGCTATGGAAGTTGATGAATTAAACGCTGCAGGAGC
TTCTGGAAACAATCCAACGAAAAAAAGATTTGAAATTAAGAAATGGAACG
CAGTAGCACTTTGGGCTTGGGACATAGTAGTAGATAATTGTGCAATTTGC
CGCAATCATATCATGGATTTATGCATTGAATGTCAGGCTAATCATGCAAC
GGCAACAAGTGAAGAATGCACAGTCGCATGGGGAGTTTGTAATCACGCTT
TTCATTTTCACTGTATATCAAGATGGTTGAAAACAAGACAAGTATGTCCT
TTAGATAATCGAGAATGGGAATTTCAAAAATATGGACATTGATAAGATGG
GTTGAAAATTAATTATAATATGTAATGTTAGATAAATAATTAATTTATCT
TGAAAAAAA
back to top

protein sequence of SMED30013600-orf-1

>SMED30013600-orf-1 ID=SMED30013600-orf-1|Name=SMED30013600-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=112bp
MSTAMEVDELNAAGASGNNPTKKRFEIKKWNAVALWAWDIVVDNCAICRN
HIMDLCIECQANHATATSEECTVAWGVCNHAFHFHCISRWLKTRQVCPLD
NREWEFQKYGH*
back to top
Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000418head
PLANA:0000429neoblast
Vocabulary: INTERPRO
TermDefinition
IPR024766Znf_RING_H2
IPR013083Znf_RING/FYVE/PHD
IPR001841Znf_RING
Vocabulary: molecular function
TermDefinition
GO:0008270zinc ion binding
GO:0005515protein binding
GO:0019788NEDD8 transferase activity
GO:0046872metal ion binding
Vocabulary: cellular component
TermDefinition
GO:0005634nucleus
GO:0005737cytoplasm
GO:0019005SCF ubiquitin ligase complex
GO:0031463Cul3-RING ubiquitin ligase complex
GO:0031464Cul4A-RING E3 ubiquitin ligase complex
GO:0031465Cul4B-RING E3 ubiquitin ligase complex
GO:0031467Cul7-RING ubiquitin ligase complex
Vocabulary: biological process
TermDefinition
GO:0006513protein monoubiquitination
GO:0016567protein ubiquitination
GO:0031146SCF-dependent proteasomal ubiquitin-dependent protein catabolic process
GO:0043161proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0045116protein neddylation
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR013083Zinc finger, RING/FYVE/PHD-typeGENE3DG3DSA:3.30.40.10coord: 12..111
e-value: 4.1E-35
score: 121.9
IPR024766Zinc finger, RING-H2-typePFAMPF12678zf-rbx1coord: 43..101
e-value: 4.6E-25
score: 87.7
NoneNo IPR availablePANTHERPTHR11210:SF48coord: 15..111
NoneNo IPR availablePANTHERPTHR11210RING BOXcoord: 15..111
NoneNo IPR availableCDDcd16485mRING-H2-C3H2C2D_RBX1coord: 43..104
e-value: 1.65944E-42
score: 131.723
NoneNo IPR availableSUPERFAMILYSSF57850RING/U-boxcoord: 23..108
IPR001841Zinc finger, RING-typePROSITEPS50089ZF_RING_2coord: 56..101
score: 9.273