Actin-related protein 8

Overview
NameActin-related protein 8
Smed IDSMED30013599
Length (bp)2449
Neoblast Clusters

Zeng et. al., 2018




▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 



 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)




Explore this single cell expression dataset with our NB Cluster Shiny App




 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of Actin-related protein 8 (SMED30013599) t-SNE clustered cells

Violin plots show distribution of expression levels for Actin-related protein 8 (SMED30013599) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of Actin-related protein 8 (SMED30013599) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for Actin-related protein 8 (SMED30013599) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017




Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020




SMED30013599

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 3

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
parenchymaSMED30013599h1SMcG0005186 dd_Smed_v4_3782_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
head regionSMED30013599h1SMcG0005186 OX_Smed_1.0.19360ox_Smed_v2PMID:24238224
Kao et al., 2013
whole organism asexual adult RNA-sequencing evidence
epidermisSMED30013599h1SMcG0005186 dd_Smed_v4_3782_0_1dd_Smed_v4PMID:28292427
Wurtzel et al., 2017
whole organism asexual adult single-cell RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
BLAST of Actin-related protein 8 vs. Ensembl Human
Match: ACTR8 (actin related protein 8 [Source:HGNC Symbol;Acc:HGNC:14672])

HSP 1 Score: 164.466 bits (415), Expect = 4.898e-42
Identity = 128/418 (30.62%), Postives = 203/418 (48.56%), Query Frame = 1
Query:   85 IIVIHPSATKLRFGRSNDSEPIIIPHCIARKCKIISKVIRQPKIPDNRASTLLNTKFN---------NAIKLASIAMKSSSI-----------EVLQPFKEQ--PTINELIHMNKQYLKXXXXXXXXXXHRVYSEEFYIGKEALEVPIEANYNLHWPFWDDKI----SDKYSKTAAVKDLEDIWRMGIEKSLKIPSEDLANYRIILVISDLIIRSEIRWIIEMLINELKFSNIVLQQENVCITYSTGLPTACVVNMHENSISISCVEEGISIPEGRIKLLYGTSDILCLFHSLLIRIGFP--KTAIESYSDYQGVQSIEELFATACELIPSNESKASKLNGNRKSI-DPNGRIRCQSIDMYIGSEAIIAGLALFHPSLICKDSPKY-QFQHNLADESEPDDPFDDLYLTLTSRDRKKQ 1248
            IIVIHP +T LR GR+ D+ P  IPH IAR+ K       Q   P  + S LL    N         N +K+   A+ S  +           E  + + +Q  P I +    NK              +  +  E+ +G+EAL V     YN+HWP    ++        S TA + D+E IW   I+K L+IP +DL  YR IL+I D+  +  ++ ++ M++ ++ FS IV+ QE+VC TY +GL + C+V++ +   S+ CVE+G+S    R+ L YG SD+   F+ L+ R GFP  +  + +  D   +Q ++E F   C L    +   S L  +   I  P+           +G E + A +ALF+P+       K    QH    + +P+DP D+ YL L ++ +++Q
Sbjct:   48 IIVIHPGSTTLRIGRATDTLPASIPHVIARRHK-------QQGQPLYKDSWLLREGLNKPESNEQRQNGLKMVDQAIWSKKMSNGTRRIPVSPEQARSYNKQMRPAILDHCSGNK------------WTNTSHHPEYLVGEEALYVNPLDCYNIHWPIRRGQLNIHPGPGGSLTAVLADIEVIWSHAIQKYLEIPLKDLKYYRCILLIPDIYNKQHVKELVNMILMKMGFSGIVVHQESVCATYGSGLSSTCIVDVGDQKTSVCCVEDGVSHRNTRLCLAYGGSDVSRCFYWLMQRAGFPYRECQLTNKMDCLLLQHLKETF---CHL----DQDISGLQDHEFQIRHPDSPALL--YQFRLGDEKLQAPMALFYPATFGIVGQKMTTLQHR--SQGDPEDPHDEHYL-LATQSKQEQ 434          

HSP 2 Score: 53.1434 bits (126), Expect = 1.690e-6
Identity = 39/130 (30.00%), Postives = 64/130 (49.23%), Query Frame = 1
Query: 1486 NKALPLNDAIVKSINKSLSSLAVVIDNITETSQQLCSVILA-GEPIEFPGCVELLE----NSLKPSLSQCGE-VEVIHNDFTDGISAHSAAWKGASMITLVGYCDDLWISGKDWNKYGSRAIREKAPFLW 1857
             KAL L+ AI+ SI+   S          +T +++ S IL  G  + F    E L+    N + PS  +  E V+VI       +     AWKG +++  +    +LWI  ++W ++G R +RE+A F+W
Sbjct:  506 GKALGLDKAILHSIDCCSSD---------DTKKKMYSSILVVGGGLMFHKAQEFLQHRILNKMPPSFRRIIENVDVITR--PKDMDPRLIAWKGGAVLACLDTTQELWIYQREWQRFGVRMLRERAAFVW 624          
BLAST of Actin-related protein 8 vs. Ensembl Human
Match: ACTR8 (actin related protein 8 [Source:HGNC Symbol;Acc:HGNC:14672])

HSP 1 Score: 139.813 bits (351), Expect = 2.246e-34
Identity = 92/283 (32.51%), Postives = 152/283 (53.71%), Query Frame = 1
Query:  424 EFYIGKEALEVPIEANYNLHWPFWDDKI----SDKYSKTAAVKDLEDIWRMGIEKSLKIPSEDLANYRIILVISDLIIRSEIRWIIEMLINELKFSNIVLQQENVCITYSTGLPTACVVNMHENSISISCVEEGISIPEGRIKLLYGTSDILCLFHSLLIRIGFP--KTAIESYSDYQGVQSIEELFATACELIPSNESKASKLNGNRKSI-DPNGRIRCQSIDMYIGSEAIIAGLALFHPSLICKDSPKY-QFQHNLADESEPDDPFDDLYLTLTSRDRKKQ 1248
            E+ +G+EAL V     YN+HWP    ++        S TA + D+E IW   I+K L+IP +DL  YR IL+I D+  +  ++ ++ M++ ++ FS IV+ QE+VC TY +GL + C+V++ +   S+ CVE+G+S    R+ L YG SD+   F+ L+ R GFP  +  + +  D   +Q ++E F   C L    +   S L  +   I  P+           +G E + A +ALF+P+       K    QH    + +P+DP D+ YL L ++ +++Q
Sbjct:   53 EYLVGEEALYVNPLDCYNIHWPIRRGQLNIHPGPGGSLTAVLADIEVIWSHAIQKYLEIPLKDLKYYRCILLIPDIYNKQHVKELVNMILMKMGFSGIVVHQESVCATYGSGLSSTCIVDVGDQKTSVCCVEDGVSHRNTRLCLAYGGSDVSRCFYWLMQRAGFPYRECQLTNKMDCLLLQHLKETF---CHL----DQDISGLQDHEFQIRHPDSPALL--YQFRLGDEKLQAPMALFYPATFGIVGQKMTTLQHR--SQGDPEDPHDEHYL-LATQSKQEQ 323          

HSP 2 Score: 53.1434 bits (126), Expect = 1.536e-6
Identity = 39/130 (30.00%), Postives = 64/130 (49.23%), Query Frame = 1
Query: 1486 NKALPLNDAIVKSINKSLSSLAVVIDNITETSQQLCSVILA-GEPIEFPGCVELLE----NSLKPSLSQCGE-VEVIHNDFTDGISAHSAAWKGASMITLVGYCDDLWISGKDWNKYGSRAIREKAPFLW 1857
             KAL L+ AI+ SI+   S          +T +++ S IL  G  + F    E L+    N + PS  +  E V+VI       +     AWKG +++  +    +LWI  ++W ++G R +RE+A F+W
Sbjct:  395 GKALGLDKAILHSIDCCSSD---------DTKKKMYSSILVVGGGLMFHKAQEFLQHRILNKMPPSFRRIIENVDVITR--PKDMDPRLIAWKGGAVLACLDTTQELWIYQREWQRFGVRMLRERAAFVW 513          
BLAST of Actin-related protein 8 vs. Ensembl Human
Match: ACTR8 (actin related protein 8 [Source:HGNC Symbol;Acc:HGNC:14672])

HSP 1 Score: 92.4337 bits (228), Expect = 2.197e-19
Identity = 41/103 (39.81%), Postives = 68/103 (66.02%), Query Frame = 1
Query:  529 AAVKDLEDIWRMGIEKSLKIPSEDLANYRIILVISDLIIRSEIRWIIEMLINELKFSNIVLQQENVCITYSTGLPTACVVNMHENSISISCVEEGISIPEGRI 837
            A + D+E IW   I+K L+IP +DL  YR IL+I D+  +  ++ ++ M++ ++ FS IV+ QE+VC TY +GL + C+V++ +   S+ CVE+G+S    RI
Sbjct:    2 AVLADIEVIWSHAIQKYLEIPLKDLKYYRCILLIPDIYNKQHVKELVNMILMKMGFSGIVVHQESVCATYGSGLSSTCIVDVGDQKTSVCCVEDGVSHRNTRI 104          

HSP 2 Score: 53.9138 bits (128), Expect = 7.214e-7
Identity = 39/130 (30.00%), Postives = 64/130 (49.23%), Query Frame = 1
Query: 1486 NKALPLNDAIVKSINKSLSSLAVVIDNITETSQQLCSVILA-GEPIEFPGCVELLE----NSLKPSLSQCGE-VEVIHNDFTDGISAHSAAWKGASMITLVGYCDDLWISGKDWNKYGSRAIREKAPFLW 1857
             KAL L+ AI+ SI+   S          +T +++ S IL  G  + F    E L+    N + PS  +  E V+VI       +     AWKG +++  +    +LWI  ++W ++G R +RE+A F+W
Sbjct:  260 GKALGLDKAILHSIDCCSSD---------DTKKKMYSSILVVGGGLMFHKAQEFLQHRILNKMPPSFRRIIENVDVITR--PKDMDPRLIAWKGGAVLACLDTTQELWIYQREWQRFGVRMLRERAAFVW 378          
BLAST of Actin-related protein 8 vs. Ensembl Fly
Match: Arp8 (gene:FBgn0030877 transcript:FBtr0074544)

HSP 1 Score: 177.948 bits (450), Expect = 5.827e-47
Identity = 169/623 (27.13%), Postives = 272/623 (43.66%), Query Frame = 1
Query:   85 IIVIHPSATKLRFGRSNDSEPIIIPHCIA--RKCKIISKVIRQPKIP--DN-RASTLLNTKFNNAIKLASIAMKSSSIEVLQPFKEQPTINELIHMNKQYLKXXXXXXXXXXHRVYSEEFYIGKEA----------LEVPIEANYNLHWPFWDDKISDKYSK----TAAVKDLEDIWRMGIEKSLKIPSEDLANYRIILVISDLIIRSEIRWIIEMLINELKFSNIVLQQENVCITYSTGLPTACVVNMHENSISISCVEEGISIPEGRIKLLYGTSDILCLFHSLLIRIGFPKTAIESYSDYQGVQSIEELFATACELIPSNESKASKLNGNRKSIDPNGRIRCQSIDMYIGSEAIIAGLALFHPSL--ICKDSPKYQFQHNLADESEPDDPFDDLYLTLTSRDRKKQRLDEXXXXXXXXXXXXXXXFQQAGDE----IDPDEDXXXXXXXXXXXXXXXXXXXXXXXXXXKLHRISNLIPESPG------SCSQNDPNKALPLNDAIVKSINKSLSSLAVVIDNITETSQQL-CSVILAGEPIEFPGCVELLENSLKPSLSQCGEVEVIHNDFTDGISAHSAAWKGASMITLVGYCDDLWISGKDWNKYGSRAIREKAPFLW 1857
            IIVIHP +  LR GR+ D  P+ + H +A  R+     +    P +P  DN  +++ L  +F     + S  ++   ++     +      +L H N+        +         ++E ++ +EA          L      NY++H+P    +++    K     A+++ LE IW   +E+ LKIP   L  +  +LV++D+ +R  +R  + +L+  L F    L Q++V  T+  G+   CVV++     SI+C+E+GIS  + R++L YG  D+  +   LL + GFP         Y     ++EL    C L  S      K    RK    NG+    +I   +G EA++A LALFH  L  I   +     Q  + D+ + +D FD  YL  T R    +  D                   A DE    +D DE   N                            S L  ++ G       C  N     LPL+ AI++SIN+ LSS         ET +++  S++L G   + PG    LE      +SQ  + EV  N    G+ A   AWKGA++++++    +LWIS  DW ++G R +RE++PFLW
Sbjct:   35 IIVIHPGSQHLRIGRAADLNPLTLLHAVAYRRRPGASDRPHHDPLLPPLDNVNSNSGLMVEFEEQRLVVSRILQHCVVDNKNRLRVATPPQQLAHFNRSSQAEKVPAPSGQ----MADEPWLDREAPVLFDDRILRLGAVDARNYDIHFPIQRGELNVHNEKGGSLQASMQHLERIWSYALEERLKIPLRKLGTHCAVLVVNDVYVRRHLREFVTLLLRRLGFRRCFLVQDSVASTFGAGIGYGCVVDIGAQKTSIACIEDGISQLDARVRLSYGGGDLDQVLLLLLRKCGFPYRECNVQESYVDAHLLDELKEKFCHLNASVCGAQEKHFNLRKH---NGQWLRYTIQ--VGDEALMAPLALFHTELLNITGRTKAVFTQQAVQDQYDCEDCFDAEYLKETGRKNGVRGGDILQLSTSAGYQPRPQLPVTADDEELIVVDQDETISNCQ--------------------------SQLGAQTAGGQMNSNGCYHNGQGLVLPLDQAIIQSINR-LSSY--------ETKRKMFGSILLVGSSAKLPGLAAWLEQ----RISQQVQSEV--NVLIKGMDAGMVAWKGAAIMSVLESARELWISQNDWQRHGLRVLRERSPFLW 607          
BLAST of Actin-related protein 8 vs. Ensembl Zebrafish
Match: actr8 (actin related protein 8 [Source:NCBI gene;Acc:326866])

HSP 1 Score: 159.844 bits (403), Expect = 1.239e-40
Identity = 119/405 (29.38%), Postives = 199/405 (49.14%), Query Frame = 1
Query:   85 IIVIHPSATKLRFGRSNDSEPIIIPHCIARKCKIISKVIRQPK--IPDNRASTLLNTKFNNAIKLASIAMKSSSIEVLQPFKEQPTINELIHMNKQYLKXXX---XXXXXXXHRVYSEEFYIGKEALEVPIEANYNLHWPFWDDKI----SDKYSKTAAVKDLEDIWRMGIEKSLKIPSEDLANYRIILVISDLIIRSEIRWIIEMLINELKFSNIVLQQENVCITYSTGLPTACVVNMHENSISISCVEEGISIPEGRIKLLYGTSDILCLFHSLLIRIGFPKTAIESYSDYQGVQSIEELFATACELIPSNESKASKLNGNRKSI-DPNGRIRCQS-----IDMYIGSEAIIAGLALFHPSLICKDSPKYQFQHNLADESEPD--DPFDDLYLTLTSRDRKKQ 1248
            I+VIHP +  LR GR+ D+ PI +PH IAR+ K   +   + K  + +   S   N +  N +K+    + S  +      +  P   E   +  + ++       S +S  +  +  E+ +G+EAL V     Y++HWP    ++        S +A + DLE IW   ++K L+IP +DL  YR IL+I D+  R  ++ I+ ML+ ++ FS +V+ QE+VC T+ +GL +ACVV++ +   S+ CVE+G+S    R+ L YG SD+   F  L+ R GFP      Y D Q    ++      C L+   +     L+ +   + D   R R          + +G E + A + LF+P+       K     +L   S+ D  DP D+ +L LT++ ++ Q
Sbjct:   48 IVVIHPGSRTLRLGRATDTLPISVPHVIARRHKHPGQSRYEDKCLLREGLNSADSNEQRQNGLKMVDQVIWSKKMS--NGVRRTPVSAEQARLYNRQIRPAVLDPNSKVSWTNTSHHPEYVVGEEALYVNPTDCYSVHWPVCRGRLNLHSGSGGSLSAVMMDLEHIWTHALQKLLQIPLKDLKYYRCILLIPDIYNRQHVKEIVNMLLVKMGFSAVVVHQESVCATFGSGLSSACVVDVGDQKTSVCCVEDGVSHRSSRLCLAYGGSDVTRCFFWLMQRAGFP------YRDCQLGNKLD------CVLLQQLKESFCHLDQDISGLQDHEFRTRFPDSPVLLYQLRLGDEKLQAPMTLFYPAAFGIVGQKMT---SLLHRSQGDAEDPHDEHFL-LTTQSKQDQ 434          

HSP 2 Score: 59.3066 bits (142), Expect = 1.600e-8
Identity = 41/130 (31.54%), Postives = 63/130 (48.46%), Query Frame = 1
Query: 1486 NKALPLNDAIVKSINKSLSSLAVVIDNITETSQQLCSVILA-GEPIEFPGCVELLE----NSLKPSLSQCGE-VEVIHNDFTDGISAHSAAWKGASMITLVGYCDDLWISGKDWNKYGSRAIREKAPFLW 1857
             KAL ++ AI+ SI+   S          ET +++ S IL  G  + F G  E L+    N + PS     E V+VI         A    WKG S++  +    +LWI  ++W ++G R +RE+A F+W
Sbjct:  505 GKALGIDKAILHSIDSCASD---------ETKRKMYSCILVVGGGLLFHGAQEFLQHRILNKMPPSFRCMVESVDVITR--PKDTDARVCVWKGGSVLACLDTTQELWIHQREWQRFGVRMLRERAAFVW 623          
BLAST of Actin-related protein 8 vs. Ensembl Xenopus
Match: edn1 (endothelin 1 [Source:Xenbase;Acc:XB-GENE-491328])

HSP 1 Score: 105.916 bits (263), Expect = 1.649e-25
Identity = 54/136 (39.71%), Postives = 84/136 (61.76%), Query Frame = 1
Query:  424 EFYIGKEALEVPIEANYNLHWPFWDDKI----SDKYSKTAAVKDLEDIWRMGIEKSLKIPSEDLANYRIILVISDLIIRSEIRWIIEMLINELKFSNIVLQQENVCITYSTGLPTACVVNMHENSISISCVEEGIS 819
            E+ +G+EAL V     YNLH+P    ++        S TA + DLE IW   ++K L+I  +DL  YR IL+I D+  R  ++ ++ ML+ ++ FS I++ QE+VC  Y +GL +ACVV++ +   S+ CVE+GIS
Sbjct:   53 EYLVGEEALYVNPSDCYNLHYPIRRGQLNLHSGPGGSLTAVLADLETIWSHVLQKMLEIQLKDLKYYRCILLIPDIYNRQHVKEMVNMLLMKMGFSGIIVHQESVCAMYGSGLSSACVVDVGDQKTSVCCVEDGIS 188          
BLAST of Actin-related protein 8 vs. Ensembl Mouse
Match: Actr8 (ARP8 actin-related protein 8 [Source:MGI Symbol;Acc:MGI:1860775])

HSP 1 Score: 183.726 bits (465), Expect = 1.143e-48
Identity = 173/628 (27.55%), Postives = 277/628 (44.11%), Query Frame = 1
Query:   85 IIVIHPSATKLRFGRSNDSEPIIIPHCIARKCKIISKVIRQPKIPDNRASTLLNTKFN---------NAIKLASIAMKSSSIEVLQPFKEQPTINELIH-MNKQYLKXXXXXXXXXXHRVYSE--EFYIGKEALEVPIEANYNLHWPFWDDKI----SDKYSKTAAVKDLEDIWRMGIEKSLKIPSEDLANYRIILVISDLIIRSEIRWIIEMLINELKFSNIVLQQENVCITYSTGLPTACVVNMHENSISISCVEEGISIPEGRIKLLYGTSDILCLFHSLLIRIGFP--KTAIESYSDYQGVQSIEELFATACELIPSNESKASKLNGNRKSI-DPNGRIRCQSIDMYIGSEAIIAGLALFHPSLICKDSPKY-QFQHNLADESEPDDPFDDLYLTLTSRDRKKQRLDEXXXXXXXXXXXXXXXFQQAGDEIDPDEDXXXXXXXXXXXXXXXXXXXXXXXXXXKLHRISNLIPESPGSC--SQNDPNKALPL----NDAIVKSINKSLSSLAVVIDNI-----TETSQQLCSVIL-AGEPIEFPGCVELLE----NSLKPSLSQCGE-VEVIHNDFTDGISAHSAAWKGASMITLVGYCDDLWISGKDWNKYGSRAIREKAPFLW 1857
            I+VIHP +T LR GR+ D+ P+ +PH IAR+     K   QP   DN    LL    N         N +K+   A+ S  +      +  P   E     NKQ           +     S+  E+ +G+EAL V     YN+HWP    ++        S TA + D+E IW   I+K L+IP +DL  YR IL+I D+  +  ++ ++ M++ ++ F+ IV+ QE+VC T+ +GL + CVV++ +   S+ CVE+G+S    R+ L YG SD+   F+ L+ R GFP  +  + +  D   +Q ++E F   C L    +   S L  +   I  P+           +G E + A +ALF+P+       K    QH    + +P+DP D+ YL  T      Q   E    A      ++      GD      D                          +LH     +  S G C  + N+  +AL        AI     K+L     ++ ++      +T +++ S IL  G  + F    E L+    N + PS  +  E V+VI       +     AWKG +++  +    +LWI  ++W ++G R +RE+A F+W
Sbjct:   48 IVVIHPGSTTLRLGRATDTLPVSVPHVIARR----HKQQGQPLYKDN---WLLREGLNKPESNEQRQNGLKMVDQAIWSKKMS--NGTRRIPVSPEQTRSYNKQMRPAILDHCSGNKWTNTSQQPEYLVGEEALYVNPLDCYNIHWPIRRGQLNIHPGPGGSLTAVLADIEVIWSHAIQKYLEIPLKDLKYYRCILLIPDIYNKQHVKELVHMILMKMGFAGIVVHQESVCATFGSGLSSTCVVDVGDQKTSVCCVEDGVSHRNTRLCLAYGGSDVSRCFYWLMQRAGFPYRECQLTNKMDCLLLQHLKETF---CHL----DQDISGLQDHEFQIRHPDSPALL--YQFRLGDEKLQAPMALFYPATFGIVGQKMTTLQHR--SQGDPEDPHDEHYLLAT------QSKQEQSAKATADRKSASKPIGFEGDLRGQSSD-----------------------LPERLHSQEVDLASSQGDCLMAGNESEEALTALMSRKTAISLFEGKALGLDKAILHSVDCCSSDDTKKKMYSSILVVGGGLMFHKAQEFLQHRILNKMPPSFRRIIENVDVITR--PKDMDPRLIAWKGGAVLACLDTTQELWIYQREWQRFGVRMLRERAAFVW 624          
BLAST of Actin-related protein 8 vs. Ensembl Mouse
Match: Actr8 (ARP8 actin-related protein 8 [Source:MGI Symbol;Acc:MGI:1860775])

HSP 1 Score: 183.726 bits (465), Expect = 1.143e-48
Identity = 173/628 (27.55%), Postives = 277/628 (44.11%), Query Frame = 1
Query:   85 IIVIHPSATKLRFGRSNDSEPIIIPHCIARKCKIISKVIRQPKIPDNRASTLLNTKFN---------NAIKLASIAMKSSSIEVLQPFKEQPTINELIH-MNKQYLKXXXXXXXXXXHRVYSE--EFYIGKEALEVPIEANYNLHWPFWDDKI----SDKYSKTAAVKDLEDIWRMGIEKSLKIPSEDLANYRIILVISDLIIRSEIRWIIEMLINELKFSNIVLQQENVCITYSTGLPTACVVNMHENSISISCVEEGISIPEGRIKLLYGTSDILCLFHSLLIRIGFP--KTAIESYSDYQGVQSIEELFATACELIPSNESKASKLNGNRKSI-DPNGRIRCQSIDMYIGSEAIIAGLALFHPSLICKDSPKY-QFQHNLADESEPDDPFDDLYLTLTSRDRKKQRLDEXXXXXXXXXXXXXXXFQQAGDEIDPDEDXXXXXXXXXXXXXXXXXXXXXXXXXXKLHRISNLIPESPGSC--SQNDPNKALPL----NDAIVKSINKSLSSLAVVIDNI-----TETSQQLCSVIL-AGEPIEFPGCVELLE----NSLKPSLSQCGE-VEVIHNDFTDGISAHSAAWKGASMITLVGYCDDLWISGKDWNKYGSRAIREKAPFLW 1857
            I+VIHP +T LR GR+ D+ P+ +PH IAR+     K   QP   DN    LL    N         N +K+   A+ S  +      +  P   E     NKQ           +     S+  E+ +G+EAL V     YN+HWP    ++        S TA + D+E IW   I+K L+IP +DL  YR IL+I D+  +  ++ ++ M++ ++ F+ IV+ QE+VC T+ +GL + CVV++ +   S+ CVE+G+S    R+ L YG SD+   F+ L+ R GFP  +  + +  D   +Q ++E F   C L    +   S L  +   I  P+           +G E + A +ALF+P+       K    QH    + +P+DP D+ YL  T      Q   E    A      ++      GD      D                          +LH     +  S G C  + N+  +AL        AI     K+L     ++ ++      +T +++ S IL  G  + F    E L+    N + PS  +  E V+VI       +     AWKG +++  +    +LWI  ++W ++G R +RE+A F+W
Sbjct:   48 IVVIHPGSTTLRLGRATDTLPVSVPHVIARR----HKQQGQPLYKDN---WLLREGLNKPESNEQRQNGLKMVDQAIWSKKMS--NGTRRIPVSPEQTRSYNKQMRPAILDHCSGNKWTNTSQQPEYLVGEEALYVNPLDCYNIHWPIRRGQLNIHPGPGGSLTAVLADIEVIWSHAIQKYLEIPLKDLKYYRCILLIPDIYNKQHVKELVHMILMKMGFAGIVVHQESVCATFGSGLSSTCVVDVGDQKTSVCCVEDGVSHRNTRLCLAYGGSDVSRCFYWLMQRAGFPYRECQLTNKMDCLLLQHLKETF---CHL----DQDISGLQDHEFQIRHPDSPALL--YQFRLGDEKLQAPMALFYPATFGIVGQKMTTLQHR--SQGDPEDPHDEHYLLAT------QSKQEQSAKATADRKSASKPIGFEGDLRGQSSD-----------------------LPERLHSQEVDLASSQGDCLMAGNESEEALTALMSRKTAISLFEGKALGLDKAILHSVDCCSSDDTKKKMYSSILVVGGGLMFHKAQEFLQHRILNKMPPSFRRIIENVDVITR--PKDMDPRLIAWKGGAVLACLDTTQELWIYQREWQRFGVRMLRERAAFVW 624          
BLAST of Actin-related protein 8 vs. UniProt/SwissProt
Match: sp|Q1LZF2|ARP8_BOVIN (Actin-related protein 8 OS=Bos taurus OX=9913 GN=ACTR8 PE=2 SV=1)

HSP 1 Score: 187.193 bits (474), Expect = 5.287e-49
Identity = 176/638 (27.59%), Postives = 279/638 (43.73%), Query Frame = 1
Query:   85 IIVIHPSATKLRFGRSNDSEPIIIPHCIARKCKIISKVIRQPKIPDNRASTLLNTKFN---------NAIKLASIAMKSSSI-----------EVLQPFKEQ--PTINELIHMNKQYLKXXXXXXXXXXHRVYSEEFYIGKEALEVPIEANYNLHWPFWDDKI----SDKYSKTAAVKDLEDIWRMGIEKSLKIPSEDLANYRIILVISDLIIRSEIRWIIEMLINELKFSNIVLQQENVCITYSTGLPTACVVNMHENSISISCVEEGISIPEGRIKLLYGTSDILCLFHSLLIRIGFP--KTAIESYSDYQGVQSIEELFATACELIPSNESKASKLNGNRKSI-DPNGRIRCQSIDMYIGSEAIIAGLALFHPSLICKDSPKY-QFQHNLADESEPDDPFDDLYLTLTSRDRKKQRLDEXXXXXXXXXXXXXXXFQQAGDEIDPDEDXXXXXXXXXXXXXXXXXXXXXXXXXXKLHRISNLIPESPGSC--SQNDPNKALPL----NDAIVKSINKSLSSLAVVIDNI-----TETSQQLCSVIL-AGEPIEFPGCVELLE----NSLKPSLSQCGE-VEVIHNDFTDGISAHSAAWKGASMITLVGYCDDLWISGKDWNKYGSRAIREKAPFLW 1857
            I+VIHP +T LR GR+ D+ P  +PH IAR+ K       Q   P  + S LL    N         N +K+   A+ S  +           E  + + +Q  P I +    NK              +  +  EF +G+EAL V     YN+HWP    ++        S TA + D+E IW   I+K L+IP +DL  YR IL+I D+  +  ++ ++ M++ ++ FS IV+ QE+VC T+ +GL + C+V++ +   S+ CVE+G+S    R+ L YG SD+   F+ L+ R GFP  +  + +  D   +Q ++E F   C L    +   S L  +   I  P+           +G E + A +ALF+P+       K    QH    + +P+DP D+ YL  T      Q   E    A      ++      GD      D                          +LH     +  S G C  + ND  +AL        AI     K+L     ++ +I      ET +++ S IL  G  + F    E L+    N + PS  +  E V+VI       +     AWKG +++  +    +LWI  ++W ++G R +RE+A F+W
Sbjct:   48 IVVIHPGSTTLRIGRATDTLPASVPHVIARRHK-------QQGQPLYKDSWLLREGLNKPESNEQRQNGLKMVDQAIWSKKMSNGTRRIPVSPEQARSYNKQMRPAILDHCSGNK------------WTNTSHHPEFLVGEEALYVNPLDCYNIHWPIRRGQLNIHPGPGGSLTAVLADIEVIWSHAIQKYLEIPLKDLKYYRCILLIPDIYNKQHVKELVNMILMKMGFSGIVVHQESVCATFGSGLSSTCIVDVGDQKTSVCCVEDGVSHRNTRLCLAYGGSDVSRCFYWLMQRAGFPYRECQLTNKMDCLLLQHLKETF---CHL----DQDISGLQDHEFQIRHPDSPALL--YQFRLGDEKLQAPMALFYPATFGIVGQKMTTLQHR--SQGDPEDPHDEQYLLAT------QSKQEQSAKATADRKSASKPIGFEGDLRGQSSD-----------------------LPERLHSQEVDLGPSQGDCLMAGNDSEEALTALMSRKTAISLFEGKALGLDKAILHSIDCCSSDETKKKMYSSILVVGGGLMFHKAQEFLQHRILNKMPPSFRRIIENVDVITR--PKDMDPRLIAWKGGAVLACLDTTQELWIYQREWQRFGVRMLRERAAFVW 624          
BLAST of Actin-related protein 8 vs. UniProt/SwissProt
Match: sp|D2I1E3|ARP8_AILME (Actin-related protein 8 OS=Ailuropoda melanoleuca OX=9646 GN=ACTR8 PE=3 SV=1)

HSP 1 Score: 184.111 bits (466), Expect = 5.509e-48
Identity = 176/638 (27.59%), Postives = 279/638 (43.73%), Query Frame = 1
Query:   85 IIVIHPSATKLRFGRSNDSEPIIIPHCIARKCKIISKVIRQPKIPDNRASTLLNTKFN---------NAIKLASIAMKSSSI-----------EVLQPFKEQ--PTINELIHMNKQYLKXXXXXXXXXXHRVYSEEFYIGKEALEVPIEANYNLHWPFWDDKI----SDKYSKTAAVKDLEDIWRMGIEKSLKIPSEDLANYRIILVISDLIIRSEIRWIIEMLINELKFSNIVLQQENVCITYSTGLPTACVVNMHENSISISCVEEGISIPEGRIKLLYGTSDILCLFHSLLIRIGFP--KTAIESYSDYQGVQSIEELFATACELIPSNESKASKLNGNRKSI-DPNGRIRCQSIDMYIGSEAIIAGLALFHPSLICKDSPKY-QFQHNLADESEPDDPFDDLYLTLTSRDRKKQRLDEXXXXXXXXXXXXXXXFQQAGDEIDPDEDXXXXXXXXXXXXXXXXXXXXXXXXXXKLHRISNLIPESPGSC--SQNDPNKALPL----NDAIVKSINKSLSSLAVVIDNI-----TETSQQLCSVIL-AGEPIEFPGCVELLE----NSLKPSLSQCGE-VEVIHNDFTDGISAHSAAWKGASMITLVGYCDDLWISGKDWNKYGSRAIREKAPFLW 1857
            I+VIHP +T LR GR+ D+ P  IPH IAR+     K   QP   DN    LL    N         N +K+   A+ S  +           E  + + +Q  P I +    NK              +  +  EF +G+EAL V     YN+HWP    ++        S TA + D+E IW   I+K L+IP +DL  YR IL+I D+  +  ++ ++ M++ ++ FS IV+ QE+VC T+ +GL + C+V++ +   S+ CVE+G+S    R+ L YG SD+   F+ L+ R GFP  +  + +  D   +Q ++E F   C L    +   S L  +   I  P+           +G E + A +ALF+P+       K    QH    + +P+DP D+ YL  T      Q   E    A      ++      GD      D                          +LH     +  S G C  + N+  +AL        AI     K+L     ++ +I      +T +++ S IL  G  + F    E L+    N + PS  +  E V+VI       +     AWKG +++  +    +LWI  ++W ++G R +RE+A F+W
Sbjct:   48 IVVIHPGSTTLRIGRATDTLPASIPHVIARR----HKQQGQPLYKDN---WLLREGLNKPESNEQRQNGLKMVDQAIWSKKMSNGTRRIPVSPEQARSYNKQMRPAILDHCSGNK------------WTNTSHHPEFLVGEEALYVNPLDCYNIHWPIRRGQLNIHPGPGGSLTAVLADIEVIWSHAIQKYLEIPLKDLKYYRCILLIPDIYNKQHVKELVNMILMKMGFSGIVVHQESVCATFGSGLSSTCIVDVGDQKTSVCCVEDGVSHRNTRLCLAYGGSDVSRCFYWLMQRAGFPYRECQLTNKMDCLLLQHLKETF---CHL----DQDISGLQDHEFQIRHPDSPALL--YQFRLGDEKLQAPMALFYPATFGIVGQKMTTLQHR--SQGDPEDPHDEHYLLAT------QSKQEQSAKATADRKSASKPIGFEGDLRGQSSD-----------------------LPERLHAQEVDLGSSQGDCLMAGNESEEALTALMSRKTAISLFEGKALGLDKAILHSIDCCSSDDTKKKMYSSILVVGGGLMFHKAQEFLQHRILNKMPPSFRRIIENVDVITR--PKDMDPRLIAWKGGAVLACLDTTQELWIYQREWQRFGVRMLRERAAFVW 624          
BLAST of Actin-related protein 8 vs. UniProt/SwissProt
Match: sp|Q8R2S9|ARP8_MOUSE (Actin-related protein 8 OS=Mus musculus OX=10090 GN=Actr8 PE=2 SV=1)

HSP 1 Score: 183.726 bits (465), Expect = 7.993e-48
Identity = 173/628 (27.55%), Postives = 277/628 (44.11%), Query Frame = 1
Query:   85 IIVIHPSATKLRFGRSNDSEPIIIPHCIARKCKIISKVIRQPKIPDNRASTLLNTKFN---------NAIKLASIAMKSSSIEVLQPFKEQPTINELIH-MNKQYLKXXXXXXXXXXHRVYSE--EFYIGKEALEVPIEANYNLHWPFWDDKI----SDKYSKTAAVKDLEDIWRMGIEKSLKIPSEDLANYRIILVISDLIIRSEIRWIIEMLINELKFSNIVLQQENVCITYSTGLPTACVVNMHENSISISCVEEGISIPEGRIKLLYGTSDILCLFHSLLIRIGFP--KTAIESYSDYQGVQSIEELFATACELIPSNESKASKLNGNRKSI-DPNGRIRCQSIDMYIGSEAIIAGLALFHPSLICKDSPKY-QFQHNLADESEPDDPFDDLYLTLTSRDRKKQRLDEXXXXXXXXXXXXXXXFQQAGDEIDPDEDXXXXXXXXXXXXXXXXXXXXXXXXXXKLHRISNLIPESPGSC--SQNDPNKALPL----NDAIVKSINKSLSSLAVVIDNI-----TETSQQLCSVIL-AGEPIEFPGCVELLE----NSLKPSLSQCGE-VEVIHNDFTDGISAHSAAWKGASMITLVGYCDDLWISGKDWNKYGSRAIREKAPFLW 1857
            I+VIHP +T LR GR+ D+ P+ +PH IAR+     K   QP   DN    LL    N         N +K+   A+ S  +      +  P   E     NKQ           +     S+  E+ +G+EAL V     YN+HWP    ++        S TA + D+E IW   I+K L+IP +DL  YR IL+I D+  +  ++ ++ M++ ++ F+ IV+ QE+VC T+ +GL + CVV++ +   S+ CVE+G+S    R+ L YG SD+   F+ L+ R GFP  +  + +  D   +Q ++E F   C L    +   S L  +   I  P+           +G E + A +ALF+P+       K    QH    + +P+DP D+ YL  T      Q   E    A      ++      GD      D                          +LH     +  S G C  + N+  +AL        AI     K+L     ++ ++      +T +++ S IL  G  + F    E L+    N + PS  +  E V+VI       +     AWKG +++  +    +LWI  ++W ++G R +RE+A F+W
Sbjct:   48 IVVIHPGSTTLRLGRATDTLPVSVPHVIARR----HKQQGQPLYKDN---WLLREGLNKPESNEQRQNGLKMVDQAIWSKKMS--NGTRRIPVSPEQTRSYNKQMRPAILDHCSGNKWTNTSQQPEYLVGEEALYVNPLDCYNIHWPIRRGQLNIHPGPGGSLTAVLADIEVIWSHAIQKYLEIPLKDLKYYRCILLIPDIYNKQHVKELVHMILMKMGFAGIVVHQESVCATFGSGLSSTCVVDVGDQKTSVCCVEDGVSHRNTRLCLAYGGSDVSRCFYWLMQRAGFPYRECQLTNKMDCLLLQHLKETF---CHL----DQDISGLQDHEFQIRHPDSPALL--YQFRLGDEKLQAPMALFYPATFGIVGQKMTTLQHR--SQGDPEDPHDEHYLLAT------QSKQEQSAKATADRKSASKPIGFEGDLRGQSSD-----------------------LPERLHSQEVDLASSQGDCLMAGNESEEALTALMSRKTAISLFEGKALGLDKAILHSVDCCSSDDTKKKMYSSILVVGGGLMFHKAQEFLQHRILNKMPPSFRRIIENVDVITR--PKDMDPRLIAWKGGAVLACLDTTQELWIYQREWQRFGVRMLRERAAFVW 624          
BLAST of Actin-related protein 8 vs. UniProt/SwissProt
Match: sp|Q29G73|ARP8_DROPS (Actin-related protein 8 OS=Drosophila pseudoobscura pseudoobscura OX=46245 GN=Arp8 PE=3 SV=2)

HSP 1 Score: 182.57 bits (462), Expect = 1.761e-47
Identity = 157/619 (25.36%), Postives = 277/619 (44.75%), Query Frame = 1
Query:   85 IIVIHPSATKLRFGRSNDSEPIIIPHCIA--RKCKIISKVIRQPKIP--DNRASTLLNTKFNNAIKLASIAMKSSSIEVLQPFKEQPTINELIHMNKQYLKXXXXXXXXXXHRVYSEEFYIGKEA----------LEVPIEANYNLHWPFWDDKISDKYSKTAAVK----DLEDIWRMGIEKSLKIPSEDLANYRIILVISDLIIRSEIRWIIEMLINELKFSNIVLQQENVCITYSTGLPTACVVNMHENSISISCVEEGISIPEGRIKLLYGTSDILCLFHSLLIRIGFPK---TAIESYSDYQGVQSIEELFATACELIPSNESKASKLNGNRKSIDPNGRIRCQSIDMYIGSEAIIAGLALFHPSL--ICKDSPKYQFQHNLADESEPDDPFDDLYLTLTSRDRKKQRLDEXXXXXXXXXXXXXXXFQQAGDE----IDPDEDXXXXXXXXXXXXXXXXXXXXXXXXXXKLHRISNLIPESPGSCSQNDPNKALPLNDAIVKSINKSLSSLAVVIDNITETSQQL-CSVILAGEPIEFPGCVELLENSLKPSLSQCGEVEVIHNDFTDGISAHSAAWKGASMITLVGYCDDLWISGKDWNKYGSRAIREKAPFLW 1857
            IIVIHP +  LR GR+ D  P+ + H +A  RK +        P +P  DN     L  +F     +AS  +++  I+  Q  +      +L H N++ +        +       +  ++ ++A          L      +Y++H+P    +++    K  +++     +E IW   +E  LKI   DL  +  +LV++D+ +R  +R  + +L+  L F    L Q++V  TY  G+   CVV++     SI+C+E+GIS    R++L YG  DI  +   LL + GFP    +  +SY D + +  ++E F      +   + K   L   RK    NG  +     + +G EAI+A LA FH  L  I   + K   Q    ++ + +D FD  YL  T R    +  D                   A DE    +D DE              S +     N+++  +        ++     Q    + +PL+ A++++I +  ++         ET +++  S++L G  ++ PG    L++ +   +    EV V    FT G+ A   AWKGA++++++    +LWI+  DW+++G R +RE++PFLW
Sbjct:   28 IIVIHPGSQHLRIGRACDLNPLTMLHAVAYKRKHQEGDWPYHDPMLPSLDNINPAQLQVEFEEQRLIASRILQNCVIDDKQRLRVATPPQQLAHFNRKSVAEKIPPPGNLSEERNRQ--WLDRDAPVLFDEQILRLSTFDARDYDIHFPIQRGELNVHKQKGGSLQCTLQHIERIWSYALEARLKINLRDLRTHSAVLVVNDVYVRRHLREFMTLLLQRLGFQRCFLVQDSVASTYGAGIGFGCVVDIGAQKTSIACIEDGISQLNSRVRLQYGGGDINQVLLMLLRKCGFPYRECSVQDSYVDARLMDKLKERFCHLNAKVCGAQEKQFHL---RKQ---NG--QWLRYTLQVGDEAIMAPLAFFHTELLNITGKARKAFTQQPPQEQYDCEDCFDAEYLRETGRKNGARAADPIVAQLLAQPRPLPPI--TADDEELNVVDQDE-------------PSSNGVAVHNTSSPSVGHAQKHFADTANGVYQYGQGQVMPLDQAVLEAIGRCATN---------ETKRKMYGSILLVGSSVKIPGLAAWLQSCISQQVQPGTEVNV----FTKGMDAGMVAWKGAAIMSVLESARELWITQVDWSRHGLRLLRERSPFLW 608          
BLAST of Actin-related protein 8 vs. UniProt/SwissProt
Match: sp|Q9VX09|ARP8_DROME (Actin-related protein 8 OS=Drosophila melanogaster OX=7227 GN=Arp8 PE=1 SV=1)

HSP 1 Score: 177.948 bits (450), Expect = 5.841e-46
Identity = 169/623 (27.13%), Postives = 272/623 (43.66%), Query Frame = 1
Query:   85 IIVIHPSATKLRFGRSNDSEPIIIPHCIA--RKCKIISKVIRQPKIP--DN-RASTLLNTKFNNAIKLASIAMKSSSIEVLQPFKEQPTINELIHMNKQYLKXXXXXXXXXXHRVYSEEFYIGKEA----------LEVPIEANYNLHWPFWDDKISDKYSK----TAAVKDLEDIWRMGIEKSLKIPSEDLANYRIILVISDLIIRSEIRWIIEMLINELKFSNIVLQQENVCITYSTGLPTACVVNMHENSISISCVEEGISIPEGRIKLLYGTSDILCLFHSLLIRIGFPKTAIESYSDYQGVQSIEELFATACELIPSNESKASKLNGNRKSIDPNGRIRCQSIDMYIGSEAIIAGLALFHPSL--ICKDSPKYQFQHNLADESEPDDPFDDLYLTLTSRDRKKQRLDEXXXXXXXXXXXXXXXFQQAGDE----IDPDEDXXXXXXXXXXXXXXXXXXXXXXXXXXKLHRISNLIPESPG------SCSQNDPNKALPLNDAIVKSINKSLSSLAVVIDNITETSQQL-CSVILAGEPIEFPGCVELLENSLKPSLSQCGEVEVIHNDFTDGISAHSAAWKGASMITLVGYCDDLWISGKDWNKYGSRAIREKAPFLW 1857
            IIVIHP +  LR GR+ D  P+ + H +A  R+     +    P +P  DN  +++ L  +F     + S  ++   ++     +      +L H N+        +         ++E ++ +EA          L      NY++H+P    +++    K     A+++ LE IW   +E+ LKIP   L  +  +LV++D+ +R  +R  + +L+  L F    L Q++V  T+  G+   CVV++     SI+C+E+GIS  + R++L YG  D+  +   LL + GFP         Y     ++EL    C L  S      K    RK    NG+    +I   +G EA++A LALFH  L  I   +     Q  + D+ + +D FD  YL  T R    +  D                   A DE    +D DE   N                            S L  ++ G       C  N     LPL+ AI++SIN+ LSS         ET +++  S++L G   + PG    LE      +SQ  + EV  N    G+ A   AWKGA++++++    +LWIS  DW ++G R +RE++PFLW
Sbjct:   35 IIVIHPGSQHLRIGRAADLNPLTLLHAVAYRRRPGASDRPHHDPLLPPLDNVNSNSGLMVEFEEQRLVVSRILQHCVVDNKNRLRVATPPQQLAHFNRSSQAEKVPAPSGQ----MADEPWLDREAPVLFDDRILRLGAVDARNYDIHFPIQRGELNVHNEKGGSLQASMQHLERIWSYALEERLKIPLRKLGTHCAVLVVNDVYVRRHLREFVTLLLRRLGFRRCFLVQDSVASTFGAGIGYGCVVDIGAQKTSIACIEDGISQLDARVRLSYGGGDLDQVLLLLLRKCGFPYRECNVQESYVDAHLLDELKEKFCHLNASVCGAQEKHFNLRKH---NGQWLRYTIQ--VGDEALMAPLALFHTELLNITGRTKAVFTQQAVQDQYDCEDCFDAEYLKETGRKNGVRGGDILQLSTSAGYQPRPQLPVTADDEELIVVDQDETISNCQ--------------------------SQLGAQTAGGQMNSNGCYHNGQGLVLPLDQAIIQSINR-LSSY--------ETKRKMFGSILLVGSSAKLPGLAAWLEQ----RISQQVQSEV--NVLIKGMDAGMVAWKGAAIMSVLESARELWISQNDWQRHGLRVLRERSPFLW 607          
BLAST of Actin-related protein 8 vs. TrEMBL
Match: A0A4W4DUC2 (Actin-related protein 8 OS=Electrophorus electricus OX=8005 PE=3 SV=1)

HSP 1 Score: 206.838 bits (525), Expect = 2.491e-53
Identity = 176/628 (28.03%), Postives = 294/628 (46.82%), Query Frame = 1
Query:   85 IIVIHPSATKLRFGRSNDSEPIIIPHCIARKCKIISKVIRQPKIPDNRASTLLNTKFN---------NAIKLASIAMKSSSIEVLQPFKEQPTINELIHMNKQYLKXXX---XXXXXXXHRVYSEEFYIGKEALEVPIEANYNLHWPFWDDKIS----DKYSKTAAVKDLEDIWRMGIEKSLKIPSEDLANYRIILVISDLIIRSEIRWIIEMLINELKFSNIVLQQENVCITYSTGLPTACVVNMHENSISISCVEEGISIPEGRIKLLYGTSDILCLFHSLLIRIGFP--KTAIESYSDYQGVQSIEELFATACELIPSNESKASKLNGNRKSIDPNG------RIRCQSIDMY-----IGSEAIIAGLALFHPSLICKDSPKY-QFQHNLADESEPDDPFDDLYLTLT-SRDRKKQRLDEXXXXXXXXXXXXXXXFQQAGDEIDPDEDXXXXXXXXXXXXXXXXXXXXXXXXXXKLHRISNLIPESPGSCSQNDPNKALPLNDAIVKSINKSLSSLAVVIDNITETSQQLCSVIL-AGEPIEFPGCVELLE----NSLKPSLSQCGE-VEVIHNDFTDGISAHSAAWKGASMITLVGYCDDLWISGKDWNKYGSRAIREKAPFLW 1857
            I+VI+P +  LR GR+ D+ PI +PH I+R+ K       QP         LL    N         N +K+   A+ S  +      +  P   E   +  + ++       S +   H  +  E+ +G+EAL V    +Y++HWP    +++       S TA ++DLE IW   I+K L+IP +DL  YR IL+I D+  R  ++ ++ M++ ++ FS IV+ QE+VC T+ +GL +ACVV++ +   S+ CVE+G+S    R+ L YG SD+   F  L+ R GFP  +  + S  D   +Q ++E F   C L         ++   ++ +D  G      R R     ++     +G E + A +ALF+P+       K    QH      +P+DP D+ YL  T S+  +  +  E   ++  +G     +  Q GD+++                     ++  ++ +  L R S        + SQ +  KAL L+ AI+ SI+   S          ET +++ S IL  G  + F G  E L+    N + PS  +  E VEVI       +     AWKG +++  +    +LWI  ++W ++G+R +RE+A F+W
Sbjct:   51 IVVINPGSQTLRIGRATDTLPISVPHVISRRHK-------QPGQSRYEDPWLLREGLNRPESNEQRQNGLKMVDQAIWSKKMS--SGARRTPVSAEQARVYNRQIRPAILDPNSRLKWTHTAHQPEYLVGEEALNVNPTDSYSIHWPICRGQLNVHSRPGGSLTAILEDLETIWSHAIQKLLEIPLKDLKYYRCILLIPDIYNRQHVKEVVNMVLLKMGFSAIVVHQESVCATFGSGLSSACVVDVGDQKTSLCCVEDGVSHRNSRLCLAYGGSDVTRFFFWLMQRAGFPYRECQLTSRLDCMLLQQLKETF---CHL--------DQVWACQRVLDICGLQDHEFRTRFPECPVFLYQLRLGDEKLQAPMALFYPAAFGIVGQKMTTLQHR--SHGDPEDPHDEHYLLSTQSKQDQSSKATERKNLSKPSGFEGESSSSQGGDQVERGNHGQEVELGHAPGECLVGGADPEDTPSVLLSRKS--------AVSQFE-GKALGLDKAILHSIDCCASD---------ETKRKMYSSILVVGGGLLFHGAQEFLQQRLLNKMPPSFRRLVENVEVITR--PKDMDPQVTAWKGGAVLACLDTTQELWIHQREWQRFGARMLRERAAFVW 636          
BLAST of Actin-related protein 8 vs. TrEMBL
Match: A0A3B4BZE1 (Actin-related protein 8 OS=Pygocentrus nattereri OX=42514 PE=3 SV=1)

HSP 1 Score: 200.675 bits (509), Expect = 3.059e-51
Identity = 165/620 (26.61%), Postives = 286/620 (46.13%), Query Frame = 1
Query:   85 IIVIHPSATKLRFGRSNDSEPIIIPHCIARKCKIIS-------KVIRQP-KIPDNRASTLLNTKFNNAIKLASIAMKSSSIEVLQPFKEQPTINELIHMNKQYLKXXX---XXXXXXXHRVYSEEFYIGKEALEVPIEANYNLHWPFWDDKI----SDKYSKTAAVKDLEDIWRMGIEKSLKIPSEDLANYRIILVISDLIIRSEIRWIIEMLINELKFSNIVLQQENVCITYSTGLPTACVVNMHENSISISCVEEGISIPEGRIKLLYGTSDILCLFHSLLIRIGFP--KTAIESYSDYQGVQSIEELFATACELIPSNESKASKLNGNRKSIDPNGRIRCQSIDMYIGSEAIIAGLALFHPSLICKDSPKY-QFQHNLADESEPDDPFDDLYLTLTSRDRKKQRLDEXXXXXXXXXXXXXXXFQQAGDEIDPDEDXXXXXXXXXXXXXXXXXXXXXXXXXXKLHRISNLIPESPGSCSQNDPNKALPLNDAIVKSINKSLSSLAVVIDNI-----TETSQQLCSVIL-AGEPIEFPGCVELLE----NSLKPSLSQCGE-VEVIHNDFTDGISAHSAAWKGASMITLVGYCDDLWISGKDWNKYGSRAIREKAPFLW 1857
            ++VIHP +  LR GR+ D+ P+ +PH IAR+ K+ S       ++IR+    PD+        +  N +K+   A+ S  +      +  P   E   +  + ++       S +   +  +  E+ +G EAL V     Y++HWP    ++        S +A + D+E IW   I+K L+IP +DL  YR IL++ D+  R  ++ ++ ML+ ++ FS IV+ QE+VC T+ +GL +ACVV++ +   S+ CVE+G+S    R+ L YG SD+   F  L+ R GFP  +  + +  D   +Q ++E F   C L   ++      +   +S  P+  +      + +G E + A +ALF+P+       K    QH    + +P+DP D+ YL  T   + +              G    +  Q G   DP E   +                         H  ++ +    G+  +  P+  L    A+ +   K+L     V+ +I      ET +++ S IL  G  + F G  E L+    N + PS  +  E VEVI       +     AWKG +++  +    +LWI  ++W+++G+R +RE+A F+W
Sbjct:   51 VVVIHPGSQSLRIGRATDTLPVTVPHVIARRHKLPSQSRYEDPRLIREGLNRPDS------GEQRQNGLKMVDQAIWSKKMS--NGARRTPVSAEQARVYNRQIRPAVLDPNSRLKWTNTTHQPEYLVGDEALHVNPTDCYSIHWPICRGQLNVHTGPGGSLSAVLADVETIWSHAIQKLLEIPLKDLKYYRCILLVPDIYNRQHVKEVVNMLLVKMGFSAIVVHQESVCATFGSGLSSACVVDVGDQKTSVCCVEDGVSHRNSRLCLAYGGSDVTRCFFWLMQRAGFPYRECQLTNRLDCMLLQQLKETF---CHL---DQDICGMQDHEFRSRFPDSPVLL--YQLRLGDEKLQAPMALFYPAAFGIVGQKMTTLQHR--SQGDPEDPHDEHYLLSTQSKQDQSSRAMERKGLPKPPGFEGESSSQGG---DPSERGSHAQEELG-------------------HSQADCL--VGGTDPEETPSVLLSRKSAVTQFEGKALGLDKAVLHSIDCCASDETKRKMYSSILVVGGGLLFHGAQEFLQHRILNKMPPSFRRLVENVEVITR--PKDMDPRLTAWKGGAVLACLDTTQELWIHQREWHRFGARMLRERAAFVW 626          
BLAST of Actin-related protein 8 vs. TrEMBL
Match: A0A3B3QV60 (Actin-related protein 8 OS=Paramormyrops kingsleyae OX=1676925 PE=3 SV=1)

HSP 1 Score: 199.134 bits (505), Expect = 9.388e-51
Identity = 177/636 (27.83%), Postives = 288/636 (45.28%), Query Frame = 1
Query:   85 IIVIHPSATKLRFGRSNDSEPIIIPHCIARKCKIISKVIRQPKIPD--------NRASTLLNTKFNNAIKLASIAMKSSSIEVLQPFKEQPTINELIHMNKQYLKXXXXXXXXXXHRV------YSEEFYIGKEALEVPIEANYNLHWPFWDDKI----SDKYSKTAAVKDLEDIWRMGIEKSLKIPSEDLANYRIILVISDLIIRSEIRWIIEMLINELKFSNIVLQQENVCITYSTGLPTACVVNMHENSISISCVEEGISIPEGRIKLLYGTSDILCLFHSLLIRIGFP--KTAIESYSDYQGVQSIEELFATACELIPSNESKASKLNGNRKSIDPNGRIRCQS-----IDMYIGSEAIIAGLALFHPSLICKDSPKY-QFQHNLADESEPDDPFDDLYL--TLTSRDRKKQRLDEXXXXXXXXXXXXXXXFQQAGDEIDPDEDXXXXXXXXXXXXXXXXXXXXXXXXXXKLHRISNLIPESPGSC------SQNDPNKALPLNDAIVKSINKSLS---SLAVVIDNIT--ETSQQLCSVIL-AGEPIEFPGCVELLE----NSLKPSLSQCGE-VEVIHNDFTDGISAHSAAWKGASMITLVGYCDDLWISGKDWNKYGSRAIREKAPFLW 1857
            I+VI+P +  LR GR+ D+ P ++PH IAR+ K  S    QP+  D        NR  +  N +  N +K+   A+ S  +      +  P   E     + Y +    + + S  RV      +  EF IG+EAL V    +Y++HWP    ++        S +A + DLE IW   I+K L+IP +DL  YR IL++ D+  R  ++ ++ ML+  + FS IV+ QE+VC T+ +GL +ACVV++ +   S+ CVE+G+S    R+ + YG SD+   F  LL R+ FP  +  + +  D   +Q ++E F   C L    +   S L       D   R R          + +G E + A +ALF+PS       K    QH    + +P+DP D+ YL  T + +D+  + + E   +    G       +     +DP                              +H     +    G C      ++  P+  L    A+ +   K+L    ++   ID  T  ET +++ S IL  G  + FPG  E L+    N + PS  +  E VEVI       +     AWKG +++  +    ++WI  ++W ++G R +RE+A F+W
Sbjct:   51 IVVINPGSKTLRIGRATDTFPAVVPHVIARRQKQPS----QPRYEDPWLLREGLNRPES--NEQRQNGLKMVDQAIWSKKMS--NGVRRTPVSAE---QARSYNRQVRPAVLESSSRVKWTNTSHQPEFLIGEEALHVNPADSYSIHWPVCRAQLNIHSGPGGSLSAVLADLEAIWSHTIQKFLEIPLKDLKYYRCILLVPDIYNRQHVKELVNMLLVNMGFSAIVVHQESVCATFGSGLSSACVVDVGDQKTSLCCVEDGVSHRNSRLCVAYGGSDVTRCFFWLLQRVSFPYRECLLSNRLDCMLLQQLKETF---CHL----DQDISGLQ------DHEFRTRFPDSPTLLYQLRLGDEKLQAPMALFYPSTFGIVGQKMTTLQHR--SQGDPEDPHDEHYLLSTQSKQDQSSKAIAERRTLPKSIGLDG----ESGSQGVDPP--------------------------MRGVHVQDAELGHPQGDCLMGGAEAEELPSAFLSRKSAMTQFEGKALGLDKAILYSIDCCTSDETKRKMYSSILVVGGGLMFPGAQEFLQHRILNKMPPSFRRVVENVEVITR--PKDMDPRLIAWKGGAVLACLDTTQEMWIYQQEWQRFGVRMLRERAAFVW 628          
BLAST of Actin-related protein 8 vs. TrEMBL
Match: A0A5K4F5T9 (Uncharacterized protein OS=Schistosoma mansoni OX=6183 PE=4 SV=1)

HSP 1 Score: 198.364 bits (503), Expect = 1.543e-50
Identity = 134/420 (31.90%), Postives = 208/420 (49.52%), Query Frame = 1
Query:   79 ENIIVIHPSATKLRFGRSNDSEPIIIPHCIARKCKIISKVIRQPKIPDNRASTLLNTKFNNAIKLASIAMKSSSIEVLQPFKEQPTINELIHMNKQYLKXXXXXXXX----XXHRVYSEEFYIGKEALEVPIEANYNLHWPFWDDKISDKYSKTAAVKDLEDIWRMGIEKSLKIPSEDLANYRIILVISDLIIRSEIRWIIEMLINELKFSNIVLQQENVCITYSTGLPTACVVNMHENSISISCVEEGISIPEGRIKLLYGTSDILCLFHSLLIRIGFPK----TAIESYSDYQGVQSIEELFATACELIPSNESKASKLNGNRKSIDPNGRIRCQSIDMY-----IGSEAIIAGLALFHPSLI-------------CKDSPKY--QFQHNLADESEPDDPFDDLYLTLTSRDRKKQRL 1254
            EN+++I P +  LR GR+ +  P   PHCIARK K       +P I   +A+       N++    S+    S +  L      P  N L  +    L+   + D        +    +EFY   +A    ++  Y+++WP     +S   + TA ++DLEDIW   +EK + IP  +L+NYR ILVISD+  R+EIR+++ +L+N LKF  + + Q +VC TY  GLPTACV+N+ E   S+SCVE+G++  E RI L  G SD+L +FHSL++  GF      T    Y     V+ +  L   + +   S   + ++ N   + I P       + D Y        +     ++  HPS +             C  S +    +Q      SEPDDPFDD+Y++LT+R+R+K+ L
Sbjct:    9 ENVVIIEPGSFHLRIGRAVEILPKRFPHCIARKPKPNVPPCVEPIISRQKAAC------NSSSLQESVNTIRSYVNTLFNLSYLPESNGLPAVTPSRLEHTEIEDTKLFEWESNTPSGQEFYALNDAFNRGLKDGYHINWPMRYGFLSTSANYTAVLQDLEDIWSTALEKHVGIPRSNLSNYRAILVISDVYKRNEIRYLVHLLLNRLKFGRVFVHQASVCATYGIGLPTACVINIGEQKTSVSCVEDGVAHTETRIILPVGRSDVLRVFHSLVLPNGFCNNEGCTVDLKYEHLSDVEDLRTLMENSVQCTISLLCQQNEKNKLDEEIQPKANESLLNNDFYNITLQWTHKQNQYDISSLHPSTVLLSHILPFACISSCVPSKEVCCTYQVPSLQSSEPDDPFDDMYISLTARERRKRGL 422          
BLAST of Actin-related protein 8 vs. TrEMBL
Match: A0A2D0R2P3 (Actin-related protein 8 OS=Ictalurus punctatus OX=7998 GN=actr8 PE=3 SV=1)

HSP 1 Score: 199.134 bits (505), Expect = 2.028e-50
Identity = 165/624 (26.44%), Postives = 284/624 (45.51%), Query Frame = 1
Query:   85 IIVIHPSATKLRFGRSNDSEPIIIPHCIARKCK-----------IISKVIRQPKIPDNRASTLLNTKFNNAI---KLASIAMKSS-SIEVLQPFKEQPTINELIHMNKQYLKXXXXXXXXXXHRVYSEEFYIGKEALEVPIEANYNLHWPFWDDKI----SDKYSKTAAVKDLEDIWRMGIEKSLKIPSEDLANYRIILVISDLIIRSEIRWIIEMLINELKFSNIVLQQENVCITYSTGLPTACVVNMHENSISISCVEEGISIPEGRIKLLYGTSDILCLFHSLLIRIGFP--KTAIESYSDYQGVQSIEELFATACELIPSNESKASKLNGNRKSIDPNGRIRCQSIDMYIGSEAIIAGLALFHPSLICKDSPKY-QFQHNLADESEPDDPFDDLYLTLTSRDRKKQRLDEXXXXXXXXXXXXXXXFQQAGDEIDPDEDXXXXXXXXXXXXXXXXXXXXXXXXXXKLHRISNLIPESPGSCSQNDPNKALPLNDAIVKSINKSLSSLAVVIDNI-----TETSQQL-CSVILAGEPIEFPGCVELLE----NSLKPSLSQCGE-VEVIHNDFTDGISAHSAAWKGASMITLVGYCDDLWISGKDWNKYGSRAIREKAPFLW 1857
            ++VI P +  LR GR+ D+ P+ IPH IAR+ K           +I + + +P+  + R + L     + AI   K++S A ++  S E  + +  Q     L   ++Q             + V+  E+ +G EAL V     Y+LHWP    ++        S TA + DLE IW   I+K L++P +DL  YR IL+I D+  R  ++ ++ ML+ ++ FS I++ QE+VC  + +GL +ACVV++ +   S+ CVE+G+S    R+ L YG SD+   F  L+ R GFP  +  +    D   +Q ++E F   C L   ++      +   ++  P   +      + +G E + A +ALF+P+       K    QH    + +P+DP D+ YL  T   + +              G       Q GD+ +    +                           H   + +P   G+  ++ P+  L    A+ +   K+L     ++ +I      ET +++  SV++ G  + F G  E L+    N + PS  +  E VEVI       +     AWKG +++  +    +LWI   +W ++G+R +RE+A F+W
Sbjct:   97 VVVISPGSQTLRIGRATDTLPLTIPHVIARRHKRPGQTRYEDVWLIREGLNRPESGEQRQNGL--KMVDQAIWSKKMSSGARRTPVSAEQARVYNRQVRPAVLDPNSRQKW----------TNTVHQPEYLVGDEALHVNPTDCYSLHWPICHGQLNVHSGPGGSLTAVLADLETIWSQAIQKLLEVPLKDLKYYRCILLIPDIYNRQHVKAVLNMLLVKMGFSAIIVHQESVCAAFGSGLSSACVVDVGDQKTSVCCVEDGVSHRNSRLCLAYGGSDVTRCFFWLMQRAGFPYRECQLGKRLDCMLLQQLKETF---CHL---DQDICGLQDHEFRTRFPESPVIL--YQLRLGDEKLQAPMALFYPAAFGIVGQKMTTLQHR--SQGDPEDPHDEHYLLSTQSKQDQSSKSMERKGLPKPSGFEGETCSQGGDQTERGTQDVELG-----------------------HSQGDALPS--GADPEDTPSVLLSRKSAMTQFEGKALGLDKAILHSIDCCASDETKRKMYSSVLVVGGGLLFHGAQEFLQHRILNKMPPSFRRMVENVEVITR--PKDMDPRLTAWKGGAVLACLDTTQELWIHQGEWQRFGARMLRERAAFVW 671          
BLAST of Actin-related protein 8 vs. Ensembl Cavefish
Match: actr8 (actin related protein 8 [Source:NCBI gene;Acc:103039035])

HSP 1 Score: 197.208 bits (500), Expect = 1.864e-53
Identity = 173/626 (27.64%), Postives = 279/626 (44.57%), Query Frame = 1
Query:   85 IIVIHPSATKLRFGRSNDSEPIIIPHCIARKCKIISKVIRQPKIPDNRASTLLNTKFN---------NAIKLASIAMKSSSIEVLQPFKEQPTINELIHMNKQYLKXXXXXXXXX---XHRVYSEEFYIGKEALEVPIEANYNLHWPF-WDD---KISDKYSKTAAVKDLEDIWRMGIEKSLKIPSEDLANYRIILVISDLIIRSEIRWIIEMLINELKFSNIVLQQENVCITYSTGLPTACVVNMHENSISISCVEEGISIPEGRIKLLYGTSDILCLFHSLLIRIGFPKTAIESYSDYQGVQSI-----EELFATACELIPSNESKASKLNGNRKSIDPNGRIRCQSIDMYIGSEAIIAGLALFHPSLICKDSPKY-QFQHNLADESEPDDPFDDLYLTLTSRDRKKQRLDEXXXXXXXXXXXXXXXFQQAGDEIDPDEDXXXXXXXXXXXXXXXXXXXXXXXXXXKLHRISNLIPE-------SPGSCSQNDPNKALPLNDAIVKSINKSLSSLAVVIDNITETSQQLCSVIL-AGEPIEFPGCVELLE----NSLKPSLSQCGE-VEVIHNDFTDGISAHSAAWKGASMITLVGYCDDLWISGKDWNKYGSRAIREKAPFLW 1857
            ++V+HP +  LR GR+ D+ P+ +PH IAR+ K+ S    Q +  D+R   LL    N         N +K+   A+ S  +      +  P   E   +  + ++   L   S     +  +  E+ +G EAL V     Y++HWP  W           S TA + DLE IW   I+K L+IP +DL  YR IL+I D+  R  ++ ++ ML+ ++ FS IV+ QE+VC  + +GL +ACV+++ +   S+ CVE+G+S    R+ L YG SD+   F  L+ R GFP      Y D Q    +     ++L  T C L   ++      +   ++  P   +      + IG E + A +ALF+P+       K    QH      +P+DP D+ YL  T   + +              G    +  Q GD+++       +  +S S+                   +    PE       S  S       KAL L+ AI+ SI+   S          ET +++ S IL  G  + F G  E L+    N + PS  +  E VEVI       +     AWKG +++  +    +LWI  ++W ++G+R +RE+  F+W
Sbjct:   51 VVVLHPGSQTLRIGRATDTLPVTVPHVIARRHKLPS----QSRYEDSR---LLREGLNRPESAEQRQNGLKMVDQAIWSKKMS--NGARRTPVSAEQARVYNRQIRPAVLDSNSRLKWTNTAHQPEYLVGDEALYVNPTDCYSIHWPICWGQLNVHSGPGGSLTAVLADLETIWSHAIQKLLEIPLKDLKYYRCILLIPDIYNRQHVKEVVNMLLVKMGFSAIVVHQESVCAAFGSGLSSACVIDVGDQKTSVCCVEDGVSHRNSRLCLAYGGSDVTLCFFWLMQRAGFP------YRDCQLTNRVDCILLQQLKETFCHL---DQDICGLQDHEFRTRFPESPVLL--YQLRIGDEKLQAPMALFYPAAFGIVGQKMTTLQHR--SPGDPEDPHDEHYLLSTQSKQDQSSKAMERKGFSKPPGFEGESSSQGGDQMERGNHGQEDLGHSQSDCL-----------------VGGTDPEETPSVLLSRKSAMTQFEGKALGLDKAILHSIDCCASD---------ETKRKMYSSILVVGGGLLFHGAQEFLQHRILNKMPPSFRRLVENVEVITR--PKDMDPRLTAWKGGAVLACLDTTQELWIHQREWIRFGARMLRERTAFVW 626          
BLAST of Actin-related protein 8 vs. Ensembl Cavefish
Match: actr8 (actin related protein 8 [Source:NCBI gene;Acc:103039035])

HSP 1 Score: 161.77 bits (408), Expect = 1.760e-41
Identity = 164/626 (26.20%), Postives = 265/626 (42.33%), Query Frame = 1
Query:   85 IIVIHPSATKLRFGRSNDSEPIIIPHCIARKCKIISKVIRQPKIPDNRASTLLNTKFN---------NAIKLASIAMKSSSIEVLQPFKEQPTINELIHMNKQYLKXXXXXXXXX---XHRVYSEEFYIGKEALEVPIEANYNLHWPF-WDD---KISDKYSKTAAVKDLEDIWRMGIEKSLKIPSEDLANYRIILVISDLIIRSEIRWIIEMLINELKFSNIVLQQENVCITYSTGLPTACVVNMHENSISISCVEEGISIPEGRIKLLYGTSDILCLFHSLLIRIGFPKTAIESYSDYQGVQSI-----EELFATACELIPSNESKASKLNGNRKSIDPNGRIRCQSIDMYIGSEAIIAGLALFHPSLICKDSPKY-QFQHNLADESEPDDPFDDLYLTLTSRDRKKQRLDEXXXXXXXXXXXXXXXFQQAGDEIDPDEDXXXXXXXXXXXXXXXXXXXXXXXXXXKLHRISNLIPE-------SPGSCSQNDPNKALPLNDAIVKSINKSLSSLAVVIDNITETSQQLCSVIL-AGEPIEFPGCVELLE----NSLKPSLSQCGE-VEVIHNDFTDGISAHSAAWKGASMITLVGYCDDLWISGKDWNKYGSRAIREKAPFLW 1857
            ++V+HP +  LR GR+ D+ P+ +PH IAR+ K+ S    Q +  D+R   LL    N         N +K+   A+ S  +      +  P   E   +  + ++   L   S     +  +  E+ +G EAL V     Y++HWP  W           S TA + DLE IW   I+K L+IP +DL    + +++                     FS IV+ QE+VC  + +GL +ACV+++ +   S+ CVE+G+S    R+ L YG SD+   F  L+ R GFP      Y D Q    +     ++L  T C L   ++      +   ++  P   +      + IG E + A +ALF+P+       K    QH      +P+DP D+ YL  T   + +              G    +  Q GD+++       +  +S S+                   +    PE       S  S       KAL L+ AI+ SI+   S          ET +++ S IL  G  + F G  E L+    N + PS  +  E VEVI       +     AWKG +++  +    +LWI  ++W ++G+R +RE+  F+W
Sbjct:   51 VVVLHPGSQTLRIGRATDTLPVTVPHVIARRHKLPS----QSRYEDSR---LLREGLNRPESAEQRQNGLKMVDQAIWSKKMS--NGARRTPVSAEQARVYNRQIRPAVLDSNSRLKWTNTAHQPEYLVGDEALYVNPTDCYSIHWPICWGQLNVHSGPGGSLTAVLADLETIWSHAIQKLLEIPLKDLKKGIVYILL---------------------FS-IVVHQESVCAAFGSGLSSACVIDVGDQKTSVCCVEDGVSHRNSRLCLAYGGSDVTLCFFWLMQRAGFP------YRDCQLTNRVDCILLQQLKETFCHL---DQDICGLQDHEFRTRFPESPVLL--YQLRIGDEKLQAPMALFYPAAFGIVGQKMTTLQHR--SPGDPEDPHDEHYLLSTQSKQDQSSKAMERKGFSKPPGFEGESSSQGGDQMERGNHGQEDLGHSQSDCL-----------------VGGTDPEETPSVLLSRKSAMTQFEGKALGLDKAILHSIDCCASD---------ETKRKMYSSILVVGGGLLFHGAQEFLQHRILNKMPPSFRRLVENVEVITR--PKDMDPRLTAWKGGAVLACLDTTQELWIHQREWIRFGARMLRERTAFVW 604          
BLAST of Actin-related protein 8 vs. Ensembl Cavefish
Match: actr8 (actin related protein 8 [Source:NCBI gene;Acc:103039035])

HSP 1 Score: 157.147 bits (396), Expect = 4.415e-40
Identity = 103/321 (32.09%), Postives = 161/321 (50.16%), Query Frame = 1
Query:   85 IIVIHPSATKLRFGRSNDSEPIIIPHCIARKCKIISKVIRQPKIPDNRASTLLNTKFN---------NAIKLASIAMKSSSIEVLQPFKEQPTINELIHMNKQYLKXXXXXXXXX---XHRVYSEEFYIGKEALEVPIEANYNLHWPF-WDD---KISDKYSKTAAVKDLEDIWRMGIEKSLKIPSEDLANYRIILVISDLIIRSEIRWIIEMLINELKFSNIVLQQENVCITYSTGLPTACVVNMHENSISISCVEEGISIPEGRIKLLYGTSDILCLFHSLLIRIGFPKTAIESYSDYQGVQSI-----EELFATACEL 984
            ++V+HP +  LR GR+ D+ P+ +PH IAR+ K+ S    Q +  D+R   LL    N         N +K+   A+ S  +      +  P   E   +  + ++   L   S     +  +  E+ +G EAL V     Y++HWP  W           S TA + DLE IW   I+K L+IP +DL  YR IL+I D+  R  ++ ++ ML+ ++ FS IV+ QE+VC  + +GL +ACV+++ +   S+ CVE+G+S    R+ L YG SD+   F  L+ R GFP      Y D Q    +     ++L  T C L
Sbjct:   51 VVVLHPGSQTLRIGRATDTLPVTVPHVIARRHKLPS----QSRYEDSR---LLREGLNRPESAEQRQNGLKMVDQAIWSKKMS--NGARRTPVSAEQARVYNRQIRPAVLDSNSRLKWTNTAHQPEYLVGDEALYVNPTDCYSIHWPICWGQLNVHSGPGGSLTAVLADLETIWSHAIQKLLEIPLKDLKYYRCILLIPDIYNRQHVKEVVNMLLVKMGFSAIVVHQESVCAAFGSGLSSACVIDVGDQKTSVCCVEDGVSHRNSRLCLAYGGSDVTLCFFWLMQRAGFP------YRDCQLTNRVDCILLQQLKETFCHL 356          

HSP 2 Score: 58.5362 bits (140), Expect = 1.858e-8
Identity = 41/130 (31.54%), Postives = 65/130 (50.00%), Query Frame = 1
Query: 1486 NKALPLNDAIVKSINKSLSSLAVVIDNITETSQQLCSVILA-GEPIEFPGCVELLE----NSLKPSLSQCGE-VEVIHNDFTDGISAHSAAWKGASMITLVGYCDDLWISGKDWNKYGSRAIREKAPFLW 1857
             KAL L+ AI+ SI+   S          ET +++ S IL  G  + F G  E L+    N + PS  +  E VEVI       +     AWKG +++  +    +LWI  ++W ++G+R +RE+  F+W
Sbjct:  461 GKALGLDKAILHSIDCCASD---------ETKRKMYSSILVVGGGLLFHGAQEFLQHRILNKMPPSFRRLVENVEVITR--PKDMDPRLTAWKGGAVLACLDTTQELWIHQREWIRFGARMLRERTAFVW 579          
BLAST of Actin-related protein 8 vs. Ensembl Sea Lamprey
Match: actr8 (actin related protein 8 [Source:NCBI gene;Acc:326866])

HSP 1 Score: 107.071 bits (266), Expect = 2.940e-25
Identity = 101/401 (25.19%), Postives = 177/401 (44.14%), Query Frame = 1
Query:  697 SNIVLQQENVCITYSTGLPTACVVNMHENSISISCVEEGISIPEGRIKLLYGTSDILCLFHSLLIRIGFPKTAIESYSDYQGVQSIEELFATACELIPSNESKASKLNGNRKSIDPNGRIRCQSIDMYIGSEAIIAGLALFHPSLICKDSPKYQFQHNLADESEPDDPFDDLYLTLTSRDRKKQRLDEXXXXXXXXXXXXXXXFQQAGDEID--------PDEDXXXXXXXXXXXXXXXXXXXXXXXXXXKLHRISNLIPESPGSCSQNDPNKALPLNDAIVKSINKSLSSLAVVIDNITETSQQLCSVILA-GEPIEFPGCVELLE----NSLKPSLSQCGE-VEVIHNDFTDGISAHSAAWKGASMITLVGYCDDLWISGKDWNKYGSRAIREKAPFLW 1857
            +  ++ QE+VC ++  GL  ACVV++ +   SI CVE+GIS    R+ L YG SD+   F+ L+ R GFP    +  ++      +++L    C L    +   S    +   +     +        +G E + A +++F+P++      +       + + +P+DP+D+ YL  T    K+++  +           S  + + AG   +        PD D G +     +++ +   +  + S   KL              S +   KAL L+ A++ SI+   S          ET +++ S IL  G  + FPG  E L+    N + PS  +  E VEVI             AWKG  ++  +    +LWI  ++W ++G R +RE+APF+W
Sbjct:    1 AGAMVHQESVCASFGCGLSCACVVDIGDQKTSICCVEDGISHRHTRLFLEYGGSDVTRCFYLLMQRSGFPYRECQ-LANRMNALLLQQLKENFCHL----DQDISGFQDHEFQVRQPDSVAL-LYQFKLGDEKLQAPMSMFYPAVFGIVGQRMTLTQQRS-QGDPEDPYDEHYLLATQS--KQEQAAKAVAERKALAKHSAADSEGAGAPAEASEGAGRAPDGDQGPSRGAGETHHLNQPGAPSLLSRKLKL-------------ASPHFEGKALGLDKAVLHSIDCCSSE---------ETKRKMYSSILVVGGGLLFPGAQEFLQHRIINKMPPSFRRLVETVEVITR--PKDTDPRLTAWKGGVVLACLDTAQELWIHRREWERFGVRMLRERAPFVW 368          
BLAST of Actin-related protein 8 vs. Ensembl Yeast
Match: ARP8 (Nuclear actin-related protein involved in chromatin remodeling; component of chromatin-remodeling enzyme complexes; has mRNA binding activity [Source:SGD;Acc:S000005667])

HSP 1 Score: 86.6557 bits (213), Expect = 7.194e-18
Identity = 86/370 (23.24%), Postives = 158/370 (42.70%), Query Frame = 1
Query:   88 IVIHPSATKLRFGRSNDSEPIIIPHCIARKCKIISK----------VIRQPKIPDNRASTLLNTKFNNAIKLASIAMKSSSIEVLQPFKEQPTINELIHMNKQYLKXXXXXXXXXXHRVYSE-EFYIGKEALEVPIEANYNLHWPFWDDKISDK--YSKTAA--VKDLEDIWRMGIE-KSLKIPSEDLANYRIILVISDLIIRSEIRWIIEMLINELKFSNIVLQQENVCITYSTGLPTA-CVVNMHENSISISCVEEGISIPEGRIKLLYGTSDILCLFHSLLIRIGFP--KTAIESYSDYQGVQSIEELFATACELIPSNESKASKLNG--NRKSIDPNGRIRCQSIDMYIGSEAIIAGLALFHPSLI 1134
            IVIHP +  ++ G   D  P+++P+C+A   K +            + R+     N   + +   F   ++     +  ++ E +  F E      +   N            S I  ++ + + Y G +AL   ++  + +  PF     + K  Y K+ A  + D+  +    +  ++L +       Y+++LVI D+  +S +   I +L+ EL+F  + + QE++   Y  G+ T+ CVVN+      I+CV+EG  +    I L YG  DI  LF   L++  FP     I+S   +   + +++ F T       +   A +L    NR    P  +   +  D     E ++A LALF P + 
Sbjct:  269 IVIHPGSNSIKIGFPKDDHPVVVPNCVAVPKKWLDLENSEHVENVCLQREQSEEFNNIKSEMEKNFRERMRYYKRKVPGNAHEQVVSFNENSKPEIISEKND----------PSPIEWIFDDSKLYYGSDALRC-VDEKFVIRKPFRGGSFNVKSPYYKSLAELISDVTKLLEHALNSETLNVKPTKFNQYKVVLVIPDIFKKSHVETFIRVLLTELQFQAVAIIQESLATCYGAGISTSTCVVNIGAAETRIACVDEGTVLEHSAITLDYGGDDITRLFALFLLQSDFPLQDWKIDSKHGWLLAERLKKNFTTF-----QDADVAVQLYNFMNRSPNQPTEKYEFKLFD-----EVMLAPLALFFPQIF 617          
BLAST of Actin-related protein 8 vs. Ensembl Nematostella
Match: EDO47930 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RKL9])

HSP 1 Score: 131.724 bits (330), Expect = 5.001e-32
Identity = 102/364 (28.02%), Postives = 171/364 (46.98%), Query Frame = 1
Query:   82 NIIVIHPSATKLRFGRSNDSEPIIIPHCIARKCKIISKVIRQPKI----PDNRASTLLNTKFNNAIKLASIAMKSSSIEVLQPFKEQPTINELIHMNKQY---LKXXXXXXXXXXHRVYSEEFYIGKEALEVPIEANYNLHWPFWDDKI----SDKYSKTAAVKDLEDIWRMGIEKSLKIPSEDLANYRIILVISDLIIRSEIRWIIEMLINELKFSNIVLQQENVCITYSTGLPTACVVNMHENSISISCVEEGISIPEGRIKLLYGTSDILCLFHSLLIRIGFP--KTAIESYSDYQGVQSIEELFATACELIPSNESKASKLNGNRKSIDPNGRIRCQSIDMYIGSEAIIAGLALFHPSLI 1134
            NIIV+HP +T L  GRS D  P    H +A   ++       P I     D    +   T+   A+ +   A+ S    +    K+     ++   N      L  +  S +             G++AL +  +  Y L WP    ++        S T+    +E IW   I+  LKIP +DL  YR +LV+ D   ++ I+ ++++LIN L FS+++LQQE+V  T+  GL +ACVV++ +   SI CVE+G+ +P  R+ L YG  DI   F+ L+ R+ FP  +  + +  D   +Q ++E F    + I        +++  R++          + ++ IG EA+ A +A+F P L 
Sbjct:    8 NIIVLHPGSTTLWLGRSTDHLPTSYHHVVA--WRLPEGCANGPSIHMVERDGIHHSDSETQRELALSVVEQAIWSRKSNLGNSRKQHVPATQVATYNANVEAELLDEEESSVEWSDVSQKPSCLTGEQALYIDPQEPYTLLWPMKHGRLNLHKGPGGSLTSICIAIEAIWSRAIQTCLKIPLKDLTLYRAVLVVPDSFAKNHIKEMVKILINGLGFSSVILQQESVSSTFGCGLSSACVVDVGDEKTSICCVEDGLIVPSSRLWLNYGGRDITHCFYWLMKRVNFPYKECDVNNMLDAIMLQELKETFCHLSQEIVGGRVHEFQVHHPRRAPI--------AYNLKIGDEAMQAPMAMFFPQLF 361          

HSP 2 Score: 57.7658 bits (138), Expect = 1.307e-8
Identity = 27/91 (29.67%), Postives = 50/91 (54.95%), Query Frame = 1
Query: 1594 SVILAGEPIEFPGCVELLENSLKPSLSQCGEVEVIHNDFT---DGISAHSAAWKGASMITLVGYCDDLWISGKDWNKYGSRAIREKAPFLW 1857
            S++L G    F G   +L+  ++  L Q     V   + T     +   + AWKG ++++++    +LW++ ++WN  G RA+REK+PF+W
Sbjct:  495 SILLIGGGFNFNGAAGVLQARVQSKLPQYFRKMVDQVEVTAKPKEMDPRTVAWKGGAILSILDSAQELWLTEREWNVIGVRALREKSPFVW 585          
BLAST of Actin-related protein 8 vs. Ensembl Medaka
Match: actr8 (actin related protein 8 [Source:NCBI gene;Acc:101160905])

HSP 1 Score: 160.999 bits (406), Expect = 5.057e-41
Identity = 119/404 (29.46%), Postives = 197/404 (48.76%), Query Frame = 1
Query:   85 IIVIHPSATKLRFGRSNDSEPIIIPHCIARKCKIISKVIRQPK------IPDNRASTLLNTKFNNAIKLASIAMKSSSIEVLQPFKEQPTINELIHMNKQYLKXX---XXXXXXXXHRVYSEEFYIGKEALEVPIEANYNLHWPFWDDKI----SDKYSKTAAVKDLEDIWRMGIEKSLKIPSEDLANYRIILVISDLIIRSEIRWIIEMLINELKFSNIVLQQENVCITYSTGLPTACVVNMHENSISISCVEEGISIPEGRIKLLYGTSDILCLFHSLLIRIGFP--KTAIESYSDYQGVQSIEELFATACELIPSNESKASKLNGNRKSIDPNGRIRCQSIDMYIGSEAIIAGLALFHPSLICKDSPKYQ-FQHNLADESEPDDPFDDLYLTLTSRDRKKQ 1248
            +IVI+P +  +R GR+ D+ P+ +PH IAR+     K   QP+      I D       N +  N +K+   A+ S  +      +  P   E        ++     S S     +  +   + +G+EAL V     YN+HWP    +         S TA + DLE IW   ++K L+IP +DL  YR IL++ ++  R  ++ ++ ML+  + FS I++ QE+VC T+ +GL +ACVV++ +   S+ CVE+G+S    R+ L YG SD+   F  LL R GFP     +    D Q +Q ++E+F   C L   N+  +   +   ++  P        I +  G E + A + LF+P+       K    QH    + +P+DP D+ YL L+++ ++ Q
Sbjct:   51 VIVINPGSRSVRIGRATDTLPVTVPHVIARR----HKQSGQPRHEDPWLIRDGLNKPESNEQRQNGLKMVDQAIWSKKMS--NGVRRTPVSAEQARAYNCQIRPAVLDSSSRGKWTNTGHHPPYLVGEEALYVNPSDCYNIHWPIVRGQFNIHSGPGGSMTAVLADLEAIWSHVLQKHLEIPLKDLKYYRCILLVPNIYNRQHVKEVVNMLLLNMGFSAIIVHQESVCATFGSGLSSACVVDVGDQKTSVCCVEDGVSHRNSRLCLAYGGSDVTRTFFWLLQRAGFPYRDCQLSKRLDCQLLQHLKEIF---CHL---NQDISGLQDHEFQTRFPEAPALLYQIRL--GDEKLQAPMGLFYPTTFGIVGQKMTLLQHRY--QGDPEDPHDEHYL-LSTQSKQDQ 437          

HSP 2 Score: 53.5286 bits (127), Expect = 7.091e-7
Identity = 37/130 (28.46%), Postives = 63/130 (48.46%), Query Frame = 1
Query: 1486 NKALPLNDAIVKSINKSLSSLAVVIDNITETSQQL-CSVILAGEPIEFPGCVELLE----NSLKPSLSQ-CGEVEVIHNDFTDGISAHSAAWKGASMITLVGYCDDLWISGKDWNKYGSRAIREKAPFLW 1857
            +KAL L+ AI+ SI+   S          ET +++  S+++ G  + F G  E L     N + PS  +    VEVI       +      WKG +++  +    ++WI   +W ++G R +RE+A F+W
Sbjct:  523 SKALGLDKAILHSIDCCASD---------ETKRKMYSSILIVGGGLMFQGAQEFLLHRIINKMPPSFRRLVDNVEVITR--PKDMDPRLIMWKGGAVLACLDTTQEMWIHQTEWQRFGVRMLRERAAFVW 641          
BLAST of Actin-related protein 8 vs. Ensembl Medaka
Match: actr8 (actin related protein 8 [Source:NCBI gene;Acc:101160905])

HSP 1 Score: 154.066 bits (388), Expect = 1.168e-38
Identity = 119/414 (28.74%), Postives = 198/414 (47.83%), Query Frame = 1
Query:   85 IIVIHPSATKLRFGRSNDSEPIIIPHCIARKCKIISKVIRQPK------IPDNRASTLLNTKFNNAIKLASIAMKSSSIEVLQPFKEQPTINELIHMNKQYLKXX---XXXXXXXXHRVYSEEFYIGKEALEVPIEANYNLHWPFWDDKI----SDKYSKTAAVKDLEDIWRMGIEKSLKIPSEDLANY----------RIILVISDLIIRSEIRWIIEMLINELKFSNIVLQQENVCITYSTGLPTACVVNMHENSISISCVEEGISIPEGRIKLLYGTSDILCLFHSLLIRIGFP--KTAIESYSDYQGVQSIEELFATACELIPSNESKASKLNGNRKSIDPNGRIRCQSIDMYIGSEAIIAGLALFHPSLICKDSPKYQ-FQHNLADESEPDDPFDDLYLTLTSRDRKKQ 1248
            +IVI+P +  +R GR+ D+ P+ +PH IAR+     K   QP+      I D       N +  N +K+   A+ S  +      +  P   E        ++     S S     +  +   + +G+EAL V     YN+HWP    +         S TA + DLE IW   ++K L+IP +DL +Y          R IL++ ++  R  ++ ++ ML+  + FS I++ QE+VC T+ +GL +ACVV++ +   S+ CVE+G+S    R+ L YG SD+   F  LL R GFP     +    D Q +Q ++E+F   C L   N+  +   +   ++  P        I +  G E + A + LF+P+       K    QH    + +P+DP D+ YL L+++ ++ Q
Sbjct:   51 VIVINPGSRSVRIGRATDTLPVTVPHVIARR----HKQSGQPRHEDPWLIRDGLNKPESNEQRQNGLKMVDQAIWSKKMS--NGVRRTPVSAEQARAYNCQIRPAVLDSSSRGKWTNTGHHPPYLVGEEALYVNPSDCYNIHWPIVRGQFNIHSGPGGSMTAVLADLEAIWSHVLQKHLEIPLKDLKHYFRLIIIFFYYRCILLVPNIYNRQHVKEVVNMLLLNMGFSAIIVHQESVCATFGSGLSSACVVDVGDQKTSVCCVEDGVSHRNSRLCLAYGGSDVTRTFFWLLQRAGFPYRDCQLSKRLDCQLLQHLKEIF---CHL---NQDISGLQDHEFQTRFPEAPALLYQIRL--GDEKLQAPMGLFYPTTFGIVGQKMTLLQHRY--QGDPEDPHDEHYL-LSTQSKQDQ 447          

HSP 2 Score: 53.9138 bits (128), Expect = 5.524e-7
Identity = 37/130 (28.46%), Postives = 63/130 (48.46%), Query Frame = 1
Query: 1486 NKALPLNDAIVKSINKSLSSLAVVIDNITETSQQL-CSVILAGEPIEFPGCVELLE----NSLKPSLSQ-CGEVEVIHNDFTDGISAHSAAWKGASMITLVGYCDDLWISGKDWNKYGSRAIREKAPFLW 1857
            +KAL L+ AI+ SI+   S          ET +++  S+++ G  + F G  E L     N + PS  +    VEVI       +      WKG +++  +    ++WI   +W ++G R +RE+A F+W
Sbjct:  533 SKALGLDKAILHSIDCCASD---------ETKRKMYSSILIVGGGLMFQGAQEFLLHRIINKMPPSFRRLVDNVEVITR--PKDMDPRLIMWKGGAVLACLDTTQEMWIHQTEWQRFGVRMLRERAAFVW 651          
BLAST of Actin-related protein 8 vs. Planmine SMEST
Match: SMESG000050181.1 (SMESG000050181.1)

HSP 1 Score: 1108.98 bits (2867), Expect = 0.000e+0
Identity = 602/602 (100.00%), Postives = 602/602 (100.00%), Query Frame = 1
Query:   52 MSKITSFPRENIIVIHPSATKLRFGRSNDSEPIIIPHCIARKCKIISKVIRQPKIPDNRASTLLNTKFNNAIKLASIAMKSSSIEVLQPFKEQPTINELIHMNKQYLKXXXXXXXXXXHRVYSEEFYIGKEALEVPIEANYNLHWPFWDDKISDKYSKTAAVKDLEDIWRMGIEKSLKIPSEDLANYRIILVISDLIIRSEIRWIIEMLINELKFSNIVLQQENVCITYSTGLPTACVVNMHENSISISCVEEGISIPEGRIKLLYGTSDILCLFHSLLIRIGFPKTAIESYSDYQGVQSIEELFATACELIPSNESKASKLNGNRKSIDPNGRIRCQSIDMYIGSEAIIAGLALFHPSLICKDSPKYQFQHNLADESEPDDPFDDLYLTLTSRDRKKQRLDEXXXXXXXXXXXXXXXFQQAGDEIDPDEDXXXXXXXXXXXXXXXXXXXXXXXXXXKLHRISNLIPESPGSCSQNDPNKALPLNDAIVKSINKSLSSLAVVIDNITETSQQLCSVILAGEPIEFPGCVELLENSLKPSLSQCGEVEVIHNDFTDGISAHSAAWKGASMITLVGYCDDLWISGKDWNKYGSRAIREKAPFLW 1857
            MSKITSFPRENIIVIHPSATKLRFGRSNDSEPIIIPHCIARKCKIISKVIRQPKIPDNRASTLLNTKFNNAIKLASIAMKSSSIEVLQPFKEQPTINELIHMNKQYLKLDSLSDISSIHRVYSEEFYIGKEALEVPIEANYNLHWPFWDDKISDKYSKTAAVKDLEDIWRMGIEKSLKIPSEDLANYRIILVISDLIIRSEIRWIIEMLINELKFSNIVLQQENVCITYSTGLPTACVVNMHENSISISCVEEGISIPEGRIKLLYGTSDILCLFHSLLIRIGFPKTAIESYSDYQGVQSIEELFATACELIPSNESKASKLNGNRKSIDPNGRIRCQSIDMYIGSEAIIAGLALFHPSLICKDSPKYQFQHNLADESEPDDPFDDLYLTLTSRDRKKQRLDENGGVAGGAGGISNGNFQQAGDEIDPDEDNGNNHNNSHSNNNSHSNSNYINSANSKLHRISNLIPESPGSCSQNDPNKALPLNDAIVKSINKSLSSLAVVIDNITETSQQLCSVILAGEPIEFPGCVELLENSLKPSLSQCGEVEVIHNDFTDGISAHSAAWKGASMITLVGYCDDLWISGKDWNKYGSRAIREKAPFLW
Sbjct:    1 MSKITSFPRENIIVIHPSATKLRFGRSNDSEPIIIPHCIARKCKIISKVIRQPKIPDNRASTLLNTKFNNAIKLASIAMKSSSIEVLQPFKEQPTINELIHMNKQYLKLDSLSDISSIHRVYSEEFYIGKEALEVPIEANYNLHWPFWDDKISDKYSKTAAVKDLEDIWRMGIEKSLKIPSEDLANYRIILVISDLIIRSEIRWIIEMLINELKFSNIVLQQENVCITYSTGLPTACVVNMHENSISISCVEEGISIPEGRIKLLYGTSDILCLFHSLLIRIGFPKTAIESYSDYQGVQSIEELFATACELIPSNESKASKLNGNRKSIDPNGRIRCQSIDMYIGSEAIIAGLALFHPSLICKDSPKYQFQHNLADESEPDDPFDDLYLTLTSRDRKKQRLDENGGVAGGAGGISNGNFQQAGDEIDPDEDNGNNHNNSHSNNNSHSNSNYINSANSKLHRISNLIPESPGSCSQNDPNKALPLNDAIVKSINKSLSSLAVVIDNITETSQQLCSVILAGEPIEFPGCVELLENSLKPSLSQCGEVEVIHNDFTDGISAHSAAWKGASMITLVGYCDDLWISGKDWNKYGSRAIREKAPFLW 602          
The following BLAST results are available for this feature:
BLAST of Actin-related protein 8 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 3
Match NameE-valueIdentityDescription
ACTR84.898e-4230.62actin related protein 8 [Source:HGNC Symbol;Acc:HG... [more]
ACTR82.246e-3432.51actin related protein 8 [Source:HGNC Symbol;Acc:HG... [more]
ACTR82.197e-1939.81actin related protein 8 [Source:HGNC Symbol;Acc:HG... [more]
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BLAST of Actin-related protein 8 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Actin-related protein 8 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 1
Match NameE-valueIdentityDescription
Arp85.827e-4727.13gene:FBgn0030877 transcript:FBtr0074544[more]
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BLAST of Actin-related protein 8 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 1
Match NameE-valueIdentityDescription
actr81.239e-4029.38actin related protein 8 [Source:NCBI gene;Acc:3268... [more]
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BLAST of Actin-related protein 8 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 1
Match NameE-valueIdentityDescription
edn11.649e-2539.71endothelin 1 [Source:Xenbase;Acc:XB-GENE-491328][more]
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BLAST of Actin-related protein 8 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 2
Match NameE-valueIdentityDescription
Actr81.143e-4827.55ARP8 actin-related protein 8 [Source:MGI Symbol;Ac... [more]
Actr81.143e-4827.55ARP8 actin-related protein 8 [Source:MGI Symbol;Ac... [more]
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BLAST of Actin-related protein 8 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|Q1LZF2|ARP8_BOVIN5.287e-4927.59Actin-related protein 8 OS=Bos taurus OX=9913 GN=A... [more]
sp|D2I1E3|ARP8_AILME5.509e-4827.59Actin-related protein 8 OS=Ailuropoda melanoleuca ... [more]
sp|Q8R2S9|ARP8_MOUSE7.993e-4827.55Actin-related protein 8 OS=Mus musculus OX=10090 G... [more]
sp|Q29G73|ARP8_DROPS1.761e-4725.36Actin-related protein 8 OS=Drosophila pseudoobscur... [more]
sp|Q9VX09|ARP8_DROME5.841e-4627.13Actin-related protein 8 OS=Drosophila melanogaster... [more]
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BLAST of Actin-related protein 8 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
A0A4W4DUC22.491e-5328.03Actin-related protein 8 OS=Electrophorus electricu... [more]
A0A3B4BZE13.059e-5126.61Actin-related protein 8 OS=Pygocentrus nattereri O... [more]
A0A3B3QV609.388e-5127.83Actin-related protein 8 OS=Paramormyrops kingsleya... [more]
A0A5K4F5T91.543e-5031.90Uncharacterized protein OS=Schistosoma mansoni OX=... [more]
A0A2D0R2P32.028e-5026.44Actin-related protein 8 OS=Ictalurus punctatus OX=... [more]
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BLAST of Actin-related protein 8 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 3
Match NameE-valueIdentityDescription
actr81.864e-5327.64actin related protein 8 [Source:NCBI gene;Acc:1030... [more]
actr81.760e-4126.20actin related protein 8 [Source:NCBI gene;Acc:1030... [more]
actr84.415e-4032.09actin related protein 8 [Source:NCBI gene;Acc:1030... [more]
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BLAST of Actin-related protein 8 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 1
Match NameE-valueIdentityDescription
actr82.940e-2525.19actin related protein 8 [Source:NCBI gene;Acc:3268... [more]
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BLAST of Actin-related protein 8 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 1
Match NameE-valueIdentityDescription
ARP87.194e-1823.24Nuclear actin-related protein involved in chromati... [more]
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BLAST of Actin-related protein 8 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 1
Match NameE-valueIdentityDescription
EDO479305.001e-3228.02Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
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BLAST of Actin-related protein 8 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 2
Match NameE-valueIdentityDescription
actr85.057e-4129.46actin related protein 8 [Source:NCBI gene;Acc:1011... [more]
actr81.168e-3828.74actin related protein 8 [Source:NCBI gene;Acc:1011... [more]
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BLAST of Actin-related protein 8 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 1
Match NameE-valueIdentityDescription
SMESG000050181.10.000e+0100.00SMESG000050181.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30013599 ID=SMED30013599|Name=Actin-related protein 8|organism=Schmidtea mediterranea sexual|type=transcript|length=2449bp
ATATAAATCTTATATGAAATGGAAAGATAAATATTTTATTTGAAATCTAA
AATGTCTAAAATTACATCATTTCCAAGAGAAAATATAATTGTTATTCATC
CATCGGCTACAAAATTACGATTTGGTCGGAGTAATGATTCAGAACCAATA
ATAATTCCCCACTGTATAGCTCGGAAATGCAAAATTATTTCTAAAGTTAT
AAGACAACCCAAAATTCCAGATAATCGGGCTAGTACATTATTAAATACTA
AATTTAACAATGCCATCAAGCTGGCTTCAATTGCTATGAAGTCTTCTTCA
ATCGAAGTCCTTCAACCATTCAAAGAACAACCAACGATAAATGAATTAAT
CCACATGAATAAACAATATTTAAAATTGGATTCTCTGTCCGATATCTCCA
GCATTCATCGAGTGTATTCTGAAGAATTTTACATCGGTAAAGAGGCACTA
GAAGTGCCCATCGAAGCTAATTACAATTTACATTGGCCATTTTGGGATGA
TAAAATTTCGGATAAATATTCCAAAACTGCTGCAGTGAAAGATCTCGAAG
ATATCTGGCGAATGGGAATTGAAAAGTCATTGAAAATTCCCTCAGAAGAT
TTAGCGAACTATCGAATTATTCTTGTGATTTCCGATTTGATAATTCGAAG
TGAAATTCGATGGATAATTGAAATGCTAATAAACGAGTTGAAATTCAGTA
ATATTGTGTTGCAACAAGAAAACGTCTGCATCACATACAGCACAGGATTG
CCAACAGCATGCGTTGTGAACATGCACGAAAATTCTATTTCCATTTCCTG
TGTCGAAGAGGGCATCTCGATTCCGGAAGGTCGAATTAAACTTTTATACG
GAACCAGCGACATTCTCTGTTTGTTCCATTCGCTATTGATTCGGATCGGA
TTTCCGAAGACCGCCATTGAATCGTATAGCGACTACCAGGGAGTGCAATC
GATCGAGGAGTTGTTTGCAACGGCTTGCGAACTTATCCCGTCTAACGAAT
CAAAAGCCAGCAAATTAAATGGCAACCGGAAATCGATCGATCCAAACGGC
CGGATCCGCTGTCAATCGATTGATATGTACATCGGATCTGAGGCGATAAT
TGCTGGACTCGCATTATTCCATCCATCCCTCATTTGTAAGGACTCGCCAA
AATATCAATTCCAGCACAATCTCGCCGACGAATCCGAGCCCGATGATCCG
TTCGATGATCTCTACTTGACTTTGACGTCACGGGATCGGAAAAAACAACG
ATTGGATGAAAATGGCGGGGTCGCTGGTGGAGCGGGGGGCATATCGAATG
GGAATTTCCAACAGGCCGGCGATGAAATCGATCCGGACGAGGATAACGGC
AATAATCACAACAATAGCCATAGCAACAATAACAGCCATAGCAACAGTAA
CTACATCAACAGTGCCAACTCAAAACTCCATCGAATCTCGAATCTGATTC
CAGAATCACCTGGCAGCTGCTCCCAGAACGACCCTAACAAAGCGTTACCA
CTCAATGACGCAATCGTCAAATCGATTAATAAATCTCTCAGTTCATTAGC
GGTTGTCATTGACAACATCACTGAGACAAGCCAGCAACTATGCAGTGTGA
TCCTGGCCGGTGAGCCTATCGAGTTCCCCGGCTGCGTTGAGTTGCTTGAG
AATTCCCTCAAACCGAGTCTCTCCCAGTGCGGGGAAGTTGAGGTGATCCA
CAACGATTTCACCGATGGGATTTCCGCGCACAGTGCGGCTTGGAAGGGGG
CCTCGATGATCACGCTAGTTGGCTACTGTGACGATTTGTGGATCAGTGGT
AAGGATTGGAACAAATACGGGTCGAGGGCCATTCGGGAGAAGGCACCATT
TCTGTGGTGACGTCCAATGTTAAAGTTTTTTTGTTTACCACTCAATATAT
ATGTTTTCTCGTCTTTCGGTTTCCGATTGTGTCGTTTCACAAGATCATCT
CATTCGCCCTCACTCTTTATCTTGATTGAGGATTCGGCTTATTTATCTCT
GTTCTGTTTTGTTTCATCACTAGGTTACCATTTCATTTCTTCACTTGAAT
TACTTTATTAGGTCATTGGATTGTAAAGAGCATCACGTTACCAAGTCAAT
TTGTCCAAATATTTTTAGTTTTAACCATTTCGTTATTTACGGTAACAAGA
TTAAAATTCAATGTGATAATACGGGATTTCATTTTGATTATGGCCTTTAA
ATGTTTTGATACCCTTTTGAAAATGTTTAACATTTCTTTATAAAATAAAT
TACATCGATTTCAAGATAAATTATTTAAATTAAAAAACCATACAAAAAAT
TTACATACATACAAAAAATTTTTTGAATGAGTTACACATTAGTTATTACT
TGCATTATCTGACGGGAAAAAATTTATCTCCGTATCCACTTTCAAGAGGG
TTGTAATCAGTTACGGGCATAAGAAAAGTTTACACGTTAAGCACAGATC
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protein sequence of SMED30013599-orf-1

>SMED30013599-orf-1 ID=SMED30013599-orf-1|Name=SMED30013599-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=603bp
MSKITSFPRENIIVIHPSATKLRFGRSNDSEPIIIPHCIARKCKIISKVI
RQPKIPDNRASTLLNTKFNNAIKLASIAMKSSSIEVLQPFKEQPTINELI
HMNKQYLKLDSLSDISSIHRVYSEEFYIGKEALEVPIEANYNLHWPFWDD
KISDKYSKTAAVKDLEDIWRMGIEKSLKIPSEDLANYRIILVISDLIIRS
EIRWIIEMLINELKFSNIVLQQENVCITYSTGLPTACVVNMHENSISISC
VEEGISIPEGRIKLLYGTSDILCLFHSLLIRIGFPKTAIESYSDYQGVQS
IEELFATACELIPSNESKASKLNGNRKSIDPNGRIRCQSIDMYIGSEAII
AGLALFHPSLICKDSPKYQFQHNLADESEPDDPFDDLYLTLTSRDRKKQR
LDENGGVAGGAGGISNGNFQQAGDEIDPDEDNGNNHNNSHSNNNSHSNSN
YINSANSKLHRISNLIPESPGSCSQNDPNKALPLNDAIVKSINKSLSSLA
VVIDNITETSQQLCSVILAGEPIEFPGCVELLENSLKPSLSQCGEVEVIH
NDFTDGISAHSAAWKGASMITLVGYCDDLWISGKDWNKYGSRAIREKAPF
LW*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: molecular function
TermDefinition
GO:0000166nucleotide binding
GO:0005524ATP binding
Vocabulary: cellular component
TermDefinition
GO:0005634nucleus
GO:0031011Ino80 complex
Vocabulary: biological process
TermDefinition
GO:0006281DNA repair
GO:0006310DNA recombination
GO:0006974cellular response to DNA damage stimulus
GO:0006338chromatin remodeling
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000034epidermis
PLANA:0000418head
Vocabulary: INTERPRO
TermDefinition
IPR027668Arp8/plant_Arp9
IPR043129ATPase_NBD
IPR004000Actin
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR004000Actin familySMARTSM00268actin_3coord: 10..599
e-value: 9.6E-6
score: -79.3
IPR004000Actin familyPFAMPF00022Actincoord: 125..296
e-value: 3.3E-8
score: 32.6
coord: 511..597
e-value: 2.6E-5
score: 23.0
IPR004000Actin familyPANTHERPTHR11937ACTINcoord: 12..597
NoneNo IPR availableGENE3DG3DSA:3.30.420.40coord: 7..98
e-value: 2.1E-6
score: 29.4
NoneNo IPR availableGENE3DG3DSA:3.30.420.40coord: 433..597
e-value: 9.4E-11
score: 43.5
coord: 105..249
e-value: 8.0E-23
score: 82.8
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 395..417
IPR027668Actin-related protein 8/Plant actin-related protein 9PANTHERPTHR11937:SF13ACTIN-RELATED PROTEIN 8coord: 12..597
IPR043129ATPase, nucleotide binding domainSUPERFAMILYSSF53067Actin-like ATPase domaincoord: 234..597
IPR043129ATPase, nucleotide binding domainSUPERFAMILYSSF53067Actin-like ATPase domaincoord: 10..239