Ribosomal RNA large subunit methyltransferase E

Overview


Name	Ribosomal RNA large subunit methyltransferase E
Smed ID	SMED30013594
Length (bp)	901

Neoblast Clusters

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Overview

Single cell RNA-seq of pluripotent neoblasts and its early progenies

We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)

Explore this single cell expression dataset with our NB Cluster Shiny App

Neoblast Population

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.

Expression of Ribosomal RNA large subunit methyltransferase E (SMED30013594) t-SNE clustered cells

Violin plots show distribution of expression levels for Ribosomal RNA large subunit methyltransferase E (SMED30013594) in cells (dots) of each of the 12 neoblast clusters.

Sub-lethal Irradiated Surviving X1 and X2 Cell Population

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of Ribosomal RNA large subunit methyltransferase E (SMED30013594) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

Anatomical Expression

PAGE et. al., 2020

SMED30013594

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE

PAGE Curations: 1

Expressed In	Reference Transcript	Gene Models	Published Transcript	Transcriptome	Publication	Specimen	Lifecycle	Evidence
X1 cell	SMED30013594	SMESG000015492.1	SmedASXL_010357	SmedAsxl_ww_GCZZ01	PMID:26114597 Zhu et al., 2015

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Homology

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BLAST of Ribosomal RNA large subunit methyltransferase E vs. Ensembl Human
Match: MRM2 (mitochondrial rRNA methyltransferase 2 [Source:HGNC Symbol;Acc:HGNC:16352])

HSP 1 Score: 157.918 bits (398), Expect = 2.386e-46
Identity = 80/207 (38.65%), Postives = 127/207 (61.35%), Query Frame = 2

Query:  119 GADSNVWLSRQLSDPYVKRSRIESFRCRSAFKLIELDNKYKLLYPGITVLDCGAAPGSWSQVISRKCFVTNSASS----LAIAIDKNFFQPIEHIICLSECDINSDSTISLMKEKLGTRKFNLVLSDMAPNASGIKDIDKHTMNQLNQMALKVAIENSCKGASFLFKMWSDMNSEKHLKDLILRFYKSVKIVKPPASRSDSSEIFLL 727
            GA+ ++WL+R L DP+VK +++ES+RCRSAFKL+E++ ++++L PG+ VLDCGAAPG+WSQV  +K     +  S      + +D     P+E    L   D+    T   + E L  R+ +++LSDMAPNA+G +D+D   +  L    L V  +    G +FL K W+   S + L+  +   +++V+I+KP ASR +SSE++ L
Sbjct:   29 GAE-HLWLTRHLRDPFVKAAKVESYRCRSAFKLLEVNERHQILRPGLRVLDCGAAPGAWSQVAVQKVNAAGTDPSSPVGFVLGVDLLHIFPLEGATFLCPADVTDPRTSQRILEVLPGRRADVILSDMAPNATGFRDLDHDRLISLCLTLLSVTPDILQPGGTFLCKTWAGSQSRR-LQRRLTEEFQNVRIIKPEASRKESSEVYFL 233

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Query:  119 GADSNVWLSRQLSDPYVKRSRIESFRCRSAFKLIELDNKYKLLYPGITVLDCGAAPGSWSQVISRKCFVTNSASS----LAIAIDKNFFQPIEHIICLSECDINSDSTISLMKEKLGTRKFNLVLSDMAPNASGIKDIDKHTMNQLNQMALKVAIENSCKGASFLFKMWSDMNSEKHLKDLILRFYKSVKIVKPPASRSDSSEIFLL 727
            GA+ ++WL+R L DP+VK +++ES+RCRSAFKL+E++ ++++L PG+ VLDCGAAPG+WSQV  +K     +  S      + +D     P+E    L   D+    T   + E L  R+ +++LSDMAPNA+G +D+D   +  L    L V  +    G +FL K W+   S + L+  +   +++V+I+KP ASR +SSE++ L
Sbjct:   29 GAE-HLWLTRHLRDPFVKAAKVESYRCRSAFKLLEVNERHQILRPGLRVLDCGAAPGAWSQVAVQKVNAAGTDPSSPVGFVLGVDLLHIFPLEGATFLCPADVTDPRTSQRILEVLPGRRADVILSDMAPNATGFRDLDHDRLISLCLTLLSVTPDILQPGGTFLCKTWAGSQSRR-LQRRLTEEFQNVRIIKPEASRKESSEVYFL 233

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BLAST of Ribosomal RNA large subunit methyltransferase E vs. Ensembl Human
Match: FTSJ3 (FtsJ RNA 2'-O-methyltransferase 3 [Source:HGNC Symbol;Acc:HGNC:17136])

HSP 1 Score: 107.457 bits (267), Expect = 2.454e-25
Identity = 67/207 (32.37%), Postives = 117/207 (56.52%), Query Frame = 2

Query:  119 GADSNVWLSRQLSDPYVKRSRIESFRCRSAFKLIELDNKYKLLYPGITVLDCGAAPGSWSQVISRKCFVTNSASSLAIAIDKNFFQPIEHIICLSECDINSDSTISLMKEKLGTRKFNLVLSDMAPNASGIKDIDKHTMNQLNQMALKVAIENSCKGASFLFKMWSDMNSEKHLKDLILRFYKSVKIVKPPASRSDSSEIFLLCQGF 739
            G    V  SR+  D +   ++   +R RSAFKLI+L+ +++ L     +LD  AAPG W QV ++   V    SSL + +D    +P+ +++ L + DI ++     ++++L T K ++VL+D APN       D ++   L  MAL++A +   +G SF+ K++   + +  L  +  + ++ V+  KP ASR +S+EIF++CQGF
Sbjct:    2 GKKGKVGKSRR--DKFYHLAKETGYRSRSAFKLIQLNRRFQFLQKARALLDLCAAPGGWLQVAAKFMPV----SSLIVGVDLVPIKPLPNVVTLQQ-DITTERCRQALRKELKTWKVDVVLNDGAPNVGASWVHDAYSQAHLTLMALRLACDFLARGGSFITKVFRSRDYQPLLW-IFQQLFRRVQATKPQASRHESAEIFVVCQGF 200

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BLAST of Ribosomal RNA large subunit methyltransferase E vs. Ensembl Human
Match: FTSJ1 (FtsJ RNA 2'-O-methyltransferase 1 [Source:HGNC Symbol;Acc:HGNC:13254])

HSP 1 Score: 101.293 bits (251), Expect = 4.172e-24
Identity = 63/199 (31.66%), Postives = 105/199 (52.76%), Query Frame = 2

Query:  143 SRQLSDPYVKRSRIESFRCRSAFKLIELDNKYKLLYPGITVLDCGAAPGSWSQVISRKCFVTNSASSLAIAIDKNFFQPIEHIICLSECDINSDSTISLMKEKLGTRKFNLVLSDMAPNASGIKDIDKHTMNQLNQMALKVAIENSCKGASFLFKMWSDMNSEKHLKDLILRFYKSVKIVKPPASRSDSSEIFLLCQGF 739
            S+   D Y + ++   +R RSAFKL++LD +++L       +D  AAPGSWSQV+S+K  +    S   +A+D     P+  ++ + + DI   ST   + +       +LV+ D AP+ +G+ D+D++   QL   AL +A      G  F+ K++   +       L + F+ SV   KP +SR+ S E F +CQG+
Sbjct:    5 SKDKRDVYYRLAKENGWRARSAFKLLQLDKEFQLFQGVTRAVDLCAAPGSWSQVLSQK--IGGQGSGHVVAVDLQAMAPLPGVVQI-QGDITQLSTAKEIIQHFKGCPADLVVCDGAPDVTGLHDVDEYMQAQLLLAALNIATHVLKPGGCFVAKIFRGRDVTLLYSQLQV-FFSSVLCAKPRSSRNSSIEAFAVCQGY 199

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BLAST of Ribosomal RNA large subunit methyltransferase E vs. Ensembl Human
Match: FTSJ1 (FtsJ RNA 2'-O-methyltransferase 1 [Source:HGNC Symbol;Acc:HGNC:13254])

HSP 1 Score: 101.293 bits (251), Expect = 4.431e-24
Identity = 65/200 (32.50%), Postives = 109/200 (54.50%), Query Frame = 2

Query:  143 SRQLSDPYVKRSRIESFRCRSAFKLIELDNKYKLLYPGIT-VLDCGAAPGSWSQVISRKCFVTNSASSLAIAIDKNFFQPIEHIICLSECDINSDSTISLMKEKLGTRKFNLVLSDMAPNASGIKDIDKHTMNQLNQMALKVAIENSCKGASFLFKMWSDMNSEKHLKDLILRFYKSVKIVKPPASRSDSSEIFLLCQGF 739
            S+   D Y + ++   +R RSAFKL++LD +++L + G+T  +D  AAPGSWSQV+S+K  +    S   +A+D     P+  ++ + + DI   ST   + +       +LV+ D AP+ +G+ D+D++   QL   AL +A      G  F+ K++   +       L + F+ SV   KP +SR+ S E F +CQG+
Sbjct:    5 SKDKRDVYYRLAKENGWRARSAFKLLQLDKEFQL-FQGVTRAVDLCAAPGSWSQVLSQK--IGGQGSGHVVAVDLQAMAPLPGVVQI-QGDITQLSTAKEIIQHFKGCPADLVVCDGAPDVTGLHDVDEYMQAQLLLAALNIATHVLKPGGCFVAKIFRGRDVTLLYSQLQV-FFSSVLCAKPRSSRNSSIEAFAVCQGY 199

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BLAST of Ribosomal RNA large subunit methyltransferase E vs. Ensembl Celegans
Match: F45G2.9 (rRNA methyltransferase 2, mitochondrial [Source:UniProtKB/Swiss-Prot;Acc:O62251])

HSP 1 Score: 128.642 bits (322), Expect = 7.684e-36
Identity = 77/217 (35.48%), Postives = 122/217 (56.22%), Query Frame = 2

Query:  107 FFSKGADSNV--WLSRQLSDPYVKRSRIESFRCRSAFKLIELDNKYKLLYPGITVLDCGAAPGSWSQVISRKCFVTNSASSLAIAIDKNFFQPIEHIICLSECDINSDSTISLMKEKLGTRKFNLVLSDMAPNASGIKDIDKHTMNQLNQMALKV-AIENS---CKGASFLFKMWSDMNSEKHLKDLILRFYKSVKIVKPPASRSDSSEIFLLCQGF 739
            F +K +  N+  ++ RQ +D +  ++R  ++R RSAFKLIE++ K+K L P  TV+D G APGSW QV+ +KC      +  A  +D     PI     LS  DI   +    ++EKL  R+ ++VLSDMAPN +G    D   + +L +   ++ ++EN     K   +L K+W      + +++L  RF  +VK VKP A R +S+E++L C+ F
Sbjct:    2 FSTKKSQGNLHKYIQRQSTDEFAVKAREHNYRARSAFKLIEINEKFKFLKPESTVIDIGCAPGSWLQVVVQKC-----PNGYASGVDLQNVLPIRGADILSLSDITDPAVKLKIREKLAHRQVDVVLSDMAPNPTGDNATDHLRLIELCRSVFRLFSVENEIELVKNGVYLCKIWDGSARAEFVRELSDRF-STVKTVKPTACRDNSAELYLFCRNF 212

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BLAST of Ribosomal RNA large subunit methyltransferase E vs. Ensembl Celegans
Match: R74.7 (Putative tRNA (cytidine(32)/guanosine(34)-2'-O)-methyltransferase [Source:UniProtKB/Swiss-Prot;Acc:Q22031])

HSP 1 Score: 100.523 bits (249), Expect = 2.757e-24
Identity = 63/196 (32.14%), Postives = 109/196 (55.61%), Query Frame = 2

Query:  143 SRQLSDPYVKRSRIESFRCRSAFKLIELDNKYKLLYPGITVLDCGAAPGSWSQVISRKCFVTNSASSLAIAIDKNFFQPIEHIICLSECDINSDSTISLMKEKLGTRKFNLVLSDMAPNASGIKDIDKHTMNQLNQMALKVAIENSCKGASFLFKMWSDMNSEKHLKDLILRFYKSVKIVKPPASRSDSSEIFLLC 730
            SR   D Y + ++   +R RSAFKL+++D+++++L      +D  AAPGSWSQV+S++ +  +  + + +AID     PI  +I L + DI S  T + + +     K ++V+ D AP+ +GI  +D+    +L   A  +      +G +FL K++   NS   L   + +++K V + KP +SR  S E F+LC
Sbjct:    5 SRDKRDIYYRLAKENKWRARSAFKLMQIDDEFQILKGVRRAVDLCAAPGSWSQVLSKRLYEEDQEAKI-VAIDLQPMAPIPGVIQL-QGDITSVDTANQVIKHFSGEKSDIVICDGAPDVTGIHSLDEFMQAELILAAFNITSHVLKEGGNFLAKIFRSRNSS-LLYAQMKKYFKKVYLAKPRSSRQSSCEAFVLC 197

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BLAST of Ribosomal RNA large subunit methyltransferase E vs. Ensembl Celegans
Match: H06I04.3 (rRNA methyltransferase [Source:UniProtKB/TrEMBL;Acc:Q5CCJ3])

HSP 1 Score: 96.6709 bits (239), Expect = 3.928e-22
Identity = 69/201 (34.33%), Postives = 113/201 (56.22%), Query Frame = 2

Query:  134 VWLSRQLSDPYVKRSRIESFRCRSAFKLIELDNKYKLLYPGITVLDCGAAPGSWSQVISRKCFVTNSASSLAIAIDKNFFQPIEHIICLSECDINSDSTISLMKEKLGTRKFNLVLSDMAPNASGIKDI-DKHTMNQLNQMALKVAIENSCKGASFLFKMWSDMNSEKHLKDLILRFYKSVKIVKPPASRSDSSEIFLLCQ 733
            V + +Q  D Y K ++   +R R+AFKL++L+ +++ L      +D  AAPG W QV S+   V    SSL + +D    +PI++ I L + DI ++ T + +K++L T   + VL D APN  G+  + D    N L   ALK+A +   KG +F+ K++   N    L  +  + +K V + KP ASR +S+EIF++C+
Sbjct:    5 VKIGKQRRDKYYKLAKEAGYRSRAAFKLVQLNKRFEFLEKSRATVDLCAAPGGWMQVASQFMPV----SSLIVGVDLAPIKPIKNCIAL-QGDITTNETRAAIKKELKTWSADCVLHDGAPNV-GLNWVHDAFQQNCLTLSALKLATQILRKGGTFVTKVFR-SNDYSCLIRVFEKLFKRVHVWKPAASRLESAEIFVVCE 198

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BLAST of Ribosomal RNA large subunit methyltransferase E vs. Ensembl Celegans
Match: H06I04.3 (rRNA methyltransferase [Source:UniProtKB/TrEMBL;Acc:Q5CCJ3])

HSP 1 Score: 95.9005 bits (237), Expect = 7.307e-22
Identity = 69/201 (34.33%), Postives = 113/201 (56.22%), Query Frame = 2

Query:  134 VWLSRQLSDPYVKRSRIESFRCRSAFKLIELDNKYKLLYPGITVLDCGAAPGSWSQVISRKCFVTNSASSLAIAIDKNFFQPIEHIICLSECDINSDSTISLMKEKLGTRKFNLVLSDMAPNASGIKDI-DKHTMNQLNQMALKVAIENSCKGASFLFKMWSDMNSEKHLKDLILRFYKSVKIVKPPASRSDSSEIFLLCQ 733
            V + +Q  D Y K ++   +R R+AFKL++L+ +++ L      +D  AAPG W QV S+   V    SSL + +D    +PI++ I L + DI ++ T + +K++L T   + VL D APN  G+  + D    N L   ALK+A +   KG +F+ K++   N    L  +  + +K V + KP ASR +S+EIF++C+
Sbjct:    5 VKIGKQRRDKYYKLAKEAGYRSRAAFKLVQLNKRFEFLEKSRATVDLCAAPGGWMQVASQFMPV----SSLIVGVDLAPIKPIKNCIAL-QGDITTNETRAAIKKELKTWSADCVLHDGAPNV-GLNWVHDAFQQNCLTLSALKLATQILRKGGTFVTKVFR-SNDYSCLIRVFEKLFKRVHVWKPAASRLESAEIFVVCE 198

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BLAST of Ribosomal RNA large subunit methyltransferase E vs. Ensembl Celegans
Match: H06I04.3 (rRNA methyltransferase [Source:UniProtKB/TrEMBL;Acc:Q5CCJ3])

HSP 1 Score: 95.9005 bits (237), Expect = 8.674e-22
Identity = 69/201 (34.33%), Postives = 113/201 (56.22%), Query Frame = 2

Query:  134 VWLSRQLSDPYVKRSRIESFRCRSAFKLIELDNKYKLLYPGITVLDCGAAPGSWSQVISRKCFVTNSASSLAIAIDKNFFQPIEHIICLSECDINSDSTISLMKEKLGTRKFNLVLSDMAPNASGIKDI-DKHTMNQLNQMALKVAIENSCKGASFLFKMWSDMNSEKHLKDLILRFYKSVKIVKPPASRSDSSEIFLLCQ 733
            V + +Q  D Y K ++   +R R+AFKL++L+ +++ L      +D  AAPG W QV S+   V    SSL + +D    +PI++ I L + DI ++ T + +K++L T   + VL D APN  G+  + D    N L   ALK+A +   KG +F+ K++   N    L  +  + +K V + KP ASR +S+EIF++C+
Sbjct:    5 VKIGKQRRDKYYKLAKEAGYRSRAAFKLVQLNKRFEFLEKSRATVDLCAAPGGWMQVASQFMPV----SSLIVGVDLAPIKPIKNCIAL-QGDITTNETRAAIKKELKTWSADCVLHDGAPNV-GLNWVHDAFQQNCLTLSALKLATQILRKGGTFVTKVFR-SNDYSCLIRVFEKLFKRVHVWKPAASRLESAEIFVVCE 198

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BLAST of Ribosomal RNA large subunit methyltransferase E vs. Ensembl Fly
Match: CG11447 (gene:FBgn0038737 transcript:FBtr0083815)

HSP 1 Score: 172.17 bits (435), Expect = 3.365e-52
Identity = 91/235 (38.72%), Postives = 135/235 (57.45%), Query Frame = 2

Query:   50 FCYIMFDYLKCKYVSKLARFF-SKGADSNVWLSRQLSDPYVKRSRIESFRCRSAFKLIELDNKYKLLYPGITVLDCGAAPGSWSQVISRKCFVTN----SASSLAIAIDKNFFQPIEHIICLSECDINSDSTISLMKEKLGTRKFNLVLSDMAPNASGIKDIDKHTMNQLNQMALKVAIENSCKGASFLFKMWSDMNSEKHLKDLILRFYKSVKIVKPPASRSDSSEIFLLCQGF 739
            F  ++   +  KY  +  R    +   S  WL+RQL+DPYV+++R+ ++RCRSAFKL+E+D+KY +L PG TVL+CGAAPGSW+QV   +         +      +ID   F  +         D  S      ++E L  RK N VLSDMAPNA+G++ +D+ ++  L    L+ A+  S   A  + K+W + +  K  +D+ LRFY+ VK VKP ASR DS+E FL+ + F
Sbjct:   11 FKRLLHTEIGGKYAKQQPRNLKGRSKSSQEWLTRQLADPYVEKARMMNYRCRSAFKLLEIDDKYGILRPGDTVLECGAAPGSWTQVAVERTNANGKQERAPQGAVFSIDLLHFHAVPGATIFGGMDFTSSLAQKRLREALQDRKVNCVLSDMAPNATGVRMLDQESITNLCYEVLRFALAMSAPQAHLVVKVWDNGDVPKLERDM-LRFYEKVKRVKPRASRGDSAEHFLVARNF 244

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BLAST of Ribosomal RNA large subunit methyltransferase E vs. Ensembl Fly
Match: CG5220 (gene:FBgn0038471 transcript:FBtr0083391)

HSP 1 Score: 110.153 bits (274), Expect = 7.377e-28
Identity = 72/205 (35.12%), Postives = 112/205 (54.63%), Query Frame = 2

Query:  143 SRQLSDPYVKRSRIESFRCRSAFKLIELDNKYKLLYPGITVLDCGAAPGSWSQVISRK----CFVTNSASSLA-IAIDKNFFQPIEHIICLSECDINSDSTI-SLMKEKLGTRKFNLVLSDMAPNASGIKDIDKHTMNQLNQMALKVAIENSCKGASFLFKMWSDMNSEKHLKDLILRFYKSVKIVKPPASRSDSSEIFLLCQGF 739
            S+   D Y ++++ E +R RSAFKL+ +D  Y +L      +D  AAPGSWSQV+SRK    C   +  S++  IA+D     PI  I+ L + DI   ST  +++    G  K  LV+ D AP+ +G+ ++D++  +QL   AL +A      G +F+ K++   N+   L   +  F+K   I KPP+SR  S E F++C  F
Sbjct:    5 SKDKRDIYYRQAKDEGWRARSAFKLLHVDEAYGILNGVQRAVDLCAAPGSWSQVLSRKLYDTCETDDEKSAVKIIAVDLQAMAPIRGILQL-QGDITKQSTAEAIIGHFGGNEKAQLVVCDGAPDVTGVHEMDEYMQHQLLVAALSIATCVLETGGTFVAKIFKG-NATSLLSSQMQIFFKKFDIYKPPSSRPSSIEAFVVCSDF 207

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BLAST of Ribosomal RNA large subunit methyltransferase E vs. Ensembl Fly
Match: CG7009 (gene:FBgn0038861 transcript:FBtr0084029)

HSP 1 Score: 103.99 bits (258), Expect = 1.919e-25
Identity = 67/204 (32.84%), Postives = 112/204 (54.90%), Query Frame = 2

Query:  143 SRQLSDPYVKRSRIESFRCRSAFKLIELDNKYKLLYPGITVLDCGAAPGSWSQVISRKCFVTNSASSLA----IAIDKNFFQPIEHIICLSECDINSDSTISLMKEKLGTRKFNLVLSDMAPNASGIKDIDKHTMNQLNQMALKVAIENSCKGASFLFKMW-SDMNSEKHLKDLILRFYKSVKIVKPPASRSDSSEIFLLCQGF 739
            S+   D + + ++ + +R RSAFKL++ D  ++LL      +D  AAPGSWSQV++++ +             IA+D     PIE +  L   DI+ +ST   + E  G  K  +V+SD AP+++G+ D D +   +L   AL ++     +G SF+ K++ +D  S   L   + RF+K+V + KP ASR+ S E F++ + F
Sbjct:    5 SKDKRDIFYRLAKEQGWRARSAFKLLQADETFQLLEGLTRAVDLCAAPGSWSQVLAKRLYEPLPPEEREKVKIIAVDLQGMAPIEGVKQL-RADISKESTAEAIIEFFGGEKAQIVVSDGAPDSTGMHDFDSYVQGELLLSALSISTFILEEGGSFVSKIYRADRTS--RLYTQLKRFFKNVCVFKPSASRNSSIEAFVVAREF 205

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BLAST of Ribosomal RNA large subunit methyltransferase E vs. Ensembl Fly
Match: CG8939 (gene:FBgn0030720 transcript:FBtr0074138)

HSP 1 Score: 83.5741 bits (205), Expect = 1.252e-17
Identity = 68/209 (32.54%), Postives = 108/209 (51.67%), Query Frame = 2

Query:  119 GADSNVWLSRQLSDPYVKRSRIESFRCRSAFKLIELDNKYKLLYPGITVLDCGAAPGSWSQVISRKCFVTNSASSLAIAIDKNFFQPIEHIICLSECDINSDSTISLMKEKLGTRKFNLVLSDMAPNASGIKDIDKHTMNQLNQMALKVAIENSCKGASFLFKMW--SDMNSEKHLKDLILRFYKSVKIVKPPASRSDSSEIFLLCQGF 739
            G  + V  +R+  D + + ++    R R+AFKLI+L+ K+  L      LD  AAPG W QV  +   V    SS+ I +D    +PI   I L E DI ++     + ++L + K ++VL D APN       D +    L   ALK++ +    G  F+ K++   D N+   L  ++ + +K V   KP ASR +S+EIF++CQG+
Sbjct:    2 GKKTKVGKTRK--DKFYQLAKETGLRSRAAFKLIQLNRKFGFLQQSQVCLDLCAAPGGWMQVAKQNMPV----SSIVIGVDLFPIRPIAGCIGLVE-DITTEKCRQSLTKELQSWKADVVLHDGAPNVGRNWLYDAYQQICLTLNALKLSTQFLRNGGWFVTKVFRSKDYNA---LLWVLKQLFKKVHATKPSASRKESAEIFVVCQGY 200

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BLAST of Ribosomal RNA large subunit methyltransferase E vs. Ensembl Zebrafish
Match: mrm2 (mitochondrial rRNA methyltransferase 2 [Source:ZFIN;Acc:ZDB-GENE-030131-5205])

HSP 1 Score: 152.525 bits (384), Expect = 2.771e-44
Identity = 83/203 (40.89%), Postives = 122/203 (60.10%), Query Frame = 2

Query:  137 WLSRQLSDPYVKRSRIESFRCRSAFKLIELDNKYKLLYPGITVLDCGAAPGSWSQVISRKCFVTNSASSL----AIAIDKNFFQPIEHIICLSECDINSDSTISLMKEKLGTRKFNLVLSDMAPNASGIKDIDKHTMNQLNQMALKVAIENSCKGASFLFKMWSDMNSEKHLKDLILRFYKSVKIVKPPASRSDSSEIFLLCQ 733
            WL RQLSDP+VK +  +++RCRSAFKLIE+D+KY+LL PG TV+DCGAAPG+WSQV  ++   T  +  L     I ID     P++    L+  DI S ST + ++  L     +++LSDMAPNASG +++D   +  +    L +A +    G S + K W D      L+  +   ++ V+ VKP ASR +S+E+F L +
Sbjct:   53 WLIRQLSDPFVKAAHEQNYRCRSAFKLIEMDDKYRLLKPGFTVIDCGAAPGAWSQVAVQRVNSTGESVDLPKGSVIGIDILHIFPLDGAQFLTNHDITSPSTHTALERLLPEAGADVILSDMAPNASGFRELDHERLVSMCLSMLDLADKVLRPGGSLICKYW-DGGLAHMLQQRLFSAFQDVRTVKPRASRKESAELFFLAR 254

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BLAST of Ribosomal RNA large subunit methyltransferase E vs. Ensembl Zebrafish
Match: ftsj3 (FtsJ RNA 2'-O-methyltransferase 3 [Source:ZFIN;Acc:ZDB-GENE-030131-9828])

HSP 1 Score: 113.62 bits (283), Expect = 1.344e-27
Identity = 69/184 (37.50%), Postives = 109/184 (59.24%), Query Frame = 2

Query:  188 SFRCRSAFKLIELDNKYKLLYPGITVLDCGAAPGSWSQVISRKCFVTNSASSLAIAIDKNFFQPIEHIICLSECDINSDSTISLMKEKLGTRKFNLVLSDMAPNASGIKDIDKHTMNQLNQMALKVAIENSCKGASFLFKMWSDMNSEKHLKDLILRFYKSVKIVKPPASRSDSSEIFLLCQGF 739
             +R RS+FKLI+L+ K++ L     ++D  AAPG W QV S+   V    SSL I +D    +PI +++ L E DI ++     ++++L T K ++VL+D APN       D  +   L  MALK+A E   KG +F+ K++   + +  L  +  +F+K V+  KP ASR++S+EIF++CQGF
Sbjct:   23 GYRSRSSFKLIQLNRKFQFLQKARALVDLCAAPGGWLQVASKFMPV----SSLVIGVDLVPIKPIPNVVTLQE-DITTEKCRQALRKELQTWKVDVVLNDGAPNVGANWQHDAFSQANLTLMALKLACEFLAKGGTFITKVFRSKDYQ-PLMWIFQQFFKKVQATKPQASRNESAEIFVVCQGF 200

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BLAST of Ribosomal RNA large subunit methyltransferase E vs. Ensembl Zebrafish
Match: ftsj3 (FtsJ RNA 2'-O-methyltransferase 3 [Source:ZFIN;Acc:ZDB-GENE-030131-9828])

HSP 1 Score: 113.62 bits (283), Expect = 1.345e-27
Identity = 69/184 (37.50%), Postives = 109/184 (59.24%), Query Frame = 2

Query:  188 SFRCRSAFKLIELDNKYKLLYPGITVLDCGAAPGSWSQVISRKCFVTNSASSLAIAIDKNFFQPIEHIICLSECDINSDSTISLMKEKLGTRKFNLVLSDMAPNASGIKDIDKHTMNQLNQMALKVAIENSCKGASFLFKMWSDMNSEKHLKDLILRFYKSVKIVKPPASRSDSSEIFLLCQGF 739
             +R RS+FKLI+L+ K++ L     ++D  AAPG W QV S+   V    SSL I +D    +PI +++ L E DI ++     ++++L T K ++VL+D APN       D  +   L  MALK+A E   KG +F+ K++   + +  L  +  +F+K V+  KP ASR++S+EIF++CQGF
Sbjct:   23 GYRSRSSFKLIQLNRKFQFLQKARALVDLCAAPGGWLQVASKFMPV----SSLVIGVDLVPIKPIPNVVTLQE-DITTEKCRQALRKELQTWKVDVVLNDGAPNVGANWQHDAFSQANLTLMALKLACEFLAKGGTFITKVFRSKDYQ-PLMWIFQQFFKKVQATKPQASRNESAEIFVVCQGF 200

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BLAST of Ribosomal RNA large subunit methyltransferase E vs. Ensembl Zebrafish
Match: ftsj1 (FtsJ RNA 2'-O-methyltransferase 1 [Source:ZFIN;Acc:ZDB-GENE-041114-83])

HSP 1 Score: 100.908 bits (250), Expect = 2.709e-24
Identity = 64/200 (32.00%), Postives = 105/200 (52.50%), Query Frame = 2

Query:  143 SRQLSDPYVKRSRIESFRCRSAFKLIELDNKYKLLYPGITVLDCGAAPGSWSQVISRKCFVTNSASSLAI-AIDKNFFQPIEHIICLSECDINSDSTISLMKEKLGTRKFNLVLSDMAPNASGIKDIDKHTMNQLNQMALKVAIENSCKGASFLFKMWSDMNSEKHLKDLILRFYKSVKIVKPPASRSDSSEIFLLCQGF 739
            S+   D Y + ++ E +R RSAFKL++LD ++KL       +D  AAPGSWSQV+SRK    + +  + I A+D     P+  +  + + DI   ST   +         +LV+ D AP+ +G+ D+D++   QL   AL +       G +F+ K++   +       L + F+  V   KPP+SR+ S E F++CQ +
Sbjct:    5 SKDKRDIYYRLAKEEGWRARSAFKLLQLDEEFKLFKGVSRAVDLCAAPGSWSQVLSRKLRGKDKSEEVKIVAVDLQAMAPLPGVTQI-QGDITKISTAEEIIRHFEGESADLVVCDGAPDVTGLHDVDEYIQAQLLLAALNITTHVLKPGGNFVAKIFRGKDVTLLYSQLKI-FFSFVTCAKPPSSRNSSIEAFVVCQNY 202

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BLAST of Ribosomal RNA large subunit methyltransferase E vs. Ensembl Zebrafish
Match: ftsj1 (FtsJ RNA 2'-O-methyltransferase 1 [Source:ZFIN;Acc:ZDB-GENE-041114-83])

HSP 1 Score: 100.908 bits (250), Expect = 2.968e-24
Identity = 64/200 (32.00%), Postives = 105/200 (52.50%), Query Frame = 2

Query:  143 SRQLSDPYVKRSRIESFRCRSAFKLIELDNKYKLLYPGITVLDCGAAPGSWSQVISRKCFVTNSASSLAI-AIDKNFFQPIEHIICLSECDINSDSTISLMKEKLGTRKFNLVLSDMAPNASGIKDIDKHTMNQLNQMALKVAIENSCKGASFLFKMWSDMNSEKHLKDLILRFYKSVKIVKPPASRSDSSEIFLLCQGF 739
            S+   D Y + ++ E +R RSAFKL++LD ++KL       +D  AAPGSWSQV+SRK    + +  + I A+D     P+  +  + + DI   ST   +         +LV+ D AP+ +G+ D+D++   QL   AL +       G +F+ K++   +       L + F+  V   KPP+SR+ S E F++CQ +
Sbjct:    5 SKDKRDIYYRLAKEEGWRARSAFKLLQLDEEFKLFKGVSRAVDLCAAPGSWSQVLSRKLRGKDKSEEVKIVAVDLQAMAPLPGVTQI-QGDITKISTAEEIIRHFEGESADLVVCDGAPDVTGLHDVDEYIQAQLLLAALNITTHVLKPGGNFVAKIFRGKDVTLLYSQLKI-FFSFVTCAKPPSSRNSSIEAFVVCQNY 202

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BLAST of Ribosomal RNA large subunit methyltransferase E vs. Ensembl Xenopus
Match: ankrd13c (ankyrin repeat domain 13C [Source:Xenbase;Acc:XB-GENE-5828071])

HSP 1 Score: 154.451 bits (389), Expect = 4.209e-45
Identity = 81/211 (38.39%), Postives = 130/211 (61.61%), Query Frame = 2

Query:  113 SKGADSNVWLSRQLSDPYVKRSRIESFRCRSAFKLIELDNKYKLLYPGITVLDCGAAPGSWSQVISRKC--FVTNSASS--LAIAIDKNFFQPIEHIICLSECDINSDSTISLMKEKLGTRKFNLVLSDMAPNASGIKDIDKHTMNQLNQMALKVAIENSCKGASFLFKMWSDMNSEKHLKDLILRFYKSVKIVKPPASRSDSSEIFLLCQ 733
            S+ A    WL+RQ+ DPYV+ ++  ++RCRSAFKL+E+DNK+ +L PG  V+DCGAAPG+WSQV   K      +SA+S    + +D     P++  + LS  DI    T   +   L + K +++LSDMAPNA+GI+D+D   +  +    L+++      G +FL K+W D +    ++D + + ++ V+ VKP ASR +S+E++LL +
Sbjct:   30 SRTAAEQRWLARQMKDPYVREAQTHNYRCRSAFKLLEIDNKHHILQPGHHVIDCGAAPGAWSQVAVEKVNSLGRDSAASAGFVVGVDLLNIAPLDGAVFLSNSDITDFDTQKKIISVLPSGKADVILSDMAPNATGIRDLDHQRLVNMCLSLLELSERVLLSGGTFLCKVW-DGSEINLVRDRLRQRFQDVRTVKPKASRMESAEVYLLAK 239

[Close]

BLAST of Ribosomal RNA large subunit methyltransferase E vs. Ensembl Xenopus
Match: FTSJ3 (FtsJ RNA 2'-O-methyltransferase 3 [Source:NCBI gene;Acc:100145257])

HSP 1 Score: 109.768 bits (273), Expect = 2.549e-26
Identity = 71/207 (34.30%), Postives = 118/207 (57.00%), Query Frame = 2

Query:  119 GADSNVWLSRQLSDPYVKRSRIESFRCRSAFKLIELDNKYKLLYPGITVLDCGAAPGSWSQVISRKCFVTNSASSLAIAIDKNFFQPIEHIICLSECDINSDSTISLMKEKLGTRKFNLVLSDMAPNASGIKDIDKHTMNQLNQMALKVAIENSCKGASFLFKMWSDMNSEKHLKDLILRFYKSVKIVKPPASRSDSSEIFLLCQGF 739
            G  + V  SR+  D +   ++   +R RSAFKLI+L+ K++ L     ++D  AAPG W QV ++   +    SSL I +D    +PI  ++ L E DI +++    +++ L T K ++VL+D APN       D  +   L+ MAL++A +   +G  F+ K++   + +  L  ++ +F+K V   KP ASRS+S+EIF++CQGF
Sbjct:    2 GKKAKVGKSRK--DKFYHLAKETGYRSRSAFKLIQLNRKFQFLPKARALVDLCAAPGGWLQVAAKFMPI----SSLIIGVDLVPIKPIPKVLTLQE-DITTEACRQTVRKHLQTWKADVVLNDGAPNVGANWTHDAFSQVHLSLMALRLACDCLSRGGWFITKIFRSSDYQSLLW-ILQQFFKKVNSTKPQASRSESAEIFVVCQGF 200

[Close]

BLAST of Ribosomal RNA large subunit methyltransferase E vs. Ensembl Xenopus
Match: FTSJ3 (FtsJ RNA 2'-O-methyltransferase 3 [Source:NCBI gene;Acc:100145257])

HSP 1 Score: 107.457 bits (267), Expect = 2.350e-25
Identity = 71/207 (34.30%), Postives = 118/207 (57.00%), Query Frame = 2

Query:  119 GADSNVWLSRQLSDPYVKRSRIESFRCRSAFKLIELDNKYKLLYPGITVLDCGAAPGSWSQVISRKCFVTNSASSLAIAIDKNFFQPIEHIICLSECDINSDSTISLMKEKLGTRKFNLVLSDMAPNASGIKDIDKHTMNQLNQMALKVAIENSCKGASFLFKMWSDMNSEKHLKDLILRFYKSVKIVKPPASRSDSSEIFLLCQGF 739
            G  + V  SR+  D +   ++   +R RSAFKLI+L+ K++ L     ++D  AAPG W QV ++   +    SSL I +D    +PI  ++ L E DI +++    +++ L T K ++VL+D APN       D  +   L+ MAL++A +   +G  F+ K++   + +  L  ++ +F+K V   KP ASRS+S+EIF++CQGF
Sbjct:   12 GKKAKVGKSRK--DKFYHLAKETGYRSRSAFKLIQLNRKFQFLPKARALVDLCAAPGGWLQVAAKFMPI----SSLIIGVDLVPIKPIPKVLTLQE-DITTEACRQTVRKHLQTWKADVVLNDGAPNVGANWTHDAFSQVHLSLMALRLACDCLSRGGWFITKIFRSSDYQSLLW-ILQQFFKKVNSTKPQASRSESAEIFVVCQGF 210

[Close]

BLAST of Ribosomal RNA large subunit methyltransferase E vs. Ensembl Xenopus
Match: FTSJ3 (FtsJ RNA 2'-O-methyltransferase 3 [Source:NCBI gene;Acc:100145257])

HSP 1 Score: 107.071 bits (266), Expect = 3.071e-25
Identity = 74/209 (35.41%), Postives = 119/209 (56.94%), Query Frame = 2

Query:  119 GADSNVWLSRQLSDPYVKRSRIESFRCRSAFKLIELDNKYKLLYPGITVLDCGAAPGSWSQVISRKCFVTNSASSLAIAIDKNFFQPIEHIICLSECDINSDSTISLMKEKLGTRKFNLVLSDMAPNASGIKDIDKHTMNQLNQMALKVAIENSCKGASFLFKMW--SDMNSEKHLKDLILRFYKSVKIVKPPASRSDSSEIFLLCQGF 739
            G  + V  SR+  D +   ++   +R RSAFKLI+L+ K++ L     ++D  AAPG W QV ++   +    SSL I +D    +PI  ++ L E DI +++    +++ L T K ++VL+D APN       D  +   L+ MAL++A +   +G  F+ K++  SD  S   L  ++ +F+K V   KP ASRS+S+EIF++CQGF
Sbjct:    2 GKKAKVGKSRK--DKFYHLAKETGYRSRSAFKLIQLNRKFQFLPKARALVDLCAAPGGWLQVAAKFMPI----SSLIIGVDLVPIKPIPKVLTLQE-DITTEACRQTVRKHLQTWKADVVLNDGAPNVGANWTHDAFSQVHLSLMALRLACDCLSRGGWFITKIFRSSDYQS---LLWILQQFFKKVNSTKPQASRSESAEIFVVCQGF 200

[Close]

BLAST of Ribosomal RNA large subunit methyltransferase E vs. Ensembl Xenopus
Match: FTSJ3 (FtsJ RNA 2'-O-methyltransferase 3 [Source:NCBI gene;Acc:100145257])

HSP 1 Score: 94.3597 bits (233), Expect = 5.662e-21
Identity = 67/207 (32.37%), Postives = 114/207 (55.07%), Query Frame = 2

Query:  119 GADSNVWLSRQLSDPYVKRSRIESFRCRSAFKLIELDNKYKLLYPGITVLDCGAAPGSWSQVISRKCFVTNSASSLAIAIDKNFFQPIEHIICLSECDINSDSTISLMKEKLGTRKFNLVLSDMAPNASGIKDIDKHTMNQLNQMALKVAIENSCKGASFLFKMWSDMNSEKHLKDLILRFYKSVKIVKPPASRSDSSEIFLLCQGF 739
            G  + V  SR+  D +   ++   +R RSAFKLI+L+ K++ L     ++D  AAPG+  + +S  C       S    +D    +PI  ++ L E DI +++    +++ L T K ++VL+D APN       D  +   L+ MAL++A +   +G  F+ K++   + +  L  ++ +F+K V   KP ASRS+S+EIF++CQGF
Sbjct:    2 GKKAKVGKSRK--DKFYHLAKETGYRSRSAFKLIQLNRKFQFLPKARALVDLCAAPGA-EKFVSLICLFFFPPPS---GVDLVPIKPIPKVLTLQE-DITTEACRQTVRKHLQTWKADVVLNDGAPNVGANWTHDAFSQVHLSLMALRLACDCLSRGGWFITKIFRSSDYQSLLW-ILQQFFKKVNSTKPQASRSESAEIFVVCQGF 200

[Close]

BLAST of Ribosomal RNA large subunit methyltransferase E vs. Ensembl Mouse
Match: Mrm2 (mitochondrial rRNA methyltransferase 2 [Source:MGI Symbol;Acc:MGI:1915267])

HSP 1 Score: 162.54 bits (410), Expect = 2.867e-48
Identity = 80/216 (37.04%), Postives = 133/216 (61.57%), Query Frame = 2

Query:  107 FFSKGADSNVWLSRQLSDPYVKRSRIESFRCRSAFKLIELDNKYKLLYPGITVLDCGAAPGSWSQVISRKCFVTNSASS----LAIAIDKNFFQPIEHIICLSECDINSDSTISLMKEKLGTRKFNLVLSDMAPNASGIKDIDKHTMNQLNQMALKVAIENSCKGASFLFKMWSDMNSEKH-LKDLILRFYKSVKIVKPPASRSDSSEIFLLCQGF 739
            +  +    ++WL+R L DP+VK +++ES+RCRSAFKL+E++ K+++L PG+ VLDCGAAPG+WSQV  ++   T + SS      + +D     P+     L   D+    T   + E L +R+ +++LSDMAPNA+GI+D+D   +  L    + +A++    G + L K W+   S+ H L+  + + ++S ++VKP ASR +SSE++LL   +
Sbjct:   24 YRGRTGAEHLWLTRHLKDPFVKAAKVESYRCRSAFKLLEMNEKHQILRPGLRVLDCGAAPGAWSQVAVQRVNATGADSSSPVGFVLGVDLLHIFPLAGATFLCPADVTDPRTFQKILELLPSRRADVILSDMAPNATGIRDLDHDKLISLCLTLVDMAVDILHPGGTLLCKTWA--GSKSHLLQKRLTQEFQSTRVVKPEASRKESSEVYLLATQY 237

[Close]

BLAST of Ribosomal RNA large subunit methyltransferase E vs. Ensembl Mouse
Match: Ftsj3 (FtsJ RNA methyltransferase homolog 3 (E. coli) [Source:MGI Symbol;Acc:MGI:1860295])

HSP 1 Score: 104.76 bits (260), Expect = 1.487e-24
Identity = 67/207 (32.37%), Postives = 115/207 (55.56%), Query Frame = 2

Query:  119 GADSNVWLSRQLSDPYVKRSRIESFRCRSAFKLIELDNKYKLLYPGITVLDCGAAPGSWSQVISRKCFVTNSASSLAIAIDKNFFQPIEHIICLSECDINSDSTISLMKEKLGTRKFNLVLSDMAPNASGIKDIDKHTMNQLNQMALKVAIENSCKGASFLFKMWSDMNSEKHLKDLILRFYKSVKIVKPPASRSDSSEIFLLCQGF 739
            G    V  SR+  D +   ++   +R RSAFKLI+L+ +++ L     +LD  AAPG W QV ++   V    SSL + +D    +P+ +++ L E DI ++     ++++L T K ++VL+D APN       D ++   L  MAL++A +   +G  F+ K++   + +  L  +  + +  V+  KP ASR +S+EIF++CQGF
Sbjct:    2 GKKGKVGKSRR--DKFYHLAKETGYRSRSAFKLIQLNRRFQFLQKARALLDLCAAPGGWLQVAAKFMPV----SSLIVGVDLVPIKPLPNVVTLQE-DITTERCRQALRKELKTWKVDVVLNDGAPNVGASWVHDAYSQAHLTLMALRLACDFLARGGCFITKVFRSRDYQPLLW-IFQQLFHRVQATKPQASRHESAEIFVVCQGF 200

[Close]

BLAST of Ribosomal RNA large subunit methyltransferase E vs. Ensembl Mouse
Match: Ftsj1 (FtsJ RNA methyltransferase homolog 1 (E. coli) [Source:MGI Symbol;Acc:MGI:1859648])

HSP 1 Score: 101.293 bits (251), Expect = 2.851e-24
Identity = 65/199 (32.66%), Postives = 105/199 (52.76%), Query Frame = 2

Query:  143 SRQLSDPYVKRSRIESFRCRSAFKLIELDNKYKLLYPGITVLDCGAAPGSWSQVISRKCFVTNSASSLAIAIDKNFFQPIEHIICLSECDINSDSTISLMKEKLGTRKFNLVLSDMAPNASGIKDIDKHTMNQLNQMALKVAIENSCKGASFLFKMWSDMNSEKHLKDLILRFYKSVKIVKPPASRSDSSEIFLLCQGF 739
            S+   D Y + ++   +R RSAFKL++LD +++L       +D  AAPGSWSQV+S+K  V    S   +A+D     P+  +I + + DI   ST   + +       +LV+ D AP+ +G+ D+D++   QL   AL +A      G  F+ K++   +       L + F+ SV   KP +SR+ S E F +CQG+
Sbjct:    5 SKDKRDVYYRLAKENGWRARSAFKLLQLDEEFQLFKGVKRAVDLCAAPGSWSQVLSQK--VGGQGSGQVVAVDLQAMAPLPGVIQI-QGDITQLSTAKEIIQHFEGCPADLVVCDGAPDVTGLHDVDEYMQAQLLLAALNIATHVLKLGGCFVAKIFRGRDVTLLYSQLRI-FFSSVLCAKPKSSRNSSIEAFAVCQGY 199

[Close]

BLAST of Ribosomal RNA large subunit methyltransferase E vs. Ensembl Mouse
Match: Ftsj1 (FtsJ RNA methyltransferase homolog 1 (E. coli) [Source:MGI Symbol;Acc:MGI:1859648])

HSP 1 Score: 100.908 bits (250), Expect = 2.880e-24
Identity = 65/199 (32.66%), Postives = 105/199 (52.76%), Query Frame = 2

Query:  143 SRQLSDPYVKRSRIESFRCRSAFKLIELDNKYKLLYPGITVLDCGAAPGSWSQVISRKCFVTNSASSLAIAIDKNFFQPIEHIICLSECDINSDSTISLMKEKLGTRKFNLVLSDMAPNASGIKDIDKHTMNQLNQMALKVAIENSCKGASFLFKMWSDMNSEKHLKDLILRFYKSVKIVKPPASRSDSSEIFLLCQGF 739
            S+   D Y + ++   +R RSAFKL++LD +++L       +D  AAPGSWSQV+S+K  V    S   +A+D     P+  +I + + DI   ST   + +       +LV+ D AP+ +G+ D+D++   QL   AL +A      G  F+ K++   +       L + F+ SV   KP +SR+ S E F +CQG+
Sbjct:    5 SKDKRDVYYRLAKENGWRARSAFKLLQLDEEFQLFKGVKRAVDLCAAPGSWSQVLSQK--VGGQGSGQVVAVDLQAMAPLPGVIQI-QGDITQLSTAKEIIQHFEGCPADLVVCDGAPDVTGLHDVDEYMQAQLLLAALNIATHVLKLGGCFVAKIFRGRDVTLLYSQLRI-FFSSVLCAKPKSSRNSSIEAFAVCQGY 199

[Close]

BLAST of Ribosomal RNA large subunit methyltransferase E vs. Ensembl Mouse
Match: Ftsj1 (FtsJ RNA methyltransferase homolog 1 (E. coli) [Source:MGI Symbol;Acc:MGI:1859648])

HSP 1 Score: 100.523 bits (249), Expect = 3.574e-24
Identity = 65/199 (32.66%), Postives = 105/199 (52.76%), Query Frame = 2

Query:  143 SRQLSDPYVKRSRIESFRCRSAFKLIELDNKYKLLYPGITVLDCGAAPGSWSQVISRKCFVTNSASSLAIAIDKNFFQPIEHIICLSECDINSDSTISLMKEKLGTRKFNLVLSDMAPNASGIKDIDKHTMNQLNQMALKVAIENSCKGASFLFKMWSDMNSEKHLKDLILRFYKSVKIVKPPASRSDSSEIFLLCQGF 739
            S+   D Y + ++   +R RSAFKL++LD +++L       +D  AAPGSWSQV+S+K  V    S   +A+D     P+  +I + + DI   ST   + +       +LV+ D AP+ +G+ D+D++   QL   AL +A      G  F+ K++   +       L + F+ SV   KP +SR+ S E F +CQG+
Sbjct:    5 SKDKRDVYYRLAKENGWRARSAFKLLQLDEEFQLFKGVKRAVDLCAAPGSWSQVLSQK--VGGQGSGQVVAVDLQAMAPLPGVIQI-QGDITQLSTAKEIIQHFEGCPADLVVCDGAPDVTGLHDVDEYMQAQLLLAALNIATHVLKLGGCFVAKIFRGRDVTLLYSQLRI-FFSSVLCAKPKSSRNSSIEAFAVCQGY 199

[Close]

BLAST of Ribosomal RNA large subunit methyltransferase E vs. UniProt/SwissProt
Match: sp|Q9VDT6|MRM2_DROME (rRNA methyltransferase 2, mitochondrial OS=Drosophila melanogaster OX=7227 GN=CG11447 PE=2 SV=1)

HSP 1 Score: 172.17 bits (435), Expect = 3.373e-51
Identity = 91/235 (38.72%), Postives = 135/235 (57.45%), Query Frame = 2

Query:   50 FCYIMFDYLKCKYVSKLARFF-SKGADSNVWLSRQLSDPYVKRSRIESFRCRSAFKLIELDNKYKLLYPGITVLDCGAAPGSWSQVISRKCFVTN----SASSLAIAIDKNFFQPIEHIICLSECDINSDSTISLMKEKLGTRKFNLVLSDMAPNASGIKDIDKHTMNQLNQMALKVAIENSCKGASFLFKMWSDMNSEKHLKDLILRFYKSVKIVKPPASRSDSSEIFLLCQGF 739
            F  ++   +  KY  +  R    +   S  WL+RQL+DPYV+++R+ ++RCRSAFKL+E+D+KY +L PG TVL+CGAAPGSW+QV   +         +      +ID   F  +         D  S      ++E L  RK N VLSDMAPNA+G++ +D+ ++  L    L+ A+  S   A  + K+W + +  K  +D+ LRFY+ VK VKP ASR DS+E FL+ + F
Sbjct:   11 FKRLLHTEIGGKYAKQQPRNLKGRSKSSQEWLTRQLADPYVEKARMMNYRCRSAFKLLEIDDKYGILRPGDTVLECGAAPGSWTQVAVERTNANGKQERAPQGAVFSIDLLHFHAVPGATIFGGMDFTSSLAQKRLREALQDRKVNCVLSDMAPNATGVRMLDQESITNLCYEVLRFALAMSAPQAHLVVKVWDNGDVPKLERDM-LRFYEKVKRVKPRASRGDSAEHFLVARNF 244

[Close]

BLAST of Ribosomal RNA large subunit methyltransferase E vs. UniProt/SwissProt
Match: sp|Q9CPY0|MRM2_MOUSE (rRNA methyltransferase 2, mitochondrial OS=Mus musculus OX=10090 GN=Mrm2 PE=1 SV=1)

HSP 1 Score: 162.54 bits (410), Expect = 2.005e-47
Identity = 80/216 (37.04%), Postives = 133/216 (61.57%), Query Frame = 2

Query:  107 FFSKGADSNVWLSRQLSDPYVKRSRIESFRCRSAFKLIELDNKYKLLYPGITVLDCGAAPGSWSQVISRKCFVTNSASS----LAIAIDKNFFQPIEHIICLSECDINSDSTISLMKEKLGTRKFNLVLSDMAPNASGIKDIDKHTMNQLNQMALKVAIENSCKGASFLFKMWSDMNSEKH-LKDLILRFYKSVKIVKPPASRSDSSEIFLLCQGF 739
            +  +    ++WL+R L DP+VK +++ES+RCRSAFKL+E++ K+++L PG+ VLDCGAAPG+WSQV  ++   T + SS      + +D     P+     L   D+    T   + E L +R+ +++LSDMAPNA+GI+D+D   +  L    + +A++    G + L K W+   S+ H L+  + + ++S ++VKP ASR +SSE++LL   +
Sbjct:   24 YRGRTGAEHLWLTRHLKDPFVKAAKVESYRCRSAFKLLEMNEKHQILRPGLRVLDCGAAPGAWSQVAVQRVNATGADSSSPVGFVLGVDLLHIFPLAGATFLCPADVTDPRTFQKILELLPSRRADVILSDMAPNATGIRDLDHDKLISLCLTLVDMAVDILHPGGTLLCKTWA--GSKSHLLQKRLTQEFQSTRVVKPEASRKESSEVYLLATQY 237

[Close]

BLAST of Ribosomal RNA large subunit methyltransferase E vs. UniProt/SwissProt
Match: sp|Q9UI43|MRM2_HUMAN (rRNA methyltransferase 2, mitochondrial OS=Homo sapiens OX=9606 GN=MRM2 PE=1 SV=1)

HSP 1 Score: 157.918 bits (398), Expect = 1.146e-45
Identity = 80/207 (38.65%), Postives = 127/207 (61.35%), Query Frame = 2

Query:  119 GADSNVWLSRQLSDPYVKRSRIESFRCRSAFKLIELDNKYKLLYPGITVLDCGAAPGSWSQVISRKCFVTNSASS----LAIAIDKNFFQPIEHIICLSECDINSDSTISLMKEKLGTRKFNLVLSDMAPNASGIKDIDKHTMNQLNQMALKVAIENSCKGASFLFKMWSDMNSEKHLKDLILRFYKSVKIVKPPASRSDSSEIFLL 727
            GA+ ++WL+R L DP+VK +++ES+RCRSAFKL+E++ ++++L PG+ VLDCGAAPG+WSQV  +K     +  S      + +D     P+E    L   D+    T   + E L  R+ +++LSDMAPNA+G +D+D   +  L    L V  +    G +FL K W+   S + L+  +   +++V+I+KP ASR +SSE++ L
Sbjct:   29 GAE-HLWLTRHLRDPFVKAAKVESYRCRSAFKLLEVNERHQILRPGLRVLDCGAAPGAWSQVAVQKVNAAGTDPSSPVGFVLGVDLLHIFPLEGATFLCPADVTDPRTSQRILEVLPGRRADVILSDMAPNATGFRDLDHDRLISLCLTLLSVTPDILQPGGTFLCKTWAGSQSRR-LQRRLTEEFQNVRIIKPEASRKESSEVYFL 233

[Close]

BLAST of Ribosomal RNA large subunit methyltransferase E vs. UniProt/SwissProt
Match: sp|A5EHP2|RLME_BRASB (Ribosomal RNA large subunit methyltransferase E OS=Bradyrhizobium sp. (strain BTAi1 / ATCC BAA-1182) OX=288000 GN=rlmE PE=3 SV=1)

HSP 1 Score: 142.895 bits (359), Expect = 4.070e-40
Identity = 77/204 (37.75%), Postives = 119/204 (58.33%), Query Frame = 2

Query:  128 SNVWLSRQLSDPYVKRSRIESFRCRSAFKLIELDNKYKLLYPGITVLDCGAAPGSWSQVISRKCFVTNSASSLAIAIDKNFFQPIEHIICLSECDINSDSTISLMKEKLGTRKFNLVLSDMAPNASGIKDIDKHTMNQLNQMALKVAIENSCKGASFLFKMWSDMNSEKHLKDLILRFYKSVKIVKPPASRSDSSEIFLLCQGF 739
            S +WL RQL+DPYV +++ + +R R+ +KLIE+D+KY LL PG+TV+D GAAPG WSQ+ +R+     +     IAID      +   +  ++ D ++      ++  LG R  ++V+SDMA N +G +  D+  +  L ++A   A E    G SFL K +    ++  L   + R Y +V+ VKP ASR DSSE ++L  GF
Sbjct:   23 SKLWLERQLNDPYVAQAKRDGYRSRATYKLIEIDDKYHLLKPGMTVVDLGAAPGGWSQIAARRVGA-EAGKGKVIAIDLLEMGEVPG-VTFTQMDFHAQDAPEKLRAMLGGRA-DVVMSDMAANTTGHRKTDQLRIVGLVELAAHFAGEVLKPGGSFLAKTFQS-GADAELLAQLKRDYATVRHVKPAASRQDSSERYVLAMGF 222

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BLAST of Ribosomal RNA large subunit methyltransferase E vs. UniProt/SwissProt
Match: sp|Q8P9Y1|RLME_XANCP (Ribosomal RNA large subunit methyltransferase E OS=Xanthomonas campestris pv. campestris (strain ATCC 33913 / DSM 3586 / NCPPB 528 / LMG 568 / P 25) OX=190485 GN=rlmE PE=3 SV=2)

HSP 1 Score: 142.124 bits (357), Expect = 5.113e-40
Identity = 76/208 (36.54%), Postives = 121/208 (58.17%), Query Frame = 2

Query:  113 SKGADSNVWLSRQLSDPYVKRSRIESFRCRSAFKLIELDNKYKLLYPGITVLDCGAAPGSWSQVISRKCFVTNSASSLAIAIDKNFFQPIEHIICLSECDINSDSTISLMKEKLGTRKFNLVLSDMAPNASGIKDIDKHTMNQLNQMALKVAIENSCKGASFLFKMWSDMNSEKHLKDLILRFYKSVKIVKPPASRSDSSEIFLLCQG 736
            S+   S  WL    +DP+VK+++ E  R R+A+KL EL  + +LL PG+ V+D GAAPG WSQ + +    +  AS   +A+D     P+  +  L   D    + +S  +  LG    +LVLSDMAPN SG+  +D+  M  L ++A++ A  +   G +FL K++  + S+ ++++L  R Y+ V I KP ASR  S+E+++L QG
Sbjct:    3 SRSKSSQRWLKEHFADPFVKKAQAEGMRSRAAYKLEELLQRDRLLKPGMVVVDLGAAPGGWSQQVRK----SMGASGRVVALDILEMPPLAGVEFL-HGDFREQAVLSEFEAMLGDVPVDLVLSDMAPNKSGMDAVDQPRMMHLAELAMEFADTHLKVGGAFLIKLFQGVGSDDYIREL-RRRYEKVTIRKPAASRKRSAEVYVLGQG 204

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BLAST of Ribosomal RNA large subunit methyltransferase E vs. TrEMBL
Match: A0A2J7QN05 (rRNA methyltransferase 2, mitochondrial OS=Cryptotermes secundus OX=105785 GN=B7P43_G06952 PE=3 SV=1)

HSP 1 Score: 194.512 bits (493), Expect = 2.379e-57
Identity = 96/208 (46.15%), Postives = 136/208 (65.38%), Query Frame = 2

Query:  128 SNVWLSRQLSDPYVKRSRIESFRCRSAFKLIELDNKYKLLYPGITVLDCGAAPGSWSQVISRKCFVTN----SASSLAIAIDKNFFQPIEHIICLSECDINSDSTISLMKEKLGTRKFNLVLSDMAPNASGIKDIDKHTMNQLNQMALKVAIENSCKGASFLFKMWSDMNSEKHLKDLILRFYKSVKIVKPPASRSDSSEIFLLCQGF 739
            S  WL+RQL+DPYV+++R  ++RCRSAFKLIE+D+++K+L PG  V+DCGAAPGSW+QV + +   T       +   IA+D+N   PIE  I +   D  + S  + + E L  +K N+VLSDMAPNA+G++DID   +  L   AL+ A++ S  G S L K+W    S +  +D I +FY  V++VKPPASR DS+E FLL + F
Sbjct:   45 SQEWLTRQLTDPYVEKARRLNYRCRSAFKLIEIDDRFKVLSPGDYVVDCGAAPGSWTQVAAHRVNATGKDAKKPAGQVIAVDRNPIYPIEGAILMGGVDFTAASAQAKVLELLNGKKVNIVLSDMAPNATGVRDIDHENIVHLAYSALRFALQVSYVGGSVLLKIWDGRESNRLEQD-IAKFYNHVRVVKPPASRGDSAEKFLLARMF 251

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BLAST of Ribosomal RNA large subunit methyltransferase E vs. TrEMBL
Match: A0A444TDL6 (rRNA methyltransferase 2, mitochondrial OS=Armadillidium vulgare OX=13347 GN=Avbf_03964 PE=3 SV=1)

HSP 1 Score: 193.741 bits (491), Expect = 4.826e-57
Identity = 104/229 (45.41%), Postives = 151/229 (65.94%), Query Frame = 2

Query:   56 YIMFDYLKCKYVSKLARFFSKGADSNVWLSRQLSDPYVKRSRIESFRCRSAFKLIELDNKYKLLYPGITVLDCGAAPGSWSQVISRKCFVTN-SASSLAIAIDKNFFQPIEHIICLSECDINSDSTISLMKEKLGTRKFNLVLSDMAPNASGIKDIDKHTMNQLNQMALKVAIENSCKGASFLFKMWSDMNSEKHLKDLILRFYKSVKIVKPPASRSDSSEIFLLCQGF 739
            YI    +  K + K  + FSK   S  WL+R L+DPYVKR++ E +R RSAFKLIE+D K+KLL PG  V+DCGAAPGSW+QV+  K    N + +   I++D ++F+ +E  ICL   D N+DST   ++++L  +K +L+LSDMAP ASG +D+D   +  L+   L+ AI+N+  G+ FL K+W D    K  K+ + ++Y+ VK+VKP ASR+DSSE F+L + F
Sbjct:   21 YISTSQISYKVIPKNLKKFSKS--SQDWLTRHLNDPYVKRAKYEHYRARSAFKLIEIDEKHKLLGPGKIVIDCGAAPGSWTQVVVSKLKDKNGNQNGKVISVDLSYFEKVEGSICLPGHDFNADSTQLAIEKELDGKKVHLILSDMAPKASGARDLDHTQIIDLSYSVLRFAIKNARYGSDFLCKVW-DGYKLKEFKNELEKYYERVKLVKPNASRTDSSETFVLGRNF 246

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BLAST of Ribosomal RNA large subunit methyltransferase E vs. TrEMBL
Match: A0A232FKL9 (FtsJ domain-containing protein OS=Trichomalopsis sarcophagae OX=543379 GN=TSAR_014237 PE=3 SV=1)

HSP 1 Score: 191.815 bits (486), Expect = 2.557e-56
Identity = 97/216 (44.91%), Postives = 137/216 (63.43%), Query Frame = 2

Query:  113 SKGADSNVWLSRQLSDPYVKRSRIESFRCRSAFKLIELDNKYKLLYPGITVLDCGAAPGSWSQVISRKCFVTNSASSL-------AIAIDKNFFQPIEHIICLSECDINSDSTISLMKEKLGTRKFNLVLSDMAPNASGIKDIDKHTMNQLNQMALKVAIENSCKGASFLFKMWSDMNSEKHLKDLILRFYKSVKIVKPPASRSDSSEIFLLCQGF 739
             K   S  WLSRQ  DPYV+++R E++RCRSAFKL+E++ K+++L PG+ V+DCGAAPGSW+QV ++   +TNS   +        IAIDK    PIE        D  +    +++K  LG +   +V+SDMAPNASGIKD+D   + +L  MA K AIE SC   +F+ K+W      K  +DL  RFY++VKI +P A+R +SSE F++ +GF
Sbjct:   28 GKKHSSQQWLSRQFKDPYVEKARQENYRCRSAFKLLEINRKHRILSPGLHVVDCGAAPGSWTQVATQ---LTNSHGKMLGEPVGKVIAIDKLPIHPIEGATVYGNLDFTTKEAQNILKTALGGKFVEVVMSDMAPNASGIKDLDHENIIKLAYMAFKFAIEVSCYEGTFIVKVWDGYKCTKLEEDLA-RFYRNVKIARPQATRDESSEKFIVARGF 239

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BLAST of Ribosomal RNA large subunit methyltransferase E vs. TrEMBL
Match: K7IZI4 (FtsJ domain-containing protein OS=Nasonia vitripennis OX=7425 PE=3 SV=1)

HSP 1 Score: 189.119 bits (479), Expect = 1.328e-55
Identity = 94/216 (43.52%), Postives = 138/216 (63.89%), Query Frame = 2

Query:  113 SKGADSNVWLSRQLSDPYVKRSRIESFRCRSAFKLIELDNKYKLLYPGITVLDCGAAPGSWSQVISRKCFVTNSASSL-------AIAIDKNFFQPIEHIICLSECDINSDSTISLMKEKLGTRKFNLVLSDMAPNASGIKDIDKHTMNQLNQMALKVAIENSCKGASFLFKMWSDMNSEKHLKDLILRFYKSVKIVKPPASRSDSSEIFLLCQGF 739
             K   S  WLSRQ  DPYV+++R E++RCRSAFKL+E++ K+++L PG+ V+DCGAAPGSW+QV ++   +TNS   +        IAIDK    PIE        D  ++   +++K  LG +   +V+SDMAPNASG++D+D   + +L  MA K AIE SC   +F+ K+W      K  +DL  RF+++VKI +P A+R +SSE F++ +GF
Sbjct:   10 GKKHSSQQWLSRQFKDPYVEKARQENYRCRSAFKLLEINRKHRILSPGLHVVDCGAAPGSWTQVATQ---LTNSHGKMLGEQVGKVIAIDKLPIHPIEGATVYGNLDFTTEDAQNILKAALGGKFVEVVMSDMAPNASGVRDLDHENIIKLAYMAFKFAIEVSCYEGTFIVKVWDGHKCPKLEEDLA-RFFRNVKIARPQATRDESSEKFIIARGF 221

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BLAST of Ribosomal RNA large subunit methyltransferase E vs. TrEMBL
Match: A0A182XJ46 (FtsJ domain-containing protein OS=Anopheles quadriannulatus OX=34691 PE=3 SV=1)

HSP 1 Score: 187.963 bits (476), Expect = 6.422e-55
Identity = 95/213 (44.60%), Postives = 133/213 (62.44%), Query Frame = 2

Query:  113 SKGADSNVWLSRQLSDPYVKRSRIESFRCRSAFKLIELDNKYKLLYPGITVLDCGAAPGSWSQVISRKC----FVTNSASSLAIAIDKNFFQPIEHIICLSECDINSDSTISLMKEKLGTRKFNLVLSDMAPNASGIKDIDKHTMNQLNQMALKVAIENSCKGASFLFKMWSDMNSEKHLKDLILRFYKSVKIVKPPASRSDSSEIFLLCQGF 739
             K   S  WL+RQL DPYV+R+++ ++RCRSAFKL+E+DNKY L+ PG TV+DCGA+PGSW+Q+  ++      + N    + + +D     PIEH I     D     T   ++  LG R+ + VLSDMAPNASGI+ +D+  +  L    L+ AI  S   AS L K+W + +  K L+  IL +YK+VK VKP ASR DS+E F+L +GF
Sbjct:   26 GKSKSSQEWLTRQLRDPYVERAKMMNYRCRSAFKLLEIDNKYGLVKPGYTVIDCGASPGSWTQIAVKQSNADGGLPNKPKGMVVGVDLLQIYPIEHAILFGNSDFLRKETQDKIRASLGERRVDCVLSDMAPNASGIRALDQENITTLCYAVLRFAILMSTPNASLLMKVWDNGDVPK-LEKSILEYYKTVKRVKPRASRDDSAENFILARGF 237

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BLAST of Ribosomal RNA large subunit methyltransferase E vs. Ensembl Cavefish
Match: mrm2 (mitochondrial rRNA methyltransferase 2 [Source:NCBI gene;Acc:103022050])

HSP 1 Score: 157.918 bits (398), Expect = 1.187e-46
Identity = 87/214 (40.65%), Postives = 130/214 (60.75%), Query Frame = 2

Query:  119 GADSNVWLSRQLSDPYVKRSRIESFRCRSAFKLIELDNKYKLLYPGITVLDCGAAPGSWSQVISRKCFVTNSASSL-------AIAIDKNFFQPIEHIICLSECDINSDSTISLMKEKLGTRKFNLVLSDMAPNASGIKDIDKHTMNQLNQMALKVAIENSCKGASFLFKMWSDMNSEKHLKDLILRFYKSVKIVKPPASRSDSSEIFLLCQGF 739
            GA+   WL RQLSDP+VK ++ +++RCRSAFKL E+D++Y+LL PG++V+DCGAAPG+WSQV  ++    NSA           I ID  +  P+E    L   DI   +T + ++  L     +++LSDMAPNASG++++D   +  +    L++A      G S + K W    + K L+D + R ++ VK VKP ASR DSSE++ L + F
Sbjct:   31 GAEQR-WLVRQLSDPFVKAAQTQNYRCRSAFKLREIDDQYRLLSPGLSVIDCGAAPGAWSQVAVQR---VNSAGERPDVPRGSVIGIDLLYIAPLEGAHFLCNQDITHPATHAELQRLLPQAYADVILSDMAPNASGLRELDHERLVSMCLSLLELADRVLRPGGSLVCKYWDGALAHK-LRDGLARVFRDVKTVKPKASRKDSSELYFLARTF 239

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BLAST of Ribosomal RNA large subunit methyltransferase E vs. Ensembl Cavefish
Match: ftsj3 (FtsJ RNA 2'-O-methyltransferase 3 [Source:NCBI gene;Acc:103026698])

HSP 1 Score: 112.849 bits (281), Expect = 1.878e-27
Identity = 71/200 (35.50%), Postives = 113/200 (56.50%), Query Frame = 2

Query:  140 LSRQLSDPYVKRSRIESFRCRSAFKLIELDNKYKLLYPGITVLDCGAAPGSWSQVISRKCFVTNSASSLAIAIDKNFFQPIEHIICLSECDINSDSTISLMKEKLGTRKFNLVLSDMAPNASGIKDIDKHTMNQLNQMALKVAIENSCKGASFLFKMWSDMNSEKHLKDLILRFYKSVKIVKPPASRSDSSEIFLLCQGF 739
            + +   D +   ++   +R RS+FKLI+L+ K+  L     ++D  AAPG W QV S+   V    SSL I +D    +PI  ++ L E DI ++     ++++L T K ++VL+D APN       D  +   L  MALK+A E   KG SF+ K++   + +  L  +  +F+K V+  KP ASR++S+EIF++CQGF
Sbjct:    7 VGKTRKDKFYHLAKETGYRSRSSFKLIQLNRKFNFLQKARALVDLCAAPGGWLQVASKFMPV----SSLIIGVDLVPIKPIPGVVALQE-DITTEKCRQALRKELQTWKVDVVLNDGAPNVGANWQHDAFSQAHLTLMALKLACEFLAKGGSFVTKVFRSKDYQ-PLMWIFQQFFKKVQATKPQASRNESAEIFVVCQGF 200

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BLAST of Ribosomal RNA large subunit methyltransferase E vs. Ensembl Cavefish
Match: ftsj1 (FtsJ RNA 2'-O-methyltransferase 1 [Source:NCBI gene;Acc:103035718])

HSP 1 Score: 98.2117 bits (243), Expect = 2.248e-23
Identity = 64/200 (32.00%), Postives = 104/200 (52.00%), Query Frame = 2

Query:  143 SRQLSDPYVKRSRIESFRCRSAFKLIELDNKYKLLYPGITVLDCGAAPGSWSQVISRKCFVTNSASSLAI-AIDKNFFQPIEHIICLSECDINSDSTISLMKEKLGTRKFNLVLSDMAPNASGIKDIDKHTMNQLNQMALKVAIENSCKGASFLFKMWSDMNSEKHLKDLILRFYKSVKIVKPPASRSDSSEIFLLCQGF 739
            S+   D Y + ++ E +R RSAFKL++LD ++ L       +D  AAPGSWSQV+SRK     S   + I A+D     P+  +  + + DI   ST   +      +  +LV+ D AP+ +G+ D+D++   QL   AL +       G +F+ K++   +       L + F+ SV   KP +SR+ S E F++CQ +
Sbjct:    5 SKDKRDIYYRLAKEEGWRARSAFKLLQLDEEFNLFKGVSRAVDLCAAPGSWSQVLSRKLRGKESNEDVKIVAVDLQAMAPLPGVTQI-QGDITKISTAQEIIRHFEGQSADLVVCDGAPDVTGLHDVDEYIQAQLLLAALNITTHVLKPGGNFVAKIFRGKDVTLLYSQLKI-FFSSVTCAKPRSSRNSSIEAFVVCQNY 202

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Query:  143 SRQLSDPYVKRSRIESFRCRSAFKLIELDNKYKLLYPGITVLDCGAAPGSWSQVISRKCFVTNSASSLAI-AIDKNFFQPIEHIICLSECDINSDSTISLMKEKLGTRKFNLVLSDMAPNASGIKDIDKHTMNQLNQMALKVAIENSCKGASFLFKMWSDMNSEKHLKDLILRFYKSVKIVKPPASRSDSSEIFLLCQGF 739
            S+   D Y + ++ E +R RSAFKL++LD ++ L       +D  AAPGSWSQV+SRK     S   + I A+D     P+  +  + + DI   ST   +      +  +LV+ D AP+ +G+ D+D++   QL   AL +       G +F+ K++   +       L + F+ SV   KP +SR+ S E F++CQ +
Sbjct:    5 SKDKRDIYYRLAKEEGWRARSAFKLLQLDEEFNLFKGVSRAVDLCAAPGSWSQVLSRKLRGKESNEDVKIVAVDLQAMAPLPGVTQI-QGDITKISTAQEIIRHFEGQSADLVVCDGAPDVTGLHDVDEYIQAQLLLAALNITTHVLKPGGNFVAKIFRGKDVTLLYSQLKI-FFSSVTCAKPRSSRNSSIEAFVVCQNY 202

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BLAST of Ribosomal RNA large subunit methyltransferase E vs. Ensembl Cavefish
Match: ftsj1 (FtsJ RNA 2'-O-methyltransferase 1 [Source:NCBI gene;Acc:103035718])

HSP 1 Score: 85.8853 bits (211), Expect = 6.506e-19
Identity = 60/200 (30.00%), Postives = 97/200 (48.50%), Query Frame = 2

Query:  143 SRQLSDPYVKRSRIESFRCRSAFKLIELDNKYKLLYPGITVLDCGAAPGSWSQVISRKCFVTNSASSLAI-AIDKNFFQPIEHIICLSECDINSDSTISLMKEKLGTRKFNLVLSDMAPNASGIKDIDKHTMNQLNQMALKVAIENSCKGASFLFKMWSDMNSEKHLKDLILRFYKSVKIVKPPASRSDSSEIFLLCQGF 739
            S+   D Y + ++ E +R RSAFKL++LD ++ L       +D  AAPGSWSQV+SRK     S   + I A+D     P+  +  + + DI   ST   +      +  +LV+ D AP+ +G+ D+D++   QL     +       K  + L+               +  F+ SV   KP +SR+ S E F++CQ +
Sbjct:    5 SKDKRDIYYRLAKEEGWRARSAFKLLQLDEEFNLFKGVSRAVDLCAAPGSWSQVLSRKLRGKESNEDVKIVAVDLQAMAPLPGVTQI-QGDITKISTAQEIIRHFEGQSADLVVCDGAPDVTGLHDVDEYIQAQLLLAIFR------GKDVTLLYSQ-------------LKIFFSSVTCAKPRSSRNSSIEAFVVCQNY 184

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BLAST of Ribosomal RNA large subunit methyltransferase E vs. Ensembl Sea Lamprey
Match: ftsj1 (FtsJ RNA 2'-O-methyltransferase 1 [Source:ZFIN;Acc:ZDB-GENE-041114-83])

HSP 1 Score: 93.9745 bits (232), Expect = 1.061e-22
Identity = 63/201 (31.34%), Postives = 103/201 (51.24%), Query Frame = 2

Query:  143 SRQLSDPYVKRSRIESFRCRSAFKLIELDNKYKLLYPGITVLDCGAAPGSWSQVISRKCFVTNSASSLA--IAIDKNFFQPIEHIICLSECDINSDSTISLMKEKLGTRKFNLVLSDMAPNASGIKDIDKHTMNQLNQMALKVAIENSCKGASFLFKMWSDMNSEKHLKDLILRFYKSVKIVKPPASRSDSSEIFLLCQGF 739
            S+   D Y + ++ E +R RSAFKL++LD ++ L       +D  AAPGSWSQV+SRK    +   S A  +A+D     P+  +I L + DI   ST   + +    +  +LV+ D AP+ +G+ DID++   QL   AL +      +G +F+ K++   +       L + F+  V   KP  +     E F++CQ +
Sbjct:    5 SKDKRDIYYRLAKEEGWRARSAFKLLQLDEEFNLFQGVSHAVDLCAAPGSWSQVLSRKLRGEDGKKSDAKIVAVDLQAMAPLPGVIQL-QGDITKVSTAQEIIKHFEGQPSDLVVCDGAPDVTGLHDIDEYIQAQLLLAALNITSHVLKRGGTFVAKIFRGKDVTLLFSQLKV-FFPLVTCAKPNTTLPVVPEAFVVCQNY 203

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BLAST of Ribosomal RNA large subunit methyltransferase E vs. Ensembl Yeast
Match: TRM7 (2'-O-ribose methyltransferase; methylates the 2'-O-ribose of tRNA-Phe, tRNA-Trp, and tRNA-Leu at positions C32 and N34 of tRNA anticodon loop; crucial biological role likely modification of tRNA-Phe; interacts with Trm732p and Rtt10p in 2'-O-methylation of C32 and N34 substrate tRNAs, respectively; yeast null mutant can be functionally complemented by human FTSJ1, mutations in which have been implicated in nonsyndromic X-linked intellectual disability (NSXLID) [Source:SGD;Acc:S000000265])

HSP 1 Score: 105.531 bits (262), Expect = 6.417e-27
Identity = 74/230 (32.17%), Postives = 123/230 (53.48%), Query Frame = 2

Query:  143 SRQLSDPYVKRSRIESFRCRSAFKLIELDNKYKLLY-PGIT-VLDCGAAPGSWSQVISRKCFVTNSASSLA----IAIDKNFFQPIEHIICLSECDINSDSTISLMKEKLGTRKFNLVLSDMAPNASGIKDIDKHTMNQLNQMALKVAIENSCKGASFLFKMWSDMNSEKHLKDLILRFYKSVKIVKPPASRSDSSEIFLLCQGFGE*NINN*RAIFNTSGRQLFY*FFL 814
            S+   D Y ++++ + +R RSAFKL++L++++  L  P +  V+D  AAPGSWSQV+SRK F  + +S       +++D     PI H+  L + DI    T++ + +  G  K + V SD AP+ +G+ D+D++   QL   AL++      KG +F+ K++   + +     L   F K V   KP +SR  S E F++C G+   +    +   NTS  + F   FL
Sbjct:    5 SKDKRDLYYRKAKEQGYRARSAFKLLQLNDQFHFLDDPNLKRVVDLCAAPGSWSQVLSRKLFDESPSSDKEDRKIVSVDLQPMSPIPHVTTL-QADITHPKTLARILKLFGNEKADFVCSDGAPDVTGLHDLDEYVQQQLIMSALQLTACILKKGGTFVAKIFRGRDIDMLYSQLGYLFDKIV-CAKPRSSRGTSLEAFIVCLGYNPPSNWTPKLDVNTSVDEFFQGCFL 232

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BLAST of Ribosomal RNA large subunit methyltransferase E vs. Ensembl Yeast
Match: SPB1 (AdoMet-dependent methyltransferase; involved in rRNA processing and 60S ribosomal subunit maturation; methylates G2922 in the tRNA docking site of the large subunit rRNA and in the absence of snR52, U2921; suppressor of PAB1 mutants [Source:SGD;Acc:S000000559])

HSP 1 Score: 101.679 bits (252), Expect = 1.527e-24
Identity = 69/195 (35.38%), Postives = 111/195 (56.92%), Query Frame = 2

Query:  158 DPYVKRSRIESFRCRSAFKLIELDNKY-KLLYPGITVLDCGAAPGSWSQVISRKCFVTNSASSLAIAIDKNFFQPIEHIICLSECDINSDSTISLMKEKLGTRKFNLVLSDMAPNASGIKDIDKHTMNQLNQMALKVAIENSCKGASFLFKMWSDMNSEKHLKDLILRFYKSVKIVKPPASRSDSSEIFLLCQGF 739
            D Y   ++ + +R RS+FK+I+++ KY   L     V+D  AAPGSW QV S+ C V    +SL I +D    +P+ ++I   + DI ++   S ++  + T K + VL D APN       D  T +QL   ALK+A+EN     +F+ K++   +  K L  +  + ++ V+  KPPASR+ S+EIF++C+GF
Sbjct:   14 DRYYYLAKEKGYRARSSFKIIQINEKYGHFLEKSKVVIDLCAAPGSWCQVASKLCPV----NSLIIGVDIVPMKPMPNVITF-QSDITTEDCRSKLRGYMKTWKADTVLHDGAPNVGLGWVQDAFTQSQLTLQALKLAVENLVVNGTFVTKIFRSKDYNK-LIWVFQQLFEKVEATKPPASRNVSAEIFVVCKGF 202

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BLAST of Ribosomal RNA large subunit methyltransferase E vs. Ensembl Yeast
Match: MRM2 (Mitochondrial 2' O-ribose methyltransferase; required for methylation of U(2791) in 21S rRNA; MRM2 deletion confers thermosensitive respiration and loss of mitochondrial DNA; has similarity to Spb1p and Trm7p, and to E. coli FtsJ/RrmJ [Source:SGD;Acc:S000003104])

HSP 1 Score: 76.2554 bits (186), Expect = 2.046e-16
Identity = 34/80 (42.50%), Postives = 54/80 (67.50%), Query Frame = 2

Query:  131 NVWLSRQLSDPYVKRSRIESFRCRSAFKLIELDNKYKLLYPGIT---VLDCGAAPGSWSQVISRKCFVTNSASSLAIAID 361
            N WL+RQL DPY K +++++ R R+AFKL+++D+KY+L     T   +LD G APG+WSQV  ++     S +S+ + +D
Sbjct:   29 NRWLNRQLKDPYTKEAKVQNLRSRAAFKLMQIDDKYRLFSKNRTDQRILDLGYAPGAWSQVARQRS----SPNSMILGVD 104

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BLAST of Ribosomal RNA large subunit methyltransferase E vs. Ensembl Nematostella
Match: EDO44102 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RWX8])

HSP 1 Score: 148.288 bits (373), Expect = 7.572e-44
Identity = 79/205 (38.54%), Postives = 116/205 (56.59%), Query Frame = 2

Query:  128 SNVWLSRQLSDPYVKRSRIESFRCRSAFKLIELDNKYKLLYPGITVLDCGAAPGSWSQV-ISRKCFVTNSASSLAIAIDKNFFQPIEHIICLSECDINSDSTISLMKEKLGTRKFNLVLSDMAPNASGIKDIDKHTMNQLNQMALKVAIENSCKGASFLFKMWSDMNSEKHLKDLILRFYKSVKIVKPPASRSDSSEIFLLCQGF 739
            S  WL R L+DPYVK++  +++RCRSA+KLI+LD+KY  L PG  V+DCGA+PGSW+QV + R          L +AID    + I   + +  CD    +T + +   L +   N++LSDMAPN+SG   +D   +  L   A +   +    G  FL K+W    +   ++ ++ R +K VK  KP ASR DS EI++   GF
Sbjct:    5 STRWLRRHLADPYVKKASEDNYRCRSAYKLIQLDDKYHFLLPGHVVIDCGASPGSWTQVAVERVIPNIGGEQGLVVAIDLLDIKAIPGAVIMGRCDFTHKATQTKILSLLPSFGVNVILSDMAPNSSGNHSLDHEAILDLCDSAFEFGQKTLRPGGVFLCKLWDGRGTVDFMQ-MLKRSFKLVKKCKPQASRKDSPEIYIYAAGF 208

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BLAST of Ribosomal RNA large subunit methyltransferase E vs. Ensembl Nematostella
Match: EDO47532 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RM32])

HSP 1 Score: 111.309 bits (277), Expect = 1.129e-28
Identity = 70/200 (35.00%), Postives = 116/200 (58.00%), Query Frame = 2

Query:  140 LSRQLSDPYVKRSRIESFRCRSAFKLIELDNKYKLLYPGITVLDCGAAPGSWSQVISRKCFVTNSASSLAIAIDKNFFQPIEHIICLSECDINSDSTISLMKEKLGTRKFNLVLSDMAPNASGIKDIDKHTMNQLNQMALKVAIENSCKGASFLFKMWSDMNSEKHLKDLILRFYKSVKIVKPPASRSDSSEIFLLCQGF 739
            + ++  D +   ++   +R RSAFKLI+L+ K+  L     ++D  AAPG W QV S+  F+    SS+ + +D    +PI+++I  +E DI ++    L+K++L T K + VL+D APN       D  T  +L   ALK+A EN  +G  F+ K++   + +  L  +  + +KSV   KP ASR++S+EIF++CQG+
Sbjct:    7 VGKRRKDKFYHLAKETGYRARSAFKLIQLNRKFGFLQKSRCLIDLCAAPGGWLQVASK--FM--PMSSIIVGVDLVPIKPIKNVITFTE-DITTERCKQLLKKELKTWKADCVLNDGAPNVGTAWVQDAFTQAELTLSALKLACENLKEGGWFITKVFRSKDYQPLLW-VFQQLFKSVHSTKPQASRNESAEIFVVCQGY 200

[Close]

BLAST of Ribosomal RNA large subunit methyltransferase E vs. Ensembl Nematostella
Match: EDO35418 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SLJ2])

HSP 1 Score: 100.523 bits (249), Expect = 1.073e-24
Identity = 65/203 (32.02%), Postives = 105/203 (51.72%), Query Frame = 2

Query:  143 SRQLSDPYVKRSRIESFRCRSAFKLIELDNKYKLLYPGITVLDCGAAPGSWSQVISRKCFV----TNSASSLAIAIDKNFFQPIEHIICLSECDINSDSTISLMKEKLGTRKFNLVLSDMAPNASGIKDIDKHTMNQLNQMALKVAIENSCKGASFLFKMWSDMNSEKHLKDLILRFYKSVKIVKPPASRSDSSEIFLLCQGF 739
            S+   D Y + ++ E +R RSAFKL++L+  + L      V+D  AAPGSWSQV+SRK               +A+D     P+  +I + + DI   ST + +         +LV+ D AP+ +G+ DID++   QL   AL +       G +F+ K++   +       L + F+ +V I KP +SR+ S E F++CQG+
Sbjct:    5 SKDKRDIYYRLAKEEGWRARSAFKLLQLNEDFDLFSGVSKVVDLCAAPGSWSQVLSRKLIEEKQDEEGEKPKIVAVDLQAMAPLPGVIQI-QGDITKTSTANQIISHFEGEHADLVICDGAPDVTGLHDIDEYIQGQLLLAALNITTHVLKPGGNFVAKIFRGKDVSLLYAQLKV-FFPTVTICKPRSSRNSSIESFVVCQGY 205

[Close]

BLAST of Ribosomal RNA large subunit methyltransferase E vs. Ensembl Nematostella
Match: EDO47531 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RM31])

HSP 1 Score: 56.225 bits (134), Expect = 5.007e-9
Identity = 37/101 (36.63%), Postives = 59/101 (58.42%), Query Frame = 2

Query:  437 LMKEKLGTRKFNLVLSDMAPNASGIKDIDKHTMNQLNQMALKVAIENSCKGASFLFKMWSDMNSEKHLKDLILRFYKSVKIVKPPASRSDSSEIFLLCQGF 739
            L+K++L T + + VL+D APN       D  T  +L   ALK+A EN  +G  F+ K++   + +  L  +  + +KSV   KP ASR++S+EIF++CQ  
Sbjct:   19 LLKKELKTWQADCVLNDGAPNVGTAWVQDAFTQAELTLSALKLACENLKEGGWFITKVFRSKDYQPLLW-VFQQLFKSVHSTKPQASRNESAEIFVVCQSL 118

[Close]

BLAST of Ribosomal RNA large subunit methyltransferase E vs. Ensembl Medaka
Match: mrm2 (mitochondrial rRNA methyltransferase 2 [Source:NCBI gene;Acc:101169946])

HSP 1 Score: 152.14 bits (383), Expect = 1.288e-44
Identity = 85/231 (36.80%), Postives = 134/231 (58.01%), Query Frame = 2

Query:   74 LKCKY--VSKLARFFSKGADSNVWLSRQLSDPYVKRSRIESFRCRSAFKLIELDNKYKLLYPGITVLDCGAAPGSWSQVISRKCFVTNSASS-------LAIAIDKNFFQPIEHIICLSECDINSDSTISLMKEKLGTRKFNLVLSDMAPNASGIKDIDKHTMNQLNQMALKVAIENSCKGASFLFKMWSDMNSEKHLKDLILRFYKSVKIVKPPASRSDSSEIFLLCQGF 739
            ++C Y  VS L +   K      W+ RQL DPYVK S  ++FRCRSAFKL+E+D++++LL PG +V+DCGAAPG+WSQV  ++    NSA S       + I ID     P+     L   D+   +T + ++  L + + +++LSDMAPNA+G +D+D   +  +    + +A +    G S L K W  + + + L++ +   + SV+ VKP ASR DS+E + L + +
Sbjct:    1 MRCVYSSVSLLKKQTGKTPAEQRWVQRQLKDPYVKASHSQNFRCRSAFKLLEIDDRFRLLQPGFSVVDCGAAPGAWSQVAVQR---VNSAGSDQDLPRGMVIGIDLLHIPPLAGAHFLPSHDVTDPATHAELQALLPSGQAHVILSDMAPNATGFRDMDHERLVSMCLSLIDLAEKVLLPGGSLLCKYWDGVLAHR-LQEKLSSVFSSVRTVKPDASRKDSAERYFLARMY 227

[Close]

BLAST of Ribosomal RNA large subunit methyltransferase E vs. Ensembl Medaka
Match: ftsj3 (FtsJ RNA 2'-O-methyltransferase 3 [Source:NCBI gene;Acc:101158684])

HSP 1 Score: 112.079 bits (279), Expect = 3.361e-27
Identity = 70/194 (36.08%), Postives = 112/194 (57.73%), Query Frame = 2

Query:  158 DPYVKRSRIESFRCRSAFKLIELDNKYKLLYPGITVLDCGAAPGSWSQVISRKCFVTNSASSLAIAIDKNFFQPIEHIICLSECDINSDSTISLMKEKLGTRKFNLVLSDMAPNASGIKDIDKHTMNQLNQMALKVAIENSCKGASFLFKMWSDMNSEKHLKDLILRFYKSVKIVKPPASRSDSSEIFLLCQGF 739
            D +   ++   +R RS+FKLI+L+ K++ L     ++D  AAPG W QV S+   V    SSL I +D    +PI  ++ L E DI ++     ++++L T K ++VL+D APN       D  +   L  MALK+A E   KG +F+ K++   + +  L  +  +F+K V+  KP ASR++S+EIF++CQGF
Sbjct:   13 DKFYHLAKETGYRSRSSFKLIQLNRKFQFLQKARALVDLCAAPGGWLQVASKFMPV----SSLIIGVDLVPIRPIPSVVTLQE-DITTEKCKQALRKELQTWKVDVVLNDGAPNVGANWQHDAFSQAHLTLMALKLACEFLNKGGTFVTKVFRSKDYQPLLW-IFQQFFKKVQSTKPQASRNESAEIFVVCQGF 200

[Close]

BLAST of Ribosomal RNA large subunit methyltransferase E vs. Ensembl Medaka
Match: ftsj1 (FtsJ RNA 2'-O-methyltransferase 1 [Source:NCBI gene;Acc:101164526])

HSP 1 Score: 97.8265 bits (242), Expect = 2.684e-23
Identity = 63/200 (31.50%), Postives = 103/200 (51.50%), Query Frame = 2

Query:  143 SRQLSDPYVKRSRIESFRCRSAFKLIELDNKYKLLYPGITVLDCGAAPGSWSQVISRKCFVTNSASSLAI-AIDKNFFQPIEHIICLSECDINSDSTISLMKEKLGTRKFNLVLSDMAPNASGIKDIDKHTMNQLNQMALKVAIENSCKGASFLFKMWSDMNSEKHLKDLILRFYKSVKIVKPPASRSDSSEIFLLCQGF 739
            S+   D Y + ++ E +R RSAFKL++LD ++ L       +D  AAPGSWSQV+SRK      A  + I A+D     P+  +  + + DI   ST   +      +  +LV+ D AP+ +G+ D+D++   QL   AL +       G +F+ K++   +       L + F+  V   KP +SR+ S E F++CQ +
Sbjct:    5 SKDKRDIYYRLAKEEGWRARSAFKLLQLDQEFNLFTGVSRAVDLCAAPGSWSQVLSRKLRGDEGAKEVKIVAVDLQAMAPLPGVTQI-QGDITKVSTAQEIIRHFEGQAADLVVCDGAPDVTGLHDVDEYIQAQLLLAALNITTHVLKPGGTFVAKIFRGKDVTLLYSQLKI-FFSRVTCAKPRSSRNSSIESFVVCQRY 202

[Close]

Query:  143 SRQLSDPYVKRSRIESFRCRSAFKLIELDNKYKLLYPGITVLDCGAAPGSWSQVISRKCFVTNSASSLAI-AIDKNFFQPIEHIICLSECDINSDSTISLMKEKLGTRKFNLVLSDMAPNASGIKDIDKHTMNQLNQMALKVAIENSCKGASFLFKMWSDMNSEKHLKDLILRFYKSVKIVKPPASRSDSSEIFLLCQGF 739
            S+   D Y + ++ E +R RSAFKL++LD ++ L       +D  AAPGSWSQV+SRK      A  + I A+D     P+  +  + + DI   ST   +      +  +LV+ D AP+ +G+ D+D++   QL   AL +       G +F+ K++   +       L + F+  V   KP +SR+ S E F++CQ +
Sbjct:    5 SKDKRDIYYRLAKEEGWRARSAFKLLQLDQEFNLFTGVSRAVDLCAAPGSWSQVLSRKLRGDEGAKEVKIVAVDLQAMAPLPGVTQI-QGDITKVSTAQEIIRHFEGQAADLVVCDGAPDVTGLHDVDEYIQAQLLLAALNITTHVLKPGGTFVAKIFRGKDVTLLYSQLKI-FFSRVTCAKPRSSRNSSIESFVVCQRY 202

[Close]

BLAST of Ribosomal RNA large subunit methyltransferase E vs. Ensembl Medaka
Match: ftsj1 (FtsJ RNA 2'-O-methyltransferase 1 [Source:NCBI gene;Acc:101164526])

HSP 1 Score: 81.6481 bits (200), Expect = 2.673e-17
Identity = 51/156 (32.69%), Postives = 81/156 (51.92%), Query Frame = 2

Query:  143 SRQLSDPYVKRSRIESFRCRSAFKLIELDNKYKLLYPGITVLDCGAAPGSWSQVISRKCFVTNSASSLAI-AIDKNFFQPIEHIICLSECDINSDSTISLMKEKLGTRKFNLVLSDMAPNASGIKDIDKHTMNQLNQMALKVAIENSCKGASFLFK 607
            S+   D Y + ++ E +R RSAFKL++LD ++ L       +D  AAPGSWSQV+SRK      A  + I A+D     P+  +  + + DI   ST   +      +  +LV+ D AP+ +G+ D+D++   QL   AL +       G +F+ K
Sbjct:    5 SKDKRDIYYRLAKEEGWRARSAFKLLQLDQEFNLFTGVSRAVDLCAAPGSWSQVLSRKLRGDEGAKEVKIVAVDLQAMAPLPGVTQI-QGDITKVSTAQEIIRHFEGQAADLVVCDGAPDVTGLHDVDEYIQAQLLLAALNITTHVLKPGGTFVAK 159

[Close]

BLAST of Ribosomal RNA large subunit methyltransferase E vs. Planmine SMEST
Match: SMESG000015492.1 (SMESG000015492.1)

HSP 1 Score: 465.692 bits (1197), Expect = 4.361e-168
Identity = 227/228 (99.56%), Postives = 227/228 (99.56%), Query Frame = 2

Query:   62 MFDYLKCKYVSKLARFFSKGADSNVWLSRQLSDPYVKRSRIESFRCRSAFKLIELDNKYKLLYPGITVLDCGAAPGSWSQVISRKCFVTNSASSLAIAIDKNFFQPIEHIICLSECDINSDSTISLMKEKLGTRKFNLVLSDMAPNASGIKDIDKHTMNQLNQMALKVAIENSCKGASFLFKMWSDMNSEKHLKDLILRFYKSVKIVKPPASRSDSSEIFLLCQGFGE 745
            MFDYLKCKYVSKLARFFSKGADSNVWLSRQLSDPYVKRSRIESFRCRSAFKLIELD KYKLLYPGITVLDCGAAPGSWSQVISRKCFVTNSASSLAIAIDKNFFQPIEHIICLSECDINSDSTISLMKEKLGTRKFNLVLSDMAPNASGIKDIDKHTMNQLNQMALKVAIENSCKGASFLFKMWSDMNSEKHLKDLILRFYKSVKIVKPPASRSDSSEIFLLCQGFGE
Sbjct:    1 MFDYLKCKYVSKLARFFSKGADSNVWLSRQLSDPYVKRSRIESFRCRSAFKLIELDTKYKLLYPGITVLDCGAAPGSWSQVISRKCFVTNSASSLAIAIDKNFFQPIEHIICLSECDINSDSTISLMKEKLGTRKFNLVLSDMAPNASGIKDIDKHTMNQLNQMALKVAIENSCKGASFLFKMWSDMNSEKHLKDLILRFYKSVKIVKPPASRSDSSEIFLLCQGFGE 228

[Close]

BLAST of Ribosomal RNA large subunit methyltransferase E vs. Planmine SMEST
Match: SMESG000015492.1 (SMESG000015492.1)

HSP 1 Score: 424.861 bits (1091), Expect = 3.402e-152
Identity = 211/228 (92.54%), Postives = 211/228 (92.54%), Query Frame = 2

Query:   62 MFDYLKCKYVSKLARFFSKGADSNVWLSRQLSDPYVKRSRIESFRCRSAFKLIELDNKYKLLYPGITVLDCGAAPGSWSQVISRKCFVTNSASSLAIAIDKNFFQPIEHIICLSECDINSDSTISLMKEKLGTRKFNLVLSDMAPNASGIKDIDKHTMNQLNQMALKVAIENSCKGASFLFKMWSDMNSEKHLKDLILRFYKSVKIVKPPASRSDSSEIFLLCQGFGE 745
            MFDYLKCKYVSKLARFFSKGADSNVWLSRQLSDPYVKRSRIESFRCRSAFKLIELD KYKLLYPGITVLDCGAAPGSWSQVISRKCFVTNSASSLAIAIDKNFFQPIEHIICLSEC                TRKFNLVLSDMAPNASGIKDIDKHTMNQLNQMALKVAIENSCKGASFLFKMWSDMNSEKHLKDLILRFYKSVKIVKPPASRSDSSEIFLLCQGFGE
Sbjct:    1 MFDYLKCKYVSKLARFFSKGADSNVWLSRQLSDPYVKRSRIESFRCRSAFKLIELDTKYKLLYPGITVLDCGAAPGSWSQVISRKCFVTNSASSLAIAIDKNFFQPIEHIICLSEC----------------TRKFNLVLSDMAPNASGIKDIDKHTMNQLNQMALKVAIENSCKGASFLFKMWSDMNSEKHLKDLILRFYKSVKIVKPPASRSDSSEIFLLCQGFGE 212

[Close]

BLAST of Ribosomal RNA large subunit methyltransferase E vs. Planmine SMEST
Match: SMESG000054113.1 (SMESG000054113.1)

HSP 1 Score: 95.5153 bits (236), Expect = 5.740e-23
Identity = 63/207 (30.43%), Postives = 107/207 (51.69%), Query Frame = 2

Query:  143 SRQLSDPYVKRSRIESFRCRSAFKLIELDNKYKLLYPG----ITVLDCGAAPGSWSQVISRKCFVTNSASSLA----IAIDKNFFQPIEHIICLSECDINSDSTISLMKEKLGTRKFNLVLSDMAPNASGIKDIDKHTMNQLNQMALKVAIENSCKGASFLFKMWSDMNSEKHLKDLILRFYKSVKIVKPPASRSDSSEIFLLCQGF 739
            S+   D Y + ++ E +R RSA+KLI+++ ++ +          V+D  AAPGSWSQV+++K +             +A+D     PI  I  L + DI ++ T + +  +    K  LV+ D AP+ +G+ DID+   +QL   AL +      +G +F+ K++    S+     L L F   V   KP +SR+ S+E F +C+G+
Sbjct:    5 SKDKRDIYYRLAKEEGWRARSAYKLIQINEEFNIFEKDCQSLTRVVDLCAAPGSWSQVLAKKLWEPKPDQERENVKIVAVDLQEMSPIPGIFQL-QGDITNEITANEIITQFQGLKAQLVVCDGAPDVTGLHDIDEFIQHQLVLAALNITTHVLEEGGTFIAKVFRGPESQLLFSQLRLFFPLEVVCAKPKSSRNSSAECFAVCRGY 210

[Close]

BLAST of Ribosomal RNA large subunit methyltransferase E vs. Planmine SMEST
Match: SMESG000054113.1 (SMESG000054113.1)

HSP 1 Score: 95.5153 bits (236), Expect = 1.415e-22
Identity = 63/207 (30.43%), Postives = 107/207 (51.69%), Query Frame = 2

Query:  143 SRQLSDPYVKRSRIESFRCRSAFKLIELDNKYKLLYPG----ITVLDCGAAPGSWSQVISRKCFVTNSASSLA----IAIDKNFFQPIEHIICLSECDINSDSTISLMKEKLGTRKFNLVLSDMAPNASGIKDIDKHTMNQLNQMALKVAIENSCKGASFLFKMWSDMNSEKHLKDLILRFYKSVKIVKPPASRSDSSEIFLLCQGF 739
            S+   D Y + ++ E +R RSA+KLI+++ ++ +          V+D  AAPGSWSQV+++K +             +A+D     PI  I  L + DI ++ T + +  +    K  LV+ D AP+ +G+ DID+   +QL   AL +      +G +F+ K++    S+     L L F   V   KP +SR+ S+E F +C+G+
Sbjct:    5 SKDKRDIYYRLAKEEGWRARSAYKLIQINEEFNIFEKDCQSLTRVVDLCAAPGSWSQVLAKKLWEPKPDQERENVKIVAVDLQEMSPIPGIFQL-QGDITNEITANEIITQFQGLKAQLVVCDGAPDVTGLHDIDEFIQHQLVLAALNITTHVLEEGGTFIAKVFRGPESQLLFSQLRLFFPLEVVCAKPKSSRNSSAECFAVCRGY 210

[Close]

BLAST of Ribosomal RNA large subunit methyltransferase E vs. Planmine SMEST
Match: SMESG000067428.1 (SMESG000067428.1)

HSP 1 Score: 92.4337 bits (228), Expect = 1.427e-20
Identity = 62/191 (32.46%), Postives = 103/191 (53.93%), Query Frame = 2

Query:  158 DPYVKRSRIESFRCRSAFKLIELDNKYKLLYPGITVLDCGAAPGSWSQVISRKCFVTNSASSLAIAIDKNFFQPIEHIICLSECDINSDSTISLMKEKLGTRKFNLVLSDMAPNASGIKDIDKHTMNQLNQMALKVAIENSCKGASFLFKMWSDMNSEKHLKDLILRFYKSVKIVKPPASRSDSSEIFLLC 730
            D Y   ++    R RS+FKLIE++  + +L     ++D  AAPG W Q+ ++    T   SS  I ID    +PI   I + + DI SD    L+K+ +   K +++L D APN     ++D+     L   A  +A E   K  +F+ K++   + E  LK +  + ++ V++VKP +SR++S+EIFL+C
Sbjct:   13 DEYYYMAKNTGLRARSSFKLIEINKLFHILENATILIDLCAAPGGWMQIAAK----TMKKSSFIIGIDLVPIKPIPGTISI-QADITSDKCKQLIKKHILKAKADVILHDGAPNVGANWNVDEFQQAHLCLKAFALATEFLVKNGTFVTKVFRSKDYE-SLKWVFDQLFEKVQVVKPKSSRNESAEIFLVC 197

The following BLAST results are available for this feature:

BLAST of Ribosomal RNA large subunit methyltransferase E vs. Ensembl Human
BLAST of Ribosomal RNA large subunit methyltransferase E vs. Ensembl Celegans
BLAST of Ribosomal RNA large subunit methyltransferase E vs. Ensembl Fly
BLAST of Ribosomal RNA large subunit methyltransferase E vs. Ensembl Zebrafish
BLAST of Ribosomal RNA large subunit methyltransferase E vs. Ensembl Xenopus
BLAST of Ribosomal RNA large subunit methyltransferase E vs. Ensembl Mouse
BLAST of Ribosomal RNA large subunit methyltransferase E vs. UniProt/SwissProt
BLAST of Ribosomal RNA large subunit methyltransferase E vs. TrEMBL
BLAST of Ribosomal RNA large subunit methyltransferase E vs. Ensembl Cavefish
BLAST of Ribosomal RNA large subunit methyltransferase E vs. Ensembl Sea Lamprey
BLAST of Ribosomal RNA large subunit methyltransferase E vs. Ensembl Yeast
BLAST of Ribosomal RNA large subunit methyltransferase E vs. Ensembl Nematostella
BLAST of Ribosomal RNA large subunit methyltransferase E vs. Ensembl Medaka
BLAST of Ribosomal RNA large subunit methyltransferase E vs. Planmine SMEST

BLAST of Ribosomal RNA large subunit methyltransferase E vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5


Match Name	E-value	Identity	Description
MRM2	2.386e-46	38.65	mitochondrial rRNA methyltransferase 2 [Source:HGN...	[more]
MRM2	2.386e-46	38.65	mitochondrial rRNA methyltransferase 2 [Source:HGN...	[more]
FTSJ3	2.454e-25	32.37	FtsJ RNA 2'-O-methyltransferase 3 [Source:HGNC Sym...	[more]
FTSJ1	4.172e-24	31.66	FtsJ RNA 2'-O-methyltransferase 1 [Source:HGNC Sym...	[more]
FTSJ1	4.431e-24	32.50	FtsJ RNA 2'-O-methyltransferase 1 [Source:HGNC Sym...	[more]

BLAST of Ribosomal RNA large subunit methyltransferase E vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 5


Match Name	E-value	Identity	Description
F45G2.9	7.684e-36	35.48	rRNA methyltransferase 2, mitochondrial [Source:U...	[more]
R74.7	2.757e-24	32.14	Putative tRNA (cytidine(32)/guanosine(34)-2'-O)-me...	[more]
H06I04.3	3.928e-22	34.33	rRNA methyltransferase [Source:UniProtKB/TrEMBL;A...	[more]
H06I04.3	7.307e-22	34.33	rRNA methyltransferase [Source:UniProtKB/TrEMBL;A...	[more]
H06I04.3	8.674e-22	34.33	rRNA methyltransferase [Source:UniProtKB/TrEMBL;A...	[more]

BLAST of Ribosomal RNA large subunit methyltransferase E vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 4


Match Name	E-value	Identity	Description
CG11447	3.365e-52	38.72	gene:FBgn0038737 transcript:FBtr0083815	[more]
CG5220	7.377e-28	35.12	gene:FBgn0038471 transcript:FBtr0083391	[more]
CG7009	1.919e-25	32.84	gene:FBgn0038861 transcript:FBtr0084029	[more]
CG8939	1.252e-17	32.54	gene:FBgn0030720 transcript:FBtr0074138	[more]

BLAST of Ribosomal RNA large subunit methyltransferase E vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5


Match Name	E-value	Identity	Description
mrm2	2.771e-44	40.89	mitochondrial rRNA methyltransferase 2 [Source:ZFI...	[more]
ftsj3	1.344e-27	37.50	FtsJ RNA 2'-O-methyltransferase 3 [Source:ZFIN;Acc...	[more]
ftsj3	1.345e-27	37.50	FtsJ RNA 2'-O-methyltransferase 3 [Source:ZFIN;Acc...	[more]
ftsj1	2.709e-24	32.00	FtsJ RNA 2'-O-methyltransferase 1 [Source:ZFIN;Acc...	[more]
ftsj1	2.968e-24	32.00	FtsJ RNA 2'-O-methyltransferase 1 [Source:ZFIN;Acc...	[more]

BLAST of Ribosomal RNA large subunit methyltransferase E vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5


Match Name	E-value	Identity	Description
ankrd13c	4.209e-45	38.39	ankyrin repeat domain 13C [Source:Xenbase;Acc:XB-G...	[more]
FTSJ3	2.549e-26	34.30	FtsJ RNA 2'-O-methyltransferase 3 [Source:NCBI gen...	[more]
FTSJ3	2.350e-25	34.30	FtsJ RNA 2'-O-methyltransferase 3 [Source:NCBI gen...	[more]
FTSJ3	3.071e-25	35.41	FtsJ RNA 2'-O-methyltransferase 3 [Source:NCBI gen...	[more]
FTSJ3	5.662e-21	32.37	FtsJ RNA 2'-O-methyltransferase 3 [Source:NCBI gen...	[more]

BLAST of Ribosomal RNA large subunit methyltransferase E vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5


Match Name	E-value	Identity	Description
Mrm2	2.867e-48	37.04	mitochondrial rRNA methyltransferase 2 [Source:MGI...	[more]
Ftsj3	1.487e-24	32.37	FtsJ RNA methyltransferase homolog 3 (E. coli) [So...	[more]
Ftsj1	2.851e-24	32.66	FtsJ RNA methyltransferase homolog 1 (E. coli) [So...	[more]
Ftsj1	2.880e-24	32.66	FtsJ RNA methyltransferase homolog 1 (E. coli) [So...	[more]
Ftsj1	3.574e-24	32.66	FtsJ RNA methyltransferase homolog 1 (E. coli) [So...	[more]

BLAST of Ribosomal RNA large subunit methyltransferase E vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5


Match Name	E-value	Identity	Description
sp\|Q9VDT6\|MRM2_DROME	3.373e-51	38.72	rRNA methyltransferase 2, mitochondrial OS=Drosoph...	[more]
sp\|Q9CPY0\|MRM2_MOUSE	2.005e-47	37.04	rRNA methyltransferase 2, mitochondrial OS=Mus mus...	[more]
sp\|Q9UI43\|MRM2_HUMAN	1.146e-45	38.65	rRNA methyltransferase 2, mitochondrial OS=Homo sa...	[more]
sp\|A5EHP2\|RLME_BRASB	4.070e-40	37.75	Ribosomal RNA large subunit methyltransferase E OS...	[more]
sp\|Q8P9Y1\|RLME_XANCP	5.113e-40	36.54	Ribosomal RNA large subunit methyltransferase E OS...	[more]

BLAST of Ribosomal RNA large subunit methyltransferase E vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5


Match Name	E-value	Identity	Description
A0A2J7QN05	2.379e-57	46.15	rRNA methyltransferase 2, mitochondrial OS=Cryptot...	[more]
A0A444TDL6	4.826e-57	45.41	rRNA methyltransferase 2, mitochondrial OS=Armadil...	[more]
A0A232FKL9	2.557e-56	44.91	FtsJ domain-containing protein OS=Trichomalopsis s...	[more]
K7IZI4	1.328e-55	43.52	FtsJ domain-containing protein OS=Nasonia vitripen...	[more]
A0A182XJ46	6.422e-55	44.60	FtsJ domain-containing protein OS=Anopheles quadri...	[more]

BLAST of Ribosomal RNA large subunit methyltransferase E vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5


Match Name	E-value	Identity	Description
mrm2	1.187e-46	40.65	mitochondrial rRNA methyltransferase 2 [Source:NCB...	[more]
ftsj3	1.878e-27	35.50	FtsJ RNA 2'-O-methyltransferase 3 [Source:NCBI gen...	[more]
ftsj1	2.248e-23	32.00	FtsJ RNA 2'-O-methyltransferase 1 [Source:NCBI gen...	[more]
ftsj1	2.248e-23	32.00	FtsJ RNA 2'-O-methyltransferase 1 [Source:NCBI gen...	[more]
ftsj1	6.506e-19	30.00	FtsJ RNA 2'-O-methyltransferase 1 [Source:NCBI gen...	[more]

BLAST of Ribosomal RNA large subunit methyltransferase E vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 1


Match Name	E-value	Identity	Description
ftsj1	1.061e-22	31.34	FtsJ RNA 2'-O-methyltransferase 1 [Source:ZFIN;Acc...	[more]

BLAST of Ribosomal RNA large subunit methyltransferase E vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 3


Match Name	E-value	Identity	Description
TRM7	6.417e-27	32.17	2'-O-ribose methyltransferase; methylates the 2'-O...	[more]
SPB1	1.527e-24	35.38	AdoMet-dependent methyltransferase; involved in rR...	[more]
MRM2	2.046e-16	42.50	Mitochondrial 2' O-ribose methyltransferase; requi...	[more]

BLAST of Ribosomal RNA large subunit methyltransferase E vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 4


Match Name	E-value	Identity	Description
EDO44102	7.572e-44	38.54	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO47532	1.129e-28	35.00	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO35418	1.073e-24	32.02	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO47531	5.007e-9	36.63	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]

BLAST of Ribosomal RNA large subunit methyltransferase E vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5


Match Name	E-value	Identity	Description
mrm2	1.288e-44	36.80	mitochondrial rRNA methyltransferase 2 [Source:NCB...	[more]
ftsj3	3.361e-27	36.08	FtsJ RNA 2'-O-methyltransferase 3 [Source:NCBI gen...	[more]
ftsj1	2.684e-23	31.50	FtsJ RNA 2'-O-methyltransferase 1 [Source:NCBI gen...	[more]
ftsj1	2.684e-23	31.50	FtsJ RNA 2'-O-methyltransferase 1 [Source:NCBI gen...	[more]
ftsj1	2.673e-17	32.69	FtsJ RNA 2'-O-methyltransferase 1 [Source:NCBI gen...	[more]

BLAST of Ribosomal RNA large subunit methyltransferase E vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5


Match Name	E-value	Identity	Description
SMESG000015492.1	4.361e-168	99.56	SMESG000015492.1	[more]
SMESG000015492.1	3.402e-152	92.54	SMESG000015492.1	[more]
SMESG000054113.1	5.740e-23	30.43	SMESG000054113.1	[more]
SMESG000054113.1	1.415e-22	30.43	SMESG000054113.1	[more]
SMESG000067428.1	1.427e-20	32.46	SMESG000067428.1	[more]

Analyses

This transcript is derived from or has results from the following analyses


Analysis Name	Date Performed
Embryonic Stages	2016-07-25
Schmidtea mediterranea smed_20140614 BLASTX Human e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL	2020-05-01
Schmidtea mediterranea Sexual smed_20140614 transcriptome	2016-07-25
Schmidtea mediteranean smed_20140614 Interproscan	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST	2020-05-08

Sequences

The following sequences are available for this feature:

transcript sequence
protein sequence

transcript sequence

>SMED30013594 ID=SMED30013594|Name=Ribosomal RNA large subunit methyltransferase E|organism=Schmidtea mediterranea sexual|type=transcript|length=901bp
TTTGAATGTCATTATTATTTATATATAATCTAATATAGTATTAATCTATT
TCTGTTATATAATGTTTGATTATTTAAAATGTAAATATGTTTCTAAATTG
GCTAGATTTTTTAGCAAAGGAGCCGATAGTAACGTGTGGCTTAGTCGGCA
ATTAAGTGACCCTTACGTGAAAAGATCACGAATTGAAAGTTTCAGATGTC
GTAGTGCATTTAAATTGATTGAATTAGACAATAAATATAAACTTTTATAT
CCCGGTATTACTGTTTTAGATTGTGGCGCTGCTCCCGGATCATGGTCACA
AGTAATCTCAAGGAAATGCTTTGTGACTAATTCCGCTTCCTCTCTTGCTA
TAGCTATTGACAAAAATTTTTTCCAGCCAATTGAACATATAATTTGTTTA
TCCGAATGTGATATAAATTCAGATTCCACTATTAGTTTAATGAAAGAAAA
ATTAGGTACAAGAAAATTTAACTTGGTTCTCAGTGACATGGCCCCGAATG
CTAGTGGAATCAAGGATATCGATAAACACACAATGAATCAATTAAATCAA
ATGGCATTAAAGGTGGCGATTGAAAATTCTTGCAAGGGGGCTTCATTTCT
TTTCAAAATGTGGAGTGACATGAACAGCGAAAAGCATTTGAAGGATTTAA
TTCTACGATTTTATAAATCAGTTAAAATTGTAAAGCCTCCTGCTAGTCGT
TCAGACTCATCTGAGATCTTTTTGCTTTGTCAGGGATTTGGTGAATAAAA
TATTAATAATTAACGAGCTATATTCAACACTTCAGGCCGTCAGTTATTTT
ATTAGTTTTTTCTGAGACCCTGTTTAAGATGCTTTCCTACATGTTACTAT
AGAAACTGCACGTTGCTAATTATTAAGCTGTTTAAAAGGGTAAAAAGAAA
T

protein sequence of SMED30013594-orf-1

>SMED30013594-orf-1 ID=SMED30013594-orf-1|Name=SMED30013594-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=229bp
MFDYLKCKYVSKLARFFSKGADSNVWLSRQLSDPYVKRSRIESFRCRSAF
KLIELDNKYKLLYPGITVLDCGAAPGSWSQVISRKCFVTNSASSLAIAID
KNFFQPIEHIICLSECDINSDSTISLMKEKLGTRKFNLVLSDMAPNASGI
KDIDKHTMNQLNQMALKVAIENSCKGASFLFKMWSDMNSEKHLKDLILRF
YKSVKIVKPPASRSDSSEIFLLCQGFGE*

Annotated Terms

The following terms have been associated with this transcript:

Vocabulary: **molecular function**
Term	Definition
GO:0008650	rRNA (uridine-2'-O-)-methyltransferase activity
GO:0008168	methyltransferase activity
GO:0016740	transferase activity

Vocabulary: **biological process**
Term	Definition
GO:0031167	rRNA methylation
GO:0001510	RNA methylation
GO:0032259	methylation
GO:0006364	rRNA processing

Vocabulary: **Planarian Anatomy**
Term	Definition
PLANA:0002109	X1 cell

Vocabulary: **INTERPRO**
Term	Definition
IPR029063	SAM-dependent_MTases
IPR015507	rRNA-MeTfrase_E
IPR002877	rRNA_MeTrfase_FtsJ_dom

Vocabulary: **cellular component**
Term	Definition
GO:0005737	cytoplasm

InterPro

Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01


IPR Term	IPR Description	Source	Source Term	Source Description	Alignment
None	No IPR available	GENE3D	G3DSA:3.40.50.150		coord: 43..228 e-value: 5.4E-52 score: 178.4
None	No IPR available	PANTHER	PTHR10920	RIBOSOMAL RNA METHYLTRANSFERASE	coord: 26..226
IPR015507	Ribosomal RNA large subunit methyltransferase E	PIRSF	PIRSF005461	23S_rRNA_mtase	coord: 13..228 e-value: 4.1E-57 score: 190.8
IPR002877	Ribosomal RNA methyltransferase FtsJ domain	PFAM	PF01728	FtsJ	coord: 44..226 e-value: 3.1E-47 score: 161.0
IPR029063	S-adenosyl-L-methionine-dependent methyltransferase	SUPERFAMILY	SSF53335	S-adenosyl-L-methionine-dependent methyltransferases	coord: 20..227