MICOS complex subunit MIC10

Overview
NameMICOS complex subunit MIC10
Smed IDSMED30013578
Length (bp)466
Neoblast Clusters

Zeng et. al., 2018



▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)



Explore this single cell expression dataset with our NB Cluster Shiny App



 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of MICOS complex subunit MIC10 (SMED30013578) t-SNE clustered cells

Violin plots show distribution of expression levels for MICOS complex subunit MIC10 (SMED30013578) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of MICOS complex subunit MIC10 (SMED30013578) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for MICOS complex subunit MIC10 (SMED30013578) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
Sort Descending | Sort Ascending | Only Non-Zero Values | Tile/Chart | Reset

Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020



SMED30013578

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 2

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
pharynxSMED30013578SMESG000009106.1 dd_Smed_v4_1150_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
parenchymal cellSMED30013578SMESG000009106.1 dd_Smed_v4_1150_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
[Close]
BLAST of MICOS complex subunit MIC10 vs. Ensembl Human
Match: MICOS10 (mitochondrial contact site and cristae organizing system subunit 10 [Source:HGNC Symbol;Acc:HGNC:32068])

HSP 1 Score: 53.9138 bits (128), Expect = 7.015e-10
Identity = 35/74 (47.30%), Postives = 50/74 (67.57%), Query Frame = 2 
Query:   89 TEDELGVKVDRCFSDXXXXXXXXXXXXXXXXFLLFKRKPGIILFSTGIGIGMALANCNNDFKMPCSVVHNQIIK 310
            +E ELG K DRC +DAVVKI  G  +GIV S   FKR+   + F +G+G+GMA +NC +DF+ P  ++H + +K
Sbjct:    2 SESELGRKWDRCLADAVVKIGTGFGLGIVFSLTFFKRRMWPLAFGSGMGLGMAYSNCQHDFQAP-YLLHGKYVK 74
[Close]
BLAST of MICOS complex subunit MIC10 vs. Ensembl Human
Match: MICOS10-NBL1 (MICOS10-NBL1 readthrough [Source:HGNC Symbol;Acc:HGNC:48338])

HSP 1 Score: 45.4394 bits (106), Expect = 1.071e-6
Identity = 31/67 (46.27%), Postives = 45/67 (67.16%), Query Frame = 2 
Query:  110 KVDRCFSDXXXXXXXXXXXXXXXXFLLFKRKPGIILFSTGIGIGMALANCNNDFKMPCSVVHNQIIK 310
            K DRC +DAVVKI  G  +GIV S   FKR+   + F +G+G+GMA +NC +DF+ P  ++H + +K
Sbjct:    2 KWDRCLADAVVKIGTGFGLGIVFSLTFFKRRMWPLAFGSGMGLGMAYSNCQHDFQAP-YLLHGKYVK 67
[Close]
BLAST of MICOS complex subunit MIC10 vs. Ensembl Celegans
Match: F54A3.5 (MICOS complex subunit Mic10 [Source:UniProtKB/Swiss-Prot;Acc:Q9N4K0])

HSP 1 Score: 57.3806 bits (137), Expect = 2.529e-11
Identity = 35/78 (44.87%), Postives = 54/78 (69.23%), Query Frame = 2 
Query:   86 KTEDELGVKVDRCFSDXXXXXXXXXXXXXXXXFLLFKRKPGIILFSTGIGIGMALANCNNDFKMPCSVVHNQIIKAGN 319
            ++EDE+G K+DRCF+D+++K+ GGV+IGIV S   FK +   I F +G+G+G   +NC +DF  P  V+H + + AG 
Sbjct:   12 RSEDEVGQKIDRCFADSLLKVTGGVAIGIVASVAFFKSRSWPIWFGSGVGLGTGWSNCRHDFASPY-VLHGKRVPAGQ 88
[Close]
BLAST of MICOS complex subunit MIC10 vs. Ensembl Zebrafish
Match: micos10 (mitochondrial contact site and cristae organizing system subunit 10 [Source:ZFIN;Acc:ZDB-GENE-060825-325])

HSP 1 Score: 50.0618 bits (118), Expect = 1.387e-8
Identity = 30/62 (48.39%), Postives = 41/62 (66.13%), Query Frame = 2 
Query:   89 TEDELGVKVDRCFSDXXXXXXXXXXXXXXXXFLLFKRKPGIILFSTGIGIGMALANCNNDFK 274
            +E ELG K DRC +D  +K+  G+ +GIV S + FKR+   I   TGIG+GMA +NC ND +
Sbjct:    2 SEKELGQKWDRCLADCAIKVGTGLGLGIVFSVVFFKRRTSPIALGTGIGLGMAYSNCQNDLR 63
[Close]
BLAST of MICOS complex subunit MIC10 vs. Ensembl Mouse
Match: Micos10 (mitochondrial contact site and cristae organizing system subunit 10 [Source:MGI Symbol;Acc:MGI:1913628])

HSP 1 Score: 54.299 bits (129), Expect = 3.034e-10
Identity = 33/74 (44.59%), Postives = 49/74 (66.22%), Query Frame = 2 
Query:   89 TEDELGVKVDRCFSDXXXXXXXXXXXXXXXXFLLFKRKPGIILFSTGIGIGMALANCNNDFKMPCSVVHNQIIK 310
            +E ELG K DRC +D VVK+  G  +GIV S   FKR+   + F +G+G+GMA +NC +DF+ P  ++H + +K
Sbjct:    2 SESELGRKWDRCMADTVVKLGTGFGLGIVFSLTFFKRRMWPLAFGSGVGLGMAYSNCQHDFQAP-YLLHGKYVK 74
[Close]
BLAST of MICOS complex subunit MIC10 vs. UniProt/SwissProt
Match: sp|Q9N4K0|MIC10_CAEEL (MICOS complex subunit Mic10 OS=Caenorhabditis elegans OX=6239 GN=F54A3.5 PE=3 SV=2)

HSP 1 Score: 57.3806 bits (137), Expect = 3.217e-10
Identity = 35/78 (44.87%), Postives = 54/78 (69.23%), Query Frame = 2 
Query:   86 KTEDELGVKVDRCFSDXXXXXXXXXXXXXXXXFLLFKRKPGIILFSTGIGIGMALANCNNDFKMPCSVVHNQIIKAGN 319
            ++EDE+G K+DRCF+D+++K+ GGV+IGIV S   FK +   I F +G+G+G   +NC +DF  P  V+H + + AG 
Sbjct:   12 RSEDEVGQKIDRCFADSLLKVTGGVAIGIVASVAFFKSRSWPIWFGSGVGLGTGWSNCRHDFASPY-VLHGKRVPAGQ 88
[Close]
BLAST of MICOS complex subunit MIC10 vs. UniProt/SwissProt
Match: sp|Q7TNS2|MIC10_MOUSE (MICOS complex subunit Mic10 OS=Mus musculus OX=10090 GN=Micos10 PE=1 SV=1)

HSP 1 Score: 54.299 bits (129), Expect = 2.122e-9
Identity = 33/74 (44.59%), Postives = 49/74 (66.22%), Query Frame = 2 
Query:   89 TEDELGVKVDRCFSDXXXXXXXXXXXXXXXXFLLFKRKPGIILFSTGIGIGMALANCNNDFKMPCSVVHNQIIK 310
            +E ELG K DRC +D VVK+  G  +GIV S   FKR+   + F +G+G+GMA +NC +DF+ P  ++H + +K
Sbjct:    2 SESELGRKWDRCMADTVVKLGTGFGLGIVFSLTFFKRRMWPLAFGSGVGLGMAYSNCQHDFQAP-YLLHGKYVK 74
[Close]
BLAST of MICOS complex subunit MIC10 vs. UniProt/SwissProt
Match: sp|Q5TGZ0|MIC10_HUMAN (MICOS complex subunit MIC10 OS=Homo sapiens OX=9606 GN=MICOS10 PE=1 SV=1)

HSP 1 Score: 53.9138 bits (128), Expect = 3.369e-9
Identity = 35/74 (47.30%), Postives = 50/74 (67.57%), Query Frame = 2 
Query:   89 TEDELGVKVDRCFSDXXXXXXXXXXXXXXXXFLLFKRKPGIILFSTGIGIGMALANCNNDFKMPCSVVHNQIIK 310
            +E ELG K DRC +DAVVKI  G  +GIV S   FKR+   + F +G+G+GMA +NC +DF+ P  ++H + +K
Sbjct:    2 SESELGRKWDRCLADAVVKIGTGFGLGIVFSLTFFKRRMWPLAFGSGMGLGMAYSNCQHDFQAP-YLLHGKYVK 74
[Close]
BLAST of MICOS complex subunit MIC10 vs. UniProt/SwissProt
Match: sp|B2RYW8|MIC10_RAT (MICOS complex subunit Mic10 OS=Rattus norvegicus OX=10116 GN=Micos10 PE=3 SV=1)

HSP 1 Score: 52.7582 bits (125), Expect = 9.283e-9
Identity = 31/74 (41.89%), Postives = 49/74 (66.22%), Query Frame = 2 
Query:   89 TEDELGVKVDRCFSDXXXXXXXXXXXXXXXXFLLFKRKPGIILFSTGIGIGMALANCNNDFKMPCSVVHNQIIK 310
            +E E G K DRC +DA+VK+  G  +G+V S   FKR+   + F +G+G+GMA +NC +DF+ P  ++H + +K
Sbjct:    2 SESEPGRKWDRCMADALVKLGTGFGLGMVFSLTFFKRRKWPLAFGSGVGLGMAYSNCQHDFQAP-YLLHGKYVK 74
[Close]
BLAST of MICOS complex subunit MIC10 vs. TrEMBL
Match: A0A2H1CGL8 (MICOS complex subunit MIC10 OS=Fasciola hepatica OX=6192 GN=D915_06072 PE=3 SV=1)

HSP 1 Score: 69.707 bits (169), Expect = 8.586e-13
Identity = 38/76 (50.00%), Postives = 56/76 (73.68%), Query Frame = 2 
Query:   77 DKVKTEDELGVKVDRCFSDXXXXXXXXXXXXXXXXFLLFKRKPGIILFSTGIGIGMALANCNNDFKMPCSVVHNQI 304
            D  K+ED LG+++DRC SD ++K   G  IGI+ S LL KR+P  ++F TG+G+GM+++NCNNDFK P  +V ++I
Sbjct:    3 DGPKSEDVLGLRLDRCISDTLIKAGSGAFIGIIFSVLLAKRRPWPVVFGTGLGLGMSISNCNNDFKQPLPLVTHRI 78
[Close]
BLAST of MICOS complex subunit MIC10 vs. TrEMBL
Match: A0A4S2MC44 (MICOS complex subunit MIC10 OS=Opisthorchis felineus OX=147828 GN=CRM22_002416 PE=3 SV=1)

HSP 1 Score: 68.9366 bits (167), Expect = 2.101e-12
Identity = 40/74 (54.05%), Postives = 55/74 (74.32%), Query Frame = 2 
Query:   83 VKTEDELGVKVDRCFSDXXXXXXXXXXXXXXXXFLLFKRKPGIILFSTGIGIGMALANCNNDFKMPCSVVHNQI 304
            VK+ED LG + DRC SD ++K A G++IGI+ S LL KR+P  ++F  G+GIGM +ANCNNDFK P  +V ++I
Sbjct:    5 VKSEDILGHRWDRCQSDTIIKTASGITIGIIVSVLLAKRRPWPVIFGAGVGIGMGVANCNNDFKQPLPLVSHRI 78
[Close]
BLAST of MICOS complex subunit MIC10 vs. TrEMBL
Match: A0A183BGC3 (MICOS complex subunit MIC10 OS=Echinostoma caproni OX=27848 GN=ECPE_LOCUS18258 PE=3 SV=1)

HSP 1 Score: 68.5514 bits (166), Expect = 3.030e-12
Identity = 37/76 (48.68%), Postives = 55/76 (72.37%), Query Frame = 2 
Query:   77 DKVKTEDELGVKVDRCFSDXXXXXXXXXXXXXXXXFLLFKRKPGIILFSTGIGIGMALANCNNDFKMPCSVVHNQI 304
            +  K+ED LG+++DRC SD ++K   G  +GI+ S LL K KP  ++F TG+G+GM++ANCNNDFK P  +V ++I
Sbjct:    3 NSAKSEDILGLRLDRCISDTLIKTGSGAFMGIIFSVLLAKSKPWPVVFGTGLGLGMSIANCNNDFKQPLPLVSHRI 78
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BLAST of MICOS complex subunit MIC10 vs. TrEMBL
Match: Q5BSC7 (MICOS complex subunit MIC10 OS=Schistosoma japonicum OX=6182 GN=EWB00_004079 PE=2 SV=1)

HSP 1 Score: 68.5514 bits (166), Expect = 3.618e-12
Identity = 36/79 (45.57%), Postives = 55/79 (69.62%), Query Frame = 2 
Query:   77 DKVKTEDELGVKVDRCFSDXXXXXXXXXXXXXXXXFLLFKRKPGIILFSTGIGIGMALANCNNDFKMPCSVVHNQIIKA 313
            D +K+ED LG K+DRC SD ++K   G+  GI+ S +  KR+P  ++F TG G+GM ++NCNNDFK P  +V ++I+ +
Sbjct:    3 DNLKSEDILGFKLDRCISDTLIKTGAGLFGGIIFSVVFAKRRPWPLIFGTGFGLGMGISNCNNDFKQPLPLVSHRIVSS 81
[Close]
BLAST of MICOS complex subunit MIC10 vs. TrEMBL
Match: A0A146MHV0 (MICOS complex subunit MIC10 OS=Schistosoma mansoni OX=6183 GN=c797_g1_i1 PE=3 SV=1)

HSP 1 Score: 68.1662 bits (165), Expect = 4.072e-12
Identity = 36/79 (45.57%), Postives = 56/79 (70.89%), Query Frame = 2 
Query:   77 DKVKTEDELGVKVDRCFSDXXXXXXXXXXXXXXXXFLLFKRKPGIILFSTGIGIGMALANCNNDFKMPCSVVHNQIIKA 313
            + +K+ED LG K+DRC SD ++K   G+  GI+ S +L KR+P  ++F TG G+GM ++NCNNDFK P  +V ++I+ +
Sbjct:    3 EDLKSEDILGFKLDRCISDTLIKTGAGLFGGIIFSVVLAKRRPWPLIFGTGFGLGMGISNCNNDFKQPLPLVSHRIVSS 81
[Close]
BLAST of MICOS complex subunit MIC10 vs. Ensembl Cavefish
Match: micos10 (MICOS complex subunit MIC10 [Source:NCBI gene;Acc:103047888])

HSP 1 Score: 54.6842 bits (130), Expect = 2.031e-10
Identity = 35/74 (47.30%), Postives = 48/74 (64.86%), Query Frame = 2 
Query:   89 TEDELGVKVDRCFSDXXXXXXXXXXXXXXXXFLLFKRKPGIILFSTGIGIGMALANCNNDFKMPCSVVHNQIIK 310
            +E ELG K DRC +DA +K+  G+ +GIV S + FKR+   I F TG G+GMA +NC ND + P  +VH+   K
Sbjct:    2 SEKELGQKWDRCLADAAIKVGAGLGLGIVFSVVFFKRRTFPIAFGTGTGLGMAYSNCQNDLRSP-YLVHSNATK 74
[Close]
BLAST of MICOS complex subunit MIC10 vs. Ensembl Cavefish
Match: ENSAMXT00000030462.1 (pep primary_assembly:Astyanax_mexicanus-2.0:22:18042672:18051540:1 gene:ENSAMXG00000040088.1 transcript:ENSAMXT00000030462.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 53.1434 bits (126), Expect = 8.695e-10
Identity = 31/72 (43.06%), Postives = 46/72 (63.89%), Query Frame = 2 
Query:   95 DELGVKVDRCFSDXXXXXXXXXXXXXXXXFLLFKRKPGIILFSTGIGIGMALANCNNDFKMPCSVVHNQIIK 310
            ++ G K DRC SD+ VK   G+ +G + S L FKR+   I F  G+G+GMA +NC +DFK P  ++H  ++K
Sbjct:    2 EDSGRKWDRCVSDSAVKTVLGLGVGALFSVLFFKRRSWPIAFGAGMGLGMAYSNCQHDFKSPY-LLHGHMVK 72
[Close]
BLAST of MICOS complex subunit MIC10 vs. Ensembl Medaka
Match: ENSORLT00000027538.1 (mitochondrial contact site and cristae organizing system subunit 10 [Source:NCBI gene;Acc:101167281])

HSP 1 Score: 53.9138 bits (128), Expect = 1.968e-9
Identity = 30/75 (40.00%), Postives = 46/75 (61.33%), Query Frame = 2 
Query:   86 KTEDELGVKVDRCFSDXXXXXXXXXXXXXXXXFLLFKRKPGIILFSTGIGIGMALANCNNDFKMPCSVVHNQIIK 310
            K  DE G K DRC +D  VK   G+ +G+V S L  KR+   + F +G+G+GM  +NC +DF++P   +H + +K
Sbjct:   77 KMADEYGRKWDRCLADTAVKTVTGLGVGVVFSVLFLKRRTWPVSFGSGLGLGMGYSNCQHDFRLPYR-IHGRTVK 150
[Close]
BLAST of MICOS complex subunit MIC10 vs. Ensembl Medaka
Match: ENSORLT00000035437.1 (pep primary_assembly:ASM223467v1:7:1586357:1587485:1 gene:ENSORLG00000024698.1 transcript:ENSORLT00000035437.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 50.0618 bits (118), Expect = 1.402e-8
Identity = 32/63 (50.79%), Postives = 42/63 (66.67%), Query Frame = 2 
Query:   89 TEDELGVKVDRCFSDXXXXXXXXXXXXXXXXFLLFKRKPGIILFSTGIGIGMALANCNNDFKM 277
            +E ELG K+DRC +D V+K+  G+ +GIV S L FKR    I F +G G+GMA ANC ND + 
Sbjct:    2 SERELGRKLDRCLADGVIKLGTGLGLGIVFSVLFFKRHAWPISFGSGAGLGMAYANCQNDLRW 64
[Close]
BLAST of MICOS complex subunit MIC10 vs. Planmine SMEST
Match: SMESG000009106.1 (SMESG000009106.1)

HSP 1 Score: 131.724 bits (330), Expect = 1.082e-40
Identity = 82/82 (100.00%), Postives = 82/82 (100.00%), Query Frame = 2 
Query:   74 MDKVKTEDELGVKVDRCFSDXXXXXXXXXXXXXXXXFLLFKRKPGIILFSTGIGIGMALANCNNDFKMPCSVVHNQIIKAGN 319
            MDKVKTEDELGVKVDRCFSDAVVKIAGGVSIGIVGSFLLFKRKPGIILFSTGIGIGMALANCNNDFKMPCSVVHNQIIKAGN
Sbjct:    1 MDKVKTEDELGVKVDRCFSDAVVKIAGGVSIGIVGSFLLFKRKPGIILFSTGIGIGMALANCNNDFKMPCSVVHNQIIKAGN 82
[Close]
BLAST of MICOS complex subunit MIC10 vs. Planmine SMEST
Match: SMESG000009106.1 (SMESG000009106.1)

HSP 1 Score: 125.176 bits (313), Expect = 3.643e-38
Identity = 81/82 (98.78%), Postives = 81/82 (98.78%), Query Frame = 2 
Query:   74 MDKVKTEDELGVKVDRCFSDXXXXXXXXXXXXXXXXFLLFKRKPGIILFSTGIGIGMALANCNNDFKMPCSVVHNQIIKAGN 319
            MDKVKTEDELGVKVDRCFSDAVVKIAGGVSIGIVGSFLLFKRKPGIILFSTGIGIGMALANCNNDFKMPCSVVHNQII AGN
Sbjct:    1 MDKVKTEDELGVKVDRCFSDAVVKIAGGVSIGIVGSFLLFKRKPGIILFSTGIGIGMALANCNNDFKMPCSVVHNQII-AGN 81
[Close]
BLAST of MICOS complex subunit MIC10 vs. Planmine SMEST
Match: SMESG000039213.1 (SMESG000039213.1)

HSP 1 Score: 72.0182 bits (175), Expect = 1.279e-16
Identity = 37/76 (48.68%), Postives = 54/76 (71.05%), Query Frame = 2 
Query:   83 VKTEDELGVKVDRCFSDXXXXXXXXXXXXXXXXFLLFKRKPGIILFSTGIGIGMALANCNNDFKMPCSVVHNQIIK 310
             K ++ELG+K+DRC SD  +K   G  +G+V S + FKR+PG ++F + +G+GMA+ANCNND K P S+V  +I K
Sbjct:    3 AKIDEELGMKIDRCISDGFIKTIVGAGVGVVASVMFFKRRPGPLIFGSALGLGMAIANCNNDLKQPLSLVSGKIHK 78
The following BLAST results are available for this feature:
BLAST of MICOS complex subunit MIC10 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 2
Match NameE-valueIdentityDescription
MICOS107.015e-1047.30mitochondrial contact site and cristae organizing ... [more]
MICOS10-NBL11.071e-646.27MICOS10-NBL1 readthrough [Source:HGNC Symbol;Acc:H... [more]
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BLAST of MICOS complex subunit MIC10 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 1
Match NameE-valueIdentityDescription
F54A3.52.529e-1144.87MICOS complex subunit Mic10 [Source:UniProtKB/Swi... [more]
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BLAST of MICOS complex subunit MIC10 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of MICOS complex subunit MIC10 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 1
Match NameE-valueIdentityDescription
micos101.387e-848.39mitochondrial contact site and cristae organizing ... [more]
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BLAST of MICOS complex subunit MIC10 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of MICOS complex subunit MIC10 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 1
Match NameE-valueIdentityDescription
Micos103.034e-1044.59mitochondrial contact site and cristae organizing ... [more]
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BLAST of MICOS complex subunit MIC10 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 4
Match NameE-valueIdentityDescription
sp|Q9N4K0|MIC10_CAEEL3.217e-1044.87MICOS complex subunit Mic10 OS=Caenorhabditis eleg... [more]
sp|Q7TNS2|MIC10_MOUSE2.122e-944.59MICOS complex subunit Mic10 OS=Mus musculus OX=100... [more]
sp|Q5TGZ0|MIC10_HUMAN3.369e-947.30MICOS complex subunit MIC10 OS=Homo sapiens OX=960... [more]
sp|B2RYW8|MIC10_RAT9.283e-941.89MICOS complex subunit Mic10 OS=Rattus norvegicus O... [more]
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BLAST of MICOS complex subunit MIC10 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
A0A2H1CGL88.586e-1350.00MICOS complex subunit MIC10 OS=Fasciola hepatica O... [more]
A0A4S2MC442.101e-1254.05MICOS complex subunit MIC10 OS=Opisthorchis feline... [more]
A0A183BGC33.030e-1248.68MICOS complex subunit MIC10 OS=Echinostoma caproni... [more]
Q5BSC73.618e-1245.57MICOS complex subunit MIC10 OS=Schistosoma japonic... [more]
A0A146MHV04.072e-1245.57MICOS complex subunit MIC10 OS=Schistosoma mansoni... [more]
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BLAST of MICOS complex subunit MIC10 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 2
Match NameE-valueIdentityDescription
micos102.031e-1047.30MICOS complex subunit MIC10 [Source:NCBI gene;Acc:... [more]
ENSAMXT00000030462.18.695e-1043.06pep primary_assembly:Astyanax_mexicanus-2.0:22:180... [more]
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BLAST of MICOS complex subunit MIC10 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of MICOS complex subunit MIC10 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of MICOS complex subunit MIC10 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of MICOS complex subunit MIC10 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 2
Match NameE-valueIdentityDescription
ENSORLT00000027538.11.968e-940.00mitochondrial contact site and cristae organizing ... [more]
ENSORLT00000035437.11.402e-850.79pep primary_assembly:ASM223467v1:7:1586357:1587485... [more]
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BLAST of MICOS complex subunit MIC10 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 3
Match NameE-valueIdentityDescription
SMESG000009106.11.082e-40100.00SMESG000009106.1[more]
SMESG000009106.13.643e-3898.78SMESG000009106.1[more]
SMESG000039213.11.279e-1648.68SMESG000039213.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30013578 ID=SMED30013578|Name=MICOS complex subunit MIC10|organism=Schmidtea mediterranea sexual|type=transcript|length=466bp
TATTTTTTCAATAATATTTTGATAAATTACAAAGTTTGTTTAAAAACAGC
CGTTATTTAAATTTAGGTTTTCTATGGATAAAGTTAAAACTGAAGATGAA
CTTGGAGTTAAGGTCGATAGATGCTTTTCGGATGCTGTAGTGAAAATCGC
TGGTGGTGTTAGCATAGGTATAGTTGGTTCATTTTTGTTATTTAAGCGTA
AACCAGGAATAATATTATTTTCGACTGGTATCGGGATTGGAATGGCTTTA
GCAAATTGCAATAATGATTTCAAAATGCCTTGTTCAGTAGTACATAACCA
AATCATAAAGGCTGGTAATTAAAGGGTCTTTGGAAAATTAGGATACTTAA
AGTCTAGAATGTTAATTTGGATTTTATAATAAATGAGCATATTTTATTTA
ATGTTGGTATAAGAATAATAACCTAAATTTGATTATTGAATTTTATATTC
AAACGTTTGATTTTTA
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000016pharynx
Vocabulary: INTERPRO
TermDefinition
IPR007512Mic10
Vocabulary: cellular component
TermDefinition
GO:0005739mitochondrion
GO:0005743mitochondrial inner membrane
GO:0016020membrane
GO:0016021integral component of membrane
GO:0061617MICOS complex
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR007512MICOS complex subunit Mic10PFAMPF04418DUF543coord: 5..67
e-value: 1.3E-15
score: 57.1
IPR007512MICOS complex subunit Mic10PANTHERPTHR21304UNCHARACTERIZEDcoord: 6..79
NoneNo IPR availablePANTHERPTHR21304:SF5MICOS COMPLEX SUBUNIT MIC10coord: 6..79
NoneNo IPR availableTMHMMTMhelixcoord: 21..40
NoneNo IPR availableTMHMMTMhelixcoord: 45..62