Serine/threonine-protein kinase 10
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Overview
Neoblast Clusters
Zeng et. al., 2018▻ Overview▻ Neoblast Population▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Overview
Single cell RNA-seq of pluripotent neoblasts and its early progeniesWe isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)Explore this single cell expression dataset with our NB Cluster Shiny App
Neoblast Population
Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Embryonic Expression
Davies et. al., 2017
Hover the mouse over a column in the graph to view average RPKM values per sample. Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult. back to top Anatomical Expression
PAGE et. al., 2020SMED30013563 has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGEPAGE Curations: 13Note: Hover over icons to view figure legend
Homology
BLAST of Serine/threonine-protein kinase 10 vs. Ensembl Human
Match: STK10 (serine/threonine kinase 10 [Source:HGNC Symbol;Acc:HGNC:11388]) HSP 1 Score: 340.117 bits (871), Expect = 8.902e-101 Identity = 152/297 (51.18%), Postives = 208/297 (70.03%), Query Frame = 3
Query: 87 MAF--IRDLFKRFKANDPKTKKSYSYLNK-CDPNEVWDVIGEIGDGAFGKVFKAKNKSTDDIAALKQVNLEEEGDLEEYIVEIEILTECKHANVVNLYNAYHFESKLWMALEYCNGGALDSLMITLDKNLNEKAIKYTSKEILSGLIFLHTNGVIHRDMKAGNVLVSKDADVKLADFGVSAKLAADKQKRNTVQGTPYWMAPEVIACQNM-ESYYDCRADIWSFGITLMELAQMRPPYHQMQPTRVLIKIAKADPPTLDRPSLWSSAFISFLKRCLTKKPEDRPHGPDLLSDPFIVS 965
MAF R + R + + + Y ++ + DPNEVW+++GE+GDGAFGKV+KAKNK T +AA K + + E +LE+YIVEIEIL C H +V L AY+ + KLW+ +E+C GGA+D++M+ LD+ L E I+ +++L L FLH+ +IHRD+KAGNVL++ + D++LADFGVSAK QKR++ GTPYWMAPEV+ C+ M ++ YD +ADIWS GITL+E+AQ+ PP+H++ P RVL+KIAK+DPPTL PS WS F FLK L K PE RP LL PF+ S
Sbjct: 1 MAFANFRRIL-RLSTFEKRKSREYEHVRRDLDPNEVWEIVGELGDGAFGKVYKAKNKETGALAAAKVIETKSEEELEDYIVEIEILATCDHPYIVKLLGAYYHDGKLWIMIEFCPGGAVDAIMLELDRGLTEPQIQVVCRQMLEALNFLHSKRIIHRDLKAGNVLMTLEGDIRLADFGVSAKNLKTLQKRDSFIGTPYWMAPEVVMCETMKDTPYDYKADIWSLGITLIEMAQIEPPHHELNPMRVLLKIAKSDPPTLLTPSKWSVEFRDFLKIALDKNPETRPSAAQLLEHPFVSS 296 HSP 2 Score: 102.449 bits (254), Expect = 1.740e-21 Identity = 95/342 (27.78%), Postives = 179/342 (52.34%), Query Frame = 3
Query: 1395 SDIKDNESVEKFSIKDEDSDKESNAQAILNRKKSFYKTMTKTRKFIVDGEEITTTTTKVVREGLENKNRDQIQDRKMEIRELQLLAKEESREKRQLQFKMLSERDNLASRQKSDELTFEKSHETEMDNLNKLHKSKLENLENQNYHELTNYQKRLLADKAKKENDFKNK---EKTEFGKELDRLPKHQKRENGKKLRDNNNIIFQEKFKAFQDQLMKDIEEKCESMTATHRLKICELELSLMKEKHQKLSKYNKEKANLEMD--QCQSSYQLENQQKKEMFMLGKSQVKHRQEKEIEHLEKNNKKELDELDYIQQNEKKTFPRFIKNTSRTRNIQKKAELEI 2405
+D+ N+ + SIKD K + KT+ +TRKF+VDG E++ TT+K++ E E K+ + R+ E+REL+LL KEE R + QL K + + + R + + +K +TE++NL + K ++E +E + +R+ ++ + F+ + K E E+++LP+ Q++E+ K+ + + Q + F + +D+E + +T +R +IC+ E + +K + L ++E A EM+ Q Q +QL QQ K+ + L + ++ + EKE E +++ N++ +++L QQ EK P+ ++ +TR K L I
Sbjct: 504 TDLSLNKEMGSLSIKD---------------PKLYKKTLKRTRKFVVDGVEVSITTSKIISED-EKKDEEMRFLRRQELRELRLLQKEEHRNQTQLSNKHELQLEQMHKRFEQEINAKKKFFDTELENLERQQKQQVEKMEQDHAVRRREEARRIRLEQDRDYTRFQEQLKLMKKEVKNEVEKLPRQQRKESMKQKMEEHTQKKQLLDRDFVAKQKEDLELAMKRLTTDNRREICDKERECLMKKQELLR--DREAALWEMEEHQLQERHQLVKQQLKDQYFLQRHELLRKHEKEREQMQRYNQRMIEQLKVRQQQEKARLPKIQRSEGKTRMAMYKKSLHI 827
BLAST of Serine/threonine-protein kinase 10 vs. Ensembl Human
Match: SLK (STE20 like kinase [Source:HGNC Symbol;Acc:HGNC:11088]) HSP 1 Score: 330.102 bits (845), Expect = 1.384e-95 Identity = 143/294 (48.64%), Postives = 209/294 (71.09%), Query Frame = 3
Query: 87 MAFIRDLFKRFKANDPKTKKSYSYLNK-CDPNEVWDVIGEIGDGAFGKVFKAKNKSTDDIAALKQVNLEEEGDLEEYIVEIEILTECKHANVVNLYNAYHFESKLWMALEYCNGGALDSLMITLDKNLNEKAIKYTSKEILSGLIFLHTNGVIHRDMKAGNVLVSKDADVKLADFGVSAKLAADKQKRNTVQGTPYWMAPEVIACQ-NMESYYDCRADIWSFGITLMELAQMRPPYHQMQPTRVLIKIAKADPPTLDRPSLWSSAFISFLKRCLTKKPEDRPHGPDLLSDPFIV 962
M+F + K FK K KK Y ++ + +P + W++IGE+GDGAFGKV+KA+NK T +AA K ++ + E +LE+Y+VEI+IL C H N+V L +A+++E+ LW+ +E+C GGA+D++M+ L++ L E I+ K+ L L +LH N +IHRD+KAGN+L + D D+KLADFGVSAK Q+R++ GTPYWMAPEV+ C+ + + YD +AD+WS GITL+E+A++ PP+H++ P RVL+KIAK++PPTL +PS WSS F FLK+CL K + R LL PF+
Sbjct: 1 MSFF-NFRKIFKLGSEKKKKQYEHVKRDLNPEDFWEIIGELGDGAFGKVYKAQNKETSVLAAAKVIDTKSEEELEDYMVEIDILASCDHPNIVKLLDAFYYENNLWILIEFCAGGAVDAVMLELERPLTESQIQVVCKQTLDALNYLHDNKIIHRDLKAGNILFTLDGDIKLADFGVSAKNTRTIQRRDSFIGTPYWMAPEVVMCETSKDRPYDYKADVWSLGITLIEMAEIEPPHHELNPMRVLLKIAKSEPPTLAQPSRWSSNFKDFLKKCLEKNVDARWTTSQLLQHPFVT 293 HSP 2 Score: 101.679 bits (252), Expect = 3.671e-21 Identity = 97/341 (28.45%), Postives = 172/341 (50.44%), Query Frame = 3
Query: 1395 SDIKDNESVEKFSIKDEDSDKESNAQAILNRKKSFYKTMTKTRKFIVDGEEITTTTTKVVREGLENKNRDQIQDRKMEIRELQLLAKEESREKRQLQFKMLSERDNLASRQKSDELTFEKSHETEMDNLNKLHKSKLENLENQNYHELTNYQKRLLADKAKKENDFKNKEKTEFGKELDRLPKHQKRENGKKLRDNNNIIFQEKFKAFQDQLMKDIEEKC----ESMTATHRLKICELELSLMKEKHQKLSKYNKEKANLEMDQCQSSYQLENQQKKEMFMLGKSQVKHRQEKEIEHLEKNNKKELDELDYIQQNEKKTFPRFIKNTSRTRNIQKKAELEI 2405
S I N S+ F K +DS S L + KT+ KTRKFIVDG E++ TT+K+V + ++K + R+ E+REL+ L KEE R ++QL K+ +R+ + R + + ++ ++ ++ E++NL K K +E LE ++ + L + KR+ ++ K+ + F+N K +E + + K Q+ +G + II Q+K + + +IE +C + + I ELE ++EKHQ L QQ K+ + + + Q+ R EKE E +++ N++ ++EL Q E+ P+ ++ ++TR K L I
Sbjct: 759 SSIDLNLSISSFLSKTKDSGSIS-----LQETRRQKKTLKKTRKFIVDGVEVSVTTSKIVTDS-DSKTEELRFLRRQELRELRFLQKEEQRAQQQLNSKLQQQREQIFRRFEQEMMSKKRQYDQEIENLEKQQKQTIERLEQEHTNRLRDEAKRIKGEQEKELSKFQNMLKNRKKEEQEFVQKQQQELDGSLKK----IIQQQKAE------LANIERECLNNKQQLMRAREAAIWELEERHLQEKHQLL----------------------KQQLKDQYFMQRHQLLKRHEKETEQMQRYNQRLIEELKNRQTQERARLPKIQRSEAKTRMAMFKKSLRI 1061
BLAST of Serine/threonine-protein kinase 10 vs. Ensembl Human
Match: SLK (STE20 like kinase [Source:HGNC Symbol;Acc:HGNC:11088]) HSP 1 Score: 330.102 bits (845), Expect = 1.678e-95 Identity = 143/294 (48.64%), Postives = 209/294 (71.09%), Query Frame = 3
Query: 87 MAFIRDLFKRFKANDPKTKKSYSYLNK-CDPNEVWDVIGEIGDGAFGKVFKAKNKSTDDIAALKQVNLEEEGDLEEYIVEIEILTECKHANVVNLYNAYHFESKLWMALEYCNGGALDSLMITLDKNLNEKAIKYTSKEILSGLIFLHTNGVIHRDMKAGNVLVSKDADVKLADFGVSAKLAADKQKRNTVQGTPYWMAPEVIACQ-NMESYYDCRADIWSFGITLMELAQMRPPYHQMQPTRVLIKIAKADPPTLDRPSLWSSAFISFLKRCLTKKPEDRPHGPDLLSDPFIV 962
M+F + K FK K KK Y ++ + +P + W++IGE+GDGAFGKV+KA+NK T +AA K ++ + E +LE+Y+VEI+IL C H N+V L +A+++E+ LW+ +E+C GGA+D++M+ L++ L E I+ K+ L L +LH N +IHRD+KAGN+L + D D+KLADFGVSAK Q+R++ GTPYWMAPEV+ C+ + + YD +AD+WS GITL+E+A++ PP+H++ P RVL+KIAK++PPTL +PS WSS F FLK+CL K + R LL PF+
Sbjct: 1 MSFF-NFRKIFKLGSEKKKKQYEHVKRDLNPEDFWEIIGELGDGAFGKVYKAQNKETSVLAAAKVIDTKSEEELEDYMVEIDILASCDHPNIVKLLDAFYYENNLWILIEFCAGGAVDAVMLELERPLTESQIQVVCKQTLDALNYLHDNKIIHRDLKAGNILFTLDGDIKLADFGVSAKNTRTIQRRDSFIGTPYWMAPEVVMCETSKDRPYDYKADVWSLGITLIEMAEIEPPHHELNPMRVLLKIAKSEPPTLAQPSRWSSNFKDFLKKCLEKNVDARWTTSQLLQHPFVT 293 HSP 2 Score: 106.686 bits (265), Expect = 1.240e-22 Identity = 92/340 (27.06%), Postives = 176/340 (51.76%), Query Frame = 3
Query: 1395 SDIKDNESVEKFSIKDEDSDKESNAQAILNRKKSFYKTMTKTRKFIVDGEEITTTTTKVVREGLENKNRDQIQDRKMEIRELQLLAKEESREKRQLQFKMLSERDNLASRQKSDELTFEKSHETEMDNLNKLHKSKLENLENQNYHELTNYQKRLLADKAKKENDFKN---KEKTEFGKELDRLPKHQKRENGKKLRDNNNIIFQEKFKAFQDQLMKDIEEKCESMTATHRLKICELELSLMKEKHQKLSKYNKEKANLEMDQCQSSYQLENQQKKEMFMLGKSQVKHRQEKEIEHLEKNNKKELDELDYIQQNEKKTFPRFIKNTSRTRNIQKKAELEI 2405
S I N S+ F K +DS S L + KT+ KTRKFIVDG E++ TT+K+V + ++K + R+ E+REL+ L KEE R ++QL K+ +R+ + R + + ++ ++ ++ E++NL K K +E LE ++ + L + KR+ ++ K+ + F+N K E E+++ PK ++E K+ ++ + + F + ++++ + + + ++ +E + K Q + LE Q +QL QQ K+ + + + Q+ R EKE E +++ N++ ++EL Q E+ P+ ++ ++TR K L I
Sbjct: 759 SSIDLNLSISSFLSKTKDSGSIS-----LQETRRQKKTLKKTRKFIVDGVEVSVTTSKIVTDS-DSKTEELRFLRRQELRELRFLQKEEQRAQQQLNSKLQQQREQIFRRFEQEMMSKKRQYDQEIENLEKQQKQTIERLEQEHTNRLRDEAKRIKGEQEKELSKFQNMLKNRKKEVINEVEKAPKELRKELMKRRKEELAQSQHAQEQEFVQKQQQELDGSLKKIIQQQKAELANIERECLNNKQQLMRAREAAIWELEERHLQEKHQLLKQQLKDQYFMQRHQLLKRHEKETEQMQRYNQRLIEELKNRQTQERARLPKIQRSEAKTRMAMFKKSLRI 1092
BLAST of Serine/threonine-protein kinase 10 vs. Ensembl Human
Match: STK4 (serine/threonine kinase 4 [Source:HGNC Symbol;Acc:HGNC:11408]) HSP 1 Score: 246.514 bits (628), Expect = 1.619e-71 Identity = 118/265 (44.53%), Postives = 163/265 (61.51%), Query Frame = 3
Query: 174 PNEVWDVIGEIGDGAFGKVFKAKNKSTDDIAALKQVNLEEEGDLEEYIVEIEILTECKHANVVNLYNAYHFESKLWMALEYCNGGALDSLMITLDKNLNEKAIKYTSKEILSGLIFLHTNGVIHRDMKAGNVLVSKDADVKLADFGVSAKLAADKQKRNTVQGTPYWMAPEVIACQNMESYYDCRADIWSFGITLMELAQMRPPYHQMQPTRVLIKIAKADPPTLDRPSLWSSAFISFLKRCLTKKPEDRPHGPDLLSDPFIVSC 968
P EV+DV+ ++G+G++G V+KA +K T I A+KQV +E DL+E I EI I+ +C +VV Y +Y + LW+ +EYC G++ ++ +K L E I + L GL +LH IHRD+KAGN+L++ + KLADFGV+ +L KRNTV GTP+WMAPEVI E Y+C ADIWS GIT +E+A+ +PPY + P R + I PPT +P LWS F F+K+CL K PE R LL PF+ S
Sbjct: 26 PEEVFDVLEKLGEGSYGSVYKAIHKETGQIVAIKQVPVE--SDLQEIIKEISIMQQCDSPHVVKYYGSYFKNTDLWIVMEYCGAGSVSDIIRLRNKTLTEDEIATILQSTLKGLEYLHFMRKIHRDIKAGNILLNTEGHAKLADFGVAGQLTDTMAKRNTVIGTPFWMAPEVI----QEIGYNCVADIWSLGITAIEMAEGKPPYADIHPMRAIFMIPTNPPPTFRKPELWSDNFTDFVKQCLVKSPEQRATATQLLQHPFVRSA 284
BLAST of Serine/threonine-protein kinase 10 vs. Ensembl Human
Match: STK4 (serine/threonine kinase 4 [Source:HGNC Symbol;Acc:HGNC:11408]) HSP 1 Score: 246.899 bits (629), Expect = 2.146e-71 Identity = 118/265 (44.53%), Postives = 163/265 (61.51%), Query Frame = 3
Query: 174 PNEVWDVIGEIGDGAFGKVFKAKNKSTDDIAALKQVNLEEEGDLEEYIVEIEILTECKHANVVNLYNAYHFESKLWMALEYCNGGALDSLMITLDKNLNEKAIKYTSKEILSGLIFLHTNGVIHRDMKAGNVLVSKDADVKLADFGVSAKLAADKQKRNTVQGTPYWMAPEVIACQNMESYYDCRADIWSFGITLMELAQMRPPYHQMQPTRVLIKIAKADPPTLDRPSLWSSAFISFLKRCLTKKPEDRPHGPDLLSDPFIVSC 968
P EV+DV+ ++G+G++G V+KA +K T I A+KQV +E DL+E I EI I+ +C +VV Y +Y + LW+ +EYC G++ ++ +K L E I + L GL +LH IHRD+KAGN+L++ + KLADFGV+ +L KRNTV GTP+WMAPEVI E Y+C ADIWS GIT +E+A+ +PPY + P R + I PPT +P LWS F F+K+CL K PE R LL PF+ S
Sbjct: 26 PEEVFDVLEKLGEGSYGSVYKAIHKETGQIVAIKQVPVE--SDLQEIIKEISIMQQCDSPHVVKYYGSYFKNTDLWIVMEYCGAGSVSDIIRLRNKTLTEDEIATILQSTLKGLEYLHFMRKIHRDIKAGNILLNTEGHAKLADFGVAGQLTDTMAKRNTVIGTPFWMAPEVI----QEIGYNCVADIWSLGITAIEMAEGKPPYADIHPMRAIFMIPTNPPPTFRKPELWSDNFTDFVKQCLVKSPEQRATATQLLQHPFVRSA 284
BLAST of Serine/threonine-protein kinase 10 vs. Ensembl Celegans
Match: gck-4 (Germinal Center Kinase family [Source:UniProtKB/TrEMBL;Acc:O17566]) HSP 1 Score: 305.064 bits (780), Expect = 4.483e-87 Identity = 140/290 (48.28%), Postives = 204/290 (70.34%), Query Frame = 3
Query: 87 MAFIRDLFKRFKANDPKTK-KSYSYLNKCDPNEVWDVIGEIGDGAFGKVFKAKNKSTDDI-AALKQVNLEEEGDLEEYIVEIEILTECK-HANVVNLYNAYHFESKLWMALEYCNGGALDSLMITLDKNLNEKAIKYTSKEILSGLIFLHTNGVIHRDMKAGNVLVSKDADVKLADFGVSAKLAADKQKRNTVQGTPYWMAPEVIACQNM-ESYYDCRADIWSFGITLMELAQMRPPYHQMQPTRVLIKIAKADPPTLDRPSLWSSAFISFLKRCLTKKPEDRPHGPDLL 944
MAF+ + F+AN + K SY Y N +P + W++IGE+GDGAFGKV KA +++ + AA K + ++E +LE+++VEIEIL+ECK H ++ LY+ Y FE+KL M LE+C GGA+D++++ L L E I+Y + L +LH+ VIHRD+KAGN+L+++D V+LADFGVSAKL ++++KR+T GTPYWMAPEV+AC+ + YDC +DIWSFGITL+E+AQ PP+ + RV+IK+ K++PPTL +PS W+ +F L RCL K P +RP ++
Sbjct: 1 MAFLNKVKNLFRANQAEKKLPSYIYDN-VNPRDHWNIIGELGDGAFGKVEKAVSRTDPKLFAASKSIEIQEGEELEDFLVEIEILSECKGHPVMLGLYSTYFFENKLTMLLEFCGGGAVDNIIVELGHVLKEDQIRYIGYYVCDALKWLHSQNVIHRDLKAGNILLTQDGQVRLADFGVSAKLKSEREKRDTFIGTPYWMAPEVMACETFKDQPYDCISDIWSFGITLIEMAQGEPPHSDVSVMRVIIKVQKSEPPTLLQPSHWTRSFSDILTRCLVKDPRNRPPAAEIF 289 HSP 2 Score: 110.538 bits (275), Expect = 2.990e-24 Identity = 88/312 (28.21%), Postives = 171/312 (54.81%), Query Frame = 3
Query: 1482 NRKKSFYKTMTK-TRKFIVDGEEITTTTTKVVREGLENKNRDQIQDRKMEIRELQLLAKEESREKRQLQFKMLSERDNLASRQKSDELTFEKSHETEMDNLNKLHKSKLENLENQNYHELTNYQKRLLADKAKKENDFKNKEKTE---FGKELDRLPKHQKRENGKKLRDNNNIIFQEKFKAFQDQLMKDIEEKCESMTATHRLKICELELSLMKEKHQKLSKYNKEKANLEMDQCQSSYQLENQQKKEMFMLGKSQVKHRQEKEIEHLEKNNKKELDELDYIQQNEKKTFPRFIKNTSRTRNIQKKAELEI 2405
RK +T+TK TR +++DG ++T+TT V+ G+++ D++Q RK ++ +L+ L ++E+R+K++LQ + + + A + S++ ++ E EMD + + + ++E+ E HEL N QKRL ++ K FK + K E F +EL L K Q+++ K+ ++ I Q K K F QL ++ E + M H+ ++ +E + +KH L LE Q + + L + K+ + L ++Q+ R ++E+ +EK +++E D+L ++K P+ +++ ++TR++ K L I
Sbjct: 792 GRKDGNRQTITKKTRTYMIDGVQVTSTTVHVL--GVKD---DKVQ-RKQQLHDLRRLQRDEARQKQELQAEGIKLVEEQARKFTSEQTNLTRTSELEMDAMERRQRKEIEDTEGAQEHELRNAQKRLRIEQEKDMRAFKERLKQEMKIFKQELTMLSKVQRKDALKQRKEQIEIEHQLKEKDFLMQLQQNAEAMLQRMAEKHKERMASIEKQFLMQKHNLLRAKENNIWELEDKQMREKFVLHRKLFKDEYYLLRTQMLARHQREMAQIEKIHQEEEDDLIRALTLDRKKLPKMLRSETKTRSVMFKESLRI 1097
BLAST of Serine/threonine-protein kinase 10 vs. Ensembl Celegans
Match: cst-2 (Caenorhabditis STE20-like kinase [Source:UniProtKB/TrEMBL;Acc:Q304D8]) HSP 1 Score: 241.121 bits (614), Expect = 1.393e-70 Identity = 121/276 (43.84%), Postives = 169/276 (61.23%), Query Frame = 3
Query: 153 SYLNKCDPNEVWDVIGEIGDGAFGKVFKAKNKSTDDIAALKQVNLEEEGDLEEYIVEIEILTECKHANVVNLYNAYHFESKLWMALEYCNGGALDSLMITLDKNLNEKAIKYTSKEILSGLIFLHTNGVIHRDMKAGNVLVSKDADVKLADFGVSAKLAADKQKRNTVQGTPYWMAPEVIACQNMESYYDCRADIWSFGITLMELAQMRPPYHQMQPTRVLIKIAKADPPTLDRPSLWSSAFISFLKRCLTKKPEDRPHGPDLLSDPFIVSCNDSD 980
S LNK P EV+D++G++G+G++G V KA ++ + + A+K+V ++ DL+E I EI I+ +CK VV Y +Y S LW+ +EYC G++ +M K L+E+ I ++ L GL +LH IHRD+KAGN+L++ D KLADFGV+ +L KRNTV GTP+WMAPEVI E YD +ADIWS GIT +E+A+ RPPY + P R + I PPT +P WSS F F++ CL KKPE+R L FI + D
Sbjct: 25 SALNK-PPEEVFDIVGKLGEGSYGSVHKAIHRESGHVLAIKKVPVDT--DLQEIIKEISIMQQCKSKYVVKYYGSYFKHSDLWIVMEYCGAGSISDIMRARRKPLSEQEISAVLRDTLKGLQYLHDLKKIHRDIKAGNILLNTDGIAKLADFGVAGQLTDTMAKRNTVIGTPFWMAPEVIE----EIGYDTKADIWSLGITAIEMAEGRPPYSDIHPMRAIFMIPTKPPPTFKKPEEWSSEFNDFIRSCLIKKPEERKTALRLCEHTFIKNAPGCD 293
BLAST of Serine/threonine-protein kinase 10 vs. Ensembl Celegans
Match: cst-1 (Serine/threonine-protein kinase cst-1 Serine/threonine-protein kinase cst-1 37kDa subunit Serine/threonine-protein kinase cst-1 18kDa subunit [Source:UniProtKB/Swiss-Prot;Acc:Q9NB31]) HSP 1 Score: 242.276 bits (617), Expect = 3.934e-70 Identity = 121/276 (43.84%), Postives = 169/276 (61.23%), Query Frame = 3
Query: 153 SYLNKCDPNEVWDVIGEIGDGAFGKVFKAKNKSTDDIAALKQVNLEEEGDLEEYIVEIEILTECKHANVVNLYNAYHFESKLWMALEYCNGGALDSLMITLDKNLNEKAIKYTSKEILSGLIFLHTNGVIHRDMKAGNVLVSKDADVKLADFGVSAKLAADKQKRNTVQGTPYWMAPEVIACQNMESYYDCRADIWSFGITLMELAQMRPPYHQMQPTRVLIKIAKADPPTLDRPSLWSSAFISFLKRCLTKKPEDRPHGPDLLSDPFIVSCNDSD 980
S LNK P EV+D++G++G+G++G V KA ++ + + A+K+V ++ DL+E I EI I+ +CK VV Y +Y S LW+ +EYC G++ +M K L+E+ I ++ L GL +LH IHRD+KAGN+L++ D KLADFGV+ +L KRNTV GTP+WMAPEVI E YD +ADIWS GIT +E+A+ RPPY + P R + I PPT +P WSS F F++ CL KKPE+R L FI + D
Sbjct: 25 SALNK-PPEEVFDIVGKLGEGSYGSVHKAIHRESGHVLAIKKVPVDT--DLQEIIKEISIMQQCKSKYVVKYYGSYFKHSDLWIVMEYCGAGSISDIMRARRKPLSEQEISAVLRDTLKGLQYLHDLKKIHRDIKAGNILLNTDGIAKLADFGVAGQLTDTMAKRNTVIGTPFWMAPEVIE----EIGYDTKADIWSLGITAIEMAEGRPPYSDIHPMRAIFMIPTKPPPTFKKPEEWSSEFNDFIRSCLIKKPEERKTALRLCEHTFIKNAPGCD 293
BLAST of Serine/threonine-protein kinase 10 vs. Ensembl Celegans
Match: cst-1 (Serine/threonine-protein kinase cst-1 Serine/threonine-protein kinase cst-1 37kDa subunit Serine/threonine-protein kinase cst-1 18kDa subunit [Source:UniProtKB/Swiss-Prot;Acc:Q9NB31]) HSP 1 Score: 242.276 bits (617), Expect = 4.305e-70 Identity = 121/276 (43.84%), Postives = 169/276 (61.23%), Query Frame = 3
Query: 153 SYLNKCDPNEVWDVIGEIGDGAFGKVFKAKNKSTDDIAALKQVNLEEEGDLEEYIVEIEILTECKHANVVNLYNAYHFESKLWMALEYCNGGALDSLMITLDKNLNEKAIKYTSKEILSGLIFLHTNGVIHRDMKAGNVLVSKDADVKLADFGVSAKLAADKQKRNTVQGTPYWMAPEVIACQNMESYYDCRADIWSFGITLMELAQMRPPYHQMQPTRVLIKIAKADPPTLDRPSLWSSAFISFLKRCLTKKPEDRPHGPDLLSDPFIVSCNDSD 980
S LNK P EV+D++G++G+G++G V KA ++ + + A+K+V ++ DL+E I EI I+ +CK VV Y +Y S LW+ +EYC G++ +M K L+E+ I ++ L GL +LH IHRD+KAGN+L++ D KLADFGV+ +L KRNTV GTP+WMAPEVI E YD +ADIWS GIT +E+A+ RPPY + P R + I PPT +P WSS F F++ CL KKPE+R L FI + D
Sbjct: 25 SALNK-PPEEVFDIVGKLGEGSYGSVHKAIHRESGHVLAIKKVPVDT--DLQEIIKEISIMQQCKSKYVVKYYGSYFKHSDLWIVMEYCGAGSISDIMRARRKPLSEQEISAVLRDTLKGLQYLHDLKKIHRDIKAGNILLNTDGIAKLADFGVAGQLTDTMAKRNTVIGTPFWMAPEVIE----EIGYDTKADIWSLGITAIEMAEGRPPYSDIHPMRAIFMIPTKPPPTFKKPEEWSSEFNDFIRSCLIKKPEERKTALRLCEHTFIKNAPGCD 293
BLAST of Serine/threonine-protein kinase 10 vs. Ensembl Celegans
Match: gck-1 (Germinal center kinase 1 [Source:UniProtKB/Swiss-Prot;Acc:H2L099]) HSP 1 Score: 219.55 bits (558), Expect = 1.510e-60 Identity = 118/281 (41.99%), Postives = 169/281 (60.14%), Query Frame = 3
Query: 120 KANDPKTKKSYSYLNKCDPNEVWDVIGEIGDGAFGKVFKAKNKSTDDIAALKQVNLEE-EGDLEEYIVEIEILTECKHANVVNLYNAYHFESKLWMALEYCNGGALDSLMITLDKNLNEKAIKYTSKEILSGLIFLHTNGVIHRDMKAGNVLVSKDADVKLADFGVSAKLAADKQKRNTVQGTPYWMAPEVIACQNMESYYDCRADIWSFGITLMELAQMRPPYHQMQPTRVLIKIAKADPPTLDRPSLWSSAFISFLKRCLTKKPEDRPHGPDLLSDPFI 959
+A+D K Y+ K DP ++ IG G+FG+V+K + T + A+K ++LE+ E ++E+ EI++L++C V + ++ SKLW+ +EY GG+ +L +T L+E I +EIL GL +LH+ IHRD+KA NVLVS+ DVK+ADFGV+ +L +KR T G+P+WMAPE+I +S YD +ADIWS GIT +ELA PP+ + P RVL I K PP L + S WS F F++ CL K PE+RP LL FI
Sbjct: 12 QADDDSMKWDRIYIQKLDPEVIFTKQERIGRGSFGEVYKGIDNRTGRVVAIKIIDLEQAEDEIEDIQQEIQVLSQCDSQYVTKYFGSFLKGSKLWIIMEYLGGGS--ALDLTKSGKLDESHIAVILREILKGLEYLHSERKIHRDIKAANVLVSEHGDVKVADFGVAGQLTETVKKRITFVGSPFWMAPELIK----QSSYDYKADIWSLGITAIELANGEPPHSDLHPMRVLFLIPKNPPPVL-QGSQWSKPFKEFVEMCLNKDPENRPSASTLLKHQFI 285
BLAST of Serine/threonine-protein kinase 10 vs. Ensembl Fly
Match: Slik (gene:FBgn0035001 transcript:FBtr0072363) HSP 1 Score: 325.479 bits (833), Expect = 6.767e-94 Identity = 153/295 (51.86%), Postives = 200/295 (67.80%), Query Frame = 3
Query: 87 MAFIRDLFKRFKANDPKTKKSYSYLN---KCDPNEVWDVIGEIGDGAFGKVFKAKNKSTDDIAALKQVNLEEEGDLEEYIVEIEILTECKHANVVNLYNAYHFESKLWMALEYCNGGALDSLMITLDKNLNEKAIKYTSKEILSGLIFLHTNGVIHRDMKAGNVLVSKDADVKLADFGVSAKLAADKQKRNTVQGTPYWMAPEVIACQNM-ESYYDCRADIWSFGITLMELAQMRPPYHQMQPTRVLIKIAKADPPTLDRPSLWSSAFISFLKRCLTKKPEDRPHGPDLLSDPFI 959
M+FI +L K F + KK Y N DP E W+++GE+GDGAFGKV+KA++K AA K LE+E +L +++VEI+IL+E KH N+V LY A+ + KLWM +EYC+GGALDS+M+ L+K L E I Y K + GL FLH N VIHRD+KAGNVL++ + VKLADFGVSAK QK +T GTPYWMAPE++ C+ ++ YD + DIWS GITL+ELAQM PP +M P RVL+KI K++PP L++PS WS F FLK+ L K P+ RP L+ FI
Sbjct: 1 MSFITNLKKVFHLGGGEAKKKRLYNNIKMDTDPAEFWEMVGELGDGAFGKVYKAQHKEQKRFAAAKMCQLEDEENLSDHMVEIDILSEIKHPNIVELYEAFSIDDKLWMLIEYCDGGALDSIMVELEKPLTEPQIAYVCKHMTEGLTFLHRNKVIHRDLKAGNVLLTMEGGVKLADFGVSAKNKHTMQKHDTFIGTPYWMAPELVLCETFRDNPYDHKVDIWSLGITLIELAQMEPPNSEMSPMRVLLKIQKSEPPKLEQPSRWSKEFNDFLKKSLVKDPQVRPTTDVLMQHAFI 295 HSP 2 Score: 92.8189 bits (229), Expect = 9.155e-19 Identity = 77/297 (25.93%), Postives = 153/297 (51.52%), Query Frame = 3
Query: 1527 FIVDGEEITTTTTKVVREGLENKNRDQIQD-RKMEIRELQLLAKEESREKRQLQFKMLSERDNLASRQKSDELTFEKSHETEMDNLNKLHKSKLENLENQNYHELTNYQKRLLADKAKKENDFKNKEKTE---FGKELDRLPKHQKRENGKKLRDNNNIIFQEKFKAFQDQLMKDIEEKCESMTATHRLKICELELSLMKEKHQKLSKYNKEKANLEMDQCQSSYQLENQQKKEMFMLGKSQVKHRQEKEIEHLEKNNKKELDELDYIQQNEKKTFPRFIKNTSRTRNIQKKAELEI 2405
F +DG ++TTTT++V+ EN D RK E+REL+LL K+E +++ +L K ++ R + + + EK++E +MD L + HK +E E +EL + KR+ +++ ++ F+ K E +E+D PK ++++ K+ R + +EK +AF D L + E ++ HR + + + +++K + LE Q +QL + KE+ + + Q+ R EKE++ +++ +++ +++ Q EK+ P+ I+ + R++ + L I
Sbjct: 902 FEIDGVQMTTTTSRVIYGDDENGRIYDDHDFRKQELRELKLLQKQEKKQQTELHLKEQQAKEQQDRRFEQERSSLEKTYEADMDMLARQHKQLVEKTEQTQENELRSSSKRIRSEQEQELKIFRENLKQEIRLLKQEVDLFPKDKRKDEFKQRRSAMELDHEEKERAFLDSLKERHELLLRRLSEKHRDHLATINRNFLQQKQNAMRTREALLWELEEKQLHERHQLSKRHVKELCFMQRHQMIIRHEKELDQVKRMLQRKEEDMVKKQTMEKRALPKRIRAERKARDLMFRESLRI 1198
BLAST of Serine/threonine-protein kinase 10 vs. Ensembl Fly
Match: Slik (gene:FBgn0035001 transcript:FBtr0100470) HSP 1 Score: 325.479 bits (833), Expect = 9.900e-94 Identity = 153/295 (51.86%), Postives = 200/295 (67.80%), Query Frame = 3
Query: 87 MAFIRDLFKRFKANDPKTKKSYSYLN---KCDPNEVWDVIGEIGDGAFGKVFKAKNKSTDDIAALKQVNLEEEGDLEEYIVEIEILTECKHANVVNLYNAYHFESKLWMALEYCNGGALDSLMITLDKNLNEKAIKYTSKEILSGLIFLHTNGVIHRDMKAGNVLVSKDADVKLADFGVSAKLAADKQKRNTVQGTPYWMAPEVIACQNM-ESYYDCRADIWSFGITLMELAQMRPPYHQMQPTRVLIKIAKADPPTLDRPSLWSSAFISFLKRCLTKKPEDRPHGPDLLSDPFI 959
M+FI +L K F + KK Y N DP E W+++GE+GDGAFGKV+KA++K AA K LE+E +L +++VEI+IL+E KH N+V LY A+ + KLWM +EYC+GGALDS+M+ L+K L E I Y K + GL FLH N VIHRD+KAGNVL++ + VKLADFGVSAK QK +T GTPYWMAPE++ C+ ++ YD + DIWS GITL+ELAQM PP +M P RVL+KI K++PP L++PS WS F FLK+ L K P+ RP L+ FI
Sbjct: 1 MSFITNLKKVFHLGGGEAKKKRLYNNIKMDTDPAEFWEMVGELGDGAFGKVYKAQHKEQKRFAAAKMCQLEDEENLSDHMVEIDILSEIKHPNIVELYEAFSIDDKLWMLIEYCDGGALDSIMVELEKPLTEPQIAYVCKHMTEGLTFLHRNKVIHRDLKAGNVLLTMEGGVKLADFGVSAKNKHTMQKHDTFIGTPYWMAPELVLCETFRDNPYDHKVDIWSLGITLIELAQMEPPNSEMSPMRVLLKIQKSEPPKLEQPSRWSKEFNDFLKKSLVKDPQVRPTTDVLMQHAFI 295 HSP 2 Score: 92.8189 bits (229), Expect = 1.054e-18 Identity = 77/297 (25.93%), Postives = 153/297 (51.52%), Query Frame = 3
Query: 1527 FIVDGEEITTTTTKVVREGLENKNRDQIQD-RKMEIRELQLLAKEESREKRQLQFKMLSERDNLASRQKSDELTFEKSHETEMDNLNKLHKSKLENLENQNYHELTNYQKRLLADKAKKENDFKNKEKTE---FGKELDRLPKHQKRENGKKLRDNNNIIFQEKFKAFQDQLMKDIEEKCESMTATHRLKICELELSLMKEKHQKLSKYNKEKANLEMDQCQSSYQLENQQKKEMFMLGKSQVKHRQEKEIEHLEKNNKKELDELDYIQQNEKKTFPRFIKNTSRTRNIQKKAELEI 2405
F +DG ++TTTT++V+ EN D RK E+REL+LL K+E +++ +L K ++ R + + + EK++E +MD L + HK +E E +EL + KR+ +++ ++ F+ K E +E+D PK ++++ K+ R + +EK +AF D L + E ++ HR + + + +++K + LE Q +QL + KE+ + + Q+ R EKE++ +++ +++ +++ Q EK+ P+ I+ + R++ + L I
Sbjct: 902 FEIDGVQMTTTTSRVIYGDDENGRIYDDHDFRKQELRELKLLQKQEKKQQTELHLKEQQAKEQQDRRFEQERSSLEKTYEADMDMLARQHKQLVEKTEQTQENELRSSSKRIRSEQEQELKIFRENLKQEIRLLKQEVDLFPKDKRKDEFKQRRSAMELDHEEKERAFLDSLKERHELLLRRLSEKHRDHLATINRNFLQQKQNAMRTREALLWELEEKQLHERHQLSKRHVKELCFMQRHQMIIRHEKELDQVKRMLQRKEEDMVKKQTMEKRALPKRIRAERKARDLMFRESLRI 1198
BLAST of Serine/threonine-protein kinase 10 vs. Ensembl Fly
Match: Slik (gene:FBgn0035001 transcript:FBtr0332925) HSP 1 Score: 325.479 bits (833), Expect = 1.062e-93 Identity = 153/295 (51.86%), Postives = 200/295 (67.80%), Query Frame = 3
Query: 87 MAFIRDLFKRFKANDPKTKKSYSYLN---KCDPNEVWDVIGEIGDGAFGKVFKAKNKSTDDIAALKQVNLEEEGDLEEYIVEIEILTECKHANVVNLYNAYHFESKLWMALEYCNGGALDSLMITLDKNLNEKAIKYTSKEILSGLIFLHTNGVIHRDMKAGNVLVSKDADVKLADFGVSAKLAADKQKRNTVQGTPYWMAPEVIACQNM-ESYYDCRADIWSFGITLMELAQMRPPYHQMQPTRVLIKIAKADPPTLDRPSLWSSAFISFLKRCLTKKPEDRPHGPDLLSDPFI 959
M+FI +L K F + KK Y N DP E W+++GE+GDGAFGKV+KA++K AA K LE+E +L +++VEI+IL+E KH N+V LY A+ + KLWM +EYC+GGALDS+M+ L+K L E I Y K + GL FLH N VIHRD+KAGNVL++ + VKLADFGVSAK QK +T GTPYWMAPE++ C+ ++ YD + DIWS GITL+ELAQM PP +M P RVL+KI K++PP L++PS WS F FLK+ L K P+ RP L+ FI
Sbjct: 1 MSFITNLKKVFHLGGGEAKKKRLYNNIKMDTDPAEFWEMVGELGDGAFGKVYKAQHKEQKRFAAAKMCQLEDEENLSDHMVEIDILSEIKHPNIVELYEAFSIDDKLWMLIEYCDGGALDSIMVELEKPLTEPQIAYVCKHMTEGLTFLHRNKVIHRDLKAGNVLLTMEGGVKLADFGVSAKNKHTMQKHDTFIGTPYWMAPELVLCETFRDNPYDHKVDIWSLGITLIELAQMEPPNSEMSPMRVLLKIQKSEPPKLEQPSRWSKEFNDFLKKSLVKDPQVRPTTDVLMQHAFI 295 HSP 2 Score: 92.8189 bits (229), Expect = 9.833e-19 Identity = 77/297 (25.93%), Postives = 153/297 (51.52%), Query Frame = 3
Query: 1527 FIVDGEEITTTTTKVVREGLENKNRDQIQD-RKMEIRELQLLAKEESREKRQLQFKMLSERDNLASRQKSDELTFEKSHETEMDNLNKLHKSKLENLENQNYHELTNYQKRLLADKAKKENDFKNKEKTE---FGKELDRLPKHQKRENGKKLRDNNNIIFQEKFKAFQDQLMKDIEEKCESMTATHRLKICELELSLMKEKHQKLSKYNKEKANLEMDQCQSSYQLENQQKKEMFMLGKSQVKHRQEKEIEHLEKNNKKELDELDYIQQNEKKTFPRFIKNTSRTRNIQKKAELEI 2405
F +DG ++TTTT++V+ EN D RK E+REL+LL K+E +++ +L K ++ R + + + EK++E +MD L + HK +E E +EL + KR+ +++ ++ F+ K E +E+D PK ++++ K+ R + +EK +AF D L + E ++ HR + + + +++K + LE Q +QL + KE+ + + Q+ R EKE++ +++ +++ +++ Q EK+ P+ I+ + R++ + L I
Sbjct: 916 FEIDGVQMTTTTSRVIYGDDENGRIYDDHDFRKQELRELKLLQKQEKKQQTELHLKEQQAKEQQDRRFEQERSSLEKTYEADMDMLARQHKQLVEKTEQTQENELRSSSKRIRSEQEQELKIFRENLKQEIRLLKQEVDLFPKDKRKDEFKQRRSAMELDHEEKERAFLDSLKERHELLLRRLSEKHRDHLATINRNFLQQKQNAMRTREALLWELEEKQLHERHQLSKRHVKELCFMQRHQMIIRHEKELDQVKRMLQRKEEDMVKKQTMEKRALPKRIRAERKARDLMFRESLRI 1212
BLAST of Serine/threonine-protein kinase 10 vs. Ensembl Fly
Match: Slik (gene:FBgn0035001 transcript:FBtr0290019) HSP 1 Score: 325.479 bits (833), Expect = 5.152e-93 Identity = 153/295 (51.86%), Postives = 200/295 (67.80%), Query Frame = 3
Query: 87 MAFIRDLFKRFKANDPKTKKSYSYLN---KCDPNEVWDVIGEIGDGAFGKVFKAKNKSTDDIAALKQVNLEEEGDLEEYIVEIEILTECKHANVVNLYNAYHFESKLWMALEYCNGGALDSLMITLDKNLNEKAIKYTSKEILSGLIFLHTNGVIHRDMKAGNVLVSKDADVKLADFGVSAKLAADKQKRNTVQGTPYWMAPEVIACQNM-ESYYDCRADIWSFGITLMELAQMRPPYHQMQPTRVLIKIAKADPPTLDRPSLWSSAFISFLKRCLTKKPEDRPHGPDLLSDPFI 959
M+FI +L K F + KK Y N DP E W+++GE+GDGAFGKV+KA++K AA K LE+E +L +++VEI+IL+E KH N+V LY A+ + KLWM +EYC+GGALDS+M+ L+K L E I Y K + GL FLH N VIHRD+KAGNVL++ + VKLADFGVSAK QK +T GTPYWMAPE++ C+ ++ YD + DIWS GITL+ELAQM PP +M P RVL+KI K++PP L++PS WS F FLK+ L K P+ RP L+ FI
Sbjct: 1 MSFITNLKKVFHLGGGEAKKKRLYNNIKMDTDPAEFWEMVGELGDGAFGKVYKAQHKEQKRFAAAKMCQLEDEENLSDHMVEIDILSEIKHPNIVELYEAFSIDDKLWMLIEYCDGGALDSIMVELEKPLTEPQIAYVCKHMTEGLTFLHRNKVIHRDLKAGNVLLTMEGGVKLADFGVSAKNKHTMQKHDTFIGTPYWMAPELVLCETFRDNPYDHKVDIWSLGITLIELAQMEPPNSEMSPMRVLLKIQKSEPPKLEQPSRWSKEFNDFLKKSLVKDPQVRPTTDVLMQHAFI 295 HSP 2 Score: 93.2041 bits (230), Expect = 7.860e-19 Identity = 77/297 (25.93%), Postives = 153/297 (51.52%), Query Frame = 3
Query: 1527 FIVDGEEITTTTTKVVREGLENKNRDQIQD-RKMEIRELQLLAKEESREKRQLQFKMLSERDNLASRQKSDELTFEKSHETEMDNLNKLHKSKLENLENQNYHELTNYQKRLLADKAKKENDFKNKEKTE---FGKELDRLPKHQKRENGKKLRDNNNIIFQEKFKAFQDQLMKDIEEKCESMTATHRLKICELELSLMKEKHQKLSKYNKEKANLEMDQCQSSYQLENQQKKEMFMLGKSQVKHRQEKEIEHLEKNNKKELDELDYIQQNEKKTFPRFIKNTSRTRNIQKKAELEI 2405
F +DG ++TTTT++V+ EN D RK E+REL+LL K+E +++ +L K ++ R + + + EK++E +MD L + HK +E E +EL + KR+ +++ ++ F+ K E +E+D PK ++++ K+ R + +EK +AF D L + E ++ HR + + + +++K + LE Q +QL + KE+ + + Q+ R EKE++ +++ +++ +++ Q EK+ P+ I+ + R++ + L I
Sbjct: 902 FEIDGVQMTTTTSRVIYGDDENGRIYDDHDFRKQELRELKLLQKQEKKQQTELHLKEQQAKEQQDRRFEQERSSLEKTYEADMDMLARQHKQLVEKTEQTQENELRSSSKRIRSEQEQELKIFRENLKQEIRLLKQEVDLFPKDKRKDEFKQRRSAMELDHEEKERAFLDSLKERHELLLRRLSEKHRDHLATINRNFLQQKQNAMRTREALLWELEEKQLHERHQLSKRHVKELCFMQRHQMIIRHEKELDQVKRMLQRKEEDMVKKQTMEKRALPKRIRAERKARDLMFRESLRI 1198
BLAST of Serine/threonine-protein kinase 10 vs. Ensembl Fly
Match: Slik (gene:FBgn0035001 transcript:FBtr0072366) HSP 1 Score: 324.709 bits (831), Expect = 1.159e-92 Identity = 153/295 (51.86%), Postives = 200/295 (67.80%), Query Frame = 3
Query: 87 MAFIRDLFKRFKANDPKTKKSYSYLN---KCDPNEVWDVIGEIGDGAFGKVFKAKNKSTDDIAALKQVNLEEEGDLEEYIVEIEILTECKHANVVNLYNAYHFESKLWMALEYCNGGALDSLMITLDKNLNEKAIKYTSKEILSGLIFLHTNGVIHRDMKAGNVLVSKDADVKLADFGVSAKLAADKQKRNTVQGTPYWMAPEVIACQNM-ESYYDCRADIWSFGITLMELAQMRPPYHQMQPTRVLIKIAKADPPTLDRPSLWSSAFISFLKRCLTKKPEDRPHGPDLLSDPFI 959
M+FI +L K F + KK Y N DP E W+++GE+GDGAFGKV+KA++K AA K LE+E +L +++VEI+IL+E KH N+V LY A+ + KLWM +EYC+GGALDS+M+ L+K L E I Y K + GL FLH N VIHRD+KAGNVL++ + VKLADFGVSAK QK +T GTPYWMAPE++ C+ ++ YD + DIWS GITL+ELAQM PP +M P RVL+KI K++PP L++PS WS F FLK+ L K P+ RP L+ FI
Sbjct: 1 MSFITNLKKVFHLGGGEAKKKRLYNNIKMDTDPAEFWEMVGELGDGAFGKVYKAQHKEQKRFAAAKMCQLEDEENLSDHMVEIDILSEIKHPNIVELYEAFSIDDKLWMLIEYCDGGALDSIMVELEKPLTEPQIAYVCKHMTEGLTFLHRNKVIHRDLKAGNVLLTMEGGVKLADFGVSAKNKHTMQKHDTFIGTPYWMAPELVLCETFRDNPYDHKVDIWSLGITLIELAQMEPPNSEMSPMRVLLKIQKSEPPKLEQPSRWSKEFNDFLKKSLVKDPQVRPTTDVLMQHAFI 295 HSP 2 Score: 93.2041 bits (230), Expect = 7.893e-19 Identity = 77/297 (25.93%), Postives = 153/297 (51.52%), Query Frame = 3
Query: 1527 FIVDGEEITTTTTKVVREGLENKNRDQIQD-RKMEIRELQLLAKEESREKRQLQFKMLSERDNLASRQKSDELTFEKSHETEMDNLNKLHKSKLENLENQNYHELTNYQKRLLADKAKKENDFKNKEKTE---FGKELDRLPKHQKRENGKKLRDNNNIIFQEKFKAFQDQLMKDIEEKCESMTATHRLKICELELSLMKEKHQKLSKYNKEKANLEMDQCQSSYQLENQQKKEMFMLGKSQVKHRQEKEIEHLEKNNKKELDELDYIQQNEKKTFPRFIKNTSRTRNIQKKAELEI 2405
F +DG ++TTTT++V+ EN D RK E+REL+LL K+E +++ +L K ++ R + + + EK++E +MD L + HK +E E +EL + KR+ +++ ++ F+ K E +E+D PK ++++ K+ R + +EK +AF D L + E ++ HR + + + +++K + LE Q +QL + KE+ + + Q+ R EKE++ +++ +++ +++ Q EK+ P+ I+ + R++ + L I
Sbjct: 902 FEIDGVQMTTTTSRVIYGDDENGRIYDDHDFRKQELRELKLLQKQEKKQQTELHLKEQQAKEQQDRRFEQERSSLEKTYEADMDMLARQHKQLVEKTEQTQENELRSSSKRIRSEQEQELKIFRENLKQEIRLLKQEVDLFPKDKRKDEFKQRRSAMELDHEEKERAFLDSLKERHELLLRRLSEKHRDHLATINRNFLQQKQNAMRTREALLWELEEKQLHERHQLSKRHVKELCFMQRHQMIIRHEKELDQVKRMLQRKEEDMVKKQTMEKRALPKRIRAERKARDLMFRESLRI 1198
BLAST of Serine/threonine-protein kinase 10 vs. Ensembl Zebrafish
Match: slkb (STE20-like kinase b [Source:ZFIN;Acc:ZDB-GENE-030131-1684]) HSP 1 Score: 348.591 bits (893), Expect = 3.753e-104 Identity = 182/395 (46.08%), Postives = 266/395 (67.34%), Query Frame = 3
Query: 87 MAFIRDLFKRFKANDPKTKKSYSYLNK-CDPNEVWDVIGEIGDGAFGKVFKAKNKSTDDIAALKQVNLEEEGDLEEYIVEIEILTECKHANVVNLYNAYHFESKLWMALEYCNGGALDSLMITLDKNLNEKAIKYTSKEILSGLIFLHTNGVIHRDMKAGNVLVSKDADVKLADFGVSAKLAADKQKRNTVQGTPYWMAPEVIACQ-NMESYYDCRADIWSFGITLMELAQMRPPYHQMQPTRVLIKIAKADPPTLDRPSLWSSAFISFLKRCLTKKPEDRPHGPDLLSDPFIVSCNDSDKHALKVLXXXXXXXXXXXXXXDLDLKDMRHSLLPSQTFDDISEQDDASVGSSD---ILETPNVIDTIS---KSVFSAEILDNIISEQIKSEADKV 1247
M+F + K FK K KK Y ++++ +P E+W+++GE+GDGAFGKVFKA+NK T AA K ++ + E +LE+Y+VEI+IL C H N+V L +A++FESKLW+ +E+C GGA+D++M+ L++ L E I+ K+ L L++LH N VIHRD+KAGN+L++ D DVKLADFGVSAK Q+R++ GTPYWMAPEV+ C+ + + YD +ADIWS GITL+ELAQ+ PP H+M P RVL+KIAKA+PPTL +PS WS F FLK L K ++R LL PF+ + DS L+ LI EA AE EE+ E+ D ++ +LL + DASVGSS+ + ++P+ ++++ + V + ++ D+I++ +IK E D +
Sbjct: 1 MSFF-NFRKIFKLGIEKKKKQYDHVHRDTNPEEIWEIVGELGDGAFGKVFKAQNKQTGIFAAAKVIDTKTEDELEDYMVEIDILASCDHHNIVKLLDAFYFESKLWILIEFCAGGAVDAVMLELERPLTEPQIRVVCKQTLDALLYLHDNKVIHRDLKAGNILLTLDGDVKLADFGVSAKNTKTVQRRDSFIGTPYWMAPEVVMCETSKDRPYDYKADIWSLGITLIELAQIEPPNHEMNPMRVLLKIAKAEPPTLLQPSKWSPEFRDFLKHALEKNVDNRWSTAQLLQHPFVSTVTDS--RPLRELIAEAKAEVTEEMEEEEDDEEHEGNLLGHKRAP-----SDASVGSSEDEKLPQSPSTLESVPERIEEVSAPKLADDIVTAEIKKEEDPL 387 HSP 2 Score: 108.997 bits (271), Expect = 1.278e-23 Identity = 82/301 (27.24%), Postives = 153/301 (50.83%), Query Frame = 3
Query: 1503 KTMTKTRKFIVDGEEITTTTTKVVREGLENKNRDQIQDRKMEIRELQLLAKEESREKRQLQFKMLSERDNLASRQKSDELTFEKSHETEMDNLNKLHKSKLENLENQNYHELTNYQKRLLADKAKKENDFKNKEKTEFGKELDRLPKHQKRENGKKLRDNNNIIFQEKFKAFQDQLMKDIEEKCESMTATHRLKICELELSLMKEKHQKLSKYNKEKANLEMDQCQSSYQLENQQKKEMFMLGKSQVKHRQEKEIEHLEKNNKKELDELDYIQQNEKKTFPRFIKNTSRTRNIQKKAELEI 2405
KT+ KTRKF+VDG E++ TT+K++ + + KN + R+ E+REL+LL KEE R ++QL K+ +RD + R + + + ++ ++TE++N+ + K +E LE ++ L + KR+ A++ K+ + F+N K +E + + K Q+ D++ + + H+L++ E + K Q L LE Q +QL QQ K+ + + + Q+ R EKE+E + + N++ ++++ Q EK P+ ++ ++TR K L I
Sbjct: 554 KTLKKTRKFMVDGVEVSVTTSKIITDN-DTKNEEMRFLRRQELRELRLLQKEEQRAQQQLSNKLQQQRDQICRRFEHETTSKKRQYDTEVENMERQQKQTIERLEQEHTERLRDEAKRIKAEQDKELSKFQNTHKNRKKEEQEFVQKQQQ----------------------------DLDSALKKIIQQHKLELATTERDCLNHKQQLLRAREAAMWELEERHLQEKHQLYKQQLKDQYFMQRHQLLKRHEKEMEQMHRYNQRLMEDMKNRQMQEKTRLPKIQRSDAKTRMAMFKKSLRI 825
BLAST of Serine/threonine-protein kinase 10 vs. Ensembl Zebrafish
Match: slka (STE20-like kinase a [Source:ZFIN;Acc:ZDB-GENE-050411-66]) HSP 1 Score: 330.487 bits (846), Expect = 5.448e-96 Identity = 145/298 (48.66%), Postives = 210/298 (70.47%), Query Frame = 3
Query: 87 MAFIRDLFKRFKANDPKTKKSYSYLNK-CDPNEVWDVIGEIGDGAFGKVFKAKNKSTDDIAALKQVNLEEEGDLEEYIVEIEILTECKHANVVNLYNAYHFESKLWMALEYCNGGALDSLMITLDKNLNEKAIKYTSKEILSGLIFLHTNGVIHRDMKAGNVLVSKDADVKLADFGVSAKLAADKQKRNTVQGTPYWMAPEVIACQ-NMESYYDCRADIWSFGITLMELAQMRPPYHQMQPTRVLIKIAKADPPTLDRPSLWSSAFISFLKRCLTKKPEDRPHGPDLLSDPFIVSCND 974
M+F + K FK K KK Y ++N+ +P + W+++GE+GDGAFGKV+KA+NK T +AA K ++ + E +LE+Y+VEI+IL C H +V L +A+++ESKLW+ +E+C GGA+D++M+ L++ L E I+ K+ L L++LH N +IHRD+KAGN+L + D ++KLADFGVSAK Q+R++ GTPYWMAPEV+ C+ + + YD +ADIWS G+TL+ELAQ+ PP H+M P RVL+KIAK++PPTL PS WS F FL++ L K ++R LL PF+ S D
Sbjct: 1 MSFF-NFRKIFKLGTEKKKKQYEHVNRDVNPEDFWEIVGELGDGAFGKVYKAQNKQTGILAAAKVIDTKTEEELEDYMVEIDILASCDHQYIVKLLDAFYYESKLWILIEFCAGGAVDAVMLELERPLTEPQIRVVCKQSLEALVYLHENKIIHRDLKAGNILFTSDGNIKLADFGVSAKNTKTLQRRDSFIGTPYWMAPEVVMCETSKDRPYDYKADIWSLGVTLIELAQIEPPNHEMNPMRVLLKIAKSEPPTLASPSRWSPEFSDFLRKALDKNVDNRWSALQLLQHPFVSSLVD 297 HSP 2 Score: 97.0561 bits (240), Expect = 6.992e-20 Identity = 84/301 (27.91%), Postives = 154/301 (51.16%), Query Frame = 3
Query: 1503 KTMTKTRKFIVDGEEITTTTTKVVREGLENKNRDQIQDRKMEIRELQLLAKEESREKRQLQFKMLSERDNLASRQKSDELTFEKSHETEMDNLNKLHKSKLENLENQNYHELTNYQKRLLADKAKKENDFKNKEKTEFGKELDRLPKHQKRENGKKLRDNNNIIFQEKFKAFQDQLMKDIEEKCESMTATHRLKICELELSLMKEKHQKLSKYNKEKANLEMDQCQSSYQLENQQKKEMFMLGKSQVKHRQEKEIEHLEKNNKKELDELDYIQQNEKKTFPRFIKNTSRTRNIQKKAELEI 2405
KT+ KTRKF+VDG E++ TT+K+V + + K+ + R+ E+REL+LL KEE R ++QL K+ +++ L R + + ++ ++ E++NL K K +E LE + + L + KR+ A++ K+ + F+N K +E + L + Q+ +G L K I++ H+L+I +E + K Q + LE Q +QL QQ K+ + + + Q+ R +KE+E ++ N++ ++E+ Q E+ P+ ++ ++TR K L I
Sbjct: 787 KTLKKTRKFLVDGVEVSVTTSKIVTDN-DTKSEELRFLRRQELRELRLLQKEEQRAQQQLSNKLQQQKEQLFRRFEQEMSGKKRQYDQEVENLEKQQKQTIERLEQDHTNRLRDEAKRIKAEQDKELSKFQNMLKNRKKEEQEFLQRQQQELDGA--------------------LKKIIQQ--------HKLEIATIERDCLNHKQQLMRAREAAMWELEERHLQEKHQLLKQQLKDQYFMQRHQLLKRHDKEMEQMQGYNQRLIEEMKNRQAQERARLPKIQRSEAKTRMAMFKKSLRI 1058
BLAST of Serine/threonine-protein kinase 10 vs. Ensembl Zebrafish
Match: slka (STE20-like kinase a [Source:ZFIN;Acc:ZDB-GENE-050411-66]) HSP 1 Score: 330.487 bits (846), Expect = 8.070e-96 Identity = 145/298 (48.66%), Postives = 210/298 (70.47%), Query Frame = 3
Query: 87 MAFIRDLFKRFKANDPKTKKSYSYLNK-CDPNEVWDVIGEIGDGAFGKVFKAKNKSTDDIAALKQVNLEEEGDLEEYIVEIEILTECKHANVVNLYNAYHFESKLWMALEYCNGGALDSLMITLDKNLNEKAIKYTSKEILSGLIFLHTNGVIHRDMKAGNVLVSKDADVKLADFGVSAKLAADKQKRNTVQGTPYWMAPEVIACQ-NMESYYDCRADIWSFGITLMELAQMRPPYHQMQPTRVLIKIAKADPPTLDRPSLWSSAFISFLKRCLTKKPEDRPHGPDLLSDPFIVSCND 974
M+F + K FK K KK Y ++N+ +P + W+++GE+GDGAFGKV+KA+NK T +AA K ++ + E +LE+Y+VEI+IL C H +V L +A+++ESKLW+ +E+C GGA+D++M+ L++ L E I+ K+ L L++LH N +IHRD+KAGN+L + D ++KLADFGVSAK Q+R++ GTPYWMAPEV+ C+ + + YD +ADIWS G+TL+ELAQ+ PP H+M P RVL+KIAK++PPTL PS WS F FL++ L K ++R LL PF+ S D
Sbjct: 1 MSFF-NFRKIFKLGTEKKKKQYEHVNRDVNPEDFWEIVGELGDGAFGKVYKAQNKQTGILAAAKVIDTKTEEELEDYMVEIDILASCDHQYIVKLLDAFYYESKLWILIEFCAGGAVDAVMLELERPLTEPQIRVVCKQSLEALVYLHENKIIHRDLKAGNILFTSDGNIKLADFGVSAKNTKTLQRRDSFIGTPYWMAPEVVMCETSKDRPYDYKADIWSLGVTLIELAQIEPPNHEMNPMRVLLKIAKSEPPTLASPSRWSPEFSDFLRKALDKNVDNRWSALQLLQHPFVSSLVD 297 HSP 2 Score: 115.546 bits (288), Expect = 1.550e-25 Identity = 87/304 (28.62%), Postives = 167/304 (54.93%), Query Frame = 3
Query: 1503 KTMTKTRKFIVDGEEITTTTTKVVREGLENKNRDQIQDRKMEIRELQLLAKEESREKRQLQFKMLSERDNLASRQKSDELTFEKSHETEMDNLNKLHKSKLENLENQNYHELTNYQKRLLADKAKKENDFKN---KEKTEFGKELDRLPKHQKRENGKKLRDNNNIIFQEKFKAFQDQLMKDIEEKCESMTATHRLKICELELSLMKEKHQKLSKYNKEKANLEMDQCQSSYQLENQQKKEMFMLGKSQVKHRQEKEIEHLEKNNKKELDELDYIQQNEKKTFPRFIKNTSRTRNIQKKAELEI 2405
KT+ KTRKF+VDG E++ TT+K+V + + K+ + R+ E+REL+LL KEE R ++QL K+ +++ L R + + ++ ++ E++NL K K +E LE + + L + KR+ A++ K+ + F+N K E +E+ PKH ++E K+L+++ I + + F + ++++ + + H+L+I +E + K Q + LE Q +QL QQ K+ + + + Q+ R +KE+E ++ N++ ++E+ Q E+ P+ ++ ++TR K L I
Sbjct: 787 KTLKKTRKFLVDGVEVSVTTSKIVTDN-DTKSEELRFLRRQELRELRLLQKEEQRAQQQLSNKLQQQKEQLFRRFEQEMSGKKRQYDQEVENLEKQQKQTIERLEQDHTNRLRDEAKRIKAEQDKELSKFQNMLKNRKKEVKQEVGLSPKHMRKELMKRLKEDLAAIQHGEEQEFLQRQQQELDGALKKIIQQHKLEIATIERDCLNHKQQLMRAREAAMWELEERHLQEKHQLLKQQLKDQYFMQRHQLLKRHDKEMEQMQGYNQRLIEEMKNRQAQERARLPKIQRSEAKTRMAMFKKSLRI 1089
BLAST of Serine/threonine-protein kinase 10 vs. Ensembl Zebrafish
Match: si:dkey-81j8.6 (si:dkey-81j8.6 [Source:ZFIN;Acc:ZDB-GENE-091116-12]) HSP 1 Score: 313.538 bits (802), Expect = 1.032e-93 Identity = 144/306 (47.06%), Postives = 198/306 (64.71%), Query Frame = 3
Query: 87 MAFIRDLFKRFKANDPKTKKSYSYLNKCDPNEVWDVIGEIGDGAFGKVFKAKNKSTDDIAALKQVNLEEEGDLEEYIVEIEILTECKHANVVNLYNAYHFESKLWMALEYCNGGALDSLMITLDKNLNEKAIKYTSKEILSGLIFLHTNGVIHRDMKAGNVLVSKDADVKLADFGVSAKLAADKQKRNTVQGTPYWMAPEVIACQ-NMESYYDCRADIWSFGITLMELAQMRPPYHQMQPTRVLIKIAKADPPTLDRPSLWSSAFISFLKRCLTKKPEDRPHGPDLLSDPFIVSCNDSDKHALKVL 1001
MA + F R + + + DP++ W+ +GE+GDGAFGKV+KA+N++T + A+K + + E L++YI EI+IL C+H N+++L +A FE LW+ LEYC GGALD +M+ L++ L E+ I + L L +LH + +IHRD+KAGN+L++ D VKLADFGVSAK QKR+T GTPYWMAPEVI C+ + ++ Y +ADIWS GITL+E A+M PP+H + P RVL+KI K+ PPTL P WSS F FL+R L K PE R L++ PF S D ALK L
Sbjct: 1 MASLLMRFFRLGVEKKRVRHYENLKRDVDPHQSWETLGELGDGAFGKVYKAQNQTTGVLGAVKVIEVRSEEQLDDYITEIDILAACRHPNILSLLDAIFFEGWLWILLEYCPGGALDDIMLELERGLTEQQISEVCWQTLQALFYLHQHHIIHRDLKAGNILLTMDGQVKLADFGVSAKNDYTLQKRSTFIGTPYWMAPEVIMCETSKDNPYTSKADIWSMGITLIEAAEMEPPHHSLNPMRVLLKITKSPPPTLSNPRQWSSHFQDFLRRSLQKNPEARWGTQQLMAHPF--SYAGRDGRALKEL 304 HSP 2 Score: 83.5741 bits (205), Expect = 6.748e-16 Identity = 87/304 (28.62%), Postives = 154/304 (50.66%), Query Frame = 3
Query: 1506 TMTKTRKFIVDGEEITTTTTKVVREGLENKNRDQIQDRKMEIRELQLLAKEESREKRQLQFKMLSERDNLASRQKSDELTFEKS-HETEMDNLNKLHKSKLENLENQNYHELTNYQKRLLADKAKKENDFKNKEKTEFGKELDRLPKHQKRENGKKLRDNNNIIFQEKFKAFQDQLMKDIEEKCESMTATHRLKICELELSLMKEKHQKLSKYNKEKANLEMDQ--CQSSYQLENQQKKEMFMLGKSQVKHRQEKEIEHLEKNNKKELDELDYIQQNEKKTFPRFIKNTSRTRNIQKKAELEIQ 2408
T+ KTRKF+VDG E++ TT+KVV EG ++K + +R+ E+ L+LL +EE RE QL+ K+ +R+ + R E+T +K +++E++ L K ++ + +E ++ +L +R+ KA++E + K L PK ++R Q++ + + L K ++E H+ K+ +E + K Q+L K +E E++Q Q Y L QQ KE + L + Q+ R K+ E + + L+E +Q E+ +F + K +++R Q K EL Q
Sbjct: 327 TVKKTRKFMVDGREVSVTTSKVVSEG-DSKEKLMRYNRRQELHALKLLQREEQREHAQLELKLQQQREQMF-RHIEQEMTSKKQYYDSELERLEKQYQQQSGQMEAEHTSKLREDARRI---KAQQEKELSRKSSA-----LKADPKEEQR------------FLQKQQQELNEALQKGVQE--------HKRKVASMEWEITV-KSQQL-KRAREAVIWELEQRHLQEKYHLFKQQVKEQYSLQRQQLTKRHNKDKERASRFQQSLLEEQKSLQAQERASFLKTQKAEAKSRLNQLKMELRKQ 598
BLAST of Serine/threonine-protein kinase 10 vs. Ensembl Zebrafish
Match: stk3 (serine/threonine kinase 3 (STE20 homolog, yeast) [Source:NCBI gene;Acc:324125]) HSP 1 Score: 244.588 bits (623), Expect = 8.674e-71 Identity = 118/265 (44.53%), Postives = 161/265 (60.75%), Query Frame = 3
Query: 174 PNEVWDVIGEIGDGAFGKVFKAKNKSTDDIAALKQVNLEEEGDLEEYIVEIEILTECKHANVVNLYNAYHFESKLWMALEYCNGGALDSLMITLDKNLNEKAIKYTSKEILSGLIFLHTNGVIHRDMKAGNVLVSKDADVKLADFGVSAKLAADKQKRNTVQGTPYWMAPEVIACQNMESYYDCRADIWSFGITLMELAQMRPPYHQMQPTRVLIKIAKADPPTLDRPSLWSSAFISFLKRCLTKKPEDRPHGPDLLSDPFIVSC 968
P EV+DV+ ++G+G++G VFKA +K + + A+KQV +E DL+E I EI I+ +C VV Y +Y + LW+ +EYC G++ ++ +K L E I K L GL +LH IHRD+KAGN+L++ + KLADFGV+ +L KRNTV GTP+WMAPEVI E Y+C ADIWS GIT +E+A+ +PPY + P R + I PPT +P WS F F+K+CL K PE R LL PFIV
Sbjct: 22 PEEVFDVLEKLGEGSYGSVFKAIHKESGQVVAIKQVPVE--SDLQEIIKEISIMQQCDSPYVVKYYGSYFKNTDLWIVMEYCGAGSVSDIIRLRNKTLTEDEIATVLKSTLKGLEYLHFMRKIHRDIKAGNILLNTEGHAKLADFGVAGQLTDTMAKRNTVIGTPFWMAPEVI----QEIGYNCVADIWSLGITSIEMAEGKPPYADIHPMRAIFMIPTNPPPTFRKPEHWSDDFTDFVKKCLVKNPEQRATATQLLQHPFIVGA 280
BLAST of Serine/threonine-protein kinase 10 vs. Ensembl Xenopus
Match: stk10 (serine/threonine kinase 10 [Source:NCBI gene;Acc:780079]) HSP 1 Score: 338.961 bits (868), Expect = 4.932e-102 Identity = 148/280 (52.86%), Postives = 205/280 (73.21%), Query Frame = 3
Query: 144 KSYSYLNK-CDPNEVWDVIGEIGDGAFGKVFKAKNKSTDDIAALKQVNLEEEGDLEEYIVEIEILTECKHANVVNLYNAYHFESKLWMALEYCNGGALDSLMITLDKNLNEKAIKYTSKEILSGLIFLHTNGVIHRDMKAGNVLVSKDADVKLADFGVSAKLAADKQKRNTVQGTPYWMAPEVIACQNM-ESYYDCRADIWSFGITLMELAQMRPPYHQMQPTRVLIKIAKADPPTLDRPSLWSSAFISFLKRCLTKKPEDRPHGPDLLSDPFI--VSCN 971
+ Y ++ + DPN+VW++IGE+GDGAFGKV+KAKNK T +AA K + + E +LE+Y+VEIEIL C H +V L +Y++E KLW+ +E+C GGA+D++M+ LD+ L E I+ +++L GL +LH+ +IHRD+KAGNVL++ D D+KLADFGVSAK Q+R++ GTPYWMAPEV+ C+ M ++ YD +ADIWS GITL+E+AQ+ PP+H++ P RVL+KIAK++PPTL PS WS F +FLK L K PE RP LL PF+ VS N
Sbjct: 21 REYEHVRRDLDPNQVWEIIGELGDGAFGKVYKAKNKETGILAAAKVIETKNEEELEDYMVEIEILATCNHHFIVKLLGSYYWEGKLWIMIEFCPGGAVDAIMLELDRGLKEPEIRTICRQMLEGLTYLHSMKMIHRDLKAGNVLLTLDGDIKLADFGVSAKNVKTLQRRDSFIGTPYWMAPEVVMCETMKDAPYDYKADIWSLGITLIEMAQIEPPHHELNPMRVLLKIAKSEPPTLSSPSKWSPEFHNFLKTALDKNPETRPSAAQLLEHPFVKKVSGN 300 HSP 2 Score: 77.411 bits (189), Expect = 8.601e-14 Identity = 80/305 (26.23%), Postives = 151/305 (49.51%), Query Frame = 3
Query: 1506 TMTKTRKFIVDGEEITTTTTKVVREGLENKNRDQIQDRKMEIRELQLLAKEESREKRQLQFKMLSERDNLASRQKSDELTFEKSHETEMDNLNKLHKSKLENLENQNYHELTNYQKRLLADKAKKENDFKNKE-----KTEFGKELDRLPKHQKRENGKKLRDNNNIIFQEKFKAFQDQLMKDIEEKCESMTATHRLKICELELSLMKEKHQKLSKYNKEKANLEMDQCQSSYQLENQQKKEMFMLGKSQVKHRQEKEIEHLEKNNKKELDELDYIQQNEKKTFPRFIKNTSRTRNIQKKAELEI 2405
T+ +TR+F+VDG E++ TT+K++ + E K+ + R+ E+REL+LL KEE R + QL K + + + R + + + K +++E++ L + K ++E +E + H L + ++ + K E K E ++++LP+ Q+R+ K D+ F +K K IE S T T + ++++S +E+H Q +QL QQ K+ + L + ++ + EKE E +++ N++ +++L QQ E+ P+ K ++TR K L I
Sbjct: 387 TLKRTRRFVVDGVEVSITTSKIIGDD-EKKDEEMRFLRRQELRELRLLQKEEHRNQAQLTSKHSFQMEQMLRRFEQEMNSKRKFYDSELEALERHQKQQIERMEQE--HALRRRDEARRIRTEQERDHVKFLEQLKLRKKELKAQVEKLPRQQRRDAMKVQMDD----FAQK---------KHIEVGKLSFTYT----VFKVDIS--QERH-----------------LQERHQLVKQQLKDQYFLQRHELLRKHEKEQEQMQRYNQRMMEQLKLRQQQERARLPKNQKAEAKTRMTMFKKSLHI 652
BLAST of Serine/threonine-protein kinase 10 vs. Ensembl Xenopus
Match: stk10 (serine/threonine kinase 10 [Source:NCBI gene;Acc:780079]) HSP 1 Score: 341.658 bits (875), Expect = 1.680e-101 Identity = 148/280 (52.86%), Postives = 205/280 (73.21%), Query Frame = 3
Query: 144 KSYSYLNK-CDPNEVWDVIGEIGDGAFGKVFKAKNKSTDDIAALKQVNLEEEGDLEEYIVEIEILTECKHANVVNLYNAYHFESKLWMALEYCNGGALDSLMITLDKNLNEKAIKYTSKEILSGLIFLHTNGVIHRDMKAGNVLVSKDADVKLADFGVSAKLAADKQKRNTVQGTPYWMAPEVIACQNM-ESYYDCRADIWSFGITLMELAQMRPPYHQMQPTRVLIKIAKADPPTLDRPSLWSSAFISFLKRCLTKKPEDRPHGPDLLSDPFI--VSCN 971
+ Y ++ + DPN+VW++IGE+GDGAFGKV+KAKNK T +AA K + + E +LE+Y+VEIEIL C H +V L +Y++E KLW+ +E+C GGA+D++M+ LD+ L E I+ +++L GL +LH+ +IHRD+KAGNVL++ D D+KLADFGVSAK Q+R++ GTPYWMAPEV+ C+ M ++ YD +ADIWS GITL+E+AQ+ PP+H++ P RVL+KIAK++PPTL PS WS F +FLK L K PE RP LL PF+ VS N
Sbjct: 21 REYEHVRRDLDPNQVWEIIGELGDGAFGKVYKAKNKETGILAAAKVIETKNEEELEDYMVEIEILATCNHHFIVKLLGSYYWEGKLWIMIEFCPGGAVDAIMLELDRGLKEPEIRTICRQMLEGLTYLHSMKMIHRDLKAGNVLLTLDGDIKLADFGVSAKNVKTLQRRDSFIGTPYWMAPEVVMCETMKDAPYDYKADIWSLGITLIEMAQIEPPHHELNPMRVLLKIAKSEPPTLSSPSKWSPEFHNFLKTALDKNPETRPSAAQLLEHPFVKKVSGN 300 HSP 2 Score: 85.5001 bits (210), Expect = 3.326e-16 Identity = 82/310 (26.45%), Postives = 156/310 (50.32%), Query Frame = 3
Query: 1503 KTMTKTRKFIVDGEEITTTTTKVVREGLENKNRDQIQDRKMEIRELQLLAKEESREKRQLQFKMLSERDNLASRQKSDELTFEKSHETEMDNLNKLHKSKLENLENQNYHELTNYQKRLLADKAKKENDFKNKE-----KTEFGKELDRLPKHQKRENGKKLRDNNNIIFQEKFKAFQDQLM----KDIEEKCESMTATHRLKICELELSLMKEKHQKLSKYNKEKANLEMDQCQSSYQLENQQKKEMFMLGKSQVKHRQEKEIEHLEKNNKKELDELDYIQQNEKKTFPRFIKNTSRTRNIQKKAELEI 2405
KT+ +TR+F+VDG E++ TT+K++ + E K+ + R+ E+REL+LL KEE R + QL K + + + R + + + K +++E++ L + K ++E +E + H L + ++ + K E K E ++++LP+ Q+R+ K D+ F +K + Q + +D+ + +R +I E + +K Q L +LE Q +QL QQ K+ + L + ++ + EKE E +++ N++ +++L QQ E+ P+ K ++TR K L I
Sbjct: 509 KTLKRTRRFVVDGVEVSITTSKIIGDD-EKKDEEMRFLRRQELRELRLLQKEEHRNQAQLTSKHSFQMEQMLRRFEQEMNSKRKFYDSELEALERHQKQQIERMEQE--HALRRRDEARRIRTEQERDHVKFLEQLKLRKKELKAQVEKLPRQQRRDAMKVQMDD----FAQKKHIEEQQFLNKQKEDLTLALRVIVLENRKEIYNKEREFLNKKQQLLRDREAVIWDLEERHLQERHQLVKQQLKDQYFLQRHELLRKHEKEQEQMQRYNQRMMEQLKLRQQQERARLPKNQKAEAKTRMTMFKKSLHI 811
BLAST of Serine/threonine-protein kinase 10 vs. Ensembl Xenopus
Match: stk10 (serine/threonine kinase 10 [Source:NCBI gene;Acc:780079]) HSP 1 Score: 340.117 bits (871), Expect = 3.139e-101 Identity = 148/280 (52.86%), Postives = 205/280 (73.21%), Query Frame = 3
Query: 144 KSYSYLNK-CDPNEVWDVIGEIGDGAFGKVFKAKNKSTDDIAALKQVNLEEEGDLEEYIVEIEILTECKHANVVNLYNAYHFESKLWMALEYCNGGALDSLMITLDKNLNEKAIKYTSKEILSGLIFLHTNGVIHRDMKAGNVLVSKDADVKLADFGVSAKLAADKQKRNTVQGTPYWMAPEVIACQNM-ESYYDCRADIWSFGITLMELAQMRPPYHQMQPTRVLIKIAKADPPTLDRPSLWSSAFISFLKRCLTKKPEDRPHGPDLLSDPFI--VSCN 971
+ Y ++ + DPN+VW++IGE+GDGAFGKV+KAKNK T +AA K + + E +LE+Y+VEIEIL C H +V L +Y++E KLW+ +E+C GGA+D++M+ LD+ L E I+ +++L GL +LH+ +IHRD+KAGNVL++ D D+KLADFGVSAK Q+R++ GTPYWMAPEV+ C+ M ++ YD +ADIWS GITL+E+AQ+ PP+H++ P RVL+KIAK++PPTL PS WS F +FLK L K PE RP LL PF+ VS N
Sbjct: 21 REYEHVRRDLDPNQVWEIIGELGDGAFGKVYKAKNKETGILAAAKVIETKNEEELEDYMVEIEILATCNHHFIVKLLGSYYWEGKLWIMIEFCPGGAVDAIMLELDRGLKEPEIRTICRQMLEGLTYLHSMKMIHRDLKAGNVLLTLDGDIKLADFGVSAKNVKTLQRRDSFIGTPYWMAPEVVMCETMKDAPYDYKADIWSLGITLIEMAQIEPPHHELNPMRVLLKIAKSEPPTLSSPSKWSPEFHNFLKTALDKNPETRPSAAQLLEHPFVKKVSGN 300 HSP 2 Score: 86.6557 bits (213), Expect = 1.427e-16 Identity = 82/310 (26.45%), Postives = 156/310 (50.32%), Query Frame = 3
Query: 1503 KTMTKTRKFIVDGEEITTTTTKVVREGLENKNRDQIQDRKMEIRELQLLAKEESREKRQLQFKMLSERDNLASRQKSDELTFEKSHETEMDNLNKLHKSKLENLENQNYHELTNYQKRLLADKAKKENDFKNKE-----KTEFGKELDRLPKHQKRENGKKLRDNNNIIFQEKFKAFQDQLM----KDIEEKCESMTATHRLKICELELSLMKEKHQKLSKYNKEKANLEMDQCQSSYQLENQQKKEMFMLGKSQVKHRQEKEIEHLEKNNKKELDELDYIQQNEKKTFPRFIKNTSRTRNIQKKAELEI 2405
KT+ +TR+F+VDG E++ TT+K++ + E K+ + R+ E+REL+LL KEE R + QL K + + + R + + + K +++E++ L + K ++E +E + H L + ++ + K E K E ++++LP+ Q+R+ K D+ F +K + Q + +D+ + +R +I E + +K Q L +LE Q +QL QQ K+ + L + ++ + EKE E +++ N++ +++L QQ E+ P+ K ++TR K L I
Sbjct: 482 KTLKRTRRFVVDGVEVSITTSKIIGDD-EKKDEEMRFLRRQELRELRLLQKEEHRNQAQLTSKHSFQMEQMLRRFEQEMNSKRKFYDSELEALERHQKQQIERMEQE--HALRRRDEARRIRTEQERDHVKFLEQLKLRKKELKAQVEKLPRQQRRDAMKVQMDD----FAQKKHIEEQQFLNKQKEDLTLALRVIVLENRKEIYNKEREFLNKKQQLLRDREAVIWDLEERHLQERHQLVKQQLKDQYFLQRHELLRKHEKEQEQMQRYNQRMMEQLKLRQQQERARLPKNQKAEAKTRMTMFKKSLHI 784
BLAST of Serine/threonine-protein kinase 10 vs. Ensembl Xenopus
Match: stk10 (serine/threonine kinase 10 [Source:NCBI gene;Acc:780079]) HSP 1 Score: 340.502 bits (872), Expect = 3.356e-101 Identity = 148/280 (52.86%), Postives = 205/280 (73.21%), Query Frame = 3
Query: 144 KSYSYLNK-CDPNEVWDVIGEIGDGAFGKVFKAKNKSTDDIAALKQVNLEEEGDLEEYIVEIEILTECKHANVVNLYNAYHFESKLWMALEYCNGGALDSLMITLDKNLNEKAIKYTSKEILSGLIFLHTNGVIHRDMKAGNVLVSKDADVKLADFGVSAKLAADKQKRNTVQGTPYWMAPEVIACQNM-ESYYDCRADIWSFGITLMELAQMRPPYHQMQPTRVLIKIAKADPPTLDRPSLWSSAFISFLKRCLTKKPEDRPHGPDLLSDPFI--VSCN 971
+ Y ++ + DPN+VW++IGE+GDGAFGKV+KAKNK T +AA K + + E +LE+Y+VEIEIL C H +V L +Y++E KLW+ +E+C GGA+D++M+ LD+ L E I+ +++L GL +LH+ +IHRD+KAGNVL++ D D+KLADFGVSAK Q+R++ GTPYWMAPEV+ C+ M ++ YD +ADIWS GITL+E+AQ+ PP+H++ P RVL+KIAK++PPTL PS WS F +FLK L K PE RP LL PF+ VS N
Sbjct: 21 REYEHVRRDLDPNQVWEIIGELGDGAFGKVYKAKNKETGILAAAKVIETKNEEELEDYMVEIEILATCNHHFIVKLLGSYYWEGKLWIMIEFCPGGAVDAIMLELDRGLKEPEIRTICRQMLEGLTYLHSMKMIHRDLKAGNVLLTLDGDIKLADFGVSAKNVKTLQRRDSFIGTPYWMAPEVVMCETMKDAPYDYKADIWSLGITLIEMAQIEPPHHELNPMRVLLKIAKSEPPTLSSPSKWSPEFHNFLKTALDKNPETRPSAAQLLEHPFVKKVSGN 300 HSP 2 Score: 85.8853 bits (211), Expect = 2.084e-16 Identity = 82/310 (26.45%), Postives = 156/310 (50.32%), Query Frame = 3
Query: 1503 KTMTKTRKFIVDGEEITTTTTKVVREGLENKNRDQIQDRKMEIRELQLLAKEESREKRQLQFKMLSERDNLASRQKSDELTFEKSHETEMDNLNKLHKSKLENLENQNYHELTNYQKRLLADKAKKENDFKNKE-----KTEFGKELDRLPKHQKRENGKKLRDNNNIIFQEKFKAFQDQLM----KDIEEKCESMTATHRLKICELELSLMKEKHQKLSKYNKEKANLEMDQCQSSYQLENQQKKEMFMLGKSQVKHRQEKEIEHLEKNNKKELDELDYIQQNEKKTFPRFIKNTSRTRNIQKKAELEI 2405
KT+ +TR+F+VDG E++ TT+K++ + E K+ + R+ E+REL+LL KEE R + QL K + + + R + + + K +++E++ L + K ++E +E + H L + ++ + K E K E ++++LP+ Q+R+ K D+ F +K + Q + +D+ + +R +I E + +K Q L +LE Q +QL QQ K+ + L + ++ + EKE E +++ N++ +++L QQ E+ P+ K ++TR K L I
Sbjct: 499 KTLKRTRRFVVDGVEVSITTSKIIGDD-EKKDEEMRFLRRQELRELRLLQKEEHRNQAQLTSKHSFQMEQMLRRFEQEMNSKRKFYDSELEALERHQKQQIERMEQE--HALRRRDEARRIRTEQERDHVKFLEQLKLRKKELKAQVEKLPRQQRRDAMKVQMDD----FAQKKHIEEQQFLNKQKEDLTLALRVIVLENRKEIYNKEREFLNKKQQLLRDREAVIWDLEERHLQERHQLVKQQLKDQYFLQRHELLRKHEKEQEQMQRYNQRMMEQLKLRQQQERARLPKNQKAEAKTRMTMFKKSLHI 801
BLAST of Serine/threonine-protein kinase 10 vs. Ensembl Xenopus
Match: SLK (STE20 like kinase [Source:NCBI gene;Acc:100145483]) HSP 1 Score: 292.738 bits (748), Expect = 1.213e-84 Identity = 241/823 (29.28%), Postives = 395/823 (48.00%), Query Frame = 3
Query: 87 MAFIRDLFKRFKANDPKTKKSYSYLNK-CDPNEVWDVIGEIGDGAFGKVFKAKNKSTDDIAALKQVNLEEEGDLEEYIVEIEILTECKHANVVNLYNAYHFESKLWMALEYCNGGALDSLMITLDKNLNEKAIKYTSKEILSGLIFLHTNGVIHRDMKAGNVLVSKDADVKLADFGVSAKLAADKQKRNTVQGTPYWMAPEVIACQ-NMESYYDCRADIWSFGITLMELAQMRPPYHQMQPTRVLIKIAKADPPTLDRPSLWSSAFISFLKRCLTKKPEDRPHGPDLLSDPFIVSCNDSDKHALKVLXXXXXX--------------XXXXXXXXDLDLKDMRHSLLPSQTFDDI--SEQDDASVGSSDILET-----PNVIDTISKSVFSAEIL--------DNIISEQIKSEADKVSILGVVVDIMENNPCTNIDDTIAQLDEQNKFDRRRSIRMA---------------MDIVPDIPISDIKDNESVEKFSIKDEDSDKESNAQAILNRKKSFYKTMTKTRKFIVDGEEITTTTTKVVREGLENKNRDQIQDRKMEIRELQLLAKEESREKRQLQFKMLSERDNLASRQKSDELTFEKSHETEMDNLNKLHKSKLENLENQNYHELTNYQKRLLADKAKKENDFKNKEKTEFGKELDRLPKHQKRENGKKLRDNNNIIFQEKFKAFQDQLMKDIEEKC----ESMTATHRLKICELELSLMKEKHQKLSKYNKEKANLEMDQCQSSYQLENQQKKEMFMLGKSQVKHRQEKEIEHLEKNNKKELDELDYIQQNEKKTFPRFIKNTSRTRNIQKKAELEI 2405
M+F + K FK K KK Y ++ + +P E W+++GE+GDGAFGKV+K ++ LK + +LE + E +I CK + L L++LH + +IHRD+KAGN+L++ D DVKLADFGVSAK Q+R++ GTPYWMAPEV+ C+ + + YD +AD+WS G+TL+E+AQ+ PP+H++ P RVL+KIAK++PPTL +PS WS F +LK+CL K + R LL PF VS +S+K +++ + E + + LK L P+ +D+ SE D + S + ET N +D ++K S L DN ++ + +E+ + + E PC I+ ++N SI A M D D+ N S+ F K KES + ++ + ++ KT+ KTRKFIVDG E++ TT+K+V + ++K+ + R+ E+REL+LL KEE R ++ L K+L +R+ + R + + + ++ ++ +++NL K K +E LE ++ L + KR+ ++ K+ + F+N K +E + + K Q+ +G II Q+K + + +IE C + + I ELE ++EKHQ L QQ K+ + + + Q+ R EKE+E +++ N++ ++EL Q E+ P+ ++ ++TR K L I
Sbjct: 1 MSFF-NFRKIFKLGGDKKKKQYEHVKRDQNPEEYWEIVGELGDGAFGKVYKVSSQH----GQLKLIF--SFAELERALTEPQIRVVCK--------------------------------------------------QTLEALVYLHESKIIHRDLKAGNILLTLDGDVKLADFGVSAKNTRTLQRRDSFIGTPYWMAPEVVMCETSKDRPYDFKADVWSLGVTLIEMAQIEPPHHELNPMRVLLKIAKSEPPTLAQPSRWSPEFNDYLKKCLEKNVDARWTTTQLLQHPF-VSVVNSNKPLRELIAEAKAEVLEEVEDAKEDEEEDEGESSLVSMVLKFKFFILEPAGQINDVLPSEGDAQVMNSEESKETNKDIHDNNVDVLNKIPDSVSHLNTDLEQSCDNTVNVSVAAESSSAT-------VHERQPCVPSISVISADQKENT----SSISTAEASKSEPEHTDSDSGMGSTNDSGSMDL--NLSISSFLSK----GKESGSLSVQDNRRQ-KKTLKKTRKFIVDGVEVSVTTSKIVTDN-DSKSEEMRFLRRQELRELRLLQKEEQRAQQLLSNKLLQQREQIFKRFEQEMTSKKRQYDQDIENLEKQQKQTIERLEQEHTTRLRDEAKRIKGEQDKEYSKFQNVLKNRKKEEQEFVQKQQQELDG----SLKKIIHQQKTE------LANIERDCLNHKQQLMRAREAAIWELEERHLQEKHQLL----------------------KQQLKDQYFMQRHQLLKRHEKEMEQMQRYNQRLIEELKNRQTQERARLPKIQRSDAKTRMAMFKKSLRI 714
BLAST of Serine/threonine-protein kinase 10 vs. Ensembl Mouse
Match: Stk10 (serine/threonine kinase 10 [Source:MGI Symbol;Acc:MGI:1099439]) HSP 1 Score: 338.961 bits (868), Expect = 1.512e-100 Identity = 150/295 (50.85%), Postives = 207/295 (70.17%), Query Frame = 3
Query: 87 MAF--IRDLFKRFKANDPKTKKSYSYLNK-CDPNEVWDVIGEIGDGAFGKVFKAKNKSTDDIAALKQVNLEEEGDLEEYIVEIEILTECKHANVVNLYNAYHFESKLWMALEYCNGGALDSLMITLDKNLNEKAIKYTSKEILSGLIFLHTNGVIHRDMKAGNVLVSKDADVKLADFGVSAKLAADKQKRNTVQGTPYWMAPEVIACQNM-ESYYDCRADIWSFGITLMELAQMRPPYHQMQPTRVLIKIAKADPPTLDRPSLWSSAFISFLKRCLTKKPEDRPHGPDLLSDPFI 959
MAF R + R + + + Y ++ + DPN+VW+++GE+GDGAFGKV+KAKNK T +AA K + + E +LE+YIVEIEIL C H +V L AY+++ KLW+ +E+C GGA+D++M+ LD+ L E I+ +++L L FLH +IHRD+KAGNVL++ + D++LADFGVSAK QKR++ GTPYWMAPEV+ C+ M ++ YD +ADIWS GITL+E+AQ+ PP+H++ P RVL+KIAK+DPPTL PS WS F FLK L K PE RP LL PF+
Sbjct: 1 MAFANFRRIL-RLSTFEKRKSREYEHVRRDLDPNDVWEIVGELGDGAFGKVYKAKNKETGALAAAKVIETKSEEELEDYIVEIEILATCDHPYIVKLLGAYYYDGKLWIMIEFCPGGAVDAIMLELDRGLTEPQIQVVCRQMLEALNFLHGKRIIHRDLKAGNVLMTLEGDIRLADFGVSAKNLKTLQKRDSFIGTPYWMAPEVVLCETMKDAPYDYKADIWSLGITLIEMAQIEPPHHELNPMRVLLKIAKSDPPTLLTPSKWSVEFRDFLKIALDKNPETRPSAAQLLQHPFV 294 HSP 2 Score: 105.145 bits (261), Expect = 1.829e-22 Identity = 87/306 (28.43%), Postives = 166/306 (54.25%), Query Frame = 3
Query: 1503 KTMTKTRKFIVDGEEITTTTTKVVREGLENKNRDQIQDRKMEIRELQLLAKEESREKRQLQFKMLSERDNLASRQKSDELTFEKSHETEMDNLNKLHKSKLENLENQNYHELTNYQKRLLADKAKKENDFK---NKEKTEFGKELDRLPKHQKRENGKKLRDNNNIIFQEKFKAFQDQLMKDIEEKCESMTATHRLKICELELSLMKEKHQKLSKYNKEKANLEMD--QCQSSYQLENQQKKEMFMLGKSQVKHRQEKEIEHLEKNNKKELDELDYIQQNEKKTFPRFIKNTSRTRNIQKKAELEI 2405
KT+ +TR+F+VDG E++ TT+K++ E E K+ + R+ E+REL+LL KEE R + QL K + + + R + + +K ++ E++NL + K ++E +E + KR+ ++ + F+ + K E E+++LP+ Q++E+ K+ + ++ Q + F + +D+E +T +R +IC+ E + +K + L ++E A EM+ Q Q +QL QQ K+ + L + + + EKE E +++ N++ +++L QQ EK P+ ++ +TR K L I
Sbjct: 524 KTLKRTRRFVVDGVEVSITTSKIISED-EKKDEEMRFLRRQELRELRLLQKEEHRNQTQLSSKHELQLEQMHKRFEQEINAKKKFYDVELENLERQQKQQVEKMEQDHSVRRKEEAKRIRLEQDRDYAKFQEQLKQMKKEVKSEVEKLPRQQRKESMKQKMEEHSQKKQRLDRDFVAKQKEDLELAMRKLTTENRREICDKERDCLSKKQELLR--DREAALWEMEEHQLQERHQLVKQQLKDQYFLQRHDLLRKHEKEREQMQRYNQRMMEQLKVRQQQEKARLPKIQRSDGKTRMAMYKKSLHI 826
BLAST of Serine/threonine-protein kinase 10 vs. Ensembl Mouse
Match: Slk (STE20-like kinase [Source:MGI Symbol;Acc:MGI:103241]) HSP 1 Score: 329.331 bits (843), Expect = 1.693e-95 Identity = 143/294 (48.64%), Postives = 210/294 (71.43%), Query Frame = 3
Query: 87 MAFIRDLFKRFKANDPKTKKSYSYLNK-CDPNEVWDVIGEIGDGAFGKVFKAKNKSTDDIAALKQVNLEEEGDLEEYIVEIEILTECKHANVVNLYNAYHFESKLWMALEYCNGGALDSLMITLDKNLNEKAIKYTSKEILSGLIFLHTNGVIHRDMKAGNVLVSKDADVKLADFGVSAKLAADKQKRNTVQGTPYWMAPEVIACQ-NMESYYDCRADIWSFGITLMELAQMRPPYHQMQPTRVLIKIAKADPPTLDRPSLWSSAFISFLKRCLTKKPEDRPHGPDLLSDPFIV 962
M+F + K FK K KK Y ++ + +P E W++IGE+GDGAFGKV+KA+NK T+ +AA K ++ + E +LE+Y+VEI+IL C H N+V L +A+++E+ LW+ +E+C GGA+D++M+ L++ L E I+ K+ L L +LH N +IHRD+KAGN+L + D D+KLADFGVSAK Q+R++ GTPYWMAPEV+ C+ + + YD +AD+WS GITL+E+A++ PP+H++ P RVL+KIAK++PPTL +PS WSS F FL++CL K + R LL PF+
Sbjct: 1 MSFF-NFRKIFKLGSEKKKKQYEHVKRDLNPEEFWEIIGELGDGAFGKVYKAQNKETNVLAAAKVIDTKSEEELEDYMVEIDILASCDHPNIVKLLDAFYYENNLWILIEFCAGGAVDAVMLELERPLTESQIQVVCKQTLEALNYLHDNKIIHRDLKAGNILFTLDGDIKLADFGVSAKNTRTIQRRDSFIGTPYWMAPEVVMCETSKDRPYDYKADVWSLGITLIEMAEIEPPHHELNPMRVLLKIAKSEPPTLAQPSKWSSNFKDFLRKCLEKNVDARWTTSQLLQHPFVT 293 HSP 2 Score: 103.219 bits (256), Expect = 9.285e-22 Identity = 97/336 (28.87%), Postives = 171/336 (50.89%), Query Frame = 3
Query: 1410 NESVEKFSIKDEDSDKESNAQAILNRKKSFYKTMTKTRKFIVDGEEITTTTTKVVREGLENKNRDQIQDRKMEIRELQLLAKEESREKRQLQFKMLSERDNLASRQKSDELTFEKSHETEMDNLNKLHKSKLENLENQNYHELTNYQKRLLADKAKKENDFKNKEKTEFGKELDRLPKHQKRENGKKLRDNNNIIFQEKFKAFQDQLMKDIEEKC----ESMTATHRLKICELELSLMKEKHQKLSKYNKEKANLEMDQCQSSYQLENQQKKEMFMLGKSQVKHRQEKEIEHLEKNNKKELDELDYIQQNEKKTFPRFIKNTSRTRNIQKKAELEI 2405
N S+ F K +DS S L + KT+ KTRKFIVDG E++ TT+K+V + ++K + R+ E+REL+LL KEE R ++QL K+ +R+ + R + + L+ ++ ++ E++NL K K +E LE ++ + L + KR+ ++ K+ + F+N K +E + + K Q+ +G + II Q+K + + +IE +C + + I ELE ++EKHQ L QQ K+ + + + Q+ R EKE E +++ N++ ++EL Q E+ P+ ++ ++TR K L I
Sbjct: 762 NLSISSFLSKAKDSGSVS-----LQETRRQKKTLKKTRKFIVDGVEVSVTTSKIVTDS-DSKTEELRFLRRQELRELRLLQKEEQRAQQQLNGKLQQQREQIFRRFEQEMLSKKRQYDQEIENLEKQQKQTIERLEQEHTNRLRDEAKRIKGEQEKELSKFQNVLKNRKKEEQEFVQKQQQELDGSLKK----IIQQQKAE------LANIERECLNNKQQLMRAREAAIWELEERHLQEKHQLL----------------------KQQLKDQYFMQRHQLLKRHEKETEQMQRYNQRLIEELKNRQTQERARLPKIQRSEAKTRMAMFKKSLRI 1059
BLAST of Serine/threonine-protein kinase 10 vs. Ensembl Mouse
Match: Slk (STE20-like kinase [Source:MGI Symbol;Acc:MGI:103241]) HSP 1 Score: 329.331 bits (843), Expect = 2.051e-95 Identity = 143/294 (48.64%), Postives = 210/294 (71.43%), Query Frame = 3
Query: 87 MAFIRDLFKRFKANDPKTKKSYSYLNK-CDPNEVWDVIGEIGDGAFGKVFKAKNKSTDDIAALKQVNLEEEGDLEEYIVEIEILTECKHANVVNLYNAYHFESKLWMALEYCNGGALDSLMITLDKNLNEKAIKYTSKEILSGLIFLHTNGVIHRDMKAGNVLVSKDADVKLADFGVSAKLAADKQKRNTVQGTPYWMAPEVIACQ-NMESYYDCRADIWSFGITLMELAQMRPPYHQMQPTRVLIKIAKADPPTLDRPSLWSSAFISFLKRCLTKKPEDRPHGPDLLSDPFIV 962
M+F + K FK K KK Y ++ + +P E W++IGE+GDGAFGKV+KA+NK T+ +AA K ++ + E +LE+Y+VEI+IL C H N+V L +A+++E+ LW+ +E+C GGA+D++M+ L++ L E I+ K+ L L +LH N +IHRD+KAGN+L + D D+KLADFGVSAK Q+R++ GTPYWMAPEV+ C+ + + YD +AD+WS GITL+E+A++ PP+H++ P RVL+KIAK++PPTL +PS WSS F FL++CL K + R LL PF+
Sbjct: 1 MSFF-NFRKIFKLGSEKKKKQYEHVKRDLNPEEFWEIIGELGDGAFGKVYKAQNKETNVLAAAKVIDTKSEEELEDYMVEIDILASCDHPNIVKLLDAFYYENNLWILIEFCAGGAVDAVMLELERPLTESQIQVVCKQTLEALNYLHDNKIIHRDLKAGNILFTLDGDIKLADFGVSAKNTRTIQRRDSFIGTPYWMAPEVVMCETSKDRPYDYKADVWSLGITLIEMAEIEPPHHELNPMRVLLKIAKSEPPTLAQPSKWSSNFKDFLRKCLEKNVDARWTTSQLLQHPFVT 293 HSP 2 Score: 109.768 bits (273), Expect = 8.425e-24 Identity = 92/335 (27.46%), Postives = 175/335 (52.24%), Query Frame = 3
Query: 1410 NESVEKFSIKDEDSDKESNAQAILNRKKSFYKTMTKTRKFIVDGEEITTTTTKVVREGLENKNRDQIQDRKMEIRELQLLAKEESREKRQLQFKMLSERDNLASRQKSDELTFEKSHETEMDNLNKLHKSKLENLENQNYHELTNYQKRLLADKAKKENDFKN---KEKTEFGKELDRLPKHQKRENGKKLRDNNNIIFQEKFKAFQDQLMKDIEEKCESMTATHRLKICELELSLMKEKHQKLSKYNKEKANLEMDQCQSSYQLENQQKKEMFMLGKSQVKHRQEKEIEHLEKNNKKELDELDYIQQNEKKTFPRFIKNTSRTRNIQKKAELEI 2405
N S+ F K +DS S L + KT+ KTRKFIVDG E++ TT+K+V + ++K + R+ E+REL+LL KEE R ++QL K+ +R+ + R + + L+ ++ ++ E++NL K K +E LE ++ + L + KR+ ++ K+ + F+N K E E+++ P+ +RE K+ ++ + + F + ++++ + + + ++ +E + K Q + LE Q +QL QQ K+ + + + Q+ R EKE E +++ N++ ++EL Q E+ P+ ++ ++TR K L I
Sbjct: 762 NLSISSFLSKAKDSGSVS-----LQETRRQKKTLKKTRKFIVDGVEVSVTTSKIVTDS-DSKTEELRFLRRQELRELRLLQKEEQRAQQQLNGKLQQQREQIFRRFEQEMLSKKRQYDQEIENLEKQQKQTIERLEQEHTNRLRDEAKRIKGEQEKELSKFQNVLKNRKKEVMNEVEKAPRELRRELTKRRKEELAQSQHAQEQEFVQKQQQELDGSLKKIIQQQKAELANIERECLNNKQQLMRAREAAIWELEERHLQEKHQLLKQQLKDQYFMQRHQLLKRHEKETEQMQRYNQRLIEELKNRQTQERARLPKIQRSEAKTRMAMFKKSLRI 1090
BLAST of Serine/threonine-protein kinase 10 vs. Ensembl Mouse
Match: Stk4 (serine/threonine kinase 4 [Source:MGI Symbol;Acc:MGI:1929004]) HSP 1 Score: 247.669 bits (631), Expect = 7.757e-72 Identity = 118/265 (44.53%), Postives = 164/265 (61.89%), Query Frame = 3
Query: 174 PNEVWDVIGEIGDGAFGKVFKAKNKSTDDIAALKQVNLEEEGDLEEYIVEIEILTECKHANVVNLYNAYHFESKLWMALEYCNGGALDSLMITLDKNLNEKAIKYTSKEILSGLIFLHTNGVIHRDMKAGNVLVSKDADVKLADFGVSAKLAADKQKRNTVQGTPYWMAPEVIACQNMESYYDCRADIWSFGITLMELAQMRPPYHQMQPTRVLIKIAKADPPTLDRPSLWSSAFISFLKRCLTKKPEDRPHGPDLLSDPFIVSC 968
P EV+DV+ ++G+G++G V+KA +K T I A+KQV +E DL+E I EI I+ +C +VV Y +Y + LW+ +EYC G++ ++ +K L E I + L GL +LH IHRD+KAGN+L++ + KLADFGV+ +L KRNTV GTP+WMAPEVI E Y+C ADIWS GIT +E+A+ +PPY + P R + I PPT +P LWS F+ F+K+CL K PE R LL PF+ S
Sbjct: 26 PEEVFDVLEKLGEGSYGSVYKAIHKETGQIVAIKQVPVE--SDLQEIIKEISIMQQCDSPHVVKYYGSYFKNTDLWIVMEYCGAGSVSDIIRLRNKTLTEDEIATILQSTLKGLEYLHFMRKIHRDIKAGNILLNTEGHAKLADFGVAGQLTDTMAKRNTVIGTPFWMAPEVI----QEIGYNCVADIWSLGITAIEMAEGKPPYADIHPMRAIFMIPTNPPPTFRKPELWSDNFMDFVKQCLVKSPEQRATATQLLQHPFVKSA 284
BLAST of Serine/threonine-protein kinase 10 vs. Ensembl Mouse
Match: Stk3 (serine/threonine kinase 3 [Source:MGI Symbol;Acc:MGI:1928487]) HSP 1 Score: 245.743 bits (626), Expect = 4.966e-71 Identity = 118/262 (45.04%), Postives = 161/262 (61.45%), Query Frame = 3
Query: 174 PNEVWDVIGEIGDGAFGKVFKAKNKSTDDIAALKQVNLEEEGDLEEYIVEIEILTECKHANVVNLYNAYHFESKLWMALEYCNGGALDSLMITLDKNLNEKAIKYTSKEILSGLIFLHTNGVIHRDMKAGNVLVSKDADVKLADFGVSAKLAADKQKRNTVQGTPYWMAPEVIACQNMESYYDCRADIWSFGITLMELAQMRPPYHQMQPTRVLIKIAKADPPTLDRPSLWSSAFISFLKRCLTKKPEDRPHGPDLLSDPFI 959
P EV+DV+ ++G+G++G VFKA +K + + A+KQV +E DL+E I EI I+ +C VV Y +Y + LW+ +EYC G++ ++ +K L E I K L GL +LH IHRD+KAGN+L++ + KLADFGV+ +L KRNTV GTP+WMAPEVI E Y+C ADIWS GIT +E+A+ +PPY + P R + I PPT +P LWS F F+K+CL K PE R LL PFI
Sbjct: 21 PEEVFDVLEKLGEGSYGSVFKAIHKESGQVVAIKQVPVE--SDLQEIIKEISIMQQCDSPYVVKYYGSYFKNTDLWIVMEYCGAGSVSDIIRLRNKTLTEDEIATILKSTLKGLEYLHFMRKIHRDIKAGNILLNTEGHAKLADFGVAGQLTDTMAKRNTVIGTPFWMAPEVIQ----EIGYNCVADIWSLGITSIEMAEGKPPYADIHPMRAIFMIPTNPPPTFRKPELWSDDFTDFVKKCLVKSPEQRATATQLLQHPFI 276
BLAST of Serine/threonine-protein kinase 10 vs. UniProt/SwissProt
Match: sp|E9PTG8|STK10_RAT (Serine/threonine-protein kinase 10 OS=Rattus norvegicus OX=10116 GN=Stk10 PE=1 SV=1) HSP 1 Score: 409.453 bits (1051), Expect = 6.043e-126 Identity = 284/838 (33.89%), Postives = 455/838 (54.30%), Query Frame = 3
Query: 87 MAF--IRDLFKRFKANDPKTKKSYSYLNK-CDPNEVWDVIGEIGDGAFGKVFKAKNKSTDDIAALKQVNLEEEGDLEEYIVEIEILTECKHANVVNLYNAYHFESKLWMALEYCNGGALDSLMITLDKNLNEKAIKYTSKEILSGLIFLHTNGVIHRDMKAGNVLVSKDADVKLADFGVSAKLAADKQKRNTVQGTPYWMAPEVIACQNM-ESYYDCRADIWSFGITLMELAQMRPPYHQMQPTRVLIKIAKADPPTLDRPSLWSSAFISFLKRCLTKKPEDRPHGPDLLSDPFIVSCNDSDKHALKVLXXXXXXXXXXX---XXXDLDLKDMRHSLLPSQTFDDISEQDDASVGSSDILETPNVIDTISKSVFSAEILDNI----------ISEQIKSEADKVS----ILGVVVDIMENNPCTNIDDTIAQLDEQNKFDRRRSIRMAMDIVPDI----PISDIKDNESVEKF---------SIKDEDSDKESNAQAI--------------------------LNRKKSFYKTMTKTRKFIVDGEEITTTTTKVVREGLENKNRDQIQDRKMEIRELQLLAKEESREKRQLQFKMLSERDNLASRQKSDELTFEKSHETEMDNLNKLHKSKLENLENQNYHELTNYQKRLLADKAKKENDFK---NKEKTEFGKELDRLPKHQKRENGKKLRDNNNIIFQEKFKAFQDQLMKDIEEKCESMTATHRLKICELELSLMKEKHQKLSKYNKEKANLEMD--QCQSSYQLENQQKKEMFMLGKSQVKHRQEKEIEHLEKNNKKELDELDYIQQNEKKTFPRFIKNTSRTRNIQKKAELEI 2405
MAF R + R + + + Y ++ + DPN+VW+++GE+GDGAFGKV+KAKNK T +AA K + + E +LE+YIVEIEIL C H +V L AY+++ KLW+ +E+C GGA+D++M+ LD+ L E I+ +++L L FLH +IHRD+KAGNVL++ + D++LADFGVSAK QKR++ GTPYWMAPEV+ C+ M ++ YD +ADIWS GITL+E+AQ+ PP+H++ P RVL+KIAK+DPPTL PS WS+ F FLK L K PE RP LL PF VS S+K AL+ L+ EA AE +EE ED KD ++ P QD ++ G+ L + ++ S + ++ + + S Q S AD+VS L V V + ++ P + +D I +E+ D+ + A P + P S + VE S+ S + S+ + L K KT+ +TR+F+VDG E++ TT+K++ E E K+ + R+ E+REL+LL KEE R + QL K + + + R + + +K ++ E++NL + K ++E +E + KR+ ++ + F+ + K E + +++ + Q++E+ + +D++ Q + F + +D+E + +TA +R +IC+ E + +K + L ++E A EM+ Q Q +QL QQ K+ + L + + + EKE E +++ N++ +++L QQ EK P+ ++ +TR K L I
Sbjct: 1 MAFANFRRIL-RLSTFEKRKSREYEHVRRDLDPNDVWEILGELGDGAFGKVYKAKNKETGALAAAKVIETKSEEELEDYIVEIEILATCDHPYIVKLLGAYYYDGKLWIMIEFCPGGAVDAIMLELDRGLTEPQIQVVCRQMLEALNFLHGKRIIHRDLKAGNVLMTLEGDIRLADFGVSAKNLKTLQKRDSFIGTPYWMAPEVVLCETMKDAPYDYKADIWSLGITLIEMAQIEPPHHELNPMRVLLKIAKSDPPTLLTPSKWSTEFRDFLKIALDKNPETRPSAAQLLQHPF-VSTVTSNK-ALRELVAEAKAEVMEEIEDGKEDGSEKDAVSAVPPPVNHT----QDSSANGTQPSLNSDKLLQDSSTPLPPSQPQEPVNGPCNQPSGDGSPQNTSPADEVSKNDNGLKVPVPLRKSRPLS-VDARIQVTEEKQITDQAENPSSAASKPPKVNQSRPNSSALETLGVETLANGGLELPGSVTPNHSKRASDCSNLSTSESMDYGTSLSADLSLNKETGSLSLKGSKLHNKTLKRTRRFVVDGVEVSITTSKIISED-EKKDEEMRFLRRQELRELRLLQKEEHRNQTQLSTKHELQLEQMHRRFEQEINAKKKFYDVELENLERQQKQQVEKMEQDHSVRRREEAKRIRLEQDRDYARFQEQLKQMKKEVKRSIEKALRKQRQESMRMGQDSHTQKKQRLDRDFVAKQKEDLELAMKKLTAENRREICDKERDCLNKKQELLR--DREAALWEMEEHQLQERHQLVKQQLKDQYFLQRHDLLRKHEKEREQMQRYNQRMMEQLKVRQQQEKARLPKIQRSDGKTRMAMYKKSLHI 827
BLAST of Serine/threonine-protein kinase 10 vs. UniProt/SwissProt
Match: sp|E1BK52|STK10_BOVIN (Serine/threonine-protein kinase 10 OS=Bos taurus OX=9913 GN=STK10 PE=3 SV=3) HSP 1 Score: 345.125 bits (884), Expect = 5.841e-102 Identity = 152/299 (50.84%), Postives = 208/299 (69.57%), Query Frame = 3
Query: 87 MAF--IRDLFKRFKANDPKTKKSYSYLNK-CDPNEVWDVIGEIGDGAFGKVFKAKNKSTDDIAALKQVNLEEEGDLEEYIVEIEILTECKHANVVNLYNAYHFESKLWMALEYCNGGALDSLMITLDKNLNEKAIKYTSKEILSGLIFLHTNGVIHRDMKAGNVLVSKDADVKLADFGVSAKLAADKQKRNTVQGTPYWMAPEVIACQNM-ESYYDCRADIWSFGITLMELAQMRPPYHQMQPTRVLIKIAKADPPTLDRPSLWSSAFISFLKRCLTKKPEDRPHGPDLLSDPFIVSCN 971
MAF R + R + + + Y ++ + DPNEVW+++GE+GDGAFGKV+KAKNK T +AA K + E +LE+YIVEIEIL C H +V L AY+++ KLW+ +E+C GGA+D++M+ LD+ L E I+ +++L L FLH +IHRD+KAGNVL++ + D++LADFGVSAK QKR++ GTPYWMAPEV+ C+ M ++ YD +ADIWS GITL+E+AQ+ PP+H++ P RVL+KIAK+DPPTL PS WS+ F FLK L K PE RP LL PF+ S
Sbjct: 1 MAFANFRRIL-RLSTFEKRKSREYEHVRRDLDPNEVWEIVGELGDGAFGKVYKAKNKETGALAAAKVIETNSEEELEDYIVEIEILATCDHPYIVKLLGAYYYDGKLWIMIEFCPGGAVDAIMLELDRGLTEPQIQVVCRQMLEALTFLHGKKIIHRDLKAGNVLMTLEGDIRLADFGVSAKNLKTLQKRDSFIGTPYWMAPEVVMCETMKDTPYDYKADIWSLGITLIEMAQIEPPHHELNPMRVLLKIAKSDPPTLLSPSKWSAEFRDFLKTALDKNPETRPSAAQLLEHPFVSSVT 298 HSP 2 Score: 103.99 bits (258), Expect = 3.366e-21 Identity = 88/306 (28.76%), Postives = 166/306 (54.25%), Query Frame = 3
Query: 1503 KTMTKTRKFIVDGEEITTTTTKVVREGLENKNRDQIQDRKMEIRELQLLAKEESREKRQLQFKMLSERDNLASRQKSDELTFEKSHETEMDNLNKLHKSKLENLENQNYHELTNYQKRLLADKAKKENDFKNK---EKTEFGKELDRLPKHQKRENGKKLRDNNNIIFQEKFKAFQDQLMKDIEEKCESMTATHRLKICELELSLMKEKHQKLSKYNKEKANLEMDQ--CQSSYQLENQQKKEMFMLGKSQVKHRQEKEIEHLEKNNKKELDELDYIQQNEKKTFPRFIKNTSRTRNIQKKAELEI 2405
KT+ +TRKF+VDG E++ TT+K++ E E K+ + R+ E+REL+LL KEE R + QL K + + + R + + +K + E++NL + K ++E +E + KR+ ++ + F+ + K E E+++LP+ Q++E+ K+ + + Q + F + +D+E + +TA +R +IC+ E + K + L ++E A EM++ Q +QL QQ K+ + L + ++ + EKE E +++ N++ +++L QQ EK P+ ++ +TR K L I
Sbjct: 523 KTLKRTRKFVVDGVEVSITTSKIISED-EKKDEEMRFLRRQELRELRLLQKEEHRNQTQLSSKHELQLEQMHKRFEQEINAKKKFFDIELENLERQQKQQVEKMEQDHAVRRREEAKRIRLEQERDYAKFQEQLKLMKKEVKNEVEKLPRQQRKESMKQKMEEHTQKKQLLDRDFLAKQKEDLELAMKRITADNRREICDKERECLTRKQELLR--DREAALWEMEEHHLQERHQLVKQQLKDQYFLQRHELLRKHEKEREQMQRYNQRMIEQLKVRQQQEKARLPKIQRSEGKTRMAMYKKSLHI 825
BLAST of Serine/threonine-protein kinase 10 vs. UniProt/SwissProt
Match: sp|F1NBT0|STK10_CHICK (Serine/threonine-protein kinase 10 OS=Gallus gallus OX=9031 GN=STK10 PE=3 SV=2) HSP 1 Score: 344.354 bits (882), Expect = 1.234e-101 Identity = 152/295 (51.53%), Postives = 208/295 (70.51%), Query Frame = 3
Query: 87 MAF--IRDLFKRFKANDPKTKKSYSYLNK-CDPNEVWDVIGEIGDGAFGKVFKAKNKSTDDIAALKQVNLEEEGDLEEYIVEIEILTECKHANVVNLYNAYHFESKLWMALEYCNGGALDSLMITLDKNLNEKAIKYTSKEILSGLIFLHTNGVIHRDMKAGNVLVSKDADVKLADFGVSAKLAADKQKRNTVQGTPYWMAPEVIACQNM-ESYYDCRADIWSFGITLMELAQMRPPYHQMQPTRVLIKIAKADPPTLDRPSLWSSAFISFLKRCLTKKPEDRPHGPDLLSDPFI 959
MAF R + R + + K Y ++ + DP EVW+V+GE+GDGAFGKV+KAKNK T +AA K + + E +LE+Y+VEIEIL C H ++V L A+++E KLW+ +E+C GGA+D+ M+ LD+ L E I+ +++L L +LH+ +IHRD+KAGNVL+++D D+KLADFGVSAK QKR++ GTPYWMAPEV+ C+ M ++ YD +ADIWS GITL+E+AQ+ PP+H++ P RVL+KIAK+DPPTL PS WS F FLK L K PE RP LL PF+
Sbjct: 1 MAFANFRRIL-RLSTFEKRRSKEYEHVRRDLDPGEVWEVVGELGDGAFGKVYKAKNKETGALAAAKVIETKNEDELEDYMVEIEILATCDHPHIVKLLGAFYWEGKLWIMIEFCPGGAVDATMLELDRGLTEPQIQVICRQMLEALHYLHSKKIIHRDLKAGNVLLTQDGDIKLADFGVSAKNVKTLQKRDSFIGTPYWMAPEVVMCETMKDTPYDYKADIWSLGITLIEMAQIEPPHHELNPMRVLLKIAKSDPPTLSCPSKWSLEFRDFLKTALDKNPETRPSAAQLLEHPFV 294 HSP 2 Score: 114.39 bits (285), Expect = 2.107e-24 Identity = 94/307 (30.62%), Postives = 166/307 (54.07%), Query Frame = 3
Query: 1503 KTMTKTRKFIVDGEEITTTTTKVVREGLENKNRDQIQDRKMEIRELQLLAKEESREKRQLQFKMLSERDNLASRQKSDELTFEKSHETEMDNLNKLHKSKLENLENQNYHELTNYQKRLLADKAKKENDFK---NKEKTEFGKELDRLPKHQKRENGKKLRDNNNIIFQEKFKAFQDQLMK---DIEEKCESMTATHRLKICELELSLMKEKHQKLSKYNKEKANLEMDQCQSSYQLENQQKKEMFMLGKSQVKHRQEKEIEHLEKNNKKELDELDYIQQNEKKTFPRFIKNTSRTRNIQKKAELEI 2405
KT+ +TRKF+VDG E++ TT+K++ E E K+ + R+ E+REL+LL KEE R + QL K + D + R + + +K ++TE++NL + K ++E +E + KR+ ++ + F ++K E E+++LP+ Q++EN K D+ Q K QD L K D+E +++TA ++ +IC+ E + +K Q + +LE Q Q +QL QQ K+ + L + ++ + EKE E +++ N++ +++L QQ EK P+ ++ +TR K L I
Sbjct: 526 KTLKRTRKFVVDGVEVSVTTSKIISED-EKKDEEMRFLRRQELRELRLLQKEEHRNQAQLNSKHQLQLDQMLRRFEQEMTAKKKFYDTELENLERQQKQQIEKMEQDHSLRRREEAKRIRLEQERDHVKFMEQLKQKKKEVKNEVEKLPRQQRKENMKVKMDD---FAQRKQTMEQDFLAKQKEDLELAMKNITAQNKKEICDKERECLNKKQQLMRDREACIWDLEERQQQEKHQLIKQQLKDQYFLQRHELLRKHEKEREQMQRYNQRMIEQLKIRQQQEKARLPKIQRSEGKTRMAMYKKSLHI 828
BLAST of Serine/threonine-protein kinase 10 vs. UniProt/SwissProt
Match: sp|Q0IHQ8|STK10_XENTR (Serine/threonine-protein kinase 10 OS=Xenopus tropicalis OX=8364 GN=stk10 PE=2 SV=1) HSP 1 Score: 341.658 bits (875), Expect = 8.898e-101 Identity = 148/280 (52.86%), Postives = 205/280 (73.21%), Query Frame = 3
Query: 144 KSYSYLNK-CDPNEVWDVIGEIGDGAFGKVFKAKNKSTDDIAALKQVNLEEEGDLEEYIVEIEILTECKHANVVNLYNAYHFESKLWMALEYCNGGALDSLMITLDKNLNEKAIKYTSKEILSGLIFLHTNGVIHRDMKAGNVLVSKDADVKLADFGVSAKLAADKQKRNTVQGTPYWMAPEVIACQNM-ESYYDCRADIWSFGITLMELAQMRPPYHQMQPTRVLIKIAKADPPTLDRPSLWSSAFISFLKRCLTKKPEDRPHGPDLLSDPFI--VSCN 971
+ Y ++ + DPN+VW++IGE+GDGAFGKV+KAKNK T +AA K + + E +LE+Y+VEIEIL C H +V L +Y++E KLW+ +E+C GGA+D++M+ LD+ L E I+ +++L GL +LH+ +IHRD+KAGNVL++ D D+KLADFGVSAK Q+R++ GTPYWMAPEV+ C+ M ++ YD +ADIWS GITL+E+AQ+ PP+H++ P RVL+KIAK++PPTL PS WS F +FLK L K PE RP LL PF+ VS N
Sbjct: 21 REYEHVRRDLDPNQVWEIIGELGDGAFGKVYKAKNKETGILAAAKVIETKNEEELEDYMVEIEILATCNHHFIVKLLGSYYWEGKLWIMIEFCPGGAVDAIMLELDRGLKEPEIRTICRQMLEGLTYLHSMKMIHRDLKAGNVLLTLDGDIKLADFGVSAKNVKTLQRRDSFIGTPYWMAPEVVMCETMKDAPYDYKADIWSLGITLIEMAQIEPPHHELNPMRVLLKIAKSEPPTLSSPSKWSPEFHNFLKTALDKNPETRPSAAQLLEHPFVKKVSGN 300 HSP 2 Score: 85.5001 bits (210), Expect = 1.762e-15 Identity = 82/310 (26.45%), Postives = 156/310 (50.32%), Query Frame = 3
Query: 1503 KTMTKTRKFIVDGEEITTTTTKVVREGLENKNRDQIQDRKMEIRELQLLAKEESREKRQLQFKMLSERDNLASRQKSDELTFEKSHETEMDNLNKLHKSKLENLENQNYHELTNYQKRLLADKAKKENDFKNKE-----KTEFGKELDRLPKHQKRENGKKLRDNNNIIFQEKFKAFQDQLM----KDIEEKCESMTATHRLKICELELSLMKEKHQKLSKYNKEKANLEMDQCQSSYQLENQQKKEMFMLGKSQVKHRQEKEIEHLEKNNKKELDELDYIQQNEKKTFPRFIKNTSRTRNIQKKAELEI 2405
KT+ +TR+F+VDG E++ TT+K++ + E K+ + R+ E+REL+LL KEE R + QL K + + + R + + + K +++E++ L + K ++E +E + H L + ++ + K E K E ++++LP+ Q+R+ K D+ F +K + Q + +D+ + +R +I E + +K Q L +LE Q +QL QQ K+ + L + ++ + EKE E +++ N++ +++L QQ E+ P+ K ++TR K L I
Sbjct: 509 KTLKRTRRFVVDGVEVSITTSKIIGDD-EKKDEEMRFLRRQELRELRLLQKEEHRNQAQLTSKHSFQMEQMLRRFEQEMNSKRKFYDSELEALERHQKQQIERMEQE--HALRRRDEARRIRTEQERDHVKFLEQLKLRKKELKAQVEKLPRQQRRDAMKVQMDD----FAQKKHIEEQQFLNKQKEDLTLALRVIVLENRKEIYNKEREFLNKKQQLLRDREAVIWDLEERHLQERHQLVKQQLKDQYFLQRHELLRKHEKEQEQMQRYNQRMMEQLKLRQQQERARLPKNQKAEAKTRMTMFKKSLHI 811
BLAST of Serine/threonine-protein kinase 10 vs. UniProt/SwissProt
Match: sp|O94804|STK10_HUMAN (Serine/threonine-protein kinase 10 OS=Homo sapiens OX=9606 GN=STK10 PE=1 SV=1) HSP 1 Score: 340.117 bits (871), Expect = 4.275e-100 Identity = 152/297 (51.18%), Postives = 208/297 (70.03%), Query Frame = 3
Query: 87 MAF--IRDLFKRFKANDPKTKKSYSYLNK-CDPNEVWDVIGEIGDGAFGKVFKAKNKSTDDIAALKQVNLEEEGDLEEYIVEIEILTECKHANVVNLYNAYHFESKLWMALEYCNGGALDSLMITLDKNLNEKAIKYTSKEILSGLIFLHTNGVIHRDMKAGNVLVSKDADVKLADFGVSAKLAADKQKRNTVQGTPYWMAPEVIACQNM-ESYYDCRADIWSFGITLMELAQMRPPYHQMQPTRVLIKIAKADPPTLDRPSLWSSAFISFLKRCLTKKPEDRPHGPDLLSDPFIVS 965
MAF R + R + + + Y ++ + DPNEVW+++GE+GDGAFGKV+KAKNK T +AA K + + E +LE+YIVEIEIL C H +V L AY+ + KLW+ +E+C GGA+D++M+ LD+ L E I+ +++L L FLH+ +IHRD+KAGNVL++ + D++LADFGVSAK QKR++ GTPYWMAPEV+ C+ M ++ YD +ADIWS GITL+E+AQ+ PP+H++ P RVL+KIAK+DPPTL PS WS F FLK L K PE RP LL PF+ S
Sbjct: 1 MAFANFRRIL-RLSTFEKRKSREYEHVRRDLDPNEVWEIVGELGDGAFGKVYKAKNKETGALAAAKVIETKSEEELEDYIVEIEILATCDHPYIVKLLGAYYHDGKLWIMIEFCPGGAVDAIMLELDRGLTEPQIQVVCRQMLEALNFLHSKRIIHRDLKAGNVLMTLEGDIRLADFGVSAKNLKTLQKRDSFIGTPYWMAPEVVMCETMKDTPYDYKADIWSLGITLIEMAQIEPPHHELNPMRVLLKIAKSDPPTLLTPSKWSVEFRDFLKIALDKNPETRPSAAQLLEHPFVSS 296 HSP 2 Score: 102.449 bits (254), Expect = 8.354e-21 Identity = 95/342 (27.78%), Postives = 179/342 (52.34%), Query Frame = 3
Query: 1395 SDIKDNESVEKFSIKDEDSDKESNAQAILNRKKSFYKTMTKTRKFIVDGEEITTTTTKVVREGLENKNRDQIQDRKMEIRELQLLAKEESREKRQLQFKMLSERDNLASRQKSDELTFEKSHETEMDNLNKLHKSKLENLENQNYHELTNYQKRLLADKAKKENDFKNK---EKTEFGKELDRLPKHQKRENGKKLRDNNNIIFQEKFKAFQDQLMKDIEEKCESMTATHRLKICELELSLMKEKHQKLSKYNKEKANLEMD--QCQSSYQLENQQKKEMFMLGKSQVKHRQEKEIEHLEKNNKKELDELDYIQQNEKKTFPRFIKNTSRTRNIQKKAELEI 2405
+D+ N+ + SIKD K + KT+ +TRKF+VDG E++ TT+K++ E E K+ + R+ E+REL+LL KEE R + QL K + + + R + + +K +TE++NL + K ++E +E + +R+ ++ + F+ + K E E+++LP+ Q++E+ K+ + + Q + F + +D+E + +T +R +IC+ E + +K + L ++E A EM+ Q Q +QL QQ K+ + L + ++ + EKE E +++ N++ +++L QQ EK P+ ++ +TR K L I
Sbjct: 504 TDLSLNKEMGSLSIKD---------------PKLYKKTLKRTRKFVVDGVEVSITTSKIISED-EKKDEEMRFLRRQELRELRLLQKEEHRNQTQLSNKHELQLEQMHKRFEQEINAKKKFFDTELENLERQQKQQVEKMEQDHAVRRREEARRIRLEQDRDYTRFQEQLKLMKKEVKNEVEKLPRQQRKESMKQKMEEHTQKKQLLDRDFVAKQKEDLELAMKRLTTDNRREICDKERECLMKKQELLR--DREAALWEMEEHQLQERHQLVKQQLKDQYFLQRHELLRKHEKEREQMQRYNQRMIEQLKVRQQQEKARLPKIQRSEGKTRMAMYKKSLHI 827
BLAST of Serine/threonine-protein kinase 10 vs. TrEMBL
Match: A0A4S2LQ13 (Protein kinase domain-containing protein OS=Opisthorchis felineus OX=147828 GN=CRM22_007252 PE=4 SV=1) HSP 1 Score: 451.44 bits (1160), Expect = 2.190e-139 Identity = 295/924 (31.93%), Postives = 504/924 (54.55%), Query Frame = 3
Query: 87 MAFIRDLFKRFKANDPKTKKSYSYLNKC----DPNEVWDVIGEIGDGAFGKVFKAKNKSTDDIAALKQVNLEEEGDLEEYIVEIEILTECKHANVVNLYNAYHFESKLWMALEYCNGGALDSLMITLDKNLNEKAIKYTSKEILSGLIFLHTNGVIHRDMKAGNVLVSKDADVKLADFGVSAKLAADKQKRNTVQGTPYWMAPEVIACQNM-ESYYDCRADIWSFGITLMELAQMRPPYHQMQPTRVLIKIAKADPPTLDRPSLWSSAFISFLKRCLTKKPEDRPHGPDLLSDPFIVSCNDSDKHALKVLXXXXXX----XXXXXXXXDLD------------LKDMRHSLLPSQTFDDISEQDDASVGSSDIL-------------ETPNVIDTISKSVFSAEILDNIISEQIKSEADKVSILGVVVDIMENNPCTNIDDTIAQLDEQNKFDRRRSIRMAMDIVPDIPISDIKDNESVEKFSIKDEDSDKESNAQAILNRKKSFYKTMTKTRKFIVDGEEITTTTTKVVREGLE--NKNRDQIQDRKMEIRELQLLAKEESREKRQLQFKMLSERDNLASRQKSDELTFEKSHETEMDNLNKLHKSKLENLENQNYHELTNYQKRLLADKAKKENDFKNKEKTEFGKELDRLPKHQKRENGKKLRDNNNI--------------------------IFQEKFKAFQDQLMKDIEEKCESMTATHRLKICELELSLMKEKHQKLSKYNKEKANLEMDQCQSSYQLENQQKKEMFMLGKSQVKHRQEKEIEHLEKNNKKELDELDYIQQNEKKTFPRFIKNTSRTRNIQKKAELEIQLQRNL---ISSADMXXXXXXXXXXXXXXXXXXXXXMNSKLTKKRDAMLAEHFQRRREFEQIHAEQKNELSNQETLFLREIEKRHKNDI 2663
MAF++ L ++ K D KKS L+K DP+EVW+VIGE+GDGA+GKV+KAK + + + ALK+V + E LE+++VEI+ILTE KH N+++L Y ++SKLWM LE C+GGALDS+M TL+K LNE+ I++ ++E+L+GL FLH N +IHRDMKAGN+L++ +VKLADFGVSA LA +KQKR+T G+PYWMAPEVIAC+ + ES Y+ +AD+WSFGITL+ELAQMRPPY+ + PTRVL+KI K+DPPTL +P WS+ F L RCL K P R +LLSDPF+ + ++ D+ +K+L+ E A E +LD L D +P + D+ E D+ + + L P D + ++ D +ISE + SE S+ + ++M R I +D+ IP D ++ + + K + L+R+ S +K++T+TR+F+VDG+ +TTTT ++ E + + + RK E+R ++L K+E+R+ R+L K + +++ L ++ ++ L ++ +E +++ +++ ++++LE LE E KR+ + K+ FK + KELD+ + +++ ++L +N++ + ++ +F++Q + +T + ++ L + EKH + +EK +E +QL + ++ F + + ++ E E+ L + +E ++L+ I E+K +++K N+QKK + L ++++ +K +L+EFEE +++ + KL ++++ + R +E EQ H++++N+L++ ET LRE++++H+ ++
Sbjct: 1 MAFLKGLLRKIKGPDEVKKKSS--LDKVRRDIDPDEVWEVIGELGDGAYGKVYKAKQRKGETLTALKKVEFDSEVALEDFMVEIDILTEFKHPNIISLLEVYIYDSKLWMFLELCDGGALDSIMTTLEKPLNERQIRFVAREVLAGLKFLHENLIIHRDMKAGNILLTSANEVKLADFGVSAFLANEKQKRDTFIGSPYWMAPEVIACEALKESPYNWKADVWSFGITLIELAQMRPPYNDINPTRVLLKITKSDPPTLAKPRFWSNEFSDLLSRCLQKDPNKRAECSELLSDPFVANLSEKDRECIKLLMCELKADVIDTVEESDSVELDDEEEHAEENVLILPDSTKIEVPMEVVDEDEENYDSETKAKEELLDLDRATEDQPFEVVPQKPDESLLRDLAQDLTDQLISEVVTSETRHPSVPSCLFEVM------------------------RDISEEVDVRQTIPEEDRLPSQPI---------APKPPASGPKLSRRASAHKSLTRTRRFVVDGKVVTTTTKHIIPANAEVLKQREEDLNSRKAELRAFRMLGKQEARQTRELTAKAIQQKEQLETKLATEFLALKRGYEQKLELVSRNYRAQLERLEK----EYETDSKRIRSTTVKEGQTFKE----QLRKELDKCSRAERKIAMRELNSDNSMFPGGSMSLSASLTSLNSLHSNSSQKSVISQQLLSFREQQGVRFTSHMKQLTLAFQERLYHLREEELVEKHTIRMNFEQEKWKMEQRHMHMRHQLSRSKLQDFFSIKRQKLAGLLELELYELRQTITREREKLNTIHAIERKNHAKYVK------NMQKKNMTDFHRHCRLDSSLTTSRLKERLREFEEATRKQLGDETYEFEQKLQRQQELLEYSIVVRLKELEQSHSDKRNDLTDLETERLRELDEKHEYEL 875
BLAST of Serine/threonine-protein kinase 10 vs. TrEMBL
Match: A0A4S2LIW6 (Protein kinase domain-containing protein OS=Opisthorchis felineus OX=147828 GN=CRM22_007252 PE=4 SV=1) HSP 1 Score: 440.269 bits (1131), Expect = 7.028e-135 Identity = 270/820 (32.93%), Postives = 446/820 (54.39%), Query Frame = 3
Query: 87 MAFIRDLFKRFKANDPKTKKSYSYLNKC----DPNEVWDVIGEIGDGAFGKVFKAKNKSTDDIAALKQVNLEEEGDLEEYIVEIEILTECKHANVVNLYNAYHFESKLWMALEYCNGGALDSLMITLDKNLNEKAIKYTSKEILSGLIFLHTNGVIHRDMKAGNVLVSKDADVKLADFGVSAKLAADKQKRNTVQGTPYWMAPEVIACQNM-ESYYDCRADIWSFGITLMELAQMRPPYHQMQPTRVLIKIAKADPPTLDRPSLWSSAFISFLKRCLTKKPEDRPHGPDLLSDPFIVSCNDSDKHALKVLXXXXXX----XXXXXXXXDLD------------LKDMRHSLLPSQTFDDISEQDDASVGSSDIL-------------ETPNVIDTISKSVFSAEILDNIISEQIKSEADKVSILGVVVDIMENNPCTNIDDTIAQLDEQNKFDRRRSIRMAMDIVPDIPISDIKDNESVEKFSIKDEDSDKESNAQAILNRKKSFYKTMTKTRKFIVDGEEITTTTTKVVREGLE--NKNRDQIQDRKMEIRELQLLAKEESREKRQLQFKMLSERDNLASRQKSDELTFEKSHETEMDNLNKLHKSKLENLENQNYHELTNYQKRLLADKAKKENDFKNKEKTEFGKELDRLPKHQKRENGKKLRDNNNI--------------------------IFQEKFKAFQDQLMKDIEEKCESMTATHRLKICELELSLMKEKHQKLSKYNKEKANLEMDQCQSSYQLENQQKKEMFMLGKSQVKHRQEKEIEHLEKNNKKELDELDYIQQNEKKTFPRFIKN 2360
MAF++ L ++ K D KKS L+K DP+EVW+VIGE+GDGA+GKV+KAK + + + ALK+V + E LE+++VEI+ILTE KH N+++L Y ++SKLWM LE C+GGALDS+M TL+K LNE+ I++ ++E+L+GL FLH N +IHRDMKAGN+L++ +VKLADFGVSA LA +KQKR+T G+PYWMAPEVIAC+ + ES Y+ +AD+WSFGITL+ELAQMRPPY+ + PTRVL+KI K+DPPTL +P WS+ F L RCL K P R +LLSDPF+ + ++ D+ +K+L+ E A E +LD L D +P + D+ E D+ + + L P D + ++ D +ISE + SE S+ + ++M R I +D+ IP D ++ + + K + L+R+ S +K++T+TR+F+VDG+ +TTTT ++ E + + + RK E+R ++L K+E+R+ R+L K + +++ L ++ ++ L ++ +E +++ +++ ++++LE LE E KR+ + K+ FK + KELD+ + +++ ++L +N++ + ++ +F++Q + +T + ++ L + EKH + +EK +E +QL + ++ F + + ++ E E+ L + +E ++L+ I E+K +++KN
Sbjct: 1 MAFLKGLLRKIKGPDEVKKKSS--LDKVRRDIDPDEVWEVIGELGDGAYGKVYKAKQRKGETLTALKKVEFDSEVALEDFMVEIDILTEFKHPNIISLLEVYIYDSKLWMFLELCDGGALDSIMTTLEKPLNERQIRFVAREVLAGLKFLHENLIIHRDMKAGNILLTSANEVKLADFGVSAFLANEKQKRDTFIGSPYWMAPEVIACEALKESPYNWKADVWSFGITLIELAQMRPPYNDINPTRVLLKITKSDPPTLAKPRFWSNEFSDLLSRCLQKDPNKRAECSELLSDPFVANLSEKDRECIKLLMCELKADVIDTVEESDSVELDDEEEHAEENVLILPDSTKIEVPMEVVDEDEENYDSETKAKEELLDLDRATEDQPFEVVPQKPDESLLRDLAQDLTDQLISEVVTSETRHPSVPSCLFEVM------------------------RDISEEVDVRQTIPEEDRLPSQPI---------APKPPASGPKLSRRASAHKSLTRTRRFVVDGKVVTTTTKHIIPANAEVLKQREEDLNSRKAELRAFRMLGKQEARQTRELTAKAIQQKEQLETKLATEFLALKRGYEQKLELVSRNYRAQLERLEK----EYETDSKRIRSTTVKEGQTFKE----QLRKELDKCSRAERKIAMRELNSDNSMFPGGSMSLSASLTSLNSLHSNSSQKSVISQQLLSFREQQGVRFTSHMKQLTLAFQERLYHLREEELVEKHTIRMNFEQEKWKMEQRHMHMRHQLSRSKLQDFFSIKRQKLAGLLELELYELRQTITREREKLNTIHAIERKNHAKYVKN 777
BLAST of Serine/threonine-protein kinase 10 vs. TrEMBL
Match: A0A1V4KU24 (Serine/threonine-protein kinase 10 OS=Patagioenas fasciata monilis OX=372326 GN=STK10 PE=4 SV=1) HSP 1 Score: 422.55 bits (1085), Expect = 1.968e-128 Identity = 289/836 (34.57%), Postives = 451/836 (53.95%), Query Frame = 3
Query: 87 MAF--IRDLFKRFKANDPKTKKSYSYLNK-CDPNEVWDVIGEIGDGAFGKVFKAKNKSTDDIAALKQVNLEEEGDLEEYIVEIEILTECKHANVVNLYNAYHFESKLWMALEYCNGGALDSLMITLDKNLNEKAIKYTSKEILSGLIFLHTNGVIHRDMKAGNVLVSKDADVKLADFGVSAKLAADKQKRNTVQGTPYWMAPEVIACQNM-ESYYDCRADIWSFGITLMELAQMRPPYHQMQPTRVLIKIAKADPPTLDRPSLWSSAFISFLKRCLTKKPEDRPHGPDLLSDPFIVSCNDSDKHALKVLXXXXXXXXXXXXXXDLDLKDMRHSLLPSQTFDDISEQDDASVGSSDILETPNVIDTISKSVFSAEILDN------------IISEQIKSEADKVSILGVVV--DIMENNPCTNIDDTIAQLDEQNKFD----------RRRSI------------------RMAMDIVPDIPISDIK-DNESVEKFSIKDEDSDKESNAQAILNRK---------KSFYKTMTKTRKFIVDGEEITTTTTKVVREGLENKNRDQIQDRKMEIRELQLLAKEESREKRQLQFKMLSERDNLASRQKSDELTFEKSHETEMDNLNKLHKSKLENLENQNYHELTNYQKRLLADKAKKENDF---KNKEKTEFGKELDRLPKHQKRENGKKLRDNNNIIFQEKFKAFQDQLM----KDIEEKCESMTATHRLKICELELSLMKEKHQKLSKYNKEKANLEMDQCQSSYQLENQQKKEMFMLGKSQVKHRQEKEIEHLEKNNKKELDELDYIQQNEKKTFPRFIKNTSRTRNIQKKAELEI 2405
MAF R + R + + K Y ++ + DP EVW+V+GE+GDGAFGKV+KAKNK T +AA K + + E +LE+Y+VEIEIL C H ++V L A++++ KLW+ +E+C GGA+D+ M+ LD+ L E I+ +++L L +LH +IHRD+KAGNVL+++D D+KLADFGVSAK QKR++ GTPYWMAPEV+ C+ M ++ YD +ADIWS GITL+E+AQ+ PP+H++ P RVL+KIAK+DPPTL PS WS F FLK L K PE RP LL PF+ + AL+ L+ EA AE +E +++D R D +E DD+S +S + S+ F E L + E ++DKVS G+ D +E+N T + A Q K D R+SI ++D P S K D++S + + D +A LNR+ + KT+ +TRKF+VDG E++ TT+K++ E E K+ + R+ E+REL+LL KEE R + QL K + + + R + + T +K ++TE++NL + K ++E +E + KR+ ++ + F + K E E+++LP+ Q++ N K D+ F +K + + + + +D+E +++TA ++ +IC+ E + +K Q + +LE Q Q +QL QQ K+ + L + ++ + EKE E +++ N++ L++L QQ EK P+ ++ +TR K L I
Sbjct: 1 MAFANFRRIL-RLSTFEKRRSKEYEHVRRDLDPGEVWEVVGELGDGAFGKVYKAKNKETGALAAAKVIETKSEDELEDYMVEIEILATCDHRHIVKLLGAFYWDGKLWIMIEFCPGGAVDATMLELDRGLTEPQIQVICRQMLEALHYLHGKKIIHRDLKAGNVLLTQDGDIKLADFGVSAKNTKTLQKRDSFIGTPYWMAPEVVMCETMKDTPYDYKADIWSLGITLIEMAQIEPPHHELNPMRVLLKIAKSDPPTLSCPSKWSLEFRDFLKTALDKNPETRPSAAQLLEHPFVSKVTSN--RALRELVAEAKAEVME------EIEDSR----------DEAEDDDSSESASPPGKHKRDPSEASQLSFDGEKLPDSSLPKAANGSVGTGKETTDLKSDKVSDEGISRDNDKLESNDSTKTLASSATSATQGKPDIISQPRPGSKERKSIGERPESSHLENFPEEKLANGSLDPAAPFPGSRSKGDSDSGSTSASESMDLTISLSADLSLNRESGSISLKDSRMHKKTLKRTRKFVVDGVEVSVTTSKIISED-EKKDEEMRFLRRQELRELRLLQKEEHRNQAQLNSKHQLQLEQMFRRFEQEMTTKKKFYDTELENLERQQKQQIEKMEQDHSLRRREEAKRIRLEQERDHVKFLEQLKQMKKEVKNEVEKLPRQQRKGNMKVKMDD----FAQKKQTMEQEFLAKQKEDLELAMKNITAQNKKEICDKERECLNKKQQLMRDREACIWDLEEHQQQEKHQLIKQQLKDQYFLQRHELLRKHEKEREQMQRYNQRMLEQLRIRQQQEKARLPKIQRSEGKTRMTMYKKSLHI 812
BLAST of Serine/threonine-protein kinase 10 vs. TrEMBL
Match: A0A4Z2DNS4 (Serine/threonine-protein kinase 10 isoform 1 OS=Schistosoma japonicum OX=6182 GN=EWB00_010593 PE=4 SV=1) HSP 1 Score: 420.624 bits (1080), Expect = 1.343e-127 Identity = 298/908 (32.82%), Postives = 491/908 (54.07%), Query Frame = 3
Query: 105 LFKRFKANDPKTKKSYS--YLNKCDPNEVWDVIGEIGDGAFGKVFKAKNKSTDDIAALKQVNLEEEGDLEEYIVEIEILTECKHANVVNLYNAYHFESKLWMALEYCNGGALDSLMITLDKNLNEKAIKYTSKEILSGLIFLHTNGVIHRDMKAGNVLVSKDADVKLADFGVSAKLAADKQKRNTVQGTPYWMAPEVIACQNM-ESYYDCRADIWSFGITLMELAQMRPPYHQMQPTRVLIKIAKADPPTLDRPSLWSSAFISFLKRCLTKKPEDRPHGPDLLSDPFIVSCNDSDKHALKVLXXXXXXXXXXXXXXDLDLKDMRHSLLPSQTFDDI--SEQDDASVGSSDILETPNVIDTISKSVFSAEILDNIIS-----EQIK--SEADKVSILGVVVDIMENNPCTNIDDTIAQLDEQNKFDRRRSIRMAMDIVPDIPISDIKDNESVEKFSIKD--------------EDSDKESNAQAILNRKKSFYKTMTKTRKFIVDGEEITTTTTKVVREGLENKN--RDQIQDRKMEIRELQLLAKEESREKRQLQFKMLSERDNLASRQKSDELTFEKSHETEMDNLNKLHKSKLENLENQNYHELTNYQKRLLADKAKKENDFKNKEKTEFGKELDRLPKHQKRE---------NGKKLRD------------------NNNIIFQEKFKAFQDQLMKDIEEKCESMTATHRLKICELELSLMKEKHQKLSKYNKEKANLEMDQCQSSYQLENQQKKEMFMLGKSQVKHRQEKEIEHLEKNNKKELDELDYIQQNEKKTFPRFIKNTSRTRNIQKKAELEIQLQRNLISSADMXXXXXXXXXXXXXXXXXXXXXMNSKLTKKRDAMLAEHFQRRREFEQIHAEQKNELSNQETLFLREIEKRHKNDI 2663
FKR K+ D KK+YS +P+++W++I E+GDGAFGKV+K + TD AALK+V + E +LE+++VEI+IL+ KH N+++L+ Y ++SKLWM LE C GGALDS+M TL+K L E I++ SKE+L GL FLH +IHRDMKAGN+L++ + +VKLADFGVSA+LA +KQKR T GTPYWMAPEVI C+ ++ Y+ +ADIWSFGITL+ELAQ RPPY+ + PTRVL+KI+K+DPPTL +P LWSS F +FL R L K P RP DLL DPF+ +SD+ +++L + D+ + L P++ DDI +E + + S P +D S E DN+ S E IK ++++ GV + ++ N + A N DR R I ++ I + S++ +N+S S+ D + +K + + LNR+ S Y+T T+TR+F+VDG+ +TTT+ ++V +E++ D+ RK +R ++LAK+E+ + R+L + + + L S+ ++ T K+++ +M+ +++ +K ++E L+ E+ K + ++ +K+E FK++ K+E + K KR+ N + N+N + ++ F+++ + + ++ + + + + E H + ++K +E +QL+ ++ ++F++ + Q+ R E E+ L++ E +L+ I EKK F + +K I K++ L +Q Q L +R +L+ + SK + DA+ R +E EQ E++N L +QET L+E++ RH+N++
Sbjct: 8 FFKRLKSADESGKKNYSSEIERNVNPSDIWEIISELGDGAFGKVYKTHKRGTDLCAALKRVEFDSEDELEDFMVEIDILSNFKHENILSLHEVYIYDSKLWMYLELCGGGALDSIMETLEKGLTEPQIRFISKEVLQGLGFLHEKLIIHRDMKAGNILLTLNNEVKLADFGVSARLADEKQKRLTFIGTPYWMAPEVINCETFKDAPYNWKADIWSFGITLIELAQRRPPYNSINPTRVLLKISKSDPPTLSKPHLWSSKFKTFLARTLQKDPNQRPECKDLLLDPFVSDVTESDRKVIQIL----------LCEVNADIIETVEDLDPNEHIDDIDDNELNTFILPVSTKFSIPVEVDD-SGDDEVGERKDNLASDHEYGENIKELNDSNSGGDSGVSLGRTDSGDHYNGSEKQAVPVNINNGDRIREIIVSPRI--KLTSSNVNENKST---SVNDTLMNASSSSSTTNHHNVNKPTVITSPLNRQNSAYRTRTRTRRFVVDGQVVTTTSKQIVNTNVEDRKLLEDEQIKRKAALRAFRILAKQEAHQTRELNERAQQQMEILESKMGAEFSTLTKTYDHKMEVVSRNYKLQMERLDKDFEIEM----KVIRSETSKEERTFKDRLKSEIDTYDRAMRKAAKRDLHKYDHIQSNHGHMNPSLSSGSINSTISNNSNYCNDNSLVSQRLTMFREKQESRMNSRIYNLHEEYNKRRNLIHADYLNESHALRLNFEEDKWKIEHSYLNMKHQLDRNRQLDLFLIKREQLTGRSELELTELKQAINMERSKLNTIHSIEKKNFMKSLK------AINKRSILTLQRQSRL---------NTIQANEAHKRMNEELELLESKHKTENDALEKSIHFRLQELEQSSVEKRNALIDQETKRLQELDNRHRNEL 880
BLAST of Serine/threonine-protein kinase 10 vs. TrEMBL
Match: A0A3Q3AG73 (Serine/threonine kinase 10 OS=Kryptolebias marmoratus OX=37003 PE=4 SV=1) HSP 1 Score: 416.387 bits (1069), Expect = 1.441e-126 Identity = 262/788 (33.25%), Postives = 436/788 (55.33%), Query Frame = 3
Query: 144 KSYSYLNK-CDPNEVWDVIGEIGDGAFGKVFKAKNKSTDDIAALKQVNLEEEGDLEEYIVEIEILTECKHANVVNLYNAYHFESKLWMALEYCNGGALDSLMITLDKNLNEKAIKYTSKEILSGLIFLHTNGVIHRDMKAGNVLVSKDADVKLADFGVSAKLAADKQKRNTVQGTPYWMAPEVIACQNM-ESYYDCRADIWSFGITLMELAQMRPPYHQMQPTRVLIKIAKADPPTLDRPSLWSSAFISFLKRCLTKKPEDRPHGPDLLSDPFIVSCNDSDKHALKVLXXXXXXXXX-----XXXXXDLDLKDMRHSLLPSQTFDDISEQDDASVGSSDILETPNVIDTISKS-----VFSAEILDNII----SEQIKSEADKVSILGVVVDIMENNPCTNIDDTIAQLDEQNKFDRRRSIRMAMDIVPD-IPISDIKDNESVEKFSIKDEDSDKESNAQAILNRKKSFY--------KTMTKTRKFIVDGEEITTTTTKVVREGLENKNRDQIQDRKMEIRELQLLAKEESREKRQLQFKMLSERDNLASRQKSDELTFEKSHETEMDNLNKLHKSKLENLENQNYHELTNYQKRLLADKAKKENDFK------NKEKTEFGKELDRLPKHQKRENGKKLRDN---NNIIFQEKFKAFQDQLMKDIEEKCESMTATHRLKICELELSLMKEKHQKLSKYNKEKANLEMDQCQSSYQLENQQKKEMFMLGKSQVKHRQEKEIEHLEKNNKKELDELDYIQQNEKKTFPRFIKNTSRTRNIQKKAELEI 2405
K Y ++++ +PN++W+++GE+GDGAFGKV+KA NK T +AA K + + E +LE+YIVEI+IL +C H +V L +A+++E+KLW+ +E+C GGA+D+ M+ LD+ L E IK +++L L++LH +IHRD+KAGN+L++ D D+KLADFGVSAK Q+R+T GTPYWMAPEV+ C+ ++ YD +ADIWS GITL+ELAQ+ PP+H++ P RVL+KIAK++PP L++P WS F FLK+ L + E RP LL PF+ + S++ ++++ E ED D+ D T D + E ++VG+ + +PN +++ + F+A + + K ++ S+ G + N+P N Q + M I P+ I +S + +DS+ A LNR+ F KT+ +TRKF+VDG E++ TT+K++R+ E K+ + R+ E+REL+LL KEE R + L K+ S+++ + R + +K ++TE++ + K HK +E +E + +L KR+ KA++E D+ ++K E +D++P++Q++E K+ + + +EKF A Q + + E ++M A ++ I E+E + K + + ++E +Q +QL QQ K+ + L + + + EKE E +++ N++ ++ L QQ EK P+ +N ++TR K L I
Sbjct: 22 KQYEHVHRDINPNDIWEIVGELGDGAFGKVYKASNKETGILAAAKVIETKCEEELEDYIVEIDILAKCNHQYIVKLLDAFYYENKLWIMIEFCAGGAMDANMLELDRGLTEPQIKVVCRQMLEALVYLHDQKIIHRDLKAGNILLTLDGDIKLADFGVSAKNNKTLQRRDTFIGTPYWMAPEVVMCETTKDAPYDYKADIWSLGITLIELAQIEPPHHELNPMRVLLKIAKSEPPRLEQPHKWSKDFNDFLKKALDRNTETRPSAAQLLEHPFVRTAT-SNRPLMELVAEAKAEVMEEIEDNREEGEDDDIMD---------TIDHLPEDQSSTVGNGEST-SPNSSHSVTPASTPTPSFAATPVPAAHHGPNDTKSKGSLERASMGG---NFGSNSPLLNGRSNDKQHSQAGSLASE-----LMAINPETISVSARVSPHGANHAVVNIQDSN------ACLNRRTLFLSVNQAFSSKTLKRTRKFVVDGVEVSVTTSKIIRDD-EKKDEEMRFLRRQELRELRLLQKEEQRNQADLHAKLESQKEQMQKRFDQEINAKKKQYDTELETMEKNHKQTIEKMEADHNVKLKEETKRI---KAEQERDYHKFLEQLKQKKKEMKHSIDKMPRNQRKETLKQKMSSFQEDKTKQEEKFLAAQKEYLN---ETLKTMIANNKRDIAEMERECLNRKQEFIRAREAASWSMEENQLYEKHQLIKQQMKDQYFLQRHLLLKKHEKETEQMQRYNQRMIEILKSRQQQEKNRLPKIQRNEAKTRMAMFKKSLRI 777
BLAST of Serine/threonine-protein kinase 10 vs. Ensembl Cavefish
Match: slkb (serine/threonine-protein kinase 10 [Source:NCBI gene;Acc:103042643]) HSP 1 Score: 337.806 bits (865), Expect = 7.307e-100 Identity = 149/299 (49.83%), Postives = 214/299 (71.57%), Query Frame = 3
Query: 87 MAFIRDLFKRFKANDPKTKKSYSYLNK-CDPNEVWDVIGEIGDGAFGKVFKAKNKSTDDIAALKQVNLEEEGDLEEYIVEIEILTECKHANVVNLYNAYHFESKLWMALEYCNGGALDSLMITLDKNLNEKAIKYTSKEILSGLIFLHTNGVIHRDMKAGNVLVSKDADVKLADFGVSAKLAADKQKRNTVQGTPYWMAPEVIACQ-NMESYYDCRADIWSFGITLMELAQMRPPYHQMQPTRVLIKIAKADPPTLDRPSLWSSAFISFLKRCLTKKPEDRPHGPDLLSDPFIVSCNDS 977
M+F + K FK K KK Y ++++ +P E+W ++GE+GDGAFGKV+KA+NK + +AA K ++ + E +LE+Y+VEI+IL C H ++V L +A++++SKLW+ +E+C GGA+D++M+ L++ L E I+ ++ L L++LH VIHRD+KAGN+L++ D +VKLADFGVSAK Q+R++ GTPYWMAPEV+ C+ + + YD +ADIWS G+TL+ELAQ+ PP H+M P RVL+KIAKADPPTL +PS WS F FLKRCL K ++R LL PF+ S DS
Sbjct: 1 MSFF-NFRKIFKLGPEKKKKQYEHVHRDVNPEEIWQIVGELGDGAFGKVYKAQNKQSGILAAAKVIDTKTEEELEDYMVEIDILASCDHHHIVKLLDAFYYDSKLWILIEFCAGGAVDAVMLELERPLTEPQIRVVCRQTLEALLYLHEIKVIHRDLKAGNILLTLDGEVKLADFGVSAKNTKTLQRRDSFIGTPYWMAPEVVMCETSKDRPYDYKADIWSLGVTLIELAQIEPPNHEMNPMRVLLKIAKADPPTLMQPSKWSPEFSDFLKRCLDKNVDNRWSAAQLLQHPFVSSVTDS 298 HSP 2 Score: 110.153 bits (274), Expect = 4.417e-24 Identity = 93/341 (27.27%), Postives = 169/341 (49.56%), Query Frame = 3
Query: 1383 DIPISDIKDNESVEKFSIKDEDSDKESNAQAILNRKKSFYKTMTKTRKFIVDGEEITTTTTKVVREGLENKNRDQIQDRKMEIRELQLLAKEESREKRQLQFKMLSERDNLASRQKSDELTFEKSHETEMDNLNKLHKSKLENLENQNYHELTNYQKRLLADKAKKENDFKNKEKTEFGKELDRLPKHQKRENGKKLRDNNNIIFQEKFKAFQDQLMKDIEEKCESMTATHRLKICELELSLMKEKHQKLSKYNKEKANLEMDQCQSSYQLENQQKKEMFMLGKSQVKHRQEKEIEHLEKNNKKELDELDYIQQNEKKTFPRFIKNTSRTRNIQKKAELEI 2405
D IS DN S++ K + AI + K+ KT+ KTRKFIVDG E++ TT+K++ + + KN + R+ E+REL+LL KEE R ++QL K+ +RD + R + + + ++ ++TE++NL + K +E LE ++ L + KR+ A++ K+ + F+N K +E + L K Q+ +++ + + H+ ++ +E + K Q L LE Q +QL QQ K+ + + + Q+ R EKE+E +++ N++ ++E+ Q E+ P+ ++ ++TR K L I
Sbjct: 565 DSGISSAADNSSIDLNLSISSFISKSKESGAIQDTKRQ-KKTLKKTRKFIVDGVEVSVTTSKIITDN-DTKNEEMRFLRRQELRELRLLQKEEQRAQQQLSNKLQQQRDQIYRRFEQETTSKKRQYDTEVENLERQQKQTIERLEQEHTSRLRDEAKRIKAEQDKELSKFQNMLKNRKKEEQEFLQKQQQ----------------------------ELDSALKKIIQQHKHELATVERDCLNHKQQLLRAREAAMWELEERHLQEKHQLHKQQLKDQYFMQRHQLLKRHEKEMEQMQRYNQRLIEEMKTRQTQERTRLPKIQRSDAKTRMAMFKKSLRI 875
BLAST of Serine/threonine-protein kinase 10 vs. Ensembl Cavefish
Match: slkb (serine/threonine-protein kinase 10 [Source:NCBI gene;Acc:103042643]) HSP 1 Score: 337.806 bits (865), Expect = 1.269e-99 Identity = 149/299 (49.83%), Postives = 214/299 (71.57%), Query Frame = 3
Query: 87 MAFIRDLFKRFKANDPKTKKSYSYLNK-CDPNEVWDVIGEIGDGAFGKVFKAKNKSTDDIAALKQVNLEEEGDLEEYIVEIEILTECKHANVVNLYNAYHFESKLWMALEYCNGGALDSLMITLDKNLNEKAIKYTSKEILSGLIFLHTNGVIHRDMKAGNVLVSKDADVKLADFGVSAKLAADKQKRNTVQGTPYWMAPEVIACQ-NMESYYDCRADIWSFGITLMELAQMRPPYHQMQPTRVLIKIAKADPPTLDRPSLWSSAFISFLKRCLTKKPEDRPHGPDLLSDPFIVSCNDS 977
M+F + K FK K KK Y ++++ +P E+W ++GE+GDGAFGKV+KA+NK + +AA K ++ + E +LE+Y+VEI+IL C H ++V L +A++++SKLW+ +E+C GGA+D++M+ L++ L E I+ ++ L L++LH VIHRD+KAGN+L++ D +VKLADFGVSAK Q+R++ GTPYWMAPEV+ C+ + + YD +ADIWS G+TL+ELAQ+ PP H+M P RVL+KIAKADPPTL +PS WS F FLKRCL K ++R LL PF+ S DS
Sbjct: 1 MSFF-NFRKIFKLGPEKKKKQYEHVHRDVNPEEIWQIVGELGDGAFGKVYKAQNKQSGILAAAKVIDTKTEEELEDYMVEIDILASCDHHHIVKLLDAFYYDSKLWILIEFCAGGAVDAVMLELERPLTEPQIRVVCRQTLEALLYLHEIKVIHRDLKAGNILLTLDGEVKLADFGVSAKNTKTLQRRDSFIGTPYWMAPEVVMCETSKDRPYDYKADIWSLGVTLIELAQIEPPNHEMNPMRVLLKIAKADPPTLMQPSKWSPEFSDFLKRCLDKNVDNRWSAAQLLQHPFVSSVTDS 298 HSP 2 Score: 126.331 bits (316), Expect = 5.007e-29 Identity = 97/341 (28.45%), Postives = 179/341 (52.49%), Query Frame = 3
Query: 1383 DIPISDIKDNESVEKFSIKDEDSDKESNAQAILNRKKSFYKTMTKTRKFIVDGEEITTTTTKVVREGLENKNRDQIQDRKMEIRELQLLAKEESREKRQLQFKMLSERDNLASRQKSDELTFEKSHETEMDNLNKLHKSKLENLENQNYHELTNYQKRLLADKAKKENDFKNKEKTEFGKELDRLPKHQKRENGKKLRDNNNIIFQEKFKAFQDQLMKDIEEKCESMTATHRLKICELELSLMKEKHQKLSKYNKEKANLEMDQCQSSYQLENQQKKEMFMLGKSQVKHRQEKEIEHLEKNNKKELDELDYIQQNEKKTFPRFIKNTSRTRNIQKKAELEI 2405
D IS DN S++ K + AI + K+ KT+ KTRKFIVDG E++ TT+K++ + + KN + R+ E+REL+LL KEE R ++QL K+ +RD + R + + + ++ ++TE++NL + K +E LE ++ L + KR+ A++ K+ + F+N K +E P H ++ K+ RD+ E+ + F + ++++ + + H+ ++ +E + K Q L LE Q +QL QQ K+ + + + Q+ R EKE+E +++ N++ ++E+ Q E+ P+ ++ ++TR K L I
Sbjct: 565 DSGISSAADNSSIDLNLSISSFISKSKESGAIQDTKRQ-KKTLKKTRKFIVDGVEVSVTTSKIITDN-DTKNEEMRFLRRQELRELRLLQKEEQRAQQQLSNKLQQQRDQIYRRFEQETTSKKRQYDTEVENLERQQKQTIERLEQEHTSRLRDEAKRIKAEQDKELSKFQNMLKNRKKEETGLSPNHVRKAIVKRFRDDLVQTPHEEEQEFLQKQQQELDSALKKIIQQHKHELATVERDCLNHKQQLLRAREAAMWELEERHLQEKHQLHKQQLKDQYFMQRHQLLKRHEKEMEQMQRYNQRLIEEMKTRQTQERTRLPKIQRSDAKTRMAMFKKSLRI 903
BLAST of Serine/threonine-protein kinase 10 vs. Ensembl Cavefish
Match: slkb (serine/threonine-protein kinase 10 [Source:NCBI gene;Acc:103042643]) HSP 1 Score: 337.035 bits (863), Expect = 1.868e-99 Identity = 149/299 (49.83%), Postives = 214/299 (71.57%), Query Frame = 3
Query: 87 MAFIRDLFKRFKANDPKTKKSYSYLNK-CDPNEVWDVIGEIGDGAFGKVFKAKNKSTDDIAALKQVNLEEEGDLEEYIVEIEILTECKHANVVNLYNAYHFESKLWMALEYCNGGALDSLMITLDKNLNEKAIKYTSKEILSGLIFLHTNGVIHRDMKAGNVLVSKDADVKLADFGVSAKLAADKQKRNTVQGTPYWMAPEVIACQ-NMESYYDCRADIWSFGITLMELAQMRPPYHQMQPTRVLIKIAKADPPTLDRPSLWSSAFISFLKRCLTKKPEDRPHGPDLLSDPFIVSCNDS 977
M+F + K FK K KK Y ++++ +P E+W ++GE+GDGAFGKV+KA+NK + +AA K ++ + E +LE+Y+VEI+IL C H ++V L +A++++SKLW+ +E+C GGA+D++M+ L++ L E I+ ++ L L++LH VIHRD+KAGN+L++ D +VKLADFGVSAK Q+R++ GTPYWMAPEV+ C+ + + YD +ADIWS G+TL+ELAQ+ PP H+M P RVL+KIAKADPPTL +PS WS F FLKRCL K ++R LL PF+ S DS
Sbjct: 1 MSFF-NFRKIFKLGPEKKKKQYEHVHRDVNPEEIWQIVGELGDGAFGKVYKAQNKQSGILAAAKVIDTKTEEELEDYMVEIDILASCDHHHIVKLLDAFYYDSKLWILIEFCAGGAVDAVMLELERPLTEPQIRVVCRQTLEALLYLHEIKVIHRDLKAGNILLTLDGEVKLADFGVSAKNTKTLQRRDSFIGTPYWMAPEVVMCETSKDRPYDYKADIWSLGVTLIELAQIEPPNHEMNPMRVLLKIAKADPPTLMQPSKWSPEFSDFLKRCLDKNVDNRWSAAQLLQHPFVSSVTDS 298 HSP 2 Score: 110.923 bits (276), Expect = 2.517e-24 Identity = 95/349 (27.22%), Postives = 179/349 (51.29%), Query Frame = 3
Query: 1383 DIPISDIKDNESVEKFSIKDEDSDKESNAQAILNRKKSFYKTMTKTRKFIVDGEEITTTTTKVVREGLENKNRDQIQDRKMEIRELQLLAKEESREKRQLQFKMLSERDNLASRQKSDELTFEKSHETEMDNLNKLHKSKLENLENQNYHELTNYQKRLLADKAKKENDFKNKEKTEFGKELDRLPKHQKRENG-----KKLRDNNNIIFQEKFKAFQDQLMK---DIEEKCESMTATHRLKICELELSLMKEKHQKLSKYNKEKANLEMDQCQSSYQLENQQKKEMFMLGKSQVKHRQEKEIEHLEKNNKKELDELDYIQQNEKKTFPRFIKNTSRTRNIQKKAELEI 2405
D IS DN S++ K + AI + K+ KT+ KTRKFIVDG E++ TT+K++ + + KN + R+ E+REL+LL KEE R ++QL K+ +RD + R + + + ++ ++TE++NL + K +E LE ++ L + KR+ A++ K+ + F+N + K++K+E + + ++ +F + Q+ L K +++ + + H+ ++ +E + K Q L LE Q +QL QQ K+ + + + Q+ R EKE+E +++ N++ ++E+ Q E+ P+ ++ ++TR K L I
Sbjct: 565 DSGISSAADNSSIDLNLSISSFISKSKESGAIQDTKRQ-KKTLKKTRKFIVDGVEVSVTTSKIITDN-DTKNEEMRFLRRQELRELRLLQKEEQRAQQQLSNKLQQQRDQIYRRFEQETTSKKRQYDTEVENLERQQKQTIERLEQEHTSRLRDEAKRIKAEQDKELSKFQN------------MLKNRKKEGVAHVMIQSFQLSSCTLFNAPMQDEQEFLQKQQQELDSALKKIIQQHKHELATVERDCLNHKQQLLRAREAAMWELEERHLQEKHQLHKQQLKDQYFMQRHQLLKRHEKEMEQMQRYNQRLIEEMKTRQTQERTRLPKIQRSDAKTRMAMFKKSLRI 899
BLAST of Serine/threonine-protein kinase 10 vs. Ensembl Cavefish
Match: stk10 (serine/threonine-protein kinase 10 [Source:NCBI gene;Acc:103041064]) HSP 1 Score: 336.265 bits (861), Expect = 1.938e-99 Identity = 147/296 (49.66%), Postives = 209/296 (70.61%), Query Frame = 3
Query: 87 MAFIRDLFKRFKANDPKTKKSYSYLNK-CDPNEVWDVIGEIGDGAFGKVFKAKNKSTDDIAALKQVNLEEEGDLEEYIVEIEILTECKHANVVNLYNAYHFESKLWMALEYCNGGALDSLMITLDKNLNEKAIKYTSKEILSGLIFLHTNGVIHRDMKAGNVLVSKDADVKLADFGVSAKLAADKQKRNTVQGTPYWMAPEVIACQNM-ESYYDCRADIWSFGITLMELAQMRPPYHQMQPTRVLIKIAKADPPTLDRPSLWSSAFISFLKRCLTKKPEDRPHGPDLLSDPFIVSC 968
MA I R D K K Y ++++ +P + W+++GE+GDGAFGKV+KA+NK T +AA K + + E +LE+Y+VEI+IL C H +V L +A+++E KLW+ +E+C GGA+D+ M+ LD+ L EK I+ K++L L++LH+ +IHRD+KAGNVL+ D +KLADFGVSAK Q+R++ GTPYWMAPEV+ C+ ++ Y+ +ADIWS GITL+ELAQ+ PP+H++ P RVL+KIAK+DPPTLD+PS WS+ F FL++ L K PE RP LL PF+ S
Sbjct: 1 MASIFGRIFRLPTLDKKRVKQYEHVHRDVNPGDQWEIVGELGDGAFGKVYKAQNKETGVLAAAKVIETKSEEELEDYMVEIDILASCDHHYIVKLLDAFYYEHKLWIMIEFCPGGAVDATMLELDRGLTEKQIQVVCKQMLEALVYLHSMKIIHRDIKAGNVLLMLDGGIKLADFGVSAKNTKTLQRRDSFIGTPYWMAPEVVMCETTKDAPYEYKADIWSLGITLIELAQIEPPHHELNPMRVLLKIAKSDPPTLDQPSKWSADFKDFLRKALDKNPETRPTAAQLLEHPFVTSV 296 HSP 2 Score: 100.908 bits (250), Expect = 3.548e-21 Identity = 82/307 (26.71%), Postives = 165/307 (53.75%), Query Frame = 3
Query: 1503 KTMTKTRKFIVDGEEITTTTTKVVREGLENKNRDQIQDRKMEIRELQLLAKEESREKRQLQFKMLSERDNLASRQKSDELTFEKSHETEMDNLNKLHKSKLENLENQNYHELTNYQKRLLADKAKKENDF---KNKEKTEFGKELDRLPKHQKRENGKKLRDN---NNIIFQEKFKAFQDQLMKDIEEKCESMTATHRLKICELELSLMKEKHQKLSKYNKEKANLEMDQCQSSYQLENQQKKEMFMLGKSQVKHRQEKEIEHLEKNNKKELDELDYIQQNEKKTFPRFIKNTSRTRNIQKKAELEI 2405
+T+ +TRKF+VDG E++ TT K++ + + K+ + R+ E+REL+LL KEE R + L K+ +++D + R + +K ++TE++NL K K +E +E + L KR+ ++ ++ + F + K E E+++LP+ +++E K +N + +E+F+A Q + D+ ++ + ++ +I ++E +++K + + ++E +QL QQ K+ + L + Q+ + EKE EH++ N++ ++ L QQ EK P+ ++ +TR + K L I
Sbjct: 552 RTLKRTRKFLVDGVEVSVTTAKIISDD-DKKDEEMRFLRRQELRELRLLQKEEHRAQAVLNTKLDTQKDQMQRRFDQEMNAKKKYYDTELENLEKHQKQTIEKMELDHAVRLREETKRIRTEQEREYHKFLEMMKRRKKEVKLEVEKLPRRERKETMKARMNNFQLTKVKEEEEFRAAQIHYL-DV--TLNNIISQNKREIADMERQCLEKKQHLIREKEASIWDMEEKNLHERWQLLKQQLKDQYFLQRHQLLKKHEKEQEHMQCYNQRMIELLKARQQQEKNRLPKIQRSEGKTRMVMFKKSLRI 854
BLAST of Serine/threonine-protein kinase 10 vs. Ensembl Cavefish
Match: slkb (serine/threonine-protein kinase 10 [Source:NCBI gene;Acc:103042643]) HSP 1 Score: 337.421 bits (864), Expect = 2.795e-99 Identity = 149/299 (49.83%), Postives = 214/299 (71.57%), Query Frame = 3
Query: 87 MAFIRDLFKRFKANDPKTKKSYSYLNK-CDPNEVWDVIGEIGDGAFGKVFKAKNKSTDDIAALKQVNLEEEGDLEEYIVEIEILTECKHANVVNLYNAYHFESKLWMALEYCNGGALDSLMITLDKNLNEKAIKYTSKEILSGLIFLHTNGVIHRDMKAGNVLVSKDADVKLADFGVSAKLAADKQKRNTVQGTPYWMAPEVIACQ-NMESYYDCRADIWSFGITLMELAQMRPPYHQMQPTRVLIKIAKADPPTLDRPSLWSSAFISFLKRCLTKKPEDRPHGPDLLSDPFIVSCNDS 977
M+F + K FK K KK Y ++++ +P E+W ++GE+GDGAFGKV+KA+NK + +AA K ++ + E +LE+Y+VEI+IL C H ++V L +A++++SKLW+ +E+C GGA+D++M+ L++ L E I+ ++ L L++LH VIHRD+KAGN+L++ D +VKLADFGVSAK Q+R++ GTPYWMAPEV+ C+ + + YD +ADIWS G+TL+ELAQ+ PP H+M P RVL+KIAKADPPTL +PS WS F FLKRCL K ++R LL PF+ S DS
Sbjct: 1 MSFF-NFRKIFKLGPEKKKKQYEHVHRDVNPEEIWQIVGELGDGAFGKVYKAQNKQSGILAAAKVIDTKTEEELEDYMVEIDILASCDHHHIVKLLDAFYYDSKLWILIEFCAGGAVDAVMLELERPLTEPQIRVVCRQTLEALLYLHEIKVIHRDLKAGNILLTLDGEVKLADFGVSAKNTKTLQRRDSFIGTPYWMAPEVVMCETSKDRPYDYKADIWSLGVTLIELAQIEPPNHEMNPMRVLLKIAKADPPTLMQPSKWSPEFSDFLKRCLDKNVDNRWSAAQLLQHPFVSSVTDS 298 HSP 2 Score: 116.316 bits (290), Expect = 5.510e-26 Identity = 99/365 (27.12%), Postives = 181/365 (49.59%), Query Frame = 3
Query: 1383 DIPISDIKDNESVEKFSIKDEDSDKESNAQAILNRKKSFYKTMTKTRKFIVDGEEITTTTTKVVREGLENKNRDQIQDRKMEIRELQLLAKEESREKRQLQFKMLSERDNLASRQKSDELTFEKSHETEMDNLNKLHKSKLENLENQNYHELTNYQKRLLADKAKKENDFKNKEKTEFGKELDRLPKHQKRENGKKLRDN---------------------NNIIFQEKFKAFQDQLMK---DIEEKCESMTATHRLKICELELSLMKEKHQKLSKYNKEKANLEMDQCQSSYQLENQQKKEMFMLGKSQVKHRQEKEIEHLEKNNKKELDELDYIQQNEKKTFPRFIKNTSRTRNIQKKAELEI 2405
D IS DN S++ K + AI + K+ KT+ KTRKFIVDG E++ TT+K++ + + KN + R+ E+REL+LL KEE R ++QL K+ +RD + R + + + ++ ++TE++NL + K +E LE ++ L + KR+ A++ K+ + F+N K +E P H ++ K+ RD+ + +F + Q+ L K +++ + + H+ ++ +E + K Q L LE Q +QL QQ K+ + + + Q+ R EKE+E +++ N++ ++E+ Q E+ P+ ++ ++TR K L I
Sbjct: 565 DSGISSAADNSSIDLNLSISSFISKSKESGAIQDTKRQ-KKTLKKTRKFIVDGVEVSVTTSKIITDN-DTKNEEMRFLRRQELRELRLLQKEEQRAQQQLSNKLQQQRDQIYRRFEQETTSKKRQYDTEVENLERQQKQTIERLEQEHTSRLRDEAKRIKAEQDKELSKFQNMLKNRKKEETGLSPNHVRKAIVKRFRDDLVQTPHEEGVAHVMIQSFQLSSCTLFNAPMQDEQEFLQKQQQELDSALKKIIQQHKHELATVERDCLNHKQQLLRAREAAMWELEERHLQEKHQLHKQQLKDQYFMQRHQLLKRHEKEMEQMQRYNQRLIEEMKTRQTQERTRLPKIQRSDAKTRMAMFKKSLRI 927
BLAST of Serine/threonine-protein kinase 10 vs. Ensembl Sea Lamprey
Match: slka (STE20-like kinase a [Source:ZFIN;Acc:ZDB-GENE-050411-66]) HSP 1 Score: 338.961 bits (868), Expect = 5.183e-100 Identity = 154/301 (51.16%), Postives = 217/301 (72.09%), Query Frame = 3
Query: 87 MAFIRDLFKRFKANDPKTKKSYSYLNK-CDPNEVWDVIGEIGDGAFGKVFKAKNKSTDDIAALKQVNLEEEGDLEEYIVEIEILTECKHANVVNLYNAYHFESKLWMALEYCNGGALDSLMITLDKNLNEKAIKYTSKEILSGLIFLHTNGVIHRDMKAGNVLVSKDADVKLADFGVSAKLAADKQKRNTVQGTPYWMAPEVIACQNM-ESYYDCRADIWSFGITLMELAQMRPPYHQMQPTRVLIKIAKADPPTLDRPSLWSSAFISFLKRCLTKKPEDRPHGPDLLSDPFIVSCNDSDK 983
M++ R +FK ++ + K Y ++ + DP E+W VIGE+GDGAFGKV+KA+NK + +AA K + + E +LE+Y+VEIEIL C H N+V L NA+++E+KLW+ +E+C GGA+D++M+ L++ L E I+ K++L L +LHT+ +IHRD+KAGN+L++ + DVKLADFGVSAK Q+R++ GTPYWMAPEV+ C+ M ++ YD +ADIWS GITL+ELAQM PP H++ P RV++KIAK DPP+L PS WS+ F FLK+CL K PE R + LL FI S DS+K
Sbjct: 1 MSYFRKIFKL--GSERRKPKQYDHVRRDVDPAELWSVIGELGDGAFGKVYKAQNKESGVLAAAKVIETKSEEELEDYMVEIEILALCDHPNIVGLLNAFYYENKLWIFIEFCPGGAVDAIMLELERGLAEPQIRVVCKQMLEALNYLHTHRIIHRDLKAGNILLTFEGDVKLADFGVSAKNTRTLQRRDSFIGTPYWMAPEVVMCETMKDAPYDYKADIWSLGITLIELAQMEPPNHELNPMRVMLKIAKNDPPSLSFPSKWSAEFTDFLKKCLDKNPETRWNALQLLQHSFI-SGVDSNK 298 HSP 2 Score: 109.383 bits (272), Expect = 1.773e-24 Identity = 111/428 (25.93%), Postives = 221/428 (51.64%), Query Frame = 3
Query: 1503 KTMTKTRKFIVDGEEITTTTTKVVREGLENKNRDQIQDRKMEIRELQLLAKEESREKRQLQFKMLSERDNLASRQKSDELTFEKSH-ETEMDNLNKLHKSKLENLENQNYHELTNYQKRLLADKAK---KENDFKNKEKTEFGKELDRLPKHQKRENGKKLRDNNNIIFQEKFKAFQDQLMKDIEEKCESMTATHRLKICELELSLMKEKHQKLSKYNKEKANLEMDQCQSSYQLENQQKKEMFMLGKSQVKHRQEKEIEHLEKNNKKELDELDYIQQNEKKTFPRFIKNTSRTRNIQKKAELEIQLQRNLISSA--DMXXXXXXXXXXXXXXXXXXXXXMNSKLTKKRDAMLAEHFQRRREFEQIHAEQKNELSNQETLFLREIEKRHKNDIXXXXXXXXXXXXXHEQEFKLQEEKMKSFYNTNEKS 2768
KT+ +TRKFIVDG E++ TT K++ E E K+ D R+ E+REL+LL KEE R + L K++ +RD L R+ E++ ++ + + E++ L + K ++E +E ++ L KR+ A++ + K ++ + K E E+++LPK +++ K+ ++ Q + + F + D++ + + H+ ++ ++E + K Q L + LE +QL QQ K+ + L + Q+ R EKE+E +++ +++ L++L Q E+ P+ + ++TR K L I N I S D + + ++ EK ++ ++ + RD + + RE +Q+ E+ + L ET+ L+E++++H ++ K +K E+EF + ++ + F+ T+ +S
Sbjct: 718 KTLKRTRKFIVDGVEVSVTTNKIMNED-EKKDEDLRFLRRQELRELRLLQKEEQRSQALLNGKLMQQRD-LTIRRFETEMSAKRRYFDGEIEKLEREQKQRIEKMEQEHTAHLREEAKRIKAEQDRDLAKFHETQKHRKKEVKSEVEKLPKSVRKDALKRKKEELVQTQQNEEQEFISKQQHDLDGSLKKLIQQHKQEVADVEREFLNSKQQLLREKEASIWELEERHLHEKHQLFKQQLKDQYFLQRHQLLKRHEKELEQMQRYSQRMLEDLKARQAQERARLPKIQRGEAKTRMTMYKKSLRI----NPIGSPEQDRERIKQFAQQEEKRQKAEKQQQAQKHENQMRDLQM-QCDANIRELQQLQNEKCHLLVEHETMKLKELDEQHTQELKTWRDKLRPRKQALEEEFARKRQEQEMFFATSGES 1138
BLAST of Serine/threonine-protein kinase 10 vs. Ensembl Sea Lamprey
Match: myo3a (myosin IIIA [Source:ZFIN;Acc:ZDB-GENE-041026-4]) HSP 1 Score: 223.016 bits (567), Expect = 5.008e-60 Identity = 113/279 (40.50%), Postives = 167/279 (59.86%), Query Frame = 3
Query: 171 DPNEVWDVIGEIGDGAFGKVFKAKNKSTDDIAALKQV----NLEEEG-DLEEYI-VEIEILTEC-KHANVVNLYNAYHFES-----KLWMALEYCNGGALDSLM---ITLDKNLNEKAIKYTSKEILSGLIFLHTNGVIHRDMKAGNVLVSKDADVKLADFGVSAKLAADKQKRNTVQGTPYWMAPEVIAC-QNMESYYDCRADIWSFGITLMELAQMRPPYHQMQPTRVLIKIAKADPPTLDRPSLWSSAFISFLKRCLTKKPEDRPHGPDLLSDPFI 959
DP++ W+++ IG G +GKV+KA ++ AA+K + NLE D++E I E ILT +H N+V + Y+ + +LW+ LE CNGG++ L+ + + ++ I Y + L GL LH++ +IHRD+K N+L++ D ++L DFGVSA+++ + +RNT GTP+WMAPEVIAC Q ++ YD R D+WS GIT +EL PP +++ P R L KI + PPTL +P LW F F+ +CL K E R LL DPFI
Sbjct: 19 DPSDTWELVETIGKGTYGKVYKATSRKDGSKAAVKTLDPVNNLETSNQDIDEEIEAEYSILTSLPEHPNIVRFFGMYYQKDGVNGDQLWIVLELCNGGSVTDLVKGQLKRGERMDVMLIAYILRGALLGLNHLHSHNIIHRDIKGNNILLTTDGGIRLVDFGVSAQVSKTRVERNTAVGTPFWMAPEVIACEQQLDYMYDRRCDVWSMGITAIELGDGDPPLYELHPMRALFKIPRNPPPTLKQPELWPPLFNEFIAQCLVKDFERRATVSQLLEDPFI 297
BLAST of Serine/threonine-protein kinase 10 vs. Ensembl Sea Lamprey
Match: MAP4K3 (mitogen-activated protein kinase kinase kinase kinase 3 [Source:HGNC Symbol;Acc:HGNC:6865]) HSP 1 Score: 218.394 bits (555), Expect = 2.409e-59 Identity = 105/263 (39.92%), Postives = 159/263 (60.46%), Query Frame = 3
Query: 177 NEVWDVIGEIGDGAFGKVFKAKNKSTDDIAALKQVNLEEEGDLEEYIVEIEILTECKHANVVNLYNAYHFESKLWMALEYCNGGALDSLMITLDKNLNEKAIKYTSKEILSGLIFLHTNGVIHRDMKAGNVLVSKDADVKLADFGVSAKLAADKQKRNTVQGTPYWMAPEVIACQNMESYYDCRADIWSFGITLMELAQMRPPYHQMQPTRVLIKIAKA--DPPTLDRPSLWSSAFISFLKRCLTKKPEDRPHGPDLLSDPFI 959
E +++ +G G +G V KA+N T ++ A+K + LE D EI ++ ECKH N+V Y +Y KLW+ +E+C GG+L + + L E+ I Y ++E L GL +LH+ G +HRD+K N+L++ D DVKLADFGVSA++ A KR + GTPYWMAPEV A + + Y+ + D+W+ GIT +ELA+++PP + P R L ++K+ PP L WS F +F+K LTK P+ RP +L+ ++
Sbjct: 11 QEDFELAERLGSGTYGDVHKARNVQTGELVAIKIIKLEPGDDFSVIQQEIVMMKECKHTNIVAYYGSYLRHDKLWICMEHCGGGSLQDIY-HVTGPLTERQIAYVTRETLQGLAYLHSEGKMHRDIKGANILLTDDGDVKLADFGVSAQITATIAKRKSFIGTPYWMAPEVAAVER-KGGYNHQCDVWAVGITAIELAELQPPMFDLHPMRALFLMSKSGFQPPKLRDKQKWSPVFHNFIKMALTKNPKKRPTAEKMLTHSYV 271
BLAST of Serine/threonine-protein kinase 10 vs. Ensembl Sea Lamprey
Match: stk25a (serine/threonine kinase 25a [Source:ZFIN;Acc:ZDB-GENE-041010-92]) HSP 1 Score: 202.986 bits (515), Expect = 2.637e-57 Identity = 120/270 (44.44%), Postives = 164/270 (60.74%), Query Frame = 3
Query: 162 NKC-DPNEVWDVIGEIGDGAFGKVFKAKNKSTDDIAALKQVNLEEEGDLEEYIV-EIEILTECKHANVVNLYNAYHFESKLWMALEYCNGGALDSLMITLDKNLNEKAIKYTSKEILSGLIFLHTNGVIHRDMK--AGNVLVSKDADVKLADFGVSAKLAADKQKRNTVQGTPYWMAPEVIACQNMESYYDCRADIWSFGITLMELAQMRPPYHQMQPTRVLIKIAKADPPTLDRPSLWSSAFISFLKRCLTKKPEDRPHGPDLLSDPFI 959
N C DP E++ IG G+FG+VFK + T ++ A+K ++LEE D E I EI +L++C V + + +Y +KLW+ +EY GG+ +L + L E I +EIL GL +LH+ IHRD+K A NVL+S+ DVKLADFGV+ +L + KRNT GTP+WMAPEVI +S YD +ADIWS GIT +ELA+ PP ++ P RVL I K +PPTL+ +S AF F+ CL K P+ RP +LL FI
Sbjct: 17 NSCADPEELFTKQERIGKGSFGEVFKGIDNRTKEVVAIKIIDLEEAEDEIEDIQQEITVLSQCDSPYVTHYFGSYLKGTKLWIIMEYLGGGS--ALDLIKPGPLEEHQIATILREILKGLDYLHSERKIHRDIKGPAANVLLSEQGDVKLADFGVAGQLTDTQIKRNTFVGTPFWMAPEVIK----QSAYDFKADIWSLGITAIELAKGEPPNSELHPMRVLFLIPKNNPPTLE--GNYSKAFKEFVDSCLNKDPQFRPTAKELLKHKFI 278
BLAST of Serine/threonine-protein kinase 10 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000010511.1 (pep scaffold:Pmarinus_7.0:GL476756:358747:414819:1 gene:ENSPMAG00000009510.1 transcript:ENSPMAT00000010511.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 204.142 bits (518), Expect = 1.125e-54 Identity = 99/246 (40.24%), Postives = 152/246 (61.79%), Query Frame = 3
Query: 231 FKAKNKSTDDIAALKQVNLEEEGDLEEYIVEIEILTECKHANVVNLYNAYHFESKLWMALEYCNGGALDSLMITLDKNLNEKAIKYTSKEILSGLIFLHTNGVIHRDMKAGNVLVSKDADVKLADFGVSAKLAADKQKRNTVQGTPYWMAPEVIACQNMESYYDCRADIWSFGITLMELAQMRPPYHQMQPTRVLIKIAKAD--PPTLDRPSLWSSAFISFLKRCLTKKPEDRPHGPDLLSDPFIV 962
F+A+N + ++A+K + LE D EI ++ EC+H N+V + +Y KLW+ +EYC GG+L + + L+E+ I Y S+E L GL +LH+ +HRD+K N+L++ +VKLADFGVSA++ A KR + GTPYWMAPEV A + + Y+ + D+W+ GIT +ELA+++PP + P R L ++K++ PP L WS F +F+K+ L K P+ RP LL DPF++
Sbjct: 1 FQARNVQSGALSAIKVIKLESGDDFTVIQQEIIMMQECQHINIVAYFGSYLRWDKLWICMEYCGGGSLQDIY-HVTGPLSERQIAYVSRETLKGLAYLHSKCKMHRDIKGANILLTDHGEVKLADFGVSAQITATIAKRMSFIGTPYWMAPEVAAVER-KGGYNQQCDVWAVGITAIELAELQPPMFDLHPMRALFLMSKSNFQPPRLKDKVKWSGIFHNFIKQSLIKNPKKRPTADKLLQDPFVI 244
BLAST of Serine/threonine-protein kinase 10 vs. Ensembl Yeast
Match: STE20 (Cdc42p-activated signal transducing kinase; involved in pheromone response, pseudohyphal/invasive growth, vacuole inheritance, down-regulation of sterol uptake; GBB motif binds Ste4p; member of the PAK (p21-activated kinase) family [Source:SGD;Acc:S000000999]) HSP 1 Score: 201.445 bits (511), Expect = 7.846e-54 Identity = 110/275 (40.00%), Postives = 157/275 (57.09%), Query Frame = 3
Query: 150 YSYLNK-C---DPNEVWDVIGEIGDGAFGKVFKAKNKSTDDIAALKQVNLEEEGDLEEYIVEIEILTECKHANVVNLYNAYHFESKLWMALEYCNGGALDSLMITLDKNLNEKAIKYTSKEILSGLIFLHTNGVIHRDMKAGNVLVSKDADVKLADFGVSAKLAADKQKRNTVQGTPYWMAPEVIACQNMESYYDCRADIWSFGITLMELAQMRPPYHQMQPTRVLIKIAKADPPTLDRPSLWSSAFISFLKRCLTKKPEDRPHGPDLLSDPFIV 962
Y+ LN+ C DP+ + + +IG GA G V+ A T+ A+KQ+NLE++ E I EI ++ KH N+VN ++Y + LW+ +EY GG+L ++ L E I +E LSGL FLH+ GV+HRD+K+ N+L+S + D+KL DFG A++ KR T+ GTPYWMAPEV++ + Y + DIWS GI ++E+ + PPY P R L IA P L P SS+ FL CL +PEDR +LL D +I
Sbjct: 604 YAKLNEICSDGDPSTKYANLVKIGQGASGGVYTAYEIGTNVSVAIKQMNLEKQPKKELIINEILVMKGSKHPNIVNFIDSYVLKGDLWVIMEYMEGGSLTDVVTHCI--LTEGQIGAVCRETLSGLEFLHSKGVLHRDIKSDNILLSMEGDIKLTDFGFCAQINELNLKRTTMVGTPYWMAPEVVSRKE----YGPKVDIWSLGIMIIEMIEGEPPYLNETPLRALYLIATNGTPKLKEPENLSSSLKKFLDWCLCVEPEDRASATELLHDEYIT 872
BLAST of Serine/threonine-protein kinase 10 vs. Ensembl Yeast
Match: SPS1 (Putative protein serine/threonine kinase; localizes to the nucleus and cytoplasm; required for efficient spore packaging, prospore membrane development and closure and localization of enzymes involved in spore wall synthesis; interacts with and required for Ssp1p phosphorylation and turnover; member of the GCKIII subfamily of STE20 kinases; multiply phosphorylated on S/T residues; interacts with 14-3-3 proteins, Bmh1p and Bmh2p; expressed at the end of meiosis [Source:SGD;Acc:S000002931]) HSP 1 Score: 188.348 bits (477), Expect = 7.467e-52 Identity = 106/274 (38.69%), Postives = 154/274 (56.20%), Query Frame = 3
Query: 144 KSYSYLNKCDPNEVWDVIGEIGDGAFGKVFKAKNKSTDDIAALKQVNLEE-EGDLEEYIVEIEILTECKHANVVNLYNAYHFESKLWMALEYCNGGAL-DSLMITLDKNLNEKAIKYTSKEILSGLIFLHTNGVIHRDMKAGNVLVSKDADVKLADFGVSAKLAADKQKRNTVQGTPYWMAPEVIACQNMESYYDCRADIWSFGITLMELAQMRPPYHQMQPTRVLIKIAKADPPTLDRPSLWSSAFISFLKRCLTKKPEDRPHGPDLLSDPFI 959
K S ++ P++++ + IG G FG V+KA ++ T +I A+K VNLE + D+E EI L E K + N + +W+ +EYC GG+ D L + L E+ + + E+ GL +LH IHRD+KA N+L++++ VKL DFGVS + + KR+T GTPYWMAPEV+ C+ Y+ +ADIWS GIT EL + PP + P +V+ + K PP L P +S A F+ CL K P DRP +LLS F+
Sbjct: 4 KEISIRSRTPPSKLYSIQSCIGRGNFGDVYKAVDRVTQEIVAIKVVNLEHSDEDIELLAQEIFFLAELKSPLITNYIATMLEDVSMWIVMEYCGGGSCSDLLKRSYVNGLPEEKVSFIIHEVTLGLKYLHEQRKIHRDIKAANILLNEEGMVKLGDFGVSGHIRST-LKRDTFVGTPYWMAPEVVCCE--VDGYNEKADIWSLGITTYELLKGLPPLSKYDPMKVMTNLPKRKPPKLQGP--FSDAAKDFVAGCLVKTPADRPSAYNLLSFEFV 272
BLAST of Serine/threonine-protein kinase 10 vs. Ensembl Yeast
Match: KIC1 (Protein kinase of the PAK/Ste20 family, required for cell integrity; physically interacts with Cdc31p (centrin), which is a component of the spindle pole body; part of the RAM network that regulates cellular polarity and morphogenesis [Source:SGD;Acc:S000001144]) HSP 1 Score: 191.045 bits (484), Expect = 3.304e-50 Identity = 107/269 (39.78%), Postives = 158/269 (58.74%), Query Frame = 3
Query: 204 IGDGAFGKVFKAKNKSTDDIAALKQVNLEEEGD-LEEYIVEIEILTECKH-ANVVNLYNAYHFESKLWMALEYCNGGALDSLMITLDKNLNEKAIKYTSKEILSGLIFLHTNGVIHRDMKAGNVLVSKDADVKLADFGVSAKLAADKQKRNTVQGTPYWMAPEVIACQNMES-YYDCRADIWSFGITLMELAQMRPPYHQMQPTRVLIKIAKADPPTLDRPSLWSSAFISFLKRCLTKKPEDRPHGPDLLSDPFIVSCNDSDKHALKVL 1001
IG G FG V+K N T + A+K +NL+ + D +E+ EI+ L K +N+ Y +Y ++ LW+ +E+C GG+L SL+ ++EK I +E+L L +H + VIHRD+KA NVL++ + +VKL DFGV+A++ +R T+ GTPYWMAPEVI ME YYD + DIWS GIT E+A PPY ++ R + I K+ PP L+ S +S++ F+ CL + P++R DLL FI + + LK L
Sbjct: 29 IGRGKFGVVYKGYNVKTGRVYAIKVLNLDSDSDEVEDVQREIQFLASLKQISNITRYYGSYLKDTSLWIIMEHCAGGSLRSLL--RPGKIDEKYIGVIMRELLVALKCIHKDNVIHRDIKAANVLITNEGNVKLCDFGVAAQVNQTSLRRQTMAGTPYWMAPEVI----MEGVYYDTKVDIWSLGITTYEIATGNPPYCDVEALRAMQLIIKSKPPRLEDRS-YSTSLKEFIALCLDEDPKERLSADDLLKSKFIRAHKATPTSILKEL 290
BLAST of Serine/threonine-protein kinase 10 vs. Ensembl Yeast
Match: CDC15 (Protein kinase of the Mitotic Exit Network; localized to the spindle pole bodies at late anaphase; promotes mitotic exit by directly switching on the kinase activity of Dbf2p; required for spindle disassembly after meiosis II; relocalizes to the cytoplasm upon DNA replication stress [Source:SGD;Acc:S000000072]) HSP 1 Score: 161.384 bits (407), Expect = 5.818e-41 Identity = 92/254 (36.22%), Postives = 134/254 (52.76%), Query Frame = 3
Query: 204 IGDGAFGKVFKAKNKSTDDIAALKQVNLEEEGDLEEYIVEIEILTECKHANVVNLYNAYHFESKLWMALEYCNGGALDSLMITLDKNLNEKAIKYTSKEILSGLIFLHTNGVIHRDMKAGNVLVSKDADVKLADFGVSAKLAADKQKRNTVQGTPYWMAPEVIACQNMESYYDCRADIWSFGITLMELAQMRPPYHQMQPTRVLIKIAKADPPTLDRPSLWSSAFISFLKRCLTKKPEDRPHGPDLLSDPFIVS 965
IG G++G V+KA NK TD + A+K+V E + +L + + EI +L H N+V + +L++ LEYC G+L L+ L+E K + L GL +LH GVIHRD+KA N+L+S D VKLADFGVS + + T+ GT WMAPE++ + + +DIWS G T++E+ PPYH + + + + T PS +S FL +C K RP LL +I S
Sbjct: 31 IGRGSYGVVYKAINKHTDQVVAIKEVVYENDEELNDIMAEISLLKNLNHNNIVKYHGFIRKSYELYILLEYCANGSLRRLISRSSTGLSENESKTYVTQTLLGLKYLHGEGVIHRDIKAANILLSADNTVKLADFGVSTIVNSSAL---TLAGTLNWMAPEILGNRGASTL----SDIWSLGATVVEMLTKNPPYHNLTDANIYYAV---ENDTYYPPSSFSEPLKDFLSKCFVKNMYKRPTADQLLKHVWINS 274
BLAST of Serine/threonine-protein kinase 10 vs. Ensembl Yeast
Match: SKM1 (Member of the PAK family of serine/threonine protein kinases; similar to Ste20p; involved in down-regulation of sterol uptake; proposed to be a downstream effector of Cdc42p during polarized growth; SKM1 has a paralog, CLA4, that arose from the whole genome duplication [Source:SGD;Acc:S000005473]) HSP 1 Score: 157.532 bits (397), Expect = 2.031e-40 Identity = 91/294 (30.95%), Postives = 146/294 (49.66%), Query Frame = 3
Query: 171 DPNEVWDVIGEIGDGAFGKVFKAK-----------------NKSTDDIAALKQVNLEEEGDLEEYIVEIEILTECKHANVVNLYNAYHFE-SKLWMALEYCNGGALDSLMITLDKN--------LNEKAIKYTSKEILSGLIFLHTNGVIHRDMKAGNVLVSKDADVKLADFGVSAKLAADKQKRNTVQGTPYWMAPEVIACQNMESYYDCRADIWSFGITLMELAQMRPPYHQMQPTRVLIKIAKADPPTLDRPSLWSSAFISFLKRCLTKKPEDRPHGPDLLSDPFI-VSCN 971
+P + ++ + G GA G V+ +K ++ + A+KQ+ L E+ + + E+ ++ + + N+VN AY + +LW+ +EY GG L ++ + ++ LNE + Y KE GL FLH +IHRD+K+ N+L++ VK+ DFG +L + KR T+ GTPYWMAPE++ + YD + D+WS GI L+E+ + PPY P + L IA P L P S FL CL E R LL+ F+ ++C+
Sbjct: 355 NPRPYFQLVEKAGQGASGAVYLSKRIKLPQENDPRFLKSHCHRVVGERVAIKQIRLSEQPKKQLIMNELLVMNDSRQENIVNFLEAYIIDDEELWVIMEYMEGGCLTDILDAVARSNTGEHSSPLNENQMAYIVKETCQGLKFLHNKKIIHRDIKSDNILLNSQGLVKITDFGFCVELTEKRSKRATMVGTPYWMAPEIVN----QKGYDEKVDVWSLGIMLIEMIEGEPPYLNEDPLKALYLIANNGSPKLRHPESVSKQTKQFLDACLQVNVESRASVRKLLTFEFLSMACS 644
BLAST of Serine/threonine-protein kinase 10 vs. Ensembl Nematostella
Match: EDO48741 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RIM4]) HSP 1 Score: 328.946 bits (842), Expect = 8.962e-98 Identity = 143/283 (50.53%), Postives = 201/283 (71.02%), Query Frame = 3
Query: 135 KTKKSYSYLNK-CDPNEVWDVIGEIGDGAFGKVFKAKNKSTDDIAALKQVNLEEEGDLEEYIVEIEILTECKHANVVNLYNAYHFESKLWMALEYCNGGALDSLMITLDKNLNEKAIKYTSKEILSGLIFLHTNGVIHRDMKAGNVLVSKDADVKLADFGVSAKLAADKQKRNTVQGTPYWMAPEVIACQNM-ESYYDCRADIWSFGITLMELAQMRPPYHQMQPTRVLIKIAKADPPTLDRPSLWSSAFISFLKRCLTKKPEDRPHGPDLLSDPFIVSCNDS 977
K KK +SY+ K DPN W+++GE+GDG+FGKV+KA++K+ ++A K + + +E +LE+++VEI+IL+ECKH N+V L+ + + KLWM LE+C+GGALD LM+ L++ LNE I+ ++++ GL FLH + VIHRD+KAGN+L++ D +VK+ADFGVSAK QKR+T GTPYWMAPEV+ + + YD +ADIWS GITL+ELAQM PP H M P RVL KI K+DPPT D P+ WS+ FL C+ K P+ R +++ PFI D+
Sbjct: 4 KKKKEFSYIIKDVDPNSNWELVGELGDGSFGKVYKAQHKTESSLSAAKIIIVNDENELEDFMVEIDILSECKHKNLVGLFETFLHDGKLWMMLEFCSGGALDDLMLELERGLNEPEIRAVTRQLFEGLQFLHNHKVIHRDLKAGNLLLASDGNVKMADFGVSAKNKKTLQKRSTFIGTPYWMAPEVVVTETYKDDPYDYKADIWSAGITLIELAQMVPPNHNMHPMRVLFKIPKSDPPTFDNPNKWSNDLNDFLASCVVKNPDMRASATEMIKHPFIADFTDN 286 HSP 2 Score: 106.686 bits (265), Expect = 1.878e-23 Identity = 90/314 (28.66%), Postives = 172/314 (54.78%), Query Frame = 3
Query: 1500 YKTMTKTRKFI-VDGEEITTTTTKVVR-EGLENKN---RDQIQDRKMEIRELQLLAKEESREKRQLQFKMLSERDNLASRQKSDELTFEKSHETEMDNLNKLHKSKLENLENQNYHELTNYQKRLLADKAKKENDFK---NKEKTEFGKELDRLPKHQKRENGKKLRDNNNIIFQEKFKAFQDQLMKDIEEKCESMTATHRLKICELELSLMKEKHQKLSKYNKEKANLEMDQCQSSYQLENQQKKEMFMLGKSQVKHRQEKEIEHLEKNNKKELDELDYIQQNEKKTFPRFIKN--TSRTRNIQKKAELEIQL 2411
+KT+ +TRKF DG+ +T TT++VV G + KN + Q+Q RK+ +REL++L + E ++ +L ++ + + R + + L E+ +E E+DNL++ K +E LE +L +++ D+ K+ FK +E+ KE+D+LP++Q+++ KK ++ ++ Q+ FQ + E+ + M HR K+ E+E+ ++ KH++ + EK +E +QL Q KE F L +SQ+ +R KE+E + K + +++ + E+K P+ +N S+T+N +K ++ Q+
Sbjct: 504 FKTLKRTRKFANQDGQIVTETTSRVVDVSGEDYKNALIKAQMQ-RKVNLRELKVLQRLEQKQGIELMTRIRRQWETQEQRFEQELLELERKYEIELDNLSRNQKRDIEKLELTQNADLRTSSRKMRQDQEKELKKFKENLKEEQKRSKKEVDKLPRNQRKDAWKKKKEELDLSHQQAEHEFQAMQQVEFEKFYKQMIDLHRQKMFEMEMHFLESKHERKRAHESEKWEIEFRHLNERHQLAKTQLKETFFLQRSQMLNRHLKEVEQHQHLTKLQEEDMKRRHEIERKRLPKIQRNEIKSKTQNYRKSLRVDKQM 816
BLAST of Serine/threonine-protein kinase 10 vs. Ensembl Nematostella
Match: EDO42845 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S0A9]) HSP 1 Score: 244.202 bits (622), Expect = 3.666e-73 Identity = 118/262 (45.04%), Postives = 161/262 (61.45%), Query Frame = 3
Query: 174 PNEVWDVIGEIGDGAFGKVFKAKNKSTDDIAALKQVNLEEEGDLEEYIVEIEILTECKHANVVNLYNAYHFESKLWMALEYCNGGALDSLMITLDKNLNEKAIKYTSKEILSGLIFLHTNGVIHRDMKAGNVLVSKDADVKLADFGVSAKLAADKQKRNTVQGTPYWMAPEVIACQNMESYYDCRADIWSFGITLMELAQMRPPYHQMQPTRVLIKIAKADPPTLDRPSLWSSAFISFLKRCLTKKPEDRPHGPDLLSDPFI 959
P EV+DV+ ++G+G++G VFKA +K + + A+KQV ++ DL+E I EI ++ +C VV Y +Y + LW+ +EYC G++ LM +K L E+ IK K L GL +LH IHRD+KAGN+L++ + KLADFGV+ +L KRNTV GTP+WMAPEVI E YDC ADIWS GIT ME+A+ +PPY + P R + I PPT P WS F F+ +CL K PE+R +LL FI
Sbjct: 20 PEEVFDVLEKLGEGSYGSVFKAMHKESGQVVAIKQVPVDT--DLQEIIKEISMMQQCDSPYVVKYYGSYFKNTDLWIVMEYCGAGSVSDLMKIRNKTLTEEEIKCVLKYTLKGLEYLHLRRKIHRDIKAGNILLNSEGHAKLADFGVAGQLTDTMAKRNTVIGTPFWMAPEVI----QEVGYDCLADIWSLGITAMEMAEGKPPYADIHPMRAIFMIPTKPPPTFRDPGQWSEDFKDFVSKCLVKNPEERATATELLQHSFI 275
BLAST of Serine/threonine-protein kinase 10 vs. Ensembl Nematostella
Match: EDO49047 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RHW1]) HSP 1 Score: 223.402 bits (568), Expect = 7.674e-66 Identity = 108/283 (38.16%), Postives = 169/283 (59.72%), Query Frame = 3
Query: 159 LNKCDPNEVWDVIGEIGDGAFGKVFKAKNKSTDDIAALKQVNLEEEGDLEEYIVEIEILTECKHANVVNLYNAYHFESKLWMALEYCNGGALDSLMITLDKNLNEKAIKYTSKEILSGLIFLHTNGVIHRDMKAGNVLVSKDADVKLADFGVSAKLAADKQKRNTVQGTPYWMAPEVIACQNMESYYDCRADIWSFGITLMELAQMRPPYHQMQPTRVLIKIAKAD--PPTLDRPSLWSSAFISFLKRCLTKKPEDRPHGPDLLSDPFIVSCNDSDKHALKVL 1001
+++ +P++V+D+I ++G G +G VFKA+ +T D+AA+K V +E D E EI ++ +C+H N++N AY KLW+ +EYC GG++ + + +E I + + E L GL +LH ++HRD+K N+L++ + +VKLADFG+SA++ +KR + GTPYWMAPE+ A + YD + DIW+ GIT +E+A+++PP + P R L I K PPTL WS+ F+K L K P+ RP +L+ PF C K L+ L
Sbjct: 9 ISRGNPDKVFDLIEKVGGGTYGDVFKARVIATGDLAAVKVVKVEPGDDFELIQQEIAMMQQCRHNNIINYIGAYMRRDKLWIGMEYCGGGSIQDVY-CVTGPCSETQISFVTVETLKGLAYLHEKSLMHRDIKGANILLTTNGEVKLADFGISARITETMKKRKSFIGTPYWMAPEMAAVERTGG-YDLKCDIWAVGITAIEMAELQPPMFDLHPMRALYIIGKKSFIPPTLKEKDKWSNEMHHFIKVALIKNPKKRPSADKMLTHPF--CCRHLTKAVLQDL 287
BLAST of Serine/threonine-protein kinase 10 vs. Ensembl Nematostella
Match: EDO31934 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SWI4]) HSP 1 Score: 207.223 bits (526), Expect = 6.354e-59 Identity = 118/266 (44.36%), Postives = 160/266 (60.15%), Query Frame = 3
Query: 165 KCDPNEVWDVIGEIGDGAFGKVFKAKNKSTDDIAALKQVNLEEEGDLEEYIV-EIEILTECKHANVVNLYNAYHFESKLWMALEYCNGGALDSLMITLDKNLNEKAIKYTSKEILSGLIFLHTNGVIHRDMKAGNVLVSKDADVKLADFGVSAKLAADKQKRNTVQGTPYWMAPEVIACQNMESYYDCRADIWSFGITLMELAQMRPPYHQMQPTRVLIKIAKADPPTLDRPSLWSSAFISFLKRCLTKKPEDRPHGPDLLSDPFI 959
K DP +++ + IG G+FG+VFK + T+++ A+K ++LEE D E I EI +L++C V + +Y +KLW+ +EY GG+ LM N+ E I +E+L GL +LHT +HRD+KA NVL+S+ DVKLADFGV+ +L KRNT GTP+WMAPEVI +S YD +ADIWS GIT +ELA+ PP + P RVL I K +PP L +S AF F+ CL K P DRP +LL FI
Sbjct: 4 KADPEKLFSKLERIGKGSFGEVFKGIDNRTNEVVAIKIIDLEEAEDEIEDIQQEITVLSQCDSLYVTKYHGSYLKGTKLWIIMEYLGGGSALDLMKA--GNIEEFYIATILREVLKGLDYLHTEKKLHRDIKAANVLMSETGDVKLADFGVAGQLTDTLNKRNTFVGTPFWMAPEVIK----QSAYDSKADIWSLGITAIELAKGEPPNSDLHPMRVLFLIPKNNPPELT--GNFSKAFKEFVSLCLNKDPNDRPTAKELLKHRFI 261
BLAST of Serine/threonine-protein kinase 10 vs. Ensembl Nematostella
Match: EDO40961 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S5T6]) HSP 1 Score: 202.986 bits (515), Expect = 1.872e-58 Identity = 113/280 (40.36%), Postives = 170/280 (60.71%), Query Frame = 3
Query: 171 DPNEVWDVIGEIGDGAFGKVFKAKNKSTDDIAALKQVNLEEEGDLEEYIVEIEILTE-CKHANVVNLYNAYHFES------KLWMALEYCNGGALDSLMITL-DKNLNEKAIKYTSKEILSGLIFLHTNGVIHRDMKAGNVLVSKDADVKLADFGVSAKLAADKQKRNTVQGTPYWMAPEVIAC-QNMESYYDCRADIWSFGITLMELAQMRPPYHQMQPTRVLIKIAKADPPTLDRPSLWSSAFISFLKRCLTKKPEDRPHGPDLLSDPFIVSCNDSDK 983
DP ++D++ +G+G +G+V K ++K T + A+K +++ E+ + EE +EI +L + H N+ Y A+ +S +LW+ +E+C G++ L+ T +K L E+ I Y +E+L+G+ LH N VIHRD+K NVL+++ A+VKL DFGVSA+L +RNT GTPYWMAPEVIAC + ++ YD R D+WS GIT +E+A+ +PP M P R L I ++DPP L WS F F+ CL K + RP LL FI S++
Sbjct: 15 DPAGIFDLVEVVGNGTYGQVHKGRHKRTGQLTAIKIMDVTED-EEEEIKLEINVLRKFSNHRNIATYYGAFIKKSLQGQDDQLWLVMEFCGAGSVTDLVKTARNKALKEEWISYICREVLNGVSHLHMNHVIHRDIKGQNVLLTESAEVKLVDFGVSAQLDRTIGRRNTFIGTPYWMAPEVIACDEQPDATYDNRCDMWSIGITAIEMAESQPPLCDMHPMRALFLIPRSDPPKLKSKKSWSKRFHHFVNTCLIKDYQHRPTADQLLQHEFIKDVRSSER 293
BLAST of Serine/threonine-protein kinase 10 vs. Ensembl Medaka
Match: slkb (serine/threonine-protein kinase 10 [Source:NCBI gene;Acc:101170491]) HSP 1 Score: 345.895 bits (886), Expect = 3.308e-103 Identity = 155/299 (51.84%), Postives = 213/299 (71.24%), Query Frame = 3
Query: 87 MAFIRDLFKRFKANDPKTKKSYSYLNKCD-PNEVWDVIGEIGDGAFGKVFKAKNKSTDDIAALKQVNLEEEGDLEEYIVEIEILTECKHANVVNLYNAYHFESKLWMALEYCNGGALDSLMITLDKNLNEKAIKYTSKEILSGLIFLHTNGVIHRDMKAGNVLVSKDADVKLADFGVSAKLAADKQKRNTVQGTPYWMAPEVIACQ-NMESYYDCRADIWSFGITLMELAQMRPPYHQMQPTRVLIKIAKADPPTLDRPSLWSSAFISFLKRCLTKKPEDRPHGPDLLSDPFIVSCNDS 977
M+F + K FK K KK Y ++ + + P EVW++IGE+GDGAFGKVFKA+NK T +AA K ++ + E +LE+Y+VEI+IL C H N+V L +A+++E KLW+ +E+C GGA+D++M+ L++ L E I+ ++ L L +LH N +IHRD+KAGN+L+S D DVKLADFGVSA+ Q+R++ GTPYWMAPEV+ C+ + + YD +ADIWS G+TL+ELAQ+ PP H+M P RVL+KIAK+DPPTL +PS WS F FLKRCL K E+R LL PF+ S DS
Sbjct: 1 MSFF-NFRKIFKLGAEKKKKQYEHVRRDENPEEVWEIIGELGDGAFGKVFKAQNKQTGILAAAKVIDTKTEEELEDYMVEIDILASCDHQNIVKLLDAFYYEGKLWILIEFCAGGAVDAVMLELERPLTEPQIRAVCRQTLEALTYLHENKIIHRDLKAGNILLSLDGDVKLADFGVSARNTKTLQRRDSFIGTPYWMAPEVVMCETSKDRPYDYKADIWSLGVTLIELAQIEPPNHEMNPMRVLLKIAKSDPPTLMQPSRWSPEFSDFLKRCLDKNVENRWTTAQLLQHPFVSSVTDS 298 HSP 2 Score: 92.0485 bits (227), Expect = 1.671e-18 Identity = 76/293 (25.94%), Postives = 146/293 (49.83%), Query Frame = 3
Query: 1527 FIVDGEEITTTTTKVVREGLENKNRDQIQDRKMEIRELQLLAKEESREKRQLQFKMLSERDNLASRQKSDELTFEKSHETEMDNLNKLHKSKLENLENQNYHELTNYQKRLLADKAKKENDFKNKEKTEFGKELDRLPKHQKRENGKKLRDNNNIIFQEKFKAFQDQLMKDIEEKCESMTATHRLKICELELSLMKEKHQKLSKYNKEKANLEMDQCQSSYQLENQQKKEMFMLGKSQVKHRQEKEIEHLEKNNKKELDELDYIQQNEKKTFPRFIKNTSRTRNIQKKAELEI 2405
FIVDG E++ TT+K++ + + KN + R+ E+REL+LL KEE R ++QL K+ +++ + R + + + ++ ++ E++NL + K +E LE ++ L + KR+ AD+ K+ + ++N K +E + L K Q+ D++ + + H+ ++ +E + K Q L LE Q +QL QQ K+ + + + Q+ R EKE+E +++ N++ ++EL Q E+ P+ ++ ++TR K L I
Sbjct: 564 FIVDGVEVSVTTSKIITDN-DTKNEEMRFLRRQELRELRLLQKEEQRAQQQLSNKLQQQKEQIFRRFEQETTSKKRQYDQEVENLERQQKQTIERLEQEHTARLRDEAKRIKADQDKELSKYQNMLKNRKKEEQEFLQKQQQ----------------------------DLDAALKKIIQQHKHELATVERDCLNHKQQLLRAREAAMWELEERHLQEKHQLFKQQLKDQYFMQRHQLLKRHEKEMEQMQRYNQRLIEELKNKQTQERTRLPKIQRSEAKTRMAMFKKSLRI 827
BLAST of Serine/threonine-protein kinase 10 vs. Ensembl Medaka
Match: slkb (serine/threonine-protein kinase 10 [Source:NCBI gene;Acc:101170491]) HSP 1 Score: 345.895 bits (886), Expect = 5.282e-103 Identity = 155/299 (51.84%), Postives = 213/299 (71.24%), Query Frame = 3
Query: 87 MAFIRDLFKRFKANDPKTKKSYSYLNKCD-PNEVWDVIGEIGDGAFGKVFKAKNKSTDDIAALKQVNLEEEGDLEEYIVEIEILTECKHANVVNLYNAYHFESKLWMALEYCNGGALDSLMITLDKNLNEKAIKYTSKEILSGLIFLHTNGVIHRDMKAGNVLVSKDADVKLADFGVSAKLAADKQKRNTVQGTPYWMAPEVIACQ-NMESYYDCRADIWSFGITLMELAQMRPPYHQMQPTRVLIKIAKADPPTLDRPSLWSSAFISFLKRCLTKKPEDRPHGPDLLSDPFIVSCNDS 977
M+F + K FK K KK Y ++ + + P EVW++IGE+GDGAFGKVFKA+NK T +AA K ++ + E +LE+Y+VEI+IL C H N+V L +A+++E KLW+ +E+C GGA+D++M+ L++ L E I+ ++ L L +LH N +IHRD+KAGN+L+S D DVKLADFGVSA+ Q+R++ GTPYWMAPEV+ C+ + + YD +ADIWS G+TL+ELAQ+ PP H+M P RVL+KIAK+DPPTL +PS WS F FLKRCL K E+R LL PF+ S DS
Sbjct: 1 MSFF-NFRKIFKLGAEKKKKQYEHVRRDENPEEVWEIIGELGDGAFGKVFKAQNKQTGILAAAKVIDTKTEEELEDYMVEIDILASCDHQNIVKLLDAFYYEGKLWILIEFCAGGAVDAVMLELERPLTEPQIRAVCRQTLEALTYLHENKIIHRDLKAGNILLSLDGDVKLADFGVSARNTKTLQRRDSFIGTPYWMAPEVVMCETSKDRPYDYKADIWSLGVTLIELAQIEPPNHEMNPMRVLLKIAKSDPPTLMQPSRWSPEFSDFLKRCLDKNVENRWTTAQLLQHPFVSSVTDS 298 HSP 2 Score: 93.2041 bits (230), Expect = 7.546e-19 Identity = 78/301 (25.91%), Postives = 157/301 (52.16%), Query Frame = 3
Query: 1527 FIVDGEEITTTTTKVVREGLENKNRDQIQDRKMEIRELQLLAKEESREKRQLQFKMLSERDNLASRQKSDELTFEKSHETEMDNLNKLHKSKLENLENQNYHELTNYQKRLLADKAKKENDFKNKEKTEFGKELDRLPKHQKRENG-----KKLRDNNNIIFQEKFKAFQDQLMK---DIEEKCESMTATHRLKICELELSLMKEKHQKLSKYNKEKANLEMDQCQSSYQLENQQKKEMFMLGKSQVKHRQEKEIEHLEKNNKKELDELDYIQQNEKKTFPRFIKNTSRTRNIQKKAELEI 2405
FIVDG E++ TT+K++ + + KN + R+ E+REL+LL KEE R ++QL K+ +++ + R + + + ++ ++ E++NL + K +E LE ++ L + KR+ AD+ K+ + ++N + K++K+E + +++ + + F+ Q+ L K D++ + + H+ ++ +E + K Q L LE Q +QL QQ K+ + + + Q+ R EKE+E +++ N++ ++EL Q E+ P+ ++ ++TR K L I
Sbjct: 564 FIVDGVEVSVTTSKIITDN-DTKNEEMRFLRRQELRELRLLQKEEQRAQQQLSNKLQQQKEQIFRRFEQETTSKKRQYDQEVENLERQQKQTIERLEQEHTARLRDEAKRIKADQDKELSKYQN------------MLKNRKKEGVLHVMIQSFELSSSTLCRSPFQDEQEFLQKQQQDLDAALKKIIQQHKHELATVERDCLNHKQQLLRAREAAMWELEERHLQEKHQLFKQQLKDQYFMQRHQLLKRHEKEMEQMQRYNQRLIEELKNKQTQERTRLPKIQRSEAKTRMAMFKKSLRI 851
BLAST of Serine/threonine-protein kinase 10 vs. Ensembl Medaka
Match: stk10 (serine/threonine-protein kinase 10 [Source:NCBI gene;Acc:101167671]) HSP 1 Score: 332.798 bits (852), Expect = 3.081e-98 Identity = 144/297 (48.48%), Postives = 213/297 (71.72%), Query Frame = 3
Query: 87 MAFIRDLFKRFKANDPKTKKSYSYLNK-CDPNEVWDVIGEIGDGAFGKVFKAKNKSTDDIAALKQVNLEEEGDLEEYIVEIEILTECKHANVVNLYNAYHFESKLWMALEYCNGGALDSLMITLDKNLNEKAIKYTSKEILSGLIFLHTNGVIHRDMKAGNVLVSKDADVKLADFGVSAKLAADKQKRNTVQGTPYWMAPEVIACQNM-ESYYDCRADIWSFGITLMELAQMRPPYHQMQPTRVLIKIAKADPPTLDRPSLWSSAFISFLKRCLTKKPEDRPHGPDLLSDPFIVSCN 971
MA R K F+ + K K Y ++++ +PN++W+++GE+GDGAFGKV+KAKNK T +AA K + + E +LE+Y+VEI+IL +C H +V L +A+++E+KLW+ +E+C GGA+D+ M+ LD+ L E I+ +++L L++LH+ +IHRD+KAGN+L++ D +KLADFGVSAK Q+R++ GTPYWMAPEV+ C+ M ++ YD +ADIWS GITL+ELAQ+ PP+H++ P RV++KIAK++PPTLD P WS+ F +FL+ L K E RP LL PF+ S
Sbjct: 1 MALSR-FSKMFRIDTKKKGKQYEHVHRDVNPNDLWEIVGELGDGAFGKVYKAKNKETGVLAAAKVIETKSEEELEDYMVEIDILAKCDHEYIVKLLDAFYYENKLWIMIEFCPGGAMDANMLELDRGLTEPQIRVVCRQMLEALVYLHSMKIIHRDLKAGNILLTLDGTIKLADFGVSAKNTKTLQRRDSFIGTPYWMAPEVVMCETMKDTPYDYKADIWSLGITLIELAQIEPPHHELNPMRVMLKIAKSEPPTLDEPYKWSNDFNNFLRTALDKNQETRPTAAQLLEHPFVKSVT 296 HSP 2 Score: 97.0561 bits (240), Expect = 4.825e-20 Identity = 91/343 (26.53%), Postives = 177/343 (51.60%), Query Frame = 3
Query: 1410 NESVEKFSIKDEDSDKESNAQAILNRKKSFY-KTMTKTRKFIVDGEEITTTTTKVVREGLENKNRDQIQDRKMEIRELQLLAKEESREKRQLQFKMLSERDNLASRQKSDELTFEKSHETEMDNLNKLHKSKLENLENQNYHELTNYQKRLLADKAKKENDFKNK---EKTEFGKELDRLPKHQKRENGKKLRDNNNII-------FQEKFKAFQDQLMKDIEEKCESMTATHRLKICELELSLMKEKHQKLSKYNKEKANLEMDQCQSSYQLENQQKKEMFMLGKSQVKHRQEKEIEHLEKNNKKELDELDYIQQNEKKTFPRFIKNTSRTRNIQKKAELEI 2405
N S+ + SI E+ D + + ++F KT+ +TRKF+VDG E++ TT+KV+RE E K + R+ E+REL+LL KEE R +L K+ ++++++ R + T ++ +TE++N+ K HK +E +E+ + +L KR+ +++ ++ F+ + +K E + + LP++ ++E+ ++ + F K K F D+ +K+I ++ +I E+E + +K + + + +E +QL QQ K+ + L + Q+ + E E H++ N++ ++ L QQ EK P+ + ++TR K L I
Sbjct: 524 NGSISRDSIASENMDMSAQRELKPLSSRNFSNKTLKRTRKFVVDGVEVSVTTSKVIRED-EKKEEEMRFLRRQELRELRLLQKEEQRALAELNVKLEAQKEHVQKRYDQEMNTKKRFFDTELENMEKHHKQTIEKMESDHNVKLKEETKRIKSEQEREYRKFQEQMKHKKKEVKQSVLTLPRNTRKESLRQSMSEFQVKKKTEEEEFLAKQKEFLDKTVKEI-------INNNKREIAEMERECLNKKQELIREGEGTIWGMEEKFHHERHQLLKQQLKDQYFLQRHQLLKKHEMEQNHMQCYNQRMIEILKARQQQEKSRLPKIQRGEAKTRMAMFKKSLRI 858
BLAST of Serine/threonine-protein kinase 10 vs. Ensembl Medaka
Match: slka (STE20 like kinase [Source:NCBI gene;Acc:101171519]) HSP 1 Score: 335.109 bits (858), Expect = 4.160e-98 Identity = 147/299 (49.16%), Postives = 213/299 (71.24%), Query Frame = 3
Query: 87 MAFIRDLFKRFKANDPKTKKSYSYLNK-CDPNEVWDVIGEIGDGAFGKVFKAKNKSTDDIAALKQVNLEEEGDLEEYIVEIEILTECKHANVVNLYNAYHFESKLWMALEYCNGGALDSLMITLDKNLNEKAIKYTSKEILSGLIFLHTNGVIHRDMKAGNVLVSKDADVKLADFGVSAKLAADKQKRNTVQGTPYWMAPEVIACQ-NMESYYDCRADIWSFGITLMELAQMRPPYHQMQPTRVLIKIAKADPPTLDRPSLWSSAFISFLKRCLTKKPEDRPHGPDLLSDPFIVSCNDS 977
M+F + K FK K KK Y ++++ +P E+W++IGE+GDGAFGKVFKA+NK +AA K ++ + E +LE+Y+VEI+IL C H ++V L +A++FE+KLW+ +E+C GGA+D++M+ L++ L E I+ K+ L L++LH +IHRD+KAGN+L+S D +VKLADFGVSAK Q+R + GTPYWMAPEV+ C+ + + YD +ADIWS G+TL+E+AQ+ PP H+M P RVL+KIAK++PPTL +PS WS F FL++ L K ++R LL PF+ S +DS
Sbjct: 1 MSFF-NFRKIFKLGPDKKKKQYEHVHRDANPEEIWEIIGELGDGAFGKVFKAQNKQNGTLAAAKVIDTKSEDELEDYMVEIDILASCDHPHIVKLLDAFYFEAKLWILIEFCAGGAVDAIMLELERPLTEPQIRVVCKQTLEALVYLHERKIIHRDLKAGNILLSLDGEVKLADFGVSAKNTKTLQRRVSFIGTPYWMAPEVVMCETSKDRPYDYKADIWSLGVTLIEMAQVEPPNHEMNPMRVLLKIAKSEPPTLMQPSRWSPEFSDFLRKALDKNVDNRWSPLQLLQHPFVSSVSDS 298 HSP 2 Score: 110.923 bits (276), Expect = 3.294e-24 Identity = 119/422 (28.20%), Postives = 207/422 (49.05%), Query Frame = 3
Query: 1479 LNRKKSFYKTMTKTRKFIVDGEEITTTTTKVVREGLENKNRDQIQDRKMEIRELQLLAKEESREKRQLQFKMLSERDNLASRQKSDELTFEKSHETEMDNLNKLHKSKLENLENQNYHELTNYQKRLLADKAKKENDFKNKEKTEFGKELDRLPKHQKRENGKKLRDNNNIIFQEKFKAFQDQLMKDIEEKCESMTATHRLKICELELSLMKEKHQKLSKYNKEKANLEMDQCQSSYQLENQQKKEMFMLGKSQVKHRQEKEIEHLEKNNKKELDELDYIQQNEKKTFPRFIKNTSRTRNIQKKAELEIQLQRNLISSADMXXXXXXXXXXXXXXXXXXXXXMNSKLTKKRDAMLAEHFQRRREFEQIHAEQKNELSNQETLFLREIEKRHKNDIXXXXXXXXXXXXXHEQEF--KLQEEKM 2738
L K KT+ KTRKF+VDG E++ TT+K+V + + KN + R+ E+REL+LL KEE R ++QL K+L +R+ + R + ++ ++ E++NL K K +E LE + + L + KR+ D+ K+ + F+N K +E + L K Q+ +G L K I++ H+L+I +E + K Q + LE Q +QL QQ K+ + + + Q+ R EKE+E +++ N++ ++EL Q EK P+ ++ ++TR K L I + + + + EK ++ L + + RD L + RE +Q+ E+ + L ET L+E+++ H +I E +K +K E+EF KLQE+++
Sbjct: 718 LQESKRQKKTLKKTRKFMVDGVEVSVTTSKIVTDN-DTKNEEMRFLRRQELRELRLLQKEEQRAQQQLSNKLLQQREQIYRRFDQETTVKKRQYDQEVENLEKKQKQTIERLEQDHTNRLRDEAKRIKTDQEKELSKFQNMMKNRKKEEQEFLQKQQQELDGA--------------------LKKIIQQ--------HKLEIATIERDCLNHKQQLMRAREAAMWELEERHLQEKHQLLKQQLKDQYFMQRHQLLKRHEKEMEQMQRYNQRLIEELKNKQAQEKARLPKIQRSDAKTRMAMYKKSLRITATAAITPEQERERIKLFAVQEEKRQKNERLHQQQKHENQMRDLQL-QCDSNVRELQQLQNEKCHLLIEHETQKLKELDEEHSQEIKEWREKLRPRKKALEEEFTRKLQEQEV 1109
BLAST of Serine/threonine-protein kinase 10 vs. Ensembl Medaka
Match: stk10 (serine/threonine-protein kinase 10 [Source:NCBI gene;Acc:101167671]) HSP 1 Score: 333.183 bits (853), Expect = 4.211e-98 Identity = 144/297 (48.48%), Postives = 213/297 (71.72%), Query Frame = 3
Query: 87 MAFIRDLFKRFKANDPKTKKSYSYLNK-CDPNEVWDVIGEIGDGAFGKVFKAKNKSTDDIAALKQVNLEEEGDLEEYIVEIEILTECKHANVVNLYNAYHFESKLWMALEYCNGGALDSLMITLDKNLNEKAIKYTSKEILSGLIFLHTNGVIHRDMKAGNVLVSKDADVKLADFGVSAKLAADKQKRNTVQGTPYWMAPEVIACQNM-ESYYDCRADIWSFGITLMELAQMRPPYHQMQPTRVLIKIAKADPPTLDRPSLWSSAFISFLKRCLTKKPEDRPHGPDLLSDPFIVSCN 971
MA R K F+ + K K Y ++++ +PN++W+++GE+GDGAFGKV+KAKNK T +AA K + + E +LE+Y+VEI+IL +C H +V L +A+++E+KLW+ +E+C GGA+D+ M+ LD+ L E I+ +++L L++LH+ +IHRD+KAGN+L++ D +KLADFGVSAK Q+R++ GTPYWMAPEV+ C+ M ++ YD +ADIWS GITL+ELAQ+ PP+H++ P RV++KIAK++PPTLD P WS+ F +FL+ L K E RP LL PF+ S
Sbjct: 1 MALSR-FSKMFRIDTKKKGKQYEHVHRDVNPNDLWEIVGELGDGAFGKVYKAKNKETGVLAAAKVIETKSEEELEDYMVEIDILAKCDHEYIVKLLDAFYYENKLWIMIEFCPGGAMDANMLELDRGLTEPQIRVVCRQMLEALVYLHSMKIIHRDLKAGNILLTLDGTIKLADFGVSAKNTKTLQRRDSFIGTPYWMAPEVVMCETMKDTPYDYKADIWSLGITLIELAQIEPPHHELNPMRVMLKIAKSEPPTLDEPYKWSNDFNNFLRTALDKNQETRPTAAQLLEHPFVKSVT 296 HSP 2 Score: 95.5153 bits (236), Expect = 1.529e-19 Identity = 84/311 (27.01%), Postives = 163/311 (52.41%), Query Frame = 3
Query: 1503 KTMTKTRKFIVDGEEITTTTTKVVREGLENKNRDQIQDRKMEIRELQLLAKEESREKRQLQFKMLSERDNLASRQKSDELTFEKSHETEMDNLNKLHKSKLENLENQNYHELTNYQKRLLADKAKKENDFKNK---EKTEFGKELDRLPKHQKRENGKKLRDNNNII-------FQEKFKAFQDQLMKDIEEKCESMTATHRLKICELELSLMKEKHQKLSKYNKEKANLEMDQCQSSYQLENQQKKEMFMLGKSQVKHRQEKEIEHLEKNNKKELDELDYIQQNEKKTFPRFIKNTSRTRNIQKKAELEI 2405
KT+ +TRKF+VDG E++ TT+KV+RE E K + R+ E+REL+LL KEE R +L K+ ++++++ R + T ++ +TE++N+ K HK +E +E+ + +L KR+ +++ ++ F+ + +K E + + LP++ ++E+ ++ + F K K F D+ +K+I ++ +I E+E + +K + + + +E +QL QQ K+ + L + Q+ + E E H++ N++ ++ L QQ EK P+ + ++TR K L I
Sbjct: 582 KTLKRTRKFVVDGVEVSVTTSKVIRED-EKKEEEMRFLRRQELRELRLLQKEEQRALAELNVKLEAQKEHVQKRYDQEMNTKKRFFDTELENMEKHHKQTIEKMESDHNVKLKEETKRIKSEQEREYRKFQEQMKHKKKEVKQSVLTLPRNTRKESLRQSMSEFQVKKKTEEEEFLAKQKEFLDKTVKEI-------INNNKREIAEMERECLNKKQELIREGEGTIWGMEEKFHHERHQLLKQQLKDQYFLQRHQLLKKHEMEQNHMQCYNQRMIEILKARQQQEKSRLPKIQRGEAKTRMAMFKKSLRI 884
BLAST of Serine/threonine-protein kinase 10 vs. Planmine SMEST
Match: SMESG000064983.1 (SMESG000064983.1) HSP 1 Score: 1769.98 bits (4583), Expect = 0.000e+0 Identity = 913/916 (99.67%), Postives = 915/916 (99.89%), Query Frame = 3
Query: 87 MAFIRDLFKRFKANDPKTKKSYSYLNKCDPNEVWDVIGEIGDGAFGKVFKAKNKSTDDIAALKQVNLEEEGDLEEYIVEIEILTECKHANVVNLYNAYHFESKLWMALEYCNGGALDSLMITLDKNLNEKAIKYTSKEILSGLIFLHTNGVIHRDMKAGNVLVSKDADVKLADFGVSAKLAADKQKRNTVQGTPYWMAPEVIACQNMESYYDCRADIWSFGITLMELAQMRPPYHQMQPTRVLIKIAKADPPTLDRPSLWSSAFISFLKRCLTKKPEDRPHGPDLLSDPFIVSCNDSDKHALKVLXXXXXXXXXXXXXXDLDLKDMRHSLLPSQTFDDISEQDDASVGSSDILETPNVIDTISKSVFSAEILDNIISEQIKSEADKVSILGVVVDIMENNPCTNIDDTIAQLDEQNKFDRRRSIRMAMDIVPDIPISDIKDNESVEKFSIKDEDSDKESNAQAILNRKKSFYKTMTKTRKFIVDGEEITTTTTKVVREGLENKNRDQIQDRKMEIRELQLLAKEESREKRQLQFKMLSERDNLASRQKSDELTFEKSHETEMDNLNKLHKSKLENLENQNYHELTNYQKRLLADKAKKENDFKNKEKTEFGKELDRLPKHQKRENGKKLRDNNNIIFQEKFKAFQDQLMKDIEEKCESMTATHRLKICELELSLMKEKHQKLSKYNKEKANLEMDQCQSSYQLENQQKKEMFMLGKSQVKHRQEKEIEHLEKNNKKELDELDYIQQNEKKTFPRFIKNTSRTRNIQKKAELEIQLQRNLISSADMXXXXXXXXXXXXXXXXXXXXXMNSKLTKKRDAMLAEHFQRRREFEQIHAEQKNELSNQETLFLREIEKRHKNDIXXXXXXXXXXXXXHEQEFKLQEEKMKSFYNTNEKSYGNITPYSSKIVNENKVVEALC 2834
MAFIRDLFKRFKANDPKTKKSYSYLNKCDPNEVWDVIGEIGDGAFGKVFKAKNKSTDDIAALKQVNLEEEGDLEEYIVEIEILTECKHANVVNLYNAYHFESKLWMALEYCNGGALDSLMITLDKNLNEKAIKYTSKEILSGLIFLHTNGVIHRDMKAGNVLVSKDADVKLADFGVSAKLAADKQKRNTVQGTPYWMAPEVIACQNMESYYDCRADIWSFGITLMELAQMRPPYHQMQPTRVLIKIAKADPPTLDRPSLWSSAFISFLKRCLTKKPEDRPHGPDLLSDPFIVSCNDSDKHALKVLIYEANAENIEEVVEDLDLKDMRHSLLPSQTFDDISEQDDASVGSSDILETPNVID ISKSVFSAEILDNIISEQIKSEADKVSILGVVVDIMENNPCTNIDDTIAQLDEQNKFDRRRSIRMAMDIVPDIPISDIKDNESVEKFSIKDEDSDKESNAQAILNRKKSFYKTMTKTRKF+VDGEEITTTTTKVVREGLENKNRDQIQDRKMEIRELQLLAKEESREKRQLQFKMLSERDNLASRQKSDELTFEKSHETEMDNLNKLHKSKLENLENQNYHELTNYQKRLLADKAKKENDFKNKEKTEFGKELDRLPKHQKRENGKKLRDNNNIIFQEKFKAFQDQLMKDIEEKCESMTATHRLKICELELSLMKEKHQKLSKYNKEKANLEMDQCQSSYQLENQQKKEMFMLGKSQVKHRQEKEIEHLEKNNKKELDELDYIQQNEKKTFPRFIKNTSRTRNIQKKAELEIQLQRNLISSADMKAKLKEFEERE+EREKSDLKRMNSKLTKKRDAMLAEHFQRRREFEQIHAEQKNELSNQETLFLREIEKRHKNDILELSKKAESKKLLHEQEFKLQEEKMKSFYNTNEKSYGNITPYSSKIVNENKVVEALC
Sbjct: 1 MAFIRDLFKRFKANDPKTKKSYSYLNKCDPNEVWDVIGEIGDGAFGKVFKAKNKSTDDIAALKQVNLEEEGDLEEYIVEIEILTECKHANVVNLYNAYHFESKLWMALEYCNGGALDSLMITLDKNLNEKAIKYTSKEILSGLIFLHTNGVIHRDMKAGNVLVSKDADVKLADFGVSAKLAADKQKRNTVQGTPYWMAPEVIACQNMESYYDCRADIWSFGITLMELAQMRPPYHQMQPTRVLIKIAKADPPTLDRPSLWSSAFISFLKRCLTKKPEDRPHGPDLLSDPFIVSCNDSDKHALKVLIYEANAENIEEVVEDLDLKDMRHSLLPSQTFDDISEQDDASVGSSDILETPNVIDNISKSVFSAEILDNIISEQIKSEADKVSILGVVVDIMENNPCTNIDDTIAQLDEQNKFDRRRSIRMAMDIVPDIPISDIKDNESVEKFSIKDEDSDKESNAQAILNRKKSFYKTMTKTRKFVVDGEEITTTTTKVVREGLENKNRDQIQDRKMEIRELQLLAKEESREKRQLQFKMLSERDNLASRQKSDELTFEKSHETEMDNLNKLHKSKLENLENQNYHELTNYQKRLLADKAKKENDFKNKEKTEFGKELDRLPKHQKRENGKKLRDNNNIIFQEKFKAFQDQLMKDIEEKCESMTATHRLKICELELSLMKEKHQKLSKYNKEKANLEMDQCQSSYQLENQQKKEMFMLGKSQVKHRQEKEIEHLEKNNKKELDELDYIQQNEKKTFPRFIKNTSRTRNIQKKAELEIQLQRNLISSADMKAKLKEFEEREREREKSDLKRMNSKLTKKRDAMLAEHFQRRREFEQIHAEQKNELSNQETLFLREIEKRHKNDILELSKKAESKKLLHEQEFKLQEEKMKSFYNTNEKSYGNITPYSSKIVNENKVVEALC 916
BLAST of Serine/threonine-protein kinase 10 vs. Planmine SMEST
Match: SMESG000018196.1 (SMESG000018196.1) HSP 1 Score: 229.95 bits (585), Expect = 5.885e-66 Identity = 112/271 (41.33%), Postives = 166/271 (61.25%), Query Frame = 3
Query: 171 DPNEVWDVIGEIGDGAFGKVFKAKNKSTDDIAALKQVNLEEEGDLEEYIVEIEILTECKHANVVNLYNAYHFESKLWMALEYCNGGALDSLMITLDKNLNEKAIKYTSKEILSGLIFLHTNGVIHRDMKAGNVLVSKDADVKLADFGVSAKLAADKQKRNTVQGTPYWMAPEVIACQNMESYYDCRADIWSFGITLMELAQMRPPYHQMQPTRVLIKIAKADPPTLDRPSLWSSAFISFLKRCLTKKPEDRPHGPDLLSD-PFIVSCNDSD 980
+P+EV+ + ++G G++G V+KAK+K A K V ++ E L + + EI I+ +CK +V Y +++ LW+ +EYC G++ +M +K NE+ I + L GL ++H IHRD+KAGN+L+++D + KLADFGV+ +L+ KRNTV GTPYWMAPEVI E Y ADIWS GIT +E+A +PPY + P R L I PPTL PS+WS +F++F+ +CL K P+ RP LL + FI++ + D
Sbjct: 12 EPSEVFQIESKLGKGSYGSVYKAKHKKNGFTVAAKLVPVDSE--LSDIVKEISIMQQCKSDYIVQYYGSFYDSHDLWIVMEYCGAGSVSDIMRLRNKTCNEEEIAIILQGSLKGLEYIHQLKKIHRDIKAGNILLTEDGNAKLADFGVAGQLSDTLAKRNTVIGTPYWMAPEVI----QEIGYHYSADIWSLGITAIEMADGKPPYADIHPMRALFMIPSQPPPTLLNPSIWSPSFVNFITQCLVKNPDQRPSASQLLLNCEFIINASSPD 276
BLAST of Serine/threonine-protein kinase 10 vs. Planmine SMEST
Match: SMESG000041176.1 (SMESG000041176.1) HSP 1 Score: 226.483 bits (576), Expect = 1.365e-61 Identity = 103/271 (38.01%), Postives = 165/271 (60.89%), Query Frame = 3
Query: 156 YLNKCDPNEVWDVIGEIGDGAFGKVFKAKNKSTDDIAALKQVNLEEEGDLEEYIVEIEILTECKHANVVNLYNAYHFESKLWMALEYCNGGALDSLMITLDKNLNEKAIKYTSKEILSGLIFLHTNGVIHRDMKAGNVLVSKDADVKLADFGVSAKLAADKQKRNTVQGTPYWMAPEVIACQNMESYYDCRADIWSFGITLMELAQMRPPYHQMQPTRVLIKIAKA--DPPTLDRPSLWSSAFISFLKRCLTKKPEDRPHGPDLLSDPFIV 962
++N +P + + +I EIG G +G V+KA + + + A+K + ++ + D+ EI L ECKH N+V + +Y SKLW+ +EYC G ++ + + L + + E I + ++E L GL ++H G IHRD+K N+L++ DVK+ADFG++AKL++ KR T+ GTPYWMAPEV A N YD R D+W+ GIT +E A+++PP + P + L +A+ PP L + +WS+ F SFL+ L K + RP+ +L+ F+
Sbjct: 12 FVNHSNPKDEYKLISEIGSGTYGDVYKAMHVKSQNYVAIKIMKIDLKDDVTAICQEIHTLRECKHDNIVQFFGSYLQASKLWICMEYCGGQSMQDIYLNLRRPIIEDCIAFITRETLKGLDYMHKRGRIHRDIKGANILLTDLGDVKIADFGIAAKLSSTVAKRTTLIGTPYWMAPEVAAVNNRTGGYDERCDVWAVGITAIEYAELQPPLFDLHPMKALQILAQRTYTPPKLQKKEIWSAKFHSFLRFALAKNEKKRPYCETMLTHDFVT 282
BLAST of Serine/threonine-protein kinase 10 vs. Planmine SMEST
Match: SMESG000041176.1 (SMESG000041176.1) HSP 1 Score: 226.483 bits (576), Expect = 1.428e-61 Identity = 103/271 (38.01%), Postives = 165/271 (60.89%), Query Frame = 3
Query: 156 YLNKCDPNEVWDVIGEIGDGAFGKVFKAKNKSTDDIAALKQVNLEEEGDLEEYIVEIEILTECKHANVVNLYNAYHFESKLWMALEYCNGGALDSLMITLDKNLNEKAIKYTSKEILSGLIFLHTNGVIHRDMKAGNVLVSKDADVKLADFGVSAKLAADKQKRNTVQGTPYWMAPEVIACQNMESYYDCRADIWSFGITLMELAQMRPPYHQMQPTRVLIKIAKA--DPPTLDRPSLWSSAFISFLKRCLTKKPEDRPHGPDLLSDPFIV 962
++N +P + + +I EIG G +G V+KA + + + A+K + ++ + D+ EI L ECKH N+V + +Y SKLW+ +EYC G ++ + + L + + E I + ++E L GL ++H G IHRD+K N+L++ DVK+ADFG++AKL++ KR T+ GTPYWMAPEV A N YD R D+W+ GIT +E A+++PP + P + L +A+ PP L + +WS+ F SFL+ L K + RP+ +L+ F+
Sbjct: 12 FVNHSNPKDEYKLISEIGSGTYGDVYKAMHVKSQNYVAIKIMKIDLKDDVTAICQEIHTLRECKHDNIVQFFGSYLQASKLWICMEYCGGQSMQDIYLNLRRPIIEDCIAFITRETLKGLDYMHKRGRIHRDIKGANILLTDLGDVKIADFGIAAKLSSTVAKRTTLIGTPYWMAPEVAAVNNRTGGYDERCDVWAVGITAIEYAELQPPLFDLHPMKALQILAQRTYTPPKLQKKEIWSAKFHSFLRFALAKNEKKRPYCETMLTHDFVT 282
BLAST of Serine/threonine-protein kinase 10 vs. Planmine SMEST
Match: SMESG000041176.1 (SMESG000041176.1) HSP 1 Score: 226.098 bits (575), Expect = 1.551e-61 Identity = 103/271 (38.01%), Postives = 165/271 (60.89%), Query Frame = 3
Query: 156 YLNKCDPNEVWDVIGEIGDGAFGKVFKAKNKSTDDIAALKQVNLEEEGDLEEYIVEIEILTECKHANVVNLYNAYHFESKLWMALEYCNGGALDSLMITLDKNLNEKAIKYTSKEILSGLIFLHTNGVIHRDMKAGNVLVSKDADVKLADFGVSAKLAADKQKRNTVQGTPYWMAPEVIACQNMESYYDCRADIWSFGITLMELAQMRPPYHQMQPTRVLIKIAKA--DPPTLDRPSLWSSAFISFLKRCLTKKPEDRPHGPDLLSDPFIV 962
++N +P + + +I EIG G +G V+KA + + + A+K + ++ + D+ EI L ECKH N+V + +Y SKLW+ +EYC G ++ + + L + + E I + ++E L GL ++H G IHRD+K N+L++ DVK+ADFG++AKL++ KR T+ GTPYWMAPEV A N YD R D+W+ GIT +E A+++PP + P + L +A+ PP L + +WS+ F SFL+ L K + RP+ +L+ F+
Sbjct: 12 FVNHSNPKDEYKLISEIGSGTYGDVYKAMHVKSQNYVAIKIMKIDLKDDVTAICQEIHTLRECKHDNIVQFFGSYLQASKLWICMEYCGGQSMQDIYLNLRRPIIEDCIAFITRETLKGLDYMHKRGRIHRDIKGANILLTDLGDVKIADFGIAAKLSSTVAKRTTLIGTPYWMAPEVAAVNNRTGGYDERCDVWAVGITAIEYAELQPPLFDLHPMKALQILAQRTYTPPKLQKKEIWSAKFHSFLRFALAKNEKKRPYCETMLTHDFVT 282 The following BLAST results are available for this feature:
BLAST of Serine/threonine-protein kinase 10 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99) Total hits: 5
BLAST of Serine/threonine-protein kinase 10 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99) Total hits: 5
BLAST of Serine/threonine-protein kinase 10 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99) Total hits: 5
BLAST of Serine/threonine-protein kinase 10 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99) Total hits: 5
BLAST of Serine/threonine-protein kinase 10 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99) Total hits: 5
BLAST of Serine/threonine-protein kinase 10 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99) Total hits: 5
BLAST of Serine/threonine-protein kinase 10 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt) Total hits: 5
BLAST of Serine/threonine-protein kinase 10 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL) Total hits: 5
BLAST of Serine/threonine-protein kinase 10 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99) Total hits: 5
BLAST of Serine/threonine-protein kinase 10 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99) Total hits: 5
BLAST of Serine/threonine-protein kinase 10 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46) Total hits: 5
BLAST of Serine/threonine-protein kinase 10 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46) Total hits: 5
BLAST of Serine/threonine-protein kinase 10 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99) Total hits: 5
BLAST of Serine/threonine-protein kinase 10 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST) Total hits: 5
Analyses
This transcript is derived from or has results from the following analyses Sequences
The following sequences are available for this feature:
transcript sequence >SMED30013563 ID=SMED30013563|Name=Serine/threonine-protein kinase 10|organism=Schmidtea mediterranea sexual|type=transcript|length=2971bpback to top protein sequence of SMED30013563-orf-1 >SMED30013563-orf-1 ID=SMED30013563-orf-1|Name=SMED30013563-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=917bp MAFIRDLFKRFKANDPKTKKSYSYLNKCDPNEVWDVIGEIGDGAFGKVFKback to top Annotated Terms
The following terms have been associated with this transcript:
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
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