Hepatocyte growth factor receptor

Overview


Name	Hepatocyte growth factor receptor
Smed ID	SMED30013495
Length (bp)	2633

Neoblast Clusters

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Overview

Single cell RNA-seq of pluripotent neoblasts and its early progenies

We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)

Explore this single cell expression dataset with our NB Cluster Shiny App

Neoblast Population

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.

Expression of Hepatocyte growth factor receptor (SMED30013495) t-SNE clustered cells

Violin plots show distribution of expression levels for Hepatocyte growth factor receptor (SMED30013495) in cells (dots) of each of the 12 neoblast clusters.

Sub-lethal Irradiated Surviving X1 and X2 Cell Population

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of Hepatocyte growth factor receptor (SMED30013495) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for Hepatocyte growth factor receptor (SMED30013495) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
Sort Descending | Sort Ascending | Only Non-Zero Values | Tile/Chart | Reset

Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

Anatomical Expression

PAGE et. al., 2020

SMED30013495

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE

PAGE Curations: 2

Expressed In	Reference Transcript	Gene Models	Published Transcript	Transcriptome	Publication	Specimen	Lifecycle	Evidence
X1 cell	SMED30013495	SMESG000037119.1	SmedASXL_015400	SmedAsxl_ww_GCZZ01	PMID:26114597 Zhu et al., 2015
neoblast	SMED30013495	SMESG000037119.1	dd_Smed_v4_12706_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018

Note: Hover over icons to view figure legend

Homology

[Close]

BLAST of Hepatocyte growth factor receptor vs. Ensembl Human
Match: MET (MET proto-oncogene, receptor tyrosine kinase [Source:HGNC Symbol;Acc:HGNC:7029])

HSP 1 Score: 115.546 bits (288), Expect = 1.653e-25
Identity = 83/268 (30.97%), Postives = 136/268 (50.75%), Query Frame = 3

Query: 1803 IGRGNFSTVFKAKYSRSKDNAIPVAAKWLNDKND-KTLNKIKTE-LFPSTFPHKNVLKSYGYCILKDQTYLI--SELAFQDLLRYLQS-NQLPNDRTCINFCLQVCQGMKFLSDDRKFIHRDLAARNILVFKDKDENVTLKISDFGLTIKLMNKNYYN-SNSQGNFF---WLPDDEFKTGKFTVKTDIYSYGVVMWEIFSGGKD----------VVKMRKSHRTLPKEFDDIKILDGAYNLMKGCWSV-GDLQPNDFNSLIHLLKALL 2546
            IGRG+F  V+      +    I  A K LN   D   +++  TE +    F H NVL   G C+  + + L+    +   DL  ++++    P  +  I F LQV +GMK+L+  +KF+HRDLAARN ++    DE  T+K++DFGL   + +K YY+  N  G      W+  +  +T KFT K+D++S+GV++WE+ + G             V + +  R L  E+      D  Y +M  CW    +++P+ F+ L+  + A+ 
Sbjct: 1084 IGRGHFGCVYHGTLLDNDGKKIHCAVKSLNRITDIGEVSQFLTEGIIMKDFSHPNVLSLLGICLRSEGSPLVVLPYMKHGDLRNFIRNETHNPTVKDLIGFGLQVAKGMKYLAS-KKFVHRDLAARNCML----DEKFTVKVADFGLARDMYDKEYYSVHNKTGAKLPVKWMALESLQTQKFTTKSDVWSFGVLLWELMTRGAPPYPDVNTFDITVYLLQGRRLLQPEY----CPDPLYEVMLKCWHPKAEMRPS-FSELVSRISAIF 1341

[Close]

BLAST of Hepatocyte growth factor receptor vs. Ensembl Human
Match: MET (MET proto-oncogene, receptor tyrosine kinase [Source:HGNC Symbol;Acc:HGNC:7029])

HSP 1 Score: 115.546 bits (288), Expect = 1.798e-25
Identity = 83/268 (30.97%), Postives = 136/268 (50.75%), Query Frame = 3

Query: 1803 IGRGNFSTVFKAKYSRSKDNAIPVAAKWLNDKND-KTLNKIKTE-LFPSTFPHKNVLKSYGYCILKDQTYLI--SELAFQDLLRYLQS-NQLPNDRTCINFCLQVCQGMKFLSDDRKFIHRDLAARNILVFKDKDENVTLKISDFGLTIKLMNKNYYN-SNSQGNFF---WLPDDEFKTGKFTVKTDIYSYGVVMWEIFSGGKD----------VVKMRKSHRTLPKEFDDIKILDGAYNLMKGCWSV-GDLQPNDFNSLIHLLKALL 2546
            IGRG+F  V+      +    I  A K LN   D   +++  TE +    F H NVL   G C+  + + L+    +   DL  ++++    P  +  I F LQV +GMK+L+  +KF+HRDLAARN ++    DE  T+K++DFGL   + +K YY+  N  G      W+  +  +T KFT K+D++S+GV++WE+ + G             V + +  R L  E+      D  Y +M  CW    +++P+ F+ L+  + A+ 
Sbjct: 1102 IGRGHFGCVYHGTLLDNDGKKIHCAVKSLNRITDIGEVSQFLTEGIIMKDFSHPNVLSLLGICLRSEGSPLVVLPYMKHGDLRNFIRNETHNPTVKDLIGFGLQVAKGMKYLAS-KKFVHRDLAARNCML----DEKFTVKVADFGLARDMYDKEYYSVHNKTGAKLPVKWMALESLQTQKFTTKSDVWSFGVLLWELMTRGAPPYPDVNTFDITVYLLQGRRLLQPEY----CPDPLYEVMLKCWHPKAEMRPS-FSELVSRISAIF 1359

[Close]

BLAST of Hepatocyte growth factor receptor vs. Ensembl Human
Match: MST1R (macrophage stimulating 1 receptor [Source:HGNC Symbol;Acc:HGNC:7381])

HSP 1 Score: 113.62 bits (283), Expect = 7.621e-25
Identity = 74/246 (30.08%), Postives = 131/246 (53.25%), Query Frame = 3

Query: 1803 IGRGNFSTVFKAKYSRSKDNAIPVAAKWLNDKNDKTLNK--IKTELFPSTFPHKNVLKSYGYCILKD--QTYLISELAFQDLLRYLQSNQL-PNDRTCINFCLQVCQGMKFLSDDRKFIHRDLAARNILVFKDKDENVTLKISDFGLTIKLMNKNYY----NSNSQGNFFWLPDDEFKTGKFTVKTDIYSYGVVMWEIFSGGK---------DVVKMRKSHRTLPK-EFDDIKILDGAYNLMKGCW 2483
            IG+G+F  V+  +Y     N I  A K L+   +    +  ++  L      H NVL   G  +  +     L+  +   DLL++++S Q  P  +  I+F LQV +GM++L++ +KF+HRDLAARN ++    DE+ T+K++DFGL   ++++ YY    + +++    W+  +  +T +FT K+D++S+GV++WE+ + G          D+       R LP+ E+      D  Y +M+ CW
Sbjct: 1088 IGKGHFGVVYHGEYIDQAQNRIQCAIKSLSRITEMQQVEAFLREGLLMRGLNHPNVLALIGIMLPPEGLPHVLLPYMCHGDLLQFIRSPQRNPTVKDLISFGLQVARGMEYLAE-QKFVHRDLAARNCML----DESFTVKVADFGLARDILDREYYSVQQHRHARLPVKWMALESLQTYRFTTKSDVWSFGVLLWELLTRGAPPYRHIDPFDLTHFLAQGRRLPQPEY----CPDSLYQVMQQCW 1324

[Close]

BLAST of Hepatocyte growth factor receptor vs. Ensembl Human
Match: MST1R (macrophage stimulating 1 receptor [Source:HGNC Symbol;Acc:HGNC:7381])

HSP 1 Score: 113.62 bits (283), Expect = 7.672e-25
Identity = 74/246 (30.08%), Postives = 131/246 (53.25%), Query Frame = 3

Query: 1803 IGRGNFSTVFKAKYSRSKDNAIPVAAKWLNDKNDKTLNK--IKTELFPSTFPHKNVLKSYGYCILKD--QTYLISELAFQDLLRYLQSNQL-PNDRTCINFCLQVCQGMKFLSDDRKFIHRDLAARNILVFKDKDENVTLKISDFGLTIKLMNKNYY----NSNSQGNFFWLPDDEFKTGKFTVKTDIYSYGVVMWEIFSGGK---------DVVKMRKSHRTLPK-EFDDIKILDGAYNLMKGCW 2483
            IG+G+F  V+  +Y     N I  A K L+   +    +  ++  L      H NVL   G  +  +     L+  +   DLL++++S Q  P  +  I+F LQV +GM++L++ +KF+HRDLAARN ++    DE+ T+K++DFGL   ++++ YY    + +++    W+  +  +T +FT K+D++S+GV++WE+ + G          D+       R LP+ E+      D  Y +M+ CW
Sbjct: 1039 IGKGHFGVVYHGEYIDQAQNRIQCAIKSLSRITEMQQVEAFLREGLLMRGLNHPNVLALIGIMLPPEGLPHVLLPYMCHGDLLQFIRSPQRNPTVKDLISFGLQVARGMEYLAE-QKFVHRDLAARNCML----DESFTVKVADFGLARDILDREYYSVQQHRHARLPVKWMALESLQTYRFTTKSDVWSFGVLLWELLTRGAPPYRHIDPFDLTHFLAQGRRLPQPEY----CPDSLYQVMQQCW 1275

[Close]

BLAST of Hepatocyte growth factor receptor vs. Ensembl Human
Match: MST1R (macrophage stimulating 1 receptor [Source:HGNC Symbol;Acc:HGNC:7381])

HSP 1 Score: 113.235 bits (282), Expect = 8.512e-25
Identity = 74/246 (30.08%), Postives = 131/246 (53.25%), Query Frame = 3

Query: 1803 IGRGNFSTVFKAKYSRSKDNAIPVAAKWLNDKNDKTLNK--IKTELFPSTFPHKNVLKSYGYCILKD--QTYLISELAFQDLLRYLQSNQL-PNDRTCINFCLQVCQGMKFLSDDRKFIHRDLAARNILVFKDKDENVTLKISDFGLTIKLMNKNYY----NSNSQGNFFWLPDDEFKTGKFTVKTDIYSYGVVMWEIFSGGK---------DVVKMRKSHRTLPK-EFDDIKILDGAYNLMKGCW 2483
            IG+G+F  V+  +Y     N I  A K L+   +    +  ++  L      H NVL   G  +  +     L+  +   DLL++++S Q  P  +  I+F LQV +GM++L++ +KF+HRDLAARN ++    DE+ T+K++DFGL   ++++ YY    + +++    W+  +  +T +FT K+D++S+GV++WE+ + G          D+       R LP+ E+      D  Y +M+ CW
Sbjct:  982 IGKGHFGVVYHGEYIDQAQNRIQCAIKSLSRITEMQQVEAFLREGLLMRGLNHPNVLALIGIMLPPEGLPHVLLPYMCHGDLLQFIRSPQRNPTVKDLISFGLQVARGMEYLAE-QKFVHRDLAARNCML----DESFTVKVADFGLARDILDREYYSVQQHRHARLPVKWMALESLQTYRFTTKSDVWSFGVLLWELLTRGAPPYRHIDPFDLTHFLAQGRRLPQPEY----CPDSLYQVMQQCW 1218

[Close]

BLAST of Hepatocyte growth factor receptor vs. Ensembl Celegans
Match: egl-15 (Myoblast growth factor receptor egl-15 [Source:UniProtKB/Swiss-Prot;Acc:Q10656])

HSP 1 Score: 114.005 bits (284), Expect = 1.787e-25
Identity = 87/296 (29.39%), Postives = 137/296 (46.28%), Query Frame = 3

Query: 1803 IGRGNFSTVFKAKYSRSKDNAIPVAAKWLN-DKNDKTLNKIKTEL--FPSTFPHKNVLKSYGYCILKDQTYLISEL----------------------AFQDLLRYLQSNQ---------LPN--DRTCINFCLQVCQGMKFLSDDRKFIHRDLAARNILVFKDKDENVTLKISDFGLTIKLMNKNYYNSNSQGNFF--WLPDDEFKTGKFTVKTDIYSYGVVMWEIFS-GGKD---------VVKMRKSHRTLPKEFDDIKILDGAYNLMKGCWSVGDLQPNDFNSLIHLLKALL 2546
            +G G F  V+KA Y  +++N I VA K L    ++K L  + +E+  F     H+NVL+  G C      Y++ EL                      + Q+L  YL+  +         +PN   R  + F  QV QGM FL+  +K IHRDLAARN+LV     +   LKISDFGL+  +   +YY     G     W+  +   +  +TV++D++SYGV++WEI + GG              +++ +R  P      ++    Y+LM  CW     +   F +++  L  +L
Sbjct:  594 LGEGAFGEVWKATYKETENNEIAVAVKKLKMSAHEKELIDLVSEMETFKVIGEHENVLRLIGCCTGAGPLYVVVELCKHGNLRDFLRAHRPKEEKAKKSSQELTDYLEPRKASDKDDIELIPNLTQRHLVQFAWQVAQGMNFLAS-KKIIHRDLAARNVLV----GDGHVLKISDFGLSRDVHCNDYYRKRGNGRLPIKWMALEALDSNVYTVESDVWSYGVLLWEIMTLGGTPYPTIAMPELYANLKEGYRMEPPHLCPQEV----YHLMCSCWREKLEERPSFKTIVDYLDWML 880

[Close]

BLAST of Hepatocyte growth factor receptor vs. Ensembl Celegans
Match: egl-15 (Myoblast growth factor receptor egl-15 [Source:UniProtKB/Swiss-Prot;Acc:Q10656])

HSP 1 Score: 114.005 bits (284), Expect = 1.811e-25
Identity = 87/296 (29.39%), Postives = 137/296 (46.28%), Query Frame = 3

Query: 1803 IGRGNFSTVFKAKYSRSKDNAIPVAAKWLN-DKNDKTLNKIKTEL--FPSTFPHKNVLKSYGYCILKDQTYLISEL----------------------AFQDLLRYLQSNQ---------LPN--DRTCINFCLQVCQGMKFLSDDRKFIHRDLAARNILVFKDKDENVTLKISDFGLTIKLMNKNYYNSNSQGNFF--WLPDDEFKTGKFTVKTDIYSYGVVMWEIFS-GGKD---------VVKMRKSHRTLPKEFDDIKILDGAYNLMKGCWSVGDLQPNDFNSLIHLLKALL 2546
            +G G F  V+KA Y  +++N I VA K L    ++K L  + +E+  F     H+NVL+  G C      Y++ EL                      + Q+L  YL+  +         +PN   R  + F  QV QGM FL+  +K IHRDLAARN+LV     +   LKISDFGL+  +   +YY     G     W+  +   +  +TV++D++SYGV++WEI + GG              +++ +R  P      ++    Y+LM  CW     +   F +++  L  +L
Sbjct:  594 LGEGAFGEVWKATYKETENNEIAVAVKKLKMSAHEKELIDLVSEMETFKVIGEHENVLRLIGCCTGAGPLYVVVELCKHGNLRDFLRAHRPKEEKAKKSSQELTDYLEPRKASDKDDIELIPNLTQRHLVQFAWQVAQGMNFLAS-KKIIHRDLAARNVLV----GDGHVLKISDFGLSRDVHCNDYYRKRGNGRLPIKWMALEALDSNVYTVESDVWSYGVLLWEIMTLGGTPYPTIAMPELYANLKEGYRMEPPHLCPQEV----YHLMCSCWREKLEERPSFKTIVDYLDWML 880

[Close]

BLAST of Hepatocyte growth factor receptor vs. Ensembl Celegans
Match: egl-15 (Myoblast growth factor receptor egl-15 [Source:UniProtKB/Swiss-Prot;Acc:Q10656])

HSP 1 Score: 113.62 bits (283), Expect = 1.946e-25
Identity = 87/296 (29.39%), Postives = 137/296 (46.28%), Query Frame = 3

Query: 1803 IGRGNFSTVFKAKYSRSKDNAIPVAAKWLN-DKNDKTLNKIKTEL--FPSTFPHKNVLKSYGYCILKDQTYLISEL----------------------AFQDLLRYLQSNQ---------LPN--DRTCINFCLQVCQGMKFLSDDRKFIHRDLAARNILVFKDKDENVTLKISDFGLTIKLMNKNYYNSNSQGNFF--WLPDDEFKTGKFTVKTDIYSYGVVMWEIFS-GGKD---------VVKMRKSHRTLPKEFDDIKILDGAYNLMKGCWSVGDLQPNDFNSLIHLLKALL 2546
            +G G F  V+KA Y  +++N I VA K L    ++K L  + +E+  F     H+NVL+  G C      Y++ EL                      + Q+L  YL+  +         +PN   R  + F  QV QGM FL+  +K IHRDLAARN+LV     +   LKISDFGL+  +   +YY     G     W+  +   +  +TV++D++SYGV++WEI + GG              +++ +R  P      ++    Y+LM  CW     +   F +++  L  +L
Sbjct:  594 LGEGAFGEVWKATYKETENNEIAVAVKKLKMSAHEKELIDLVSEMETFKVIGEHENVLRLIGCCTGAGPLYVVVELCKHGNLRDFLRAHRPKEEKAKKSSQELTDYLEPRKASDKDDIELIPNLTQRHLVQFAWQVAQGMNFLAS-KKIIHRDLAARNVLV----GDGHVLKISDFGLSRDVHCNDYYRKRGNGRLPIKWMALEALDSNVYTVESDVWSYGVLLWEIMTLGGTPYPTIAMPELYANLKEGYRMEPPHLCPQEV----YHLMCSCWREKLEERPSFKTIVDYLDWML 880

[Close]

BLAST of Hepatocyte growth factor receptor vs. Ensembl Celegans
Match: egl-15 (Myoblast growth factor receptor egl-15 [Source:UniProtKB/Swiss-Prot;Acc:Q10656])

HSP 1 Score: 113.62 bits (283), Expect = 1.946e-25
Identity = 87/296 (29.39%), Postives = 137/296 (46.28%), Query Frame = 3

Query: 1803 IGRGNFSTVFKAKYSRSKDNAIPVAAKWLN-DKNDKTLNKIKTEL--FPSTFPHKNVLKSYGYCILKDQTYLISEL----------------------AFQDLLRYLQSNQ---------LPN--DRTCINFCLQVCQGMKFLSDDRKFIHRDLAARNILVFKDKDENVTLKISDFGLTIKLMNKNYYNSNSQGNFF--WLPDDEFKTGKFTVKTDIYSYGVVMWEIFS-GGKD---------VVKMRKSHRTLPKEFDDIKILDGAYNLMKGCWSVGDLQPNDFNSLIHLLKALL 2546
            +G G F  V+KA Y  +++N I VA K L    ++K L  + +E+  F     H+NVL+  G C      Y++ EL                      + Q+L  YL+  +         +PN   R  + F  QV QGM FL+  +K IHRDLAARN+LV     +   LKISDFGL+  +   +YY     G     W+  +   +  +TV++D++SYGV++WEI + GG              +++ +R  P      ++    Y+LM  CW     +   F +++  L  +L
Sbjct:  594 LGEGAFGEVWKATYKETENNEIAVAVKKLKMSAHEKELIDLVSEMETFKVIGEHENVLRLIGCCTGAGPLYVVVELCKHGNLRDFLRAHRPKEEKAKKSSQELTDYLEPRKASDKDDIELIPNLTQRHLVQFAWQVAQGMNFLAS-KKIIHRDLAARNVLV----GDGHVLKISDFGLSRDVHCNDYYRKRGNGRLPIKWMALEALDSNVYTVESDVWSYGVLLWEIMTLGGTPYPTIAMPELYANLKEGYRMEPPHLCPQEV----YHLMCSCWREKLEERPSFKTIVDYLDWML 880

[Close]

BLAST of Hepatocyte growth factor receptor vs. Ensembl Celegans
Match: egl-15 (Myoblast growth factor receptor egl-15 [Source:UniProtKB/Swiss-Prot;Acc:Q10656])

HSP 1 Score: 113.62 bits (283), Expect = 1.946e-25
Identity = 87/296 (29.39%), Postives = 137/296 (46.28%), Query Frame = 3

Query: 1803 IGRGNFSTVFKAKYSRSKDNAIPVAAKWLN-DKNDKTLNKIKTEL--FPSTFPHKNVLKSYGYCILKDQTYLISEL----------------------AFQDLLRYLQSNQ---------LPN--DRTCINFCLQVCQGMKFLSDDRKFIHRDLAARNILVFKDKDENVTLKISDFGLTIKLMNKNYYNSNSQGNFF--WLPDDEFKTGKFTVKTDIYSYGVVMWEIFS-GGKD---------VVKMRKSHRTLPKEFDDIKILDGAYNLMKGCWSVGDLQPNDFNSLIHLLKALL 2546
            +G G F  V+KA Y  +++N I VA K L    ++K L  + +E+  F     H+NVL+  G C      Y++ EL                      + Q+L  YL+  +         +PN   R  + F  QV QGM FL+  +K IHRDLAARN+LV     +   LKISDFGL+  +   +YY     G     W+  +   +  +TV++D++SYGV++WEI + GG              +++ +R  P      ++    Y+LM  CW     +   F +++  L  +L
Sbjct:  594 LGEGAFGEVWKATYKETENNEIAVAVKKLKMSAHEKELIDLVSEMETFKVIGEHENVLRLIGCCTGAGPLYVVVELCKHGNLRDFLRAHRPKEEKAKKSSQELTDYLEPRKASDKDDIELIPNLTQRHLVQFAWQVAQGMNFLAS-KKIIHRDLAARNVLV----GDGHVLKISDFGLSRDVHCNDYYRKRGNGRLPIKWMALEALDSNVYTVESDVWSYGVLLWEIMTLGGTPYPTIAMPELYANLKEGYRMEPPHLCPQEV----YHLMCSCWREKLEERPSFKTIVDYLDWML 880

[Close]

BLAST of Hepatocyte growth factor receptor vs. Ensembl Fly
Match: Btk29A (gene:FBgn0003502 transcript:FBtr0330693)

HSP 1 Score: 115.161 bits (287), Expect = 1.135e-26
Identity = 86/275 (31.27%), Postives = 142/275 (51.64%), Query Frame = 3

Query: 1764 EIKPEELQIEKTPIGRGNFSTVFKAKYSRSKDNAIPVAAKWLNDKND-----KTLNKIKTELFPSTFPHKNVLKSYGYCILKDQTYLISE-LAFQDLLRYLQSNQ---LPNDRTCINFCLQVCQGMKFLSDDRKFIHRDLAARNILVFKDKDENVTLKISDFGLTIKLMNKNYYNSNSQGNFF---WLPDDEFKTGKFTVKTDIYSYGVVMWEIFSGGK---------DVVKMRKSHRTLPKEFDDIKILDGAYNLMKGCWSVGDLQPNDFNSLI 2525
            EI P EL + +  +G G F  V + K+  S D A+ +  +    ++D     K + K++         H N+++ YG C      Y+++E +    LL YL+ ++   + N    ++ C+QV +GM +L +   +IHRDLAARN LV     ENV +K++DFGL   +++  Y  ++S G  F   W P +     +F+ K+D+++YGV+MWEIF+ GK         +VV+  +    L K     K +   Y++MK CWS G  +   F  L+
Sbjct:  198 EIHPMELMLMEE-LGSGQFGVVRRGKWRGSIDTAVKMMKEGTMSEDDFIEEAKVMTKLQ---------HPNLVQLYGVCSKHRPIYIVTEYMKHGSLLNYLRRHEKTLIGNMGLLLDMCIQVSKGMTYL-ERHNYIHRDLAARNCLV---GSENV-VKVADFGLARYVLDDQY--TSSGGTKFPIKWAPPEVLNYTRFSSKSDVWAYGVLMWEIFTCGKMPYGRLKNTEVVERVQRGIILEKPKSCAKEI---YDVMKLCWSHGPEERPAFRVLM 452

[Close]

BLAST of Hepatocyte growth factor receptor vs. Ensembl Fly
Match: Btk29A (gene:FBgn0003502 transcript:FBtr0330692)

HSP 1 Score: 115.546 bits (288), Expect = 2.379e-26
Identity = 86/275 (31.27%), Postives = 142/275 (51.64%), Query Frame = 3

Query: 1764 EIKPEELQIEKTPIGRGNFSTVFKAKYSRSKDNAIPVAAKWLNDKND-----KTLNKIKTELFPSTFPHKNVLKSYGYCILKDQTYLISE-LAFQDLLRYLQSNQ---LPNDRTCINFCLQVCQGMKFLSDDRKFIHRDLAARNILVFKDKDENVTLKISDFGLTIKLMNKNYYNSNSQGNFF---WLPDDEFKTGKFTVKTDIYSYGVVMWEIFSGGK---------DVVKMRKSHRTLPKEFDDIKILDGAYNLMKGCWSVGDLQPNDFNSLI 2525
            EI P EL + +  +G G F  V + K+  S D A+ +  +    ++D     K + K++         H N+++ YG C      Y+++E +    LL YL+ ++   + N    ++ C+QV +GM +L +   +IHRDLAARN LV     ENV +K++DFGL   +++  Y  ++S G  F   W P +     +F+ K+D+++YGV+MWEIF+ GK         +VV+  +    L K     K +   Y++MK CWS G  +   F  L+
Sbjct:  299 EIHPMELMLMEE-LGSGQFGVVRRGKWRGSIDTAVKMMKEGTMSEDDFIEEAKVMTKLQ---------HPNLVQLYGVCSKHRPIYIVTEYMKHGSLLNYLRRHEKTLIGNMGLLLDMCIQVSKGMTYL-ERHNYIHRDLAARNCLV---GSENV-VKVADFGLARYVLDDQY--TSSGGTKFPIKWAPPEVLNYTRFSSKSDVWAYGVLMWEIFTCGKMPYGRLKNTEVVERVQRGIILEKPKSCAKEI---YDVMKLCWSHGPEERPAFRVLM 553

[Close]

BLAST of Hepatocyte growth factor receptor vs. Ensembl Fly
Match: Btk29A (gene:FBgn0003502 transcript:FBtr0112835)

HSP 1 Score: 115.161 bits (287), Expect = 3.617e-26
Identity = 86/275 (31.27%), Postives = 142/275 (51.64%), Query Frame = 3

Query: 1764 EIKPEELQIEKTPIGRGNFSTVFKAKYSRSKDNAIPVAAKWLNDKND-----KTLNKIKTELFPSTFPHKNVLKSYGYCILKDQTYLISE-LAFQDLLRYLQSNQ---LPNDRTCINFCLQVCQGMKFLSDDRKFIHRDLAARNILVFKDKDENVTLKISDFGLTIKLMNKNYYNSNSQGNFF---WLPDDEFKTGKFTVKTDIYSYGVVMWEIFSGGK---------DVVKMRKSHRTLPKEFDDIKILDGAYNLMKGCWSVGDLQPNDFNSLI 2525
            EI P EL + +  +G G F  V + K+  S D A+ +  +    ++D     K + K++         H N+++ YG C      Y+++E +    LL YL+ ++   + N    ++ C+QV +GM +L +   +IHRDLAARN LV     ENV +K++DFGL   +++  Y  ++S G  F   W P +     +F+ K+D+++YGV+MWEIF+ GK         +VV+  +    L K     K +   Y++MK CWS G  +   F  L+
Sbjct:  337 EIHPMELMLMEE-LGSGQFGVVRRGKWRGSIDTAVKMMKEGTMSEDDFIEEAKVMTKLQ---------HPNLVQLYGVCSKHRPIYIVTEYMKHGSLLNYLRRHEKTLIGNMGLLLDMCIQVSKGMTYL-ERHNYIHRDLAARNCLV---GSENV-VKVADFGLARYVLDDQY--TSSGGTKFPIKWAPPEVLNYTRFSSKSDVWAYGVLMWEIFTCGKMPYGRLKNTEVVERVQRGIILEKPKSCAKEI---YDVMKLCWSHGPEERPAFRVLM 591

[Close]

BLAST of Hepatocyte growth factor receptor vs. Ensembl Fly
Match: Btk29A (gene:FBgn0003502 transcript:FBtr0079618)

HSP 1 Score: 115.161 bits (287), Expect = 3.617e-26
Identity = 86/275 (31.27%), Postives = 142/275 (51.64%), Query Frame = 3

Query: 1764 EIKPEELQIEKTPIGRGNFSTVFKAKYSRSKDNAIPVAAKWLNDKND-----KTLNKIKTELFPSTFPHKNVLKSYGYCILKDQTYLISE-LAFQDLLRYLQSNQ---LPNDRTCINFCLQVCQGMKFLSDDRKFIHRDLAARNILVFKDKDENVTLKISDFGLTIKLMNKNYYNSNSQGNFF---WLPDDEFKTGKFTVKTDIYSYGVVMWEIFSGGK---------DVVKMRKSHRTLPKEFDDIKILDGAYNLMKGCWSVGDLQPNDFNSLI 2525
            EI P EL + +  +G G F  V + K+  S D A+ +  +    ++D     K + K++         H N+++ YG C      Y+++E +    LL YL+ ++   + N    ++ C+QV +GM +L +   +IHRDLAARN LV     ENV +K++DFGL   +++  Y  ++S G  F   W P +     +F+ K+D+++YGV+MWEIF+ GK         +VV+  +    L K     K +   Y++MK CWS G  +   F  L+
Sbjct:  337 EIHPMELMLMEE-LGSGQFGVVRRGKWRGSIDTAVKMMKEGTMSEDDFIEEAKVMTKLQ---------HPNLVQLYGVCSKHRPIYIVTEYMKHGSLLNYLRRHEKTLIGNMGLLLDMCIQVSKGMTYL-ERHNYIHRDLAARNCLV---GSENV-VKVADFGLARYVLDDQY--TSSGGTKFPIKWAPPEVLNYTRFSSKSDVWAYGVLMWEIFTCGKMPYGRLKNTEVVERVQRGIILEKPKSCAKEI---YDVMKLCWSHGPEERPAFRVLM 591

[Close]

BLAST of Hepatocyte growth factor receptor vs. Ensembl Fly
Match: Btk29A (gene:FBgn0003502 transcript:FBtr0079615)

HSP 1 Score: 115.161 bits (287), Expect = 3.617e-26
Identity = 86/275 (31.27%), Postives = 142/275 (51.64%), Query Frame = 3

Query: 1764 EIKPEELQIEKTPIGRGNFSTVFKAKYSRSKDNAIPVAAKWLNDKND-----KTLNKIKTELFPSTFPHKNVLKSYGYCILKDQTYLISE-LAFQDLLRYLQSNQ---LPNDRTCINFCLQVCQGMKFLSDDRKFIHRDLAARNILVFKDKDENVTLKISDFGLTIKLMNKNYYNSNSQGNFF---WLPDDEFKTGKFTVKTDIYSYGVVMWEIFSGGK---------DVVKMRKSHRTLPKEFDDIKILDGAYNLMKGCWSVGDLQPNDFNSLI 2525
            EI P EL + +  +G G F  V + K+  S D A+ +  +    ++D     K + K++         H N+++ YG C      Y+++E +    LL YL+ ++   + N    ++ C+QV +GM +L +   +IHRDLAARN LV     ENV +K++DFGL   +++  Y  ++S G  F   W P +     +F+ K+D+++YGV+MWEIF+ GK         +VV+  +    L K     K +   Y++MK CWS G  +   F  L+
Sbjct:  337 EIHPMELMLMEE-LGSGQFGVVRRGKWRGSIDTAVKMMKEGTMSEDDFIEEAKVMTKLQ---------HPNLVQLYGVCSKHRPIYIVTEYMKHGSLLNYLRRHEKTLIGNMGLLLDMCIQVSKGMTYL-ERHNYIHRDLAARNCLV---GSENV-VKVADFGLARYVLDDQY--TSSGGTKFPIKWAPPEVLNYTRFSSKSDVWAYGVLMWEIFTCGKMPYGRLKNTEVVERVQRGIILEKPKSCAKEI---YDVMKLCWSHGPEERPAFRVLM 591

[Close]

BLAST of Hepatocyte growth factor receptor vs. Ensembl Zebrafish
Match: mst1ra (macrophage stimulating 1 receptor a [Source:ZFIN;Acc:ZDB-GENE-071218-2])

HSP 1 Score: 118.627 bits (296), Expect = 1.204e-26
Identity = 80/276 (28.99%), Postives = 141/276 (51.09%), Query Frame = 3

Query: 1767 IKPEELQIEKTPI-GRGNFSTVFKAKYSRSKDNAIPVAAKWLNDKND--KTLNKIKTELFPSTFPHKNVLKSYGYCILKDQTYLI--SELAFQDLLRYLQSNQL-PNDRTCINFCLQVCQGMKFLSDDRKFIHRDLAARNILVFKDKDENVTLKISDFGLTIKLMNKNYYN----SNSQGNFFWLPDDEFKTGKFTVKTDIYSYGVVMWEIFSGGK---------DVVKMRKSHRTLPKEFDDIKILDGAYNLMKGCWSVGDLQPNDFNSLIHLLK 2537
            I P++++I+   I G+G+F TV+    + S +     A K LN   D  +    ++  LF   F H +VL   G  +  D   L+    +   DL  +++S +  P  +  I F LQV +GM++L++ +KF+HRDLAARN ++    DE+ T+K++DFG+   + +K YY+      ++    W+  +  +T KFT K+D++SYGV+MWE+ + G          D+       R LP+        D  ++++  CW     +   F +L+  ++
Sbjct: 1040 ISPDKIKIQHEQIIGKGHFGTVYHGYLTDSDNKETHCAVKSLNRITDLEEVEQFLREGLFMKAFHHSHVLSLLGIVLPSDGLPLVILPYMKHGDLRHFIRSPERSPTVKDLIGFGLQVAKGMEYLAN-KKFVHRDLAARNCML----DESFTVKVADFGMARDVYDKEYYSIQDSKKAKLPVKWMALESLQTQKFTTKSDVWSYGVLMWELLTRGASPYPDVDPYDITPYLMQGRRLPQP---QYCFDSLWSVLMQCWHPEPEKRPGFTTLVQAVQ 1307

[Close]

BLAST of Hepatocyte growth factor receptor vs. Ensembl Zebrafish
Match: met (MET proto-oncogene, receptor tyrosine kinase [Source:ZFIN;Acc:ZDB-GENE-041014-1])

HSP 1 Score: 116.701 bits (291), Expect = 5.375e-26
Identity = 95/341 (27.86%), Postives = 157/341 (46.04%), Query Frame = 3

Query: 1611 DMAISLLENLYKISVNFTDSTSDEVIVQKDNIFIPKCIEIYNRDAKIFQLNEIKPEELQIEKTPIGRGNFSTVFKAKYSRSKDNAIPVAAKWLNDKND--KTLNKIKTELFPSTFPHKNVLKSYGYCILKDQTYLI--SELAFQDLLRYLQ-SNQLPNDRTCINFCLQVCQGMKFLSDDRKFIHRDLAARNILVFKDKDENVTLKISDFGLTIKLMNKNYYN-SNSQG---NFFWLPDDEFKTGKFTVKTDIYSYGVVMWEIFSGGKD----------VVKMRKSHRTLPKEFDDIKILDGAYNLMKGCWSVGDLQPNDFNSLIHLLKALLE*TSVNVFVL 2576
            D+A  LL +   I +    S   E++ +  ++ I        R+  +  +NEI           IGRG+F  VF              A K LN   D  +    +K  +    F H NVL   G C+  + + L+    +   DL  +++  +  P  +  + F LQV +GM++L+  +KF+HRDLAARN ++    DE+ T+K++DFGL   + +K YY+  N  G      W+  +  +T KFT K+D++S+GV++WE+ + G             V + +  R L  EF      D  YN+M  CW     +   F+ L+  + A+    S   ++L
Sbjct: 1042 DLASPLLPSTAPIDLG---SLHPELLKEVQHVVI-------AREDLLLHVNEI-----------IGRGHFGCVFHGTLLEPDGQKQHCAIKSLNRITDIEEVSQFLKEGIIMKDFSHPNVLSLLGICLPSEGSPLVVLPYMKHGDLRNFIRDESHNPTVKDLMGFGLQVAKGMEYLAS-KKFVHRDLAARNCML----DESYTVKVADFGLARDVYDKEYYSVHNKHGVKLPVKWMALESLQTHKFTTKSDVWSFGVLLWELMTRGAPPYSDVNSFDITVFLLQGRRLLQPEF----CPDALYNVMIECWHPKPERRPTFSELVSRISAIFSSFSGEHYIL 1352

[Close]

Query: 1611 DMAISLLENLYKISVNFTDSTSDEVIVQKDNIFIPKCIEIYNRDAKIFQLNEIKPEELQIEKTPIGRGNFSTVFKAKYSRSKDNAIPVAAKWLNDKND--KTLNKIKTELFPSTFPHKNVLKSYGYCILKDQTYLI--SELAFQDLLRYLQ-SNQLPNDRTCINFCLQVCQGMKFLSDDRKFIHRDLAARNILVFKDKDENVTLKISDFGLTIKLMNKNYYN-SNSQG---NFFWLPDDEFKTGKFTVKTDIYSYGVVMWEIFSGGKD----------VVKMRKSHRTLPKEFDDIKILDGAYNLMKGCWSVGDLQPNDFNSLIHLLKALLE*TSVNVFVL 2576
            D+A  LL +   I +    S   E++ +  ++ I        R+  +  +NEI           IGRG+F  VF              A K LN   D  +    +K  +    F H NVL   G C+  + + L+    +   DL  +++  +  P  +  + F LQV +GM++L+  +KF+HRDLAARN ++    DE+ T+K++DFGL   + +K YY+  N  G      W+  +  +T KFT K+D++S+GV++WE+ + G             V + +  R L  EF      D  YN+M  CW     +   F+ L+  + A+    S   ++L
Sbjct: 1042 DLASPLLPSTAPIDLG---SLHPELLKEVQHVVI-------AREDLLLHVNEI-----------IGRGHFGCVFHGTLLEPDGQKQHCAIKSLNRITDIEEVSQFLKEGIIMKDFSHPNVLSLLGICLPSEGSPLVVLPYMKHGDLRNFIRDESHNPTVKDLMGFGLQVAKGMEYLAS-KKFVHRDLAARNCML----DESYTVKVADFGLARDVYDKEYYSVHNKHGVKLPVKWMALESLQTHKFTTKSDVWSFGVLLWELMTRGAPPYSDVNSFDITVFLLQGRRLLQPEF----CPDALYNVMIECWHPKPERRPTFSELVSRISAIFSSFSGEHYIL 1352

[Close]

BLAST of Hepatocyte growth factor receptor vs. Ensembl Zebrafish
Match: btk (Bruton agammaglobulinemia tyrosine kinase [Source:ZFIN;Acc:ZDB-GENE-070531-1])

HSP 1 Score: 115.161 bits (287), Expect = 6.350e-26
Identity = 85/274 (31.02%), Postives = 137/274 (50.00%), Query Frame = 3

Query: 1764 EIKPEELQIEKTPIGRGNFSTVFKAKYSRSKDNAIPVAAKWLNDKNDKTLNKIKTELFPSTFPHKNVLKSYGYCILKDQTYLISE-LAFQDLLRYLQSNQL-PNDRTCINFCLQVCQGMKFLSDDRKFIHRDLAARNILVFKDKDENVTLKISDFGLTIKLMNKNYYNS-NSQGNFFWLPDDEFKTGKFTVKTDIYSYGVVMWEIFSGGKD----------VVKMRKSHRTLPKEFDDIKILDGAYNLMKGCWSVGDLQPNDFNSLIHLLKALL 2546
            EI P +L   +  +G G F  V   K+    D AI +  +    ++D  + + K  +      H N+++ YG C  +   Y+++E LA   LL YLQ   L P     +  C  V +GMK+L  + +FIHRDLAARN LV    D N T+K++DFGL+  +++  Y +S  S+    W P +     KF+ K+DI+++GV+MWEI++ G+           V K+   HR    +  +    +  + +M  CW     +   F  L+ ++K LL
Sbjct:  375 EIDPRQLTFIRE-LGNGQFGVVKYGKWQGRHDVAIKMVKEGSMSEDD-FIEEAKVMM---KLCHGNLVQLYGVCTKQRPIYIVTEYLANGCLLNYLQEGLLNPTSIALLEMCKDVSEGMKYLEAN-QFIHRDLAARNCLV----DSNGTIKVTDFGLSRYVLDDEYTSSVGSKFPVRWSPPEVLLYCKFSSKSDIWAFGVLMWEIYTQGRMPYDRWNNTEIVEKISAGHRLYRPQMAN----ENVFAIMNSCWHERPDERPTFQELVGVIKDLL 634

[Close]

BLAST of Hepatocyte growth factor receptor vs. Ensembl Zebrafish
Match: BX544890.1 (Bruton agammaglobulinemia tyrosine kinase [Source:NCBI gene;Acc:568653])

HSP 1 Score: 112.849 bits (281), Expect = 2.722e-25
Identity = 84/274 (30.66%), Postives = 136/274 (49.64%), Query Frame = 3

Query: 1764 EIKPEELQIEKTPIGRGNFSTVFKAKYSRSKDNAIPVAAKWLNDKNDKTLNKIKTELFPSTFPHKNVLKSYGYCILKDQTYLISE-LAFQDLLRYLQSN-QLPNDRTCINFCLQVCQGMKFLSDDRKFIHRDLAARNILVFKDKDENVTLKISDFGLTIKLMNKNYYNS-NSQGNFFWLPDDEFKTGKFTVKTDIYSYGVVMWEIFSGGKD----------VVKMRKSHRTLPKEFDDIKILDGAYNLMKGCWSVGDLQPNDFNSLIHLLKALL 2546
            EI P +L   +  +G G F  V   K+    D AI +  +    ++D  + + K  +      H N+++ YG C  +   Y+++E LA   LL YLQ     P     +  C  V +GMK+L  + +FIHRDLAARN LV    D N T+K++DFGL+  +++  Y +S  S+    W P +     KF+ K+DI+++GV+MWEI++ G+           V K+   HR    +  +    +  + +M  CW     +   F  L+ ++K LL
Sbjct:  354 EIDPRQLTFIRE-LGNGQFGVVKYGKWQGRHDVAIKMVKEGSMSEDD-FIEEAKVMM---KLCHGNLVQLYGVCTKQRPIYIVTEYLANGCLLNYLQERLSNPTSIVLLEMCKDVSEGMKYLEAN-QFIHRDLAARNCLV----DSNGTIKVTDFGLSRYVLDDEYTSSVGSKFPVRWSPPEVLLYCKFSSKSDIWAFGVLMWEIYTQGRMPYDRWNNTEIVEKISAGHRLYRPQMAN----ENVFAIMNSCWHERPDERPTFKELVEVIKDLL 613

[Close]

BLAST of Hepatocyte growth factor receptor vs. Ensembl Xenopus
Match: fez1 (fasciculation and elongation protein zeta 1 [Source:Xenbase;Acc:XB-GENE-945356])

HSP 1 Score: 110.153 bits (274), Expect = 5.882e-24
Identity = 77/264 (29.17%), Postives = 134/264 (50.76%), Query Frame = 3

Query: 1803 IGRGNFSTVFKAKYSRSKDNAIPVAAKWLNDKND--KTLNKIKTELFPSTFPHKNVLKSYGYCILKDQTYLISELAFQ---DLLRYLQSNQL-PNDRTCINFCLQVCQGMKFLSDDRKFIHRDLAARNILVFKDKDENVTLKISDFGLTIKLMNKNYY----NSNSQGNFFWLPDDEFKTGKFTVKTDIYSYGVVMWEIFSGGK---------DVVK-MRKSHRTLPKEFDDIKILDGAYNLMKGCWSVGDLQPNDFNSLIHLL 2534
            IG+G+F +V+   Y       +  A K LN   D  +    ++  +   +F H NVL   G  + ++   L+  L F    DL  +++  +  P  +  + F LQV +GM++L++ RKF+HRDLAARN ++    DE   +K++DFGL   + +K YY    + N++    W+  +  +T KFT K+D++S+GV++WE+ + G          D+ + + +  R    E+      D  Y+LM  CW   + QP +  +   L+
Sbjct:  785 IGKGHFGSVYHGTYVDEDQQEVHCAVKSLNRITDLEEVEEFLREGILMKSFHHPNVLSLIGIFLPQEGLPLVV-LPFMKHGDLRHFIRCQERNPTVKDLVGFGLQVSRGMEYLAN-RKFVHRDLAARNCML----DETFHVKVADFGLARDVFDKEYYSVRRHKNARLPVKWMALESLQTQKFTTKSDVWSFGVLLWELMTRGAPPYPDVDPYDITRYLFRGRRLAQPEY----CPDPLYSLMLSCW---NPQPEERPTFTQLV 1035

[Close]

BLAST of Hepatocyte growth factor receptor vs. Ensembl Xenopus
Match: fez1 (fasciculation and elongation protein zeta 1 [Source:Xenbase;Acc:XB-GENE-945356])

HSP 1 Score: 110.153 bits (274), Expect = 5.914e-24
Identity = 77/264 (29.17%), Postives = 134/264 (50.76%), Query Frame = 3

Query: 1803 IGRGNFSTVFKAKYSRSKDNAIPVAAKWLNDKND--KTLNKIKTELFPSTFPHKNVLKSYGYCILKDQTYLISELAFQ---DLLRYLQSNQL-PNDRTCINFCLQVCQGMKFLSDDRKFIHRDLAARNILVFKDKDENVTLKISDFGLTIKLMNKNYY----NSNSQGNFFWLPDDEFKTGKFTVKTDIYSYGVVMWEIFSGGK---------DVVK-MRKSHRTLPKEFDDIKILDGAYNLMKGCWSVGDLQPNDFNSLIHLL 2534
            IG+G+F +V+   Y       +  A K LN   D  +    ++  +   +F H NVL   G  + ++   L+  L F    DL  +++  +  P  +  + F LQV +GM++L++ RKF+HRDLAARN ++    DE   +K++DFGL   + +K YY    + N++    W+  +  +T KFT K+D++S+GV++WE+ + G          D+ + + +  R    E+      D  Y+LM  CW   + QP +  +   L+
Sbjct:  768 IGKGHFGSVYHGTYVDEDQQEVHCAVKSLNRITDLEEVEEFLREGILMKSFHHPNVLSLIGIFLPQEGLPLVV-LPFMKHGDLRHFIRCQERNPTVKDLVGFGLQVSRGMEYLAN-RKFVHRDLAARNCML----DETFHVKVADFGLARDVFDKEYYSVRRHKNARLPVKWMALESLQTQKFTTKSDVWSFGVLLWELMTRGAPPYPDVDPYDITRYLFRGRRLAQPEY----CPDPLYSLMLSCW---NPQPEERPTFTQLV 1018

[Close]

BLAST of Hepatocyte growth factor receptor vs. Ensembl Xenopus
Match: fez1 (fasciculation and elongation protein zeta 1 [Source:Xenbase;Acc:XB-GENE-945356])

HSP 1 Score: 110.153 bits (274), Expect = 6.260e-24
Identity = 77/264 (29.17%), Postives = 134/264 (50.76%), Query Frame = 3

Query: 1803 IGRGNFSTVFKAKYSRSKDNAIPVAAKWLNDKND--KTLNKIKTELFPSTFPHKNVLKSYGYCILKDQTYLISELAFQ---DLLRYLQSNQL-PNDRTCINFCLQVCQGMKFLSDDRKFIHRDLAARNILVFKDKDENVTLKISDFGLTIKLMNKNYY----NSNSQGNFFWLPDDEFKTGKFTVKTDIYSYGVVMWEIFSGGK---------DVVK-MRKSHRTLPKEFDDIKILDGAYNLMKGCWSVGDLQPNDFNSLIHLL 2534
            IG+G+F +V+   Y       +  A K LN   D  +    ++  +   +F H NVL   G  + ++   L+  L F    DL  +++  +  P  +  + F LQV +GM++L++ RKF+HRDLAARN ++    DE   +K++DFGL   + +K YY    + N++    W+  +  +T KFT K+D++S+GV++WE+ + G          D+ + + +  R    E+      D  Y+LM  CW   + QP +  +   L+
Sbjct:  688 IGKGHFGSVYHGTYVDEDQQEVHCAVKSLNRITDLEEVEEFLREGILMKSFHHPNVLSLIGIFLPQEGLPLVV-LPFMKHGDLRHFIRCQERNPTVKDLVGFGLQVSRGMEYLAN-RKFVHRDLAARNCML----DETFHVKVADFGLARDVFDKEYYSVRRHKNARLPVKWMALESLQTQKFTTKSDVWSFGVLLWELMTRGAPPYPDVDPYDITRYLFRGRRLAQPEY----CPDPLYSLMLSCW---NPQPEERPTFTQLV 938

[Close]

BLAST of Hepatocyte growth factor receptor vs. Ensembl Xenopus
Match: fez1 (fasciculation and elongation protein zeta 1 [Source:Xenbase;Acc:XB-GENE-945356])

HSP 1 Score: 110.153 bits (274), Expect = 6.537e-24
Identity = 77/264 (29.17%), Postives = 134/264 (50.76%), Query Frame = 3

Query: 1803 IGRGNFSTVFKAKYSRSKDNAIPVAAKWLNDKND--KTLNKIKTELFPSTFPHKNVLKSYGYCILKDQTYLISELAFQ---DLLRYLQSNQL-PNDRTCINFCLQVCQGMKFLSDDRKFIHRDLAARNILVFKDKDENVTLKISDFGLTIKLMNKNYY----NSNSQGNFFWLPDDEFKTGKFTVKTDIYSYGVVMWEIFSGGK---------DVVK-MRKSHRTLPKEFDDIKILDGAYNLMKGCWSVGDLQPNDFNSLIHLL 2534
            IG+G+F +V+   Y       +  A K LN   D  +    ++  +   +F H NVL   G  + ++   L+  L F    DL  +++  +  P  +  + F LQV +GM++L++ RKF+HRDLAARN ++    DE   +K++DFGL   + +K YY    + N++    W+  +  +T KFT K+D++S+GV++WE+ + G          D+ + + +  R    E+      D  Y+LM  CW   + QP +  +   L+
Sbjct: 1061 IGKGHFGSVYHGTYVDEDQQEVHCAVKSLNRITDLEEVEEFLREGILMKSFHHPNVLSLIGIFLPQEGLPLVV-LPFMKHGDLRHFIRCQERNPTVKDLVGFGLQVSRGMEYLAN-RKFVHRDLAARNCML----DETFHVKVADFGLARDVFDKEYYSVRRHKNARLPVKWMALESLQTQKFTTKSDVWSFGVLLWELMTRGAPPYPDVDPYDITRYLFRGRRLAQPEY----CPDPLYSLMLSCW---NPQPEERPTFTQLV 1311

[Close]

BLAST of Hepatocyte growth factor receptor vs. Ensembl Xenopus
Match: drc1 (dynein regulatory complex subunit 1 [Source:Xenbase;Acc:XB-GENE-5967064])

HSP 1 Score: 105.916 bits (263), Expect = 1.390e-23
Identity = 77/258 (29.84%), Postives = 131/258 (50.78%), Query Frame = 3

Query: 1803 IGRGNFSTVFKAKYSRSKDNAIPVAAKWLNDKNDKTLNK--IKTELFPSTFPHKNVLKSYGYCILKDQTYLISELAFQ-DLLRYLQSNQLPNDRTCINFCLQVCQGMKFLSDDRKFIHRDLAARNILVFKDKDENVTLKISDFGLTIKLMNKNYYNSNSQGNFFWLPDDEFKTGKFTVKTDIYSYGVVMWEIFSGGKDVVKMRKSHRTLPKEF----DDIKILDG----AYNLMKGCWSVGDLQPNDFNSLIHLLKAL 2543
            +G GNF  V +  +       + VA K +  K D T     +K   F  T  HKN+L  Y  C + D  Y+++EL  + DLL YL+     +    ++   QV +GM++L + +  IHRDLAARN+L+ +    N   KI+DFG+   +++  Y +++ +  F W   +  + G++TVK+D++S+G++++EI S G        ++  L  EF      +K         YN+M  CW+    +   F+ L  +L+ L
Sbjct:  153 LGMGNFGQVHEGLWK----GKLKVAVKTI--KRDATSQDLFVKETAFLKTLHHKNLLSLYAVCSVGDPYYIVTELVPRGDLLNYLREKDELDVEGQLDIATQVAEGMRYL-ESQNCIHRDLAARNVLMGR----NNICKIADFGMARVILDSYYVSASKEIPFKWTAPEAVEYGRYTVKSDVWSFGILLYEIMSLGMQPYPALSNYEVL--EFLNRGQRMKAPPSCSTRVYNIMLTCWAWNPNERPSFDDLRTMLENL 397

[Close]

BLAST of Hepatocyte growth factor receptor vs. Ensembl Mouse
Match: Met (met proto-oncogene [Source:MGI Symbol;Acc:MGI:96969])

HSP 1 Score: 115.161 bits (287), Expect = 1.690e-25
Identity = 79/267 (29.59%), Postives = 138/267 (51.69%), Query Frame = 3

Query: 1803 IGRGNFSTVFKAKYSRSKDNAIPVAAKWLNDKND-KTLNKIKTE-LFPSTFPHKNVLKSYGYCILKDQTYLI--SELAFQDLLRYLQS-NQLPNDRTCINFCLQVCQGMKFLSDDRKFIHRDLAARNILVFKDKDENVTLKISDFGLTIKLMNKNYYN----SNSQGNFFWLPDDEFKTGKFTVKTDIYSYGVVMWEIFSGGKD----------VVKMRKSHRTLPKEFDDIKILDGAYNLMKGCWSV-GDLQPNDFNSLIHLLKAL 2543
            IGRG+F  V+      +    I  A K LN   D + +++  TE +    F H NVL   G C+  + + L+    +   DL  ++++    P  +  I F LQV +GMK+L+  +KF+HRDLAARN ++    DE  T+K++DFGL   + +K YY+    + ++    W+  +  +T KFT K+D++S+GV++WE+ + G             + + +  R L  E+      D  Y +M  CW    +++P+ F+ L+  + ++
Sbjct: 1082 IGRGHFGCVYHGTLLDNDGKKIHCAVKSLNRITDIEEVSQFLTEGIIMKDFSHPNVLSLLGICLRSEGSPLVVLPYMKHGDLRNFIRNETHNPTVKDLIGFGLQVAKGMKYLAS-KKFVHRDLAARNCML----DEKFTVKVADFGLARDMYDKEYYSVHNKTGAKLPVKWMALESLQTQKFTTKSDVWSFGVLLWELMTRGAPPYPDVNTFDITIYLLQGRRLLQPEY----CPDALYEVMLKCWHPKAEMRPS-FSELVSRISSI 1338

[Close]

Query: 1803 IGRGNFSTVFKAKYSRSKDNAIPVAAKWLNDKND-KTLNKIKTE-LFPSTFPHKNVLKSYGYCILKDQTYLI--SELAFQDLLRYLQS-NQLPNDRTCINFCLQVCQGMKFLSDDRKFIHRDLAARNILVFKDKDENVTLKISDFGLTIKLMNKNYYN----SNSQGNFFWLPDDEFKTGKFTVKTDIYSYGVVMWEIFSGGKD----------VVKMRKSHRTLPKEFDDIKILDGAYNLMKGCWSV-GDLQPNDFNSLIHLLKAL 2543
            IGRG+F  V+      +    I  A K LN   D + +++  TE +    F H NVL   G C+  + + L+    +   DL  ++++    P  +  I F LQV +GMK+L+  +KF+HRDLAARN ++    DE  T+K++DFGL   + +K YY+    + ++    W+  +  +T KFT K+D++S+GV++WE+ + G             + + +  R L  E+      D  Y +M  CW    +++P+ F+ L+  + ++
Sbjct: 1082 IGRGHFGCVYHGTLLDNDGKKIHCAVKSLNRITDIEEVSQFLTEGIIMKDFSHPNVLSLLGICLRSEGSPLVVLPYMKHGDLRNFIRNETHNPTVKDLIGFGLQVAKGMKYLAS-KKFVHRDLAARNCML----DEKFTVKVADFGLARDMYDKEYYSVHNKTGAKLPVKWMALESLQTQKFTTKSDVWSFGVLLWELMTRGAPPYPDVNTFDITIYLLQGRRLLQPEY----CPDALYEVMLKCWHPKAEMRPS-FSELVSRISSI 1338

[Close]

Query: 1803 IGRGNFSTVFKAKYSRSKDNAIPVAAKWLNDKND-KTLNKIKTE-LFPSTFPHKNVLKSYGYCILKDQTYLI--SELAFQDLLRYLQS-NQLPNDRTCINFCLQVCQGMKFLSDDRKFIHRDLAARNILVFKDKDENVTLKISDFGLTIKLMNKNYYN----SNSQGNFFWLPDDEFKTGKFTVKTDIYSYGVVMWEIFSGGKD----------VVKMRKSHRTLPKEFDDIKILDGAYNLMKGCWSV-GDLQPNDFNSLIHLLKAL 2543
            IGRG+F  V+      +    I  A K LN   D + +++  TE +    F H NVL   G C+  + + L+    +   DL  ++++    P  +  I F LQV +GMK+L+  +KF+HRDLAARN ++    DE  T+K++DFGL   + +K YY+    + ++    W+  +  +T KFT K+D++S+GV++WE+ + G             + + +  R L  E+      D  Y +M  CW    +++P+ F+ L+  + ++
Sbjct: 1082 IGRGHFGCVYHGTLLDNDGKKIHCAVKSLNRITDIEEVSQFLTEGIIMKDFSHPNVLSLLGICLRSEGSPLVVLPYMKHGDLRNFIRNETHNPTVKDLIGFGLQVAKGMKYLAS-KKFVHRDLAARNCML----DEKFTVKVADFGLARDMYDKEYYSVHNKTGAKLPVKWMALESLQTQKFTTKSDVWSFGVLLWELMTRGAPPYPDVNTFDITIYLLQGRRLLQPEY----CPDALYEVMLKCWHPKAEMRPS-FSELVSRISSI 1338

[Close]

BLAST of Hepatocyte growth factor receptor vs. Ensembl Mouse
Match: Bmx (BMX non-receptor tyrosine kinase [Source:MGI Symbol;Acc:MGI:1101778])

HSP 1 Score: 112.079 bits (279), Expect = 5.966e-25
Identity = 82/276 (29.71%), Postives = 139/276 (50.36%), Query Frame = 3

Query: 1764 EIKPEELQIEKTPIGRGNFSTVFKAKYSRSKDNAIPVAAKWLNDKNDKTLNKIKTELFPSTFPHKNVLKSYGYCILKDQTYLISELAFQD-LLRYLQSNQLPNDRTC--INFCLQVCQGMKFLSDDRKFIHRDLAARNILVFKDKDENVTLKISDFGLTIKLMNKNYYNS-NSQGNFFWLPDDEFKTGKFTVKTDIYSYGVVMWEIFSGGKD----------VVKMRKSHRTLPKEFDDIKILDGAYNLMKGCWSVGDLQPNDFNSLIHLLKALLE 2549
            E+K EE+ + K  +G G F  V   ++    D A+ +  +    + D+   + +T +      H  ++K YG C  K   Y+++E      LL YL+S+      +C  +  C  VC+GM FL +  +FIHRDLAARN LV    D ++++K+SDFG+T  +++  Y +S  ++    W   + F   K++ K+D++++G++MWE+FS GK           VVK+ + HR    +       D  Y +M  CW     +   F  L+  ++ L E
Sbjct:  387 ELKREEITLLKE-LGNGQFGVVQLGQWKGQYDVAVKMIKEGAMSE-DEFFQEAQTMM---KLSHPKLVKFYGVCSKKYPIYIVTEYITNGCLLNYLKSHG-KGLESCQLLEMCYDVCEGMAFL-ESHQFIHRDLAARNCLV----DSDLSVKVSDFGMTRYVLDDQYVSSVGTKFPVKWSAPEVFHYFKYSSKSDVWAFGILMWEVFSLGKQPYDLYDNSEVVVKVSQGHRLYRPQLAS----DTIYQIMYSCWHELPEKRPTFQQLLSAIEPLRE 647

[Close]

BLAST of Hepatocyte growth factor receptor vs. Ensembl Mouse
Match: Bmx (BMX non-receptor tyrosine kinase [Source:MGI Symbol;Acc:MGI:1101778])

HSP 1 Score: 112.079 bits (279), Expect = 6.385e-25
Identity = 82/276 (29.71%), Postives = 139/276 (50.36%), Query Frame = 3

Query: 1764 EIKPEELQIEKTPIGRGNFSTVFKAKYSRSKDNAIPVAAKWLNDKNDKTLNKIKTELFPSTFPHKNVLKSYGYCILKDQTYLISELAFQD-LLRYLQSNQLPNDRTC--INFCLQVCQGMKFLSDDRKFIHRDLAARNILVFKDKDENVTLKISDFGLTIKLMNKNYYNS-NSQGNFFWLPDDEFKTGKFTVKTDIYSYGVVMWEIFSGGKD----------VVKMRKSHRTLPKEFDDIKILDGAYNLMKGCWSVGDLQPNDFNSLIHLLKALLE 2549
            E+K EE+ + K  +G G F  V   ++    D A+ +  +    + D+   + +T +      H  ++K YG C  K   Y+++E      LL YL+S+      +C  +  C  VC+GM FL +  +FIHRDLAARN LV    D ++++K+SDFG+T  +++  Y +S  ++    W   + F   K++ K+D++++G++MWE+FS GK           VVK+ + HR    +       D  Y +M  CW     +   F  L+  ++ L E
Sbjct:  391 ELKREEITLLKE-LGNGQFGVVQLGQWKGQYDVAVKMIKEGAMSE-DEFFQEAQTMM---KLSHPKLVKFYGVCSKKYPIYIVTEYITNGCLLNYLKSHG-KGLESCQLLEMCYDVCEGMAFL-ESHQFIHRDLAARNCLV----DSDLSVKVSDFGMTRYVLDDQYVSSVGTKFPVKWSAPEVFHYFKYSSKSDVWAFGILMWEVFSLGKQPYDLYDNSEVVVKVSQGHRLYRPQLAS----DTIYQIMYSCWHELPEKRPTFQQLLSAIEPLRE 651

[Close]

BLAST of Hepatocyte growth factor receptor vs. UniProt/SwissProt
Match: sp|Q2IBC0|MET_RHIFE (Hepatocyte growth factor receptor OS=Rhinolophus ferrumequinum OX=59479 GN=MET PE=3 SV=1)

HSP 1 Score: 123.635 bits (309), Expect = 2.925e-27
Identity = 103/363 (28.37%), Postives = 171/363 (47.11%), Query Frame = 3

Query: 1518 EDLKDHKVSQSSFRETKCLLKEL--ILKAFQSQDMAISLLENLYKISVNFTDSTSDEVIVQKDNIFIPKCIEIYNRDAKIFQLNEIKPEELQIEKTPIGRGNFSTVFKAKYSRSKDNAIPVAAKWLNDKND-KTLNKIKTE-LFPSTFPHKNVLKSYGYCILKDQTYLI--SELAFQDLLRYLQS-NQLPNDRTCINFCLQVCQGMKFLSDDRKFIHRDLAARNILVFKDKDENVTLKISDFGLTIKLMNKNYYNSNSQGN----FFWLPDDEFKTGKFTVKTDIYSYGVVMWEIFSGGKD----------VVKMRKSHRTLPKEFDDIKILDGAYNLMKGCWSVGDLQPNDFNSLIHLLKAL 2543
            ED   +     S R+ +C L +L  IL    S D++  LL+N  +I ++   + + E++    ++ I            I   NE+           IGRG+F  V+      + D  I  A K LN   D   +++  TE +    F H NVL   G C+  + + L+    +   DL  ++++    P  +  I F LQV +GMK+L+  +KF+HRDLAARN ++    DEN T+K++DFGL   + +K YY+ +++        W+  +  +T KFT K+D++S+GV++WE+ + G             V + +  R L  E+      D  Y +M  CW     Q   F  L+  + A+
Sbjct: 1009 EDQFANSSQNGSCRQVQCPLMDLSPILPGGDS-DISSPLLQNTVRIDLS---ALNPELVQAVQHVVI-------GPSRLIVHFNEV-----------IGRGHFGCVYHGTLLDNDDKKIHCAVKSLNRITDIGEVSQFLTEGIIMKDFSHPNVLSLLGICLRSEGSPLVVLPYMKHGDLRNFIRNETHNPTVKDLIGFGLQVAKGMKYLAS-KKFVHRDLAARNCML----DENFTVKVADFGLARDVYDKEYYSVHNKTGAKLPVKWMALESLQTQKFTTKSDVWSFGVLLWELMTRGAPPYPDVNTFDITVYLLQGRRLLQPEY----CPDHLYEVMLKCWHPKAEQRPSFAELVSRISAI 1340

[Close]

BLAST of Hepatocyte growth factor receptor vs. UniProt/SwissProt
Match: sp|P23049|SEA_AVIET (Tyrosine-protein kinase transforming protein SEA OS=Avian erythroblastosis virus (strain S13) OX=11863 GN=V-SEA PE=3 SV=2)

HSP 1 Score: 116.316 bits (290), Expect = 1.218e-26
Identity = 86/300 (28.67%), Postives = 145/300 (48.33%), Query Frame = 3

Query: 1719 CIEIYNRDAKIFQLNEIK----PEELQIEKTP--IGRGNFSTVFKAKYSRSKDNAIPVAAKWLNDKN--DKTLNKIKTELFPSTFPHKNVLKSYGYCILKDQTYLI--SELAFQDLLRYLQSNQL-PNDRTCINFCLQVCQGMKFLSDDRKFIHRDLAARNILVFKDKDENVTLKISDFGLTIKLMNKNYY----NSNSQGNFFWLPDDEFKTGKFTVKTDIYSYGVVMWEIFSGGK---------DVVKMRKSHRTLPKEFDDIKILDGAYNLMKGCWSVGDLQPNDFNSLIHLLKALL 2546
            C+E    D +   L E+K    PEE  I      IGRG+F +V+   Y       +  A K L+     ++    ++  +    F H  VL   G C+ +    L+    +   DL  ++++ +  P  +  I F LQV  GM++L+  +KF+HRDLAARN ++    DE +T+K++DFGL   +  K YY    + +++    W+  +  +T KFT K+D++S+GV+MWE+ + G          D+ +     R LP+        D  Y +M  CW+    +   F+ L+  L+ +L
Sbjct:   36 CLE----DLRPELLEEVKDILIPEERLITHRSRVIGRGHFGSVYHGTYMDPLLGNLHCAVKSLHRITYLEEVEEFLREGILMKGFHHPQVLSLLGVCLPRHGLPLVVLPYMRHGDLRHFVRAQERSPTVKELIGFGLQVALGMEYLAQ-KKFVHRDLAARNCML----DETLTVKVADFGLARDVFGKEYYSIRQHRHAKLPVRWMALESLQTQKFTTKSDVWSFGVLMWELLTRGASPYPEVDPYDMARYLLRGRRLPQ---PQPCPDTLYGVMLSCWAPTPEERPSFSGLVCELERVL 323

[Close]

BLAST of Hepatocyte growth factor receptor vs. UniProt/SwissProt
Match: sp|Q00PJ8|MET_ATEAB (Hepatocyte growth factor receptor OS=Atelerix albiventris OX=9368 GN=MET PE=3 SV=1)

HSP 1 Score: 121.324 bits (303), Expect = 1.547e-26
Identity = 86/268 (32.09%), Postives = 138/268 (51.49%), Query Frame = 3

Query: 1803 IGRGNFSTVFKAKYSRSKDNAIPVAAKWLNDKND-KTLNKIKTE-LFPSTFPHKNVLKSYGYCILKDQTYLI--SELAFQDLLRYLQS-NQLPNDRTCINFCLQVCQGMKFLSDDRKFIHRDLAARNILVFKDKDENVTLKISDFGLTIKLMNKNYYN-SNSQGNFF---WLPDDEFKTGKFTVKTDIYSYGVVMWEIFSGGKD----------VVKMRKSHRTLPKEFDDIKILDGAYNLMKGCWSV-GDLQPNDFNSLIHLLKALL 2546
            IGRG+F  V+      + D  I  A K LN   D   +++  TE +    F H NVL   G C+  + + L+    +   DL  ++++    P  +  I F LQV +GMK+L+  +KF+HRDLAARN ++    DEN T+K++DFGL   + +K YY+  N  G      W+  +  +T KFT K+D++S+GV++WE+ + G             V + +  R L  E+      D  Y +M  CW    +L+P+ F+ L+  + A+ 
Sbjct: 1085 IGRGHFGCVYHGTLLDNDDKKIHCAVKSLNRITDIGEVSQFLTEGIIMKDFSHPNVLSLLGICLRSEGSPLVVLPYMKHGDLRNFIRNETHNPTVKDLIGFGLQVAKGMKYLAS-KKFVHRDLAARNCML----DENFTVKVADFGLARDMYDKEYYSVHNKTGAKLPVKWMALESLQTQKFTTKSDVWSFGVLLWELMTRGAPPYPDVNTFDITVYLLQGRRLLQPEY----CPDPLYEVMLKCWHPKAELRPS-FSELVSRISAIF 1342

[Close]

BLAST of Hepatocyte growth factor receptor vs. UniProt/SwissProt
Match: sp|Q07E37|MET_NEONE (Hepatocyte growth factor receptor OS=Neofelis nebulosa OX=61452 GN=MET PE=3 SV=1)

HSP 1 Score: 120.553 bits (301), Expect = 2.544e-26
Identity = 86/268 (32.09%), Postives = 137/268 (51.12%), Query Frame = 3

Query: 1803 IGRGNFSTVFKAKYSRSKDNAIPVAAKWLNDKND-KTLNKIKTE-LFPSTFPHKNVLKSYGYCILKDQTYLI--SELAFQDLLRYLQS-NQLPNDRTCINFCLQVCQGMKFLSDDRKFIHRDLAARNILVFKDKDENVTLKISDFGLTIKLMNKNYYN-SNSQGNFF---WLPDDEFKTGKFTVKTDIYSYGVVMWEIFSGGKD----------VVKMRKSHRTLPKEFDDIKILDGAYNLMKGCWSV-GDLQPNDFNSLIHLLKALL 2546
            IGRG+F  V+      S D  I  A K LN   D   +++  TE +    F H NVL   G C+  + + L+    +   DL  ++++    P  +  I F LQV +GMK+L+  +KF+HRDLAARN ++    DE  T+K++DFGL   + +K YY+  N  G      W+  +  +T KFT K+D++S+GV++WE+ + G             V + +  R L  E+      D  Y +M  CW    +L+P+ F+ L+  + A+ 
Sbjct: 1085 IGRGHFGCVYHGTLLDSDDKKIHCAVKSLNRITDIGEVSQFLTEGIIMKDFSHPNVLSLLGICLRSEGSPLVVLPYMKHGDLRNFIRNETHNPTVKDLIGFGLQVAKGMKYLAS-KKFVHRDLAARNCML----DEKFTVKVADFGLARDMYDKEYYSVHNKTGAKLPVKWMALESLQTQKFTTKSDVWSFGVLLWELMTRGAPPYPDVNTFDITVYLLQGRRLLQPEY----CPDPLYEVMLKCWHPKAELRPS-FSELVSRISAIF 1342

[Close]

BLAST of Hepatocyte growth factor receptor vs. UniProt/SwissProt
Match: sp|A0M8S8|MET_FELCA (Hepatocyte growth factor receptor OS=Felis catus OX=9685 GN=MET PE=3 SV=1)

HSP 1 Score: 120.553 bits (301), Expect = 2.544e-26
Identity = 86/268 (32.09%), Postives = 137/268 (51.12%), Query Frame = 3

Query: 1803 IGRGNFSTVFKAKYSRSKDNAIPVAAKWLNDKND-KTLNKIKTE-LFPSTFPHKNVLKSYGYCILKDQTYLI--SELAFQDLLRYLQS-NQLPNDRTCINFCLQVCQGMKFLSDDRKFIHRDLAARNILVFKDKDENVTLKISDFGLTIKLMNKNYYN-SNSQGNFF---WLPDDEFKTGKFTVKTDIYSYGVVMWEIFSGGKD----------VVKMRKSHRTLPKEFDDIKILDGAYNLMKGCWSV-GDLQPNDFNSLIHLLKALL 2546
            IGRG+F  V+      S D  I  A K LN   D   +++  TE +    F H NVL   G C+  + + L+    +   DL  ++++    P  +  I F LQV +GMK+L+  +KF+HRDLAARN ++    DE  T+K++DFGL   + +K YY+  N  G      W+  +  +T KFT K+D++S+GV++WE+ + G             V + +  R L  E+      D  Y +M  CW    +L+P+ F+ L+  + A+ 
Sbjct: 1085 IGRGHFGCVYHGTLLDSDDKKIHCAVKSLNRITDIGEVSQFLTEGIIMKDFSHPNVLSLLGICLRSEGSPLVVLPYMKHGDLRNFIRNETHNPTVKDLIGFGLQVAKGMKYLAS-KKFVHRDLAARNCML----DEKFTVKVADFGLARDMYDKEYYSVHNKTGAKLPVKWMALESLQTQKFTTKSDVWSFGVLLWELMTRGAPPYPDVNTFDITVYLLQGRRLLQPEY----CPDPLYEVMLKCWHPKAELRPS-FSELVSRISAIF 1342

[Close]

BLAST of Hepatocyte growth factor receptor vs. TrEMBL
Match: A0A336MEA8 (Tyrosine-protein kinase receptor OS=Culicoides sonorensis OX=179676 GN=CSON000362 PE=3 SV=1)

HSP 1 Score: 128.257 bits (321), Expect = 1.964e-26
Identity = 93/288 (32.29%), Postives = 154/288 (53.47%), Query Frame = 3

Query: 1737 RDAKIFQLNEIKPEELQIEKTPIGRGNFSTVFKAKYSRSKDNAIPVAAKWLND-KNDKTLNKIKTEL-FPSTFPHKNVLKSYGYCILKDQTY--LISELAFQDLLRYLQSNQLPNDRTCIN------FCLQVCQGMKFLSDDRKFIHRDLAARNILVFKDKDENVTLKISDFGLTIKLMNKNYYNSNSQG--NFFWLPDDEFKTGKFTVKTDIYSYGVVMWEIFSGG---------KDVVKMRKSHRTLPKEFDDIKILDGAYNLMKGCWSVGDLQPNDFNSLIHLLK 2537
            ++A I ++ + K ++++  +  +G G F  V+K + +  + + I VA K L +  + KT    K E+   S   H+N++   G  ILK + Y  L   ++  DL  +L +N  PN+   ++        LQ+C GM +L++   ++HRDLAARN LV     EN+T+KISDFGL+  + + +YY   S+      W+P +    GKFT ++D++SYGVV+WEI+S G         ++V+ M ++ + LP         +  YNLMK CW    ++   F  + H LK
Sbjct:  487 QNAAILRVPQYKLDDVKFVEE-LGEGAFGKVYKGELTTKEKDKIFVAVKALKENASAKTQQDFKREIELISDLHHENIVNILG-VILKKEPYCMLFEFMSEGDLHEFLITNS-PNEGKSLSQMQFLYIALQICDGMTYLANHH-YVHRDLAARNCLV----GENLTVKISDFGLSRDIYSSDYYRVQSKSLLPVRWMPSESILYGKFTTESDVWSYGVVLWEIYSYGLQPYYGYSNQEVINMIRARQLLPCPES---CPEYVYNLMKACWDEQAVRRPAFPEIGHRLK 763

[Close]

BLAST of Hepatocyte growth factor receptor vs. TrEMBL
Match: A0A336LGT4 (Tyrosine-protein kinase receptor OS=Culicoides sonorensis OX=179676 GN=CSON007949 PE=3 SV=1)

HSP 1 Score: 127.872 bits (320), Expect = 2.503e-26
Identity = 93/288 (32.29%), Postives = 154/288 (53.47%), Query Frame = 3

Query: 1737 RDAKIFQLNEIKPEELQIEKTPIGRGNFSTVFKAKYSRSKDNAIPVAAKWLND-KNDKTLNKIKTEL-FPSTFPHKNVLKSYGYCILKDQTY--LISELAFQDLLRYLQSNQLPNDRTCIN------FCLQVCQGMKFLSDDRKFIHRDLAARNILVFKDKDENVTLKISDFGLTIKLMNKNYYNSNSQG--NFFWLPDDEFKTGKFTVKTDIYSYGVVMWEIFSGG---------KDVVKMRKSHRTLPKEFDDIKILDGAYNLMKGCWSVGDLQPNDFNSLIHLLK 2537
            ++A I ++ + K ++++  +  +G G F  V+K + +  + + I VA K L +  + KT    K E+   S   H+N++   G  ILK + Y  L   ++  DL  +L +N  PN+   ++        LQ+C GM +L++   ++HRDLAARN LV     EN+T+KISDFGL+  + + +YY   S+      W+P +    GKFT ++D++SYGVV+WEI+S G         ++V+ M ++ + LP         +  YNLMK CW    ++   F  + H LK
Sbjct:  487 QNAAILRVPQYKLDDVKFVEE-LGEGAFGKVYKGELTTKEKDKIFVAVKALKENASAKTQQDFKREIELISDLHHENIVNILG-VILKKEPYCMLFEFMSEGDLHEFLITNS-PNEGKSLSQMQFLYIALQICDGMTYLANHH-YVHRDLAARNCLV----GENLTVKISDFGLSRDIYSSDYYRVQSKSLLPVRWMPSESILYGKFTTESDVWSYGVVLWEIYSYGLQPYYGYSNQEVINMIRARQLLPCPES---CPEYVYNLMKACWDEQAVRRPAFPEIGHRLK 763

[Close]

BLAST of Hepatocyte growth factor receptor vs. TrEMBL
Match: A0A0J7K479 (Tyrosine-protein kinase receptor OS=Lasius niger OX=67767 GN=RF55_16282 PE=3 SV=1)

HSP 1 Score: 120.553 bits (301), Expect = 6.885e-26
Identity = 99/310 (31.94%), Postives = 146/310 (47.10%), Query Frame = 3

Query: 1689 VQKDNIFIPKCIEIYNRDAKIFQLNEIKPEELQIEKTPIGRGNFSTVFKAKYSRSKDNAI--PVAAKWLNDKNDKTLNK---IKTELFPSTFPHKNVLKSYGYCILKDQTYLISELA-FQDLLRYLQSNQ--LPNDRTCINF------CLQVCQGMKFLSDDRKFIHRDLAARNILVFKDKDENVTLKISDFGLTIKLMNKNYYNSNSQG--NFFWLPDDEFKTGKFTVKTDIYSYGVVMWEIFSGGKDVVKMRKSHRT---------LPKEFDDIKILDGAYNLMKGCWSVGDLQPNDFNSLIHLLKAL 2543
            VQ + ++ P   E YN D   F L +IK E++++ K  +G G F  VF+      +   I  P A K L  KN  +  K   ++     + F HK+VL+    C+ KD   L+ EL    DLL+YL+ ++   P+D   +        C  V +G  +L   R F+HRDLA RN LV      N  +KI DFGL   +   +YY    +      W+  +    G FT ++D++S+GV+MWEI S G      + +H           LPK  +    L   Y LM  CWS  + +PN FN  +  + AL
Sbjct:   17 VQFNTLYSPTLPE-YNPDE--FVLTKIKREQIRLAKL-LGSGAFGMVFQGNVKDLEGPGIETPAAIKMLR-KNASSQEKKKFLQEARLMNHFRHKHVLRLLAVCLNKDSPLLVLELMEIGDLLKYLRESRKLQPSDSHALRLQDLLAMCEDVARGCSYLEKLR-FVHRDLACRNCLVSARDRANRVVKIGDFGLARDVYKDDYYRKEEESLLPIRWMAPESLVIGIFTSQSDVWSFGVLMWEITSLGNQPYTAKANHEVLNYVRAGGRLPKPLNCPSTL---YKLMLRCWSAENARPN-FNLCLENIIAL 316

[Close]

BLAST of Hepatocyte growth factor receptor vs. TrEMBL
Match: A0A1S3JTZ5 (Tyrosine-protein kinase OS=Lingula unguis OX=7574 GN=LOC106176113 PE=3 SV=1)

HSP 1 Score: 124.79 bits (312), Expect = 1.167e-25
Identity = 95/279 (34.05%), Postives = 150/279 (53.76%), Query Frame = 3

Query: 1764 EIKPEELQIEKTPIGRGNFSTVFKAKYSRSKDNAIPVAAKWLNDKNDKTLNKIKTELFPSTFPHKNVLKSYGYCILKDQTYLISE-LAFQDLLRYLQSNQ---LPNDRT--CINFCLQVCQGMKFLSDDRKFIHRDLAARNILVFKDKDENVTLKISDFGLTIKLMNKNYYNSNSQGNFF---WLPDDEFKTGKFTVKTDIYSYGVVMWEIFSGGKDVVKMRKSHRTLPKEFDDIKILD--GA-----YNLMKGCWSV-GDLQPNDFNSLIHLLKALLE 2549
            EI   ELQ+    +GRG F TVFKAK+      AI VA K ++       + I+         H N+++ YG C  +   Y+++E +    LL YL+ ++   L +++    ++ CLQVC+ M +L +++ FIHRDLAARN LV    +ENV +K++DFGL   +++  Y  ++S G  F   W P +     +F+ K+D++S+G++MWEIF+GG D+   R  +  + +     K LD  GA     Y  M  CW    D +P  F  + + L  L+E
Sbjct:  361 EIDSSELQL-GLELGRGQFGTVFKAKWR----GAIEVAVKMMHQGTMSEDDFIEEARTMKQLQHPNLVQLYGVCTKRRPIYIVTEFMKHGSLLNYLRRHKHRLLQSNKAGLLLDMCLQVCKAMAYL-EEQSFIHRDLAARNCLV---GEENV-VKVADFGLARYVLDDEY--TSSSGTKFPIKWAPPEVLCYTRFSSKSDVWSFGILMWEIFTGG-DMPYGRMRNAEVAEFIQKNKRLDKPGACPSIIYEQMYSCWHREADRRPR-FQEIQNELSKLVE 625

[Close]

BLAST of Hepatocyte growth factor receptor vs. TrEMBL
Match: A0A1S3JUM6 (Tyrosine-protein kinase OS=Lingula unguis OX=7574 GN=LOC106176113 PE=3 SV=1)

HSP 1 Score: 124.405 bits (311), Expect = 1.205e-25
Identity = 95/279 (34.05%), Postives = 150/279 (53.76%), Query Frame = 3

Query: 1764 EIKPEELQIEKTPIGRGNFSTVFKAKYSRSKDNAIPVAAKWLNDKNDKTLNKIKTELFPSTFPHKNVLKSYGYCILKDQTYLISE-LAFQDLLRYLQSNQ---LPNDRT--CINFCLQVCQGMKFLSDDRKFIHRDLAARNILVFKDKDENVTLKISDFGLTIKLMNKNYYNSNSQGNFF---WLPDDEFKTGKFTVKTDIYSYGVVMWEIFSGGKDVVKMRKSHRTLPKEFDDIKILD--GA-----YNLMKGCWSV-GDLQPNDFNSLIHLLKALLE 2549
            EI   ELQ+    +GRG F TVFKAK+      AI VA K ++       + I+         H N+++ YG C  +   Y+++E +    LL YL+ ++   L +++    ++ CLQVC+ M +L +++ FIHRDLAARN LV    +ENV +K++DFGL   +++  Y  ++S G  F   W P +     +F+ K+D++S+G++MWEIF+GG D+   R  +  + +     K LD  GA     Y  M  CW    D +P  F  + + L  L+E
Sbjct:  365 EIDSSELQL-GLELGRGQFGTVFKAKWR----GAIEVAVKMMHQGTMSEDDFIEEARTMKQLQHPNLVQLYGVCTKRRPIYIVTEFMKHGSLLNYLRRHKHRLLQSNKAGLLLDMCLQVCKAMAYL-EEQSFIHRDLAARNCLV---GEENV-VKVADFGLARYVLDDEY--TSSSGTKFPIKWAPPEVLCYTRFSSKSDVWSFGILMWEIFTGG-DMPYGRMRNAEVAEFIQKNKRLDKPGACPSIIYEQMYSCWHREADRRPR-FQEIQNELSKLVE 629

[Close]

BLAST of Hepatocyte growth factor receptor vs. Ensembl Cavefish
Match: met (MET proto-oncogene, receptor tyrosine kinase [Source:ZFIN;Acc:ZDB-GENE-041014-1])

HSP 1 Score: 117.087 bits (292), Expect = 3.193e-26
Identity = 79/266 (29.70%), Postives = 130/266 (48.87%), Query Frame = 3

Query: 1803 IGRGNFSTVFKAKYSRSKDNAIPVAAKWLNDKND--KTLNKIKTELFPSTFPHKNVLKSYGYCILKDQTYLI--SELAFQDLLRYLQ-SNQLPNDRTCINFCLQVCQGMKFLSDDRKFIHRDLAARNILVFKDKDENVTLKISDFGLTIKLMNKNYYNSNSQGNFF----WLPDDEFKTGKFTVKTDIYSYGVVMWEIFSGGKD----------VVKMRKSHRTLPKEFDDIKILDGAYNLMKGCWSVGDLQPNDFNSLIHLLKAL 2543
            IGRG+F  VF              A K LN   D  +    +K  +    F H NVL   G C+  + + L+    +   DL  +++     P  +  + F LQV +GM++L+  +KF+HRDLAARN ++    DE+ T+K++DFGL   + +K YY+ +++        W+  +  +T KFT K+D++S+GV++WE+ + G             V + +  R L  EF      D  YN+M  CW     +   F+ L+  + A+
Sbjct: 1055 IGRGHFGCVFHGTLLEPDGQKQHCAVKSLNRITDIEEVSQFLKEGIIMKDFSHPNVLSLLGICLPSEGSPLVVLPYMKHGDLRNFIRDETHNPTVKDLMGFGLQVAKGMEYLAS-KKFVHRDLAARNCML----DESYTVKVADFGLARDVYDKEYYSVHNKSGVKLPVKWMALESLQTHKFTTKSDVWSFGVLLWELMTRGAPPYSDVNSFDITVFLLQGRRLLQPEF----CPDALYNVMIECWHPKPERRPTFSELVSRISAI 1311

[Close]

BLAST of Hepatocyte growth factor receptor vs. Ensembl Cavefish
Match: met (MET proto-oncogene, receptor tyrosine kinase [Source:ZFIN;Acc:ZDB-GENE-041014-1])

HSP 1 Score: 107.071 bits (266), Expect = 1.988e-25
Identity = 68/227 (29.96%), Postives = 117/227 (51.54%), Query Frame = 3

Query: 1947 FPHKNVLKSYGYCILKDQTYLI--SELAFQDLLRYLQ-SNQLPNDRTCINFCLQVCQGMKFLSDDRKFIHRDLAARNILVFKDKDENVTLKISDFGLTIKLMNKNYYNSNSQGNFF----WLPDDEFKTGKFTVKTDIYSYGVVMWEIFSGGKD----------VVKMRKSHRTLPKEFDDIKILDGAYNLMKGCWSVGDLQPNDFNSLIHLLKALLE*TSVNVFVL 2576
            F H NVL   G C+  + + L+    +   DL  +++     P  +  + F LQV +GM++L+  +KF+HRDLAARN ++    DE+ T+K++DFGL   + +K YY+ +++        W+  +  +T KFT K+D++S+GV++WE+ + G             V + +  R L  EF      D  YN+M  CW     +   F+ L+  + A+    S   ++L
Sbjct:    4 FSHPNVLSLLGICLPSEGSPLVVLPYMKHGDLRNFIRDETHNPTVKDLMGFGLQVAKGMEYLAS-KKFVHRDLAARNCML----DESYTVKVADFGLARDVYDKEYYSVHNKSGVKLPVKWMALESLQTHKFTTKSDVWSFGVLLWELMTRGAPPYSDVNSFDITVFLLQGRRLLQPEF----CPDALYNVMIECWHPKPERRPTFSELVSRISAIFSSFSGEHYIL 221

[Close]

BLAST of Hepatocyte growth factor receptor vs. Ensembl Cavefish
Match: btk (Bruton agammaglobulinemia tyrosine kinase [Source:ZFIN;Acc:ZDB-GENE-070531-1])

HSP 1 Score: 112.464 bits (280), Expect = 2.249e-25
Identity = 86/285 (30.18%), Postives = 146/285 (51.23%), Query Frame = 3

Query: 1752 FQLNEIKPEELQIEKTPIGRGNFSTVFKAKYSRSKDNAIPVAAKWLNDKND-----KTLNKIKTELFPSTFPHKNVLKSYGYCILKDQTYLISE-LAFQDLLRYLQSN-QLPNDRTCINFCLQVCQGMKFLSDDRKFIHRDLAARNILVFKDKDENVTLKISDFGLTIKLMNKNYYNS-NSQGNFFWLPDDEFKTGKFTVKTDIYSYGVVMWEIFSGGKD----------VVKMRKSHRTLPKEFDDIKILDGAYNLMKGCWS-VGDLQPNDFNSLIHLLKALLE 2549
            + + EI P +L   K  +G G F  V   K+    D AI +  +    ++D     K + K++         H+N+++ YG C  +   Y+++E L    LL YL+   Q P+    +  C  V +GM +L + +++IHRDLAARN LV    D N T+K++DFGL+  +++  Y +S  S+    W P +     KF+ K+DI+++GV+MWEI++ G+           V K+   HR    +  + +I    Y++M  CW    D +P  F  L+ +++ L+E
Sbjct:  315 YGVWEIDPRQLTFIKE-LGNGQFGVVKYGKWQGRHDVAIKMIKEGSMSEDDFIEEAKVMMKLR---------HENLVQLYGVCTKQRPIYIVTEFLPNGCLLTYLRDYLQHPSPLLLLEMCKDVTEGMAYL-ESQQYIHRDLAARNCLV----DSNGTVKVTDFGLSRYVLDDEYTSSVGSKFPVRWSPPEVLLYSKFSSKSDIWAFGVLMWEIYTLGRMPYDRMNNTEIVEKVSGGHRLYRPQLANDRI----YSVMTSCWHDKADERPT-FQDLVMIIQDLVE 579

[Close]

BLAST of Hepatocyte growth factor receptor vs. Ensembl Cavefish
Match: btk (Bruton agammaglobulinemia tyrosine kinase [Source:ZFIN;Acc:ZDB-GENE-070531-1])

HSP 1 Score: 112.464 bits (280), Expect = 2.518e-25
Identity = 86/281 (30.60%), Postives = 144/281 (51.25%), Query Frame = 3

Query: 1764 EIKPEELQIEKTPIGRGNFSTVFKAKYSRSKDNAIPVAAKWLNDKND-----KTLNKIKTELFPSTFPHKNVLKSYGYCILKDQTYLISE-LAFQDLLRYLQSN-QLPNDRTCINFCLQVCQGMKFLSDDRKFIHRDLAARNILVFKDKDENVTLKISDFGLTIKLMNKNYYNS-NSQGNFFWLPDDEFKTGKFTVKTDIYSYGVVMWEIFSGGKD----------VVKMRKSHRTLPKEFDDIKILDGAYNLMKGCWS-VGDLQPNDFNSLIHLLKALLE 2549
            EI P +L   K  +G G F  V   K+    D AI +  +    ++D     K + K++         H+N+++ YG C  +   Y+++E L    LL YL+   Q P+    +  C  V +GM +L + +++IHRDLAARN LV    D N T+K++DFGL+  +++  Y +S  S+    W P +     KF+ K+DI+++GV+MWEI++ G+           V K+   HR    +  + +I    Y++M  CW    D +P  F  L+ +++ L+E
Sbjct:  338 EIDPRQLTFIKE-LGNGQFGVVKYGKWQGRHDVAIKMIKEGSMSEDDFIEEAKVMMKLR---------HENLVQLYGVCTKQRPIYIVTEFLPNGCLLTYLRDYLQHPSPLLLLEMCKDVTEGMAYL-ESQQYIHRDLAARNCLV----DSNGTVKVTDFGLSRYVLDDEYTSSVGSKFPVRWSPPEVLLYSKFSSKSDIWAFGVLMWEIYTLGRMPYDRMNNTEIVEKVSGGHRLYRPQLANDRI----YSVMTSCWHDKADERPT-FQDLVMIIQDLVE 598

[Close]

BLAST of Hepatocyte growth factor receptor vs. Ensembl Cavefish
Match: mst1rb (macrophage stimulating 1 receptor [Source:NCBI gene;Acc:103041797])

HSP 1 Score: 111.309 bits (277), Expect = 2.105e-24
Identity = 78/266 (29.32%), Postives = 133/266 (50.00%), Query Frame = 3

Query: 1803 IGRGNFSTVFKAKYSRSKDNAIPVAAKWLNDKND--KTLNKIKTELFPSTFPHKNVLKSYGYCILKDQTYLI--SELAFQDLLRYLQS-NQLPNDRTCINFCLQVCQGMKFLSDDRKFIHRDLAARNILVFKDKDENVTLKISDFGLTIKLMNKNYY----NSNSQGNFFWLPDDEFKTGKFTVKTDIYSYGVVMWEIFSGGK---------DVVKMRKSHRTLPKEFDDIKILDGAYNLMKGCWSVGDLQPNDFNSLIHLLKALL 2546
            IG+G+F TV+    +   +  I  A K LN   D  +    +K  +    F H NVL   G  + ++   L+    +   DL  +++  N+ P  +  I F LQV +GM++L+  +KF+HRDLAARN ++    DE+ T+K++DFG+   + +K YY    +  ++    W+  +  +T KFT K+D++S+GV+MWE+ + G          D+       R LP+        D  + +M  CW     +   F +L+  + A+L
Sbjct: 1073 IGKGHFGTVYHGYLTDHNNREIHCAVKSLNRITDVEEVEQFLKEGILMKGFHHSNVLSLLGVLLPEEGLPLVVLPYMKHGDLRHFIRCENRNPTVKDLIGFGLQVAKGMEYLAM-KKFVHRDLAARNCML----DESYTVKVADFGMARDVFDKEYYSIQDHRKAKLPVKWMAIESLQTQKFTSKSDVWSFGVLMWELLTRGASPYPEVDPYDITHYLLRGRRLPQP---QYCPDPLFAVMLQCWDPDPERRPSFTTLVSEVMAIL 1330

[Close]

BLAST of Hepatocyte growth factor receptor vs. Ensembl Sea Lamprey
Match: ENSPMAT00000009736.1 (pep scaffold:Pmarinus_7.0:GL479388:5844:12989:-1 gene:ENSPMAG00000008798.1 transcript:ENSPMAT00000009736.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 103.605 bits (257), Expect = 4.767e-25
Identity = 70/225 (31.11%), Postives = 114/225 (50.67%), Query Frame = 3

Query: 1920 IKTELFPSTFPHKNVLKSYGYCILKDQTYLI--SELAFQDLLRYL-QSNQLPNDRTCINFCLQVCQGMKFLSDDRKFIHRDLAARNILVFKDKDENVTLKISDFGLTIKLMNKNYY----NSNSQGNFFWLPDDEFKTGKFTVKTDIYSYGVVMWEIFSGGK---------DVVKMRKSHRTLPK-EFDDIKILDGAYNLMKGCWSVGDLQPNDFNSLIHLLKAL 2543
            ++  L    F H+NVL   G C+    T L+    +   DL  +L Q    P  +  I F LQV +GM++L+  +KF+HRDLAARN ++    DE+ T+K++DFGL   + NK YY    +  ++    W+  +  +T +FT K+D++S+GV++WE+ + G          D+ +  +  R LP+ E+      D  +  M  CW         F  L+  L+ L
Sbjct:   11 LREGLLMKNFQHENVLSLLGICMPLHGTPLVVLPYMKHGDLGHFLRQETHNPTVKDLIGFGLQVARGMEYLAS-KKFVHRDLAARNCML----DESYTVKVADFGLARDIYNKEYYSIRNHQRAKLPIKWIALESLQTQRFTTKSDVWSFGVLLWELQTRGAPPYPDVDPFDMARFLRQGRRLPQPEY----CPDELFERMLDCWGPTAGDRPGFPELVRRLELL 226

[Close]

BLAST of Hepatocyte growth factor receptor vs. Ensembl Sea Lamprey
Match: frk (fyn-related Src family tyrosine kinase [Source:ZFIN;Acc:ZDB-GENE-110411-7])

HSP 1 Score: 101.679 bits (252), Expect = 2.839e-23
Identity = 78/281 (27.76%), Postives = 141/281 (50.18%), Query Frame = 3

Query: 1764 EIKPEELQIEKTPIGRGNFSTVFKAKYSRSKDNAIPVAAKWLNDKNDKTLNKIKTELFPSTFPHKNVLKSYGYCILKDQTYLISELAFQ-DLLRYLQSNQLPNDRTC--INFCLQVCQGMKFLSDDRKFIHRDLAARNILVFKDKDENVTLKISDFGLTIKLMNKNYYNSNSQGNFF--WLPDDEFKTGKFTVKTDIYSYGVVMWEIFSGGK---------DVV-KMRKSHRT-----LPKEFDDIKILDGAYNLMKGCWSVGDLQPNDFNSLIHLLKALL 2546
            E+K   +++ +  +G G F  V++  ++++      VA K L          +        F H N+++ Y  C  ++  Y+I+EL     LL+YLQ+++    + C  IN  +QV  GM +L + + +IHRDLAARNILV     +N+T K++DFGL  +++  + Y +   G F   W   +     +FT+K+D++S+G++++EI + GK         +V+ ++   +R       P++F         Y++M  CW   +     F  L H L+ L+
Sbjct:  117 EVKRSSIELLRQ-LGAGQFGEVYEGLWNKTTR----VAVKTLKPGAMVPEEFLAEAHIMKRFTHCNLIQLYAVCTTEEPIYIITELMVNGSLLQYLQNDEGGVLKMCHLINMAVQVASGMAYL-EAQNYIHRDLAARNILV----GDNLTCKVADFGLA-RVIKDDEYIAREGGKFPVKWTAPEAANYSRFTIKSDVWSFGILLYEIVTYGKVPYAGMTNAEVLEELEHGYRMPCPTNCPRDF---------YSIMYNCWHKEEACRPSFLQLDHQLEDLI 377

[Close]

BLAST of Hepatocyte growth factor receptor vs. Ensembl Sea Lamprey
Match: ENSPMAT00000004129.1 (pep scaffold:Pmarinus_7.0:GL490249:304:4500:1 gene:ENSPMAG00000003774.1 transcript:ENSPMAT00000004129.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 98.5969 bits (244), Expect = 6.056e-23
Identity = 75/238 (31.51%), Postives = 128/238 (53.78%), Query Frame = 3

Query: 1803 IGRGNFSTVFKAKYSRSKDNAIPVAAKWLNDKNDKTLNKIKTELFPSTFPHKNVLKSYGYCILKDQTYLISELA-FQDLLRYLQ--SNQLPN-DRTCINFCLQVCQGMKFLSDDRKFIHRDLAARNILVFKDKDENVTLKISDFGLTIKLMNKNYYNSNSQGNFFWLPDDEFKTGKFTVKTDIYSYGVVMWEIFSGGK-DVVKMRKSH-RTLPKEFDDIKILDGA----YNLMKGCWS 2486
            +GRGNF  V++ +++ + D AI +     N   D  + ++KT +   +F H+NVL+ Y  C  K   ++++EL  + ++L YL    ++L   +R  + F   +  GM +LS  R  IH DLA RNIL+     ++   K++DFGL+ KL  + Y  +     F W+  +     KFT K+D++S+GV+++E+F+ GK     M K   + L K    +K  D      Y++M+ CW+
Sbjct:   29 LGRGNFGEVYEGRWNDTTDVAIKIVRT--NSSFDTFMKEVKTMI---SFKHENVLQIYAVCKEKWPYWIVTELVPYGNMLHYLGRFGHELSEVERLYMAF--GIASGMAYLSKKR-CIHCDLAGRNILM----GQHNICKVADFGLSHKLKEEYYDATGHVVPFQWMAPEVLIQLKFTRKSDVWSFGVLLYELFTDGKRPYADMDKQQVQDLIKCGGRLKRPDACPNVVYHIMQRCWN 254

[Close]

BLAST of Hepatocyte growth factor receptor vs. Ensembl Sea Lamprey
Match: txk (TXK tyrosine kinase [Source:ZFIN;Acc:ZDB-GENE-130530-553])

HSP 1 Score: 100.523 bits (249), Expect = 6.168e-23
Identity = 74/275 (26.91%), Postives = 129/275 (46.91%), Query Frame = 3

Query: 1752 FQLNEIKPEELQIEKTPIGRGNFSTVFKAKYSRSKDNAIPVAAKWLNDKNDKTLNKIKTELFPSTFPHKNVLKSYGYCILKDQTYLISE-LAFQDLLRYLQSNQLPN-DRTCINFCLQVCQGMKFLSDDRKFIHRDLAARNILVFKDKDENVTLKISDFGLTIKLMNKNYYNSNSQGNFF---WLPDDEFKTGKFTVKTDIYSYGVVMWEIFSGGKDVVKMRKSHRTLPKEFDDIKILD------GAYNLMKGCWSVGDLQPNDFNSLIHLLKAL 2543
            +Q  EI P+EL      +G G +  V   ++ R K     VA K + +      + I+         H  +++ YG C  +    +++E +    LL +L+S +           CL VC+ M +L +++ F+HRDLAARN LV     E   +K+SDFG+T      +   + S G  F   W P + F+  +F+ K+D++S+GV+MWE+++ G    +   + + + +     ++         AYN+M  CW         F  L+  ++AL
Sbjct:  109 YQKWEIDPQELTFTHE-LGSGQYGVVRLGQWKRQKL----VAVKMIQEGAMSEEDFIEEAKVMMQLSHPRLVQLYGVCTQQRPLCIVTEYMVGGSLLSFLKSQRGSTVPELMAEICLDVCEAMSYL-EEKMFLHRDLAARNCLV----GEGNIVKVSDFGMTSHRYVLDDQYTCSMGAKFPVKWSPPEVFQYTRFSTKSDVWSFGVLMWEVYTEGHMPFEGWSNQQVVDEILRGCRLYQPALSPPTAYNIMLDCWQEKPESRCSFIELLPRIRAL 373

[Close]

BLAST of Hepatocyte growth factor receptor vs. Ensembl Sea Lamprey
Match: ENSPMAT00000001705.1 (pep scaffold:Pmarinus_7.0:GL487204:7598:9057:-1 gene:ENSPMAG00000001543.1 transcript:ENSPMAT00000001705.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 97.4413 bits (241), Expect = 6.916e-23
Identity = 72/232 (31.03%), Postives = 106/232 (45.69%), Query Frame = 3

Query: 1941 STFPHKNVLKSYGYCILKDQTYLISE-LAFQDLLRYLQ--------------------SNQLPNDRTCIN---FCLQVCQGMKFLSDDRKFIHRDLAARNILVFKDKDENVTLKISDFGLTIKLMNKNYY--NSNSQGNFFWLPDDEFKTGKFTVKTDIYSYGVVMWEIFSGGKDVVKMRKSHRTLPKEFDDIKIL---DGA----YNLMKGCWSVGDLQPNDFNSLIHLLK 2537
            + F H N++K  G C +     L+ E +   DL  YL+                    S   P    C +      QV  GM +L++ RKF+HRDLA RN LV       + +KISDFGL+  +   +YY  N N      W+P +     ++T ++D++++GVV+WEIFS G        SH  +     D  +L   DG     YNLM+ CW+        F S+ H+L 
Sbjct:   16 AEFTHPNIVKLLGVCAVGKPFCLLFEFMPHGDLNEYLRRCSSEAGLAASSPPARAPTSSGSEPVSLCCADKLFVATQVAAGMAYLAE-RKFVHRDLATRNCLV----GNRLVVKISDFGLSQSIYAADYYKANENDAIPIRWMPPESIFYNRYTSESDVWAFGVVLWEIFSHGLQPY-FGMSHEEVIYFVRDGNVLACPDGCPLDLYNLMRLCWAHAPADRPSFASVQHVLA 241

[Close]

BLAST of Hepatocyte growth factor receptor vs. Ensembl Yeast
Match: STE11 (Signal transducing MEK kinase; involved in pheromone response and pseudohyphal/invasive growth pathways where it phosphorylates Ste7p, and the high osmolarity response pathway, via phosphorylation of Pbs2p; regulated by Ste20p and Ste50p; protein abundance increases in response to DNA replication stress [Source:SGD;Acc:S000004354])

HSP 1 Score: 63.929 bits (154), Expect = 6.932e-11
Identity = 46/146 (31.51%), Postives = 73/146 (50.00%), Query Frame = 3

Query: 1953 HKNVLKSYGYCILKDQTYLISELAFQDLLRYLQSNQLPNDRTCI-NFCLQVCQGMKFLSDDRKFIHRDLAARNILVFKDKDENVTLKISDFGLTIKL--MNKNYYNSNS-QGNFFWLPDDEFKTGKFTVKTDIYSYGVVMWEIFSG 2378
            H+N++  YG         +  E      +  + +N  P + + I NF  Q+  G+ +L   +  IHRD+   NIL+    D    +KI+DFG++ KL  +NK      S QG+ FW+  +  K    T K DI+S G V+ E+F+G
Sbjct:  513 HENIVTYYGASQEGGNLNIFLEYVPGGSVSSMLNNYGPFEESLITNFTRQILIGVAYLHK-KNIIHRDIKGANILI----DIKGCVKITDFGISKKLSPLNKKQNKRASLQGSVFWMSPEVVKQTATTAKADIWSTGCVVIEMFTG 653

[Close]

BLAST of Hepatocyte growth factor receptor vs. Ensembl Yeast
Match: CLA4 (Cdc42p-activated signal transducing kinase; member of the PAK (p21-activated kinase) family, along with Ste20p and Skm1p; involved in septin ring assembly, vacuole inheritance, cytokinesis, sterol uptake regulation; phosphorylates Cdc3p and Cdc10p; CLA4 has a paralog, SKM1, that arose from the whole genome duplication [Source:SGD;Acc:S000005242])

HSP 1 Score: 63.1586 bits (152), Expect = 1.253e-10
Identity = 30/94 (31.91%), Postives = 52/94 (55.32%), Query Frame = 3

Query: 2097 QVCQGMKFLSDDRKFIHRDLAARNILVFKDKDENVTLKISDFGLTIKLMNKNYYNSNSQGNFFWLPDDEFKTGKFTVKTDIYSYGVVMWEIFSG 2378
            + CQG+KFL  D+  IHRD+ + N+L+    D    +KI+DFG   +L +K    +   G  +W+  +  K  ++  K D++S G++  E+  G
Sbjct:  676 ETCQGLKFL-HDKHIIHRDIKSDNVLL----DTRARVKITDFGFCARLTDKRSKRATMVGTPYWMAPEVVKQREYDEKIDVWSLGIMTIEMLEG 764

[Close]

BLAST of Hepatocyte growth factor receptor vs. Ensembl Yeast
Match: PHO85 (Cyclin-dependent kinase; has ten cyclin partners; involved in regulating the cellular response to nutrient levels and environmental conditions and progression through the cell cycle; human lissencephaly-associated homolog CDK5 functionally complements null mutation [Source:SGD;Acc:S000005952])

HSP 1 Score: 60.4622 bits (145), Expect = 2.810e-10
Identity = 53/207 (25.60%), Postives = 97/207 (46.86%), Query Frame = 3

Query: 1785 QIEKTPIGRGNFSTVFKAKYSRSKDNAIPVAAKW--LNDKNDKTLNKIKTELFPSTFPHKNVLKSYGYCILKDQTYLISELAFQDLLRYLQSNQLPNDRTCIN------FCLQVCQGMKFLSDDRKFIHRDLAARNILVFKDKDENVTLKISDFGLTIKL-MNKNYYNSNSQGNFFWLPDDEFKTGKFTVKTDIYSYGVVMWEIFSG 2378
            Q+EK  +G G ++TV+K     +K   + VA K   L+ +       I+         H+N+++ Y     +++  L+ E    DL +Y+ S  + N    +       F  Q+ QG+ F  ++ K +HRDL  +N+L+ K       LK+ DFGL     +  N ++S     ++  PD    +  ++   DI+S G ++ E+ +G
Sbjct:    9 QLEK--LGNGTYATVYKG---LNKTTGVYVALKEVKLDSEEGTPSTAIREISLMKELKHENIVRLYDVIHTENKLTLVFEFMDNDLKKYMDSRTVGNTPRGLELNLVKYFQWQLLQGLAFCHEN-KILHRDLKPQNLLINKRGQ----LKLGDFGLARAFGIPVNTFSSEVVTLWYRAPDVLMGSRTYSTSIDIWSCGCILAEMITG 205

[Close]

BLAST of Hepatocyte growth factor receptor vs. Ensembl Yeast
Match: SPS1 (Putative protein serine/threonine kinase; localizes to the nucleus and cytoplasm; required for efficient spore packaging, prospore membrane development and closure and localization of enzymes involved in spore wall synthesis; interacts with and required for Ssp1p phosphorylation and turnover; member of the GCKIII subfamily of STE20 kinases; multiply phosphorylated on S/T residues; interacts with 14-3-3 proteins, Bmh1p and Bmh2p; expressed at the end of meiosis [Source:SGD;Acc:S000002931])

HSP 1 Score: 61.2326 bits (147), Expect = 3.466e-10
Identity = 57/211 (27.01%), Postives = 109/211 (51.66%), Query Frame = 3

Query: 1773 PEELQIEKTPIGRGNFSTVFKAKYSRSKDNAIPVAAKWLN-DKNDKTLNKIKTELFPSTFPHKNVLKSYGYCILKDQT-YLISEL----AFQDLLRYLQSNQLPNDRTCINFCL-QVCQGMKFLSDDRKFIHRDLAARNILVFKDKDENVTLKISDFGLTIKLMNKNYYNSNSQGNFFWLPDDEF--KTGKFTVKTDIYSYGVVMWEIFSG 2378
            P +L   ++ IGRGNF  V+KA    +++    VA K +N + +D+ +  +  E+F        ++ +Y   +L+D + +++ E     +  DLL+    N LP ++  ++F + +V  G+K+L + RK IHRD+ A NIL+    +E   +K+ DFG++  + +         G  +W+  +    +   +  K DI+S G+  +E+  G
Sbjct:   14 PSKLYSIQSCIGRGNFGDVYKAVDRVTQEI---VAIKVVNLEHSDEDIELLAQEIFFLAELKSPLITNYIATMLEDVSMWIVMEYCGGGSCSDLLKRSYVNGLPEEK--VSFIIHEVTLGLKYLHEQRK-IHRDIKAANILL----NEEGMVKLGDFGVSGHIRS-TLKRDTFVGTPYWMAPEVVCCEVDGYNEKADIWSLGITTYELLKG 213

[Close]

BLAST of Hepatocyte growth factor receptor vs. Ensembl Yeast
Match: CDC15 (Protein kinase of the Mitotic Exit Network; localized to the spindle pole bodies at late anaphase; promotes mitotic exit by directly switching on the kinase activity of Dbf2p; required for spindle disassembly after meiosis II; relocalizes to the cytoplasm upon DNA replication stress [Source:SGD;Acc:S000000072])

HSP 1 Score: 61.2326 bits (147), Expect = 6.409e-10
Identity = 54/197 (27.41%), Postives = 94/197 (47.72%), Query Frame = 3

Query: 1794 KTPIGRGNFSTVFKAKYSRSKDNAIPVAAKWLNDKNDKTLNKIKTEL-FPSTFPHKNVLKSYGYCILKDQTYLISELAFQDLLRYL--QSNQLPNDRTCINFCLQVCQGMKFLSDDRKFIHRDLAARNILVFKDKDENVTLKISDFGLTIKLMNKNYYNSNSQGNFFWLPDDEFKTGKFTVKTDIYSYGVVMWEIFS 2375
            K  IGRG++  V+KA  ++  D    VA K +  +ND+ LN I  E+       H N++K +G+     + Y++ E      LR L  +S+   ++     +  Q   G+K+L  +   IHRD+ A NIL+  D     T+K++DFG++  +   N       G   W+  +       +  +DI+S G  + E+ +
Sbjct:   28 KQVIGRGSYGVVYKA-INKHTDQV--VAIKEVVYENDEELNDIMAEISLLKNLNHNNIVKYHGFIRKSYELYILLEYCANGSLRRLISRSSTGLSENESKTYVTQTLLGLKYLHGE-GVIHRDIKAANILLSADN----TVKLADFGVSTIV---NSSALTLAGTLNWMAPEILGNRGASTLSDIWSLGATVVEMLT 213

[Close]

BLAST of Hepatocyte growth factor receptor vs. Ensembl Nematostella
Match: EDO49804 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RFY7])

HSP 1 Score: 106.301 bits (264), Expect = 5.831e-26
Identity = 74/222 (33.33%), Postives = 112/222 (50.45%), Query Frame = 3

Query: 1860 NAIPVAAKWLNDKNDKTLNKIKTELFPSTFPHKNVLKSYGYCILKDQTYLISELAFQD-LLRYLQSNQLP-NDRTCINFCLQVCQGMKFLSDDRKFIHRDLAARNILVFKDKDENVTLKISDFGLTIKLMNKNYYNSNSQGNFF---WLPDDEFKTGKFTVKTDIYSYGVVMWEIFSGGK---------DVVKMRKSHRTLPKEFDDIKILDGAYNLMKGCW 2483
              IPVA K + D      + I+       F H N+++ YG C  K   Y+I EL     LL YL+ +Q             QV   MK+L +   FIHRDLAARN L+     EN T+K++DFGL   +++  Y  + S+G  F   W   +     KF+ K+D++++G++ WE+++GGK         DVV+M  +   L K    ++  D AY+ M+ CW
Sbjct:    4 GTIPVAVKMMKDGAMSEEDFIEEAKVMKQFQHGNLVQLYGICSEKP-IYIIQELMKGGCLLHYLRKSQFKLQSAEMTEMVRQVAAAMKYL-ESHNFIHRDLAARNCLI----GENRTVKVADFGLARYVIDDEY--TASEGTKFPIKWAAPEVILYSKFSSKSDVWAFGILAWEVYTGGKQPYPATNNTDVVQMVINGYRLEK---PLRCPDAAYSTMRKCW 214

[Close]

BLAST of Hepatocyte growth factor receptor vs. Ensembl Nematostella
Match: EDO31298 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SYB5])

HSP 1 Score: 107.842 bits (268), Expect = 7.589e-26
Identity = 82/261 (31.42%), Postives = 127/261 (48.66%), Query Frame = 3

Query: 1755 QLNEIKPEELQIEKTPIGRGNFSTVFKAKYSRSKDNAIPVAAKWLNDKNDKTLNKIKTELFPST-----FPHKNVLKSYGYCILKDQTYLISELAFQDLL-RYLQSNQLPNDRTCINFCLQVCQGMKFLSDDRKFIHRDLAARNILVFKDKDENVTLKISDFGLTIKL-MNKNYYNSNSQGNFF--WLPDDEFKTGKFTVKTDIYSYGVVMWEIFS---------GGKDVVKMRKSHRTLPKEFDDIKILDGAYNLMKGCW 2483
            Q  E+K E L + K  +G GNF +V K  Y       IPVA K L   +   +N  K+E+           H  +++  G C       L+ ELA +  L +YL+ N+       +   LQV +GM++L +  +F+HRDLAARN+LV  D      +KISDFG++  +    +YY + + G +   W   +     KF+ K+D++SYG+ +WE  S          G+ +++  +S   LP      K+    Y LMK CW
Sbjct:   17 QTFELKMENLSLGKE-LGHGNFGSVLKGTYKMPNGERIPVAVKSLKSDD---INNPKSEILHEARVMMELDHPYIVRIIGMC-QGPSMMLVMELAGEGPLNKYLKKNKGMPLLNILVLMLQVAEGMQYL-ESLQFVHRDLAARNVLVVNDS----FVKISDFGMSRAMGAGSDYYKAGTAGRWPLKWYAPECIYFRKFSSKSDVWSYGITLWEATSYGARPYQSLSGQAILEKIESGYRLPA---PAKLPSCVYQLMKDCW 264

[Close]

BLAST of Hepatocyte growth factor receptor vs. Ensembl Nematostella
Match: EDO49035 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RHT9])

HSP 1 Score: 103.219 bits (256), Expect = 3.887e-24
Identity = 79/279 (28.32%), Postives = 123/279 (44.09%), Query Frame = 3

Query: 1803 IGRGNFSTVFKAKYSRSKD--NAIPVAAKWLNDKNDKTLNK---IKTELFPSTFPHKNVLKSYGYCILKDQTYLISELA-FQDLLRYLQSNQLPNDR----------------TCINFCLQVCQGMKFLSDDRKFIHRDLAARNILVFKDKDENVTLKISDFGLTIKLMNKNYYNSNSQGNFF---WLPDDEFKTGKFTVKTDIYSYGVVMWEIFSGGKDVVKMRKSHRTLPKEFDDIKI------LDGAYNLMKGCWSVGDLQPNDFNSLIHLLKALL 2546
            +G G F  V KA     K    ++PVA K + + +  T  +    + +L     PH NV+   G C   D   +I E   + DL  YL+  +   D+                  ++F +Q  +GM  L+   K +HRDLAARNIL+    DE    K+SDFG    +  +++Y   +QG  F   W+  +    G  T K+D++SYGV++WEI + G        S   +    D  ++      LD  Y +M  CW +   +   F  +  LL  +L
Sbjct:   15 LGSGAFGVVMKADAQGIKGCVGSLPVAVKIVKENDSDTARRDLMAELDLLKLIDPHPNVIGLLGCCTRGDPLMVIVEFCQYGDLQSYLRHCRGIEDKYYEQIYMVPEKKLTAKDLLSFGIQAARGMAHLAS-MKVVHRDLAARNILI----DEKSVCKVSDFGFARDIYVEDHYTRKTQGGRFPIKWMAIESLLDGVSTTKSDVWSYGVLLWEIVTLGASPYPGMNSQEVINFLQDGYRMDKPKHCLDELYAVMLDCWQLSAQRRPTFVEISRLLNKML 288

[Close]

BLAST of Hepatocyte growth factor receptor vs. Ensembl Nematostella
Match: EDO39121 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SAX2])

HSP 1 Score: 101.679 bits (252), Expect = 1.968e-23
Identity = 88/297 (29.63%), Postives = 136/297 (45.79%), Query Frame = 3

Query: 1764 EIKPEELQIEKTPIGRGNFSTVFKAKYSRSKD--NAIPVAAKWLN---DKNDKTLNKIKTELFPSTFPHKNVLKSYGYCI-----LKDQTYLISE-LAFQDLLRYLQSNQLPNDRTC---------------INFCLQVCQGMKFLSDDRKFIHRDLAARNILVFKDKDENVTLKISDFGLTIKLMNKNYYNSNSQGNFF--WLPDDEFKTGKFTVKTDIYSYGVVMWEIFSGG---------KDVVKMRKSHRTLPKEFDDIKILDGAYNLMKGCWSVGDLQPNDFNSLIHLLKAL 2543
            E+ P+ L + K  +G GNF  V KA           + VA K L     + DKT    +  L  S  PH +V++  G C      L +   +I E L + DLL YL+ ++   D  C               + F   +  GM FL+ + K +HRDLAARN+LV     E+ T KISD GL  + ++++ Y   S       W+P +    G+ +  +D++SYG+V+WEIF+ G         K + +M +    +PK      + D  Y +M  CW     +   F+ L   ++AL
Sbjct:   22 EVPPQNLSVIKR-LGSGNFGHVDKAMAIGIPGFPGQVTVAVKTLKATAQEKDKTDFLTELNLMKSLRPHPHVVRLIGCCTRQAGELSNHLAIIFEYLPYGDLLGYLRRSRGHEDWYCSGDLRPPSRLVSKDLVKFAWMIADGMAFLAAN-KCVHRDLAARNVLV----GEHNTCKISDLGLA-RDVSQDIYTRTSSARLPVKWMPPESLLYGQSSSASDVWSYGIVLWEIFTIGDSPYPGVKSKGIPRMLREGYRMPKP---PHVGDALYFVMLRCWQEDPDERPTFDELCDNMQAL 308

[Close]

BLAST of Hepatocyte growth factor receptor vs. Ensembl Nematostella
Match: EDO35408 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SLJ9])

HSP 1 Score: 98.9821 bits (245), Expect = 7.085e-23
Identity = 75/277 (27.08%), Postives = 123/277 (44.40%), Query Frame = 3

Query: 1803 IGRGNFSTVFKAKYSRSKDNAIPVAAKWLNDKNDKTLNK---IKTELFPSTFPHKNVLKSYGYCILKDQTYLISELA----FQDLLR--------YLQSNQLPNDRTCINFCLQVCQGMKFLSDDRKFIHRDLAARNILVFKDKDENVTLKISDFGLTIKLMNKNYYNSNSQGNFF--WLPDDEFKTGKFTVKTDIYSYGVVMWEIFSGGKDVVKMRKSHRTLPKEFDDIKILDG------------AYNLMKGCWSVGDLQPNDFNSLIHLLKALL 2546
            IG G F  VF       +D  I  A K + D +D+   K   ++ E+      H NV+   G C ++   Y+I+E        D LR        Y+  N     R  +   L V +GM+ ++  +KF+HRDLAARN+L+     + +T K++DFGL   +  +  Y     G     W+  +  +   +T +TD++S+GV++WEI + G      R  +  +P      K+L G             Y++M+ CW +       F  L  +L  +L
Sbjct:   17 IGEGQFGIVFAGTVKIGEDT-IKAAIKCIKDVDDRYDMKDLKLEMEMMKEIGYHPNVVSLIGTCTIETPLYIITEYVSGGNLLDQLRQSRRTDSKYVNVNSTLTSRDLLRIALDVSRGMRHIAM-KKFVHRDLAARNVLM----TDTLTAKVADFGLARDIYCEGKYVKTGGGRLPIKWMAPEAIRDQVYTTQTDVWSFGVLLWEIVTLG------RSPYPGVPIAMLLEKLLYGYKMPCPSHCSEEVYSVMESCWQLEPSARPGFGELSKILTEML 281

[Close]

BLAST of Hepatocyte growth factor receptor vs. Ensembl Medaka
Match: mst1ra (macrophage-stimulating protein receptor-like [Source:NCBI gene;Acc:101175393])

HSP 1 Score: 118.627 bits (296), Expect = 1.181e-26
Identity = 88/283 (31.10%), Postives = 146/283 (51.59%), Query Frame = 3

Query: 1767 IKPEELQIEKTP-IGRGNFSTVFKAKYSRSKDNAIPVAAKWLNDKND--KTLNKIKTELFPSTFPHKNVLKSYGYCILKDQTYLI--SELAFQDLLRYLQSNQL-PNDRTCINFCLQVCQGMKFLSDDRKFIHRDLAARNILVFKDKDENVTLKISDFGLTIKLMNKNYY----NSNSQGNFFWLPDDEFKTGKFTVKTDIYSYGVVMWEIFSGGK---------DVVKMRKSHRTLPKEFDDIKILDGAYNLMKGCW-SVGDLQPNDFNSLI----HLLKAL 2543
            I  E+L+IE +  IG+G+F TV+      S    I  A K LN   D  +    ++  +    F H N+L   G  +  +   L+    +   D+  +++S Q  P  +  I F LQV +GM++L++ +KF+HRDLAARN ++    DE  T+K++DFG+   + +K YY    +S ++    W+  +  +T KFT K+D++SYG++MWE+ + G          D+       R LP+       L   Y++M  CW  V + +P+ F+SL+    H+L  L
Sbjct: 1055 IPAEKLRIEDSKVIGKGHFGTVYHGYLIDSNRQEIHCAVKSLNRITDLDEVHQFLREGIIMKGFHHTNILSLLGIMLPNEGLPLVVLPYMKHGDVRHFIRSEQRNPTVKDLIGFGLQVARGMEYLAE-KKFVHRDLAARNCML----DETFTVKVADFGMARDVYDKEYYSIQNHSRAKLPVKWMAIESLQTQKFTTKSDVWSYGILMWELLTRGASPYPDVDPYDITHYLLKGRRLPQPQYCPNTL---YSIMLTCWDPVPESRPS-FHSLVTEVNHILSCL 1328

[Close]

BLAST of Hepatocyte growth factor receptor vs. Ensembl Medaka
Match: mst1ra (macrophage-stimulating protein receptor-like [Source:NCBI gene;Acc:101175393])

HSP 1 Score: 118.242 bits (295), Expect = 1.304e-26
Identity = 88/283 (31.10%), Postives = 146/283 (51.59%), Query Frame = 3

Query: 1767 IKPEELQIEKTP-IGRGNFSTVFKAKYSRSKDNAIPVAAKWLNDKND--KTLNKIKTELFPSTFPHKNVLKSYGYCILKDQTYLI--SELAFQDLLRYLQSNQL-PNDRTCINFCLQVCQGMKFLSDDRKFIHRDLAARNILVFKDKDENVTLKISDFGLTIKLMNKNYY----NSNSQGNFFWLPDDEFKTGKFTVKTDIYSYGVVMWEIFSGGK---------DVVKMRKSHRTLPKEFDDIKILDGAYNLMKGCW-SVGDLQPNDFNSLI----HLLKAL 2543
            I  E+L+IE +  IG+G+F TV+      S    I  A K LN   D  +    ++  +    F H N+L   G  +  +   L+    +   D+  +++S Q  P  +  I F LQV +GM++L++ +KF+HRDLAARN ++    DE  T+K++DFG+   + +K YY    +S ++    W+  +  +T KFT K+D++SYG++MWE+ + G          D+       R LP+       L   Y++M  CW  V + +P+ F+SL+    H+L  L
Sbjct: 1026 IPAEKLRIEDSKVIGKGHFGTVYHGYLIDSNRQEIHCAVKSLNRITDLDEVHQFLREGIIMKGFHHTNILSLLGIMLPNEGLPLVVLPYMKHGDVRHFIRSEQRNPTVKDLIGFGLQVARGMEYLAE-KKFVHRDLAARNCML----DETFTVKVADFGMARDVYDKEYYSIQNHSRAKLPVKWMAIESLQTQKFTTKSDVWSYGILMWELLTRGASPYPDVDPYDITHYLLKGRRLPQPQYCPNTL---YSIMLTCWDPVPESRPS-FHSLVTEVNHILSCL 1299

[Close]

BLAST of Hepatocyte growth factor receptor vs. Ensembl Medaka
Match: met (MET proto-oncogene, receptor tyrosine kinase [Source:NCBI gene;Acc:101174570])

HSP 1 Score: 115.546 bits (288), Expect = 9.453e-26
Identity = 83/302 (27.48%), Postives = 142/302 (47.02%), Query Frame = 3

Query: 1728 IYNRDAKIFQLNEIKPEELQIEKTPIGRGNFSTVFKAKYSRSKDNAIPVAAKWLNDKND--KTLNKIKTELFPSTFPHKNVLKSYGYCILKDQTYLI--SELAFQDLLRYLQSN-QLPNDRTCINFCLQVCQGMKFLSDDRKFIHRDLAARNILVFKDKDENVTLKISDFGLTIKLMNKNYYNSNSQGNFF----WLPDDEFKTGKFTVKTDIYSYGVVMWEIFSGGKD----------VVKMRKSHRTLPKEFDDIKILDGAYNLMKGCWSVGDLQPNDFNSLIHLLKALLE*TSVNVFVL 2576
            +  R+  +  LN++           IGRG+F  V+           +  A K LN   D  +    +K  +    F H NVL   G C+  + + L+    +   DL  +++     P  +  + F LQV +GM++L+  +KF+HRDLAARN ++    DE+ T+K++DFGL   + +K YY+ +++        W+  +  +T KFT K+D++S+GV++WE+ + G             V + +  R L  EF      D  Y +M  CW     +   F+ L+  + A+    S   +VL
Sbjct: 1067 VITREQLLLHLNQV-----------IGRGHFGCVYHGTLLEPDGQKLHCAVKSLNRITDLEEVSQFLKEGIIMKDFSHPNVLSLLGICLPPEGSPLVVLPYMKHGDLRNFIRDEVHNPTVKDLMGFGLQVARGMEYLAS-KKFVHRDLAARNCML----DESYTVKVADFGLARDIYDKEYYSVHNKSGVKLPVKWMALESLQTHKFTTKSDVWSFGVLLWELMTRGAPPYSDVNSFDITVFLLQGRRLLQPEF----CPDALYTVMVECWHPKPERRPSFSELVSRISAIFSSFSGEHYVL 1348

[Close]

BLAST of Hepatocyte growth factor receptor vs. Ensembl Medaka
Match: mst1rb (macrophage stimulating 1 receptor [Source:NCBI gene;Acc:101159665])

HSP 1 Score: 114.39 bits (285), Expect = 1.951e-25
Identity = 81/267 (30.34%), Postives = 136/267 (50.94%), Query Frame = 3

Query: 1803 IGRGNFSTVFKAKYSRSKDNAIPVAAKWLNDKND--KTLNKIKTELFPSTFPHKNVLKSYGYCILKDQTYLI--SELAFQDLLRYLQSNQL-PNDRTCINFCLQVCQGMKFLSDDRKFIHRDLAARNILVFKDKDENVTLKISDFGLTIKLMNKNYY----NSNSQGNFFWLPDDEFKTGKFTVKTDIYSYGVVMWEIFSGGK---------DVVKMRKSHRTLPKEFDDIKILDGAYNLMKGCWSV-GDLQPNDFNSLIHLLKALL 2546
            IG+G+F TV+    S S    I  A K LN   D  +    +K  +    F H NVL   G  + ++   L+    +   DL  +++  +  P  +  I F LQV +GM++L+  +KF+HRDLAARN ++    DE+ T+K++DFG+   + +K YY    +  ++    W+  +  +T KFT K+D++S+GV+MWE+ + G          D+       R LP+        D  Y +M  CW    +L+P+ F++L+  +  +L
Sbjct: 1070 IGKGHFGTVYHGYLSDSSSREIHCAVKSLNRITDVEEVEQFLKEGIIMKGFHHTNVLSLLGILLPQEGLPLVVLPYMKHGDLRHFIRCEKRNPTVKDLIGFGLQVAKGMEYLAQ-KKFVHRDLAARNCML----DESYTVKVADFGMARDVFDKEYYSIQDHRKAKLPVKWMAIESLQTQKFTSKSDVWSFGVLMWEMLTRGASPYPDVDPYDITHYLMKGRRLPQP---QYCPDPLYKIMLQCWDPDSELRPS-FSTLVVAVSTIL 1327

[Close]

BLAST of Hepatocyte growth factor receptor vs. Ensembl Medaka
Match: mst1rb (macrophage stimulating 1 receptor [Source:NCBI gene;Acc:101159665])

HSP 1 Score: 114.39 bits (285), Expect = 2.187e-25
Identity = 81/267 (30.34%), Postives = 136/267 (50.94%), Query Frame = 3

Query: 1803 IGRGNFSTVFKAKYSRSKDNAIPVAAKWLNDKND--KTLNKIKTELFPSTFPHKNVLKSYGYCILKDQTYLI--SELAFQDLLRYLQSNQL-PNDRTCINFCLQVCQGMKFLSDDRKFIHRDLAARNILVFKDKDENVTLKISDFGLTIKLMNKNYY----NSNSQGNFFWLPDDEFKTGKFTVKTDIYSYGVVMWEIFSGGK---------DVVKMRKSHRTLPKEFDDIKILDGAYNLMKGCWSV-GDLQPNDFNSLIHLLKALL 2546
            IG+G+F TV+    S S    I  A K LN   D  +    +K  +    F H NVL   G  + ++   L+    +   DL  +++  +  P  +  I F LQV +GM++L+  +KF+HRDLAARN ++    DE+ T+K++DFG+   + +K YY    +  ++    W+  +  +T KFT K+D++S+GV+MWE+ + G          D+       R LP+        D  Y +M  CW    +L+P+ F++L+  +  +L
Sbjct: 1056 IGKGHFGTVYHGYLSDSSSREIHCAVKSLNRITDVEEVEQFLKEGIIMKGFHHTNVLSLLGILLPQEGLPLVVLPYMKHGDLRHFIRCEKRNPTVKDLIGFGLQVAKGMEYLAQ-KKFVHRDLAARNCML----DESYTVKVADFGMARDVFDKEYYSIQDHRKAKLPVKWMAIESLQTQKFTSKSDVWSFGVLMWEMLTRGASPYPDVDPYDITHYLMKGRRLPQP---QYCPDPLYKIMLQCWDPDSELRPS-FSTLVVAVSTIL 1313

[Close]

BLAST of Hepatocyte growth factor receptor vs. Planmine SMEST
Match: SMESG000037119.1 (SMESG000037119.1)

HSP 1 Score: 1472.99 bits (3812), Expect = 0.000e+0
Identity = 728/728 (100.00%), Postives = 728/728 (100.00%), Query Frame = 3

Query:  366 MIEIFPFVIVIYYMLMNNQNKDDVLSFLRNIFRMKDSMKFVILINRMMKNIQNVVTDELMCKSIDELIIKLSKNMITNIYFQTYYSRYLCITVTLNHLQVNNDMFNWNDISNATVTEKEKDFYLKIEMNDLFSDLAIDLPMKNEEEANSVHFILVAQMDLVHYDHCSSVLQSYHPRSCTEQHWSIQRLIRDHQPNRLTISYLSERSTQDYMGDSFLINFIPLSANKYACXXXXXXXXXXXXFWGIWFRYQDWHHPFILKCYGLFKESCGFFRECADGPLFFNVYKNNQDFLFRDVLDVLYSIGSALDYLHRNLGQVHGNVNLKSIVRVGKNFKLSEASISESNSEVLEIAKYFDENLEEGRRRNPCITDVYGLLLSIMLIYFMNEDLKDHKVSQSSFRETKCLLKELILKAFQSQDMAISLLENLYKISVNFTDSTSDEVIVQKDNIFIPKCIEIYNRDAKIFQLNEIKPEELQIEKTPIGRGNFSTVFKAKYSRSKDNAIPVAAKWLNDKNDKTLNKIKTELFPSTFPHKNVLKSYGYCILKDQTYLISELAFQDLLRYLQSNQLPNDRTCINFCLQVCQGMKFLSDDRKFIHRDLAARNILVFKDKDENVTLKISDFGLTIKLMNKNYYNSNSQGNFFWLPDDEFKTGKFTVKTDIYSYGVVMWEIFSGGKDVVKMRKSHRTLPKEFDDIKILDGAYNLMKGCWSVGDLQPNDFNSLIHLLKALLE 2549
            MIEIFPFVIVIYYMLMNNQNKDDVLSFLRNIFRMKDSMKFVILINRMMKNIQNVVTDELMCKSIDELIIKLSKNMITNIYFQTYYSRYLCITVTLNHLQVNNDMFNWNDISNATVTEKEKDFYLKIEMNDLFSDLAIDLPMKNEEEANSVHFILVAQMDLVHYDHCSSVLQSYHPRSCTEQHWSIQRLIRDHQPNRLTISYLSERSTQDYMGDSFLINFIPLSANKYACLKVLHKVDKLKDFWGIWFRYQDWHHPFILKCYGLFKESCGFFRECADGPLFFNVYKNNQDFLFRDVLDVLYSIGSALDYLHRNLGQVHGNVNLKSIVRVGKNFKLSEASISESNSEVLEIAKYFDENLEEGRRRNPCITDVYGLLLSIMLIYFMNEDLKDHKVSQSSFRETKCLLKELILKAFQSQDMAISLLENLYKISVNFTDSTSDEVIVQKDNIFIPKCIEIYNRDAKIFQLNEIKPEELQIEKTPIGRGNFSTVFKAKYSRSKDNAIPVAAKWLNDKNDKTLNKIKTELFPSTFPHKNVLKSYGYCILKDQTYLISELAFQDLLRYLQSNQLPNDRTCINFCLQVCQGMKFLSDDRKFIHRDLAARNILVFKDKDENVTLKISDFGLTIKLMNKNYYNSNSQGNFFWLPDDEFKTGKFTVKTDIYSYGVVMWEIFSGGKDVVKMRKSHRTLPKEFDDIKILDGAYNLMKGCWSVGDLQPNDFNSLIHLLKALLE
Sbjct:    1 MIEIFPFVIVIYYMLMNNQNKDDVLSFLRNIFRMKDSMKFVILINRMMKNIQNVVTDELMCKSIDELIIKLSKNMITNIYFQTYYSRYLCITVTLNHLQVNNDMFNWNDISNATVTEKEKDFYLKIEMNDLFSDLAIDLPMKNEEEANSVHFILVAQMDLVHYDHCSSVLQSYHPRSCTEQHWSIQRLIRDHQPNRLTISYLSERSTQDYMGDSFLINFIPLSANKYACLKVLHKVDKLKDFWGIWFRYQDWHHPFILKCYGLFKESCGFFRECADGPLFFNVYKNNQDFLFRDVLDVLYSIGSALDYLHRNLGQVHGNVNLKSIVRVGKNFKLSEASISESNSEVLEIAKYFDENLEEGRRRNPCITDVYGLLLSIMLIYFMNEDLKDHKVSQSSFRETKCLLKELILKAFQSQDMAISLLENLYKISVNFTDSTSDEVIVQKDNIFIPKCIEIYNRDAKIFQLNEIKPEELQIEKTPIGRGNFSTVFKAKYSRSKDNAIPVAAKWLNDKNDKTLNKIKTELFPSTFPHKNVLKSYGYCILKDQTYLISELAFQDLLRYLQSNQLPNDRTCINFCLQVCQGMKFLSDDRKFIHRDLAARNILVFKDKDENVTLKISDFGLTIKLMNKNYYNSNSQGNFFWLPDDEFKTGKFTVKTDIYSYGVVMWEIFSGGKDVVKMRKSHRTLPKEFDDIKILDGAYNLMKGCWSVGDLQPNDFNSLIHLLKALLE 728

[Close]

BLAST of Hepatocyte growth factor receptor vs. Planmine SMEST
Match: SMESG000037119.1 (SMESG000037119.1)

HSP 1 Score: 1447.18 bits (3745), Expect = 0.000e+0
Identity = 715/715 (100.00%), Postives = 715/715 (100.00%), Query Frame = 3

Query:  405 MLMNNQNKDDVLSFLRNIFRMKDSMKFVILINRMMKNIQNVVTDELMCKSIDELIIKLSKNMITNIYFQTYYSRYLCITVTLNHLQVNNDMFNWNDISNATVTEKEKDFYLKIEMNDLFSDLAIDLPMKNEEEANSVHFILVAQMDLVHYDHCSSVLQSYHPRSCTEQHWSIQRLIRDHQPNRLTISYLSERSTQDYMGDSFLINFIPLSANKYACXXXXXXXXXXXXFWGIWFRYQDWHHPFILKCYGLFKESCGFFRECADGPLFFNVYKNNQDFLFRDVLDVLYSIGSALDYLHRNLGQVHGNVNLKSIVRVGKNFKLSEASISESNSEVLEIAKYFDENLEEGRRRNPCITDVYGLLLSIMLIYFMNEDLKDHKVSQSSFRETKCLLKELILKAFQSQDMAISLLENLYKISVNFTDSTSDEVIVQKDNIFIPKCIEIYNRDAKIFQLNEIKPEELQIEKTPIGRGNFSTVFKAKYSRSKDNAIPVAAKWLNDKNDKTLNKIKTELFPSTFPHKNVLKSYGYCILKDQTYLISELAFQDLLRYLQSNQLPNDRTCINFCLQVCQGMKFLSDDRKFIHRDLAARNILVFKDKDENVTLKISDFGLTIKLMNKNYYNSNSQGNFFWLPDDEFKTGKFTVKTDIYSYGVVMWEIFSGGKDVVKMRKSHRTLPKEFDDIKILDGAYNLMKGCWSVGDLQPNDFNSLIHLLKALLE 2549
            MLMNNQNKDDVLSFLRNIFRMKDSMKFVILINRMMKNIQNVVTDELMCKSIDELIIKLSKNMITNIYFQTYYSRYLCITVTLNHLQVNNDMFNWNDISNATVTEKEKDFYLKIEMNDLFSDLAIDLPMKNEEEANSVHFILVAQMDLVHYDHCSSVLQSYHPRSCTEQHWSIQRLIRDHQPNRLTISYLSERSTQDYMGDSFLINFIPLSANKYACLKVLHKVDKLKDFWGIWFRYQDWHHPFILKCYGLFKESCGFFRECADGPLFFNVYKNNQDFLFRDVLDVLYSIGSALDYLHRNLGQVHGNVNLKSIVRVGKNFKLSEASISESNSEVLEIAKYFDENLEEGRRRNPCITDVYGLLLSIMLIYFMNEDLKDHKVSQSSFRETKCLLKELILKAFQSQDMAISLLENLYKISVNFTDSTSDEVIVQKDNIFIPKCIEIYNRDAKIFQLNEIKPEELQIEKTPIGRGNFSTVFKAKYSRSKDNAIPVAAKWLNDKNDKTLNKIKTELFPSTFPHKNVLKSYGYCILKDQTYLISELAFQDLLRYLQSNQLPNDRTCINFCLQVCQGMKFLSDDRKFIHRDLAARNILVFKDKDENVTLKISDFGLTIKLMNKNYYNSNSQGNFFWLPDDEFKTGKFTVKTDIYSYGVVMWEIFSGGKDVVKMRKSHRTLPKEFDDIKILDGAYNLMKGCWSVGDLQPNDFNSLIHLLKALLE
Sbjct:    1 MLMNNQNKDDVLSFLRNIFRMKDSMKFVILINRMMKNIQNVVTDELMCKSIDELIIKLSKNMITNIYFQTYYSRYLCITVTLNHLQVNNDMFNWNDISNATVTEKEKDFYLKIEMNDLFSDLAIDLPMKNEEEANSVHFILVAQMDLVHYDHCSSVLQSYHPRSCTEQHWSIQRLIRDHQPNRLTISYLSERSTQDYMGDSFLINFIPLSANKYACLKVLHKVDKLKDFWGIWFRYQDWHHPFILKCYGLFKESCGFFRECADGPLFFNVYKNNQDFLFRDVLDVLYSIGSALDYLHRNLGQVHGNVNLKSIVRVGKNFKLSEASISESNSEVLEIAKYFDENLEEGRRRNPCITDVYGLLLSIMLIYFMNEDLKDHKVSQSSFRETKCLLKELILKAFQSQDMAISLLENLYKISVNFTDSTSDEVIVQKDNIFIPKCIEIYNRDAKIFQLNEIKPEELQIEKTPIGRGNFSTVFKAKYSRSKDNAIPVAAKWLNDKNDKTLNKIKTELFPSTFPHKNVLKSYGYCILKDQTYLISELAFQDLLRYLQSNQLPNDRTCINFCLQVCQGMKFLSDDRKFIHRDLAARNILVFKDKDENVTLKISDFGLTIKLMNKNYYNSNSQGNFFWLPDDEFKTGKFTVKTDIYSYGVVMWEIFSGGKDVVKMRKSHRTLPKEFDDIKILDGAYNLMKGCWSVGDLQPNDFNSLIHLLKALLE 715

[Close]

BLAST of Hepatocyte growth factor receptor vs. Planmine SMEST
Match: SMESG000053399.1 (SMESG000053399.1)

HSP 1 Score: 106.301 bits (264), Expect = 7.354e-24
Identity = 82/261 (31.42%), Postives = 133/261 (50.96%), Query Frame = 3

Query: 1803 IGRGNFSTVFKAKYSRSKDNAIPVAAKWLNDKNDKTLNKIKTELFPSTFPHKNVLKSYGYCILK--DQTYLISE-LAFQDLLRYLQSN--QLPNDRTCINFCLQVCQGMKFLSDDRKFIHRDLAARNILVFKDKDENVTLKISDFGLTIKLMNKNYYNSNSQGNF--FWLPDDEFKTGKFTVKTDIYSYGVVMWEIFSGGK---------DVVKMRKSHRTLPKEFDDIKILDGAYNLMKGCWSVGDLQPNDFNSLIHLLK 2537
            IGRG+FS V  AK+   + N + VA K L+  +D     IK       F H+ + K  G C L   +  ++I+E +    +L YL++   Q    R  I   +++ +GM +L + + +IHRDL A NILV KDK    ++K++DFGL  +++   Y    +   F   W+  +  +  KF +K+D++S+G++M+E+ + GK         +V    ++   +PK     K  D  YN MK CW     +P+ F  L HL K
Sbjct:  209 IGRGHFSEVLLAKH---RLNNMFVAVKMLHKYHDDRKTFIKEAKVMHQFYHERIAKILGVCTLPITEPMFIITEYMENGSMLDYLKNREAQRIKSREKIIMLMEIAEGMAYL-ESKSYIHRDLRAANILVSKDK----SVKVADFGLA-RMVEDIYVAGEADYQFPVRWMAQEVLQDNKFNLKSDVWSFGILMYEVLTYGKLPYPDMANPEVAIQVRNGYIMPKP-TGYKCSDRFYNTMKSCWDKHRERPS-FQDLFHLFK 458

[Close]

BLAST of Hepatocyte growth factor receptor vs. Planmine SMEST
Match: SMESG000043611.1 (SMESG000043611.1)

HSP 1 Score: 107.071 bits (266), Expect = 2.154e-23
Identity = 88/275 (32.00%), Postives = 134/275 (48.73%), Query Frame = 3

Query: 1773 PEELQIEKTPIGRGNFSTVFKAKYSRSKDN-AIPVAAKWLNDKNDKTLNKIKTELFP-----STFPHKNVLKSYGYCILKDQTYLISELA-FQDLLRYLQSNQLPNDRTCINFCLQVCQGMKFLSDDRKFIHRDLAARNILVFKDKDENVTLKISDFGLTIKL-MNKNYYNSNSQGNFF--WLPDDEFKTGKFTVKTDIYSYGVVMWEIFSGGKDVVKMRKSHRTLPKEFDDIKIL-------DGAYNLMKGCWSVGDLQPNDFNSLIHLLKALL 2546
            P ++ I K  +G GNF  VF   Y  S     +PVA K L  K D+  N I+ ++       +   H+++++  G C    Q  L+ ELA    + +YL+ NQ  N  +      QV  GM +L +  KF+HRDLAARN+L+  DK      KISDFG++  L    +YY + + G +   W   +     +F  K+D++SYGV MWE+FS G    +  K  + L    D  K L       D  Y++M  CW    ++   F  L+ ++  +L
Sbjct:  565 PSQISI-KDKLGGGNFGHVFGGIYKPSDGKKEVPVAIKML--KQDQMSNIIEDDIMAEARVMAQLKHRHIVRLIGIC-RDAQVMLVLELAPLGPINKYLRKNQEMNYISITELMYQVALGMAYL-EASKFVHRDLAARNVLLVSDK----YAKISDFGMSKALKFGNDYYRAANAGKWPIKWYAPECIYYFRFDSKSDVWSYGVTMWEVFSYGDRPYRDMKGTQIL-AMIDRGKRLSKPHSCPDSIYDVMLQCWEFDGVRRPTFAELVLIISRIL 829

[Close]

BLAST of Hepatocyte growth factor receptor vs. Planmine SMEST
Match: SMESG000059351.1 (SMESG000059351.1)

HSP 1 Score: 102.064 bits (253), Expect = 7.825e-23
Identity = 73/228 (32.02%), Postives = 118/228 (51.75%), Query Frame = 3

Query: 1713 PKCIEIYNRDAKIFQLNEIKPEELQIEKTPIGRGNFSTVFKAKYSRSKDNAIPVAAKWLNDKNDKTLNKIKTELFPSTFPHKNVLKSYGYCILKDQTYLISELAFQ-DLLRYLQSNQLPNDRTCIN---FCLQVCQGMKFLSDDRKFIHRDLAARNILVFKDKDENVTLKISDFGLTIKLMNKNYYNSNSQGNFFWLPDDEFKTGKFTVKTDIYSYGVVMWEIFSGGK 2384
            P  I  + +   +F  + +  EE       +G+G+F+ VFKA Y     N   +AAK +   +D T   IK     +T  H+N+++ +G  I  D+ YL++E      L+ YL++    +  T IN   F + V  GM +L + +  +HRDLA RNIL+    D+N+  KI+DFGL       + Y    +    W   +  K  +F+  +D++S+GVV+WEI+S GK
Sbjct:  115 PPVIHYFQQAGWVFPRDGLDLEEC------LGKGDFAEVFKAHY-----NGKILAAKCVIQSSDLTFVGIKEASVMTTVRHQNLVQFHGLVIDSDKIYLLTEYMLNGSLVNYLRTRG-KSGITPINQLMFSINVACGMSYL-EQKDLVHRDLACRNILL----DKNMVAKIADFGLC---RETDSYELGGRVPIKWTAPEAVKNNQFSPMSDMWSFGVVLWEIYSFGK 322

The following BLAST results are available for this feature:

BLAST of Hepatocyte growth factor receptor vs. Ensembl Human
BLAST of Hepatocyte growth factor receptor vs. Ensembl Celegans
BLAST of Hepatocyte growth factor receptor vs. Ensembl Fly
BLAST of Hepatocyte growth factor receptor vs. Ensembl Zebrafish
BLAST of Hepatocyte growth factor receptor vs. Ensembl Xenopus
BLAST of Hepatocyte growth factor receptor vs. Ensembl Mouse
BLAST of Hepatocyte growth factor receptor vs. UniProt/SwissProt
BLAST of Hepatocyte growth factor receptor vs. TrEMBL
BLAST of Hepatocyte growth factor receptor vs. Ensembl Cavefish
BLAST of Hepatocyte growth factor receptor vs. Ensembl Sea Lamprey
BLAST of Hepatocyte growth factor receptor vs. Ensembl Yeast
BLAST of Hepatocyte growth factor receptor vs. Ensembl Nematostella
BLAST of Hepatocyte growth factor receptor vs. Ensembl Medaka
BLAST of Hepatocyte growth factor receptor vs. Planmine SMEST

BLAST of Hepatocyte growth factor receptor vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5


Match Name	E-value	Identity	Description
MET	1.653e-25	30.97	MET proto-oncogene, receptor tyrosine kinase [Sour...	[more]
MET	1.798e-25	30.97	MET proto-oncogene, receptor tyrosine kinase [Sour...	[more]
MST1R	7.621e-25	30.08	macrophage stimulating 1 receptor [Source:HGNC Sym...	[more]
MST1R	7.672e-25	30.08	macrophage stimulating 1 receptor [Source:HGNC Sym...	[more]
MST1R	8.512e-25	30.08	macrophage stimulating 1 receptor [Source:HGNC Sym...	[more]

BLAST of Hepatocyte growth factor receptor vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 5


Match Name	E-value	Identity	Description
egl-15	1.787e-25	29.39	Myoblast growth factor receptor egl-15 [Source:Un...	[more]
egl-15	1.811e-25	29.39	Myoblast growth factor receptor egl-15 [Source:Un...	[more]
egl-15	1.946e-25	29.39	Myoblast growth factor receptor egl-15 [Source:Un...	[more]
egl-15	1.946e-25	29.39	Myoblast growth factor receptor egl-15 [Source:Un...	[more]
egl-15	1.946e-25	29.39	Myoblast growth factor receptor egl-15 [Source:Un...	[more]

BLAST of Hepatocyte growth factor receptor vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5


Match Name	E-value	Identity	Description
Btk29A	1.135e-26	31.27	gene:FBgn0003502 transcript:FBtr0330693	[more]
Btk29A	2.379e-26	31.27	gene:FBgn0003502 transcript:FBtr0330692	[more]
Btk29A	3.617e-26	31.27	gene:FBgn0003502 transcript:FBtr0112835	[more]
Btk29A	3.617e-26	31.27	gene:FBgn0003502 transcript:FBtr0079618	[more]
Btk29A	3.617e-26	31.27	gene:FBgn0003502 transcript:FBtr0079615	[more]

BLAST of Hepatocyte growth factor receptor vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5


Match Name	E-value	Identity	Description
mst1ra	1.204e-26	28.99	macrophage stimulating 1 receptor a [Source:ZFIN;A...	[more]
met	5.375e-26	27.86	MET proto-oncogene, receptor tyrosine kinase [Sour...	[more]
met	5.375e-26	27.86	MET proto-oncogene, receptor tyrosine kinase [Sour...	[more]
btk	6.350e-26	31.02	Bruton agammaglobulinemia tyrosine kinase [Source:...	[more]
BX544890.1	2.722e-25	30.66	Bruton agammaglobulinemia tyrosine kinase [Source:...	[more]

BLAST of Hepatocyte growth factor receptor vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5


Match Name	E-value	Identity	Description
fez1	5.882e-24	29.17	fasciculation and elongation protein zeta 1 [Sourc...	[more]
fez1	5.914e-24	29.17	fasciculation and elongation protein zeta 1 [Sourc...	[more]
fez1	6.260e-24	29.17	fasciculation and elongation protein zeta 1 [Sourc...	[more]
fez1	6.537e-24	29.17	fasciculation and elongation protein zeta 1 [Sourc...	[more]
drc1	1.390e-23	29.84	dynein regulatory complex subunit 1 [Source:Xenbas...	[more]

BLAST of Hepatocyte growth factor receptor vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5


Match Name	E-value	Identity	Description
Met	1.690e-25	29.59	met proto-oncogene [Source:MGI Symbol;Acc:MGI:9696...	[more]
Met	1.690e-25	29.59	met proto-oncogene [Source:MGI Symbol;Acc:MGI:9696...	[more]
Met	1.690e-25	29.59	met proto-oncogene [Source:MGI Symbol;Acc:MGI:9696...	[more]
Bmx	5.966e-25	29.71	BMX non-receptor tyrosine kinase [Source:MGI Symbo...	[more]
Bmx	6.385e-25	29.71	BMX non-receptor tyrosine kinase [Source:MGI Symbo...	[more]

BLAST of Hepatocyte growth factor receptor vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5


Match Name	E-value	Identity	Description
sp\|Q2IBC0\|MET_RHIFE	2.925e-27	28.37	Hepatocyte growth factor receptor OS=Rhinolophus f...	[more]
sp\|P23049\|SEA_AVIET	1.218e-26	28.67	Tyrosine-protein kinase transforming protein SEA O...	[more]
sp\|Q00PJ8\|MET_ATEAB	1.547e-26	32.09	Hepatocyte growth factor receptor OS=Atelerix albi...	[more]
sp\|Q07E37\|MET_NEONE	2.544e-26	32.09	Hepatocyte growth factor receptor OS=Neofelis nebu...	[more]
sp\|A0M8S8\|MET_FELCA	2.544e-26	32.09	Hepatocyte growth factor receptor OS=Felis catus O...	[more]

BLAST of Hepatocyte growth factor receptor vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5


Match Name	E-value	Identity	Description
A0A336MEA8	1.964e-26	32.29	Tyrosine-protein kinase receptor OS=Culicoides son...	[more]
A0A336LGT4	2.503e-26	32.29	Tyrosine-protein kinase receptor OS=Culicoides son...	[more]
A0A0J7K479	6.885e-26	31.94	Tyrosine-protein kinase receptor OS=Lasius niger O...	[more]
A0A1S3JTZ5	1.167e-25	34.05	Tyrosine-protein kinase OS=Lingula unguis OX=7574 ...	[more]
A0A1S3JUM6	1.205e-25	34.05	Tyrosine-protein kinase OS=Lingula unguis OX=7574 ...	[more]

BLAST of Hepatocyte growth factor receptor vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5


Match Name	E-value	Identity	Description
met	3.193e-26	29.70	MET proto-oncogene, receptor tyrosine kinase [Sour...	[more]
met	1.988e-25	29.96	MET proto-oncogene, receptor tyrosine kinase [Sour...	[more]
btk	2.249e-25	30.18	Bruton agammaglobulinemia tyrosine kinase [Source:...	[more]
btk	2.518e-25	30.60	Bruton agammaglobulinemia tyrosine kinase [Source:...	[more]
mst1rb	2.105e-24	29.32	macrophage stimulating 1 receptor [Source:NCBI gen...	[more]

BLAST of Hepatocyte growth factor receptor vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 5


Match Name	E-value	Identity	Description
ENSPMAT00000009736.1	4.767e-25	31.11	pep scaffold:Pmarinus_7.0:GL479388:5844:12989:-1 g...	[more]
frk	2.839e-23	27.76	fyn-related Src family tyrosine kinase [Source:ZFI...	[more]
ENSPMAT00000004129.1	6.056e-23	31.51	pep scaffold:Pmarinus_7.0:GL490249:304:4500:1 gene...	[more]
txk	6.168e-23	26.91	TXK tyrosine kinase [Source:ZFIN;Acc:ZDB-GENE-1305...	[more]
ENSPMAT00000001705.1	6.916e-23	31.03	pep scaffold:Pmarinus_7.0:GL487204:7598:9057:-1 ge...	[more]

BLAST of Hepatocyte growth factor receptor vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 5


Match Name	E-value	Identity	Description
STE11	6.932e-11	31.51	Signal transducing MEK kinase; involved in pheromo...	[more]
CLA4	1.253e-10	31.91	Cdc42p-activated signal transducing kinase; member...	[more]
PHO85	2.810e-10	25.60	Cyclin-dependent kinase; has ten cyclin partners; ...	[more]
SPS1	3.466e-10	27.01	Putative protein serine/threonine kinase; localize...	[more]
CDC15	6.409e-10	27.41	Protein kinase of the Mitotic Exit Network; locali...	[more]

BLAST of Hepatocyte growth factor receptor vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 5


Match Name	E-value	Identity	Description
EDO49804	5.831e-26	33.33	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO31298	7.589e-26	31.42	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO49035	3.887e-24	28.32	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO39121	1.968e-23	29.63	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO35408	7.085e-23	27.08	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]

BLAST of Hepatocyte growth factor receptor vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5


Match Name	E-value	Identity	Description
mst1ra	1.181e-26	31.10	macrophage-stimulating protein receptor-like [Sour...	[more]
mst1ra	1.304e-26	31.10	macrophage-stimulating protein receptor-like [Sour...	[more]
met	9.453e-26	27.48	MET proto-oncogene, receptor tyrosine kinase [Sour...	[more]
mst1rb	1.951e-25	30.34	macrophage stimulating 1 receptor [Source:NCBI gen...	[more]
mst1rb	2.187e-25	30.34	macrophage stimulating 1 receptor [Source:NCBI gen...	[more]

BLAST of Hepatocyte growth factor receptor vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5


Match Name	E-value	Identity	Description
SMESG000037119.1	0.000e+0	100.00	SMESG000037119.1	[more]
SMESG000037119.1	0.000e+0	100.00	SMESG000037119.1	[more]
SMESG000053399.1	7.354e-24	31.42	SMESG000053399.1	[more]
SMESG000043611.1	2.154e-23	32.00	SMESG000043611.1	[more]
SMESG000059351.1	7.825e-23	32.02	SMESG000059351.1	[more]

Analyses

This transcript is derived from or has results from the following analyses


Analysis Name	Date Performed
Embryonic Stages	2016-07-25
Schmidtea mediterranea smed_20140614 BLASTX Human e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL	2020-05-01
Schmidtea mediterranea Sexual smed_20140614 transcriptome	2016-07-25
Schmidtea mediteranean smed_20140614 Interproscan	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST	2020-05-08

Sequences

The following sequences are available for this feature:

transcript sequence
protein sequence

transcript sequence

>SMED30013495 ID=SMED30013495|Name=Hepatocyte growth factor receptor|organism=Schmidtea mediterranea sexual|type=transcript|length=2633bp
TGAAAAGTTAAAACTTTGTTTCAATTATTATTAGCAATCTCATAATTTTG
TTTCAAAATTTTTGCCAAATGCTATTTAATAATGATGTTAATTATTTGAA
ATTTAATGAAAAAGATTTAAATTTTTTCCTTCAAAATGTGCCAGATTTTT
TTCATCATATATTTGCTTTCTATGACAATGTAAAGAATAAATGGATCAAA
TTGAAAAACACACATTTCAAATCAACAAAAAGCATAAAAATTCTCCCAAA
TGTTCTATTTAACTGTGAATCGACACTAAATTTCGTATTACATTTTTTAT
CTTCAGATGTAAAAATTTATAGATTTTTTGTTATTATTTTAATCCAAGAA
TACGAACCTTCATATATGATTGAAATATTTCCGTTTGTTATTGTTATTTA
TTATATGTTAATGAATAATCAAAATAAAGATGATGTATTAAGTTTCCTAA
GGAATATCTTTCGAATGAAAGATAGTATGAAATTTGTCATACTAATAAAT
CGAATGATGAAAAATATCCAAAATGTCGTAACCGATGAATTAATGTGTAA
ATCAATTGATGAGCTAATAATAAAATTGTCTAAAAATATGATAACGAATA
TCTATTTCCAAACTTATTATAGTCGATATTTATGTATCACGGTAACATTG
AATCATTTACAAGTGAATAACGATATGTTCAACTGGAACGATATATCAAA
CGCAACTGTAACTGAAAAGGAAAAAGATTTCTATCTAAAAATAGAAATGA
ACGATTTATTTTCTGATTTAGCGATTGATTTACCAATGAAAAATGAAGAG
GAAGCTAATTCGGTTCATTTTATATTGGTTGCTCAAATGGATCTCGTACA
TTATGATCATTGTTCATCGGTACTGCAATCTTATCATCCGCGCAGTTGCA
CCGAACAGCACTGGAGCATTCAACGGCTTATCCGTGATCACCAGCCCAAC
CGGTTGACAATATCATACTTATCTGAGAGGAGTACACAAGATTACATGGG
AGACAGTTTCCTCATCAATTTCATCCCTCTTTCAGCCAATAAATACGCCT
GCTTGAAGGTGCTGCACAAAGTGGATAAATTGAAGGATTTCTGGGGCATC
TGGTTTCGGTATCAAGATTGGCATCACCCATTCATTCTCAAATGCTACGG
ACTTTTTAAGGAGTCTTGCGGATTTTTCCGTGAGTGTGCTGATGGGCCTC
TGTTTTTTAACGTATACAAGAACAATCAGGATTTCCTATTTCGGGACGTT
TTGGACGTGTTATATTCCATTGGTAGTGCATTGGATTATTTGCATCGCAA
CCTTGGACAAGTCCATGGCAACGTTAATCTCAAGAGCATTGTCAGAGTTG
GTAAAAATTTCAAGCTATCCGAAGCGTCTATTAGCGAATCAAATTCAGAA
GTTTTAGAAATAGCCAAATATTTCGATGAAAATCTGGAAGAAGGAAGAAG
AAGGAATCCATGTATTACAGATGTATATGGTCTGTTATTGAGCATCATGC
TAATTTATTTTATGAACGAGGATCTCAAGGATCACAAGGTATCTCAATCT
TCATTTCGGGAGACTAAATGCTTGCTGAAGGAATTGATTCTGAAAGCCTT
CCAGTCCCAGGACATGGCCATAAGTTTATTAGAAAATCTCTACAAGATTT
CAGTGAATTTCACTGACTCTACATCAGATGAGGTAATTGTACAGAAGGAT
AATATATTTATACCGAAATGTATTGAAATATACAACAGAGATGCGAAAAT
ATTTCAACTCAATGAGATCAAGCCTGAGGAATTGCAAATTGAAAAAACTC
CTATCGGCAGAGGAAATTTCTCAACAGTTTTCAAGGCCAAATATTCCCGA
TCAAAAGATAATGCCATTCCTGTTGCTGCTAAATGGTTGAATGATAAAAA
TGATAAAACCTTGAATAAAATTAAAACGGAGTTGTTTCCCTCAACCTTTC
CGCACAAGAATGTGTTGAAATCGTACGGATATTGCATTCTAAAAGACCAG
ACCTACCTGATTAGCGAATTGGCGTTTCAGGATCTGCTTAGGTATCTCCA
ATCAAATCAGCTCCCGAATGATAGAACTTGCATCAATTTCTGCCTTCAGG
TTTGTCAGGGAATGAAGTTTCTGTCCGATGACCGGAAATTCATTCATCGT
GACCTCGCGGCCAGAAATATTCTCGTATTCAAAGATAAAGATGAAAATGT
CACTTTAAAAATTAGTGACTTTGGATTGACAATCAAATTAATGAATAAAA
ATTATTACAACAGCAATAGTCAAGGAAACTTCTTTTGGTTGCCTGATGAT
GAATTCAAAACAGGGAAATTTACCGTGAAAACTGACATTTATAGTTATGG
AGTCGTTATGTGGGAAATTTTCTCTGGCGGGAAAGATGTTGTAAAAATGA
GAAAATCTCACCGCACTTTGCCAAAGGAATTTGACGATATCAAAATCCTT
GATGGTGCCTACAACTTAATGAAGGGTTGCTGGAGCGTCGGTGATCTTCA
ACCAAATGATTTCAACTCGTTAATTCACTTATTAAAAGCCTTGCTTGAAT
GAACCTCTGTTAATGTTTTCGTTTTACAAATATATAGATAAATCGCCAAT
GAAAATTCCAATGAAACCCCACCTCTCCTGAGT

protein sequence of SMED30013495-orf-1

>SMED30013495-orf-1 ID=SMED30013495-orf-1|Name=SMED30013495-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=828bp
MLFNNDVNYLKFNEKDLNFFLQNVPDFFHHIFAFYDNVKNKWIKLKNTHF
KSTKSIKILPNVLFNCESTLNFVLHFLSSDVKIYRFFVIILIQEYEPSYM
IEIFPFVIVIYYMLMNNQNKDDVLSFLRNIFRMKDSMKFVILINRMMKNI
QNVVTDELMCKSIDELIIKLSKNMITNIYFQTYYSRYLCITVTLNHLQVN
NDMFNWNDISNATVTEKEKDFYLKIEMNDLFSDLAIDLPMKNEEEANSVH
FILVAQMDLVHYDHCSSVLQSYHPRSCTEQHWSIQRLIRDHQPNRLTISY
LSERSTQDYMGDSFLINFIPLSANKYACLKVLHKVDKLKDFWGIWFRYQD
WHHPFILKCYGLFKESCGFFRECADGPLFFNVYKNNQDFLFRDVLDVLYS
IGSALDYLHRNLGQVHGNVNLKSIVRVGKNFKLSEASISESNSEVLEIAK
YFDENLEEGRRRNPCITDVYGLLLSIMLIYFMNEDLKDHKVSQSSFRETK
CLLKELILKAFQSQDMAISLLENLYKISVNFTDSTSDEVIVQKDNIFIPK
CIEIYNRDAKIFQLNEIKPEELQIEKTPIGRGNFSTVFKAKYSRSKDNAI
PVAAKWLNDKNDKTLNKIKTELFPSTFPHKNVLKSYGYCILKDQTYLISE
LAFQDLLRYLQSNQLPNDRTCINFCLQVCQGMKFLSDDRKFIHRDLAARN
ILVFKDKDENVTLKISDFGLTIKLMNKNYYNSNSQGNFFWLPDDEFKTGK
FTVKTDIYSYGVVMWEIFSGGKDVVKMRKSHRTLPKEFDDIKILDGAYNL
MKGCWSVGDLQPNDFNSLIHLLKALLE*

Annotated Terms

The following terms have been associated with this transcript:

Vocabulary: **molecular function**
Term	Definition
GO:0000166	nucleotide binding
GO:0004714	transmembrane receptor protein tyrosine kinase activity
GO:0016301	kinase activity
GO:0016740	transferase activity
GO:0017154	semaphorin receptor activity
GO:0004713	protein tyrosine kinase activity
GO:0004672	protein kinase activity
GO:0005524	ATP binding

Vocabulary: **biological process**
Term	Definition
GO:0007169	transmembrane receptor protein tyrosine kinase signaling pathway
GO:0016310	phosphorylation
GO:0050918	positive chemotaxis
GO:0071526	semaphorin-plexin signaling pathway
GO:2001028	positive regulation of endothelial cell chemotaxis
GO:0006468	protein phosphorylation
GO:0018108	peptidyl-tyrosine phosphorylation

Vocabulary: **Planarian Anatomy**
Term	Definition
PLANA:0002109	X1 cell

Vocabulary: **INTERPRO**
Term	Definition
IPR020635	Tyr_kinase_cat_dom
IPR001245	Ser-Thr/Tyr_kinase_cat_dom
IPR008266	Tyr_kinase_AS
IPR017441	Protein_kinase_ATP_BS
IPR000719	Prot_kinase_dom
IPR011009	Kinase-like_dom_sf

Vocabulary: **cellular component**
Term	Definition
GO:0016020	membrane
GO:0016021	integral component of membrane

InterPro

Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01


IPR Term	IPR Description	Source	Source Term	Source Description	Alignment
IPR020635	Tyrosine-protein kinase, catalytic domain	SMART	SM00219	tyrkin_6	coord: 573..822 e-value: 2.0E-35 score: 133.7
None	No IPR available	GENE3D	G3DSA:1.10.510.10		coord: 565..827 e-value: 7.7E-45 score: 154.9
None	No IPR available	GENE3D	G3DSA:1.10.510.10		coord: 347..471 e-value: 3.6E-5 score: 25.1
None	No IPR available	PANTHER	PTHR24418	TYROSINE-PROTEIN KINASE	coord: 561..806
IPR001245	Serine-threonine/tyrosine-protein kinase, catalytic domain	PFAM	PF07714	Pkinase_Tyr	coord: 577..820 e-value: 8.8E-48 score: 162.8
IPR017441	Protein kinase, ATP binding site	PROSITE	PS00107	PROTEIN_KINASE_ATP	coord: 579..605
IPR008266	Tyrosine-protein kinase, active site	PROSITE	PS00109	PROTEIN_KINASE_TYR	coord: 691..703
IPR000719	Protein kinase domain	PROSITE	PS50011	PROTEIN_KINASE_DOM	coord: 573..827 score: 24.16
IPR011009	Protein kinase-like domain superfamily	SUPERFAMILY	SSF56112	Protein kinase-like (PK-like)	coord: 323..434
IPR011009	Protein kinase-like domain superfamily	SUPERFAMILY	SSF56112	Protein kinase-like (PK-like)	coord: 565..807