Dihydropyrimidinase
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Overview
Neoblast Clusters
Zeng et. al., 2018▻ Overview▻ Neoblast Population▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Overview
Single cell RNA-seq of pluripotent neoblasts and its early progeniesWe isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)Explore this single cell expression dataset with our NB Cluster Shiny App
Neoblast Population
Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Embryonic Expression
Davies et. al., 2017
Hover the mouse over a column in the graph to view average RPKM values per sample. Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult. back to top Anatomical Expression
PAGE et. al., 2020SMED30013480 has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGEPAGE Curations: 22Note: Hover over icons to view figure legend
Homology
BLAST of Dihydropyrimidinase vs. Ensembl Human
Match: DPYSL3 (dihydropyrimidinase like 3 [Source:HGNC Symbol;Acc:HGNC:3015]) HSP 1 Score: 302.753 bits (774), Expect = 7.810e-94 Identity = 175/505 (34.65%), Postives = 280/505 (55.45%), Query Frame = 2
Query: 149 TQKKLLIKCGTVINHDCTYDADVLIENGKIVNIAKN-IEDSLAECIDATGCFVLPGGVDAETNFAAKRGGIVSPENYFSGTKAAIYGGTTTVVNCLEIMKDESLKEKYEMEKDIISKEIVCNLAIQLCLPEVNEAIKSEFNELLQSKSVVP-LVRLSTVDKGCHCVKIDDEELYDALCWCRDNSVLPTVHAENDKMVAILEKELLADGVTGPEGHYLSRPEKVEDEAVFRVLTIAEMVKCPIHFGKVYAKSSLDKIMDWQRKSSNTIICGTSLVALVHNAEKYRDPNWKVAASFVTMPALKMNKTTEFQCTELLETVASRKINHVASSHLVFDMKHKASGRNDFRCIIPGTNGVQYRMKILWDKAVKSGRMEPTSFVNCVSTTPAKLANIYPHKGTISIGSDADIIVWKGDSV----SHSNFEAGDINVFEDVICHSGPKYVIVNGIVVLDHEGNFTASKGSGQIVSPSLETMNSYFQKQLINYKLSHEVEKKIAREPYDGPVID 1645
T +LLIK G ++N D ++ AD+ +E+G I I N I + I+A G V+PGG+D T+F G+ + +++F GTKAA+ GGTT +++ + + SL E YE ++ + C+ A+ + + N+++K E L++ K V +V ++ D ++ + ELY+ + + VHAEN ++A + +L G+TGPEGH LSRPE++E EAVFR +TIA CP++ KV +KS+ D ++ RK N + +L + Y NW AA+FVT P L + TT LL AS + S+H F KA G+++F I GTNGV+ RM ++WDKAV +G+M+ FV ST AK+ N+YP KG IS+GSD+D+++W D+V + ++ A + N+FE + P VI G ++L+ +GN ++G+G+ + S + Y K++ + ++ + R YDGPV D
Sbjct: 13 TSDRLLIKGGRIVNDDQSFYADIYMEDGLIKQIGDNLIVPGGVKTIEANGKMVIPGGIDVHTHFQMPYKGMTTVDDFFQGTKAALAGGTTMIIDHVVPEPESSLTEAYEKWREWADGKSCCDYALHVDITHWNDSVKQEVQNLIKDKGVNSFMVYMAYKD----LYQVSNTELYEIFTCLGELGAIAQVHAENGDIIAQEQTRMLEMGITGPEGHVLSRPEELEAEAVFRAITIASQTNCPLYVTKVMSKSAAD-LISQARKKGNVVFGEPITASLGIDGTHYWSKNWAKAAAFVTSPPLSPDPTTPDYINSLL---ASGDLQLSGSAHCTFSTAQKAIGKDNFTAIPEGTNGVEERMSVIWDKAVATGKMDENQFVAVTSTNAAKIFNLYPRKGRISVGSDSDLVIWDPDAVKIVSAKNHQSAAEYNIFEGMELRGAPLVVICQGKIMLE-DGNLHVTQGAGRFIPCS--PFSDYVYKRIKARRKMADLH-AVPRGMYDGPVFD 505
BLAST of Dihydropyrimidinase vs. Ensembl Human
Match: DPYSL3 (dihydropyrimidinase like 3 [Source:HGNC Symbol;Acc:HGNC:3015]) HSP 1 Score: 302.753 bits (774), Expect = 1.400e-92 Identity = 176/516 (34.11%), Postives = 285/516 (55.23%), Query Frame = 2
Query: 116 KLLIKVLFMSETQKKLLIKCGTVINHDCTYDADVLIENGKIVNIAKN-IEDSLAECIDATGCFVLPGGVDAETNFAAKRGGIVSPENYFSGTKAAIYGGTTTVVNCLEIMKDESLKEKYEMEKDIISKEIVCNLAIQLCLPEVNEAIKSEFNELLQSKSVVP-LVRLSTVDKGCHCVKIDDEELYDALCWCRDNSVLPTVHAENDKMVAILEKELLADGVTGPEGHYLSRPEKVEDEAVFRVLTIAEMVKCPIHFGKVYAKSSLDKIMDWQRKSSNTIICGTSLVALVHNAEKYRDPNWKVAASFVTMPALKMNKTTEFQCTELLETVASRKINHVASSHLVFDMKHKASGRNDFRCIIPGTNGVQYRMKILWDKAVKSGRMEPTSFVNCVSTTPAKLANIYPHKGTISIGSDADIIVWKGDSV----SHSNFEAGDINVFEDVICHSGPKYVIVNGIVVLDHEGNFTASKGSGQIVSPSLETMNSYFQKQLINYKLSHEVEKKIAREPYDGPVID 1645
K +++ L + +LLIK G ++N D ++ AD+ +E+G I I N I + I+A G V+PGG+D T+F G+ + +++F GTKAA+ GGTT +++ + + SL E YE ++ + C+ A+ + + N+++K E L++ K V +V ++ D ++ + ELY+ + + VHAEN ++A + +L G+TGPEGH LSRPE++E EAVFR +TIA CP++ KV +KS+ D ++ RK N + +L + Y NW AA+FVT P L + TT LL AS + S+H F KA G+++F I GTNGV+ RM ++WDKAV +G+M+ FV ST AK+ N+YP KG IS+GSD+D+++W D+V + ++ A + N+FE + P VI G ++L+ +GN ++G+G+ + S + Y K++ + ++ + R YDGPV D
Sbjct: 116 KEVLQNLGPKDKSDRLLIKGGRIVNDDQSFYADIYMEDGLIKQIGDNLIVPGGVKTIEANGKMVIPGGIDVHTHFQMPYKGMTTVDDFFQGTKAALAGGTTMIIDHVVPEPESSLTEAYEKWREWADGKSCCDYALHVDITHWNDSVKQEVQNLIKDKGVNSFMVYMAYKD----LYQVSNTELYEIFTCLGELGAIAQVHAENGDIIAQEQTRMLEMGITGPEGHVLSRPEELEAEAVFRAITIASQTNCPLYVTKVMSKSAAD-LISQARKKGNVVFGEPITASLGIDGTHYWSKNWAKAAAFVTSPPLSPDPTTPDYINSLL---ASGDLQLSGSAHCTFSTAQKAIGKDNFTAIPEGTNGVEERMSVIWDKAVATGKMDENQFVAVTSTNAAKIFNLYPRKGRISVGSDSDLVIWDPDAVKIVSAKNHQSAAEYNIFEGMELRGAPLVVICQGKIMLE-DGNLHVTQGAGRFIPCS--PFSDYVYKRIKARRKMADLH-AVPRGMYDGPVFD 619
BLAST of Dihydropyrimidinase vs. Ensembl Human
Match: DPYSL5 (dihydropyrimidinase like 5 [Source:HGNC Symbol;Acc:HGNC:20637]) HSP 1 Score: 294.664 bits (753), Expect = 8.070e-91 Identity = 184/575 (32.00%), Postives = 294/575 (51.13%), Query Frame = 2
Query: 134 LFMSETQKKLLIKCGTVINHDCTYDADVLIENGKIVNIAKNIE-DSLAECIDATGCFVLPGGVDAETNFAAKRGGIVSPENYFSGTKAAIYGGTTTVVNCLEIMKDESLKEKYEMEKDIISKEIVCNLAIQLCLPEVNEAIKSEFNELLQSKSVVPLVRLSTVDKGCHCVKIDDEELYDALCWCRDNSVLPTVHAENDKMVAILEKELLADGVTGPEGHYLSRPEKVEDEAVFRVLTIAEMVKCPIHFGKVYAKSSLDKIMDWQRKSSNTIICGTSLVALVHNAEKYRDPNWKVAASFVTMPALKMNKTTEFQCTELLETVASRKINHVASSHLVFDMKHKASGRNDFRCIIPGTNGVQYRMKILWDKAVKSGRMEPTSFVNCVSTTPAKLANIYPHKGTISIGSDADIIVWKGDSV----SHSNFEAGDINVFEDVICHSGPKYVIVNGIVVLDHEGNFTASKGSGQIVSPSLETMNSYFQKQLINYKLSHEVEKKIAREPYDGPVIDPSADNKEEKHVLYSHMVNNDVYKRGGPAEDKKEALPPGQRVI------RTSVKTAQPPGGSAQASW 1825
+ + ++LIK G V+N DCT++ADV IENG I + + + A+ IDATG V+PGG+D T+F ++++ GTKAA+ GGTT ++ + K+ SL + YE + + ++ C+ A+ + + +K+E L++ K V T + D ELY L C+D + VHAEN ++VA KE L G+TGPEG +SRPE++E EA RV+TIA CPI+ V + S+ D ++ + ++ T+ Y +W AA++VT+P L+++ T T L+ +A+ +N VAS H F K KA G+ DF I G +GVQ RM ++W++ V G+M+ FV S+ AKL N+YP KG I G+DAD++VW ++ + + + GD N++E++ CH P I G VV ++ G F ++G+G+ L + K+L+ + + +V + + R PY G V K+E + V + GG + + + I R S + PPGG + W
Sbjct: 1 MLANSASVRILIKGGKVVNDDCTHEADVYIENGIIQQVGRELMIPGGAKVIDATGKLVIPGGIDTSTHFHQTFMNATCVDDFYHGTKAALVGGTTMIIGHVLPDKETSLVDAYEKCRGLADPKVCCDYALHVGITWWAPKVKAEMETLVREKGVNSFQMFMTYKD---LYMLRDSELYQVLHACKDIGAIARVHAENGELVAEGAKEALDLGITGPEGIEISRPEELEAEATHRVITIANRTHCPIYLVNVSSISAGD-VIAAAKMQGKVVLAETTTAHATLTGLHYYHQDWSHAAAYVTVPPLRLDTNTS---TYLMSLLANDTLNIVASDHRPFTTKQKAMGKEDFTKIPHGVSGVQDRMSVIWERGVVGGKMDENRFVAVTSSNAAKLLNLYPRKGRIIPGADADVVVWDPEATKTISASTQVQGGDFNLYENMRCHGVPLVTISRGRVVYEN-GVFMCAEGTGKFC--PLRSFPDTVYKKLVQREKTLKV-RGVDRTPYLGDVAVVVHPGKKEMGTPLADTPTRPVTRHGGMRDLHESSFSLSGSQIDDHVPKRASARILAPPGGRSSGIW 564
BLAST of Dihydropyrimidinase vs. Ensembl Human
Match: DPYSL5 (dihydropyrimidinase like 5 [Source:HGNC Symbol;Acc:HGNC:20637]) HSP 1 Score: 294.664 bits (753), Expect = 8.070e-91 Identity = 184/575 (32.00%), Postives = 294/575 (51.13%), Query Frame = 2
Query: 134 LFMSETQKKLLIKCGTVINHDCTYDADVLIENGKIVNIAKNIE-DSLAECIDATGCFVLPGGVDAETNFAAKRGGIVSPENYFSGTKAAIYGGTTTVVNCLEIMKDESLKEKYEMEKDIISKEIVCNLAIQLCLPEVNEAIKSEFNELLQSKSVVPLVRLSTVDKGCHCVKIDDEELYDALCWCRDNSVLPTVHAENDKMVAILEKELLADGVTGPEGHYLSRPEKVEDEAVFRVLTIAEMVKCPIHFGKVYAKSSLDKIMDWQRKSSNTIICGTSLVALVHNAEKYRDPNWKVAASFVTMPALKMNKTTEFQCTELLETVASRKINHVASSHLVFDMKHKASGRNDFRCIIPGTNGVQYRMKILWDKAVKSGRMEPTSFVNCVSTTPAKLANIYPHKGTISIGSDADIIVWKGDSV----SHSNFEAGDINVFEDVICHSGPKYVIVNGIVVLDHEGNFTASKGSGQIVSPSLETMNSYFQKQLINYKLSHEVEKKIAREPYDGPVIDPSADNKEEKHVLYSHMVNNDVYKRGGPAEDKKEALPPGQRVI------RTSVKTAQPPGGSAQASW 1825
+ + ++LIK G V+N DCT++ADV IENG I + + + A+ IDATG V+PGG+D T+F ++++ GTKAA+ GGTT ++ + K+ SL + YE + + ++ C+ A+ + + +K+E L++ K V T + D ELY L C+D + VHAEN ++VA KE L G+TGPEG +SRPE++E EA RV+TIA CPI+ V + S+ D ++ + ++ T+ Y +W AA++VT+P L+++ T T L+ +A+ +N VAS H F K KA G+ DF I G +GVQ RM ++W++ V G+M+ FV S+ AKL N+YP KG I G+DAD++VW ++ + + + GD N++E++ CH P I G VV ++ G F ++G+G+ L + K+L+ + + +V + + R PY G V K+E + V + GG + + + I R S + PPGG + W
Sbjct: 1 MLANSASVRILIKGGKVVNDDCTHEADVYIENGIIQQVGRELMIPGGAKVIDATGKLVIPGGIDTSTHFHQTFMNATCVDDFYHGTKAALVGGTTMIIGHVLPDKETSLVDAYEKCRGLADPKVCCDYALHVGITWWAPKVKAEMETLVREKGVNSFQMFMTYKD---LYMLRDSELYQVLHACKDIGAIARVHAENGELVAEGAKEALDLGITGPEGIEISRPEELEAEATHRVITIANRTHCPIYLVNVSSISAGD-VIAAAKMQGKVVLAETTTAHATLTGLHYYHQDWSHAAAYVTVPPLRLDTNTS---TYLMSLLANDTLNIVASDHRPFTTKQKAMGKEDFTKIPHGVSGVQDRMSVIWERGVVGGKMDENRFVAVTSSNAAKLLNLYPRKGRIIPGADADVVVWDPEATKTISASTQVQGGDFNLYENMRCHGVPLVTISRGRVVYEN-GVFMCAEGTGKFC--PLRSFPDTVYKKLVQREKTLKV-RGVDRTPYLGDVAVVVHPGKKEMGTPLADTPTRPVTRHGGMRDLHESSFSLSGSQIDDHVPKRASARILAPPGGRSSGIW 564
BLAST of Dihydropyrimidinase vs. Ensembl Human
Match: DPYSL5 (dihydropyrimidinase like 5 [Source:HGNC Symbol;Acc:HGNC:20637]) HSP 1 Score: 294.664 bits (753), Expect = 8.070e-91 Identity = 184/575 (32.00%), Postives = 294/575 (51.13%), Query Frame = 2
Query: 134 LFMSETQKKLLIKCGTVINHDCTYDADVLIENGKIVNIAKNIE-DSLAECIDATGCFVLPGGVDAETNFAAKRGGIVSPENYFSGTKAAIYGGTTTVVNCLEIMKDESLKEKYEMEKDIISKEIVCNLAIQLCLPEVNEAIKSEFNELLQSKSVVPLVRLSTVDKGCHCVKIDDEELYDALCWCRDNSVLPTVHAENDKMVAILEKELLADGVTGPEGHYLSRPEKVEDEAVFRVLTIAEMVKCPIHFGKVYAKSSLDKIMDWQRKSSNTIICGTSLVALVHNAEKYRDPNWKVAASFVTMPALKMNKTTEFQCTELLETVASRKINHVASSHLVFDMKHKASGRNDFRCIIPGTNGVQYRMKILWDKAVKSGRMEPTSFVNCVSTTPAKLANIYPHKGTISIGSDADIIVWKGDSV----SHSNFEAGDINVFEDVICHSGPKYVIVNGIVVLDHEGNFTASKGSGQIVSPSLETMNSYFQKQLINYKLSHEVEKKIAREPYDGPVIDPSADNKEEKHVLYSHMVNNDVYKRGGPAEDKKEALPPGQRVI------RTSVKTAQPPGGSAQASW 1825
+ + ++LIK G V+N DCT++ADV IENG I + + + A+ IDATG V+PGG+D T+F ++++ GTKAA+ GGTT ++ + K+ SL + YE + + ++ C+ A+ + + +K+E L++ K V T + D ELY L C+D + VHAEN ++VA KE L G+TGPEG +SRPE++E EA RV+TIA CPI+ V + S+ D ++ + ++ T+ Y +W AA++VT+P L+++ T T L+ +A+ +N VAS H F K KA G+ DF I G +GVQ RM ++W++ V G+M+ FV S+ AKL N+YP KG I G+DAD++VW ++ + + + GD N++E++ CH P I G VV ++ G F ++G+G+ L + K+L+ + + +V + + R PY G V K+E + V + GG + + + I R S + PPGG + W
Sbjct: 1 MLANSASVRILIKGGKVVNDDCTHEADVYIENGIIQQVGRELMIPGGAKVIDATGKLVIPGGIDTSTHFHQTFMNATCVDDFYHGTKAALVGGTTMIIGHVLPDKETSLVDAYEKCRGLADPKVCCDYALHVGITWWAPKVKAEMETLVREKGVNSFQMFMTYKD---LYMLRDSELYQVLHACKDIGAIARVHAENGELVAEGAKEALDLGITGPEGIEISRPEELEAEATHRVITIANRTHCPIYLVNVSSISAGD-VIAAAKMQGKVVLAETTTAHATLTGLHYYHQDWSHAAAYVTVPPLRLDTNTS---TYLMSLLANDTLNIVASDHRPFTTKQKAMGKEDFTKIPHGVSGVQDRMSVIWERGVVGGKMDENRFVAVTSSNAAKLLNLYPRKGRIIPGADADVVVWDPEATKTISASTQVQGGDFNLYENMRCHGVPLVTISRGRVVYEN-GVFMCAEGTGKFC--PLRSFPDTVYKKLVQREKTLKV-RGVDRTPYLGDVAVVVHPGKKEMGTPLADTPTRPVTRHGGMRDLHESSFSLSGSQIDDHVPKRASARILAPPGGRSSGIW 564
BLAST of Dihydropyrimidinase vs. Ensembl Celegans
Match: dhp-2 (Dihydropyrimidinase 2 [Source:UniProtKB/Swiss-Prot;Acc:Q18677]) HSP 1 Score: 268.47 bits (685), Expect = 7.802e-82 Identity = 172/557 (30.88%), Postives = 286/557 (51.35%), Query Frame = 2
Query: 161 LLIKCGTVINHDCTYDADVLIENGKIVNIAKNIEDSLA-ECIDATGCFVLPGGVDAETNFAAKRGGIVSPENYFSGTKAAIYGGTTTVVNCLEIMKDESLKEKYEMEKDIISKEIVCNLAIQLCLPEVNEAIKSEFNELLQSKSVVPLVRLSTVDKGCHCVKIDDEELYDALCWCRDNSVLPTVHAENDKMVAILEKELLADGVTGPEGHYLSRPEKVEDEAVFRVLTIAEMVKCPIHFGKVYAKSSLDKIMDWQRKSSNTIICGTSLVA-LVHNAEKYRDPNWKVAASFVTMPALKMNKTTEFQCTELLETVASRKINHVASSHLVFDMKHKASGRNDFRCIIPGTNGVQYRMKILWDKAVKSGRMEPTSFVNCVSTTPAKLANIYPHKGTISIGSDADIIVWKGDSV----SHSNFEAGDINVFEDVICHSGPKYVIVNGIVVLDHEGNFTASKGSGQIVSPSLETMNSYFQKQLINYKLSHEVEKKIAREPYDGPVIDPSADNKEEKHVLYSHMVNNDVYKRGGPAEDKKEALPPGQRVIRTSVKTAQPPGGSA 1813
LLIK GT++N D + +DVL+ +G+IV IA +I+ + E +DAT V+PGG+D T+ G ++ +++ GT+AA+ GGTT +++ + K ESL Y+ + ++VC+ + + + I E + ++ + + G V+ DEE Y + C L VHAEN ++A + LL+ G+TGPEGH SRPE++E EA FR T+A CP++ V +K + I ++K + ++ G + A L + Y + +W AA +V P L + +T + L++ +A+ +++ A+ + FD + K+ G++DF I G NGV+ RM ++WDK V +G ++P FV ST AK+ N YP KG I++GSDADI++W ++ ++ A D N+FE + H P+ I G V + G +GSGQ + + ++ + + N K + E KI R PY +PSA L + N ++ V++ V+ A PPGG++
Sbjct: 3 LLIKNGTIVNDDAIFKSDVLVLDGRIVEIAPSIQPTPGLEVVDATDRLVIPGGIDPHTHMQLPFMGEIAKDDFHRGTEAAVAGGTTMIIDFVIPTKGESLLVAYDRWRGWADPKVVCDYGLSMAITSWGPEIAKEMEIVTGAEYGINSFKFFLAYAGVFMVR--DEEFYQGMIQCAKLRALARVHAENGSVIAERCEHLLSSGITGPEGHTQSRPEELEAEATFRACTMASQANCPLYVVHVMSKGAAAAIAHHRKKGA--VVFGEPIAAGLATDGSHYYNEDWLHAARYVMSPPLSRDPSTP---SALMKLLAAGELHLTATDNCTFDCQQKSLGKDDFTKIPNGVNGVEDRMSVVWDKGVHAGIIDPMRFVAVTSTMAAKIFNCYPQKGRIAVGSDADIVIWNANATRTISKDTHHHAIDFNIFEGMQVHGVPEITISRGRTVWAN-GQLKTVQGSGQFIPLAPDSQIVF--SAVDNRKKAME-PVKIDRIPY-----EPSA--------LQTPDANANI-------------------VVKAPVRAAIPPGGAS 516
BLAST of Dihydropyrimidinase vs. Ensembl Celegans
Match: dhp-1 (Dihydropyrimidinase 1 [Source:UniProtKB/Swiss-Prot;Acc:Q21773]) HSP 1 Score: 239.965 bits (611), Expect = 2.192e-71 Identity = 152/471 (32.27%), Postives = 241/471 (51.17%), Query Frame = 2
Query: 161 LLIKCGTVINHDCTYDADVLIENGKIVNIAKNIED-SLAECIDATGCFVLPGGVDAETNFAAKRGGIVSPENYFSGTKAAIYGGTTTVVN--CLEIMKDESLKEKYEMEKDIISKEIVCN----LAIQLCLPEVNEAIKSEFNELLQSKSVVPLVRLSTVDKGCHCVKIDDEELYDALCWCRDNSVLPTVHAENDKMVAILEKELLADGVTGPEGHYLSRPEKVEDEAVFRVLTIAEMVKCPIHFGKVYAKSSLDKIMDWQRKSSNTIICGTSLVA-LVHNAEKYRDPNWKVAASFVTMPALKMNKTTEFQCTELLETVASRKINHVASSHLVFDMKHKASGRNDFRCIIPGTNGVQYRMKILWDKAVKSGRMEPTSFVNCVSTTPAKLANIYPHKGTISIGSDADIIVWKGDSVS-------HSNFEAGDINVFEDVICHSGPKYVIVNGIVVLDHEGNFTASKGSGQIV 1528
L+IK GTV+N D + ADVL+ NG IV ++ NI E IDAT V+PGG+D T+ G V+ +++ GT+AA+ GGTT +++ C + ESL Y + ++ C+ +AI + PE E + + S + + + D+EL+ + C L VH EN ++ E +LLA GVTGPEGH SRPE++E EA R +A CP++ V K + I ++ +I+ G + A L + Y + +W AA +V P L + TT L++ +A+ +++ + + +D + K+ G+ +F I G NGV+ RM ++W+K V SG ++P +V+ S+T AK+ NIYP KG I++GSDADI+++ ++ H N D N+FE + CH + I G +V H G GSG+ +
Sbjct: 5 LVIKNGTVVNEDGMFKADVLVRNGIIVEVSPNITALPDTEVIDATDRLVIPGGIDPHTHMQMPYMGEVTKDDFLKGTEAAVAGGTTMIIDFCCPDHRNGESLIAGYNRWRSWADPKVCCDYGLSVAITMWRPETAEQMAIITSPEFGVNSFKFYMAYENT------LMVRDDELFRGMQECAKLRALARVHCENGSVIKEKEIDLLAKGVTGPEGHTQSRPEEIEAEATNRACVLAAQANCPVYIVHVMTKGAASAIS--HHRAQGSIVFGEPIAAGLALDGSHYYNEDWLHAARYVMSPPLSRDPTTP---ELLMKLLAAGELHLTGTDNCTYDCRQKSLGKGNFTKIPNGINGVEDRMSVVWEKGVHSGIIDPMRYVSITSSTAAKIFNIYPRKGRIAVGSDADIVIFNPNATRTISKDTHHHNL---DFNIFEGINCHGVAEVTISRGRIVWAH-GKLQTVPGSGKFI 460
BLAST of Dihydropyrimidinase vs. Ensembl Celegans
Match: dhp-1 (Dihydropyrimidinase 1 [Source:UniProtKB/Swiss-Prot;Acc:Q21773]) HSP 1 Score: 239.965 bits (611), Expect = 2.192e-71 Identity = 152/471 (32.27%), Postives = 241/471 (51.17%), Query Frame = 2
Query: 161 LLIKCGTVINHDCTYDADVLIENGKIVNIAKNIED-SLAECIDATGCFVLPGGVDAETNFAAKRGGIVSPENYFSGTKAAIYGGTTTVVN--CLEIMKDESLKEKYEMEKDIISKEIVCN----LAIQLCLPEVNEAIKSEFNELLQSKSVVPLVRLSTVDKGCHCVKIDDEELYDALCWCRDNSVLPTVHAENDKMVAILEKELLADGVTGPEGHYLSRPEKVEDEAVFRVLTIAEMVKCPIHFGKVYAKSSLDKIMDWQRKSSNTIICGTSLVA-LVHNAEKYRDPNWKVAASFVTMPALKMNKTTEFQCTELLETVASRKINHVASSHLVFDMKHKASGRNDFRCIIPGTNGVQYRMKILWDKAVKSGRMEPTSFVNCVSTTPAKLANIYPHKGTISIGSDADIIVWKGDSVS-------HSNFEAGDINVFEDVICHSGPKYVIVNGIVVLDHEGNFTASKGSGQIV 1528
L+IK GTV+N D + ADVL+ NG IV ++ NI E IDAT V+PGG+D T+ G V+ +++ GT+AA+ GGTT +++ C + ESL Y + ++ C+ +AI + PE E + + S + + + D+EL+ + C L VH EN ++ E +LLA GVTGPEGH SRPE++E EA R +A CP++ V K + I ++ +I+ G + A L + Y + +W AA +V P L + TT L++ +A+ +++ + + +D + K+ G+ +F I G NGV+ RM ++W+K V SG ++P +V+ S+T AK+ NIYP KG I++GSDADI+++ ++ H N D N+FE + CH + I G +V H G GSG+ +
Sbjct: 5 LVIKNGTVVNEDGMFKADVLVRNGIIVEVSPNITALPDTEVIDATDRLVIPGGIDPHTHMQMPYMGEVTKDDFLKGTEAAVAGGTTMIIDFCCPDHRNGESLIAGYNRWRSWADPKVCCDYGLSVAITMWRPETAEQMAIITSPEFGVNSFKFYMAYENT------LMVRDDELFRGMQECAKLRALARVHCENGSVIKEKEIDLLAKGVTGPEGHTQSRPEEIEAEATNRACVLAAQANCPVYIVHVMTKGAASAIS--HHRAQGSIVFGEPIAAGLALDGSHYYNEDWLHAARYVMSPPLSRDPTTP---ELLMKLLAAGELHLTGTDNCTYDCRQKSLGKGNFTKIPNGINGVEDRMSVVWEKGVHSGIIDPMRYVSITSSTAAKIFNIYPRKGRIAVGSDADIVIFNPNATRTISKDTHHHNL---DFNIFEGINCHGVAEVTISRGRIVWAH-GKLQTVPGSGKFI 460
BLAST of Dihydropyrimidinase vs. Ensembl Celegans
Match: dhp-1 (Dihydropyrimidinase 1 [Source:UniProtKB/Swiss-Prot;Acc:Q21773]) HSP 1 Score: 239.965 bits (611), Expect = 2.192e-71 Identity = 152/471 (32.27%), Postives = 241/471 (51.17%), Query Frame = 2
Query: 161 LLIKCGTVINHDCTYDADVLIENGKIVNIAKNIED-SLAECIDATGCFVLPGGVDAETNFAAKRGGIVSPENYFSGTKAAIYGGTTTVVN--CLEIMKDESLKEKYEMEKDIISKEIVCN----LAIQLCLPEVNEAIKSEFNELLQSKSVVPLVRLSTVDKGCHCVKIDDEELYDALCWCRDNSVLPTVHAENDKMVAILEKELLADGVTGPEGHYLSRPEKVEDEAVFRVLTIAEMVKCPIHFGKVYAKSSLDKIMDWQRKSSNTIICGTSLVA-LVHNAEKYRDPNWKVAASFVTMPALKMNKTTEFQCTELLETVASRKINHVASSHLVFDMKHKASGRNDFRCIIPGTNGVQYRMKILWDKAVKSGRMEPTSFVNCVSTTPAKLANIYPHKGTISIGSDADIIVWKGDSVS-------HSNFEAGDINVFEDVICHSGPKYVIVNGIVVLDHEGNFTASKGSGQIV 1528
L+IK GTV+N D + ADVL+ NG IV ++ NI E IDAT V+PGG+D T+ G V+ +++ GT+AA+ GGTT +++ C + ESL Y + ++ C+ +AI + PE E + + S + + + D+EL+ + C L VH EN ++ E +LLA GVTGPEGH SRPE++E EA R +A CP++ V K + I ++ +I+ G + A L + Y + +W AA +V P L + TT L++ +A+ +++ + + +D + K+ G+ +F I G NGV+ RM ++W+K V SG ++P +V+ S+T AK+ NIYP KG I++GSDADI+++ ++ H N D N+FE + CH + I G +V H G GSG+ +
Sbjct: 5 LVIKNGTVVNEDGMFKADVLVRNGIIVEVSPNITALPDTEVIDATDRLVIPGGIDPHTHMQMPYMGEVTKDDFLKGTEAAVAGGTTMIIDFCCPDHRNGESLIAGYNRWRSWADPKVCCDYGLSVAITMWRPETAEQMAIITSPEFGVNSFKFYMAYENT------LMVRDDELFRGMQECAKLRALARVHCENGSVIKEKEIDLLAKGVTGPEGHTQSRPEEIEAEATNRACVLAAQANCPVYIVHVMTKGAASAIS--HHRAQGSIVFGEPIAAGLALDGSHYYNEDWLHAARYVMSPPLSRDPTTP---ELLMKLLAAGELHLTGTDNCTYDCRQKSLGKGNFTKIPNGINGVEDRMSVVWEKGVHSGIIDPMRYVSITSSTAAKIFNIYPRKGRIAVGSDADIVIFNPNATRTISKDTHHHNL---DFNIFEGINCHGVAEVTISRGRIVWAH-GKLQTVPGSGKFI 460
BLAST of Dihydropyrimidinase vs. Ensembl Celegans
Match: unc-33 (pep chromosome:WBcel235:IV:3518147:3525572:1 gene:WBGene00006769.1 transcript:Y37E11C.1b.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:unc-33) HSP 1 Score: 176.022 bits (445), Expect = 1.169e-46 Identity = 119/404 (29.46%), Postives = 204/404 (50.50%), Query Frame = 2
Query: 161 LLIKCGTVINHDCTYDADVLIENGKIVNIAKNIE-DSLAECIDATGCFVLPGGVDAETNFAAKRGGIVSPENYFSGTKAAIYGGTTTVVNCLEIMKDESLKEKYEMEKDIISKE-IVCNLAIQLCLPEVNEAIKSEFNELLQSKSVVPLVRLSTVDKGCHCVKIDDEELYDALCWCRDNSVLPTVHAENDKMVAILEKELLADGVTGPEGHYLSRPEKVEDEAVFRVLTIAEMVKCPIHFGKVYAKSSLDKIMDWQRKSSNTIICGTSLVALVHNAEKYRDPNWKVAASFVTMPALKMNKTTEFQCTELLETVASRKINHVASSHLVFDMKHKASGRNDFRCIIPGTNGVQYRMKILWDKAVKSGRMEPTSFVNCVSTTPAKLANIYPHKGTISIGSDADIIVW 1366
LL+K ++N D + AD+LIE+G I N+A N+E AE +DA G LP G+D T S ++ +G K+AI GGT T+V + ES+ + K+ + K I C++A+ + + + E E +EL++++ + V V + D++L + + L V EN +VA+LEK++L GVTGPEG SRPE +E + V V + + CPI +V + SL I + R S + A+ + + + A++ +T L+ ++ ++++ + S H + + + + DF G+ G + RM ++W++AV+SGR++ FV ST AK+ N+YP KG I++G+DAD+++W
Sbjct: 160 LLVKNAQIVNDDAIFVADILIEDGIIQNVAPNLEAPEGAEVLDAAGKLALPAGIDVYTQVTDS-----SVDDLSTGCKSAIAGGTGTIVEVVRPRGAESVVSAVKRVKNQLEKSGISCHVALSVAITDFCE---QEMSELVKNEGINSFV--------LDGVSLTDDKLLELFEHVKRLGALIRVVPENKSIVAMLEKKMLKLGVTGPEGFPQSRPESLEADRVSGVCVLGNLASCPISIVQVSSADSLAAI-EKARASGALAHAEIASAAVTADGSALFSQDLRFASAHLTDVPLRRGAPDR-----MIGALSTQPLVVCTSGHRPVNSATRVAAK-DFAIAQKGSTGAEERMAVVWERAVRSGRIDAMRFVAVTSTNAAKMFNMYPKKGRIAVGADADLVIW 540
BLAST of Dihydropyrimidinase vs. Ensembl Fly
Match: CRMP (gene:FBgn0023023 transcript:FBtr0114453) HSP 1 Score: 258.07 bits (658), Expect = 4.439e-77 Identity = 153/474 (32.28%), Postives = 261/474 (55.06%), Query Frame = 2
Query: 134 LFMSETQKKLLIKCGTVINHDCTYDADVLIENGKIVNIAKNIEDSL---AECIDATGCFVLPGGVDAETNFAAKRGGIVSPENYFSGTKAAIYGGTTTVVNCLEIMKDESLKEKYEMEKDIISKEIVCNLAIQLCLPEVNEAIKSEFNELLQSKSVVPLVRLSTVDKGCHCVKIDDEELYDALCWCRDNSVLPTVHAENDKMVAILEKELLADGVTGPEGHYLSRPEKVEDEAVFRVLTIAEMVKCPIHFGKVYAKSSLDKIMDWQRKSSNTIICGTSLVA-LVHNAEKYRDPNWKVAASFVTMPALKMNKTT-EFQCTELLETVASRKINHVASSHLVFDMKHKASGRNDFRCIIPGTNGVQYRMKILWDKAVKSGRMEPTSFVNCVSTTPAKLANIYPHKGTISIGSDADIIVWKGDSV----SHSNFEAGDINVFEDVICHSGPKYVIVNGIVVLDHEGNFTASKGSGQIV 1528
+ + Q ++ IK G ++NHD ++ ADV IE+G I + + E ++ IDA+G ++PGG+D T+ GG V+ ++++ GTKAA+ GGTT +++ + K ES+ E Y+ + ++ C+ + + + ++++ E L + V + KG + +++D +L D R + + VHAEN ++A + LLA+G+ GPEGH LSRPE+VE EAV R +A CP++ V +KS+ ++ + + I G +L A L +A + + A+ V P L+ +KTT EF L++ +A+ + S + F+ +HKA G+ DF I G NGV+ RM ++W+K V +G ++P FV ST AK+ NIYP KG I++GSDADI++W ++ ++ A D N+FE + H ++V+V G + + GN ++G G+ +
Sbjct: 13 IHLQSAQNRVYIKNGEIVNHDKSFKADVYIEDGIIKFVGPSSEITIPGGVRTIDASGLMIIPGGIDPHTHMQLPFGGAVAVDDFYHGTKAAVAGGTTMIIDFVLPNKHESMIEAYDKWRSWADPKVCCDYGLHVGITWWSKSVSEEIGILCKELGVNSF-KTFMAYKGLY--QLNDSDLLDVFERIRHLNGVAMVHAENGDIIAKNTQRLLAEGINGPEGHELSRPEEVEAEAVHRACVLAHQADCPLYVVHVMSKSAGIELARARHRYRGRYIMGETLAAALGTDATCCQHLGFDAEAAHVLSPPLRPDKTTPEF----LMKLLANDDLQLTGSDNCTFNKEHKALGKGDFTKIPNGVNGVEDRMSLVWEKGVHAGLLDPCRFVAVTSTNAAKIFNIYPQKGRIAVGSDADIVIWNPNATRTISKDTHHHACDFNIFEGMTVHGVCEFVLVRGRICAE-RGNVRVAEGFGRFI 478
BLAST of Dihydropyrimidinase vs. Ensembl Fly
Match: CRMP (gene:FBgn0023023 transcript:FBtr0089686) HSP 1 Score: 248.054 bits (632), Expect = 2.491e-73 Identity = 147/472 (31.14%), Postives = 258/472 (54.66%), Query Frame = 2
Query: 134 LFMSETQKKLLIKCGTVINHDCTYDADVLIENGKIVNIAKNIEDSL---AECIDATGCFVLPGGVDAETNFAAKRGGIVSPENYFSGTKAAIYGGTTTVVNCLEIMKDESLKEKYEMEKDIISKEIVCNLAIQLCLPEVNEAIKSEFNELLQSKSVVPLVRLSTVDKGCHCVKIDDEELYDALCWCRDNSVLPTVHAENDKMVAILEKELLADGVTGPEGHYLSRPEKVEDEAVFRVLTIAEMVKCPIHFGKVYAKSSLDKIMDWQRKSSNTIICGTSLVALVHNAEKYRDPNWKVAASFVTMPALKMNKTTEFQCTELLETVASRKINHVASSHLVFDMKHKASGRNDFRCIIPGTNGVQYRMKILWDKAVKSGRMEPTSFVNCVSTTPAKLANIYPHKGTISIGSDADIIVWKGDSV----SHSNFEAGDINVFEDVICHSGPKYVIVNGIVVLDHEGNFTASKGSGQIV 1528
+ + Q ++ IK G ++NHD ++ ADV IE+G I + + E ++ IDA+G ++PGG+D T+ GG V+ ++++ GTKAA+ GGTT +++ + K ES+ E Y+ + ++ C+ + + + ++++ E L + V + KG + +++D +L D R + + VHAEN ++A + LLA+G+ GPEGH LSRPE+VE EAV R +A +K P+ + +KSS + + +R S + G +L + + + ++ A +T P ++ + T Q L++++A + S + F+ +HKA G+ DF I G NGV+ RM ++W+K V +G ++P FV ST AK+ NIYP KG I++GSDADI++W ++ ++ A D N+FE + H ++V+V G + + GN ++G G+ +
Sbjct: 13 IHLQSAQNRVYIKNGEIVNHDKSFKADVYIEDGIIKFVGPSSEITIPGGVRTIDASGLMIIPGGIDPHTHMQLPFGGAVAVDDFYHGTKAAVAGGTTMIIDFVLPNKHESMIEAYDKWRSWADPKVCCDYGLHVGITWWSKSVSEEIGILCKELGVNSF-KTFMAYKGLY--QLNDSDLLDVFERIRHLNGVAMVHAENGDIIAKNTQRLLAEGINGPEGHELSRPEEVEAEAVHRACVLAHQMKTPLFVSGLTSKSSAELVGRARR--SGYCVFGETLASSLGRSMSAVPKGDRIYA--ITSPPIRESAETPRQ---LMKSLAYDDLQLTGSDNCTFNKEHKALGKGDFTKIPNGVNGVEDRMSLVWEKGVHAGLLDPCRFVAVTSTNAAKIFNIYPQKGRIAVGSDADIVIWNPNATRTISKDTHHHACDFNIFEGMTVHGVCEFVLVRGRICAE-RGNVRVAEGFGRFI 473
BLAST of Dihydropyrimidinase vs. Ensembl Fly
Match: CRMP (gene:FBgn0023023 transcript:FBtr0089685) HSP 1 Score: 158.688 bits (400), Expect = 4.400e-43 Identity = 98/321 (30.53%), Postives = 171/321 (53.27%), Query Frame = 2
Query: 134 LFMSETQKKLLIKCGTVINHDCTYDADVLIENGKIVNIAKNIEDSL---AECIDATGCFVLPGGVDAETNFAAKRGGIVSPENYFSGTKAAIYGGTTTVVNCLEIMKDESLKEKYEMEKDIISKEIVCNLAIQLCLPEVNEAIKSEFNELLQSKSVVPLVRLSTVDKGCHCVKIDDEELYDALCWCRDNSVLPTVHAENDKMVAILEKELLADGVTGPEGHYLSRPEKVEDEAVFRVLTIAEMVKCPIHFGKVYAKSSLDKIMDWQRKSSNTIICGTSL-VALVHNAEKYRDPNWKVAASFVTMPALKMNKTTEFQCTELL 1084
+ + Q ++ IK G ++NHD ++ ADV IE+G I + + E ++ IDA+G ++PGG+D T+ GG V+ ++++ GTKAA+ GGTT +++ + K ES+ E Y+ + ++ C+ + + + ++++ E L + V + KG + +++D +L D R + + VHAEN ++A + LLA+G+ GPEGH LSRPE+VE EAV R +A CP++ V +KS+ ++ + + I G +L AL +A + + A+ V P L+ +KTT +LL
Sbjct: 13 IHLQSAQNRVYIKNGEIVNHDKSFKADVYIEDGIIKFVGPSSEITIPGGVRTIDASGLMIIPGGIDPHTHMQLPFGGAVAVDDFYHGTKAAVAGGTTMIIDFVLPNKHESMIEAYDKWRSWADPKVCCDYGLHVGITWWSKSVSEEIGILCKELGVNSF-KTFMAYKGLY--QLNDSDLLDVFERIRHLNGVAMVHAENGDIIAKNTQRLLAEGINGPEGHELSRPEEVEAEAVHRACVLAHQADCPLYVVHVMSKSAGIELARARHRYRGRYIMGETLAAALGTDATCCQHLGFDAEAAHVLSPPLRPDKTTPEFLMKLL 330
BLAST of Dihydropyrimidinase vs. Ensembl Zebrafish
Match: crmp1 (collapsin response mediator protein 1 [Source:ZFIN;Acc:ZDB-GENE-050720-1]) HSP 1 Score: 309.686 bits (792), Expect = 1.092e-96 Identity = 179/511 (35.03%), Postives = 281/511 (54.99%), Query Frame = 2
Query: 149 TQKKLLIKCGTVINHDCTYDADVLIENGKIVNIAKN-IEDSLAECIDATGCFVLPGGVDAETNFAAKRGGIVSPENYFSGTKAAIYGGTTTVVNCLEIMKDESLKEKYEMEKDIISKEIVCNLAIQLCLPEVNEAIKSEFNELLQSKSVVPLVRLSTVDKGCHCVKIDDEELYDALCWCRDNSVLPTVHAENDKMVAILEKELLADGVTGPEGHYLSRPEKVEDEAVFRVLTIAEMVKCPIHFGKVYAKSSLDKIMDWQRKSSNTIICGTSLVA-LVHNAEKYRDPNWKVAASFVTMPALKMNKTTEFQCTELLETVASRKINHVASSHLVFDMKHKASGRNDFRCIIPGTNGVQYRMKILWDKAVKSGRMEPTSFVNCVSTTPAKLANIYPHKGTISIGSDADIIVWKGDSV----SHSNFEAGDINVFEDVICHSGPKYVIVNGIVVLDHEGNFTASKGSGQIVSPSLETMNSYFQKQLINYKLSHEVEKKIAREPYDGPVIDPSADNK 1663
T ++LLIK G V+N D + ADV +E+G I + +N I + I+A GC V+PGG+D T G ++++ GTKAA+ GGTT +++ + + L E +E ++ K+ C+ ++ + +P +E +K E +L+Q K + ++ KG + ++ D +LY+A + ++ + VHAEN ++A + ++L G+ GPEGH LSRPE++E EAVFR +TI V CP++ KV +KS+ + + ++K S ++ G + A L + Y NW AA++VT P L + TT LL A + V S H + KA G+++F I GTNGV+ RM +WDKAV G+M+ FV ST AK+ N+YP KG I++GSDADI++W D + + S A + N+FE + C GP +V+ G VV + EG +G+G+ +S F Q I Y+ + ++R YDGPV D A K
Sbjct: 16 TSERLLIKGGRVVNDDQSLYADVYVEDGIIKQVGENLIVPGGVKVIEANGCMVIPGGIDVNTCLHKPYLGTPPVDDFYQGTKAALAGGTTMIIDHVTPQPGDGLLEAFEKWQEAADKKSCCDYSLHVDIPHWHEGVKEELEQLVQEKGINSF-QVYMAYKGLY--QMPDSQLYEAFSFLKELGAVVLVHAENGDLIAQEQSKILGMGIIGPEGHPLSRPEELEAEAVFRAITIGNRVNCPVYITKVMSKSAAETVAIARKKGS--VVFGEPITASLATDGSHYWSKNWAKAAAYVTSPPLSPDPTTPEHLHSLL---ACGDLQVVGSGHCAYSTSQKAIGKDNFTLIPEGTNGVEERMGFVWDKAVAMGKMDENQFVAVTSTNAAKIFNLYPRKGRIAVGSDADIVIWDPDKIKTITAKSQQSALEYNIFEGMDCRGGPLHVVSQGRVVFE-EGKLQVQQGTGRFIS---RKPFPDFAYQRIKYRNKIMNMQGVSRGMYDGPVYDVPATPK 514
BLAST of Dihydropyrimidinase vs. Ensembl Zebrafish
Match: dpysl3 (dihydropyrimidinase like 3 [Source:NCBI gene;Acc:553166]) HSP 1 Score: 298.516 bits (763), Expect = 1.934e-92 Identity = 187/572 (32.69%), Postives = 301/572 (52.62%), Query Frame = 2
Query: 149 TQKKLLIKCGTVINHDCTYDADVLIENGKIVNIAKN-IEDSLAECIDATGCFVLPGGVDAETNFAAKRGGIVSPENYFSGTKAAIYGGTTTVVNCLEIMKDESLKEKYEMEKDIISKEIVCNLAIQLCLPEVNEAIKSEFNELLQSKSVVPL-VRLSTVDKGCHCVKIDDEELYDALCWCRDNSVLPTVHAENDKMVAILEKELLADGVTGPEGHYLSRPEKVEDEAVFRVLTIAEMVKCPIHFGKVYAKSSLDKIMDWQRKSSNTIICGTSLVALVHNAEKYRDPNWKVAASFVTMPALKMNKTTEFQCTELLETVASRKINHVASSHLVFDMKHKASGRNDFRCIIPGTNGVQYRMKILWDKAVKSGRMEPTSFVNCVSTTPAKLANIYPHKGTISIGSDADIIVWKGDSV----SHSNFEAGDINVFEDVICHSGPKYVIVNGIVVLDHEGNFTASKGSGQIV--SPSLETMNSYFQKQLINYKLSHEVEKKIAREPYDGPVID---------PSADNKEEKHVLYSHMVNNDVYKRGGPAEDKKEALPPGQRVIRTSVKTAQPPGGSA 1813
T ++LLIK G ++N D ++ AD+ +E+G I I N I + I+A G V+PGG+D T+ G + +++ GTKAA+ GGTT +V+ + SL E ++ ++ C+ ++ + + N+++K E L++ K V V ++ D ++ + ELY+ + ++ + VHAEN +++A + +L G+TGPEGH LSRPE++E EAVFR +TIA CP++ +V +KS+ D I+ RK N + +L + Y NW AASFVT P L + TT LL AS ++ V S+H F + KA G++DF I G NG + RM I+WDKAV +G+M+ FV ST AK+ N+YP KG I++GSD+D+++W D+V + ++ A + NVFE + P V+ G +VL+ +GN A+ G+G+ + SP + F + + + + K + R YDGPV + PSA + + ++ + GP E P G+R++ PPGG +
Sbjct: 13 TSERLLIKGGRIVNDDQSFYADIYMEDGVIKQIGDNLIVPGGVKTIEANGKMVIPGGIDIHTHLQMPFRGTTTADDFTQGTKAALAGGTTMIVDHVIPEPGCSLLEAFDRWSKWADEKACCDYSLHVDITHWNDSVKQEVETLIKEKGVNSFQVYMAFKD----LYQMSNTELYEVFTFLGEHGGIAQVHAENGEIIAEEQARMLEMGITGPEGHVLSRPEELEAEAVFRAVTIASQTNCPLYVTRVMSKSAAD-IISQARKKGNVVFGEPITASLGTDGTHYWSKNWAKAASFVTSPPLSPDPTTPDYLNTLL---ASGDLSVVGSAHCTFSVAQKAIGKDDFTQIPEGVNGAEERMSIIWDKAVVTGKMDENMFVAVTSTNAAKILNLYPRKGRIAVGSDSDLVIWDTDAVRTITAKTHHSAAEYNVFEGMELRGAPMLVVCQGKIVLE-DGNLHATSGTGRFIPCSPFPD-----FAYKRVKARKQLAILKAVPRGMYDGPVSEFSPMSRGGTPSASTRTSPTKVPVRNLHQSGFTLSGPEE--APIRPAGRRIV-------VPPGGRS 561
BLAST of Dihydropyrimidinase vs. Ensembl Zebrafish
Match: dpysl5a (dihydropyrimidinase like 5a [Source:ZFIN;Acc:ZDB-GENE-030131-3136]) HSP 1 Score: 291.197 bits (744), Expect = 1.106e-89 Identity = 188/573 (32.81%), Postives = 294/573 (51.31%), Query Frame = 2
Query: 143 SETQKKLLIKCGTVINHDCTYDADVLIENGKIVNIAKNIE-DSLAECIDATGCFVLPGGVDAETNFAAKRGGIVSPENYFSGTKAAIYGGTTTVVNCLEIMKDESLKEKYEMEKDIISKEIVCNLAIQLCLPEVNEAIKSEFNELLQSKSVVPLVRLSTVDKGCHCVKIDDEELYDALCWCRDNSVLPTVHAENDKMVAILEKELLADGVTGPEGHYLSRPEKVEDEAVFRVLTIAEMVKCPIHFGKVYAKSSLDKIMDWQRKSSNTIICG-TSLVALVHNAEKYRDPNWKVAASFVTMPALKMNKTTEFQCTELLETVASRKINHVASSHLVFDMKHKASGRNDFRCIIPGTNGVQYRMKILWDKAVKSGRMEPTSFVNCVSTTPAKLANIYPHKGTISIGSDADIIVWKGDSVS----HSNFEAGDINVFEDVICHSGPKYVIVNGIVVLDHEGNFTASKGSGQIVSPSLETMNSYFQKQLINYKLSHEVEKKIAREPYDGPVIDPSADNKEEKHVLYSHMVNNDVYKRGGPAEDKKEALPPGQRVI------RTSVKTAQPPGGSAQASW 1825
S ++LIK G V+N D T +ADV IENG I + K + A+ IDATG VLPGG+D + + ++++SGTKAA+ GGTT V+ + K+ESL + YE + + C+ A+ + + +++ L++ K V ++ K + ++ D EL+ AL C+D + VHAEN ++VA +E L G++GPEG +SRPE++E EAV R +TIA CPI+ V + S+ D + K ++ G T+ V N +Y +W AA+FVT+P L+++ T LL + + +N V S H F K KA G++DF I G GVQ RM ++W++ V G+M+ FV S+ AK+ N+YP KG I G+DAD++VW +S + ++ GD+N++E++ CH P I G VV ++ G FT ++GSG+ L T Y K+++ + + K + R PY G V K++ M + GG + + + I R S + PPGG + W
Sbjct: 4 SSATVRILIKGGKVVNDDFTQEADVYIENGIIQQVGKELMIPGGAKVIDATGKLVLPGGIDTSVHLNESFMNGTTADDFYSGTKAALAGGTTMVIGHVLPEKNESLLDAYEKARSHADAKACCDYALHMGVTWWGPKARAQMETLVRDKGVNSF-QMYMAYKDMYMLR--DSELFQALQNCKDIGAVARVHAENGELVAEGAREALDLGISGPEGIEISRPEELEAEAVHRAITIANRAHCPIYLVNVSSMSAGDVLA--SAKMQGKVVHGETTTAHAVLNGMQYYHQDWAHAAAFVTVPPLRLDPNTP---NYLLSLLGNDTLNVVTSDHRPFTTKQKAMGKDDFTKIPHGVPGVQDRMSVMWERGVVGGKMDENRFVAVTSSNAAKIYNLYPRKGRIIPGADADVVVWDPESTRTISVTTQWQGGDVNLYENLRCHGVPLVTISRGRVVYEN-GIFTCAEGSGKFY--PLRTFPDYLYKKMVQREKCQAL-KGVERTPYTGDVAAVQNSGKKDLGPADGDMNPRPCTRHGGVRDLHESSFSLSGAQIDDNVPKRASARILAPPGGRSSGIW 564
BLAST of Dihydropyrimidinase vs. Ensembl Zebrafish
Match: dpysl5a (dihydropyrimidinase like 5a [Source:ZFIN;Acc:ZDB-GENE-030131-3136]) HSP 1 Score: 291.197 bits (744), Expect = 1.106e-89 Identity = 188/573 (32.81%), Postives = 294/573 (51.31%), Query Frame = 2
Query: 143 SETQKKLLIKCGTVINHDCTYDADVLIENGKIVNIAKNIE-DSLAECIDATGCFVLPGGVDAETNFAAKRGGIVSPENYFSGTKAAIYGGTTTVVNCLEIMKDESLKEKYEMEKDIISKEIVCNLAIQLCLPEVNEAIKSEFNELLQSKSVVPLVRLSTVDKGCHCVKIDDEELYDALCWCRDNSVLPTVHAENDKMVAILEKELLADGVTGPEGHYLSRPEKVEDEAVFRVLTIAEMVKCPIHFGKVYAKSSLDKIMDWQRKSSNTIICG-TSLVALVHNAEKYRDPNWKVAASFVTMPALKMNKTTEFQCTELLETVASRKINHVASSHLVFDMKHKASGRNDFRCIIPGTNGVQYRMKILWDKAVKSGRMEPTSFVNCVSTTPAKLANIYPHKGTISIGSDADIIVWKGDSVS----HSNFEAGDINVFEDVICHSGPKYVIVNGIVVLDHEGNFTASKGSGQIVSPSLETMNSYFQKQLINYKLSHEVEKKIAREPYDGPVIDPSADNKEEKHVLYSHMVNNDVYKRGGPAEDKKEALPPGQRVI------RTSVKTAQPPGGSAQASW 1825
S ++LIK G V+N D T +ADV IENG I + K + A+ IDATG VLPGG+D + + ++++SGTKAA+ GGTT V+ + K+ESL + YE + + C+ A+ + + +++ L++ K V ++ K + ++ D EL+ AL C+D + VHAEN ++VA +E L G++GPEG +SRPE++E EAV R +TIA CPI+ V + S+ D + K ++ G T+ V N +Y +W AA+FVT+P L+++ T LL + + +N V S H F K KA G++DF I G GVQ RM ++W++ V G+M+ FV S+ AK+ N+YP KG I G+DAD++VW +S + ++ GD+N++E++ CH P I G VV ++ G FT ++GSG+ L T Y K+++ + + K + R PY G V K++ M + GG + + + I R S + PPGG + W
Sbjct: 4 SSATVRILIKGGKVVNDDFTQEADVYIENGIIQQVGKELMIPGGAKVIDATGKLVLPGGIDTSVHLNESFMNGTTADDFYSGTKAALAGGTTMVIGHVLPEKNESLLDAYEKARSHADAKACCDYALHMGVTWWGPKARAQMETLVRDKGVNSF-QMYMAYKDMYMLR--DSELFQALQNCKDIGAVARVHAENGELVAEGAREALDLGISGPEGIEISRPEELEAEAVHRAITIANRAHCPIYLVNVSSMSAGDVLA--SAKMQGKVVHGETTTAHAVLNGMQYYHQDWAHAAAFVTVPPLRLDPNTP---NYLLSLLGNDTLNVVTSDHRPFTTKQKAMGKDDFTKIPHGVPGVQDRMSVMWERGVVGGKMDENRFVAVTSSNAAKIYNLYPRKGRIIPGADADVVVWDPESTRTISVTTQWQGGDVNLYENLRCHGVPLVTISRGRVVYEN-GIFTCAEGSGKFY--PLRTFPDYLYKKMVQREKCQAL-KGVERTPYTGDVAAVQNSGKKDLGPADGDMNPRPCTRHGGVRDLHESSFSLSGAQIDDNVPKRASARILAPPGGRSSGIW 564
BLAST of Dihydropyrimidinase vs. Ensembl Zebrafish
Match: dpysl5a (dihydropyrimidinase like 5a [Source:ZFIN;Acc:ZDB-GENE-030131-3136]) HSP 1 Score: 282.722 bits (722), Expect = 2.336e-86 Identity = 189/585 (32.31%), Postives = 295/585 (50.43%), Query Frame = 2
Query: 143 SETQKKLLIKCGTVINHDCTYDADVLIENGKIVNIAKNIE-DSLAECIDATGCFVLPGGVDAETNFAAKRGGIVSPENYFSGTKAAIYGGTTTVVNCLEIMKDESLKEKYEMEKDIISKEIVCNLAIQLCLPEVNEAIKSEFNELLQSKSVVPLVRLSTVDKGCHCVKIDDEELYDALCWCRDNSVLPTVHAENDKMVA--------IL----EKELLADGVTGPEGHYLSRPEKVEDEAVFRVLTIAEMVKCPIHFGKVYAKSSLDKIMDWQRKSSNTIICGTSLVA-LVHNAEKYRDPNWKVAASFVTMPALKMNKTTEFQCTELLETVASRKINHVASSHLVFDMKHKASGRNDFRCIIPGTNGVQYRMKILWDKAVKSGRMEPTSFVNCVSTTPAKLANIYPHKGTISIGSDADIIVWKGDSVS----HSNFEAGDINVFEDVICHSGPKYVIVNGIVVLDHEGNFTASKGSGQIVSPSLETMNSYFQKQLINYKLSHEVEKKIAREPYDGPVIDPSADNKEEKHVLYSHMVNNDVYKRGGPAEDKKEALPPGQRVI------RTSVKTAQPPGGSAQASW 1825
S ++LIK G V+N D T +ADV IENG I + K + A+ IDATG VLPGG+D + + ++++SGTKAA+ GGTT V+ + K+ESL + YE + + C+ A+ + + +++ L++ K V ++ K + ++ D EL+ AL C+D + VHAEN ++VA I +E L G++GPEG +SRPE++E EAV R +TIA CPI+ V + S+ D + K ++ G + A V N +Y +W AA+FVT+P L+++ T LL + + +N V S H F K KA G++DF I G GVQ RM ++W++ V G+M+ FV S+ AK+ N+YP KG I G+DAD++VW +S + ++ GD+N++E++ CH P I G VV ++ G FT ++GSG+ L T Y K+++ + + K + R PY G V K++ M + GG + + + I R S + PPGG + W
Sbjct: 4 SSATVRILIKGGKVVNDDFTQEADVYIENGIIQQVGKELMIPGGAKVIDATGKLVLPGGIDTSVHLNESFMNGTTADDFYSGTKAALAGGTTMVIGHVLPEKNESLLDAYEKARSHADAKACCDYALHMGVTWWGPKARAQMETLVRDKGVNSF-QMYMAYKDMYMLR--DSELFQALQNCKDIGAVARVHAENGELVAESSLSHVFIFTHKGAREALDLGISGPEGIEISRPEELEAEAVHRAITIANRAHCPIYLVNVSSMSAGDVLA--SAKMQGKVVHGETTTAHAVLNGMQYYHQDWAHAAAFVTVPPLRLDPNTP---NYLLSLLGNDTLNVVTSDHRPFTTKQKAMGKDDFTKIPHGVPGVQDRMSVMWERGVVGGKMDENRFVAVTSSNAAKIYNLYPRKGRIIPGADADVVVWDPESTRTISVTTQWQGGDVNLYENLRCHGVPLVTISRGRVVYEN-GIFTCAEGSGKFY--PLRTFPDYLYKKMVQREKCQAL-KGVERTPYTGDVAAVQNSGKKDLGPADGDMNPRPCTRHGGVRDLHESSFSLSGAQIDDNVPKRASARILAPPGGRSSGIW 576
BLAST of Dihydropyrimidinase vs. Ensembl Xenopus
Match: dpysl4 (dihydropyrimidinase like 4 [Source:NCBI gene;Acc:548482]) HSP 1 Score: 300.056 bits (767), Expect = 5.161e-93 Identity = 188/572 (32.87%), Postives = 298/572 (52.10%), Query Frame = 2
Query: 158 KLLIKCGTVINHDCTYDADVLIENGKIVNIAKN-IEDSLAECIDATGCFVLPGGVDAETNFAAKRGGIVSPENYFSGTKAAIYGGTTTVVNCLEIMKDESLKEKYEMEKDIISKEIVCNLAIQLCLPEVNEAIKSEFNELLQSKSVVPLVRLSTVDKGCHCVKIDDEELYDALCWCRDNSVLPTVHAENDKMVAILEKELLADGVTGPEGHYLSRPEKVEDEAVFRVLTIAEMVKCPIHFGKVYAKSSLDKIMDWQRKSSNTIICGTSLVALVH-NAEKYRDPNWKVAASFVTMPALKMNKTTEFQCTELLETVASRKINHVASSHLVFDMKHKASGRNDFRCIIPGTNGVQYRMKILWDKAVKSGRMEPTSFVNCVSTTPAKLANIYPHKGTISIGSDADIIVW-----KGDSVSHSNFEAGDINVFEDVICHSGPKYVIVNGIVVLDHEGNFTASKGSGQIVSPSLETMNSYFQKQLINYKLSHEVEKKIAREPYDGPVIDPSADNKEEKHVLYSHM-------------VNNDVYKRGGPAEDKKEALPPGQRVIRTSVKTAQPPGGSA 1813
+LLIK G ++N D ++ AD+ IE+G I I +N I + IDA G V+PGG+D T G+ S +++F GTKAA+ GGTT +++ + +L + Y+ ++ ++ C+ ++ + + +E++K E L++ K V + C D E+Y+ RD + VHAEN ++ +K +L G+TGPEGH LS PE+VE EA +R +TIA+ CP++ KV ++ + D I +RK ++ G +L A + + Y NW AA++VT P + + +T T LL + ++ S+H F KA G+++F I GTNG++ RM I+WDK V SG+M+ +FV ST AKL N+YP KG I+ GSDAD+++W K S N ++N+FE + CH P+ VI G +VL+ +GN S+GSG+ V +T Y K++ E+ + + R YDGPV D + K S + +++ + G ED + +P RT+ K PPGG +
Sbjct: 7 RLLIKGGKIVNDDQSFLADIYIEDGLIKQIGENLIVPGGVKTIDAHGLLVIPGGIDVHTRLQMPVMGMTSADDFFQGTKAALAGGTTMIIDHVFPDSGMNLVQAYDQWREWADGKVCCDYSLHIDITYWHESLKEELEALVKDKGVNSFLVFMAYKDQYQCT---DAEMYEIFSIIRDLGAIAQVHAENGDIIQEEQKRMLECGITGPEGHVLSHPEEVEAEAAYRAITIAKQANCPLYITKVMSRGAADVIAQAKRK--GIVVYGETLTASIGTDGTHYWSKNWAKAAAYVTSPPISPDPSTPDHLTSLL---SCGDLHVTGSAHCTFTTAQKAVGKDNFILIPEGTNGIEERMTIIWDKCVTSGKMDENAFVAVTSTNAAKLFNLYPRKGRIATGSDADLVIWNPKTAKIISAKTHNMNV-ELNIFEGMECHGAPEVVISQGRIVLE-DGNLHVSQGSGRFV--PRKTFPDYVYKRIKARNRLAEI-RGVPRGLYDGPVHDVTITTKSAASTPASRIACPGKIQMGPVRNLHHSGFSLSGSQED--DHVPR-----RTTQKIVAPPGGRS 558
BLAST of Dihydropyrimidinase vs. Ensembl Xenopus
Match: dpysl4 (dihydropyrimidinase like 4 [Source:NCBI gene;Acc:548482]) HSP 1 Score: 300.442 bits (768), Expect = 5.388e-93 Identity = 188/572 (32.87%), Postives = 298/572 (52.10%), Query Frame = 2
Query: 158 KLLIKCGTVINHDCTYDADVLIENGKIVNIAKN-IEDSLAECIDATGCFVLPGGVDAETNFAAKRGGIVSPENYFSGTKAAIYGGTTTVVNCLEIMKDESLKEKYEMEKDIISKEIVCNLAIQLCLPEVNEAIKSEFNELLQSKSVVPLVRLSTVDKGCHCVKIDDEELYDALCWCRDNSVLPTVHAENDKMVAILEKELLADGVTGPEGHYLSRPEKVEDEAVFRVLTIAEMVKCPIHFGKVYAKSSLDKIMDWQRKSSNTIICGTSLVALVH-NAEKYRDPNWKVAASFVTMPALKMNKTTEFQCTELLETVASRKINHVASSHLVFDMKHKASGRNDFRCIIPGTNGVQYRMKILWDKAVKSGRMEPTSFVNCVSTTPAKLANIYPHKGTISIGSDADIIVW-----KGDSVSHSNFEAGDINVFEDVICHSGPKYVIVNGIVVLDHEGNFTASKGSGQIVSPSLETMNSYFQKQLINYKLSHEVEKKIAREPYDGPVIDPSADNKEEKHVLYSHM-------------VNNDVYKRGGPAEDKKEALPPGQRVIRTSVKTAQPPGGSA 1813
+LLIK G ++N D ++ AD+ IE+G I I +N I + IDA G V+PGG+D T G+ S +++F GTKAA+ GGTT +++ + +L + Y+ ++ ++ C+ ++ + + +E++K E L++ K V + C D E+Y+ RD + VHAEN ++ +K +L G+TGPEGH LS PE+VE EA +R +TIA+ CP++ KV ++ + D I +RK ++ G +L A + + Y NW AA++VT P + + +T T LL + ++ S+H F KA G+++F I GTNG++ RM I+WDK V SG+M+ +FV ST AKL N+YP KG I+ GSDAD+++W K S N ++N+FE + CH P+ VI G +VL+ +GN S+GSG+ V +T Y K++ E+ + + R YDGPV D + K S + +++ + G ED + +P RT+ K PPGG +
Sbjct: 13 RLLIKGGKIVNDDQSFLADIYIEDGLIKQIGENLIVPGGVKTIDAHGLLVIPGGIDVHTRLQMPVMGMTSADDFFQGTKAALAGGTTMIIDHVFPDSGMNLVQAYDQWREWADGKVCCDYSLHIDITYWHESLKEELEALVKDKGVNSFLVFMAYKDQYQCT---DAEMYEIFSIIRDLGAIAQVHAENGDIIQEEQKRMLECGITGPEGHVLSHPEEVEAEAAYRAITIAKQANCPLYITKVMSRGAADVIAQAKRK--GIVVYGETLTASIGTDGTHYWSKNWAKAAAYVTSPPISPDPSTPDHLTSLL---SCGDLHVTGSAHCTFTTAQKAVGKDNFILIPEGTNGIEERMTIIWDKCVTSGKMDENAFVAVTSTNAAKLFNLYPRKGRIATGSDADLVIWNPKTAKIISAKTHNMNV-ELNIFEGMECHGAPEVVISQGRIVLE-DGNLHVSQGSGRFV--PRKTFPDYVYKRIKARNRLAEI-RGVPRGLYDGPVHDVTITTKSAASTPASRIACPGKIQMGPVRNLHHSGFSLSGSQED--DHVPR-----RTTQKIVAPPGGRS 564
BLAST of Dihydropyrimidinase vs. Ensembl Xenopus
Match: dpysl4 (dihydropyrimidinase like 4 [Source:NCBI gene;Acc:548482]) HSP 1 Score: 300.827 bits (769), Expect = 5.719e-93 Identity = 189/575 (32.87%), Postives = 299/575 (52.00%), Query Frame = 2
Query: 149 TQKKLLIKCGTVINHDCTYDADVLIENGKIVNIAKN-IEDSLAECIDATGCFVLPGGVDAETNFAAKRGGIVSPENYFSGTKAAIYGGTTTVVNCLEIMKDESLKEKYEMEKDIISKEIVCNLAIQLCLPEVNEAIKSEFNELLQSKSVVPLVRLSTVDKGCHCVKIDDEELYDALCWCRDNSVLPTVHAENDKMVAILEKELLADGVTGPEGHYLSRPEKVEDEAVFRVLTIAEMVKCPIHFGKVYAKSSLDKIMDWQRKSSNTIICGTSLVALVH-NAEKYRDPNWKVAASFVTMPALKMNKTTEFQCTELLETVASRKINHVASSHLVFDMKHKASGRNDFRCIIPGTNGVQYRMKILWDKAVKSGRMEPTSFVNCVSTTPAKLANIYPHKGTISIGSDADIIVW-----KGDSVSHSNFEAGDINVFEDVICHSGPKYVIVNGIVVLDHEGNFTASKGSGQIVSPSLETMNSYFQKQLINYKLSHEVEKKIAREPYDGPVIDPSADNKEEKHVLYSHM-------------VNNDVYKRGGPAEDKKEALPPGQRVIRTSVKTAQPPGGSA 1813
T +LLIK G ++N D ++ AD+ IE+G I I +N I + IDA G V+PGG+D T G+ S +++F GTKAA+ GGTT +++ + +L + Y+ ++ ++ C+ ++ + + +E++K E L++ K V + C D E+Y+ RD + VHAEN ++ +K +L G+TGPEGH LS PE+VE EA +R +TIA+ CP++ KV ++ + D I +RK ++ G +L A + + Y NW AA++VT P + + +T T LL + ++ S+H F KA G+++F I GTNG++ RM I+WDK V SG+M+ +FV ST AKL N+YP KG I+ GSDAD+++W K S N ++N+FE + CH P+ VI G +VL+ +GN S+GSG+ V +T Y K++ E+ + + R YDGPV D + K S + +++ + G ED + +P RT+ K PPGG +
Sbjct: 30 TYDRLLIKGGKIVNDDQSFLADIYIEDGLIKQIGENLIVPGGVKTIDAHGLLVIPGGIDVHTRLQMPVMGMTSADDFFQGTKAALAGGTTMIIDHVFPDSGMNLVQAYDQWREWADGKVCCDYSLHIDITYWHESLKEELEALVKDKGVNSFLVFMAYKDQYQCT---DAEMYEIFSIIRDLGAIAQVHAENGDIIQEEQKRMLECGITGPEGHVLSHPEEVEAEAAYRAITIAKQANCPLYITKVMSRGAADVIAQAKRK--GIVVYGETLTASIGTDGTHYWSKNWAKAAAYVTSPPISPDPSTPDHLTSLL---SCGDLHVTGSAHCTFTTAQKAVGKDNFILIPEGTNGIEERMTIIWDKCVTSGKMDENAFVAVTSTNAAKLFNLYPRKGRIATGSDADLVIWNPKTAKIISAKTHNMNV-ELNIFEGMECHGAPEVVISQGRIVLE-DGNLHVSQGSGRFV--PRKTFPDYVYKRIKARNRLAEI-RGVPRGLYDGPVHDVTITTKSAASTPASRIACPGKIQMGPVRNLHHSGFSLSGSQED--DHVPR-----RTTQKIVAPPGGRS 584
BLAST of Dihydropyrimidinase vs. Ensembl Xenopus
Match: dpysl4 (dihydropyrimidinase like 4 [Source:NCBI gene;Acc:548482]) HSP 1 Score: 296.975 bits (759), Expect = 1.141e-91 Identity = 188/572 (32.87%), Postives = 298/572 (52.10%), Query Frame = 2
Query: 158 KLLIKCGTVINHDCTYDADVLIENGKIVNIAKN-IEDSLAECIDATGCFVLPGGVDAETNFAAKRGGIVSPENYFSGTKAAIYGGTTTVVNCLEIMKDESLKEKYEMEKDIISKEIVCNLAIQLCLPEVNEAIKSEFNELLQSKSVVPLVRLSTVDKGCHCVKIDDEELYDALCWCRDNSVLPTVHAENDKMVAILEKELLADGVTGPEGHYLSRPEKVEDEAVFRVLTIAEMVKCPIHFGKVYAKSSLDKIMDWQRKSSNTIICGTSLVALVH-NAEKYRDPNWKVAASFVTMPALKMNKTTEFQCTELLETVASRKINHVASSHLVFDMKHKASGRNDFRCIIPGTNGVQYRMKILWDKAVKSGRMEPTSFVNCVSTTPAKLANIYPHKGTISIGSDADIIVW-----KGDSVSHSNFEAGDINVFEDVICHSGPKYVIVNGIVVLDHEGNFTASKGSGQIVSPSLETMNSYFQKQLINYKLSHEVEKKIAREPYDGPVIDPSADNKEEKHVLYSHM-------------VNNDVYKRGGPAEDKKEALPPGQRVIRTSVKTAQPPGGSA 1813
+LLIK G ++N D ++ AD+ IE+G I I +N I + IDA G V+PGG+D T G+ S +++F GTKAA+ GGTT +++ + +L + Y+ ++ ++ C+ ++ + + +E++K E L++ K V + C D E+Y+ RD + VHAEN ++ +K +L G+TGPEGH LS PE+VE EA +R +TIA+ CP++ KV ++ + D I +RK ++ G +L A + + Y NW AA++VT P + + +T T LL + ++ S+H F KA G+++F I GTNG++ RM I+WDK V SG+M+ +FV ST AKL N+YP KG I+ GSDAD+++W K S N ++N+FE + CH P+ VI G +VL+ +GN S+GSG+ V +T Y K++ E+ + + R YDGPV D + K S + +++ + G ED + +P RT+ K PPGG +
Sbjct: 14 RLLIKGGKIVNDDQSFLADIYIEDGLIKQIGENLIVPGGVKTIDAHGLLVIPGGIDVHTRLQMPVMGMTSADDFFQGTKAALAGGTTMIIDHVFPDSGMNLVQAYDQWREWADGKVCCDYSLHIDITYWHESLKEELEALVKDKGVNSFLVFMAYKDQYQCT---DAEMYEIFSIIRDLGAIAQVHAENGDIIQ-EQKRMLECGITGPEGHVLSHPEEVEAEAAYRAITIAKQANCPLYITKVMSRGAADVIAQAKRK--GIVVYGETLTASIGTDGTHYWSKNWAKAAAYVTSPPISPDPSTPDHLTSLL---SCGDLHVTGSAHCTFTTAQKAVGKDNFILIPEGTNGIEERMTIIWDKCVTSGKMDENAFVAVTSTNAAKLFNLYPRKGRIATGSDADLVIWNPKTAKIISAKTHNMNV-ELNIFEGMECHGAPEVVISQGRIVLE-DGNLHVSQGSGRFV--PRKTFPDYVYKRIKARNRLAEI-RGVPRGLYDGPVHDVTITTKSAASTPASRIACPGKIQMGPVRNLHHSGFSLSGSQED--DHVPR-----RTTQKIVAPPGGRS 564
BLAST of Dihydropyrimidinase vs. Ensembl Xenopus
Match: rfc1 (replication factor C subunit 1 [Source:Xenbase;Acc:XB-GENE-964734]) HSP 1 Score: 296.975 bits (759), Expect = 1.241e-91 Identity = 177/519 (34.10%), Postives = 283/519 (54.53%), Query Frame = 2
Query: 128 KVLFMSETQK------KLLIKCGTVINHDCTYDADVLIENGKIVNIAKN-IEDSLAECIDATGCFVLPGGVDAETNFAAKRGGIVSPENYFSGTKAAIYGGTTTVVNCLEIMKDESLKEKYEMEKDIISKEIVCNLAIQLCLPEVNEAIKSEFNELLQSKSVVP-LVRLSTVDKGCHCVKIDDEELYDALCWCRDNSVLPTVHAENDKMVAILEKELLADGVTGPEGHYLSRPEKVEDEAVFRVLTIAEMVKCPIHFGKVYAKSSLDKIMDWQRKSSNTIICGTSLVA-LVHNAEKYRDPNWKVAASFVTMPALKMNKTTEFQCTELLETVASRKINHVASSHLVFDMKHKASGRNDFRCIIPGTNGVQYRMKILWDKAVKSGRMEPTSFVNCVSTTPAKLANIYPHKGTISIGSDADIIVWKGDSV----SHSNFEAGDINVFEDVICHSGPKYVIVNGIVVLDHEGNFTASKGSGQIVSPSLETMNSYFQKQLINYKLSHEVEKKIAREPYDGPVID 1645
+V F SE K +LLIK G ++N D ++ AD+ +E+G I I N I + I+A G V+PGG+D T+ G+ + +++F GTKAA+ GGTT +V+ + + SL E +E ++ + C+ ++ + + N+++K E L++ K V +V ++ D ++ + ELY+ + + VHAEN ++A + +L G+TGPEGH LSRPE++E EAVFR +TIA CP++ KV +KSS+D I Q + ++ G + A L + Y NW AA+FVT P L + TT LL AS + S+H F KA G+++F I GTNG++ RM ++WDKAV +G+M+ FV ST AK+ N+YP KG I++GSD+D+++W D+V + S+ A + N+FE + P VI G ++++ +G ++G+G+ + S Y K++ E+ + R YDGPV D
Sbjct: 1 QVYFESEGNKHLPSSDRLLIKGGRIVNDDQSFYADIYMEDGLIKQIGDNLIVPGGVKTIEANGKMVIPGGIDVHTHLQMPYRGMTTVDDFFQGTKAALAGGTTMIVDHVIPEPEASLTEAFEKWREWADGKTCCDYSLHVDITHWNDSVKQEVEALVKQKGVNSFMVYMAYKD----LYQMSNTELYEVFTFLGGLGAIAQVHAENGDIIAQEQNRMLELGITGPEGHVLSRPEELEAEAVFRAITIASQTNCPLYVTKVMSKSSVDLIS--QARKKGYVVFGEPITASLGTDGTHYWSKNWAKAAAFVTSPPLSPDPTTPDYINSLL---ASGDLQVTGSAHATFSTAQKAIGKDNFTLIPEGTNGIEERMSVIWDKAVATGKMDENQFVAVTSTNAAKIFNLYPRKGRIAVGSDSDLVIWDPDAVKIVSAKSHHSAAEYNIFEGMELRGAPLVVICQGKIMME-DGTLHVTQGTGRFIPCS--PFPDYVYKRIKARTKMAELH-AVPRGMYDGPVYD 506
BLAST of Dihydropyrimidinase vs. Ensembl Mouse
Match: Dpysl3 (dihydropyrimidinase-like 3 [Source:MGI Symbol;Acc:MGI:1349762]) HSP 1 Score: 298.13 bits (762), Expect = 3.005e-92 Identity = 174/505 (34.46%), Postives = 279/505 (55.25%), Query Frame = 2
Query: 149 TQKKLLIKCGTVINHDCTYDADVLIENGKIVNIAKN-IEDSLAECIDATGCFVLPGGVDAETNFAAKRGGIVSPENYFSGTKAAIYGGTTTVVNCLEIMKDESLKEKYEMEKDIISKEIVCNLAIQLCLPEVNEAIKSEFNELLQSKSVVP-LVRLSTVDKGCHCVKIDDEELYDALCWCRDNSVLPTVHAENDKMVAILEKELLADGVTGPEGHYLSRPEKVEDEAVFRVLTIAEMVKCPIHFGKVYAKSSLDKIMDWQRKSSNTIICGTSLVALVHNAEKYRDPNWKVAASFVTMPALKMNKTTEFQCTELLETVASRKINHVASSHLVFDMKHKASGRNDFRCIIPGTNGVQYRMKILWDKAVKSGRMEPTSFVNCVSTTPAKLANIYPHKGTISIGSDADIIVWKGDS---VSHSNFEA-GDINVFEDVICHSGPKYVIVNGIVVLDHEGNFTASKGSGQIVSPSLETMNSYFQKQLINYKLSHEVEKKIAREPYDGPVID 1645
T +LLIK G ++N D ++ AD+ +E+G I I N I + I+A G V+PGG+D T+F G+ + +++F GTKAA+ GGTT +++ + + SL E YE ++ + C+ A+ + + N+++K E L + K V +V ++ D ++ + ELY+ + + VHAEN ++A + +L G+TGPEGH LSRPE++E EAVFR +T+A CP++ KV +KS+ D ++ RK N + +L + Y NW AA+FVT P L + TT LL AS + S+H F KA G+++F I GTNGV+ RM ++WDKAV +G+M+ FV ST AK+ N+YP KG I++GSD+D+++W D+ VS N ++ + N+FE + P VI G ++L+ +GN ++G+G+ + S + Y K++ + ++ + R YDGPV D
Sbjct: 13 TSDRLLIKGGRIVNDDQSFYADIYMEDGLIKQIGDNLIVPGGVKTIEANGKMVIPGGIDVHTHFQMPYKGMTTVDDFFQGTKAALAGGTTMIIDHVVPEPESSLTEAYEKWREWADGKSCCDYALHVDITHWNDSVKQEVQSLSKEKGVNSFMVYMAYKD----LYQVSNTELYEIFTCLGELGAIAQVHAENGDIIAQEQARMLEMGITGPEGHVLSRPEELEAEAVFRAITVASQTNCPLYVTKVMSKSAAD-LISQARKKGNVVFGEPITASLGIDGTHYWSKNWAKAAAFVTSPPLSPDPTTPDYINSLL---ASGDLQLSGSAHCTFSTAQKAIGKDNFTAIPEGTNGVEERMSVIWDKAVATGKMDENQFVAVTSTNAAKIFNLYPRKGRIAVGSDSDLVIWDPDALKIVSAKNHQSVAEYNIFEGMELRGAPLVVICQGKIMLE-DGNLHVTQGAGRFIPCS--PFSDYVYKRIKARRKMADLH-AVPRGMYDGPVFD 505
BLAST of Dihydropyrimidinase vs. Ensembl Mouse
Match: Dpysl3 (dihydropyrimidinase-like 3 [Source:MGI Symbol;Acc:MGI:1349762]) HSP 1 Score: 296.975 bits (759), Expect = 8.196e-92 Identity = 173/502 (34.46%), Postives = 278/502 (55.38%), Query Frame = 2
Query: 158 KLLIKCGTVINHDCTYDADVLIENGKIVNIAKN-IEDSLAECIDATGCFVLPGGVDAETNFAAKRGGIVSPENYFSGTKAAIYGGTTTVVNCLEIMKDESLKEKYEMEKDIISKEIVCNLAIQLCLPEVNEAIKSEFNELLQSKSVVP-LVRLSTVDKGCHCVKIDDEELYDALCWCRDNSVLPTVHAENDKMVAILEKELLADGVTGPEGHYLSRPEKVEDEAVFRVLTIAEMVKCPIHFGKVYAKSSLDKIMDWQRKSSNTIICGTSLVALVHNAEKYRDPNWKVAASFVTMPALKMNKTTEFQCTELLETVASRKINHVASSHLVFDMKHKASGRNDFRCIIPGTNGVQYRMKILWDKAVKSGRMEPTSFVNCVSTTPAKLANIYPHKGTISIGSDADIIVWKGDS---VSHSNFEA-GDINVFEDVICHSGPKYVIVNGIVVLDHEGNFTASKGSGQIVSPSLETMNSYFQKQLINYKLSHEVEKKIAREPYDGPVID 1645
+LLIK G ++N D ++ AD+ +E+G I I N I + I+A G V+PGG+D T+F G+ + +++F GTKAA+ GGTT +++ + + SL E YE ++ + C+ A+ + + N+++K E L + K V +V ++ D ++ + ELY+ + + VHAEN ++A + +L G+TGPEGH LSRPE++E EAVFR +T+A CP++ KV +KS+ D ++ RK N + +L + Y NW AA+FVT P L + TT LL AS + S+H F KA G+++F I GTNGV+ RM ++WDKAV +G+M+ FV ST AK+ N+YP KG I++GSD+D+++W D+ VS N ++ + N+FE + P VI G ++L+ +GN ++G+G+ + S + Y K++ + ++ + R YDGPV D
Sbjct: 14 RLLIKGGRIVNDDQSFYADIYMEDGLIKQIGDNLIVPGGVKTIEANGKMVIPGGIDVHTHFQMPYKGMTTVDDFFQGTKAALAGGTTMIIDHVVPEPESSLTEAYEKWREWADGKSCCDYALHVDITHWNDSVKQEVQSLSKEKGVNSFMVYMAYKD----LYQVSNTELYEIFTCLGELGAIAQVHAENGDIIAQEQARMLEMGITGPEGHVLSRPEELEAEAVFRAITVASQTNCPLYVTKVMSKSAAD-LISQARKKGNVVFGEPITASLGIDGTHYWSKNWAKAAAFVTSPPLSPDPTTPDYINSLL---ASGDLQLSGSAHCTFSTAQKAIGKDNFTAIPEGTNGVEERMSVIWDKAVATGKMDENQFVAVTSTNAAKIFNLYPRKGRIAVGSDSDLVIWDPDALKIVSAKNHQSVAEYNIFEGMELRGAPLVVICQGKIMLE-DGNLHVTQGAGRFIPCS--PFSDYVYKRIKARRKMADLH-AVPRGMYDGPVFD 503
BLAST of Dihydropyrimidinase vs. Ensembl Mouse
Match: Crmp1 (collapsin response mediator protein 1 [Source:MGI Symbol;Acc:MGI:107793]) HSP 1 Score: 295.434 bits (755), Expect = 3.230e-91 Identity = 190/584 (32.53%), Postives = 295/584 (50.51%), Query Frame = 2
Query: 149 TQKKLLIKCGTVINHDCTYDADVLIENGKIVNIAKN-IEDSLAECIDATGCFVLPGGVDAETNFAAKRGGIVSPENYFSGTKAAIYGGTTTVVNCLEIMKDESLKEKYEMEKDIISKEIVCNLAIQLCLPEVNEAIKSEFNELLQSKSVVPL-VRLSTVDKGCHCVKIDDEELYDALCWCRDNSVLPTVHAENDKMVAILEKELLADGVTGPEGHYLSRPEKVEDEAVFRVLTIAEMVKCPIHFGKVYAKSSLDKIMDWQRKSSNTIICGTSLVALVHNAEKYRDPNWKVAASFVTMPALKMNKTTEFQCTELLETVASRKINHVASSHLVFDMKHKASGRNDFRCIIPGTNGVQYRMKILWDKAVKSGRMEPTSFVNCVSTTPAKLANIYPHKGTISIGSDADIIVWKGDSV----SHSNFEAGDINVFEDVICHSGPKYVIVNGIVVLDHEGNFTASKGSGQIVSPSLETMNSYFQKQLINYKLS--HEVEKKIAREPYDGPVID-----------PSADNKEEKH----VLYSHMVNNDVYKRGGPAEDKKEALPPGQRVIRTSVKTAQPPGGSAQASWWG 1831
T +LLI+ G +IN D ++ ADV +E+G I I +N I + I+A G V+PGG+D T G+ S +++F GTKAA+ GGTT +++ + SL +E + + C+ ++ + + + ++ E L+Q K V V ++ D ++ D +LY+A + + + VHAEN ++A +K +L G+TGPEGH LSRPE++E EAVFR + IA + CP++ KV +KS+ D I+ RK + +L + Y NW AA+FVT P L + TT T LL A + S H + KA G+++F I G NG++ RM ++WDKAV +G+M+ FV ST AK+ N+YP KG I++GSDAD+++W D + + S+ + N+FE + CH P VI G +V + +GN + SKG G+ + P +Q+ I K+ H V + + YDGPV + PSA + KH + H N + G D G R++ PPGG + + G
Sbjct: 13 TSDRLLIRGGRIINDDQSFYADVYLEDGLIKQIGENLIVPGGVKTIEANGRMVIPGGIDVNTYLQKPSQGMTSADDFFQGTKAALAGGTTMIIDHVVPEPGSSLLTSFEKWHEAADTKSCCDYSLHVDITSWYDGVREELEVLVQDKGVNSFQVYMAYKD----LYQMSDSQLYEAFTFLKGLGAVILVHAENGDLIAQEQKRILEMGITGPEGHALSRPEELEAEAVFRAIAIAGRINCPVYITKVMSKSAAD-IIALARKKGPLVFGEPIAASLGTDGTHYWSKNWAKAAAFVTSPPLSPDPTTPDYLTSLL---ACGDLQVTGSGHCPYSTAQKAVGKDNFTLIPEGVNGIEERMTVVWDKAVATGKMDENQFVAVTSTNAAKIFNLYPRKGRIAVGSDADVVIWDPDKMKTITAKSHKSTVEYNIFEGMECHGSPLVVISQGKIVFE-DGNISVSKGMGRFI-PRKPFPEHLYQRVRIRSKVFGLHSVSRGM----YDGPVYEVPATPKHAAPAPSAKSSPSKHQPPPIRNLHQSN---FSLSGAQIDDNNPRRTGHRIV-------APPGGRSNITSLG 572
BLAST of Dihydropyrimidinase vs. Ensembl Mouse
Match: Dpysl3 (dihydropyrimidinase-like 3 [Source:MGI Symbol;Acc:MGI:1349762]) HSP 1 Score: 297.745 bits (761), Expect = 6.030e-91 Identity = 175/516 (33.91%), Postives = 284/516 (55.04%), Query Frame = 2
Query: 116 KLLIKVLFMSETQKKLLIKCGTVINHDCTYDADVLIENGKIVNIAKN-IEDSLAECIDATGCFVLPGGVDAETNFAAKRGGIVSPENYFSGTKAAIYGGTTTVVNCLEIMKDESLKEKYEMEKDIISKEIVCNLAIQLCLPEVNEAIKSEFNELLQSKSVVP-LVRLSTVDKGCHCVKIDDEELYDALCWCRDNSVLPTVHAENDKMVAILEKELLADGVTGPEGHYLSRPEKVEDEAVFRVLTIAEMVKCPIHFGKVYAKSSLDKIMDWQRKSSNTIICGTSLVALVHNAEKYRDPNWKVAASFVTMPALKMNKTTEFQCTELLETVASRKINHVASSHLVFDMKHKASGRNDFRCIIPGTNGVQYRMKILWDKAVKSGRMEPTSFVNCVSTTPAKLANIYPHKGTISIGSDADIIVWKGDS---VSHSNFEA-GDINVFEDVICHSGPKYVIVNGIVVLDHEGNFTASKGSGQIVSPSLETMNSYFQKQLINYKLSHEVEKKIAREPYDGPVID 1645
K +++ L + +LLIK G ++N D ++ AD+ +E+G I I N I + I+A G V+PGG+D T+F G+ + +++F GTKAA+ GGTT +++ + + SL E YE ++ + C+ A+ + + N+++K E L + K V +V ++ D ++ + ELY+ + + VHAEN ++A + +L G+TGPEGH LSRPE++E EAVFR +T+A CP++ KV +KS+ D ++ RK N + +L + Y NW AA+FVT P L + TT LL AS + S+H F KA G+++F I GTNGV+ RM ++WDKAV +G+M+ FV ST AK+ N+YP KG I++GSD+D+++W D+ VS N ++ + N+FE + P VI G ++L+ +GN ++G+G+ + S + Y K++ + ++ + R YDGPV D
Sbjct: 115 KEVLQNLGPKDKSDRLLIKGGRIVNDDQSFYADIYMEDGLIKQIGDNLIVPGGVKTIEANGKMVIPGGIDVHTHFQMPYKGMTTVDDFFQGTKAALAGGTTMIIDHVVPEPESSLTEAYEKWREWADGKSCCDYALHVDITHWNDSVKQEVQSLSKEKGVNSFMVYMAYKD----LYQVSNTELYEIFTCLGELGAIAQVHAENGDIIAQEQARMLEMGITGPEGHVLSRPEELEAEAVFRAITVASQTNCPLYVTKVMSKSAAD-LISQARKKGNVVFGEPITASLGIDGTHYWSKNWAKAAAFVTSPPLSPDPTTPDYINSLL---ASGDLQLSGSAHCTFSTAQKAIGKDNFTAIPEGTNGVEERMSVIWDKAVATGKMDENQFVAVTSTNAAKIFNLYPRKGRIAVGSDSDLVIWDPDALKIVSAKNHQSVAEYNIFEGMELRGAPLVVICQGKIMLE-DGNLHVTQGAGRFIPCS--PFSDYVYKRIKARRKMADLH-AVPRGMYDGPVFD 618
BLAST of Dihydropyrimidinase vs. Ensembl Mouse
Match: Dpysl5 (dihydropyrimidinase-like 5 [Source:MGI Symbol;Acc:MGI:1929772]) HSP 1 Score: 291.967 bits (746), Expect = 4.819e-90 Identity = 183/575 (31.83%), Postives = 293/575 (50.96%), Query Frame = 2
Query: 134 LFMSETQKKLLIKCGTVINHDCTYDADVLIENGKIVNIAKNIE-DSLAECIDATGCFVLPGGVDAETNFAAKRGGIVSPENYFSGTKAAIYGGTTTVVNCLEIMKDESLKEKYEMEKDIISKEIVCNLAIQLCLPEVNEAIKSEFNELLQSKSVVPLVRLSTVDKGCHCVKIDDEELYDALCWCRDNSVLPTVHAENDKMVAILEKELLADGVTGPEGHYLSRPEKVEDEAVFRVLTIAEMVKCPIHFGKVYAKSSLDKIMDWQRKSSNTIICGTSLVALVHNAEKYRDPNWKVAASFVTMPALKMNKTTEFQCTELLETVASRKINHVASSHLVFDMKHKASGRNDFRCIIPGTNGVQYRMKILWDKAVKSGRMEPTSFVNCVSTTPAKLANIYPHKGTISIGSDADIIVWKGDSV----SHSNFEAGDINVFEDVICHSGPKYVIVNGIVVLDHEGNFTASKGSGQIVSPSLETMNSYFQKQLINYKLSHEVEKKIAREPYDGPVIDPSADNKEEKHVLYSHMVNNDVYKRGGPAEDKKEALPPGQRVI------RTSVKTAQPPGGSAQASW 1825
+ + ++LIK G V+N DCT++ADV IE+G I + + + A+ IDATG V+PGG+D T+F ++++ GTKAA+ GGTT ++ + K+ SL E YE + + ++ C+ A+ + + +K+E L++ K V T + D ELY CRD +P VHAEN ++VA KE L G+TGPEG +S PE++E EA RV+TIA CPI+ V + S+ D ++ + ++ T+ Y +W AA++VT+P L+++ T T L+ +A+ +N VAS H F K KA G+ DF I G +GVQ RM ++W++ V G+M+ FV S+ AK+ N+YP KG I G+DAD++VW ++ + + + GD N++E++ CH P I G VV ++ G F ++G+G+ L + K+L+ + + +V + + R PY G V K+E + V + GG + + + I R S + PPGG + W
Sbjct: 1 MLANSASVRILIKGGKVVNDDCTHEADVYIESGIIQQVGRELMIPGGAKVIDATGKLVIPGGIDTSTHFHQTFMNATCVDDFYHGTKAALVGGTTMIIGHVLPDKETSLVEAYEKCRALADPKVCCDYALHVGITWWAPKVKAEMETLVREKGVNSFQMFMTYKD---LYMLRDSELYQVFHACRDIGAIPRVHAENGELVAEGAKEALDLGITGPEGIEISHPEELEAEATHRVITIANRTHCPIYLVNVSSISAGD-VIAAAKMQGKVVLAETTNAHATLTGLHYYHQDWSHAAAYVTVPPLRLDTNTS---TYLMSLLANDTLNIVASDHRPFTTKQKAMGKEDFTKIPHGVSGVQDRMSVVWERGVVGGKMDENRFVAVTSSNAAKILNLYPRKGRIIPGADADVVVWDPEATKTISASTQVQGGDFNLYENMRCHGVPLVTISRGRVVYEN-GVFMCAEGTGKFC--PLRSFPDIVYKKLVQREKTLKV-RGVDRTPYLGDVAIVVHPGKKEMGTPLADTPTRPVTRHGGMRDLHESSFSLSGSQIDDHVPKRASARILAPPGGRSSGIW 564
BLAST of Dihydropyrimidinase vs. UniProt/SwissProt
Match: sp|Q14195|DPYL3_HUMAN (Dihydropyrimidinase-related protein 3 OS=Homo sapiens OX=9606 GN=DPYSL3 PE=1 SV=1) HSP 1 Score: 302.753 bits (774), Expect = 3.751e-93 Identity = 175/505 (34.65%), Postives = 280/505 (55.45%), Query Frame = 2
Query: 149 TQKKLLIKCGTVINHDCTYDADVLIENGKIVNIAKN-IEDSLAECIDATGCFVLPGGVDAETNFAAKRGGIVSPENYFSGTKAAIYGGTTTVVNCLEIMKDESLKEKYEMEKDIISKEIVCNLAIQLCLPEVNEAIKSEFNELLQSKSVVP-LVRLSTVDKGCHCVKIDDEELYDALCWCRDNSVLPTVHAENDKMVAILEKELLADGVTGPEGHYLSRPEKVEDEAVFRVLTIAEMVKCPIHFGKVYAKSSLDKIMDWQRKSSNTIICGTSLVALVHNAEKYRDPNWKVAASFVTMPALKMNKTTEFQCTELLETVASRKINHVASSHLVFDMKHKASGRNDFRCIIPGTNGVQYRMKILWDKAVKSGRMEPTSFVNCVSTTPAKLANIYPHKGTISIGSDADIIVWKGDSV----SHSNFEAGDINVFEDVICHSGPKYVIVNGIVVLDHEGNFTASKGSGQIVSPSLETMNSYFQKQLINYKLSHEVEKKIAREPYDGPVID 1645
T +LLIK G ++N D ++ AD+ +E+G I I N I + I+A G V+PGG+D T+F G+ + +++F GTKAA+ GGTT +++ + + SL E YE ++ + C+ A+ + + N+++K E L++ K V +V ++ D ++ + ELY+ + + VHAEN ++A + +L G+TGPEGH LSRPE++E EAVFR +TIA CP++ KV +KS+ D ++ RK N + +L + Y NW AA+FVT P L + TT LL AS + S+H F KA G+++F I GTNGV+ RM ++WDKAV +G+M+ FV ST AK+ N+YP KG IS+GSD+D+++W D+V + ++ A + N+FE + P VI G ++L+ +GN ++G+G+ + S + Y K++ + ++ + R YDGPV D
Sbjct: 13 TSDRLLIKGGRIVNDDQSFYADIYMEDGLIKQIGDNLIVPGGVKTIEANGKMVIPGGIDVHTHFQMPYKGMTTVDDFFQGTKAALAGGTTMIIDHVVPEPESSLTEAYEKWREWADGKSCCDYALHVDITHWNDSVKQEVQNLIKDKGVNSFMVYMAYKD----LYQVSNTELYEIFTCLGELGAIAQVHAENGDIIAQEQTRMLEMGITGPEGHVLSRPEELEAEAVFRAITIASQTNCPLYVTKVMSKSAAD-LISQARKKGNVVFGEPITASLGIDGTHYWSKNWAKAAAFVTSPPLSPDPTTPDYINSLL---ASGDLQLSGSAHCTFSTAQKAIGKDNFTAIPEGTNGVEERMSVIWDKAVATGKMDENQFVAVTSTNAAKIFNLYPRKGRISVGSDSDLVIWDPDAVKIVSAKNHQSAAEYNIFEGMELRGAPLVVICQGKIMLE-DGNLHVTQGAGRFIPCS--PFSDYVYKRIKARRKMADLH-AVPRGMYDGPVFD 505
BLAST of Dihydropyrimidinase vs. UniProt/SwissProt
Match: sp|Q52PJ5|DPYL3_DANRE (Dihydropyrimidinase-related protein 3 OS=Danio rerio OX=7955 GN=dpysl3 PE=2 SV=1) HSP 1 Score: 298.516 bits (763), Expect = 1.460e-91 Identity = 187/572 (32.69%), Postives = 301/572 (52.62%), Query Frame = 2
Query: 149 TQKKLLIKCGTVINHDCTYDADVLIENGKIVNIAKN-IEDSLAECIDATGCFVLPGGVDAETNFAAKRGGIVSPENYFSGTKAAIYGGTTTVVNCLEIMKDESLKEKYEMEKDIISKEIVCNLAIQLCLPEVNEAIKSEFNELLQSKSVVPL-VRLSTVDKGCHCVKIDDEELYDALCWCRDNSVLPTVHAENDKMVAILEKELLADGVTGPEGHYLSRPEKVEDEAVFRVLTIAEMVKCPIHFGKVYAKSSLDKIMDWQRKSSNTIICGTSLVALVHNAEKYRDPNWKVAASFVTMPALKMNKTTEFQCTELLETVASRKINHVASSHLVFDMKHKASGRNDFRCIIPGTNGVQYRMKILWDKAVKSGRMEPTSFVNCVSTTPAKLANIYPHKGTISIGSDADIIVWKGDSV----SHSNFEAGDINVFEDVICHSGPKYVIVNGIVVLDHEGNFTASKGSGQIV--SPSLETMNSYFQKQLINYKLSHEVEKKIAREPYDGPVID---------PSADNKEEKHVLYSHMVNNDVYKRGGPAEDKKEALPPGQRVIRTSVKTAQPPGGSA 1813
T ++LLIK G ++N D ++ AD+ +E+G I I N I + I+A G V+PGG+D T+ G + +++ GTKAA+ GGTT +V+ + SL E ++ ++ C+ ++ + + N+++K E L++ K V V ++ D ++ + ELY+ + ++ + VHAEN +++A + +L G+TGPEGH LSRPE++E EAVFR +TIA CP++ +V +KS+ D I+ RK N + +L + Y NW AASFVT P L + TT LL AS ++ V S+H F + KA G++DF I G NG + RM I+WDKAV +G+M+ FV ST AK+ N+YP KG I++GSD+D+++W D+V + ++ A + NVFE + P V+ G +VL+ +GN A+ G+G+ + SP + F + + + + K + R YDGPV + PSA + + ++ + GP E P G+R++ PPGG +
Sbjct: 13 TSERLLIKGGRIVNDDQSFYADIYMEDGVIKQIGDNLIVPGGVKTIEANGKMVIPGGIDIHTHLQMPFRGTTTADDFTQGTKAALAGGTTMIVDHVIPEPGCSLLEAFDRWSKWADEKACCDYSLHVDITHWNDSVKQEVETLIKEKGVNSFQVYMAFKD----LYQMSNTELYEVFTFLGEHGGIAQVHAENGEIIAEEQARMLEMGITGPEGHVLSRPEELEAEAVFRAVTIASQTNCPLYVTRVMSKSAAD-IISQARKKGNVVFGEPITASLGTDGTHYWSKNWAKAASFVTSPPLSPDPTTPDYLNTLL---ASGDLSVVGSAHCTFSVAQKAIGKDDFTQIPEGVNGAEERMSIIWDKAVVTGKMDENMFVAVTSTNAAKILNLYPRKGRIAVGSDSDLVIWDTDAVRTITAKTHHSAAEYNVFEGMELRGAPMLVVCQGKIVLE-DGNLHATSGTGRFIPCSPFPD-----FAYKRVKARKQLAILKAVPRGMYDGPVSEFSPMSRGGTPSASTRTSPTKVPVRNLHQSGFTLSGPEE--APIRPAGRRIV-------VPPGGRS 561
BLAST of Dihydropyrimidinase vs. UniProt/SwissProt
Match: sp|Q62952|DPYL3_RAT (Dihydropyrimidinase-related protein 3 OS=Rattus norvegicus OX=10116 GN=Dpysl3 PE=1 SV=2) HSP 1 Score: 298.13 bits (762), Expect = 1.852e-91 Identity = 174/505 (34.46%), Postives = 279/505 (55.25%), Query Frame = 2
Query: 149 TQKKLLIKCGTVINHDCTYDADVLIENGKIVNIAKN-IEDSLAECIDATGCFVLPGGVDAETNFAAKRGGIVSPENYFSGTKAAIYGGTTTVVNCLEIMKDESLKEKYEMEKDIISKEIVCNLAIQLCLPEVNEAIKSEFNELLQSKSVVP-LVRLSTVDKGCHCVKIDDEELYDALCWCRDNSVLPTVHAENDKMVAILEKELLADGVTGPEGHYLSRPEKVEDEAVFRVLTIAEMVKCPIHFGKVYAKSSLDKIMDWQRKSSNTIICGTSLVALVHNAEKYRDPNWKVAASFVTMPALKMNKTTEFQCTELLETVASRKINHVASSHLVFDMKHKASGRNDFRCIIPGTNGVQYRMKILWDKAVKSGRMEPTSFVNCVSTTPAKLANIYPHKGTISIGSDADIIVWKGDS---VSHSNFEA-GDINVFEDVICHSGPKYVIVNGIVVLDHEGNFTASKGSGQIVSPSLETMNSYFQKQLINYKLSHEVEKKIAREPYDGPVID 1645
T +LLIK G ++N D ++ AD+ +E+G I I N I + I+A G V+PGG+D T+F G+ + +++F GTKAA+ GGTT +++ + + SL E YE ++ + C+ A+ + + N+++K E L + K V +V ++ D ++ + ELY+ + + VHAEN ++A + +L G+TGPEGH LSRPE++E EAVFR +T+A CP++ KV +KS+ D ++ RK N + +L + Y NW AA+FVT P L + TT LL AS + S+H F KA G+++F I GTNGV+ RM ++WDKAV +G+M+ FV ST AK+ N+YP KG I++GSD+D+++W D+ VS N ++ + N+FE + P VI G ++L+ +GN ++G+G+ + S + Y K++ + ++ + R YDGPV D
Sbjct: 13 TSDRLLIKGGRIVNDDQSFYADIYMEDGLIKQIGDNLIVPGGVKTIEANGKMVMPGGIDVHTHFQMPYKGMTTVDDFFQGTKAALAGGTTMIIDHVVPEPESSLTEAYEKWREWADGKSCCDYALHVDITHWNDSVKQEVQNLSKEKGVNSFMVYMAYKD----LYQVSNTELYEIFTCLGELGAIAQVHAENGDIIAQEQARMLEMGITGPEGHVLSRPEELEAEAVFRAITVASQTNCPLYVTKVMSKSAAD-LISQARKKGNVVFGEPITASLGIDGTHYWSKNWAKAAAFVTSPPLSPDPTTPDYINSLL---ASGDLQLSGSAHCTFSTAQKAIGKDNFTAIPEGTNGVEERMSVIWDKAVATGKMDENQFVAVTSTNAAKIFNLYPRKGRIAVGSDSDLVIWDPDAVKIVSAKNHQSVAEYNIFEGMELRGAPLVVICQGKIMLE-DGNLHVTQGAGRFIPCS--PFSDYVYKRIKARRKMADLH-AVPRGMYDGPVFD 505
BLAST of Dihydropyrimidinase vs. UniProt/SwissProt
Match: sp|Q62188|DPYL3_MOUSE (Dihydropyrimidinase-related protein 3 OS=Mus musculus OX=10090 GN=Dpysl3 PE=1 SV=1) HSP 1 Score: 298.13 bits (762), Expect = 2.102e-91 Identity = 174/505 (34.46%), Postives = 279/505 (55.25%), Query Frame = 2
Query: 149 TQKKLLIKCGTVINHDCTYDADVLIENGKIVNIAKN-IEDSLAECIDATGCFVLPGGVDAETNFAAKRGGIVSPENYFSGTKAAIYGGTTTVVNCLEIMKDESLKEKYEMEKDIISKEIVCNLAIQLCLPEVNEAIKSEFNELLQSKSVVP-LVRLSTVDKGCHCVKIDDEELYDALCWCRDNSVLPTVHAENDKMVAILEKELLADGVTGPEGHYLSRPEKVEDEAVFRVLTIAEMVKCPIHFGKVYAKSSLDKIMDWQRKSSNTIICGTSLVALVHNAEKYRDPNWKVAASFVTMPALKMNKTTEFQCTELLETVASRKINHVASSHLVFDMKHKASGRNDFRCIIPGTNGVQYRMKILWDKAVKSGRMEPTSFVNCVSTTPAKLANIYPHKGTISIGSDADIIVWKGDS---VSHSNFEA-GDINVFEDVICHSGPKYVIVNGIVVLDHEGNFTASKGSGQIVSPSLETMNSYFQKQLINYKLSHEVEKKIAREPYDGPVID 1645
T +LLIK G ++N D ++ AD+ +E+G I I N I + I+A G V+PGG+D T+F G+ + +++F GTKAA+ GGTT +++ + + SL E YE ++ + C+ A+ + + N+++K E L + K V +V ++ D ++ + ELY+ + + VHAEN ++A + +L G+TGPEGH LSRPE++E EAVFR +T+A CP++ KV +KS+ D ++ RK N + +L + Y NW AA+FVT P L + TT LL AS + S+H F KA G+++F I GTNGV+ RM ++WDKAV +G+M+ FV ST AK+ N+YP KG I++GSD+D+++W D+ VS N ++ + N+FE + P VI G ++L+ +GN ++G+G+ + S + Y K++ + ++ + R YDGPV D
Sbjct: 13 TSDRLLIKGGRIVNDDQSFYADIYMEDGLIKQIGDNLIVPGGVKTIEANGKMVIPGGIDVHTHFQMPYKGMTTVDDFFQGTKAALAGGTTMIIDHVVPEPESSLTEAYEKWREWADGKSCCDYALHVDITHWNDSVKQEVQSLSKEKGVNSFMVYMAYKD----LYQVSNTELYEIFTCLGELGAIAQVHAENGDIIAQEQARMLEMGITGPEGHVLSRPEELEAEAVFRAITVASQTNCPLYVTKVMSKSAAD-LISQARKKGNVVFGEPITASLGIDGTHYWSKNWAKAAAFVTSPPLSPDPTTPDYINSLL---ASGDLQLSGSAHCTFSTAQKAIGKDNFTAIPEGTNGVEERMSVIWDKAVATGKMDENQFVAVTSTNAAKIFNLYPRKGRIAVGSDSDLVIWDPDALKIVSAKNHQSVAEYNIFEGMELRGAPLVVICQGKIMLE-DGNLHVTQGAGRFIPCS--PFSDYVYKRIKARRKMADLH-AVPRGMYDGPVFD 505
BLAST of Dihydropyrimidinase vs. UniProt/SwissProt
Match: sp|Q6GL72|DPYL3_XENTR (Dihydropyrimidinase-related protein 3 OS=Xenopus tropicalis OX=8364 GN=dpysl3 PE=2 SV=1) HSP 1 Score: 296.59 bits (758), Expect = 7.743e-91 Identity = 173/506 (34.19%), Postives = 278/506 (54.94%), Query Frame = 2
Query: 149 TQKKLLIKCGTVINHDCTYDADVLIENGKIVNIAKN-IEDSLAECIDATGCFVLPGGVDAETNFAAKRGGIVSPENYFSGTKAAIYGGTTTVVNCLEIMKDESLKEKYEMEKDIISKEIVCNLAIQLCLPEVNEAIKSEFNELLQSKSVVP-LVRLSTVDKGCHCVKIDDEELYDALCWCRDNSVLPTVHAENDKMVAILEKELLADGVTGPEGHYLSRPEKVEDEAVFRVLTIAEMVKCPIHFGKVYAKSSLDKIMDWQRKSSNTIICGTSLVA-LVHNAEKYRDPNWKVAASFVTMPALKMNKTTEFQCTELLETVASRKINHVASSHLVFDMKHKASGRNDFRCIIPGTNGVQYRMKILWDKAVKSGRMEPTSFVNCVSTTPAKLANIYPHKGTISIGSDADIIVWKGDSV----SHSNFEAGDINVFEDVICHSGPKYVIVNGIVVLDHEGNFTASKGSGQIVSPSLETMNSYFQKQLINYKLSHEVEKKIAREPYDGPVID 1645
T +LLIK G ++N D ++ AD+ +E+G I I N I + I+A G V+PGG+D T+ G+ + +++F GTKAA+ GGTT +V+ + + SL E +E ++ + C+ ++ + + N+++K E L++ K V +V ++ D ++ + ELY+ + + VHAEN ++A + +L G+TGPEGH LSRPE++E EAVFR +TIA CP++ KV +KSS+D I Q + ++ G + A L + Y NW AA+FVT P L + TT LL AS + S+H F KA G+++F I GTNG++ RM ++WDKAV +G+M+ FV ST AK+ N+YP KG I++GSD+D+++W D+V + S+ A + N+FE + P VI G ++++ +G ++G+G+ + S Y K++ E+ + R YDGPV D
Sbjct: 13 TSDRLLIKGGRIVNDDQSFYADIYMEDGLIKQIGDNLIVPGGVKTIEANGKMVIPGGIDVHTHLQMPYRGMTTVDDFFQGTKAALAGGTTMIVDHVIPEPEASLTEAFEKWREWADGKTCCDYSLHVDITHWNDSVKQEVEALVKQKGVNSFMVYMAYKD----LYQMSNTELYEVFTFLGGLGAIAQVHAENGDIIAQEQNRMLELGITGPEGHVLSRPEELEAEAVFRAITIASQTNCPLYVTKVMSKSSVDLIS--QARKKGYVVFGEPITASLGTDGTHYWSKNWAKAAAFVTSPPLSPDPTTPDYINSLL---ASGDLQVTGSAHATFSTAQKAIGKDNFTLIPEGTNGIEERMSVIWDKAVATGKMDENQFVAVTSTNAAKIFNLYPRKGRIAVGSDSDLVIWDPDAVKIVSAKSHHSAAEYNIFEGMELRGAPLVVICQGKIMME-DGTLHVTQGTGRFIPCS--PFPDYVYKRIKARTKMAELH-AVPRGMYDGPVYD 505
BLAST of Dihydropyrimidinase vs. TrEMBL
Match: Q5DF26 (SJCHGC09277 protein OS=Schistosoma japonicum OX=6182 PE=2 SV=1) HSP 1 Score: 330.487 bits (846), Expect = 2.328e-101 Identity = 207/585 (35.38%), Postives = 310/585 (52.99%), Query Frame = 2
Query: 134 LFMSETQKKLLIKCGTVINHDCTYDADVLIENGKIVNIAKNIE-DSLAECIDATGCFVLPGGVDAETNFAAKRGGIVSPENYFSGTKAAIYGGTTTVVNCLEIMKDESLKEKYEMEKDIISKEIVCNLAIQLCLPEVNEAIKSEFNELLQSKSVVPL-VRLSTVDKGCHCVKIDDEELYDALCWCRDNSVLPTVHAENDKMVAILEKELLADGVTGPEGHYLSRPEKVEDEAVFRVLTIAEMVKCPIHFGKVYAKSSLDKIMDWQRKSSNTIICGTSLVALVHNAEKYRDPNWKVAASFVTMPALKMNKTTEFQCTELLETVASRKINHVASSHLVFDMKHKASGRNDFRCIIPGTNGVQYRMKILWDKAVKSGRMEPTSFVNCVSTTPAKLANIYPHKGTISIGSDADIIVWKGDSVS----HSNFEAGDINVFEDVICHSGPKYVIVNGIVVLDHEGNFTASKGSGQIVSPSLETMNSYFQKQLINYKLSHEVEKKIAREPYDGPV----IDPSAD---NKEEKHVLYSH---MVNNDVYKRGGP-AEDKKEALPPGQ----RVIRTSVKTAQPPGGSAQASW 1825
+ + +Q +LLIK G V+N D + AD+ IE+G I + + IDA+G V+PGG+D T F + G+ + ++++SGTKAA+ GGTTT++NC+ + SL + Y+ + + C+ A LP+ + + E L++ K V V LS + + IDD + ++ CRD + VHAEN K+V ILE ++ DG+TGPEG S PE E EA R L++AE CP++ +V + + +I R N ++ T AL + Y+ W+ AA +V P L+ N T EL+ V++ + AS H F KA G++DFR I PG NGV+ RM I+W+K V SG M+P FV ST AK+ ++YPHKG I +GSDAD+++W GD SN E D N+FE + CH P VI G VVL+ +G ++G+G+ V S + + Y ++ L V K + R+PY GPV I P+A N EK + S + + GG ++ +L Q R +RT ++T QPPGG++ A W
Sbjct: 1 MHLQSSQNRLLIKGGKVVNDDRMFTADIYIEDGVIRQVGNQLSIPGGVRIIDASGKMVIPGGIDPHTCFESSCFGLNTSDDFYSGTKAALAGGTTTIINCI-MPTQSSLLDMYDKCRQAADAKACCDYAFHFVLPQYDPKVSKEMELLVKEKGVNSFRVFLSNTNN----MLIDDGDFFEVAKRCRDLGAILQVHAENGKLVKILESKIYNDGITGPEGCLYSHPEMAEVEATHRALSLAESAVCPLYILQVTSTKAAHQISK-ARWRGNAVVGETLAAALGADGTHYKHNCWRHAAGYVLSPPLRANPCTP---EELMRYVSTGVLECTASGHCTFKADQKALGKDDFRKIPPGVNGVEDRMSIVWEKGVMSGFMDPCKFVAVTSTNAAKVFSLYPHKGRIDVGSDADLVIWDGDMTRTISVKSNHENVDFNIFEGLHCHGVPLVVITAGRVVLE-DGELRVTQGAGRFVPAS--SFSPYIFERTKRLALMRSV-KPVVRDPYSGPVSAEFIVPTAGIVTNGTEKVPVGSDGDGLRPRSPTRSGGRNMQESSFSLSGAQYDDSRPLRTGIRTKQPPGGASNALW 572
BLAST of Dihydropyrimidinase vs. TrEMBL
Match: A0A4Z2DJ15 (Dihydropyrimidinase-related protein isoform 3 OS=Schistosoma japonicum OX=6182 GN=EWB00_000398 PE=4 SV=1) HSP 1 Score: 330.487 bits (846), Expect = 3.470e-101 Identity = 207/585 (35.38%), Postives = 310/585 (52.99%), Query Frame = 2
Query: 134 LFMSETQKKLLIKCGTVINHDCTYDADVLIENGKIVNIAKNIE-DSLAECIDATGCFVLPGGVDAETNFAAKRGGIVSPENYFSGTKAAIYGGTTTVVNCLEIMKDESLKEKYEMEKDIISKEIVCNLAIQLCLPEVNEAIKSEFNELLQSKSVVPL-VRLSTVDKGCHCVKIDDEELYDALCWCRDNSVLPTVHAENDKMVAILEKELLADGVTGPEGHYLSRPEKVEDEAVFRVLTIAEMVKCPIHFGKVYAKSSLDKIMDWQRKSSNTIICGTSLVALVHNAEKYRDPNWKVAASFVTMPALKMNKTTEFQCTELLETVASRKINHVASSHLVFDMKHKASGRNDFRCIIPGTNGVQYRMKILWDKAVKSGRMEPTSFVNCVSTTPAKLANIYPHKGTISIGSDADIIVWKGDSVS----HSNFEAGDINVFEDVICHSGPKYVIVNGIVVLDHEGNFTASKGSGQIVSPSLETMNSYFQKQLINYKLSHEVEKKIAREPYDGPV----IDPSAD---NKEEKHVLYSH---MVNNDVYKRGGP-AEDKKEALPPGQ----RVIRTSVKTAQPPGGSAQASW 1825
+ + +Q +LLIK G V+N D + AD+ IE+G I + + IDA+G V+PGG+D T F + G+ + ++++SGTKAA+ GGTTT++NC+ + SL + Y+ + + C+ A LP+ + + E L++ K V V LS + + IDD + ++ CRD + VHAEN K+V ILE ++ DG+TGPEG S PE E EA R L++AE CP++ +V + + +I R N ++ T AL + Y+ W+ AA +V P L+ N T EL+ V++ + AS H F KA G++DFR I PG NGV+ RM I+W+K V SG M+P FV ST AK+ ++YPHKG I +GSDAD+++W GD SN E D N+FE + CH P VI G VVL+ +G ++G+G+ V S + + Y ++ L V K + R+PY GPV I P+A N EK + S + + GG ++ +L Q R +RT ++T QPPGG++ A W
Sbjct: 15 MHLQSSQNRLLIKGGKVVNDDRMFTADIYIEDGVIRQVGNQLSIPGGVRIIDASGKMVIPGGIDPHTCFESSCFGLNTSDDFYSGTKAALAGGTTTIINCI-MPTQSSLLDMYDKCRQAADAKACCDYAFHFVLPQYDPKVSKEMELLVKEKGVNSFRVFLSNTNN----MLIDDGDFFEVAKRCRDLGAILQVHAENGKLVKILESKIYNDGITGPEGCLYSHPEMAEVEATHRALSLAESAVCPLYILQVTSTKAAHQISK-ARWRGNAVVGETLAAALGADGTHYKHNCWRHAAGYVLSPPLRANPCTP---EELMRYVSTGVLECTASGHCTFKADQKALGKDDFRKIPPGVNGVEDRMSIVWEKGVMSGFMDPCKFVAVTSTNAAKVFSLYPHKGRIDVGSDADLVIWDGDMTRTISVKSNHENVDFNIFEGLHCHGVPLVVITAGRVVLE-DGELRVTQGAGRFVPAS--SFSPYIFERTKRLALMRSV-KPVVRDPYSGPVSAEFIVPTAGIVTNGTEKVPVGSDGDGLRPRSPTRSGGRNMQESSFSLSGAQYDDSRPLRTGIRTKQPPGGASNALW 586
BLAST of Dihydropyrimidinase vs. TrEMBL
Match: C1L524 (Dihydropyrimidinase-like 2 OS=Schistosoma japonicum OX=6182 GN=DPYSL2 PE=2 SV=1) HSP 1 Score: 330.487 bits (846), Expect = 3.470e-101 Identity = 207/585 (35.38%), Postives = 310/585 (52.99%), Query Frame = 2
Query: 134 LFMSETQKKLLIKCGTVINHDCTYDADVLIENGKIVNIAKNIE-DSLAECIDATGCFVLPGGVDAETNFAAKRGGIVSPENYFSGTKAAIYGGTTTVVNCLEIMKDESLKEKYEMEKDIISKEIVCNLAIQLCLPEVNEAIKSEFNELLQSKSVVPL-VRLSTVDKGCHCVKIDDEELYDALCWCRDNSVLPTVHAENDKMVAILEKELLADGVTGPEGHYLSRPEKVEDEAVFRVLTIAEMVKCPIHFGKVYAKSSLDKIMDWQRKSSNTIICGTSLVALVHNAEKYRDPNWKVAASFVTMPALKMNKTTEFQCTELLETVASRKINHVASSHLVFDMKHKASGRNDFRCIIPGTNGVQYRMKILWDKAVKSGRMEPTSFVNCVSTTPAKLANIYPHKGTISIGSDADIIVWKGDSVS----HSNFEAGDINVFEDVICHSGPKYVIVNGIVVLDHEGNFTASKGSGQIVSPSLETMNSYFQKQLINYKLSHEVEKKIAREPYDGPV----IDPSAD---NKEEKHVLYSH---MVNNDVYKRGGP-AEDKKEALPPGQ----RVIRTSVKTAQPPGGSAQASW 1825
+ + +Q +LLIK G V+N D + AD+ IE+G I + + IDA+G V+PGG+D T F + G+ + ++++SGTKAA+ GGTTT++NC+ + SL + Y+ + + C+ A LP+ + + E L++ K V V LS + + IDD + ++ CRD + VHAEN K+V ILE ++ DG+TGPEG S PE E EA R L++AE CP++ +V + + +I R N ++ T AL + Y+ W+ AA +V P L+ N T EL+ V++ + AS H F KA G++DFR I PG NGV+ RM I+W+K V SG M+P FV ST AK+ ++YPHKG I +GSDAD+++W GD SN E D N+FE + CH P VI G VVL+ +G ++G+G+ V S + + Y ++ L V K + R+PY GPV I P+A N EK + S + + GG ++ +L Q R +RT ++T QPPGG++ A W
Sbjct: 15 MHLQSSQNRLLIKGGKVVNDDRMFTADIYIEDGVIRQVGNQLSIPGGVRIIDASGKMVIPGGIDPHTCFESSCFGLNTSDDFYSGTKAALAGGTTTIINCI-MPTQSSLLDMYDKCRQAADAKACCDYAFHFVLPQYDPKVSKEMELLVKEKGVNSFRVFLSNTNN----MLIDDGDFFEVAKRCRDLGAILQVHAENGKLVKILESKIYNDGITGPEGCLYSHPEMAEVEATHRALSLAESAVCPLYILQVTSTKAAHQISK-ARWRGNAVVGETLAAALGADGTHYKHNCWRHAAGYVLSPPLRANPCTP---EELMRYVSTGVLECTASGHCTFKADQKALGKDDFRKIPPGVNGVEDRMSIVWEKGVMSGFMDPCKFVAVTSTNAAKVFSLYPHKGRIDVGSDADLVIWDGDMTRTISVKSNHENVDFNIFEGLHCHGVPLVVITAGRVVLE-DGELRVTQGAGRFVPAS--SFSPYIFERTKRLALMRSV-KPVVRDPYSGPVSAEFIVPTAGIVTNGTEKVPVGSDGDGLRPRSPTRSGGRNMQESSFSLSGAQYDDSRPLRTGIRTKQPPGGASNALW 586
BLAST of Dihydropyrimidinase vs. TrEMBL
Match: A0A183QW39 (Amidohydro-rel domain-containing protein OS=Schistosoma rodhaini OX=6188 PE=4 SV=1) HSP 1 Score: 320.472 bits (820), Expect = 2.378e-97 Identity = 196/594 (33.00%), Postives = 313/594 (52.69%), Query Frame = 2
Query: 134 LFMSETQKKLLIKCGTVINHDCTYDADVLIENGKIVNIAKNIE-DSLAECIDATGCFVLPGGVDAETNFAAKRGGIVSPENYFSGTKAAIYGGTTTVVNCLEIMKDESLKEKYEMEKDIISKEIVCNLAIQLCLPEVNEAIKSEFNELLQSKSVVPL-VRLSTVDKGCHCVKIDDEELYDALCWCRDNSVLPTVHAENDKMVAILEKELLADGVTGPEGHYLSRPEKVEDEAVFRVLTIAEMVKCPIHFGKVYAKSSLDKIMD--WQRKSSNTIICGTSLVALVHNAEKYRDPNWKVAASFVTMPALKMNKTTEFQCTELLETVASRKINHVASSHLVFDMKHKASGRNDFRCIIPGTNGVQYRMKILWDKAVKSGRMEPTSFVNCVSTTPAKLANIYPHKGTISIGSDADIIVWKGDSV----SHSNFEAGDINVFEDVICHSGPKYVIVNGIVVLDHEGNFTASKGSGQIVSPSLETMNSYFQKQLINYKLSHEVEKKIAREPYDGPVIDPSADNKEEKHVLYSHMVNNDVYKR--GGPAEDKKEALPP--------------------GQRVIRTSVKTAQPPGGSAQASW 1825
+ + +Q +LLIK G V+N D + AD+ IE+G I + + I+A+G V+PGGVD T + G+ + ++++SGT+AA+ GGTTT++NC+ K SL + YE + + C+ ++ L + + I E L++ K V V LS + + +DD + ++ C+D + VHAEN K+V ILE ++ DG+TGPEG+ S PE E EA R +++A+ CP++ +V + + D+I + W R N ++ T AL + Y++ W+ +A +V P L++N T +L+ V++ + AS H F + KA G++DFR I PG NGV+ RM ++W++ V SG ++P FV ST AK+ N+YPHKG I +GSDAD+++W GD+ + +N E D N+FE + CH P VI G VVL+ +G ++G+G+ V P+L + Y ++ L + K + R+ Y GP+ + E + +VNN K G AE + P R IRT ++T QPPGG++ A W
Sbjct: 15 MHLQSSQNRLLIKGGKVVNDDRMFTADIYIEDGVIRQVGSQLSIPGGVRIIEASGKMVIPGGVDPHTCLDSSCFGLDTSDDFYSGTRAALAGGTTTIINCIVPTK-SSLLDMYEKSRQAADSKACCDYSMHFILSQYDSKISKEMELLVKEKGVNSFRVFLSNTND----MLVDDGDFFEIAKRCKDLGAVLQVHAENGKLVKILESKIYNDGITGPEGYLYSHPEMAEIEATHRAISLADAAGCPLYILQVTSPKAADQISEARWNR---NVVVGETLAAALGADGTHYKNSCWRHSAGYVLSPPLRINPNTP---DKLMRYVSTGVLECTASGHCTFKTEQKAVGKDDFRKIPPGVNGVEDRMSVVWERGVMSGFIDPCKFVAVTSTNAAKVFNLYPHKGRIDVGSDADLVIWDGDATRTISAKNNHENVDFNIFEGLQCHGVPVVVISAGRVVLE-DGELRVTQGAGRFV-PALP-FSPYIFERTKRLALMRSI-KPVIRDSYTGPI------STEFTGPMKDGIVNNGTEKASVGSDAEGLRPRSPTRSGGRNMQESSFSLSGAQYDDSRPIRTGIRTKQPPGGASNALW 587
BLAST of Dihydropyrimidinase vs. TrEMBL
Match: H2STX2 (Collapsin response mediator protein 1 OS=Takifugu rubripes OX=31033 GN=LOC101061532 PE=4 SV=1) HSP 1 Score: 320.087 bits (819), Expect = 3.010e-97 Identity = 198/576 (34.38%), Postives = 305/576 (52.95%), Query Frame = 2
Query: 149 TQKKLLIKCGTVINHDCTYDADVLIENGKIVNIAKNIE-DSLAECIDATGCFVLPGGVDAETNFAAKRGGIVSPENYFSGTKAAIYGGTTTVVNCLEIMKDESLKEKYEMEKDIISKEIVCNLAIQLCLPEVNEAIKSEFNELLQSKSVVPL-VRLSTVDKGCHCVKIDDEELYDALCWCRDNSVLPTVHAENDKMVAILEKELLADGVTGPEGHYLSRPEKVEDEAVFRVLTIAEMVKCPIHFGKVYAKSSLDKIMDWQRKSSNTIICGTSLVA-LVHNAEKYRDPNWKVAASFVTMPALKMNKTTEFQCTELLETVASRKINHVASSHLVFDMKHKASGRNDFRCIIPGTNGVQYRMKILWDKAVKSGRMEPTSFVNCVSTTPAKLANIYPHKGTISIGSDADIIVWKGDSV----SHSNFEAGDINVFEDVICHSGPKYVIVNGIVVLDHEGNFTASKGSGQIVSPSLETMNSYFQKQLINYKLSHEVEKKIAREPYDGPVID-----------PSADNKEEKH-------------VLYSHMVNNDVYKRGGPAEDKKEALPPGQRVIRTSV 1783
T +K+LIK G V+N D ++ ADV IE+G I + +++ + I+A G V+PGG+D T G +++ GTKAAI GGTT +++ + ESL E +E ++ K+ C+ ++ + +P+ NEA+K E L+ K + V ++ D ++ D ELY+A + + + VHAEN ++A +K++L G+TGPEGH LSRPE++E EAVFR +T+ V CP++ KV +KS+ D I +RK S ++ G + A L + Y NW AA++VT P L + TT LL A + V S+H ++ KA G++DF I GTNGV+ RM +WDKAV G+M+ FV ST AK+ N+YP KG I++GSDAD+++W DSV + + A D N+FE + C GP V+ G VV + EGN +G+G+ + P + + +Q+ + + V + + R YDGPV D PSA H L +++++ +R G + PPG R TS+
Sbjct: 16 TSEKVLIKGGRVVNDDQSFYADVYIEDGLIKQVGEDLALPGDVKVIEANGRMVMPGGIDVNTCLMKPYLGTRPVDDFCQGTKAAITGGTTMIIDHVTPQPGESLLEAFECWQEAADKKACCDYSLHVDIPQWNEAVKDELELLVHEKGINSFQVYMAYKD----VYQLSDSELYEAFSFLKQLGAVVLVHAENGDLIAQEQKKILGMGITGPEGHPLSRPEELEAEAVFRAITLGSRVNCPVYITKVMSKSAADTITQARRKGS--VVFGEPITASLATDGSHYFSKNWAKAAAYVTSPPLSPDPTTPDHLHTLL---ACGDLQVVGSAHCAYNTSQKAIGKDDFTLIPEGTNGVEERMGFVWDKAVAMGKMDENQFVAVTSTNAAKIFNLYPRKGRIAMGSDADVVIWDPDSVKTITARTQQSASDYNIFEGLECRGGPALVLSQGRVVYE-EGNLQVQQGTGRFI-PRKQFPDYAYQR--VKCRNQVRVNQGVMRGMYDGPVYDMVPTPKYITPAPSAKTSPTSHQPPPIRNLHQSNFSLSGAQIDDNIPRRSG----HRIVAPPGGRSNITSL 574
BLAST of Dihydropyrimidinase vs. Ensembl Cavefish
Match: dpysl5a (dihydropyrimidinase like 5 [Source:NCBI gene;Acc:103037842]) HSP 1 Score: 293.893 bits (751), Expect = 9.302e-91 Identity = 188/567 (33.16%), Postives = 293/567 (51.68%), Query Frame = 2
Query: 158 KLLIKCGTVINHDCTYDADVLIENGKIVNIAKNIE-DSLAECIDATGCFVLPGGVDAETNFAAKRGGIVSPENYFSGTKAAIYGGTTTVVNCLEIMKDESLKEKYEMEKDIISKEIVCNLAIQLCLPEVNEAIKSEFNELLQSKSVVPLVRLSTVDKGCHCVKIDDEELYDALCWCRDNSVLPTVHAENDKMVAILEKELLADGVTGPEGHYLSRPEKVEDEAVFRVLTIAEMVKCPIHFGKVYAKSSLDKIMDWQRKSSNTIICGTSLVALVHNAEKYRDPNWKVAASFVTMPALKMNKTTEFQCTELLETVASRKINHVASSHLVFDMKHKASGRNDFRCIIPGTNGVQYRMKILWDKAVKSGRMEPTSFVNCVSTTPAKLANIYPHKGTISIGSDADIIVWKGDSVS----HSNFEAGDINVFEDVICHSGPKYVIVNGIVVLDHEGNFTASKGSGQIVSPSLETMNSYFQKQLINYKLSHEVEKKIAREPYDGPVIDPSADNKEEKHVLYSHMVNNDVYKRGGPAEDKKEALPPGQRVI------RTSVKTAQPPGGSAQASW 1825
++LIK G V+N D T +ADV IENG I + K + A+ IDATG VLPGG+D + + ++++SGTKAA+ GGTT V+ + K+ESL + YE + + C+ A+ + + ++++ L++ K V ++ K + ++ D EL+ AL C+D + VHAEN ++VA KE L G++GPEG +SRPE++E EAV R +TIA CPI+ V + S+ D ++ + + TS V N +Y +W AA++VT+P L+++ T LL + + +N V S H F K KA G++DF I G GVQ RM I+W+K V G+M+ FV S+ AK+ N+YP KG I G+DAD++VW D+ + ++ GD+N++E + CH P I G VV ++ G FT ++GSG+ L T Y K+++ + + K + R PY G V K+E + + GG + + + I R+S + PPGG + W
Sbjct: 9 RILIKGGKVVNDDYTQEADVYIENGIIQQVGKELMIPGGAKVIDATGKLVLPGGIDTSVHLQETFMNATTADDFYSGTKAALAGGTTMVIGHVLPEKNESLLDAYEKCRSHADAKSCCDYALHVAVTWWGPKVRAQMETLVREKGVNSF-QMFMAYKDVYMLR--DSELFQALQNCKDIGAIARVHAENGELVAEGAKEALDLGISGPEGIEISRPEELEAEAVHRAITIANRAHCPIYLVNVSSMSAGD-VLATAKMQGKVVHGETSTAHAVINGLQYYHQDWAHAAAYVTVPPLRLDPNTP---NFLLSLLGNDSLNVVTSDHRPFTTKQKAMGKDDFTKIPHGVPGVQDRMSIIWEKGVVGGKMDENRFVAVTSSNAAKIYNLYPRKGRIIPGADADVVVWDPDATRTISVTTQWQGGDVNLYEGLRCHGVPLVTISRGRVVYEN-GIFTCAEGSGKFY--PLRTFPDYLYKKMVQREKCQAL-KGVDRAPYIGDVAAVQNSGKKETVPAVGDLAQRPCTRHGGMRDLHESSFSLSGVQIDDNLPKRSSQRILAPPGGRSSGIW 564
BLAST of Dihydropyrimidinase vs. Ensembl Cavefish
Match: dpysl4 (dihydropyrimidinase like 4 [Source:NCBI gene;Acc:103040013]) HSP 1 Score: 293.123 bits (749), Expect = 2.203e-90 Identity = 176/507 (34.71%), Postives = 276/507 (54.44%), Query Frame = 2
Query: 149 TQKKLLIKCGTVINHDCTYDADVLIENGKIVNIAKN-IEDSLAECIDATGCFVLPGGVDAETNFAAKRGGIVSPENYFSGTKAAIYGGTTTVVNCLEIMKDESLKEKYEMEKDIISKEIVCNLAIQLCLPEVNEAIKSEFNELLQSKSVVP-LVRLSTVDKGCHCVKIDDEELYDALCWCRDNSVLPTVHAENDKMVAILEKELLADGVTGPEGHYLSRPEKVEDEAVFRVLTIAEMVKCPIHFGKVYAKSSLDKIMDWQRKSSNTIICGTSLVA-LVHNAEKYRDPNWKVAASFVTMPALKMNKTTEFQCTELLETVASRKINHVASSHLVFDMKHKASGRNDFRCIIPGTNGVQYRMKILWDKAVKSGRMEPTSFVNCVSTTPAKLANIYPHKGTISIGSDADIIVW-----KGDSVSHSNFEAGDINVFEDVICHSGPKYVIVNGIVVLDHEGNFTASKGSGQIVSPSLETMNSYFQKQLINYKLSHEVEKKIAREPYDGPVID 1645
T KL+IK G ++N D ++ AD+ IE+G I I +N I S + +DA G V+PGG+D T+ A+ G+ ++++ GT+AA+ GGTT +++ + SL ++ +D+ K C+ ++ + + +E + E L++ + V LV +S D+ + D ++Y+ RD + VHAEN ++ +K LL G+TGPEGH LS PE+VE EAV+R +TIA+ CP++ KV ++ + D I ++K +I G + A L + Y NW AA+FV P L + T +L + + AS+H F KA G+++F I GTNG++ RM I+WDKAV SG+M+ FV ST AK+ N+YP KG I++GSDAD+++W K S + N ++N+FED+ C P VI G +VL+ +G A +GSG+ V + Y K++ E + + R YDGPV D
Sbjct: 13 TGDKLIIKGGKIVNDDQSFYADIFIEDGTIKQIGENLIVPSGVKTVDAYGHIVIPGGIDVNTSLQAQHMGMSPADDFYHGTRAALAGGTTMIIDHVVPEPGASLLAAFDQWRDVADKRSCCDYSLHIDITRWHEGMFEELETLVKDQGVNSFLVFMSYKDR----FQSSDSQMYEIFGILRDLGAIAQVHAENGDIIDEEQKRLLDMGITGPEGHVLSHPEEVETEAVYRAITIAKQANCPLYITKVMSRPAADVIAKARKK--GMVIYGEPIAASLGTDGSHYWSQNWAKAAAFVMSPPLSPDPATPDYLNSML---SCGDLQVTASAHCTFSTAQKAVGKDNFTLIPEGTNGIEERMSIVWDKAVASGKMDENEFVAVTSTNAAKIFNLYPRKGRIAVGSDADLVIWNTKETKTFSATSHNLTV-EMNIFEDMECRGFPVVVISQGRIVLE-DGKLDAMEGSGRFV--PRKAFPDYVYKRIKARSRMAEA-RGVPRGNYDGPVHD 505
BLAST of Dihydropyrimidinase vs. Ensembl Cavefish
Match: dpysl4 (dihydropyrimidinase like 4 [Source:NCBI gene;Acc:103040013]) HSP 1 Score: 292.738 bits (748), Expect = 4.002e-89 Identity = 175/504 (34.72%), Postives = 275/504 (54.56%), Query Frame = 2
Query: 158 KLLIKCGTVINHDCTYDADVLIENGKIVNIAKN-IEDSLAECIDATGCFVLPGGVDAETNFAAKRGGIVSPENYFSGTKAAIYGGTTTVVNCLEIMKDESLKEKYEMEKDIISKEIVCNLAIQLCLPEVNEAIKSEFNELLQSKSVVP-LVRLSTVDKGCHCVKIDDEELYDALCWCRDNSVLPTVHAENDKMVAILEKELLADGVTGPEGHYLSRPEKVEDEAVFRVLTIAEMVKCPIHFGKVYAKSSLDKIMDWQRKSSNTIICGTSLVA-LVHNAEKYRDPNWKVAASFVTMPALKMNKTTEFQCTELLETVASRKINHVASSHLVFDMKHKASGRNDFRCIIPGTNGVQYRMKILWDKAVKSGRMEPTSFVNCVSTTPAKLANIYPHKGTISIGSDADIIVW-----KGDSVSHSNFEAGDINVFEDVICHSGPKYVIVNGIVVLDHEGNFTASKGSGQIVSPSLETMNSYFQKQLINYKLSHEVEKKIAREPYDGPVID 1645
KL+IK G ++N D ++ AD+ IE+G I I +N I S + +DA G V+PGG+D T+ A+ G+ ++++ GT+AA+ GGTT +++ + SL ++ +D+ K C+ ++ + + +E + E L++ + V LV +S D+ + D ++Y+ RD + VHAEN ++ +K LL G+TGPEGH LS PE+VE EAV+R +TIA+ CP++ KV ++ + D I ++K +I G + A L + Y NW AA+FV P L + T +L + + AS+H F KA G+++F I GTNG++ RM I+WDKAV SG+M+ FV ST AK+ N+YP KG I++GSDAD+++W K S + N ++N+FED+ C P VI G +VL+ +G A +GSG+ V + Y K++ E + + R YDGPV D
Sbjct: 119 KLIIKGGKIVNDDQSFYADIFIEDGTIKQIGENLIVPSGVKTVDAYGHIVIPGGIDVNTSLQAQHMGMSPADDFYHGTRAALAGGTTMIIDHVVPEPGASLLAAFDQWRDVADKRSCCDYSLHIDITRWHEGMFEELETLVKDQGVNSFLVFMSYKDR----FQSSDSQMYEIFGILRDLGAIAQVHAENGDIIDEEQKRLLDMGITGPEGHVLSHPEEVETEAVYRAITIAKQANCPLYITKVMSRPAADVIAKARKK--GMVIYGEPIAASLGTDGSHYWSQNWAKAAAFVMSPPLSPDPATPDYLNSML---SCGDLQVTASAHCTFSTAQKAVGKDNFTLIPEGTNGIEERMSIVWDKAVASGKMDENEFVAVTSTNAAKIFNLYPRKGRIAVGSDADLVIWNTKETKTFSATSHNLTV-EMNIFEDMECRGFPVVVISQGRIVLE-DGKLDAMEGSGRFV--PRKAFPDYVYKRIKARSRMAEA-RGVPRGNYDGPVHD 608
BLAST of Dihydropyrimidinase vs. Ensembl Cavefish
Match: crmp1 (collapsin response mediator protein 1 [Source:ZFIN;Acc:ZDB-GENE-050720-1]) HSP 1 Score: 285.804 bits (730), Expect = 3.750e-88 Identity = 170/511 (33.27%), Postives = 271/511 (53.03%), Query Frame = 2
Query: 137 FMSETQKKLLIKCGTVINHDCTYDADVLIENGKIVNIAKN-IEDSLAECIDATGCFVLPGGVDAETNFAAKRGGIVSPENYFSGTKAAIYGGTTTVVNCLEIMKDESLKEKYEMEKDIISKEIVCNLAIQLCLPEVNEAIKSEFNELLQSKSVVPL-VRLSTVDKGCHCVKIDDEELYDALCWCRDNSVLPTVHAENDKMVAILEKELLADGVTGPEGHYLSRPEKVEDEAVFRVLTIAEMVKCPIHFGKVYAKSSLDKIMDWQRKSSNTIICGTSLVA-LVHNAEKYRDPNWKVAASFVTMPALKMNKTTEFQCTELLETVASRKINHVASSHLVFDMKHKASGRNDFRCIIPGTNGVQYRMKILWDKAVKSGRMEPTSFVNCVSTTPAKLANIYPHKGTISIGSDADIIVWKGDSV----SHSNFEAGDINVFEDVICHSGPKYVIVNGIVVLDHEGNFTASKGSGQIVS---------PSLETMNSYFQKQLINYKLSHEVEKKIARE 1621
+ ++LLIK G V+N D ++ ADV +E+G I + +N I ++A G V+PGG+D T G + +++F GTKAA+ GGTT +++ + SL +E + ++ C+ ++ + +P+ + +K E L+Q K + V ++ D ++ + +LY+AL RD + VHAEN +VA +K++L+ G+TGPEGH LS PE++E EAVFR +TI V CPI+ +V +K++ D + +RK ++ G L A L + Y NW AA++V P L + TT + L T+ + + V S H + KA G+++F I GTNGV+ RM +WD+AV G+M+ FV ST AKL N+YP KG I++GSDADI++W D V + A + N+FE + C P +VI G VV + +G +G+G+ + + T N + L Y L +V+ + R
Sbjct: 12 LLHHMGEQLLIKGGRVVNDDQSFYADVYVEDGVIRQVGENLIVPGGVRVVEADGRMVIPGGIDTNTCLHKDYLGSLPVDDFFQGTKAALAGGTTMIIDHVTPQPGASLLHAFEQWQAAADRKCCCDYSLHVDIPQWDGGVKDELEVLVQEKGINSFQVYMAYKD----LFQMTNSQLYEALSCLRDLGAVVLVHAENGDLVAQEQKKILSMGITGPEGHPLSHPEELEAEAVFRAITIGNQVNCPIYITRVMSKTAADTLAQARRKGC--VVFGEPLTASLATDGSHYWSRNWAKAAAYVISPPLSPDPTTP----QHLHTMLTGDLQVVGSGHCAYSTAQKAIGKDNFTLIPEGTNGVEERMGFVWDRAVALGKMDENQFVAVTSTNAAKLFNLYPRKGRIAVGSDADIVIWDPDHVKTITAKLQQSALEYNIFEGMECRGVPVFVISQGRVVYE-DGKLNVQQGTGRFIPRKPFPDHAYQRINTRNKLYVIYLYVYILGAQVDDNVPRR 511
BLAST of Dihydropyrimidinase vs. Ensembl Cavefish
Match: crmp1 (collapsin response mediator protein 1 [Source:ZFIN;Acc:ZDB-GENE-050720-1]) HSP 1 Score: 283.108 bits (723), Expect = 3.619e-87 Identity = 171/507 (33.73%), Postives = 270/507 (53.25%), Query Frame = 2
Query: 149 TQKKLLIKCGTVINHDCTYDADVLIENGKIVNIAKN-IEDSLAECIDATGCFVLPGGVDAETNFAAKRGGIVSPENYFSGTKAAIYGGTTTVVNCLEIMKDESLKEKYEMEKDIISKEIVCNLAIQLCLPEVNEAIKSEFNELLQSKSVVPL-VRLSTVDKGCHCVKIDDEELYDALCWCRDNSVLPTVHAENDKMVAILEKELLADGVTGPEGHYLSRPEKVEDEAVFRVLTIAEMVKCPIHFGKVYAKSSLDKIMDWQRKSSNTIICGTSLVA-LVHNAEKYRDPNWKVAASFVTMPALKMNKTTEFQCTELLETVASRKINHVASSHLVFDMKHKASGRNDFRCIIPGTNGVQYRMKILWDKAVKSGRMEPTSFVNCVSTTPAKLANIYPHKGTISIGSDADIIVWKGDSV----SHSNFEAGDINVFEDVICHSGPKYVIVNGIVVLDHEGNFTASKGSGQIVS---------PSLETMNSYFQKQLINYKLSHEVEKKIARE 1621
T ++LLIK G V+N D ++ ADV +E+G I + +N I ++A G V+PGG+D T G + +++F GTKAA+ GGTT +++ + SL +E + ++ C+ ++ + +P+ + +K E L+Q K + V ++ D ++ + +LY+AL RD + VHAEN +VA +K++L+ G+TGPEGH LS PE++E EAVFR +TI V CPI+ +V +K++ D + +RK ++ G L A L + Y NW AA++V P L + TT +L T ++ V S H + KA G+++F I GTNGV+ RM +WD+AV G+M+ FV ST AKL N+YP KG I++GSDADI++W D V + A + N+FE + C P +VI G VV + +G +G+G+ + + T N + L Y L +V+ + R
Sbjct: 13 TGEQLLIKGGRVVNDDQSFYADVYVEDGVIRQVGENLIVPGGVRVVEADGRMVIPGGIDTNTCLHKDYLGSLPVDDFFQGTKAALAGGTTMIIDHVTPQPGASLLHAFEQWQAAADRKCCCDYSLHVDIPQWDGGVKDELEVLVQEKGINSFQVYMAYKD----LFQMTNSQLYEALSCLRDLGAVVLVHAENGDLVAQEQKKILSMGITGPEGHPLSHPEELEAEAVFRAITIGNQVNCPIYITRVMSKTAADTLAQARRKGC--VVFGEPLTASLATDGSHYWSRNWAKAAAYVISPPLSPDPTTPQHLHTML-TCGDLQV--VGSGHCAYSTAQKAIGKDNFTLIPEGTNGVEERMGFVWDRAVALGKMDENQFVAVTSTNAAKLFNLYPRKGRIAVGSDADIVIWDPDHVKTITAKLQQSALEYNIFEGMECRGVPVFVISQGRVVYE-DGKLNVQQGTGRFIPRKPFPDHAYQRINTRNKLYVIYLYVYILGAQVDDNVPRR 509
BLAST of Dihydropyrimidinase vs. Ensembl Sea Lamprey
Match: dpysl3 (dihydropyrimidinase like 3 [Source:NCBI gene;Acc:553166]) HSP 1 Score: 226.098 bits (575), Expect = 6.135e-67 Identity = 144/459 (31.37%), Postives = 239/459 (52.07%), Query Frame = 2
Query: 497 EIVCNLAIQLCLPEVNEAIKSEFNELLQSKSVVP-LVRLSTVDKGCHCVKIDDEELYDALCWCRDNSVLPTVHAENDKMVAILEKELLADGVTGPEGHYLSRPEKVEDEAVFRVLTIAEMVKCPIHFGKVYAKSSLDKIMDWQRKSSNTIICGTSLVA-LVHNAEKYRDPNWKVAASFVTMPALKMNKTTEFQCTELLETVASRKINHVASSHLVFDMKHKASGRNDFRCIIPGTNGVQYRMKILWDKAVKSGRMEPTSFVNCVSTTPAKLANIYPHKGTISIGSDADIIVWKGDSVS----HSNFEAGDINVFEDVICHSGPKYVIVNGIVVLDHEGNFTASKGSGQIVSPSLETMNSYFQKQLINYKLSHEVEKKIAREPYDGPVIDPSADNKEEKHVLYSHMVNNDVYKRGGPAEDKKEALP-----------PGQRV-----IRTSVKTAQPPGG 1807
++ C+ ++ + +P+ +E + E L++ + + LV ++ D+ ++ D E+Y+ + RD + VHAEN ++A +K +L G+ GPEGH LSR E+VE EAV R ++IA CP++ KV +KS+ D I ++K + ++ G + A L + Y NW AA+FVT P L + TT LL + + S+H F KA G+++F I GTNG++ RM I+WDKAV +G+M+ FV ST AK+ ++YP KG I++GSDAD+++W+ D+++ ++ A + N+FE + P VI G +VL+ EG +A++G+G+ V P +++ KL+ + + R YDGPV + S+ + + S R PA+ ++ P G +V RT + PPGG
Sbjct: 27 KVCCDYSLHVAVPQWHEGVAEELEILVKDRGINSFLVYMAYKDQ----YQMSDTEMYEVFTFLRDIGAIAMVHAENGDIIAEEQKRILEMGIAGPEGHVLSRAEEVEAEAVNRAISIANHTNCPLYITKVMSKSAADVISQARKKGA--VVYGEPITASLGTDGSHYWSKNWAKAAAFVTSPPLSPDPTTPDYLNSLL---SCGDLQVTGSAHCTFTTAQKALGKDNFTLIPEGTNGIEERMSIVWDKAVATGKMDENQFVAVTSTNAAKIFSLYPRKGRIAVGSDADLVIWEPDTITTISAKTHTAAVEYNIFEGMEVRGAPLVVISQGRIVLE-EGKLSATQGAGRFV-PRKAFPEQVYKRIKARNKLAE--MRGVPRGLYDGPVFELSSSS------VRSTTATPTPSARTSPAKSAAQSAPLRNLHQSGFSLSGAQVDDELPRRTGHRIVAPPGG 466
BLAST of Dihydropyrimidinase vs. Ensembl Sea Lamprey
Match: dpysl2b (dihydropyrimidinase like 2b [Source:ZFIN;Acc:ZDB-GENE-031105-1]) HSP 1 Score: 154.066 bits (388), Expect = 7.719e-43 Identity = 92/265 (34.72%), Postives = 146/265 (55.09%), Query Frame = 2
Query: 158 KLLIKCGTVINHDCTYDADVLIENGKIVNIAKN-IEDSLAECIDATGCFVLPGGVDAETNFAAKRGGIVSPENYFSGTKAAIYGGTTTVVNCLEIMKDESLKEKYEMEKDIISKEIVCNLAIQLCLPEVNEAIKSEFNELLQSKSVVP-LVRLSTVDKGCHCVKIDDEELYDALCWCRDNSVLPTVHAENDKMVAILEKELLADGVTGPEGHYLSRPEKVEDEAVFRVLTIAEMVKCPIHFGKVYAKSSLDKIMDWQRKSSNTII 946
+LLIK G +IN D ++ AD+ +E+G I I N I + I+A G V+PGG+D T+ G + ++++ GT+AA+ GGTT +++ + SL YE ++ + C+ ++ + L N + SE L++ K V LV ++ DK ++ D E+Y+A RD + VHAEN ++A +K +L +TGPEGH LSRPE+VE EAV R +TI CP++ KV ++S+ D I ++K I
Sbjct: 2 RLLIKGGRIINDDQSFTADIYVEDGFIKQIGDNLIVPGGVKSIEANGRMVMPGGIDVHTHLQMPYLGTSTMDDFYQGTRAALAGGTTMIIDHVIPEPGCSLLGAYEQWREWADAKACCDYSLHVQLTYWNSELCSEMETLIKDKGVNSFLVYMAYKDK----YQLTDAEIYEAFTAIRDLGAIALVHAENGSIIAEEQKRILGLQITGPEGHVLSRPEEVEAEAVNRAITIGNQTNCPLYITKVMSRSAADVIALSRKKVRGQYI 262
BLAST of Dihydropyrimidinase vs. Ensembl Sea Lamprey
Match: ENSPMAT00000006054.1 (pep scaffold:Pmarinus_7.0:GL477305:540:7425:1 gene:ENSPMAG00000005460.1 transcript:ENSPMAT00000006054.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 115.931 bits (289), Expect = 2.451e-29 Identity = 65/179 (36.31%), Postives = 100/179 (55.87%), Query Frame = 2
Query: 1115 VASSHLVFDMKHKASGRNDFRCIIPGTNGVQYRMKILWDKAVKSGRMEPTSFVNCVSTTPAKLANIYPHKGTISIGSDADIIVWKGDSV----SHSNFEAGDINVFEDVICHSGPKYVIVNGIVVLDHEGNFTASKGSGQIVSPSLETMNSYFQKQLINYKLSHEVEKKIAREPYDGPV 1639
S+H F KA G++DF I GTNG++ RM I+WDK V +G+M+ FV ST AK+ N+YP KG I++GSDAD+I+W D V + ++ +A + N+FE + P VI G +V++ +G A +G G+ V P +++ +L+ + + R YDGPV
Sbjct: 7 TGSAHCTFSTAQKALGKDDFTLIPEGTNGIEERMSIVWDKGVATGKMDENQFVAVTSTNAAKVFNLYPRKGRIAVGSDADLIIWDPDVVKTISAKTHHQAVEYNIFEGMEVRGVPLAVISQGKIVME-DGTLHAMQGVGRFV-PRKAFPEQVYKRIKARSQLTE--LQGVPRGLYDGPV 181
BLAST of Dihydropyrimidinase vs. Ensembl Nematostella
Match: EDO46551 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RPQ7]) HSP 1 Score: 287.345 bits (734), Expect = 1.021e-88 Identity = 185/574 (32.23%), Postives = 303/574 (52.79%), Query Frame = 2
Query: 152 QKKLLIKCGTVINHDCTYDADVLIENGKIVNIAKN-IEDSLAECIDATGCFVLPGGVDAETNFAAKRGGIVSPENYFSGTKAAIYGGTTTVVNCLEIMKDESLKEKYEMEKDIISKEIVCNLAIQLCLPEVNEAIKSEFNELLQSKSVVPLVRLSTVDKGCHCVKIDDEELYDALCWCRDNSVLPTVHAENDKMVAILEKELLADGVTGPEGHYLSRPEKVEDEAVFRVLTIAEMVKCPIHFGKVYAKSSLDKIMDWQRKSSNTIICGTSLVA-LVHNAEKYRDPNWKVAASFVTMPALKMNKTTEFQCTELLETVASRKINHVASSHLVFDMKHKASGRNDFRCIIPGTNGVQYRMKILWDKAVKSGRMEPTSFVNCVSTTPAKLANIYPHKGTISIGSDADIIVWKGDSV----SHSNFEAGDINVFEDVICHSGPKYVIVNGIVVLDHEGNFTASKGSGQIV-SPSLETMNSYFQKQLINYKLSHEVEKKIAREPYDGPVI----DPSA---------DNKEEKHVLYSHMVNNDVYKRGGPAEDKKEALPPGQRVIRTSVKTAQPPGGSA 1813
+ ++LIK GT++N D ++ADV IENG I I+K+ I + IDA+ +LPGG+D T+ G + +++F GTKAA+ GGTT +++ + K ESL E Y+ + +++ C+ + + +E + E L++ K + + I+D E+ + C++ + VHAEN ++ K+++A G+TGPEGH + RPE+VE EA R +TIA V CP++ V +KSS I D +R ++ G + A L + Y W+ A V P L+ + +T L+ +A+ + + + F + KA G+NDFR I G NG++ RM ++W+K V +G+M+P FV STT AK+ N+YP KG I++GSDADI+VW ++ + ++ +A D N+FE + CH P I G VV + G F +GSG+ + +P S++ I+ + + KK+ REPY G V+ DP A KE + V + + D+++ G ++ +R R S + A+PPGG++
Sbjct: 8 KDRILIKGGTIVNDDQMFEADVYIENGLIKEISKSVICPGGTKVIDASRKLILPGGIDTHTHLQMPFMGTTAIDDFFIGTKAALAGGTTMIIDFVIPAKGESLLEAYDKWRGWADEKVCCDYGFHVAVTWWSEEVAEEMEILVKEKGINSFKTFMAYKD---VMMINDAEMINCYKKCKEIGAIAQVHAENGDLIDESAKKMIAMGITGPEGHEMCRPEEVEAEATQRAITIANQVSCPLYVVHVMSKSSAKVISDARRLGK--VVIGEPIAAGLGCDGTNYWHKCWRHGAGHVMGPPLRPDTSTP---EHLMNLLANDDLQCTGTDNCTFSSEQKALGKNDFRKIPNGVNGIEDRMSVIWEKGVHAGKMDPCRFVAVTSTTAAKIFNVYPQKGRIAVGSDADIVVWDPEATRVISAKTHHQAVDFNIFEGMECHGVPVVTISQGKVVYEG-GEFHVVRGSGRFIPTPPF----SHYMYSRIHTRDKNCQPKKVDREPYTGKVLTIEPDPKAAVFTSPAQRRMKEREEVKKN--PHRDLHRSGFELSGRQFD---DERPYRPSSRVAKPPGGAS 563
BLAST of Dihydropyrimidinase vs. Ensembl Nematostella
Match: EDO49158 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RH45]) HSP 1 Score: 63.1586 bits (152), Expect = 1.285e-10 Identity = 51/191 (26.70%), Postives = 83/191 (43.46%), Query Frame = 2
Query: 794 SRPEKVEDEAVFRVLTIAEMVKCPIHFGKVYAKSSLDKIMDWQRKSSNTIICGTSLVALVHNAEKYRDPNWKVAASFVTMPALKMNKTTEFQCTELLETVASRKINHVASSHLVFDMKHKASGRNDFRCIIPGTNGVQYRMKILWDKAVKSGRMEPTSFVNCVSTTPAKLANIYPHKGTISIGSDADIIVW 1366
+RPE +E++A+ V+ + + + P H + + S+LD I R S + T+ L AE+ D A + P ++ E L V R I+ V S H K + DF G + +QY + + W A G + V + P+KL ++ KG IS+G DAD ++W
Sbjct: 154 TRPESMENKAIEMVIHLCDHYRVPCHIVHLSSGSALDSIRS-ARSSGIPLTVETTHHYLSLTAEEVPDG----ATQYKCCPPIRDRSNQEV----LWNAVKFRDIDLVVSDHSPCTPDLKLLDQGDFIGAWGGISSLQYGLSLFWSGARCRG-LGLHDVVRVLCEQPSKLCSLQHRKGMISVGKDADFVIW 334
BLAST of Dihydropyrimidinase vs. Ensembl Nematostella
Match: EDO25804 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A8DVF6]) HSP 1 Score: 59.6918 bits (143), Expect = 1.629e-9 Identity = 35/111 (31.53%), Postives = 59/111 (53.15%), Query Frame = 2
Query: 161 LLIKCGTVINHDCTYDADVLIENGKIVNIAKNIEDSLAEC--IDATGCFVLPGGVDAETNFAAKRGGIVSPENYFSGTKAAIYGGTTTVV----NCLEIMKDESLKEKYEM 475
LI+ ++N ++ DVLIE+ I IA I +EC IDA G +++PG +D + +F + G+ N S ++AAI GG T+ + + E L++KY++
Sbjct: 4 FLIRNAKIVNEGVVFEGDVLIEDEFIKEIADKISPKSSECVIIDAEGSYLIPGAIDDQVHF--REPGLTHKGNIASESRAAIAGGITSFIEQPNTVPNAVTQELLEQKYQI 112
BLAST of Dihydropyrimidinase vs. Ensembl Medaka
Match: crmp1 (dihydropyrimidinase-related protein 1 [Source:NCBI gene;Acc:101159888]) HSP 1 Score: 305.449 bits (781), Expect = 2.814e-95 Identity = 180/506 (35.57%), Postives = 275/506 (54.35%), Query Frame = 2
Query: 149 TQKKLLIKCGTVINHDCTYDADVLIENGKIVNIAKN-IEDSLAECIDATGCFVLPGGVDAETNFAAKRGGIVSPENYFSGTKAAIYGGTTTVVNCLEIMKDESLKEKYEMEKDIISKEIVCNLAIQLCLPEVNEAIKSEFNELLQSKSVVPL-VRLSTVDKGCHCVKIDDEELYDALCWCRDNSVLPTVHAENDKMVAILEKELLADGVTGPEGHYLSRPEKVEDEAVFRVLTIAEMVKCPIHFGKVYAKSSLDKIMDWQRKSSNTIICGTSLVA-LVHNAEKYRDPNWKVAASFVTMPALKMNKTTEFQCTELLETVASRKINHVASSHLVFDMKHKASGRNDFRCIIPGTNGVQYRMKILWDKAVKSGRMEPTSFVNCVSTTPAKLANIYPHKGTISIGSDADIIVWKGDSV----SHSNFEAGDINVFEDVICHSGPKYVIVNGIVVLDHEGNFTASKGSGQIVSPSLETMNSYFQKQLINYKLSHEVEKKIAREPYDGPVID 1645
T ++LLI+ G V+N D ++ DV IE+G I + +N + + I+A G V+PGG+D T G +++ GTKAA+ GGTT +++ + ESL E +E ++ K C+ ++ + +P NE +K E L+Q K + V ++ D ++ D +LY+A + + + VHAEN ++ ++++L G+TGPEGH LSRPE+VE EAVFR +T+ V CP++ KV +KS+ D I +RK S ++ G + A L + Y NW AA++VT P L + TT LL AS + V SSH + KA G++DF I GTNGV+ RM +WDKAV G+M+ FV ST AK+ N+YP KG I++ SDADI++W D V + A + N+FE + C GP V+ G VV + G +G+G+ + P + FQ+ I ++ ++ + R YDGPV D
Sbjct: 16 TDERLLIRGGRVVNDDRSFFGDVYIEDGLIKQVGENLVVPGGVKVIEANGRMVIPGGIDVNTCLMKTYLGTQPVDDFLQGTKAALAGGTTMIIDHVTPEPGESLLEAFERWQEAADKRACCDYSLHVDIPLWNETVKDELEVLVQDKGINSFQVYMAYKD----VYQMTDSQLYEAFSFLKQLGAVVLVHAENGDLIFEEQRKILGMGITGPEGHPLSRPEEVEAEAVFRAITLGNCVNCPVYITKVMSKSAADTIAQARRKGS--VVFGEPITAGLATDGSHYWSKNWAKAAAYVTSPPLSPDPTTPEHLHTLL---ASGDLQVVGSSHCAYSTSQKAIGKDDFTLIPEGTNGVEERMGFVWDKAVAMGKMDENQFVAVTSTNAAKIFNLYPRKGRIAVDSDADIVIWDPDIVKTITAKQQQSAAEYNIFEGLECRGGPALVLSQGRVVYEG-GKLQIQQGTGRFI-PRKPFPDYAFQR--IKFRNQVSSKQGVTRGVYDGPVHD 508
BLAST of Dihydropyrimidinase vs. Ensembl Medaka
Match: crmp1 (dihydropyrimidinase-related protein 1 [Source:NCBI gene;Acc:101159888]) HSP 1 Score: 303.523 bits (776), Expect = 1.567e-93 Identity = 179/504 (35.52%), Postives = 274/504 (54.37%), Query Frame = 2
Query: 155 KKLLIKCGTVINHDCTYDADVLIENGKIVNIAKN-IEDSLAECIDATGCFVLPGGVDAETNFAAKRGGIVSPENYFSGTKAAIYGGTTTVVNCLEIMKDESLKEKYEMEKDIISKEIVCNLAIQLCLPEVNEAIKSEFNELLQSKSVVPL-VRLSTVDKGCHCVKIDDEELYDALCWCRDNSVLPTVHAENDKMVAILEKELLADGVTGPEGHYLSRPEKVEDEAVFRVLTIAEMVKCPIHFGKVYAKSSLDKIMDWQRKSSNTIICGTSLVA-LVHNAEKYRDPNWKVAASFVTMPALKMNKTTEFQCTELLETVASRKINHVASSHLVFDMKHKASGRNDFRCIIPGTNGVQYRMKILWDKAVKSGRMEPTSFVNCVSTTPAKLANIYPHKGTISIGSDADIIVWKGDSV----SHSNFEAGDINVFEDVICHSGPKYVIVNGIVVLDHEGNFTASKGSGQIVSPSLETMNSYFQKQLINYKLSHEVEKKIAREPYDGPVID 1645
++LLI+ G V+N D ++ DV IE+G I + +N + + I+A G V+PGG+D T G +++ GTKAA+ GGTT +++ + ESL E +E ++ K C+ ++ + +P NE +K E L+Q K + V ++ D ++ D +LY+A + + + VHAEN ++ ++++L G+TGPEGH LSRPE+VE EAVFR +T+ V CP++ KV +KS+ D I +RK S ++ G + A L + Y NW AA++VT P L + TT LL AS + V SSH + KA G++DF I GTNGV+ RM +WDKAV G+M+ FV ST AK+ N+YP KG I++ SDADI++W D V + A + N+FE + C GP V+ G VV + G +G+G+ + P + FQ+ I ++ ++ + R YDGPV D
Sbjct: 121 ERLLIRGGRVVNDDRSFFGDVYIEDGLIKQVGENLVVPGGVKVIEANGRMVIPGGIDVNTCLMKTYLGTQPVDDFLQGTKAALAGGTTMIIDHVTPEPGESLLEAFERWQEAADKRACCDYSLHVDIPLWNETVKDELEVLVQDKGINSFQVYMAYKD----VYQMTDSQLYEAFSFLKQLGAVVLVHAENGDLIFEEQRKILGMGITGPEGHPLSRPEEVEAEAVFRAITLGNCVNCPVYITKVMSKSAADTIAQARRKGS--VVFGEPITAGLATDGSHYWSKNWAKAAAYVTSPPLSPDPTTPEHLHTLL---ASGDLQVVGSSHCAYSTSQKAIGKDDFTLIPEGTNGVEERMGFVWDKAVAMGKMDENQFVAVTSTNAAKIFNLYPRKGRIAVDSDADIVIWDPDIVKTITAKQQQSAAEYNIFEGLECRGGPALVLSQGRVVYEG-GKLQIQQGTGRFI-PRKPFPDYAFQR--IKFRNQVSSKQGVTRGVYDGPVHD 611
BLAST of Dihydropyrimidinase vs. Ensembl Medaka
Match: dpysl3 (dihydropyrimidinase-related protein 3 [Source:NCBI gene;Acc:101165934]) HSP 1 Score: 297.36 bits (760), Expect = 3.640e-91 Identity = 186/573 (32.46%), Postives = 300/573 (52.36%), Query Frame = 2
Query: 146 ETQKKLLIKCGTVINHDCTYDADVLIENGKIVNIAKN-IEDSLAECIDATGCFVLPGGVDAETNFAAKRGGIVSPENYFSGTKAAIYGGTTTVVNCLEIMKDESLKEKYEMEKDIISKEIVCNLAIQLCLPEVNEAIKSEFNELLQSKSVVPL-VRLSTVDKGCHCVKIDDEELYDALCWCRDNSVLPTVHAENDKMVAILEKELLADGVTGPEGHYLSRPEKVEDEAVFRVLTIAEMVKCPIHFGKVYAKSSLDKIMDWQRKSSNTIICGTSLVALVHNAEKYRDPNWKVAASFVTMPALKMNKTTEFQCTELLETVASRKINHVASSHLVFDMKHKASGRNDFRCIIPGTNGVQYRMKILWDKAVKSGRMEPTSFVNCVSTTPAKLANIYPHKGTISIGSDADIIVWKGDSV----SHSNFEAGDINVFEDVICHSGPKYVIVNGIVVLDHEGNFTASKGSGQIV--SPSLETMNSYFQKQLINYKLSHEVEKKIAREPYDGPVID--------PSADNKEEKHVLYSHMVNNDVYK-RGGPAEDKKEALPPGQRVIRTSVKTAQPPGGSA 1813
E +LLIK G ++N D ++ AD+ +E+G I I N I + I+A G V+PGG+D T+F G + +++ G+KAA+ GGTT +V+ + SL E Y+ + ++ C+ ++ + + N+++K E + L++ K V V ++ D ++ + +LY+ + + + VHAEN +++A + +L G+TGPEGH LSRPE++E EAVFR +TIA CP++ +V +KS+ D I+ RK N + +L + Y NW AA+FVT P L + TT LL AS ++ S+H F + KA G++DF I G NGV+ RM ++WDKAV +G+M+ FV ST AK+ N+YP KG I++GSDAD+I+W DSV + ++ A + N+FE + P VI G +VL+ +G + G+G+ + SP + F + + + V + + R YDGPV + PSA + ++ + G P D+ P G+R++ PPGG +
Sbjct: 96 EKSDRLLIKGGRIVNDDQSFHADIYMEDGLIKQIGDNLIVPGGVKTIEANGKMVIPGGIDIHTHFQMPYRGTTTVDDFAQGSKAALAGGTTMIVDHVIPEPGTSLMEAYDQWRQWADEKACCDYSLHVDITHWNDSVKQEVDSLIKDKGVNSFQVYMAYKD----YYQLSNSQLYEIFTFLAEKGGIVQVHAENGEIIAEEQARMLQMGITGPEGHVLSRPEELEAEAVFRAVTIASQTNCPLYVTRVMSKSAAD-IISQARKKGNVVFGEPITASLGTDGTHYWSKNWAKAAAFVTSPPLSPDPTTPDYLNTLL---ASGDLSVTGSAHCTFSVAQKAIGKDDFTQIPEGVNGVEERMALIWDKAVTTGKMDENMFVAITSTNAAKILNLYPRKGRIAVGSDADLIIWDTDSVRTITAKTHNSAAEYNIFEGMELRGAPLVVICQGKIVLE-DGKLQVTSGAGRFIPCSPFPD-----FAYKRVKARKQLAVLRAVPRGMYDGPVSEFSMSRGGTPSASARTSPTKQPVRNLHQSGFSLTGPPTPDEVPIRPAGRRIV-------VPPGGRS 647
BLAST of Dihydropyrimidinase vs. Ensembl Medaka
Match: dpysl3 (dihydropyrimidinase-related protein 3 [Source:NCBI gene;Acc:101165934]) HSP 1 Score: 294.278 bits (752), Expect = 9.547e-91 Identity = 173/505 (34.26%), Postives = 277/505 (54.85%), Query Frame = 2
Query: 149 TQKKLLIKCGTVINHDCTYDADVLIENGKIVNIAKN-IEDSLAECIDATGCFVLPGGVDAETNFAAKRGGIVSPENYFSGTKAAIYGGTTTVVNCLEIMKDESLKEKYEMEKDIISKEIVCNLAIQLCLPEVNEAIKSEFNELLQSKSVVPL-VRLSTVDKGCHCVKIDDEELYDALCWCRDNSVLPTVHAENDKMVAILEKELLADGVTGPEGHYLSRPEKVEDEAVFRVLTIAEMVKCPIHFGKVYAKSSLDKIMDWQRKSSNTIICGTSLVALVHNAEKYRDPNWKVAASFVTMPALKMNKTTEFQCTELLETVASRKINHVASSHLVFDMKHKASGRNDFRCIIPGTNGVQYRMKILWDKAVKSGRMEPTSFVNCVSTTPAKLANIYPHKGTISIGSDADIIVWKGDSV----SHSNFEAGDINVFEDVICHSGPKYVIVNGIVVLDHEGNFTASKGSGQIV--SPSLETMNSYFQKQLINYKLSHEVEKKIAREPYDGPV 1639
T +LLIK G ++N D ++ AD+ +E+G I I N I + I+A G V+PGG+D T+F G + +++ G+KAA+ GGTT +V+ + SL E Y+ + ++ C+ ++ + + N+++K E + L++ K V V ++ D ++ + +LY+ + + + VHAEN +++A + +L G+TGPEGH LSRPE++E EAVFR +TIA CP++ +V +KS+ D I+ RK N + +L + Y NW AA+FVT P L + TT LL AS ++ S+H F + KA G++DF I G NGV+ RM ++WDKAV +G+M+ FV ST AK+ N+YP KG I++GSDAD+I+W DSV + ++ A + N+FE + P VI G +VL+ +G + G+G+ + SP + F + + + V + + R YDGPV
Sbjct: 13 TSDRLLIKGGRIVNDDQSFHADIYMEDGLIKQIGDNLIVPGGVKTIEANGKMVIPGGIDIHTHFQMPYRGTTTVDDFAQGSKAALAGGTTMIVDHVIPEPGTSLMEAYDQWRQWADEKACCDYSLHVDITHWNDSVKQEVDSLIKDKGVNSFQVYMAYKD----YYQLSNSQLYEIFTFLAEKGGIVQVHAENGEIIAEEQARMLQMGITGPEGHVLSRPEELEAEAVFRAVTIASQTNCPLYVTRVMSKSAAD-IISQARKKGNVVFGEPITASLGTDGTHYWSKNWAKAAAFVTSPPLSPDPTTPDYLNTLL---ASGDLSVTGSAHCTFSVAQKAIGKDDFTQIPEGVNGVEERMALIWDKAVTTGKMDENMFVAITSTNAAKILNLYPRKGRIAVGSDADLIIWDTDSVRTITAKTHNSAAEYNIFEGMELRGAPLVVICQGKIVLE-DGKLQVTSGAGRFIPCSPFPD-----FAYKRVKARKQLAVLRAVPRGMYDGPV 503
BLAST of Dihydropyrimidinase vs. Ensembl Medaka
Match: crmp1 (dihydropyrimidinase-related protein 1 [Source:NCBI gene;Acc:101159888]) HSP 1 Score: 288.5 bits (737), Expect = 4.681e-89 Identity = 188/566 (33.22%), Postives = 285/566 (50.35%), Query Frame = 2
Query: 200 TYDADVLIENGKIVNIAKN-IEDSLAECIDATGCFVLPGGVDAETNFAAKRGGIVSPENYFSGTKAAIYGGTTTVVNCLEIMKDESLKEKYEMEKDIISKEIVCNLAIQLCLPEVNEAIKSEFNELLQSKSVVPL-VRLSTVDKGCHCVKIDDEELYDALCWCRDNSVLPTVHAENDKMVAILEKELLADGVTGPEGHYLSRPEKVEDEAVFRVLTIAEMVKCPIHFGKVYAKSSLDKIMDWQRKSSNTIICGTSLVA-LVHNAEKYRDPNWKVAASFVTMPALKMNKTTEFQCTELLETVASRKINHVASSHLVFDMKHKASGRNDFRCIIPGTNGVQYRMKILWDKAVKSGRMEPTSFVNCVSTTPAKLANIYPHKGTISIGSDADIIVWKGDSV----SHSNFEAGDINVFEDVICHSGPKYVIVNGIVVLDHEGNFTASKGSGQIVSPSLETMNSYFQKQLINYKLSHEVEKKIAREPYDGPVID-----------PSADNKEEKH----VLYSHMVNNDVYKRGGPAEDKKEALPPGQRVIRTSVKTAQPPGGSAQASWWG 1831
++ DV IE+G I + +N + + I+A G V+PGG+D T G +++ GTKAA+ GGTT +++ + ESL E +E ++ K C+ ++ + +P NE +K E L+Q K + V ++ D ++ D +LY+A + + + VHAEN ++ ++++L G+TGPEGH LSRPE+VE EAVFR +T+ V CP++ KV +KS+ D I +RK S ++ G + A L + Y NW AA++VT P L + TT LL AS + V SSH + KA G++DF I GTNGV+ RM +WDKAV G+M+ FV ST AK+ N+YP KG I++ SDADI++W D V + A + N+FE + C GP V+ G VV + G +G+G+ + P + FQ+ I ++ ++ + R YDGPV D PSA H V H+ N + G D G R++ PPGG + + G
Sbjct: 2 SFFGDVYIEDGLIKQVGENLVVPGGVKVIEANGRMVIPGGIDVNTCLMKTYLGTQPVDDFLQGTKAALAGGTTMIIDHVTPEPGESLLEAFERWQEAADKRACCDYSLHVDIPLWNETVKDELEVLVQDKGINSFQVYMAYKD----VYQMTDSQLYEAFSFLKQLGAVVLVHAENGDLIFEEQRKILGMGITGPEGHPLSRPEEVEAEAVFRAITLGNCVNCPVYITKVMSKSAADTIAQARRKGS--VVFGEPITAGLATDGSHYWSKNWAKAAAYVTSPPLSPDPTTPEHLHTLL---ASGDLQVVGSSHCAYSTSQKAIGKDDFTLIPEGTNGVEERMGFVWDKAVAMGKMDENQFVAVTSTNAAKIFNLYPRKGRIAVDSDADIVIWDPDIVKTITAKQQQSAAEYNIFEGLECRGGPALVLSQGRVVYEG-GKLQIQQGTGRFI-PRKPFPDYAFQR--IKFRNQVSSKQGVTRGVYDGPVHDVTPTPKYITPSPSAKTSPTSHQPPTVRNLHLSN---FSLSGAQIDDNIPRRSGHRIV-------APPGGRSNITSLG 544
BLAST of Dihydropyrimidinase vs. Planmine SMEST
Match: SMESG000060188.1 (SMESG000060188.1) HSP 1 Score: 1164.83 bits (3012), Expect = 0.000e+0 Identity = 562/564 (99.65%), Postives = 563/564 (99.82%), Query Frame = 2
Query: 140 MSETQKKLLIKCGTVINHDCTYDADVLIENGKIVNIAKNIEDSLAECIDATGCFVLPGGVDAETNFAAKRGGIVSPENYFSGTKAAIYGGTTTVVNCLEIMKDESLKEKYEMEKDIISKEIVCNLAIQLCLPEVNEAIKSEFNELLQSKSVVPLVRLSTVDKGCHCVKIDDEELYDALCWCRDNSVLPTVHAENDKMVAILEKELLADGVTGPEGHYLSRPEKVEDEAVFRVLTIAEMVKCPIHFGKVYAKSSLDKIMDWQRKSSNTIICGTSLVALVHNAEKYRDPNWKVAASFVTMPALKMNKTTEFQCTELLETVASRKINHVASSHLVFDMKHKASGRNDFRCIIPGTNGVQYRMKILWDKAVKSGRMEPTSFVNCVSTTPAKLANIYPHKGTISIGSDADIIVWKGDSVSHSNFEAGDINVFEDVICHSGPKYVIVNGIVVLDHEGNFTASKGSGQIVSPSLETMNSYFQKQLINYKLSHEVEKKIAREPYDGPVIDPSADNKEEKHVLYSHMVNNDVYKRGGPAEDKKEALPPGQRVIRTSVKTAQPPGGSAQASWWG 1831
MSETQKKLLIKCGTVINHDCTYDADVLIENGKIVNIAKNIEDSLAECIDATGCFVLPGGVDAETNFAAKRGGIVSPENYFSGTKAAIYGGTTTVVNCLEIMKDESLKEKYEMEKDIISKEIVCNLAIQLCLPEVNEAIKSEFNELLQSKSVVPLVRLSTVDKGCHCVKIDDEELYDALCWCRDNSVLPTVHAENDKMVAILEKELLADGVTGPEGHYLSRPEKVEDEAVFRVLTIAEMVKCPIHFGKVYAKSSLDKIMDWQRKSSNTIICGTSLVALVHNAEKYRDPNWKVAASFVTMPALKMNK TEFQCTELLETVASRKINHVASSHLVFDMKHKASGRNDFRCIIPGTNGVQYRMKILWDKAVKSGRMEPTSFVNCVSTTPAKLANIYPHKGTISIGSDADIIVWKGDSVSHSNFEAGDINVFEDVICHSGPKYVIVNGIVVLDHEGNFTASKGSGQIVSPSLETMNSYFQKQLINYKLS+EVEKKIAREPYDGPVIDPSADNKEEKHVLYSHMVNNDVYKRGGPAEDKKEALPPGQRVIRTSVKTAQPPGGSAQASWWG
Sbjct: 1 MSETQKKLLIKCGTVINHDCTYDADVLIENGKIVNIAKNIEDSLAECIDATGCFVLPGGVDAETNFAAKRGGIVSPENYFSGTKAAIYGGTTTVVNCLEIMKDESLKEKYEMEKDIISKEIVCNLAIQLCLPEVNEAIKSEFNELLQSKSVVPLVRLSTVDKGCHCVKIDDEELYDALCWCRDNSVLPTVHAENDKMVAILEKELLADGVTGPEGHYLSRPEKVEDEAVFRVLTIAEMVKCPIHFGKVYAKSSLDKIMDWQRKSSNTIICGTSLVALVHNAEKYRDPNWKVAASFVTMPALKMNKNTEFQCTELLETVASRKINHVASSHLVFDMKHKASGRNDFRCIIPGTNGVQYRMKILWDKAVKSGRMEPTSFVNCVSTTPAKLANIYPHKGTISIGSDADIIVWKGDSVSHSNFEAGDINVFEDVICHSGPKYVIVNGIVVLDHEGNFTASKGSGQIVSPSLETMNSYFQKQLINYKLSNEVEKKIAREPYDGPVIDPSADNKEEKHVLYSHMVNNDVYKRGGPAEDKKEALPPGQRVIRTSVKTAQPPGGSAQASWWG 564
BLAST of Dihydropyrimidinase vs. Planmine SMEST
Match: SMESG000060188.1 (SMESG000060188.1) HSP 1 Score: 1160.21 bits (3000), Expect = 0.000e+0 Identity = 560/564 (99.29%), Postives = 562/564 (99.65%), Query Frame = 2
Query: 140 MSETQKKLLIKCGTVINHDCTYDADVLIENGKIVNIAKNIEDSLAECIDATGCFVLPGGVDAETNFAAKRGGIVSPENYFSGTKAAIYGGTTTVVNCLEIMKDESLKEKYEMEKDIISKEIVCNLAIQLCLPEVNEAIKSEFNELLQSKSVVPLVRLSTVDKGCHCVKIDDEELYDALCWCRDNSVLPTVHAENDKMVAILEKELLADGVTGPEGHYLSRPEKVEDEAVFRVLTIAEMVKCPIHFGKVYAKSSLDKIMDWQRKSSNTIICGTSLVALVHNAEKYRDPNWKVAASFVTMPALKMNKTTEFQCTELLETVASRKINHVASSHLVFDMKHKASGRNDFRCIIPGTNGVQYRMKILWDKAVKSGRMEPTSFVNCVSTTPAKLANIYPHKGTISIGSDADIIVWKGDSVSHSNFEAGDINVFEDVICHSGPKYVIVNGIVVLDHEGNFTASKGSGQIVSPSLETMNSYFQKQLINYKLSHEVEKKIAREPYDGPVIDPSADNKEEKHVLYSHMVNNDVYKRGGPAEDKKEALPPGQRVIRTSVKTAQPPGGSAQASWWG 1831
+S TQKKLLIKCGTVINHDCTYDADVLIENGKIVNIAKNIEDSLAECIDATGCFVLPGGVDAETNFAAKRGGIVSPENYFSGTKAAIYGGTTTVVNCLEIMKDESLKEKYEMEKDIISKEIVCNLAIQLCLPEVNEAIKSEFNELLQSKSVVPLVRLSTVDKGCHCVKIDDEELYDALCWCRDNSVLPTVHAENDKMVAILEKELLADGVTGPEGHYLSRPEKVEDEAVFRVLTIAEMVKCPIHFGKVYAKSSLDKIMDWQRKSSNTIICGTSLVALVHNAEKYRDPNWKVAASFVTMPALKMNK TEFQCTELLETVASRKINHVASSHLVFDMKHKASGRNDFRCIIPGTNGVQYRMKILWDKAVKSGRMEPTSFVNCVSTTPAKLANIYPHKGTISIGSDADIIVWKGDSVSHSNFEAGDINVFEDVICHSGPKYVIVNGIVVLDHEGNFTASKGSGQIVSPSLETMNSYFQKQLINYKLS+EVEKKIAREPYDGPVIDPSADNKEEKHVLYSHMVNNDVYKRGGPAEDKKEALPPGQRVIRTSVKTAQPPGGSAQASWWG
Sbjct: 4 VSLTQKKLLIKCGTVINHDCTYDADVLIENGKIVNIAKNIEDSLAECIDATGCFVLPGGVDAETNFAAKRGGIVSPENYFSGTKAAIYGGTTTVVNCLEIMKDESLKEKYEMEKDIISKEIVCNLAIQLCLPEVNEAIKSEFNELLQSKSVVPLVRLSTVDKGCHCVKIDDEELYDALCWCRDNSVLPTVHAENDKMVAILEKELLADGVTGPEGHYLSRPEKVEDEAVFRVLTIAEMVKCPIHFGKVYAKSSLDKIMDWQRKSSNTIICGTSLVALVHNAEKYRDPNWKVAASFVTMPALKMNKNTEFQCTELLETVASRKINHVASSHLVFDMKHKASGRNDFRCIIPGTNGVQYRMKILWDKAVKSGRMEPTSFVNCVSTTPAKLANIYPHKGTISIGSDADIIVWKGDSVSHSNFEAGDINVFEDVICHSGPKYVIVNGIVVLDHEGNFTASKGSGQIVSPSLETMNSYFQKQLINYKLSNEVEKKIAREPYDGPVIDPSADNKEEKHVLYSHMVNNDVYKRGGPAEDKKEALPPGQRVIRTSVKTAQPPGGSAQASWWG 567
BLAST of Dihydropyrimidinase vs. Planmine SMEST
Match: SMESG000002633.1 (SMESG000002633.1) HSP 1 Score: 321.242 bits (822), Expect = 4.797e-101 Identity = 192/589 (32.60%), Postives = 314/589 (53.31%), Query Frame = 2
Query: 134 LFMSETQKKLLIKCGTVINHDCTYDADVLIENGKIVNIAKNIE-DSLAECIDATGCFVLPGGVDAETNFAAKRGGIVSPENYFSGTKAAIYGGTTTVVNCLEIMKDESLKEKYEMEKDIISKEIVCNLAIQLCLPEVNEAIKSEFNELLQSKSVVPL-VRLSTVDKGCHCVKIDDEELYDALCWCRDNSVLPTVHAENDKMVAILEKELLADGVTGPEGHYLSRPEKVEDEAVFRVLTIAEMVKCPIHFGKVYAKSSLDKIMDWQRKSSNTIICGTSLVA-LVHNAEKYRDPNWKVAASFVTMPALKMNKTTEFQCTELLETVASRKINHVASSHLVFDMKHKASGRNDFRCIIPGTNGVQYRMKILWDKAVKSGRMEPTSFVNCVSTTPAKLANIYPHKGTISIGSDADIIVWKGD---SVSHS-NFEAGDINVFEDVICHSGPKYVIVNGIVVLDHEGNFTASKGSGQIVSPSLETMNSYFQKQLINYKLSHEVEKKIAREPYDGPVIDPSA-----------DNKEEKHVLYSHMVNND--VYKRGGP-AEDKKEALPPGQ----RVIRTSVKTAQPPGGSAQASW 1825
L + +Q +L IK ++N D +DADV IE+G I + N+ C++A G ++PGG+D T+ G VS ++++SGT+AA+ GGTT +++ + K SL + Y ++ ++ C+ + + + NE++ +E +L + + ++ D + ++D+E+Y+ C+ L VHAEN K++ EL++ G+TGPEGH SRPE+VE EA R + +A+ CP++ V +K + D I D +R+ ++ G + A L + Y W+ AA +V P L+ ++ T L++ +AS + + H VF KA G++DFR I G NGV+ RM ++W+K V +G ++P FV ST AK+ NIYP KG I IGSDAD+++W D ++S S +++ D N+FE + CH + VI G VVL+ +GN ++G+G+ V P+ N F K + + + K+ R+PYDGPV D S D +++ + S VN + GG +D AL Q R+ ++T QPPGG+A + W
Sbjct: 15 LHLQSSQNRLCIKGAKIVNDDRMFDADVYIEDGIIKQLGTNLVIPGGVRCVEANGKLLIPGGIDTHTHMEFPFMGTVSSDDFYSGTRAALAGGTTMIIDFVIGQKGTSLIDSYNQYREKADSKVCCDYGLHVIVSSYNESVGNEMEKLASEHGINSFKIFMAYKDS----LMLEDDEMYEVFKKCKSIGALAQVHAENGKLIEKKSLELISKGITGPEGHLYSRPEEVECEATNRAIMLADQANCPLYVVHVMSKGAADIISDARRQGK--VVFGEPIAAGLGTDGSHYSHSCWRHAAGYVMSPPLRNDRNTS---KHLMQLLASGDLECTGTDHCVFKASQKALGKDDFRSIPNGVNGVEDRMSVIWEKGVVTGILDPCKFVAVTSTNAAKIFNIYPKKGRIDIGSDADLVLWNPDVRRTISASTHYQNVDFNIFEGMHCHGVAEMVISGGKVVLE-DGNLRVAQGTGKFV-PTNPFCNYVFNKVKLRDQCHKTLANKVERQPYDGPVEDLSKEMTNLNMNFDDDTDSQQNAISSEFVNTKRPLTSGGGRHMQDSSFALSGAQIDDNLPTRSGIRTRQPPGGTATSLW 592
BLAST of Dihydropyrimidinase vs. Planmine SMEST
Match: SMESG000028784.1 (SMESG000028784.1) HSP 1 Score: 186.808 bits (473), Expect = 3.613e-51 Identity = 133/451 (29.49%), Postives = 226/451 (50.11%), Query Frame = 2
Query: 158 KLLIKCGTVINHDCTYDADVLIENGKIVNIAKNIEDSL-AECIDATGCFVLPGGVDAETNFAAKRGGIVSPEN---YFSGTKAAIYGGTTTVVNCLEIMKDESLKEKYEMEKDIISKEIVCNLAIQLCL-PEVNEAIKSEFNELLQSKSVVPLVRLSTVDKGCHCVKIDDE---ELYDALCWCRDNSVLPTVHAENDKMVAILEKELLADGVTGPEGHYLSRPEKVEDEAVFRVLTIAEMVKCPIHFGKVYAKSSLDKIMDWQRKSSNTIICGTSLVALVHNAEKYRDPNWKVAASFVTMPALKMNKTTEFQCTELLETVASRKINHVASSHLVFDMKHKASGRNDFRCIIPGTNGVQYRMKILWDKAVKSGRMEPTSFVNCVSTTPAKLANIYPHKGTISIGSDADIIVW---KGDSVSH-SNFEAGDINVFEDVICHSGPKYVIVNGIV 1474
K+L+K G ++N D + +DVLIEN I I ++I S + ID T ++PGG+D TNF +SP + + + AA+ GGTTT++ ++ L + + + +++CN + + P +E +KS + L R ++ C + I +E L C++ L + + + +E+EL+ G++GPEG + SR + E E ++R+L + + C + +V + K++ + I T AL ++ KY NW +AS +T P ++ + Q ++ ++ I+ VAS H ++ G+ DFR I G +GV+ R+ +LWD+ VKSG + FV+ ST AK+ N+YP +G I++GS ADI++W K ++S S D N+FE + C P+ VIVNG V
Sbjct: 2 KMLLKGGYIVNSDRKFQSDVLIENNIIKQIGQSIVVSGDTKVIDVTNKLIIPGGIDPSTNFN------LSPNHRDILHNESMAALAGGTTTIITLVKEQSGAELVNSLKALQSDLKSKVLCNYGFCVQIDPNDDECVKS----------MEKLARQFGIN--CFQMTIGNEINANTVSVLKKCKELQCLLKLRVHDSTYLEAVEEELITAGISGPEGFFQSRCIENEMEQLYRILKLNHVFPCCLIIPQVM-NEDIAKLVAKMKMEGRPIFSETIPPALALSSHKYFSNNWDESASLITDPPVRND-----QDAAIIRSIHCGDIDMVASEHTTITNADRSIGKRDFRNIPHGVSGVEERLSMLWDRGVKSGIINECEFVSATSTNAAKIFNLYPDRGHIAVGSVADIVIWNPVKTRTISALSQHLQNDTNIFEGISCQGVPEVVIVNGSV 428
BLAST of Dihydropyrimidinase vs. Planmine SMEST
Match: SMESG000028784.1 (SMESG000028784.1) HSP 1 Score: 184.882 bits (468), Expect = 1.489e-50 Identity = 132/450 (29.33%), Postives = 225/450 (50.00%), Query Frame = 2
Query: 161 LLIKCGTVINHDCTYDADVLIENGKIVNIAKNIEDSL-AECIDATGCFVLPGGVDAETNFAAKRGGIVSPEN---YFSGTKAAIYGGTTTVVNCLEIMKDESLKEKYEMEKDIISKEIVCNLAIQLCL-PEVNEAIKSEFNELLQSKSVVPLVRLSTVDKGCHCVKIDDE---ELYDALCWCRDNSVLPTVHAENDKMVAILEKELLADGVTGPEGHYLSRPEKVEDEAVFRVLTIAEMVKCPIHFGKVYAKSSLDKIMDWQRKSSNTIICGTSLVALVHNAEKYRDPNWKVAASFVTMPALKMNKTTEFQCTELLETVASRKINHVASSHLVFDMKHKASGRNDFRCIIPGTNGVQYRMKILWDKAVKSGRMEPTSFVNCVSTTPAKLANIYPHKGTISIGSDADIIVW---KGDSVSH-SNFEAGDINVFEDVICHSGPKYVIVNGIV 1474
+L+K G ++N D + +DVLIEN I I ++I S + ID T ++PGG+D TNF +SP + + + AA+ GGTTT++ ++ L + + + +++CN + + P +E +KS + L R ++ C + I +E L C++ L + + + +E+EL+ G++GPEG + SR + E E ++R+L + + C + +V + K++ + I T AL ++ KY NW +AS +T P ++ + Q ++ ++ I+ VAS H ++ G+ DFR I G +GV+ R+ +LWD+ VKSG + FV+ ST AK+ N+YP +G I++GS ADI++W K ++S S D N+FE + C P+ VIVNG V
Sbjct: 1 MLLKGGYIVNSDRKFQSDVLIENNIIKQIGQSIVVSGDTKVIDVTNKLIIPGGIDPSTNFN------LSPNHRDILHNESMAALAGGTTTIITLVKEQSGAELVNSLKALQSDLKSKVLCNYGFCVQIDPNDDECVKS----------MEKLARQFGIN--CFQMTIGNEINANTVSVLKKCKELQCLLKLRVHDSTYLEAVEEELITAGISGPEGFFQSRCIENEMEQLYRILKLNHVFPCCLIIPQVM-NEDIAKLVAKMKMEGRPIFSETIPPALALSSHKYFSNNWDESASLITDPPVRND-----QDAAIIRSIHCGDIDMVASEHTTITNADRSIGKRDFRNIPHGVSGVEERLSMLWDRGVKSGIINECEFVSATSTNAAKIFNLYPDRGHIAVGSVADIVIWNPVKTRTISALSQHLQNDTNIFEGISCQGVPEVVIVNGSV 426 The following BLAST results are available for this feature:
BLAST of Dihydropyrimidinase vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99) Total hits: 5
BLAST of Dihydropyrimidinase vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99) Total hits: 5
BLAST of Dihydropyrimidinase vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99) Total hits: 3
BLAST of Dihydropyrimidinase vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99) Total hits: 5
BLAST of Dihydropyrimidinase vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99) Total hits: 5
BLAST of Dihydropyrimidinase vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99) Total hits: 5
BLAST of Dihydropyrimidinase vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt) Total hits: 5
BLAST of Dihydropyrimidinase vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL) Total hits: 5
BLAST of Dihydropyrimidinase vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99) Total hits: 5
BLAST of Dihydropyrimidinase vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99) Total hits: 3
BLAST of Dihydropyrimidinase vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46) Total hits: 0
BLAST of Dihydropyrimidinase vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46) Total hits: 3
BLAST of Dihydropyrimidinase vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99) Total hits: 5
BLAST of Dihydropyrimidinase vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST) Total hits: 5
Analyses
This transcript is derived from or has results from the following analyses Sequences
The following sequences are available for this feature:
transcript sequence >SMED30013480 ID=SMED30013480|Name=Dihydropyrimidinase|organism=Schmidtea mediterranea sexual|type=transcript|length=1993bpback to top protein sequence of SMED30013480-orf-1 >SMED30013480-orf-1 ID=SMED30013480-orf-1|Name=SMED30013480-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=565bp MSETQKKLLIKCGTVINHDCTYDADVLIENGKIVNIAKNIEDSLAECIDAback to top Annotated Terms
The following terms have been associated with this transcript:
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
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