Nuclear transcription factor Y subunit alpha

Overview


Name	Nuclear transcription factor Y subunit alpha
Smed ID	SMED30013473
Length (bp)	1078

Neoblast Clusters

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Overview

Single cell RNA-seq of pluripotent neoblasts and its early progenies

We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)

Explore this single cell expression dataset with our NB Cluster Shiny App

Neoblast Population

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.

Expression of Nuclear transcription factor Y subunit alpha (SMED30013473) t-SNE clustered cells

Violin plots show distribution of expression levels for Nuclear transcription factor Y subunit alpha (SMED30013473) in cells (dots) of each of the 12 neoblast clusters.

Sub-lethal Irradiated Surviving X1 and X2 Cell Population

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of Nuclear transcription factor Y subunit alpha (SMED30013473) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

Anatomical Expression

PAGE et. al., 2020

SMED30013473

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE

PAGE Curations: 4

Expressed In	Reference Transcript	Gene Models	Published Transcript	Transcriptome	Publication
testis	SMED30013473	SMESG000010136.1	KU366702	smed_ncbi_20200123	PMID:27304889 Iyer et al., 2016
nervous system	SMED30013473	SMESG000010136.1	dd_Smed_v4_8585_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
head region	SMED30013473	SMESG000010136.1	dd_Smed_v6_8585_0_1	dd_Smed_v6	PMID:28171748 Stückemann et al., 2017
head region	SMED30013473	SMESG000010136.1	OX_Smed_1.0.16275	ox_Smed_v2	PMID:24238224 Kao et al., 2013

Note: Hover over icons to view figure legend

Homology

[Close]

BLAST of Nuclear transcription factor Y subunit alpha vs. Ensembl Human
Match: NFYA (nuclear transcription factor Y subunit alpha [Source:HGNC Symbol;Acc:HGNC:7804])

HSP 1 Score: 111.694 bits (278), Expect = 1.587e-27
Identity = 47/58 (81.03%), Postives = 53/58 (91.38%), Query Frame = 2

Query:  509 EEPLYVNAKQYNRILKRRAARTKLEAQGRIPKERKKYLHESRHKHAMNRIRGSGGRFY 682
            EEPLYVNAKQY+RILKRR AR KLEA+G+IPKER+KYLHESRH+HAM R RG GGRF+
Sbjct:  233 EEPLYVNAKQYHRILKRRQARAKLEAEGKIPKERRKYLHESRHRHAMARKRGEGGRFF 290

[Close]

BLAST of Nuclear transcription factor Y subunit alpha vs. Ensembl Human
Match: NFYA (nuclear transcription factor Y subunit alpha [Source:HGNC Symbol;Acc:HGNC:7804])

HSP 1 Score: 112.079 bits (279), Expect = 1.807e-27
Identity = 47/58 (81.03%), Postives = 53/58 (91.38%), Query Frame = 2

Query:  509 EEPLYVNAKQYNRILKRRAARTKLEAQGRIPKERKKYLHESRHKHAMNRIRGSGGRFY 682
            EEPLYVNAKQY+RILKRR AR KLEA+G+IPKER+KYLHESRH+HAM R RG GGRF+
Sbjct:  262 EEPLYVNAKQYHRILKRRQARAKLEAEGKIPKERRKYLHESRHRHAMARKRGEGGRFF 319

[Close]

BLAST of Nuclear transcription factor Y subunit alpha vs. Ensembl Celegans
Match: nfya-1 (Nuclear transcription Factor Y, A (Alpha) subunit [Source:UniProtKB/TrEMBL;Acc:G5EEG1])

HSP 1 Score: 82.0333 bits (201), Expect = 5.603e-17
Identity = 34/57 (59.65%), Postives = 44/57 (77.19%), Query Frame = 2

Query:  509 EEPLYVNAKQYNRILKRRAARTKLEAQGRIPKERKKYLHESRHKHAMNRIRGSGGRF 679
            ++P+ VN KQ+NRI++RR  R +LEA GR+P  R+KYLHESRH HA+ R RG  GRF
Sbjct:  302 QQPMLVNPKQFNRIMRRREMRQQLEASGRLPLARQKYLHESRHLHALKRKRGLDGRF 358

[Close]

BLAST of Nuclear transcription factor Y subunit alpha vs. Ensembl Celegans
Match: nfya-2 (Nuclear transcription Factor Y, A (Alpha) subunit [Source:UniProtKB/TrEMBL;Acc:F3Y5S3])

HSP 1 Score: 75.485 bits (184), Expect = 2.795e-15
Identity = 33/57 (57.89%), Postives = 44/57 (77.19%), Query Frame = 2

Query:  509 EEPLYVNAKQYNRILKRRAARTKLEAQGRIPKERKKYLHESRHKHAMNRIRGSGGRF 679
            E+P+ VN +QY RI+KRR  R K+E  GR+P ER+KY+HESR +HA+ R R +GGRF
Sbjct:  137 EKPIMVNPRQYKRIIKRREMRQKMEDSGRLPLERQKYMHESRRQHALKR-RRTGGRF 192

[Close]

BLAST of Nuclear transcription factor Y subunit alpha vs. Ensembl Celegans
Match: nfya-2 (Nuclear transcription Factor Y, A (Alpha) subunit [Source:UniProtKB/TrEMBL;Acc:F3Y5S3])

HSP 1 Score: 75.0998 bits (183), Expect = 3.279e-15
Identity = 33/57 (57.89%), Postives = 44/57 (77.19%), Query Frame = 2

Query:  509 EEPLYVNAKQYNRILKRRAARTKLEAQGRIPKERKKYLHESRHKHAMNRIRGSGGRF 679
            E+P+ VN +QY RI+KRR  R K+E  GR+P ER+KY+HESR +HA+ R R +GGRF
Sbjct:  146 EKPIMVNPRQYKRIIKRREMRQKMEDSGRLPLERQKYMHESRRQHALKR-RRTGGRF 201

[Close]

BLAST of Nuclear transcription factor Y subunit alpha vs. Ensembl Celegans
Match: nfya-2 (Nuclear transcription Factor Y, A (Alpha) subunit [Source:UniProtKB/TrEMBL;Acc:F3Y5S3])

HSP 1 Score: 68.5514 bits (166), Expect = 6.006e-14
Identity = 31/52 (59.62%), Postives = 40/52 (76.92%), Query Frame = 2

Query:  524 VNAKQYNRILKRRAARTKLEAQGRIPKERKKYLHESRHKHAMNRIRGSGGRF 679
            VN +QY RI+KRR  R K+E  GR+P ER+KY+HESR +HA+ R R +GGRF
Sbjct:    2 VNPRQYKRIIKRREMRQKMEDSGRLPLERQKYMHESRRQHALKR-RRTGGRF 52

[Close]

BLAST of Nuclear transcription factor Y subunit alpha vs. Ensembl Fly
Match: Nf-YA (gene:FBgn0035993 transcript:FBtr0076504)

HSP 1 Score: 100.523 bits (249), Expect = 2.207e-23
Identity = 46/58 (79.31%), Postives = 49/58 (84.48%), Query Frame = 2

Query:  509 EEPLYVNAKQYNRILKRRAARTKLEAQGRIPKERKKYLHESRHKHAMNRIRGSGGRFY 682
            EEPLYVNAKQY RIL RR AR KLE+  RIPKER KYLHESRH+HAMNR RG GGRF+
Sbjct:  288 EEPLYVNAKQYKRILIRRQARAKLES--RIPKERCKYLHESRHRHAMNRARGEGGRFH 343

[Close]

BLAST of Nuclear transcription factor Y subunit alpha vs. Ensembl Zebrafish
Match: nfyal (nuclear transcription factor Y, alpha, like [Source:ZFIN;Acc:ZDB-GENE-040718-491])

HSP 1 Score: 114.005 bits (284), Expect = 1.768e-28
Identity = 49/58 (84.48%), Postives = 53/58 (91.38%), Query Frame = 2

Query:  509 EEPLYVNAKQYNRILKRRAARTKLEAQGRIPKERKKYLHESRHKHAMNRIRGSGGRFY 682
            EEPLYVNAKQY+RILKRR AR KLEA+G+IPKERKKYLHESRHKHAM R RG GGRF+
Sbjct:  234 EEPLYVNAKQYHRILKRRQARAKLEAEGKIPKERKKYLHESRHKHAMQRKRGDGGRFF 291

[Close]

BLAST of Nuclear transcription factor Y subunit alpha vs. Ensembl Zebrafish
Match: nfyal (nuclear transcription factor Y, alpha, like [Source:ZFIN;Acc:ZDB-GENE-040718-491])

HSP 1 Score: 114.775 bits (286), Expect = 2.936e-28
Identity = 49/58 (84.48%), Postives = 53/58 (91.38%), Query Frame = 2

Query:  509 EEPLYVNAKQYNRILKRRAARTKLEAQGRIPKERKKYLHESRHKHAMNRIRGSGGRFY 682
            EEPLYVNAKQY+RILKRR AR KLEA+G+IPKERKKYLHESRHKHAM R RG GGRF+
Sbjct:  297 EEPLYVNAKQYHRILKRRQARAKLEAEGKIPKERKKYLHESRHKHAMQRKRGDGGRFF 354

[Close]

BLAST of Nuclear transcription factor Y subunit alpha vs. Ensembl Zebrafish
Match: nfya (nuclear transcription factor Y, alpha [Source:ZFIN;Acc:ZDB-GENE-010501-1])

HSP 1 Score: 109.383 bits (272), Expect = 8.825e-28
Identity = 47/58 (81.03%), Postives = 53/58 (91.38%), Query Frame = 2

Query:  509 EEPLYVNAKQYNRILKRRAARTKLEAQGRIPKERKKYLHESRHKHAMNRIRGSGGRFY 682
            EEPLYVNAKQY+RILKRR AR KLEA+G+IPKER+KYLHESRH+HAM R RG GGRF+
Sbjct:  128 EEPLYVNAKQYHRILKRRQARAKLEAEGKIPKERRKYLHESRHRHAMARKRGDGGRFF 185

[Close]

BLAST of Nuclear transcription factor Y subunit alpha vs. Ensembl Zebrafish
Match: nfya (nuclear transcription factor Y, alpha [Source:ZFIN;Acc:ZDB-GENE-010501-1])

HSP 1 Score: 111.694 bits (278), Expect = 1.491e-27
Identity = 47/58 (81.03%), Postives = 53/58 (91.38%), Query Frame = 2

Query:  509 EEPLYVNAKQYNRILKRRAARTKLEAQGRIPKERKKYLHESRHKHAMNRIRGSGGRFY 682
            EEPLYVNAKQY+RILKRR AR KLEA+G+IPKER+KYLHESRH+HAM R RG GGRF+
Sbjct:  255 EEPLYVNAKQYHRILKRRQARAKLEAEGKIPKERRKYLHESRHRHAMARKRGDGGRFF 312

[Close]

BLAST of Nuclear transcription factor Y subunit alpha vs. Ensembl Zebrafish
Match: nfya (nuclear transcription factor Y, alpha [Source:ZFIN;Acc:ZDB-GENE-010501-1])

HSP 1 Score: 111.309 bits (277), Expect = 1.733e-27
Identity = 47/58 (81.03%), Postives = 53/58 (91.38%), Query Frame = 2

Query:  509 EEPLYVNAKQYNRILKRRAARTKLEAQGRIPKERKKYLHESRHKHAMNRIRGSGGRFY 682
            EEPLYVNAKQY+RILKRR AR KLEA+G+IPKER+KYLHESRH+HAM R RG GGRF+
Sbjct:  230 EEPLYVNAKQYHRILKRRQARAKLEAEGKIPKERRKYLHESRHRHAMARKRGDGGRFF 287

[Close]

BLAST of Nuclear transcription factor Y subunit alpha vs. Ensembl Xenopus
Match: nfya (nuclear transcription factor Y subunit alpha [Source:NCBI gene;Acc:394530])

HSP 1 Score: 113.235 bits (282), Expect = 4.959e-28
Identity = 67/153 (43.79%), Postives = 83/153 (54.25%), Query Frame = 2

Query:  341 QTVDGHIIPIQFV-TNGTSNSHNLVMMPATTID---------NTNHTESG--SQASTDPVKDEAINNA---------------------------EEPLYVNAKQYNRILKRRAARTKLEAQGRIPKERKKYLHESRHKHAMNRIRGSGGRFY 682
            QT +G  I  Q V  +GT     ++ +PA ++          NTN T SG  +   T PV    +N+                            EEPLYVNAKQY+RILKRR AR KLEA+G+IPKER+KYLHESRH+HAM R RG GGRF+
Sbjct:  158 QTAEGQTIVYQPVNADGTILQQGMITIPAASLAGAQIVQAGANTNTTNSGQGTVTVTLPVTGNMMNSGGMVMMVPGAGTVPTLQRIPLPGAEMLEEEPLYVNAKQYHRILKRRQARAKLEAEGKIPKERRKYLHESRHRHAMARKRGDGGRFF 310

[Close]

BLAST of Nuclear transcription factor Y subunit alpha vs. Ensembl Xenopus
Match: nfya (nuclear transcription factor Y subunit alpha [Source:NCBI gene;Acc:394530])

HSP 1 Score: 112.464 bits (280), Expect = 5.831e-28
Identity = 67/153 (43.79%), Postives = 83/153 (54.25%), Query Frame = 2

Query:  341 QTVDGHIIPIQFV-TNGTSNSHNLVMMPATTID---------NTNHTESG--SQASTDPVKDEAINNA---------------------------EEPLYVNAKQYNRILKRRAARTKLEAQGRIPKERKKYLHESRHKHAMNRIRGSGGRFY 682
            QT +G  I  Q V  +GT     ++ +PA ++          NTN T SG  +   T PV    +N+                            EEPLYVNAKQY+RILKRR AR KLEA+G+IPKER+KYLHESRH+HAM R RG GGRF+
Sbjct:  130 QTAEGQTIVYQPVNADGTILQQGMITIPAASLAGAQIVQAGANTNTTNSGQGTVTVTLPVTGNMMNSGGMVMMVPGAGTVPTLQRIPLPGAEMLEEEPLYVNAKQYHRILKRRQARAKLEAEGKIPKERRKYLHESRHRHAMARKRGDGGRFF 282

[Close]

BLAST of Nuclear transcription factor Y subunit alpha vs. Ensembl Mouse
Match: Nfya (nuclear transcription factor-Y alpha [Source:MGI Symbol;Acc:MGI:97316])

HSP 1 Score: 114.775 bits (286), Expect = 1.330e-28
Identity = 67/153 (43.79%), Postives = 83/153 (54.25%), Query Frame = 2

Query:  341 QTVDGHIIPIQFV-TNGTSNSHNLVMMPATTID---------NTNHTESG--SQASTDPVKDEAINNA---------------------------EEPLYVNAKQYNRILKRRAARTKLEAQGRIPKERKKYLHESRHKHAMNRIRGSGGRFY 682
            QT +G  I  Q V  +GT     ++ +PA ++          NTN T SG  +   T PV    +N+                            EEPLYVNAKQY+RILKRR AR KLEA+G+IPKER+KYLHESRH+HAM R RG GGRF+
Sbjct:  161 QTAEGQTIVYQPVNADGTILQQGMITIPAASLAGAQIVQTGANTNTTSSGQGTVTVTLPVAGNVVNSGGMVMMVPGAGSVPAIQRIPLPGAEMLEEEPLYVNAKQYHRILKRRQARAKLEAEGKIPKERRKYLHESRHRHAMARKRGEGGRFF 313

[Close]

Query:  341 QTVDGHIIPIQFV-TNGTSNSHNLVMMPATTID---------NTNHTESG--SQASTDPVKDEAINNA---------------------------EEPLYVNAKQYNRILKRRAARTKLEAQGRIPKERKKYLHESRHKHAMNRIRGSGGRFY 682
            QT +G  I  Q V  +GT     ++ +PA ++          NTN T SG  +   T PV    +N+                            EEPLYVNAKQY+RILKRR AR KLEA+G+IPKER+KYLHESRH+HAM R RG GGRF+
Sbjct:  161 QTAEGQTIVYQPVNADGTILQQGMITIPAASLAGAQIVQTGANTNTTSSGQGTVTVTLPVAGNVVNSGGMVMMVPGAGSVPAIQRIPLPGAEMLEEEPLYVNAKQYHRILKRRQARAKLEAEGKIPKERRKYLHESRHRHAMARKRGEGGRFF 313

[Close]

BLAST of Nuclear transcription factor Y subunit alpha vs. Ensembl Mouse
Match: Nfya (nuclear transcription factor-Y alpha [Source:MGI Symbol;Acc:MGI:97316])

HSP 1 Score: 114.005 bits (284), Expect = 1.413e-28
Identity = 67/153 (43.79%), Postives = 83/153 (54.25%), Query Frame = 2

Query:  341 QTVDGHIIPIQFV-TNGTSNSHNLVMMPATTID---------NTNHTESG--SQASTDPVKDEAINNA---------------------------EEPLYVNAKQYNRILKRRAARTKLEAQGRIPKERKKYLHESRHKHAMNRIRGSGGRFY 682
            QT +G  I  Q V  +GT     ++ +PA ++          NTN T SG  +   T PV    +N+                            EEPLYVNAKQY+RILKRR AR KLEA+G+IPKER+KYLHESRH+HAM R RG GGRF+
Sbjct:  132 QTAEGQTIVYQPVNADGTILQQGMITIPAASLAGAQIVQTGANTNTTSSGQGTVTVTLPVAGNVVNSGGMVMMVPGAGSVPAIQRIPLPGAEMLEEEPLYVNAKQYHRILKRRQARAKLEAEGKIPKERRKYLHESRHRHAMARKRGEGGRFF 284

[Close]

BLAST of Nuclear transcription factor Y subunit alpha vs. Ensembl Mouse
Match: Nfya (nuclear transcription factor-Y alpha [Source:MGI Symbol;Acc:MGI:97316])

HSP 1 Score: 114.005 bits (284), Expect = 1.413e-28
Identity = 67/153 (43.79%), Postives = 83/153 (54.25%), Query Frame = 2

Query:  341 QTVDGHIIPIQFV-TNGTSNSHNLVMMPATTID---------NTNHTESG--SQASTDPVKDEAINNA---------------------------EEPLYVNAKQYNRILKRRAARTKLEAQGRIPKERKKYLHESRHKHAMNRIRGSGGRFY 682
            QT +G  I  Q V  +GT     ++ +PA ++          NTN T SG  +   T PV    +N+                            EEPLYVNAKQY+RILKRR AR KLEA+G+IPKER+KYLHESRH+HAM R RG GGRF+
Sbjct:  132 QTAEGQTIVYQPVNADGTILQQGMITIPAASLAGAQIVQTGANTNTTSSGQGTVTVTLPVAGNVVNSGGMVMMVPGAGSVPAIQRIPLPGAEMLEEEPLYVNAKQYHRILKRRQARAKLEAEGKIPKERRKYLHESRHRHAMARKRGEGGRFF 284

[Close]

BLAST of Nuclear transcription factor Y subunit alpha vs. Ensembl Mouse
Match: Nfya (nuclear transcription factor-Y alpha [Source:MGI Symbol;Acc:MGI:97316])

HSP 1 Score: 110.153 bits (274), Expect = 4.405e-28
Identity = 47/58 (81.03%), Postives = 53/58 (91.38%), Query Frame = 2

Query:  509 EEPLYVNAKQYNRILKRRAARTKLEAQGRIPKERKKYLHESRHKHAMNRIRGSGGRFY 682
            EEPLYVNAKQY+RILKRR AR KLEA+G+IPKER+KYLHESRH+HAM R RG GGRF+
Sbjct:  126 EEPLYVNAKQYHRILKRRQARAKLEAEGKIPKERRKYLHESRHRHAMARKRGEGGRFF 183

[Close]

BLAST of Nuclear transcription factor Y subunit alpha vs. UniProt/SwissProt
Match: sp|P18576|NFYA_RAT (Nuclear transcription factor Y subunit alpha OS=Rattus norvegicus OX=10116 GN=Nfya PE=1 SV=1)

HSP 1 Score: 114.775 bits (286), Expect = 9.593e-28
Identity = 67/153 (43.79%), Postives = 83/153 (54.25%), Query Frame = 2

Query:  341 QTVDGHIIPIQFV-TNGTSNSHNLVMMPATTID---------NTNHTESG--SQASTDPVKDEAINNA---------------------------EEPLYVNAKQYNRILKRRAARTKLEAQGRIPKERKKYLHESRHKHAMNRIRGSGGRFY 682
            QT +G  I  Q V  +GT     ++ +PA ++          NTN T SG  +   T PV    +N+                            EEPLYVNAKQY+RILKRR AR KLEA+G+IPKER+KYLHESRH+HAM R RG GGRF+
Sbjct:  161 QTAEGQTIVYQPVNADGTILQQGMITIPAASLAGAQIVQTGANTNTTSSGQGTVTVTLPVAGNVVNSGGMVMMVPGAGSVPAIQRIPLPGAEMLEEEPLYVNAKQYHRILKRRQARAKLEAEGKIPKERRKYLHESRHRHAMARKRGEGGRFF 313

[Close]

BLAST of Nuclear transcription factor Y subunit alpha vs. UniProt/SwissProt
Match: sp|Q5E9S2|NFYA_BOVIN (Nuclear transcription factor Y subunit alpha OS=Bos taurus OX=9913 GN=NFYA PE=2 SV=1)

HSP 1 Score: 114.775 bits (286), Expect = 9.789e-28
Identity = 67/153 (43.79%), Postives = 83/153 (54.25%), Query Frame = 2

Query:  341 QTVDGHIIPIQFV-TNGTSNSHNLVMMPATTID---------NTNHTESG--SQASTDPVKDEAINNA---------------------------EEPLYVNAKQYNRILKRRAARTKLEAQGRIPKERKKYLHESRHKHAMNRIRGSGGRFY 682
            QT +G  I  Q V  +GT     ++ +PA ++          NTN T SG  +   T PV    +N+                            EEPLYVNAKQY+RILKRR AR KLEA+G+IPKER+KYLHESRH+HAM R RG GGRF+
Sbjct:  161 QTAEGQTIVYQPVNADGTILQQGMITIPAASLAGAQIVQTGANTNTTSSGQGTVTVTLPVAGNVVNSGGMVMMVPGAGSVPAIQRIPLPGAEMLEEEPLYVNAKQYHRILKRRQARAKLEAEGKIPKERRKYLHESRHRHAMARKRGEGGRFF 313

[Close]

BLAST of Nuclear transcription factor Y subunit alpha vs. UniProt/SwissProt
Match: sp|P23708|NFYA_MOUSE (Nuclear transcription factor Y subunit alpha OS=Mus musculus OX=10090 GN=Nfya PE=1 SV=2)

HSP 1 Score: 112.079 bits (279), Expect = 8.284e-27
Identity = 47/58 (81.03%), Postives = 53/58 (91.38%), Query Frame = 2

Query:  509 EEPLYVNAKQYNRILKRRAARTKLEAQGRIPKERKKYLHESRHKHAMNRIRGSGGRFY 682
            EEPLYVNAKQY+RILKRR AR KLEA+G+IPKER+KYLHESRH+HAM R RG GGRF+
Sbjct:  261 EEPLYVNAKQYHRILKRRQARAKLEAEGKIPKERRKYLHESRHRHAMARKRGEGGRFF 318

[Close]

BLAST of Nuclear transcription factor Y subunit alpha vs. UniProt/SwissProt
Match: sp|P23511|NFYA_HUMAN (Nuclear transcription factor Y subunit alpha OS=Homo sapiens OX=9606 GN=NFYA PE=1 SV=2)

HSP 1 Score: 112.079 bits (279), Expect = 8.677e-27
Identity = 47/58 (81.03%), Postives = 53/58 (91.38%), Query Frame = 2

Query:  509 EEPLYVNAKQYNRILKRRAARTKLEAQGRIPKERKKYLHESRHKHAMNRIRGSGGRFY 682
            EEPLYVNAKQY+RILKRR AR KLEA+G+IPKER+KYLHESRH+HAM R RG GGRF+
Sbjct:  262 EEPLYVNAKQYHRILKRRQARAKLEAEGKIPKERRKYLHESRHRHAMARKRGEGGRFF 319

[Close]

BLAST of Nuclear transcription factor Y subunit alpha vs. UniProt/SwissProt
Match: sp|P06774|HAP2_YEAST (Transcriptional activator HAP2 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) OX=559292 GN=HAP2 PE=1 SV=1)

HSP 1 Score: 96.2857 bits (238), Expect = 1.203e-21
Identity = 44/58 (75.86%), Postives = 47/58 (81.03%), Query Frame = 2

Query:  506 AEEPLYVNAKQYNRILKRRAARTKLEAQGRIPKERKKYLHESRHKHAMNRIRGSGGRF 679
            AE+P YVNAKQY RILKRR AR KLE + RI +ERK YLHESRHKHAM R RG GGRF
Sbjct:  157 AEQPFYVNAKQYYRILKRRYARAKLEEKLRISRERKPYLHESRHKHAMRRPRGEGGRF 214

[Close]

BLAST of Nuclear transcription factor Y subunit alpha vs. TrEMBL
Match: A0A182BAE5 (Nuclear factor-Y subunit A2 OS=Schmidtea mediterranea OX=79327 GN=NF-YA2 PE=2 SV=1)

HSP 1 Score: 441.039 bits (1133), Expect = 1.214e-153
Identity = 238/238 (100.00%), Postives = 238/238 (100.00%), Query Frame = 2

Query:  200 MEISQSEQISVPENEIQYQNVENVVQTNTGPPLVLTTSSDGTSFLAIQTVDGHIIPIQFVTNGTSNSHNLVMMPATTIDNTNHTESGSQASTDPVKDEAINNAEEPLYVNAKQYNRILKRRAARTKLEAQGRIPKERKKYLHESRHKHAMNRIRGSGGRFYXXXXXXXXXXXXXXXXXXXXXDISRKSYVNGSQSNVSYGFSRELVSLAAKTTNNVIIELKLEPPNDSNRMFQTVSAV 913
            MEISQSEQISVPENEIQYQNVENVVQTNTGPPLVLTTSSDGTSFLAIQTVDGHIIPIQFVTNGTSNSHNLVMMPATTIDNTNHTESGSQASTDPVKDEAINNAEEPLYVNAKQYNRILKRRAARTKLEAQGRIPKERKKYLHESRHKHAMNRIRGSGGRFYSVQSEIQNQENNQKNTNVTNNDISRKSYVNGSQSNVSYGFSRELVSLAAKTTNNVIIELKLEPPNDSNRMFQTVSAV
Sbjct:    1 MEISQSEQISVPENEIQYQNVENVVQTNTGPPLVLTTSSDGTSFLAIQTVDGHIIPIQFVTNGTSNSHNLVMMPATTIDNTNHTESGSQASTDPVKDEAINNAEEPLYVNAKQYNRILKRRAARTKLEAQGRIPKERKKYLHESRHKHAMNRIRGSGGRFYSVQSEIQNQENNQKNTNVTNNDISRKSYVNGSQSNVSYGFSRELVSLAAKTTNNVIIELKLEPPNDSNRMFQTVSAV 238

[Close]

BLAST of Nuclear transcription factor Y subunit alpha vs. TrEMBL
Match: A0A182BAE4 (Nuclear factor-Y subunit A1 OS=Schmidtea mediterranea OX=79327 GN=NF-YA1 PE=2 SV=1)

HSP 1 Score: 135.191 bits (339), Expect = 7.997e-34
Identity = 76/152 (50.00%), Postives = 91/152 (59.87%), Query Frame = 2

Query:  293 PLVLTTSSDGTSFLAIQTVDGHIIPIQFVTNGTSNSHNLVMMPATTIDNTNHTESG---SQASTDPV-------------KDEAI-------NNAEEPLYVNAKQYNRILKRRAARTKLEAQGRIPKERKKYLHESRHKHAMNRIRGSGGRF 679
            P+VL     G + L IQT DG+IIP+Q  +N   N   ++M+  + I   +   +G   S AS D V             + E I       N  EEPLYVNAKQYNRILKRR AR KLEAQGR+PK R KYLHESRHKHAMNR+RG GG+F
Sbjct:   23 PIVLAQGQGGNTILGIQTSDGNIIPLQLASN--PNGSQVMMVVPSQISTQSANLTGQVTSVASHDQVPQCVQPTQIIGSYETEQISEENSQQNAQEEPLYVNAKQYNRILKRRQARAKLEAQGRLPKGRSKYLHESRHKHAMNRVRGEGGKF 172

[Close]

BLAST of Nuclear transcription factor Y subunit alpha vs. TrEMBL
Match: A0A0F7GYF7 (Nuclear factor Y complex A (Fragment) OS=Schmidtea mediterranea OX=79327 PE=2 SV=1)

HSP 1 Score: 135.191 bits (339), Expect = 8.241e-34
Identity = 76/152 (50.00%), Postives = 91/152 (59.87%), Query Frame = 2

Query:  293 PLVLTTSSDGTSFLAIQTVDGHIIPIQFVTNGTSNSHNLVMMPATTIDNTNHTESG---SQASTDPV-------------KDEAI-------NNAEEPLYVNAKQYNRILKRRAARTKLEAQGRIPKERKKYLHESRHKHAMNRIRGSGGRF 679
            P+VL     G + L IQT DG+IIP+Q  +N   N   ++M+  + I   +   +G   S AS D V             + E I       N  EEPLYVNAKQYNRILKRR AR KLEAQGR+PK R KYLHESRHKHAMNR+RG GG+F
Sbjct:   25 PIVLAQGQGGNTILGIQTSDGNIIPLQLASN--PNGSQVMMVVPSQISTQSANLTGQVTSVASHDQVPQCVQPTQIIGSYETEQISEENSQQNAQEEPLYVNAKQYNRILKRRQARAKLEAQGRLPKGRSKYLHESRHKHAMNRVRGEGGKF 174

[Close]

BLAST of Nuclear transcription factor Y subunit alpha vs. TrEMBL
Match: A0A1S3JZW1 (nuclear transcription factor Y subunit alpha isoform X3 OS=Lingula unguis OX=7574 GN=LOC106177425 PE=4 SV=1)

HSP 1 Score: 126.331 bits (316), Expect = 1.123e-29
Identity = 68/122 (55.74%), Postives = 78/122 (63.93%), Query Frame = 2

Query:  332 LAIQTVDGHI---IPIQFVTNGTSNSHNLVMMPATTIDNTNHTESGSQASTD--PVKDEAINNAEEPLYVNAKQYNRILKRRAARTKLEAQGRIPKERKKYLHESRHKHAMNRIRGSGGRFY 682
            LA QT        +P      GT     ++MM  T   NT  T SG  A+    P+  + +   EEPLYVNAKQY+RILKRR AR KLEA+G+IPKERKKYLHESRHKHAMNR RG GGRFY
Sbjct:  146 LATQTAQASTASSMPTTITIPGTGGQGQVIMMVPT---NTTSTASGGGAAMQRLPLPGQEVME-EEPLYVNAKQYHRILKRRQARAKLEAEGKIPKERKKYLHESRHKHAMNRSRGEGGRFY 263

[Close]

BLAST of Nuclear transcription factor Y subunit alpha vs. TrEMBL
Match: A0A1S3JZD7 (nuclear transcription factor Y subunit alpha isoform X1 OS=Lingula unguis OX=7574 GN=LOC106177425 PE=4 SV=1)

HSP 1 Score: 126.331 bits (316), Expect = 1.676e-29
Identity = 68/122 (55.74%), Postives = 78/122 (63.93%), Query Frame = 2

Query:  332 LAIQTVDGHI---IPIQFVTNGTSNSHNLVMMPATTIDNTNHTESGSQASTD--PVKDEAINNAEEPLYVNAKQYNRILKRRAARTKLEAQGRIPKERKKYLHESRHKHAMNRIRGSGGRFY 682
            LA QT        +P      GT     ++MM  T   NT  T SG  A+    P+  + +   EEPLYVNAKQY+RILKRR AR KLEA+G+IPKERKKYLHESRHKHAMNR RG GGRFY
Sbjct:  168 LATQTAQASTASSMPTTITIPGTGGQGQVIMMVPT---NTTSTASGGGAAMQRLPLPGQEVME-EEPLYVNAKQYHRILKRRQARAKLEAEGKIPKERKKYLHESRHKHAMNRSRGEGGRFY 285

[Close]

BLAST of Nuclear transcription factor Y subunit alpha vs. Ensembl Cavefish
Match: nfyal (nuclear transcription factor Y, alpha, like [Source:ZFIN;Acc:ZDB-GENE-040718-491])

HSP 1 Score: 113.235 bits (282), Expect = 1.268e-28
Identity = 63/155 (40.65%), Postives = 80/155 (51.61%), Query Frame = 2

Query:  341 QTVDGHIIPIQFV-TNGTSNSHNLVMMPATTIDNTNHTESGSQASTD-------------PVKDEAINNA---------------------------EEPLYVNAKQYNRILKRRAARTKLEAQGRIPKERKKYLHESRHKHAMNRIRGSGGRFY 682
            QT +G  I  Q V  +GT     ++ +PA T+  T   ++   A+T              P+    +N                             EEPLYVNAKQY+RILKRR AR KLEA+G+IPKER+KYLHESRH+HAM R RG GGRF+
Sbjct:  100 QTAEGQTIVYQPVNADGTVLQQGMITIPAGTLTGTQIVQAAGGANTSTTNSGQGTVTVTLPMSGNVVNTGGMVMMVPGGGTVPTIQRIPLPGAEMLEEEPLYVNAKQYHRILKRRQARAKLEAEGKIPKERRKYLHESRHRHAMQRKRGDGGRFF 254

[Close]

BLAST of Nuclear transcription factor Y subunit alpha vs. Ensembl Sea Lamprey
Match: nfya (nuclear transcription factor Y, alpha [Source:ZFIN;Acc:ZDB-GENE-010501-1])

HSP 1 Score: 114.005 bits (284), Expect = 3.115e-29
Identity = 49/58 (84.48%), Postives = 53/58 (91.38%), Query Frame = 2

Query:  509 EEPLYVNAKQYNRILKRRAARTKLEAQGRIPKERKKYLHESRHKHAMNRIRGSGGRFY 682
            EEPLYVNAKQY+RILKRR AR KLEA+GRIPKERKKYLHESRH+HAM R RG GGRF+
Sbjct:  263 EEPLYVNAKQYHRILKRRQARAKLEAEGRIPKERKKYLHESRHRHAMQRQRGEGGRFH 320

[Close]

BLAST of Nuclear transcription factor Y subunit alpha vs. Ensembl Yeast
Match: HAP2 (Subunit of the Hap2p/3p/4p/5p CCAAT-binding complex; complex is heme-activated and glucose-repressed; complex is a transcriptional activator and global regulator of respiratory gene expression; contains sequences sufficient for both complex assembly and DNA binding; respiratory defect of the null mutant is functionally complemented by human NFYA [Source:SGD;Acc:S000003206])

HSP 1 Score: 96.2857 bits (238), Expect = 1.732e-23
Identity = 44/58 (75.86%), Postives = 47/58 (81.03%), Query Frame = 2

Query:  506 AEEPLYVNAKQYNRILKRRAARTKLEAQGRIPKERKKYLHESRHKHAMNRIRGSGGRF 679
            AE+P YVNAKQY RILKRR AR KLE + RI +ERK YLHESRHKHAM R RG GGRF
Sbjct:  157 AEQPFYVNAKQYYRILKRRYARAKLEEKLRISRERKPYLHESRHKHAMRRPRGEGGRF 214

[Close]

BLAST of Nuclear transcription factor Y subunit alpha vs. Ensembl Nematostella
Match: EDO27514 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7T919])

HSP 1 Score: 96.2857 bits (238), Expect = 9.871e-25
Identity = 43/61 (70.49%), Postives = 51/61 (83.61%), Query Frame = 2

Query:  497 INNAEEPLYVNAKQYNRILKRRAARTKLEAQGRIPKERKKYLHESRHKHAMNRIRGSGGRF 679
            +   +EPLYVNAKQY+RI+KRR AR KLEA+G+IPK RKKYLHESRH+HA  R R +GGRF
Sbjct:    1 METLDEPLYVNAKQYHRIIKRRQARAKLEAEGKIPKVRKKYLHESRHQHACRRKRSNGGRF 61

[Close]

BLAST of Nuclear transcription factor Y subunit alpha vs. Ensembl Nematostella
Match: EDO48713 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RII3])

HSP 1 Score: 95.1301 bits (235), Expect = 1.381e-24
Identity = 43/61 (70.49%), Postives = 51/61 (83.61%), Query Frame = 2

Query:  497 INNAEEPLYVNAKQYNRILKRRAARTKLEAQGRIPKERKKYLHESRHKHAMNRIRGSGGRF 679
            +   +EPLYVNAKQY+RI+KRR AR KLEA+G+IPK RKKYLHESRH+HA  R R +GGRF
Sbjct:    1 METLDEPLYVNAKQYHRIIKRRQARAKLEAEGKIPKVRKKYLHESRHQHACRRKRSNGGRF 61

[Close]

BLAST of Nuclear transcription factor Y subunit alpha vs. Ensembl Medaka
Match: nfyal (nuclear transcription factor Y subunit alpha [Source:NCBI gene;Acc:101159350])

HSP 1 Score: 116.316 bits (290), Expect = 1.933e-29
Identity = 68/154 (44.16%), Postives = 83/154 (53.90%), Query Frame = 2

Query:  341 QTVDGHIIPIQFV-TNGTSNSHNLVMMPATTID----------NTNHTESG--SQASTDPVKDEAINNA---------------------------EEPLYVNAKQYNRILKRRAARTKLEAQGRIPKERKKYLHESRHKHAMNRIRGSGGRFY 682
            QT DG  I  Q V T+G+     ++ +PA ++           NTN T SG  +   T PV    +N                             EEPLYVNAKQY+RILKRR AR KLEA+G+IPKER+KYLHESRH+HAM R RG GGRF+
Sbjct:  132 QTADGQTIVYQPVNTDGSVLQQGMITIPAASLAGAQIVQAGGANTNTTNSGQGTVTVTLPVSGNMVNAGGMVMMVPGSGGVPTMQRIPLPGAEMLEEEPLYVNAKQYHRILKRRQARAKLEAEGKIPKERRKYLHESRHRHAMQRKRGDGGRFF 285

[Close]

BLAST of Nuclear transcription factor Y subunit alpha vs. Planmine SMEST
Match: SMESG000010136.1 (SMESG000010136.1)

HSP 1 Score: 297.745 bits (761), Expect = 8.901e-102
Identity = 167/167 (100.00%), Postives = 167/167 (100.00%), Query Frame = 2

Query:  413 MMPATTIDNTNHTESGSQASTDPVKDEAINNAEEPLYVNAKQYNRILKRRAARTKLEAQGRIPKERKKYLHESRHKHAMNRIRGSGGRFYXXXXXXXXXXXXXXXXXXXXXDISRKSYVNGSQSNVSYGFSRELVSLAAKTTNNVIIELKLEPPNDSNRMFQTVSAV 913
            MMPATTIDNTNHTESGSQASTDPVKDEAINNAEEPLYVNAKQYNRILKRRAARTKLEAQGRIPKERKKYLHESRHKHAMNRIRGSGGRFYSVQSEIQNQENNQKNTNVTNNDISRKSYVNGSQSNVSYGFSRELVSLAAKTTNNVIIELKLEPPNDSNRMFQTVSAV
Sbjct:    1 MMPATTIDNTNHTESGSQASTDPVKDEAINNAEEPLYVNAKQYNRILKRRAARTKLEAQGRIPKERKKYLHESRHKHAMNRIRGSGGRFYSVQSEIQNQENNQKNTNVTNNDISRKSYVNGSQSNVSYGFSRELVSLAAKTTNNVIIELKLEPPNDSNRMFQTVSAV 167

[Close]

BLAST of Nuclear transcription factor Y subunit alpha vs. Planmine SMEST
Match: SMESG000010136.1 (SMESG000010136.1)

HSP 1 Score: 295.049 bits (754), Expect = 9.487e-101
Identity = 166/166 (100.00%), Postives = 166/166 (100.00%), Query Frame = 2

Query:  416 MPATTIDNTNHTESGSQASTDPVKDEAINNAEEPLYVNAKQYNRILKRRAARTKLEAQGRIPKERKKYLHESRHKHAMNRIRGSGGRFYXXXXXXXXXXXXXXXXXXXXXDISRKSYVNGSQSNVSYGFSRELVSLAAKTTNNVIIELKLEPPNDSNRMFQTVSAV 913
            MPATTIDNTNHTESGSQASTDPVKDEAINNAEEPLYVNAKQYNRILKRRAARTKLEAQGRIPKERKKYLHESRHKHAMNRIRGSGGRFYSVQSEIQNQENNQKNTNVTNNDISRKSYVNGSQSNVSYGFSRELVSLAAKTTNNVIIELKLEPPNDSNRMFQTVSAV
Sbjct:    1 MPATTIDNTNHTESGSQASTDPVKDEAINNAEEPLYVNAKQYNRILKRRAARTKLEAQGRIPKERKKYLHESRHKHAMNRIRGSGGRFYSVQSEIQNQENNQKNTNVTNNDISRKSYVNGSQSNVSYGFSRELVSLAAKTTNNVIIELKLEPPNDSNRMFQTVSAV 166

[Close]

BLAST of Nuclear transcription factor Y subunit alpha vs. Planmine SMEST
Match: SMESG000045451.1 (SMESG000045451.1)

HSP 1 Score: 115.161 bits (287), Expect = 1.866e-30
Identity = 50/60 (83.33%), Postives = 53/60 (88.33%), Query Frame = 2

Query:  500 NNAEEPLYVNAKQYNRILKRRAARTKLEAQGRIPKERKKYLHESRHKHAMNRIRGSGGRF 679
            N  EEPLYVNAKQYNRILKRR AR KLEAQGR+PK R KYLHESRHKHAMNR+RG GG+F
Sbjct:   54 NAQEEPLYVNAKQYNRILKRRQARAKLEAQGRLPKGRSKYLHESRHKHAMNRVRGEGGKF 113

[Close]

BLAST of Nuclear transcription factor Y subunit alpha vs. Planmine SMEST
Match: SMESG000045451.1 (SMESG000045451.1)

HSP 1 Score: 115.161 bits (287), Expect = 2.038e-30
Identity = 50/60 (83.33%), Postives = 53/60 (88.33%), Query Frame = 2

Query:  500 NNAEEPLYVNAKQYNRILKRRAARTKLEAQGRIPKERKKYLHESRHKHAMNRIRGSGGRF 679
            N  EEPLYVNAKQYNRILKRR AR KLEAQGR+PK R KYLHESRHKHAMNR+RG GG+F
Sbjct:   53 NAQEEPLYVNAKQYNRILKRRQARAKLEAQGRLPKGRSKYLHESRHKHAMNRVRGEGGKF 112

[Close]

BLAST of Nuclear transcription factor Y subunit alpha vs. Planmine SMEST
Match: SMESG000031441.1 (SMESG000031441.1)

HSP 1 Score: 68.1662 bits (165), Expect = 1.307e-13
Identity = 35/62 (56.45%), Postives = 44/62 (70.97%), Query Frame = 2

Query:  497 INNAEEP-LYVNAKQYNRILKRRAARTKLEAQGRIPKERKKYLHESRHKHAMNRIRGSGGRF 679
            IN  + P L+VN KQYNRILKRR AR KL+ +     ER +Y++ESR KHA+NR R  GG+F
Sbjct:   79 INQNDPPVLFVNPKQYNRILKRRVARAKLKLRT---GERSRYMYESRRKHALNRARSIGGQF 137

The following BLAST results are available for this feature:

BLAST of Nuclear transcription factor Y subunit alpha vs. Ensembl Human
BLAST of Nuclear transcription factor Y subunit alpha vs. Ensembl Celegans
BLAST of Nuclear transcription factor Y subunit alpha vs. Ensembl Fly
BLAST of Nuclear transcription factor Y subunit alpha vs. Ensembl Zebrafish
BLAST of Nuclear transcription factor Y subunit alpha vs. Ensembl Xenopus
BLAST of Nuclear transcription factor Y subunit alpha vs. Ensembl Mouse
BLAST of Nuclear transcription factor Y subunit alpha vs. UniProt/SwissProt
BLAST of Nuclear transcription factor Y subunit alpha vs. TrEMBL
BLAST of Nuclear transcription factor Y subunit alpha vs. Ensembl Cavefish
BLAST of Nuclear transcription factor Y subunit alpha vs. Ensembl Sea Lamprey
BLAST of Nuclear transcription factor Y subunit alpha vs. Ensembl Yeast
BLAST of Nuclear transcription factor Y subunit alpha vs. Ensembl Nematostella
BLAST of Nuclear transcription factor Y subunit alpha vs. Ensembl Medaka
BLAST of Nuclear transcription factor Y subunit alpha vs. Planmine SMEST

BLAST of Nuclear transcription factor Y subunit alpha vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 2


Match Name	E-value	Identity	Description
NFYA	1.587e-27	81.03	nuclear transcription factor Y subunit alpha [Sour...	[more]
NFYA	1.807e-27	81.03	nuclear transcription factor Y subunit alpha [Sour...	[more]

BLAST of Nuclear transcription factor Y subunit alpha vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 4


Match Name	E-value	Identity	Description
nfya-1	5.603e-17	59.65	Nuclear transcription Factor Y, A (Alpha) subunit ...	[more]
nfya-2	2.795e-15	57.89	Nuclear transcription Factor Y, A (Alpha) subunit ...	[more]
nfya-2	3.279e-15	57.89	Nuclear transcription Factor Y, A (Alpha) subunit ...	[more]
nfya-2	6.006e-14	59.62	Nuclear transcription Factor Y, A (Alpha) subunit ...	[more]

BLAST of Nuclear transcription factor Y subunit alpha vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 1


Match Name	E-value	Identity	Description
Nf-YA	2.207e-23	79.31	gene:FBgn0035993 transcript:FBtr0076504	[more]

BLAST of Nuclear transcription factor Y subunit alpha vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5


Match Name	E-value	Identity	Description
nfyal	1.768e-28	84.48	nuclear transcription factor Y, alpha, like [Sourc...	[more]
nfyal	2.936e-28	84.48	nuclear transcription factor Y, alpha, like [Sourc...	[more]
nfya	8.825e-28	81.03	nuclear transcription factor Y, alpha [Source:ZFIN...	[more]
nfya	1.491e-27	81.03	nuclear transcription factor Y, alpha [Source:ZFIN...	[more]
nfya	1.733e-27	81.03	nuclear transcription factor Y, alpha [Source:ZFIN...	[more]

BLAST of Nuclear transcription factor Y subunit alpha vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 2


Match Name	E-value	Identity	Description
nfya	4.959e-28	43.79	nuclear transcription factor Y subunit alpha [Sour...	[more]
nfya	5.831e-28	43.79	nuclear transcription factor Y subunit alpha [Sour...	[more]

BLAST of Nuclear transcription factor Y subunit alpha vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5


Match Name	E-value	Identity	Description
Nfya	1.330e-28	43.79	nuclear transcription factor-Y alpha [Source:MGI S...	[more]
Nfya	1.330e-28	43.79	nuclear transcription factor-Y alpha [Source:MGI S...	[more]
Nfya	1.413e-28	43.79	nuclear transcription factor-Y alpha [Source:MGI S...	[more]
Nfya	1.413e-28	43.79	nuclear transcription factor-Y alpha [Source:MGI S...	[more]
Nfya	4.405e-28	81.03	nuclear transcription factor-Y alpha [Source:MGI S...	[more]

BLAST of Nuclear transcription factor Y subunit alpha vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5


Match Name	E-value	Identity	Description
sp\|P18576\|NFYA_RAT	9.593e-28	43.79	Nuclear transcription factor Y subunit alpha OS=Ra...	[more]
sp\|Q5E9S2\|NFYA_BOVIN	9.789e-28	43.79	Nuclear transcription factor Y subunit alpha OS=Bo...	[more]
sp\|P23708\|NFYA_MOUSE	8.284e-27	81.03	Nuclear transcription factor Y subunit alpha OS=Mu...	[more]
sp\|P23511\|NFYA_HUMAN	8.677e-27	81.03	Nuclear transcription factor Y subunit alpha OS=Ho...	[more]
sp\|P06774\|HAP2_YEAST	1.203e-21	75.86	Transcriptional activator HAP2 OS=Saccharomyces ce...	[more]

BLAST of Nuclear transcription factor Y subunit alpha vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5


Match Name	E-value	Identity	Description
A0A182BAE5	1.214e-153	100.00	Nuclear factor-Y subunit A2 OS=Schmidtea mediterra...	[more]
A0A182BAE4	7.997e-34	50.00	Nuclear factor-Y subunit A1 OS=Schmidtea mediterra...	[more]
A0A0F7GYF7	8.241e-34	50.00	Nuclear factor Y complex A (Fragment) OS=Schmidtea...	[more]
A0A1S3JZW1	1.123e-29	55.74	nuclear transcription factor Y subunit alpha isofo...	[more]
A0A1S3JZD7	1.676e-29	55.74	nuclear transcription factor Y subunit alpha isofo...	[more]

BLAST of Nuclear transcription factor Y subunit alpha vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 1


Match Name	E-value	Identity	Description
nfyal	1.268e-28	40.65	nuclear transcription factor Y, alpha, like [Sourc...	[more]

BLAST of Nuclear transcription factor Y subunit alpha vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 1


Match Name	E-value	Identity	Description
nfya	3.115e-29	84.48	nuclear transcription factor Y, alpha [Source:ZFIN...	[more]

BLAST of Nuclear transcription factor Y subunit alpha vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 1


Match Name	E-value	Identity	Description
HAP2	1.732e-23	75.86	Subunit of the Hap2p/3p/4p/5p CCAAT-binding comple...	[more]

BLAST of Nuclear transcription factor Y subunit alpha vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 2


Match Name	E-value	Identity	Description
EDO27514	9.871e-25	70.49	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO48713	1.381e-24	70.49	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]

BLAST of Nuclear transcription factor Y subunit alpha vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 1


Match Name	E-value	Identity	Description
nfyal	1.933e-29	44.16	nuclear transcription factor Y subunit alpha [Sour...	[more]

BLAST of Nuclear transcription factor Y subunit alpha vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5


Match Name	E-value	Identity	Description
SMESG000010136.1	8.901e-102	100.00	SMESG000010136.1	[more]
SMESG000010136.1	9.487e-101	100.00	SMESG000010136.1	[more]
SMESG000045451.1	1.866e-30	83.33	SMESG000045451.1	[more]
SMESG000045451.1	2.038e-30	83.33	SMESG000045451.1	[more]
SMESG000031441.1	1.307e-13	56.45	SMESG000031441.1	[more]

Analyses

This transcript is derived from or has results from the following analyses


Analysis Name	Date Performed
Embryonic Stages	2016-07-25
Schmidtea mediterranea smed_20140614 BLASTX Human e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL	2020-05-01
Schmidtea mediterranea Sexual smed_20140614 transcriptome	2016-07-25
Schmidtea mediteranean smed_20140614 Interproscan	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST	2020-05-08

Sequences

The following sequences are available for this feature:

transcript sequence
protein sequence

transcript sequence

>SMED30013473 ID=SMED30013473|Name=Nuclear transcription factor Y subunit alpha|organism=Schmidtea mediterranea sexual|type=transcript|length=1078bp
TATATATCTTGCTTTTTTCCCAGTTTATTAAATAAGTATTATATTTTAAC
ATTCTTTTAAAAAATTTAGAATTAATAATACATAACCTTTGTTAAAGTAA
CAGTTTACTATTAATCTGTATATTAATTTTCATTTGATTTGCTACTGGAA
TTGATCCGAAATACATATCCAATCATTTAATGCTACAGATCTGGACCCAA
TGGAAATAAGTCAAAGTGAACAAATTTCAGTCCCAGAAAATGAAATTCAA
TATCAGAATGTTGAAAATGTAGTCCAAACAAATACTGGCCCTCCTTTAGT
TTTAACAACCAGTTCCGATGGAACATCGTTTCTTGCGATACAGACAGTTG
ACGGTCACATTATCCCCATACAATTCGTCACAAATGGAACATCCAACAGC
CACAACCTAGTAATGATGCCAGCAACAACTATTGATAATACAAATCACAC
TGAGAGTGGTTCTCAAGCATCTACCGATCCAGTAAAAGATGAAGCAATAA
ATAATGCGGAAGAACCGCTTTATGTCAACGCAAAACAATATAATCGAATT
TTAAAAAGACGAGCAGCAAGAACAAAATTAGAAGCCCAAGGACGAATTCC
AAAAGAAAGGAAAAAATACCTACATGAATCAAGACATAAACACGCCATGA
ATCGAATACGTGGATCAGGAGGTAGATTTTATTCAGTTCAAAGTGAAATT
CAAAATCAAGAAAACAATCAAAAAAATACAAATGTCACTAACAATGACAT
ATCTAGAAAGAGTTATGTCAACGGTTCACAATCAAATGTTTCATACGGAT
TTTCACGAGAATTGGTGTCTCTAGCGGCTAAAACCACAAATAATGTTATC
ATAGAACTTAAGCTTGAACCACCGAATGATTCAAATCGAATGTTTCAAAC
TGTCAGTGCAGTCTGAAATTGACTAAATATGTCGCATTTATTGTTTATAC
TGCATTTTGTTTGACTGTATCTCATTATAATAGATCGTAAATTATTATTT
TTGCCGTAGTAAAAAATAACTAATTTTTTGTCAATTTTTTTTAATTAATC
GAAGATTAATTCTCTTTTATTAATTGTG

protein sequence of SMED30013473-orf-1

>SMED30013473-orf-1 ID=SMED30013473-orf-1|Name=SMED30013473-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=239bp
MEISQSEQISVPENEIQYQNVENVVQTNTGPPLVLTTSSDGTSFLAIQTV
DGHIIPIQFVTNGTSNSHNLVMMPATTIDNTNHTESGSQASTDPVKDEAI
NNAEEPLYVNAKQYNRILKRRAARTKLEAQGRIPKERKKYLHESRHKHAM
NRIRGSGGRFYSVQSEIQNQENNQKNTNVTNNDISRKSYVNGSQSNVSYG
FSRELVSLAAKTTNNVIIELKLEPPNDSNRMFQTVSAV*

Annotated Terms

The following terms have been associated with this transcript:

Vocabulary: **molecular function**
Term	Definition
GO:0003677	DNA binding
GO:0003700	transcription factor activity, sequence-specific DNA binding

Vocabulary: **cellular component**
Term	Definition
GO:0016602	CCAAT-binding factor complex

Vocabulary: **Planarian Anatomy**
Term	Definition
PLANA:0000099	neuron
PLANA:0000208	testis
PLANA:0000418	head

Vocabulary: **INTERPRO**
Term	Definition
IPR001289	NFYA

Vocabulary: **biological process**
Term	Definition
GO:0006355	regulation of transcription, DNA-templated

InterPro

Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01


IPR Term	IPR Description	Source	Source Term	Source Description	Alignment
IPR001289	Nuclear transcription factor Y subunit A	PRINTS	PR00616	CCAATSUBUNTB	coord: 106..128 score: 76.57 coord: 137..160 score: 79.4
IPR001289	Nuclear transcription factor Y subunit A	SMART	SM00521	cbf3	coord: 102..163 e-value: 5.1E-35 score: 132.3
IPR001289	Nuclear transcription factor Y subunit A	PFAM	PF02045	CBFB_NFYA	coord: 105..160 e-value: 1.1E-28 score: 99.6
IPR001289	Nuclear transcription factor Y subunit A	PANTHER	PTHR12632	TRANSCRIPTION FACTOR NF-Y ALPHA-RELATED	coord: 28..188
IPR001289	Nuclear transcription factor Y subunit A	PROSITE	PS51152	NFYA_HAP2_2	coord: 103..163 score: 36.286
None	No IPR available	PANTHER	PTHR12632:SF6	NUCLEAR TRANSCRIPTION FACTOR Y SUBUNIT ALPHA	coord: 28..188