Rho-related GTP-binding protein

Overview


Name	Rho-related GTP-binding protein
Smed ID	SMED30013470
Length (bp)	828

Neoblast Clusters

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Overview

Single cell RNA-seq of pluripotent neoblasts and its early progenies

We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)

Explore this single cell expression dataset with our NB Cluster Shiny App

Neoblast Population

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.

Expression of Rho-related GTP-binding protein (SMED30013470) t-SNE clustered cells

Violin plots show distribution of expression levels for Rho-related GTP-binding protein (SMED30013470) in cells (dots) of each of the 12 neoblast clusters.

Sub-lethal Irradiated Surviving X1 and X2 Cell Population

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of Rho-related GTP-binding protein (SMED30013470) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for Rho-related GTP-binding protein (SMED30013470) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

Anatomical Expression

PAGE et. al., 2020

SMED30013470

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE

PAGE Curations: 10

Expressed In	Reference Transcript	Gene Models	Published Transcript	Transcriptome	Publication
protonephridia	SMED30013470	h1SMcG0017964	dd_Smed_v4_813_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
nervous system	SMED30013470	h1SMcG0017964	dd_Smed_v4_813_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
epidermis	SMED30013470	h1SMcG0017964	dd_Smed_v4_813_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
cephalic ganglia	SMED30013470	h1SMcG0017964	dd_Smed_v4_813_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
muscle cell	SMED30013470	h1SMcG0017964	dd_Smed_v4_813_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
neoblast	SMED30013470	h1SMcG0017964	dd_Smed_v4_813_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
parenchymal cell	SMED30013470	h1SMcG0017964	dd_Smed_v4_813_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
non-ciliated neuron	SMED30013470	h1SMcG0017964	dd_Smed_v4_813_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
Smed sexual biotype	SMED30013470	h1SMcG0017964	Contig42731	uc_Smed_v2	PMID:29674431 Fincher et al., 2018
Smed sexual biotype	SMED30013470	h1SMcG0017964	Contig42731	newmark_ests	PMID:29674431 Fincher et al., 2018

Note: Hover over icons to view figure legend

Homology

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BLAST of Rho-related GTP-binding protein vs. Ensembl Human
Match: RHOA (ras homolog family member A [Source:HGNC Symbol;Acc:HGNC:667])

HSP 1 Score: 329.717 bits (844), Expect = 6.011e-115
Identity = 161/191 (84.29%), Postives = 168/191 (87.96%), Query Frame = 1

Query:   31 MSAIRKKLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYVADIEVDNKQVELALWDTAGQEDYDRLRPLSYPDTDVILMCFSIDSTDSLENIVEKWYPEVKHFCPNVPIILVGNKKDLRNDERARHELAKMRQELVKYEDGLLTADKINAVKYLECSAKTKDGVREVFETATRAALSVKHKKKKCNIL 603
            M+AIRKKLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYVADIEVD KQVELALWDTAGQEDYDRLRPLSYPDTDVILMCFSIDS DSLENI EKW PEVKHFCPNVPIILVGNKKDLRNDE  R ELAKM+QE VK E+G   A++I A  Y+ECSAKTKDGVREVFE ATRAAL  +  KKK   L
Sbjct:    1 MAAIRKKLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYVADIEVDGKQVELALWDTAGQEDYDRLRPLSYPDTDVILMCFSIDSPDSLENIPEKWTPEVKHFCPNVPIILVGNKKDLRNDEHTRRELAKMKQEPVKPEEGRDMANRIGAFGYMECSAKTKDGVREVFEMATRAALQARRGKKKSGCL 191

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BLAST of Rho-related GTP-binding protein vs. Ensembl Human
Match: RHOC (ras homolog family member C [Source:HGNC Symbol;Acc:HGNC:669])

HSP 1 Score: 324.709 bits (831), Expect = 6.807e-113
Identity = 158/193 (81.87%), Postives = 170/193 (88.08%), Query Frame = 1

Query:   31 MSAIRKKLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYVADIEVDNKQVELALWDTAGQEDYDRLRPLSYPDTDVILMCFSIDSTDSLENIVEKWYPEVKHFCPNVPIILVGNKKDLRNDERARHELAKMRQELVKYEDGLLTADKINAVKYLECSAKTKDGVREVFETATRAALSVKHKKKK--CNIL 603
            M+AIRKKLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENY+ADIEVD KQVELALWDTAGQEDYDRLRPLSYPDTDVILMCFSIDS DSLENI EKW PEVKHFCPNVPIILVGNKKDLR DE  R ELAKM+QE V+ E+G   A++I+A  YLECSAKTK+GVREVFE ATRA L V+  K++  C IL
Sbjct:    1 MAAIRKKLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYIADIEVDGKQVELALWDTAGQEDYDRLRPLSYPDTDVILMCFSIDSPDSLENIPEKWTPEVKHFCPNVPIILVGNKKDLRQDEHTRRELAKMKQEPVRSEEGRDMANRISAFGYLECSAKTKEGVREVFEMATRAGLQVRKNKRRRGCPIL 193

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Query:   31 MSAIRKKLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYVADIEVDNKQVELALWDTAGQEDYDRLRPLSYPDTDVILMCFSIDSTDSLENIVEKWYPEVKHFCPNVPIILVGNKKDLRNDERARHELAKMRQELVKYEDGLLTADKINAVKYLECSAKTKDGVREVFETATRAALSVKHKKKK--CNIL 603
            M+AIRKKLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENY+ADIEVD KQVELALWDTAGQEDYDRLRPLSYPDTDVILMCFSIDS DSLENI EKW PEVKHFCPNVPIILVGNKKDLR DE  R ELAKM+QE V+ E+G   A++I+A  YLECSAKTK+GVREVFE ATRA L V+  K++  C IL
Sbjct:    1 MAAIRKKLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYIADIEVDGKQVELALWDTAGQEDYDRLRPLSYPDTDVILMCFSIDSPDSLENIPEKWTPEVKHFCPNVPIILVGNKKDLRQDEHTRRELAKMKQEPVRSEEGRDMANRISAFGYLECSAKTKEGVREVFEMATRAGLQVRKNKRRRGCPIL 193

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Query:   31 MSAIRKKLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYVADIEVDNKQVELALWDTAGQEDYDRLRPLSYPDTDVILMCFSIDSTDSLENIVEKWYPEVKHFCPNVPIILVGNKKDLRNDERARHELAKMRQELVKYEDGLLTADKINAVKYLECSAKTKDGVREVFETATRAALSVKHKKKK--CNIL 603
            M+AIRKKLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENY+ADIEVD KQVELALWDTAGQEDYDRLRPLSYPDTDVILMCFSIDS DSLENI EKW PEVKHFCPNVPIILVGNKKDLR DE  R ELAKM+QE V+ E+G   A++I+A  YLECSAKTK+GVREVFE ATRA L V+  K++  C IL
Sbjct:    1 MAAIRKKLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYIADIEVDGKQVELALWDTAGQEDYDRLRPLSYPDTDVILMCFSIDSPDSLENIPEKWTPEVKHFCPNVPIILVGNKKDLRQDEHTRRELAKMKQEPVRSEEGRDMANRISAFGYLECSAKTKEGVREVFEMATRAGLQVRKNKRRRGCPIL 193

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Query:   31 MSAIRKKLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYVADIEVDNKQVELALWDTAGQEDYDRLRPLSYPDTDVILMCFSIDSTDSLENIVEKWYPEVKHFCPNVPIILVGNKKDLRNDERARHELAKMRQELVKYEDGLLTADKINAVKYLECSAKTKDGVREVFETATRAALSVKHKKKK--CNIL 603
            M+AIRKKLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENY+ADIEVD KQVELALWDTAGQEDYDRLRPLSYPDTDVILMCFSIDS DSLENI EKW PEVKHFCPNVPIILVGNKKDLR DE  R ELAKM+QE V+ E+G   A++I+A  YLECSAKTK+GVREVFE ATRA L V+  K++  C IL
Sbjct:    1 MAAIRKKLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYIADIEVDGKQVELALWDTAGQEDYDRLRPLSYPDTDVILMCFSIDSPDSLENIPEKWTPEVKHFCPNVPIILVGNKKDLRQDEHTRRELAKMKQEPVRSEEGRDMANRISAFGYLECSAKTKEGVREVFEMATRAGLQVRKNKRRRGCPIL 193

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BLAST of Rho-related GTP-binding protein vs. Ensembl Celegans
Match: rho-1 (Ras-like GTP-binding protein rhoA [Source:UniProtKB/Swiss-Prot;Acc:Q22038])

HSP 1 Score: 312.383 bits (799), Expect = 1.587e-108
Identity = 150/180 (83.33%), Postives = 161/180 (89.44%), Query Frame = 1

Query:   31 MSAIRKKLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYVADIEVDNKQVELALWDTAGQEDYDRLRPLSYPDTDVILMCFSIDSTDSLENIVEKWYPEVKHFCPNVPIILVGNKKDLRNDERARHELAKMRQELVKYEDGLLTADKINAVKYLECSAKTKDGVREVFETATRAALS 570
            M+AIRKKLVIVGDGACGKTCLLIVFSKDQFP+VYVPTVFENYVADIEVD KQVELALWDTAGQEDYDRLRPLSYPDTDVILMCFSIDS DSLENI EKW PEV+HFCPNVPIILVGNK+DLR+D +   ELAKM+QE VK E G   A++I A  YLECSAKTKDG+REVFE AT+AAL 
Sbjct:    1 MAAIRKKLVIVGDGACGKTCLLIVFSKDQFPDVYVPTVFENYVADIEVDGKQVELALWDTAGQEDYDRLRPLSYPDTDVILMCFSIDSPDSLENIPEKWTPEVRHFCPNVPIILVGNKRDLRSDPQTVRELAKMKQEPVKPEQGRAIAEQIGAFAYLECSAKTKDGIREVFEKATQAALQ 180

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BLAST of Rho-related GTP-binding protein vs. Ensembl Celegans
Match: ced-10 (Ras-related protein ced-10 [Source:UniProtKB/Swiss-Prot;Acc:Q03206])

HSP 1 Score: 223.016 bits (567), Expect = 3.214e-73
Identity = 107/193 (55.44%), Postives = 135/193 (69.95%), Query Frame = 1

Query:   31 MSAIRKKLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYVADIEVDNKQVELALWDTAGQEDYDRLRPLSYPDTDVILMCFSIDSTDSLENIVEKWYPEVKHFCPNVPIILVGNKKDLRNDERARHELAKMRQELVKYEDGLLTADKINAVKYLECSAKTKDGVREVFETATRAALSV--KHKKKKCNIL 603
            M AI  K V+VGDGA GKTCLLI ++ + FP  Y+PTVF+NY A++ VD + + L LWDTAGQEDYDRLRPLSYP TDV L+CF++++  S EN+  KWYPEV H CPN PIILVG K DLR D      L + R + V    G + A +I AVKYLECSA T+ G+++VF+ A RA L+   + KK KC +L
Sbjct:    1 MQAI--KCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDGRPINLGLWDTAGQEDYDRLRPLSYPQTDVFLVCFALNNPASFENVRAKWYPEVSHHCPNTPIILVGTKADLREDRDTVERLRERRLQPVSQTQGYVMAKEIKAVKYLECSALTQRGLKQVFDEAIRAVLTPPQRAKKSKCTVL 191

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BLAST of Rho-related GTP-binding protein vs. Ensembl Celegans
Match: mig-2 (Rac-like GTPase [Source:UniProtKB/TrEMBL;Acc:G5EBV3])

HSP 1 Score: 211.46 bits (537), Expect = 1.115e-68
Identity = 99/187 (52.94%), Postives = 126/187 (67.38%), Query Frame = 1

Query:   49 KLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYVADIEVDNKQVELALWDTAGQEDYDRLRPLSYPDTDVILMCFSIDSTDSLENIVEKWYPEVKHFCPNVPIILVGNKKDLRNDERARHELAKMRQELVKYEDGLLTADKINAVKYLECSAKTKDGVREVFETATRAALSVKHKKKK--CNIL 603
            K V+VGDG  GKTC+LI ++ D FP  YVPTVF+NY A + +D   V L LWDTAGQEDYDRLRPLSYP TDV ++CFS+ S  S +N+  KW PE++  CP+ P+ILVG K DLR++      L    +  +    G+  A KI AVKYLECSA T+ G+ +VFE A R+ L  K +KKK  CNI+
Sbjct:    9 KCVVVGDGTVGKTCMLISYTTDSFPVQYVPTVFDNYSAQMSLDGNVVNLGLWDTAGQEDYDRLRPLSYPQTDVFILCFSVVSPVSFDNVASKWIPEIRQHCPDAPVILVGTKLDLRDEAEPMRALQAEGKSPISKTQGMKMAQKIKAVKYLECSALTQQGLTQVFEDAVRSILHPKPQKKKKSCNIM 195

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BLAST of Rho-related GTP-binding protein vs. Ensembl Celegans
Match: cdc-42 (Cell division control protein 42 homolog [Source:UniProtKB/Swiss-Prot;Acc:Q05062])

HSP 1 Score: 202.216 bits (513), Expect = 3.391e-65
Identity = 99/187 (52.94%), Postives = 129/187 (68.98%), Query Frame = 1

Query:   49 KLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYVADIEVDNKQVELALWDTAGQEDYDRLRPLSYPDTDVILMCFSIDSTDSLENIVEKWYPEVKHFCPNVPIILVGNKKDLRNDERARHELAKMRQELVKYEDGLLTADKINAVKYLECSAKTKDGVREVFETATRAAL--SVKHKKKKCNIL 603
            K V+VGDGA GKTCLLI ++ ++FP  YVPTVF+NY   + +  +   L L+DTAGQEDYDRLRPLSYP TDV L+CFS+ +  S EN+ EKW PE+ H C   P +LVG + DLR+D     +LAK +Q+ V  + G   A ++ AVKY+ECSA T+ G++ VF+ A  AAL    + KKKKCNIL
Sbjct:    5 KCVVVGDGAVGKTCLLISYTTNKFPSEYVPTVFDNYAVTVMIGGEPYTLGLFDTAGQEDYDRLRPLSYPQTDVFLVCFSVVAPASFENVREKWVPEISHHCSKTPFLLVGTQVDLRDDPGMLEKLAKNKQKPVSTDVGEKLAKELKAVKYVECSALTQKGLKNVFDEAILAALDPPQQEKKKKCNIL 191

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BLAST of Rho-related GTP-binding protein vs. Ensembl Celegans
Match: rac-2 (Ras-related protein rac-2 [Source:UniProtKB/Swiss-Prot;Acc:Q94124])

HSP 1 Score: 201.06 bits (510), Expect = 1.169e-64
Identity = 96/197 (48.73%), Postives = 130/197 (65.99%), Query Frame = 1

Query:   31 MSAIRKKLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYVADIEVDNKQVELALWDTAGQEDYDRLRPLSYPDTDVILMCFSIDSTDSLENIVEKWYPEVKHFCPNVPIILVGNKKDLRNDERARHELAKMRQELVKYEDGLLTADKINAVKYLECSAKTKDGVREVFETATRAALS------VKHKKKKCNIL 603
            M AI  K V+VGDGA GKTCLL+ ++ + FP  Y+ TVF+ Y  ++ VD + + L+LWDTAGQ+DYD+ R LS+P TDV L+CF++++  S EN+  KWYPEV H CPN PIILVG K DLR D      L + R + V +  G + A +I AVKYLECSA T+ G+++VF+ A R  L+       + KK  C +L
Sbjct:    1 MQAI--KCVVVGDGAVGKTCLLLSYTTNAFPGEYILTVFDTYSTNVMVDGRPINLSLWDTAGQDDYDQFRHLSFPQTDVFLVCFALNNPASFENVRAKWYPEVSHHCPNTPIILVGTKADLREDRDTIERLRERRLQPVSHTQGYVMAKEIKAVKYLECSALTQIGLKQVFDEAIRTGLTPPQTPQTRAKKSNCTVL 195

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BLAST of Rho-related GTP-binding protein vs. Ensembl Fly
Match: Rho1 (gene:FBgn0014020 transcript:FBtr0087212)

HSP 1 Score: 323.553 bits (828), Expect = 7.898e-113
Identity = 158/192 (82.29%), Postives = 171/192 (89.06%), Query Frame = 1

Query:   31 MSAIRKKLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYVADIEVDNKQVELALWDTAGQEDYDRLRPLSYPDTDVILMCFSIDSTDSLENIVEKWYPEVKHFCPNVPIILVGNKKDLRNDERARHELAKMRQELVKYEDGLLTADKINAVKYLECSAKTKDGVREVFETATRAALSVKHKKK-KCNIL 603
            M+ IRKKLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYVADIEVD KQVELALWDTAGQEDYDRLRPLSYPDTDVILMCFS+DS DSLENI EKW PEVKHFCPNVPIILVGNKKDLRND     +LAKM+QE VK ++G   A+KINA  YLECSAK+K+GVR+VFETATRAAL VK +KK +C +L
Sbjct:    1 MTTIRKKLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYVADIEVDGKQVELALWDTAGQEDYDRLRPLSYPDTDVILMCFSVDSPDSLENIPEKWTPEVKHFCPNVPIILVGNKKDLRNDPNTIRDLAKMKQEPVKPQEGRAMAEKINAFAYLECSAKSKEGVRDVFETATRAALQVKKRKKTRCLLL 192

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BLAST of Rho-related GTP-binding protein vs. Ensembl Fly
Match: Rho1 (gene:FBgn0014020 transcript:FBtr0087213)

HSP 1 Score: 323.553 bits (828), Expect = 7.898e-113
Identity = 158/192 (82.29%), Postives = 171/192 (89.06%), Query Frame = 1

Query:   31 MSAIRKKLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYVADIEVDNKQVELALWDTAGQEDYDRLRPLSYPDTDVILMCFSIDSTDSLENIVEKWYPEVKHFCPNVPIILVGNKKDLRNDERARHELAKMRQELVKYEDGLLTADKINAVKYLECSAKTKDGVREVFETATRAALSVKHKKK-KCNIL 603
            M+ IRKKLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYVADIEVD KQVELALWDTAGQEDYDRLRPLSYPDTDVILMCFS+DS DSLENI EKW PEVKHFCPNVPIILVGNKKDLRND     +LAKM+QE VK ++G   A+KINA  YLECSAK+K+GVR+VFETATRAAL VK +KK +C +L
Sbjct:    1 MTTIRKKLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYVADIEVDGKQVELALWDTAGQEDYDRLRPLSYPDTDVILMCFSVDSPDSLENIPEKWTPEVKHFCPNVPIILVGNKKDLRNDPNTIRDLAKMKQEPVKPQEGRAMAEKINAFAYLECSAKSKEGVRDVFETATRAALQVKKRKKTRCLLL 192

[Close]

BLAST of Rho-related GTP-binding protein vs. Ensembl Fly
Match: Rho1 (gene:FBgn0014020 transcript:FBtr0087216)

HSP 1 Score: 323.553 bits (828), Expect = 7.898e-113
Identity = 158/192 (82.29%), Postives = 171/192 (89.06%), Query Frame = 1

Query:   31 MSAIRKKLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYVADIEVDNKQVELALWDTAGQEDYDRLRPLSYPDTDVILMCFSIDSTDSLENIVEKWYPEVKHFCPNVPIILVGNKKDLRNDERARHELAKMRQELVKYEDGLLTADKINAVKYLECSAKTKDGVREVFETATRAALSVKHKKK-KCNIL 603
            M+ IRKKLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYVADIEVD KQVELALWDTAGQEDYDRLRPLSYPDTDVILMCFS+DS DSLENI EKW PEVKHFCPNVPIILVGNKKDLRND     +LAKM+QE VK ++G   A+KINA  YLECSAK+K+GVR+VFETATRAAL VK +KK +C +L
Sbjct:    1 MTTIRKKLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYVADIEVDGKQVELALWDTAGQEDYDRLRPLSYPDTDVILMCFSVDSPDSLENIPEKWTPEVKHFCPNVPIILVGNKKDLRNDPNTIRDLAKMKQEPVKPQEGRAMAEKINAFAYLECSAKSKEGVRDVFETATRAALQVKKRKKTRCLLL 192

[Close]

BLAST of Rho-related GTP-binding protein vs. Ensembl Fly
Match: Rho1 (gene:FBgn0014020 transcript:FBtr0087214)

HSP 1 Score: 323.553 bits (828), Expect = 7.898e-113
Identity = 158/192 (82.29%), Postives = 171/192 (89.06%), Query Frame = 1

Query:   31 MSAIRKKLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYVADIEVDNKQVELALWDTAGQEDYDRLRPLSYPDTDVILMCFSIDSTDSLENIVEKWYPEVKHFCPNVPIILVGNKKDLRNDERARHELAKMRQELVKYEDGLLTADKINAVKYLECSAKTKDGVREVFETATRAALSVKHKKK-KCNIL 603
            M+ IRKKLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYVADIEVD KQVELALWDTAGQEDYDRLRPLSYPDTDVILMCFS+DS DSLENI EKW PEVKHFCPNVPIILVGNKKDLRND     +LAKM+QE VK ++G   A+KINA  YLECSAK+K+GVR+VFETATRAAL VK +KK +C +L
Sbjct:    1 MTTIRKKLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYVADIEVDGKQVELALWDTAGQEDYDRLRPLSYPDTDVILMCFSVDSPDSLENIPEKWTPEVKHFCPNVPIILVGNKKDLRNDPNTIRDLAKMKQEPVKPQEGRAMAEKINAFAYLECSAKSKEGVRDVFETATRAALQVKKRKKTRCLLL 192

[Close]

BLAST of Rho-related GTP-binding protein vs. Ensembl Fly
Match: Rho1 (gene:FBgn0014020 transcript:FBtr0087211)

HSP 1 Score: 323.553 bits (828), Expect = 7.898e-113
Identity = 158/192 (82.29%), Postives = 171/192 (89.06%), Query Frame = 1

Query:   31 MSAIRKKLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYVADIEVDNKQVELALWDTAGQEDYDRLRPLSYPDTDVILMCFSIDSTDSLENIVEKWYPEVKHFCPNVPIILVGNKKDLRNDERARHELAKMRQELVKYEDGLLTADKINAVKYLECSAKTKDGVREVFETATRAALSVKHKKK-KCNIL 603
            M+ IRKKLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYVADIEVD KQVELALWDTAGQEDYDRLRPLSYPDTDVILMCFS+DS DSLENI EKW PEVKHFCPNVPIILVGNKKDLRND     +LAKM+QE VK ++G   A+KINA  YLECSAK+K+GVR+VFETATRAAL VK +KK +C +L
Sbjct:    1 MTTIRKKLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYVADIEVDGKQVELALWDTAGQEDYDRLRPLSYPDTDVILMCFSVDSPDSLENIPEKWTPEVKHFCPNVPIILVGNKKDLRNDPNTIRDLAKMKQEPVKPQEGRAMAEKINAFAYLECSAKSKEGVRDVFETATRAALQVKKRKKTRCLLL 192

[Close]

BLAST of Rho-related GTP-binding protein vs. Ensembl Zebrafish
Match: rhoac (ras homolog gene family, member Ac [Source:NCBI gene;Acc:406659])

HSP 1 Score: 331.643 bits (849), Expect = 7.006e-116
Identity = 162/191 (84.82%), Postives = 170/191 (89.01%), Query Frame = 1

Query:   31 MSAIRKKLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYVADIEVDNKQVELALWDTAGQEDYDRLRPLSYPDTDVILMCFSIDSTDSLENIVEKWYPEVKHFCPNVPIILVGNKKDLRNDERARHELAKMRQELVKYEDGLLTADKINAVKYLECSAKTKDGVREVFETATRAALSVKHKKKKCNIL 603
            M+AIRKKLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYVADIEVD+KQVELALWDTAGQEDYDRLRPLSYPDTDVILMCFSIDS DSLENI EKW PEVKHFCPNVPIILVGNKKDLRNDE  R ELAKM+QE VK E+G   A++INA  YLECSAKTKDGVREVFE ATRAAL  + + KK   L
Sbjct:    1 MAAIRKKLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYVADIEVDSKQVELALWDTAGQEDYDRLRPLSYPDTDVILMCFSIDSPDSLENIPEKWTPEVKHFCPNVPIILVGNKKDLRNDEHTRRELAKMKQEPVKPEEGRDMANRINAFGYLECSAKTKDGVREVFEMATRAALQARKRGKKSGCL 191

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BLAST of Rho-related GTP-binding protein vs. Ensembl Zebrafish
Match: rhocb (ras homolog family member Cb [Source:NCBI gene;Acc:436718])

HSP 1 Score: 328.946 bits (842), Expect = 8.319e-115
Identity = 159/191 (83.25%), Postives = 171/191 (89.53%), Query Frame = 1

Query:   31 MSAIRKKLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYVADIEVDNKQVELALWDTAGQEDYDRLRPLSYPDTDVILMCFSIDSTDSLENIVEKWYPEVKHFCPNVPIILVGNKKDLRNDERARHELAKMRQELVKYEDGLLTADKINAVKYLECSAKTKDGVREVFETATRAALSVKHKKKKCNIL 603
            M+AIRKKLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENY+ADIEVD+KQVELALWDTAGQEDYDRLRPLSYPDTDVILMCFS+DS DSLENI EKW PEVKHFCPNVPIILVGNKKDLRNDE  R EL KM+QE VK E+G   A++I+A  YLECSAKTKDGVREVFE ATRAAL V+ +KK+   L
Sbjct:    1 MAAIRKKLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYIADIEVDSKQVELALWDTAGQEDYDRLRPLSYPDTDVILMCFSVDSPDSLENIPEKWTPEVKHFCPNVPIILVGNKKDLRNDEHTRRELIKMKQEPVKPEEGRDMANRISAFGYLECSAKTKDGVREVFEMATRAALQVRKRKKRSGCL 191

[Close]

BLAST of Rho-related GTP-binding protein vs. Ensembl Zebrafish
Match: rhoaa (ras homolog gene family, member Aa [Source:NCBI gene;Acc:406411])

HSP 1 Score: 328.946 bits (842), Expect = 8.319e-115
Identity = 162/193 (83.94%), Postives = 171/193 (88.60%), Query Frame = 1

Query:   31 MSAIRKKLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYVADIEVDNKQVELALWDTAGQEDYDRLRPLSYPDTDVILMCFSIDSTDSLENIVEKWYPEVKHFCPNVPIILVGNKKDLRNDERARHELAKMRQELVKYEDGLLTADKINAVKYLECSAKTKDGVREVFETATRAALSVKHKKKK--CNIL 603
            M+AIRKKLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYVADIEVD+KQVELALWDTAGQEDYDRLRPLSYPDTDVILMCFSIDS DSLENI EKW PEVKHFCPNVPIILVGNKKDLRNDE  R EL KM+QE VK E+G   A++INA  YLECSAKTK+GVREVFE ATRAAL  K + KK  C +L
Sbjct:    1 MAAIRKKLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYVADIEVDSKQVELALWDTAGQEDYDRLRPLSYPDTDVILMCFSIDSPDSLENIPEKWTPEVKHFCPNVPIILVGNKKDLRNDEHTRRELQKMKQEPVKPEEGRDMANRINAFGYLECSAKTKEGVREVFEMATRAALQAKKRGKKNACALL 193

[Close]

Query:   31 MSAIRKKLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYVADIEVDNKQVELALWDTAGQEDYDRLRPLSYPDTDVILMCFSIDSTDSLENIVEKWYPEVKHFCPNVPIILVGNKKDLRNDERARHELAKMRQELVKYEDGLLTADKINAVKYLECSAKTKDGVREVFETATRAALSVKHKKKK--CNIL 603
            M+AIRKKLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYVADIEVD+KQVELALWDTAGQEDYDRLRPLSYPDTDVILMCFSIDS DSLENI EKW PEVKHFCPNVPIILVGNKKDLRNDE  R EL KM+QE VK E+G   A++INA  YLECSAKTK+GVREVFE ATRAAL  K + KK  C +L
Sbjct:    1 MAAIRKKLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYVADIEVDSKQVELALWDTAGQEDYDRLRPLSYPDTDVILMCFSIDSPDSLENIPEKWTPEVKHFCPNVPIILVGNKKDLRNDEHTRRELQKMKQEPVKPEEGRDMANRINAFGYLECSAKTKEGVREVFEMATRAALQAKKRGKKNACALL 193

[Close]

Query:   31 MSAIRKKLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYVADIEVDNKQVELALWDTAGQEDYDRLRPLSYPDTDVILMCFSIDSTDSLENIVEKWYPEVKHFCPNVPIILVGNKKDLRNDERARHELAKMRQELVKYEDGLLTADKINAVKYLECSAKTKDGVREVFETATRAALSVKHKKKKCNIL 603
            M+AIRKKLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENY+ADIEVD+KQVELALWDTAGQEDYDRLRPLSYPDTDVILMCFS+DS DSLENI EKW PEVKHFCPNVPIILVGNKKDLRNDE  R EL KM+QE VK E+G   A++I+A  YLECSAKTKDGVREVFE ATRAAL V+ +KK+   L
Sbjct:    1 MAAIRKKLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYIADIEVDSKQVELALWDTAGQEDYDRLRPLSYPDTDVILMCFSVDSPDSLENIPEKWTPEVKHFCPNVPIILVGNKKDLRNDEHTRRELIKMKQEPVKPEEGRDMANRISAFGYLECSAKTKDGVREVFEMATRAALQVRKRKKRSGCL 191

[Close]

BLAST of Rho-related GTP-binding protein vs. Ensembl Xenopus
Match: cnn3 (calponin 3, acidic [Source:Xenbase;Acc:XB-GENE-951266])

HSP 1 Score: 335.109 bits (858), Expect = 3.948e-117
Identity = 166/193 (86.01%), Postives = 174/193 (90.16%), Query Frame = 1

Query:   31 MSAIRKKLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYVADIEVDNKQVELALWDTAGQEDYDRLRPLSYPDTDVILMCFSIDSTDSLENIVEKWYPEVKHFCPNVPIILVGNKKDLRNDERARHELAKMRQELVKYEDGLLTADKINAVKYLECSAKTKDGVREVFETATRAALSV-KHKKK-KCNIL 603
            M+AIRKKLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENY+ADIEVD KQVELALWDTAGQEDYDRLRPLSYPDTDVILMCFSIDS DSLENI EKW PEVKHFCPNVPIILVGNKKDLRNDE  R EL KM+QE VK EDG   A++INA  YLECSAKTKDGVREVFE ATRAAL V KH+KK +C+IL
Sbjct:    1 MAAIRKKLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYIADIEVDGKQVELALWDTAGQEDYDRLRPLSYPDTDVILMCFSIDSPDSLENIPEKWTPEVKHFCPNVPIILVGNKKDLRNDEHTRRELTKMKQEPVKPEDGREMANRINAFGYLECSAKTKDGVREVFEMATRAALQVRKHRKKQRCSIL 193

[Close]

BLAST of Rho-related GTP-binding protein vs. Ensembl Xenopus
Match: plek (pleckstrin [Source:Xenbase;Acc:XB-GENE-484214])

HSP 1 Score: 328.561 bits (841), Expect = 1.314e-114
Identity = 159/190 (83.68%), Postives = 169/190 (88.95%), Query Frame = 1

Query:   31 MSAIRKKLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYVADIEVDNKQVELALWDTAGQEDYDRLRPLSYPDTDVILMCFSIDSTDSLENIVEKWYPEVKHFCPNVPIILVGNKKDLRNDERARHELAKMRQELVKYEDGLLTADKINAVKYLECSAKTKDGVREVFETATRAALSVKHKKKKCNI 600
            M+AIRKKLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYVADIEVD+KQVELALWDTAGQEDYDRLRPLSYPDTDVILMCFSIDS DSLENI EKW PEVKHFCPNVPIILVGNKKDLRNDE  R EL KM+QE VK E+G   A++I+A  Y+ECSAKTKDGVREVFE ATRAAL  +  KKK  +
Sbjct:    1 MAAIRKKLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYVADIEVDSKQVELALWDTAGQEDYDRLRPLSYPDTDVILMCFSIDSPDSLENIPEKWTPEVKHFCPNVPIILVGNKKDLRNDEHTRRELTKMKQEPVKPEEGRDMANRISAYGYMECSAKTKDGVREVFELATRAALQARRGKKKTTV 190

[Close]

BLAST of Rho-related GTP-binding protein vs. Ensembl Xenopus
Match: plek (pleckstrin [Source:Xenbase;Acc:XB-GENE-484214])

HSP 1 Score: 328.176 bits (840), Expect = 2.695e-114
Identity = 160/191 (83.77%), Postives = 169/191 (88.48%), Query Frame = 1

Query:   31 MSAIRKKLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYVADIEVDNKQVELALWDTAGQEDYDRLRPLSYPDTDVILMCFSIDSTDSLENIVEKWYPEVKHFCPNVPIILVGNKKDLRNDERARHELAKMRQELVKYEDGLLTADKINAVKYLECSAKTKDGVREVFETATRAALSVKHKKKKCNIL 603
            M+AIRKKLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYVADIEVD+KQVELALWDTAGQEDYDRLRPLSYPDTDVILMCFSIDS DSLENI EKW PEVKHFCPNVPIILVGNKKDLRNDE  R EL KM+QE VK E+G   A++I+A  Y+ECSAKTKDGVREVFE ATRAAL  +  KKK   L
Sbjct:    1 MAAIRKKLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYVADIEVDSKQVELALWDTAGQEDYDRLRPLSYPDTDVILMCFSIDSPDSLENIPEKWTPEVKHFCPNVPIILVGNKKDLRNDEHTRRELTKMKQEPVKPEEGRDMANRISAYGYMECSAKTKDGVREVFELATRAALQARRGKKKTTCL 191

[Close]

BLAST of Rho-related GTP-binding protein vs. Ensembl Xenopus
Match: nsd3 (nuclear receptor binding SET domain protein 3 [Source:Xenbase;Acc:XB-GENE-5992933])

HSP 1 Score: 326.25 bits (835), Expect = 1.570e-113
Identity = 157/187 (83.96%), Postives = 168/187 (89.84%), Query Frame = 1

Query:   31 MSAIRKKLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYVADIEVDNKQVELALWDTAGQEDYDRLRPLSYPDTDVILMCFSIDSTDSLENIVEKWYPEVKHFCPNVPIILVGNKKDLRNDERARHELAKMRQELVKYEDGLLTADKINAVKYLECSAKTKDGVREVFETATRAALSVKHKKKK 591
            M+AIRKKLVIVGDGACGKTCLLI+FSKDQFPEVYVPTVFENYVADIEVD+KQVELALWDTAGQEDYDRLRPLSYPDTDVILMCFSIDS DSLENI EKW PEVKHFCPNVPIILVGNKKDLRNDE  R ELAKM+QE V+ E+G   A++I+A  YLECSAKT DGVREVFE ATRAAL  K  +K+
Sbjct:    1 MAAIRKKLVIVGDGACGKTCLLIMFSKDQFPEVYVPTVFENYVADIEVDSKQVELALWDTAGQEDYDRLRPLSYPDTDVILMCFSIDSPDSLENIPEKWTPEVKHFCPNVPIILVGNKKDLRNDEHTRRELAKMKQEPVRAEEGRDMANRISAFGYLECSAKTNDGVREVFEMATRAALQAKRGRKR 187

[Close]

BLAST of Rho-related GTP-binding protein vs. Ensembl Xenopus
Match: man1a2 (mannosidase, alpha, class 1A, member 2 [Source:Xenbase;Acc:XB-GENE-1010312])

HSP 1 Score: 322.783 bits (826), Expect = 3.388e-112
Identity = 155/185 (83.78%), Postives = 168/185 (90.81%), Query Frame = 1

Query:   31 MSAIRKKLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYVADIEVDNKQVELALWDTAGQEDYDRLRPLSYPDTDVILMCFSIDSTDSLENIVEKWYPEVKHFCPNVPIILVGNKKDLRNDERARHELAKMRQELVKYEDGLLTADKINAVKYLECSAKTKDGVREVFETATRAALSVKHKK 585
            M+AIRKKLV+VGDGACGKTCLLIVFSKD+FPEVYVPTVFENYVADIEVD KQVELALWDTAGQEDYDRLRPLSYPDTDVILMCFS+DS DSLENI EKW PEVKHFCP+VPIILV NKKDLRNDE  R+ELA+M+QE V+ EDG   A +INA +YLECSAKTK+GVREVFETATRAAL  KH +
Sbjct:    1 MAAIRKKLVVVGDGACGKTCLLIVFSKDEFPEVYVPTVFENYVADIEVDVKQVELALWDTAGQEDYDRLRPLSYPDTDVILMCFSVDSPDSLENIPEKWVPEVKHFCPSVPIILVANKKDLRNDEHVRNELARMKQEPVRTEDGRAMAVRINAFEYLECSAKTKEGVREVFETATRAALQKKHGR 185

[Close]

BLAST of Rho-related GTP-binding protein vs. Ensembl Mouse
Match: Rhoa (ras homolog family member A [Source:MGI Symbol;Acc:MGI:1096342])

HSP 1 Score: 329.717 bits (844), Expect = 3.950e-115
Identity = 161/191 (84.29%), Postives = 168/191 (87.96%), Query Frame = 1

Query:   31 MSAIRKKLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYVADIEVDNKQVELALWDTAGQEDYDRLRPLSYPDTDVILMCFSIDSTDSLENIVEKWYPEVKHFCPNVPIILVGNKKDLRNDERARHELAKMRQELVKYEDGLLTADKINAVKYLECSAKTKDGVREVFETATRAALSVKHKKKKCNIL 603
            M+AIRKKLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYVADIEVD KQVELALWDTAGQEDYDRLRPLSYPDTDVILMCFSIDS DSLENI EKW PEVKHFCPNVPIILVGNKKDLRNDE  R ELAKM+QE VK E+G   A++I A  Y+ECSAKTKDGVREVFE ATRAAL  +  KKK   L
Sbjct:    1 MAAIRKKLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYVADIEVDGKQVELALWDTAGQEDYDRLRPLSYPDTDVILMCFSIDSPDSLENIPEKWTPEVKHFCPNVPIILVGNKKDLRNDEHTRRELAKMKQEPVKPEEGRDMANRIGAFGYMECSAKTKDGVREVFEMATRAALQARRGKKKSGCL 191

[Close]

BLAST of Rho-related GTP-binding protein vs. Ensembl Mouse
Match: Rhoc (ras homolog family member C [Source:MGI Symbol;Acc:MGI:106028])

HSP 1 Score: 324.709 bits (831), Expect = 4.673e-113
Identity = 158/193 (81.87%), Postives = 170/193 (88.08%), Query Frame = 1

Query:   31 MSAIRKKLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYVADIEVDNKQVELALWDTAGQEDYDRLRPLSYPDTDVILMCFSIDSTDSLENIVEKWYPEVKHFCPNVPIILVGNKKDLRNDERARHELAKMRQELVKYEDGLLTADKINAVKYLECSAKTKDGVREVFETATRAALSVKHKKKK--CNIL 603
            M+AIRKKLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENY+ADIEVD KQVELALWDTAGQEDYDRLRPLSYPDTDVILMCFSIDS DSLENI EKW PEVKHFCPNVPIILVGNKKDLR DE  R ELAKM+QE V+ E+G   A++I+A  YLECSAKTK+GVREVFE ATRA L V+  K++  C IL
Sbjct:    1 MAAIRKKLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYIADIEVDGKQVELALWDTAGQEDYDRLRPLSYPDTDVILMCFSIDSPDSLENIPEKWTPEVKHFCPNVPIILVGNKKDLRQDEHTRRELAKMKQEPVRSEEGRDMANRISAFGYLECSAKTKEGVREVFEMATRAGLQVRKNKRRRGCPIL 193

[Close]

Query:   31 MSAIRKKLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYVADIEVDNKQVELALWDTAGQEDYDRLRPLSYPDTDVILMCFSIDSTDSLENIVEKWYPEVKHFCPNVPIILVGNKKDLRNDERARHELAKMRQELVKYEDGLLTADKINAVKYLECSAKTKDGVREVFETATRAALSVKHKKKK--CNIL 603
            M+AIRKKLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENY+ADIEVD KQVELALWDTAGQEDYDRLRPLSYPDTDVILMCFSIDS DSLENI EKW PEVKHFCPNVPIILVGNKKDLR DE  R ELAKM+QE V+ E+G   A++I+A  YLECSAKTK+GVREVFE ATRA L V+  K++  C IL
Sbjct:    1 MAAIRKKLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYIADIEVDGKQVELALWDTAGQEDYDRLRPLSYPDTDVILMCFSIDSPDSLENIPEKWTPEVKHFCPNVPIILVGNKKDLRQDEHTRRELAKMKQEPVRSEEGRDMANRISAFGYLECSAKTKEGVREVFEMATRAGLQVRKNKRRRGCPIL 193

[Close]

Query:   31 MSAIRKKLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYVADIEVDNKQVELALWDTAGQEDYDRLRPLSYPDTDVILMCFSIDSTDSLENIVEKWYPEVKHFCPNVPIILVGNKKDLRNDERARHELAKMRQELVKYEDGLLTADKINAVKYLECSAKTKDGVREVFETATRAALSVKHKKKK--CNIL 603
            M+AIRKKLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENY+ADIEVD KQVELALWDTAGQEDYDRLRPLSYPDTDVILMCFSIDS DSLENI EKW PEVKHFCPNVPIILVGNKKDLR DE  R ELAKM+QE V+ E+G   A++I+A  YLECSAKTK+GVREVFE ATRA L V+  K++  C IL
Sbjct:    1 MAAIRKKLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYIADIEVDGKQVELALWDTAGQEDYDRLRPLSYPDTDVILMCFSIDSPDSLENIPEKWTPEVKHFCPNVPIILVGNKKDLRQDEHTRRELAKMKQEPVRSEEGRDMANRISAFGYLECSAKTKEGVREVFEMATRAGLQVRKNKRRRGCPIL 193

[Close]

BLAST of Rho-related GTP-binding protein vs. Ensembl Mouse
Match: Rhob (ras homolog family member B [Source:MGI Symbol;Acc:MGI:107949])

HSP 1 Score: 314.309 bits (804), Expect = 5.572e-109
Identity = 151/186 (81.18%), Postives = 165/186 (88.71%), Query Frame = 1

Query:   31 MSAIRKKLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYVADIEVDNKQVELALWDTAGQEDYDRLRPLSYPDTDVILMCFSIDSTDSLENIVEKWYPEVKHFCPNVPIILVGNKKDLRNDERARHELAKMRQELVKYEDGLLTADKINAVKYLECSAKTKDGVREVFETATRAALSVKHKKK 588
            M+AIRKKLV+VGDGACGKTCLLIVFSKD+FPEVYVPTVFENYVADIEVD KQVELALWDTAGQEDYDRLRPLSYPDTDVILMCFS+DS DSLENI EKW PEVKHFCPNVPIILV NKKDLR+DE  R ELA+M+QE V+ +DG   A +I A  YLECSAKTK+GVREVFETATRAAL  ++  +
Sbjct:    1 MAAIRKKLVVVGDGACGKTCLLIVFSKDEFPEVYVPTVFENYVADIEVDGKQVELALWDTAGQEDYDRLRPLSYPDTDVILMCFSVDSPDSLENIPEKWVPEVKHFCPNVPIILVANKKDLRSDEHVRTELARMKQEPVRTDDGRAMAVRIQAYDYLECSAKTKEGVREVFETATRAALQKRYGSQ 186

[Close]

BLAST of Rho-related GTP-binding protein vs. UniProt/SwissProt
Match: sp|Q7T2E8|RHOAC_DANRE (Rho-related GTP-binding protein RhoA-C OS=Danio rerio OX=7955 GN=rhoac PE=1 SV=1)

HSP 1 Score: 331.643 bits (849), Expect = 5.289e-115
Identity = 162/191 (84.82%), Postives = 170/191 (89.01%), Query Frame = 1

Query:   31 MSAIRKKLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYVADIEVDNKQVELALWDTAGQEDYDRLRPLSYPDTDVILMCFSIDSTDSLENIVEKWYPEVKHFCPNVPIILVGNKKDLRNDERARHELAKMRQELVKYEDGLLTADKINAVKYLECSAKTKDGVREVFETATRAALSVKHKKKKCNIL 603
            M+AIRKKLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYVADIEVD+KQVELALWDTAGQEDYDRLRPLSYPDTDVILMCFSIDS DSLENI EKW PEVKHFCPNVPIILVGNKKDLRNDE  R ELAKM+QE VK E+G   A++INA  YLECSAKTKDGVREVFE ATRAAL  + + KK   L
Sbjct:    1 MAAIRKKLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYVADIEVDSKQVELALWDTAGQEDYDRLRPLSYPDTDVILMCFSIDSPDSLENIPEKWTPEVKHFCPNVPIILVGNKKDLRNDEHTRRELAKMKQEPVKPEEGRDMANRINAFGYLECSAKTKDGVREVFEMATRAALQARKRGKKSGCL 191

[Close]

BLAST of Rho-related GTP-binding protein vs. UniProt/SwissProt
Match: sp|P61589|RHOA_RAT (Transforming protein RhoA OS=Rattus norvegicus OX=10116 GN=Rhoa PE=1 SV=1)

HSP 1 Score: 329.717 bits (844), Expect = 2.763e-114
Identity = 161/191 (84.29%), Postives = 168/191 (87.96%), Query Frame = 1

Query:   31 MSAIRKKLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYVADIEVDNKQVELALWDTAGQEDYDRLRPLSYPDTDVILMCFSIDSTDSLENIVEKWYPEVKHFCPNVPIILVGNKKDLRNDERARHELAKMRQELVKYEDGLLTADKINAVKYLECSAKTKDGVREVFETATRAALSVKHKKKKCNIL 603
            M+AIRKKLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYVADIEVD KQVELALWDTAGQEDYDRLRPLSYPDTDVILMCFSIDS DSLENI EKW PEVKHFCPNVPIILVGNKKDLRNDE  R ELAKM+QE VK E+G   A++I A  Y+ECSAKTKDGVREVFE ATRAAL  +  KKK   L
Sbjct:    1 MAAIRKKLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYVADIEVDGKQVELALWDTAGQEDYDRLRPLSYPDTDVILMCFSIDSPDSLENIPEKWTPEVKHFCPNVPIILVGNKKDLRNDEHTRRELAKMKQEPVKPEEGRDMANRIGAFGYMECSAKTKDGVREVFEMATRAALQARRGKKKSGCL 191

[Close]

BLAST of Rho-related GTP-binding protein vs. UniProt/SwissProt
Match: sp|Q9QUI0|RHOA_MOUSE (Transforming protein RhoA OS=Mus musculus OX=10090 GN=Rhoa PE=1 SV=1)

HSP 1 Score: 329.717 bits (844), Expect = 2.763e-114
Identity = 161/191 (84.29%), Postives = 168/191 (87.96%), Query Frame = 1

Query:   31 MSAIRKKLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYVADIEVDNKQVELALWDTAGQEDYDRLRPLSYPDTDVILMCFSIDSTDSLENIVEKWYPEVKHFCPNVPIILVGNKKDLRNDERARHELAKMRQELVKYEDGLLTADKINAVKYLECSAKTKDGVREVFETATRAALSVKHKKKKCNIL 603
            M+AIRKKLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYVADIEVD KQVELALWDTAGQEDYDRLRPLSYPDTDVILMCFSIDS DSLENI EKW PEVKHFCPNVPIILVGNKKDLRNDE  R ELAKM+QE VK E+G   A++I A  Y+ECSAKTKDGVREVFE ATRAAL  +  KKK   L
Sbjct:    1 MAAIRKKLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYVADIEVDGKQVELALWDTAGQEDYDRLRPLSYPDTDVILMCFSIDSPDSLENIPEKWTPEVKHFCPNVPIILVGNKKDLRNDEHTRRELAKMKQEPVKPEEGRDMANRIGAFGYMECSAKTKDGVREVFEMATRAALQARRGKKKSGCL 191

[Close]

BLAST of Rho-related GTP-binding protein vs. UniProt/SwissProt
Match: sp|Q5REY6|RHOA_PONAB (Transforming protein RhoA OS=Pongo abelii OX=9601 GN=RHOA PE=2 SV=2)

HSP 1 Score: 329.717 bits (844), Expect = 2.887e-114
Identity = 161/191 (84.29%), Postives = 168/191 (87.96%), Query Frame = 1

Query:   31 MSAIRKKLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYVADIEVDNKQVELALWDTAGQEDYDRLRPLSYPDTDVILMCFSIDSTDSLENIVEKWYPEVKHFCPNVPIILVGNKKDLRNDERARHELAKMRQELVKYEDGLLTADKINAVKYLECSAKTKDGVREVFETATRAALSVKHKKKKCNIL 603
            M+AIRKKLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYVADIEVD KQVELALWDTAGQEDYDRLRPLSYPDTDVILMCFSIDS DSLENI EKW PEVKHFCPNVPIILVGNKKDLRNDE  R ELAKM+QE VK E+G   A++I A  Y+ECSAKTKDGVREVFE ATRAAL  +  KKK   L
Sbjct:    1 MAAIRKKLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYVADIEVDGKQVELALWDTAGQEDYDRLRPLSYPDTDVILMCFSIDSPDSLENIPEKWTPEVKHFCPNVPIILVGNKKDLRNDEHTRRELAKMKQEPVKPEEGRDMANRIGAFGYMECSAKTKDGVREVFEMATRAALQARRGKKKSGCL 191

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BLAST of Rho-related GTP-binding protein vs. UniProt/SwissProt
Match: sp|P61586|RHOA_HUMAN (Transforming protein RhoA OS=Homo sapiens OX=9606 GN=RHOA PE=1 SV=1)

HSP 1 Score: 329.717 bits (844), Expect = 2.887e-114
Identity = 161/191 (84.29%), Postives = 168/191 (87.96%), Query Frame = 1

Query:   31 MSAIRKKLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYVADIEVDNKQVELALWDTAGQEDYDRLRPLSYPDTDVILMCFSIDSTDSLENIVEKWYPEVKHFCPNVPIILVGNKKDLRNDERARHELAKMRQELVKYEDGLLTADKINAVKYLECSAKTKDGVREVFETATRAALSVKHKKKKCNIL 603
            M+AIRKKLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYVADIEVD KQVELALWDTAGQEDYDRLRPLSYPDTDVILMCFSIDS DSLENI EKW PEVKHFCPNVPIILVGNKKDLRNDE  R ELAKM+QE VK E+G   A++I A  Y+ECSAKTKDGVREVFE ATRAAL  +  KKK   L
Sbjct:    1 MAAIRKKLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYVADIEVDGKQVELALWDTAGQEDYDRLRPLSYPDTDVILMCFSIDSPDSLENIPEKWTPEVKHFCPNVPIILVGNKKDLRNDEHTRRELAKMKQEPVKPEEGRDMANRIGAFGYMECSAKTKDGVREVFEMATRAALQARRGKKKSGCL 191

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BLAST of Rho-related GTP-binding protein vs. TrEMBL
Match: F2W7E1 (Rho2 GTPase OS=Dugesia japonica OX=6161 PE=2 SV=1)

HSP 1 Score: 394.43 bits (1012), Expect = 2.641e-137
Identity = 191/191 (100.00%), Postives = 191/191 (100.00%), Query Frame = 1

Query:   31 MSAIRKKLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYVADIEVDNKQVELALWDTAGQEDYDRLRPLSYPDTDVILMCFSIDSTDSLENIVEKWYPEVKHFCPNVPIILVGNKKDLRNDERARHELAKMRQELVKYEDGLLTADKINAVKYLECSAKTKDGVREVFETATRAALSVKHKKKKCNIL 603
            MSAIRKKLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYVADIEVDNKQVELALWDTAGQEDYDRLRPLSYPDTDVILMCFSIDSTDSLENIVEKWYPEVKHFCPNVPIILVGNKKDLRNDERARHELAKMRQELVKYEDGLLTADKINAVKYLECSAKTKDGVREVFETATRAALSVKHKKKKCNIL
Sbjct:    1 MSAIRKKLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYVADIEVDNKQVELALWDTAGQEDYDRLRPLSYPDTDVILMCFSIDSTDSLENIVEKWYPEVKHFCPNVPIILVGNKKDLRNDERARHELAKMRQELVKYEDGLLTADKINAVKYLECSAKTKDGVREVFETATRAALSVKHKKKKCNIL 191

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BLAST of Rho-related GTP-binding protein vs. TrEMBL
Match: Q5DDX1 (Rho-related GTP-binding protein isoform 1 OS=Schistosoma japonicum OX=6182 GN=EWB00_007674 PE=2 SV=1)

HSP 1 Score: 355.14 bits (910), Expect = 9.677e-122
Identity = 170/192 (88.54%), Postives = 182/192 (94.79%), Query Frame = 1

Query:   31 MSAIRKKLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYVADIEVDNKQVELALWDTAGQEDYDRLRPLSYPDTDVILMCFSIDSTDSLENIVEKWYPEVKHFCPNVPIILVGNKKDLRNDERARHELAKMRQELVKYEDGLLTADKINAVKYLECSAKTKDGVREVFETATRAALSVKHKKKK-CNIL 603
            M+AIRKKLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYVADIEVD KQVELALWDTAGQEDYDRLRPLSYPDTDVILMCFSIDSTDSL+NI+EKWYPEV+HFCPNVPIILVGNK+DLRNDERA HELAK RQELVKYE+G L AD+INA  YLECSAKTK+GVR+VFETATRAALS KHK+KK C ++
Sbjct:    1 MAAIRKKLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYVADIEVDGKQVELALWDTAGQEDYDRLRPLSYPDTDVILMCFSIDSTDSLDNIIEKWYPEVEHFCPNVPIILVGNKQDLRNDERAHHELAKARQELVKYEEGRLMADRINAYVYLECSAKTKEGVRKVFETATRAALSTKHKRKKVCELI 192

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BLAST of Rho-related GTP-binding protein vs. TrEMBL
Match: A0A5J4NU18 (Ras protein family, member A OS=Paragonimus westermani OX=34504 GN=DEA37_0004941 PE=4 SV=1)

HSP 1 Score: 352.058 bits (902), Expect = 1.189e-120
Identity = 171/192 (89.06%), Postives = 180/192 (93.75%), Query Frame = 1

Query:   31 MSAIRKKLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYVADIEVDNKQVELALWDTAGQEDYDRLRPLSYPDTDVILMCFSIDSTDSLENIVEKWYPEVKHFCPNVPIILVGNKKDLRNDERARHELAKMRQELVKYEDGLLTADKINAVKYLECSAKTKDGVREVFETATRAALSVKHK-KKKCNIL 603
            M+AIRKKLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYVADIEVD KQVELALWDTAGQEDYDRLRPLSYPDTDVILMCFSIDSTDS +NIVEKWY EVKHFCPNVPIILVGNKKDLRNDERARHELAKMRQE+VK E+G + A++INA  YLECSAKTK+GVREVFETATRAALS K K KK CN+L
Sbjct:    1 MAAIRKKLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYVADIEVDGKQVELALWDTAGQEDYDRLRPLSYPDTDVILMCFSIDSTDSRDNIVEKWYSEVKHFCPNVPIILVGNKKDLRNDERARHELAKMRQEMVKPEEGRMLAERINAYAYLECSAKTKEGVREVFETATRAALSTKRKGKKGCNLL 192

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BLAST of Rho-related GTP-binding protein vs. TrEMBL
Match: A0A504YED6 (Ras GTP-binding protein Rho1 OS=Fasciola gigantica OX=46835 GN=FGIG_04030 PE=4 SV=1)

HSP 1 Score: 349.747 bits (896), Expect = 1.309e-119
Identity = 170/192 (88.54%), Postives = 180/192 (93.75%), Query Frame = 1

Query:   31 MSAIRKKLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYVADIEVDNKQVELALWDTAGQEDYDRLRPLSYPDTDVILMCFSIDSTDSLENIVEKWYPEVKHFCPNVPIILVGNKKDLRNDERARHELAKMRQELVKYEDGLLTADKINAVKYLECSAKTKDGVREVFETATRAALSVKHK-KKKCNIL 603
            M+AIRKKLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYVADIEVD KQVELALWDTAGQEDYDRLRPLSYPDTDVILMCFSIDSTDS +NI+EKWY EVKHFCPNVPIILVGNKKDLRNDERARHELAKMRQE+VK E+G L A++INA  YLECSAKTK+GVREVFETATRAALS K K KK C++L
Sbjct:    1 MAAIRKKLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYVADIEVDGKQVELALWDTAGQEDYDRLRPLSYPDTDVILMCFSIDSTDSRDNILEKWYSEVKHFCPNVPIILVGNKKDLRNDERARHELAKMRQEMVKPEEGRLMAERINAYAYLECSAKTKEGVREVFETATRAALSTKRKGKKPCDLL 192

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BLAST of Rho-related GTP-binding protein vs. TrEMBL
Match: A0A4E0R7E0 (Ras GTP-binding protein Rho1 OS=Fasciola hepatica OX=6192 GN=D915_004867 PE=4 SV=1)

HSP 1 Score: 349.747 bits (896), Expect = 1.309e-119
Identity = 170/192 (88.54%), Postives = 180/192 (93.75%), Query Frame = 1

Query:   31 MSAIRKKLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYVADIEVDNKQVELALWDTAGQEDYDRLRPLSYPDTDVILMCFSIDSTDSLENIVEKWYPEVKHFCPNVPIILVGNKKDLRNDERARHELAKMRQELVKYEDGLLTADKINAVKYLECSAKTKDGVREVFETATRAALSVKHK-KKKCNIL 603
            M+AIRKKLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYVADIEVD KQVELALWDTAGQEDYDRLRPLSYPDTDVILMCFSIDSTDS +NI+EKWY EVKHFCPNVPIILVGNKKDLRNDERARHELAKMRQE+VK E+G L A++INA  YLECSAKTK+GVREVFETATRAALS K K KK C++L
Sbjct:    1 MAAIRKKLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYVADIEVDGKQVELALWDTAGQEDYDRLRPLSYPDTDVILMCFSIDSTDSRDNILEKWYSEVKHFCPNVPIILVGNKKDLRNDERARHELAKMRQEMVKPEEGRLMAERINAYAYLECSAKTKEGVREVFETATRAALSTKRKGKKPCDLL 192

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BLAST of Rho-related GTP-binding protein vs. Ensembl Cavefish
Match: rhocb (rho-related GTP-binding protein RhoA-D [Source:NCBI gene;Acc:103031338])

HSP 1 Score: 330.487 bits (846), Expect = 1.763e-115
Identity = 160/191 (83.77%), Postives = 171/191 (89.53%), Query Frame = 1

Query:   31 MSAIRKKLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYVADIEVDNKQVELALWDTAGQEDYDRLRPLSYPDTDVILMCFSIDSTDSLENIVEKWYPEVKHFCPNVPIILVGNKKDLRNDERARHELAKMRQELVKYEDGLLTADKINAVKYLECSAKTKDGVREVFETATRAALSVKHKKKKCNIL 603
            M+AIRKKLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENY+ADIEVD KQVELALWDTAGQEDYDRLRPLSYPDTDVILMCFSIDS DSLENI EKW PEVKHFCPNVPIILVGNKKDLRNDE  R ELAKM+QE VK E+G   A++I+A  YLECSAKTK+GVREVFE ATRAAL V+ +KK+   L
Sbjct:    3 MAAIRKKLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYIADIEVDGKQVELALWDTAGQEDYDRLRPLSYPDTDVILMCFSIDSPDSLENIPEKWTPEVKHFCPNVPIILVGNKKDLRNDEHTRRELAKMKQEPVKPEEGRDMANRISAFGYLECSAKTKEGVREVFEMATRAALQVRKRKKRSGCL 193

[Close]

BLAST of Rho-related GTP-binding protein vs. Ensembl Cavefish
Match: rhocb (rho-related GTP-binding protein RhoA-D [Source:NCBI gene;Acc:103031338])

HSP 1 Score: 330.487 bits (846), Expect = 2.091e-115
Identity = 160/191 (83.77%), Postives = 171/191 (89.53%), Query Frame = 1

Query:   31 MSAIRKKLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYVADIEVDNKQVELALWDTAGQEDYDRLRPLSYPDTDVILMCFSIDSTDSLENIVEKWYPEVKHFCPNVPIILVGNKKDLRNDERARHELAKMRQELVKYEDGLLTADKINAVKYLECSAKTKDGVREVFETATRAALSVKHKKKKCNIL 603
            M+AIRKKLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENY+ADIEVD KQVELALWDTAGQEDYDRLRPLSYPDTDVILMCFSIDS DSLENI EKW PEVKHFCPNVPIILVGNKKDLRNDE  R ELAKM+QE VK E+G   A++I+A  YLECSAKTK+GVREVFE ATRAAL V+ +KK+   L
Sbjct:    1 MAAIRKKLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYIADIEVDGKQVELALWDTAGQEDYDRLRPLSYPDTDVILMCFSIDSPDSLENIPEKWTPEVKHFCPNVPIILVGNKKDLRNDEHTRRELAKMKQEPVKPEEGRDMANRISAFGYLECSAKTKEGVREVFEMATRAALQVRKRKKRSGCL 191

[Close]

BLAST of Rho-related GTP-binding protein vs. Ensembl Cavefish
Match: rhoca (rho-related GTP-binding protein RhoA-D-like [Source:NCBI gene;Acc:103035456])

HSP 1 Score: 330.102 bits (845), Expect = 2.333e-115
Identity = 160/191 (83.77%), Postives = 171/191 (89.53%), Query Frame = 1

Query:   31 MSAIRKKLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYVADIEVDNKQVELALWDTAGQEDYDRLRPLSYPDTDVILMCFSIDSTDSLENIVEKWYPEVKHFCPNVPIILVGNKKDLRNDERARHELAKMRQELVKYEDGLLTADKINAVKYLECSAKTKDGVREVFETATRAALSVKHKKKKCNIL 603
            M+AIRKKLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENY+ADIEVD KQVELALWDTAGQEDYDRLRPLSYPDTDVILMCFSIDS DSLENI EKW PEVKHFCPNVPIILVGNKKDLRNDE  R ELAKM+QE VK E+G   A++I+A  YLECSAKTK+GVREVFE ATRAAL V+ K+K+   L
Sbjct:    1 MAAIRKKLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYIADIEVDGKQVELALWDTAGQEDYDRLRPLSYPDTDVILMCFSIDSPDSLENIPEKWTPEVKHFCPNVPIILVGNKKDLRNDEHTRRELAKMKQEPVKPEEGRDMANRISAFGYLECSAKTKEGVREVFEMATRAALQVRKKRKRSGCL 191

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BLAST of Rho-related GTP-binding protein vs. Ensembl Cavefish
Match: rhoaa (rho-related GTP-binding protein RhoA-A [Source:NCBI gene;Acc:103028705])

HSP 1 Score: 330.102 bits (845), Expect = 2.547e-115
Identity = 163/193 (84.46%), Postives = 170/193 (88.08%), Query Frame = 1

Query:   31 MSAIRKKLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYVADIEVDNKQVELALWDTAGQEDYDRLRPLSYPDTDVILMCFSIDSTDSLENIVEKWYPEVKHFCPNVPIILVGNKKDLRNDERARHELAKMRQELVKYEDGLLTADKINAVKYLECSAKTKDGVREVFETATRAALSVKHKKKK--CNIL 603
            M+AIRKKLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYVADIEVD KQVELALWDTAGQEDYDRLRPLSYPDTDVILMCFSIDS DSLENI EKW PEVKHFCPNVPIILVGNKKDLRNDE  R ELAKM+QE VK E+G   A++I A  YLECSAKTKDGVREVFE ATRAAL  K + KK  C +L
Sbjct:    1 MAAIRKKLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYVADIEVDGKQVELALWDTAGQEDYDRLRPLSYPDTDVILMCFSIDSPDSLENIPEKWTPEVKHFCPNVPIILVGNKKDLRNDEHTRRELAKMKQEPVKAEEGRDMANRIYAAGYLECSAKTKDGVREVFEMATRAALQAKKRSKKNACALL 193

[Close]

BLAST of Rho-related GTP-binding protein vs. Ensembl Cavefish
Match: rhoab (rho-related GTP-binding protein RhoA-B [Source:NCBI gene;Acc:103027457])

HSP 1 Score: 329.331 bits (843), Expect = 5.481e-115
Identity = 162/193 (83.94%), Postives = 171/193 (88.60%), Query Frame = 1

Query:   31 MSAIRKKLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYVADIEVDNKQVELALWDTAGQEDYDRLRPLSYPDTDVILMCFSIDSTDSLENIVEKWYPEVKHFCPNVPIILVGNKKDLRNDERARHELAKMRQELVKYEDGLLTADKINAVKYLECSAKTKDGVREVFETATRAALSVKHKKK--KCNIL 603
            M+AIRKKLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYVADIEVD+KQVELALWDTAGQEDYDRLRPLSYPDTDVILMCFSIDS DSLENI EKW PEVKHFCPNVPIILVGNKKDLRNDE  R ELAKM+QE VK E+G   A++I A  Y+ECSAKTKDGVREVFE ATRAAL  +  KK  KC +L
Sbjct:    1 MAAIRKKLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYVADIEVDSKQVELALWDTAGQEDYDRLRPLSYPDTDVILMCFSIDSPDSLENIPEKWTPEVKHFCPNVPIILVGNKKDLRNDEHTRRELAKMKQEPVKAEEGRDMANRIGAFGYMECSAKTKDGVREVFEMATRAALQARRGKKSNKCLLL 193

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BLAST of Rho-related GTP-binding protein vs. Ensembl Sea Lamprey
Match: ENSPMAT00000004439.1 (pep scaffold:Pmarinus_7.0:GL476335:1598569:1600956:1 gene:ENSPMAG00000004041.1 transcript:ENSPMAT00000004439.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 328.176 bits (840), Expect = 2.820e-115
Identity = 160/193 (82.90%), Postives = 172/193 (89.12%), Query Frame = 1

Query:   31 MSAIRKKLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYVADIEVDNKQVELALWDTAGQEDYDRLRPLSYPDTDVILMCFSIDSTDSLENIVEKWYPEVKHFCPNVPIILVGNKKDLRNDERARHELAKMRQELVKYEDGLLTADKINAVKYLECSAKTKDGVREVFETATRAALSVKHKKKK--CNIL 603
            M+AIRKKLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYVADIEVD KQVELALWDTAGQEDYDRLRPLSYPDTDVILMCFSIDS DSLENI EKW PEVKHFCPNVPIILVGNKKDLRND+  + ELAKM+QE V+ E+G   A++INA  Y+ECSAKTKDGVREVFE ATRAAL V+ +KK   C +L
Sbjct:    1 MAAIRKKLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYVADIEVDGKQVELALWDTAGQEDYDRLRPLSYPDTDVILMCFSIDSPDSLENIPEKWTPEVKHFCPNVPIILVGNKKDLRNDDNTKRELAKMKQEPVRVEEGRDMANRINAFGYMECSAKTKDGVREVFEMATRAALQVRKRKKTGGCRLL 193

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BLAST of Rho-related GTP-binding protein vs. Ensembl Sea Lamprey
Match: ENSPMAT00000001838.1 (pep scaffold:Pmarinus_7.0:GL478831:173097:182385:-1 gene:ENSPMAG00000001664.1 transcript:ENSPMAT00000001838.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 327.405 bits (838), Expect = 6.563e-115
Identity = 159/184 (86.41%), Postives = 166/184 (90.22%), Query Frame = 1

Query:   31 MSAIRKKLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYVADIEVDNKQVELALWDTAGQEDYDRLRPLSYPDTDVILMCFSIDSTDSLENIVEKWYPEVKHFCPNVPIILVGNKKDLRNDERARHELAKMRQELVKYEDGLLTADKINAVKYLECSAKTKDGVREVFETATRAALSVKHK 582
            M+AIRKKLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYVADIEVD KQVELALWDTAGQEDYDRLRPLSYPDTDVILMCFSIDS DSLENI EKW PEVKHFCPNVPIILVGNKKDLRNDE  R ELAKM+QE VK E+G   A++INA  Y+ECSAKTKDGVREVFE ATRAAL +  K
Sbjct:    1 MAAIRKKLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYVADIEVDGKQVELALWDTAGQEDYDRLRPLSYPDTDVILMCFSIDSPDSLENIPEKWTPEVKHFCPNVPIILVGNKKDLRNDESTRRELAKMKQEPVKSEEGRDMANRINAFGYMECSAKTKDGVREVFEMATRAALQLTAK 184

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BLAST of Rho-related GTP-binding protein vs. Ensembl Sea Lamprey
Match: ENSPMAT00000002754.1 (pep scaffold:Pmarinus_7.0:GL476453:253767:255265:1 gene:ENSPMAG00000002511.1 transcript:ENSPMAT00000002754.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 297.745 bits (761), Expect = 4.043e-103
Identity = 141/192 (73.44%), Postives = 163/192 (84.90%), Query Frame = 1

Query:   43 RKKLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYVADIEVDNKQVELALWDTAGQEDYDRLRPLSYPDTDVILMCFSIDSTDSLENIVEKWYPEVKHFCPNVPIILVGNKKDLRNDERARHELAKMRQELVKYEDGLLTADKINAVKYLECSAKTKDGVREVFETATRAALSVKHKKK-----KCNIL 603
            RKKLV+VGDGACGKTCLL+VFSKD+FP+VYVPTVFE YVADIEVD +QVELALWDTAGQEDYDRLRPLSYPDTDVILMCFS+DS DSLEN+ EKW PEV+HFCPNVPI+LV NKKDLR DE    ELA++++E +K EDG   A +I A  Y+ECSA+TKDGVR VFETATRAA+  + K++     KCN+L
Sbjct:    7 RKKLVVVGDGACGKTCLLMVFSKDKFPDVYVPTVFETYVADIEVDGRQVELALWDTAGQEDYDRLRPLSYPDTDVILMCFSVDSPDSLENVPEKWVPEVQHFCPNVPIVLVANKKDLRGDESVLQELARIKREPLKPEDGRTMASRIQAFDYVECSAQTKDGVRLVFETATRAAIQKQSKRRGRSCFKCNLL 198

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BLAST of Rho-related GTP-binding protein vs. Ensembl Sea Lamprey
Match: ENSPMAT00000008827.1 (pep scaffold:Pmarinus_7.0:GL480655:11470:16574:-1 gene:ENSPMAG00000007986.1 transcript:ENSPMAT00000008827.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 277.33 bits (708), Expect = 3.105e-95
Identity = 147/199 (73.87%), Postives = 158/199 (79.40%), Query Frame = 1

Query:   31 MSAIRKKLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYVADIEVDNKQ-----VELALWDTAGQEDYDRLRPLSYPDTDVILMCFSIDSTDSLENIVEKWYPEVKHFCPNVPIILVGNKKDLRNDERARHELAKMRQELVKYEDGLLTADKI-NAVKYLECSAKTKDGVREVFETATRAALSVKHKKKK--CNIL 603
            M+AIRKKLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYVADIEVD KQ     VELALWDTAGQEDYDRLRPLSYPDTDVILMCFSIDS DSLENI EKW PEVKHFCPNVPIILVGNK+DLR+D+  R ELAKM+Q  V  +    T D I N V   +   ++   VREVFE ATRAAL V+  KK   C +L
Sbjct:    1 MAAIRKKLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYVADIEVDGKQSVVNQVELALWDTAGQEDYDRLRPLSYPDTDVILMCFSIDSPDSLENIPEKWTPEVKHFCPNVPIILVGNKRDLRHDDATRRELAKMKQNEVNEK----TLDVIQNDVSLFKRIRRSSTLVREVFELATRAALHVRTHKKNGFCRLL 195

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BLAST of Rho-related GTP-binding protein vs. Ensembl Sea Lamprey
Match: ENSPMAT00000006108.1 (pep scaffold:Pmarinus_7.0:GL480344:135:8553:-1 gene:ENSPMAG00000005525.1 transcript:ENSPMAT00000006108.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 262.692 bits (670), Expect = 3.401e-90
Identity = 126/136 (92.65%), Postives = 128/136 (94.12%), Query Frame = 1

Query:   31 MSAIRKKLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYVADIEVDNKQVELALWDTAGQEDYDRLRPLSYPDTDVILMCFSIDSTDSLENIVEKWYPEVKHFCPNVPIILVGNKKDLRNDERARHELAKMRQ 438
            M+AIRKKLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYVADIEVD KQVELALWDTAGQEDYDRLRPLSYPDTDVILMCFSIDS DSLENI EKW PEVKHFCPNVPIILVGNKKDLRNDE  R ELAK +Q
Sbjct:    1 MAAIRKKLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYVADIEVDGKQVELALWDTAGQEDYDRLRPLSYPDTDVILMCFSIDSPDSLENIPEKWTPEVKHFCPNVPIILVGNKKDLRNDENTRRELAKTKQ 136

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BLAST of Rho-related GTP-binding protein vs. Ensembl Yeast
Match: RHO1 (GTP-binding protein of the rho subfamily of Ras-like proteins; involved in establishment of cell polarity; regulates protein kinase C (Pkc1p) and the cell wall synthesizing enzyme 1,3-beta-glucan synthase (Fks1p and Gsc2p) [Source:SGD;Acc:S000006369])

HSP 1 Score: 267.7 bits (683), Expect = 2.109e-91
Identity = 129/183 (70.49%), Postives = 148/183 (80.87%), Query Frame = 1

Query:   34 SAIRKKLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYVADIEVDNKQVELALWDTAGQEDYDRLRPLSYPDTDVILMCFSIDSTDSLENIVEKWYPEVKHFCPNVPIILVGNKKDLRNDERARHELAKMRQELVKYEDGLLTADKINAVKYLECSAKTKDGVREVFETATRAALSVKHK 582
            ++IR+KLVIVGDGACGKTCLLIVFSK QFPEVYVPTVFENYVAD+EVD ++VELALWDTAGQEDYDRLRPLSYPD++V+L+CFSID  DSLEN+ EKW  EV HFC  VPIILVG K DLRND +   +L +  Q+ V  ++G   AD+I A  Y ECSAKT  GVREVFE ATRA+L  K K
Sbjct:    7 NSIRRKLVIVGDGACGKTCLLIVFSKGQFPEVYVPTVFENYVADVEVDGRRVELALWDTAGQEDYDRLRPLSYPDSNVVLICFSIDLPDSLENVQEKWIAEVLHFCQGVPIILVGCKVDLRNDPQTIEQLRQEGQQPVTSQEGQSVADQIGATGYYECSAKTGYGVREVFEAATRASLMGKSK 189

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BLAST of Rho-related GTP-binding protein vs. Ensembl Yeast
Match: CDC42 (Small rho-like GTPase; essential for establishment and maintenance of cell polarity; plays a role late in cell fusion via activation of key cell fusion regulator Fus2p; mutants have defects in the organization of actin and septins; human homolog CDC42 can complement yeast cdc42 mutant [Source:SGD;Acc:S000004219])

HSP 1 Score: 204.142 bits (518), Expect = 1.355e-66
Identity = 100/187 (53.48%), Postives = 129/187 (68.98%), Query Frame = 1

Query:   49 KLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYVADIEVDNKQVELALWDTAGQEDYDRLRPLSYPDTDVILMCFSIDSTDSLENIVEKWYPEVKHFCPNVPIILVGNKKDLRNDERARHELAKMRQELVKYEDGLLTADKINAVKYLECSAKTKDGVREVFETATRAAL--SVKHKKKKCNIL 603
            K V+VGDGA GKTCLLI ++ +QFP  YVPTVF+NY   + + ++   L L+DTAGQEDYDRLRPLSYP TDV L+CFS+ S  S EN+ EKW+PEV H CP VP ++VG + DLR+D+    +L + R   +  E G   A ++ AVKY+ECSA T+ G++ VF+ A  AAL   V  K KKC IL
Sbjct:    5 KCVVVGDGAVGKTCLLISYTTNQFPADYVPTVFDNYAVTVMIGDEPYTLGLFDTAGQEDYDRLRPLSYPSTDVFLVCFSVISPPSFENVKEKWFPEVHHHCPGVPCLVVGTQIDLRDDKVIIEKLQRQRLRPITSEQGSRLARELKAVKYVECSALTQRGLKNVFDEAIVAALEPPVIKKSKKCAIL 191

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BLAST of Rho-related GTP-binding protein vs. Ensembl Yeast
Match: RHO3 (Non-essential small GTPase of the Rho/Rac family of Ras-like proteins; involved in the establishment of cell polarity; GTPase activity positively regulated by the GTPase activating protein (GAP) Rgd1p [Source:SGD;Acc:S000001380])

HSP 1 Score: 201.83 bits (512), Expect = 3.683e-65
Identity = 101/199 (50.75%), Postives = 129/199 (64.82%), Query Frame = 1

Query:   40 IRKKLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYVADIEVDNKQVELALWDTAGQEDYDRLRPLSYPDTDVILMCFSIDSTDSLENIVEKWYPEVKHFCPNVPIILVGNKKDLRNDERARHELA--KMRQE-------------------LVKYEDGLLTADKINAVKYLECSAKTKDGVREVFETATRAALSV 573
            I +K+VI+GDGACGKT LL VF++  FPEVY PTVFENY+ DI VD+K + L+LWDTAGQE++DRLR LSY DT  I++CFSIDS DSLEN+  KW  E+   C  V ++LV  K DLRN+E   + +    ++Q+                   L+ YE+GL  A KI A++YLECSAK   GV E F  A R AL+ 
Sbjct:   15 IERKIVILGDGACGKTSLLNVFTRGYFPEVYEPTVFENYIHDIFVDSKHITLSLWDTAGQEEFDRLRSLSYSDTQCIMLCFSIDSRDSLENVQNKWVGEITDHCEGVKLVLVALKCDLRNNENESNAITPNNIQQDNSVSNDNGNNINSTSNGKNLISYEEGLAMAKKIGALRYLECSAKLNKGVNEAFTEAARVALTA 213

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BLAST of Rho-related GTP-binding protein vs. Ensembl Yeast
Match: RHO2 (Non-essential small GTPase of the Rho/Rac family of Ras-like proteins; involved in the establishment of cell polarity and in microtubule assembly [Source:SGD;Acc:S000005034])

HSP 1 Score: 194.512 bits (493), Expect = 8.464e-63
Identity = 98/180 (54.44%), Postives = 122/180 (67.78%), Query Frame = 1

Query:   37 AIRKKLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYVADIEVDNKQVELALWDTAGQEDYDRLRPLSYPDTDVILMCFSIDSTDSLENIVEKWYPEVKHFCPNVPIILVGNKKDLRNDERARHELAKMRQELVKYEDGLLTADKINAVKYLECSAKTKDGVREVFETATRAALSVK 576
            A+R+KLVI+GDGACGKT LL VF+  +FPE Y PTVFENYV D  VD  +V L LWDTAGQE+Y+RLRP SY   D+IL+ F++D+ +SL N   KW  E   +CP+ PI+LVG KKDLR +    H       E+V  ED    A  I A KY+ECSA T +GV +VFE ATR +L +K
Sbjct:    5 AVRRKLVIIGDGACGKTSLLYVFTLGKFPEQYHPTVFENYVTDCRVDGIKVSLTLWDTAGQEEYERLRPFSYSKADIILIGFAVDNFESLINARTKWADEALRYCPDAPIVLVGLKKDLRQEA---HFKENATDEMVPIEDAKQVARAIGAKKYMECSALTGEGVDDVFEVATRTSLLMK 181

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BLAST of Rho-related GTP-binding protein vs. Ensembl Yeast
Match: RHO4 (Non-essential small GTPase; member of the Rho/Rac subfamily of Ras-like proteins; likely to be involved in the establishment of cell polarity; has long N-terminal extension that plays an important role in Rho4p function and is shared with Rho4 homologs in other yeasts and filamentous fungi [Source:SGD;Acc:S000001763])

HSP 1 Score: 184.496 bits (467), Expect = 1.234e-57
Identity = 89/175 (50.86%), Postives = 120/175 (68.57%), Query Frame = 1

Query:   49 KLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYVADIEVDNKQV-ELALWDTAGQEDYDRLRPLSYPDTDVILMCFSIDSTDSLENIVEKWYPEVKHFCPNVPIILVGNKKDLRNDERARHELAKMRQELVKYEDGLLTADKINAVKYLECSAKTKDGVREVFETATRAALS 570
            K+V+VGDGA GKTCLLI + +  FP  Y+PT+FENYV +IE  N Q+ ELALWDTAGQE+Y RLRPLSY + DV+++C+S+ S  SL+N+ + W+PEVKHFCP+ PI+LVG K DL          A    +LV+       A ++ A  +++CSA+ K+ + EVFETA    LS
Sbjct:   74 KIVVVGDGAVGKTCLLISYVQGTFPTDYIPTIFENYVTNIEGPNGQIIELALWDTAGQEEYSRLRPLSYTNADVLMVCYSVGSKTSLKNVEDLWFPEVKHFCPSTPIMLVGLKSDLYE--------ADNLSDLVEPSSAESLAKRLGAFAHIQCSARLKENIDEVFETAIHTLLS 240

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BLAST of Rho-related GTP-binding protein vs. Ensembl Nematostella
Match: EDO39465 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S9Y5])

HSP 1 Score: 323.939 bits (829), Expect = 2.286e-113
Identity = 158/180 (87.78%), Postives = 163/180 (90.56%), Query Frame = 1

Query:   31 MSAIRKKLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYVADIEVDNKQVELALWDTAGQEDYDRLRPLSYPDTDVILMCFSIDSTDSLENIVEKWYPEVKHFCPNVPIILVGNKKDLRNDERARHELAKMRQELVKYEDGLLTADKINAVKYLECSAKTKDGVREVFETATRAALS 570
            M+AIRKKLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYVADIEVD KQVELALWDTAGQEDYDRLRPLSYPDTDVILMCFSIDS DSLENI EKW PEVKHFCPNVPIILVGNKKDLR DE  + EL KM+QE VK E+G   ADKI+A  YLECSAKTKDGVREVFETATRAAL 
Sbjct:    1 MAAIRKKLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYVADIEVDGKQVELALWDTAGQEDYDRLRPLSYPDTDVILMCFSIDSPDSLENIPEKWTPEVKHFCPNVPIILVGNKKDLRMDENTKRELQKMKQEPVKIEEGRAMADKISAYAYLECSAKTKDGVREVFETATRAALQ 180

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BLAST of Rho-related GTP-binding protein vs. Ensembl Nematostella
Match: EDO38536 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SCK6])

HSP 1 Score: 218.779 bits (556), Expect = 6.307e-72
Identity = 108/196 (55.10%), Postives = 135/196 (68.88%), Query Frame = 1

Query:   31 MSAIRKKLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYVADIEVDNKQVELALWDTAGQEDYDRLRPLSYPDTDVILMCFSIDSTDSLENIVEKWYPEVKHFCPNVPIILVGNKKDLRNDERARHELAKMRQELVKYEDGLLTADKINAVKYLECSAKTKDGVREVFETATRAAL-----SVKHKKKKCNIL 603
            M AI  K V+VGDGA GKTCLLI ++ + FP  Y+PTVF+NY A++ VD K + L LWDTAGQEDYDRLRPLSYP TDV L+CFS+ S  S EN+  KWYPEV H CPN PI+LVG K DLR+D+    +L + +   + Y  GL  A +I AVKYLECSA T+ G++ VF+ A RA L     + K + K C +L
Sbjct:    1 MQAI--KCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDGKPINLGLWDTAGQEDYDRLRPLSYPQTDVFLICFSLISPASYENVRAKWYPEVSHHCPNTPIVLVGTKLDLRDDKETIDKLKEKKLGPIGYTQGLQMAKEIGAVKYLECSALTQKGLKTVFDEAIRAVLCPTKPAKKPRNKGCKLL 194

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BLAST of Rho-related GTP-binding protein vs. Ensembl Nematostella
Match: EDO35019 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SMN7])

HSP 1 Score: 210.305 bits (534), Expect = 1.452e-68
Identity = 100/179 (55.87%), Postives = 124/179 (69.27%), Query Frame = 1

Query:   31 MSAIRKKLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYVADIEVDNKQVELALWDTAGQEDYDRLRPLSYPDTDVILMCFSIDSTDSLENIVEKWYPEVKHFCPNVPIILVGNKKDLRNDERARHELAKMRQELVKYEDGLLTADKINAVKYLECSAKTKDGVREVFETATRAAL 567
            M AI  K V+VGDGA GKTC+LI ++ + FP  Y+PTVF+NY A++ VD + + L LWDTAGQEDYDRLRPLSYP TDV L+CFS+ S  S EN+  KWYPEV H CP  PIILVG K DLR D+    +L + +   +    GL  A +I A KYLECSA T+ G++ VF+ A RA L
Sbjct:    1 MQAI--KCVVVGDGAVGKTCMLISYTTNAFPGEYIPTVFDNYSANVMVDGRPINLGLWDTAGQEDYDRLRPLSYPQTDVFLICFSVISPASFENVRAKWYPEVSHHCPGTPIILVGTKTDLREDKEMIEKLKEKKLNPLSTSHGLQMAKEIKAAKYLECSALTQKGLKTVFDDAIRAVL 177

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BLAST of Rho-related GTP-binding protein vs. Ensembl Nematostella
Match: EDO37472 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SFJ1])

HSP 1 Score: 202.216 bits (513), Expect = 1.768e-65
Identity = 97/187 (51.87%), Postives = 128/187 (68.45%), Query Frame = 1

Query:   49 KLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYVADIEVDNKQVELALWDTAGQEDYDRLRPLSYPDTDVILMCFSIDSTDSLENIVEKWYPEVKHFCPNVPIILVGNKKDLRNDERARHELAKMRQELVKYEDGLLTADKINAVKYLECSAKTKDGVREVFETATRAALSV--KHKKKKCNIL 603
            K V+VGDGA GKTCLLI ++ ++FP  YVPTVF+NY   + +  +   L L+DTAGQEDYDRLRPLSYP TDV L+CFS+ S  S EN+ EKW PE+ H CP  P +LVG + DLR+D+    +L+K +Q+ +  E     A ++ AVKY+ECSA T+ G++ VF+ A  AAL      KKKKC +L
Sbjct:    5 KCVVVGDGAVGKTCLLISYTTNKFPSEYVPTVFDNYAVTVMIGGEPYTLGLFDTAGQEDYDRLRPLSYPQTDVFLVCFSVVSPSSFENVKEKWVPEITHHCPKTPFLLVGTQVDLRDDQGTIEKLSKNKQKPIAVEAAEKLARELRAVKYVECSALTQKGLKNVFDEAILAALEPPEPQKKKKCRLL 191

[Close]

BLAST of Rho-related GTP-binding protein vs. Ensembl Nematostella
Match: EDO42207 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S215])

HSP 1 Score: 161.77 bits (408), Expect = 2.863e-49
Identity = 82/183 (44.81%), Postives = 122/183 (66.67%), Query Frame = 1

Query:   49 KLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYVADIEVDNKQVELALWDTAGQEDYDRLRPLSYPDTDVILMCFSIDSTDSLENIVEKWYPEVKHFCPNVPIILVGNKKDLRNDERARHELA-KMRQELVKYEDGLLTADKINAVKYLECSAKTKD-GVREVFETATRAALSVKHKKKK 591
            K+++VGD  CGKT LL  + ++QF E Y  TVF +    +EVD +++EL LWDT+G EDYD +RPLSY + D++L+CF I    + ++I+EKW  EV   CPN P++LVG K+DLR++     +LA K+ Q+ V   +G   AD+I A+ Y+ECS+KT D  + +VFE  T AA++  +  +K
Sbjct:   13 KVILVGDSECGKTALLNAYVRNQFNEKYEATVFNSLSTAVEVDGERIELTLWDTSGHEDYDHVRPLSYNNVDIVLICFDISRPKTADSILEKWIIEVCDLCPNKPVLLVGCKQDLRSEVNIVSKLASKVCQQPVTSLEGRKLADRICALDYIECSSKTMDFQLEKVFEMTTLAAINKLNNHRK 195

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BLAST of Rho-related GTP-binding protein vs. Ensembl Medaka
Match: ENSORLT00000003418.2 (rho-related GTP-binding protein RhoA-C [Source:NCBI gene;Acc:101160539])

HSP 1 Score: 331.643 bits (849), Expect = 6.031e-116
Identity = 162/187 (86.63%), Postives = 168/187 (89.84%), Query Frame = 1

Query:   31 MSAIRKKLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYVADIEVDNKQVELALWDTAGQEDYDRLRPLSYPDTDVILMCFSIDSTDSLENIVEKWYPEVKHFCPNVPIILVGNKKDLRNDERARHELAKMRQELVKYEDGLLTADKINAVKYLECSAKTKDGVREVFETATRAALSVKHKKKK 591
            M+AIRKKLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYVADIEVD KQVELALWDTAGQEDYDRLRPLSYPDTDVILMCFSIDS DSLENI EKW PEVKHFCPNVPIILVGNKKDLRNDE  R ELAKM+QE VK E+    A++INA  YLECSAKTKDGVREVFE ATRAAL  K +KKK
Sbjct:    1 MAAIRKKLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYVADIEVDGKQVELALWDTAGQEDYDRLRPLSYPDTDVILMCFSIDSPDSLENIPEKWTPEVKHFCPNVPIILVGNKKDLRNDEHTRRELAKMKQEPVKSEEARDMANRINAFGYLECSAKTKDGVREVFEMATRAALQAKGRKKK 187

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BLAST of Rho-related GTP-binding protein vs. Ensembl Medaka
Match: ENSORLT00000033500.1 (transforming protein RhoA-like [Source:NCBI gene;Acc:101158607])

HSP 1 Score: 331.257 bits (848), Expect = 8.848e-116
Identity = 160/187 (85.56%), Postives = 169/187 (90.37%), Query Frame = 1

Query:   31 MSAIRKKLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYVADIEVDNKQVELALWDTAGQEDYDRLRPLSYPDTDVILMCFSIDSTDSLENIVEKWYPEVKHFCPNVPIILVGNKKDLRNDERARHELAKMRQELVKYEDGLLTADKINAVKYLECSAKTKDGVREVFETATRAALSVKHKKKK 591
            MSAIRKKLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYVADIEVD +QVELALWDTAGQEDYDRLRPLSYPDTDVILMCFS+DS DSLENI EKW PEVKHFCPNVPIILVGNKKDLR+DE AR ELAKM+QE VK+EDG   A++I+A  Y ECSAKTKDGVREVFE ATRAAL  K  +KK
Sbjct:    1 MSAIRKKLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYVADIEVDGRQVELALWDTAGQEDYDRLRPLSYPDTDVILMCFSVDSPDSLENIPEKWTPEVKHFCPNVPIILVGNKKDLRHDEHARRELAKMKQEPVKFEDGREMANRISAYGYQECSAKTKDGVREVFEMATRAALQAKRNRKK 187

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BLAST of Rho-related GTP-binding protein vs. Ensembl Medaka
Match: ENSORLT00000023517.2 (transforming protein RhoA [Source:NCBI gene;Acc:101173444])

HSP 1 Score: 328.946 bits (842), Expect = 7.241e-115
Identity = 162/193 (83.94%), Postives = 170/193 (88.08%), Query Frame = 1

Query:   31 MSAIRKKLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYVADIEVDNKQVELALWDTAGQEDYDRLRPLSYPDTDVILMCFSIDSTDSLENIVEKWYPEVKHFCPNVPIILVGNKKDLRNDERARHELAKMRQELVKYEDGLLTADKINAVKYLECSAKTKDGVREVFETATRAALSVKHKKK--KCNIL 603
            M+AIRKKLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYVADIEVD KQVELALWDTAGQEDYDRLRPLSYPDTDVILMCFSIDS DSLENI EKW PEVKHFCPNVPIILVGNKKDLRNDE  R ELAKM+QE VK EDG   A++I A  Y+ECSAKTKDGVREVFE ATRAAL  +  KK  +C +L
Sbjct:    1 MAAIRKKLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYVADIEVDGKQVELALWDTAGQEDYDRLRPLSYPDTDVILMCFSIDSPDSLENIPEKWTPEVKHFCPNVPIILVGNKKDLRNDEHTRRELAKMKQEPVKPEDGRDMANRIGASGYMECSAKTKDGVREVFEMATRAALQARRGKKSNRCVLL 193

[Close]

BLAST of Rho-related GTP-binding protein vs. Ensembl Medaka
Match: rhocb (rho-related GTP-binding protein RhoA-C [Source:NCBI gene;Acc:101155194])

HSP 1 Score: 326.25 bits (835), Expect = 8.503e-114
Identity = 157/193 (81.35%), Postives = 171/193 (88.60%), Query Frame = 1

Query:   31 MSAIRKKLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYVADIEVDNKQVELALWDTAGQEDYDRLRPLSYPDTDVILMCFSIDSTDSLENIVEKWYPEVKHFCPNVPIILVGNKKDLRNDERARHELAKMRQELVKYEDGLLTADKINAVKYLECSAKTKDGVREVFETATRAALSVKHKKKK--CNIL 603
            M+A+RKKLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENY+ADIEVD +QVELALWDTAGQEDYDRLRPLSYPDTDVILMCFSIDS DSLENI EKW PEVKHFCPNVPIILVGNKKDLRND+  R EL KM+QE V++E+G   A +I+A  YLECSAKTKDGVR+VFE ATRAAL  + KKKK  C +L
Sbjct:    1 MAALRKKLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYIADIEVDGRQVELALWDTAGQEDYDRLRPLSYPDTDVILMCFSIDSPDSLENIPEKWTPEVKHFCPNVPIILVGNKKDLRNDDHTRRELGKMKQEPVRFEEGRDMASRIDAFGYLECSAKTKDGVRDVFEMATRAALQARKKKKKGGCQLL 193

[Close]

BLAST of Rho-related GTP-binding protein vs. Ensembl Medaka
Match: ENSORLT00000024724.2 (transforming protein RhoA [Source:NCBI gene;Acc:101173444])

HSP 1 Score: 325.479 bits (833), Expect = 1.237e-113
Identity = 160/188 (85.11%), Postives = 166/188 (88.30%), Query Frame = 1

Query:   31 MSAIRKKLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYVADIEVDNKQVELALWDTAGQEDYDRLRPLSYPDTDVILMCFSIDSTDSLENIVEKWYPEVKHFCPNVPIILVGNKKDLRNDERARHELAKMRQELVKYEDGLLTADKINAVKYLECSAKTKDGVREVFETATRAALSVKHKKKKC 594
            M+AIRKKLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYVADIEVD KQVELALWDTAGQEDYDRLRPLSYPDTDVILMCFSIDS DSLENI EKW PEVKHFCPNVPIILVGNKKDLRNDE  R ELAKM+QE VK EDG   A++I A  Y+ECSAKTKDGVREVFE ATRAAL V    + C
Sbjct:    1 MAAIRKKLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYVADIEVDGKQVELALWDTAGQEDYDRLRPLSYPDTDVILMCFSIDSPDSLENIPEKWTPEVKHFCPNVPIILVGNKKDLRNDEHTRRELAKMKQEPVKPEDGRDMANRIGASGYMECSAKTKDGVREVFEMATRAALQVYPACEGC 188

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BLAST of Rho-related GTP-binding protein vs. Planmine SMEST
Match: SMESG000001635.1 (SMESG000001635.1)

HSP 1 Score: 394.43 bits (1012), Expect = 7.345e-141
Identity = 191/191 (100.00%), Postives = 191/191 (100.00%), Query Frame = 1

Query:   31 MSAIRKKLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYVADIEVDNKQVELALWDTAGQEDYDRLRPLSYPDTDVILMCFSIDSTDSLENIVEKWYPEVKHFCPNVPIILVGNKKDLRNDERARHELAKMRQELVKYEDGLLTADKINAVKYLECSAKTKDGVREVFETATRAALSVKHKKKKCNIL 603
            MSAIRKKLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYVADIEVDNKQVELALWDTAGQEDYDRLRPLSYPDTDVILMCFSIDSTDSLENIVEKWYPEVKHFCPNVPIILVGNKKDLRNDERARHELAKMRQELVKYEDGLLTADKINAVKYLECSAKTKDGVREVFETATRAALSVKHKKKKCNIL
Sbjct:    1 MSAIRKKLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYVADIEVDNKQVELALWDTAGQEDYDRLRPLSYPDTDVILMCFSIDSTDSLENIVEKWYPEVKHFCPNVPIILVGNKKDLRNDERARHELAKMRQELVKYEDGLLTADKINAVKYLECSAKTKDGVREVFETATRAALSVKHKKKKCNIL 191

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BLAST of Rho-related GTP-binding protein vs. Planmine SMEST
Match: SMESG000022390.1 (SMESG000022390.1)

HSP 1 Score: 309.301 bits (791), Expect = 3.236e-107
Identity = 156/194 (80.41%), Postives = 172/194 (88.66%), Query Frame = 1

Query:   28 LMSAIRKKLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYVADIEVDNKQVELALWDTAGQEDYDRLRPLSYPDTDVILMCFSIDSTDSLENIVEKWYPEVKHFCPNVPIILVGNKKDLRNDERARHELAKMRQELVKYEDGLLTADKINAVKYLECSAKTKDGVREVFETATRAALSVKHKKK--KCNIL 603
            + ++IRKKLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYVADIEVD+K VELALWDTAGQEDYDRLRPLSYPDTDVILMCFSIDS+DSLENI EKW PEVKHFC NVPIILVGNKKDLRND+ +R +  K + E+VK+EDG   AD+I A  Y+ECSAKTKDGVREVFETAT+AAL  K KKK  KC++L
Sbjct:    1 MSTSIRKKLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYVADIEVDSKSVELALWDTAGQEDYDRLRPLSYPDTDVILMCFSIDSSDSLENIPEKWTPEVKHFCQNVPIILVGNKKDLRNDDSSRKD-GKNKVEIVKFEDGKAMADRIGAYAYIECSAKTKDGVREVFETATKAALQSKKKKKNIKCDLL 193

[Close]

BLAST of Rho-related GTP-binding protein vs. Planmine SMEST
Match: SMESG000024961.1 (SMESG000024961.1)

HSP 1 Score: 221.09 bits (562), Expect = 1.515e-72
Identity = 106/186 (56.99%), Postives = 129/186 (69.35%), Query Frame = 1

Query:   49 KLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYVADIEVDNKQVELALWDTAGQEDYDRLRPLSYPDTDVILMCFSIDSTDSLENIVEKWYPEVKHFCPNVPIILVGNKKDLRNDERARHELAKMRQELVKYEDGLLTADKINAVKYLECSAKTKDGVREVFETATRAALSVKHKKKK-CNIL 603
            K V+VGDGA GKTCLLI ++ + FP  Y+PTVF+NY A++ VDNK V L LWDTAGQEDYDRLRPLSYP TDV L+CFS+ ++ S EN+  KWYPE+ H CPN PIILVG K DLR +          R   + Y  GL+ A +I AVKYLECSA T+ G++ VF+ A RA L  K  +KK C  L
Sbjct:    5 KCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDNKPVNLGLWDTAGQEDYDRLRPLSYPQTDVFLICFSLINSSSYENVRAKWYPEITHHCPNTPIILVGTKLDLRENHMNGEAGKDRRNTPISYPQGLVLAKEIGAVKYLECSALTQKGLKSVFDEAIRAVLCPKPPRKKTCKFL 190

[Close]

BLAST of Rho-related GTP-binding protein vs. Planmine SMEST
Match: SMESG000024968.1 (SMESG000024968.1)

HSP 1 Score: 211.075 bits (536), Expect = 1.016e-68
Identity = 103/187 (55.08%), Postives = 128/187 (68.45%), Query Frame = 1

Query:   49 KLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYVADIEVDNKQVELALWDTAGQEDYDRLRPLSYPDTDVILMCFSIDSTDSLENIVEKWYPEVKHFCPNVPIILVGNKKDLRNDERARHELAKMRQELVKYEDGLLTADKINAVKYLECSAKTKDGVREVFETATRAALSVKHK--KKKCNIL 603
            K V+VGDGA GKTCLLI ++   FP  Y+PTVF+NY A+I VDNK V L LWDTAGQEDYDRLRPLSYP TDV ++CFS+ +  S EN+  KWYPEV + CPN PIILVG K DLR++ +            + Y  GL+   +I A KYLECSA T+ G++ VF+ + R  L  K K  KK+C+IL
Sbjct:    5 KCVVVGDGAVGKTCLLISYTTSAFPGEYIPTVFDNYSANIMVDNKPVNLGLWDTAGQEDYDRLRPLSYPQTDVFIICFSLVNPSSYENVRAKWYPEVNNHCPNTPIILVGTKLDLRDESQTNKTGGH-----ISYPQGLILMKEIGAKKYLECSALTQTGLKTVFDESIRVVLCPKQKQNKKRCSIL 186

[Close]

BLAST of Rho-related GTP-binding protein vs. Planmine SMEST
Match: SMESG000005010.1 (SMESG000005010.1)

HSP 1 Score: 199.134 bits (505), Expect = 6.832e-64
Identity = 96/176 (54.55%), Postives = 125/176 (71.02%), Query Frame = 1

Query:   49 KLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYVADIEVDNKQVELALWDTAGQEDYDRLRPLSYPDTDVILMCFSIDSTDSLENIVEKWYPEVKHFCPNVPIILVGNKKDLRNDERARHELAK--MRQELVKYEDGLLTADKINAVKYLECSAKTKDGVREVFETATRAALS 570
            K V+VGDGA GKTC+LI ++ D FP  +VPTVF+N  A++ ++   + L LWDTAGQE+YDRLRPLSYP+TDV L+CFS+ + DS  N+ EKWY EV HF    PIILVG K DLR +ERA +E  K  +R   V Y+ GL    +I AVKY+ECSA+T+  +R+VFE A R  ++
Sbjct:    5 KCVVVGDGAVGKTCILISYTTDAFPTTHVPTVFDNMSANVMIEGTPINLGLWDTAGQEEYDRLRPLSYPETDVFLICFSLVNKDSFANVKEKWYKEVSHFSKETPIILVGTKLDLR-EERALNENDKNQIRSSPVTYQQGLALCQEIGAVKYIECSARTQVNLRQVFEEAIRVVIN 179

The following BLAST results are available for this feature:

BLAST of Rho-related GTP-binding protein vs. Ensembl Human
BLAST of Rho-related GTP-binding protein vs. Ensembl Celegans
BLAST of Rho-related GTP-binding protein vs. Ensembl Fly
BLAST of Rho-related GTP-binding protein vs. Ensembl Zebrafish
BLAST of Rho-related GTP-binding protein vs. Ensembl Xenopus
BLAST of Rho-related GTP-binding protein vs. Ensembl Mouse
BLAST of Rho-related GTP-binding protein vs. UniProt/SwissProt
BLAST of Rho-related GTP-binding protein vs. TrEMBL
BLAST of Rho-related GTP-binding protein vs. Ensembl Cavefish
BLAST of Rho-related GTP-binding protein vs. Ensembl Sea Lamprey
BLAST of Rho-related GTP-binding protein vs. Ensembl Yeast
BLAST of Rho-related GTP-binding protein vs. Ensembl Nematostella
BLAST of Rho-related GTP-binding protein vs. Ensembl Medaka
BLAST of Rho-related GTP-binding protein vs. Planmine SMEST

BLAST of Rho-related GTP-binding protein vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5


Match Name	E-value	Identity	Description
RHOA	6.011e-115	84.29	ras homolog family member A [Source:HGNC Symbol;Ac...	[more]
RHOC	6.807e-113	81.87	ras homolog family member C [Source:HGNC Symbol;Ac...	[more]
RHOC	6.807e-113	81.87	ras homolog family member C [Source:HGNC Symbol;Ac...	[more]
RHOC	6.807e-113	81.87	ras homolog family member C [Source:HGNC Symbol;Ac...	[more]
RHOC	6.807e-113	81.87	ras homolog family member C [Source:HGNC Symbol;Ac...	[more]

BLAST of Rho-related GTP-binding protein vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 5


Match Name	E-value	Identity	Description
rho-1	1.587e-108	83.33	Ras-like GTP-binding protein rhoA [Source:UniProt...	[more]
ced-10	3.214e-73	55.44	Ras-related protein ced-10 [Source:UniProtKB/Swis...	[more]
mig-2	1.115e-68	52.94	Rac-like GTPase [Source:UniProtKB/TrEMBL;Acc:G5EB...	[more]
cdc-42	3.391e-65	52.94	Cell division control protein 42 homolog [Source:...	[more]
rac-2	1.169e-64	48.73	Ras-related protein rac-2 [Source:UniProtKB/Swiss...	[more]

BLAST of Rho-related GTP-binding protein vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5


Match Name	E-value	Identity	Description
Rho1	7.898e-113	82.29	gene:FBgn0014020 transcript:FBtr0087212	[more]
Rho1	7.898e-113	82.29	gene:FBgn0014020 transcript:FBtr0087213	[more]
Rho1	7.898e-113	82.29	gene:FBgn0014020 transcript:FBtr0087216	[more]
Rho1	7.898e-113	82.29	gene:FBgn0014020 transcript:FBtr0087214	[more]
Rho1	7.898e-113	82.29	gene:FBgn0014020 transcript:FBtr0087211	[more]

BLAST of Rho-related GTP-binding protein vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5


Match Name	E-value	Identity	Description
rhoac	7.006e-116	84.82	ras homolog gene family, member Ac [Source:NCBI ge...	[more]
rhocb	8.319e-115	83.25	ras homolog family member Cb [Source:NCBI gene;Acc...	[more]
rhoaa	8.319e-115	83.94	ras homolog gene family, member Aa [Source:NCBI ge...	[more]
rhoaa	8.319e-115	83.94	ras homolog gene family, member Aa [Source:NCBI ge...	[more]
rhocb	8.319e-115	83.25	ras homolog family member Cb [Source:NCBI gene;Acc...	[more]

BLAST of Rho-related GTP-binding protein vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5


Match Name	E-value	Identity	Description
cnn3	3.948e-117	86.01	calponin 3, acidic [Source:Xenbase;Acc:XB-GENE-951...	[more]
plek	1.314e-114	83.68	pleckstrin [Source:Xenbase;Acc:XB-GENE-484214]	[more]
plek	2.695e-114	83.77	pleckstrin [Source:Xenbase;Acc:XB-GENE-484214]	[more]
nsd3	1.570e-113	83.96	nuclear receptor binding SET domain protein 3 [Sou...	[more]
man1a2	3.388e-112	83.78	mannosidase, alpha, class 1A, member 2 [Source:Xen...	[more]

BLAST of Rho-related GTP-binding protein vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5


Match Name	E-value	Identity	Description
Rhoa	3.950e-115	84.29	ras homolog family member A [Source:MGI Symbol;Acc...	[more]
Rhoc	4.673e-113	81.87	ras homolog family member C [Source:MGI Symbol;Acc...	[more]
Rhoc	4.673e-113	81.87	ras homolog family member C [Source:MGI Symbol;Acc...	[more]
Rhoc	4.673e-113	81.87	ras homolog family member C [Source:MGI Symbol;Acc...	[more]
Rhob	5.572e-109	81.18	ras homolog family member B [Source:MGI Symbol;Acc...	[more]

BLAST of Rho-related GTP-binding protein vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5


Match Name	E-value	Identity	Description
sp\|Q7T2E8\|RHOAC_DANRE	5.289e-115	84.82	Rho-related GTP-binding protein RhoA-C OS=Danio re...	[more]
sp\|P61589\|RHOA_RAT	2.763e-114	84.29	Transforming protein RhoA OS=Rattus norvegicus OX=...	[more]
sp\|Q9QUI0\|RHOA_MOUSE	2.763e-114	84.29	Transforming protein RhoA OS=Mus musculus OX=10090...	[more]
sp\|Q5REY6\|RHOA_PONAB	2.887e-114	84.29	Transforming protein RhoA OS=Pongo abelii OX=9601 ...	[more]
sp\|P61586\|RHOA_HUMAN	2.887e-114	84.29	Transforming protein RhoA OS=Homo sapiens OX=9606 ...	[more]

BLAST of Rho-related GTP-binding protein vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5


Match Name	E-value	Identity	Description
F2W7E1	2.641e-137	100.00	Rho2 GTPase OS=Dugesia japonica OX=6161 PE=2 SV=1	[more]
Q5DDX1	9.677e-122	88.54	Rho-related GTP-binding protein isoform 1 OS=Schis...	[more]
A0A5J4NU18	1.189e-120	89.06	Ras protein family, member A OS=Paragonimus wester...	[more]
A0A504YED6	1.309e-119	88.54	Ras GTP-binding protein Rho1 OS=Fasciola gigantica...	[more]
A0A4E0R7E0	1.309e-119	88.54	Ras GTP-binding protein Rho1 OS=Fasciola hepatica ...	[more]

BLAST of Rho-related GTP-binding protein vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5


Match Name	E-value	Identity	Description
rhocb	1.763e-115	83.77	rho-related GTP-binding protein RhoA-D [Source:NCB...	[more]
rhocb	2.091e-115	83.77	rho-related GTP-binding protein RhoA-D [Source:NCB...	[more]
rhoca	2.333e-115	83.77	rho-related GTP-binding protein RhoA-D-like [Sourc...	[more]
rhoaa	2.547e-115	84.46	rho-related GTP-binding protein RhoA-A [Source:NCB...	[more]
rhoab	5.481e-115	83.94	rho-related GTP-binding protein RhoA-B [Source:NCB...	[more]

BLAST of Rho-related GTP-binding protein vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 5


Match Name	E-value	Identity	Description
ENSPMAT00000004439.1	2.820e-115	82.90	pep scaffold:Pmarinus_7.0:GL476335:1598569:1600956...	[more]
ENSPMAT00000001838.1	6.563e-115	86.41	pep scaffold:Pmarinus_7.0:GL478831:173097:182385:-...	[more]
ENSPMAT00000002754.1	4.043e-103	73.44	pep scaffold:Pmarinus_7.0:GL476453:253767:255265:1...	[more]
ENSPMAT00000008827.1	3.105e-95	73.87	pep scaffold:Pmarinus_7.0:GL480655:11470:16574:-1 ...	[more]
ENSPMAT00000006108.1	3.401e-90	92.65	pep scaffold:Pmarinus_7.0:GL480344:135:8553:-1 gen...	[more]

BLAST of Rho-related GTP-binding protein vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 5


Match Name	E-value	Identity	Description
RHO1	2.109e-91	70.49	GTP-binding protein of the rho subfamily of Ras-li...	[more]
CDC42	1.355e-66	53.48	Small rho-like GTPase; essential for establishment...	[more]
RHO3	3.683e-65	50.75	Non-essential small GTPase of the Rho/Rac family o...	[more]
RHO2	8.464e-63	54.44	Non-essential small GTPase of the Rho/Rac family o...	[more]
RHO4	1.234e-57	50.86	Non-essential small GTPase; member of the Rho/Rac ...	[more]

BLAST of Rho-related GTP-binding protein vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 5


Match Name	E-value	Identity	Description
EDO39465	2.286e-113	87.78	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO38536	6.307e-72	55.10	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO35019	1.452e-68	55.87	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO37472	1.768e-65	51.87	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO42207	2.863e-49	44.81	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]

BLAST of Rho-related GTP-binding protein vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5


Match Name	E-value	Identity	Description
ENSORLT00000003418.2	6.031e-116	86.63	rho-related GTP-binding protein RhoA-C [Source:NCB...	[more]
ENSORLT00000033500.1	8.848e-116	85.56	transforming protein RhoA-like [Source:NCBI gene;A...	[more]
ENSORLT00000023517.2	7.241e-115	83.94	transforming protein RhoA [Source:NCBI gene;Acc:10...	[more]
rhocb	8.503e-114	81.35	rho-related GTP-binding protein RhoA-C [Source:NCB...	[more]
ENSORLT00000024724.2	1.237e-113	85.11	transforming protein RhoA [Source:NCBI gene;Acc:10...	[more]

BLAST of Rho-related GTP-binding protein vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5


Match Name	E-value	Identity	Description
SMESG000001635.1	7.345e-141	100.00	SMESG000001635.1	[more]
SMESG000022390.1	3.236e-107	80.41	SMESG000022390.1	[more]
SMESG000024961.1	1.515e-72	56.99	SMESG000024961.1	[more]
SMESG000024968.1	1.016e-68	55.08	SMESG000024968.1	[more]
SMESG000005010.1	6.832e-64	54.55	SMESG000005010.1	[more]

Analyses

This transcript is derived from or has results from the following analyses


Analysis Name	Date Performed
Embryonic Stages	2016-07-25
Schmidtea mediterranea smed_20140614 BLASTX Human e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL	2020-05-01
Schmidtea mediterranea Sexual smed_20140614 transcriptome	2016-07-25
Schmidtea mediteranean smed_20140614 Interproscan	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST	2020-05-08

Sequences

The following sequences are available for this feature:

transcript sequence
protein sequence

transcript sequence

>SMED30013470 ID=SMED30013470|Name=Rho-related GTP-binding protein|organism=Schmidtea mediterranea sexual|type=transcript|length=828bp
ATCTATATAAATCTTATATGAAATTAGCTTATGTCGGCTATTCGGAAGAA
ATTAGTTATTGTTGGTGATGGTGCATGTGGTAAAACATGTTTGCTTATTG
TGTTTAGCAAAGATCAATTTCCCGAAGTCTATGTTCCCACAGTTTTCGAA
AATTATGTGGCTGATATTGAAGTAGACAATAAACAAGTTGAATTAGCCTT
ATGGGATACTGCTGGTCAGGAAGATTATGATAGATTGCGTCCTTTGTCTT
ATCCAGATACTGATGTTATTCTTATGTGCTTTTCTATCGATAGTACCGAT
AGTTTAGAAAATATCGTTGAAAAGTGGTATCCAGAAGTGAAGCACTTTTG
TCCCAATGTGCCAATTATATTAGTGGGTAACAAAAAAGATTTACGAAACG
ATGAAAGAGCTCGTCATGAATTGGCTAAAATGCGCCAAGAATTAGTTAAA
TATGAAGACGGGTTATTGACTGCTGACAAAATAAATGCTGTAAAATATTT
AGAATGCTCAGCGAAAACGAAAGACGGCGTACGAGAGGTATTTGAGACAG
CTACAAGAGCAGCTCTTTCAGTCAAACATAAGAAAAAGAAGTGCAATATA
CTCTAAATAAAATTTTACTTGATTGTGCTTTAACATTAATTTTATATTAA
TTGTGAGTCTGAGATATAGTGATTAGTTGAGAACATTCATATGTATTTGA
GTCTGTCAAAATTCTTGAAGTTTAACAATGGATCGGTTTTGTTTTGCAAT
AAAGATTGGAAAATTTATTTATTAACAGTATTATCAAAATTTTATTTGAT
ATATAATACAACCATTTATATTTGAAAA

protein sequence of SMED30013470-orf-1

>SMED30013470-orf-1 ID=SMED30013470-orf-1|Name=SMED30013470-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=192bp
MSAIRKKLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYVADIEVDN
KQVELALWDTAGQEDYDRLRPLSYPDTDVILMCFSIDSTDSLENIVEKWY
PEVKHFCPNVPIILVGNKKDLRNDERARHELAKMRQELVKYEDGLLTADK
INAVKYLECSAKTKDGVREVFETATRAALSVKHKKKKCNIL*

Annotated Terms

The following terms have been associated with this transcript:

Vocabulary: **molecular function**
Term	Definition
GO:0003924	GTPase activity
GO:0005525	GTP binding
GO:0000166	nucleotide binding

Vocabulary: **Planarian Anatomy**
Term	Definition
PLANA:0000020	protonephridia
PLANA:0000101	muscle cell

Vocabulary: **INTERPRO**
Term	Definition
IPR005225	Small_GTP-bd_dom
IPR003578	Small_GTPase_Rho
IPR027417	P-loop_NTPase
IPR001806	Small_GTPase

Vocabulary: **biological process**
Term	Definition
GO:0007264	small GTPase mediated signal transduction
GO:0044319	wound healing, spreading of cells
GO:1902766	skeletal muscle satellite cell migration

Vocabulary: **cellular component**
Term	Definition
GO:0005622	intracellular
GO:0005886	plasma membrane
GO:0016020	membrane

InterPro

Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01


IPR Term	IPR Description	Source	Source Term	Source Description	Alignment
None	No IPR available	PRINTS	PR00449	RASTRNSFRMNG	coord: 29..45 score: 28.5 coord: 46..68 score: 47.76 coord: 6..27 score: 47.14 coord: 108..121 score: 59.9 coord: 156..178 score: 37.58
None	No IPR available	SMART	SM00173	ras_sub_4	coord: 7..181 e-value: 8.5E-21 score: 85.1
None	No IPR available	SMART	SM00174	rho_sub_3	coord: 8..181 e-value: 2.2E-122 score: 422.5
None	No IPR available	SMART	SM00175	rab_sub_5	coord: 7..181 e-value: 1.2E-20 score: 84.6
None	No IPR available	SMART	SM00176	ran_sub_2	coord: 11..191 e-value: 0.0036 score: -3.0
None	No IPR available	GENE3D	G3DSA:3.40.50.300		coord: 1..191 e-value: 1.3E-69 score: 235.3
None	No IPR available	PANTHER	PTHR24072:SF100	RHO-RELATED GTP-BINDING PROTEIN RHOC	coord: 1..188
None	No IPR available	PANTHER	PTHR24072	RHO FAMILY GTPASE	coord: 1..188
None	No IPR available	CDD	cd01870	RhoA_like	coord: 5..179 e-value: 1.96428E-128 score: 356.353
IPR001806	Small GTPase	PFAM	PF00071	Ras	coord: 7..178 e-value: 1.1E-57 score: 194.2
IPR005225	Small GTP-binding protein domain	TIGRFAM	TIGR00231	TIGR00231	coord: 5..158 e-value: 9.2E-43 score: 143.8
IPR003578	Small GTPase Rho	PROSITE	PS51420	RHO	coord: 1..178 score: 27.62
IPR027417	P-loop containing nucleoside triphosphate hydrolase	SUPERFAMILY	SSF52540	P-loop containing nucleoside triphosphate hydrolases	coord: 6..178