Bromodomain-containing protein 2

Overview
NameBromodomain-containing protein 2
Smed IDSMED30013454
Length (bp)2998
Neoblast Clusters

Zeng et. al., 2018




▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 



 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)




Explore this single cell expression dataset with our NB Cluster Shiny App




 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of Bromodomain-containing protein 2 (SMED30013454) t-SNE clustered cells

Violin plots show distribution of expression levels for Bromodomain-containing protein 2 (SMED30013454) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of Bromodomain-containing protein 2 (SMED30013454) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for Bromodomain-containing protein 2 (SMED30013454) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017




Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020




SMED30013454

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 12

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
X2 cellSMED30013454SMESG000015058.1 SmedASXL_012601SmedAsxl_ww_GCZZ01PMID:26114597
Zhu et al., 2015
FACS sorted cell population asexual adult RNA-sequencing evidence
nervous systemSMED30013454SMESG000015058.1 dd_Smed_v4_4933_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
gutSMED30013454SMESG000015058.1 dd_Smed_v4_4933_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
muscle cellSMED30013454SMESG000015058.1 dd_Smed_v4_4933_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
neoblastSMED30013454SMESG000015058.1 dd_Smed_v4_4933_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
pharynxSMED30013454SMESG000029685.1 SMESG000012934.1 dd_Smed_v4_6525_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
nervous systemSMED30013454SMESG000029685.1 SMESG000012934.1 dd_Smed_v4_6525_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
epidermisSMED30013454SMESG000029685.1 SMESG000012934.1 dd_Smed_v4_6525_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
neoblastSMED30013454SMESG000029685.1 SMESG000012934.1 dd_Smed_v4_6525_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
parenchymal cellSMED30013454SMESG000029685.1 SMESG000012934.1 dd_Smed_v4_6525_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
epidermisSMED30013454SMESG000015058.1 dd_Smed_v4_4933_0_1dd_Smed_v4PMID:28292427
Wurtzel et al., 2017
whole organism asexual adult single-cell RNA-sequencing evidence
epidermisSMED30013454SMESG000029685.1 SMESG000012934.1 dd_Smed_v4_6525_0_1dd_Smed_v4PMID:28292427
Wurtzel et al., 2017
whole organism asexual adult single-cell RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
BLAST of Bromodomain-containing protein 2 vs. Ensembl Human
Match: BRD4 (bromodomain containing 4 [Source:HGNC Symbol;Acc:HGNC:13575])

HSP 1 Score: 108.997 bits (271), Expect = 2.364e-23
Identity = 47/105 (44.76%), Postives = 65/105 (61.90%), Query Frame = 2
Query:  575 KKSKLEIDIKICKHIILNLVSKKYGDLNRYFLEPVDVEGLKLHDYFDIVKKPMDLGTVKNKLFDGFYQSNDEFAEDIKLIFKNCYLYNPEGHEVNRCGKLLEDIF 889
            K SK+   +K C  I+  + +KK+      F +PVDVE L LHDY DI+K PMD+ T+K+KL    Y+   EF  D++L+F NCY YNP  HEV    + L+D+F
Sbjct:  346 KSSKVSEQLKCCSGILKEMFAKKHAAYAWPFYKPVDVEALGLHDYCDIIKHPMDMSTIKSKLEAREYRDAQEFGADVRLMFSNCYKYNPPDHEVVAMARKLQDVF 450          

HSP 2 Score: 98.2117 bits (243), Expect = 5.383e-20
Identity = 49/109 (44.95%), Postives = 69/109 (63.30%), Query Frame = 2
Query:   41 TNQLLYIKKNVINVLLRNSNSESFKVPVNPELLGIPNYPDIIKYPMDFGTIKIKLDKQVYQSANECKSDFLSVFRNCYIFNEPGSLYVDMALKLENLFKRKMTDLPVPE 367
            TNQL Y+ + V+  L ++  +  F+ PV+   L +P+Y  IIK PMD GTIK +L+   Y +A EC  DF ++F NCYI+N+PG   V MA  LE LF +K+ +LP  E
Sbjct:   60 TNQLQYLLRVVLKTLWKHQFAWPFQQPVDAVKLNLPDYYKIIKTPMDMGTIKKRLENNYYWNAQECIQDFNTMFTNCYIYNKPGDDIVLMAEALEKLFLQKINELPTEE 168          

HSP 3 Score: 75.485 bits (184), Expect = 5.194e-13
Identity = 36/83 (43.37%), Postives = 52/83 (62.65%), Query Frame = 2
Query:  110 FKVPVNPELLGIPNYPDIIKYPMDFGTIKIKLDKQVYQSANECKSDFLSVFRNCYIFNEPGSLYVDMALKLENLFKRKMTDLP 358
            F  PV+ E LG+ +Y DIIK+PMD  TIK KL+ + Y+ A E  +D   +F NCY +N P    V MA KL+++F+ +   +P
Sbjct:  376 FYKPVDVEALGLHDYCDIIKHPMDMSTIKSKLEAREYRDAQEFGADVRLMFSNCYKYNPPDHEVVAMARKLQDVFEMRFAKMP 458          

HSP 4 Score: 73.1738 bits (178), Expect = 2.088e-12
Identity = 30/75 (40.00%), Postives = 46/75 (61.33%), Query Frame = 2
Query:  665 FLEPVDVEGLKLHDYFDIVKKPMDLGTVKNKLFDGFYQSNDEFAEDIKLIFKNCYLYNPEGHEVNRCGKLLEDIF 889
            F +PVD   L L DY+ I+K PMD+GT+K +L + +Y +  E  +D   +F NCY+YN  G ++    + LE +F
Sbjct:   83 FQQPVDAVKLNLPDYYKIIKTPMDMGTIKKRLENNYYWNAQECIQDFNTMFTNCYIYNKPGDDIVLMAEALEKLF 157          

HSP 5 Score: 53.1434 bits (126), Expect = 2.907e-6
Identity = 32/90 (35.56%), Postives = 51/90 (56.67%), Query Frame = 2
Query: 1805 ESKSDLKEFTIEDRMQLSQDL-RLLGDKCSEKILNIYKKTEDVQSSDG-ECEIDFQTMKLVTLHSLREFADKCLQKKREKQLKKCAVTAG 2068
            E +   K  + E++ QLS D+ +L G+K    +  I  +   +++S+  E EIDF+T+K  TL  L  +   CL+KKR+ Q +K  V AG
Sbjct:  602 EEEDKCKPMSYEEKRQLSLDINKLPGEKLGRVVHIIQSREPSLKNSNPDEIEIDFETLKPSTLRELERYVTSCLRKKRKPQAEKVDVIAG 691          
BLAST of Bromodomain-containing protein 2 vs. Ensembl Human
Match: BRD4 (bromodomain containing 4 [Source:HGNC Symbol;Acc:HGNC:13575])

HSP 1 Score: 106.301 bits (264), Expect = 4.962e-23
Identity = 47/105 (44.76%), Postives = 65/105 (61.90%), Query Frame = 2
Query:  575 KKSKLEIDIKICKHIILNLVSKKYGDLNRYFLEPVDVEGLKLHDYFDIVKKPMDLGTVKNKLFDGFYQSNDEFAEDIKLIFKNCYLYNPEGHEVNRCGKLLEDIF 889
            K SK+   +K C  I+  + +KK+      F +PVDVE L LHDY DI+K PMD+ T+K+KL    Y+   EF  D++L+F NCY YNP  HEV    + L+D+F
Sbjct:  346 KSSKVSEQLKCCSGILKEMFAKKHAAYAWPFYKPVDVEALGLHDYCDIIKHPMDMSTIKSKLEAREYRDAQEFGADVRLMFSNCYKYNPPDHEVVAMARKLQDVF 450          

HSP 2 Score: 97.0561 bits (240), Expect = 4.936e-20
Identity = 49/109 (44.95%), Postives = 69/109 (63.30%), Query Frame = 2
Query:   41 TNQLLYIKKNVINVLLRNSNSESFKVPVNPELLGIPNYPDIIKYPMDFGTIKIKLDKQVYQSANECKSDFLSVFRNCYIFNEPGSLYVDMALKLENLFKRKMTDLPVPE 367
            TNQL Y+ + V+  L ++  +  F+ PV+   L +P+Y  IIK PMD GTIK +L+   Y +A EC  DF ++F NCYI+N+PG   V MA  LE LF +K+ +LP  E
Sbjct:   60 TNQLQYLLRVVLKTLWKHQFAWPFQQPVDAVKLNLPDYYKIIKTPMDMGTIKKRLENNYYWNAQECIQDFNTMFTNCYIYNKPGDDIVLMAEALEKLFLQKINELPTEE 168          

HSP 3 Score: 73.559 bits (179), Expect = 1.222e-12
Identity = 36/83 (43.37%), Postives = 52/83 (62.65%), Query Frame = 2
Query:  110 FKVPVNPELLGIPNYPDIIKYPMDFGTIKIKLDKQVYQSANECKSDFLSVFRNCYIFNEPGSLYVDMALKLENLFKRKMTDLP 358
            F  PV+ E LG+ +Y DIIK+PMD  TIK KL+ + Y+ A E  +D   +F NCY +N P    V MA KL+++F+ +   +P
Sbjct:  376 FYKPVDVEALGLHDYCDIIKHPMDMSTIKSKLEAREYRDAQEFGADVRLMFSNCYKYNPPDHEVVAMARKLQDVFEMRFAKMP 458          

HSP 4 Score: 72.0182 bits (175), Expect = 3.216e-12
Identity = 30/75 (40.00%), Postives = 46/75 (61.33%), Query Frame = 2
Query:  665 FLEPVDVEGLKLHDYFDIVKKPMDLGTVKNKLFDGFYQSNDEFAEDIKLIFKNCYLYNPEGHEVNRCGKLLEDIF 889
            F +PVD   L L DY+ I+K PMD+GT+K +L + +Y +  E  +D   +F NCY+YN  G ++    + LE +F
Sbjct:   83 FQQPVDAVKLNLPDYYKIIKTPMDMGTIKKRLENNYYWNAQECIQDFNTMFTNCYIYNKPGDDIVLMAEALEKLF 157          
BLAST of Bromodomain-containing protein 2 vs. Ensembl Human
Match: BRD4 (bromodomain containing 4 [Source:HGNC Symbol;Acc:HGNC:13575])

HSP 1 Score: 107.071 bits (266), Expect = 5.997e-23
Identity = 47/105 (44.76%), Postives = 65/105 (61.90%), Query Frame = 2
Query:  575 KKSKLEIDIKICKHIILNLVSKKYGDLNRYFLEPVDVEGLKLHDYFDIVKKPMDLGTVKNKLFDGFYQSNDEFAEDIKLIFKNCYLYNPEGHEVNRCGKLLEDIF 889
            K SK+   +K C  I+  + +KK+      F +PVDVE L LHDY DI+K PMD+ T+K+KL    Y+   EF  D++L+F NCY YNP  HEV    + L+D+F
Sbjct:  346 KSSKVSEQLKCCSGILKEMFAKKHAAYAWPFYKPVDVEALGLHDYCDIIKHPMDMSTIKSKLEAREYRDAQEFGADVRLMFSNCYKYNPPDHEVVAMARKLQDVF 450          

HSP 2 Score: 98.2117 bits (243), Expect = 3.331e-20
Identity = 49/109 (44.95%), Postives = 69/109 (63.30%), Query Frame = 2
Query:   41 TNQLLYIKKNVINVLLRNSNSESFKVPVNPELLGIPNYPDIIKYPMDFGTIKIKLDKQVYQSANECKSDFLSVFRNCYIFNEPGSLYVDMALKLENLFKRKMTDLPVPE 367
            TNQL Y+ + V+  L ++  +  F+ PV+   L +P+Y  IIK PMD GTIK +L+   Y +A EC  DF ++F NCYI+N+PG   V MA  LE LF +K+ +LP  E
Sbjct:   60 TNQLQYLLRVVLKTLWKHQFAWPFQQPVDAVKLNLPDYYKIIKTPMDMGTIKKRLENNYYWNAQECIQDFNTMFTNCYIYNKPGDDIVLMAEALEKLFLQKINELPTEE 168          

HSP 3 Score: 75.0998 bits (183), Expect = 5.122e-13
Identity = 36/83 (43.37%), Postives = 52/83 (62.65%), Query Frame = 2
Query:  110 FKVPVNPELLGIPNYPDIIKYPMDFGTIKIKLDKQVYQSANECKSDFLSVFRNCYIFNEPGSLYVDMALKLENLFKRKMTDLP 358
            F  PV+ E LG+ +Y DIIK+PMD  TIK KL+ + Y+ A E  +D   +F NCY +N P    V MA KL+++F+ +   +P
Sbjct:  376 FYKPVDVEALGLHDYCDIIKHPMDMSTIKSKLEAREYRDAQEFGADVRLMFSNCYKYNPPDHEVVAMARKLQDVFEMRFAKMP 458          

HSP 4 Score: 72.7886 bits (177), Expect = 2.542e-12
Identity = 30/75 (40.00%), Postives = 46/75 (61.33%), Query Frame = 2
Query:  665 FLEPVDVEGLKLHDYFDIVKKPMDLGTVKNKLFDGFYQSNDEFAEDIKLIFKNCYLYNPEGHEVNRCGKLLEDIF 889
            F +PVD   L L DY+ I+K PMD+GT+K +L + +Y +  E  +D   +F NCY+YN  G ++    + LE +F
Sbjct:   83 FQQPVDAVKLNLPDYYKIIKTPMDMGTIKKRLENNYYWNAQECIQDFNTMFTNCYIYNKPGDDIVLMAEALEKLF 157          

HSP 5 Score: 51.9878 bits (123), Expect = 5.735e-6
Identity = 32/90 (35.56%), Postives = 51/90 (56.67%), Query Frame = 2
Query: 1805 ESKSDLKEFTIEDRMQLSQDL-RLLGDKCSEKILNIYKKTEDVQSSD-GECEIDFQTMKLVTLHSLREFADKCLQKKREKQLKKCAVTAG 2068
            E +   K  + E++ QLS D+ +L G+K    +  I  +   +++S+  E EIDF+T+K  TL  L  +   CL+KKR+ Q +K  V AG
Sbjct:  602 EEEDKCKPMSYEEKRQLSLDINKLPGEKLGRVVHIIQSREPSLKNSNPDEIEIDFETLKPSTLRELERYVTSCLRKKRKPQAEKVDVIAG 691          
BLAST of Bromodomain-containing protein 2 vs. Ensembl Human
Match: BRD2 (bromodomain containing 2 [Source:HGNC Symbol;Acc:HGNC:1103])

HSP 1 Score: 105.531 bits (262), Expect = 7.874e-23
Identity = 50/109 (45.87%), Postives = 66/109 (60.55%), Query Frame = 2
Query:  575 KKSKLEIDIKICKHIILNLVSKKYGDLNRYFLEPVDVEGLKLHDYFDIVKKPMDLGTVKNKLFDGFYQSNDEFAEDIKLIFKNCYLYNPEGHEVNRCGKLLEDIFNKLY 901
            KK KL   +K C  I+  L+SKK+      F +PVD   L LHDY DI+K PMDL TVK K+ +  Y+   EFA D++L+F NCY YNP  H+V    + L+D+F   Y
Sbjct:  342 KKGKLSEQLKHCNGILKELLSKKHAAYAWPFYKPVDASALGLHDYHDIIKHPMDLSTVKRKMENRDYRDAQEFAADVRLMFSNCYKYNPPDHDVVAMARKLQDVFEFRY 450          

HSP 2 Score: 98.2117 bits (243), Expect = 1.598e-20
Identity = 47/106 (44.34%), Postives = 68/106 (64.15%), Query Frame = 2
Query:   41 TNQLLYIKKNVINVLLRNSNSESFKVPVNPELLGIPNYPDIIKYPMDFGTIKIKLDKQVYQSANECKSDFLSVFRNCYIFNEPGSLYVDMALKLENLFKRKMTDLP 358
            TNQL Y+ K V+  L ++  +  F+ PV+   LG+P+Y  IIK PMD GTIK +L+   Y +A+EC  DF ++F NCYI+N+P    V MA  LE +F +K+  +P
Sbjct:   76 TNQLQYLHKVVMKALWKHQFAWPFRQPVDAVKLGLPDYHKIIKQPMDMGTIKRRLENNYYWAASECMQDFNTMFTNCYIYNKPTDDIVLMAQTLEKIFLQKVASMP 181          

HSP 3 Score: 69.707 bits (169), Expect = 1.712e-11
Identity = 30/75 (40.00%), Postives = 45/75 (60.00%), Query Frame = 2
Query:  665 FLEPVDVEGLKLHDYFDIVKKPMDLGTVKNKLFDGFYQSNDEFAEDIKLIFKNCYLYNPEGHEVNRCGKLLEDIF 889
            F +PVD   L L DY  I+K+PMD+GT+K +L + +Y +  E  +D   +F NCY+YN    ++    + LE IF
Sbjct:   99 FRQPVDAVKLGLPDYHKIIKQPMDMGTIKRRLENNYYWAASECMQDFNTMFTNCYIYNKPTDDIVLMAQTLEKIF 173          

HSP 4 Score: 68.1662 bits (165), Expect = 5.126e-11
Identity = 33/83 (39.76%), Postives = 51/83 (61.45%), Query Frame = 2
Query:  110 FKVPVNPELLGIPNYPDIIKYPMDFGTIKIKLDKQVYQSANECKSDFLSVFRNCYIFNEPGSLYVDMALKLENLFKRKMTDLP 358
            F  PV+   LG+ +Y DIIK+PMD  T+K K++ + Y+ A E  +D   +F NCY +N P    V MA KL+++F+ +   +P
Sbjct:  372 FYKPVDASALGLHDYHDIIKHPMDLSTVKRKMENRDYRDAQEFAADVRLMFSNCYKYNPPDHDVVAMARKLQDVFEFRYAKMP 454          
BLAST of Bromodomain-containing protein 2 vs. Ensembl Human
Match: BRD4 (bromodomain containing 4 [Source:HGNC Symbol;Acc:HGNC:13575])

HSP 1 Score: 106.686 bits (265), Expect = 8.028e-23
Identity = 47/105 (44.76%), Postives = 65/105 (61.90%), Query Frame = 2
Query:  575 KKSKLEIDIKICKHIILNLVSKKYGDLNRYFLEPVDVEGLKLHDYFDIVKKPMDLGTVKNKLFDGFYQSNDEFAEDIKLIFKNCYLYNPEGHEVNRCGKLLEDIF 889
            K SK+   +K C  I+  + +KK+      F +PVDVE L LHDY DI+K PMD+ T+K+KL    Y+   EF  D++L+F NCY YNP  HEV    + L+D+F
Sbjct:  346 KSSKVSEQLKCCSGILKEMFAKKHAAYAWPFYKPVDVEALGLHDYCDIIKHPMDMSTIKSKLEAREYRDAQEFGADVRLMFSNCYKYNPPDHEVVAMARKLQDVF 450          

HSP 2 Score: 98.2117 bits (243), Expect = 3.876e-20
Identity = 49/109 (44.95%), Postives = 69/109 (63.30%), Query Frame = 2
Query:   41 TNQLLYIKKNVINVLLRNSNSESFKVPVNPELLGIPNYPDIIKYPMDFGTIKIKLDKQVYQSANECKSDFLSVFRNCYIFNEPGSLYVDMALKLENLFKRKMTDLPVPE 367
            TNQL Y+ + V+  L ++  +  F+ PV+   L +P+Y  IIK PMD GTIK +L+   Y +A EC  DF ++F NCYI+N+PG   V MA  LE LF +K+ +LP  E
Sbjct:   60 TNQLQYLLRVVLKTLWKHQFAWPFQQPVDAVKLNLPDYYKIIKTPMDMGTIKKRLENNYYWNAQECIQDFNTMFTNCYIYNKPGDDIVLMAEALEKLFLQKINELPTEE 168          

HSP 3 Score: 74.7146 bits (182), Expect = 6.491e-13
Identity = 36/83 (43.37%), Postives = 52/83 (62.65%), Query Frame = 2
Query:  110 FKVPVNPELLGIPNYPDIIKYPMDFGTIKIKLDKQVYQSANECKSDFLSVFRNCYIFNEPGSLYVDMALKLENLFKRKMTDLP 358
            F  PV+ E LG+ +Y DIIK+PMD  TIK KL+ + Y+ A E  +D   +F NCY +N P    V MA KL+++F+ +   +P
Sbjct:  376 FYKPVDVEALGLHDYCDIIKHPMDMSTIKSKLEAREYRDAQEFGADVRLMFSNCYKYNPPDHEVVAMARKLQDVFEMRFAKMP 458          

HSP 4 Score: 72.4034 bits (176), Expect = 3.648e-12
Identity = 30/75 (40.00%), Postives = 46/75 (61.33%), Query Frame = 2
Query:  665 FLEPVDVEGLKLHDYFDIVKKPMDLGTVKNKLFDGFYQSNDEFAEDIKLIFKNCYLYNPEGHEVNRCGKLLEDIF 889
            F +PVD   L L DY+ I+K PMD+GT+K +L + +Y +  E  +D   +F NCY+YN  G ++    + LE +F
Sbjct:   83 FQQPVDAVKLNLPDYYKIIKTPMDMGTIKKRLENNYYWNAQECIQDFNTMFTNCYIYNKPGDDIVLMAEALEKLF 157          
BLAST of Bromodomain-containing protein 2 vs. Ensembl Celegans
Match: bet-1 (Bromodomain-containing protein bet-1 [Source:UniProtKB/Swiss-Prot;Acc:Q95Y80])

HSP 1 Score: 134.035 bits (336), Expect = 9.865e-32
Identity = 93/334 (27.84%), Postives = 152/334 (45.51%), Query Frame = 2
Query:   38 YTNQLLYIKKNVINVLLRNSNSESFKVPVNPELLGIPNYPDIIKYPMDFGTIKIKLDKQVYQSANECKSDFLSVFRNCYIFNEPGSLYVDMALKLENLFKRKMTDLPVPEHYV-----------QDSTFHTPXXXXXXXXXXXXFHTPNVKPNRLTGNTMNSIAKSDIS-----------------INQKRVRSESNNGYTKEEPLFKKSKLEI-----------DIKICKHIILNLVSKKYGDLNRYFLEPVDVEGLKLHDYFDIVKKPMDLGTVKNKLFDGFYQSNDEFAEDIKLIFKNCYLYNPEGHEVNRCGKLLEDIFNKLYQGAFGNS 922
            +TN+L YI   V+    ++ +   F+ PV+   L IP Y + +  PMD  TI+ +L    Y  A EC  D  +VF+NCY FN        MA  +  + K+ +   P  EH +             S   +  S+  K         P+   + ++  T  S A   +S                   +++  SE +    K EPL  K ++ +            +K C  ++ +  +KKY +    F EPVD E L LHDY  I+K+PMDL ++K K+  G Y+   +F  D++L+ +NC+LYNP G  V+  G   +++F++ +    G+S
Sbjct:   40 HTNKLDYIMTTVLKEAGKHKHVWPFQKPVDAVALCIPLYHERVARPMDLKTIENRLKSTYYTCAQECIDDIETVFQNCYTFNGKEDDVTIMAQNVHEVIKKSLEQAPREEHDMDVYWGKNKKKPAKSDGGSKSSSSKKNDARGPSEAPSEAGSEVSSVTTASAAAPTVSESASVAAKPERKVAGKKTGKRKAESEDDE---KPEPLRAKREVAVVKKEVHQPLLPSMKPCLKLLNDFSTKKYQEFAWPFNEPVDAEQLGLHDYHKIIKEPMDLKSMKAKMESGAYKEPSDFEHDVRLMLRNCFLYNPVGDPVHSFGLRFQEVFDRRW-AELGDS 369          
BLAST of Bromodomain-containing protein 2 vs. Ensembl Celegans
Match: bet-1 (Bromodomain-containing protein bet-1 [Source:UniProtKB/Swiss-Prot;Acc:Q95Y80])

HSP 1 Score: 133.65 bits (335), Expect = 1.131e-31
Identity = 93/334 (27.84%), Postives = 152/334 (45.51%), Query Frame = 2
Query:   38 YTNQLLYIKKNVINVLLRNSNSESFKVPVNPELLGIPNYPDIIKYPMDFGTIKIKLDKQVYQSANECKSDFLSVFRNCYIFNEPGSLYVDMALKLENLFKRKMTDLPVPEHYV-----------QDSTFHTPXXXXXXXXXXXXFHTPNVKPNRLTGNTMNSIAKSDIS-----------------INQKRVRSESNNGYTKEEPLFKKSKLEI-----------DIKICKHIILNLVSKKYGDLNRYFLEPVDVEGLKLHDYFDIVKKPMDLGTVKNKLFDGFYQSNDEFAEDIKLIFKNCYLYNPEGHEVNRCGKLLEDIFNKLYQGAFGNS 922
            +TN+L YI   V+    ++ +   F+ PV+   L IP Y + +  PMD  TI+ +L    Y  A EC  D  +VF+NCY FN        MA  +  + K+ +   P  EH +             S   +  S+  K         P+   + ++  T  S A   +S                   +++  SE +    K EPL  K ++ +            +K C  ++ +  +KKY +    F EPVD E L LHDY  I+K+PMDL ++K K+  G Y+   +F  D++L+ +NC+LYNP G  V+  G   +++F++ +    G+S
Sbjct:   40 HTNKLDYIMTTVLKEAGKHKHVWPFQKPVDAVALCIPLYHERVARPMDLKTIENRLKSTYYTCAQECIDDIETVFQNCYTFNGKEDDVTIMAQNVHEVIKKSLEQAPREEHDMDVYWGKNKKKPAKSDGGSKSSSSKKNDARGPSEAPSEAGSEVSSVTTASAAAPTVSESASVAAKPERKVAGKKTGKRKAESEDDE---KPEPLRAKREVAVVKKEVHQPLLPSMKPCLKLLNDFSTKKYQEFAWPFNEPVDAEQLGLHDYHKIIKEPMDLKSMKAKMESGAYKEPSDFEHDVRLMLRNCFLYNPVGDPVHSFGLRFQEVFDRRW-AELGDS 369          
BLAST of Bromodomain-containing protein 2 vs. Ensembl Celegans
Match: F13C5.2 (pep chromosome:WBcel235:X:593960:596289:1 gene:WBGene00017423.1 transcript:F13C5.2.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:F13C5.2)

HSP 1 Score: 67.0106 bits (162), Expect = 2.266e-11
Identity = 34/87 (39.08%), Postives = 47/87 (54.02%), Query Frame = 2
Query:  587 LEIDIKICKHIILNLVSKKYGDLNRYFLEPVDVEGLKLHDYFDIVKKPMDLGTVKNKLFDGFYQSNDEFAEDIKLIFKNCYLYNPEG 847
            L  ++K C  I+       +      F +PVDV  L L DY +++KKPMD+ T++ KL    Y +  EF ED KL+  NC  YN EG
Sbjct:  115 LHDELKKCLSILKEFEKSTHDSFTFPFRKPVDVVLLGLTDYHEVIKKPMDMSTIRKKLIGEEYDTAVEFKEDFKLMINNCLTYNNEG 201          

HSP 2 Score: 62.003 bits (149), Expect = 9.178e-10
Identity = 31/79 (39.24%), Postives = 43/79 (54.43%), Query Frame = 2
Query:  110 FKVPVNPELLGIPNYPDIIKYPMDFGTIKIKLDKQVYQSANECKSDFLSVFRNCYIFNEPGSLYVDMALKLENLFKRKM 346
            F+ PV+  LLG+ +Y ++IK PMD  TI+ KL  + Y +A E K DF  +  NC  +N  G    D AL+    F  K 
Sbjct:  141 FRKPVDVVLLGLTDYHEVIKKPMDMSTIRKKLIGEEYDTAVEFKEDFKLMINNCLTYNNEGDPVADFALQFRKKFAAKW 219          
BLAST of Bromodomain-containing protein 2 vs. Ensembl Celegans
Match: bet-2 (BET (Two bromodomains) family protein [Source:UniProtKB/TrEMBL;Acc:A0A0K3ASR2])

HSP 1 Score: 66.2402 bits (160), Expect = 1.045e-10
Identity = 34/101 (33.66%), Postives = 51/101 (50.50%), Query Frame = 2
Query:  602 KICKHIILNLVSKKYGDLNRYFLEPVDVEGLKLHDYFDIVKKPMDLGTVKNKLFDGFYQSNDEFAEDIKLIFKNCYLYNPEGHEVNRCGKLLEDIFNKLYQ 904
            K C  ++  + S K     + F  PVD   LK++DY +++  PMDL T+K KL    Y   +EF  DI L+  NC  YNP+G   +     L   F + ++
Sbjct:  558 KFCSKLLNEIHSVKNKGFAQVFYLPVDPIKLKIYDYLEVITNPMDLQTIKKKLDFKQYAEPEEFVHDINLMVDNCCKYNPKGSPAHSNALELRSFFEQRWK 658          

HSP 2 Score: 63.929 bits (154), Expect = 5.331e-10
Identity = 38/107 (35.51%), Postives = 55/107 (51.40%), Query Frame = 2
Query:   38 YTNQLLYIKKNVINVLLRNSNSESFKVPVNPELLGIPNYPDIIKYPMDFGTIKIKLDKQVYQSANECKSDFLSVFRNCYIFNEPGSLYVDMALKLENLFKRKMTDLP 358
            +TN L ++   V+   L++ +S  F++PV+   L IP Y +I+  PMD  TI+ +L    Y  A +   D   VF NCY FN P      MA  LE     ++T LP
Sbjct:  283 HTNCLDFVLFTVVKDALKHKHSWPFQLPVDAIKLEIPEYHNIVNTPMDLRTIEKRLRNLYYWCAEDAIKDINQVFINCYSFNPPEYDVYKMAKTLEKQVLSQLTQLP 389          

HSP 3 Score: 59.3066 bits (142), Expect = 1.508e-8
Identity = 29/81 (35.80%), Postives = 49/81 (60.49%), Query Frame = 2
Query:  665 FLEPVDVEGLKLHDYFDIVKKPMDLGTVKNKLFDGFYQSNDEFAEDIKLIFKNCYLYNPEGHEVNRCGKLLE-DIFNKLYQ 904
            F  PVD   L++ +Y +IV  PMDL T++ +L + +Y   ++  +DI  +F NCY +NP  ++V +  K LE  + ++L Q
Sbjct:  307 FQLPVDAIKLEIPEYHNIVNTPMDLRTIEKRLRNLYYWCAEDAIKDINQVFINCYSFNPPEYDVYKMAKTLEKQVLSQLTQ 387          

HSP 4 Score: 50.0618 bits (118), Expect = 9.156e-6
Identity = 31/88 (35.23%), Postives = 46/88 (52.27%), Query Frame = 2
Query:  101 SESFKVPVNPELLGIPNYPDIIKYPMDFGTIKIKLDKQVYQSANECKSDFLSVFRNCYIFNEPGSLYVDMALKLENLFKRKMTDLPVP 364
            ++ F +PV+P  L I +Y ++I  PMD  TIK KLD + Y    E   D   +  NC  +N  GS     AL+L + F+++    P P
Sbjct:  576 AQVFYLPVDPIKLKIYDYLEVITNPMDLQTIKKKLDFKQYAEPEEFVHDINLMVDNCCKYNPKGSPAHSNALELRSFFEQRWKLFPRP 663          
BLAST of Bromodomain-containing protein 2 vs. Ensembl Celegans
Match: bet-2 (BET (Two bromodomains) family protein [Source:UniProtKB/TrEMBL;Acc:A0A0K3ASR2])

HSP 1 Score: 66.2402 bits (160), Expect = 1.101e-10
Identity = 34/101 (33.66%), Postives = 51/101 (50.50%), Query Frame = 2
Query:  602 KICKHIILNLVSKKYGDLNRYFLEPVDVEGLKLHDYFDIVKKPMDLGTVKNKLFDGFYQSNDEFAEDIKLIFKNCYLYNPEGHEVNRCGKLLEDIFNKLYQ 904
            K C  ++  + S K     + F  PVD   LK++DY +++  PMDL T+K KL    Y   +EF  DI L+  NC  YNP+G   +     L   F + ++
Sbjct:  558 KFCSKLLNEIHSVKNKGFAQVFYLPVDPIKLKIYDYLEVITNPMDLQTIKKKLDFKQYAEPEEFVHDINLMVDNCCKYNPKGSPAHSNALELRSFFEQRWK 658          

HSP 2 Score: 63.929 bits (154), Expect = 5.392e-10
Identity = 38/107 (35.51%), Postives = 55/107 (51.40%), Query Frame = 2
Query:   38 YTNQLLYIKKNVINVLLRNSNSESFKVPVNPELLGIPNYPDIIKYPMDFGTIKIKLDKQVYQSANECKSDFLSVFRNCYIFNEPGSLYVDMALKLENLFKRKMTDLP 358
            +TN L ++   V+   L++ +S  F++PV+   L IP Y +I+  PMD  TI+ +L    Y  A +   D   VF NCY FN P      MA  LE     ++T LP
Sbjct:  283 HTNCLDFVLFTVVKDALKHKHSWPFQLPVDAIKLEIPEYHNIVNTPMDLRTIEKRLRNLYYWCAEDAIKDINQVFINCYSFNPPEYDVYKMAKTLEKQVLSQLTQLP 389          

HSP 3 Score: 59.3066 bits (142), Expect = 1.479e-8
Identity = 29/81 (35.80%), Postives = 49/81 (60.49%), Query Frame = 2
Query:  665 FLEPVDVEGLKLHDYFDIVKKPMDLGTVKNKLFDGFYQSNDEFAEDIKLIFKNCYLYNPEGHEVNRCGKLLE-DIFNKLYQ 904
            F  PVD   L++ +Y +IV  PMDL T++ +L + +Y   ++  +DI  +F NCY +NP  ++V +  K LE  + ++L Q
Sbjct:  307 FQLPVDAIKLEIPEYHNIVNTPMDLRTIEKRLRNLYYWCAEDAIKDINQVFINCYSFNPPEYDVYKMAKTLEKQVLSQLTQ 387          

HSP 4 Score: 50.447 bits (119), Expect = 8.302e-6
Identity = 31/88 (35.23%), Postives = 46/88 (52.27%), Query Frame = 2
Query:  101 SESFKVPVNPELLGIPNYPDIIKYPMDFGTIKIKLDKQVYQSANECKSDFLSVFRNCYIFNEPGSLYVDMALKLENLFKRKMTDLPVP 364
            ++ F +PV+P  L I +Y ++I  PMD  TIK KLD + Y    E   D   +  NC  +N  GS     AL+L + F+++    P P
Sbjct:  576 AQVFYLPVDPIKLKIYDYLEVITNPMDLQTIKKKLDFKQYAEPEEFVHDINLMVDNCCKYNPKGSPAHSNALELRSFFEQRWKLFPRP 663          
BLAST of Bromodomain-containing protein 2 vs. Ensembl Fly
Match: fs(1)h (gene:FBgn0004656 transcript:FBtr0333308)

HSP 1 Score: 114.39 bits (285), Expect = 2.000e-25
Identity = 55/108 (50.93%), Postives = 69/108 (63.89%), Query Frame = 2
Query:  578 KSKLEIDIKICKHIILNLVSKKYGDLNRYFLEPVDVEGLKLHDYFDIVKKPMDLGTVKNKLFDGFYQSNDEFAEDIKLIFKNCYLYNPEGHEVNRCGKLLEDIFNKLY 901
            K KL   +K C  I+  L SKK+      F +PVD E L LHDY DI+KKPMDLGTVK K+ +  Y+S  EFA D++LIF NCY YNP  H+V   G+ L+D+F   Y
Sbjct:  469 KEKLSDALKSCNEILKELFSKKHSGYAWPFYKPVDAEMLGLHDYHDIIKKPMDLGTVKRKMDNREYKSAPEFAADVRLIFTNCYKYNPPDHDVVAMGRKLQDVFEMRY 576          

HSP 2 Score: 95.9005 bits (237), Expect = 1.121e-19
Identity = 47/106 (44.34%), Postives = 68/106 (64.15%), Query Frame = 2
Query:   41 TNQLLYIKKNVINVLLRNSNSESFKVPVNPELLGIPNYPDIIKYPMDFGTIKIKLDKQVYQSANECKSDFLSVFRNCYIFNEPGSLYVDMALKLENLFKRKMTDLP 358
            TNQL Y+ K V+ V+ ++  S  F+ PV+ + L +P+Y  IIK PMD GTIK +L+   Y SA E   DF ++F NCY++N+PG   V MA  LE +F +K+  +P
Sbjct:   36 TNQLQYLIKTVMKVIWKHHFSWPFQQPVDAKKLNLPDYHKIIKQPMDMGTIKKRLENNYYWSAKETIQDFNTMFNNCYVYNKPGEDVVVMAQTLEKVFLQKIESMP 141          

HSP 3 Score: 78.1814 bits (191), Expect = 3.277e-14
Identity = 36/83 (43.37%), Postives = 54/83 (65.06%), Query Frame = 2
Query:  110 FKVPVNPELLGIPNYPDIIKYPMDFGTIKIKLDKQVYQSANECKSDFLSVFRNCYIFNEPGSLYVDMALKLENLFKRKMTDLP 358
            F  PV+ E+LG+ +Y DIIK PMD GT+K K+D + Y+SA E  +D   +F NCY +N P    V M  KL+++F+ +  ++P
Sbjct:  498 FYKPVDAEMLGLHDYHDIIKKPMDLGTVKRKMDNREYKSAPEFAADVRLIFTNCYKYNPPDHDVVAMGRKLQDVFEMRYANIP 580          

HSP 4 Score: 74.3294 bits (181), Expect = 4.421e-13
Identity = 32/75 (42.67%), Postives = 47/75 (62.67%), Query Frame = 2
Query:  665 FLEPVDVEGLKLHDYFDIVKKPMDLGTVKNKLFDGFYQSNDEFAEDIKLIFKNCYLYNPEGHEVNRCGKLLEDIF 889
            F +PVD + L L DY  I+K+PMD+GT+K +L + +Y S  E  +D   +F NCY+YN  G +V    + LE +F
Sbjct:   59 FQQPVDAKKLNLPDYHKIIKQPMDMGTIKKRLENNYYWSAKETIQDFNTMFNNCYVYNKPGEDVVVMAQTLEKVF 133          
BLAST of Bromodomain-containing protein 2 vs. Ensembl Fly
Match: fs(1)h (gene:FBgn0004656 transcript:FBtr0071122)

HSP 1 Score: 114.39 bits (285), Expect = 2.024e-25
Identity = 55/108 (50.93%), Postives = 69/108 (63.89%), Query Frame = 2
Query:  578 KSKLEIDIKICKHIILNLVSKKYGDLNRYFLEPVDVEGLKLHDYFDIVKKPMDLGTVKNKLFDGFYQSNDEFAEDIKLIFKNCYLYNPEGHEVNRCGKLLEDIFNKLY 901
            K KL   +K C  I+  L SKK+      F +PVD E L LHDY DI+KKPMDLGTVK K+ +  Y+S  EFA D++LIF NCY YNP  H+V   G+ L+D+F   Y
Sbjct:  474 KEKLSDALKSCNEILKELFSKKHSGYAWPFYKPVDAEMLGLHDYHDIIKKPMDLGTVKRKMDNREYKSAPEFAADVRLIFTNCYKYNPPDHDVVAMGRKLQDVFEMRY 581          

HSP 2 Score: 95.9005 bits (237), Expect = 1.095e-19
Identity = 47/106 (44.34%), Postives = 68/106 (64.15%), Query Frame = 2
Query:   41 TNQLLYIKKNVINVLLRNSNSESFKVPVNPELLGIPNYPDIIKYPMDFGTIKIKLDKQVYQSANECKSDFLSVFRNCYIFNEPGSLYVDMALKLENLFKRKMTDLP 358
            TNQL Y+ K V+ V+ ++  S  F+ PV+ + L +P+Y  IIK PMD GTIK +L+   Y SA E   DF ++F NCY++N+PG   V MA  LE +F +K+  +P
Sbjct:   36 TNQLQYLIKTVMKVIWKHHFSWPFQQPVDAKKLNLPDYHKIIKQPMDMGTIKKRLENNYYWSAKETIQDFNTMFNNCYVYNKPGEDVVVMAQTLEKVFLQKIESMP 141          

HSP 3 Score: 78.1814 bits (191), Expect = 3.455e-14
Identity = 36/83 (43.37%), Postives = 54/83 (65.06%), Query Frame = 2
Query:  110 FKVPVNPELLGIPNYPDIIKYPMDFGTIKIKLDKQVYQSANECKSDFLSVFRNCYIFNEPGSLYVDMALKLENLFKRKMTDLP 358
            F  PV+ E+LG+ +Y DIIK PMD GT+K K+D + Y+SA E  +D   +F NCY +N P    V M  KL+++F+ +  ++P
Sbjct:  503 FYKPVDAEMLGLHDYHDIIKKPMDLGTVKRKMDNREYKSAPEFAADVRLIFTNCYKYNPPDHDVVAMGRKLQDVFEMRYANIP 585          

HSP 4 Score: 74.3294 bits (181), Expect = 4.428e-13
Identity = 32/75 (42.67%), Postives = 47/75 (62.67%), Query Frame = 2
Query:  665 FLEPVDVEGLKLHDYFDIVKKPMDLGTVKNKLFDGFYQSNDEFAEDIKLIFKNCYLYNPEGHEVNRCGKLLEDIF 889
            F +PVD + L L DY  I+K+PMD+GT+K +L + +Y S  E  +D   +F NCY+YN  G +V    + LE +F
Sbjct:   59 FQQPVDAKKLNLPDYHKIIKQPMDMGTIKKRLENNYYWSAKETIQDFNTMFNNCYVYNKPGEDVVVMAQTLEKVF 133          
BLAST of Bromodomain-containing protein 2 vs. Ensembl Fly
Match: fs(1)h (gene:FBgn0004656 transcript:FBtr0071120)

HSP 1 Score: 114.39 bits (285), Expect = 2.024e-25
Identity = 55/108 (50.93%), Postives = 69/108 (63.89%), Query Frame = 2
Query:  578 KSKLEIDIKICKHIILNLVSKKYGDLNRYFLEPVDVEGLKLHDYFDIVKKPMDLGTVKNKLFDGFYQSNDEFAEDIKLIFKNCYLYNPEGHEVNRCGKLLEDIFNKLY 901
            K KL   +K C  I+  L SKK+      F +PVD E L LHDY DI+KKPMDLGTVK K+ +  Y+S  EFA D++LIF NCY YNP  H+V   G+ L+D+F   Y
Sbjct:  474 KEKLSDALKSCNEILKELFSKKHSGYAWPFYKPVDAEMLGLHDYHDIIKKPMDLGTVKRKMDNREYKSAPEFAADVRLIFTNCYKYNPPDHDVVAMGRKLQDVFEMRY 581          

HSP 2 Score: 95.9005 bits (237), Expect = 1.095e-19
Identity = 47/106 (44.34%), Postives = 68/106 (64.15%), Query Frame = 2
Query:   41 TNQLLYIKKNVINVLLRNSNSESFKVPVNPELLGIPNYPDIIKYPMDFGTIKIKLDKQVYQSANECKSDFLSVFRNCYIFNEPGSLYVDMALKLENLFKRKMTDLP 358
            TNQL Y+ K V+ V+ ++  S  F+ PV+ + L +P+Y  IIK PMD GTIK +L+   Y SA E   DF ++F NCY++N+PG   V MA  LE +F +K+  +P
Sbjct:   36 TNQLQYLIKTVMKVIWKHHFSWPFQQPVDAKKLNLPDYHKIIKQPMDMGTIKKRLENNYYWSAKETIQDFNTMFNNCYVYNKPGEDVVVMAQTLEKVFLQKIESMP 141          

HSP 3 Score: 78.1814 bits (191), Expect = 3.455e-14
Identity = 36/83 (43.37%), Postives = 54/83 (65.06%), Query Frame = 2
Query:  110 FKVPVNPELLGIPNYPDIIKYPMDFGTIKIKLDKQVYQSANECKSDFLSVFRNCYIFNEPGSLYVDMALKLENLFKRKMTDLP 358
            F  PV+ E+LG+ +Y DIIK PMD GT+K K+D + Y+SA E  +D   +F NCY +N P    V M  KL+++F+ +  ++P
Sbjct:  503 FYKPVDAEMLGLHDYHDIIKKPMDLGTVKRKMDNREYKSAPEFAADVRLIFTNCYKYNPPDHDVVAMGRKLQDVFEMRYANIP 585          

HSP 4 Score: 74.3294 bits (181), Expect = 4.428e-13
Identity = 32/75 (42.67%), Postives = 47/75 (62.67%), Query Frame = 2
Query:  665 FLEPVDVEGLKLHDYFDIVKKPMDLGTVKNKLFDGFYQSNDEFAEDIKLIFKNCYLYNPEGHEVNRCGKLLEDIF 889
            F +PVD + L L DY  I+K+PMD+GT+K +L + +Y S  E  +D   +F NCY+YN  G +V    + LE +F
Sbjct:   59 FQQPVDAKKLNLPDYHKIIKQPMDMGTIKKRLENNYYWSAKETIQDFNTMFNNCYVYNKPGEDVVVMAQTLEKVF 133          
BLAST of Bromodomain-containing protein 2 vs. Ensembl Fly
Match: fs(1)h (gene:FBgn0004656 transcript:FBtr0071118)

HSP 1 Score: 114.39 bits (285), Expect = 2.024e-25
Identity = 55/108 (50.93%), Postives = 69/108 (63.89%), Query Frame = 2
Query:  578 KSKLEIDIKICKHIILNLVSKKYGDLNRYFLEPVDVEGLKLHDYFDIVKKPMDLGTVKNKLFDGFYQSNDEFAEDIKLIFKNCYLYNPEGHEVNRCGKLLEDIFNKLY 901
            K KL   +K C  I+  L SKK+      F +PVD E L LHDY DI+KKPMDLGTVK K+ +  Y+S  EFA D++LIF NCY YNP  H+V   G+ L+D+F   Y
Sbjct:  474 KEKLSDALKSCNEILKELFSKKHSGYAWPFYKPVDAEMLGLHDYHDIIKKPMDLGTVKRKMDNREYKSAPEFAADVRLIFTNCYKYNPPDHDVVAMGRKLQDVFEMRY 581          

HSP 2 Score: 95.9005 bits (237), Expect = 1.095e-19
Identity = 47/106 (44.34%), Postives = 68/106 (64.15%), Query Frame = 2
Query:   41 TNQLLYIKKNVINVLLRNSNSESFKVPVNPELLGIPNYPDIIKYPMDFGTIKIKLDKQVYQSANECKSDFLSVFRNCYIFNEPGSLYVDMALKLENLFKRKMTDLP 358
            TNQL Y+ K V+ V+ ++  S  F+ PV+ + L +P+Y  IIK PMD GTIK +L+   Y SA E   DF ++F NCY++N+PG   V MA  LE +F +K+  +P
Sbjct:   36 TNQLQYLIKTVMKVIWKHHFSWPFQQPVDAKKLNLPDYHKIIKQPMDMGTIKKRLENNYYWSAKETIQDFNTMFNNCYVYNKPGEDVVVMAQTLEKVFLQKIESMP 141          

HSP 3 Score: 78.1814 bits (191), Expect = 3.455e-14
Identity = 36/83 (43.37%), Postives = 54/83 (65.06%), Query Frame = 2
Query:  110 FKVPVNPELLGIPNYPDIIKYPMDFGTIKIKLDKQVYQSANECKSDFLSVFRNCYIFNEPGSLYVDMALKLENLFKRKMTDLP 358
            F  PV+ E+LG+ +Y DIIK PMD GT+K K+D + Y+SA E  +D   +F NCY +N P    V M  KL+++F+ +  ++P
Sbjct:  503 FYKPVDAEMLGLHDYHDIIKKPMDLGTVKRKMDNREYKSAPEFAADVRLIFTNCYKYNPPDHDVVAMGRKLQDVFEMRYANIP 585          

HSP 4 Score: 74.3294 bits (181), Expect = 4.428e-13
Identity = 32/75 (42.67%), Postives = 47/75 (62.67%), Query Frame = 2
Query:  665 FLEPVDVEGLKLHDYFDIVKKPMDLGTVKNKLFDGFYQSNDEFAEDIKLIFKNCYLYNPEGHEVNRCGKLLEDIF 889
            F +PVD + L L DY  I+K+PMD+GT+K +L + +Y S  E  +D   +F NCY+YN  G +V    + LE +F
Sbjct:   59 FQQPVDAKKLNLPDYHKIIKQPMDMGTIKKRLENNYYWSAKETIQDFNTMFNNCYVYNKPGEDVVVMAQTLEKVF 133          
BLAST of Bromodomain-containing protein 2 vs. Ensembl Fly
Match: fs(1)h (gene:FBgn0004656 transcript:FBtr0301309)

HSP 1 Score: 114.39 bits (285), Expect = 2.024e-25
Identity = 55/108 (50.93%), Postives = 69/108 (63.89%), Query Frame = 2
Query:  578 KSKLEIDIKICKHIILNLVSKKYGDLNRYFLEPVDVEGLKLHDYFDIVKKPMDLGTVKNKLFDGFYQSNDEFAEDIKLIFKNCYLYNPEGHEVNRCGKLLEDIFNKLY 901
            K KL   +K C  I+  L SKK+      F +PVD E L LHDY DI+KKPMDLGTVK K+ +  Y+S  EFA D++LIF NCY YNP  H+V   G+ L+D+F   Y
Sbjct:  474 KEKLSDALKSCNEILKELFSKKHSGYAWPFYKPVDAEMLGLHDYHDIIKKPMDLGTVKRKMDNREYKSAPEFAADVRLIFTNCYKYNPPDHDVVAMGRKLQDVFEMRY 581          

HSP 2 Score: 95.9005 bits (237), Expect = 1.095e-19
Identity = 47/106 (44.34%), Postives = 68/106 (64.15%), Query Frame = 2
Query:   41 TNQLLYIKKNVINVLLRNSNSESFKVPVNPELLGIPNYPDIIKYPMDFGTIKIKLDKQVYQSANECKSDFLSVFRNCYIFNEPGSLYVDMALKLENLFKRKMTDLP 358
            TNQL Y+ K V+ V+ ++  S  F+ PV+ + L +P+Y  IIK PMD GTIK +L+   Y SA E   DF ++F NCY++N+PG   V MA  LE +F +K+  +P
Sbjct:   36 TNQLQYLIKTVMKVIWKHHFSWPFQQPVDAKKLNLPDYHKIIKQPMDMGTIKKRLENNYYWSAKETIQDFNTMFNNCYVYNKPGEDVVVMAQTLEKVFLQKIESMP 141          

HSP 3 Score: 78.1814 bits (191), Expect = 3.455e-14
Identity = 36/83 (43.37%), Postives = 54/83 (65.06%), Query Frame = 2
Query:  110 FKVPVNPELLGIPNYPDIIKYPMDFGTIKIKLDKQVYQSANECKSDFLSVFRNCYIFNEPGSLYVDMALKLENLFKRKMTDLP 358
            F  PV+ E+LG+ +Y DIIK PMD GT+K K+D + Y+SA E  +D   +F NCY +N P    V M  KL+++F+ +  ++P
Sbjct:  503 FYKPVDAEMLGLHDYHDIIKKPMDLGTVKRKMDNREYKSAPEFAADVRLIFTNCYKYNPPDHDVVAMGRKLQDVFEMRYANIP 585          

HSP 4 Score: 74.3294 bits (181), Expect = 4.428e-13
Identity = 32/75 (42.67%), Postives = 47/75 (62.67%), Query Frame = 2
Query:  665 FLEPVDVEGLKLHDYFDIVKKPMDLGTVKNKLFDGFYQSNDEFAEDIKLIFKNCYLYNPEGHEVNRCGKLLEDIF 889
            F +PVD + L L DY  I+K+PMD+GT+K +L + +Y S  E  +D   +F NCY+YN  G +V    + LE +F
Sbjct:   59 FQQPVDAKKLNLPDYHKIIKQPMDMGTIKKRLENNYYWSAKETIQDFNTMFNNCYVYNKPGEDVVVMAQTLEKVF 133          
BLAST of Bromodomain-containing protein 2 vs. Ensembl Zebrafish
Match: brd3b (bromodomain containing 3b [Source:ZFIN;Acc:ZDB-GENE-030131-5316])

HSP 1 Score: 108.227 bits (269), Expect = 1.141e-23
Identity = 50/110 (45.45%), Postives = 69/110 (62.73%), Query Frame = 2
Query:  560 EEPLFKKSKLEIDIKICKHIILNLVSKKYGDLNRYFLEPVDVEGLKLHDYFDIVKKPMDLGTVKNKLFDGFYQSNDEFAEDIKLIFKNCYLYNPEGHEVNRCGKLLEDIF 889
            ++P  KKSKL   +K C  I+  ++SKK+      F +PVD E L+LHDY +I+K+PMDL TVK K+    Y     FA D++L+F NCY YNP  HEV    + L+D+F
Sbjct:  282 QQPGNKKSKLNDHLKYCDTILKEMLSKKHAAYAWPFYKPVDAEALELHDYHEIIKQPMDLSTVKKKMDSREYPDAQNFAADVRLMFSNCYKYNPPDHEVVAMARKLQDVF 391          

HSP 2 Score: 93.5893 bits (231), Expect = 4.147e-19
Identity = 44/106 (41.51%), Postives = 65/106 (61.32%), Query Frame = 2
Query:   41 TNQLLYIKKNVINVLLRNSNSESFKVPVNPELLGIPNYPDIIKYPMDFGTIKIKLDKQVYQSANECKSDFLSVFRNCYIFNEPGSLYVDMALKLENLFKRKMTDLP 358
            TNQL Y++  V+  L ++  +  F  PV+   L +P+Y  +IK PMD GTIK +L+   Y +A EC  DF ++F NCYI+N+P    V MA  LE +F +K+  +P
Sbjct:   32 TNQLQYMQNVVVKTLWKHQFAWPFYTPVDAIKLNLPDYHKVIKNPMDMGTIKKRLENNYYWTAGECMQDFNTMFTNCYIYNKPTDDIVLMAQALEKIFLQKVAQMP 137          

HSP 3 Score: 68.1662 bits (165), Expect = 3.952e-11
Identity = 29/75 (38.67%), Postives = 43/75 (57.33%), Query Frame = 2
Query:  665 FLEPVDVEGLKLHDYFDIVKKPMDLGTVKNKLFDGFYQSNDEFAEDIKLIFKNCYLYNPEGHEVNRCGKLLEDIF 889
            F  PVD   L L DY  ++K PMD+GT+K +L + +Y +  E  +D   +F NCY+YN    ++    + LE IF
Sbjct:   55 FYTPVDAIKLNLPDYHKVIKNPMDMGTIKKRLENNYYWTAGECMQDFNTMFTNCYIYNKPTDDIVLMAQALEKIF 129          

HSP 4 Score: 67.781 bits (164), Expect = 4.897e-11
Identity = 33/83 (39.76%), Postives = 48/83 (57.83%), Query Frame = 2
Query:  110 FKVPVNPELLGIPNYPDIIKYPMDFGTIKIKLDKQVYQSANECKSDFLSVFRNCYIFNEPGSLYVDMALKLENLFKRKMTDLP 358
            F  PV+ E L + +Y +IIK PMD  T+K K+D + Y  A    +D   +F NCY +N P    V MA KL+++F+ K   +P
Sbjct:  317 FYKPVDAEALELHDYHEIIKQPMDLSTVKKKMDSREYPDAQNFAADVRLMFSNCYKYNPPDHEVVAMARKLQDVFEMKFAKMP 399          
BLAST of Bromodomain-containing protein 2 vs. Ensembl Zebrafish
Match: brd3a (bromodomain containing 3a [Source:ZFIN;Acc:ZDB-GENE-030131-6141])

HSP 1 Score: 106.301 bits (264), Expect = 2.355e-23
Identity = 49/105 (46.67%), Postives = 65/105 (61.90%), Query Frame = 2
Query:  575 KKSKLEIDIKICKHIILNLVSKKYGDLNRYFLEPVDVEGLKLHDYFDIVKKPMDLGTVKNKLFDGFYQSNDEFAEDIKLIFKNCYLYNPEGHEVNRCGKLLEDIF 889
            KK +L   +K C  I+  ++SKK+      F +PVD E L+LHDY DI+K PMDL TVK K+    YQ    FA D++L+F NCY YNP  HEV    + L+D+F
Sbjct:  287 KKGRLSEQLKYCDVILKEMLSKKHAAYAWPFYKPVDAEALELHDYHDIIKHPMDLSTVKKKMDSREYQDAQTFAADVRLMFSNCYKYNPPDHEVVAMARKLQDVF 391          

HSP 2 Score: 94.7449 bits (234), Expect = 1.200e-19
Identity = 47/106 (44.34%), Postives = 67/106 (63.21%), Query Frame = 2
Query:   41 TNQLLYIKKNVINVLLRNSNSESFKVPVNPELLGIPNYPDIIKYPMDFGTIKIKLDKQVYQSANECKSDFLSVFRNCYIFNEPGSLYVDMALKLENLFKRKMTDLP 358
            TNQL Y++  V+  L ++  +  F  PV+   LG+P+Y  IIK PMD GTIK +L+   Y SA+EC  DF ++F NCYI+N+P    V MA  LE +F +K+  +P
Sbjct:   32 TNQLQYMQNVVVKTLWKHQFAWPFYQPVDAVKLGLPDYHKIIKNPMDMGTIKKRLESVYYYSASECMQDFNTMFTNCYIYNKPTDDIVLMAQALEKIFLQKVALMP 137          

HSP 3 Score: 70.8626 bits (172), Expect = 4.285e-12
Identity = 34/83 (40.96%), Postives = 50/83 (60.24%), Query Frame = 2
Query:  110 FKVPVNPELLGIPNYPDIIKYPMDFGTIKIKLDKQVYQSANECKSDFLSVFRNCYIFNEPGSLYVDMALKLENLFKRKMTDLP 358
            F  PV+ E L + +Y DIIK+PMD  T+K K+D + YQ A    +D   +F NCY +N P    V MA KL+++F+ +   +P
Sbjct:  317 FYKPVDAEALELHDYHDIIKHPMDLSTVKKKMDSREYQDAQTFAADVRLMFSNCYKYNPPDHEVVAMARKLQDVFEMRFAKMP 399          

HSP 4 Score: 68.1662 bits (165), Expect = 2.767e-11
Identity = 31/75 (41.33%), Postives = 43/75 (57.33%), Query Frame = 2
Query:  665 FLEPVDVEGLKLHDYFDIVKKPMDLGTVKNKLFDGFYQSNDEFAEDIKLIFKNCYLYNPEGHEVNRCGKLLEDIF 889
            F +PVD   L L DY  I+K PMD+GT+K +L   +Y S  E  +D   +F NCY+YN    ++    + LE IF
Sbjct:   55 FYQPVDAVKLGLPDYHKIIKNPMDMGTIKKRLESVYYYSASECMQDFNTMFTNCYIYNKPTDDIVLMAQALEKIF 129          
BLAST of Bromodomain-containing protein 2 vs. Ensembl Zebrafish
Match: brd3b (bromodomain containing 3b [Source:ZFIN;Acc:ZDB-GENE-030131-5316])

HSP 1 Score: 107.071 bits (266), Expect = 2.474e-23
Identity = 50/110 (45.45%), Postives = 69/110 (62.73%), Query Frame = 2
Query:  560 EEPLFKKSKLEIDIKICKHIILNLVSKKYGDLNRYFLEPVDVEGLKLHDYFDIVKKPMDLGTVKNKLFDGFYQSNDEFAEDIKLIFKNCYLYNPEGHEVNRCGKLLEDIF 889
            ++P  KKSKL   +K C  I+  ++SKK+      F +PVD E L+LHDY +I+K+PMDL TVK K+    Y     FA D++L+F NCY YNP  HEV    + L+D+F
Sbjct:  282 QQPGNKKSKLNDHLKYCDTILKEMLSKKHAAYAWPFYKPVDAEALELHDYHEIIKQPMDLSTVKKKMDSREYPDAQNFAADVRLMFSNCYKYNPPDHEVVAMARKLQDVF 391          

HSP 2 Score: 92.4337 bits (228), Expect = 8.739e-19
Identity = 44/106 (41.51%), Postives = 65/106 (61.32%), Query Frame = 2
Query:   41 TNQLLYIKKNVINVLLRNSNSESFKVPVNPELLGIPNYPDIIKYPMDFGTIKIKLDKQVYQSANECKSDFLSVFRNCYIFNEPGSLYVDMALKLENLFKRKMTDLP 358
            TNQL Y++  V+  L ++  +  F  PV+   L +P+Y  +IK PMD GTIK +L+   Y +A EC  DF ++F NCYI+N+P    V MA  LE +F +K+  +P
Sbjct:   32 TNQLQYMQNVVVKTLWKHQFAWPFYTPVDAIKLNLPDYHKVIKNPMDMGTIKKRLENNYYWTAGECMQDFNTMFTNCYIYNKPTDDIVLMAQALEKIFLQKVAQMP 137          

HSP 3 Score: 67.0106 bits (162), Expect = 7.251e-11
Identity = 29/75 (38.67%), Postives = 43/75 (57.33%), Query Frame = 2
Query:  665 FLEPVDVEGLKLHDYFDIVKKPMDLGTVKNKLFDGFYQSNDEFAEDIKLIFKNCYLYNPEGHEVNRCGKLLEDIF 889
            F  PVD   L L DY  ++K PMD+GT+K +L + +Y +  E  +D   +F NCY+YN    ++    + LE IF
Sbjct:   55 FYTPVDAIKLNLPDYHKVIKNPMDMGTIKKRLENNYYWTAGECMQDFNTMFTNCYIYNKPTDDIVLMAQALEKIF 129          

HSP 4 Score: 66.6254 bits (161), Expect = 1.022e-10
Identity = 33/83 (39.76%), Postives = 48/83 (57.83%), Query Frame = 2
Query:  110 FKVPVNPELLGIPNYPDIIKYPMDFGTIKIKLDKQVYQSANECKSDFLSVFRNCYIFNEPGSLYVDMALKLENLFKRKMTDLP 358
            F  PV+ E L + +Y +IIK PMD  T+K K+D + Y  A    +D   +F NCY +N P    V MA KL+++F+ K   +P
Sbjct:  317 FYKPVDAEALELHDYHEIIKQPMDLSTVKKKMDSREYPDAQNFAADVRLMFSNCYKYNPPDHEVVAMARKLQDVFEMKFAKMP 399          
BLAST of Bromodomain-containing protein 2 vs. Ensembl Zebrafish
Match: brd3a (bromodomain containing 3a [Source:ZFIN;Acc:ZDB-GENE-030131-6141])

HSP 1 Score: 107.071 bits (266), Expect = 2.944e-23
Identity = 49/105 (46.67%), Postives = 65/105 (61.90%), Query Frame = 2
Query:  575 KKSKLEIDIKICKHIILNLVSKKYGDLNRYFLEPVDVEGLKLHDYFDIVKKPMDLGTVKNKLFDGFYQSNDEFAEDIKLIFKNCYLYNPEGHEVNRCGKLLEDIF 889
            KK +L   +K C  I+  ++SKK+      F +PVD E L+LHDY DI+K PMDL TVK K+    YQ    FA D++L+F NCY YNP  HEV    + L+D+F
Sbjct:  288 KKGRLSEQLKYCDVILKEMLSKKHAAYAWPFYKPVDAEALELHDYHDIIKHPMDLSTVKKKMDSREYQDAQTFAADVRLMFSNCYKYNPPDHEVVAMARKLQDVF 392          

HSP 2 Score: 95.1301 bits (235), Expect = 1.852e-19
Identity = 47/106 (44.34%), Postives = 67/106 (63.21%), Query Frame = 2
Query:   41 TNQLLYIKKNVINVLLRNSNSESFKVPVNPELLGIPNYPDIIKYPMDFGTIKIKLDKQVYQSANECKSDFLSVFRNCYIFNEPGSLYVDMALKLENLFKRKMTDLP 358
            TNQL Y++  V+  L ++  +  F  PV+   LG+P+Y  IIK PMD GTIK +L+   Y SA+EC  DF ++F NCYI+N+P    V MA  LE +F +K+  +P
Sbjct:   32 TNQLQYMQNVVVKTLWKHQFAWPFYQPVDAVKLGLPDYHKIIKNPMDMGTIKKRLESVYYYSASECMQDFNTMFTNCYIYNKPTDDIVLMAQALEKIFLQKVALMP 137          

HSP 3 Score: 71.633 bits (174), Expect = 3.596e-12
Identity = 34/83 (40.96%), Postives = 50/83 (60.24%), Query Frame = 2
Query:  110 FKVPVNPELLGIPNYPDIIKYPMDFGTIKIKLDKQVYQSANECKSDFLSVFRNCYIFNEPGSLYVDMALKLENLFKRKMTDLP 358
            F  PV+ E L + +Y DIIK+PMD  T+K K+D + YQ A    +D   +F NCY +N P    V MA KL+++F+ +   +P
Sbjct:  318 FYKPVDAEALELHDYHDIIKHPMDLSTVKKKMDSREYQDAQTFAADVRLMFSNCYKYNPPDHEVVAMARKLQDVFEMRFAKMP 400          

HSP 4 Score: 68.5514 bits (166), Expect = 2.538e-11
Identity = 31/75 (41.33%), Postives = 43/75 (57.33%), Query Frame = 2
Query:  665 FLEPVDVEGLKLHDYFDIVKKPMDLGTVKNKLFDGFYQSNDEFAEDIKLIFKNCYLYNPEGHEVNRCGKLLEDIF 889
            F +PVD   L L DY  I+K PMD+GT+K +L   +Y S  E  +D   +F NCY+YN    ++    + LE IF
Sbjct:   55 FYQPVDAVKLGLPDYHKIIKNPMDMGTIKKRLESVYYYSASECMQDFNTMFTNCYIYNKPTDDIVLMAQALEKIF 129          
BLAST of Bromodomain-containing protein 2 vs. Ensembl Zebrafish
Match: brd4 (bromodomain containing 4 [Source:NCBI gene;Acc:570531])

HSP 1 Score: 105.916 bits (263), Expect = 1.312e-22
Identity = 49/123 (39.84%), Postives = 73/123 (59.35%), Query Frame = 2
Query:  521 KRVRSESNNGYTKEEPLFKKSKLEIDIKICKHIILNLVSKKYGDLNRYFLEPVDVEGLKLHDYFDIVKKPMDLGTVKNKLFDGFYQSNDEFAEDIKLIFKNCYLYNPEGHEVNRCGKLLEDIF 889
            K+   +S + +T   P     K +  ++ C  I+ ++ +KK+      F +PVDV+ L LHDY DI+K PMDL T+K+KL    Y+   EFA D++L+F NCY YNP  HEV    + L+D+F
Sbjct:  339 KKEAPDSQHHWTAA-PGTPSPKQQEQLRYCSGIVKDMFAKKHAAYAWPFYKPVDVDTLGLHDYHDIIKHPMDLSTIKDKLETRQYREAQEFAADVRLMFSNCYKYNPPDHEVVAMARKLQDVF 460          

HSP 2 Score: 96.2857 bits (238), Expect = 1.184e-19
Identity = 48/106 (45.28%), Postives = 67/106 (63.21%), Query Frame = 2
Query:   41 TNQLLYIKKNVINVLLRNSNSESFKVPVNPELLGIPNYPDIIKYPMDFGTIKIKLDKQVYQSANECKSDFLSVFRNCYIFNEPGSLYVDMALKLENLFKRKMTDLP 358
            TNQL Y+ K V+  L ++  +  F  PV+   L +P+Y  IIK PMD GTIK +L+   Y SA EC  DF ++F NCYI+N+PG   V MA  LE +F  K++++P
Sbjct:   45 TNQLQYLLKVVLKSLWKHQFAWPFHAPVDAVKLNLPDYYKIIKNPMDMGTIKKRLESAFYTSAQECIQDFNTMFTNCYIYNKPGDDIVLMAEALEKVFLTKISEMP 150          

HSP 3 Score: 75.0998 bits (183), Expect = 3.881e-13
Identity = 32/75 (42.67%), Postives = 44/75 (58.67%), Query Frame = 2
Query:  665 FLEPVDVEGLKLHDYFDIVKKPMDLGTVKNKLFDGFYQSNDEFAEDIKLIFKNCYLYNPEGHEVNRCGKLLEDIF 889
            F  PVD   L L DY+ I+K PMD+GT+K +L   FY S  E  +D   +F NCY+YN  G ++    + LE +F
Sbjct:   68 FHAPVDAVKLNLPDYYKIIKNPMDMGTIKKRLESAFYTSAQECIQDFNTMFTNCYIYNKPGDDIVLMAEALEKVF 142          

HSP 4 Score: 71.633 bits (174), Expect = 4.100e-12
Identity = 35/83 (42.17%), Postives = 52/83 (62.65%), Query Frame = 2
Query:  110 FKVPVNPELLGIPNYPDIIKYPMDFGTIKIKLDKQVYQSANECKSDFLSVFRNCYIFNEPGSLYVDMALKLENLFKRKMTDLP 358
            F  PV+ + LG+ +Y DIIK+PMD  TIK KL+ + Y+ A E  +D   +F NCY +N P    V MA KL+++F+ +   +P
Sbjct:  386 FYKPVDVDTLGLHDYHDIIKHPMDLSTIKDKLETRQYREAQEFAADVRLMFSNCYKYNPPDHEVVAMARKLQDVFEMRFAKMP 468          
BLAST of Bromodomain-containing protein 2 vs. Ensembl Xenopus
Match: kif3b (kinesin family member 3B [Source:Xenbase;Acc:XB-GENE-979232])

HSP 1 Score: 108.227 bits (269), Expect = 3.506e-23
Identity = 49/109 (44.95%), Postives = 67/109 (61.47%), Query Frame = 2
Query:  575 KKSKLEIDIKICKHIILNLVSKKYGDLNRYFLEPVDVEGLKLHDYFDIVKKPMDLGTVKNKLFDGFYQSNDEFAEDIKLIFKNCYLYNPEGHEVNRCGKLLEDIFNKLY 901
            K SK    ++ C  II  + SKK+      F +PVDV+ L LHDY +I+K PMDLGT+K K+ +  Y+   EFA D++L+F NCY YNP  HEV    + L+D+F   Y
Sbjct:  371 KDSKTSEQLRYCAGIIREMFSKKHQAYAWPFYKPVDVDALGLHDYREIIKHPMDLGTIKVKMDNWDYKDAKEFASDVRLMFSNCYKYNPPDHEVVIMARKLQDVFEMRY 479          

HSP 2 Score: 101.293 bits (251), Expect = 5.563e-21
Identity = 48/106 (45.28%), Postives = 70/106 (66.04%), Query Frame = 2
Query:   41 TNQLLYIKKNVINVLLRNSNSESFKVPVNPELLGIPNYPDIIKYPMDFGTIKIKLDKQVYQSANECKSDFLSVFRNCYIFNEPGSLYVDMALKLENLFKRKMTDLP 358
            TNQL Y+ K V+  L ++  +  F++PV+   L +P+Y  IIK PMD GTIK +L+   Y +A EC  DF ++F NCYI+N+PG   V MA  LE LF +K++++P
Sbjct:   62 TNQLQYLLKTVLKTLWKHQFAWPFQLPVDVVKLNLPDYHKIIKNPMDMGTIKKRLENHYYWNAQECIQDFNTMFTNCYIYNKPGDDIVLMAEALEKLFLQKISEMP 167          

HSP 3 Score: 74.7146 bits (182), Expect = 7.694e-13
Identity = 35/82 (42.68%), Postives = 52/82 (63.41%), Query Frame = 2
Query:  110 FKVPVNPELLGIPNYPDIIKYPMDFGTIKIKLDKQVYQSANECKSDFLSVFRNCYIFNEPGSLYVDMALKLENLFKRKMTDL 355
            F  PV+ + LG+ +Y +IIK+PMD GTIK+K+D   Y+ A E  SD   +F NCY +N P    V MA KL+++F+ +   +
Sbjct:  401 FYKPVDVDALGLHDYREIIKHPMDLGTIKVKMDNWDYKDAKEFASDVRLMFSNCYKYNPPDHEVVIMARKLQDVFEMRYAKM 482          

HSP 4 Score: 70.4774 bits (171), Expect = 1.265e-11
Identity = 31/75 (41.33%), Postives = 45/75 (60.00%), Query Frame = 2
Query:  665 FLEPVDVEGLKLHDYFDIVKKPMDLGTVKNKLFDGFYQSNDEFAEDIKLIFKNCYLYNPEGHEVNRCGKLLEDIF 889
            F  PVDV  L L DY  I+K PMD+GT+K +L + +Y +  E  +D   +F NCY+YN  G ++    + LE +F
Sbjct:   85 FQLPVDVVKLNLPDYHKIIKNPMDMGTIKKRLENHYYWNAQECIQDFNTMFTNCYIYNKPGDDIVLMAEALEKLF 159          
BLAST of Bromodomain-containing protein 2 vs. Ensembl Xenopus
Match: kif3b (kinesin family member 3B [Source:Xenbase;Acc:XB-GENE-979232])

HSP 1 Score: 108.227 bits (269), Expect = 3.516e-23
Identity = 49/109 (44.95%), Postives = 67/109 (61.47%), Query Frame = 2
Query:  575 KKSKLEIDIKICKHIILNLVSKKYGDLNRYFLEPVDVEGLKLHDYFDIVKKPMDLGTVKNKLFDGFYQSNDEFAEDIKLIFKNCYLYNPEGHEVNRCGKLLEDIFNKLY 901
            K SK    ++ C  II  + SKK+      F +PVDV+ L LHDY +I+K PMDLGT+K K+ +  Y+   EFA D++L+F NCY YNP  HEV    + L+D+F   Y
Sbjct:  371 KDSKTSEQLRYCAGIIREMFSKKHQAYAWPFYKPVDVDALGLHDYREIIKHPMDLGTIKVKMDNWDYKDAKEFASDVRLMFSNCYKYNPPDHEVVIMARKLQDVFEMRY 479          

HSP 2 Score: 101.293 bits (251), Expect = 5.624e-21
Identity = 48/106 (45.28%), Postives = 70/106 (66.04%), Query Frame = 2
Query:   41 TNQLLYIKKNVINVLLRNSNSESFKVPVNPELLGIPNYPDIIKYPMDFGTIKIKLDKQVYQSANECKSDFLSVFRNCYIFNEPGSLYVDMALKLENLFKRKMTDLP 358
            TNQL Y+ K V+  L ++  +  F++PV+   L +P+Y  IIK PMD GTIK +L+   Y +A EC  DF ++F NCYI+N+PG   V MA  LE LF +K++++P
Sbjct:   62 TNQLQYLLKTVLKTLWKHQFAWPFQLPVDVVKLNLPDYHKIIKNPMDMGTIKKRLENHYYWNAQECIQDFNTMFTNCYIYNKPGDDIVLMAEALEKLFLQKISEMP 167          

HSP 3 Score: 74.7146 bits (182), Expect = 7.139e-13
Identity = 35/82 (42.68%), Postives = 52/82 (63.41%), Query Frame = 2
Query:  110 FKVPVNPELLGIPNYPDIIKYPMDFGTIKIKLDKQVYQSANECKSDFLSVFRNCYIFNEPGSLYVDMALKLENLFKRKMTDL 355
            F  PV+ + LG+ +Y +IIK+PMD GTIK+K+D   Y+ A E  SD   +F NCY +N P    V MA KL+++F+ +   +
Sbjct:  401 FYKPVDVDALGLHDYREIIKHPMDLGTIKVKMDNWDYKDAKEFASDVRLMFSNCYKYNPPDHEVVIMARKLQDVFEMRYAKM 482          

HSP 4 Score: 70.4774 bits (171), Expect = 1.344e-11
Identity = 31/75 (41.33%), Postives = 45/75 (60.00%), Query Frame = 2
Query:  665 FLEPVDVEGLKLHDYFDIVKKPMDLGTVKNKLFDGFYQSNDEFAEDIKLIFKNCYLYNPEGHEVNRCGKLLEDIF 889
            F  PVDV  L L DY  I+K PMD+GT+K +L + +Y +  E  +D   +F NCY+YN  G ++    + LE +F
Sbjct:   85 FQLPVDVVKLNLPDYHKIIKNPMDMGTIKKRLENHYYWNAQECIQDFNTMFTNCYIYNKPGDDIVLMAEALEKLF 159          
BLAST of Bromodomain-containing protein 2 vs. Ensembl Xenopus
Match: brd3 (bromodomain containing 3 [Source:NCBI gene;Acc:733891])

HSP 1 Score: 107.071 bits (266), Expect = 5.533e-23
Identity = 49/105 (46.67%), Postives = 64/105 (60.95%), Query Frame = 2
Query:  575 KKSKLEIDIKICKHIILNLVSKKYGDLNRYFLEPVDVEGLKLHDYFDIVKKPMDLGTVKNKLFDGFYQSNDEFAEDIKLIFKNCYLYNPEGHEVNRCGKLLEDIF 889
            KK KL   +K C  I+  ++SKK+      F +PVD E L+LHDY DI+K PMDL +VK K+    Y     FA DI+L+F NCY YNP  HEV    + L+D+F
Sbjct:  356 KKGKLNEHLKYCDSILKEMLSKKHAAYAWPFYKPVDAEALELHDYHDIIKHPMDLSSVKRKMDAREYADAQAFAADIRLMFSNCYKYNPPDHEVVAMARKLQDVF 460          

HSP 2 Score: 92.4337 bits (228), Expect = 1.975e-18
Identity = 46/106 (43.40%), Postives = 65/106 (61.32%), Query Frame = 2
Query:   41 TNQLLYIKKNVINVLLRNSNSESFKVPVNPELLGIPNYPDIIKYPMDFGTIKIKLDKQVYQSANECKSDFLSVFRNCYIFNEPGSLYVDMALKLENLFKRKMTDLP 358
            TNQL Y++  V+  L ++  +  F  PV+   L +P+Y  IIK PMD GTIK +L+   Y SANEC  DF ++F NCYI+N+     V MA  LE +F +K+  +P
Sbjct:   32 TNQLQYMQNVVVKTLWKHQFAWPFYQPVDCVKLNLPDYHKIIKNPMDMGTIKKRLENNYYWSANECMQDFNTMFTNCYIYNKSTDDIVLMAQALEKIFLQKVAQMP 137          

HSP 3 Score: 71.633 bits (174), Expect = 5.116e-12
Identity = 31/75 (41.33%), Postives = 45/75 (60.00%), Query Frame = 2
Query:  665 FLEPVDVEGLKLHDYFDIVKKPMDLGTVKNKLFDGFYQSNDEFAEDIKLIFKNCYLYNPEGHEVNRCGKLLEDIF 889
            F +PVD   L L DY  I+K PMD+GT+K +L + +Y S +E  +D   +F NCY+YN    ++    + LE IF
Sbjct:   55 FYQPVDCVKLNLPDYHKIIKNPMDMGTIKKRLENNYYWSANECMQDFNTMFTNCYIYNKSTDDIVLMAQALEKIF 129          

HSP 4 Score: 70.4774 bits (171), Expect = 1.298e-11
Identity = 32/83 (38.55%), Postives = 49/83 (59.04%), Query Frame = 2
Query:  110 FKVPVNPELLGIPNYPDIIKYPMDFGTIKIKLDKQVYQSANECKSDFLSVFRNCYIFNEPGSLYVDMALKLENLFKRKMTDLP 358
            F  PV+ E L + +Y DIIK+PMD  ++K K+D + Y  A    +D   +F NCY +N P    V MA KL+++F+ +   +P
Sbjct:  386 FYKPVDAEALELHDYHDIIKHPMDLSSVKRKMDAREYADAQAFAADIRLMFSNCYKYNPPDHEVVAMARKLQDVFEMRFAKMP 468          
BLAST of Bromodomain-containing protein 2 vs. Ensembl Xenopus
Match: brd2 (bromodomain containing 2 [Source:NCBI gene;Acc:100038037])

HSP 1 Score: 106.301 bits (264), Expect = 8.697e-23
Identity = 48/109 (44.04%), Postives = 67/109 (61.47%), Query Frame = 2
Query:  575 KKSKLEIDIKICKHIILNLVSKKYGDLNRYFLEPVDVEGLKLHDYFDIVKKPMDLGTVKNKLFDGFYQSNDEFAEDIKLIFKNCYLYNPEGHEVNRCGKLLEDIFNKLY 901
            KK KL   +K C  I+  L+SKK+      F +PVDV  L LHDY+DI+K PMDL T+K K+ +  ++   EFA  ++L+F NCY YNP  H+V    + L+D+F   Y
Sbjct:  313 KKGKLSEQLKYCNGILKELLSKKHAAYAWPFYKPVDVSALGLHDYYDIIKHPMDLSTIKKKMDNREFKDAQEFAAAVRLMFSNCYKYNPPDHDVVAMARKLQDVFEFRY 421          

HSP 2 Score: 68.1662 bits (165), Expect = 6.120e-11
Identity = 33/83 (39.76%), Postives = 50/83 (60.24%), Query Frame = 2
Query:  110 FKVPVNPELLGIPNYPDIIKYPMDFGTIKIKLDKQVYQSANECKSDFLSVFRNCYIFNEPGSLYVDMALKLENLFKRKMTDLP 358
            F  PV+   LG+ +Y DIIK+PMD  TIK K+D + ++ A E  +    +F NCY +N P    V MA KL+++F+ +   +P
Sbjct:  343 FYKPVDVSALGLHDYYDIIKHPMDLSTIKKKMDNREFKDAQEFAAAVRLMFSNCYKYNPPDHDVVAMARKLQDVFEFRYAKMP 425          
BLAST of Bromodomain-containing protein 2 vs. Ensembl Xenopus
Match: brd2 (bromodomain containing 2 [Source:NCBI gene;Acc:100038037])

HSP 1 Score: 106.301 bits (264), Expect = 9.652e-23
Identity = 48/109 (44.04%), Postives = 67/109 (61.47%), Query Frame = 2
Query:  575 KKSKLEIDIKICKHIILNLVSKKYGDLNRYFLEPVDVEGLKLHDYFDIVKKPMDLGTVKNKLFDGFYQSNDEFAEDIKLIFKNCYLYNPEGHEVNRCGKLLEDIFNKLY 901
            KK KL   +K C  I+  L+SKK+      F +PVDV  L LHDY+DI+K PMDL T+K K+ +  ++   EFA  ++L+F NCY YNP  H+V    + L+D+F   Y
Sbjct:  336 KKGKLSEQLKYCNGILKELLSKKHAAYAWPFYKPVDVSALGLHDYYDIIKHPMDLSTIKKKMDNREFKDAQEFAAAVRLMFSNCYKYNPPDHDVVAMARKLQDVFEFRY 444          

HSP 2 Score: 100.138 bits (248), Expect = 8.592e-21
Identity = 50/116 (43.10%), Postives = 71/116 (61.21%), Query Frame = 2
Query:   41 TNQLLYIKKNVINVLLRNSNSESFKVPVNPELLGIPNYPDIIKYPMDFGTIKIKLDKQVYQSANECKSDFLSVFRNCYIFNEPGSLYVDMALKLENLFKRKMTDLPVPEHYVQDST 388
            TNQL Y+ K V+  L ++  S  F+ PV+   LG+P+Y  IIK PMD GTIK +L+   Y SA EC  DF ++F NCYI+N+P    V MA  LE +F +K+  +P  E  + ++ 
Sbjct:   76 TNQLQYLHKVVMKSLWKHQFSWPFRQPVDAVKLGLPDYHKIIKQPMDMGTIKKRLENNYYWSALECMQDFNTMFTNCYIYNKPTDDIVLMAQSLEKMFLQKVAQMPQEEQEIPNTA 191          

HSP 3 Score: 68.5514 bits (166), Expect = 4.818e-11
Identity = 30/75 (40.00%), Postives = 45/75 (60.00%), Query Frame = 2
Query:  665 FLEPVDVEGLKLHDYFDIVKKPMDLGTVKNKLFDGFYQSNDEFAEDIKLIFKNCYLYNPEGHEVNRCGKLLEDIF 889
            F +PVD   L L DY  I+K+PMD+GT+K +L + +Y S  E  +D   +F NCY+YN    ++    + LE +F
Sbjct:   99 FRQPVDAVKLGLPDYHKIIKQPMDMGTIKKRLENNYYWSALECMQDFNTMFTNCYIYNKPTDDIVLMAQSLEKMF 173          

HSP 4 Score: 68.1662 bits (165), Expect = 6.441e-11
Identity = 33/83 (39.76%), Postives = 50/83 (60.24%), Query Frame = 2
Query:  110 FKVPVNPELLGIPNYPDIIKYPMDFGTIKIKLDKQVYQSANECKSDFLSVFRNCYIFNEPGSLYVDMALKLENLFKRKMTDLP 358
            F  PV+   LG+ +Y DIIK+PMD  TIK K+D + ++ A E  +    +F NCY +N P    V MA KL+++F+ +   +P
Sbjct:  366 FYKPVDVSALGLHDYYDIIKHPMDLSTIKKKMDNREFKDAQEFAAAVRLMFSNCYKYNPPDHDVVAMARKLQDVFEFRYAKMP 448          
BLAST of Bromodomain-containing protein 2 vs. Ensembl Mouse
Match: Brd4 (bromodomain containing 4 [Source:MGI Symbol;Acc:MGI:1888520])

HSP 1 Score: 109.383 bits (272), Expect = 1.389e-23
Identity = 47/105 (44.76%), Postives = 65/105 (61.90%), Query Frame = 2
Query:  575 KKSKLEIDIKICKHIILNLVSKKYGDLNRYFLEPVDVEGLKLHDYFDIVKKPMDLGTVKNKLFDGFYQSNDEFAEDIKLIFKNCYLYNPEGHEVNRCGKLLEDIF 889
            K SK+   +K C  I+  + +KK+      F +PVDVE L LHDY DI+K PMD+ T+K+KL    Y+   EF  D++L+F NCY YNP  HEV    + L+D+F
Sbjct:  348 KSSKISEQLKCCSGILKEMFAKKHAAYAWPFYKPVDVEALGLHDYCDIIKHPMDMSTIKSKLESREYRDAQEFGADVRLMFSNCYKYNPPDHEVVAMARKLQDVF 452          

HSP 2 Score: 97.8265 bits (242), Expect = 4.787e-20
Identity = 49/109 (44.95%), Postives = 69/109 (63.30%), Query Frame = 2
Query:   41 TNQLLYIKKNVINVLLRNSNSESFKVPVNPELLGIPNYPDIIKYPMDFGTIKIKLDKQVYQSANECKSDFLSVFRNCYIFNEPGSLYVDMALKLENLFKRKMTDLPVPE 367
            TNQL Y+ + V+  L ++  +  F+ PV+   L +P+Y  IIK PMD GTIK +L+   Y +A EC  DF ++F NCYI+N+PG   V MA  LE LF +K+ +LP  E
Sbjct:   60 TNQLQYLLRVVLKTLWKHQFAWPFQQPVDAVKLNLPDYYKIIKTPMDMGTIKKRLENNYYWNAQECIQDFNTMFTNCYIYNKPGDDIVLMAEALEKLFLQKINELPTEE 168          

HSP 3 Score: 74.7146 bits (182), Expect = 5.005e-13
Identity = 36/83 (43.37%), Postives = 52/83 (62.65%), Query Frame = 2
Query:  110 FKVPVNPELLGIPNYPDIIKYPMDFGTIKIKLDKQVYQSANECKSDFLSVFRNCYIFNEPGSLYVDMALKLENLFKRKMTDLP 358
            F  PV+ E LG+ +Y DIIK+PMD  TIK KL+ + Y+ A E  +D   +F NCY +N P    V MA KL+++F+ +   +P
Sbjct:  378 FYKPVDVEALGLHDYCDIIKHPMDMSTIKSKLESREYRDAQEFGADVRLMFSNCYKYNPPDHEVVAMARKLQDVFEMRFAKMP 460          

HSP 4 Score: 73.1738 bits (178), Expect = 1.756e-12
Identity = 30/75 (40.00%), Postives = 46/75 (61.33%), Query Frame = 2
Query:  665 FLEPVDVEGLKLHDYFDIVKKPMDLGTVKNKLFDGFYQSNDEFAEDIKLIFKNCYLYNPEGHEVNRCGKLLEDIF 889
            F +PVD   L L DY+ I+K PMD+GT+K +L + +Y +  E  +D   +F NCY+YN  G ++    + LE +F
Sbjct:   83 FQQPVDAVKLNLPDYYKIIKTPMDMGTIKKRLENNYYWNAQECIQDFNTMFTNCYIYNKPGDDIVLMAEALEKLF 157          

HSP 5 Score: 53.1434 bits (126), Expect = 1.972e-6
Identity = 32/90 (35.56%), Postives = 51/90 (56.67%), Query Frame = 2
Query: 1805 ESKSDLKEFTIEDRMQLSQDL-RLLGDKCSEKILNIYKKTEDVQSSDG-ECEIDFQTMKLVTLHSLREFADKCLQKKREKQLKKCAVTAG 2068
            E +   K  + E++ QLS D+ +L G+K    +  I  +   +++S+  E EIDF+T+K  TL  L  +   CL+KKR+ Q +K  V AG
Sbjct:  604 EEEDKCKPMSYEEKRQLSLDINKLPGEKLGRVVHIIQSREPSLKNSNPDEIEIDFETLKPSTLRELERYVTSCLRKKRKPQAEKVDVIAG 693          
BLAST of Bromodomain-containing protein 2 vs. Ensembl Mouse
Match: Brd4 (bromodomain containing 4 [Source:MGI Symbol;Acc:MGI:1888520])

HSP 1 Score: 109.383 bits (272), Expect = 1.436e-23
Identity = 47/105 (44.76%), Postives = 65/105 (61.90%), Query Frame = 2
Query:  575 KKSKLEIDIKICKHIILNLVSKKYGDLNRYFLEPVDVEGLKLHDYFDIVKKPMDLGTVKNKLFDGFYQSNDEFAEDIKLIFKNCYLYNPEGHEVNRCGKLLEDIF 889
            K SK+   +K C  I+  + +KK+      F +PVDVE L LHDY DI+K PMD+ T+K+KL    Y+   EF  D++L+F NCY YNP  HEV    + L+D+F
Sbjct:  347 KSSKISEQLKCCSGILKEMFAKKHAAYAWPFYKPVDVEALGLHDYCDIIKHPMDMSTIKSKLESREYRDAQEFGADVRLMFSNCYKYNPPDHEVVAMARKLQDVF 451          

HSP 2 Score: 97.8265 bits (242), Expect = 4.745e-20
Identity = 48/107 (44.86%), Postives = 68/107 (63.55%), Query Frame = 2
Query:   41 TNQLLYIKKNVINVLLRNSNSESFKVPVNPELLGIPNYPDIIKYPMDFGTIKIKLDKQVYQSANECKSDFLSVFRNCYIFNEPGSLYVDMALKLENLFKRKMTDLPV 361
            TNQL Y+ + V+  L ++  +  F+ PV+   L +P+Y  IIK PMD GTIK +L+   Y +A EC  DF ++F NCYI+N+PG   V MA  LE LF +K+ +LP 
Sbjct:   60 TNQLQYLLRVVLKTLWKHQFAWPFQQPVDAVKLNLPDYYKIIKTPMDMGTIKKRLENNYYWNAQECIQDFNTMFTNCYIYNKPGDDIVLMAEALEKLFLQKINELPT 166          

HSP 3 Score: 74.7146 bits (182), Expect = 4.920e-13
Identity = 36/83 (43.37%), Postives = 52/83 (62.65%), Query Frame = 2
Query:  110 FKVPVNPELLGIPNYPDIIKYPMDFGTIKIKLDKQVYQSANECKSDFLSVFRNCYIFNEPGSLYVDMALKLENLFKRKMTDLP 358
            F  PV+ E LG+ +Y DIIK+PMD  TIK KL+ + Y+ A E  +D   +F NCY +N P    V MA KL+++F+ +   +P
Sbjct:  377 FYKPVDVEALGLHDYCDIIKHPMDMSTIKSKLESREYRDAQEFGADVRLMFSNCYKYNPPDHEVVAMARKLQDVFEMRFAKMP 459          

HSP 4 Score: 73.1738 bits (178), Expect = 1.756e-12
Identity = 30/75 (40.00%), Postives = 46/75 (61.33%), Query Frame = 2
Query:  665 FLEPVDVEGLKLHDYFDIVKKPMDLGTVKNKLFDGFYQSNDEFAEDIKLIFKNCYLYNPEGHEVNRCGKLLEDIF 889
            F +PVD   L L DY+ I+K PMD+GT+K +L + +Y +  E  +D   +F NCY+YN  G ++    + LE +F
Sbjct:   83 FQQPVDAVKLNLPDYYKIIKTPMDMGTIKKRLENNYYWNAQECIQDFNTMFTNCYIYNKPGDDIVLMAEALEKLF 157          

HSP 5 Score: 53.5286 bits (127), Expect = 1.874e-6
Identity = 32/90 (35.56%), Postives = 51/90 (56.67%), Query Frame = 2
Query: 1805 ESKSDLKEFTIEDRMQLSQDL-RLLGDKCSEKILNIYKKTEDVQSSDG-ECEIDFQTMKLVTLHSLREFADKCLQKKREKQLKKCAVTAG 2068
            E +   K  + E++ QLS D+ +L G+K    +  I  +   +++S+  E EIDF+T+K  TL  L  +   CL+KKR+ Q +K  V AG
Sbjct:  603 EEEDKCKPMSYEEKRQLSLDINKLPGEKLGRVVHIIQSREPSLKNSNPDEIEIDFETLKPSTLRELERYVTSCLRKKRKPQAEKVDVIAG 692          
BLAST of Bromodomain-containing protein 2 vs. Ensembl Mouse
Match: Brd4 (bromodomain containing 4 [Source:MGI Symbol;Acc:MGI:1888520])

HSP 1 Score: 107.071 bits (266), Expect = 1.922e-23
Identity = 47/105 (44.76%), Postives = 65/105 (61.90%), Query Frame = 2
Query:  575 KKSKLEIDIKICKHIILNLVSKKYGDLNRYFLEPVDVEGLKLHDYFDIVKKPMDLGTVKNKLFDGFYQSNDEFAEDIKLIFKNCYLYNPEGHEVNRCGKLLEDIF 889
            K SK+   +K C  I+  + +KK+      F +PVDVE L LHDY DI+K PMD+ T+K+KL    Y+   EF  D++L+F NCY YNP  HEV    + L+D+F
Sbjct:  347 KSSKISEQLKCCSGILKEMFAKKHAAYAWPFYKPVDVEALGLHDYCDIIKHPMDMSTIKSKLESREYRDAQEFGADVRLMFSNCYKYNPPDHEVVAMARKLQDVF 451          

HSP 2 Score: 97.0561 bits (240), Expect = 3.259e-20
Identity = 49/109 (44.95%), Postives = 69/109 (63.30%), Query Frame = 2
Query:   41 TNQLLYIKKNVINVLLRNSNSESFKVPVNPELLGIPNYPDIIKYPMDFGTIKIKLDKQVYQSANECKSDFLSVFRNCYIFNEPGSLYVDMALKLENLFKRKMTDLPVPE 367
            TNQL Y+ + V+  L ++  +  F+ PV+   L +P+Y  IIK PMD GTIK +L+   Y +A EC  DF ++F NCYI+N+PG   V MA  LE LF +K+ +LP  E
Sbjct:   60 TNQLQYLLRVVLKTLWKHQFAWPFQQPVDAVKLNLPDYYKIIKTPMDMGTIKKRLENNYYWNAQECIQDFNTMFTNCYIYNKPGDDIVLMAEALEKLFLQKINELPTEE 168          

HSP 3 Score: 73.1738 bits (178), Expect = 9.265e-13
Identity = 36/83 (43.37%), Postives = 52/83 (62.65%), Query Frame = 2
Query:  110 FKVPVNPELLGIPNYPDIIKYPMDFGTIKIKLDKQVYQSANECKSDFLSVFRNCYIFNEPGSLYVDMALKLENLFKRKMTDLP 358
            F  PV+ E LG+ +Y DIIK+PMD  TIK KL+ + Y+ A E  +D   +F NCY +N P    V MA KL+++F+ +   +P
Sbjct:  377 FYKPVDVEALGLHDYCDIIKHPMDMSTIKSKLESREYRDAQEFGADVRLMFSNCYKYNPPDHEVVAMARKLQDVFEMRFAKMP 459          

HSP 4 Score: 72.0182 bits (175), Expect = 2.107e-12
Identity = 30/75 (40.00%), Postives = 46/75 (61.33%), Query Frame = 2
Query:  665 FLEPVDVEGLKLHDYFDIVKKPMDLGTVKNKLFDGFYQSNDEFAEDIKLIFKNCYLYNPEGHEVNRCGKLLEDIF 889
            F +PVD   L L DY+ I+K PMD+GT+K +L + +Y +  E  +D   +F NCY+YN  G ++    + LE +F
Sbjct:   83 FQQPVDAVKLNLPDYYKIIKTPMDMGTIKKRLENNYYWNAQECIQDFNTMFTNCYIYNKPGDDIVLMAEALEKLF 157          
BLAST of Bromodomain-containing protein 2 vs. Ensembl Mouse
Match: Brd4 (bromodomain containing 4 [Source:MGI Symbol;Acc:MGI:1888520])

HSP 1 Score: 107.071 bits (266), Expect = 1.987e-23
Identity = 47/105 (44.76%), Postives = 65/105 (61.90%), Query Frame = 2
Query:  575 KKSKLEIDIKICKHIILNLVSKKYGDLNRYFLEPVDVEGLKLHDYFDIVKKPMDLGTVKNKLFDGFYQSNDEFAEDIKLIFKNCYLYNPEGHEVNRCGKLLEDIF 889
            K SK+   +K C  I+  + +KK+      F +PVDVE L LHDY DI+K PMD+ T+K+KL    Y+   EF  D++L+F NCY YNP  HEV    + L+D+F
Sbjct:  347 KSSKISEQLKCCSGILKEMFAKKHAAYAWPFYKPVDVEALGLHDYCDIIKHPMDMSTIKSKLESREYRDAQEFGADVRLMFSNCYKYNPPDHEVVAMARKLQDVF 451          

HSP 2 Score: 96.6709 bits (239), Expect = 3.865e-20
Identity = 49/109 (44.95%), Postives = 69/109 (63.30%), Query Frame = 2
Query:   41 TNQLLYIKKNVINVLLRNSNSESFKVPVNPELLGIPNYPDIIKYPMDFGTIKIKLDKQVYQSANECKSDFLSVFRNCYIFNEPGSLYVDMALKLENLFKRKMTDLPVPE 367
            TNQL Y+ + V+  L ++  +  F+ PV+   L +P+Y  IIK PMD GTIK +L+   Y +A EC  DF ++F NCYI+N+PG   V MA  LE LF +K+ +LP  E
Sbjct:   60 TNQLQYLLRVVLKTLWKHQFAWPFQQPVDAVKLNLPDYYKIIKTPMDMGTIKKRLENNYYWNAQECIQDFNTMFTNCYIYNKPGDDIVLMAEALEKLFLQKINELPTEE 168          

HSP 3 Score: 73.1738 bits (178), Expect = 9.635e-13
Identity = 36/83 (43.37%), Postives = 52/83 (62.65%), Query Frame = 2
Query:  110 FKVPVNPELLGIPNYPDIIKYPMDFGTIKIKLDKQVYQSANECKSDFLSVFRNCYIFNEPGSLYVDMALKLENLFKRKMTDLP 358
            F  PV+ E LG+ +Y DIIK+PMD  TIK KL+ + Y+ A E  +D   +F NCY +N P    V MA KL+++F+ +   +P
Sbjct:  377 FYKPVDVEALGLHDYCDIIKHPMDMSTIKSKLESREYRDAQEFGADVRLMFSNCYKYNPPDHEVVAMARKLQDVFEMRFAKMP 459          

HSP 4 Score: 72.0182 bits (175), Expect = 2.208e-12
Identity = 30/75 (40.00%), Postives = 46/75 (61.33%), Query Frame = 2
Query:  665 FLEPVDVEGLKLHDYFDIVKKPMDLGTVKNKLFDGFYQSNDEFAEDIKLIFKNCYLYNPEGHEVNRCGKLLEDIF 889
            F +PVD   L L DY+ I+K PMD+GT+K +L + +Y +  E  +D   +F NCY+YN  G ++    + LE +F
Sbjct:   83 FQQPVDAVKLNLPDYYKIIKTPMDMGTIKKRLENNYYWNAQECIQDFNTMFTNCYIYNKPGDDIVLMAEALEKLF 157          
BLAST of Bromodomain-containing protein 2 vs. Ensembl Mouse
Match: Brd4 (bromodomain containing 4 [Source:MGI Symbol;Acc:MGI:1888520])

HSP 1 Score: 107.457 bits (267), Expect = 3.021e-23
Identity = 47/105 (44.76%), Postives = 65/105 (61.90%), Query Frame = 2
Query:  575 KKSKLEIDIKICKHIILNLVSKKYGDLNRYFLEPVDVEGLKLHDYFDIVKKPMDLGTVKNKLFDGFYQSNDEFAEDIKLIFKNCYLYNPEGHEVNRCGKLLEDIF 889
            K SK+   +K C  I+  + +KK+      F +PVDVE L LHDY DI+K PMD+ T+K+KL    Y+   EF  D++L+F NCY YNP  HEV    + L+D+F
Sbjct:  347 KSSKISEQLKCCSGILKEMFAKKHAAYAWPFYKPVDVEALGLHDYCDIIKHPMDMSTIKSKLESREYRDAQEFGADVRLMFSNCYKYNPPDHEVVAMARKLQDVF 451          

HSP 2 Score: 98.2117 bits (243), Expect = 2.291e-20
Identity = 49/109 (44.95%), Postives = 69/109 (63.30%), Query Frame = 2
Query:   41 TNQLLYIKKNVINVLLRNSNSESFKVPVNPELLGIPNYPDIIKYPMDFGTIKIKLDKQVYQSANECKSDFLSVFRNCYIFNEPGSLYVDMALKLENLFKRKMTDLPVPE 367
            TNQL Y+ + V+  L ++  +  F+ PV+   L +P+Y  IIK PMD GTIK +L+   Y +A EC  DF ++F NCYI+N+PG   V MA  LE LF +K+ +LP  E
Sbjct:   60 TNQLQYLLRVVLKTLWKHQFAWPFQQPVDAVKLNLPDYYKIIKTPMDMGTIKKRLENNYYWNAQECIQDFNTMFTNCYIYNKPGDDIVLMAEALEKLFLQKINELPTEE 168          

HSP 3 Score: 74.7146 bits (182), Expect = 3.803e-13
Identity = 36/83 (43.37%), Postives = 52/83 (62.65%), Query Frame = 2
Query:  110 FKVPVNPELLGIPNYPDIIKYPMDFGTIKIKLDKQVYQSANECKSDFLSVFRNCYIFNEPGSLYVDMALKLENLFKRKMTDLP 358
            F  PV+ E LG+ +Y DIIK+PMD  TIK KL+ + Y+ A E  +D   +F NCY +N P    V MA KL+++F+ +   +P
Sbjct:  377 FYKPVDVEALGLHDYCDIIKHPMDMSTIKSKLESREYRDAQEFGADVRLMFSNCYKYNPPDHEVVAMARKLQDVFEMRFAKMP 459          

HSP 4 Score: 72.4034 bits (176), Expect = 2.003e-12
Identity = 30/75 (40.00%), Postives = 46/75 (61.33%), Query Frame = 2
Query:  665 FLEPVDVEGLKLHDYFDIVKKPMDLGTVKNKLFDGFYQSNDEFAEDIKLIFKNCYLYNPEGHEVNRCGKLLEDIF 889
            F +PVD   L L DY+ I+K PMD+GT+K +L + +Y +  E  +D   +F NCY+YN  G ++    + LE +F
Sbjct:   83 FQQPVDAVKLNLPDYYKIIKTPMDMGTIKKRLENNYYWNAQECIQDFNTMFTNCYIYNKPGDDIVLMAEALEKLF 157          

HSP 5 Score: 51.9878 bits (123), Expect = 4.327e-6
Identity = 32/90 (35.56%), Postives = 51/90 (56.67%), Query Frame = 2
Query: 1805 ESKSDLKEFTIEDRMQLSQDL-RLLGDKCSEKILNIYKKTEDVQSSD-GECEIDFQTMKLVTLHSLREFADKCLQKKREKQLKKCAVTAG 2068
            E +   K  + E++ QLS D+ +L G+K    +  I  +   +++S+  E EIDF+T+K  TL  L  +   CL+KKR+ Q +K  V AG
Sbjct:  603 EEEDKCKPMSYEEKRQLSLDINKLPGEKLGRVVHIIQSREPSLKNSNPDEIEIDFETLKPSTLRELERYVTSCLRKKRKPQAEKVDVIAG 692          
BLAST of Bromodomain-containing protein 2 vs. UniProt/SwissProt
Match: sp|Q07442|BDF2_YEAST (Bromodomain-containing factor 2 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) OX=559292 GN=BDF2 PE=1 SV=1)

HSP 1 Score: 144.05 bits (362), Expect = 2.733e-34
Identity = 93/279 (33.33%), Postives = 148/279 (53.05%), Query Frame = 2
Query:   89 RNSNSESFKVPVNPELLGIPNYPDIIKYPMDFGTIKIKLDKQVYQSANECKSDFLSVFRNCYIFNEPGSLYVDMALKLENLFKRKMTDLP---VPEHYVQDSTFHTPXXXXXXXXXXXXFHTPNVKPNRLTGNTMNSIAKSDISINQKRVRSESNNGYTKEEPLF--------KKSKLEIDIKICKHIILNLVSKKYGDLNRYFLEPVDVEGLKLHDYFDIVKKPMDLGTVKNKLFDGFYQSNDEFAEDIKLIFKNCYLYNPEGHEVNRCGKLLEDIFN 892
            R  ++  F  PV+P  L IP+Y + ++ PMD   I+ KL   VY S  +  SDF ++  NC  FN P S    MA +++  F++K++ +P   +P   ++ ++          + K+    +P V   R    T ++I +S         R +      K + LF        K   L+   + C  I+  L+SKK  D+N  FL+PVD   L L +YFD+VK PMDLGT+ N L +  Y++ D+F +D+ L+F NC+ +NPEG+EV+  GK L+++FN
Sbjct:  151 RLKDARPFLKPVDPIALNIPHYFNYVQTPMDLSLIETKLQGNVYHSVEQVTSDFKTMVDNCLNFNGPESSISSMAKRIQKYFEKKLSAMPPRVLPASALKKTS--------RNRKKNEDMDSPLV-IRRSVSTTNDNIGESGNREGVSGGRPKRTIHPPKSKDLFDIYENSKPKSKTLQKKFRTCLKILKVLMSKKNSDINFPFLQPVDPIALNLPNYFDVVKNPMDLGTISNNLMNWKYKTIDQFVDDLNLVFYNCFQFNPEGNEVHSMGKKLKELFN 420          

HSP 2 Score: 62.3882 bits (150), Expect = 1.660e-8
Identity = 35/91 (38.46%), Postives = 50/91 (54.95%), Query Frame = 2
Query:   71 VINVLLRNSNSE---SFKVPVNPELLGIPNYPDIIKYPMDFGTIKIKLDKQVYQSANECKSDFLSVFRNCYIFNEPGSLYVDMALKLENLF 334
            ++ VL+   NS+    F  PV+P  L +PNY D++K PMD GTI   L    Y++ ++   D   VF NC+ FN  G+    M  KL+ LF
Sbjct:  329 ILKVLMSKKNSDINFPFLQPVDPIALNLPNYFDVVKNPMDLGTISNNLMNWKYKTIDQFVDDLNLVFYNCFQFNPEGNEVHSMGKKLKELF 419          
BLAST of Bromodomain-containing protein 2 vs. UniProt/SwissProt
Match: sp|Q5A4W8|BDF1_CANAL (Bromodomain-containing factor 1 OS=Candida albicans (strain SC5314 / ATCC MYA-2876) OX=237561 GN=BDF1 PE=1 SV=1)

HSP 1 Score: 142.124 bits (357), Expect = 2.031e-33
Identity = 88/286 (30.77%), Postives = 147/286 (51.40%), Query Frame = 2
Query:   68 NVINVLLRNSNSESFKVPVNPELLGIPNYPDIIKYPMDFGTIKIKLDKQVYQSANECKSDFLSVFRNCYIFNEPGSLYVDMALKLENLFKRKMT-----DLPVPEHYVQDSTFHTPXXXXXXXXXXXXFHTPNVKPNRLTGNTMNSIAKSDISINQKRVRSESNNGYTKEEPLF---KKSKLEIDIKICKHIILNLVSKKYGDLNRYFLEPVDVEGLKLHDYFDIVKKPMDLGTVKNKLFDGFYQSNDEFAEDIKLIFKNCYLYNPEGHEVNRCGKLLEDIFNKLY 901
            N I  + RN  +  F  PV+   L +P Y + I  PMD  TI+ K++ + Y+  ++   DF  + +NC  FN   +    MA  ++  F++ M      +LP   +  + ++  T               +P     +    + +S    D S+   R +   +   +KE P     K  K+  +++ C   I  L+SKK+ + N  FL PVD   L + +Y +IVK+PMDLGT+++KL +  Y++ D+F +D++L+FKNCYL+NPEG +VN  G  LE +F+K +
Sbjct:  220 NTIKAVKRNREAVPFLHPVDTVKLNVPFYYNYIPRPMDLSTIERKINLKAYEDVSQVVDDFNLMVKNCKKFNGEAAGISKMATNIQAQFEKLMVKVPPKELPAGTNVAEATSVAT---------------SPTTNKRKSVAESSSSHQHRD-SVAAARPKRTIHPPKSKELPYETKPKNKKVAAELRFCNQTIKELMSKKHYNYNFPFLAPVDTVALNIPNYNEIVKQPMDLGTIQSKLANNEYENADDFEKDVRLVFKNCYLFNPEGTDVNMMGHRLEAVFDKKW 489          
BLAST of Bromodomain-containing protein 2 vs. UniProt/SwissProt
Match: sp|P35817|BDF1_YEAST (Bromodomain-containing factor 1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) OX=559292 GN=BDF1 PE=1 SV=3)

HSP 1 Score: 141.354 bits (355), Expect = 3.039e-33
Identity = 89/277 (32.13%), Postives = 137/277 (49.46%), Query Frame = 2
Query:   71 VINVLLRNSNSESFKVPVNPELLGIPNYPDIIKYPMDFGTIKIKLDKQVYQSANECKSDFLSVFRNCYIFNEPGSLYVDMALKLENLFKRKMTDLPVPEHYVQDSTFHTPXXXXXXXXXXXXFHTPNVKPNRLTGNTMNSIAKSDISINQKRVRSESNNGYTKEEPLFKKSKLEIDIKICKHIILNLVSKKYGDLNRYFLEPVDVEGLKLHDYFDIVKKPMDLGTVKNKLFDGFYQSNDEFAEDIKLIFKNCYLYNPEGHEVNRCGKLLEDIFNKLY 901
             I  + R  ++  F  PV+P  L IP Y + IK PMD  TI+ KL+   Y+   +   DF  +  N   FN P +    MA  ++  F++ M ++P  +     +      + +       +  T N +P R    T++     DI              Y  E    K  +L+  +K C+ ++  L++KK+   N  FLEPVD   + L  YFD VK+PMDLGT+  KL D  YQ+ ++F  D++L+FKNCY +NP+G  VN  G  LE++FN  +
Sbjct:  160 AIKAVKRLKDARPFLQPVDPVKLDIPFYFNYIKRPMDLSTIERKLNVGAYEVPEQITEDFNLMVNNSIKFNGPNAGISQMARNIQASFEKHMLNMPAKDAPPVIAKGRRSSAQEDAPIVIRRAQTHNGRPKR----TIHPPKSKDI--------------YPYESKKPKSKRLQQAMKFCQSVLKELMAKKHASYNYPFLEPVDPVSMNLPTYFDYVKEPMDLGTIAKKLNDWQYQTMEDFERDVRLVFKNCYTFNPDGTIVNMMGHRLEEVFNSKW 418          

HSP 2 Score: 73.559 bits (179), Expect = 6.020e-12
Identity = 37/96 (38.54%), Postives = 51/96 (53.12%), Query Frame = 2
Query:  110 FKVPVNPELLGIPNYPDIIKYPMDFGTIKIKLDKQVYQSANECKSDFLSVFRNCYIFNEPGSLYVDMALKLENLFKRKMTDLPVPEHYVQDSTFHT 397
            F  PV+P  + +P Y D +K PMD GTI  KL+   YQ+  + + D   VF+NCY FN  G++   M  +LE +F  K  D P  + Y  D    T
Sbjct:  340 FLEPVDPVSMNLPTYFDYVKEPMDLGTIAKKLNDWQYQTMEDFERDVRLVFKNCYTFNPDGTIVNMMGHRLEEVFNSKWADRPNLDDYDSDEDSRT 435          

HSP 3 Score: 53.5286 bits (127), Expect = 9.521e-6
Identity = 30/95 (31.58%), Postives = 51/95 (53.68%), Query Frame = 2
Query:  611 KHIILNLVSKKYGDLNRYFLEPVDVEGLKLHDYFDIVKKPMDLGTVKNKLFDGFYQSNDEFAEDIKLIFKNCYLYNPEGHEVNRCGKLLEDIFNK 895
            KH +L + + K     R FL+PVD   L +  YF+ +K+PMDL T++ KL  G Y+  ++  ED  L+  N   +N     +++  + ++  F K
Sbjct:  155 KHALLAIKAVKRLKDARPFLQPVDPVKLDIPFYFNYIKRPMDLSTIERKLNVGAYEVPEQITEDFNLMVNNSIKFNGPNAGISQMARNIQASFEK 249          
BLAST of Bromodomain-containing protein 2 vs. UniProt/SwissProt
Match: sp|Q9Y7N0|BDF1_SCHPO (SWR1 complex bromodomain subunit bdf1 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) OX=284812 GN=bdf1 PE=1 SV=1)

HSP 1 Score: 135.576 bits (340), Expect = 8.553e-32
Identity = 81/279 (29.03%), Postives = 131/279 (46.95%), Query Frame = 2
Query:   71 VINVLLRNSNSESFKVPVNPELLGIPNYPDIIKYPMDFGTIKIKLDKQVYQSANECKSDFLSVFRNCYIFNEPGSLYVDMALKLENLFKRKMTDLPVPEHYVQDSTFHTPXXXXXXXXXXXXFHTPNVKPNRLTGNTMNSIAKSDISINQKRVRSESNNGYTKEEPLFKKSKLEIDIKICKHIILNLVSKKYGDLNRYFLEPVDVEGLKLHDYFDIVKKPMDLGTVKNKLFDGFYQSNDEFAEDIKLIFKNCYLYNPEGHEVNRCGKLLEDIFNKLYQG 907
            ++  L R  NS  FKVPV+P    IP+YP I+K PMD GTI+ KL    Y    E   D   +F NC+++N   S    M   L+ +F+R++  LP  E         + + +        + ++     +     +    A S   + + + R   NN                 ++ C  ++  L  ++Y      F +PVD       DYFD++K+PMDL T+++KL    Y + +EF  DI L+F NC+ YNP G  V+  G+ LE++F + ++ 
Sbjct:   96 IVRQLKRTKNSAPFKVPVDPIKQNIPDYPTIVKNPMDLGTIEKKLTSYEYSVPQEFIDDMNLMFSNCFLYNGTESPVGSMGKALQEVFERQLKQLPDAEQPAAAPVKKSKQKSASTAPPRTRRNSSVSSTSASVAASTAPKAASPAVLPEGKPRRRKNNS---------------QMRFCSTVLKELYKRQYESFAFPFYQPVDPVACDCPDYFDVIKEPMDLSTIQSKLNKNEYSTLEEFESDILLMFNNCFTYNPPGTPVHVMGRQLENVFKEKWEA 359          
BLAST of Bromodomain-containing protein 2 vs. UniProt/SwissProt
Match: sp|Q9HGP4|YK82_SCHPO (Bromodomain-containing protein C631.02 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) OX=284812 GN=SPAC631.02 PE=1 SV=3)

HSP 1 Score: 134.806 bits (338), Expect = 4.985e-31
Identity = 87/281 (30.96%), Postives = 134/281 (47.69%), Query Frame = 2
Query:   71 VINVLLRNSNSESFKVPVNPELLGIPNYPDIIKYPMDFGTIKIKLDKQVYQSANECKSDFLSVFRNCYIFNEPGSLYVDMALKLENLFKRKMTDLPVPEHYVQDSTFHTPXXXXXXXXXXXXFHTPNVKPNRLTGNTMNSIAKSDISINQKRVRSESNNGYTKEEPLF----KKSKLEIDIKICKHIILNLVSKKYGDLNRYFLEPVDVEGLKLHDYFDIVKKPMDLGTVKNKLFDGFYQSNDEFAEDIKLIFKNCYLYNPEGHEVNRCGKLLEDIFNKLY 901
            ++  L R  +S  F+ PV+P    IP+YP IIK P+D GT++ K    VY SA     D   +F NC+++N   S    M   L+  F+R++  LP    YV                    +  P  +P  +T     +  +      Q  + S S++G    E ++     + K   ++K C+ ++  L+ K++      F +PV+       DYF ++K PMDLGT++NKL    Y S   F  D+ L+FKNCY +N  G  V+  GK LE IF KL+
Sbjct:  241 MLRQLRRGRDSIPFRAPVDPVKQNIPDYPTIIKNPIDLGTMQKKFSSGVYSSAQHFIDDMNLMFSNCFLYNGTESPVGVMGKNLQATFERQLKQLP--SAYV------------------TSYSRPGRRPRSMTAPKGGARTR-----RQAAMYSNSSSGI--RETMYDLKPHRRKDAAEMKFCQSVLKELLKKQHEAYAYPFYKPVNPTACGCPDYFKVIKHPMDLGTMQNKLNHNEYASMKAFEADMVLMFKNCYKFNSAGTPVHLMGKKLESIFQKLW 494          

HSP 2 Score: 71.2478 bits (173), Expect = 3.701e-11
Identity = 33/83 (39.76%), Postives = 50/83 (60.24%), Query Frame = 2
Query:  110 FKVPVNPELLGIPNYPDIIKYPMDFGTIKIKLDKQVYQSANECKSDFLSVFRNCYIFNEPGSLYVDMALKLENLFKRKMTDLP 358
            F  PVNP   G P+Y  +IK+PMD GT++ KL+   Y S    ++D + +F+NCY FN  G+    M  KLE++F++   + P
Sbjct:  416 FYKPVNPTACGCPDYFKVIKHPMDLGTMQNKLNHNEYASMKAFEADMVLMFKNCYKFNSAGTPVHLMGKKLESIFQKLWANKP 498          
BLAST of Bromodomain-containing protein 2 vs. TrEMBL
Match: A0A3S5BEG1 (Uncharacterized protein (Fragment) OS=Protopolystoma xenopodis OX=117903 GN=PXEA_LOCUS14669 PE=4 SV=1)

HSP 1 Score: 200.29 bits (508), Expect = 4.511e-53
Identity = 115/318 (36.16%), Postives = 173/318 (54.40%), Query Frame = 2
Query:   41 TNQLLYIKKNVINVLLRNSNSESFKVPVNPELLGIPNYPDIIKYPMDFGTIKIKLDKQVYQSANECKSDFLSVFRNCYIFNEPGSLYVDMALKLENLFKRKMTDLPVPEHYVQDSTFHTPXXXXXXXXXXXXFHTPNVKPNRLTGNTMNSIAKS----------DISINQKRVRSESNNGYTK---------------------EEPLFKKSKLEIDIKICKHIILNLVSKKYGDLNRYFLEPVDVEGLKLHDYFDIVKKPMDLGTVKNKLFDGFYQSNDEFAEDIKLIFKNCYLYNPEGHEVNRCGKLLEDIFNKLY 901
            TNQL +IKK+V+  LL+   S  F  PV+ + L +P+YP IIKYPMD GT+K +L+ + Y S++EC  D  ++FRNCY+FN+PG   V MA+KLE + + ++  +P PE  +         S               V+ N +  + +N + +S            SI +K V+ +  +   +                     E  + K+ +L   +K C +++ +L S++Y DLN  FL+PVD   L L+DY DI+K PMDLGT+K KL +G Y S  EFAED++L+F NCY YN E  +V + GK L+  F + Y
Sbjct:   36 TNQLEFIKKSVVGALLKEKISWPFSKPVDHQKLNLPDYPKIIKYPMDLGTLKQRLNLKFYHSSSECLDDLWTMFRNCYVFNKPGDDIVAMAIKLEQIARERLKHMPTPEIEINGQKSRPVSSAPTNVSTDSNMSV--VQSNHIEDSIVNEVPQSIPQNPPVQAPPTSIAKKPVKRKHESVLDELPATPHSSDESKPLQLFDNFAERSVGKRLRLTESLKACSNLLKDLSSQRYRDLNHLFLKPVDAAALGLYDYHDIIKCPMDLGTMKLKLENGQYHSKHEFAEDMRLMFLNCYKYNGEESDVAKIGKALQATFEEHY 351          
BLAST of Bromodomain-containing protein 2 vs. TrEMBL
Match: A0A0R3X129 (Uncharacterized protein OS=Hydatigena taeniaeformis OX=6205 GN=TTAC_LOCUS6859 PE=4 SV=2)

HSP 1 Score: 211.075 bits (536), Expect = 1.473e-52
Identity = 118/319 (36.99%), Postives = 174/319 (54.55%), Query Frame = 2
Query:   41 TNQLLYIKKNVINVLLRNSNSESFKVPVNPELLGIPNYPDIIKYPMDFGTIKIKLDKQVYQSANECKSDFLSVFRNCYIFNEPGSLYVDMALKLENLFKRKMTDLPVPE-----------------HYVQDSTFH-------------------TPXXXXXXXXXXXXFHTPNVKPNRLTGNTMNSIAKSDISINQKRVRSESNNGYTKEEPLFKKSKLEIDIKICKHIILNLVSKKYGDLNRYFLEPVDVEGLKLHDYFDIVKKPMDLGTVKNKLFDGFYQSNDEFAEDIKLIFKNCYLYNPEGHEVNRCGKLLEDIF 889
            TNQL YIK+NVI V+ ++  +  F  PV+   L +P+YP IIK+PMD GTIK +L+ + Y+   EC  D  ++FRNCYIFN+PG   V MA+KLE + + K+ +LP PE                 +   DS F                    TP    + + +     T N K  +   ++++ I  +  SI++ R R  S     +E  + K+ +L   +K C  ++ +L S +Y   N+ FL+PVDVE L LHDY DI+  PMDL T++ KL  G YQ+ +EFA D++L+F NCY YN E  +V+  G+ L+ IF
Sbjct:   15 TNQLEYIKRNVIAVIAKDKLAWPFLKPVDHHKLNLPDYPKIIKHPMDLGTIKQRLNLKFYRHGAECLRDLFTMFRNCYIFNKPGDDVVAMAMKLERVAREKLQNLPYPEVELTSQKLSAGHAPPTSNLSTDSNFSMSVLNNTEELNGSSLVPPTTPSGASMHQHQGPLSSTVNKKAPKRKPDSLDDIPSTPQSIDESRERRVSKKPKMEERVIGKRVRLSESLKQCSSLLKDLCSARYRQYNQLFLKPVDVERLGLHDYHDIITHPMDLSTIRTKLDSGAYQNKNEFAADMRLMFDNCYKYNGEKSDVSDLGRALQGIF 333          

HSP 2 Score: 68.1662 bits (165), Expect = 9.018e-8
Identity = 36/97 (37.11%), Postives = 54/97 (55.67%), Query Frame = 2
Query:   47 QLLYIKKNVINVLLRNSNSESFKVPVNPELLGIPNYPDIIKYPMDFGTIKIKLDKQVYQSANECKSDFLSVFRNCYIFNEPGSLYVDMALKLENLFK 337
            Q   + K++ +   R  N + F  PV+ E LG+ +Y DII +PMD  TI+ KLD   YQ+ NE  +D   +F NCY +N   S   D+   L+ +F+
Sbjct:  239 QCSSLLKDLCSARYRQYN-QLFLKPVDVERLGLHDYHDIITHPMDLSTIRTKLDSGAYQNKNEFAADMRLMFDNCYKYNGEKSDVSDLGRALQGIFE 334          

HSP 3 Score: 66.2402 bits (160), Expect = 4.579e-7
Identity = 33/80 (41.25%), Postives = 46/80 (57.50%), Query Frame = 2
Query:  665 FLEPVDVEGLKLHDYFDIVKKPMDLGTVKNKLFDGFYQSNDEFAEDIKLIFKNCYLYNPEGHEVNRCGKLLEDIFNKLYQ 904
            FL+PVD   L L DY  I+K PMDLGT+K +L   FY+   E   D+  +F+NCY++N  G +V      LE +  +  Q
Sbjct:   38 FLKPVDHHKLNLPDYPKIIKHPMDLGTIKQRLNLKFYRHGAECLRDLFTMFRNCYIFNKPGDDVVAMAMKLERVAREKLQ 117          
BLAST of Bromodomain-containing protein 2 vs. TrEMBL
Match: A0A0X3NGE9 (Bromodomain-containing protein 2 OS=Schistocephalus solidus OX=70667 GN=BRD2 PE=4 SV=1)

HSP 1 Score: 206.838 bits (525), Expect = 2.260e-52
Identity = 127/365 (34.79%), Postives = 189/365 (51.78%), Query Frame = 2
Query:   41 TNQLLYIKKNVINVLLRNSNSESFKVPVNPELLGIPNYPDIIKYPMDFGTIKIKLDKQVYQSANECKSDFLSVFRNCYIFNEPGSLYVDMALKLENLFKRKMTDLPV---------PEHYVQDSTFH------------------------------TPXXXXXXXXXXXXFHTPNVKP--NRLTGNTMNSIAKSDISINQKRVRSESNNGYTKEEPLFKKSKLEIDIKICKHIILNLVSKKYGDLNRYFLEPVDVEGLKLHDYFDIVKKPMDLGTVKNKLFDGFYQSNDEFAEDIKLIFKNCYLYNPEGHEVNRCGKLLEDIFNKLYQGAFGNSKITSKPTRTQH----RSYDDLQPLLQKILK 1000
            TNQL YIKK+V+  L ++     F  PV+ + L +P+YP IIK+PMD GTIK +L+ + Y+ A+EC  D  ++FRNCYIFN+PG   V MA+KLE L + ++T +P          P H    S+                                TP    +   +     T N KP   +   + ++    +  S++  R R +S     +E  + K+ +L   +K C  ++  + S ++  LN+ FL+PVDVEGL LHDY DI+  PMDL TV++KL  G Y + +EFA DI+L+F NCY YN E  EV   G++L+ IF + +      +KI+       H    R+ + LQ LLQ  +K
Sbjct:   16 TNQLEYIKKHVVTALQKDQLVWPFLKPVDHQKLNLPDYPKIIKHPMDLGTIKQRLNLKFYKCASECLDDIFTMFRNCYIFNKPGDDVVAMAVKLERLTRDRLTGMPFPEVEISQQKPNHSQTASSLMSNRSSDSNISMTVNNIQEEMNNGSIIVAPTTPSGVALVPHQGPLTSTVNKKPLKRKPEQSVVDESPSTPHSVDGSRDRRQSKKVKVEERVIGKRPRLSEPLKQCSTLLKEISSARHRHLNQLFLKPVDVEGLALHDYHDIITHPMDLSTVRSKLDSGAYLNKNEFAADIRLMFANCYKYNGEDSEVANVGRMLQGIFEEQF------AKISEDDVELNHAVDCRTPEGLQQLLQTAVK 374          
BLAST of Bromodomain-containing protein 2 vs. TrEMBL
Match: A0A183APR3 (Uncharacterized protein OS=Echinostoma caproni OX=27848 GN=ECPE_LOCUS8948 PE=4 SV=1)

HSP 1 Score: 207.608 bits (527), Expect = 1.055e-51
Identity = 122/328 (37.20%), Postives = 181/328 (55.18%), Query Frame = 2
Query:   41 TNQLLYIKKNVINVLLRNSNSESFKVPVNPELLGIPNYPDIIKYPMDFGTIKIKLDKQVYQSANECKSDFLSVFRNCYIFNEPGSLYVDMALKLENLFKRKMTDLPVPE---------------------HYVQDSTFHTPXXXXXXXXXXXXF----HTPNVKPN-----------RLTGNTMNSIAKS-----DISINQKRVRSESNNGYTKEEPLFKKSKLEIDIKICKHIILNLVSKKYGDLNRYFLEPVDVEGLKLHDYFDIVKKPMDLGTVKNKLFDGFYQSNDEFAEDIKLIFKNCYLYNPEGHEVNRCGKLLEDIFNKLY 901
            TNQL YIKK V+  L +      F  PV+ E L +P+YP IIK+PMD GTIK +L+ + Y S++EC  D  ++FRNCYIFN+PG   V MA+KLE + + ++  +P PE                     H + DS+     S  V            +TP V+P+           +    T++ I ++     D S ++++++        +E  + K+ +L   +K C +I+ ++ S++Y DLN  FL+PVD E + LHDY D+VKK MDL TVK KL  G Y++  EFA+DI+L+F NCY YN E  EV + GKLL+ IF + +
Sbjct:   29 TNQLEYIKKEVVGRLYKEKMVWPFTRPVDHERLNLPDYPRIIKHPMDLGTIKQRLNLKFYHSSSECLDDLFTMFRNCYIFNKPGDDVVAMAMKLEQIARERLKFMPTPETEIGPQKSTKAAKPVNSVLQPHSMDDSSGPPAPSNHVDGLNGSSLPSEPNTPVVRPSVTSSSGKKASKKKLDTTLDDIPQTPHSFDDPSRDRRQIKKPKRE--YEERNVGKRLRLSEALKGCSNILKDISSQRYRDLNHLFLKPVDAEAMGLHDYHDVVKKAMDLSTVKAKLESGQYKTKYEFADDIRLMFNNCYKYNGEDSEVAKVGKLLQAIFEEAF 354          
BLAST of Bromodomain-containing protein 2 vs. TrEMBL
Match: A0A2H1CEU6 (Bromodomain protein OS=Fasciola hepatica OX=6192 GN=D915_06781 PE=4 SV=1)

HSP 1 Score: 208.764 bits (530), Expect = 1.085e-51
Identity = 121/328 (36.89%), Postives = 180/328 (54.88%), Query Frame = 2
Query:   41 TNQLLYIKKNVINVLLRNSNSESFKVPVNPELLGIPNYPDIIKYPMDFGTIKIKLDKQVYQSANECKSDFLSVFRNCYIFNEPGSLYVDMALKLENLFKRKMTDLPVPE---------------------HYVQDSTFHTPXXXXXXXXXXXXF----HTPNVKPN-----------RLTGNTMNSIAKS-----DISINQKRVRSESNNGYTKEEPLFKKSKLEIDIKICKHIILNLVSKKYGDLNRYFLEPVDVEGLKLHDYFDIVKKPMDLGTVKNKLFDGFYQSNDEFAEDIKLIFKNCYLYNPEGHEVNRCGKLLEDIFNKLY 901
            TNQL YIKK V+  L +      F  PV+ E L +P+YP IIK+PMD GTIK +L+ + Y S++EC  D  ++FRNCYIFN+PG   V MA+KLE + + ++  +P PE                     H + DS+     S  V             TP V+P+           +    TM+ + ++     D S ++++++        +E  + K+ +L   +K C +I+ ++ S++Y DLN  FL+PVD E + LHDY D+VKK MDL TVK KL  G Y++  +FA+DI+L+F NCY YN E  EV + GKLL+ IF + +
Sbjct:   29 TNQLEYIKKEVVGRLYKEKMVWPFTRPVDHERLNLPDYPRIIKHPMDLGTIKQRLNLKFYHSSSECLDDLFTMFRNCYIFNKPGDDVVAMAMKLEQIARERLKFMPTPETEIGPQKSSKSTKPINSILQPHTMDDSSGLAASSNHVDGLNGSSLPSEPSTPVVRPSVTSSSGKKASKKKLDTTMDDVPQTPHSVDDASRDRRQIKKPKRE--FEERNVGKRLRLSEALKGCSNILKDISSQRYRDLNHLFLKPVDAEAMGLHDYHDVVKKAMDLSTVKAKLESGQYKTKYDFADDIRLMFNNCYKYNGEESEVAKVGKLLQAIFEESF 354          
BLAST of Bromodomain-containing protein 2 vs. Ensembl Cavefish
Match: ENSAMXT00000057848.1 (pep primary_assembly:Astyanax_mexicanus-2.0:12:831065:839047:1 gene:ENSAMXG00000012049.2 transcript:ENSAMXT00000057848.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 102.064 bits (253), Expect = 6.720e-23
Identity = 51/113 (45.13%), Postives = 74/113 (65.49%), Query Frame = 2
Query:   41 TNQLLYIKKNVINVLLRNSNSESFKVPVNPELLGIPNYPDIIKYPMDFGTIKIKLDKQVYQSANECKSDFLSVFRNCYIFNEPGSLYVDMALKLENLFKRKMTDLPVPEHYVQ 379
            TNQL Y+ K V+  L ++  S  F+ PV+   L +P+Y  IIK PMD GTIK +L+ + Y++A EC  DF ++F NCYI+N+PG   V MA  LE +F +K++++P  E  VQ
Sbjct:   48 TNQLQYLLKVVLKTLWKHQFSWPFQAPVDAVKLRLPDYYKIIKCPMDMGTIKKRLENRYYRNAQECIQDFNTMFTNCYIYNKPGDDIVLMAEALEKMFLQKISEMPQEEAEVQ 160          

HSP 2 Score: 71.2478 bits (173), Expect = 1.028e-12
Identity = 30/75 (40.00%), Postives = 47/75 (62.67%), Query Frame = 2
Query:  665 FLEPVDVEGLKLHDYFDIVKKPMDLGTVKNKLFDGFYQSNDEFAEDIKLIFKNCYLYNPEGHEVNRCGKLLEDIF 889
            F  PVD   L+L DY+ I+K PMD+GT+K +L + +Y++  E  +D   +F NCY+YN  G ++    + LE +F
Sbjct:   71 FQAPVDAVKLRLPDYYKIIKCPMDMGTIKKRLENRYYRNAQECIQDFNTMFTNCYIYNKPGDDIVLMAEALEKMF 145          
BLAST of Bromodomain-containing protein 2 vs. Ensembl Cavefish
Match: BRD3 (bromodomain-containing protein 3-like [Source:NCBI gene;Acc:103046549])

HSP 1 Score: 105.531 bits (262), Expect = 9.120e-23
Identity = 48/105 (45.71%), Postives = 65/105 (61.90%), Query Frame = 2
Query:  575 KKSKLEIDIKICKHIILNLVSKKYGDLNRYFLEPVDVEGLKLHDYFDIVKKPMDLGTVKNKLFDGFYQSNDEFAEDIKLIFKNCYLYNPEGHEVNRCGKLLEDIF 889
            KK KL   +K C  I+  ++SKK+      F +PVD E L+LHDY +I+K+PMDL TVK K+    Y     FA D++L+F NCY YNP  HEV    + L+D+F
Sbjct:  288 KKGKLSDHLKHCDTILKEMLSKKHAAYAWPFYKPVDAEALELHDYHEIIKQPMDLSTVKKKMDGREYPDAQSFAADVRLMFSNCYKYNPPDHEVVAMARKLQDVF 392          

HSP 2 Score: 95.5153 bits (236), Expect = 1.144e-19
Identity = 45/106 (42.45%), Postives = 65/106 (61.32%), Query Frame = 2
Query:   41 TNQLLYIKKNVINVLLRNSNSESFKVPVNPELLGIPNYPDIIKYPMDFGTIKIKLDKQVYQSANECKSDFLSVFRNCYIFNEPGSLYVDMALKLENLFKRKMTDLP 358
            TNQL Y++  V+  L R+  +  F  PV+   L +P+Y  +IK PMD GTIK +L+   Y +A EC  DF ++F NCYI+N+P    V MA  LE +F +K+  +P
Sbjct:   32 TNQLQYMQNVVVKTLWRHQFAWPFYTPVDAIKLSLPDYHKVIKNPMDMGTIKKRLENNYYWTAGECMQDFNTMFTNCYIYNKPTDDIVLMAQALEKIFLQKVAQMP 137          

HSP 3 Score: 68.1662 bits (165), Expect = 3.392e-11
Identity = 29/75 (38.67%), Postives = 43/75 (57.33%), Query Frame = 2
Query:  665 FLEPVDVEGLKLHDYFDIVKKPMDLGTVKNKLFDGFYQSNDEFAEDIKLIFKNCYLYNPEGHEVNRCGKLLEDIF 889
            F  PVD   L L DY  ++K PMD+GT+K +L + +Y +  E  +D   +F NCY+YN    ++    + LE IF
Sbjct:   55 FYTPVDAIKLSLPDYHKVIKNPMDMGTIKKRLENNYYWTAGECMQDFNTMFTNCYIYNKPTDDIVLMAQALEKIF 129          

HSP 4 Score: 67.0106 bits (162), Expect = 8.478e-11
Identity = 32/83 (38.55%), Postives = 48/83 (57.83%), Query Frame = 2
Query:  110 FKVPVNPELLGIPNYPDIIKYPMDFGTIKIKLDKQVYQSANECKSDFLSVFRNCYIFNEPGSLYVDMALKLENLFKRKMTDLP 358
            F  PV+ E L + +Y +IIK PMD  T+K K+D + Y  A    +D   +F NCY +N P    V MA KL+++F+ +   +P
Sbjct:  318 FYKPVDAEALELHDYHEIIKQPMDLSTVKKKMDGREYPDAQSFAADVRLMFSNCYKYNPPDHEVVAMARKLQDVFEMRFAKMP 400          
BLAST of Bromodomain-containing protein 2 vs. Ensembl Cavefish
Match: BRD3 (bromodomain-containing protein 3-like [Source:NCBI gene;Acc:103046549])

HSP 1 Score: 105.531 bits (262), Expect = 9.162e-23
Identity = 48/105 (45.71%), Postives = 65/105 (61.90%), Query Frame = 2
Query:  575 KKSKLEIDIKICKHIILNLVSKKYGDLNRYFLEPVDVEGLKLHDYFDIVKKPMDLGTVKNKLFDGFYQSNDEFAEDIKLIFKNCYLYNPEGHEVNRCGKLLEDIF 889
            KK KL   +K C  I+  ++SKK+      F +PVD E L+LHDY +I+K+PMDL TVK K+    Y     FA D++L+F NCY YNP  HEV    + L+D+F
Sbjct:  288 KKGKLSDHLKHCDTILKEMLSKKHAAYAWPFYKPVDAEALELHDYHEIIKQPMDLSTVKKKMDGREYPDAQSFAADVRLMFSNCYKYNPPDHEVVAMARKLQDVF 392          

HSP 2 Score: 95.5153 bits (236), Expect = 1.197e-19
Identity = 45/106 (42.45%), Postives = 65/106 (61.32%), Query Frame = 2
Query:   41 TNQLLYIKKNVINVLLRNSNSESFKVPVNPELLGIPNYPDIIKYPMDFGTIKIKLDKQVYQSANECKSDFLSVFRNCYIFNEPGSLYVDMALKLENLFKRKMTDLP 358
            TNQL Y++  V+  L R+  +  F  PV+   L +P+Y  +IK PMD GTIK +L+   Y +A EC  DF ++F NCYI+N+P    V MA  LE +F +K+  +P
Sbjct:   32 TNQLQYMQNVVVKTLWRHQFAWPFYTPVDAIKLSLPDYHKVIKNPMDMGTIKKRLENNYYWTAGECMQDFNTMFTNCYIYNKPTDDIVLMAQALEKIFLQKVAQMP 137          

HSP 3 Score: 68.1662 bits (165), Expect = 3.512e-11
Identity = 29/75 (38.67%), Postives = 43/75 (57.33%), Query Frame = 2
Query:  665 FLEPVDVEGLKLHDYFDIVKKPMDLGTVKNKLFDGFYQSNDEFAEDIKLIFKNCYLYNPEGHEVNRCGKLLEDIF 889
            F  PVD   L L DY  ++K PMD+GT+K +L + +Y +  E  +D   +F NCY+YN    ++    + LE IF
Sbjct:   55 FYTPVDAIKLSLPDYHKVIKNPMDMGTIKKRLENNYYWTAGECMQDFNTMFTNCYIYNKPTDDIVLMAQALEKIF 129          

HSP 4 Score: 67.0106 bits (162), Expect = 8.053e-11
Identity = 32/83 (38.55%), Postives = 48/83 (57.83%), Query Frame = 2
Query:  110 FKVPVNPELLGIPNYPDIIKYPMDFGTIKIKLDKQVYQSANECKSDFLSVFRNCYIFNEPGSLYVDMALKLENLFKRKMTDLP 358
            F  PV+ E L + +Y +IIK PMD  T+K K+D + Y  A    +D   +F NCY +N P    V MA KL+++F+ +   +P
Sbjct:  318 FYKPVDAEALELHDYHEIIKQPMDLSTVKKKMDGREYPDAQSFAADVRLMFSNCYKYNPPDHEVVAMARKLQDVFEMRFAKMP 400          
BLAST of Bromodomain-containing protein 2 vs. Ensembl Cavefish
Match: brd3a (bromodomain-containing protein 3 [Source:NCBI gene;Acc:103032475])

HSP 1 Score: 105.145 bits (261), Expect = 1.031e-22
Identity = 48/105 (45.71%), Postives = 65/105 (61.90%), Query Frame = 2
Query:  575 KKSKLEIDIKICKHIILNLVSKKYGDLNRYFLEPVDVEGLKLHDYFDIVKKPMDLGTVKNKLFDGFYQSNDEFAEDIKLIFKNCYLYNPEGHEVNRCGKLLEDIF 889
            K+ +L   +K C  I+  ++SKK+      F +PVD E L+LHDY DI+K PMDL TVK K+    YQ    FA D++L+F NCY YNP  HEV    + L+D+F
Sbjct:  285 KRGRLNEHLKHCDVILKEMLSKKHAAYAWPFYKPVDAEALELHDYHDIIKHPMDLSTVKKKMDSREYQDAQNFAADVRLMFSNCYKYNPPDHEVVAMARKLQDVF 389          

HSP 2 Score: 97.4413 bits (241), Expect = 2.589e-20
Identity = 48/106 (45.28%), Postives = 67/106 (63.21%), Query Frame = 2
Query:   41 TNQLLYIKKNVINVLLRNSNSESFKVPVNPELLGIPNYPDIIKYPMDFGTIKIKLDKQVYQSANECKSDFLSVFRNCYIFNEPGSLYVDMALKLENLFKRKMTDLP 358
            TNQL Y++  V+  L R+  +  F  PV+   LG+P+Y  IIK PMD GTIK +L+   Y SA+EC  DF ++F NCYI+N+P    V MA  LE +F +K+  +P
Sbjct:   32 TNQLQYMQNVVVKTLWRHQFAWPFYQPVDAIKLGLPDYHKIIKSPMDMGTIKKRLENVFYWSASECMQDFNTMFTNCYIYNKPTDDIVLMAQALEKIFLQKVALMP 137          

HSP 3 Score: 72.0182 bits (175), Expect = 1.948e-12
Identity = 34/83 (40.96%), Postives = 50/83 (60.24%), Query Frame = 2
Query:  110 FKVPVNPELLGIPNYPDIIKYPMDFGTIKIKLDKQVYQSANECKSDFLSVFRNCYIFNEPGSLYVDMALKLENLFKRKMTDLP 358
            F  PV+ E L + +Y DIIK+PMD  T+K K+D + YQ A    +D   +F NCY +N P    V MA KL+++F+ +   +P
Sbjct:  315 FYKPVDAEALELHDYHDIIKHPMDLSTVKKKMDSREYQDAQNFAADVRLMFSNCYKYNPPDHEVVAMARKLQDVFEMRFAKMP 397          

HSP 4 Score: 70.4774 bits (171), Expect = 6.101e-12
Identity = 32/75 (42.67%), Postives = 44/75 (58.67%), Query Frame = 2
Query:  665 FLEPVDVEGLKLHDYFDIVKKPMDLGTVKNKLFDGFYQSNDEFAEDIKLIFKNCYLYNPEGHEVNRCGKLLEDIF 889
            F +PVD   L L DY  I+K PMD+GT+K +L + FY S  E  +D   +F NCY+YN    ++    + LE IF
Sbjct:   55 FYQPVDAIKLGLPDYHKIIKSPMDMGTIKKRLENVFYWSASECMQDFNTMFTNCYIYNKPTDDIVLMAQALEKIF 129          
BLAST of Bromodomain-containing protein 2 vs. Ensembl Cavefish
Match: brdt (bromodomain testis-specific protein [Source:NCBI gene;Acc:103040769])

HSP 1 Score: 105.916 bits (263), Expect = 1.121e-22
Identity = 49/107 (45.79%), Postives = 67/107 (62.62%), Query Frame = 2
Query:  569 LFKKSKLEIDIKICKHIILNLVSKKYGDLNRYFLEPVDVEGLKLHDYFDIVKKPMDLGTVKNKLFDGFYQSNDEFAEDIKLIFKNCYLYNPEGHEVNRCGKLLEDIF 889
            + +K KL   +K C  I+  L SKK+G     F +PVD E L LHDY DI+++PMDL T+K K+ +  Y    +FA DI+L+F NCY YNP  HEV    + L+D+F
Sbjct:  261 VGRKVKLSERLKHCSGILKELFSKKHGMYAWPFYKPVDAERLGLHDYHDIIREPMDLSTIKKKMDNREYTDASQFAADIRLMFSNCYKYNPPTHEVVAMARKLQDVF 367          

HSP 2 Score: 98.5969 bits (244), Expect = 1.708e-20
Identity = 52/120 (43.33%), Postives = 70/120 (58.33%), Query Frame = 2
Query:   41 TNQLLYIKKNVINVLLRNSNSESFKVPVNPELLGIPNYPDIIKYPMDFGTIKIKLDKQVYQSANECKSDFLSVFRNCYIFNEPGSLYVDMALKLENLFKRKMTDLPVPEHYVQDSTFHTP 400
            TNQL Y++K VI  L R+  S  F+ PV+   L +P+Y  IIK PMD  TIK +L+   Y  A EC  DF ++F NCY++N PG   V MA  LE LF  K++++P  E  +   T   P
Sbjct:   27 TNQLQYLEKVVIRALWRHHFSWPFRQPVDAVQLNLPDYYTIIKNPMDLNTIKKRLENNYYWKAMECIQDFNTMFTNCYVYNRPGDDIVLMAQALEKLFLEKVSEMPQDECEITAVTNKAP 146          

HSP 3 Score: 70.8626 bits (172), Expect = 6.444e-12
Identity = 34/83 (40.96%), Postives = 50/83 (60.24%), Query Frame = 2
Query:  110 FKVPVNPELLGIPNYPDIIKYPMDFGTIKIKLDKQVYQSANECKSDFLSVFRNCYIFNEPGSLYVDMALKLENLFKRKMTDLP 358
            F  PV+ E LG+ +Y DII+ PMD  TIK K+D + Y  A++  +D   +F NCY +N P    V MA KL+++F+     +P
Sbjct:  293 FYKPVDAERLGLHDYHDIIREPMDLSTIKKKMDNREYTDASQFAADIRLMFSNCYKYNPPTHEVVAMARKLQDVFESHFAKIP 375          

HSP 4 Score: 68.1662 bits (165), Expect = 3.870e-11
Identity = 30/75 (40.00%), Postives = 44/75 (58.67%), Query Frame = 2
Query:  665 FLEPVDVEGLKLHDYFDIVKKPMDLGTVKNKLFDGFYQSNDEFAEDIKLIFKNCYLYNPEGHEVNRCGKLLEDIF 889
            F +PVD   L L DY+ I+K PMDL T+K +L + +Y    E  +D   +F NCY+YN  G ++    + LE +F
Sbjct:   50 FRQPVDAVQLNLPDYYTIIKNPMDLNTIKKRLENNYYWKAMECIQDFNTMFTNCYVYNRPGDDIVLMAQALEKLF 124          
BLAST of Bromodomain-containing protein 2 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000008098.1 (pep scaffold:Pmarinus_7.0:GL481104:2991:16154:-1 gene:ENSPMAG00000007319.1 transcript:ENSPMAT00000008098.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 108.612 bits (270), Expect = 1.535e-24
Identity = 51/112 (45.54%), Postives = 74/112 (66.07%), Query Frame = 2
Query:   32 YPYTNQLLYIKKNVINVLLRNSNSESFKVPVNPELLGIPNYPDIIKYPMDFGTIKIKLDKQVYQSANECKSDFLSVFRNCYIFNEPGSLYVDMALKLENLFKRKMTDLPVPE 367
            Y  TNQL +++++V+ VL R+  +  F  PV+   L +P+Y  IIK PMD GTIK +L+   Y SA+EC SDF ++F NCY++N+PG     MA  LE  F +K+T++PV E
Sbjct:   33 YQLTNQLQFMQRSVLKVLWRHHFAWPFLQPVDAAALNLPDYHKIIKQPMDMGTIKQRLESSYYWSASECISDFKTMFNNCYVYNKPGDDIAIMAQALEKAFLQKITEMPVEE 144          

HSP 2 Score: 102.449 bits (254), Expect = 1.250e-22
Identity = 44/104 (42.31%), Postives = 62/104 (59.62%), Query Frame = 2
Query:  578 KSKLEIDIKICKHIILNLVSKKYGDLNRYFLEPVDVEGLKLHDYFDIVKKPMDLGTVKNKLFDGFYQSNDEFAEDIKLIFKNCYLYNPEGHEVNRCGKLLEDIF 889
            +S+    ++ C  ++  L+SK +      F  PVD   L LHDY DI+K PMDLGT++ KL    Y S  EFA D++L+F NCY YNP  H+V    + L+D+F
Sbjct:  315 RSRPSAQLRYCGSLLKELISKNHAAYAWPFYNPVDARALGLHDYHDIIKHPMDLGTIRRKLEAREYASGQEFASDVRLMFSNCYKYNPPEHDVVAMARKLQDVF 418          

HSP 3 Score: 79.337 bits (194), Expect = 2.034e-15
Identity = 37/99 (37.37%), Postives = 55/99 (55.56%), Query Frame = 2
Query:  665 FLEPVDVEGLKLHDYFDIVKKPMDLGTVKNKLFDGFYQSNDEFAEDIKLIFKNCYLYNPEGHEVNRCGKLLEDIF-NKLYQGAFGNSKITSKPTRTQHR 958
            FL+PVD   L L DY  I+K+PMD+GT+K +L   +Y S  E   D K +F NCY+YN  G ++    + LE  F  K+ +     + +T+   R + R
Sbjct:   59 FLQPVDAAALNLPDYHKIIKQPMDMGTIKQRLESSYYWSASECISDFKTMFNNCYVYNKPGDDIAIMAQALEKAFLQKITEMPVEETPVTTGAARGRGR 157          

HSP 4 Score: 73.1738 bits (178), Expect = 1.800e-13
Identity = 38/107 (35.51%), Postives = 61/107 (57.01%), Query Frame = 2
Query:   41 TNQLLYIKKNVINVLLRNSNSESFKV--PVNPELLGIPNYPDIIKYPMDFGTIKIKLDKQVYQSANECKSDFLSVFRNCYIFNEPGSLYVDMALKLENLFKRKMTDL 355
            + QL Y    +  ++ +N  + ++    PV+   LG+ +Y DIIK+PMD GTI+ KL+ + Y S  E  SD   +F NCY +N P    V MA KL+++F+ +   +
Sbjct:  319 SAQLRYCGSLLKELISKNHAAYAWPFYNPVDARALGLHDYHDIIKHPMDLGTIRRKLEAREYASGQEFASDVRLMFSNCYKYNPPEHDVVAMARKLQDVFEMRFARM 425          
BLAST of Bromodomain-containing protein 2 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000002732.1 (pep scaffold:Pmarinus_7.0:GL482934:3:7597:-1 gene:ENSPMAG00000002495.1 transcript:ENSPMAT00000002732.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 99.3673 bits (246), Expect = 2.843e-22
Identity = 47/105 (44.76%), Postives = 65/105 (61.90%), Query Frame = 2
Query:  575 KKSKLEIDIKICKHIILNLVSKKYGDLNRYFLEPVDVEGLKLHDYFDIVKKPMDLGTVKNKLFDGFYQSNDEFAEDIKLIFKNCYLYNPEGHEVNRCGKLLEDIF 889
            KK KL   +K C  I+  L +KK+      F +PVD   L LHDY DI+K PMDL T+KNK+ +  Y+   EFA D++++F NCY YNP  H+V    + L+D+F
Sbjct:  307 KKVKLSEQLKHCNGILKELFAKKHAAYAWPFYKPVDASTLGLHDYHDIIKHPMDLSTIKNKMDNRDYRDAQEFAADVRVMFSNCYKYNPPDHDVVSMARKLQDVF 411          

HSP 2 Score: 95.1301 bits (235), Expect = 6.643e-21
Identity = 46/109 (42.20%), Postives = 67/109 (61.47%), Query Frame = 2
Query:   41 TNQLLYIKKNVINVLLRNSNSESFKVPVNPELLGIPNYPDIIKYPMDFGTIKIKLDKQVYQSANECKSDFLSVFRNCYIFNEPGSLYVDMALKLENLFKRKMTDLPVPE 367
            TNQL Y+++ V+  L ++  +  F VPV+   L +P+Y  IIK PMD GTI+ +L+   Y S  EC  DF ++F NCY++N+P    V MA  LE LF +K+  +P  E
Sbjct:   32 TNQLQYLQRTVMKALWKHQFAWPFNVPVDANALHLPDYHKIIKQPMDMGTIRRRLENNYYWSGGECIQDFNTMFTNCYLYNKPTDDIVLMAQTLERLFLQKVALMPQEE 140          

HSP 3 Score: 68.5514 bits (166), Expect = 2.452e-12
Identity = 34/81 (41.98%), Postives = 50/81 (61.73%), Query Frame = 2
Query:  101 SESFKVPVNPELLGIPNYPDIIKYPMDFGTIKIKLDKQVYQSANECKSDFLSVFRNCYIFNEPGSLYVDMALKLENLFKRK 343
            +  F  PV+   LG+ +Y DIIK+PMD  TIK K+D + Y+ A E  +D   +F NCY +N P    V MA KL+++F+ +
Sbjct:  334 AWPFYKPVDASTLGLHDYHDIIKHPMDLSTIKNKMDNRDYRDAQEFAADVRVMFSNCYKYNPPDHDVVSMARKLQDVFEMR 414          

HSP 4 Score: 67.781 bits (164), Expect = 4.794e-12
Identity = 30/75 (40.00%), Postives = 44/75 (58.67%), Query Frame = 2
Query:  665 FLEPVDVEGLKLHDYFDIVKKPMDLGTVKNKLFDGFYQSNDEFAEDIKLIFKNCYLYNPEGHEVNRCGKLLEDIF 889
            F  PVD   L L DY  I+K+PMD+GT++ +L + +Y S  E  +D   +F NCYLYN    ++    + LE +F
Sbjct:   55 FNVPVDANALHLPDYHKIIKQPMDMGTIRRRLENNYYWSGGECIQDFNTMFTNCYLYNKPTDDIVLMAQTLERLF 129          
BLAST of Bromodomain-containing protein 2 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000002730.1 (pep scaffold:Pmarinus_7.0:GL482934:3:7765:-1 gene:ENSPMAG00000002495.1 transcript:ENSPMAT00000002730.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 98.9821 bits (245), Expect = 4.952e-22
Identity = 47/105 (44.76%), Postives = 65/105 (61.90%), Query Frame = 2
Query:  575 KKSKLEIDIKICKHIILNLVSKKYGDLNRYFLEPVDVEGLKLHDYFDIVKKPMDLGTVKNKLFDGFYQSNDEFAEDIKLIFKNCYLYNPEGHEVNRCGKLLEDIF 889
            KK KL   +K C  I+  L +KK+      F +PVD   L LHDY DI+K PMDL T+KNK+ +  Y+   EFA D++++F NCY YNP  H+V    + L+D+F
Sbjct:  325 KKVKLSEQLKHCNGILKELFAKKHAAYAWPFYKPVDASTLGLHDYHDIIKHPMDLSTIKNKMDNRDYRDAQEFAADVRVMFSNCYKYNPPDHDVVSMARKLQDVF 429          

HSP 2 Score: 95.5153 bits (236), Expect = 6.260e-21
Identity = 46/109 (42.20%), Postives = 67/109 (61.47%), Query Frame = 2
Query:   41 TNQLLYIKKNVINVLLRNSNSESFKVPVNPELLGIPNYPDIIKYPMDFGTIKIKLDKQVYQSANECKSDFLSVFRNCYIFNEPGSLYVDMALKLENLFKRKMTDLPVPE 367
            TNQL Y+++ V+  L ++  +  F VPV+   L +P+Y  IIK PMD GTI+ +L+   Y S  EC  DF ++F NCY++N+P    V MA  LE LF +K+  +P  E
Sbjct:   63 TNQLQYLQRTVMKALWKHQFAWPFNVPVDANALHLPDYHKIIKQPMDMGTIRRRLENNYYWSGGECIQDFNTMFTNCYLYNKPTDDIVLMAQTLERLFLQKVALMPQEE 171          

HSP 3 Score: 68.9366 bits (167), Expect = 1.968e-12
Identity = 34/78 (43.59%), Postives = 49/78 (62.82%), Query Frame = 2
Query:  110 FKVPVNPELLGIPNYPDIIKYPMDFGTIKIKLDKQVYQSANECKSDFLSVFRNCYIFNEPGSLYVDMALKLENLFKRK 343
            F  PV+   LG+ +Y DIIK+PMD  TIK K+D + Y+ A E  +D   +F NCY +N P    V MA KL+++F+ +
Sbjct:  355 FYKPVDASTLGLHDYHDIIKHPMDLSTIKNKMDNRDYRDAQEFAADVRVMFSNCYKYNPPDHDVVSMARKLQDVFEMR 432          

HSP 4 Score: 67.3958 bits (163), Expect = 7.413e-12
Identity = 30/75 (40.00%), Postives = 44/75 (58.67%), Query Frame = 2
Query:  665 FLEPVDVEGLKLHDYFDIVKKPMDLGTVKNKLFDGFYQSNDEFAEDIKLIFKNCYLYNPEGHEVNRCGKLLEDIF 889
            F  PVD   L L DY  I+K+PMD+GT++ +L + +Y S  E  +D   +F NCYLYN    ++    + LE +F
Sbjct:   86 FNVPVDANALHLPDYHKIIKQPMDMGTIRRRLENNYYWSGGECIQDFNTMFTNCYLYNKPTDDIVLMAQTLERLF 160          
BLAST of Bromodomain-containing protein 2 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000008812.1 (pep scaffold:Pmarinus_7.0:GL478772:7873:35829:1 gene:ENSPMAG00000007951.1 transcript:ENSPMAT00000008812.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 95.1301 bits (235), Expect = 3.207e-20
Identity = 48/109 (44.04%), Postives = 68/109 (62.39%), Query Frame = 2
Query:   41 TNQLLYIKKNVINVLLRNSNSESFKVPVNPELLGIPNYPDIIKYPMDFGTIKIKLDKQVYQSANECKSDFLSVFRNCYIFNEPGSLYVDMALKLENLFKRKMTDLPVPE 367
            TNQL Y++K V+  L ++  +  F  PV+   L +P+Y +IIK PMD GTIK +L+   Y +A EC  DF ++F NCYI+N P    V MA  LE  F +K+ ++PV E
Sbjct:   31 TNQLQYLQKVVMKALWKHQFAWPFHHPVDAAKLNLPDYYNIIKNPMDMGTIKKRLESNFYFTAVECIQDFSTMFTNCYIYNRPNDDIVLMAQTLEKFFLQKVAEMPVEE 139          

HSP 2 Score: 66.6254 bits (161), Expect = 1.999e-11
Identity = 30/75 (40.00%), Postives = 43/75 (57.33%), Query Frame = 2
Query:  665 FLEPVDVEGLKLHDYFDIVKKPMDLGTVKNKLFDGFYQSNDEFAEDIKLIFKNCYLYNPEGHEVNRCGKLLEDIF 889
            F  PVD   L L DY++I+K PMD+GT+K +L   FY +  E  +D   +F NCY+YN    ++    + LE  F
Sbjct:   54 FHHPVDAAKLNLPDYYNIIKNPMDMGTIKKRLESNFYFTAVECIQDFSTMFTNCYIYNRPNDDIVLMAQTLEKFF 128          

HSP 3 Score: 56.9954 bits (136), Expect = 1.651e-8
Identity = 26/54 (48.15%), Postives = 34/54 (62.96%), Query Frame = 2
Query:  599 IKICKHIILNLVSKKYGDLNRYFLEPVDVEGLKLHDYFDIVKKPMDLGTVKNKL 760
            +K C  II  +++KK+      F +PVD E L LHDY DI+K PMDL T+K  L
Sbjct:  301 LKHCSSIIKEMLAKKHAAYAWPFYKPVDAESLGLHDYHDIIKHPMDLSTIKTFL 354          
BLAST of Bromodomain-containing protein 2 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000006336.1 (pep scaffold:Pmarinus_7.0:GL479543:3524:30791:1 gene:ENSPMAG00000005717.1 transcript:ENSPMAT00000006336.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 73.9442 bits (180), Expect = 1.215e-13
Identity = 35/73 (47.95%), Postives = 47/73 (64.38%), Query Frame = 2
Query:  665 FLEPVDVEGLKLHDYFDIVKKPMDLGTVKNKLFDGFYQSNDEFAEDIKLIFKNCYLYNPEGHEVNR-CGKLLE 880
            F +PVD + L + DYFDIVK PMDL T+K KL  G YQ   ++ +D+ L+F N +LYN +   V + C KL E
Sbjct:  819 FRQPVDPQALGIPDYFDIVKTPMDLSTIKRKLDTGQYQEPWQYVDDVWLMFNNAWLYNRKTSRVYKYCSKLAE 891          

HSP 2 Score: 63.1586 bits (152), Expect = 2.936e-10
Identity = 31/79 (39.24%), Postives = 46/79 (58.23%), Query Frame = 2
Query:  110 FKVPVNPELLGIPNYPDIIKYPMDFGTIKIKLDKQVYQSANECKSDFLSVFRNCYIFNEPGSLYVDMALKLENLFKRKM 346
            F+ PV+P+ LGIP+Y DI+K PMD  TIK KLD   YQ   +   D   +F N +++N   S       KL  +F++++
Sbjct:  819 FRQPVDPQALGIPDYFDIVKTPMDLSTIKRKLDTGQYQEPWQYVDDVWLMFNNAWLYNRKTSRVYKYCSKLAEVFEQEI 897          
BLAST of Bromodomain-containing protein 2 vs. Ensembl Yeast
Match: BDF2 (Protein involved in transcription initiation; acts at TATA-containing promoters; associates with the basal transcription factor TFIID; contains two bromodomains; corresponds to the C-terminal region of mammalian TAF1; redundant with Bdf1p; protein abundance increases in response to DNA replication stress; BDF2 has a paralog, BDF1, that arose from the whole genome duplication [Source:SGD;Acc:S000002228])

HSP 1 Score: 144.05 bits (362), Expect = 3.936e-36
Identity = 93/279 (33.33%), Postives = 148/279 (53.05%), Query Frame = 2
Query:   89 RNSNSESFKVPVNPELLGIPNYPDIIKYPMDFGTIKIKLDKQVYQSANECKSDFLSVFRNCYIFNEPGSLYVDMALKLENLFKRKMTDLP---VPEHYVQDSTFHTPXXXXXXXXXXXXFHTPNVKPNRLTGNTMNSIAKSDISINQKRVRSESNNGYTKEEPLF--------KKSKLEIDIKICKHIILNLVSKKYGDLNRYFLEPVDVEGLKLHDYFDIVKKPMDLGTVKNKLFDGFYQSNDEFAEDIKLIFKNCYLYNPEGHEVNRCGKLLEDIFN 892
            R  ++  F  PV+P  L IP+Y + ++ PMD   I+ KL   VY S  +  SDF ++  NC  FN P S    MA +++  F++K++ +P   +P   ++ ++          + K+    +P V   R    T ++I +S         R +      K + LF        K   L+   + C  I+  L+SKK  D+N  FL+PVD   L L +YFD+VK PMDLGT+ N L +  Y++ D+F +D+ L+F NC+ +NPEG+EV+  GK L+++FN
Sbjct:  151 RLKDARPFLKPVDPIALNIPHYFNYVQTPMDLSLIETKLQGNVYHSVEQVTSDFKTMVDNCLNFNGPESSISSMAKRIQKYFEKKLSAMPPRVLPASALKKTS--------RNRKKNEDMDSPLV-IRRSVSTTNDNIGESGNREGVSGGRPKRTIHPPKSKDLFDIYENSKPKSKTLQKKFRTCLKILKVLMSKKNSDINFPFLQPVDPIALNLPNYFDVVKNPMDLGTISNNLMNWKYKTIDQFVDDLNLVFYNCFQFNPEGNEVHSMGKKLKELFN 420          

HSP 2 Score: 62.3882 bits (150), Expect = 2.391e-10
Identity = 35/91 (38.46%), Postives = 50/91 (54.95%), Query Frame = 2
Query:   71 VINVLLRNSNSE---SFKVPVNPELLGIPNYPDIIKYPMDFGTIKIKLDKQVYQSANECKSDFLSVFRNCYIFNEPGSLYVDMALKLENLF 334
            ++ VL+   NS+    F  PV+P  L +PNY D++K PMD GTI   L    Y++ ++   D   VF NC+ FN  G+    M  KL+ LF
Sbjct:  329 ILKVLMSKKNSDINFPFLQPVDPIALNLPNYFDVVKNPMDLGTISNNLMNWKYKTIDQFVDDLNLVFYNCFQFNPEGNEVHSMGKKLKELF 419          

HSP 3 Score: 50.8322 bits (120), Expect = 9.395e-7
Identity = 26/79 (32.91%), Postives = 40/79 (50.63%), Query Frame = 2
Query:  659 RYFLEPVDVEGLKLHDYFDIVKKPMDLGTVKNKLFDGFYQSNDEFAEDIKLIFKNCYLYNPEGHEVNRCGKLLEDIFNK 895
            R FL+PVD   L +  YF+ V+ PMDL  ++ KL    Y S ++   D K +  NC  +N     ++   K ++  F K
Sbjct:  156 RPFLKPVDPIALNIPHYFNYVQTPMDLSLIETKLQGNVYHSVEQVTSDFKTMVDNCLNFNGPESSISSMAKRIQKYFEK 234          
BLAST of Bromodomain-containing protein 2 vs. Ensembl Yeast
Match: BDF1 (Protein involved in transcription initiation; functions at TATA-containing promoters; associates with the basal transcription factor TFIID; contains two bromodomains; corresponds to the C-terminal region of mammalian TAF1; redundant with Bdf2p; BDF1 has a paralog, BDF2, that arose from the whole genome duplication [Source:SGD;Acc:S000004391])

HSP 1 Score: 141.354 bits (355), Expect = 4.377e-35
Identity = 89/277 (32.13%), Postives = 137/277 (49.46%), Query Frame = 2
Query:   71 VINVLLRNSNSESFKVPVNPELLGIPNYPDIIKYPMDFGTIKIKLDKQVYQSANECKSDFLSVFRNCYIFNEPGSLYVDMALKLENLFKRKMTDLPVPEHYVQDSTFHTPXXXXXXXXXXXXFHTPNVKPNRLTGNTMNSIAKSDISINQKRVRSESNNGYTKEEPLFKKSKLEIDIKICKHIILNLVSKKYGDLNRYFLEPVDVEGLKLHDYFDIVKKPMDLGTVKNKLFDGFYQSNDEFAEDIKLIFKNCYLYNPEGHEVNRCGKLLEDIFNKLY 901
             I  + R  ++  F  PV+P  L IP Y + IK PMD  TI+ KL+   Y+   +   DF  +  N   FN P +    MA  ++  F++ M ++P  +     +      + +       +  T N +P R    T++     DI              Y  E    K  +L+  +K C+ ++  L++KK+   N  FLEPVD   + L  YFD VK+PMDLGT+  KL D  YQ+ ++F  D++L+FKNCY +NP+G  VN  G  LE++FN  +
Sbjct:  160 AIKAVKRLKDARPFLQPVDPVKLDIPFYFNYIKRPMDLSTIERKLNVGAYEVPEQITEDFNLMVNNSIKFNGPNAGISQMARNIQASFEKHMLNMPAKDAPPVIAKGRRSSAQEDAPIVIRRAQTHNGRPKR----TIHPPKSKDI--------------YPYESKKPKSKRLQQAMKFCQSVLKELMAKKHASYNYPFLEPVDPVSMNLPTYFDYVKEPMDLGTIAKKLNDWQYQTMEDFERDVRLVFKNCYTFNPDGTIVNMMGHRLEEVFNSKW 418          

HSP 2 Score: 73.559 bits (179), Expect = 8.669e-14
Identity = 37/96 (38.54%), Postives = 51/96 (53.12%), Query Frame = 2
Query:  110 FKVPVNPELLGIPNYPDIIKYPMDFGTIKIKLDKQVYQSANECKSDFLSVFRNCYIFNEPGSLYVDMALKLENLFKRKMTDLPVPEHYVQDSTFHT 397
            F  PV+P  + +P Y D +K PMD GTI  KL+   YQ+  + + D   VF+NCY FN  G++   M  +LE +F  K  D P  + Y  D    T
Sbjct:  340 FLEPVDPVSMNLPTYFDYVKEPMDLGTIAKKLNDWQYQTMEDFERDVRLVFKNCYTFNPDGTIVNMMGHRLEEVFNSKWADRPNLDDYDSDEDSRT 435          

HSP 3 Score: 53.5286 bits (127), Expect = 1.371e-7
Identity = 30/95 (31.58%), Postives = 51/95 (53.68%), Query Frame = 2
Query:  611 KHIILNLVSKKYGDLNRYFLEPVDVEGLKLHDYFDIVKKPMDLGTVKNKLFDGFYQSNDEFAEDIKLIFKNCYLYNPEGHEVNRCGKLLEDIFNK 895
            KH +L + + K     R FL+PVD   L +  YF+ +K+PMDL T++ KL  G Y+  ++  ED  L+  N   +N     +++  + ++  F K
Sbjct:  155 KHALLAIKAVKRLKDARPFLQPVDPVKLDIPFYFNYIKRPMDLSTIERKLNVGAYEVPEQITEDFNLMVNNSIKFNGPNAGISQMARNIQASFEK 249          
BLAST of Bromodomain-containing protein 2 vs. Ensembl Yeast
Match: GCN5 (Catalytic subunit of ADA and SAGA histone acetyltransferase complexes; modifies N-terminal lysines on histones H2B and H3; acetylates Rsc4p, a subunit of the RSC chromatin-remodeling complex, altering replication stress tolerance; relocalizes to the cytosol in response to hypoxia; mutant displays reduced transcription elongation in the G-less-based run-on (GLRO) assay; greater involvement in repression of RNAPII-dependent transcription than in activation [Source:SGD;Acc:S000003484])

HSP 1 Score: 62.003 bits (149), Expect = 2.195e-10
Identity = 35/104 (33.65%), Postives = 55/104 (52.88%), Query Frame = 2
Query:   65 KNVINVLLRNSNSESFKVPVNPELLGIPNYPDIIKYPMDFGTIKIKLDKQVYQSANECKSDFLSVFRNCYIFNEPGSLYVDMALKLENLFKRKMTDLPVPEHYV 376
            +N++  L  ++ +  F  PVN E   +P+Y D IK PMD  T++IKL+   YQ   +   D   VF NC ++N   + Y   A +LE  F  K+ ++P   H +
Sbjct:  337 QNILTELQNHAAAWPFLQPVNKE--EVPDYYDFIKEPMDLSTMEIKLESNKYQKMEDFIYDARLVFNNCRMYNGENTSYYKYANRLEKFFNNKVKEIPEYSHLI 438          

HSP 2 Score: 60.077 bits (144), Expect = 9.084e-10
Identity = 31/76 (40.79%), Postives = 46/76 (60.53%), Query Frame = 2
Query:  665 FLEPVDVEGLKLHDYFDIVKKPMDLGTVKNKLFDGFYQSNDEFAEDIKLIFKNCYLYNPEGHEVNRCGKLLEDIFN 892
            FL+PV+ E  ++ DY+D +K+PMDL T++ KL    YQ  ++F  D +L+F NC +YN E     +    LE  FN
Sbjct:  352 FLQPVNKE--EVPDYYDFIKEPMDLSTMEIKLESNKYQKMEDFIYDARLVFNNCRMYNGENTSYYKYANRLEKFFN 425          
BLAST of Bromodomain-containing protein 2 vs. Ensembl Yeast
Match: SPT7 (Subunit of the SAGA transcriptional regulatory complex; involved in proper assembly of the complex; also present as a C-terminally truncated form in the SLIK/SALSA transcriptional regulatory complex [Source:SGD;Acc:S000000285])

HSP 1 Score: 50.447 bits (119), Expect = 1.358e-6
Identity = 35/97 (36.08%), Postives = 49/97 (50.52%), Query Frame = 2
Query:  608 CKHIILNLVSKKYGDLNRYFLEPVDVEGLKLHDYFDIVKKPMDLGTVKNKLFDGFYQSNDEFAEDIKLIFKNCYLYNPE------GHEVNRCGKLLE 880
            C+ ++L L  + Y + +  FL  V     +  +Y  I+KK MDL TV  KL    Y S  EF +DI LI+KNC  YN +      GH +    K L+
Sbjct:  449 CEKVVLEL--RNYTEHSTPFLNKVSKR--EAPNYHQIIKKSMDLNTVLKKLKSFQYDSKQEFVDDIMLIWKNCLTYNSDPSHFLRGHAIAMQKKSLQ 541          
BLAST of Bromodomain-containing protein 2 vs. Ensembl Nematostella
Match: EDO31845 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SWS2])

HSP 1 Score: 105.145 bits (261), Expect = 1.013e-23
Identity = 49/105 (46.67%), Postives = 67/105 (63.81%), Query Frame = 2
Query:  575 KKSKLEIDIKICKHIILNLVSKKYGDLNRYFLEPVDVEGLKLHDYFDIVKKPMDLGTVKNKLFDGFYQSNDEFAEDIKLIFKNCYLYNPEGHEVNRCGKLLEDIF 889
            KK  L   +K C  I+ ++ SKK+      F +PVD E L LHDY DI+K+PMD+  +KNKL +  Y S  EFA DI+L+F NCY YNP  H+V +  + L+D+F
Sbjct:  279 KKKPLTEQLKYCSTILKDMFSKKHYAYAWPFYKPVDAEALGLHDYHDIIKQPMDMTEIKNKLENRAYDSPSEFAADIRLMFSNCYRYNPPDHDVVKMARQLQDVF 383          

HSP 2 Score: 89.3521 bits (220), Expect = 1.678e-18
Identity = 44/106 (41.51%), Postives = 63/106 (59.43%), Query Frame = 2
Query:   41 TNQLLYIKKNVINVLLRNSNSESFKVPVNPELLGIPNYPDIIKYPMDFGTIKIKLDKQVYQSANECKSDFLSVFRNCYIFNEPGSLYVDMALKLENLFKRKMTDLP 358
            TNQL ++ K V+  L R+ ++  F+ PV+   L +P+Y  IIK PMD GTIK KL+   Y  A EC  DF  +  NCY +N+PG   V M   ++ LF +K+  +P
Sbjct:   16 TNQLQFLLKTVLKGLWRHHHAWPFREPVDAVKLNLPDYHTIIKKPMDLGTIKKKLENNEYPCAQECIEDFRLMINNCYTYNKPGDDIVLMCQSMDKLFHQKIAMMP 121          

HSP 3 Score: 71.633 bits (174), Expect = 6.890e-13
Identity = 40/110 (36.36%), Postives = 61/110 (55.45%), Query Frame = 2
Query:   35 PYTNQLLYIKKNVINVLLRN--SNSESFKVPVNPELLGIPNYPDIIKYPMDFGTIKIKLDKQVYQSANECKSDFLSVFRNCYIFNEPGSLYVDMALKLENLFKRKMTDLP 358
            P T QL Y    + ++  +   + +  F  PV+ E LG+ +Y DIIK PMD   IK KL+ + Y S +E  +D   +F NCY +N P    V MA +L+++F+ K   +P
Sbjct:  282 PLTEQLKYCSTILKDMFSKKHYAYAWPFYKPVDAEALGLHDYHDIIKQPMDMTEIKNKLENRAYDSPSEFAADIRLMFSNCYRYNPPDHDVVKMARQLQDVFEMKFAKMP 391          

HSP 4 Score: 69.707 bits (169), Expect = 2.992e-12
Identity = 33/77 (42.86%), Postives = 46/77 (59.74%), Query Frame = 2
Query:  665 FLEPVDVEGLKLHDYFDIVKKPMDLGTVKNKLFDGFYQSNDEFAEDIKLIFKNCYLYNPEGHEVNRCGKLLEDIFNK 895
            F EPVD   L L DY  I+KKPMDLGT+K KL +  Y    E  ED +L+  NCY YN  G ++    + ++ +F++
Sbjct:   39 FREPVDAVKLNLPDYHTIIKKPMDLGTIKKKLENNEYPCAQECIEDFRLMINNCYTYNKPGDDIVLMCQSMDKLFHQ 115          
BLAST of Bromodomain-containing protein 2 vs. Ensembl Nematostella
Match: EDO45194 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RTD9])

HSP 1 Score: 72.7886 bits (177), Expect = 5.302e-13
Identity = 35/101 (34.65%), Postives = 57/101 (56.44%), Query Frame = 2
Query:  572 FKKSKLEIDIKICKHIILNLVSKKYGDLN--RYFLEPVDVEGLKLHDYFDIVKKPMDLGTVKNKLFDGFYQSNDEFAEDIKLIFKNCYLYNPEGHEV-NRC 865
            + +  L +  K+C +     + ++ GD++   +FL PVD        Y+ +++ PMD GTVK+KL  G Y     F +D+ L+  NC+ YNP+GH+V N C
Sbjct: 1184 WVRGALSLLQKVCGY---RGIGRRKGDVSAASWFLRPVDPN--DAPGYYKVIRTPMDFGTVKHKLESGVYDDYSAFHDDMMLVKNNCFCYNPQGHDVRNDC 1279          
BLAST of Bromodomain-containing protein 2 vs. Ensembl Nematostella
Match: EDO44902 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RUH0])

HSP 1 Score: 64.6994 bits (156), Expect = 3.578e-12
Identity = 30/75 (40.00%), Postives = 47/75 (62.67%), Query Frame = 2
Query:  665 FLEPVDVEGLKLHDYFDIVKKPMDLGTVKNKLFDGFYQSNDEFAEDIKLIFKNCYLYNPEGHEVNRCGKLLEDIF 889
            FLEPV   GL +  Y+D++K+PMDL TV++K+    Y + ++F  D+  IF NC  +N +     RC ++LE +F
Sbjct:   72 FLEPV--SGLDVPGYYDVIKEPMDLSTVEDKITSKKYATLEQFVSDVTRIFDNCRFFNGKDTPYYRCAEVLEAVF 144          

HSP 2 Score: 51.2174 bits (121), Expect = 1.572e-7
Identity = 33/104 (31.73%), Postives = 52/104 (50.00%), Query Frame = 2
Query:   35 PYTNQLLYIKKNVINVLLRNSNSESFKVPVNPELLGIPNYPDIIKYPMDFGTIKIKLDKQVYQSANECKSDFLSVFRNCYIFNEPGSLYVDMALKLENLFKRKM 346
            P TN+     K ++  L  +  +  F  PV+   L +P Y D+IK PMD  T++ K+  + Y +  +  SD   +F NC  FN   + Y   A  LE +F +K+
Sbjct:   47 PLTNRDHDSLKRMLRSLQSHKMAWPFLEPVSG--LDVPGYYDVIKEPMDLSTVEDKITSKKYATLEQFVSDVTRIFDNCRFFNGKDTPYYRCAEVLEAVFVQKL 148          
BLAST of Bromodomain-containing protein 2 vs. Ensembl Nematostella
Match: EDO44814 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RUU7])

HSP 1 Score: 64.3142 bits (155), Expect = 7.149e-11
Identity = 52/187 (27.81%), Postives = 86/187 (45.99%), Query Frame = 2
Query:  341 KMTDLPVPEHYVQDSTFHTPXXXXXXXXXXXXFHTPNVKPNRLTGNTMNSIAKSDISINQKRVRSESNNGYTKEEPLFKKSKLEIDIKICKHIILNLVSKKYGDLNRYFLEPVDVEGLKLHDYFDIVKKPMDLGTVKNKLFDGFYQSNDEFAEDIKLIFKNCYLYNPEGHEVNRCGKLLEDIFNKLY 901
            K+T +P  + Y  D     P          +       K +R T +   S+   D  ++Q     E +N  T+      + +   D+  C+ I+  +  +K+ D    FL PV+ +  +  +Y+ I++KPMD  T+K KL D  Y S  EFA+D +L+F NC  +N +  EV + GK L   F   +
Sbjct:  132 KLTTIPEGDWYCMD-CIELPLEVSGTTASQVSDQKQLEKHSRHTWSIQYSLRDIDFEMSQDGEDEEGDNQETRHH--INRKQQSKDMAPCRTILAEM--EKHDDAWP-FLIPVNAK--QFPEYYKIIRKPMDFHTMKIKLRDYQYSSPQEFAQDSRLVFANCEEFNEDDSEVGQAGKRLSKFFESRW 310          

HSP 2 Score: 55.4546 bits (132), Expect = 5.331e-8
Identity = 33/97 (34.02%), Postives = 49/97 (50.52%), Query Frame = 2
Query:   65 KNVINVLLRNSNSESFKVPVNPELLGIPNYPDIIKYPMDFGTIKIKLDKQVYQSANECKSDFLSVFRNCYIFNEPGSLYVDMALKLENLFKRKMTDL 355
            + ++  + ++ ++  F +PVN +    P Y  II+ PMDF T+KIKL    Y S  E   D   VF NC  FNE  S       +L   F+ + +DL
Sbjct:  219 RTILAEMEKHDDAWPFLIPVNAK--QFPEYYKIIRKPMDFHTMKIKLRDYQYSSPQEFAQDSRLVFANCEEFNEDDSEVGQAGKRLSKFFESRWSDL 313          
BLAST of Bromodomain-containing protein 2 vs. Ensembl Nematostella
Match: EDO40753 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S640])

HSP 1 Score: 63.929 bits (154), Expect = 3.057e-10
Identity = 33/73 (45.21%), Postives = 47/73 (64.38%), Query Frame = 2
Query:  665 FLEPVDVEGLKLHDYFDIVKKPMDLGTVKNKLFDGFYQSNDEFAEDIKLIFKNCYLYNPEGHEVNR-CGKLLE 880
            F  PVD + L   DYF+IV+ PMDL T+K KL +G Y++  E+ +D+ L+F N +LYN +   V + C KL E
Sbjct:  691 FRSPVDPKLLGCLDYFEIVRNPMDLSTIKRKLDNGQYKNPWEYCDDVWLMFDNAWLYNRKTSRVYKYCTKLSE 763          

HSP 2 Score: 55.4546 bits (132), Expect = 1.092e-7
Identity = 28/79 (35.44%), Postives = 45/79 (56.96%), Query Frame = 2
Query:  110 FKVPVNPELLGIPNYPDIIKYPMDFGTIKIKLDKQVYQSANECKSDFLSVFRNCYIFNEPGSLYVDMALKLENLFKRKM 346
            F+ PV+P+LLG  +Y +I++ PMD  TIK KLD   Y++  E   D   +F N +++N   S       KL  +F+ ++
Sbjct:  691 FRSPVDPKLLGCLDYFEIVRNPMDLSTIKRKLDNGQYKNPWEYCDDVWLMFDNAWLYNRKTSRVYKYCTKLSEVFESEI 769          
BLAST of Bromodomain-containing protein 2 vs. Ensembl Medaka
Match: ENSORLT00000017454.2 (bromodomain-containing protein 3 [Source:NCBI gene;Acc:101155101])

HSP 1 Score: 162.155 bits (409), Expect = 3.186e-40
Identity = 105/330 (31.82%), Postives = 161/330 (48.79%), Query Frame = 2
Query:   41 TNQLLYIKKNVINVLLRNSNSESFKVPVNPELLGIPNYPDIIKYPMDFGTIKIKLDKQVYQSANECKSDFLSVFRNCYIFNEPGSLYVDMALKLENLFKRKMTDLPVPEHYV---QDSTFHTPXXXXXXXXXXXXFHTPNVKPNRLTGNTMNSI-AKSDISINQKR-----------VRSESNNG--YTKEE-----PLFKKS---------------------KLEIDIKICKHIILNLVSKKYGDLNRYFLEPVDVEGLKLHDYFDIVKKPMDLGTVKNKLFDGFYQSNDEFAEDIKLIFKNCYLYNPEGHEVNRCGKLLEDIFNKLY 901
            TNQLLY+++ VI  L R+  S  F+ PV+   L IP+Y  +IK+PMD GT+  +L  + Y  ANEC  D  ++F NCY++N PG   V MA  LE +F +K++ +P  E      +D         +      I      V  N +  NT   + A++D ++N K+           V +  + G  +  EE     PL  ++                     +L   ++ C +I+  ++SK++      F  PVD   L L DY DI+K+PMDL T+K K+    Y +  EFA D++L+F NCY YNP  H V    + L+++F   Y
Sbjct:   30 TNQLLYLERVVIKALWRHQYSWPFRQPVDAVALCIPDYYKLIKHPMDLGTVMQRLKNRYYWEANECIKDISTMFNNCYVYNRPGDDIVFMAQTLEKIFLQKVSQMPKEEVIATLPKDEPEKEEPVKQRPVVSEIALQEATVLSNGVHLNTPTRLCAQTDSTLNIKKCLKKKMVSGTPVTATLSRGDEFAAEEHSASIPLISRTGSGRPVKPPKKNLDMFEDKRVRLTEKLRDCNNILKEMLSKRHCAYAWPFYTPVDAIALGLQDYHDIIKQPMDLSTIKKKMDHQEYTNATEFAADVRLMFSNCYRYNPPSHGVVYMARKLQEVFEARY 359          
BLAST of Bromodomain-containing protein 2 vs. Ensembl Medaka
Match: brd4 (bromodomain-containing protein 4 [Source:NCBI gene;Acc:101158947])

HSP 1 Score: 106.301 bits (264), Expect = 9.322e-23
Identity = 44/97 (45.36%), Postives = 62/97 (63.92%), Query Frame = 2
Query:  599 IKICKHIILNLVSKKYGDLNRYFLEPVDVEGLKLHDYFDIVKKPMDLGTVKNKLFDGFYQSNDEFAEDIKLIFKNCYLYNPEGHEVNRCGKLLEDIF 889
            +  C  ++  ++SKK+      F +PVDV+ L LHDY DI+K PMDL T+K KL +  Y+   EFA D++L+F NCY YNP  HEV    + L+D+F
Sbjct:  357 LGYCAALVREMLSKKHAAYAWPFYKPVDVDALGLHDYHDIIKHPMDLSTIKAKLENRQYRDPQEFAADVRLMFSNCYKYNPPDHEVVAMARKLQDVF 453          

HSP 2 Score: 98.2117 bits (243), Expect = 3.036e-20
Identity = 47/106 (44.34%), Postives = 68/106 (64.15%), Query Frame = 2
Query:   41 TNQLLYIKKNVINVLLRNSNSESFKVPVNPELLGIPNYPDIIKYPMDFGTIKIKLDKQVYQSANECKSDFLSVFRNCYIFNEPGSLYVDMALKLENLFKRKMTDLP 358
            TNQL Y+ K V+  L ++  S  F+ PV+   L +P+Y  II  PMD GTIK +L+   Y +A EC  DF ++F NCYI+N+PG   V MA  LE +F +K++++P
Sbjct:   39 TNQLQYLLKVVVKALWKHHFSWPFQAPVDAIKLNLPDYYTIIHTPMDLGTIKKRLENSYYWNAQECIQDFNTMFTNCYIYNKPGDDIVLMAEALEKVFLQKVSEMP 144          

HSP 3 Score: 74.3294 bits (181), Expect = 5.142e-13
Identity = 44/116 (37.93%), Postives = 65/116 (56.03%), Query Frame = 2
Query:   44 NQLLYIKKNVINVLLRNSNSES--FKVPVNPELLGIPNYPDIIKYPMDFGTIKIKLDKQVYQSANECKSDFLSVFRNCYIFNEPGSLYVDMALKLENLFK---RKMTDLPVPEHYV 376
            +QL Y    V  +L +   + +  F  PV+ + LG+ +Y DIIK+PMD  TIK KL+ + Y+   E  +D   +F NCY +N P    V MA KL+++F+    KM D P  +H V
Sbjct:  355 DQLGYCAALVREMLSKKHAAYAWPFYKPVDVDALGLHDYHDIIKHPMDLSTIKAKLENRQYRDPQEFAADVRLMFSNCYKYNPPDHEVVAMARKLQDVFEMRFAKMPDEPESKHVV 470          

HSP 4 Score: 72.0182 bits (175), Expect = 2.925e-12
Identity = 30/75 (40.00%), Postives = 44/75 (58.67%), Query Frame = 2
Query:  665 FLEPVDVEGLKLHDYFDIVKKPMDLGTVKNKLFDGFYQSNDEFAEDIKLIFKNCYLYNPEGHEVNRCGKLLEDIF 889
            F  PVD   L L DY+ I+  PMDLGT+K +L + +Y +  E  +D   +F NCY+YN  G ++    + LE +F
Sbjct:   62 FQAPVDAIKLNLPDYYTIIHTPMDLGTIKKRLENSYYWNAQECIQDFNTMFTNCYIYNKPGDDIVLMAEALEKVF 136          
BLAST of Bromodomain-containing protein 2 vs. Ensembl Medaka
Match: brd4 (bromodomain-containing protein 4 [Source:NCBI gene;Acc:101158947])

HSP 1 Score: 105.916 bits (263), Expect = 1.135e-22
Identity = 44/97 (45.36%), Postives = 62/97 (63.92%), Query Frame = 2
Query:  599 IKICKHIILNLVSKKYGDLNRYFLEPVDVEGLKLHDYFDIVKKPMDLGTVKNKLFDGFYQSNDEFAEDIKLIFKNCYLYNPEGHEVNRCGKLLEDIF 889
            +  C  ++  ++SKK+      F +PVDV+ L LHDY DI+K PMDL T+K KL +  Y+   EFA D++L+F NCY YNP  HEV    + L+D+F
Sbjct:  443 LGYCAALVREMLSKKHAAYAWPFYKPVDVDALGLHDYHDIIKHPMDLSTIKAKLENRQYRDPQEFAADVRLMFSNCYKYNPPDHEVVAMARKLQDVF 539          

HSP 2 Score: 98.2117 bits (243), Expect = 2.667e-20
Identity = 47/106 (44.34%), Postives = 68/106 (64.15%), Query Frame = 2
Query:   41 TNQLLYIKKNVINVLLRNSNSESFKVPVNPELLGIPNYPDIIKYPMDFGTIKIKLDKQVYQSANECKSDFLSVFRNCYIFNEPGSLYVDMALKLENLFKRKMTDLP 358
            TNQL Y+ K V+  L ++  S  F+ PV+   L +P+Y  II  PMD GTIK +L+   Y +A EC  DF ++F NCYI+N+PG   V MA  LE +F +K++++P
Sbjct:  125 TNQLQYLLKVVVKALWKHHFSWPFQAPVDAIKLNLPDYYTIIHTPMDLGTIKKRLENSYYWNAQECIQDFNTMFTNCYIYNKPGDDIVLMAEALEKVFLQKVSEMP 230          

HSP 3 Score: 74.7146 bits (182), Expect = 4.639e-13
Identity = 44/116 (37.93%), Postives = 65/116 (56.03%), Query Frame = 2
Query:   44 NQLLYIKKNVINVLLRNSNSES--FKVPVNPELLGIPNYPDIIKYPMDFGTIKIKLDKQVYQSANECKSDFLSVFRNCYIFNEPGSLYVDMALKLENLFK---RKMTDLPVPEHYV 376
            +QL Y    V  +L +   + +  F  PV+ + LG+ +Y DIIK+PMD  TIK KL+ + Y+   E  +D   +F NCY +N P    V MA KL+++F+    KM D P  +H V
Sbjct:  441 DQLGYCAALVREMLSKKHAAYAWPFYKPVDVDALGLHDYHDIIKHPMDLSTIKAKLENRQYRDPQEFAADVRLMFSNCYKYNPPDHEVVAMARKLQDVFEMRFAKMPDEPESKHVV 556          

HSP 4 Score: 72.0182 bits (175), Expect = 3.232e-12
Identity = 30/75 (40.00%), Postives = 44/75 (58.67%), Query Frame = 2
Query:  665 FLEPVDVEGLKLHDYFDIVKKPMDLGTVKNKLFDGFYQSNDEFAEDIKLIFKNCYLYNPEGHEVNRCGKLLEDIF 889
            F  PVD   L L DY+ I+  PMDLGT+K +L + +Y +  E  +D   +F NCY+YN  G ++    + LE +F
Sbjct:  148 FQAPVDAIKLNLPDYYTIIHTPMDLGTIKKRLENSYYWNAQECIQDFNTMFTNCYIYNKPGDDIVLMAEALEKVF 222          
BLAST of Bromodomain-containing protein 2 vs. Ensembl Medaka
Match: brd4 (bromodomain-containing protein 4 [Source:NCBI gene;Acc:101158947])

HSP 1 Score: 105.916 bits (263), Expect = 1.140e-22
Identity = 44/97 (45.36%), Postives = 62/97 (63.92%), Query Frame = 2
Query:  599 IKICKHIILNLVSKKYGDLNRYFLEPVDVEGLKLHDYFDIVKKPMDLGTVKNKLFDGFYQSNDEFAEDIKLIFKNCYLYNPEGHEVNRCGKLLEDIF 889
            +  C  ++  ++SKK+      F +PVDV+ L LHDY DI+K PMDL T+K KL +  Y+   EFA D++L+F NCY YNP  HEV    + L+D+F
Sbjct:  357 LGYCAALVREMLSKKHAAYAWPFYKPVDVDALGLHDYHDIIKHPMDLSTIKAKLENRQYRDPQEFAADVRLMFSNCYKYNPPDHEVVAMARKLQDVF 453          

HSP 2 Score: 98.2117 bits (243), Expect = 2.929e-20
Identity = 47/106 (44.34%), Postives = 68/106 (64.15%), Query Frame = 2
Query:   41 TNQLLYIKKNVINVLLRNSNSESFKVPVNPELLGIPNYPDIIKYPMDFGTIKIKLDKQVYQSANECKSDFLSVFRNCYIFNEPGSLYVDMALKLENLFKRKMTDLP 358
            TNQL Y+ K V+  L ++  S  F+ PV+   L +P+Y  II  PMD GTIK +L+   Y +A EC  DF ++F NCYI+N+PG   V MA  LE +F +K++++P
Sbjct:   39 TNQLQYLLKVVVKALWKHHFSWPFQAPVDAIKLNLPDYYTIIHTPMDLGTIKKRLENSYYWNAQECIQDFNTMFTNCYIYNKPGDDIVLMAEALEKVFLQKVSEMP 144          

HSP 3 Score: 74.3294 bits (181), Expect = 5.107e-13
Identity = 44/116 (37.93%), Postives = 65/116 (56.03%), Query Frame = 2
Query:   44 NQLLYIKKNVINVLLRNSNSES--FKVPVNPELLGIPNYPDIIKYPMDFGTIKIKLDKQVYQSANECKSDFLSVFRNCYIFNEPGSLYVDMALKLENLFK---RKMTDLPVPEHYV 376
            +QL Y    V  +L +   + +  F  PV+ + LG+ +Y DIIK+PMD  TIK KL+ + Y+   E  +D   +F NCY +N P    V MA KL+++F+    KM D P  +H V
Sbjct:  355 DQLGYCAALVREMLSKKHAAYAWPFYKPVDVDALGLHDYHDIIKHPMDLSTIKAKLENRQYRDPQEFAADVRLMFSNCYKYNPPDHEVVAMARKLQDVFEMRFAKMPDEPESKHVV 470          

HSP 4 Score: 71.633 bits (174), Expect = 3.386e-12
Identity = 30/75 (40.00%), Postives = 44/75 (58.67%), Query Frame = 2
Query:  665 FLEPVDVEGLKLHDYFDIVKKPMDLGTVKNKLFDGFYQSNDEFAEDIKLIFKNCYLYNPEGHEVNRCGKLLEDIF 889
            F  PVD   L L DY+ I+  PMDLGT+K +L + +Y +  E  +D   +F NCY+YN  G ++    + LE +F
Sbjct:   62 FQAPVDAIKLNLPDYYTIIHTPMDLGTIKKRLENSYYWNAQECIQDFNTMFTNCYIYNKPGDDIVLMAEALEKVF 136          
BLAST of Bromodomain-containing protein 2 vs. Ensembl Medaka
Match: ENSORLT00000012942.2 (bromodomain-containing protein 4 [Source:NCBI gene;Acc:101159647])

HSP 1 Score: 105.531 bits (262), Expect = 1.571e-22
Identity = 50/106 (47.17%), Postives = 70/106 (66.04%), Query Frame = 2
Query:   41 TNQLLYIKKNVINVLLRNSNSESFKVPVNPELLGIPNYPDIIKYPMDFGTIKIKLDKQVYQSANECKSDFLSVFRNCYIFNEPGSLYVDMALKLENLFKRKMTDLP 358
            TNQL Y+ K V+  L ++  +  F+ PV+   LG+P+Y  IIK PMD GTIK +L+   Y +A EC  DF ++F NCYI+N+PG   V MA  LE LF +K+T++P
Sbjct:   39 TNQLQYLHKVVLKTLWKHHFAWPFQAPVDAVKLGLPDYYKIIKTPMDMGTIKKRLENNYYWNAQECIQDFNTMFTNCYIYNKPGDDIVLMAEALEKLFLQKITEMP 144          

HSP 2 Score: 105.145 bits (261), Expect = 1.878e-22
Identity = 44/103 (42.72%), Postives = 65/103 (63.11%), Query Frame = 2
Query:  581 SKLEIDIKICKHIILNLVSKKYGDLNRYFLEPVDVEGLKLHDYFDIVKKPMDLGTVKNKLFDGFYQSNDEFAEDIKLIFKNCYLYNPEGHEVNRCGKLLEDIF 889
            SK +  ++ C  ++  ++SKK+      F +PVD + L LHDY DI+K PMDL T+K KL +  Y+   EFA D++L+F NCY YNP  H+V    + L+D+F
Sbjct:  428 SKRQEQLRFCARLLKEMLSKKHVAYAWPFYKPVDAKALGLHDYHDIIKHPMDLSTIKKKLDNRQYRDAQEFAADVRLMFSNCYKYNPPDHDVVSMARKLQDVF 530          

HSP 3 Score: 77.0258 bits (188), Expect = 8.148e-14
Identity = 36/83 (43.37%), Postives = 52/83 (62.65%), Query Frame = 2
Query:  110 FKVPVNPELLGIPNYPDIIKYPMDFGTIKIKLDKQVYQSANECKSDFLSVFRNCYIFNEPGSLYVDMALKLENLFKRKMTDLP 358
            F  PV+ + LG+ +Y DIIK+PMD  TIK KLD + Y+ A E  +D   +F NCY +N P    V MA KL+++F+ +   +P
Sbjct:  456 FYKPVDAKALGLHDYHDIIKHPMDLSTIKKKLDNRQYRDAQEFAADVRLMFSNCYKYNPPDHDVVSMARKLQDVFEMRFAKMP 538          

HSP 4 Score: 73.1738 bits (178), Expect = 1.304e-12
Identity = 30/75 (40.00%), Postives = 45/75 (60.00%), Query Frame = 2
Query:  665 FLEPVDVEGLKLHDYFDIVKKPMDLGTVKNKLFDGFYQSNDEFAEDIKLIFKNCYLYNPEGHEVNRCGKLLEDIF 889
            F  PVD   L L DY+ I+K PMD+GT+K +L + +Y +  E  +D   +F NCY+YN  G ++    + LE +F
Sbjct:   62 FQAPVDAVKLGLPDYYKIIKTPMDMGTIKKRLENNYYWNAQECIQDFNTMFTNCYIYNKPGDDIVLMAEALEKLF 136          
BLAST of Bromodomain-containing protein 2 vs. Planmine SMEST
Match: SMESG000012934.1 (SMESG000012934.1)

HSP 1 Score: 1458.74 bits (3775), Expect = 0.000e+0
Identity = 773/789 (97.97%), Postives = 773/789 (97.97%), Query Frame = 2
Query:   26 MEYPYTNQLLYIKKNVINVLLRNSNSESFKVPVNPELLGIPNYPDIIKYPMDFGTIKIKLDKQVYQSANECKSDFLSVFRNCYIFNEPGSLYVDMALKLENLFKRKMTDLPVPEHYVQDSTFHTPXXXXXXXXXXXXFHTPNVKPNRLTGNTMNSIAKSDISINQKRVRSESNNGYTKEEPLFKKSKLEIDIKICKHIILNLVSKKYGDLNRYFLEPVDVEGLKLHDYFDIVKKPMDLGTVKNKLFDGFYQSNDEFAEDIKLIFKNCYLYNPEGHEVNRCGKLLEDIFNKLYQGAFGNSKITSKPTRTQHRSYDDLQPLLQKILKRQAEIDNMHMDIIKRNIEIQQSIDFINGTELIKSIKASVNINSKQSNASSKRAFYNTTNGDTKLEKNFSPKPDIVRQISKVEQKSESYISKLYMNNPNVLNKPSEIQKSPKPAIPKHDPHKEVSNRPIEAKRTIKPTYKSQPSINDEISKPIAKRPLNHISNHVSTDNHISSNDLPNPIEPLTKPTPETFKPDTKKPTKNAEEYSVKLKEIKSWISSLSPEMSMKIREFINKSENRNVVSVSLMKLKPSTINGLYKMMTEPIKEPEKVESKSDLKEFTIEDRMQLSQDLRLLGDKCSEKILNIYKKTEDVQSSDGECEIDFQTMKLVTLHSLREFADKCLQKKREKQLKKCAVTAGQPVGNNGXXXXXXXXXXXXXXXXXXXXXXXXXXXXNELFNNLXXXXXXXXXXXXXXXXXRSNFTPKIPPEIVSKPLVDLQTVTTISIPQLSSSSEKVNIDNTQEGSRL 2392
            MEYPYTNQLLYIKKNVINVLLRNSNSESFKVPVNPELLGIPNYPDIIKYPMDFGTIKIKLDKQVYQSANECKSDFLSVFRNCYIFNEPGSLYVDMALKLENLFKRKMTDLPVPEHYVQDSTFHTPKSTKVKKGKSIKFHTPNVKPNRLTGNTMNSIAKSDISINQKRVRSESNNGYTKEEPLFKKSKLEIDIKICKHIILNLVSKKYGDLNRYFLEPVDVEGLKLHDYFDIVKKPMDLGTVKNKLFDGFYQSNDEFAEDIKLIFKNCYLYNPEGHEVNRCGKLLEDIFNKLYQGAFGNSKITSKPTRTQHRSYDDLQPLLQKILKRQAEID MHMDIIKRNIEIQQSIDFINGTELIKSIKASVNINSKQSNASSKRAFYNTTNGDTKLEKNFSPKPDIVRQISKVEQKSESYISKLYMNNPNVLNKPSEIQKSPKPAIPKHDPHKEVSNRPIEAKRTIKPTYKSQPSINDEISKPIAKRPLNHISNHVSTDNHISSNDLPNPIEPLTKPTPETFKPDTKKPTKNAEEYSVKLKEIKSWISSLSPEMSMKIREFINKSENRNVVSVSLMKLKPSTINGLYKMMTEPIKEPEKVESKSDLKEFTIEDRMQLSQDLRLLGDKCSEKILNIYKKTEDVQSSDGECEIDFQTMKLVTLHSLREFADKCLQKKREKQLKKCAVTAGQPVGNNGDISDSDSSDSSDSDGSDSNSDASTSSSDNELFNNL               SIRSNFTPKIPPEIVSKPLVDLQTVTTISIPQLSSSSEKVNIDNTQEGSRL
Sbjct:    1 MEYPYTNQLLYIKKNVINVLLRNSNSESFKVPVNPELLGIPNYPDIIKYPMDFGTIKIKLDKQVYQSANECKSDFLSVFRNCYIFNEPGSLYVDMALKLENLFKRKMTDLPVPEHYVQDSTFHTPKSTKVKKGKSIKFHTPNVKPNRLTGNTMNSIAKSDISINQKRVRSESNNGYTKEEPLFKKSKLEIDIKICKHIILNLVSKKYGDLNRYFLEPVDVEGLKLHDYFDIVKKPMDLGTVKNKLFDGFYQSNDEFAEDIKLIFKNCYLYNPEGHEVNRCGKLLEDIFNKLYQGAFGNSKITSKPTRTQHRSYDDLQPLLQKILKRQAEIDKMHMDIIKRNIEIQQSIDFINGTELIKSIKASVNINSKQSNASSKRAFYNTTNGDTKLEKNFSPKPDIVRQISKVEQKSESYISKLYMNNPNVLNKPSEIQKSPKPAIPKHDPHKEVSNRPIEAKRTIKPTYKSQPSINDEISKPIAKRPLNHISNHVSTDNHISSNDLPNPIEPLTKPTPETFKPDTKKPTKNAEEYSVKLKEIKSWISSLSPEMSMKIREFINKSENRNVVSVSLMKLKPSTINGLYKMMTEPIKEPEKVESKSDLKEFTIEDRMQLSQDLRLLGDKCSEKILNIYKKTEDVQSSDGECEIDFQTMKLVTLHSLREFADKCLQKKREKQLKKCAVTAGQPVGNNGDISDSDSSDSSDSDGSDSNSDASTSSSDNELFNNL---------------SIRSNFTPKIPPEIVSKPLVDLQTVTTISIPQLSSSSEKVNIDNTQEGSRL 774          
BLAST of Bromodomain-containing protein 2 vs. Planmine SMEST
Match: SMESG000075694.1 (SMESG000075694.1)

HSP 1 Score: 196.823 bits (499), Expect = 1.829e-52
Identity = 147/435 (33.79%), Postives = 223/435 (51.26%), Query Frame = 2
Query:   41 TNQLLYIKKNVINVLLRNSNSESFKVPVNPELLGIPNYPDIIKYPMDFGTIKIKLDKQVYQSANECKSDFLSVFRNCYIFNEPGSLYVDMALKLENLFKRKMTDLPVPEHYVQDSTFHTPXXXXXXXXXXXXFHTPNVKPN------RLTGNT----MNSIAKSDISIN------QKRVRSES--------------NNGYTKEEPLFKKSKLEIDIKICKHIILNLVSKKYGDLNRYFLEPVDVEGLKLHDYFDIVKKPMDLGTVKNKLFDGFYQSNDEFAEDIKLIFKNCYLYNPEGHEVNRCGKLLEDIFNKLYQGAFGNSK-----ITSKPTRTQHRSYDDLQPLLQKILKRQAEIDNMH----MDIIKRNIEIQQSIDFINGTELIKSIKASVNINSKQSNASSKRAFYNTTNGDTKLEKNFSPKPDIVR 1228
            TN+L +IKK ++  L+R+  S  F  PV+   L IP+YP II YPMDF T+K +L K+ Y +A+EC +D   VF+NCYIFN P    + M L LEN+F  K+  LP  E+ +  S       +      S      ++K +      RL  N+      S   S+ SI+       K+ + ES               N    E P+  K KL  ++K+C +I+ ++ S +Y  LN  F+EPV V    L DY  I+KKPMDL T++  L DG Y++ ++F+ED+KLIF NCY YN +  ++++  K L++IF++L+   F  SK     + +   +++  + D LQ LLQKI K Q  +   H      IIK+N+ I+         EL  ++K     +    N +S   F N+ +   K  KN SP P + +
Sbjct:   31 TNRLQFIKKKILPQLMRHKYSFPFLHPVDHAALNIPDYPKIIHYPMDFTTVKNRLIKKFYYNADECITDIRLVFQNCYIFNPPEIDLISMTLTLENIFNSKLDKLPSQENDISSSNSKKDTKSNSINNDSSSEPVCDIKKSLRPTTKRLKSNSNYNETTSTNASNCSISPDAKSKAKKRKVESCYDLSPTPSPSISLKNESLDEIPI--KPKLSEELKMCSNILRDISSNRYRHLNDMFMEPVAVRFPNLSDYSSIIKKPMDLSTIRKNLDDGSYKTKNDFSEDVKLIFDNCYDYNGKDSDISKLAKDLQNIFDELFSKQFNLSKPQPFQVQNSKIKSESVNEDTLQ-LLQKIHKEQKSLVETHNKVAEKIIKQNLLIR---------ELSSTLKIPFEFDLSLINVNSSAVFANSKSK--KRNKNLSPSPIMAK 451          
BLAST of Bromodomain-containing protein 2 vs. Planmine SMEST
Match: SMESG000005406.1 (SMESG000005406.1)

HSP 1 Score: 177.178 bits (448), Expect = 4.782e-46
Identity = 111/306 (36.27%), Postives = 164/306 (53.59%), Query Frame = 2
Query:   35 PYTNQLLYIKKNVINVLLRNSNSESFKVPVNPELLGIPNYPDIIKYPMDFGTIKIKLDKQVYQSANECKSDFLSVFRNCYIFNEPGSLYVDMALKLENLFKRKMTDLPVPEHYVQ-DSTFHTPXXXXXXXXXXXXFHTPNVKPNRLTGNTMNSIAKSDISINQKRVRSESNNGYTKEEPLFKKSK--------LEIDIKICKHIILNLVSKKYGDLNRYFLEPVDVEGLKLHDYFDIVKKPMDLGTVKNKLFDGFYQSNDEFAEDIKLIFKNCYLYNPEGHEVNRCGKLLEDIFNKLYQGAFGNSK 925
            P TN L YI K V+  LL++  +  F   V+   L IP+YP II+ PMDF  +K KL  + Y S  EC  D   VF NCY+FN+PG   + MALKL+++FK K+  + +  +    +S   TP S +           P +KP  +   + NS+         KR   E     + + P  + SK        L  D+  C +I+ +++S KY  LN  FL PVDV+   LH+YF+I+KKPMD  T+K+KL    Y++ ++F ED++L+F NC ++N E HE  +  K L +IF +L    F  +K
Sbjct:    7 PPTNSLEYINKTVLPSLLKHKFAWPFTKAVDIVALNIPDYPKIIRQPMDFSLVKSKLRNKQYSSIYECIDDVNRVFCNCYLFNQPGEDVIFMALKLDSIFKEKIKHMALDNYAPSLNSRVSTPISNQSNS-----ISIP-IKPKEMENLSTNSLL-------GKRKLEEDTEKLSCKLPRMETSKIVKDTPSFLNSDLSKCLNILKDIMSSKYRKLNGLFLLPVDVKKYNLHNYFEIIKKPMDFTTIKSKLEANLYENKEKFIEDVELVFNNCTIFNGELHEYAKIAKTLNEIFKELCTKTFSTNK 299          
BLAST of Bromodomain-containing protein 2 vs. Planmine SMEST
Match: SMESG000040270.1 (SMESG000040270.1)

HSP 1 Score: 167.162 bits (422), Expect = 2.634e-42
Identity = 102/319 (31.97%), Postives = 165/319 (51.72%), Query Frame = 2
Query:   41 TNQLLYIKKNVINVLLRNSNSESFKVPVNPELLGIPNYPDIIKYPMDFGTIKIKLDKQVYQSANECKSDFLSVFRNCYIFNEPGSLYVDMALKLENLFKRKMTDLPVPEHYVQDSTFHTPXXXXXXXXXXXXFHTPNVKPNRLTGNTMNSIAKSDISINQ--------------KRVRSESNNGYTKEEPLF--------------KKSKLEIDIKICKHIILNLVSKKYGDLNRYFLEPVDVEGLKLHDYFDIVKKPMDLGTVKNKLFDGFYQSNDEFAEDIKLIFKNCYLYNPEGHEVNRCGKLLEDIFNKLYQGAF 913
            TN+L YIKK +I V+L+N ++  F   V+   L +P+YP+IIK PMD   IK++L ++ Y+ A++C  D   +F NCYI+N PG+  V+MA  LE L + K+  +P+ E+ V  +                  H    K  R+  +  +   KS +   Q               ++ S  +   T   P+F              K+ +L  D+++C  ++  +++ +Y  LN  FLEPV  +   L DY  I+K P+DLGT+K+KL +  Y++ DEF  D++L+F NCY YN    +V+R  + L+ IF++ Y   F
Sbjct:   22 TNKLEYIKKQIIPVILKNPHAYPFAKAVDYINLNLPDYPEIIKGPMDISKIKVRLAQKYYRRASDCIQDLFQIFCNCYIYNPPGTDIVNMARALEILTREKLKMMPIEEYEVVSTKVK---------------HEDGSKKGRIANHKSD---KSSVGSPQNSVSSSKAASSAKRAKIDSCYDMSPTPSPPIFKSKLKSEFSDDHHLKRPRLSDDLRLCAALLKEIMAVRYRHLNEMFLEPVTQKFPSLKDYLSIIKNPIDLGTIKDKLENYQYKTKDEFLNDVQLMFNNCYAYNGMESDVSRLARDLQKIFDEAYSKQF 322          
BLAST of Bromodomain-containing protein 2 vs. Planmine SMEST
Match: SMESG000080341.1 (SMESG000080341.1)

HSP 1 Score: 115.161 bits (287), Expect = 3.539e-27
Identity = 103/361 (28.53%), Postives = 168/361 (46.54%), Query Frame = 2
Query:   35 PYTNQLLYIKKNVINVLLRNSNSESFKVPVNPELLGIPNYPDIIKYPMDFGTIKIKLDKQVYQSANECKSDFLSVFRNCYIFNEPGSLYVDMALKLENLFKRKMTDLPVPEHYVQDSTFHTPXXXXXXXXXXXXFHTPNVKPNRLTGNTMNSIAKSDISINQKRVRSESNNGYTKEEPLFKKSKLEIDIKICKHIILNLVSKKYGDLNRYFLEPVDVEGLKLHDYFDIVKKPMDLGTVKNKLFDGFYQSNDEFAEDIKLIFKNCYLYNPEGHEVNRCGKLLEDIFNKLYQGAFGNSKITSKPTRTQHRSYDDLQPLLQKILKRQAEIDNMHMDIIKRNIEIQQS-IDFI-----NGTELIK 1099
            P+TN+L  + K +I  ++R   ++ F  PV+     +P+YP +IK P+D  TIK +L ++ Y++  +C  DF  +  NCYI+N P    + M +KL+   K K+  +P+ E  V++         K K        TP  K             K+ ++++Q  V+  S N  +        S    +   C  +I  L+S KY  +N  FLEPVDV+ L L DY +++K P+DL T++  + +  Y S      DI L+  NC +YN    ++    +  +  F  LY   F          + +    D+    L KI ++  EI+ M + I    I + +S ID I     N  EL+K
Sbjct:   10 PFTNKLDIMLKKIIPFVMRYEAAKPFLKPVDHVAYQLPDYPQVIKSPIDLSTIKERLIRKFYETLGKCLQDFNLMLENCYIYNAPDDPIISMGIKLKLYLKAKLVLMPIDEFKVKN--------LKNKIVPLRSVKTPKQKLK----------IKNFLNVSQSPVKKISENIVSSNYIPLTDS----EYGKCYILINELMSSKYKSINYLFLEPVDVKSLGLSDYHELIKYPIDLSTIQKYMDERLYDSRLAVVNDIYLMINNCNIYNGRQTDIGNICRRFQLEFENLYYSIFKE--------KCRENVNDEAFYFLMKIKRKHKEIEEM-IRINSEKISVSRSRIDMIVNLFENNKELLK 339          
The following BLAST results are available for this feature:
BLAST of Bromodomain-containing protein 2 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5
Match NameE-valueIdentityDescription
BRD42.364e-2344.76bromodomain containing 4 [Source:HGNC Symbol;Acc:H... [more]
BRD44.962e-2344.76bromodomain containing 4 [Source:HGNC Symbol;Acc:H... [more]
BRD45.997e-2344.76bromodomain containing 4 [Source:HGNC Symbol;Acc:H... [more]
BRD27.874e-2345.87bromodomain containing 2 [Source:HGNC Symbol;Acc:H... [more]
BRD48.028e-2344.76bromodomain containing 4 [Source:HGNC Symbol;Acc:H... [more]
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BLAST of Bromodomain-containing protein 2 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 5
Match NameE-valueIdentityDescription
bet-19.865e-3227.84Bromodomain-containing protein bet-1 [Source:UniP... [more]
bet-11.131e-3127.84Bromodomain-containing protein bet-1 [Source:UniP... [more]
F13C5.22.266e-1139.08pep chromosome:WBcel235:X:593960:596289:1 gene:WBG... [more]
bet-21.045e-1033.66BET (Two bromodomains) family protein [Source:Uni... [more]
bet-21.101e-1033.66BET (Two bromodomains) family protein [Source:Uni... [more]
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BLAST of Bromodomain-containing protein 2 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5
Match NameE-valueIdentityDescription
fs(1)h2.000e-2550.93gene:FBgn0004656 transcript:FBtr0333308[more]
fs(1)h2.024e-2550.93gene:FBgn0004656 transcript:FBtr0071122[more]
fs(1)h2.024e-2550.93gene:FBgn0004656 transcript:FBtr0071120[more]
fs(1)h2.024e-2550.93gene:FBgn0004656 transcript:FBtr0071118[more]
fs(1)h2.024e-2550.93gene:FBgn0004656 transcript:FBtr0301309[more]
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BLAST of Bromodomain-containing protein 2 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
brd3b1.141e-2345.45bromodomain containing 3b [Source:ZFIN;Acc:ZDB-GEN... [more]
brd3a2.355e-2346.67bromodomain containing 3a [Source:ZFIN;Acc:ZDB-GEN... [more]
brd3b2.474e-2345.45bromodomain containing 3b [Source:ZFIN;Acc:ZDB-GEN... [more]
brd3a2.944e-2346.67bromodomain containing 3a [Source:ZFIN;Acc:ZDB-GEN... [more]
brd41.312e-2239.84bromodomain containing 4 [Source:NCBI gene;Acc:570... [more]
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BLAST of Bromodomain-containing protein 2 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5
Match NameE-valueIdentityDescription
kif3b3.506e-2344.95kinesin family member 3B [Source:Xenbase;Acc:XB-GE... [more]
kif3b3.516e-2344.95kinesin family member 3B [Source:Xenbase;Acc:XB-GE... [more]
brd35.533e-2346.67bromodomain containing 3 [Source:NCBI gene;Acc:733... [more]
brd28.697e-2344.04bromodomain containing 2 [Source:NCBI gene;Acc:100... [more]
brd29.652e-2344.04bromodomain containing 2 [Source:NCBI gene;Acc:100... [more]
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BLAST of Bromodomain-containing protein 2 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Brd41.389e-2344.76bromodomain containing 4 [Source:MGI Symbol;Acc:MG... [more]
Brd41.436e-2344.76bromodomain containing 4 [Source:MGI Symbol;Acc:MG... [more]
Brd41.922e-2344.76bromodomain containing 4 [Source:MGI Symbol;Acc:MG... [more]
Brd41.987e-2344.76bromodomain containing 4 [Source:MGI Symbol;Acc:MG... [more]
Brd43.021e-2344.76bromodomain containing 4 [Source:MGI Symbol;Acc:MG... [more]
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BLAST of Bromodomain-containing protein 2 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|Q07442|BDF2_YEAST2.733e-3433.33Bromodomain-containing factor 2 OS=Saccharomyces c... [more]
sp|Q5A4W8|BDF1_CANAL2.031e-3330.77Bromodomain-containing factor 1 OS=Candida albican... [more]
sp|P35817|BDF1_YEAST3.039e-3332.13Bromodomain-containing factor 1 OS=Saccharomyces c... [more]
sp|Q9Y7N0|BDF1_SCHPO8.553e-3229.03SWR1 complex bromodomain subunit bdf1 OS=Schizosac... [more]
sp|Q9HGP4|YK82_SCHPO4.985e-3130.96Bromodomain-containing protein C631.02 OS=Schizosa... [more]
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BLAST of Bromodomain-containing protein 2 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
A0A3S5BEG14.511e-5336.16Uncharacterized protein (Fragment) OS=Protopolysto... [more]
A0A0R3X1291.473e-5236.99Uncharacterized protein OS=Hydatigena taeniaeformi... [more]
A0A0X3NGE92.260e-5234.79Bromodomain-containing protein 2 OS=Schistocephalu... [more]
A0A183APR31.055e-5137.20Uncharacterized protein OS=Echinostoma caproni OX=... [more]
A0A2H1CEU61.085e-5136.89Bromodomain protein OS=Fasciola hepatica OX=6192 G... [more]
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BLAST of Bromodomain-containing protein 2 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
ENSAMXT00000057848.16.720e-2345.13pep primary_assembly:Astyanax_mexicanus-2.0:12:831... [more]
BRD39.120e-2345.71bromodomain-containing protein 3-like [Source:NCBI... [more]
BRD39.162e-2345.71bromodomain-containing protein 3-like [Source:NCBI... [more]
brd3a1.031e-2245.71bromodomain-containing protein 3 [Source:NCBI gene... [more]
brdt1.121e-2245.79bromodomain testis-specific protein [Source:NCBI g... [more]
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BLAST of Bromodomain-containing protein 2 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 5
Match NameE-valueIdentityDescription
ENSPMAT00000008098.11.535e-2445.54pep scaffold:Pmarinus_7.0:GL481104:2991:16154:-1 g... [more]
ENSPMAT00000002732.12.843e-2244.76pep scaffold:Pmarinus_7.0:GL482934:3:7597:-1 gene:... [more]
ENSPMAT00000002730.14.952e-2244.76pep scaffold:Pmarinus_7.0:GL482934:3:7765:-1 gene:... [more]
ENSPMAT00000008812.13.207e-2044.04pep scaffold:Pmarinus_7.0:GL478772:7873:35829:1 ge... [more]
ENSPMAT00000006336.11.215e-1347.95pep scaffold:Pmarinus_7.0:GL479543:3524:30791:1 ge... [more]
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BLAST of Bromodomain-containing protein 2 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 4
Match NameE-valueIdentityDescription
BDF23.936e-3633.33Protein involved in transcription initiation; acts... [more]
BDF14.377e-3532.13Protein involved in transcription initiation; func... [more]
GCN52.195e-1033.65Catalytic subunit of ADA and SAGA histone acetyltr... [more]
SPT71.358e-636.08Subunit of the SAGA transcriptional regulatory com... [more]
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BLAST of Bromodomain-containing protein 2 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 5
Match NameE-valueIdentityDescription
EDO318451.013e-2346.67Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO451945.302e-1334.65Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO449023.578e-1240.00Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO448147.149e-1127.81Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO407533.057e-1045.21Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
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BLAST of Bromodomain-containing protein 2 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5
Match NameE-valueIdentityDescription
ENSORLT00000017454.23.186e-4031.82bromodomain-containing protein 3 [Source:NCBI gene... [more]
brd49.322e-2345.36bromodomain-containing protein 4 [Source:NCBI gene... [more]
brd41.135e-2245.36bromodomain-containing protein 4 [Source:NCBI gene... [more]
brd41.140e-2245.36bromodomain-containing protein 4 [Source:NCBI gene... [more]
ENSORLT00000012942.21.571e-2247.17bromodomain-containing protein 4 [Source:NCBI gene... [more]
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BLAST of Bromodomain-containing protein 2 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5
Match NameE-valueIdentityDescription
SMESG000012934.10.000e+097.97SMESG000012934.1[more]
SMESG000075694.11.829e-5233.79SMESG000075694.1[more]
SMESG000005406.14.782e-4636.27SMESG000005406.1[more]
SMESG000040270.12.634e-4231.97SMESG000040270.1[more]
SMESG000080341.13.539e-2728.53SMESG000080341.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30013454 ID=SMED30013454|Name=Bromodomain-containing protein 2|organism=Schmidtea mediterranea sexual|type=transcript|length=2998bp
ACAAGTTTGTTGTTTCTTGAATTGAATGGAATATCCTTATACGAATCAGT
TATTGTATATTAAAAAAAATGTGATAAATGTGCTGTTGAGAAATTCTAAT
TCTGAATCTTTCAAAGTTCCAGTCAATCCTGAGTTGCTTGGTATTCCTAA
TTATCCGGACATTATAAAATATCCCATGGATTTTGGAACAATCAAAATAA
AACTGGATAAGCAAGTTTATCAATCCGCTAACGAATGCAAAAGTGATTTT
TTGAGCGTGTTTCGTAATTGTTACATTTTTAATGAACCTGGTTCATTGTA
TGTTGACATGGCTTTAAAATTAGAAAACTTGTTTAAAAGAAAAATGACAG
ATTTACCAGTTCCTGAACATTATGTTCAAGATTCTACATTTCACACTCCA
AAAAGTACGAAAGTTAAGAAAGGAAAATCAATTAAATTTCACACACCTAA
TGTGAAACCTAATAGATTAACCGGCAACACAATGAATTCAATTGCAAAGT
CTGACATATCAATTAACCAGAAGCGAGTTAGATCCGAATCTAACAATGGT
TATACGAAGGAGGAACCTTTATTTAAAAAGTCAAAATTAGAAATTGATAT
TAAAATATGCAAACATATCATATTGAATTTAGTTTCAAAAAAATATGGCG
ACCTAAACCGTTACTTTTTGGAGCCAGTTGATGTCGAGGGTCTAAAACTT
CATGATTATTTTGACATCGTTAAAAAACCAATGGATCTTGGAACAGTTAA
AAATAAATTATTTGATGGATTTTACCAAAGCAATGATGAATTTGCTGAAG
ATATTAAACTGATTTTTAAAAATTGTTATTTATACAATCCTGAAGGTCAC
GAAGTTAATAGATGCGGGAAATTGTTGGAAGATATTTTCAATAAATTATA
TCAGGGTGCTTTTGGAAATAGTAAAATTACATCAAAACCAACGAGAACAC
AGCATCGCAGCTACGATGATTTGCAGCCATTGTTACAAAAAATTCTTAAA
AGGCAAGCTGAAATTGATAACATGCACATGGATATAATAAAAAGAAATAT
AGAAATCCAGCAATCTATAGATTTTATAAATGGAACCGAACTTATTAAAT
CAATTAAAGCAAGTGTTAATATTAATTCGAAACAGTCGAATGCATCGTCA
AAGAGGGCCTTTTATAATACAACAAACGGTGATACAAAATTGGAGAAAAA
TTTTTCTCCTAAGCCAGACATTGTAAGACAAATTTCGAAGGTAGAACAGA
AAAGTGAATCATATATATCGAAATTATATATGAACAATCCAAATGTTCTC
AACAAACCCAGTGAAATTCAAAAATCACCCAAACCCGCTATTCCAAAACA
TGACCCACATAAAGAGGTTTCTAATCGACCAATTGAAGCGAAAAGAACCA
TTAAACCTACTTATAAATCGCAACCCAGTATAAATGACGAAATTTCTAAA
CCGATTGCAAAACGGCCATTAAATCATATCAGTAACCACGTATCAACCGA
CAACCACATTAGTTCCAATGATTTACCAAATCCGATAGAACCTCTCACTA
AACCAACTCCGGAAACATTTAAGCCAGATACTAAGAAACCAACAAAAAAC
GCAGAAGAATACAGTGTAAAACTGAAAGAAATCAAATCCTGGATCAGTTC
TTTATCGCCGGAAATGTCAATGAAAATCAGGGAGTTCATAAACAAATCAG
AAAATCGAAATGTCGTTTCGGTGAGTTTAATGAAACTGAAACCGTCGACA
ATTAACGGTCTTTATAAAATGATGACTGAGCCGATTAAGGAACCGGAAAA
AGTTGAATCGAAATCCGATTTGAAAGAATTCACTATTGAAGATCGAATGC
AACTCAGTCAGGATCTTCGACTGCTCGGAGATAAATGTTCAGAGAAAATT
CTCAACATCTATAAAAAGACCGAAGACGTACAGTCTTCAGATGGAGAGTG
TGAAATCGATTTTCAAACGATGAAATTGGTAACTTTGCACAGTTTGAGAG
AATTCGCTGATAAGTGTCTGCAAAAAAAACGTGAGAAACAACTGAAAAAA
TGTGCAGTGACAGCGGGTCAGCCAGTCGGGAATAATGGCGATATCAGCGA
TTCTGATTCATCAGATTCTTCAGATAGTGATGGATCAGATTCCAATTCGG
ATGCTTCCACATCGTCTTCTGACAATGAACTGTTCAATAATCTGTCTAAA
CCACAAATCCCTACCCAAATCCCTACTCAGACTCCCAGCAGCATTAGATC
AAACTTTACTCCGAAAATTCCCCCAGAAATCGTTTCCAAACCGTTAGTTG
ATCTTCAAACCGTCACCACAATATCAATACCTCAATTGAGCTCAAGTTCC
GAAAAGGTGAATATCGACAACACTCAGGAAGGAAGCCGTCTGAGTGATTC
ATCAGATTCTGATAAAGGAAAAGACGACGACGACGACGACGATGATGATG
ATGATGATGGAATCGCAGAAGATGAAATGGATGGAGATGACCTAAATGTC
ACGCTGGATGAAGAAATAATCCCCCTCTCAAAACCGATCAGTTTGCCTCC
AGTTCTCAATCGATTGAAATCTGTGGATTTGCTCTCTCCTCTCTGTCCTC
AAGATGGCAATGTTAATTTCTCGATGAATTTGTCCCCGCCGTCTTTATTT
ATGCAGCCAGAGTGTTGCGTTCAGGAAGAAGTGGTGGAGATCAGTTACGC
TTCCCGATCCGACAGTGATTCCTGATCGGACTCCGCCGAGTCGCGATTAA
TTCCGCATGTAAATATGAGCTCGCACACATACACACATACATACAAATAT
ATTGCTATTTATTAGTAGATTCCGTCATCACTGTACAGCAGTAGTCAGCG
CAATTAGAGGATTATCATTTACAGCAATCCCCTTCTGGCCCCATTGGCTG
AATTTAGTCACCTCCATTTGCCGCTGTCCTTTTCTTTTAGCATTGTGATC
TATCTTATTATTGTTATTATCATTTCCATTATTATTATTATTATTATT
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protein sequence of SMED30013454-orf-1

>SMED30013454-orf-1 ID=SMED30013454-orf-1|Name=SMED30013454-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=900bp
MEYPYTNQLLYIKKNVINVLLRNSNSESFKVPVNPELLGIPNYPDIIKYP
MDFGTIKIKLDKQVYQSANECKSDFLSVFRNCYIFNEPGSLYVDMALKLE
NLFKRKMTDLPVPEHYVQDSTFHTPKSTKVKKGKSIKFHTPNVKPNRLTG
NTMNSIAKSDISINQKRVRSESNNGYTKEEPLFKKSKLEIDIKICKHIIL
NLVSKKYGDLNRYFLEPVDVEGLKLHDYFDIVKKPMDLGTVKNKLFDGFY
QSNDEFAEDIKLIFKNCYLYNPEGHEVNRCGKLLEDIFNKLYQGAFGNSK
ITSKPTRTQHRSYDDLQPLLQKILKRQAEIDNMHMDIIKRNIEIQQSIDF
INGTELIKSIKASVNINSKQSNASSKRAFYNTTNGDTKLEKNFSPKPDIV
RQISKVEQKSESYISKLYMNNPNVLNKPSEIQKSPKPAIPKHDPHKEVSN
RPIEAKRTIKPTYKSQPSINDEISKPIAKRPLNHISNHVSTDNHISSNDL
PNPIEPLTKPTPETFKPDTKKPTKNAEEYSVKLKEIKSWISSLSPEMSMK
IREFINKSENRNVVSVSLMKLKPSTINGLYKMMTEPIKEPEKVESKSDLK
EFTIEDRMQLSQDLRLLGDKCSEKILNIYKKTEDVQSSDGECEIDFQTMK
LVTLHSLREFADKCLQKKREKQLKKCAVTAGQPVGNNGDISDSDSSDSSD
SDGSDSNSDASTSSSDNELFNNLSKPQIPTQIPTQTPSSIRSNFTPKIPP
EIVSKPLVDLQTVTTISIPQLSSSSEKVNIDNTQEGSRLSDSSDSDKGKD
DDDDDDDDDDDGIAEDEMDGDDLNVTLDEEIIPLSKPISLPPVLNRLKSV
DLLSPLCPQDGNVNFSMNLSPPSLFMQPECCVQEEVVEISYASRSDSDS*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: cellular component
TermDefinition
GO:0016020membrane
GO:0016021integral component of membrane
GO:0005634nucleus
GO:0005737cytoplasm
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000016pharynx
PLANA:0000034epidermis
PLANA:0000099neuron
PLANA:0002111X2 cell
PLANA:0003116parenchymal cell
Vocabulary: INTERPRO
TermDefinition
IPR001487Bromodomain
IPR027353NET_dom
IPR018359Bromodomain_CS
Vocabulary: molecular function
TermDefinition
GO:0005515protein binding
GO:0003682chromatin binding
GO:0070577lysine-acetylated histone binding
Vocabulary: biological process
TermDefinition
GO:0006334nucleosome assembly
GO:0006351transcription, DNA-templated
GO:0006355regulation of transcription, DNA-templated
GO:0006357regulation of transcription from RNA polymerase II promoter
GO:0016569covalent chromatin modification