Fibronectin type III and ankyrin repeat domains 1
|
Overview
Neoblast Clusters
Zeng et. al., 2018▻ Overview▻ Neoblast Population
Overview
Single cell RNA-seq of pluripotent neoblasts and its early progeniesWe isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)Explore this single cell expression dataset with our NB Cluster Shiny App
Neoblast Population
Embryonic Expression
Davies et. al., 2017
Hover the mouse over a column in the graph to view average RPKM values per sample. Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult. back to top Anatomical Expression
PAGE et. al., 2020SMED30013415 has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGEPAGE Curations: 3
Homology
BLAST of Fibronectin type III and ankyrin repeat domains 1 vs. Ensembl Human
Match: FANK1 (fibronectin type III and ankyrin repeat domains 1 [Source:HGNC Symbol;Acc:HGNC:23527]) HSP 1 Score: 110.153 bits (274), Expect = 3.083e-41 Identity = 62/199 (31.16%), Postives = 113/199 (56.78%), Query Frame = 3
Query: 51 IPPKIP-APAVEIVNHHMLSISWSDINKRLSLILSEEE-AKCLAEISFKKINNFDEPWIVKGYADSCELEDFDQDSVYNYRIRLRNKNGWGEYSDEKSVHFPKEPVTGDDLHRAIIMNDEQLLLKLLQSGKINMNIPDRYDYTPLMACAIRNLEGLFACLVEYKVELDVQNKAGKTALMLAANKGNSRMVQLLLNHGAN 641
+PP P P V V HH + + W D+ K+ +E+ + E K++ + I GYA +E + ++Y +R+++ + +G EYS SV +EP++ + LHRA+ +NDE LL+++LQ G++ +++P+++ +T LM A + L LV +++++N +GK +LMLA G+ +V+ L HGA+
Sbjct: 1 MPPSKPHPPVVGKVTHHSIELYW-DLEKKAKRQGPQEQWFRFSIEEEDPKMHTYG--IIYTGYATKHVVEGLEPRTLYRFRLKVTSPSGECEYSPLVSVSTTREPISSEHLHRAVSVNDEDLLVRILQGGRVKVDVPNKFGFTALMVAAQKGYTRLVKILVSNGTDVNLKNGSGKDSLMLACYAGHLDVVKYLRRHGAS 196 HSP 2 Score: 78.9518 bits (193), Expect = 3.083e-41 Identity = 39/126 (30.95%), Postives = 77/126 (61.11%), Query Frame = 2
Query: 653 GMSALFYGVDNENIIIVRMLLEAGCDVNDTDKENEWTPLIRLAVLANNGNSKLGILLLQHGANINKQDTFGNSALIHCAFHNSHQELTRVLLSHGANMHLKNKSGHNAYQISQSMNNTNITLVMEE 1030
G +AL + D + ++ +++ GC+V+ D + WTPL+R++ A +GN ++ LL+ GAN+N +D G + L+ A N+H+EL ++LL GA+ +KN+ G ++++ + ++ ++EE
Sbjct: 204 GCTALHWAADGGHCSVIEWMIKDGCEVDVVDTGSGWTPLMRVS--AVSGNQRVASLLIDAGANVNVKDRNGKTPLM-VAVLNNHEELVQLLLDKGADASVKNEFGKGVLEMARVFDRQSVVSLLEE 326
BLAST of Fibronectin type III and ankyrin repeat domains 1 vs. Ensembl Human
Match: FANK1 (fibronectin type III and ankyrin repeat domains 1 [Source:HGNC Symbol;Acc:HGNC:23527]) HSP 1 Score: 109.768 bits (273), Expect = 3.320e-41 Identity = 62/199 (31.16%), Postives = 113/199 (56.78%), Query Frame = 3
Query: 51 IPPKIP-APAVEIVNHHMLSISWSDINKRLSLILSEEE-AKCLAEISFKKINNFDEPWIVKGYADSCELEDFDQDSVYNYRIRLRNKNGWGEYSDEKSVHFPKEPVTGDDLHRAIIMNDEQLLLKLLQSGKINMNIPDRYDYTPLMACAIRNLEGLFACLVEYKVELDVQNKAGKTALMLAANKGNSRMVQLLLNHGAN 641
+PP P P V V HH + + W D+ K+ +E+ + E K++ + I GYA +E + ++Y +R+++ + +G EYS SV +EP++ + LHRA+ +NDE LL+++LQ G++ +++P+++ +T LM A + L LV +++++N +GK +LMLA G+ +V+ L HGA+
Sbjct: 7 MPPSKPHPPVVGKVTHHSIELYW-DLEKKAKRQGPQEQWFRFSIEEEDPKMHTYG--IIYTGYATKHVVEGLEPRTLYRFRLKVTSPSGECEYSPLVSVSTTREPISSEHLHRAVSVNDEDLLVRILQGGRVKVDVPNKFGFTALMVAAQKGYTRLVKILVSNGTDVNLKNGSGKDSLMLACYAGHLDVVKYLRRHGAS 202 HSP 2 Score: 78.9518 bits (193), Expect = 3.320e-41 Identity = 39/126 (30.95%), Postives = 77/126 (61.11%), Query Frame = 2
Query: 653 GMSALFYGVDNENIIIVRMLLEAGCDVNDTDKENEWTPLIRLAVLANNGNSKLGILLLQHGANINKQDTFGNSALIHCAFHNSHQELTRVLLSHGANMHLKNKSGHNAYQISQSMNNTNITLVMEE 1030
G +AL + D + ++ +++ GC+V+ D + WTPL+R++ A +GN ++ LL+ GAN+N +D G + L+ A N+H+EL ++LL GA+ +KN+ G ++++ + ++ ++EE
Sbjct: 210 GCTALHWAADGGHCSVIEWMIKDGCEVDVVDTGSGWTPLMRVS--AVSGNQRVASLLIDAGANVNVKDRNGKTPLM-VAVLNNHEELVQLLLDKGADASVKNEFGKGVLEMARVFDRQSVVSLLEE 332
BLAST of Fibronectin type III and ankyrin repeat domains 1 vs. Ensembl Human
Match: FANK1 (fibronectin type III and ankyrin repeat domains 1 [Source:HGNC Symbol;Acc:HGNC:23527]) HSP 1 Score: 80.1073 bits (196), Expect = 4.193e-25 Identity = 35/96 (36.46%), Postives = 64/96 (66.67%), Query Frame = 3
Query: 354 EPVTGDDLHRAIIMNDEQLLLKLLQSGKINMNIPDRYDYTPLMACAIRNLEGLFACLVEYKVELDVQNKAGKTALMLAANKGNSRMVQLLLNHGAN 641
EP++ + LHRA+ +NDE LL+++LQ G++ +++P+++ +T LM A + L LV +++++N +GK +LMLA G+ +V+ L HGA+
Sbjct: 2 EPISSEHLHRAVSVNDEDLLVRILQGGRVKVDVPNKFGFTALMVAAQKGYTRLVKILVSNGTDVNLKNGSGKDSLMLACYAGHLDVVKYLRRHGAS 97 HSP 2 Score: 54.6842 bits (130), Expect = 4.193e-25 Identity = 25/76 (32.89%), Postives = 47/76 (61.84%), Query Frame = 2
Query: 653 GMSALFYGVDNENIIIVRMLLEAGCDVNDTDKENEWTPLIRLAVLANNGNSKLGILLLQHGANINKQDTFGNSALI 880
G +AL + D + ++ +++ GC+V+ D + WTPL+R++ A +GN ++ LL+ GAN+N +D G + L+
Sbjct: 105 GCTALHWAADGGHCSVIEWMIKDGCEVDVVDTGSGWTPLMRVS--AVSGNQRVASLLIDAGANVNVKDRNGKTPLM 178
BLAST of Fibronectin type III and ankyrin repeat domains 1 vs. Ensembl Human
Match: FANK1 (fibronectin type III and ankyrin repeat domains 1 [Source:HGNC Symbol;Acc:HGNC:23527]) HSP 1 Score: 87.8113 bits (216), Expect = 4.060e-19 Identity = 57/214 (26.64%), Postives = 107/214 (50.00%), Query Frame = 3
Query: 51 IPPKIP-APAVEIVNHHMLSISWSDINKRLSLILSEEE-AKCLAEISFKKINNFDEPWIVKGYADSCELEDFDQDSVYNYRIRLRNKNGWGEYS------DEKSVHFPKEPVTGDDLHRAIIMNDEQLLLKLLQSGKINMNIPDRYDYTPLMACAIRNLEGL-FAC----------LVEYKVELDVQNKAGKTALMLAANKGNSRMVQLLLNHG 635
+PP P P V V HH + + W D+ K+ +E+ + E K++ + I GYA +E + ++Y +R+++ + +G EYS S+ EP++ + LHRA+ +NDE LL+++LQ G++ +++P+++ +T LM A + L AC L + ++ G TAL AA+ G+ +++ ++ G
Sbjct: 1 MPPSKPHPPVVGKVTHHSIELYW-DLEKKAKRQGPQEQWFRFSIEEEDPKMHTYGI--IYTGYATKHVVEGLEPRTLYRFRLKVTSPSGECEYSPLVSVSTTSSIWLGGEPISSEHLHRAVSVNDEDLLVRILQGGRVKVDVPNKFGFTALMVAAQKGYTSLMLACYAGHLDVVKYLRRHGASWQARDLGGCTALHWAADGGHCSVIEWMIKDG 211 HSP 2 Score: 55.4546 bits (132), Expect = 4.737e-8 Identity = 25/76 (32.89%), Postives = 47/76 (61.84%), Query Frame = 2
Query: 653 GMSALFYGVDNENIIIVRMLLEAGCDVNDTDKENEWTPLIRLAVLANNGNSKLGILLLQHGANINKQDTFGNSALI 880
G +AL + D + ++ +++ GC+V+ D + WTPL+R++ A +GN ++ LL+ GAN+N +D G + L+
Sbjct: 188 GCTALHWAADGGHCSVIEWMIKDGCEVDVVDTGSGWTPLMRVS--AVSGNQRVASLLIDAGANVNVKDRNGKTPLM 261
BLAST of Fibronectin type III and ankyrin repeat domains 1 vs. Ensembl Human
Match: ANK2 (ankyrin 2 [Source:HGNC Symbol;Acc:HGNC:493]) HSP 1 Score: 51.9878 bits (123), Expect = 2.256e-15 Identity = 34/115 (29.57%), Postives = 57/115 (49.57%), Query Frame = 2
Query: 653 GMSALFYGVDNENIIIVRMLLEAGCDVNDTDKENEWTPLIRLAVLANNGNSKLGILLLQHGANINKQDTFGNSALIHCAFHNSHQELTRVLLSHGANMHLKNKSGHNAYQISQSM 997
G+++L + + + +L + G D D + +TPLI V + GN K+ LL+ GAN+N + G + L H A H + VLL HGA + +G+ A I++ +
Sbjct: 674 GLTSLHLAAQEDKVNVADILTKHGAD-QDAHTKLGYTPLI---VACHYGNVKMVNFLLKQGANVNAKTKNGYTPL-HQAAQQGHTHIINVLLQHGAKPNATTANGNTALAIAKRL 783 HSP 2 Score: 50.0618 bits (118), Expect = 2.256e-15 Identity = 31/89 (34.83%), Postives = 51/89 (57.30%), Query Frame = 3
Query: 375 LHRAIIMNDEQLLLKLLQSGKINMNIPDRYDYTPLMACAIRNLEGLFACLVEYKVELDVQNKAGKTALMLAANKGNSRMVQLLLNHGAN 641
LH A +++++ L LL+ G + + + YTPL A +N + + L+ Y E ++ K G T L LA+ +G++ MV LLL+ GAN
Sbjct: 579 LHVAAHYDNQKVALLLLEKGA-SPHATAKNGYTPLHIAAKKNQMQIASTLLNYGAETNIVTKQGVTPLHLASQEGHTDMVTLLLDKGAN 666 HSP 3 Score: 41.9726 bits (97), Expect = 2.540e-7 Identity = 30/125 (24.00%), Postives = 59/125 (47.20%), Query Frame = 2
Query: 650 KGMSALFYGVDNENIIIVRMLLEAGCDVNDTDKENEWTPLIRLAVLANNGNSKLGILLLQHGANINKQDTFGNSALIHCAFHNSHQELTRVLLSHGANMHLKNKSGHNAYQISQSMNNTNITLVM 1024
+G++ L + +V +LL+ G +++ + K L L + A + +L +HGA+ + G + LI A H + ++ LL GAN++ K K+G+ + +T+I V+
Sbjct: 640 QGVTPLHLASQEGHTDMVTLLLDKGANIHMSTKSG----LTSLHLAAQEDKVNVADILTKHGADQDAHTKLGYTPLI-VACHYGNVKMVNFLLKQGANVNAKTKNGYTPLHQAAQQGHTHIINVL 759 HSP 4 Score: 32.3426 bits (72), Expect = 2.540e-7 Identity = 22/75 (29.33%), Postives = 38/75 (50.67%), Query Frame = 3
Query: 420 LLQSGKINMNIPDRYDYTPLMACAIRNLEGLFACLVEYKVELDVQNKAGKTALMLAANKGNSRMVQLLLNHGANP 644
LL++G + ++ + +TPL A + L++ + D K G T L +AA+ N ++ LLL GA+P
Sbjct: 528 LLEAGAAH-SLATKKGFTPLHVAAKYGSLDVAKLLLQRRAAADSAGKNGLTPLHVAAHYDNQKVALLLLEKGASP 601 HSP 5 Score: 50.8322 bits (120), Expect = 3.842e-6 Identity = 34/124 (27.42%), Postives = 58/124 (46.77%), Query Frame = 2
Query: 653 GMSALFYGVDNENIIIVRMLLEAGCDVNDTDKENEWTPLIRLAVLANNGNSKLGILLLQHGANINKQDTFGNSALIHCAFHNSHQELTRVLLSHGANMHLKNKSGHNAYQISQSMNNTNITLVM 1024
G++ L +N + +LLE G + T K N +TPL + A ++ LL +GA N G + L H A H ++ +LL GAN+H+ KSG + ++ + N+ ++
Sbjct: 575 GLTPLHVAAHYDNQKVALLLLEKGASPHATAK-NGYTPL---HIAAKKNQMQIASTLLNYGAETNIVTKQGVTPL-HLASQEGHTDMVTLLLDKGANIHMSTKSGLTSLHLAAQEDKVNVADIL 693
BLAST of Fibronectin type III and ankyrin repeat domains 1 vs. Ensembl Celegans
Match: unc-44 (AO49 ankyrin [Source:UniProtKB/TrEMBL;Acc:Q7JP86]) HSP 1 Score: 50.8322 bits (120), Expect = 1.147e-12 Identity = 38/127 (29.92%), Postives = 64/127 (50.39%), Query Frame = 2
Query: 650 KGMSALFYGVDNENIIIVRMLLEAGCDVNDTDKENEWTPLIRLAVLANNGNSKLGILLLQHGANINKQDTFGNSALIHCAFHNSHQELTRVLLSHGANMHLKNKSGHNAYQISQSMNNTNITLVMEE 1030
KG + L N+ +VR+LLE G V D + +N+ TP L V A+ N K+ +LLL++GA+ G + L H A + E+ LL A+ + K+++G +S + I+ ++ E
Sbjct: 556 KGFTPLHLASKYGNLEVVRLLLERGTPV-DIEGKNQVTP---LHVAAHYNNDKVAMLLLENGASAKAAAKNGYTPL-HIAAKKNQMEIASTLLQFKADPNAKSRAGFTPLHLSAQEGHKEISGLLIE 677 HSP 2 Score: 40.4318 bits (93), Expect = 1.147e-12 Identity = 29/89 (32.58%), Postives = 44/89 (49.44%), Query Frame = 3
Query: 375 LHRAIIMNDEQLLLKLLQSGKINMNIPDRYDYTPLMACAIRNLEGLFACLVEYKVELDVQNKAGKTALMLAANKGNSRMVQLLLNHGAN 641
LH A M +++ LLQ G N ++ TPL A N + L+ ++D Q + +T L +A+ GN+ +V LLL GAN
Sbjct: 429 LHVAAFMGAINIVIYLLQQGA-NPDVETVRGETPLHLAARANQTDVVRVLIRNGAKVDAQARELQTPLHIASRLGNTDIVILLLQAGAN 516 HSP 3 Score: 50.447 bits (119), Expect = 7.293e-11 Identity = 38/138 (27.54%), Postives = 62/138 (44.93%), Query Frame = 2
Query: 650 KGMSALFYGVDNENIIIVRMLLEAGCDVNDTDKENEWTPLIRLAVLANNGNSKLGILLLQHGANINKQDTFGNSALIHCAFHNSHQELTRVLLSHGANMHLKNKSGHNAYQISQSMNNTNITLVMEEFLNPSHCSNEN 1063
+G + L +VR+L+ G V+ +E + TPL + + GN+ + ILLLQ GAN N T N + +H A +E+ +LL H A+ L K G ++ N + ++ E P +N
Sbjct: 457 RGETPLHLAARANQTDVVRVLIRNGAKVDAQARELQ-TPL---HIASRLGNTDIVILLLQAGANSNAT-TRDNYSPLHIAAKEGQEEVAGILLDHNADKTLLTKKGFTPLHLASKYGNLEVVRLLLERGTPVDIEGKN 589 HSP 4 Score: 35.039 bits (79), Expect = 7.293e-11 Identity = 19/59 (32.20%), Postives = 31/59 (52.54%), Query Frame = 3
Query: 468 YTPLMACAIRNLEGLFACLVEYKVELDVQNKAGKTALMLAANKGNSRMVQLLLNHGANP 644
+TPL +N + L++Y+ ++ ++G T L +AA G +V LL GANP
Sbjct: 393 FTPLHIACKKNRIKVVELLLKYRAAIEATTESGLTPLHVAAFMGAINIVIYLLQQGANP 451 HSP 5 Score: 36.965 bits (84), Expect = 1.002e-6 Identity = 28/116 (24.14%), Postives = 52/116 (44.83%), Query Frame = 2
Query: 749 ENEWTPLIRLAVL---ANNGNSKLGILLLQHGANINKQDTFGNSALIHCAFHNSHQELTRVLLSHGANMHLKNKSGHNAYQISQSMNNTNITLVM-----------EEFLNPSHCS 1054
EN+ +RL L A ++ LLLQ+ N + G + L H A H H+ + ++LL GAN++ + + + ++ TN+ ++ ++ L P HC+
Sbjct: 186 ENDSKGKVRLPALHIAAKKDDTTAATLLLQNEHNPDVTSKSGFTPL-HIAAHYGHENVGQLLLEKGANVNYQARHNISPLHVATKWGRTNMANLLLSRGAIIDSRTKDLLTPLHCA 300 HSP 6 Score: 33.8834 bits (76), Expect = 1.002e-6 Identity = 20/77 (25.97%), Postives = 39/77 (50.65%), Query Frame = 3
Query: 402 EQLLLKLLQSGKINMNIPDRYDYTPLMACAIRNLEGLFACLVEYKVELDVQNKAGKTALMLAANKGNSRMVQLLLNH 632
+ L++ +L N+N+ +TPL A N E + L+++ + + G T L +A +G+ R+V +LL +
Sbjct: 111 QSLIVTILVENGANVNVQSVNGFTPLYMAAQENHEEVVKYLLKHGANQALSTEDGFTPLAVALQQGHDRVVAVLLEN 187 HSP 7 Score: 43.5134 bits (101), Expect = 8.173e-6 Identity = 34/126 (26.98%), Postives = 58/126 (46.03%), Query Frame = 2
Query: 647 FKGMSALFYGVDNENIIIVRMLLEAGCDVNDTDKENEWTPLIRLAVLANNGNSKLGILLLQHGANINKQDTFGNSALIHCAFHNSHQELTRVLLSHGANMHLKNKSGHNAYQISQSMNNTNITLVM 1024
G + L I +V +LL+ + T E+ TPL V A G + I LLQ GAN + + G + L H A + ++ RVL+ +GA + + + I+ + NT+I +++
Sbjct: 390 LNGFTPLHIACKKNRIKVVELLLKYRAAIEAT-TESGLTPL---HVAAFMGAINIVIYLLQQGANPDVETVRGETPL-HLAARANQTDVVRVLIRNGAKVDAQARELQTPLHIASRLGNTDIVILL 510 HSP 8 Score: 24.6386 bits (52), Expect = 8.173e-6 Identity = 11/25 (44.00%), Postives = 18/25 (72.00%), Query Frame = 3
Query: 570 TALMLAANKGNSRMVQLLLNHGANP 644
T L +AA+ G+ R+ +LLL+ A+P
Sbjct: 361 TPLHVAAHCGHVRVAKLLLDRSADP 385
BLAST of Fibronectin type III and ankyrin repeat domains 1 vs. Ensembl Celegans
Match: unc-44 (AO49 ankyrin [Source:UniProtKB/TrEMBL;Acc:Q7JP86]) HSP 1 Score: 50.8322 bits (120), Expect = 1.147e-12 Identity = 38/127 (29.92%), Postives = 64/127 (50.39%), Query Frame = 2
Query: 650 KGMSALFYGVDNENIIIVRMLLEAGCDVNDTDKENEWTPLIRLAVLANNGNSKLGILLLQHGANINKQDTFGNSALIHCAFHNSHQELTRVLLSHGANMHLKNKSGHNAYQISQSMNNTNITLVMEE 1030
KG + L N+ +VR+LLE G V D + +N+ TP L V A+ N K+ +LLL++GA+ G + L H A + E+ LL A+ + K+++G +S + I+ ++ E
Sbjct: 556 KGFTPLHLASKYGNLEVVRLLLERGTPV-DIEGKNQVTP---LHVAAHYNNDKVAMLLLENGASAKAAAKNGYTPL-HIAAKKNQMEIASTLLQFKADPNAKSRAGFTPLHLSAQEGHKEISGLLIE 677 HSP 2 Score: 40.4318 bits (93), Expect = 1.147e-12 Identity = 29/89 (32.58%), Postives = 44/89 (49.44%), Query Frame = 3
Query: 375 LHRAIIMNDEQLLLKLLQSGKINMNIPDRYDYTPLMACAIRNLEGLFACLVEYKVELDVQNKAGKTALMLAANKGNSRMVQLLLNHGAN 641
LH A M +++ LLQ G N ++ TPL A N + L+ ++D Q + +T L +A+ GN+ +V LLL GAN
Sbjct: 429 LHVAAFMGAINIVIYLLQQGA-NPDVETVRGETPLHLAARANQTDVVRVLIRNGAKVDAQARELQTPLHIASRLGNTDIVILLLQAGAN 516 HSP 3 Score: 50.447 bits (119), Expect = 7.293e-11 Identity = 38/138 (27.54%), Postives = 62/138 (44.93%), Query Frame = 2
Query: 650 KGMSALFYGVDNENIIIVRMLLEAGCDVNDTDKENEWTPLIRLAVLANNGNSKLGILLLQHGANINKQDTFGNSALIHCAFHNSHQELTRVLLSHGANMHLKNKSGHNAYQISQSMNNTNITLVMEEFLNPSHCSNEN 1063
+G + L +VR+L+ G V+ +E + TPL + + GN+ + ILLLQ GAN N T N + +H A +E+ +LL H A+ L K G ++ N + ++ E P +N
Sbjct: 457 RGETPLHLAARANQTDVVRVLIRNGAKVDAQARELQ-TPL---HIASRLGNTDIVILLLQAGANSNAT-TRDNYSPLHIAAKEGQEEVAGILLDHNADKTLLTKKGFTPLHLASKYGNLEVVRLLLERGTPVDIEGKN 589 HSP 4 Score: 35.039 bits (79), Expect = 7.293e-11 Identity = 19/59 (32.20%), Postives = 31/59 (52.54%), Query Frame = 3
Query: 468 YTPLMACAIRNLEGLFACLVEYKVELDVQNKAGKTALMLAANKGNSRMVQLLLNHGANP 644
+TPL +N + L++Y+ ++ ++G T L +AA G +V LL GANP
Sbjct: 393 FTPLHIACKKNRIKVVELLLKYRAAIEATTESGLTPLHVAAFMGAINIVIYLLQQGANP 451 HSP 5 Score: 36.965 bits (84), Expect = 1.002e-6 Identity = 28/116 (24.14%), Postives = 52/116 (44.83%), Query Frame = 2
Query: 749 ENEWTPLIRLAVL---ANNGNSKLGILLLQHGANINKQDTFGNSALIHCAFHNSHQELTRVLLSHGANMHLKNKSGHNAYQISQSMNNTNITLVM-----------EEFLNPSHCS 1054
EN+ +RL L A ++ LLLQ+ N + G + L H A H H+ + ++LL GAN++ + + + ++ TN+ ++ ++ L P HC+
Sbjct: 186 ENDSKGKVRLPALHIAAKKDDTTAATLLLQNEHNPDVTSKSGFTPL-HIAAHYGHENVGQLLLEKGANVNYQARHNISPLHVATKWGRTNMANLLLSRGAIIDSRTKDLLTPLHCA 300 HSP 6 Score: 33.8834 bits (76), Expect = 1.002e-6 Identity = 20/77 (25.97%), Postives = 39/77 (50.65%), Query Frame = 3
Query: 402 EQLLLKLLQSGKINMNIPDRYDYTPLMACAIRNLEGLFACLVEYKVELDVQNKAGKTALMLAANKGNSRMVQLLLNH 632
+ L++ +L N+N+ +TPL A N E + L+++ + + G T L +A +G+ R+V +LL +
Sbjct: 111 QSLIVTILVENGANVNVQSVNGFTPLYMAAQENHEEVVKYLLKHGANQALSTEDGFTPLAVALQQGHDRVVAVLLEN 187 HSP 7 Score: 43.5134 bits (101), Expect = 8.173e-6 Identity = 34/126 (26.98%), Postives = 58/126 (46.03%), Query Frame = 2
Query: 647 FKGMSALFYGVDNENIIIVRMLLEAGCDVNDTDKENEWTPLIRLAVLANNGNSKLGILLLQHGANINKQDTFGNSALIHCAFHNSHQELTRVLLSHGANMHLKNKSGHNAYQISQSMNNTNITLVM 1024
G + L I +V +LL+ + T E+ TPL V A G + I LLQ GAN + + G + L H A + ++ RVL+ +GA + + + I+ + NT+I +++
Sbjct: 390 LNGFTPLHIACKKNRIKVVELLLKYRAAIEAT-TESGLTPL---HVAAFMGAINIVIYLLQQGANPDVETVRGETPL-HLAARANQTDVVRVLIRNGAKVDAQARELQTPLHIASRLGNTDIVILL 510 HSP 8 Score: 24.6386 bits (52), Expect = 8.173e-6 Identity = 11/25 (44.00%), Postives = 18/25 (72.00%), Query Frame = 3
Query: 570 TALMLAANKGNSRMVQLLLNHGANP 644
T L +AA+ G+ R+ +LLL+ A+P
Sbjct: 361 TPLHVAAHCGHVRVAKLLLDRSADP 385
BLAST of Fibronectin type III and ankyrin repeat domains 1 vs. Ensembl Celegans
Match: unc-44 (AO49 ankyrin [Source:UniProtKB/TrEMBL;Acc:Q7JP86]) HSP 1 Score: 49.2914 bits (116), Expect = 1.871e-12 Identity = 38/127 (29.92%), Postives = 64/127 (50.39%), Query Frame = 2
Query: 650 KGMSALFYGVDNENIIIVRMLLEAGCDVNDTDKENEWTPLIRLAVLANNGNSKLGILLLQHGANINKQDTFGNSALIHCAFHNSHQELTRVLLSHGANMHLKNKSGHNAYQISQSMNNTNITLVMEE 1030
KG + L N+ +VR+LLE G V D + +N+ TP L V A+ N K+ +LLL++GA+ G + L H A + E+ LL A+ + K+++G +S + I+ ++ E
Sbjct: 556 KGFTPLHLASKYGNLEVVRLLLERGTPV-DIEGKNQVTP---LHVAAHYNNDKVAMLLLENGASAKAAAKNGYTPL-HIAAKKNQMEIASTLLQFKADPNAKSRAGFTPLHLSAQEGHKEISGLLIE 677 HSP 2 Score: 41.2022 bits (95), Expect = 1.871e-12 Identity = 29/89 (32.58%), Postives = 44/89 (49.44%), Query Frame = 3
Query: 375 LHRAIIMNDEQLLLKLLQSGKINMNIPDRYDYTPLMACAIRNLEGLFACLVEYKVELDVQNKAGKTALMLAANKGNSRMVQLLLNHGAN 641
LH A M +++ LLQ G N ++ TPL A N + L+ ++D Q + +T L +A+ GN+ +V LLL GAN
Sbjct: 429 LHVAAFMGAINIVIYLLQQGA-NPDVETVRGETPLHLAARANQTDVVRVLIRNGAKVDAQARELQTPLHIASRLGNTDIVILLLQAGAN 516 HSP 3 Score: 48.9062 bits (115), Expect = 1.336e-10 Identity = 38/138 (27.54%), Postives = 62/138 (44.93%), Query Frame = 2
Query: 650 KGMSALFYGVDNENIIIVRMLLEAGCDVNDTDKENEWTPLIRLAVLANNGNSKLGILLLQHGANINKQDTFGNSALIHCAFHNSHQELTRVLLSHGANMHLKNKSGHNAYQISQSMNNTNITLVMEEFLNPSHCSNEN 1063
+G + L +VR+L+ G V+ +E + TPL + + GN+ + ILLLQ GAN N T N + +H A +E+ +LL H A+ L K G ++ N + ++ E P +N
Sbjct: 457 RGETPLHLAARANQTDVVRVLIRNGAKVDAQARELQ-TPL---HIASRLGNTDIVILLLQAGANSNAT-TRDNYSPLHIAAKEGQEEVAGILLDHNADKTLLTKKGFTPLHLASKYGNLEVVRLLLERGTPVDIEGKN 589 HSP 4 Score: 35.4242 bits (80), Expect = 1.336e-10 Identity = 19/59 (32.20%), Postives = 31/59 (52.54%), Query Frame = 3
Query: 468 YTPLMACAIRNLEGLFACLVEYKVELDVQNKAGKTALMLAANKGNSRMVQLLLNHGANP 644
+TPL +N + L++Y+ ++ ++G T L +AA G +V LL GANP
Sbjct: 393 FTPLHIACKKNRIKVVELLLKYRAAIEATTESGLTPLHVAAFMGAINIVIYLLQQGANP 451 HSP 5 Score: 35.8094 bits (81), Expect = 1.666e-6 Identity = 28/116 (24.14%), Postives = 52/116 (44.83%), Query Frame = 2
Query: 749 ENEWTPLIRLAVL---ANNGNSKLGILLLQHGANINKQDTFGNSALIHCAFHNSHQELTRVLLSHGANMHLKNKSGHNAYQISQSMNNTNITLVM-----------EEFLNPSHCS 1054
EN+ +RL L A ++ LLLQ+ N + G + L H A H H+ + ++LL GAN++ + + + ++ TN+ ++ ++ L P HC+
Sbjct: 186 ENDSKGKVRLPALHIAAKKDDTTAATLLLQNEHNPDVTSKSGFTPL-HIAAHYGHENVGQLLLEKGANVNYQARHNISPLHVATKWGRTNMANLLLSRGAIIDSRTKDLLTPLHCA 300 HSP 6 Score: 34.6538 bits (78), Expect = 1.666e-6 Identity = 20/77 (25.97%), Postives = 39/77 (50.65%), Query Frame = 3
Query: 402 EQLLLKLLQSGKINMNIPDRYDYTPLMACAIRNLEGLFACLVEYKVELDVQNKAGKTALMLAANKGNSRMVQLLLNH 632
+ L++ +L N+N+ +TPL A N E + L+++ + + G T L +A +G+ R+V +LL +
Sbjct: 111 QSLIVTILVENGANVNVQSVNGFTPLYMAAQENHEEVVKYLLKHGANQALSTEDGFTPLAVALQQGHDRVVAVLLEN 187
BLAST of Fibronectin type III and ankyrin repeat domains 1 vs. Ensembl Celegans
Match: unc-44 (AO49 ankyrin [Source:UniProtKB/TrEMBL;Acc:Q7JP86]) HSP 1 Score: 49.2914 bits (116), Expect = 1.871e-12 Identity = 38/127 (29.92%), Postives = 64/127 (50.39%), Query Frame = 2
Query: 650 KGMSALFYGVDNENIIIVRMLLEAGCDVNDTDKENEWTPLIRLAVLANNGNSKLGILLLQHGANINKQDTFGNSALIHCAFHNSHQELTRVLLSHGANMHLKNKSGHNAYQISQSMNNTNITLVMEE 1030
KG + L N+ +VR+LLE G V D + +N+ TP L V A+ N K+ +LLL++GA+ G + L H A + E+ LL A+ + K+++G +S + I+ ++ E
Sbjct: 556 KGFTPLHLASKYGNLEVVRLLLERGTPV-DIEGKNQVTP---LHVAAHYNNDKVAMLLLENGASAKAAAKNGYTPL-HIAAKKNQMEIASTLLQFKADPNAKSRAGFTPLHLSAQEGHKEISGLLIE 677 HSP 2 Score: 41.2022 bits (95), Expect = 1.871e-12 Identity = 29/89 (32.58%), Postives = 44/89 (49.44%), Query Frame = 3
Query: 375 LHRAIIMNDEQLLLKLLQSGKINMNIPDRYDYTPLMACAIRNLEGLFACLVEYKVELDVQNKAGKTALMLAANKGNSRMVQLLLNHGAN 641
LH A M +++ LLQ G N ++ TPL A N + L+ ++D Q + +T L +A+ GN+ +V LLL GAN
Sbjct: 429 LHVAAFMGAINIVIYLLQQGA-NPDVETVRGETPLHLAARANQTDVVRVLIRNGAKVDAQARELQTPLHIASRLGNTDIVILLLQAGAN 516 HSP 3 Score: 48.9062 bits (115), Expect = 1.336e-10 Identity = 38/138 (27.54%), Postives = 62/138 (44.93%), Query Frame = 2
Query: 650 KGMSALFYGVDNENIIIVRMLLEAGCDVNDTDKENEWTPLIRLAVLANNGNSKLGILLLQHGANINKQDTFGNSALIHCAFHNSHQELTRVLLSHGANMHLKNKSGHNAYQISQSMNNTNITLVMEEFLNPSHCSNEN 1063
+G + L +VR+L+ G V+ +E + TPL + + GN+ + ILLLQ GAN N T N + +H A +E+ +LL H A+ L K G ++ N + ++ E P +N
Sbjct: 457 RGETPLHLAARANQTDVVRVLIRNGAKVDAQARELQ-TPL---HIASRLGNTDIVILLLQAGANSNAT-TRDNYSPLHIAAKEGQEEVAGILLDHNADKTLLTKKGFTPLHLASKYGNLEVVRLLLERGTPVDIEGKN 589 HSP 4 Score: 35.4242 bits (80), Expect = 1.336e-10 Identity = 19/59 (32.20%), Postives = 31/59 (52.54%), Query Frame = 3
Query: 468 YTPLMACAIRNLEGLFACLVEYKVELDVQNKAGKTALMLAANKGNSRMVQLLLNHGANP 644
+TPL +N + L++Y+ ++ ++G T L +AA G +V LL GANP
Sbjct: 393 FTPLHIACKKNRIKVVELLLKYRAAIEATTESGLTPLHVAAFMGAINIVIYLLQQGANP 451 HSP 5 Score: 35.8094 bits (81), Expect = 1.666e-6 Identity = 28/116 (24.14%), Postives = 52/116 (44.83%), Query Frame = 2
Query: 749 ENEWTPLIRLAVL---ANNGNSKLGILLLQHGANINKQDTFGNSALIHCAFHNSHQELTRVLLSHGANMHLKNKSGHNAYQISQSMNNTNITLVM-----------EEFLNPSHCS 1054
EN+ +RL L A ++ LLLQ+ N + G + L H A H H+ + ++LL GAN++ + + + ++ TN+ ++ ++ L P HC+
Sbjct: 186 ENDSKGKVRLPALHIAAKKDDTTAATLLLQNEHNPDVTSKSGFTPL-HIAAHYGHENVGQLLLEKGANVNYQARHNISPLHVATKWGRTNMANLLLSRGAIIDSRTKDLLTPLHCA 300 HSP 6 Score: 34.6538 bits (78), Expect = 1.666e-6 Identity = 20/77 (25.97%), Postives = 39/77 (50.65%), Query Frame = 3
Query: 402 EQLLLKLLQSGKINMNIPDRYDYTPLMACAIRNLEGLFACLVEYKVELDVQNKAGKTALMLAANKGNSRMVQLLLNH 632
+ L++ +L N+N+ +TPL A N E + L+++ + + G T L +A +G+ R+V +LL +
Sbjct: 111 QSLIVTILVENGANVNVQSVNGFTPLYMAAQENHEEVVKYLLKHGANQALSTEDGFTPLAVALQQGHDRVVAVLLEN 187
BLAST of Fibronectin type III and ankyrin repeat domains 1 vs. Ensembl Celegans
Match: unc-44 (AO49 ankyrin [Source:UniProtKB/TrEMBL;Acc:Q7JP86]) HSP 1 Score: 49.2914 bits (116), Expect = 1.872e-12 Identity = 38/127 (29.92%), Postives = 64/127 (50.39%), Query Frame = 2
Query: 650 KGMSALFYGVDNENIIIVRMLLEAGCDVNDTDKENEWTPLIRLAVLANNGNSKLGILLLQHGANINKQDTFGNSALIHCAFHNSHQELTRVLLSHGANMHLKNKSGHNAYQISQSMNNTNITLVMEE 1030
KG + L N+ +VR+LLE G V D + +N+ TP L V A+ N K+ +LLL++GA+ G + L H A + E+ LL A+ + K+++G +S + I+ ++ E
Sbjct: 556 KGFTPLHLASKYGNLEVVRLLLERGTPV-DIEGKNQVTP---LHVAAHYNNDKVAMLLLENGASAKAAAKNGYTPL-HIAAKKNQMEIASTLLQFKADPNAKSRAGFTPLHLSAQEGHKEISGLLIE 677 HSP 2 Score: 41.2022 bits (95), Expect = 1.872e-12 Identity = 29/89 (32.58%), Postives = 44/89 (49.44%), Query Frame = 3
Query: 375 LHRAIIMNDEQLLLKLLQSGKINMNIPDRYDYTPLMACAIRNLEGLFACLVEYKVELDVQNKAGKTALMLAANKGNSRMVQLLLNHGAN 641
LH A M +++ LLQ G N ++ TPL A N + L+ ++D Q + +T L +A+ GN+ +V LLL GAN
Sbjct: 429 LHVAAFMGAINIVIYLLQQGA-NPDVETVRGETPLHLAARANQTDVVRVLIRNGAKVDAQARELQTPLHIASRLGNTDIVILLLQAGAN 516 HSP 3 Score: 48.9062 bits (115), Expect = 1.315e-10 Identity = 38/138 (27.54%), Postives = 62/138 (44.93%), Query Frame = 2
Query: 650 KGMSALFYGVDNENIIIVRMLLEAGCDVNDTDKENEWTPLIRLAVLANNGNSKLGILLLQHGANINKQDTFGNSALIHCAFHNSHQELTRVLLSHGANMHLKNKSGHNAYQISQSMNNTNITLVMEEFLNPSHCSNEN 1063
+G + L +VR+L+ G V+ +E + TPL + + GN+ + ILLLQ GAN N T N + +H A +E+ +LL H A+ L K G ++ N + ++ E P +N
Sbjct: 457 RGETPLHLAARANQTDVVRVLIRNGAKVDAQARELQ-TPL---HIASRLGNTDIVILLLQAGANSNAT-TRDNYSPLHIAAKEGQEEVAGILLDHNADKTLLTKKGFTPLHLASKYGNLEVVRLLLERGTPVDIEGKN 589 HSP 4 Score: 35.4242 bits (80), Expect = 1.315e-10 Identity = 19/59 (32.20%), Postives = 31/59 (52.54%), Query Frame = 3
Query: 468 YTPLMACAIRNLEGLFACLVEYKVELDVQNKAGKTALMLAANKGNSRMVQLLLNHGANP 644
+TPL +N + L++Y+ ++ ++G T L +AA G +V LL GANP
Sbjct: 393 FTPLHIACKKNRIKVVELLLKYRAAIEATTESGLTPLHVAAFMGAINIVIYLLQQGANP 451 HSP 5 Score: 35.8094 bits (81), Expect = 1.614e-6 Identity = 28/116 (24.14%), Postives = 52/116 (44.83%), Query Frame = 2
Query: 749 ENEWTPLIRLAVL---ANNGNSKLGILLLQHGANINKQDTFGNSALIHCAFHNSHQELTRVLLSHGANMHLKNKSGHNAYQISQSMNNTNITLVM-----------EEFLNPSHCS 1054
EN+ +RL L A ++ LLLQ+ N + G + L H A H H+ + ++LL GAN++ + + + ++ TN+ ++ ++ L P HC+
Sbjct: 186 ENDSKGKVRLPALHIAAKKDDTTAATLLLQNEHNPDVTSKSGFTPL-HIAAHYGHENVGQLLLEKGANVNYQARHNISPLHVATKWGRTNMANLLLSRGAIIDSRTKDLLTPLHCA 300 HSP 6 Score: 34.6538 bits (78), Expect = 1.614e-6 Identity = 20/77 (25.97%), Postives = 39/77 (50.65%), Query Frame = 3
Query: 402 EQLLLKLLQSGKINMNIPDRYDYTPLMACAIRNLEGLFACLVEYKVELDVQNKAGKTALMLAANKGNSRMVQLLLNH 632
+ L++ +L N+N+ +TPL A N E + L+++ + + G T L +A +G+ R+V +LL +
Sbjct: 111 QSLIVTILVENGANVNVQSVNGFTPLYMAAQENHEEVVKYLLKHGANQALSTEDGFTPLAVALQQGHDRVVAVLLEN 187
BLAST of Fibronectin type III and ankyrin repeat domains 1 vs. Ensembl Fly
Match: Ank2 (gene:FBgn0261788 transcript:FBtr0344222) HSP 1 Score: 45.8246 bits (107), Expect = 1.814e-11 Identity = 28/88 (31.82%), Postives = 49/88 (55.68%), Query Frame = 3
Query: 375 LHRAIIMNDEQLLLKLLQSGKINMNIPDRYDYTPLMACAIRNLEGLFACLVEYKVELDVQNKAGKTALMLAANKGNSRMVQLLLNHGA 638
LH A N++Q+ L LL+ G + + + +TPL A +N + L+EY + ++KAG T L L++ +G++ + LL+ H A
Sbjct: 572 LHVACHYNNQQVALLLLEKGA-SPHATAKNGHTPLHIAARKNQMDIATTLLEYGALANAESKAGFTPLHLSSQEGHAEISNLLIEHKA 658 HSP 2 Score: 41.9726 bits (97), Expect = 1.814e-11 Identity = 27/115 (23.48%), Postives = 56/115 (48.70%), Query Frame = 2
Query: 653 GMSALFYGVDNENIIIVRMLLEAGCDVNDTDKENEWTPLIRLAVLANNGNSKLGILLLQHGANINKQDTFGNSALIHCAFHNSHQELTRVLLSHGANMHLKNKSGHNAYQISQSM 997
G++ + +N+ + +L + G +++ K +TPL V ++ G + + LLQ+GAN++ + G + L H H + +LL H AN + + +G I++ +
Sbjct: 667 GLTPMHLCAQEDNVNVAEILEKNGANIDMATKAG-YTPL---HVASHFGQANMVRFLLQNGANVDAATSIGYTPL-HQTAQQGHCHIVNLLLEHKANANAQTVNGQTPLHIARKL 776 HSP 3 Score: 36.965 bits (84), Expect = 5.072e-7 Identity = 28/120 (23.33%), Postives = 53/120 (44.17%), Query Frame = 2
Query: 653 GMSALFYGVDNENIIIVRMLLEAGCDVNDTDKENEWTPLIRLAVLANNGNSKLGILLLQHGANINKQDTFGNSALIHCAFHNSHQELTRVLLSHGANMHLKNKSGHNAYQISQSMNNTNI 1012
G + L + I LLE G N K +TPL + + G++++ LL++H A +N G + + CA + + +L +GAN+ + K+G+ ++ N+
Sbjct: 601 GHTPLHIAARKNQMDIATTLLEYGALANAESKAG-FTPL---HLSSQEGHAEISNLLIEHKAAVNHPAKNGLTPMHLCA-QEDNVNVAEILEKNGANIDMATKAGYTPLHVASHFGQANM 715 HSP 4 Score: 35.8094 bits (81), Expect = 5.072e-7 Identity = 24/90 (26.67%), Postives = 45/90 (50.00%), Query Frame = 3
Query: 375 LHRAIIMNDEQLLLKLLQSGKINMNIPDRYDYTPLMACAIRNLEGLFACLVEYKVELDVQNKAGKTALMLAANKGNSRMVQLLLNHGANP 644
LH A +++ L+++G ++ + +TPL A + L++ + ++D Q K G T L +A + N ++ LLL GA+P
Sbjct: 506 LHIAAKEGQDEVAAVLIENGAA-LDAATKKGFTPLHLTAKYGHIKVAQLLLQKEADVDAQGKNGVTPLHVACHYNNQQVALLLLEKGASP 594 HSP 5 Score: 43.1282 bits (100), Expect = 5.677e-7 Identity = 32/125 (25.60%), Postives = 56/125 (44.80%), Query Frame = 2
Query: 650 KGMSALFYGVDNENIIIVRMLLEAGCDVNDTDKENEWTPLIRLAVLANNGNSKLGILLLQHGANINKQDTFGNSALIHCAFHNSHQELTRVLLSHGANMHLKNKSGHNAYQISQSMNNTNITLVM 1024
+G + L I+R+LL G V+ +E + TPL + + GN + +LLLQHGA ++ +AL H A E+ VL+ +GA + K G ++ + + ++
Sbjct: 435 RGETPLHLAARANQTDIIRILLRNGAQVDARAREQQ-TPL---HIASRLGNVDIVMLLLQHGAQVDATTKDMYTAL-HIAAKEGQDEVAAVLIENGAALDAATKKGFTPLHLTAKYGHIKVAQLL 554 HSP 6 Score: 29.261 bits (64), Expect = 5.677e-7 Identity = 17/59 (28.81%), Postives = 28/59 (47.46%), Query Frame = 3
Query: 468 YTPLMACAIRNLEGLFACLVEYKVELDVQNKAGKTALMLAANKGNSRMVQLLLNHGANP 644
+TPL +N + L+ + + ++G T L +AA G +V LL H A+P
Sbjct: 371 FTPLHIACKKNRLKVVELLLRHGASISATTESGLTPLHVAAFMGCMNIVIYLLQHDASP 429 HSP 7 Score: 48.9062 bits (115), Expect = 6.784e-6 Identity = 36/102 (35.29%), Postives = 54/102 (52.94%), Query Frame = 2
Query: 662 ALFYGVDNENIIIVRMLLEAGCDVNDTDKENEWTPLIRLAVLANNGNSKLGILLLQHGANINKQDTFGNSALIHCAFHNSHQELTRVLLSHGANMHLKNKSG 967
A YG N+NI +L++ G DVN + K N + L V A G + + LLL+ G NI + G + L HCA + H+++ +LL GA + K K+G
Sbjct: 212 ASHYG--NQNI--ANLLIQKGADVNYSAKHN----ISPLHVAAKWGKTNMVSLLLEKGGNIEAKTRDGLTPL-HCAARSGHEQVVDMLLERGAPISAKTKNG 304 HSP 8 Score: 48.521 bits (114), Expect = 9.519e-6 Identity = 37/126 (29.37%), Postives = 61/126 (48.41%), Query Frame = 2
Query: 653 GMSALFYGVDNENIIIVRMLLEAGCDVNDTDKENEWTPLIRLAVLANNGNSKLGILLLQHGANINKQDTFGNSALIHCAFHNSHQELTRVLLSHGANMHLKNKSGHNAYQISQSMNNTNITLVMEE 1030
G++AL + +I +V LL G V+ K+ + +A LA G ++ LLL+H A++N Q G + L A N H + R+LLS+GAN L + G ++ + + V+ E
Sbjct: 44 GLNALHLASKDGHIHVVSELLRRGAIVDSATKKG--NTALHIASLA--GQEEVVKLLLEHNASVNVQSQNGFTPLYMAAQEN-HDAVVRLLLSNGANQSLATEDGFTPLAVAMQQGHDKVVAVLLE 164
BLAST of Fibronectin type III and ankyrin repeat domains 1 vs. Ensembl Fly
Match: Ank2 (gene:FBgn0261788 transcript:FBtr0303121) HSP 1 Score: 44.2838 bits (103), Expect = 3.938e-11 Identity = 28/88 (31.82%), Postives = 49/88 (55.68%), Query Frame = 3
Query: 375 LHRAIIMNDEQLLLKLLQSGKINMNIPDRYDYTPLMACAIRNLEGLFACLVEYKVELDVQNKAGKTALMLAANKGNSRMVQLLLNHGA 638
LH A N++Q+ L LL+ G + + + +TPL A +N + L+EY + ++KAG T L L++ +G++ + LL+ H A
Sbjct: 572 LHVACHYNNQQVALLLLEKGA-SPHATAKNGHTPLHIAARKNQMDIATTLLEYGALANAESKAGFTPLHLSSQEGHAEISNLLIEHKA 658 HSP 2 Score: 42.3578 bits (98), Expect = 3.938e-11 Identity = 27/115 (23.48%), Postives = 56/115 (48.70%), Query Frame = 2
Query: 653 GMSALFYGVDNENIIIVRMLLEAGCDVNDTDKENEWTPLIRLAVLANNGNSKLGILLLQHGANINKQDTFGNSALIHCAFHNSHQELTRVLLSHGANMHLKNKSGHNAYQISQSM 997
G++ + +N+ + +L + G +++ K +TPL V ++ G + + LLQ+GAN++ + G + L H H + +LL H AN + + +G I++ +
Sbjct: 667 GLTPMHLCAQEDNVNVAEILEKNGANIDMATKAG-YTPL---HVASHFGQANMVRFLLQNGANVDAATSIGYTPL-HQTAQQGHCHIVNLLLEHKANANAQTVNGQTPLHIARKL 776 HSP 3 Score: 43.1282 bits (100), Expect = 3.376e-9 Identity = 32/126 (25.40%), Postives = 57/126 (45.24%), Query Frame = 2
Query: 653 GMSALFYGVDNENIIIVRMLLEAGCDVNDTDKENEWTPLIRLAVLANNGNSKLGILLLQHGANINKQDTFGNSALIHCAFHNSHQELTRVLLSHGANMHLKNKSGHNAYQISQSMNNTNITLVMEE 1030
G++ L N + +LLE G + T K N TPL + A + LL++GA N + G + L H + H E++ +L+ H A ++ K+G + +N N+ ++E+
Sbjct: 568 GVTPLHVACHYNNQQVALLLLEKGASPHATAK-NGHTPL---HIAARKNQMDIATTLLEYGALANAESKAGFTPL-HLSSQEGHAEISNLLIEHKAAVNHPAKNGLTPMHLCAQEDNVNVAEILEK 688 HSP 4 Score: 36.965 bits (84), Expect = 3.376e-9 Identity = 29/90 (32.22%), Postives = 44/90 (48.89%), Query Frame = 3
Query: 375 LHRAIIMNDEQLLLKLLQSG-KINMNIPDRYDYTPLMACAIRNLEGLFACLVEYKVELDVQNKAGKTALMLAANKGNSRMVQLLLNHGAN 641
LH A + + +++ LLQ G +++ D Y T L A + + A L+E LD K G T L L A G+ ++ QLLL A+
Sbjct: 473 LHIASRLGNVDIVMLLLQHGAQVDATTKDMY--TALHIAAKEGQDEVAAVLIENGAALDAATKKGFTPLHLTAKYGHIKVAQLLLQKEAD 560 HSP 5 Score: 43.5134 bits (101), Expect = 4.143e-7 Identity = 32/125 (25.60%), Postives = 56/125 (44.80%), Query Frame = 2
Query: 650 KGMSALFYGVDNENIIIVRMLLEAGCDVNDTDKENEWTPLIRLAVLANNGNSKLGILLLQHGANINKQDTFGNSALIHCAFHNSHQELTRVLLSHGANMHLKNKSGHNAYQISQSMNNTNITLVM 1024
+G + L I+R+LL G V+ +E + TPL + + GN + +LLLQHGA ++ +AL H A E+ VL+ +GA + K G ++ + + ++
Sbjct: 435 RGETPLHLAARANQTDIIRILLRNGAQVDARAREQQ-TPL---HIASRLGNVDIVMLLLQHGAQVDATTKDMYTAL-HIAAKEGQDEVAAVLIENGAALDAATKKGFTPLHLTAKYGHIKVAQLL 554 HSP 6 Score: 29.261 bits (64), Expect = 4.143e-7 Identity = 21/76 (27.63%), Postives = 33/76 (43.42%), Query Frame = 3
Query: 417 KLLQSGKINMNIPDRYDYTPLMACAIRNLEGLFACLVEYKVELDVQNKAGKTALMLAANKGNSRMVQLLLNHGANP 644
KLL + N +TPL +N + L+ + + ++G T L +AA G +V LL H A+P
Sbjct: 354 KLLLDRNADANARALNGFTPLHIACKKNRLKVVELLLRHGASISATTESGLTPLHVAAFMGCMNIVIYLLQHDASP 429 HSP 7 Score: 37.3502 bits (85), Expect = 9.874e-7 Identity = 28/120 (23.33%), Postives = 53/120 (44.17%), Query Frame = 2
Query: 653 GMSALFYGVDNENIIIVRMLLEAGCDVNDTDKENEWTPLIRLAVLANNGNSKLGILLLQHGANINKQDTFGNSALIHCAFHNSHQELTRVLLSHGANMHLKNKSGHNAYQISQSMNNTNI 1012
G + L + I LLE G N K +TPL + + G++++ LL++H A +N G + + CA + + +L +GAN+ + K+G+ ++ N+
Sbjct: 601 GHTPLHIAARKNQMDIATTLLEYGALANAESKAG-FTPL---HLSSQEGHAEISNLLIEHKAAVNHPAKNGLTPMHLCA-QEDNVNVAEILEKNGANIDMATKAGYTPLHVASHFGQANM 715 HSP 8 Score: 34.2686 bits (77), Expect = 9.874e-7 Identity = 24/90 (26.67%), Postives = 45/90 (50.00%), Query Frame = 3
Query: 375 LHRAIIMNDEQLLLKLLQSGKINMNIPDRYDYTPLMACAIRNLEGLFACLVEYKVELDVQNKAGKTALMLAANKGNSRMVQLLLNHGANP 644
LH A +++ L+++G ++ + +TPL A + L++ + ++D Q K G T L +A + N ++ LLL GA+P
Sbjct: 506 LHIAAKEGQDEVAAVLIENGAA-LDAATKKGFTPLHLTAKYGHIKVAQLLLQKEADVDAQGKNGVTPLHVACHYNNQQVALLLLEKGASP 594 HSP 9 Score: 49.2914 bits (116), Expect = 5.140e-6 Identity = 36/102 (35.29%), Postives = 54/102 (52.94%), Query Frame = 2
Query: 662 ALFYGVDNENIIIVRMLLEAGCDVNDTDKENEWTPLIRLAVLANNGNSKLGILLLQHGANINKQDTFGNSALIHCAFHNSHQELTRVLLSHGANMHLKNKSG 967
A YG N+NI +L++ G DVN + K N + L V A G + + LLL+ G NI + G + L HCA + H+++ +LL GA + K K+G
Sbjct: 212 ASHYG--NQNI--ANLLIQKGADVNYSAKHN----ISPLHVAAKWGKTNMVSLLLEKGGNIEAKTRDGLTPL-HCAARSGHEQVVDMLLERGAPISAKTKNG 304 HSP 10 Score: 48.9062 bits (115), Expect = 7.026e-6 Identity = 37/126 (29.37%), Postives = 61/126 (48.41%), Query Frame = 2
Query: 653 GMSALFYGVDNENIIIVRMLLEAGCDVNDTDKENEWTPLIRLAVLANNGNSKLGILLLQHGANINKQDTFGNSALIHCAFHNSHQELTRVLLSHGANMHLKNKSGHNAYQISQSMNNTNITLVMEE 1030
G++AL + +I +V LL G V+ K+ + +A LA G ++ LLL+H A++N Q G + L A N H + R+LLS+GAN L + G ++ + + V+ E
Sbjct: 44 GLNALHLASKDGHIHVVSELLRRGAIVDSATKKG--NTALHIASLA--GQEEVVKLLLEHNASVNVQSQNGFTPLYMAAQEN-HDAVVRLLLSNGANQSLATEDGFTPLAVAMQQGHDKVVAVLLE 164
BLAST of Fibronectin type III and ankyrin repeat domains 1 vs. Ensembl Fly
Match: Ank2 (gene:FBgn0261788 transcript:FBtr0303117) HSP 1 Score: 44.2838 bits (103), Expect = 4.102e-11 Identity = 28/88 (31.82%), Postives = 49/88 (55.68%), Query Frame = 3
Query: 375 LHRAIIMNDEQLLLKLLQSGKINMNIPDRYDYTPLMACAIRNLEGLFACLVEYKVELDVQNKAGKTALMLAANKGNSRMVQLLLNHGA 638
LH A N++Q+ L LL+ G + + + +TPL A +N + L+EY + ++KAG T L L++ +G++ + LL+ H A
Sbjct: 572 LHVACHYNNQQVALLLLEKGA-SPHATAKNGHTPLHIAARKNQMDIATTLLEYGALANAESKAGFTPLHLSSQEGHAEISNLLIEHKA 658 HSP 2 Score: 42.3578 bits (98), Expect = 4.102e-11 Identity = 27/115 (23.48%), Postives = 56/115 (48.70%), Query Frame = 2
Query: 653 GMSALFYGVDNENIIIVRMLLEAGCDVNDTDKENEWTPLIRLAVLANNGNSKLGILLLQHGANINKQDTFGNSALIHCAFHNSHQELTRVLLSHGANMHLKNKSGHNAYQISQSM 997
G++ + +N+ + +L + G +++ K +TPL V ++ G + + LLQ+GAN++ + G + L H H + +LL H AN + + +G I++ +
Sbjct: 667 GLTPMHLCAQEDNVNVAEILEKNGANIDMATKAG-YTPL---HVASHFGQANMVRFLLQNGANVDAATSIGYTPL-HQTAQQGHCHIVNLLLEHKANANAQTVNGQTPLHIARKL 776 HSP 3 Score: 42.743 bits (99), Expect = 3.602e-9 Identity = 32/126 (25.40%), Postives = 57/126 (45.24%), Query Frame = 2
Query: 653 GMSALFYGVDNENIIIVRMLLEAGCDVNDTDKENEWTPLIRLAVLANNGNSKLGILLLQHGANINKQDTFGNSALIHCAFHNSHQELTRVLLSHGANMHLKNKSGHNAYQISQSMNNTNITLVMEE 1030
G++ L N + +LLE G + T K N TPL + A + LL++GA N + G + L H + H E++ +L+ H A ++ K+G + +N N+ ++E+
Sbjct: 568 GVTPLHVACHYNNQQVALLLLEKGASPHATAK-NGHTPL---HIAARKNQMDIATTLLEYGALANAESKAGFTPL-HLSSQEGHAEISNLLIEHKAAVNHPAKNGLTPMHLCAQEDNVNVAEILEK 688 HSP 4 Score: 36.965 bits (84), Expect = 3.602e-9 Identity = 29/90 (32.22%), Postives = 44/90 (48.89%), Query Frame = 3
Query: 375 LHRAIIMNDEQLLLKLLQSG-KINMNIPDRYDYTPLMACAIRNLEGLFACLVEYKVELDVQNKAGKTALMLAANKGNSRMVQLLLNHGAN 641
LH A + + +++ LLQ G +++ D Y T L A + + A L+E LD K G T L L A G+ ++ QLLL A+
Sbjct: 473 LHIASRLGNVDIVMLLLQHGAQVDATTKDMY--TALHIAAKEGQDEVAAVLIENGAALDAATKKGFTPLHLTAKYGHIKVAQLLLQKEAD 560 HSP 5 Score: 43.5134 bits (101), Expect = 4.211e-7 Identity = 32/125 (25.60%), Postives = 56/125 (44.80%), Query Frame = 2
Query: 650 KGMSALFYGVDNENIIIVRMLLEAGCDVNDTDKENEWTPLIRLAVLANNGNSKLGILLLQHGANINKQDTFGNSALIHCAFHNSHQELTRVLLSHGANMHLKNKSGHNAYQISQSMNNTNITLVM 1024
+G + L I+R+LL G V+ +E + TPL + + GN + +LLLQHGA ++ +AL H A E+ VL+ +GA + K G ++ + + ++
Sbjct: 435 RGETPLHLAARANQTDIIRILLRNGAQVDARAREQQ-TPL---HIASRLGNVDIVMLLLQHGAQVDATTKDMYTAL-HIAAKEGQDEVAAVLIENGAALDAATKKGFTPLHLTAKYGHIKVAQLL 554 HSP 6 Score: 29.261 bits (64), Expect = 4.211e-7 Identity = 21/76 (27.63%), Postives = 33/76 (43.42%), Query Frame = 3
Query: 417 KLLQSGKINMNIPDRYDYTPLMACAIRNLEGLFACLVEYKVELDVQNKAGKTALMLAANKGNSRMVQLLLNHGANP 644
KLL + N +TPL +N + L+ + + ++G T L +AA G +V LL H A+P
Sbjct: 354 KLLLDRNADANARALNGFTPLHIACKKNRLKVVELLLRHGASISATTESGLTPLHVAAFMGCMNIVIYLLQHDASP 429 HSP 7 Score: 37.3502 bits (85), Expect = 1.020e-6 Identity = 28/120 (23.33%), Postives = 53/120 (44.17%), Query Frame = 2
Query: 653 GMSALFYGVDNENIIIVRMLLEAGCDVNDTDKENEWTPLIRLAVLANNGNSKLGILLLQHGANINKQDTFGNSALIHCAFHNSHQELTRVLLSHGANMHLKNKSGHNAYQISQSMNNTNI 1012
G + L + I LLE G N K +TPL + + G++++ LL++H A +N G + + CA + + +L +GAN+ + K+G+ ++ N+
Sbjct: 601 GHTPLHIAARKNQMDIATTLLEYGALANAESKAG-FTPL---HLSSQEGHAEISNLLIEHKAAVNHPAKNGLTPMHLCA-QEDNVNVAEILEKNGANIDMATKAGYTPLHVASHFGQANM 715 HSP 8 Score: 34.2686 bits (77), Expect = 1.020e-6 Identity = 24/90 (26.67%), Postives = 45/90 (50.00%), Query Frame = 3
Query: 375 LHRAIIMNDEQLLLKLLQSGKINMNIPDRYDYTPLMACAIRNLEGLFACLVEYKVELDVQNKAGKTALMLAANKGNSRMVQLLLNHGANP 644
LH A +++ L+++G ++ + +TPL A + L++ + ++D Q K G T L +A + N ++ LLL GA+P
Sbjct: 506 LHIAAKEGQDEVAAVLIENGAA-LDAATKKGFTPLHLTAKYGHIKVAQLLLQKEADVDAQGKNGVTPLHVACHYNNQQVALLLLEKGASP 594 HSP 9 Score: 49.2914 bits (116), Expect = 5.228e-6 Identity = 36/102 (35.29%), Postives = 54/102 (52.94%), Query Frame = 2
Query: 662 ALFYGVDNENIIIVRMLLEAGCDVNDTDKENEWTPLIRLAVLANNGNSKLGILLLQHGANINKQDTFGNSALIHCAFHNSHQELTRVLLSHGANMHLKNKSG 967
A YG N+NI +L++ G DVN + K N + L V A G + + LLL+ G NI + G + L HCA + H+++ +LL GA + K K+G
Sbjct: 212 ASHYG--NQNI--ANLLIQKGADVNYSAKHN----ISPLHVAAKWGKTNMVSLLLEKGGNIEAKTRDGLTPL-HCAARSGHEQVVDMLLERGAPISAKTKNG 304 HSP 10 Score: 48.9062 bits (115), Expect = 7.209e-6 Identity = 37/126 (29.37%), Postives = 61/126 (48.41%), Query Frame = 2
Query: 653 GMSALFYGVDNENIIIVRMLLEAGCDVNDTDKENEWTPLIRLAVLANNGNSKLGILLLQHGANINKQDTFGNSALIHCAFHNSHQELTRVLLSHGANMHLKNKSGHNAYQISQSMNNTNITLVMEE 1030
G++AL + +I +V LL G V+ K+ + +A LA G ++ LLL+H A++N Q G + L A N H + R+LLS+GAN L + G ++ + + V+ E
Sbjct: 44 GLNALHLASKDGHIHVVSELLRRGAIVDSATKKG--NTALHIASLA--GQEEVVKLLLEHNASVNVQSQNGFTPLYMAAQEN-HDAVVRLLLSNGANQSLATEDGFTPLAVAMQQGHDKVVAVLLE 164
BLAST of Fibronectin type III and ankyrin repeat domains 1 vs. Ensembl Fly
Match: Ank2 (gene:FBgn0261788 transcript:FBtr0303123) HSP 1 Score: 44.2838 bits (103), Expect = 4.167e-11 Identity = 28/88 (31.82%), Postives = 49/88 (55.68%), Query Frame = 3
Query: 375 LHRAIIMNDEQLLLKLLQSGKINMNIPDRYDYTPLMACAIRNLEGLFACLVEYKVELDVQNKAGKTALMLAANKGNSRMVQLLLNHGA 638
LH A N++Q+ L LL+ G + + + +TPL A +N + L+EY + ++KAG T L L++ +G++ + LL+ H A
Sbjct: 572 LHVACHYNNQQVALLLLEKGA-SPHATAKNGHTPLHIAARKNQMDIATTLLEYGALANAESKAGFTPLHLSSQEGHAEISNLLIEHKA 658 HSP 2 Score: 42.3578 bits (98), Expect = 4.167e-11 Identity = 27/115 (23.48%), Postives = 56/115 (48.70%), Query Frame = 2
Query: 653 GMSALFYGVDNENIIIVRMLLEAGCDVNDTDKENEWTPLIRLAVLANNGNSKLGILLLQHGANINKQDTFGNSALIHCAFHNSHQELTRVLLSHGANMHLKNKSGHNAYQISQSM 997
G++ + +N+ + +L + G +++ K +TPL V ++ G + + LLQ+GAN++ + G + L H H + +LL H AN + + +G I++ +
Sbjct: 667 GLTPMHLCAQEDNVNVAEILEKNGANIDMATKAG-YTPL---HVASHFGQANMVRFLLQNGANVDAATSIGYTPL-HQTAQQGHCHIVNLLLEHKANANAQTVNGQTPLHIARKL 776 HSP 3 Score: 43.1282 bits (100), Expect = 3.688e-9 Identity = 32/126 (25.40%), Postives = 57/126 (45.24%), Query Frame = 2
Query: 653 GMSALFYGVDNENIIIVRMLLEAGCDVNDTDKENEWTPLIRLAVLANNGNSKLGILLLQHGANINKQDTFGNSALIHCAFHNSHQELTRVLLSHGANMHLKNKSGHNAYQISQSMNNTNITLVMEE 1030
G++ L N + +LLE G + T K N TPL + A + LL++GA N + G + L H + H E++ +L+ H A ++ K+G + +N N+ ++E+
Sbjct: 568 GVTPLHVACHYNNQQVALLLLEKGASPHATAK-NGHTPL---HIAARKNQMDIATTLLEYGALANAESKAGFTPL-HLSSQEGHAEISNLLIEHKAAVNHPAKNGLTPMHLCAQEDNVNVAEILEK 688 HSP 4 Score: 36.965 bits (84), Expect = 3.688e-9 Identity = 29/90 (32.22%), Postives = 44/90 (48.89%), Query Frame = 3
Query: 375 LHRAIIMNDEQLLLKLLQSG-KINMNIPDRYDYTPLMACAIRNLEGLFACLVEYKVELDVQNKAGKTALMLAANKGNSRMVQLLLNHGAN 641
LH A + + +++ LLQ G +++ D Y T L A + + A L+E LD K G T L L A G+ ++ QLLL A+
Sbjct: 473 LHIASRLGNVDIVMLLLQHGAQVDATTKDMY--TALHIAAKEGQDEVAAVLIENGAALDAATKKGFTPLHLTAKYGHIKVAQLLLQKEAD 560 HSP 5 Score: 43.5134 bits (101), Expect = 4.310e-7 Identity = 32/125 (25.60%), Postives = 56/125 (44.80%), Query Frame = 2
Query: 650 KGMSALFYGVDNENIIIVRMLLEAGCDVNDTDKENEWTPLIRLAVLANNGNSKLGILLLQHGANINKQDTFGNSALIHCAFHNSHQELTRVLLSHGANMHLKNKSGHNAYQISQSMNNTNITLVM 1024
+G + L I+R+LL G V+ +E + TPL + + GN + +LLLQHGA ++ +AL H A E+ VL+ +GA + K G ++ + + ++
Sbjct: 435 RGETPLHLAARANQTDIIRILLRNGAQVDARAREQQ-TPL---HIASRLGNVDIVMLLLQHGAQVDATTKDMYTAL-HIAAKEGQDEVAAVLIENGAALDAATKKGFTPLHLTAKYGHIKVAQLL 554 HSP 6 Score: 29.261 bits (64), Expect = 4.310e-7 Identity = 21/76 (27.63%), Postives = 33/76 (43.42%), Query Frame = 3
Query: 417 KLLQSGKINMNIPDRYDYTPLMACAIRNLEGLFACLVEYKVELDVQNKAGKTALMLAANKGNSRMVQLLLNHGANP 644
KLL + N +TPL +N + L+ + + ++G T L +AA G +V LL H A+P
Sbjct: 354 KLLLDRNADANARALNGFTPLHIACKKNRLKVVELLLRHGASISATTESGLTPLHVAAFMGCMNIVIYLLQHDASP 429 HSP 7 Score: 37.3502 bits (85), Expect = 1.011e-6 Identity = 28/120 (23.33%), Postives = 53/120 (44.17%), Query Frame = 2
Query: 653 GMSALFYGVDNENIIIVRMLLEAGCDVNDTDKENEWTPLIRLAVLANNGNSKLGILLLQHGANINKQDTFGNSALIHCAFHNSHQELTRVLLSHGANMHLKNKSGHNAYQISQSMNNTNI 1012
G + L + I LLE G N K +TPL + + G++++ LL++H A +N G + + CA + + +L +GAN+ + K+G+ ++ N+
Sbjct: 601 GHTPLHIAARKNQMDIATTLLEYGALANAESKAG-FTPL---HLSSQEGHAEISNLLIEHKAAVNHPAKNGLTPMHLCA-QEDNVNVAEILEKNGANIDMATKAGYTPLHVASHFGQANM 715 HSP 8 Score: 34.2686 bits (77), Expect = 1.011e-6 Identity = 24/90 (26.67%), Postives = 45/90 (50.00%), Query Frame = 3
Query: 375 LHRAIIMNDEQLLLKLLQSGKINMNIPDRYDYTPLMACAIRNLEGLFACLVEYKVELDVQNKAGKTALMLAANKGNSRMVQLLLNHGANP 644
LH A +++ L+++G ++ + +TPL A + L++ + ++D Q K G T L +A + N ++ LLL GA+P
Sbjct: 506 LHIAAKEGQDEVAAVLIENGAA-LDAATKKGFTPLHLTAKYGHIKVAQLLLQKEADVDAQGKNGVTPLHVACHYNNQQVALLLLEKGASP 594 HSP 9 Score: 49.2914 bits (116), Expect = 5.012e-6 Identity = 36/102 (35.29%), Postives = 54/102 (52.94%), Query Frame = 2
Query: 662 ALFYGVDNENIIIVRMLLEAGCDVNDTDKENEWTPLIRLAVLANNGNSKLGILLLQHGANINKQDTFGNSALIHCAFHNSHQELTRVLLSHGANMHLKNKSG 967
A YG N+NI +L++ G DVN + K N + L V A G + + LLL+ G NI + G + L HCA + H+++ +LL GA + K K+G
Sbjct: 212 ASHYG--NQNI--ANLLIQKGADVNYSAKHN----ISPLHVAAKWGKTNMVSLLLEKGGNIEAKTRDGLTPL-HCAARSGHEQVVDMLLERGAPISAKTKNG 304 HSP 10 Score: 48.9062 bits (115), Expect = 7.092e-6 Identity = 37/126 (29.37%), Postives = 61/126 (48.41%), Query Frame = 2
Query: 653 GMSALFYGVDNENIIIVRMLLEAGCDVNDTDKENEWTPLIRLAVLANNGNSKLGILLLQHGANINKQDTFGNSALIHCAFHNSHQELTRVLLSHGANMHLKNKSGHNAYQISQSMNNTNITLVMEE 1030
G++AL + +I +V LL G V+ K+ + +A LA G ++ LLL+H A++N Q G + L A N H + R+LLS+GAN L + G ++ + + V+ E
Sbjct: 44 GLNALHLASKDGHIHVVSELLRRGAIVDSATKKG--NTALHIASLA--GQEEVVKLLLEHNASVNVQSQNGFTPLYMAAQEN-HDAVVRLLLSNGANQSLATEDGFTPLAVAMQQGHDKVVAVLLE 164
BLAST of Fibronectin type III and ankyrin repeat domains 1 vs. Ensembl Fly
Match: Ank2 (gene:FBgn0261788 transcript:FBtr0303114) HSP 1 Score: 44.2838 bits (103), Expect = 4.234e-11 Identity = 28/88 (31.82%), Postives = 49/88 (55.68%), Query Frame = 3
Query: 375 LHRAIIMNDEQLLLKLLQSGKINMNIPDRYDYTPLMACAIRNLEGLFACLVEYKVELDVQNKAGKTALMLAANKGNSRMVQLLLNHGA 638
LH A N++Q+ L LL+ G + + + +TPL A +N + L+EY + ++KAG T L L++ +G++ + LL+ H A
Sbjct: 572 LHVACHYNNQQVALLLLEKGA-SPHATAKNGHTPLHIAARKNQMDIATTLLEYGALANAESKAGFTPLHLSSQEGHAEISNLLIEHKA 658 HSP 2 Score: 42.3578 bits (98), Expect = 4.234e-11 Identity = 27/115 (23.48%), Postives = 56/115 (48.70%), Query Frame = 2
Query: 653 GMSALFYGVDNENIIIVRMLLEAGCDVNDTDKENEWTPLIRLAVLANNGNSKLGILLLQHGANINKQDTFGNSALIHCAFHNSHQELTRVLLSHGANMHLKNKSGHNAYQISQSM 997
G++ + +N+ + +L + G +++ K +TPL V ++ G + + LLQ+GAN++ + G + L H H + +LL H AN + + +G I++ +
Sbjct: 667 GLTPMHLCAQEDNVNVAEILEKNGANIDMATKAG-YTPL---HVASHFGQANMVRFLLQNGANVDAATSIGYTPL-HQTAQQGHCHIVNLLLEHKANANAQTVNGQTPLHIARKL 776 HSP 3 Score: 42.743 bits (99), Expect = 3.777e-9 Identity = 32/126 (25.40%), Postives = 57/126 (45.24%), Query Frame = 2
Query: 653 GMSALFYGVDNENIIIVRMLLEAGCDVNDTDKENEWTPLIRLAVLANNGNSKLGILLLQHGANINKQDTFGNSALIHCAFHNSHQELTRVLLSHGANMHLKNKSGHNAYQISQSMNNTNITLVMEE 1030
G++ L N + +LLE G + T K N TPL + A + LL++GA N + G + L H + H E++ +L+ H A ++ K+G + +N N+ ++E+
Sbjct: 568 GVTPLHVACHYNNQQVALLLLEKGASPHATAK-NGHTPL---HIAARKNQMDIATTLLEYGALANAESKAGFTPL-HLSSQEGHAEISNLLIEHKAAVNHPAKNGLTPMHLCAQEDNVNVAEILEK 688 HSP 4 Score: 36.965 bits (84), Expect = 3.777e-9 Identity = 29/90 (32.22%), Postives = 44/90 (48.89%), Query Frame = 3
Query: 375 LHRAIIMNDEQLLLKLLQSG-KINMNIPDRYDYTPLMACAIRNLEGLFACLVEYKVELDVQNKAGKTALMLAANKGNSRMVQLLLNHGAN 641
LH A + + +++ LLQ G +++ D Y T L A + + A L+E LD K G T L L A G+ ++ QLLL A+
Sbjct: 473 LHIASRLGNVDIVMLLLQHGAQVDATTKDMY--TALHIAAKEGQDEVAAVLIENGAALDAATKKGFTPLHLTAKYGHIKVAQLLLQKEAD 560 HSP 5 Score: 43.5134 bits (101), Expect = 4.485e-7 Identity = 32/125 (25.60%), Postives = 56/125 (44.80%), Query Frame = 2
Query: 650 KGMSALFYGVDNENIIIVRMLLEAGCDVNDTDKENEWTPLIRLAVLANNGNSKLGILLLQHGANINKQDTFGNSALIHCAFHNSHQELTRVLLSHGANMHLKNKSGHNAYQISQSMNNTNITLVM 1024
+G + L I+R+LL G V+ +E + TPL + + GN + +LLLQHGA ++ +AL H A E+ VL+ +GA + K G ++ + + ++
Sbjct: 435 RGETPLHLAARANQTDIIRILLRNGAQVDARAREQQ-TPL---HIASRLGNVDIVMLLLQHGAQVDATTKDMYTAL-HIAAKEGQDEVAAVLIENGAALDAATKKGFTPLHLTAKYGHIKVAQLL 554 HSP 6 Score: 29.261 bits (64), Expect = 4.485e-7 Identity = 21/76 (27.63%), Postives = 33/76 (43.42%), Query Frame = 3
Query: 417 KLLQSGKINMNIPDRYDYTPLMACAIRNLEGLFACLVEYKVELDVQNKAGKTALMLAANKGNSRMVQLLLNHGANP 644
KLL + N +TPL +N + L+ + + ++G T L +AA G +V LL H A+P
Sbjct: 354 KLLLDRNADANARALNGFTPLHIACKKNRLKVVELLLRHGASISATTESGLTPLHVAAFMGCMNIVIYLLQHDASP 429 HSP 7 Score: 37.3502 bits (85), Expect = 1.069e-6 Identity = 28/120 (23.33%), Postives = 53/120 (44.17%), Query Frame = 2
Query: 653 GMSALFYGVDNENIIIVRMLLEAGCDVNDTDKENEWTPLIRLAVLANNGNSKLGILLLQHGANINKQDTFGNSALIHCAFHNSHQELTRVLLSHGANMHLKNKSGHNAYQISQSMNNTNI 1012
G + L + I LLE G N K +TPL + + G++++ LL++H A +N G + + CA + + +L +GAN+ + K+G+ ++ N+
Sbjct: 601 GHTPLHIAARKNQMDIATTLLEYGALANAESKAG-FTPL---HLSSQEGHAEISNLLIEHKAAVNHPAKNGLTPMHLCA-QEDNVNVAEILEKNGANIDMATKAGYTPLHVASHFGQANM 715 HSP 8 Score: 34.2686 bits (77), Expect = 1.069e-6 Identity = 24/90 (26.67%), Postives = 45/90 (50.00%), Query Frame = 3
Query: 375 LHRAIIMNDEQLLLKLLQSGKINMNIPDRYDYTPLMACAIRNLEGLFACLVEYKVELDVQNKAGKTALMLAANKGNSRMVQLLLNHGANP 644
LH A +++ L+++G ++ + +TPL A + L++ + ++D Q K G T L +A + N ++ LLL GA+P
Sbjct: 506 LHIAAKEGQDEVAAVLIENGAA-LDAATKKGFTPLHLTAKYGHIKVAQLLLQKEADVDAQGKNGVTPLHVACHYNNQQVALLLLEKGASP 594 HSP 9 Score: 49.2914 bits (116), Expect = 5.282e-6 Identity = 36/102 (35.29%), Postives = 54/102 (52.94%), Query Frame = 2
Query: 662 ALFYGVDNENIIIVRMLLEAGCDVNDTDKENEWTPLIRLAVLANNGNSKLGILLLQHGANINKQDTFGNSALIHCAFHNSHQELTRVLLSHGANMHLKNKSG 967
A YG N+NI +L++ G DVN + K N + L V A G + + LLL+ G NI + G + L HCA + H+++ +LL GA + K K+G
Sbjct: 212 ASHYG--NQNI--ANLLIQKGADVNYSAKHN----ISPLHVAAKWGKTNMVSLLLEKGGNIEAKTRDGLTPL-HCAARSGHEQVVDMLLERGAPISAKTKNG 304 HSP 10 Score: 48.9062 bits (115), Expect = 7.738e-6 Identity = 37/126 (29.37%), Postives = 61/126 (48.41%), Query Frame = 2
Query: 653 GMSALFYGVDNENIIIVRMLLEAGCDVNDTDKENEWTPLIRLAVLANNGNSKLGILLLQHGANINKQDTFGNSALIHCAFHNSHQELTRVLLSHGANMHLKNKSGHNAYQISQSMNNTNITLVMEE 1030
G++AL + +I +V LL G V+ K+ + +A LA G ++ LLL+H A++N Q G + L A N H + R+LLS+GAN L + G ++ + + V+ E
Sbjct: 44 GLNALHLASKDGHIHVVSELLRRGAIVDSATKKG--NTALHIASLA--GQEEVVKLLLEHNASVNVQSQNGFTPLYMAAQEN-HDAVVRLLLSNGANQSLATEDGFTPLAVAMQQGHDKVVAVLLE 164
BLAST of Fibronectin type III and ankyrin repeat domains 1 vs. Ensembl Zebrafish
Match: fank1 (fibronectin type III and ankyrin repeat domains 1 [Source:ZFIN;Acc:ZDB-GENE-130613-3]) HSP 1 Score: 100.523 bits (249), Expect = 2.126e-23 Identity = 62/217 (28.57%), Postives = 111/217 (51.15%), Query Frame = 3
Query: 69 APAVEIVNHHMLSISWSDINKRLSLILSEEEAKCLAEISFKKINNFDEPW--IVKGYADSCELEDFDQDSVYNYRIRLRNKNGWGEYSDEKSVHFPKEPVTGDDLHRAIIMNDEQLLLKLLQSGKINMNIPDRYDYTPLMACAIRNLEGLFACLVEYKVELDVQNKAGKTALMLAANKGNSRMVQLLLNHGANPLLKE----CQLYFTVSTMKILLL 701
A AV V+HH + + WS K + C +++NN + I KGY +++ + + Y +R+++ +G +Y + K P+ G +LH A++ DE L ++LQSG + +++PDR DYTPLM AI+ LV + ++ +N +GK +LMLA G+ +V+LL GA+ ++ C L++ + ++ +L
Sbjct: 12 ALAVGQVSHHSIELVWSR-EKGSKWTDPPQNWTCFI---LEQMNNTKHSFKQIHKGYNTRFTVDNLEPKTTYTFRLKVTWPSGQQQYYPSVTASTEKPPLNGKNLHSAVLKTDEVELCRVLQSGTVTVDVPDRLDYTPLMMAAIKGFTSGVQILVHHGADVSRKNSSGKDSLMLACFHGHLDVVKLLCGCGASWRARDRTGCCSLHWATAGGQLDIL 224 HSP 2 Score: 67.781 bits (164), Expect = 3.380e-12 Identity = 38/126 (30.16%), Postives = 76/126 (60.32%), Query Frame = 2
Query: 653 GMSALFYGVDNENIIIVRMLLEAGCDVNDTDKENEWTPLIRLAVLANNGNSKLGILLLQHGANINKQDTFGNSALIHCAFHNSHQELTRVLLSHGANMHLKNKSGHNAYQISQSMNNTNITLVMEE 1030
G +L + + I++ L++ GC+VN D WTPL+ ++V+ G+ + LL+ GA++N QD G + L+ A N+++ L ++LL GA+ +++NK G +A +++++ + NI ++E+
Sbjct: 208 GCCSLHWATAGGQLDILQYLIQYGCEVNVQD-NIAWTPLMIVSVI--TGDPAVASLLISAGADVNVQDRDGKTPLM-VAVLNNYEHLVQILLKKGADPNIQNKCGVSALEMAKAFDRQNIISLLED 329
BLAST of Fibronectin type III and ankyrin repeat domains 1 vs. Ensembl Zebrafish
Match: ank1a (ankyrin 1, erythrocytic a [Source:ZFIN;Acc:ZDB-GENE-041010-44]) HSP 1 Score: 51.9878 bits (123), Expect = 5.817e-13 Identity = 37/105 (35.24%), Postives = 52/105 (49.52%), Query Frame = 2
Query: 653 GMSALFYGVDNENIIIVRMLLEAGCDVNDTDKENEWTPLIRLAVLANNGNSKLGILLLQHGANINKQDTFGNSALIHCAFHNSHQELTRVLLSHGANMHLKNKSG 967
G + L EN+ + ++LL G DVN T K N TPL + + GN + LLL GA I+ + T +HCA N H + +LL GA + K K+G
Sbjct: 206 GFTPLHIAAHYENLNVAQLLLNRGADVNFTPK-NGITPL---HIASRRGNVIMVRLLLDRGAKIDAK-TKDELTPLHCAARNGHVRIIEILLDQGAPIQAKTKNG 305 HSP 2 Score: 41.2022 bits (95), Expect = 5.817e-13 Identity = 26/87 (29.89%), Postives = 44/87 (50.57%), Query Frame = 3
Query: 375 LHRAIIMNDEQLLLKLLQSGKINMNIPDRYDYTPLMACAIRNLEGLFACLVEYKVELDVQNKAGKTALMLAANKGNSRMVQLLLNHG 635
LH A + EQ++ +L+ G N+N + +TPL A N + L++ + + G T L +A +G+ +V LL+NHG
Sbjct: 82 LHIAALAGQEQVVTELVNYGA-NVNAQSQKGFTPLYMAAQENHLEVVKFLLDNGANQTIPTEDGFTPLAVALQQGHENVVALLINHG 167 HSP 3 Score: 46.595 bits (109), Expect = 1.260e-10 Identity = 32/105 (30.48%), Postives = 55/105 (52.38%), Query Frame = 2
Query: 653 GMSALFYGVDNENIIIVRMLLEAGCDVNDTDKENEWTPLIRLAVLANNGNSKLGILLLQHGANINKQDTFGNSALIHCAFHNSHQELTRVLLSHGANMHLKNKSG 967
G++ L V + N+ +V +LL G + + N +TPL + + +++ LLQHGA+ N + G + L H A ++ +L+S AN++L NKSG
Sbjct: 569 GLTPLHVAVHHNNLDVVNLLLSKGGSPHSAAR-NGYTPL---HIASKQNQAEVASSLLQHGASANAESLQGVTPL-HLASQEGQPDMVLLLISKQANVNLGNKSG 668 HSP 4 Score: 38.5058 bits (88), Expect = 1.260e-10 Identity = 30/90 (33.33%), Postives = 40/90 (44.44%), Query Frame = 3
Query: 375 LHRAIIMNDEQLLLKLLQSGKINMNIPDRYDYTPLMACAIRNLEGLFACLVEYKVELDVQNKAGKTALMLAANKGNSRMVQLLLNHGANP 644
LH A M +++ KLL K N N +TPL A + L++ +L K G T L +AA G + LLL GANP
Sbjct: 474 LHCASRMGHNEMV-KLLLEHKANSNSTTTAGHTPLHIAAREGHTQTASILLDMNAQLTKMTKKGFTPLHVAAKYGKVDVAVLLLERGANP 562 HSP 5 Score: 42.3578 bits (98), Expect = 1.491e-7 Identity = 24/79 (30.38%), Postives = 40/79 (50.63%), Query Frame = 2
Query: 776 LAVLANNGNSKLGILLLQHGANINKQDTFGNSALIHCAFHNSHQELTRVLLSHGANMHLKNKSGHNAYQISQSMNNTNI 1012
L V A G + +LLL+ GAN N G + L H A H+++ ++ +LLS G + H ++G+ I+ N +
Sbjct: 540 LHVAAKYGKVDVAVLLLERGANPNAAGKVGLTPL-HVAVHHNNLDVVNLLLSKGGSPHSAARNGYTPLHIASKQNQAEV 617 HSP 6 Score: 32.3426 bits (72), Expect = 1.491e-7 Identity = 21/70 (30.00%), Postives = 34/70 (48.57%), Query Frame = 3
Query: 465 DYTPLMACAIRNLEGLFACLVEYKVELDVQNKAGKTALMLAANKGNSRMVQLLLNHGANPLLKECQLYFT 674
D TPL + + L+E+K + AG T L +AA +G+++ +LL+ A L K + FT
Sbjct: 470 DQTPLHCASRMGHNEMVKLLLEHKANSNSTTTAGHTPLHIAAREGHTQTASILLDMNAQ-LTKMTKKGFT 538 HSP 7 Score: 38.1206 bits (87), Expect = 1.698e-6 Identity = 33/127 (25.98%), Postives = 55/127 (43.31%), Query Frame = 2
Query: 650 KGMSALFYGVDNENIIIVRMLLEAGCDVNDTDKENEWTPLIRLAVLANNGNSKLGILLLQHGANINKQDTFGNSAL--IHCAFHNSHQELTRVLLSHGANMHLKNKSGHNAYQISQSMNNTNITLVM 1024
KG + L+ ++ +V+ LL+ G + E+ +TPL AV G+ + LL+ HG T G L +H A N VLL + N + +K+G I+ N N+ ++
Sbjct: 110 KGFTPLYMAAQENHLEVVKFLLDNGAN-QTIPTEDGFTPL---AVALQQGHENVVALLINHG-------TKGKVRLPALHIAARNDDTRTAAVLLQNDPNPDVLSKTGFTPLHIAAHYENLNVAQLL 225 HSP 8 Score: 33.113 bits (74), Expect = 1.698e-6 Identity = 16/40 (40.00%), Postives = 25/40 (62.50%), Query Frame = 3
Query: 522 LVEYKVELDVQNKAGKTALMLAANKGNSRMVQLLLNHGAN 641
L+ + + L+ K G TAL +AA G ++V L+N+GAN
Sbjct: 64 LLHHGIVLETTTKKGNTALHIAALAGQEQVVTELVNYGAN 103
BLAST of Fibronectin type III and ankyrin repeat domains 1 vs. Ensembl Zebrafish
Match: dapk1 (death-associated protein kinase 1 [Source:ZFIN;Acc:ZDB-GENE-060526-177]) HSP 1 Score: 50.0618 bits (118), Expect = 3.379e-12 Identity = 32/97 (32.99%), Postives = 52/97 (53.61%), Query Frame = 2
Query: 698 IVRMLLEAGCDVNDTDKENEWTPLIRLAVLANNGNSKLGILLLQHGANINKQDTFGNSALIHCAFHNSHQELTRVLLSHGANMHLKNKSGHNAYQIS 988
+ R L EAGCDVN ++E E +PL+ + G + LL+HGA+++ D G+ AL H A E+ + LLSH + +++ G+ I+
Sbjct: 493 VARALCEAGCDVNARNREGE-SPLLTASA---RGFKDIVECLLEHGADMDSADKDGHIAL-HLAVRRCQVEVVKCLLSHHCYVDHQDRHGNTPLHIA 584 HSP 2 Score: 40.817 bits (94), Expect = 3.379e-12 Identity = 24/63 (38.10%), Postives = 34/63 (53.97%), Query Frame = 3
Query: 456 DRYDYTPLMACAIRNLEGLFACLVEYKVELDVQNKAGKTALMLAANKGNSRMVQLLLNHGANP 644
D+ + + A G L E K LD+Q+K+G+TAL +AA GN +VQ L + ANP
Sbjct: 409 DKTGASAIYYAARHGHVGTLRFLHEKKCPLDIQDKSGETALHVAARYGNVDVVQYLCSIHANP 471
BLAST of Fibronectin type III and ankyrin repeat domains 1 vs. Ensembl Zebrafish
Match: dapk1 (death-associated protein kinase 1 [Source:ZFIN;Acc:ZDB-GENE-060526-177]) HSP 1 Score: 50.0618 bits (118), Expect = 3.379e-12 Identity = 32/97 (32.99%), Postives = 52/97 (53.61%), Query Frame = 2
Query: 698 IVRMLLEAGCDVNDTDKENEWTPLIRLAVLANNGNSKLGILLLQHGANINKQDTFGNSALIHCAFHNSHQELTRVLLSHGANMHLKNKSGHNAYQIS 988
+ R L EAGCDVN ++E E +PL+ + G + LL+HGA+++ D G+ AL H A E+ + LLSH + +++ G+ I+
Sbjct: 493 VARALCEAGCDVNARNREGE-SPLLTASA---RGFKDIVECLLEHGADMDSADKDGHIAL-HLAVRRCQVEVVKCLLSHHCYVDHQDRHGNTPLHIA 584 HSP 2 Score: 40.817 bits (94), Expect = 3.379e-12 Identity = 24/63 (38.10%), Postives = 34/63 (53.97%), Query Frame = 3
Query: 456 DRYDYTPLMACAIRNLEGLFACLVEYKVELDVQNKAGKTALMLAANKGNSRMVQLLLNHGANP 644
D+ + + A G L E K LD+Q+K+G+TAL +AA GN +VQ L + ANP
Sbjct: 409 DKTGASAIYYAARHGHVGTLRFLHEKKCPLDIQDKSGETALHVAARYGNVDVVQYLCSIHANP 471
BLAST of Fibronectin type III and ankyrin repeat domains 1 vs. Ensembl Zebrafish
Match: dapk1 (death-associated protein kinase 1 [Source:ZFIN;Acc:ZDB-GENE-060526-177]) HSP 1 Score: 50.0618 bits (118), Expect = 3.517e-12 Identity = 32/97 (32.99%), Postives = 52/97 (53.61%), Query Frame = 2
Query: 698 IVRMLLEAGCDVNDTDKENEWTPLIRLAVLANNGNSKLGILLLQHGANINKQDTFGNSALIHCAFHNSHQELTRVLLSHGANMHLKNKSGHNAYQIS 988
+ R L EAGCDVN ++E E +PL+ + G + LL+HGA+++ D G+ AL H A E+ + LLSH + +++ G+ I+
Sbjct: 531 VARALCEAGCDVNARNREGE-SPLLTASA---RGFKDIVECLLEHGADMDSADKDGHIAL-HLAVRRCQVEVVKCLLSHHCYVDHQDRHGNTPLHIA 622 HSP 2 Score: 40.4318 bits (93), Expect = 3.517e-12 Identity = 24/63 (38.10%), Postives = 34/63 (53.97%), Query Frame = 3
Query: 456 DRYDYTPLMACAIRNLEGLFACLVEYKVELDVQNKAGKTALMLAANKGNSRMVQLLLNHGANP 644
D+ + + A G L E K LD+Q+K+G+TAL +AA GN +VQ L + ANP
Sbjct: 447 DKTGASAIYYAARHGHVGTLRFLHEKKCPLDIQDKSGETALHVAARYGNVDVVQYLCSIHANP 509
BLAST of Fibronectin type III and ankyrin repeat domains 1 vs. Ensembl Xenopus
Match: FANK1 (fibronectin type III and ankyrin repeat domains 1 [Source:NCBI gene;Acc:100495570]) HSP 1 Score: 103.99 bits (258), Expect = 9.525e-39 Identity = 67/201 (33.33%), Postives = 104/201 (51.74%), Query Frame = 3
Query: 42 NTKIPPKIPAPAVEIVNHHMLSISWSDINKRLSLILSEEE-AKCLAEISFKKINNFDEPWIVKGYADSCELEDFDQDSVYNYRIRLRNKNGWGEYSDEKSVHFPKEPVTGDDLHRAIIMNDEQLLLKLLQSGKINMNIPDRYDYTPLMACAIRNLEGLFACLVEYKVELDVQNKAGKTALMLAANKGNSRMVQLLLNHGAN 641
NT + P P + V+HH + + W DIN L S + K E K + F I GY+ +E + S Y +R+++ NG YS SV +EP++G LHRA+ MNDE + +L++G + ++IPD+ +TPLM A + L L E+ +++ N +GK +LMLA G+ +VQ L GA+
Sbjct: 7 NTILKPD--PPVIGKVSHHSIELYW-DINNNLKQKSSSNKWIKFTIEEEDIKTHVFGT--IYSGYSRRHTVEGLEPSSPYRFRLKVTGYNGDYAYSPVVSVSTTREPLSGQHLHRAVNMNDEHEVKNILETGHVKVDIPDKLGFTPLMVAAQKGFLRLVELLTEHGADINQMNGSGKNSLMLACFAGHLNIVQYLRGQGAS 202 HSP 2 Score: 76.6406 bits (187), Expect = 9.525e-39 Identity = 37/125 (29.60%), Postives = 75/125 (60.00%), Query Frame = 2
Query: 653 GMSALFYGVDNENIIIVRMLLEAGCDVNDTDKENEWTPLIRLAVLANNGNSKLGILLLQHGANINKQDTFGNSALIHCAFHNSHQELTRVLLSHGANMHLKNKSGHNAYQISQSMNNTNITLVME 1027
G +A+ + D ++ +V+ +++ GC ++ D EWTPL+R+A ++ GN + L+ GA +N +DT G + L+ A N+H+ L +LL +GA+ +KN+ G +++++ N ++ ++E
Sbjct: 210 GCTAMHWAADGGHLKVVQWMIDDGCKIDSRDSHLEWTPLMRIAAVS--GNVDIARCLIAAGAGVNAKDTNGKTPLM-VAVLNNHESLVHLLLENGADRSIKNEFGIGMTEMAKAFNRESVVAILE 331
BLAST of Fibronectin type III and ankyrin repeat domains 1 vs. Ensembl Xenopus
Match: FANK1 (fibronectin type III and ankyrin repeat domains 1 [Source:NCBI gene;Acc:100495570]) HSP 1 Score: 104.375 bits (259), Expect = 1.069e-38 Identity = 67/201 (33.33%), Postives = 104/201 (51.74%), Query Frame = 3
Query: 42 NTKIPPKIPAPAVEIVNHHMLSISWSDINKRLSLILSEEE-AKCLAEISFKKINNFDEPWIVKGYADSCELEDFDQDSVYNYRIRLRNKNGWGEYSDEKSVHFPKEPVTGDDLHRAIIMNDEQLLLKLLQSGKINMNIPDRYDYTPLMACAIRNLEGLFACLVEYKVELDVQNKAGKTALMLAANKGNSRMVQLLLNHGAN 641
NT + P P + V+HH + + W DIN L S + K E K + F I GY+ +E + S Y +R+++ NG YS SV +EP++G LHRA+ MNDE + +L++G + ++IPD+ +TPLM A + L L E+ +++ N +GK +LMLA G+ +VQ L GA+
Sbjct: 9 NTILKPD--PPVIGKVSHHSIELYW-DINNNLKQKSSSNKWIKFTIEEEDIKTHVFGT--IYSGYSRRHTVEGLEPSSPYRFRLKVTGYNGDYAYSPVVSVSTTREPLSGQHLHRAVNMNDEHEVKNILETGHVKVDIPDKLGFTPLMVAAQKGFLRLVELLTEHGADINQMNGSGKNSLMLACFAGHLNIVQYLRGQGAS 204 HSP 2 Score: 76.2554 bits (186), Expect = 1.069e-38 Identity = 37/125 (29.60%), Postives = 75/125 (60.00%), Query Frame = 2
Query: 653 GMSALFYGVDNENIIIVRMLLEAGCDVNDTDKENEWTPLIRLAVLANNGNSKLGILLLQHGANINKQDTFGNSALIHCAFHNSHQELTRVLLSHGANMHLKNKSGHNAYQISQSMNNTNITLVME 1027
G +A+ + D ++ +V+ +++ GC ++ D EWTPL+R+A ++ GN + L+ GA +N +DT G + L+ A N+H+ L +LL +GA+ +KN+ G +++++ N ++ ++E
Sbjct: 212 GCTAMHWAADGGHLKVVQWMIDDGCKIDSRDSHLEWTPLMRIAAVS--GNVDIARCLIAAGAGVNAKDTNGKTPLM-VAVLNNHESLVHLLLENGADRSIKNEFGIGMTEMAKAFNRESVVAILE 333
BLAST of Fibronectin type III and ankyrin repeat domains 1 vs. Ensembl Xenopus
Match: FANK1 (fibronectin type III and ankyrin repeat domains 1 [Source:NCBI gene;Acc:100495570]) HSP 1 Score: 104.375 bits (259), Expect = 1.776e-37 Identity = 68/207 (32.85%), Postives = 106/207 (51.21%), Query Frame = 3
Query: 24 ITLLMSNTKIPPKIPAPAVEIVNHHMLSISWSDINKRLSLILSEEE-AKCLAEISFKKINNFDEPWIVKGYADSCELEDFDQDSVYNYRIRLRNKNGWGEYSDEKSVHFPKEPVTGDDLHRAIIMNDEQLLLKLLQSGKINMNIPDRYDYTPLMACAIRNLEGLFACLVEYKVELDVQNKAGKTALMLAANKGNSRMVQLLLNHGAN 641
I + NT + P P + V+HH + + W DIN L S + K E K + F I GY+ +E + S Y +R+++ NG YS SV +EP++G LHRA+ MNDE + +L++G + ++IPD+ +TPLM A + L L E+ +++ N +GK +LMLA G+ +VQ L GA+
Sbjct: 2 IEHIYQNTILKPD--PPVIGKVSHHSIELYW-DINNNLKQKSSSNKWIKFTIEEEDIKTHVFGT--IYSGYSRRHTVEGLEPSSPYRFRLKVTGYNGDYAYSPVVSVSTTREPLSGQHLHRAVNMNDEHEVKNILETGHVKVDIPDKLGFTPLMVAAQKGFLRLVELLTEHGADINQMNGSGKNSLMLACFAGHLNIVQYLRGQGAS 203 HSP 2 Score: 72.0182 bits (175), Expect = 1.776e-37 Identity = 36/116 (31.03%), Postives = 70/116 (60.34%), Query Frame = 2
Query: 653 GMSALFYGVDNENIIIVRMLLEAGCDVNDTDKENEWTPLIRLAVLANNGNSKLGILLLQHGANINKQDTFGNSALIHCAFHNSHQELTRVLLSHGANMHLKNKSGHNAYQISQSMN 1000
G +A+ + D ++ +V+ +++ GC ++ D EWTPL+R+A ++ GN + L+ GA +N +DT G + L+ A N+H+ L +LL +GA+ +KN+ G +++++ N
Sbjct: 211 GCTAMHWAADGGHLKVVQWMIDDGCKIDSRDSHLEWTPLMRIAAVS--GNVDIARCLIAAGAGVNAKDTNGKTPLM-VAVLNNHESLVHLLLENGADRSIKNEFGIGMTEMAKAFN 323
BLAST of Fibronectin type III and ankyrin repeat domains 1 vs. Ensembl Xenopus
Match: FANK1 (fibronectin type III and ankyrin repeat domains 1 [Source:NCBI gene;Acc:100495570]) HSP 1 Score: 103.99 bits (258), Expect = 2.295e-37 Identity = 64/191 (33.51%), Postives = 100/191 (52.36%), Query Frame = 3
Query: 72 PAVEIVNHHMLSISWSDINKRLSLILSEEE-AKCLAEISFKKINNFDEPWIVKGYADSCELEDFDQDSVYNYRIRLRNKNGWGEYSDEKSVHFPKEPVTGDDLHRAIIMNDEQLLLKLLQSGKINMNIPDRYDYTPLMACAIRNLEGLFACLVEYKVELDVQNKAGKTALMLAANKGNSRMVQLLLNHGAN 641
P + V+HH + + W DIN L S + K E K + F I GY+ +E + S Y +R+++ NG YS SV +EP++G LHRA+ MNDE + +L++G + ++IPD+ +TPLM A + L L E+ +++ N +GK +LMLA G+ +VQ L GA+
Sbjct: 19 PVIGKVSHHSIELYW-DINNNLKQKSSSNKWIKFTIEEEDIKTHVFGT--IYSGYSRRHTVEGLEPSSPYRFRLKVTGYNGDYAYSPVVSVSTTREPLSGQHLHRAVNMNDEHEVKNILETGHVKVDIPDKLGFTPLMVAAQKGFLRLVELLTEHGADINQMNGSGKNSLMLACFAGHLNIVQYLRGQGAS 206 HSP 2 Score: 72.0182 bits (175), Expect = 2.295e-37 Identity = 36/116 (31.03%), Postives = 70/116 (60.34%), Query Frame = 2
Query: 653 GMSALFYGVDNENIIIVRMLLEAGCDVNDTDKENEWTPLIRLAVLANNGNSKLGILLLQHGANINKQDTFGNSALIHCAFHNSHQELTRVLLSHGANMHLKNKSGHNAYQISQSMN 1000
G +A+ + D ++ +V+ +++ GC ++ D EWTPL+R+A ++ GN + L+ GA +N +DT G + L+ A N+H+ L +LL +GA+ +KN+ G +++++ N
Sbjct: 214 GCTAMHWAADGGHLKVVQWMIDDGCKIDSRDSHLEWTPLMRIAAVS--GNVDIARCLIAAGAGVNAKDTNGKTPLM-VAVLNNHESLVHLLLENGADRSIKNEFGIGMTEMAKAFN 326
BLAST of Fibronectin type III and ankyrin repeat domains 1 vs. Ensembl Xenopus
Match: FANK1 (fibronectin type III and ankyrin repeat domains 1 [Source:NCBI gene;Acc:100495570]) HSP 1 Score: 103.99 bits (258), Expect = 2.295e-37 Identity = 67/201 (33.33%), Postives = 104/201 (51.74%), Query Frame = 3
Query: 42 NTKIPPKIPAPAVEIVNHHMLSISWSDINKRLSLILSEEE-AKCLAEISFKKINNFDEPWIVKGYADSCELEDFDQDSVYNYRIRLRNKNGWGEYSDEKSVHFPKEPVTGDDLHRAIIMNDEQLLLKLLQSGKINMNIPDRYDYTPLMACAIRNLEGLFACLVEYKVELDVQNKAGKTALMLAANKGNSRMVQLLLNHGAN 641
NT + P P + V+HH + + W DIN L S + K E K + F I GY+ +E + S Y +R+++ NG YS SV +EP++G LHRA+ MNDE + +L++G + ++IPD+ +TPLM A + L L E+ +++ N +GK +LMLA G+ +VQ L GA+
Sbjct: 7 NTILKPD--PPVIGKVSHHSIELYW-DINNNLKQKSSSNKWIKFTIEEEDIKTHVFGT--IYSGYSRRHTVEGLEPSSPYRFRLKVTGYNGDYAYSPVVSVSTTREPLSGQHLHRAVNMNDEHEVKNILETGHVKVDIPDKLGFTPLMVAAQKGFLRLVELLTEHGADINQMNGSGKNSLMLACFAGHLNIVQYLRGQGAS 202 HSP 2 Score: 72.0182 bits (175), Expect = 2.295e-37 Identity = 36/116 (31.03%), Postives = 70/116 (60.34%), Query Frame = 2
Query: 653 GMSALFYGVDNENIIIVRMLLEAGCDVNDTDKENEWTPLIRLAVLANNGNSKLGILLLQHGANINKQDTFGNSALIHCAFHNSHQELTRVLLSHGANMHLKNKSGHNAYQISQSMN 1000
G +A+ + D ++ +V+ +++ GC ++ D EWTPL+R+A ++ GN + L+ GA +N +DT G + L+ A N+H+ L +LL +GA+ +KN+ G +++++ N
Sbjct: 210 GCTAMHWAADGGHLKVVQWMIDDGCKIDSRDSHLEWTPLMRIAAVS--GNVDIARCLIAAGAGVNAKDTNGKTPLM-VAVLNNHESLVHLLLENGADRSIKNEFGIGMTEMAKAFN 322
BLAST of Fibronectin type III and ankyrin repeat domains 1 vs. Ensembl Mouse
Match: Fank1 (fibronectin type 3 and ankyrin repeat domains 1 [Source:MGI Symbol;Acc:MGI:1914180]) HSP 1 Score: 104.76 bits (260), Expect = 5.106e-39 Identity = 60/203 (29.56%), Postives = 109/203 (53.69%), Query Frame = 3
Query: 36 MSNTKIPPKIP-APAVEIVNHHMLSISWSDINKRLSLILSEEEAKCLAEISFKKINNFDEPWIVKGYADSCELEDFDQDSVYNYRIRLRNKNGWGEYSDEKSVHFPKEPVTGDDLHRAIIMNDEQLLLKLLQSGKINMNIPDRYDYTPLMACAIRNLEGLFACLVEYKVELDVQNKAGKTALMLAANKGNSRMVQLLLNHGAN 641
M+ +P P P V V HH + + W K E+ + E K++++ I GYA +E + ++Y +R+++ + +G EYS SV +EP++ + HRA+ +NDE LLL++L+ G + +++P+++ +T LM A + L LV +++++N +GK +LMLA G+ +V+ L HGA+
Sbjct: 1 MTTEVVPLSKPHPPVVGKVTHHSIELYWDLEQKEKRQGPQEQWLRFSIEEEDPKMHSYGV--IYTGYATRHVVEGLEPRTLYKFRLKVTSPSGEYEYSPVVSVATTREPISSEHFHRAVSVNDEDLLLRILEGGHVMIDVPNKFGFTALMVAAQKGYTRLVKILVSNGTDVNLKNGSGKDSLMLACYAGHLDVVKYLRRHGAS 201 HSP 2 Score: 76.6406 bits (187), Expect = 5.106e-39 Identity = 38/126 (30.16%), Postives = 77/126 (61.11%), Query Frame = 2
Query: 653 GMSALFYGVDNENIIIVRMLLEAGCDVNDTDKENEWTPLIRLAVLANNGNSKLGILLLQHGANINKQDTFGNSALIHCAFHNSHQELTRVLLSHGANMHLKNKSGHNAYQISQSMNNTNITLVMEE 1030
G +AL + D + ++ +++ GC+V+ D + WTPL+R++ A G+ K+ LL++ GA++N +D G + L+ A N+H++L ++LL GA+ +KN+ G ++++ + N+ ++EE
Sbjct: 209 GCTALHWAADGGHCSVIDWMIKDGCEVDVVDTGSGWTPLMRVS--AVTGSQKVASLLIEAGADVNIKDKDGKTPLM-VAVLNNHEQLVQLLLDKGADATVKNEFGKGVLEMARVFDRQNVLSLLEE 331
BLAST of Fibronectin type III and ankyrin repeat domains 1 vs. Ensembl Mouse
Match: Fank1 (fibronectin type 3 and ankyrin repeat domains 1 [Source:MGI Symbol;Acc:MGI:1914180]) HSP 1 Score: 103.605 bits (257), Expect = 1.206e-38 Identity = 57/190 (30.00%), Postives = 104/190 (54.74%), Query Frame = 3
Query: 72 PAVEIVNHHMLSISWSDINKRLSLILSEEEAKCLAEISFKKINNFDEPWIVKGYADSCELEDFDQDSVYNYRIRLRNKNGWGEYSDEKSVHFPKEPVTGDDLHRAIIMNDEQLLLKLLQSGKINMNIPDRYDYTPLMACAIRNLEGLFACLVEYKVELDVQNKAGKTALMLAANKGNSRMVQLLLNHGAN 641
P V V HH + + W K E+ + E K++++ I GYA +E + ++Y +R+++ + +G EYS SV +EP++ + HRA+ +NDE LLL++L+ G + +++P+++ +T LM A + L LV +++++N +GK +LMLA G+ +V+ L HGA+
Sbjct: 15 PVVGKVTHHSIELYWDLEQKEKRQGPQEQWLRFSIEEEDPKMHSYGV--IYTGYATRHVVEGLEPRTLYKFRLKVTSPSGEYEYSPVVSVATTREPISSEHFHRAVSVNDEDLLLRILEGGHVMIDVPNKFGFTALMVAAQKGYTRLVKILVSNGTDVNLKNGSGKDSLMLACYAGHLDVVKYLRRHGAS 202 HSP 2 Score: 76.2554 bits (186), Expect = 1.206e-38 Identity = 38/126 (30.16%), Postives = 77/126 (61.11%), Query Frame = 2
Query: 653 GMSALFYGVDNENIIIVRMLLEAGCDVNDTDKENEWTPLIRLAVLANNGNSKLGILLLQHGANINKQDTFGNSALIHCAFHNSHQELTRVLLSHGANMHLKNKSGHNAYQISQSMNNTNITLVMEE 1030
G +AL + D + ++ +++ GC+V+ D + WTPL+R++ A G+ K+ LL++ GA++N +D G + L+ A N+H++L ++LL GA+ +KN+ G ++++ + N+ ++EE
Sbjct: 210 GCTALHWAADGGHCSVIDWMIKDGCEVDVVDTGSGWTPLMRVS--AVTGSQKVASLLIEAGADVNIKDKDGKTPLM-VAVLNNHEQLVQLLLDKGADATVKNEFGKGVLEMARVFDRQNVLSLLEE 332
BLAST of Fibronectin type III and ankyrin repeat domains 1 vs. Ensembl Mouse
Match: Fank1 (fibronectin type 3 and ankyrin repeat domains 1 [Source:MGI Symbol;Acc:MGI:1914180]) HSP 1 Score: 98.9821 bits (245), Expect = 1.488e-24 Identity = 47/141 (33.33%), Postives = 86/141 (60.99%), Query Frame = 3
Query: 219 IVKGYADSCELEDFDQDSVYNYRIRLRNKNGWGEYSDEKSVHFPKEPVTGDDLHRAIIMNDEQLLLKLLQSGKINMNIPDRYDYTPLMACAIRNLEGLFACLVEYKVELDVQNKAGKTALMLAANKGNSRMVQLLLNHGAN 641
I GYA +E + ++Y +R+++ + +G EYS SV +EP++ + HRA+ +NDE LLL++L+ G + +++P+++ +T LM A + L LV +++++N +GK +LMLA G+ +V+ L HGA+
Sbjct: 7 IYTGYATRHVVEGLEPRTLYKFRLKVTSPSGEYEYSPVVSVATTREPISSEHFHRAVSVNDEDLLLRILEGGHVMIDVPNKFGFTALMVAAQKGYTRLVKILVSNGTDVNLKNGSGKDSLMLACYAGHLDVVKYLRRHGAS 147
BLAST of Fibronectin type III and ankyrin repeat domains 1 vs. Ensembl Mouse
Match: Fank1 (fibronectin type 3 and ankyrin repeat domains 1 [Source:MGI Symbol;Acc:MGI:1914180]) HSP 1 Score: 71.2478 bits (173), Expect = 5.118e-15 Identity = 30/88 (34.09%), Postives = 57/88 (64.77%), Query Frame = 3
Query: 219 IVKGYADSCELEDFDQDSVYNYRIRLRNKNGWGEYSDEKSVHFPKEPVTGDDLHRAIIMNDEQLLLKLLQSGKINMNIPDRYDYTPLM 482
I GYA +E + ++Y +R+++ + +G EYS SV +EP++ + HRA+ +NDE LLL++L+ G + +++P+++ +T LM
Sbjct: 7 IYTGYATRHVVEGLEPRTLYKFRLKVTSPSGEYEYSPVVSVATTREPISSEHFHRAVSVNDEDLLLRILEGGHVMIDVPNKFGFTALM 94
BLAST of Fibronectin type III and ankyrin repeat domains 1 vs. Ensembl Mouse
Match: Ank2 (ankyrin 2, brain [Source:MGI Symbol;Acc:MGI:88025]) HSP 1 Score: 50.8322 bits (120), Expect = 6.778e-15 Identity = 34/115 (29.57%), Postives = 57/115 (49.57%), Query Frame = 2
Query: 653 GMSALFYGVDNENIIIVRMLLEAGCDVNDTDKENEWTPLIRLAVLANNGNSKLGILLLQHGANINKQDTFGNSALIHCAFHNSHQELTRVLLSHGANMHLKNKSGHNAYQISQSM 997
G+++L + + + +L + G D D + +TPLI V + GN K+ LL+ GAN+N + G + L H A H + VLL HGA + +G+ A I++ +
Sbjct: 695 GLTSLHLAAQEDKVNVADILTKHGAD-RDAYTKLGYTPLI---VACHYGNVKMVNFLLKQGANVNAKTKNGYTPL-HQAAQQGHTHIINVLLQHGAKPNATTANGNTALAIAKRL 804 HSP 2 Score: 48.9062 bits (115), Expect = 6.778e-15 Identity = 31/89 (34.83%), Postives = 50/89 (56.18%), Query Frame = 3
Query: 375 LHRAIIMNDEQLLLKLLQSGKINMNIPDRYDYTPLMACAIRNLEGLFACLVEYKVELDVQNKAGKTALMLAANKGNSRMVQLLLNHGAN 641
LH A +++++ L LL+ G + + + YTPL A +N + + L+ Y E + K G T L LA+ +G++ MV LLL+ GAN
Sbjct: 600 LHVAAHYDNQKVALLLLEKGA-SPHATAKNGYTPLHIAAKKNQMQIASTLLNYGAETNTVTKQGVTPLHLASQEGHTDMVTLLLDKGAN 687 HSP 3 Score: 41.2022 bits (95), Expect = 3.370e-7 Identity = 30/125 (24.00%), Postives = 59/125 (47.20%), Query Frame = 2
Query: 650 KGMSALFYGVDNENIIIVRMLLEAGCDVNDTDKENEWTPLIRLAVLANNGNSKLGILLLQHGANINKQDTFGNSALIHCAFHNSHQELTRVLLSHGANMHLKNKSGHNAYQISQSMNNTNITLVM 1024
+G++ L + +V +LL+ G +++ + K L L + A + +L +HGA+ + G + LI A H + ++ LL GAN++ K K+G+ + +T+I V+
Sbjct: 661 QGVTPLHLASQEGHTDMVTLLLDKGANIHMSTKSG----LTSLHLAAQEDKVNVADILTKHGADRDAYTKLGYTPLI-VACHYGNVKMVNFLLKQGANVNAKTKNGYTPLHQAAQQGHTHIINVL 780 HSP 4 Score: 32.3426 bits (72), Expect = 3.370e-7 Identity = 22/75 (29.33%), Postives = 38/75 (50.67%), Query Frame = 3
Query: 420 LLQSGKINMNIPDRYDYTPLMACAIRNLEGLFACLVEYKVELDVQNKAGKTALMLAANKGNSRMVQLLLNHGANP 644
LL++G + ++ + +TPL A + L++ + D K G T L +AA+ N ++ LLL GA+P
Sbjct: 549 LLEAGAAH-SLATKKGFTPLHVAAKYGSLDVAKLLLQRRAAADSAGKNGLTPLHVAAHYDNQKVALLLLEKGASP 622 HSP 5 Score: 51.6026 bits (122), Expect = 1.434e-6 Identity = 34/124 (27.42%), Postives = 58/124 (46.77%), Query Frame = 2
Query: 653 GMSALFYGVDNENIIIVRMLLEAGCDVNDTDKENEWTPLIRLAVLANNGNSKLGILLLQHGANINKQDTFGNSALIHCAFHNSHQELTRVLLSHGANMHLKNKSGHNAYQISQSMNNTNITLVM 1024
G++ L +N + +LLE G + T K N +TPL + A ++ LL +GA N G + L H A H ++ +LL GAN+H+ KSG + ++ + N+ ++
Sbjct: 596 GLTPLHVAAHYDNQKVALLLLEKGASPHATAK-NGYTPL---HIAAKKNQMQIASTLLNYGAETNTVTKQGVTPL-HLASQEGHTDMVTLLLDKGANIHMSTKSGLTSLHLAAQEDKVNVADIL 714 HSP 6 Score: 38.891 bits (89), Expect = 5.097e-6 Identity = 33/133 (24.81%), Postives = 61/133 (45.86%), Query Frame = 2
Query: 647 FKGMSALFYGVDNENIIIVRMLLEAGCDVNDTDKENEWTPLIRLAVLANNGNSKLGILLLQHGANINKQDTFGNSALIHCAFHNSHQELTRVLLSHGANMHLKNKSGHNAYQISQSMNNTNIT-LVMEEFLNP 1042
G + L I ++ +L++ G + E+ TP+ V A G+ + +LLLQ+GA+ + + G +AL H A E+ R LL +GA + + + I+ + T I L+++ +P
Sbjct: 396 LNGFTPLHIACKKNRIKVMELLVKYGASIQAI-TESGLTPI---HVAAFMGHLNIVLLLLQNGASPDVTNIRGETAL-HMAARAGQVEVVRCLLRNGALVDARAREEQTPLHIASRLGKTEIVQLLLQHMAHP 523 HSP 7 Score: 30.4166 bits (67), Expect = 5.097e-6 Identity = 17/41 (41.46%), Postives = 26/41 (63.41%), Query Frame = 3
Query: 522 LVEYKVELDVQNKAGKTALMLAANKGNSRMVQLLLNHGANP 644
L++YK +D TAL +AA+ G+ R+ +LLL+ ANP
Sbjct: 351 LLQYKAPVDDVTLDYLTALHVAAHCGHYRVTKLLLDKRANP 391
BLAST of Fibronectin type III and ankyrin repeat domains 1 vs. UniProt/SwissProt
Match: sp|Q8TC84|FANK1_HUMAN (Fibronectin type 3 and ankyrin repeat domains protein 1 OS=Homo sapiens OX=9606 GN=FANK1 PE=1 SV=3) HSP 1 Score: 109.768 bits (273), Expect = 1.442e-40 Identity = 62/199 (31.16%), Postives = 113/199 (56.78%), Query Frame = 3
Query: 51 IPPKIP-APAVEIVNHHMLSISWSDINKRLSLILSEEE-AKCLAEISFKKINNFDEPWIVKGYADSCELEDFDQDSVYNYRIRLRNKNGWGEYSDEKSVHFPKEPVTGDDLHRAIIMNDEQLLLKLLQSGKINMNIPDRYDYTPLMACAIRNLEGLFACLVEYKVELDVQNKAGKTALMLAANKGNSRMVQLLLNHGAN 641
+PP P P V V HH + + W D+ K+ +E+ + E K++ + I GYA +E + ++Y +R+++ + +G EYS SV +EP++ + LHRA+ +NDE LL+++LQ G++ +++P+++ +T LM A + L LV +++++N +GK +LMLA G+ +V+ L HGA+
Sbjct: 7 MPPSKPHPPVVGKVTHHSIELYW-DLEKKAKRQGPQEQWFRFSIEEEDPKMHTYG--IIYTGYATKHVVEGLEPRTLYRFRLKVTSPSGECEYSPLVSVSTTREPISSEHLHRAVSVNDEDLLVRILQGGRVKVDVPNKFGFTALMVAAQKGYTRLVKILVSNGTDVNLKNGSGKDSLMLACYAGHLDVVKYLRRHGAS 202 HSP 2 Score: 78.9518 bits (193), Expect = 1.442e-40 Identity = 39/126 (30.95%), Postives = 77/126 (61.11%), Query Frame = 2
Query: 653 GMSALFYGVDNENIIIVRMLLEAGCDVNDTDKENEWTPLIRLAVLANNGNSKLGILLLQHGANINKQDTFGNSALIHCAFHNSHQELTRVLLSHGANMHLKNKSGHNAYQISQSMNNTNITLVMEE 1030
G +AL + D + ++ +++ GC+V+ D + WTPL+R++ A +GN ++ LL+ GAN+N +D G + L+ A N+H+EL ++LL GA+ +KN+ G ++++ + ++ ++EE
Sbjct: 210 GCTALHWAADGGHCSVIEWMIKDGCEVDVVDTGSGWTPLMRVS--AVSGNQRVASLLIDAGANVNVKDRNGKTPLM-VAVLNNHEELVQLLLDKGADASVKNEFGKGVLEMARVFDRQSVVSLLEE 332
BLAST of Fibronectin type III and ankyrin repeat domains 1 vs. UniProt/SwissProt
Match: sp|Q6B858|FANK1_BOVIN (Fibronectin type 3 and ankyrin repeat domains protein 1 OS=Bos taurus OX=9913 GN=FANK1 PE=2 SV=2) HSP 1 Score: 107.457 bits (267), Expect = 1.983e-39 Identity = 62/209 (29.67%), Postives = 117/209 (55.98%), Query Frame = 3
Query: 18 IQITLLMSNTKIPPKIPAPAVEIVNHHMLSISWSDINKRLSLILSEEE-AKCLAEISFKKINNFDEPWIVKGYADSCELEDFDQDSVYNYRIRLRNKNGWGEYSDEKSVHFPKEPVTGDDLHRAIIMNDEQLLLKLLQSGKINMNIPDRYDYTPLMACAIRNLEGLFACLVEYKVELDVQNKAGKTALMLAANKGNSRMVQLLLNHGAN 641
+++ + S++K P P V V HH + + W D+ K+ +E+ + E K++ + I GYA +E + ++Y +R+++ + +G YS SV +EP++ + LHRA+ +NDE LL+++LQ G + +++P+++ +T LM A R L L+ + ++++QN +GK +LMLA G+ +V+ L HGA+
Sbjct: 1 MELQKIASSSKPHP----PVVGKVTHHSIELYW-DLEKKAKRQGPQEQWFRFSIEEEDPKLHTYG--IIYTGYATKHVVEGLEPRTLYRFRLKVTSPSGEYAYSPVVSVSTTREPISSEHLHRAVNVNDEDLLVRILQGGNVKVDVPNKFGFTALMVAAQRGYTRLVKILISHGTDVNLQNGSGKDSLMLACYAGHLDVVKYLRRHGAS 202 HSP 2 Score: 77.7962 bits (190), Expect = 1.983e-39 Identity = 39/126 (30.95%), Postives = 76/126 (60.32%), Query Frame = 2
Query: 653 GMSALFYGVDNENIIIVRMLLEAGCDVNDTDKENEWTPLIRLAVLANNGNSKLGILLLQHGANINKQDTFGNSALIHCAFHNSHQELTRVLLSHGANMHLKNKSGHNAYQISQSMNNTNITLVMEE 1030
G +AL + D + ++ ++ GC+V+ D + WTPL+R++ A +GN ++ LL+ GA++N +D G + L+ A N+H+EL ++LL GA+ +KN+ G ++++ + N+ ++EE
Sbjct: 210 GCTALHWAADGGHCNVIEWMIGDGCEVDAVDAGSRWTPLMRVS--AVSGNQEVASLLIDAGADVNVKDKDGKTPLM-VAVLNNHEELVQLLLDRGADASVKNEFGKGVLEMARVFDRQNVLSLLEE 332
BLAST of Fibronectin type III and ankyrin repeat domains 1 vs. UniProt/SwissProt
Match: sp|Q66H07|FANK1_RAT (Fibronectin type 3 and ankyrin repeat domains 1 protein OS=Rattus norvegicus OX=10116 GN=Fank1 PE=2 SV=1) HSP 1 Score: 105.145 bits (261), Expect = 1.632e-38 Identity = 59/191 (30.89%), Postives = 108/191 (56.54%), Query Frame = 3
Query: 72 PAVEIVNHHMLSISWSDINKRLSLILSEEE-AKCLAEISFKKINNFDEPWIVKGYADSCELEDFDQDSVYNYRIRLRNKNGWGEYSDEKSVHFPKEPVTGDDLHRAIIMNDEQLLLKLLQSGKINMNIPDRYDYTPLMACAIRNLEGLFACLVEYKVELDVQNKAGKTALMLAANKGNSRMVQLLLNHGAN 641
P V V HH + + W D+ KR +E+ + E K++N+ I GYA +E + ++Y +R+++ + +G EYS SV +EP++ + HRA+ +NDE LLL++L+ G + +++P+++ +T LM A + L L+ +++++N +GK +LMLA G+ +V+ L HGA+
Sbjct: 15 PVVGKVTHHSIELYW-DLEKREKRQGPQEQWLRFSIEEEDPKMHNYGV--IYTGYATKHVVEGLEPRTLYRFRLKVTSPSGEYEYSPVVSVATTREPISSEHFHRAVNVNDEDLLLRILEGGHVMVDVPNKFGFTALMVAAQKGYTRLVKILISNGTDVNLKNGSGKDSLMLACYAGHLDVVKYLRKHGAS 202 HSP 2 Score: 77.0258 bits (188), Expect = 1.632e-38 Identity = 38/126 (30.16%), Postives = 77/126 (61.11%), Query Frame = 2
Query: 653 GMSALFYGVDNENIIIVRMLLEAGCDVNDTDKENEWTPLIRLAVLANNGNSKLGILLLQHGANINKQDTFGNSALIHCAFHNSHQELTRVLLSHGANMHLKNKSGHNAYQISQSMNNTNITLVMEE 1030
G +AL + D + ++ +++ GC+V+ D + WTPL+R++ A G+ K+ LL++ GA++N +D G + L+ A N+H++L ++LL GA+ +KN+ G ++++ + N+ ++EE
Sbjct: 210 GCTALHWAADGGHCPVIDWMIKDGCEVDVVDTGSGWTPLMRVS--AVTGSQKVASLLIEAGADVNVRDKDGKTPLM-VAVLNNHEQLVQLLLDKGADATVKNEFGKGVLEMARVFDRQNVLSLLEE 332
BLAST of Fibronectin type III and ankyrin repeat domains 1 vs. UniProt/SwissProt
Match: sp|Q9DAM9|FANK1_MOUSE (Fibronectin type 3 and ankyrin repeat domains 1 protein OS=Mus musculus OX=10090 GN=Fank1 PE=1 SV=1) HSP 1 Score: 103.605 bits (257), Expect = 7.225e-38 Identity = 57/190 (30.00%), Postives = 104/190 (54.74%), Query Frame = 3
Query: 72 PAVEIVNHHMLSISWSDINKRLSLILSEEEAKCLAEISFKKINNFDEPWIVKGYADSCELEDFDQDSVYNYRIRLRNKNGWGEYSDEKSVHFPKEPVTGDDLHRAIIMNDEQLLLKLLQSGKINMNIPDRYDYTPLMACAIRNLEGLFACLVEYKVELDVQNKAGKTALMLAANKGNSRMVQLLLNHGAN 641
P V V HH + + W K E+ + E K++++ I GYA +E + ++Y +R+++ + +G EYS SV +EP++ + HRA+ +NDE LLL++L+ G + +++P+++ +T LM A + L LV +++++N +GK +LMLA G+ +V+ L HGA+
Sbjct: 15 PVVGKVTHHSIELYWDLEQKEKRQGPQEQWLRFSIEEEDPKMHSYGV--IYTGYATRHVVEGLEPRTLYKFRLKVTSPSGEYEYSPVVSVATTREPISSEHFHRAVSVNDEDLLLRILEGGHVMIDVPNKFGFTALMVAAQKGYTRLVKILVSNGTDVNLKNGSGKDSLMLACYAGHLDVVKYLRRHGAS 202 HSP 2 Score: 76.2554 bits (186), Expect = 7.225e-38 Identity = 38/126 (30.16%), Postives = 77/126 (61.11%), Query Frame = 2
Query: 653 GMSALFYGVDNENIIIVRMLLEAGCDVNDTDKENEWTPLIRLAVLANNGNSKLGILLLQHGANINKQDTFGNSALIHCAFHNSHQELTRVLLSHGANMHLKNKSGHNAYQISQSMNNTNITLVMEE 1030
G +AL + D + ++ +++ GC+V+ D + WTPL+R++ A G+ K+ LL++ GA++N +D G + L+ A N+H++L ++LL GA+ +KN+ G ++++ + N+ ++EE
Sbjct: 210 GCTALHWAADGGHCSVIDWMIKDGCEVDVVDTGSGWTPLMRVS--AVTGSQKVASLLIEAGADVNIKDKDGKTPLM-VAVLNNHEQLVQLLLDKGADATVKNEFGKGVLEMARVFDRQNVLSLLEE 332
BLAST of Fibronectin type III and ankyrin repeat domains 1 vs. UniProt/SwissProt
Match: sp|Q01484|ANK2_HUMAN (Ankyrin-2 OS=Homo sapiens OX=9606 GN=ANK2 PE=1 SV=4) HSP 1 Score: 51.9878 bits (123), Expect = 9.964e-15 Identity = 34/115 (29.57%), Postives = 57/115 (49.57%), Query Frame = 2
Query: 653 GMSALFYGVDNENIIIVRMLLEAGCDVNDTDKENEWTPLIRLAVLANNGNSKLGILLLQHGANINKQDTFGNSALIHCAFHNSHQELTRVLLSHGANMHLKNKSGHNAYQISQSM 997
G+++L + + + +L + G D D + +TPLI V + GN K+ LL+ GAN+N + G + L H A H + VLL HGA + +G+ A I++ +
Sbjct: 695 GLTSLHLAAQEDKVNVADILTKHGAD-QDAHTKLGYTPLI---VACHYGNVKMVNFLLKQGANVNAKTKNGYTPL-HQAAQQGHTHIINVLLQHGAKPNATTANGNTALAIAKRL 804 HSP 2 Score: 50.0618 bits (118), Expect = 9.964e-15 Identity = 31/89 (34.83%), Postives = 51/89 (57.30%), Query Frame = 3
Query: 375 LHRAIIMNDEQLLLKLLQSGKINMNIPDRYDYTPLMACAIRNLEGLFACLVEYKVELDVQNKAGKTALMLAANKGNSRMVQLLLNHGAN 641
LH A +++++ L LL+ G + + + YTPL A +N + + L+ Y E ++ K G T L LA+ +G++ MV LLL+ GAN
Sbjct: 600 LHVAAHYDNQKVALLLLEKGA-SPHATAKNGYTPLHIAAKKNQMQIASTLLNYGAETNIVTKQGVTPLHLASQEGHTDMVTLLLDKGAN 687 HSP 3 Score: 41.9726 bits (97), Expect = 1.113e-6 Identity = 30/125 (24.00%), Postives = 59/125 (47.20%), Query Frame = 2
Query: 650 KGMSALFYGVDNENIIIVRMLLEAGCDVNDTDKENEWTPLIRLAVLANNGNSKLGILLLQHGANINKQDTFGNSALIHCAFHNSHQELTRVLLSHGANMHLKNKSGHNAYQISQSMNNTNITLVM 1024
+G++ L + +V +LL+ G +++ + K L L + A + +L +HGA+ + G + LI A H + ++ LL GAN++ K K+G+ + +T+I V+
Sbjct: 661 QGVTPLHLASQEGHTDMVTLLLDKGANIHMSTKSG----LTSLHLAAQEDKVNVADILTKHGADQDAHTKLGYTPLI-VACHYGNVKMVNFLLKQGANVNAKTKNGYTPLHQAAQQGHTHIINVL 780 HSP 4 Score: 32.3426 bits (72), Expect = 1.113e-6 Identity = 22/75 (29.33%), Postives = 38/75 (50.67%), Query Frame = 3
Query: 420 LLQSGKINMNIPDRYDYTPLMACAIRNLEGLFACLVEYKVELDVQNKAGKTALMLAANKGNSRMVQLLLNHGANP 644
LL++G + ++ + +TPL A + L++ + D K G T L +AA+ N ++ LLL GA+P
Sbjct: 549 LLEAGAAH-SLATKKGFTPLHVAAKYGSLDVAKLLLQRRAAADSAGKNGLTPLHVAAHYDNQKVALLLLEKGASP 622
BLAST of Fibronectin type III and ankyrin repeat domains 1 vs. TrEMBL
Match: A0A5J4NI57 (ANK_REP_REGION domain-containing protein OS=Paragonimus westermani OX=34504 GN=DEA37_0006106 PE=4 SV=1) HSP 1 Score: 138.658 bits (348), Expect = 8.849e-64 Identity = 63/127 (49.61%), Postives = 92/127 (72.44%), Query Frame = 2
Query: 653 GMSALFYGVDNENIIIVRMLLEAGCDVNDTDKENEWTPLIRLAVLANNGNSKLGILLLQHGANINKQDTFGNSALIHCAFHNSHQELTRVLLSHGANMHLKNKSGHNAYQISQSMNNTNITLVMEEF 1033
GM A+FY VD EN ++R+L + G V+ TD++N+WTPLIRLA LANNGN ++G L+ GAN+N QD +G +ALIHCAFH +H +L ++L+S GA+ ++NK H A I++S+ N N ++E+F
Sbjct: 210 GMHAVFYAVDGENGNMIRLLHKYGAKVDLTDRDNQWTPLIRLACLANNGNPRVGAALIDCGANVNHQDKYGQTALIHCAFHRNHTDLAKLLISCGADPVVRNKRNHTALDIARSLENLNFCALIEKF 336 HSP 2 Score: 135.576 bits (340), Expect = 8.849e-64 Identity = 69/201 (34.33%), Postives = 115/201 (57.21%), Query Frame = 3
Query: 60 KIPAPAVEIV--NHHMLSISWSDINKRLSLILSEEEAKCLAEISFKKINNFDEPWIVKGYADSCELEDFDQDSVYNYRIRLRNKNGWGEYSDEKSVHFPKEPVTGDDLHRAIIMNDEQLLLKLLQSGKINMNIPDRYDYTPLMACAIRNLEGLFACLVEYKVELDVQNKAGKTALMLAANKGNSRMVQLLLNHGANPLLKE 656
++ AP I + H L + W D + L ++ +C E+S +K+ + I G +D C + Y R+RL + +G Y +E++V P EP TG DLH+AI D + +L++G++N+ + D++D+TPLMA A RNL L++Y +++ NK GKTALM+AANKG + + + LL +GA+P +++
Sbjct: 11 RLTAPFAMITTPDFHTLKVEWFDSVEELEMM----GIRCAVEVSIRKLEYANWEVIYLGRSDKCTYNKMEPGLEYAVRLRLNVGDHFGPYGEEQTVEMPPEPNTGSDLHKAIKFEDMDQMRSILETGQVNLEVTDQFDFTPLMAVATRNLRNFVTVLLKYGAKVNTTNKLGKTALMIAANKGFTEIAEALLQNGADPNVQD 207
BLAST of Fibronectin type III and ankyrin repeat domains 1 vs. TrEMBL
Match: A0A4S2LXW8 (ANK_REP_REGION domain-containing protein OS=Opisthorchis felineus OX=147828 GN=CRM22_005531 PE=4 SV=1) HSP 1 Score: 137.502 bits (345), Expect = 4.887e-63 Identity = 62/127 (48.82%), Postives = 92/127 (72.44%), Query Frame = 2
Query: 653 GMSALFYGVDNENIIIVRMLLEAGCDVNDTDKENEWTPLIRLAVLANNGNSKLGILLLQHGANINKQDTFGNSALIHCAFHNSHQELTRVLLSHGANMHLKNKSGHNAYQISQSMNNTNITLVMEEF 1033
GM A+FY VD EN ++R+L + G +N D++N+WTPLIRLA LANNGN ++G L+ GAN+N +D +G +ALIHCAFH +H +L ++LLS GA+ ++NK H A+ I++S+ N N ++E+F
Sbjct: 204 GMHAVFYAVDGENGNMIRLLHKWGAHINLEDRDNQWTPLIRLACLANNGNPRVGSALIDCGANVNHRDKYGQTALIHCAFHRNHTDLAKLLLSSGADPDVRNKKNHTAWDIAKSLENLNFCQLVEKF 330 HSP 2 Score: 134.035 bits (336), Expect = 4.887e-63 Identity = 71/201 (35.32%), Postives = 113/201 (56.22%), Query Frame = 3
Query: 60 KIPAPAVEIV--NHHMLSISWSDINKRLSLILSEEEAKCLAEISFKKINNFDEPWIVKGYADSCELEDFDQDSVYNYRIRLRNKNGWGEYSDEKSVHFPKEPVTGDDLHRAIIMNDEQLLLKLLQSGKINMNIPDRYDYTPLMACAIRNLEGLFACLVEYKVELDVQNKAGKTALMLAANKGNSRMVQLLLNHGANPLLKE 656
+I AP I + H L + W D + L ++ KC E+S +K+++ + I G +D C + Y R+RL +G Y +E+ + P EP TG DLH+AI D L +L +G++N+ + D++D+TPLMA A RNL L+++ +++ NK GKTALM+AANKG + + LL +GA+P L++
Sbjct: 5 RITAPFAMITTPDFHTLKVEWFDSLEELEML----GLKCAVEVSIRKVDHSNWEVIYLGRSDQCSYSKMEPGMEYMVRLRLNMGEKFGPYGEEQPIEMPPEPNTGSDLHKAIKFEDMDQLRSILNAGQVNLEVADQFDFTPLMAVANRNLRNFVTVLIKHGAKVNTTNKLGKTALMIAANKGFIEIAECLLQNGADPNLQD 201
BLAST of Fibronectin type III and ankyrin repeat domains 1 vs. TrEMBL
Match: A0A504YL92 (Fibronectin type 3 and ankyrin repeat domain OS=Fasciola gigantica OX=46835 GN=FGIG_04085 PE=4 SV=1) HSP 1 Score: 135.576 bits (340), Expect = 2.766e-62 Identity = 61/127 (48.03%), Postives = 93/127 (73.23%), Query Frame = 2
Query: 653 GMSALFYGVDNENIIIVRMLLEAGCDVNDTDKENEWTPLIRLAVLANNGNSKLGILLLQHGANINKQDTFGNSALIHCAFHNSHQELTRVLLSHGANMHLKNKSGHNAYQISQSMNNTNITLVMEEF 1033
GM+A+FY VD E IVR+L+++G ++N D +N+WTPLIRLA LANNGN+++G L+ GA++N +D +G +AL+HCAFH +H +L ++LL+ GA+ +KNK H A I++S+ N +ME+F
Sbjct: 204 GMNAIFYAVDGEYGNIVRLLVKSGANINLEDHDNQWTPLIRLACLANNGNARVGAALIDCGADVNHRDKYGQTALMHCAFHRNHVDLAKLLLASGADPDIKNKKNHTALDIARSLENHGFCSMMEKF 330 HSP 2 Score: 134.035 bits (336), Expect = 2.766e-62 Identity = 71/193 (36.79%), Postives = 107/193 (55.44%), Query Frame = 3
Query: 66 PAPAVEIVNHHMLSISWSDINKRLSLILSEEEAKCLAEISFKKINNFDEPWIVKGYADSCELEDFDQDSVYNYRIRLRNKNGWGEYSDEKSVHFPKEPVTGDDLHRAIIMNDEQLLLKLLQSGKINMNIPDRYDYTPLMACAIRNLEGLFACLVEYKVELDVQNKAGKTALMLAANKGNSRMVQLLLNHGANP 644
P + + H L + W D L + KC E+S +K + + I G +D CE + Y R+RL + +G Y +E+ + P EP +G DLH+AI D + L +L +G++N+ DR D+TPLMA A RNL+ + L++Y + + NK GKTALM+AANKG + + + LLNHGA+P
Sbjct: 9 PFAMITTPDFHTLKVEWYDSLDELEM----AGLKCAVEVSIRKAEHSNWDVIYLGRSDHCEYNKMEPALEYFVRLRLTMDDQFGPYGEEQKIEMPPEPNSGSDLHKAIKYEDVEQLRAILDAGQVNIEATDRCDFTPLMAVASRNLKNMVHILIKYGAKPNTANKLGKTALMIAANKGYTEIAEYLLNHGADP 197
BLAST of Fibronectin type III and ankyrin repeat domains 1 vs. TrEMBL
Match: A0A075A3R2 (ANK_REP_REGION domain-containing protein OS=Opisthorchis viverrini OX=6198 GN=T265_00156 PE=4 SV=1) HSP 1 Score: 135.961 bits (341), Expect = 6.888e-62 Identity = 61/127 (48.03%), Postives = 92/127 (72.44%), Query Frame = 2
Query: 653 GMSALFYGVDNENIIIVRMLLEAGCDVNDTDKENEWTPLIRLAVLANNGNSKLGILLLQHGANINKQDTFGNSALIHCAFHNSHQELTRVLLSHGANMHLKNKSGHNAYQISQSMNNTNITLVMEEF 1033
GM A+FY VD EN ++R+L + G +N D++N+WTPLIRLA LANNGN ++G L+ GA++N +D +G +ALIHCAFH +H +L ++LLS GA+ ++NK H A+ I++S+ N N ++E+F
Sbjct: 204 GMHAVFYAVDGENGNMIRLLHKWGAHINLEDRDNQWTPLIRLACLANNGNPRVGSALIDCGADVNHRDKYGQTALIHCAFHRNHTDLAKLLLSCGADPDIRNKKNHTAWDIAKSLENLNFCQLVEKF 330 HSP 2 Score: 132.109 bits (331), Expect = 6.888e-62 Identity = 71/201 (35.32%), Postives = 112/201 (55.72%), Query Frame = 3
Query: 60 KIPAPAVEIV--NHHMLSISWSDINKRLSLILSEEEAKCLAEISFKKINNFDEPWIVKGYADSCELEDFDQDSVYNYRIRLRNKNGWGEYSDEKSVHFPKEPVTGDDLHRAIIMNDEQLLLKLLQSGKINMNIPDRYDYTPLMACAIRNLEGLFACLVEYKVELDVQNKAGKTALMLAANKGNSRMVQLLLNHGANPLLKE 656
+I AP I + H L + W D + L ++ KC E+S +K ++ + I G +D C + Y R+RL + +G Y +E+ + P EP TG DLH+AI D L +L G++++ + D++D+TPLMA A RNL L++Y +++ NK GKTALM+AANKG + + LL +GA+P L++
Sbjct: 5 RITAPFAMITTPDFHTLKVEWFDSLEELEML----GLKCAVEVSIRKTDHSNWEVIYLGRSDQCVYSKMEPGMEYMVRLRLNMGDKFGPYGEEQPIEMPPEPNTGSDLHKAIKFEDMDQLRSILSVGQVDLEVADQFDFTPLMAVANRNLRNFVTVLIKYGAKVNTTNKLGKTALMIAANKGFIEIAECLLQNGADPNLQD 201
BLAST of Fibronectin type III and ankyrin repeat domains 1 vs. TrEMBL
Match: A0A3R7CQN1 (Fibronectin type 3 and ankyrin repeat domains protein 1 OS=Clonorchis sinensis OX=79923 GN=FANK1 PE=4 SV=1) HSP 1 Score: 137.502 bits (345), Expect = 7.422e-62 Identity = 62/127 (48.82%), Postives = 92/127 (72.44%), Query Frame = 2
Query: 653 GMSALFYGVDNENIIIVRMLLEAGCDVNDTDKENEWTPLIRLAVLANNGNSKLGILLLQHGANINKQDTFGNSALIHCAFHNSHQELTRVLLSHGANMHLKNKSGHNAYQISQSMNNTNITLVMEEF 1033
GM A+FY VD EN ++R+L + G +N D++N+WTPLIRLA LANNGN ++G L+ GAN+N +D +G +ALIHCAFH +H +L ++LLS GA+ ++NK H A+ I++S+ N N ++E+F
Sbjct: 204 GMHAVFYAVDGENGNMIRLLHKWGAHINLEDRDNQWTPLIRLACLANNGNPRVGSALIDCGANVNHRDKYGQTALIHCAFHRNHTDLAKLLLSCGADPDIRNKKNHTAWDIAKSLENLNFCQLVEKF 330 HSP 2 Score: 130.183 bits (326), Expect = 7.422e-62 Identity = 71/201 (35.32%), Postives = 112/201 (55.72%), Query Frame = 3
Query: 60 KIPAPAVEIV--NHHMLSISWSDINKRLSLILSEEEAKCLAEISFKKINNFDEPWIVKGYADSCELEDFDQDSVYNYRIRLRNKNGWGEYSDEKSVHFPKEPVTGDDLHRAIIMNDEQLLLKLLQSGKINMNIPDRYDYTPLMACAIRNLEGLFACLVEYKVELDVQNKAGKTALMLAANKGNSRMVQLLLNHGANPLLKE 656
+I AP I + H L + W D + L ++ KC E+S +K ++ + I G +D C + Y R+RL ++ +G Y +E+ + P EP TG DLH+AI D L +L G++++ + D+ D+TPLMA A RNL L++Y +++ NK GKTALM+AANKG + + LL +GA+P L++
Sbjct: 5 RITAPFAMITTPDFHTLKVEWFDSLEELEML----GLKCAVEVSIRKADHSNWEVIYLGRSDQCTYPKMEPGMEYMVRLRLNMEDKFGPYGEEQPIEMPPEPNTGSDLHKAIKFEDMDQLRSILTVGQVDLEVADQSDFTPLMAVANRNLRNFVTVLIKYGAKVNTTNKLGKTALMIAANKGFIEIAECLLQNGADPNLQD 201
BLAST of Fibronectin type III and ankyrin repeat domains 1 vs. Ensembl Cavefish
Match: dapk1 (death-associated protein kinase 1 [Source:ZFIN;Acc:ZDB-GENE-060526-177]) HSP 1 Score: 49.6766 bits (117), Expect = 3.693e-12 Identity = 32/97 (32.99%), Postives = 52/97 (53.61%), Query Frame = 2
Query: 698 IVRMLLEAGCDVNDTDKENEWTPLIRLAVLANNGNSKLGILLLQHGANINKQDTFGNSALIHCAFHNSHQELTRVLLSHGANMHLKNKSGHNAYQIS 988
+ R L EAGCDVN ++E E +PL+ + G + LL+HGA+++ D G+ AL H A E+ + LLSH + +++ G+ I+
Sbjct: 491 VARALCEAGCDVNARNREGE-SPLLTASA---RGFRDIVECLLEHGADMDSTDKDGHIAL-HLAVRRCQIEVVKCLLSHHCYVDHQDRHGNTPLHIA 582 HSP 2 Score: 40.817 bits (94), Expect = 3.693e-12 Identity = 23/45 (51.11%), Postives = 30/45 (66.67%), Query Frame = 3
Query: 522 LVEYKVELDVQNKAGKTALMLAANKGNSRMVQLLLNHGANPLLKE 656
L E K LDVQ+K+G+TAL +AA GN +VQ L + ANP L +
Sbjct: 429 LHEKKCPLDVQDKSGETALHVAARYGNVDVVQYLCSIHANPDLTD 473
BLAST of Fibronectin type III and ankyrin repeat domains 1 vs. Ensembl Cavefish
Match: psmd10 (proteasome 26S subunit, non-ATPase 10 [Source:NCBI gene;Acc:103037594]) HSP 1 Score: 65.0846 bits (157), Expect = 4.968e-12 Identity = 43/113 (38.05%), Postives = 61/113 (53.98%), Query Frame = 2
Query: 653 GMSALFYGVDNENIIIVRMLLEAGCDVNDTDKENEWTPLIRLAVLANNGNSKLGILLLQHGANINKQDTFGNSALIHCAFHNSHQELTRVLLSHGANMHLKNKSGHNAYQISQ 991
G + L Y I +LLE G D N TDK E TPL R + GN +L LLL+ A+ N QD+ GN+AL H A E ++L+ HGA+++++NK QI++
Sbjct: 73 GCTPLHYAASKNQYEIALLLLENGADPNATDK-LESTPLHRASA---KGNYRLIQLLLKQSASTNIQDSEGNTAL-HLACDEERVEAAKLLVEHGASIYIENKEEKTPLQIAK 180
BLAST of Fibronectin type III and ankyrin repeat domains 1 vs. Ensembl Cavefish
Match: psmd10 (proteasome 26S subunit, non-ATPase 10 [Source:NCBI gene;Acc:103037594]) HSP 1 Score: 64.6994 bits (156), Expect = 1.314e-11 Identity = 43/113 (38.05%), Postives = 61/113 (53.98%), Query Frame = 2
Query: 653 GMSALFYGVDNENIIIVRMLLEAGCDVNDTDKENEWTPLIRLAVLANNGNSKLGILLLQHGANINKQDTFGNSALIHCAFHNSHQELTRVLLSHGANMHLKNKSGHNAYQISQ 991
G + L Y I +LLE G D N TDK E TPL R + GN +L LLL+ A+ N QD+ GN+AL H A E ++L+ HGA+++++NK QI++
Sbjct: 120 GCTPLHYAASKNQYEIALLLLENGADPNATDKL-ESTPLHRASA---KGNYRLIQLLLKQSASTNIQDSEGNTAL-HLACDEERVEAAKLLVEHGASIYIENKEEKTPLQIAK 227
BLAST of Fibronectin type III and ankyrin repeat domains 1 vs. Ensembl Cavefish
Match: psmd10 (proteasome 26S subunit, non-ATPase 10 [Source:NCBI gene;Acc:103037594]) HSP 1 Score: 64.3142 bits (155), Expect = 1.435e-11 Identity = 43/113 (38.05%), Postives = 61/113 (53.98%), Query Frame = 2
Query: 653 GMSALFYGVDNENIIIVRMLLEAGCDVNDTDKENEWTPLIRLAVLANNGNSKLGILLLQHGANINKQDTFGNSALIHCAFHNSHQELTRVLLSHGANMHLKNKSGHNAYQISQ 991
G + L Y I +LLE G D N TDK E TPL R + GN +L LLL+ A+ N QD+ GN+AL H A E ++L+ HGA+++++NK QI++
Sbjct: 106 GCTPLHYAASKNQYEIALLLLENGADPNATDK-LESTPLHRASA---KGNYRLIQLLLKQSASTNIQDSEGNTAL-HLACDEERVEAAKLLVEHGASIYIENKEEKTPLQIAK 213
BLAST of Fibronectin type III and ankyrin repeat domains 1 vs. Ensembl Cavefish
Match: ank1b (ankyrin 1, erythrocytic b [Source:ZFIN;Acc:ZDB-GENE-091113-6]) HSP 1 Score: 51.2174 bits (121), Expect = 1.640e-11 Identity = 37/105 (35.24%), Postives = 52/105 (49.52%), Query Frame = 2
Query: 653 GMSALFYGVDNENIIIVRMLLEAGCDVNDTDKENEWTPLIRLAVLANNGNSKLGILLLQHGANINKQDTFGNSALIHCAFHNSHQELTRVLLSHGANMHLKNKSG 967
G + L EN+ + ++LL G +VN T K N TPL + A GN + LLL GA I+ + T +HCA N H + +LL GA + K K+G
Sbjct: 181 GFTPLHIAAHYENLSVAQLLLNRGANVNFTPK-NGITPL---HIAARRGNVIMVRLLLDRGAQIDAR-TKDELTPLHCAARNGHVRVIEILLDQGAPIQAKTKNG 280 HSP 2 Score: 36.965 bits (84), Expect = 1.640e-11 Identity = 24/87 (27.59%), Postives = 44/87 (50.57%), Query Frame = 3
Query: 375 LHRAIIMNDEQLLLKLLQSGKINMNIPDRYDYTPLMACAIRNLEGLFACLVEYKVELDVQNKAGKTALMLAANKGNSRMVQLLLNHG 635
LH A + E+++ +L+ G N+N + ++PL A N + L+E + + G T L +A +G+ +V LL+N+G
Sbjct: 57 LHIAALAGQEKVVAELVHYGA-NVNAQSQKGFSPLYMAAQENHLEVVKFLLENGANQSLPTEDGFTPLAVALQQGHENVVALLINYG 142 HSP 3 Score: 41.2022 bits (95), Expect = 1.391e-7 Identity = 43/192 (22.40%), Postives = 80/192 (41.67%), Query Frame = 2
Query: 650 KGMSALFYGVDNENIIIVRMLLEAGCDVNDTDKENEWTPL-----------------------IRLAVL---ANNGNSKLGILLLQHGANINKQDTFGNSALIHCAFHNSHQELTRVLLSHGANMHLKNKSGHNAYQISQSMNNTNITLVM-----------EEFLNPSHCSNEN**IFHSKIVKIYTSENS 1114
KG S L+ ++ +V+ LLE G + E+ +TPL +RL L A N +++ +LLQ+ N + G + L H A H + + ++LL+ GAN++ K+G I+ N + ++ ++ L P HC+ N H ++++I + +
Sbjct: 85 KGFSPLYMAAQENHLEVVKFLLENGAN-QSLPTEDGFTPLAVALQQGHENVVALLINYGTKGKVRLPALHIAARNDDTRTAAVLLQNDPNPDVLSKTGFTPL-HIAAHYENLSVAQLLLNRGANVNFTPKNGITPLHIAARRGNVIMVRLLLDRGAQIDARTKDELTPLHCAARN---GHVRVIEILLDQGA 271 HSP 4 Score: 33.4982 bits (75), Expect = 1.391e-7 Identity = 15/40 (37.50%), Postives = 26/40 (65.00%), Query Frame = 3
Query: 522 LVEYKVELDVQNKAGKTALMLAANKGNSRMVQLLLNHGAN 641
L+ + ++L+ K G TAL +AA G ++V L+++GAN
Sbjct: 39 LLHHGIDLETTTKKGNTALHIAALAGQEKVVAELVHYGAN 78 HSP 5 Score: 44.669 bits (104), Expect = 8.780e-6 Identity = 34/124 (27.42%), Postives = 61/124 (49.19%), Query Frame = 2
Query: 653 GMSALFYGVDNENIIIVRMLLEAGCDVNDTDKENEWTPLIRLAVLANNGNSKLGILLLQHGANINKQDTFGNSALIHCAFHNSHQELTRVLLSHGANMHLKNKSGHNAYQISQSMNNTNITLVM 1024
G++ L ++ IV+ LL+ G N ++ + E TPL + A G+ ++ LLQ+ A ++ + + L HCA H+EL ++LL H AN +GH I+ + + T ++
Sbjct: 379 GLTPLHVAAFMGHLNIVKSLLQRGASPNASNVKVE-TPL---HMAARAGHCEVAQFLLQNLAQVDAKAKDDQTPL-HCAARMGHKELVKLLLEHKANPDSATTAGHTPLHIAAREGHAHTTRIL 497 HSP 6 Score: 23.8682 bits (50), Expect = 8.780e-6 Identity = 17/42 (40.48%), Postives = 21/42 (50.00%), Query Frame = 3
Query: 534 KVELDVQNKA------GKTALMLAANKGNSRMVQLLLNHGAN 641
KV LD KA G T L +A K + R + LLL H A+
Sbjct: 330 KVLLDKGAKANARALNGFTPLHIACKKNHMRSMDLLLKHSAS 371
BLAST of Fibronectin type III and ankyrin repeat domains 1 vs. Ensembl Sea Lamprey
Match: BCL3 (BCL3 transcription coactivator [Source:HGNC Symbol;Acc:HGNC:998]) HSP 1 Score: 63.929 bits (154), Expect = 2.434e-16 Identity = 42/114 (36.84%), Postives = 63/114 (55.26%), Query Frame = 2
Query: 647 FKGMSALFYGVDNENIIIVRMLLEAGCDVNDTDKENEWTPLIRLAVLANNGNSKLGILLLQHGANINKQDTFGNSALIHCAFHNSHQELTRVLLSHGANMHLKNKSGHNAYQIS 988
F GM+ L V + V LLE +V+ D +N + LI N N ++ LL++HGAN+N+Q T+G +A +H A E+T +L+ HGAN+ LKN NAY ++
Sbjct: 127 FSGMTPLHVAVKGSCVSAVSRLLENQVNVDALDWKNGSSALIYAV---ENDNIEIVELLIKHGANVNQQ-TYGGNAAVHVASGRGLLEITHLLVRHGANVGLKNTQNDNAYTVT 236 HSP 2 Score: 38.1206 bits (87), Expect = 2.434e-16 Identity = 23/87 (26.44%), Postives = 45/87 (51.72%), Query Frame = 3
Query: 375 LHRAIIMNDEQLLLKLLQ---SGKINMNIPDRYDYTPLMACAIRNLEGLFACLVEYKVELDVQNKAGKTALMLAANKGNSRMVQLLL 626
LH A++ + Q++ K++Q G+I++++ + +PL I E L A L+ ++ G A+ LA + G + ++ LLL
Sbjct: 27 LHIAVVQQNVQMVNKIVQLFHMGRISLDVCNHLHQSPLHLAIITGQEALVAVLLSGGASPAALDRHGMNAVHLACSAGQTHVLALLL 113
BLAST of Fibronectin type III and ankyrin repeat domains 1 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000003991.1 (pep scaffold:Pmarinus_7.0:GL484476:255315:281660:1 gene:ENSPMAG00000003623.1 transcript:ENSPMAT00000003991.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 46.595 bits (109), Expect = 2.125e-13 Identity = 30/83 (36.14%), Postives = 43/83 (51.81%), Query Frame = 3
Query: 408 LLLKLLQSGKINMNIPDRYDYTPLMACAIRNLEGLFACLVEYKVELDVQNKAGKTALMLAANKGNSRMVQLLLNHGANPLLKE 656
L L L Q G + + +PL A G L+ V+LDV+ G T L LAA +G++ V++L+ HGA+ LLKE
Sbjct: 564 LELLLEQPGAFQSDGKSGHPISPLHLAAYHGHHGALEVLIRSLVDLDVREGNGYTPLGLAALRGHTDCVRVLIQHGASVLLKE 646 HSP 2 Score: 45.8246 bits (107), Expect = 2.125e-13 Identity = 37/121 (30.58%), Postives = 60/121 (49.59%), Query Frame = 2
Query: 659 SALFYGVDNENIIIVRMLLEAGCDVN---DTDKENEWTPLIRLAVLANNGNSKLGILLLQHGANINKQDTFGNSALIHCAFHNSHQELTRVLLSHGANMHLKNKSGHNAYQISQSMNNTNI 1012
+AL N ++ +R+L+E D N D NE TP++ LAV NG++ LLL GA+IN +D G +AL H H+E +LL ++ L+ + G ++ + + I
Sbjct: 652 TALHSAATNGHVECLRLLVE-NADSNEAVDASDANEQTPVM-LAV--GNGHTDCASLLLSKGASINAKDNKGCTAL-HRGAATGHEECVDLLLQRSVDVSLRERRGRAPLHMAAACGHMGI 767 HSP 3 Score: 40.4318 bits (93), Expect = 5.622e-9 Identity = 29/89 (32.58%), Postives = 42/89 (47.19%), Query Frame = 3
Query: 375 LHRAIIMNDEQLLLKLLQSGKINMNIPDRYDYTPLMACAIRNLEGLFACLVEYKVELDVQNKAGKTALMLAANKGNSRMVQLLLNHGAN 641
LHRA E + LL+ ++N D+ TPL A ++ +V ++AG+TAL AA G+S MV L+ GAN
Sbjct: 76 LHRACASRSEAAVQTLLKH-SADVNARDKNWQTPLHVAAANRAVKCAEAIIPMLSSSNVSDRAGRTALHHAAFNGHSEMVNFLVAKGAN 163 HSP 4 Score: 36.965 bits (84), Expect = 5.622e-9 Identity = 31/114 (27.19%), Postives = 60/114 (52.63%), Query Frame = 2
Query: 650 KGMSALFYGVDNENIIIVRMLLEAGCDVNDTDKENEWTPLIRLAVLANNGNSKLGILLLQHGANINKQDTFGNSALIHCAFHNSHQELT-RVLLSHGANMHLKNKSGHNAYQIS 988
KG S L + I +V++LL+ G D++D + L V NG + L+ GAN+N+ + G + L H A ++H L +L+++GA++++++K G + ++
Sbjct: 203 KGYSPLHAASSSGQIGVVKLLLDLGVDIDDPNSFGNTA----LHVACYNGQDVVVNELIDCGANVNQANERGFTPL-HFAAASTHGALCLELLVNNGADVNVQSKDGKSPLHMT 311 HSP 5 Score: 38.891 bits (89), Expect = 1.028e-7 Identity = 26/89 (29.21%), Postives = 46/89 (51.69%), Query Frame = 3
Query: 375 LHRAIIMNDEQLLLKLLQSGKINMNIPDRYDYTPLMACAIRNLEGLFACLVEYKVELDVQNKAGKTALMLAANKGNSRMVQLLLNHGAN 641
+H A M +++ K+L + ++ D+ Y+PL A + G+ L++ V++D N G TAL +A G +V L++ GAN
Sbjct: 175 IHWAAYMGHTEVV-KVLVAHGADVRCKDKKGYSPLHAASSSGQIGVVKLLLDLGVDIDDPNSFGNTALHVACYNGQDVVVNELIDCGAN 262 HSP 6 Score: 33.8834 bits (76), Expect = 1.028e-7 Identity = 29/99 (29.29%), Postives = 49/99 (49.49%), Query Frame = 2
Query: 650 KGMSAL-FYGVDNENIIIVRMLLEAGCDVNDTDKENEWTPLIRLAVLANNGNSKLGILLLQHGANINKQDTFGNSALIHCAFHNSHQELTRVLLSHGAN 943
+G + L F + + +L+ G DVN K+ + +PL AV +G L+Q+G I+ +D GN+ L H A H+ L L+++GA+
Sbjct: 269 RGFTPLHFAAASTHGALCLELLVNNGADVNVQSKDGK-SPLHMTAV---HGRFTRSQTLIQNGGEIDCEDRDGNTPL-HIAARYGHELLINTLITNGAD 362
BLAST of Fibronectin type III and ankyrin repeat domains 1 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000007446.1 (pep scaffold:Pmarinus_7.0:GL478728:200023:240674:1 gene:ENSPMAG00000006704.1 transcript:ENSPMAT00000007446.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 53.1434 bits (126), Expect = 4.297e-12 Identity = 41/139 (29.50%), Postives = 68/139 (48.92%), Query Frame = 2
Query: 653 GMSALFYGVDNENIIIVRMLLEAGCDVNDTDKENEWTPLIRLAVLANNGNSKLGILLLQHGANINKQDTFGNSALIHCAFHNSHQELTRVLLSHGANMHLKNKSGHNAYQISQSMNNTNIT----LVMEEFLNPSHCSN 1057
G+S L + + + +L++ G VN T K +TPLI V + GN K+ LLQHGA++N + G + L H A H + +LL GA + +G+ A I++ + ++ +V EE + + SN
Sbjct: 402 GLSPLHLAAQEDKVNVAEILVKHGAHVNATTKLG-YTPLI---VACHYGNIKMVNFLLQHGADVNSKTKNGYTPL-HQAAQQGHTHIVNLLLKCGARPNDVTVNGNTALAIARRLGYISVVDTLKVVTEETITSTTVSN 535 HSP 2 Score: 34.2686 bits (77), Expect = 4.297e-12 Identity = 25/89 (28.09%), Postives = 44/89 (49.44%), Query Frame = 3
Query: 375 LHRAIIMNDEQLLLKLLQSGKINMNIPDRYDYTPLMACAIRNLEGLFACLVEYKVELDVQNKAGKTALMLAANKGNSRMVQLLLNHGAN 641
LH A +++++ L LL G + + + YTPL A ++ + L+EY E + + G L L A +G++ + LLL A+
Sbjct: 307 LHVASHYDNQKVALLLLDQGA-SPHATAKNGYTPLHIAAKKDQLEIATTLLEYGAETNAITRQGVAPLHLGAQEGHADVASLLLARYAD 394 HSP 3 Score: 52.7582 bits (125), Expect = 5.720e-9 Identity = 38/132 (28.79%), Postives = 65/132 (49.24%), Query Frame = 2
Query: 650 KGMSALFYGVDNENIIIVRMLLEAGCDVNDTDKENEWTPLIRLAVLANNGNSKLGILLLQHGANINKQDTFGNSALIHCAFHNSHQELTRVLLSHGANMHLKNKSGHNAYQISQSMNNTNI-TLVMEEFLNP 1042
+G +AL +VR LL G V+ +E E TPL + A G ++ LLLQH A+ + + G + L H A H+++T +LL HGA++ + K G ++ + +L+++ F +P
Sbjct: 170 RGETALHMAARAGQTEVVRSLLRNGAQVDAKARE-EQTPL---HIAARLGKLEIVQLLLQHMASPDAATSNGYTPL-HVAAREGHEDVTAILLEHGASLAVTTKKGFTPLHVASKYGKMEVASLLLQRFASP 296 HSP 4 Score: 24.2534 bits (51), Expect = 5.720e-9 Identity = 12/32 (37.50%), Postives = 20/32 (62.50%), Query Frame = 3
Query: 546 DVQNKAGKTALMLAANKGNSRMVQLLLNHGAN 641
+V+ G T L +A K R+++LLL +GA+
Sbjct: 99 NVRALNGFTPLHIACKKNRIRVMELLLKYGAS 130
BLAST of Fibronectin type III and ankyrin repeat domains 1 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000007449.1 (pep scaffold:Pmarinus_7.0:GL478728:201453:233342:1 gene:ENSPMAG00000006704.1 transcript:ENSPMAT00000007449.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 50.447 bits (119), Expect = 2.309e-11 Identity = 41/141 (29.08%), Postives = 69/141 (48.94%), Query Frame = 2
Query: 653 GMSALFYGVDNENIIIVRMLLEAGCDVNDTDKENEWTPLIRLAVLANNGNSKLGILLLQHGANINKQDTFGNSALIHCAFHNSHQELTRVLLSHGANMHLKNKSGHNAYQISQSMNNTNIT----LVMEEFLNPSHCSNEN 1063
G+S L + + + +L++ G VN T K +TPLI V + GN K+ LLQHGA++N + G + L H A H + +LL GA + +G+ A I++ + ++ +V EE + + SN +
Sbjct: 312 GLSPLHLAAQEDKVNVAEILVKHGAHVNATTKLG-YTPLI---VACHYGNIKMVNFLLQHGADVNSKTKNGYTPL-HQAAQQGHTHIVNLLLKCGARPNDVTVNGNTALAIARRLGYISVVDTLKVVTEETITSTTVSNPS 447 HSP 2 Score: 34.6538 bits (78), Expect = 2.309e-11 Identity = 24/84 (28.57%), Postives = 42/84 (50.00%), Query Frame = 3
Query: 375 LHRAIIMNDEQLLLKLLQSGKINMNIPDRYDYTPLMACAIRNLEGLFACLVEYKVELDVQNKAGKTALMLAANKGNSRMVQLLL 626
LH A +++++ L LL G + + + YTPL A ++ + L+EY E + + G L L A +G++ + LLL
Sbjct: 217 LHVASHYDNQKVALLLLDQGA-SPHATAKNGYTPLHIAAKKDQLEIATTLLEYGAETNAITRQGVAPLHLGAQEGHADVASLLL 299 HSP 3 Score: 55.0694 bits (131), Expect = 2.202e-9 Identity = 38/132 (28.79%), Postives = 65/132 (49.24%), Query Frame = 2
Query: 650 KGMSALFYGVDNENIIIVRMLLEAGCDVNDTDKENEWTPLIRLAVLANNGNSKLGILLLQHGANINKQDTFGNSALIHCAFHNSHQELTRVLLSHGANMHLKNKSGHNAYQISQSMNNTNI-TLVMEEFLNP 1042
+G +AL +VR LL G V+ +E E TPL + A G ++ LLLQH A+ + + G + L H A H+++T +LL HGA++ + K G ++ + +L+++ F +P
Sbjct: 80 RGETALHMAARAGQTEVVRSLLRNGAQVDAKARE-EQTPL---HIAARLGKLEIVQLLLQHMASPDAATSNGYTPL-HVAAREGHEDVTAILLEHGASLAVTTKKGFTPLHVASKYGKMEVASLLLQRFASP 206 HSP 4 Score: 23.0978 bits (48), Expect = 2.202e-9 Identity = 11/26 (42.31%), Postives = 17/26 (65.38%), Query Frame = 3
Query: 564 GKTALMLAANKGNSRMVQLLLNHGAN 641
G T L +A K R+++LLL +GA+
Sbjct: 15 GFTPLHIACKKNRIRVMELLLKYGAS 40
BLAST of Fibronectin type III and ankyrin repeat domains 1 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000009528.1 (pep scaffold:Pmarinus_7.0:GL478737:432:18044:-1 gene:ENSPMAG00000008612.1 transcript:ENSPMAT00000009528.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 39.2762 bits (90), Expect = 4.886e-9 Identity = 30/118 (25.42%), Postives = 62/118 (52.54%), Query Frame = 2
Query: 653 GMSALFYGVDNENIIIVRMLLEAGCDVNDTDKENEWTPLIRLAVLANNGNSKLGILLLQHGANINKQDTFGNSALIHCAFHNSHQELTRVLLSHGANMHLKNKSGHNAYQISQSMNNT 1006
G + + + + +++ +VR+LL G DV T ++NE + A A G+ + + +++ + G++ L H A +H E +LL+ GAN+ ++NK G + + S+++T
Sbjct: 665 GWTPVIWTAEYKHVDVVRLLLSRGADV--TLRDNEENICLHWAAFA--GSVDIAEEFINAQCDLHAANLHGDTPL-HIASRENHYECVVLLLARGANVDVRNKEGETPMECA-SVDST 776 HSP 2 Score: 38.1206 bits (87), Expect = 4.886e-9 Identity = 28/87 (32.18%), Postives = 44/87 (50.57%), Query Frame = 3
Query: 375 LHRAIIMNDEQLLLKLLQSGKINMNIPDRYDYTPLMACAIRNLEGLFACLVEYKVELDVQNKAGKTALMLAANKGNSRMVQLLLNHG 635
+H A ++L L+Q+G N++ D+ TPL+ A N LV+ + ++ G T L LAA KGN +VQ L++ G
Sbjct: 569 MHGAAERGHVEVLHTLVQAGG-NIDACDQDQKTPLLQAAESNQLASTRYLVKAGAYVAHKDDEGATCLHLAAKKGNLEVVQYLVSTG 654
BLAST of Fibronectin type III and ankyrin repeat domains 1 vs. Ensembl Yeast
Match: PHO81 (Cyclin-dependent kinase (CDK) inhibitor; regulates Pho80p-Pho85p and Pcl7p-Pho85p cyclin-CDK complexes in response to phosphate levels; inhibitory activity for Pho80p-Pho85p requires myo-D-inositol heptakisphosphate (IP7) generated by Vip1p; relative distribution to the nucleus increases upon DNA replication stress [Source:SGD;Acc:S000003465]) HSP 1 Score: 46.9802 bits (110), Expect = 3.907e-6 Identity = 29/106 (27.36%), Postives = 56/106 (52.83%), Query Frame = 2
Query: 698 IVRMLLEAGCDVNDTDKENEWTPLIRLAVLANNGNSKLGILLLQHGANINKQDTFGNSALIHCAFHNSHQELTRVLLSHGANMHLKNKSGHNAYQISQSMNNTNIT 1015
++++L+ G D N+ D N+WTP+ +G+S++ LL+H A ++ +D G+S L + A SH ++ LL N+ + N+ +Q +N ++T
Sbjct: 573 LIQLLIRYGADPNEIDGFNKWTPIF---YAVRSGHSEVITELLKHNARLDIEDDNGHSPLFY-ALWESHVDVLNALLQRPLNLPSAPLNEINSQSSTQRLNTIDLT 674
BLAST of Fibronectin type III and ankyrin repeat domains 1 vs. Ensembl Nematostella
Match: EDO49304 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RH71]) HSP 1 Score: 84.3445 bits (207), Expect = 9.081e-18 Identity = 54/206 (26.21%), Postives = 97/206 (47.09%), Query Frame = 3
Query: 21 QITLLMSNTKIPPKIPAPAVEIVNHHMLSISWSDINKRLSLILSEEEAKCLAEISFKKINNFDEPWIVKGYADSCELEDFDQDSVYNYRIRLRNKNGWGEYSDEKSVHFPKEPVTGDDLHRAIIMNDEQLLLKLL-QSGKINMNIPDRYDYTPLMACAIRNLEGLFACLVEYKVELDVQNKAGKTALMLAANKGNSRMVQLLLNHG 635
QI + P + P V+ V H + +SW C+ E K + + G+A + + ++ Y+YRIR+ N +G +S SV K P+TG D+H+AI+ + + + +L +S +N+PD Y +PLM + + + L+E +++ + +GKT+LMLA G+ ++ +L HG
Sbjct: 10 QIVFPNKDMAEPERPDPPCVDKVTHCSIELSWGGAGPEGDAKGDGRRKYCVQEEEEGKDREYGT--VYNGFAINHVFRGLEPNTTYHYRIRVSNNHGCSAWSASISVSTTKVPLTGQDIHKAIVNWEVEKVKHILDESDDSLVNVPDAYGMSPLMIASQKGYTSIVEILIERGADVNYVSGSGKTSLMLACFGGHLKVATILHEHG 213
BLAST of Fibronectin type III and ankyrin repeat domains 1 vs. Ensembl Nematostella
Match: EDO35910 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SK80]) HSP 1 Score: 62.003 bits (149), Expect = 2.579e-17 Identity = 44/200 (22.00%), Postives = 86/200 (43.00%), Query Frame = 3
Query: 63 IPAPAVEIVNHHMLSISWSDINKRLSLIL---SEEEAKCLAEISFKKINNFDEPWIVKGYADSCELEDFDQDSVYNYRIRLRNKN------GWGEYSDEKSVHFPKEPVTGDDLHRAIIMNDEQLLLKLLQSGKINMNIPDRYDYTPLMACAIRNLEGLFACLVEYKVELDVQNKAGKTALMLAANKGNSRMVQLLLNHG 635
P+ + V ++ + +SW + K L I + + + + N+ +GY +S + + ++ Y R R + + G +S V KEP +G +LH+A+ D + K+L + + D++ TPLM A + + L+E+ + + N +GKT +M++ G +LL G
Sbjct: 4 FPSITIGKVTYNSIEVSWENDKKTLHHIQISKARSSSPSPGAPALDPLTNY------QGYGNSHVFKSLEPNTEYLCRSRFVDGSQQTLGHGAARWSQPNHVFTAKEPPSGAELHKAVARQDLDQVRKILSENNSVVEVMDKFGLTPLMVAAQKGYIDVMETLLEFGADPNYFNSSGKTCMMISCYSGQEEPAKLLRERG 197 HSP 2 Score: 44.2838 bits (103), Expect = 2.579e-17 Identity = 21/68 (30.88%), Postives = 42/68 (61.76%), Query Frame = 2
Query: 653 GMSALFYGVDNENIIIVRMLLEAGCDVNDTDKENEWTPLIRLAVLANNGNSKLGILLLQHGANINKQD 856
G++++ + D + ++ +L+ G V+ D N WTPL+R+A L+ GN ++ +L+ GA++N+ D
Sbjct: 207 GLTSVHWAADGGHDDLLLWMLKDGAQVDLEDTYNGWTPLMRVACLS--GNDEVAEVLIAKGADVNRTD 272
BLAST of Fibronectin type III and ankyrin repeat domains 1 vs. Ensembl Nematostella
Match: EDO38454 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SCS9]) HSP 1 Score: 53.9138 bits (128), Expect = 4.555e-9 Identity = 40/116 (34.48%), Postives = 59/116 (50.86%), Query Frame = 2
Query: 653 GMSALFYGVDNENIIIVRMLLEAGCDVNDTDKENEWTPLIRLAVLANNGN----SKLGILLLQHGANINKQDTFGNSALIHCAFHNSHQELTRVLLSHGANMHLKNKSGHNAYQIS 988
G + + + +VRMLLE G + D N+ TPLI LA A+NGN KL L+++ A +N QDT G +AL+H S L + LL AN +++ + A+ S
Sbjct: 6 GAKEILRASRDLKLRLVRMLLEGGTQI-DVRSTNQETPLI-LAC-ASNGNQGEKEKLVKYLIRNRAKVNLQDTQGRTALMHACITTSPDNLIQALLDAKANPWIEDNARKTAFDYS 118
BLAST of Fibronectin type III and ankyrin repeat domains 1 vs. Ensembl Nematostella
Match: EDO47126 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RNE2]) HSP 1 Score: 48.521 bits (114), Expect = 2.610e-6 Identity = 29/77 (37.66%), Postives = 47/77 (61.04%), Query Frame = 3
Query: 420 LLQSGKINMNIPDRYDYTPLMACAIRNLEGLFACLVEYKVELDVQNKAGKTALMLAANKGNSRMVQLLLNHGANPLL 650
LL++G + DR+ TPLM A + L L+E ++D Q+ G TAL AA++G+ R+V++LL++ A+P L
Sbjct: 233 LLENG-ARTGVYDRHRITPLMYAARQGRVSLCKKLIEKGAQVDKQDVRGWTALSWAASEGHGRLVRVLLDYKADPQL 308
BLAST of Fibronectin type III and ankyrin repeat domains 1 vs. Ensembl Medaka
Match: psmd10 (proteasome 26S subunit, non-ATPase 10 [Source:NCBI gene;Acc:101166639]) HSP 1 Score: 70.8626 bits (172), Expect = 8.648e-14 Identity = 44/113 (38.94%), Postives = 61/113 (53.98%), Query Frame = 2
Query: 653 GMSALFYGVDNENIIIVRMLLEAGCDVNDTDKENEWTPLIRLAVLANNGNSKLGILLLQHGANINKQDTFGNSALIHCAFHNSHQELTRVLLSHGANMHLKNKSGHNAYQISQ 991
G + L Y + I MLLE G D N TDK EWTPL R + GN +L LLL+ A+ N QD GN+ L H A E ++L+ HGA+++++NK QI++
Sbjct: 106 GCTPLHYAASKDRYEIALMLLENGADPNATDKL-EWTPLHRASA---KGNYRLIQLLLKQSASTNIQDCQGNTPL-HLACEEERVEAAKLLVEHGASIYIENKEEKTPLQIAK 213
BLAST of Fibronectin type III and ankyrin repeat domains 1 vs. Ensembl Medaka
Match: ank1b (ankyrin-1 [Source:NCBI gene;Acc:101157380]) HSP 1 Score: 55.8398 bits (133), Expect = 1.658e-12 Identity = 38/105 (36.19%), Postives = 53/105 (50.48%), Query Frame = 2
Query: 653 GMSALFYGVDNENIIIVRMLLEAGCDVNDTDKENEWTPLIRLAVLANNGNSKLGILLLQHGANINKQDTFGNSALIHCAFHNSHQELTRVLLSHGANMHLKNKSG 967
G + L EN+ + ++LL G +VN T K N TPL + + GN + LLL GA I+ Q T +HCA N H + +LL HGA + K K+G
Sbjct: 204 GFTPLHIAAHYENMSVAQLLLNRGANVNFTPK-NGITPL---HIASRRGNVMMVRLLLDRGAQIDAQ-TKDELTPLHCAARNGHVRIIEILLEHGAPIQAKTKNG 303 HSP 2 Score: 35.4242 bits (80), Expect = 1.658e-12 Identity = 24/87 (27.59%), Postives = 43/87 (49.43%), Query Frame = 3
Query: 375 LHRAIIMNDEQLLLKLLQSGKINMNIPDRYDYTPLMACAIRNLEGLFACLVEYKVELDVQNKAGKTALMLAANKGNSRMVQLLLNHG 635
LH A + E+++ +L+ G N+N ++PL A N + L+E + + G T L +A +G+ +V LL+N+G
Sbjct: 80 LHIAALAGQEKVVAELVNYGA-NVNAQSHKGFSPLYMAAQENHLEVVKFLLENGANQSLPTEDGFTPLAVALQQGHENVVALLINYG 165 HSP 3 Score: 46.9802 bits (110), Expect = 4.791e-10 Identity = 32/98 (32.65%), Postives = 51/98 (52.04%), Query Frame = 2
Query: 653 GMSALFYGVDNENIIIVRMLLEAGCDVNDTDKENEWTPLIRLAVLANNGNSKLGILLLQHGANINKQDTFGNSALIHCAFHNSHQELTRVLLSHGANM 946
G++ L N+++VR+LL+ G + D ++E TPL A NG+ ++ +LL+HGA I + G S IH A H + R LL + A +
Sbjct: 237 GITPLHIASRRGNVMMVRLLLDRGAQI-DAQTKDELTPL---HCAARNGHVRIIEILLEHGAPIQAKTKNGLSP-IHMAAQGDHMDCVRQLLQYNAEI 329 HSP 4 Score: 36.1946 bits (82), Expect = 4.791e-10 Identity = 31/106 (29.25%), Postives = 43/106 (40.57%), Query Frame = 3
Query: 411 LLKLLQSGKINMNIPDRYDYTPLMACAIRNLEGLFACLVEY----KVEL-------------------------DVQNKAGKTALMLAANKGNSRMVQLLLNHGAN 641
++K L N ++P +TPL + E + A L+ Y KV L DV +K G T L +AA+ N + QLLLN GAN
Sbjct: 124 VVKFLLENGANQSLPTEDGFTPLAVALQQGHENVVALLINYGTKGKVRLPALHIAARNDDTRTAAVLLQNDPNPDVLSKTGFTPLHIAAHYENMSVAQLLLNRGAN 229 HSP 5 Score: 44.2838 bits (103), Expect = 4.137e-9 Identity = 44/186 (23.66%), Postives = 78/186 (41.94%), Query Frame = 2
Query: 650 KGMSALFYGVDNENIIIVRMLLEAGCDVNDTDKENEWTPL-----------------------IRLAVL---ANNGNSKLGILLLQHGANINKQDTFGNSALIHCAFHNSHQELTRVLLSHGANMHLKNKSGHNAYQISQSMNNTNITLVM-----------EEFLNPSHCSNEN**IFHSKIVKI 1096
KG S L+ ++ +V+ LLE G + E+ +TPL +RL L A N +++ +LLQ+ N + G + L H A H + + ++LL+ GAN++ K+G I+ N + ++ ++ L P HC+ N H +I++I
Sbjct: 108 KGFSPLYMAAQENHLEVVKFLLENGAN-QSLPTEDGFTPLAVALQQGHENVVALLINYGTKGKVRLPALHIAARNDDTRTAAVLLQNDPNPDVLSKTGFTPL-HIAAHYENMSVAQLLLNRGANVNFTPKNGITPLHIASRRGNVMMVRLLLDRGAQIDAQTKDELTPLHCAARN---GHVRIIEI 288 HSP 6 Score: 35.8094 bits (81), Expect = 4.137e-9 Identity = 22/68 (32.35%), Postives = 35/68 (51.47%), Query Frame = 3
Query: 438 INMNIPDRYDYTPLMACAIRNLEGLFACLVEYKVELDVQNKAGKTALMLAANKGNSRMVQLLLNHGAN 641
IN+NI ++ L + + L+ +EL+ K G TAL +AA G ++V L+N+GAN
Sbjct: 34 ININIANQNGLNGLHLASKEGHVKMVLELLHSGIELEATTKKGNTALHIAALAGQEKVVAELVNYGAN 101
BLAST of Fibronectin type III and ankyrin repeat domains 1 vs. Ensembl Medaka
Match: psmd10 (proteasome 26S subunit, non-ATPase 10 [Source:NCBI gene;Acc:101166639]) HSP 1 Score: 65.0846 bits (157), Expect = 3.927e-12 Identity = 41/98 (41.84%), Postives = 56/98 (57.14%), Query Frame = 2
Query: 698 IVRMLLEAGCDVNDTDKENEWTPLIRLAVLANNGNSKLGILLLQHGANINKQDTFGNSALIHCAFHNSHQELTRVLLSHGANMHLKNKSGHNAYQISQ 991
I MLLE G D N TDK EWTPL R + GN +L LLL+ A+ N QD GN+ L H A E ++L+ HGA+++++NK QI++
Sbjct: 80 IALMLLENGADPNATDK-LEWTPLHRASA---KGNYRLIQLLLKQSASTNIQDCQGNTPL-HLACEEERVEAAKLLVEHGASIYIENKEEKTPLQIAK 172
BLAST of Fibronectin type III and ankyrin repeat domains 1 vs. Ensembl Medaka
Match: ENSORLT00000005069.2 (serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit A [Source:NCBI gene;Acc:101168382]) HSP 1 Score: 44.2838 bits (103), Expect = 2.234e-11 Identity = 30/99 (30.30%), Postives = 57/99 (57.58%), Query Frame = 2
Query: 698 IVRMLLEAGCDVNDTDKENEWTPLIRLAVLANNGNSKLGILLLQHGANINKQDTFGNSALIHCAFHNSHQELTRVLLSHGANMHLKNKSGHNAYQISQS 994
+V++L+E+G +V+ DK+ ++P L A++G S LL G ++N+ +++GN+ L H A +N + L+ GAN++ N+ G +A + S
Sbjct: 231 VVKLLVESGAEVDCKDKKG-YSP---LHAAASSGMSSTVHYLLGLGVHVNEANSYGNTPL-HLACYNGQDVVVGELIQAGANVNQVNERGFSALHFASS 324 HSP 2 Score: 43.5134 bits (101), Expect = 2.234e-11 Identity = 31/89 (34.83%), Postives = 47/89 (52.81%), Query Frame = 3
Query: 375 LHRAIIMNDEQLLLKLLQSGKINMNIPDRYDYTPLMACAIRNLEGLFACLVEYKVELDVQNKAGKTALMLAANKGNSRMVQLLLNHGAN 641
LHRA+ E + LL+ ++N D+ TPL A LV ++V ++AG+TAL AA G++ MV+LLL+ G+N
Sbjct: 121 LHRAVASCCEDAVAVLLKH-SADVNARDKNWQTPLHVAASNKAVRCAEALVPQLSNVNVSDRAGRTALHHAAFSGHTEMVRLLLSRGSN 208 HSP 3 Score: 39.2762 bits (90), Expect = 1.067e-7 Identity = 32/99 (32.32%), Postives = 49/99 (49.49%), Query Frame = 2
Query: 650 KGMSAL-FYGVDNENIIIVRMLLEAGCDVNDTDKENEWTPLIRLAVLANNGNSKLGILLLQHGANINKQDTFGNSALIHCAFHNSHQELTRVLLSHGAN 943
+G SAL F + + +LL G +N K+ + TPL + A +G L+Q+GA ++ +D N+AL H A H+ + LL HGAN
Sbjct: 314 RGFSALHFASSSRQGALCQELLLAHGACINSRSKDGK-TPL---HMAATHGRFSCSQALIQNGAEVDCEDKNRNTAL-HIAARYGHELIITALLKHGAN 407 HSP 4 Score: 35.8094 bits (81), Expect = 1.067e-7 Identity = 26/89 (29.21%), Postives = 42/89 (47.19%), Query Frame = 3
Query: 375 LHRAIIMNDEQLLLKLLQSGKINMNIPDRYDYTPLMACAIRNLEGLFACLVEYKVELDVQNKAGKTALMLAANKGNSRMVQLLLNHGAN 641
+H A M +++ L++SG ++ D+ Y+PL A A + L+ V ++ N G T L LA G +V L+ GAN
Sbjct: 220 IHWAAYMGHLEVVKLLVESGA-EVDCKDKKGYSPLHAAASSGMSSTVHYLLGLGVHVNEANSYGNTPLHLACYNGQDVVVGELIQAGAN 307 HSP 5 Score: 41.2022 bits (95), Expect = 6.936e-7 Identity = 32/123 (26.02%), Postives = 61/123 (49.59%), Query Frame = 3
Query: 291 RLRNKNGWGEYSDEKSVHFPKEPVTGDDLHRAIIMNDEQLLLKLLQSG-KINMNIPDRYDYTPLMACAIRNLEGLFACLVEYKVELDVQNKAGKTALMLAANKGNSRMVQLLLNHGANPLLKE 656
R+R+K G+ +VH+ G L +I ++ + + SG +I + + +PL A G L+ +++DV++ G T L L+ ++G+ V LLL+HGA+P++ +
Sbjct: 542 RVRDKQGY------TAVHYAA--AYGRTLCLELIASETPFDVLMETSGTEILRDSVSQLPLSPLHLAAFHGHCGALEVLLSSLLDVDVRSPEGWTPLSLSCSRGHHECVSLLLHHGASPMIHD 656 HSP 6 Score: 30.8018 bits (68), Expect = 6.936e-7 Identity = 26/71 (36.62%), Postives = 38/71 (53.52%), Query Frame = 2
Query: 776 LAVLANNGNSKLGILLL----QHGANINKQDTFGNSALIHCAFHNSHQELTRVLLSHGANMHLKNKSGHNA 976
L A NG+++ LLL QH NI+ QD+ G + L+ A + H E LLSHGA++ ++ G A
Sbjct: 664 LHTAAMNGHAECLRLLLSNDNQH-MNIDTQDSSGQTPLM-LAVLSGHIECVYSLLSHGASVEFQDCWGRTA 732 HSP 7 Score: 48.9062 bits (115), Expect = 7.693e-6 Identity = 37/110 (33.64%), Postives = 57/110 (51.82%), Query Frame = 2
Query: 701 VRMLLEAGCDVNDTDKENEWTPLIRLAVLANNGNSKLGILLLQHGANINKQDTFGNSALIHCAFHNSHQELTRVLLSHGANMHLKNKSGHNAYQISQSMNNTNITLVMEE 1030
V +LL+ DVN DK N TPL V A+N + L+ +N+N D G +AL H AF + H E+ R+LLS G+N++ +K A + M + + ++ E
Sbjct: 133 VAVLLKHSADVNARDK-NWQTPL---HVAASNKAVRCAEALVPQLSNVNVSDRAGRTALHHAAF-SGHTEMVRLLLSRGSNINAFDKKDRRAIHWAAYMGHLEVVKLLVE 237
BLAST of Fibronectin type III and ankyrin repeat domains 1 vs. Ensembl Medaka
Match: ankrd6b (ankyrin repeat domain 6 [Source:NCBI gene;Acc:101160867]) HSP 1 Score: 65.0846 bits (157), Expect = 4.373e-11 Identity = 41/112 (36.61%), Postives = 67/112 (59.82%), Query Frame = 2
Query: 653 GMSALFYGVDNENIIIVRMLLEAGCDVNDTDKENEWTPLIRLAVLANNGNSKLGILLLQHGANINKQDTFGNSALIHCAFHNSHQELTRVLLSHGANMHLKNKSGHNAYQIS 988
G S L ++ +V +LL+AGCD+ D + + E T L R AV+ GN+ + L+Q G +++QD GN+AL A+H Q + ++L+ GAN+H KNK+G+ A ++
Sbjct: 44 GRSPLHLAAHKGHLEVVHILLKAGCDL-DIEDDGEQTALHRAAVV---GNTDVIGALIQEGCALDRQDKDGNTALHEVAWHGFSQSV-KLLVKAGANVHAKNKAGNTALHLA 150 HSP 2 Score: 21.557 bits (44), Expect = 4.373e-11 Identity = 11/25 (44.00%), Postives = 16/25 (64.00%), Query Frame = 3
Query: 576 LMLAANKGNSRMVQLLLNHGANPLL 650
L++AA+KG + V L+N GA L
Sbjct: 16 LLIAAHKGQADNVVQLINKGAKVAL 40
BLAST of Fibronectin type III and ankyrin repeat domains 1 vs. Planmine SMEST
Match: SMESG000029032.1 (SMESG000029032.1) HSP 1 Score: 432.18 bits (1110), Expect = 8.317e-152 Identity = 209/226 (92.48%), Postives = 215/226 (95.13%), Query Frame = 3
Query: 36 MSNTKIPPKIPAPAVEIVNHHMLSISWSDINKRLSLILSEEEAKCLAEISFKKINNFDEPWIVKGYADSCELEDFDQDSVYNYRIRLRNKNGWGEYSDEKSVHFPKEPVTGDDLHRAIIMNDEQLLLKLLQSGKINMNIPDRYDYTPLMACAIRNLEGLFACLVEYKVELDVQNKAGKTALMLAANKGNSRMVQLLLNHGANPLLKE----CQLYFTVSTMKILLL 701
MSNTKIPPKIPAPAVEIVNHHMLSISWSDINKRLSLILSEEEAKCLAEISFKKINNFDEPWIVKGYADSCELEDFDQDSVYNYRIRLRNKNGWGEYSDEKSVHFPKEPVTGDDLHRAIIMNDEQLLLKLLQSGKINMNIPDRYDYTPLMACAIRNLEGLFACLVEYKVELDVQNKAGKTALMLAANKGNSRMVQLLLNHGANPLLK+ L++ V I+++
Sbjct: 1 MSNTKIPPKIPAPAVEIVNHHMLSISWSDINKRLSLILSEEEAKCLAEISFKKINNFDEPWIVKGYADSCELEDFDQDSVYNYRIRLRNKNGWGEYSDEKSVHFPKEPVTGDDLHRAIIMNDEQLLLKLLQSGKINMNIPDRYDYTPLMACAIRNLEGLFACLVEYKVELDVQNKAGKTALMLAANKGNSRMVQLLLNHGANPLLKDILGMSALFYGVDNENIIIV 226 HSP 2 Score: 282.337 bits (721), Expect = 7.231e-93 Identity = 137/137 (100.00%), Postives = 137/137 (100.00%), Query Frame = 2
Query: 653 GMSALFYGVDNENIIIVRMLLEAGCDVNDTDKENEWTPLIRLAVLANNGNSKLGILLLQHGANINKQDTFGNSALIHCAFHNSHQELTRVLLSHGANMHLKNKSGHNAYQISQSMNNTNITLVMEEFLNPSHCSNEN 1063
GMSALFYGVDNENIIIVRMLLEAGCDVNDTDKENEWTPLIRLAVLANNGNSKLGILLLQHGANINKQDTFGNSALIHCAFHNSHQELTRVLLSHGANMHLKNKSGHNAYQISQSMNNTNITLVMEEFLNPSHCSNEN
Sbjct: 210 GMSALFYGVDNENIIIVRMLLEAGCDVNDTDKENEWTPLIRLAVLANNGNSKLGILLLQHGANINKQDTFGNSALIHCAFHNSHQELTRVLLSHGANMHLKNKSGHNAYQISQSMNNTNITLVMEEFLNPSHCSNEN 346
BLAST of Fibronectin type III and ankyrin repeat domains 1 vs. Planmine SMEST
Match: SMESG000029032.1 (SMESG000029032.1) HSP 1 Score: 426.787 bits (1096), Expect = 1.081e-149 Identity = 209/228 (91.67%), Postives = 215/228 (94.30%), Query Frame = 3
Query: 36 MSNTKIPPKIPAPAVEIVNHHMLSISWSDINKRLSLILSEEEAKCLAEISFKKINNFDEPWIVK--GYADSCELEDFDQDSVYNYRIRLRNKNGWGEYSDEKSVHFPKEPVTGDDLHRAIIMNDEQLLLKLLQSGKINMNIPDRYDYTPLMACAIRNLEGLFACLVEYKVELDVQNKAGKTALMLAANKGNSRMVQLLLNHGANPLLKE----CQLYFTVSTMKILLL 701
MSNTKIPPKIPAPAVEIVNHHMLSISWSDINKRLSLILSEEEAKCLAEISFKKINNFDEPWIVK GYADSCELEDFDQDSVYNYRIRLRNKNGWGEYSDEKSVHFPKEPVTGDDLHRAIIMNDEQLLLKLLQSGKINMNIPDRYDYTPLMACAIRNLEGLFACLVEYKVELDVQNKAGKTALMLAANKGNSRMVQLLLNHGANPLLK+ L++ V I+++
Sbjct: 1 MSNTKIPPKIPAPAVEIVNHHMLSISWSDINKRLSLILSEEEAKCLAEISFKKINNFDEPWIVKYMGYADSCELEDFDQDSVYNYRIRLRNKNGWGEYSDEKSVHFPKEPVTGDDLHRAIIMNDEQLLLKLLQSGKINMNIPDRYDYTPLMACAIRNLEGLFACLVEYKVELDVQNKAGKTALMLAANKGNSRMVQLLLNHGANPLLKDILGMSALFYGVDNENIIIV 228 HSP 2 Score: 282.337 bits (721), Expect = 6.762e-93 Identity = 137/137 (100.00%), Postives = 137/137 (100.00%), Query Frame = 2
Query: 653 GMSALFYGVDNENIIIVRMLLEAGCDVNDTDKENEWTPLIRLAVLANNGNSKLGILLLQHGANINKQDTFGNSALIHCAFHNSHQELTRVLLSHGANMHLKNKSGHNAYQISQSMNNTNITLVMEEFLNPSHCSNEN 1063
GMSALFYGVDNENIIIVRMLLEAGCDVNDTDKENEWTPLIRLAVLANNGNSKLGILLLQHGANINKQDTFGNSALIHCAFHNSHQELTRVLLSHGANMHLKNKSGHNAYQISQSMNNTNITLVMEEFLNPSHCSNEN
Sbjct: 212 GMSALFYGVDNENIIIVRMLLEAGCDVNDTDKENEWTPLIRLAVLANNGNSKLGILLLQHGANINKQDTFGNSALIHCAFHNSHQELTRVLLSHGANMHLKNKSGHNAYQISQSMNNTNITLVMEEFLNPSHCSNEN 348
BLAST of Fibronectin type III and ankyrin repeat domains 1 vs. Planmine SMEST
Match: SMESG000033969.1 (SMESG000033969.1) HSP 1 Score: 158.303 bits (399), Expect = 1.851e-59 Identity = 79/201 (39.30%), Postives = 128/201 (63.68%), Query Frame = 3
Query: 48 KIPPKIPAPAVEIVNHHMLSISWSDINKRLSLILS-EEEAKCLAEISFKKINNFDEPW--IVKGYADSCELEDFDQDSVYNYRIRLRNKNGWGEYSDEKSVHFPKEPVTGDDLHRAIIMNDEQLLLKLLQSGKINMNIPDRYDYTPLMACAIRNLEGLFACLVEYKVELDVQNKAGKTALMLAANKGNSRMVQLLLNHGAN 641
K+PPK P P V + H ++ +W + RL + + + + + L+E+ +K++ DE W I GY SC + + + Y+Y++R +NKNGWG++SDE + K+P+TG+ +HRAI + +++ LL++L+ G+ N+ D D+TPLMA A + L L+E+K +L+ QNK+GKTALMLAA KG+ V +L+ GAN
Sbjct: 4 KVPPKAPQPIVGEITHFTVNFNWKEYLDRLKEVFNPKTDGRILSEMQ-QKLDTKDE-WSTIYSGYDSSCTARNLESECSYSYKLRFKNKNGWGQFSDEVHIRSLKQPLTGEHIHRAIRIENKEDLLQILEKGEANIEAQDNLDFTPLMAAAQKGLSEFVKILIEWKADLEAQNKSGKTALMLAAFKGHVECVDILVEGGAN 202 HSP 2 Score: 90.5077 bits (223), Expect = 1.851e-59 Identity = 52/135 (38.52%), Postives = 75/135 (55.56%), Query Frame = 2
Query: 653 GMSALFYGVDNENIIIVRMLLEAGCDVNDTDKENEWTPLIRLAVLANNGNSKLGILLLQHGANINKQDTFGNSALIHCAFHNSHQELTRVLLSHGANMHLKNKSGHNAYQISQSMNNTNITLVMEEFLNPSHCSN 1057
G+ L Y VD E ++R L+ G +VN DK EWTPLIR A L NNGN + L++ A ++ D G +AL H A N+H +LT LL GA++ + GHNAY ++ S++ + +EEF+ N
Sbjct: 210 GLGVLHYAVDGEQPNMIRKLISLGANVNAVDKAMEWTPLIRCAGLKNNGNVLIAHELIRGNAVVDLTDNEGKTAL-HNAILNNHAKLTTFLLEKGASLEVCTNQGHNAYTLADSLDVRASKVAIEEFIEKQKSIN 343
BLAST of Fibronectin type III and ankyrin repeat domains 1 vs. Planmine SMEST
Match: SMESG000030957.1 (SMESG000030957.1) HSP 1 Score: 101.293 bits (251), Expect = 5.242e-42 Identity = 59/200 (29.50%), Postives = 113/200 (56.50%), Query Frame = 3
Query: 48 KIPPKIPAPAVEIVNHHMLSISWSDINKRLSLILSEEEAKCLAEISFKKINNFDEPW--IVKGYADSCELEDFDQDSVYNYRIRLRNKNGWGEYSDEKSVHFPKEPVTGDDLHRAIIMNDEQLLLKLLQSGKINMNIPDRYDYTPLMACAIRNLEGLFACLVEYKVELDVQNKAGKTALMLAANKGNSRMVQLLLNHGAN 641
KI K P V +H+ + W + ++ + + +E K L E+S + +E W I GYA + + ++ Y ++IR++ ++ W +YSD + +P+TG+++H+AI N+ + LL++L++GK+N+ D +TPLM + ++L + L++ +++ + +GK+ALMLA KG + LL+ +GAN
Sbjct: 3 KIIWKPSPPTVTEFSHYSALLDWQEQCDKI--LKTHQEKKILTEVSMIE-QKSEEGWKRIYIGYATNFTGNNLHHNTKYAFKIRMKVRDEWSQYSDPVIIVSLDKPMTGENIHKAIRSNNIKELLEVLENGKVNIEAQDGLGFTPLMVASQKSLTEIMKLLLKKLADIEAKTDSGKSALMLACFKGEWEAIDLLIQYGAN 199 HSP 2 Score: 88.9669 bits (219), Expect = 5.242e-42 Identity = 50/128 (39.06%), Postives = 80/128 (62.50%), Query Frame = 2
Query: 656 MSALFYGVDNENIIIVRMLLEAGCDVNDTDKENEWTPLIRLAVLANNGNSKLGILLLQHGANINKQDTFGNSALIHCAFHNSHQELTRVLLSHGANMHLKNKSGHNAYQISQSMNNTNITLVMEEFLN 1039
++AL Y VD E+ +R+L AG D++ TD W+PL+R A L NNGN + LL+ GAN+N QD GN+AL H A N H +L VLL+ G ++NK ++A ++ ++ +N + ++++FL+
Sbjct: 208 LTALHYAVDGESTRAIRILGAAGADIDPTDSILGWSPLLRCAGLKNNGNVDVARELLKLGANVNLQDKEGNTAL-HLAAINGHYKLFEVLLNAGTESSIQNKLKNSATKLVENSDNLAMKQILQQFLS 334
BLAST of Fibronectin type III and ankyrin repeat domains 1 vs. Planmine SMEST
Match: SMESG000026655.1 (SMESG000026655.1) HSP 1 Score: 47.3654 bits (111), Expect = 3.588e-12 Identity = 36/112 (32.14%), Postives = 57/112 (50.89%), Query Frame = 2
Query: 653 GMSALFYGVDNENIIIVRMLLEAGCDVNDTDKENEWTPLIRLAVLANNGNSKLGILLLQHGANINKQDTFGNSALIHCAFHNSHQELTRVLLSHGANMHLKNKSGHNAYQIS 988
G + L N+ + ++L+E DVN K N TPL V A G ++ LL+ AN+N G S IHCA + + + +LL +GA++ K+K+G A Q++
Sbjct: 267 GFTPLHIAAHYNNVNVAKLLIEKNADVNFPAKNN-ITPL---HVAAKWGKEEMLKLLISQKANVNSVTRDGLSP-IHCAARSGFENIILILLENGADIQHKSKNGLTALQMA 373 HSP 2 Score: 42.3578 bits (98), Expect = 3.588e-12 Identity = 23/74 (31.08%), Postives = 39/74 (52.70%), Query Frame = 3
Query: 411 LLKLLQSGKINMNIPDRYDYTPLMACAIRNLEGLFACLVEYKVELDVQNKAGKTALMLAANKGNSRMVQLLLNH 632
++ LL K N+N+ + +TPL A N + L+EY + G T L +A +GN ++VQ+LL++
Sbjct: 153 VVSLLLESKANINVKSQNGFTPLYMAAQENHLDVVKVLLEYGANQAITTDDGFTPLAVALQQGNDKVVQILLDN 226 The following BLAST results are available for this feature:
BLAST of Fibronectin type III and ankyrin repeat domains 1 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99) Total hits: 5
BLAST of Fibronectin type III and ankyrin repeat domains 1 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99) Total hits: 5
BLAST of Fibronectin type III and ankyrin repeat domains 1 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99) Total hits: 5
BLAST of Fibronectin type III and ankyrin repeat domains 1 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99) Total hits: 5
BLAST of Fibronectin type III and ankyrin repeat domains 1 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99) Total hits: 5
BLAST of Fibronectin type III and ankyrin repeat domains 1 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99) Total hits: 5
BLAST of Fibronectin type III and ankyrin repeat domains 1 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt) Total hits: 5
BLAST of Fibronectin type III and ankyrin repeat domains 1 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL) Total hits: 5
BLAST of Fibronectin type III and ankyrin repeat domains 1 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99) Total hits: 5
BLAST of Fibronectin type III and ankyrin repeat domains 1 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99) Total hits: 5
BLAST of Fibronectin type III and ankyrin repeat domains 1 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46) Total hits: 1
BLAST of Fibronectin type III and ankyrin repeat domains 1 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46) Total hits: 4
BLAST of Fibronectin type III and ankyrin repeat domains 1 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99) Total hits: 5
BLAST of Fibronectin type III and ankyrin repeat domains 1 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST) Total hits: 5
Analyses
This transcript is derived from or has results from the following analyses Sequences
The following sequences are available for this feature:
transcript sequence >SMED30013415 ID=SMED30013415|Name=Fibronectin type III and ankyrin repeat domains 1|organism=Schmidtea mediterranea sexual|type=transcript|length=1128bpback to top protein sequence of SMED30013415-orf-1 >SMED30013415-orf-1 ID=SMED30013415-orf-1|Name=SMED30013415-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=137bp MSALFYGVDNENIIIVRMLLEAGCDVNDTDKENEWTPLIRLAVLANNGNSback to top protein sequence of SMED30013415-orf-2 >SMED30013415-orf-2 ID=SMED30013415-orf-2|Name=SMED30013415-orf-2|organism=Schmidtea mediterranea sexual|type=polypeptide|length=234bp LPIWKIQITLLMSNTKIPPKIPAPAVEIVNHHMLSISWSDINKRLSLILSback to top Annotated Terms
The following terms have been associated with this transcript:
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
|
