Elongation factor 2 kinase

Overview
NameElongation factor 2 kinase
Smed IDSMED30013397
Length (bp)2717
Neoblast Clusters

Zeng et. al., 2018



▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)



Explore this single cell expression dataset with our NB Cluster Shiny App



 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of Elongation factor 2 kinase (SMED30013397) t-SNE clustered cells

Violin plots show distribution of expression levels for Elongation factor 2 kinase (SMED30013397) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of Elongation factor 2 kinase (SMED30013397) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for Elongation factor 2 kinase (SMED30013397) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020



SMED30013397

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 8

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
intestinal phagocyteSMED30013397SMESG000081415.1 SMESG000065760.1 SMESG000064506.1 SMESG000061313.1 SMESG000056432.1 SMESG000051530.1 SMESG000034660.1 SMESG000026901.1 SMESG000022344.1 Contig6192newmark_estsPMID:23079596
Forsthoefel et al., 2012		FACS sorted cell population asexual adult cDNA to DNA expression microarray evidence
intestinal phagocyteSMED30013397SMESG000081415.1 SMESG000065760.1 SMESG000064506.1 SMESG000061313.1 SMESG000056432.1 SMESG000051530.1 SMESG000034660.1 SMESG000026901.1 SMESG000022344.1 Contig6192uc_Smed_v2PMID:23079596
Forsthoefel et al., 2012		FACS sorted cell population asexual adult cDNA to DNA expression microarray evidence
parapharyngeal regionSMED30013397SMESG000034660.1 dd_Smed_v4_2651_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
Smed sexual biotypeSMED30013397SMESG000081415.1 SMESG000065760.1 SMESG000064506.1 SMESG000061313.1 SMESG000056432.1 SMESG000051530.1 SMESG000034660.1 SMESG000026901.1 SMESG000022344.1 Contig6192newmark_estsPMID:29674431
Fincher et al., 2018		FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
Smed sexual biotypeSMED30013397SMESG000081415.1 SMESG000065760.1 SMESG000064506.1 SMESG000061313.1 SMESG000056432.1 SMESG000051530.1 SMESG000034660.1 SMESG000026901.1 SMESG000022344.1 Contig6192uc_Smed_v2PMID:29674431
Fincher et al., 2018		FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
Smed sexual biotypeSMED30013397SMESG000081415.1 SMESG000078681.1 SMESG000077975.1 SMESG000065760.1 SMESG000064506.1 SMESG000061313.1 SMESG000056432.1 SMESG000051530.1 SMESG000036073.1 SMESG000026901.1 SMESG000022344.1 SMESG000034660.1 Contig39361newmark_estsPMID:29674431
Fincher et al., 2018		FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
Smed sexual biotypeSMED30013397SMESG000081415.1 SMESG000078681.1 SMESG000077975.1 SMESG000065760.1 SMESG000064506.1 SMESG000061313.1 SMESG000056432.1 SMESG000051530.1 SMESG000036073.1 SMESG000026901.1 SMESG000022344.1 SMESG000034660.1 Contig39361uc_Smed_v2PMID:29674431
Fincher et al., 2018		FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
epidermisSMED30013397SMESG000034660.1 dd_Smed_v4_2651_0_1dd_Smed_v4PMID:28292427
Wurtzel et al., 2017		whole organism asexual adult single-cell RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
[Close]
BLAST of Elongation factor 2 kinase vs. Ensembl Human
Match: EEF2K (eukaryotic elongation factor 2 kinase [Source:HGNC Symbol;Acc:HGNC:24615])

HSP 1 Score: 304.679 bits (779), Expect = 2.800e-94
Identity = 151/253 (59.68%), Postives = 192/253 (75.89%), Query Frame = 3 
Query:  408 WFRAVSKICKHDDDIDPWHDFTIDTIKPDKAIRYRYSAIKKKWVQDEIWVKLETLPFDHGAMRECFRLKKLSTTGINNNHDWNFSSNYVAKQYINLVNRDVYFEDVKLQMESKLWAEEYNRQNPPKKIDIFQLSIIELIDRENKPLYHIEHFMEGTYLKYNSNSGYVDDSCLRNTPQAFSHFTFERSGHRIIIVDIQGVGDLYTDPQVHTAXXXXXXXXXXXXXXMALFFSSHRCNPICHYLGLSEFDMHQNE 1166
            W  A+ K  KH  D  PW +F ++ I  ++A R+RY+A+  +W+ DE+ +K+ + PF  GAMRECFR KKLS     +   W  +SNYVAK+YI  V+RDVYFEDV+LQME+KLW EEYNR  PPK++DI Q+ IIEL DR  KPL+H+EH++EG Y+KYNSNSG+V D  +R TPQAFSHFTFERSGH++I+VDIQGVGDLYTDPQ+HT  G ++GDGNLG+RGMALFF SH CN IC  +GL+ FD+   E
Sbjct:   85 WKHAIQK-AKHMPD--PWAEFHLEDIATERATRHRYNAVTGEWLDDEVLIKMASQPFGRGAMRECFRTKKLSN--FLHAQQWKGASNYVAKRYIEPVDRDVYFEDVRLQMEAKLWGEEYNRHKPPKQVDIMQMCIIELKDRPGKPLFHLEHYIEGKYIKYNSNSGFVRDDNIRLTPQAFSHFTFERSGHQLIVVDIQGVGDLYTDPQIHTETGTDFGDGNLGVRGMALFFYSHACNRICESMGLAPFDLSPRE 332
[Close]
BLAST of Elongation factor 2 kinase vs. Ensembl Human
Match: EEF2K (eukaryotic elongation factor 2 kinase [Source:HGNC Symbol;Acc:HGNC:24615])

HSP 1 Score: 303.908 bits (777), Expect = 2.242e-90
Identity = 151/253 (59.68%), Postives = 192/253 (75.89%), Query Frame = 3 
Query:  408 WFRAVSKICKHDDDIDPWHDFTIDTIKPDKAIRYRYSAIKKKWVQDEIWVKLETLPFDHGAMRECFRLKKLSTTGINNNHDWNFSSNYVAKQYINLVNRDVYFEDVKLQMESKLWAEEYNRQNPPKKIDIFQLSIIELIDRENKPLYHIEHFMEGTYLKYNSNSGYVDDSCLRNTPQAFSHFTFERSGHRIIIVDIQGVGDLYTDPQVHTAXXXXXXXXXXXXXXMALFFSSHRCNPICHYLGLSEFDMHQNE 1166
            W  A+ K  KH  D  PW +F ++ I  ++A R+RY+A+  +W+ DE+ +K+ + PF  GAMRECFR KKLS     +   W  +SNYVAK+YI  V+RDVYFEDV+LQME+KLW EEYNR  PPK++DI Q+ IIEL DR  KPL+H+EH++EG Y+KYNSNSG+V D  +R TPQAFSHFTFERSGH++I+VDIQGVGDLYTDPQ+HT  G ++GDGNLG+RGMALFF SH CN IC  +GL+ FD+   E
Sbjct:   85 WKHAIQK-AKHMPD--PWAEFHLEDIATERATRHRYNAVTGEWLDDEVLIKMASQPFGRGAMRECFRTKKLSN--FLHAQQWKGASNYVAKRYIEPVDRDVYFEDVRLQMEAKLWGEEYNRHKPPKQVDIMQMCIIELKDRPGKPLFHLEHYIEGKYIKYNSNSGFVRDDNIRLTPQAFSHFTFERSGHQLIVVDIQGVGDLYTDPQIHTETGTDFGDGNLGVRGMALFFYSHACNRICESMGLAPFDLSPRE 332

HSP 2 Score: 123.635 bits (309), Expect = 2.890e-28
Identity = 88/263 (33.46%), Postives = 129/263 (49.05%), Query Frame = 3 
Query: 1752 NLDQEIGHSILAQVHHELARLHESGRFVKSKRLAPGCLHHQFWSNLLNENDSPEESEQKSPTNHDLDINWESCLFHERHAAQLGCLEAVIVMARYCLNMSGHMLQDCPLPPNQNDIECGLDYLWRAADSGDRRSMIELANLYRKTEYFGEIFNEINKTTLEVNWFEAVKWYKRAFEAVNKLDGQIDSKDAEGRYDSAEDLMPPQEILASMAELYLKGGYGLEKNCQLAGELYSQAAEIATNALQGRQAVKYYELADTAYSQDE 2540
            +L+++IG SIL +VH  + R HE GRF         C   + W                           ES +FH  HAA LG LEA++ +      +  H+L D  L   + +   G DYL +AA++GDR+SMI +A  +   +       +        +W EA+ WY  A E  +  +G        G YD  +D  P   +LA  AE+   GGYGLEK+ Q +G+LY+QAAE A  A++GR A +YY+ A+ A++Q E
Sbjct:  513 DLEKKIGKSILGKVHLAMVRYHEGGRF---------CEKGEEWDQ-------------------------ESAVFHLEHAANLGELEAIVGLGLMYSQLPHHILADVSLKETEENKTKGFDYLLKAAEAGDRQSMILVARAFDSGQNLSPDRCQ--------DWLEALHWYNTALEMTDCDEG--------GEYDGMQD-EPRYMMLAREAEMLFTGGYGLEKDPQRSGDLYTQAAEAAMEAMKGRLANQYYQKAEEAWAQME 724
[Close]
BLAST of Elongation factor 2 kinase vs. Ensembl Human
Match: EEF2K (eukaryotic elongation factor 2 kinase [Source:HGNC Symbol;Acc:HGNC:24615])

HSP 1 Score: 303.908 bits (777), Expect = 2.242e-90
Identity = 151/253 (59.68%), Postives = 192/253 (75.89%), Query Frame = 3 
Query:  408 WFRAVSKICKHDDDIDPWHDFTIDTIKPDKAIRYRYSAIKKKWVQDEIWVKLETLPFDHGAMRECFRLKKLSTTGINNNHDWNFSSNYVAKQYINLVNRDVYFEDVKLQMESKLWAEEYNRQNPPKKIDIFQLSIIELIDRENKPLYHIEHFMEGTYLKYNSNSGYVDDSCLRNTPQAFSHFTFERSGHRIIIVDIQGVGDLYTDPQVHTAXXXXXXXXXXXXXXMALFFSSHRCNPICHYLGLSEFDMHQNE 1166
            W  A+ K  KH  D  PW +F ++ I  ++A R+RY+A+  +W+ DE+ +K+ + PF  GAMRECFR KKLS     +   W  +SNYVAK+YI  V+RDVYFEDV+LQME+KLW EEYNR  PPK++DI Q+ IIEL DR  KPL+H+EH++EG Y+KYNSNSG+V D  +R TPQAFSHFTFERSGH++I+VDIQGVGDLYTDPQ+HT  G ++GDGNLG+RGMALFF SH CN IC  +GL+ FD+   E
Sbjct:   85 WKHAIQK-AKHMPD--PWAEFHLEDIATERATRHRYNAVTGEWLDDEVLIKMASQPFGRGAMRECFRTKKLSN--FLHAQQWKGASNYVAKRYIEPVDRDVYFEDVRLQMEAKLWGEEYNRHKPPKQVDIMQMCIIELKDRPGKPLFHLEHYIEGKYIKYNSNSGFVRDDNIRLTPQAFSHFTFERSGHQLIVVDIQGVGDLYTDPQIHTETGTDFGDGNLGVRGMALFFYSHACNRICESMGLAPFDLSPRE 332

HSP 2 Score: 123.635 bits (309), Expect = 2.890e-28
Identity = 88/263 (33.46%), Postives = 129/263 (49.05%), Query Frame = 3 
Query: 1752 NLDQEIGHSILAQVHHELARLHESGRFVKSKRLAPGCLHHQFWSNLLNENDSPEESEQKSPTNHDLDINWESCLFHERHAAQLGCLEAVIVMARYCLNMSGHMLQDCPLPPNQNDIECGLDYLWRAADSGDRRSMIELANLYRKTEYFGEIFNEINKTTLEVNWFEAVKWYKRAFEAVNKLDGQIDSKDAEGRYDSAEDLMPPQEILASMAELYLKGGYGLEKNCQLAGELYSQAAEIATNALQGRQAVKYYELADTAYSQDE 2540
            +L+++IG SIL +VH  + R HE GRF         C   + W                           ES +FH  HAA LG LEA++ +      +  H+L D  L   + +   G DYL +AA++GDR+SMI +A  +   +       +        +W EA+ WY  A E  +  +G        G YD  +D  P   +LA  AE+   GGYGLEK+ Q +G+LY+QAAE A  A++GR A +YY+ A+ A++Q E
Sbjct:  513 DLEKKIGKSILGKVHLAMVRYHEGGRF---------CEKGEEWDQ-------------------------ESAVFHLEHAANLGELEAIVGLGLMYSQLPHHILADVSLKETEENKTKGFDYLLKAAEAGDRQSMILVARAFDSGQNLSPDRCQ--------DWLEALHWYNTALEMTDCDEG--------GEYDGMQD-EPRYMMLAREAEMLFTGGYGLEKDPQRSGDLYTQAAEAAMEAMKGRLANQYYQKAEEAWAQME 724
[Close]
BLAST of Elongation factor 2 kinase vs. Ensembl Human
Match: EEF2K (eukaryotic elongation factor 2 kinase [Source:HGNC Symbol;Acc:HGNC:24615])

HSP 1 Score: 303.908 bits (777), Expect = 2.360e-90
Identity = 151/253 (59.68%), Postives = 192/253 (75.89%), Query Frame = 3 
Query:  408 WFRAVSKICKHDDDIDPWHDFTIDTIKPDKAIRYRYSAIKKKWVQDEIWVKLETLPFDHGAMRECFRLKKLSTTGINNNHDWNFSSNYVAKQYINLVNRDVYFEDVKLQMESKLWAEEYNRQNPPKKIDIFQLSIIELIDRENKPLYHIEHFMEGTYLKYNSNSGYVDDSCLRNTPQAFSHFTFERSGHRIIIVDIQGVGDLYTDPQVHTAXXXXXXXXXXXXXXMALFFSSHRCNPICHYLGLSEFDMHQNE 1166
            W  A+ K  KH  D  PW +F ++ I  ++A R+RY+A+  +W+ DE+ +K+ + PF  GAMRECFR KKLS     +   W  +SNYVAK+YI  V+RDVYFEDV+LQME+KLW EEYNR  PPK++DI Q+ IIEL DR  KPL+H+EH++EG Y+KYNSNSG+V D  +R TPQAFSHFTFERSGH++I+VDIQGVGDLYTDPQ+HT  G ++GDGNLG+RGMALFF SH CN IC  +GL+ FD+   E
Sbjct:   85 WKHAIQK-AKHMPD--PWAEFHLEDIATERATRHRYNAVTGEWLDDEVLIKMASQPFGRGAMRECFRTKKLSN--FLHAQQWKGASNYVAKRYIEPVDRDVYFEDVRLQMEAKLWGEEYNRHKPPKQVDIMQMCIIELKDRPGKPLFHLEHYIEGKYIKYNSNSGFVRDDNIRLTPQAFSHFTFERSGHQLIVVDIQGVGDLYTDPQIHTETGTDFGDGNLGVRGMALFFYSHACNRICESMGLAPFDLSPRE 332

HSP 2 Score: 123.635 bits (309), Expect = 2.993e-28
Identity = 88/263 (33.46%), Postives = 129/263 (49.05%), Query Frame = 3 
Query: 1752 NLDQEIGHSILAQVHHELARLHESGRFVKSKRLAPGCLHHQFWSNLLNENDSPEESEQKSPTNHDLDINWESCLFHERHAAQLGCLEAVIVMARYCLNMSGHMLQDCPLPPNQNDIECGLDYLWRAADSGDRRSMIELANLYRKTEYFGEIFNEINKTTLEVNWFEAVKWYKRAFEAVNKLDGQIDSKDAEGRYDSAEDLMPPQEILASMAELYLKGGYGLEKNCQLAGELYSQAAEIATNALQGRQAVKYYELADTAYSQDE 2540
            +L+++IG SIL +VH  + R HE GRF         C   + W                           ES +FH  HAA LG LEA++ +      +  H+L D  L   + +   G DYL +AA++GDR+SMI +A  +   +       +        +W EA+ WY  A E  +  +G        G YD  +D  P   +LA  AE+   GGYGLEK+ Q +G+LY+QAAE A  A++GR A +YY+ A+ A++Q E
Sbjct:  513 DLEKKIGKSILGKVHLAMVRYHEGGRF---------CEKGEEWDQ-------------------------ESAVFHLEHAANLGELEAIVGLGLMYSQLPHHILADVSLKETEENKTKGFDYLLKAAEAGDRQSMILVARAFDSGQNLSPDRCQ--------DWLEALHWYNTALEMTDCDEG--------GEYDGMQD-EPRYMMLAREAEMLFTGGYGLEKDPQRSGDLYTQAAEAAMEAMKGRLANQYYQKAEEAWAQME 724
[Close]
BLAST of Elongation factor 2 kinase vs. Ensembl Human
Match: ALPK1 (alpha kinase 1 [Source:HGNC Symbol;Acc:HGNC:20917])

HSP 1 Score: 72.7886 bits (177), Expect = 2.500e-12
Identity = 61/239 (25.52%), Postives = 111/239 (46.44%), Query Frame = 3 
Query:  486 KPDKAIRYRYSAIKKKWVQDEIWVKLETLPFDHGAMRECFRLKKLSTTGINNNHDWNFSSNYVAKQYINLVNRDVYFEDVKLQMESKLWAEEYNR----QNPPKKIDIFQLSIIELI-DRENKPLYHIEHFMEGTYLKYNSNSGYVD-DSCLRNTPQAFSHFTFERSGHRIIIVDIQ------GVGDLY-TDPQVHTAXXXXXXXXXXXXXXMALFFSSH-RCNPICHYLGLSEFDMHQ 1160
            KP +  R   + + K   + E+W   ET+ +    +    + ++ +   +++ H       YV K Y        +F DV+ QM ++ +  E+N+    QN P +I     +I+ ++ D+  K    +E ++ G ++K ++N+  V  +        A+ HF++E S HR ++VD+Q      G G +Y TDPQ+H+ D   +            F + H  CN ICH L L+   M +
Sbjct:  925 KPSQLHRAHSALLLKYSKKSELWTAQETIVYLGDYLTVKKKGRQRNAFWVHHLHQEEILGRYVGKDYKEQKGLWHHFTDVERQMTAQHYVTEFNKRLYEQNIPTQIFYIPSTILLILEDKTIKGCISVEPYILGEFVKLSNNTKVVKTEYKATEYGLAYGHFSYEFSNHRDVVVDLQGWVTGNGKGLIYLTDPQIHSVDQKVFTTNFGKRGIFYFFNNQHVECNEICHRLSLTRPSMEK 1163
[Close]
BLAST of Elongation factor 2 kinase vs. Ensembl Celegans
Match: efk-1 (Eukaryotic elongation factor 2 kinase [Source:UniProtKB/Swiss-Prot;Acc:O01991])

HSP 1 Score: 294.664 bits (753), Expect = 4.208e-87
Identity = 152/250 (60.80%), Postives = 190/250 (76.00%), Query Frame = 3 
Query:  450 IDPWHDFTIDTIKPDKAIRYRYSAIKKKWVQDEIWVKLETLPFDHGAMRECFRLKKLSTTGINNNHDWNFSSNYVAKQYINLVNRDVYFEDVKLQMESKLWAEEYNRQNPPKKIDIFQLSIIELIDRENKPLYHIEHFMEGTYLKYNSNSGYVDDSCLRNTPQAFSHFTFERSGHRIIIVDIQGVGDLYTDPQVHTAXXXXXXXXXXXXXXMALFFSSHRCNPICHYLGLSEFDMHQNELVDNDLDQEIA 1199
            IDPW +F I      +A RYRYSAI+K+W +D + V+L    F  GAMREC+RLKK S  G   + DW  SSNYVAK+YI  V+R V F+DV+LQM++KLWAEEYNR NPPKKIDI Q+ +IE+ID +  PLYH+EHF+EG Y+KYNSNSG+V ++  R TPQAFSHFTFERSGH++++VDIQGVGDLYTDPQ+HT  G +YGDGNLG RGMALFF SHRCN IC  + LS F++   E+   ++  E+A
Sbjct:   82 IDPWDEFNIHEYPVQRAKRYRYSAIRKQWTEDIVDVRLHPDSFARGAMRECYRLKKCSKHG--TSQDW--SSNYVAKRYICQVDRRVLFDDVRLQMDAKLWAEEYNRYNPPKKIDIVQMCVIEMIDVKGSPLYHLEHFIEGKYIKYNSNSGFVSNAA-RLTPQAFSHFTFERSGHQMMVVDIQGVGDLYTDPQIHTVVGTDYGDGNLGTRGMALFFHSHRCNDICETMDLSNFELSPPEIEATEVAMEVA 326

HSP 2 Score: 90.1225 bits (222), Expect = 2.979e-18
Identity = 88/289 (30.45%), Postives = 147/289 (50.87%), Query Frame = 3 
Query: 1707 SMKENQKPSSATHPTNLDQEIGH--SILAQVHHELARLHESGRFVKS----KRLAPGCLHHQFWSNLLNENDSPEESEQKSPTNHDLDINWESCLFHERHAAQLGCLEAVIVMARYCLNMSGHMLQDCP---LPPN-----QNDI----ECGLDYLWRAADSGDRRSMIELANLYRKTEYFGEIFNEINKTTLEVNWFEAVKWYKRAFEAVNKLDGQIDSKDAEGRYDSAEDLMPPQEILASMAELYLKGGYGLEKNCQLAGELYSQAAEIATNALQGRQAVKYYELAD 2519
            S++  Q  ++  +  ++ Q  GH  S+L Q+H +L+R HE GRFV+     K +  G           +END+      + P  +D     +S +FH   A + G LEAV+  A   L +   +L++     L PN     +N I    E G D +  AA+ GD+ +M+ +A+ Y   ++ G      N+ T   ++ +++ WY+R      + + ++DS   +  + S   L    EILA MAE+Y +GGYGL ++ + A  L+++AAE A  A+ G+ A KYYE A+
Sbjct:  500 SLQLQQMAANLENDEDVPQVTGHQFSVLGQIHIDLSRYHELGRFVEVDSEHKEMLEG-----------SENDA------RVPIKYDK----QSAIFHLDIARKCGILEAVLTSAHIVLGLPHELLKEVTVDDLFPNGFGEQENGIRDLEEFGSDLMEIAAEMGDKGAMLYMAHAYETGQHLGP-----NRRT---DYKKSIDWYQRVVGF--QEEEELDSDCGKTTFSSFAPLTR-HEILAKMAEMYKEGGYGLNQDFERAYGLFNEAAEAAMEAMNGKLANKYYEKAE 756
[Close]
BLAST of Elongation factor 2 kinase vs. Ensembl Celegans
Match: efk-1 (Eukaryotic elongation factor 2 kinase [Source:UniProtKB/Swiss-Prot;Acc:O01991])

HSP 1 Score: 294.664 bits (753), Expect = 5.668e-87
Identity = 152/250 (60.80%), Postives = 190/250 (76.00%), Query Frame = 3 
Query:  450 IDPWHDFTIDTIKPDKAIRYRYSAIKKKWVQDEIWVKLETLPFDHGAMRECFRLKKLSTTGINNNHDWNFSSNYVAKQYINLVNRDVYFEDVKLQMESKLWAEEYNRQNPPKKIDIFQLSIIELIDRENKPLYHIEHFMEGTYLKYNSNSGYVDDSCLRNTPQAFSHFTFERSGHRIIIVDIQGVGDLYTDPQVHTAXXXXXXXXXXXXXXMALFFSSHRCNPICHYLGLSEFDMHQNELVDNDLDQEIA 1199
            IDPW +F I      +A RYRYSAI+K+W +D + V+L    F  GAMREC+RLKK S  G   + DW  SSNYVAK+YI  V+R V F+DV+LQM++KLWAEEYNR NPPKKIDI Q+ +IE+ID +  PLYH+EHF+EG Y+KYNSNSG+V ++  R TPQAFSHFTFERSGH++++VDIQGVGDLYTDPQ+HT  G +YGDGNLG RGMALFF SHRCN IC  + LS F++   E+   ++  E+A
Sbjct:   82 IDPWDEFNIHEYPVQRAKRYRYSAIRKQWTEDIVDVRLHPDSFARGAMRECYRLKKCSKHG--TSQDW--SSNYVAKRYICQVDRRVLFDDVRLQMDAKLWAEEYNRYNPPKKIDIVQMCVIEMIDVKGSPLYHLEHFIEGKYIKYNSNSGFVSNAA-RLTPQAFSHFTFERSGHQMMVVDIQGVGDLYTDPQIHTVVGTDYGDGNLGTRGMALFFHSHRCNDICETMDLSNFELSPPEIEATEVAMEVA 326

HSP 2 Score: 86.6557 bits (213), Expect = 3.641e-17
Identity = 88/297 (29.63%), Postives = 147/297 (49.49%), Query Frame = 3 
Query: 1707 SMKENQKPSSATHPTNLDQEIGH--SILAQVHHELARLHESGRFVK----SKRLAPGCLHHQFWSNLLNENDSPEESEQKSPTNHDLDINWESCLFHERHAAQLGCLEAVIVMARYCLNMSGHMLQDCP---LPPN-----QNDI------------ECGLDYLWRAADSGDRRSMIELANLYRKTEYFGEIFNEINKTTLEVNWFEAVKWYKRAFEAVNKLDGQIDSKDAEGRYDSAEDLMPPQEILASMAELYLKGGYGLEKNCQLAGELYSQAAEIATNALQGRQAVKYYELAD 2519
            S++  Q  ++  +  ++ Q  GH  S+L Q+H +L+R HE GRFV+     K +  G           +END+      + P  +D     +S +FH   A + G LEAV+  A   L +   +L++     L PN     +N I            E G D +  AA+ GD+ +M+ +A+ Y   ++ G      N+ T   ++ +++ WY+R      + + ++DS   +  + S   L    EILA MAE+Y +GGYGL ++ + A  L+++AAE A  A+ G+ A KYYE A+
Sbjct:  500 SLQLQQMAANLENDEDVPQVTGHQFSVLGQIHIDLSRYHELGRFVEVDSEHKEMLEG-----------SENDA------RVPIKYDK----QSAIFHLDIARKCGILEAVLTSAHIVLGLPHELLKEVTVDDLFPNGFGEQENGIRADKGQKPCDLEEFGSDLMEIAAEMGDKGAMLYMAHAYETGQHLGP-----NRRT---DYKKSIDWYQRVVGF--QEEEELDSDCGKTTFSSFAPLTR-HEILAKMAEMYKEGGYGLNQDFERAYGLFNEAAEAAMEAMNGKLANKYYEKAE 764
[Close]
BLAST of Elongation factor 2 kinase vs. Ensembl Zebrafish
Match: eef2k (eukaryotic elongation factor 2 kinase [Source:ZFIN;Acc:ZDB-GENE-020916-2])

HSP 1 Score: 380.178 bits (975), Expect = 6.972e-119
Identity = 247/703 (35.14%), Postives = 381/703 (54.20%), Query Frame = 3 
Query:  453 DPWHDFTIDTIKPDKAIRYRYSAIKKKWVQDEIWVKLETLPFDHGAMRECFRLKKLSTTGINNNHDWNFSSNYVAKQYINLVNRDVYFEDVKLQMESKLWAEEYNRQNPPKKIDIFQLSIIELIDRENKPLYHIEHFMEGTYLKYNSNSGYVDDSCLRNTPQAFSHFTFERSGHRIIIVDIQGVGDLYTDPQVHTAXXXXXXXXXXXXXXMALFFSSHRCNPICHYLGLSEFDMHQNELVDNDLDQEIADHDISTISIDALPEEDSCAFSSKSYNEIKKRNRSISFKMSGTVIRDGRTSPCVTSPAFLDQLFPAPIDLIRAMSVDSGVQSVSTPFVSQGNFMTXXXXXXXXXXXXXXXXXXXXHSGLGAYHHPYEIKTNLSQIINSRKLFRRRQRNYSDGSDIDASLVSYEEHLAVYYSMKEN-QKPSSATHPTN------LDQEIGHSILAQVHHELARLHESGRFVKSKRLAPGCLHHQFWSNLLNENDSPEESEQKSPTNHDLDINWESCLFHERHAAQLGCLEAVIVMARYCLNMSGHMLQDCPLPPNQNDIECGLDYLWRAADSGDRRSMIELANLYRKTEYFGEIFNEINKTTLEVNWFEAVKWYKRAFEAVNKLDGQIDSKDAEGRYDSAEDLMPPQEILASMAELYLKGGYGLEKNCQLAGELYSQAAEIATNALQGRQAVKYYELADTAYSQDE 2540
            DPW +F ++ ++ ++  RYRYSAI  +W +DEI++K+ +  F  GAMRECFR KKLS    +++H+W  +SNYVAK+Y+  V+R VYFEDV+LQME+KLW EE+NR  PPK++DI Q+ ++E+  R   PL+H+EH++EG Y KYNSNSG+V D  +R TPQAFSHFTFERSGH++I+VDIQGVGDLYTDPQ+HT+ G ++GDGNLG+RGMALFF SH CN IC  +GL+ FD+   E+   D   ++     + +       E+ C            R R+ S      ++     +  V   +  D +  +P+    +M V  G   +   F+++ N         +   S      +  + G   Y  P E ++    + +  +      R+YS+ SD D+     EE  + Y+S + +  +PS             L+++IG SIL +VH  + R HE+GRF         C   + W  +                         S ++H   AA  G LEA++ + +  L +  H+L +  L P++ + + G  +L +AA++GDR SMI +A  +               +   ++W EAV WY  A +  +  +G        G +D  +D  P   +LA +AE+Y +GG  L+ + Q AG+L+++AA+ A  A++GR A +YY  A+ A++  E
Sbjct:  123 DPWAEFHLEEMETERCTRYRYSAITGEWAKDEIFIKVSSQTFGKGAMRECFRAKKLSN--FSHSHNWKSASNYVAKRYMETVDRSVYFEDVRLQMEAKLWGEEFNRHRPPKQVDIMQMCVVEMTTRPGSPLFHLEHYIEGKYTKYNSNSGFVRDDNIRLTPQAFSHFTFERSGHQLIVVDIQGVGDLYTDPQIHTSKGTDFGDGNLGVRGMALFFHSHLCNKICRSMGLTRFDLSPAEIAQLDCTNKLLQSAKTVLR----GFEEQCG---------SPRVRTTSLGHMPVLLSRLSETSSVDESSDTDSIPCSPL----SMGVSVGRSPMGWSFMNEMN---------ETHRSQNTEQQDSENGGDSGY--PSEKRSEGDPVEHHGQGRPIYNRHYSE-SDEDSVRRLTEEKWSFYHSSRSHIHRPSCVAVEVERLNALLLEKKIGKSILGKVHLAMVRYHEAGRF---------CEKDEPWDQI-------------------------SAMYHLETAAMCGELEAIVALGQCYLQLPHHILPEIELEPSEENSQKGFRFLLQAAEAGDRPSMILVARAFDTGLKL--------PSDRAMDWTEAVHWYDSALKMTDYDEG--------GEFDGMQD-EPRYLLLARLAEMYQEGGNNLDADPQRAGDLFTEAADAAMEAMKGRLANQYYMKAEEAWAMME 743
[Close]
BLAST of Elongation factor 2 kinase vs. Ensembl Zebrafish
Match: eef2k (eukaryotic elongation factor 2 kinase [Source:ZFIN;Acc:ZDB-GENE-020916-2])

HSP 1 Score: 301.597 bits (771), Expect = 7.519e-90
Identity = 141/248 (56.85%), Postives = 191/248 (77.02%), Query Frame = 3 
Query:  453 DPWHDFTIDTIKPDKAIRYRYSAIKKKWVQDEIWVKLETLPFDHGAMRECFRLKKLSTTGINNNHDWNFSSNYVAKQYINLVNRDVYFEDVKLQMESKLWAEEYNRQNPPKKIDIFQLSIIELIDRENKPLYHIEHFMEGTYLKYNSNSGYVDDSCLRNTPQAFSHFTFERSGHRIIIVDIQGVGDLYTDPQVHTAXXXXXXXXXXXXXXMALFFSSHRCNPICHYLGLSEFDMHQNELVDNDLDQEI 1196
            DPW +F ++ ++ ++  RYRYSAI  +W +DEI++K+ +  F  GAMRECFR KKLS    +++H+W  +SNYVAK+Y+  V+R VYFEDV+LQME+KLW EE+NR  PPK++DI Q+ ++E+  R   PL+H+EH++EG Y KYNSNSG+V D  +R TPQAFSHFTFERSGH++I+VDIQGVGDLYTDPQ+HT+ G ++GDGNLG+RGMALFF SH CN IC  +GL+ FD+   E+   D   ++
Sbjct:  104 DPWAEFHLEEMETERCTRYRYSAITGEWAKDEIFIKVSSQTFGKGAMRECFRAKKLSN--FSHSHNWKSASNYVAKRYMETVDRSVYFEDVRLQMEAKLWGEEFNRHRPPKQVDIMQMCVVEMTTRPGSPLFHLEHYIEGKYTKYNSNSGFVRDDNIRLTPQAFSHFTFERSGHQLIVVDIQGVGDLYTDPQIHTSKGTDFGDGNLGVRGMALFFHSHLCNKICRSMGLTRFDLSPAEIAQLDCTNKL 349

HSP 2 Score: 102.449 bits (254), Expect = 8.209e-22
Identity = 78/264 (29.55%), Postives = 129/264 (48.86%), Query Frame = 3 
Query: 1755 LDQEIGHSILAQVHHELARLHESGRFVKSKRLAPGCLHHQFWSNLLNENDSPEESEQKSPTNHDLDINWE--SCLFHERHAAQLGCLEAVIVMARYCLNMSGHMLQDCPLPPNQNDIECGLDYLWRAADSGDRRSMIELANLYRKTEYFGEIFNEINKTTLEVNWFEAVKWYKRAFEAVNKLDGQIDSKDAEGRYDSAEDLMPPQEILASMAELYLKGGYGLEKNCQLAGELYSQAAEIATNALQGRQAVKYYELADTAYSQDE 2540
            L+++IG SIL +VH  + R HE+GRF                     E D P                W+  S ++H   AA  G LEA++ + +  L +  H+L +  L P++ + + G  +L +AA++GDR SMI +A  +               +   ++W EAV WY  A +  +  +G        G +D  +D  P   +LA +AE+Y +GG  L+ + Q AG+L+++AA+ A  A++GR A +YY  A+ A++  E
Sbjct:  495 LEKKIGKSILGKVHLAMVRYHEAGRFC--------------------EKDEP----------------WDQISAMYHLETAAMCGELEAIVALGQCYLQLPHHILPEIELEPSEENSQKGFRFLLQAAEAGDRPSMILVARAFDTGLKL--------PSDRAMDWTEAVHWYDSALKMTDYDEG--------GEFDGMQD-EPRYLLLARLAEMYQEGGNNLDADPQRAGDLFTEAADAAMEAMKGRLANQYYMKAEEAWAMME 705
[Close]
BLAST of Elongation factor 2 kinase vs. Ensembl Zebrafish
Match: trpm6 (transient receptor potential cation channel, subfamily M, member 6 [Source:ZFIN;Acc:ZDB-GENE-111212-1])

HSP 1 Score: 57.7658 bits (138), Expect = 7.147e-8
Identity = 44/156 (28.21%), Postives = 76/156 (48.72%), Query Frame = 3 
Query:  714 FEDVKLQMESKLWAEEYNRQNP---PKKIDIFQLSIIELIDRENKPLYHIEHFMEGTYLKYNSNSG--YVDDSCLRNTPQAFSHFTFERSGHRIIIVDIQGVGDLYTDPQV------HTAXXXXXXXXXXXXXXMALFFSSHRCNPICHYLGLSEF 1148
              +++ Q  ++   + +N+  P   P       +S++    R +     +E+ M G + KYN+N+G   +  S L  T  AFSH+T+E +   ++++D+QGVG   TDP +       +   + +G  NLG   +  F   H CN  C  LGLS+ 
Sbjct: 1702 LREIQQQRAAQKLMQRFNQVKPSSVPHSPRFLDVSLLHW--RSDGQWLTVENNMSGHFRKYNNNTGEEILPSSGLEETILAFSHWTYEYTNKELLVLDLQGVGADLTDPSLIRVDDKSSPGEMAFGPANLGDDAIQSFVLKHTCNSCCKKLGLSDL 1855
[Close]
BLAST of Elongation factor 2 kinase vs. Ensembl Zebrafish
Match: trpm7 (transient receptor potential cation channel, subfamily M, member 7 [Source:ZFIN;Acc:ZDB-GENE-021115-2])

HSP 1 Score: 56.225 bits (134), Expect = 1.361e-7
Identity = 37/120 (30.83%), Postives = 61/120 (50.83%), Query Frame = 3 
Query:  846 YHIEHFMEGTYLKYNSNSG--YVDDSCLRNTPQAFSHFTFERSGHRIIIVDIQGVGDLYTDPQVHTAXXXXXXXXXXXXXXMA-----LFFSSHRCNPICHYLGLSEFDMHQNELVDNDL 1184
            + IE  + G + K+N+N+G   V  + L  T  AFSH+T+E +   ++++D+QGVG++ TDP V  +      D   G   +       F + H CN  C  L L   D+ +N+   + L
Sbjct:  458 FAIEECITGDFRKFNNNNGDEIVPTNLLEETMLAFSHWTYEYTRGELLVLDLQGVGEILTDPSVIKSGEKGSYDMIFGPANLGDDAIRNFRAKHHCNSCCRKLKLP--DLKRNDYTPDKL 575
[Close]
BLAST of Elongation factor 2 kinase vs. Ensembl Zebrafish
Match: trpm7 (transient receptor potential cation channel, subfamily M, member 7 [Source:ZFIN;Acc:ZDB-GENE-021115-2])

HSP 1 Score: 55.8398 bits (133), Expect = 2.547e-7
Identity = 37/120 (30.83%), Postives = 61/120 (50.83%), Query Frame = 3 
Query:  846 YHIEHFMEGTYLKYNSNSG--YVDDSCLRNTPQAFSHFTFERSGHRIIIVDIQGVGDLYTDPQVHTAXXXXXXXXXXXXXXMA-----LFFSSHRCNPICHYLGLSEFDMHQNELVDNDL 1184
            + IE  + G + K+N+N+G   V  + L  T  AFSH+T+E +   ++++D+QGVG++ TDP V  +      D   G   +       F + H CN  C  L L   D+ +N+   + L
Sbjct: 1624 FAIEECITGDFRKFNNNNGDEIVPTNLLEETMLAFSHWTYEYTRGELLVLDLQGVGEILTDPSVIKSGEKGSYDMIFGPANLGDDAIRNFRAKHHCNSCCRKLKLP--DLKRNDYTPDKL 1741
[Close]
BLAST of Elongation factor 2 kinase vs. Ensembl Xenopus
Match: neu4 (neuraminidase 4 (sialidase) [Source:Xenbase;Acc:XB-GENE-959717])

HSP 1 Score: 374.785 bits (961), Expect = 5.262e-117
Identity = 259/705 (36.74%), Postives = 373/705 (52.91%), Query Frame = 3 
Query:  453 DPWHDFTIDTIKPDKAIRYRYSAIKKKWVQDEIWVKLETLPFDHGAMRECFRLKKLSTTGINNNHDWNFSSNYVAKQYINLVNRDVYFEDVKLQMESKLWAEEYNRQNPPKKIDIFQLSIIELIDRENKPLYHIEHFMEGTYLKYNSNSGYVDDSCLRNTPQAFSHFTFERSGHRIIIVDIQGVGDLYTDPQVHTAXXXXXXXXXXXXXXMALFFSSHRCNPICHYLGLSEFDMHQNELVDNDLDQEIADHDISTISIDALPEEDSCAFSSKSYNEIKKRNRSISFKMSGTVIRDGRTSPCVTSPAFLDQLFPAPIDLIRAMSVDSGVQSVS--TP----FVSQGNFMTXXXXXXXXXXXXXXXXXXXXHSGLGAYHHPYEIKTNLSQIINSRKLFRRRQRNYSDGSDIDASLVSYEEHLAVYYSMKENQKPSSAT------HPTNLDQEIGHSILAQVHHELARLHESGRFVKSKRLAPGCLHHQFWSNLLNENDSPEESEQKSPTNHDLDINWESCLFHERHAAQLGCLEAVIVMARYCLNMSGHMLQDCPLPPNQNDIECGLDYLWRAADSGDRRSMIELANLYRKTEYFGEIFNEINKTTLEVNWFEAVKWYKRAFEAVNKLDGQIDSKDAEGRYDSAEDLMPPQEILASMAELYLKGGYGLEKNCQLAGELYSQAAEIATNALQGRQAVKYYELADTAYS 2531
            DPW +F ++ I+ + AIR+RY+A+  +WVQD++ +K+ +  F  GAMREC+R KKLS    ++   W  + NYV+K+Y+  V+RDVYFEDV+LQME+KLW EEYNR  PPK++DI Q+ IIE+ DR  KPL+H+EH++EG Y+KYNSNSG+V D  +R TPQAFSHFTFERSGH++I+VD+QGVGDLYTDPQ+HT  G ++GDGNLG+RGMALFF SH CN IC  +GL+ FD                      IS       D+C   SK     +   R I  K     +R    +   + P  L +L     D +  M+ DS   S S  TP    F S G  + + +    +  ++ +       +G G    P E ++   ++    ++    +R +   S+     VS E+    + S     +PS         +   L+++IG SIL +VH  + R HE GRF         C   Q W                           ES +FH  HAA  G LEA+I +         H+L D  +   +++   G +YL  AA++GDR SMI +A  +      G   + I       +W EA+ WY  A    +  +G        G YD  +D  P   +LA  AE+ L GG+ L+K+ Q +G+LY++AAE A  A++GR A +YY+ A+ A++
Sbjct:   95 DPWAEFHLEDIETEHAIRHRYNAVSGQWVQDDVLIKMASQAFGRGAMRECYRTKKLSN--FSHKQQWKSAYNYVSKRYLETVDRDVYFEDVRLQMEAKLWGEEYNRHKPPKQVDIMQMCIIEMKDRPGKPLFHLEHYIEGKYIKYNSNSGFVRDDNIRLTPQAFSHFTFERSGHQLIVVDVQGVGDLYTDPQIHTESGTDFGDGNLGVRGMALFFHSHACNRICKSMGLTPFD----------------------ISAKEKAVLDNC---SKMLQTAQTVVRGIEEKCGSNRVR----TMSGSRPPLLSRLSENSGDDMSDMAFDSLPSSPSPVTPHGHRFDSHGWPIFNEVDNLLNEENNNLDNHRDSENG-GDSGCPSEKRSESDEL--EHRIHNVGRRRFESESEDSFGKVSVEKWNQFHASRVHVHRPSCVAFEVERLNALELEKKIGKSILGKVHLAMVRYHEGGRF---------CEKDQEWDQ-------------------------ESAIFHLEHAAHCGELEAIIGLGLMYSQSPHHILTDVSVQDTEDNRIKGFNYLLMAAEAGDRPSMIHVARAFDTGVNLGS--DRIK------DWQEALFWYDSALNMTDYDEG--------GEYDGTQD-EPKYLLLAREAEMLLTGGFNLQKDPQRSGDLYTEAAEAAMEAMKGRLANQYYQKAEEAWA 714
[Close]
BLAST of Elongation factor 2 kinase vs. Ensembl Xenopus
Match: neu4 (neuraminidase 4 (sialidase) [Source:Xenbase;Acc:XB-GENE-959717])

HSP 1 Score: 298.516 bits (763), Expect = 6.575e-92
Identity = 143/244 (58.61%), Postives = 191/244 (78.28%), Query Frame = 3 
Query:  453 DPWHDFTIDTIKPDKAIRYRYSAIKKKWVQDEIWVKLETLPFDHGAMRECFRLKKLSTTGINNNHDWNFSSNYVAKQYINLVNRDVYFEDVKLQMESKLWAEEYNRQNPPKKIDIFQLSIIELIDRENKPLYHIEHFMEGTYLKYNSNSGYVDDSCLRNTPQAFSHFTFERSGHRIIIVDIQGVGDLYTDPQVHTAXXXXXXXXXXXXXXMALFFSSHRCNPICHYLGLSEFDMHQNE--LVDN 1178
            DPW +F ++ I+ + AIR+RY+A+  +WVQD++ +K+ +  F  GAMREC+R KKLS    ++   W  + NYV+K+Y+  V+RDVYFEDV+LQME+KLW EEYNR  PPK++DI Q+ IIE+ DR  KPL+H+EH++EG Y+KYNSNSG+V D  +R TPQAFSHFTFERSGH++I+VD+QGVGDLYTDPQ+HT  G ++GDGNLG+RGMALFF SH CN IC  +GL+ FD+   E  ++DN
Sbjct:   95 DPWAEFHLEDIETEHAIRHRYNAVSGQWVQDDVLIKMASQAFGRGAMRECYRTKKLSN--FSHKQQWKSAYNYVSKRYLETVDRDVYFEDVRLQMEAKLWGEEYNRHKPPKQVDIMQMCIIEMKDRPGKPLFHLEHYIEGKYIKYNSNSGFVRDDNIRLTPQAFSHFTFERSGHQLIVVDVQGVGDLYTDPQIHTESGTDFGDGNLGVRGMALFFHSHACNRICKSMGLTPFDISAKEKAVLDN 336
[Close]
BLAST of Elongation factor 2 kinase vs. Ensembl Xenopus
Match: neu4 (neuraminidase 4 (sialidase) [Source:Xenbase;Acc:XB-GENE-959717])

HSP 1 Score: 298.516 bits (763), Expect = 1.113e-88
Identity = 143/244 (58.61%), Postives = 191/244 (78.28%), Query Frame = 3 
Query:  453 DPWHDFTIDTIKPDKAIRYRYSAIKKKWVQDEIWVKLETLPFDHGAMRECFRLKKLSTTGINNNHDWNFSSNYVAKQYINLVNRDVYFEDVKLQMESKLWAEEYNRQNPPKKIDIFQLSIIELIDRENKPLYHIEHFMEGTYLKYNSNSGYVDDSCLRNTPQAFSHFTFERSGHRIIIVDIQGVGDLYTDPQVHTAXXXXXXXXXXXXXXMALFFSSHRCNPICHYLGLSEFDMHQNE--LVDN 1178
            DPW +F ++ I+ + AIR+RY+A+  +WVQD++ +K+ +  F  GAMREC+R KKLS    ++   W  + NYV+K+Y+  V+RDVYFEDV+LQME+KLW EEYNR  PPK++DI Q+ IIE+ DR  KPL+H+EH++EG Y+KYNSNSG+V D  +R TPQAFSHFTFERSGH++I+VD+QGVGDLYTDPQ+HT  G ++GDGNLG+RGMALFF SH CN IC  +GL+ FD+   E  ++DN
Sbjct:  112 DPWAEFHLEDIETEHAIRHRYNAVSGQWVQDDVLIKMASQAFGRGAMRECYRTKKLSN--FSHKQQWKSAYNYVSKRYLETVDRDVYFEDVRLQMEAKLWGEEYNRHKPPKQVDIMQMCIIEMKDRPGKPLFHLEHYIEGKYIKYNSNSGFVRDDNIRLTPQAFSHFTFERSGHQLIVVDVQGVGDLYTDPQIHTESGTDFGDGNLGVRGMALFFHSHACNRICKSMGLTPFDISAKEKAVLDN 353

HSP 2 Score: 94.3597 bits (233), Expect = 3.939e-19
Identity = 77/250 (30.80%), Postives = 114/250 (45.60%), Query Frame = 3 
Query: 1782 LAQVHHELARLHESGRFVKSKRLAPGCLHHQFWSNLLNENDSPEESEQKSPTNHDLDINWESCLFHERHAAQLGCLEAVIVMARYCLNMSGHMLQDCPLPPNQNDIECGLDYLWRAADSGDRRSMIELANLYRKTEYFGEIFNEINKTTLEVNWFEAVKWYKRAFEAVNKLDGQIDSKDAEGRYDSAEDLMPPQEILASMAELYLKGGYGLEKNCQLAGELYSQAAEIATNALQGRQAVKYYELADTAYS 2531
              +VH  + R HE GRF         C   Q W                           ES +FH  HAA  G LEA+I +         H+L D  +   +++   G +YL  AA++GDR SMI +A  +      G   + I       +W EA+ WY  A    +  +G        G YD  +D  P   +LA  AE+ L GG+ L+K+ Q +G+LY++AAE A  A++GR A +YY+ A+ A++
Sbjct:  488 FGKVHLAMVRYHEGGRF---------CEKDQEWDQ-------------------------ESAIFHLEHAAHCGELEAIIGLGLMYSQSPHHILTDVSVQDTEDNRIKGFNYLLMAAEAGDRPSMIHVARAFDTGVNLGS--DRIK------DWQEALFWYDSALNMTDYDEG--------GEYDGTQD-EPKYLLLAREAEMLLTGGFNLQKDPQRSGDLYTEAAEAAMEAMKGRLANQYYQKAEEAWA 686
[Close]
BLAST of Elongation factor 2 kinase vs. Ensembl Xenopus
Match: neu4 (neuraminidase 4 (sialidase) [Source:Xenbase;Acc:XB-GENE-959717])

HSP 1 Score: 298.516 bits (763), Expect = 1.571e-88
Identity = 143/244 (58.61%), Postives = 191/244 (78.28%), Query Frame = 3 
Query:  453 DPWHDFTIDTIKPDKAIRYRYSAIKKKWVQDEIWVKLETLPFDHGAMRECFRLKKLSTTGINNNHDWNFSSNYVAKQYINLVNRDVYFEDVKLQMESKLWAEEYNRQNPPKKIDIFQLSIIELIDRENKPLYHIEHFMEGTYLKYNSNSGYVDDSCLRNTPQAFSHFTFERSGHRIIIVDIQGVGDLYTDPQVHTAXXXXXXXXXXXXXXMALFFSSHRCNPICHYLGLSEFDMHQNE--LVDN 1178
            DPW +F ++ I+ + AIR+RY+A+  +WVQD++ +K+ +  F  GAMREC+R KKLS    ++   W  + NYV+K+Y+  V+RDVYFEDV+LQME+KLW EEYNR  PPK++DI Q+ IIE+ DR  KPL+H+EH++EG Y+KYNSNSG+V D  +R TPQAFSHFTFERSGH++I+VD+QGVGDLYTDPQ+HT  G ++GDGNLG+RGMALFF SH CN IC  +GL+ FD+   E  ++DN
Sbjct:   95 DPWAEFHLEDIETEHAIRHRYNAVSGQWVQDDVLIKMASQAFGRGAMRECYRTKKLSN--FSHKQQWKSAYNYVSKRYLETVDRDVYFEDVRLQMEAKLWGEEYNRHKPPKQVDIMQMCIIEMKDRPGKPLFHLEHYIEGKYIKYNSNSGFVRDDNIRLTPQAFSHFTFERSGHQLIVVDVQGVGDLYTDPQIHTESGTDFGDGNLGVRGMALFFHSHACNRICKSMGLTPFDISAKEKAVLDN 336

HSP 2 Score: 105.916 bits (263), Expect = 7.897e-23
Identity = 83/259 (32.05%), Postives = 123/259 (47.49%), Query Frame = 3 
Query: 1755 LDQEIGHSILAQVHHELARLHESGRFVKSKRLAPGCLHHQFWSNLLNENDSPEESEQKSPTNHDLDINWESCLFHERHAAQLGCLEAVIVMARYCLNMSGHMLQDCPLPPNQNDIECGLDYLWRAADSGDRRSMIELANLYRKTEYFGEIFNEINKTTLEVNWFEAVKWYKRAFEAVNKLDGQIDSKDAEGRYDSAEDLMPPQEILASMAELYLKGGYGLEKNCQLAGELYSQAAEIATNALQGRQAVKYYELADTAYS 2531
            L+++IG SIL +VH  + R HE GRF         C   Q W                           ES +FH  HAA  G LEA+I +         H+L D  +   +++   G +YL  AA++GDR SMI +A  +      G   + I       +W EA+ WY  A    +  +G        G YD  +D  P   +LA  AE+ L GG+ L+K+ Q +G+LY++AAE A  A++GR A +YY+ A+ A++
Sbjct:  500 LEKKIGKSILGKVHLAMVRYHEGGRF---------CEKDQEWDQ-------------------------ESAIFHLEHAAHCGELEAIIGLGLMYSQSPHHILTDVSVQDTEDNRIKGFNYLLMAAEAGDRPSMIHVARAFDTGVNLGS--DRIK------DWQEALFWYDSALNMTDYDEG--------GEYDGTQD-EPKYLLLAREAEMLLTGGFNLQKDPQRSGDLYTEAAEAAMEAMKGRLANQYYQKAEEAWA 707
[Close]
BLAST of Elongation factor 2 kinase vs. Ensembl Xenopus
Match: neu4 (neuraminidase 4 (sialidase) [Source:Xenbase;Acc:XB-GENE-959717])

HSP 1 Score: 297.36 bits (760), Expect = 1.693e-88
Identity = 143/244 (58.61%), Postives = 191/244 (78.28%), Query Frame = 3 
Query:  453 DPWHDFTIDTIKPDKAIRYRYSAIKKKWVQDEIWVKLETLPFDHGAMRECFRLKKLSTTGINNNHDWNFSSNYVAKQYINLVNRDVYFEDVKLQMESKLWAEEYNRQNPPKKIDIFQLSIIELIDRENKPLYHIEHFMEGTYLKYNSNSGYVDDSCLRNTPQAFSHFTFERSGHRIIIVDIQGVGDLYTDPQVHTAXXXXXXXXXXXXXXMALFFSSHRCNPICHYLGLSEFDMHQNE--LVDN 1178
            DPW +F ++ I+ + AIR+RY+A+  +WVQD++ +K+ +  F  GAMREC+R KKLS    ++   W  + NYV+K+Y+  V+RDVYFEDV+LQME+KLW EEYNR  PPK++DI Q+ IIE+ DR  KPL+H+EH++EG Y+KYNSNSG+V D  +R TPQAFSHFTFERSGH++I+VD+QGVGDLYTDPQ+HT  G ++GDGNLG+RGMALFF SH CN IC  +GL+ FD+   E  ++DN
Sbjct:   95 DPWAEFHLEDIETEHAIRHRYNAVSGQWVQDDVLIKMASQAFGRGAMRECYRTKKLSN--FSHKQQWKSAYNYVSKRYLETVDRDVYFEDVRLQMEAKLWGEEYNRHKPPKQVDIMQMCIIEMKDRPGKPLFHLEHYIEGKYIKYNSNSGFVRDDNIRLTPQAFSHFTFERSGHQLIVVDVQGVGDLYTDPQIHTESGTDFGDGNLGVRGMALFFHSHACNRICKSMGLTPFDISAKEKAVLDN 336

HSP 2 Score: 77.411 bits (189), Expect = 6.069e-14
Identity = 76/259 (29.34%), Postives = 108/259 (41.70%), Query Frame = 3 
Query: 1755 LDQEIGHSILAQVHHELARLHESGRFVKSKRLAPGCLHHQFWSNLLNENDSPEESEQKSPTNHDLDINWESCLFHERHAAQLGCLEAVIVMARYCLNMSGHMLQDCPLPPNQNDIECGLDYLWRAADSGDRRSMIELANLYRKTEYFGEIFNEINKTTLEVNWFEAVKWYKRAFEAVNKLDGQIDSKDAEGRYDSAEDLMPPQEILASMAELYLKGGYGLEKNCQLAGELYSQAAEIATNALQGRQAVKYYELADTAYS 2531
            L+++IG SIL +VH  + R HE GRF         C   Q W                           ES +FH  HAA  G LEA+I +         H+L D    P   +I C L             SMI+                         +W EA+ WY  A    +  +G        G YD  +D  P   +LA  AE+ L GG+ L+K+ Q +G+LY++AAE A  A++GR A +YY+ A+ A++
Sbjct:  500 LEKKIGKSILGKVHLAMVRYHEGGRF---------CEKDQEWDQ-------------------------ESAIFHLEHAAHCGELEAIIGLGLMYSQSPHHILTD----PYTKNIFCFL------------CSMIK-------------------------DWQEALFWYDSALNMTDYDEG--------GEYDGTQD-EPKYLLLAREAEMLLTGGFNLQKDPQRSGDLYTEAAEAAMEAMKGRLANQYYQKAEEAWA 674
[Close]
BLAST of Elongation factor 2 kinase vs. Ensembl Mouse
Match: Eef2k (eukaryotic elongation factor-2 kinase [Source:MGI Symbol;Acc:MGI:1195261])

HSP 1 Score: 298.13 bits (762), Expect = 2.011e-88
Identity = 151/263 (57.41%), Postives = 194/263 (73.76%), Query Frame = 3 
Query:  384 TISPALKRWFRAVSK--ICKHDDDIDPWHDFTIDTIKPDKAIRYRYSAIKKKWVQDEIWVKLETLPFDHGAMRECFRLKKLSTTGINNNHDWNFSSNYVAKQYINLVNRDVYFEDVKLQMESKLWAEEYNRQNPPKKIDIFQLSIIELIDRENKPLYHIEHFMEGTYLKYNSNSGYVDDSCLRNTPQAFSHFTFERSGHRIIIVDIQGVGDLYTDPQVHTAXXXXXXXXXXXXXXMALFFSSHRCNPICHYLGLSEFDMHQNE 1166
            T SPA    F+   K  I K     DPW +F ++ I  + A R+RY+A+  +W++DE+ +K+ + PF  GAMRECFR KKLS     +   W  +SNYVAK+YI  V+R VYFEDV+LQME+KLW E+YNR  PPK++DI Q+ IIEL DR  +PL+H+EH++EG Y+KYNSNSG+V D  +R TPQAFSHFTFERSGH++I+VDIQGVGDLYTDPQ+HT  G ++GDGNLG+RGMALFF SH CN IC  +GL+ FD+   E
Sbjct:   71 TGSPASSFHFKEAWKHAIEKAKHMPDPWAEFHLEDIATEHATRHRYNAVTGEWLKDEVLIKMASQPFGRGAMRECFRTKKLSN--FLHAQQWKGASNYVAKRYIEPVDRSVYFEDVQLQMEAKLWGEDYNRHKPPKQVDIMQMCIIELKDRPGQPLFHLEHYIEGKYIKYNSNSGFVRDDNIRLTPQAFSHFTFERSGHQLIVVDIQGVGDLYTDPQIHTEKGTDFGDGNLGVRGMALFFYSHACNRICQSMGLTPFDLSPRE 331

HSP 2 Score: 121.709 bits (304), Expect = 7.542e-28
Identity = 90/269 (33.46%), Postives = 129/269 (47.96%), Query Frame = 3 
Query: 1752 NLDQEIGHSILAQVHHELARLHESGRFVKSKRLAPGCLHHQFWSNLLNENDSPEESEQKSPTNHDLDINWESCLFHERHAAQLGCLEAVIVMARYCLNMSGHMLQDCPLPPNQNDIECGLDYLWRAADSGDRRSMIELANLYRKTEYFGEIFNEINKTTLEV------NWFEAVKWYKRAFEAVNKLDGQIDSKDAEGRYDSAEDLMPPQEILASMAELYLKGGYGLEKNCQLAGELYSQAAEIATNALQGRQAVKYYELADTAYSQDE 2540
            +L ++IG S+L +VH  + R HE GRF         C   + W                           ES +FH  HAA LG LEA++ +      +  H+L D  L   + +   G DYL +AA++GDR SMI +A  +               T L +      +W EA+ WY  A E  +  +G        G YD  +D  P   +LA  AE+ L GG+GL+KN Q +G+LY+QAAE A  A++GR A +YYE A+ A++Q E
Sbjct:  512 DLGRKIGKSVLGKVHLAMVRYHEGGRF---------CEKDEEWDR-------------------------ESAIFHLEHAADLGELEAIVGLGLMYSQLPHHILADVSLKETEENKTKGFDYLLKAAEAGDRHSMILVARAF--------------DTGLNLSPDRCQDWSEALHWYNTALETTDCDEG--------GEYDGIQD-EPQYALLAREAEMLLTGGFGLDKNPQRSGDLYTQAAEAAMEAMKGRLANQYYEKAEEAWAQME 723
[Close]
BLAST of Elongation factor 2 kinase vs. Ensembl Mouse
Match: Eef2k (eukaryotic elongation factor-2 kinase [Source:MGI Symbol;Acc:MGI:1195261])

HSP 1 Score: 298.13 bits (762), Expect = 2.011e-88
Identity = 151/263 (57.41%), Postives = 194/263 (73.76%), Query Frame = 3 
Query:  384 TISPALKRWFRAVSK--ICKHDDDIDPWHDFTIDTIKPDKAIRYRYSAIKKKWVQDEIWVKLETLPFDHGAMRECFRLKKLSTTGINNNHDWNFSSNYVAKQYINLVNRDVYFEDVKLQMESKLWAEEYNRQNPPKKIDIFQLSIIELIDRENKPLYHIEHFMEGTYLKYNSNSGYVDDSCLRNTPQAFSHFTFERSGHRIIIVDIQGVGDLYTDPQVHTAXXXXXXXXXXXXXXMALFFSSHRCNPICHYLGLSEFDMHQNE 1166
            T SPA    F+   K  I K     DPW +F ++ I  + A R+RY+A+  +W++DE+ +K+ + PF  GAMRECFR KKLS     +   W  +SNYVAK+YI  V+R VYFEDV+LQME+KLW E+YNR  PPK++DI Q+ IIEL DR  +PL+H+EH++EG Y+KYNSNSG+V D  +R TPQAFSHFTFERSGH++I+VDIQGVGDLYTDPQ+HT  G ++GDGNLG+RGMALFF SH CN IC  +GL+ FD+   E
Sbjct:   71 TGSPASSFHFKEAWKHAIEKAKHMPDPWAEFHLEDIATEHATRHRYNAVTGEWLKDEVLIKMASQPFGRGAMRECFRTKKLSN--FLHAQQWKGASNYVAKRYIEPVDRSVYFEDVQLQMEAKLWGEDYNRHKPPKQVDIMQMCIIELKDRPGQPLFHLEHYIEGKYIKYNSNSGFVRDDNIRLTPQAFSHFTFERSGHQLIVVDIQGVGDLYTDPQIHTEKGTDFGDGNLGVRGMALFFYSHACNRICQSMGLTPFDLSPRE 331

HSP 2 Score: 121.709 bits (304), Expect = 7.542e-28
Identity = 90/269 (33.46%), Postives = 129/269 (47.96%), Query Frame = 3 
Query: 1752 NLDQEIGHSILAQVHHELARLHESGRFVKSKRLAPGCLHHQFWSNLLNENDSPEESEQKSPTNHDLDINWESCLFHERHAAQLGCLEAVIVMARYCLNMSGHMLQDCPLPPNQNDIECGLDYLWRAADSGDRRSMIELANLYRKTEYFGEIFNEINKTTLEV------NWFEAVKWYKRAFEAVNKLDGQIDSKDAEGRYDSAEDLMPPQEILASMAELYLKGGYGLEKNCQLAGELYSQAAEIATNALQGRQAVKYYELADTAYSQDE 2540
            +L ++IG S+L +VH  + R HE GRF         C   + W                           ES +FH  HAA LG LEA++ +      +  H+L D  L   + +   G DYL +AA++GDR SMI +A  +               T L +      +W EA+ WY  A E  +  +G        G YD  +D  P   +LA  AE+ L GG+GL+KN Q +G+LY+QAAE A  A++GR A +YYE A+ A++Q E
Sbjct:  512 DLGRKIGKSVLGKVHLAMVRYHEGGRF---------CEKDEEWDR-------------------------ESAIFHLEHAADLGELEAIVGLGLMYSQLPHHILADVSLKETEENKTKGFDYLLKAAEAGDRHSMILVARAF--------------DTGLNLSPDRCQDWSEALHWYNTALETTDCDEG--------GEYDGIQD-EPQYALLAREAEMLLTGGFGLDKNPQRSGDLYTQAAEAAMEAMKGRLANQYYEKAEEAWAQME 723
[Close]
BLAST of Elongation factor 2 kinase vs. Ensembl Mouse
Match: Eef2k (eukaryotic elongation factor-2 kinase [Source:MGI Symbol;Acc:MGI:1195261])

HSP 1 Score: 298.13 bits (762), Expect = 2.011e-88
Identity = 151/263 (57.41%), Postives = 194/263 (73.76%), Query Frame = 3 
Query:  384 TISPALKRWFRAVSK--ICKHDDDIDPWHDFTIDTIKPDKAIRYRYSAIKKKWVQDEIWVKLETLPFDHGAMRECFRLKKLSTTGINNNHDWNFSSNYVAKQYINLVNRDVYFEDVKLQMESKLWAEEYNRQNPPKKIDIFQLSIIELIDRENKPLYHIEHFMEGTYLKYNSNSGYVDDSCLRNTPQAFSHFTFERSGHRIIIVDIQGVGDLYTDPQVHTAXXXXXXXXXXXXXXMALFFSSHRCNPICHYLGLSEFDMHQNE 1166
            T SPA    F+   K  I K     DPW +F ++ I  + A R+RY+A+  +W++DE+ +K+ + PF  GAMRECFR KKLS     +   W  +SNYVAK+YI  V+R VYFEDV+LQME+KLW E+YNR  PPK++DI Q+ IIEL DR  +PL+H+EH++EG Y+KYNSNSG+V D  +R TPQAFSHFTFERSGH++I+VDIQGVGDLYTDPQ+HT  G ++GDGNLG+RGMALFF SH CN IC  +GL+ FD+   E
Sbjct:   71 TGSPASSFHFKEAWKHAIEKAKHMPDPWAEFHLEDIATEHATRHRYNAVTGEWLKDEVLIKMASQPFGRGAMRECFRTKKLSN--FLHAQQWKGASNYVAKRYIEPVDRSVYFEDVQLQMEAKLWGEDYNRHKPPKQVDIMQMCIIELKDRPGQPLFHLEHYIEGKYIKYNSNSGFVRDDNIRLTPQAFSHFTFERSGHQLIVVDIQGVGDLYTDPQIHTEKGTDFGDGNLGVRGMALFFYSHACNRICQSMGLTPFDLSPRE 331

HSP 2 Score: 121.709 bits (304), Expect = 7.542e-28
Identity = 90/269 (33.46%), Postives = 129/269 (47.96%), Query Frame = 3 
Query: 1752 NLDQEIGHSILAQVHHELARLHESGRFVKSKRLAPGCLHHQFWSNLLNENDSPEESEQKSPTNHDLDINWESCLFHERHAAQLGCLEAVIVMARYCLNMSGHMLQDCPLPPNQNDIECGLDYLWRAADSGDRRSMIELANLYRKTEYFGEIFNEINKTTLEV------NWFEAVKWYKRAFEAVNKLDGQIDSKDAEGRYDSAEDLMPPQEILASMAELYLKGGYGLEKNCQLAGELYSQAAEIATNALQGRQAVKYYELADTAYSQDE 2540
            +L ++IG S+L +VH  + R HE GRF         C   + W                           ES +FH  HAA LG LEA++ +      +  H+L D  L   + +   G DYL +AA++GDR SMI +A  +               T L +      +W EA+ WY  A E  +  +G        G YD  +D  P   +LA  AE+ L GG+GL+KN Q +G+LY+QAAE A  A++GR A +YYE A+ A++Q E
Sbjct:  512 DLGRKIGKSVLGKVHLAMVRYHEGGRF---------CEKDEEWDR-------------------------ESAIFHLEHAADLGELEAIVGLGLMYSQLPHHILADVSLKETEENKTKGFDYLLKAAEAGDRHSMILVARAF--------------DTGLNLSPDRCQDWSEALHWYNTALETTDCDEG--------GEYDGIQD-EPQYALLAREAEMLLTGGFGLDKNPQRSGDLYTQAAEAAMEAMKGRLANQYYEKAEEAWAQME 723
[Close]
BLAST of Elongation factor 2 kinase vs. Ensembl Mouse
Match: Eef2k (eukaryotic elongation factor-2 kinase [Source:MGI Symbol;Acc:MGI:1195261])

HSP 1 Score: 80.1073 bits (196), Expect = 1.110e-16
Identity = 57/144 (39.58%), Postives = 82/144 (56.94%), Query Frame = 3 
Query: 2106 GLDYLWRAADSGDRRSMIELANLYRKTEYFGEIFNEINKTTLEV-NWFEAVKWYKRAFEAVNKLDGQIDSKDAEGRYDSAEDLMPPQEILASMAELYLKGGYGLEKNCQLAGELYSQAAEIATNALQGRQAVKYYELADTAYSQ 2534
            G DYL +AA++GDR SMI +A  +            +N +     +W EA+ WY  A E  +  +G        G YD  +D  P   +LA  AE+ L GG+GL+KN Q +G+LY+QAAE A  A++GR A +YYE A+ A++Q
Sbjct:   57 GFDYLLKAAEAGDRHSMILVARAFDTG---------LNLSPDRCQDWSEALHWYNTALETTDCDEG--------GEYDGIQD-EPQYALLAREAEMLLTGGFGLDKNPQRSGDLYTQAAEAAMEAMKGRLANQYYEKAEEAWAQ 182
[Close]
BLAST of Elongation factor 2 kinase vs. Ensembl Mouse
Match: Eef2k (eukaryotic elongation factor-2 kinase [Source:MGI Symbol;Acc:MGI:1195261])

HSP 1 Score: 72.7886 bits (177), Expect = 2.062e-14
Identity = 37/91 (40.66%), Postives = 54/91 (59.34%), Query Frame = 3 
Query:  357 NSPDSDRTDTISPALKRWFRAVSK--ICKHDDDIDPWHDFTIDTIKPDKAIRYRYSAIKKKWVQDEIWVKLETLPFDHGAMRECFRLKKLS 623
            N   ++   T SPA    F+   K  I K     DPW +F ++ I  + A R+RY+A+  +W++DE+ +K+ + PF  GAMRECFR KKLS
Sbjct:   62 NLTKTECGSTGSPASSFHFKEAWKHAIEKAKHMPDPWAEFHLEDIATEHATRHRYNAVTGEWLKDEVLIKMASQPFGRGAMRECFRTKKLS 152
[Close]
BLAST of Elongation factor 2 kinase vs. UniProt/SwissProt
Match: sp|O00418|EF2K_HUMAN (Eukaryotic elongation factor 2 kinase OS=Homo sapiens OX=9606 GN=EEF2K PE=1 SV=2)

HSP 1 Score: 303.908 bits (777), Expect = 1.134e-89
Identity = 151/253 (59.68%), Postives = 192/253 (75.89%), Query Frame = 3 
Query:  408 WFRAVSKICKHDDDIDPWHDFTIDTIKPDKAIRYRYSAIKKKWVQDEIWVKLETLPFDHGAMRECFRLKKLSTTGINNNHDWNFSSNYVAKQYINLVNRDVYFEDVKLQMESKLWAEEYNRQNPPKKIDIFQLSIIELIDRENKPLYHIEHFMEGTYLKYNSNSGYVDDSCLRNTPQAFSHFTFERSGHRIIIVDIQGVGDLYTDPQVHTAXXXXXXXXXXXXXXMALFFSSHRCNPICHYLGLSEFDMHQNE 1166
            W  A+ K  KH  D  PW +F ++ I  ++A R+RY+A+  +W+ DE+ +K+ + PF  GAMRECFR KKLS     +   W  +SNYVAK+YI  V+RDVYFEDV+LQME+KLW EEYNR  PPK++DI Q+ IIEL DR  KPL+H+EH++EG Y+KYNSNSG+V D  +R TPQAFSHFTFERSGH++I+VDIQGVGDLYTDPQ+HT  G ++GDGNLG+RGMALFF SH CN IC  +GL+ FD+   E
Sbjct:   85 WKHAIQK-AKHMPD--PWAEFHLEDIATERATRHRYNAVTGEWLDDEVLIKMASQPFGRGAMRECFRTKKLSN--FLHAQQWKGASNYVAKRYIEPVDRDVYFEDVRLQMEAKLWGEEYNRHKPPKQVDIMQMCIIELKDRPGKPLFHLEHYIEGKYIKYNSNSGFVRDDNIRLTPQAFSHFTFERSGHQLIVVDIQGVGDLYTDPQIHTETGTDFGDGNLGVRGMALFFYSHACNRICESMGLAPFDLSPRE 332

HSP 2 Score: 123.635 bits (309), Expect = 1.437e-27
Identity = 88/263 (33.46%), Postives = 129/263 (49.05%), Query Frame = 3 
Query: 1752 NLDQEIGHSILAQVHHELARLHESGRFVKSKRLAPGCLHHQFWSNLLNENDSPEESEQKSPTNHDLDINWESCLFHERHAAQLGCLEAVIVMARYCLNMSGHMLQDCPLPPNQNDIECGLDYLWRAADSGDRRSMIELANLYRKTEYFGEIFNEINKTTLEVNWFEAVKWYKRAFEAVNKLDGQIDSKDAEGRYDSAEDLMPPQEILASMAELYLKGGYGLEKNCQLAGELYSQAAEIATNALQGRQAVKYYELADTAYSQDE 2540
            +L+++IG SIL +VH  + R HE GRF         C   + W                           ES +FH  HAA LG LEA++ +      +  H+L D  L   + +   G DYL +AA++GDR+SMI +A  +   +       +        +W EA+ WY  A E  +  +G        G YD  +D  P   +LA  AE+   GGYGLEK+ Q +G+LY+QAAE A  A++GR A +YY+ A+ A++Q E
Sbjct:  513 DLEKKIGKSILGKVHLAMVRYHEGGRF---------CEKGEEWDQ-------------------------ESAVFHLEHAANLGELEAIVGLGLMYSQLPHHILADVSLKETEENKTKGFDYLLKAAEAGDRQSMILVARAFDSGQNLSPDRCQ--------DWLEALHWYNTALEMTDCDEG--------GEYDGMQD-EPRYMMLAREAEMLFTGGYGLEKDPQRSGDLYTQAAEAAMEAMKGRLANQYYQKAEEAWAQME 724
[Close]
BLAST of Elongation factor 2 kinase vs. UniProt/SwissProt
Match: sp|P70531|EF2K_RAT (Eukaryotic elongation factor 2 kinase OS=Rattus norvegicus OX=10116 GN=Eef2k PE=1 SV=1)

HSP 1 Score: 300.442 bits (768), Expect = 2.471e-88
Identity = 152/263 (57.79%), Postives = 197/263 (74.90%), Query Frame = 3 
Query:  384 TISPALKRWFRAVSK--ICKHDDDIDPWHDFTIDTIKPDKAIRYRYSAIKKKWVQDEIWVKLETLPFDHGAMRECFRLKKLSTTGINNNHDWNFSSNYVAKQYINLVNRDVYFEDVKLQMESKLWAEEYNRQNPPKKIDIFQLSIIELIDRENKPLYHIEHFMEGTYLKYNSNSGYVDDSCLRNTPQAFSHFTFERSGHRIIIVDIQGVGDLYTDPQVHTAXXXXXXXXXXXXXXMALFFSSHRCNPICHYLGLSEFDMHQNE 1166
            T SPA    F+   K  I K     DPW +F ++ I  + A R+RY+A+  +W++DE+ +K+ + PF  GAMRECFR KKLS   ++  H W  +SNYVAK+Y+  V+R VYFEDV+LQME+KLW EEYNR  PPK++DI Q+ IIEL DR+ +PL+H+EH++EG Y+KYNSNSG+V D  +R TPQAFSHFTFERSGH++I+VDIQGVGDLYTDPQ+HT  G ++GDGNLG+RGMALFF SH CN IC  +GL+ FD+   E
Sbjct:   71 TGSPASSFHFKEAWKHAIEKAKHMPDPWAEFHLEDIATEHATRHRYNAVTGEWLKDEVLIKMASQPFGRGAMRECFRTKKLSNF-LHAQH-WKGASNYVAKRYLEPVDRSVYFEDVQLQMEAKLWGEEYNRHKPPKQVDIMQMCIIELKDRQGQPLFHLEHYIEGKYIKYNSNSGFVRDDNIRLTPQAFSHFTFERSGHQLIVVDIQGVGDLYTDPQIHTEKGTDFGDGNLGVRGMALFFYSHACNRICQSMGLAPFDLSPRE 331

HSP 2 Score: 122.094 bits (305), Expect = 4.130e-27
Identity = 90/269 (33.46%), Postives = 130/269 (48.33%), Query Frame = 3 
Query: 1752 NLDQEIGHSILAQVHHELARLHESGRFVKSKRLAPGCLHHQFWSNLLNENDSPEESEQKSPTNHDLDINWESCLFHERHAAQLGCLEAVIVMARYCLNMSGHMLQDCPLPPNQNDIECGLDYLWRAADSGDRRSMIELANLYRKTEYFGEIFNEINKTTLEV------NWFEAVKWYKRAFEAVNKLDGQIDSKDAEGRYDSAEDLMPPQEILASMAELYLKGGYGLEKNCQLAGELYSQAAEIATNALQGRQAVKYYELADTAYSQDE 2540
            +L ++IG S+L +VH  + R HE GRF         C   + W                           ES +FH  HAA LG LEA++ +      +  H+L D  L   + +   G DYL +AA++GDR+SMI +A  +               T L +      +W EA+ WY  A E  +  +G        G YD  +D  P   +LA  AE+ L GG+GL+KN Q +G+LY+QAAE A  A++GR A +YYE A+ A++Q E
Sbjct:  512 DLGRKIGKSVLGKVHLAMVRYHEGGRF---------CEKDEEWDQ-------------------------ESAIFHLEHAADLGELEAIVGLGLMYSQLPHHILADVSLEETEENKTKGFDYLLKAAEAGDRQSMILVARAF--------------DTGLNLSPDRCQDWSEALHWYNTALETTDCDEG--------GEYDGIQD-EPQYALLAREAEMLLTGGFGLDKNPQRSGDLYTQAAEAAMEAMKGRLANQYYEKAEEAWAQME 723
[Close]
BLAST of Elongation factor 2 kinase vs. UniProt/SwissProt
Match: sp|O08796|EF2K_MOUSE (Eukaryotic elongation factor 2 kinase OS=Mus musculus OX=10090 GN=Eef2k PE=1 SV=1)

HSP 1 Score: 298.13 bits (762), Expect = 1.407e-87
Identity = 151/263 (57.41%), Postives = 194/263 (73.76%), Query Frame = 3 
Query:  384 TISPALKRWFRAVSK--ICKHDDDIDPWHDFTIDTIKPDKAIRYRYSAIKKKWVQDEIWVKLETLPFDHGAMRECFRLKKLSTTGINNNHDWNFSSNYVAKQYINLVNRDVYFEDVKLQMESKLWAEEYNRQNPPKKIDIFQLSIIELIDRENKPLYHIEHFMEGTYLKYNSNSGYVDDSCLRNTPQAFSHFTFERSGHRIIIVDIQGVGDLYTDPQVHTAXXXXXXXXXXXXXXMALFFSSHRCNPICHYLGLSEFDMHQNE 1166
            T SPA    F+   K  I K     DPW +F ++ I  + A R+RY+A+  +W++DE+ +K+ + PF  GAMRECFR KKLS     +   W  +SNYVAK+YI  V+R VYFEDV+LQME+KLW E+YNR  PPK++DI Q+ IIEL DR  +PL+H+EH++EG Y+KYNSNSG+V D  +R TPQAFSHFTFERSGH++I+VDIQGVGDLYTDPQ+HT  G ++GDGNLG+RGMALFF SH CN IC  +GL+ FD+   E
Sbjct:   71 TGSPASSFHFKEAWKHAIEKAKHMPDPWAEFHLEDIATEHATRHRYNAVTGEWLKDEVLIKMASQPFGRGAMRECFRTKKLSN--FLHAQQWKGASNYVAKRYIEPVDRSVYFEDVQLQMEAKLWGEDYNRHKPPKQVDIMQMCIIELKDRPGQPLFHLEHYIEGKYIKYNSNSGFVRDDNIRLTPQAFSHFTFERSGHQLIVVDIQGVGDLYTDPQIHTEKGTDFGDGNLGVRGMALFFYSHACNRICQSMGLTPFDLSPRE 331

HSP 2 Score: 121.709 bits (304), Expect = 5.276e-27
Identity = 90/269 (33.46%), Postives = 129/269 (47.96%), Query Frame = 3 
Query: 1752 NLDQEIGHSILAQVHHELARLHESGRFVKSKRLAPGCLHHQFWSNLLNENDSPEESEQKSPTNHDLDINWESCLFHERHAAQLGCLEAVIVMARYCLNMSGHMLQDCPLPPNQNDIECGLDYLWRAADSGDRRSMIELANLYRKTEYFGEIFNEINKTTLEV------NWFEAVKWYKRAFEAVNKLDGQIDSKDAEGRYDSAEDLMPPQEILASMAELYLKGGYGLEKNCQLAGELYSQAAEIATNALQGRQAVKYYELADTAYSQDE 2540
            +L ++IG S+L +VH  + R HE GRF         C   + W                           ES +FH  HAA LG LEA++ +      +  H+L D  L   + +   G DYL +AA++GDR SMI +A  +               T L +      +W EA+ WY  A E  +  +G        G YD  +D  P   +LA  AE+ L GG+GL+KN Q +G+LY+QAAE A  A++GR A +YYE A+ A++Q E
Sbjct:  512 DLGRKIGKSVLGKVHLAMVRYHEGGRF---------CEKDEEWDR-------------------------ESAIFHLEHAADLGELEAIVGLGLMYSQLPHHILADVSLKETEENKTKGFDYLLKAAEAGDRHSMILVARAF--------------DTGLNLSPDRCQDWSEALHWYNTALETTDCDEG--------GEYDGIQD-EPQYALLAREAEMLLTGGFGLDKNPQRSGDLYTQAAEAAMEAMKGRLANQYYEKAEEAWAQME 723
[Close]
BLAST of Elongation factor 2 kinase vs. UniProt/SwissProt
Match: sp|O01991|EF2K_CAEEL (Eukaryotic elongation factor 2 kinase OS=Caenorhabditis elegans OX=6239 GN=efk-1 PE=1 SV=1)

HSP 1 Score: 294.664 bits (753), Expect = 7.210e-86
Identity = 152/250 (60.80%), Postives = 190/250 (76.00%), Query Frame = 3 
Query:  450 IDPWHDFTIDTIKPDKAIRYRYSAIKKKWVQDEIWVKLETLPFDHGAMRECFRLKKLSTTGINNNHDWNFSSNYVAKQYINLVNRDVYFEDVKLQMESKLWAEEYNRQNPPKKIDIFQLSIIELIDRENKPLYHIEHFMEGTYLKYNSNSGYVDDSCLRNTPQAFSHFTFERSGHRIIIVDIQGVGDLYTDPQVHTAXXXXXXXXXXXXXXMALFFSSHRCNPICHYLGLSEFDMHQNELVDNDLDQEIA 1199
            IDPW +F I      +A RYRYSAI+K+W +D + V+L    F  GAMREC+RLKK S  G   + DW  SSNYVAK+YI  V+R V F+DV+LQM++KLWAEEYNR NPPKKIDI Q+ +IE+ID +  PLYH+EHF+EG Y+KYNSNSG+V ++  R TPQAFSHFTFERSGH++++VDIQGVGDLYTDPQ+HT  G +YGDGNLG RGMALFF SHRCN IC  + LS F++   E+   ++  E+A
Sbjct:   82 IDPWDEFNIHEYPVQRAKRYRYSAIRKQWTEDIVDVRLHPDSFARGAMRECYRLKKCSKHG--TSQDW--SSNYVAKRYICQVDRRVLFDDVRLQMDAKLWAEEYNRYNPPKKIDIVQMCVIEMIDVKGSPLYHLEHFIEGKYIKYNSNSGFVSNAA-RLTPQAFSHFTFERSGHQMMVVDIQGVGDLYTDPQIHTVVGTDYGDGNLGTRGMALFFHSHRCNDICETMDLSNFELSPPEIEATEVAMEVA 326

HSP 2 Score: 86.6557 bits (213), Expect = 4.632e-16
Identity = 88/297 (29.63%), Postives = 147/297 (49.49%), Query Frame = 3 
Query: 1707 SMKENQKPSSATHPTNLDQEIGH--SILAQVHHELARLHESGRFVK----SKRLAPGCLHHQFWSNLLNENDSPEESEQKSPTNHDLDINWESCLFHERHAAQLGCLEAVIVMARYCLNMSGHMLQDCP---LPPN-----QNDI------------ECGLDYLWRAADSGDRRSMIELANLYRKTEYFGEIFNEINKTTLEVNWFEAVKWYKRAFEAVNKLDGQIDSKDAEGRYDSAEDLMPPQEILASMAELYLKGGYGLEKNCQLAGELYSQAAEIATNALQGRQAVKYYELAD 2519
            S++  Q  ++  +  ++ Q  GH  S+L Q+H +L+R HE GRFV+     K +  G           +END+      + P  +D     +S +FH   A + G LEAV+  A   L +   +L++     L PN     +N I            E G D +  AA+ GD+ +M+ +A+ Y   ++ G      N+ T   ++ +++ WY+R      + + ++DS   +  + S   L    EILA MAE+Y +GGYGL ++ + A  L+++AAE A  A+ G+ A KYYE A+
Sbjct:  500 SLQLQQMAANLENDEDVPQVTGHQFSVLGQIHIDLSRYHELGRFVEVDSEHKEMLEG-----------SENDA------RVPIKYDK----QSAIFHLDIARKCGILEAVLTSAHIVLGLPHELLKEVTVDDLFPNGFGEQENGIRADKGQKPCDLEEFGSDLMEIAAEMGDKGAMLYMAHAYETGQHLGP-----NRRT---DYKKSIDWYQRVVGF--QEEEELDSDCGKTTFSSFAPLTR-HEILAKMAEMYKEGGYGLNQDFERAYGLFNEAAEAAMEAMNGKLANKYYEKAE 764
[Close]
BLAST of Elongation factor 2 kinase vs. UniProt/SwissProt
Match: sp|Q54DK4|AK1_DICDI (Alpha-protein kinase 1 OS=Dictyostelium discoideum OX=44689 GN=ak1 PE=3 SV=1)

HSP 1 Score: 206.453 bits (524), Expect = 2.512e-53
Identity = 113/221 (51.13%), Postives = 153/221 (69.23%), Query Frame = 3 
Query:  492 DKAIRYRYSAIKKKWVQDEIWVKLETLPFDHGAMRECFRLKKLSTTGINNNHDWNFSSNYVAKQYINL-VNRDVYFEDVKLQMESKLWAEEYNRQNPPKKIDIFQLSIIELIDRENKPLYHIEHFMEGTYLKYNSNSGYVDDSCLRNTPQAFSHFTFERSGHRIIIVDIQGVGDLYTDPQVHTAXXXXXXXXXXXXXXMALFFSSHRCNPICHYLGLSEFD 1151
            ++ IR+R+ A   KWVQ    V  E  PF  GAMR+ FR+K LS  G         SS  VAK + +   +R VYF+DV++Q  SK  AE +N ++PPKKID     ++EL++R+ KP   +E+F+EG Y K+N+N GY +D   RNTPQAFSHF++E SG ++I+VDIQGVGD+YTDPQ+H+ADG  +G GNLG+ G+  FFS+H+CNPICHYLGLS  +
Sbjct:  984 ERVIRHRFDAKLGKWVQTATIVITEPTPFAEGAMRKAFRMKDLSAEGP--------SSQMVAKLFKDSNEDRMVYFKDVEMQTYSKEIAERFNLKSPPKKIDFVPAFVMELVERQGKPFCAVEYFIEGKYEKHNNNFGYKNDYD-RNTPQAFSHFSYEDSGCQLIVVDIQGVGDVYTDPQIHSADGQGFGKGNLGIEGIKRFFSTHQCNPICHYLGLSSVN 1195
[Close]
BLAST of Elongation factor 2 kinase vs. TrEMBL
Match: A0A0R3ST81 (Alpha-type protein kinase domain-containing protein OS=Hymenolepis diminuta OX=6216 GN=HDID_LOCUS8579 PE=4 SV=1)

HSP 1 Score: 508.449 bits (1308), Expect = 1.327e-163
Identity = 345/819 (42.12%), Postives = 449/819 (54.82%), Query Frame = 3 
Query:  390 SPALKRWFRAVSKICKHDDDIDPWHDFTIDTIKPDKAIRYRYSAIKKKWVQDEIWVKLETLPFDHGAMRECFRLKKLSTTGINNNHDWNFSSNYVAKQYINLVNRDVYFEDVKLQMESKLWAEEYNRQNPPKKIDIFQLSIIELIDRENKP----------------------------LYHIEHFMEGTYLKYNSNSGYVDDSCLRNTPQAFSHFTFERSGHRIIIVDIQGVGDLYTDPQVHTAXXXXXXXXXXXXXXMALFFSSHRCNPICHYLGLSEFDMHQNE---LVDNDL--------DQEIADHDISTISIDALPE----EDSCAFS---SKSYNEIKKRNRSISFKMSGTVIRDGRT-SPCVTSPA--------FLDQLFPAPIDLIRAMSVDSGVQSVST----PFVSQGNFMTXXXXXXXXXXXXXXXXXXXXHSGLGAYHHPYEIKTNLSQIINSRKL--FRRRQRNYSDGSDIDASLVSYEEHLAVYYSMKENQKPSSATHPTNLDQEIGHSILAQVHHELARLHESGRFVKSKRLAPGCLHHQFWSNLLNENDSPEESEQKSPTNHDLDINWESCLFHERHAAQLGCLEAVIVMARYCLNMSGHMLQDCPLPPNQNDIECGLDYLWRAADSGDRRSMIELANLYRKTEYFG-------------EIFNEINKTTLEVN----------------------WFEAVKWYKRAFEAV-----NKLDGQIDSK-DAEGRYDSAEDLMPPQEILASMAELYLKGGYGLEKNCQLAGELYSQAAEIATNALQGRQAVKYYELADTAYSQDE 2540
            SP  K W  AV K+ K  D +DPW DF + +     A+R+RYSA+KKKW++D I VK+E  PF+ GAMRECFRLKK       +N DW+ +SNYVAK+YI+ VN  VY +DV+LQME+KLWAE +N+Q+PPKK+D+FQ+S+IE++   N P                             YHIE +M+G Y KYNSNSGYVDD   RNTPQAFSHFTFE SGHR+++VDIQGVGDLYTDPQ+HT+DGL Y DGNLGLRGMALFF SHRCNP+C  L L  FD+ +NE   L D ++        D E    +I   S D LP+    + S A S   S +   ++ R RS+S+ M         + S C  S A          ++ F       R  S  +G  + S+      VS    ++SS    D         +N   SG       ++ +T+    + SR L    RR R  S+ SD+D  + S   H  ++    E  KPSSA HP+NLDQEIG SIL Q+HH LA +HE+GRF    R A G         L    D  +E+ +   T+    I+WES LFHER AAQLGCLEA+ +MA Y L +   +L DCP+ P    +  G++YLWR +  GDRR MI LA     +  FG              I   +N  +  V+                      W EA+KWY++A E           G  D   DAEGRYDSAEDL P   +LA MAE+Y  GG+GL+ +  +AG+LY++AAE AT    GR A KYYELA+ AY++ E
Sbjct:   39 SPGAKLWHNAVRKVLKEADKLDPWRDFDLKSTPTLAAVRHRYSALKKKWIKDNILVKVEDKPFNRGAMRECFRLKKAP-----DNGDWSAASNYVAKRYISPVNSSVYMDDVRLQMEAKLWAEAFNKQDPPKKVDVFQMSVIEIL--PNAPDSPSDSKRRGSITLINNPSPKSKNSSSLFYHIERYMDGEYRKYNSNSGYVDDKP-RNTPQAFSHFTFEHSGHRLLVVDIQGVGDLYTDPQIHTSDGLGYNDGNLGLRGMALFFHSHRCNPLCEVLQLKPFDLSENEVKALYDGEVIDEENRFDDDEENSEEIFEAS-DGLPQLKANDHSLASSLTDSDNAMPLQHRKRSLSYGMIPLAFSQCPSLSTCYRSSAKHLYGPTVSKEEEFRLVPRRFRTYSATAGCSTTSSAGSKALVSPNRRLSSSTEGVDTDSPCPPDTANDWDSGFS-----FDDETSGFSAVPSRPLQPRVRRPRTISESSDVDNEVGSSLFHQNIH----ETHKPSSAAHPSNLDQEIGQSILGQLHHVLASMHEAGRF---SRKANGGWSTNGLGGL--SIDGFDENHEHHDTDSASSIDWESVLFHERIAAQLGCLEALTIMANYYLGLPTSILSDCPIRPTDEHLNMGVEYLWRCSIGGDRRCMILLARYMDASVIFGGTGSDNPPVFDRATIRGALNLRSTPVDDFLVLLSSHRGFPLPKDYANHPWDEAIKWYRKAIENAGIAVPGGGSGDADEGCDAEGRYDSAEDLSPVHRLLARMAEMYEVGGHGLKADLNIAGDLYNEAAEAATKEANGRLAEKYYELAEEAYAKGE 834
[Close]
BLAST of Elongation factor 2 kinase vs. TrEMBL
Match: A0A293M251 (Alpha-type protein kinase domain-containing protein (Fragment) OS=Ornithodoros erraticus OX=265619 PE=4 SV=1)

HSP 1 Score: 421.779 bits (1083), Expect = 1.401e-131
Identity = 287/731 (39.26%), Postives = 399/731 (54.58%), Query Frame = 3 
Query:  405 RWFRAVSKICKHDDDIDPWHDFTIDTIKPDKAIRYRYSAIKKKWVQDEIWVKLETLPFDHGAMRECFRLKKLSTTGINNNHDWNFSSNYVAKQYINLVNRDVYFEDVKLQMESKLWAEEYNRQNPPKKIDIFQLSIIELIDRENKPLYHIEHFMEGTYLKYNSNSGYVDDSCLRNTPQAFSHFTFERSGHRIIIVDIQGVGDLYTDPQVHTAXXXXXXXXXXXXXXMALFFSSHRCNPICHYLGLSEFDMHQNELVDNDLDQEIADHDISTISIDALPEEDSCAFSSKSYNEIKKRNRSISFKMSGTVIRDGRTSPCVTSPAFLDQLFPAPIDLIRAMS-------VDSGVQSVSTPFVSQGNFMTXXXXXXXXXXXXXXXXXXXXHSGLGAYHHPYEIKTNLSQIINSRKLFRRRQRNYSDGSDIDASLVSYEEHLAVYYSMKENQKPSSATHPTNLDQ---EIGH------SILAQVHHELARLHESGRFVKSKRLAPGCLHHQFWSNLLNENDSPEESEQKSPTNHDLDI---NWESCLFHERHAAQLGCLEAVIVMARYCLNMSGHMLQDCPLPPNQNDIECGLDYLWRAADSGDRRSMIELANLYRKTEYFGEIFNEINKTTLEVNWFEAVKWYKRAFEAVNKLDGQIDSKDAEGRYDSAEDLMPPQEILASMAELYLKGGYGLEKNCQLAGELYSQAAEIATNALQGRQAVKYYELADTAYSQDE 2540
            RW RA  +    +D   PW  F ++ +KP++ +RYRY+A+ K  ++DE  VK++  PF  GAMRECFR+KKLS     +N  W  ++NYVAK+Y+  V R+VYFEDVKLQM++KLW EE+NR NPPKK+DIFQ+S+IE ++R  +PLYH+EHF+EG Y KYNSNSG++    +R TPQAFSHFTFERSGH +++VDIQGVGDLYTDPQ+HTA G  YGDGNLGLRGMALFF SH CN +C  LGL+ FD+   EL        +      T       +E+ C     S +E +K++                    +  P    + +  P D+ +A +        DSG +S+S+     G+  T+     +  L+S    +   +S    Y    E+ + L Q  NS +   RR R  S+GS   ++L    E    +  +    +PSS T+   + Q   E G       S+L Q+H E+ + HE+GRF                                SP  H +D    +  S +FH   AAQ G LEAV+ +A+  L +   +LQD  LP ++++   G+DYL +AA SGDR SMI +A  +      G        T+ + +W +AV WY  A    +  +G        G YD   D  P   +LA  AELYL+GG+GL ++C  AGELY  AAE AT A++GR A KYY L++ A+SQ E
Sbjct:   87 RWKRAAWQALHMED---PWAQFHLEKLKPERVVRYRYNALTKSLLKDEALVKMDKAPFGRGAMRECFRMKKLSHFAHTSN--WATAANYVAKRYLEPVEREVYFEDVKLQMDAKLWGEEFNRHNPPKKVDIFQVSVIEFVNRPGRPLYHLEHFIEGKYTKYNSNSGFISSENMRLTPQAFSHFTFERSGHELVVVDIQGVGDLYTDPQIHTARGTEYGDGNLGLRGMALFFHSHVCNSVCRSLGLTPFDLSPAELKAASCCAAVPPQGSKTC---VRGKEELCL----SMSEYEKQH----------------LEEVLGQPRLRQRTYSNPSDMHKAQNGAPVLRHQDSGFRSLSS-----GSEDTNDDDPLEFDLASDSEDAESANSAPATYVSSGEVASLLLQRQNSGR--PRRTRYESEGS---STLGDEHERAEFHKLVAMKARPSSVTNEVLIRQLLREQGQHRMPQRSLLGQIHLEMTKCHENGRF--------------------------------SPEGHIIDAGNYDQRSAMFHLEKAAQCGSLEAVLTLAKLHLGLHHDLLQDVVLPESEDNTNKGMDYLIQAAYSGDRASMISVAKAFDTGTNLG--------TSRKRSWKDAVYWYDLAVTTTDDDEG--------GEYDGCMD-DPSYLLLARQAELYLEGGFGLNRDCNKAGELYQTAAEEATAAMKGRLANKYYMLSEEAFSQIE 730
[Close]
BLAST of Elongation factor 2 kinase vs. TrEMBL
Match: K1RAD5 (Eukaryotic elongation factor 2 kinase OS=Crassostrea gigas OX=29159 GN=CGI_10025610 PE=3 SV=1)

HSP 1 Score: 417.542 bits (1072), Expect = 1.881e-130
Identity = 277/714 (38.80%), Postives = 388/714 (54.34%), Query Frame = 3 
Query:  390 SPALKRWFRAVSKICKHDDDIDPWHDFTIDTIKPDKAIRYRYSAIKKKWVQDEIWVKLETLPFDHGAMRECFRLKKLSTTGINNNHDWNFSSNYVAKQYINLVNRDVYFEDVKLQMESKLWAEEYNRQNPPKKIDIFQLSIIELIDRENKPLYHIEHFMEGTYLKYNSNSGYVDDSCLRNTPQAFSHFTFERSGHRIIIVDIQGVGDLYTDPQVHTAXXXXXXXXXXXXXXMALFFSSHRCNPICHYLGLSEFDMHQNELVDNDLDQEIADHDISTISIDALPEEDSCAFSSKSYNEIKKRNRSISFKMSGTVIRDGRTSPCVTSPAFLDQLFPAPIDLIRAMSVDSGVQSVSTPFVSQGNFMTXXXXXXXXXXXXXXXXXXXXHSGLGAYHHPYEIKTNLSQIINSRKLFRRRQRNYSDGSDIDASLVSYEEHLAV-YYSMKENQKPSSATHPTN----LDQEIGHSILAQVHHELARLHESGRFVKSKRLAPGCLHHQFWSNLLNENDSPEESEQKSPTNHDLDINWESCLFHERHAAQLGCLEAVIVMARYCLNMSGHMLQDCPLPPNQNDIECGLDYLWRAADSGDRRSMIELANLYRKTEYFGEIFNEINKTTLEVNWFEAVKWYKRAFEAVNKLDGQIDSKDAEGRYDSAEDLMPPQEILASMAELYLKGGYGLEKNCQLAGELYSQAAEIATNALQGRQAVKYYELA 2516
            S A   W  A+ K     D  DPW  F I+ IK +  IR+RY+  KK W +DE+ VK+   PF+ GAMR+CFRLKK+ST   + + DW+ + NYVAK+YI  V+RDVYF+DV+LQM++K+W EEYNR NPPKK+DIFQ+ I+E  DR  +PLYH+EHF+EG Y+KYNSNSG+VD++ LR TPQAFSHFTFERS H +I+VDIQGVGDLYTDPQ+HT     YGDGNLG +GMALFF SH CN IC+ L L+EFD+   E+  +     +     S +      E + C   S S  +I         +   T + DG T   + SP+  D+           MSVDS      +P                              SG+     PY +                R R+ SD +D  +S+   EE  A    +  +N +PS      +    ++ +IG SIL +VHHE+A+ HE GRFV                      DS +E            I+WES +FHE HAA+LG LEA++ MA+  L     +L +C + P+      G+D++  AA++GDR +M+ +   +   +  G        T   V+W +AV WY++A +  +  +G        G++D   +  P   ++A  AE+Y +GG+GL+K+ Q AG+LY++AAE A  A++GR A KY+ LA
Sbjct:   84 SRAQNHWIMAIKKA---RDLSDPWASFHIEDIKTEFCIRHRYNPHKKTWTKDEVQVKMMKKPFNRGAMRQCFRLKKIST--FSRSGDWSHAQNYVAKRYIEKVDRDVYFQDVRLQMDAKVWGEEYNRHNPPKKVDIFQMYILEFKDRPGEPLYHLEHFIEGEYIKYNSNSGFVDEN-LRYTPQAFSHFTFERSAHNLIVVDIQGVGDLYTDPQIHTVGSCEYGDGNLGAKGMALFFHSHICNDICNSLNLTEFDLSPREIATHK--DFLRAQRKSIMQTKVRGEIEQCLSLSPSSEKIDITRFLDHQRTCSTGVSDGHTPTDLDSPSMDDE---------EPMSVDS-----PSP------------------------------SGV-----PYGV----------------RFRSPSD-TDSQSSMTKEEEEEAFNRMAGSQNARPSCVALEKDFRKLMNHKIGDSILGKVHHEMAKYHEVGRFVL--------------------GDSKDEKL----------IDWESAIFHEEHAAELGELEAMVTMAKLYLGQDREVLVNCVVEPSDEHTNRGVDFMVEAAEAGDRGAMVYMGRAFETGDGLG--------TLRSVSWEDAVYWYEQAVKTHDNDEG--------GQFDCTIN-DPSYTLMAKQAEMYRQGGHGLDKDPQRAGDLYNEAAEAAMEAMKGRLANKYFALA 676
[Close]
BLAST of Elongation factor 2 kinase vs. TrEMBL
Match: A0A2R5LEC7 (Putative elongation factor 2 kinase ixodes scapularis elongation factor 2 kinase (Fragment) OS=Ornithodoros turicata OX=34597 PE=4 SV=1)

HSP 1 Score: 414.461 bits (1064), Expect = 7.877e-129
Identity = 293/769 (38.10%), Postives = 408/769 (53.06%), Query Frame = 3 
Query:  327 RRPHSLSISWNSPDSDRTDTISPA------LKRWFRAVSKICKHDDDIDPWHDFTIDTIKPDKAIRYRYSAIKKKWVQDEIWVKLETLPFDHGAMRECFRLKKLSTTGINNNHDWNFSSNYVAKQYINLVNRDVYFEDVKLQMESKLWAEEYNRQNPPKKIDIFQLSIIELIDRENKPLYHIEHFMEGTYLKYNSNSGYVDDSCLRNTPQAFSHFTFERSGHRIIIVDIQGVGDLYTDPQVHTAXXXXXXXXXXXXXXMALFFSSHRCNPICHYLGLSEFDMHQNELVDNDLDQEIADHDISTISIDALPEEDS--CAFSSK----SYNEIKKRNRSISFKMSGTVIRDGRTSPCVTSPAFLDQLFPAPIDLIRAMS-------VDSGVQSVSTPFVSQGNFMTXXXXXXXXXXXXXXXXXXXXHSGLGAYHHPYEIKTNLSQIINSRKLFRRRQRNYSDGSDIDASLVSYEEHLAVYYSMKENQKPSSATHPTNLDQ---EIGH------SILAQVHHELARLHESGRFVKSKRLAPGCLHHQFWSNLLNENDSPEESEQKSPTNHDLDI-NWE--SCLFHERHAAQLGCLEAVIVMARYCLNMSGHMLQDCPLPPNQNDIECGLDYLWRAADSGDRRSMIELANLYRKTEYFGEIFNEINKTTLEVNWFEAVKWYKRAFEAVNKLDGQIDSKDAEGRYDSAEDLMPPQEILASMAELYLKGGYGLEKNCQLAGELYSQAAEIATNALQGRQAVKYYELADTAYSQDE 2540
            +R   + +   SP     + + P       + RW RA  +    +D   PW  F ++ +KP++ +RYRY+A+ K  ++D+  VK++  PF  GAMRECFR+KKLS      N  W  ++NYVAK+Y+  V R+VYFEDVKLQM++KLW EE+NR NPPKK+DIFQ+S+IE ++R  +PLYH+EHF+EG Y KYNSNSG++    +R TPQAFSHFTFERSGH +++VDIQGVGDLYTDPQ+HT  G  YGDGNLGLRGMALFF SH CN +C  LGL+ FD+   E       Q+ A       S  A+P + S  C    +    S +E +K++                    +  P    + +  P D+ +  +        DSG +S+S+     G+  T+     +  L+S    + G  S    Y    E+ + L Q  NS +   RR R  S+ S   ++L +  E       +    +PSS T+   + Q   E G       S+L Q+H E+ + HE+GRF                                SP  H +D  N++  S +FH   AAQ G LEAV+ +A+  L +   +LQD  LP +++    G+DYL +AA SGDR SMI +A  +      G        T  + +W +AV WY  A    +  +G        G YD   D  P   +LA  AELY +GGYGL K+C  AGELY  AAE AT A++GR A KYY L++ A+SQ E
Sbjct:   49 KRKSVVEMVTRSPRKKAVELVRPLSPSEVRILRWKRAAWQALHMED---PWAQFHLEKLKPERVVRYRYNALTKSLLKDDALVKMDKAPFGRGAMRECFRMKKLSNFAHTCN--WATAANYVAKRYLEPVEREVYFEDVKLQMDAKLWGEEFNRHNPPKKVDIFQVSVIEFVNRPGRPLYHLEHFIEGKYTKYNSNSGFISSENMRLTPQAFSHFTFERSGHELVVVDIQGVGDLYTDPQIHTVRGTEYGDGNLGLRGMALFFHSHICNSVCRSLGLTPFDLSPAE-------QKAA-------SCGAIPPQGSKTCVRGKEELCLSMSEYEKQH----------------LEEVLGQPRLRQRAYSNPTDVNQPQNGVPILRHQDSGFRSLSS-----GSEDTNDDDPLEFDLASDSEDAEGASSAPATYVTSGEVASLLLQRQNSGR--PRRTRYESESS---STLGNEHERAEFQKLVAMKARPSSVTNEVLIRQLLREQGQHRMPQRSLLGQIHLEMTKCHENGRF--------------------------------SPEGHVIDAGNYDQVSAMFHLEKAAQCGSLEAVLTLAKIHLGLPHDLLQDVVLPESEDSTNKGMDYLVQAAYSGDRASMISVAKAFDSGANLG--------TNRKRSWKDAVYWYDLAVTTTDDDEG--------GEYDGCMD-DPSYLLLARQAELYQEGGYGLNKDCNKAGELYQTAAEEATAAMKGRLANKYYMLSEEAFSQIE 723
[Close]
BLAST of Elongation factor 2 kinase vs. TrEMBL
Match: A0A131XNL1 (Putative elongation factor 2 kinase (Fragment) OS=Hyalomma excavatum OX=257692 PE=2 SV=1)

HSP 1 Score: 410.223 bits (1053), Expect = 2.898e-128
Identity = 281/726 (38.71%), Postives = 396/726 (54.55%), Query Frame = 3 
Query:  396 ALKRWFRAVSKICKHDDDIDPWHDFTIDTIKPDKAIRYRYSAIKKKWVQDEIWVKLETLPFDHGAMRECFRLKKLSTTGINNNHDWNFSSNYVAKQYINLVNRDVYFEDVKLQMESKLWAEEYNRQNPPKKIDIFQLSIIELIDRENKPLYHIEHFMEGTYLKYNSNSGYVDDSCLRNTPQAFSHFTFERSGHRIIIVDIQGVGDLYTDPQVHTAXXXXXXXXXXXXXXMALFFSSHRCNPICHYLGLSEFDMHQNELVDNDLDQEIADHDISTISIDALPEEDSCAFSSKSYNEIKKRNRSISFKMSGTVIRDGRTSPCVTSPAFL---DQLFPAPIDLIRAMSVDSGVQSVSTPFVSQGNFMTXXXXXXXXXXXXXXXXXXXXHSGLGAYHHPYEIKTNLSQIINSRKLFRRRQRNYSDGSDIDASLVSYEEHLAVYYS--MKENQKPSSATHPTNL----DQEIG-------HSILAQVHHELARLHESGRFVKSKRLAPGCLHHQFWSNLLNENDSPEESEQKSPTNHDLDINWESCLFHERHAAQLGCLEAVIVMARYCLNMSGHMLQDCPLPPNQNDIECGLDYLWRAADSGDRRSMIELANLYRKTEYFGEIFNEINKTTLEVNWFEAVKWYKRAFEAVNKLDGQIDSKDAEGRYDSAEDLMPPQEILASMAELYLKGGYGLEKNCQLAGELYSQAAEIATNALQGRQAVKYYELADTA 2525
            A  +W RA  +    +D   PW  F ++  K ++  RYRY+A+ K W++DE  VK+   PF  GAMRECFR+KKLS+     N  W  +SNYVAK+Y+  V+R  YF+DV+LQM++KLWAEE+NR NPPKK+DIFQ+SIIE ++R   PLYH+EHF+EG+Y+KYNSNSG++     R TPQAFSHFTFERSGH +++VDIQGVGDLYTDPQ+HTA G  YGDGNLG+RGMALFF SH CN +C  LGL+ FD+  +E++       IA    + +       E+ C       +E ++++ + +       IR   +SPC +S       +  FP           DSG +S+S+     G+  T      D  L S    +  L S +   H    +  + +  + +R   RRRQR  S+ S I       +EH    +   + +  +PSS      L     Q+ G        S+L Q+H E+A+ HE+GRF                     +   PE    ++           + +FH   AA+ G LEA++V+A+  L +   +L+D  LP ++ +   G++YL +AA +GDR SMI LA      E  G        T  + NW +AV WY  A    +  +G        G YD   D  PP  +LA  AELYL+GGY LE++  +AGELY +AA  AT A++GR A KY++LA+ A
Sbjct:    1 AALKWKRAARQALHMED---PWAMFHLERFKAERVRRYRYNALNKAWLEDEALVKMAPDPFGRGAMRECFRMKKLSSFAPAQN--WAHASNYVAKRYLEPVDRSTYFDDVRLQMDAKLWAEEFNRHNPPKKVDIFQVSIIEFVERPGSPLYHMEHFIEGSYIKYNSNSGFISSQATRLTPQAFSHFTFERSGHELLVVDIQGVGDLYTDPQIHTAHGSEYGDGNLGVRGMALFFRSHTCNCVCTGLGLAPFDLAPSEMLVGTPASAIAQGAKTRLR----GHEELCV----GMSEYERQHLAEALGPPRQRIRT-YSSPCDSSRDVGHRENDFFPM------LQQQDSGFRSLSS-----GSEDTLEDYSHDLDLGSDSEDTETLQSQITNGHQ--HMNGDRASAVPAR--LRRRQRYDSESSTIG------DEHERAEFQRLVAQRARPSSVMDEVKLRLLVRQQQGRPLDESQRSVLGQIHLEMAKCHENGRF--------------------GDTTHPEGKYDQA-----------AAVFHLEQAARCGVLEALLVLAKVHLGLPHDLLEDWTLPESEENTSKGVEYLEQAARAGDRGSMIALAKALDTGEGLG--------TQKQRNWQDAVLWYNMAVTTTDNDEG--------GEYDGCMD-DPPYLLLARQAELYLQGGYSLERDPAMAGELYQEAAAAATAAMKGRLANKYFQLAEEA 643
[Close]
BLAST of Elongation factor 2 kinase vs. Ensembl Cavefish
Match: eef2k (eukaryotic elongation factor 2 kinase [Source:NCBI gene;Acc:103031207])

HSP 1 Score: 371.318 bits (952), Expect = 9.579e-116
Identity = 268/755 (35.50%), Postives = 403/755 (53.38%), Query Frame = 3 
Query:  303 NSIKYRNQ-RRPHSLSISWNSPDSDRTDTISPALKRWFRAVSKICKHDDDIDPWHDFTIDTIKPDKAIRYRYSAIKKKWVQDEIWVKLETLPFDHGAMRECFRLKKLSTTGINNNHDWNFSSNYVAKQYINLVNRDVYFEDVKLQMESKLWAEEYNRQNPPKKIDIFQLSIIELIDRENKPLYHIEHFMEGTYLKYNSNSGYVDDSCLRNTPQAFSHFTFERSGHRIIIVDIQGVGDLYTDPQVHTAXXXXXXXXXXXXXXMALFFSSHRCNPICHYLGLSEFDMHQNELVDNDLDQEIADHDISTISIDALPEEDSCAFSSKSYNEIKKRNRSISFK-MSGTVIRDGRTSPCVTSPAFLDQLFPAPIDLIRAMSVDSGVQSVSTPFVSQGNFMTXXXXXXXXXXXXXXXXXXXXHSGLGAYHHPYEIKTNLSQIINSRKLFRRRQRNYSDGSDIDASLVSYEEHLAVYYSMKEN-QKPSSATHPTN------LDQEIGHSILAQVHHELARLHESGRFVKSKRLAPGCLHHQFWSNLLNENDSPEESEQKSPTNHDLDINWESCLFHERHAAQLGCLEAVIVMARYCLNMSGHMLQDCPLPPNQNDIECGLDYLWRAADSGDRRSMIELANLYRKTEYFGEIFNEINKTTLEVNWFEAVKWYKRAFEAVNKLDGQIDSKDAEGRYDSAEDLMPPQEILASMAELYLKGGYGLEKNCQLAGELYSQAAEIATNALQGRQAVKYYELADTAYSQDE 2540
            NS  Y+N+ + P   S+ + S       T   A+++  RA+          DPW +F ++ ++ +  IRYRY+AI   WVQD++++K+ + PF  GAMREC+R KKLS    +++ +W  +SNYVAK+Y+  V+RDVYFEDV+LQME+KLW EEYNR  PPK++DI Q+ ++E+  R  KPLYH+EH++EG Y+KYNSNSG+V D  +R TPQAFSHFTFERSGH++I+VDIQGVGDLYTDPQ+HT  G ++GDGNLG+RGMALFF SH CN IC  +GL+ FD+   E    D   ++    + +        E+ C            R R+ SF  +S  + R   TS    + +  + +  +P+ L   +SVD      S  F+++ N                 +      SG G   +P E ++      +  +      R+YS+ SD D+     EE  + ++S + +  +PS             L+++IG S+L +VH  + R HE+GRF                     E D+P +               +S L+H   AA  G LEA++ + +  L +  H+L +  L  +  + + G  +L +AA++GDR SM+ +A        F    N  +  T   +W EAV+WY       +  +G        G +D  +D  P   +LA  AEL+  GG+ L  + Q AG+L+++AAE A  A++GR A +YY  A+ A+S  E
Sbjct:   76 NSFTYKNKNKEPEVRSVRFGSLTEKGRATWKHAIEK-ARAMP---------DPWAEFHLEEVETEPCIRYRYNAITGDWVQDQVFIKMSSQPFGKGAMRECYRTKKLSN--FSHSSNWKCASNYVAKRYMETVDRDVYFEDVRLQMEAKLWGEEYNRHRPPKQVDIMQMCVVEMASRPGKPLYHLEHYIEGQYIKYNSNSGFVRDDNIRLTPQAFSHFTFERSGHQLIVVDIQGVGDLYTDPQIHTEKGTDFGDGNLGVRGMALFFHSHLCNKICKSMGLTPFDVAPAESTQLDCTNKL----LQSAKTMLRGCEEQCG---------SPRVRTTSFTHVSPHLSRLSETSSADENLSDAESVPCSPLSL--GVSVDRSPLGWS--FMNEMN-----------EGDRNNTDHKASDSG-GDSGYPSERRSEGDLAEHHDRARPAYNRHYSE-SDEDSVRRLTEEKWSFFHSSRAHIHRPSCVAVEVERLNNLMLERKIGKSVLGKVHLAMVRYHEAGRFC--------------------EKDAPWDQ--------------KSALYHLERAAMCGELEAIVALGQCYLQLPHHILSELELEDSDENRKKGFRFLLQAAEAGDRPSMMLVARA------FDTGINLPSDRT--QDWEEAVQWYDCVLNMTDYDEG--------GEFDGMQD-DPRYLLLAREAELFQMGGFNLTADPQRAGDLFTEAAEAAMEAMKGRLANQYYMKAEEAWSAME 737
[Close]
BLAST of Elongation factor 2 kinase vs. Ensembl Cavefish
Match: eef2k (eukaryotic elongation factor 2 kinase [Source:NCBI gene;Acc:103031207])

HSP 1 Score: 305.834 bits (782), Expect = 2.066e-91
Identity = 154/289 (53.29%), Postives = 209/289 (72.32%), Query Frame = 3 
Query:  303 NSIKYRNQ-RRPHSLSISWNSPDSDRTDTISPALKRWFRAVSKICKHDDDIDPWHDFTIDTIKPDKAIRYRYSAIKKKWVQDEIWVKLETLPFDHGAMRECFRLKKLSTTGINNNHDWNFSSNYVAKQYINLVNRDVYFEDVKLQMESKLWAEEYNRQNPPKKIDIFQLSIIELIDRENKPLYHIEHFMEGTYLKYNSNSGYVDDSCLRNTPQAFSHFTFERSGHRIIIVDIQGVGDLYTDPQVHTAXXXXXXXXXXXXXXMALFFSSHRCNPICHYLGLSEFDMHQNE 1166
            NS  Y+N+ + P   S+ + S       T   A+++  RA+          DPW +F ++ ++ +  IRYRY+AI   WVQD++++K+ + PF  GAMREC+R KKLS    +++ +W  +SNYVAK+Y+  V+RDVYFEDV+LQME+KLW EEYNR  PPK++DI Q+ ++E+  R  KPLYH+EH++EG Y+KYNSNSG+V D  +R TPQAFSHFTFERSGH++I+VDIQGVGDLYTDPQ+HT  G ++GDGNLG+RGMALFF SH CN IC  +GL+ FD+   E
Sbjct:   76 NSFTYKNKNKEPEVRSVRFGSLTEKGRATWKHAIEK-ARAMP---------DPWAEFHLEEVETEPCIRYRYNAITGDWVQDQVFIKMSSQPFGKGAMRECYRTKKLSN--FSHSSNWKCASNYVAKRYMETVDRDVYFEDVRLQMEAKLWGEEYNRHRPPKQVDIMQMCVVEMASRPGKPLYHLEHYIEGQYIKYNSNSGFVRDDNIRLTPQAFSHFTFERSGHQLIVVDIQGVGDLYTDPQIHTEKGTDFGDGNLGVRGMALFFHSHLCNKICKSMGLTPFDVAPAE 352

HSP 2 Score: 93.5893 bits (231), Expect = 3.743e-19
Identity = 79/262 (30.15%), Postives = 126/262 (48.09%), Query Frame = 3 
Query: 1755 LDQEIGHSILAQVHHELARLHESGRFVKSKRLAPGCLHHQFWSNLLNENDSPEESEQKSPTNHDLDINWESCLFHERHAAQLGCLEAVIVMARYCLNMSGHMLQDCPLPPNQNDIECGLDYLWRAADSGDRRSMIELANLYRKTEYFGEIFNEINKTTLEVNWFEAVKWYKRAFEAVNKLDGQIDSKDAEGRYDSAEDLMPPQEILASMAELYLKGGYGLEKNCQLAGELYSQAAEIATNALQGRQAVKYYELADTAYSQDE 2540
            L+++IG S+L +VH  + R HE+GRF                     E D+P +               +S L+H   AA  G LEA++ + +  L +  H+L +  L  +  + + G  +L +AA++GDR SM+ +A        F    N  +  T   +W EAV+WY       +  +G        G +D  +D  P   +LA  AEL+  GG+ L  + Q AG+L+++AAE A  A++GR A +YY  A+ A+S  E
Sbjct:  508 LERKIGKSVLGKVHLAMVRYHEAGRFC--------------------EKDAPWDQ--------------KSALYHLERAAMCGELEAIVALGQCYLQLPHHILSELELEDSDENRKKGFRFLLQAAEAGDRPSMMLVARA------FDTGINLPSDRT--QDWEEAVQWYDCVLNMTDYDEG--------GEFDGMQD-DPRYLLLAREAELFQMGGFNLTADPQRAGDLFTEAAEAAMEAMKGRLANQYYMKAEEAWSAME 718
[Close]
BLAST of Elongation factor 2 kinase vs. Ensembl Cavefish
Match: eef2k (eukaryotic elongation factor 2 kinase [Source:NCBI gene;Acc:103031207])

HSP 1 Score: 306.22 bits (783), Expect = 4.438e-91
Identity = 154/289 (53.29%), Postives = 209/289 (72.32%), Query Frame = 3 
Query:  303 NSIKYRNQ-RRPHSLSISWNSPDSDRTDTISPALKRWFRAVSKICKHDDDIDPWHDFTIDTIKPDKAIRYRYSAIKKKWVQDEIWVKLETLPFDHGAMRECFRLKKLSTTGINNNHDWNFSSNYVAKQYINLVNRDVYFEDVKLQMESKLWAEEYNRQNPPKKIDIFQLSIIELIDRENKPLYHIEHFMEGTYLKYNSNSGYVDDSCLRNTPQAFSHFTFERSGHRIIIVDIQGVGDLYTDPQVHTAXXXXXXXXXXXXXXMALFFSSHRCNPICHYLGLSEFDMHQNE 1166
            NS  Y+N+ + P   S+ + S       T   A+++  RA+          DPW +F ++ ++ +  IRYRY+AI   WVQD++++K+ + PF  GAMREC+R KKLS    +++ +W  +SNYVAK+Y+  V+RDVYFEDV+LQME+KLW EEYNR  PPK++DI Q+ ++E+  R  KPLYH+EH++EG Y+KYNSNSG+V D  +R TPQAFSHFTFERSGH++I+VDIQGVGDLYTDPQ+HT  G ++GDGNLG+RGMALFF SH CN IC  +GL+ FD+   E
Sbjct:   76 NSFTYKNKNKEPEVRSVRFGSLTEKGRATWKHAIEK-ARAMP---------DPWAEFHLEEVETEPCIRYRYNAITGDWVQDQVFIKMSSQPFGKGAMRECYRTKKLSN--FSHSSNWKCASNYVAKRYMETVDRDVYFEDVRLQMEAKLWGEEYNRHRPPKQVDIMQMCVVEMASRPGKPLYHLEHYIEGQYIKYNSNSGFVRDDNIRLTPQAFSHFTFERSGHQLIVVDIQGVGDLYTDPQIHTEKGTDFGDGNLGVRGMALFFHSHLCNKICKSMGLTPFDVAPAE 352

HSP 2 Score: 93.9745 bits (232), Expect = 3.023e-19
Identity = 79/262 (30.15%), Postives = 126/262 (48.09%), Query Frame = 3 
Query: 1755 LDQEIGHSILAQVHHELARLHESGRFVKSKRLAPGCLHHQFWSNLLNENDSPEESEQKSPTNHDLDINWESCLFHERHAAQLGCLEAVIVMARYCLNMSGHMLQDCPLPPNQNDIECGLDYLWRAADSGDRRSMIELANLYRKTEYFGEIFNEINKTTLEVNWFEAVKWYKRAFEAVNKLDGQIDSKDAEGRYDSAEDLMPPQEILASMAELYLKGGYGLEKNCQLAGELYSQAAEIATNALQGRQAVKYYELADTAYSQDE 2540
            L+++IG S+L +VH  + R HE+GRF                     E D+P +               +S L+H   AA  G LEA++ + +  L +  H+L +  L  +  + + G  +L +AA++GDR SM+ +A        F    N  +  T   +W EAV+WY       +  +G        G +D  +D  P   +LA  AEL+  GG+ L  + Q AG+L+++AAE A  A++GR A +YY  A+ A+S  E
Sbjct:  548 LERKIGKSVLGKVHLAMVRYHEAGRFC--------------------EKDAPWDQ--------------KSALYHLERAAMCGELEAIVALGQCYLQLPHHILSELELEDSDENRKKGFRFLLQAAEAGDRPSMMLVARA------FDTGINLPSDRT--QDWEEAVQWYDCVLNMTDYDEG--------GEFDGMQD-DPRYLLLAREAELFQMGGFNLTADPQRAGDLFTEAAEAAMEAMKGRLANQYYMKAEEAWSAME 758
[Close]
BLAST of Elongation factor 2 kinase vs. Ensembl Cavefish
Match: eef2k (eukaryotic elongation factor 2 kinase [Source:NCBI gene;Acc:103031207])

HSP 1 Score: 305.064 bits (780), Expect = 6.748e-91
Identity = 143/238 (60.08%), Postives = 189/238 (79.41%), Query Frame = 3 
Query:  453 DPWHDFTIDTIKPDKAIRYRYSAIKKKWVQDEIWVKLETLPFDHGAMRECFRLKKLSTTGINNNHDWNFSSNYVAKQYINLVNRDVYFEDVKLQMESKLWAEEYNRQNPPKKIDIFQLSIIELIDRENKPLYHIEHFMEGTYLKYNSNSGYVDDSCLRNTPQAFSHFTFERSGHRIIIVDIQGVGDLYTDPQVHTAXXXXXXXXXXXXXXMALFFSSHRCNPICHYLGLSEFDMHQNE 1166
            DPW +F ++ ++ +  IRYRY+AI   WVQD++++K+ + PF  GAMREC+R KKLS    +++ +W  +SNYVAK+Y+  V+RDVYFEDV+LQME+KLW EEYNR  PPK++DI Q+ ++E+  R  KPLYH+EH++EG Y+KYNSNSG+V D  +R TPQAFSHFTFERSGH++I+VDIQGVGDLYTDPQ+HT  G ++GDGNLG+RGMALFF SH CN IC  +GL+ FD+   E
Sbjct:   96 DPWAEFHLEEVETEPCIRYRYNAITGDWVQDQVFIKMSSQPFGKGAMRECYRTKKLSN--FSHSSNWKCASNYVAKRYMETVDRDVYFEDVRLQMEAKLWGEEYNRHRPPKQVDIMQMCVVEMASRPGKPLYHLEHYIEGQYIKYNSNSGFVRDDNIRLTPQAFSHFTFERSGHQLIVVDIQGVGDLYTDPQIHTEKGTDFGDGNLGVRGMALFFHSHLCNKICKSMGLTPFDVAPAE 331

HSP 2 Score: 93.9745 bits (232), Expect = 3.188e-19
Identity = 79/262 (30.15%), Postives = 126/262 (48.09%), Query Frame = 3 
Query: 1755 LDQEIGHSILAQVHHELARLHESGRFVKSKRLAPGCLHHQFWSNLLNENDSPEESEQKSPTNHDLDINWESCLFHERHAAQLGCLEAVIVMARYCLNMSGHMLQDCPLPPNQNDIECGLDYLWRAADSGDRRSMIELANLYRKTEYFGEIFNEINKTTLEVNWFEAVKWYKRAFEAVNKLDGQIDSKDAEGRYDSAEDLMPPQEILASMAELYLKGGYGLEKNCQLAGELYSQAAEIATNALQGRQAVKYYELADTAYSQDE 2540
            L+++IG S+L +VH  + R HE+GRF                     E D+P +               +S L+H   AA  G LEA++ + +  L +  H+L +  L  +  + + G  +L +AA++GDR SM+ +A        F    N  +  T   +W EAV+WY       +  +G        G +D  +D  P   +LA  AEL+  GG+ L  + Q AG+L+++AAE A  A++GR A +YY  A+ A+S  E
Sbjct:  526 LERKIGKSVLGKVHLAMVRYHEAGRFC--------------------EKDAPWDQ--------------KSALYHLERAAMCGELEAIVALGQCYLQLPHHILSELELEDSDENRKKGFRFLLQAAEAGDRPSMMLVARA------FDTGINLPSDRT--QDWEEAVQWYDCVLNMTDYDEG--------GEFDGMQD-DPRYLLLAREAELFQMGGFNLTADPQRAGDLFTEAAEAAMEAMKGRLANQYYMKAEEAWSAME 736
[Close]
BLAST of Elongation factor 2 kinase vs. Ensembl Cavefish
Match: eef2k (eukaryotic elongation factor 2 kinase [Source:NCBI gene;Acc:103031207])

HSP 1 Score: 271.552 bits (693), Expect = 3.651e-79
Identity = 135/238 (56.72%), Postives = 176/238 (73.95%), Query Frame = 3 
Query:  453 DPWHDFTIDTIKPDKAIRYRYSAIKKKWVQDEIWVKLETLPFDHGAMRECFRLKKLSTTGINNNHDWNFSSNYVAKQYINLVNRDVYFEDVKLQMESKLWAEEYNRQNPPKKIDIFQLSIIELIDRENKPLYHIEHFMEGTYLKYNSNSGYVDDSCLRNTPQAFSHFTFERSGHRIIIVDIQGVGDLYTDPQVHTAXXXXXXXXXXXXXXMALFFSSHRCNPICHYLGLSEFDMHQNE 1166
            DPW +F ++ ++ +  IRYR   + +              PF  GAMREC+R KKLS    +++ +W  +SNYVAK+Y+  V+RDVYFEDV+LQME+KLW EEYNR  PPK++DI Q+ ++E+  R  KPLYH+EH++EG Y+KYNSNSG+V D  +R TPQAFSHFTFERSGH++I+VDIQGVGDLYTDPQ+HT  G ++GDGNLG+RGMALFF SH CN IC  +GL+ FD+   E
Sbjct:   96 DPWAEFHLEEVETEPCIRYRNIFLLQ--------------PFGKGAMRECYRTKKLSN--FSHSSNWKCASNYVAKRYMETVDRDVYFEDVRLQMEAKLWGEEYNRHRPPKQVDIMQMCVVEMASRPGKPLYHLEHYIEGQYIKYNSNSGFVRDDNIRLTPQAFSHFTFERSGHQLIVVDIQGVGDLYTDPQIHTEKGTDFGDGNLGVRGMALFFHSHLCNKICKSMGLTPFDVAPAE 317

HSP 2 Score: 93.5893 bits (231), Expect = 3.211e-19
Identity = 79/262 (30.15%), Postives = 126/262 (48.09%), Query Frame = 3 
Query: 1755 LDQEIGHSILAQVHHELARLHESGRFVKSKRLAPGCLHHQFWSNLLNENDSPEESEQKSPTNHDLDINWESCLFHERHAAQLGCLEAVIVMARYCLNMSGHMLQDCPLPPNQNDIECGLDYLWRAADSGDRRSMIELANLYRKTEYFGEIFNEINKTTLEVNWFEAVKWYKRAFEAVNKLDGQIDSKDAEGRYDSAEDLMPPQEILASMAELYLKGGYGLEKNCQLAGELYSQAAEIATNALQGRQAVKYYELADTAYSQDE 2540
            L+++IG S+L +VH  + R HE+GRF                     E D+P +               +S L+H   AA  G LEA++ + +  L +  H+L +  L  +  + + G  +L +AA++GDR SM+ +A        F    N  +  T   +W EAV+WY       +  +G        G +D  +D  P   +LA  AEL+  GG+ L  + Q AG+L+++AAE A  A++GR A +YY  A+ A+S  E
Sbjct:  463 LERKIGKSVLGKVHLAMVRYHEAGRFC--------------------EKDAPWDQ--------------KSALYHLERAAMCGELEAIVALGQCYLQLPHHILSELELEDSDENRKKGFRFLLQAAEAGDRPSMMLVARA------FDTGINLPSDRT--QDWEEAVQWYDCVLNMTDYDEG--------GEFDGMQD-DPRYLLLAREAELFQMGGFNLTADPQRAGDLFTEAAEAAMEAMKGRLANQYYMKAEEAWSAME 673
[Close]
BLAST of Elongation factor 2 kinase vs. Ensembl Nematostella
Match: EDO36975 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SH28])

HSP 1 Score: 261.151 bits (666), Expect = 2.471e-76
Identity = 140/276 (50.72%), Postives = 183/276 (66.30%), Query Frame = 3 
Query:  453 DPWHDFTI-DTIKPDKAIRYRYSAIKKKWVQDEIWVKLETLPFDHGAMRECFRLKKLSTTGINNNHDWNFSSNYVAKQYINLVNRDVYFEDVKLQMESKLWAEEYNRQNPPKKIDIFQLSIIELIDRENKPLYHIEHFMEGTYLKYNSNSGYV-DDSCLRNTPQAFSHFTFERSGHRIIIVDIQGVGDLYTDPQ--------VHTAXXXXXXXXXXXXXXMALFFSSHRCNP-ICHYLGLSEFDMHQNELVDNDLDQEI-ADHDISTISIDALPEE 1244
            DPW  F I D    + A+R+RY+AIKK WV+DEI +K+E++PFD GAMR C+RLKKLS    +NN  W  +SNYVAK YI  V+RD YFEDV+LQM++KLW EEYNR++PPKK+DIFQ  IIEL +R   PLYH+EHF+EGTY KYNSNSG+V  D  LR TPQAFSHFTFERSGH++I+VDIQ + ++ + P+        +  A  +N          +     +  C+  IC  LGL+EFD+   E  D  +D  I    D ST+   +L ++
Sbjct:   33 DPWAKFHIHDNCAMEIAVRHRYNAIKKSWVKDEIRIKMESVPFDQGAMRVCYRLKKLSNFSKHNN--WKHASNYVAKSYIEEVSRDQYFEDVRLQMDAKLWGEEYNRRDPPKKVDIFQTYIIELKERTGSPLYHLEHFIEGTYKKYNSNSGFVLRDETLRCTPQAFSHFTFERSGHQLIVVDIQAI-NMNSSPKQPRHLRVSISLAINMNSSPKQPRHLRLLPLTKTRLCHSRICKTLGLTEFDISAVE--DKRIDSAIQVIQDSSTVVKSSLEDQ 303

HSP 2 Score: 98.5969 bits (244), Expect = 2.738e-21
Identity = 66/247 (26.72%), Postives = 112/247 (45.34%), Query Frame = 3 
Query: 1776 SILAQVHHELARLHESGRFVKSKRLAPGCLHHQFWSNLLNENDSPEESEQKSPTNHDLDINWESCLFHERHAAQLGCLEAVIVMARYCLNMSGHMLQDCPLPPNQNDIECGLDYLWRAADSGDRRSMIELANLYRKTEYFGEIFNEINKTTLEVNWFEAVKWYKRAFEAVNKLDGQIDSKDAEGRYDSAEDLM---PPQEILASMAELYLKGGYGLEKNCQLAGELYSQAAEIATNALQGRQAVKYY 2507
            S+L +VH E+A+  E GRF                                     D + + ES +FH   AAQ G   A++ +A   L +   +++   +   + +   G++ + +AA+ GDR++M+ +A  Y      G        T ++ +W EAVKWY+ A + +++              D  E+ +   P   +L+  AELY  GG  LE++ Q AG+L+S A + A  A++G+ A KYY
Sbjct:  415 SVLGKVHLEMAKYGEIGRFTS-----------------------------------DREPDMESAMFHMEKAAQCGITTALVTLAEIYLQLPHDLMESATVQETEENTNKGVELMLQAAERGDRQAMLYMAKAYDTGYGLG--------TNMKRSWKEAVKWYQNAIDVIDE-------------DDLPENTLLDDPVHTLLSRQAELYFTGGPELERDPQCAGDLFSSAGDEAMAAMKGKLANKYY 605
[Close]
BLAST of Elongation factor 2 kinase vs. Ensembl Nematostella
Match: EDO40068 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S899])

HSP 1 Score: 64.6994 bits (156), Expect = 1.317e-11
Identity = 56/182 (30.77%), Postives = 96/182 (52.75%), Query Frame = 3 
Query:  663 SNYVAKQYINLVNRDVYFEDVKLQMESKLWAEEYNRQ----NPPKKIDIFQ---LSIIELIDRENK--PLYHIEHFMEGTYLKYNSNSGYV----DDSCLRNT--PQAFSHFTFERSGHRIIIVDIQG------VGDLYTDPQVHTAXXXXXXXXXXXXXXMALFFSSH--RCNPICHYLGL 1139
            + YVAKQY        Y +DV  QM ++ +  ++N++    +  K  ++F    +++++L +  N+   + +IE +M G + K  +N  +V    D + ++      AFSHFT++ S  +++IVDIQG           TDPQ+H+A    +G GN   +G+  F+S+    CN IC  LGL
Sbjct:   40 ARYVAKQYYEEQPIKQYQQDVLSQMTARSYVAQFNQKLFMLDRGKASNLFTFLPVALLQLFNNANEVEQVCNIEPYMSGEFTKLTNNLTFVRKDEDGNPVKGADLVLAFSHFTWQSSNGKLVIVDIQGWTPKGRGCTFLTDPQIHSAVYDCFGTGNWKQQGIDKFWSAMHPECNAICKLLGL 221
[Close]
BLAST of Elongation factor 2 kinase vs. Ensembl Nematostella
Match: EDO35977 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SJY5])

HSP 1 Score: 56.225 bits (134), Expect = 3.235e-8
Identity = 33/69 (47.83%), Postives = 44/69 (63.77%), Query Frame = 3 
Query:  936 QAFSHFTFERSGHRIIIVDIQGVGDLYTDPQVHT-AXXXXXXXXXXXXXXMALFFSSHRCNPICHYLGL 1139
            +AFSHFT+  +G + ++ DIQGV + YTDPQ+HT      YG GN G  G+ +F   H CN +C  LGL
Sbjct:  314 EAFSHFTYHITGGQELVCDIQGVNNDYTDPQIHTNPLTSRYGKGNFGPMGIHIFLKDHHCNSMCKALGL 382
[Close]
BLAST of Elongation factor 2 kinase vs. Ensembl Nematostella
Match: EDO27286 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7T9N8])

HSP 1 Score: 51.2174 bits (121), Expect = 6.450e-8
Identity = 40/111 (36.04%), Postives = 58/111 (52.25%), Query Frame = 3 
Query:  849 HIEHFMEGTYLKYNSNSGYVDDSCLRNTPQ------AFSHFTFERSGHRIIIVDIQGVG------DLYTDPQVHTAXXXXXXXXXXXXXXMALFFSSH--RCNPICHYLGL 1139
            +IE +M G + K  +N  +V      N  +      AFSHFT++ S  +++IVDIQG           TDPQ+H+A    +G GN   +G+  F+S+    CN IC  LGL
Sbjct:    1 NIEPYMSGEFTKLTNNLTFVRKDEDGNPVKGADLVLAFSHFTWQSSNGKLVIVDIQGWTPKGRGCTFLTDPQIHSAVYDCFGTGNWKQQGIDKFWSAMHPECNAICKLLGL 111
[Close]
BLAST of Elongation factor 2 kinase vs. Ensembl Medaka
Match: eef2k (eukaryotic elongation factor 2 kinase [Source:NCBI gene;Acc:101158311])

HSP 1 Score: 301.597 bits (771), Expect = 4.944e-90
Identity = 144/243 (59.26%), Postives = 189/243 (77.78%), Query Frame = 3 
Query:  453 DPWHDFTIDTIKPDKAIRYRYSAIKKKWVQDEIWVKLETLPFDHGAMRECFRLKKLSTTGINNNHDWNFSSNYVAKQYINLVNRDVYFEDVKLQMESKLWAEEYNRQNPPKKIDIFQLSIIELIDRENKPLYHIEHFMEGTYLKYNSNSGYVDDSCLRNTPQAFSHFTFERSGHRIIIVDIQGVGDLYTDPQVHTAXXXXXXXXXXXXXXMALFFSSHRCNPICHYLGLSEFDMHQNELVDND 1181
            DPW  F ++ I  +  +RYRY+AI  +W QD+I +K+ + PF  GAMRECFR KKLS    +++ +W  +SNYVAK+Y+  V+RDVYFEDV+LQME+KLW EEYNR  PPK++DI Q+ ++E+ +R  KPL+H+EH++EG Y+KYNSNSG+V D  +R TPQAFSHFTFERSGH++I+VDIQGVGDLYTDPQ+HT  G ++GDGNLG+RGMALFF SH CN IC  +GL+ FD+   E+   D
Sbjct:   99 DPWAQFHLEEIPTESCMRYRYNAITGEWHQDQIHIKMGSQPFGKGAMRECFRSKKLSN--FSHSSNWKSASNYVAKRYMQEVDRDVYFEDVRLQMEAKLWGEEYNRHRPPKQVDIMQMCVVEMTNRPGKPLFHLEHYIEGKYIKYNSNSGFVRDDNIRLTPQAFSHFTFERSGHQLIVVDIQGVGDLYTDPQIHTEKGTDFGDGNLGVRGMALFFHSHMCNKICKSMGLTPFDLSPEEMSQLD 339

HSP 2 Score: 95.5153 bits (236), Expect = 9.781e-20
Identity = 81/254 (31.89%), Postives = 119/254 (46.85%), Query Frame = 3 
Query: 1749 TNLDQEIGHSILAQVHHELARLHESGRFVKSKRLAPGCLHHQFWSNLLNENDSPEESEQKSPTNHDLDINWESCLFHERHAAQLGCLEAVIVMARYCLNMSGHMLQDCPLPPNQNDIECGLDYLWRAADSGDRRSMIELANLYRKTEYFGEIFNEINKTT-LEVNWFEAVKWYKRAFEAVNKLDGQIDSKDAEGRYDSAEDLMPPQEILASMAELYLKGGYGLEKNCQLAGELYSQAAEIATNALQGRQAVKYY 2507
            T L ++IG S L +VH  + R HE+GRF         C   + W          +ES               S +FH   AA  G LEA++ + +  L +  H+L D  L  N  +   G  YL +AA++GDR SMI +A  +            IN +   + +W EA+ WY  A          +   D  G +D  +D  P   +LA  AE+Y KGG+ L  + Q AG+L+++AAE A  A++GR A +YY
Sbjct:  484 TLLQKKIGQSNLGKVHLAMVRYHEAGRF---------CEKDEQW----------DES---------------SAMFHLERAALCGELEAIVALGQCYLRLPHHILPDMELEDNAGNRMKGFKYLLQAAEAGDRSSMIIVARAFDSG---------INLSADRKQDWAEAIHWYDSAL--------NMSDFDEGGEFDGTQD-EPRYLLLAREAEMYQKGGHNLAADPQRAGDLFTEAAEAAMAAMKGRLANQYY 685
[Close]
BLAST of Elongation factor 2 kinase vs. Ensembl Medaka
Match: eef2k (eukaryotic elongation factor 2 kinase [Source:NCBI gene;Acc:101158311])

HSP 1 Score: 301.982 bits (772), Expect = 9.682e-90
Identity = 144/243 (59.26%), Postives = 189/243 (77.78%), Query Frame = 3 
Query:  453 DPWHDFTIDTIKPDKAIRYRYSAIKKKWVQDEIWVKLETLPFDHGAMRECFRLKKLSTTGINNNHDWNFSSNYVAKQYINLVNRDVYFEDVKLQMESKLWAEEYNRQNPPKKIDIFQLSIIELIDRENKPLYHIEHFMEGTYLKYNSNSGYVDDSCLRNTPQAFSHFTFERSGHRIIIVDIQGVGDLYTDPQVHTAXXXXXXXXXXXXXXMALFFSSHRCNPICHYLGLSEFDMHQNELVDND 1181
            DPW  F ++ I  +  +RYRY+AI  +W QD+I +K+ + PF  GAMRECFR KKLS    +++ +W  +SNYVAK+Y+  V+RDVYFEDV+LQME+KLW EEYNR  PPK++DI Q+ ++E+ +R  KPL+H+EH++EG Y+KYNSNSG+V D  +R TPQAFSHFTFERSGH++I+VDIQGVGDLYTDPQ+HT  G ++GDGNLG+RGMALFF SH CN IC  +GL+ FD+   E+   D
Sbjct:   98 DPWAQFHLEEIPTESCMRYRYNAITGEWHQDQIHIKMGSQPFGKGAMRECFRSKKLSN--FSHSSNWKSASNYVAKRYMQEVDRDVYFEDVRLQMEAKLWGEEYNRHRPPKQVDIMQMCVVEMTNRPGKPLFHLEHYIEGKYIKYNSNSGFVRDDNIRLTPQAFSHFTFERSGHQLIVVDIQGVGDLYTDPQIHTEKGTDFGDGNLGVRGMALFFHSHMCNKICKSMGLTPFDLSPEEMSQLD 338

HSP 2 Score: 95.9005 bits (237), Expect = 7.498e-20
Identity = 97/325 (29.85%), Postives = 147/325 (45.23%), Query Frame = 3 
Query: 1560 YHHPYEIKTNLSQIINSRKLFR--RRQRNYSDGSDIDASLVSYEEHLAVYYSMKEN-QKPSSATHP-----TNLDQEIGHSILAQVHHELARLHESGRFVKSKRLAPGCLHHQFWSNLLNENDSPEESEQKSPTNHDLDINWESCLFHERHAAQLGCLEAVIVMARYCLNMSGHMLQDCPLPPNQNDIECGLDYLWRAADSGDRRSMIELANLYRKTEYFGEIFNEINKTT-LEVNWFEAVKWYKRAFEAVNKLDGQIDSKDAEGRYDSAEDLMPPQEILASMAELYLKGGYGLEKNCQLAGELYSQAAEIATNALQGRQAVKYY 2507
            YH PY      S  I  +K+    R   N++  S I  +L   +E  + ++S + +  +PS          T L ++IG S L +VH  + R HE+GRF         C   + W          +ES               S +FH   AA  G LEA++ + +  L +  H+L D  L  N  +   G  YL +AA++GDR SMI +A  +            IN +   + +W EA+ WY  A          +   D  G +D  +D  P   +LA  AE+Y KGG+ L  + Q AG+L+++AAE A  A++GR A +YY
Sbjct:  462 YHRPYSESDEDS--IRRKKMVAPPRVSANFNSCSPIYEALT--DEKWSFFHSSRSHVHRPSCVATEVERLNTLLQKKIGQSNLGKVHLAMVRYHEAGRF---------CEKDEQW----------DES---------------SAMFHLERAALCGELEAIVALGQCYLRLPHHILPDMELEDNAGNRMKGFKYLLQAAEAGDRSSMIIVARAFDSG---------INLSADRKQDWAEAIHWYDSAL--------NMSDFDEGGEFDGTQD-EPRYLLLAREAEMYQKGGHNLAADPQRAGDLFTEAAEAAMAAMKGRLANQYY 730
[Close]
BLAST of Elongation factor 2 kinase vs. Ensembl Medaka
Match: eef2k (eukaryotic elongation factor 2 kinase [Source:NCBI gene;Acc:101158311])

HSP 1 Score: 302.368 bits (773), Expect = 1.060e-89
Identity = 144/243 (59.26%), Postives = 189/243 (77.78%), Query Frame = 3 
Query:  453 DPWHDFTIDTIKPDKAIRYRYSAIKKKWVQDEIWVKLETLPFDHGAMRECFRLKKLSTTGINNNHDWNFSSNYVAKQYINLVNRDVYFEDVKLQMESKLWAEEYNRQNPPKKIDIFQLSIIELIDRENKPLYHIEHFMEGTYLKYNSNSGYVDDSCLRNTPQAFSHFTFERSGHRIIIVDIQGVGDLYTDPQVHTAXXXXXXXXXXXXXXMALFFSSHRCNPICHYLGLSEFDMHQNELVDND 1181
            DPW  F ++ I  +  +RYRY+AI  +W QD+I +K+ + PF  GAMRECFR KKLS    +++ +W  +SNYVAK+Y+  V+RDVYFEDV+LQME+KLW EEYNR  PPK++DI Q+ ++E+ +R  KPL+H+EH++EG Y+KYNSNSG+V D  +R TPQAFSHFTFERSGH++I+VDIQGVGDLYTDPQ+HT  G ++GDGNLG+RGMALFF SH CN IC  +GL+ FD+   E+   D
Sbjct:  114 DPWAQFHLEEIPTESCMRYRYNAITGEWHQDQIHIKMGSQPFGKGAMRECFRSKKLSN--FSHSSNWKSASNYVAKRYMQEVDRDVYFEDVRLQMEAKLWGEEYNRHRPPKQVDIMQMCVVEMTNRPGKPLFHLEHYIEGKYIKYNSNSGFVRDDNIRLTPQAFSHFTFERSGHQLIVVDIQGVGDLYTDPQIHTEKGTDFGDGNLGVRGMALFFHSHMCNKICKSMGLTPFDLSPEEMSQLD 354

HSP 2 Score: 95.9005 bits (237), Expect = 7.957e-20
Identity = 97/325 (29.85%), Postives = 147/325 (45.23%), Query Frame = 3 
Query: 1560 YHHPYEIKTNLSQIINSRKLFR--RRQRNYSDGSDIDASLVSYEEHLAVYYSMKEN-QKPSSATHP-----TNLDQEIGHSILAQVHHELARLHESGRFVKSKRLAPGCLHHQFWSNLLNENDSPEESEQKSPTNHDLDINWESCLFHERHAAQLGCLEAVIVMARYCLNMSGHMLQDCPLPPNQNDIECGLDYLWRAADSGDRRSMIELANLYRKTEYFGEIFNEINKTT-LEVNWFEAVKWYKRAFEAVNKLDGQIDSKDAEGRYDSAEDLMPPQEILASMAELYLKGGYGLEKNCQLAGELYSQAAEIATNALQGRQAVKYY 2507
            YH PY      S  I  +K+    R   N++  S I  +L   +E  + ++S + +  +PS          T L ++IG S L +VH  + R HE+GRF         C   + W          +ES               S +FH   AA  G LEA++ + +  L +  H+L D  L  N  +   G  YL +AA++GDR SMI +A  +            IN +   + +W EA+ WY  A          +   D  G +D  +D  P   +LA  AE+Y KGG+ L  + Q AG+L+++AAE A  A++GR A +YY
Sbjct:  478 YHRPYSESDEDS--IRRKKMVAPPRVSANFNSCSPIYEALT--DEKWSFFHSSRSHVHRPSCVATEVERLNTLLQKKIGQSNLGKVHLAMVRYHEAGRF---------CEKDEQW----------DES---------------SAMFHLERAALCGELEAIVALGQCYLRLPHHILPDMELEDNAGNRMKGFKYLLQAAEAGDRSSMIIVARAFDSG---------INLSADRKQDWAEAIHWYDSAL--------NMSDFDEGGEFDGTQD-EPRYLLLAREAEMYQKGGHNLAADPQRAGDLFTEAAEAAMAAMKGRLANQYY 746
[Close]
BLAST of Elongation factor 2 kinase vs. Ensembl Medaka
Match: trpm6 (transient receptor potential cation channel subfamily M member 6 [Source:NCBI gene;Acc:101159200])

HSP 1 Score: 63.929 bits (154), Expect = 8.641e-10
Identity = 44/108 (40.74%), Postives = 59/108 (54.63%), Query Frame = 3 
Query:  852 IEHFMEGTYLKYNSNSGYVDDSC--LRNTPQAFSHFTFERSGHRIIIVDIQGVGDLYTDPQVHTAXXXXXXXX-------XXXXXXMALFFSSHRCNPICHYLGLSEF 1148
            IE  M G + KYN+N+G     C  L +   AFSH+T+E S   ++++DIQGVG+  TDP V  AD  + G G       NLG+  +  F   H CN  CH LGL + 
Sbjct: 1845 IERNMTGDFRKYNNNTGEEITPCSSLEDMLLAFSHWTYEHSCKELLVLDIQGVGEELTDPTVIMADDQSGGKGDLLFGPDNLGVAAINGFLQKHTCNLCCHRLGLKDL 1952
[Close]
BLAST of Elongation factor 2 kinase vs. Ensembl Medaka
Match: trpm6 (transient receptor potential cation channel subfamily M member 6 [Source:NCBI gene;Acc:101159200])

HSP 1 Score: 63.1586 bits (152), Expect = 1.307e-9
Identity = 44/105 (41.90%), Postives = 58/105 (55.24%), Query Frame = 3 
Query:  852 IEHFMEGTYLKYNSNSGYVDDSC--LRNTPQAFSHFTFERSGHRIIIVDIQGVGDLYTDPQVHTAXXXXXXXX-------XXXXXXMALFFSSHRCNPICHYLGL 1139
            IE  M G + KYN+N+G     C  L +   AFSH+T+E S   ++++DIQGVG+  TDP V  AD  + G G       NLG+  +  F   H CN  CH LGL
Sbjct: 1845 IERNMTGDFRKYNNNTGEEITPCSSLEDMLLAFSHWTYEHSCKELLVLDIQGVGEELTDPTVIMADDQSGGKGDLLFGPDNLGVAAINGFLQKHTCNLCCHRLGL 1949
[Close]
BLAST of Elongation factor 2 kinase vs. Planmine SMEST
Match: SMESG000034660.1 (SMESG000034660.1)

HSP 1 Score: 1555.42 bits (4026), Expect = 0.000e+0
Identity = 780/783 (99.62%), Postives = 782/783 (99.87%), Query Frame = 3 
Query:  201 MDEDIESCEDTNFSELLNSLECNTELDDFALYSVNSIKYRNQRRPHSLSISWNSPDSDRTDTISPALKRWFRAVSKICKHDDDIDPWHDFTIDTIKPDKAIRYRYSAIKKKWVQDEIWVKLETLPFDHGAMRECFRLKKLSTTGINNNHDWNFSSNYVAKQYINLVNRDVYFEDVKLQMESKLWAEEYNRQNPPKKIDIFQLSIIELIDRENKPLYHIEHFMEGTYLKYNSNSGYVDDSCLRNTPQAFSHFTFERSGHRIIIVDIQGVGDLYTDPQVHTAXXXXXXXXXXXXXXMALFFSSHRCNPICHYLGLSEFDMHQNELVDNDLDQEIADHDISTISIDALPEEDSCAFSSKSYNEIKKRNRSISFKMSGTVIRDGRTSPCVTSPAFLDQLFPAPIDLIRAMSVDSGVQSVSTPFVSQGNFMTXXXXXXXXXXXXXXXXXXXXHSGLGAYHHPYEIKTNLSQIINSRKLFRRRQRNYSDGSDIDASLVSYEEHLAVYYSMKENQKPSSATHPTNLDQEIGHSILAQVHHELARLHESGRFVKSKRLAPGCLHHQFWSNLLNENDSPEESEQKSPTNHDLDINWESCLFHERHAAQLGCLEAVIVMARYCLNMSGHMLQDCPLPPNQNDIECGLDYLWRAADSGDRRSMIELANLYRKTEYFGEIFNEINKTTLEVNWFEAVKWYKRAFEAVNKLDGQIDSKDAEGRYDSAEDLMPPQEILASMAELYLKGGYGLEKNCQLAGELYSQAAEIATNALQGRQAVKYYELADTAYSQDENCE 2549
            MDEDIESCEDTNFSELLNSLECNTELDD ALYSVNSIKYRNQRRPHSLSISWNSPDSDRTDTISPALKRWFRAVSKICKHDDDIDPWHDFTIDTIKPDKAIRYRYSAIKKKWVQDEIWVKLETLPFDHGAMRECFRLKKLSTTGINNNHDWNFSSNYVAKQYINLVNRDVYFEDVKLQMESKLWAEEYNRQNPPKKIDIFQLSIIELIDRENKPLYHIEHFMEGTYLKYNSNSGYVDDSCLRNTPQAFSHFTFERSGHRIIIVDIQGVGDLYTDPQVHTADGLNYGDGNLGLRGMALFFSSHRCNPICH+LGLSEFDMHQNELVDNDLDQEIADHDISTISIDALPEEDSCAFSSKSYNEIKKRNRSISFKMSGTVIRDGRTSPCVTSPAFLDQLFPAPIDLIRAMSVDSGVQSVSTPFVSQGNFMTSSIVQSDDSLSSVISGSNGLHSGLGAYHHPYEIKTNLSQIINSRKLFRRRQRNYSDGSDIDASLVSYEEHLAVY+SMKENQKPSSATHPTNLDQEIGHSILAQVHHELARLHESGRFVKSKRLAPGCLHHQFWSNLLNENDSPEESEQKSPTNHDLDINWESCLFHERHAAQLGCLEAVIVMARYCLNMSGHMLQDCPLPPNQNDIECGLDYLWRAADSGDRRSMIELANLYRKTEYFGEIFNEINKTTLEVNWFEAVKWYKRAFEAVNKLDGQIDSKDAEGRYDSAEDLMPPQEILASMAELYLKGGYGLEKNCQLAGELYSQAAEIATNALQGRQAVKYYELADTAYSQDENCE
Sbjct:    1 MDEDIESCEDTNFSELLNSLECNTELDDLALYSVNSIKYRNQRRPHSLSISWNSPDSDRTDTISPALKRWFRAVSKICKHDDDIDPWHDFTIDTIKPDKAIRYRYSAIKKKWVQDEIWVKLETLPFDHGAMRECFRLKKLSTTGINNNHDWNFSSNYVAKQYINLVNRDVYFEDVKLQMESKLWAEEYNRQNPPKKIDIFQLSIIELIDRENKPLYHIEHFMEGTYLKYNSNSGYVDDSCLRNTPQAFSHFTFERSGHRIIIVDIQGVGDLYTDPQVHTADGLNYGDGNLGLRGMALFFSSHRCNPICHFLGLSEFDMHQNELVDNDLDQEIADHDISTISIDALPEEDSCAFSSKSYNEIKKRNRSISFKMSGTVIRDGRTSPCVTSPAFLDQLFPAPIDLIRAMSVDSGVQSVSTPFVSQGNFMTSSIVQSDDSLSSVISGSNGLHSGLGAYHHPYEIKTNLSQIINSRKLFRRRQRNYSDGSDIDASLVSYEEHLAVYHSMKENQKPSSATHPTNLDQEIGHSILAQVHHELARLHESGRFVKSKRLAPGCLHHQFWSNLLNENDSPEESEQKSPTNHDLDINWESCLFHERHAAQLGCLEAVIVMARYCLNMSGHMLQDCPLPPNQNDIECGLDYLWRAADSGDRRSMIELANLYRKTEYFGEIFNEINKTTLEVNWFEAVKWYKRAFEAVNKLDGQIDSKDAEGRYDSAEDLMPPQEILASMAELYLKGGYGLEKNCQLAGELYSQAAEIATNALQGRQAVKYYELADTAYSQDENCE 783
[Close]
BLAST of Elongation factor 2 kinase vs. Planmine SMEST
Match: SMESG000014704.1 (SMESG000014704.1)

HSP 1 Score: 289.656 bits (740), Expect = 1.002e-85
Identity = 167/328 (50.91%), Postives = 216/328 (65.85%), Query Frame = 3 
Query:  201 MDEDIESCEDTNFSELL-NSLECNTELDDFALYSVNSIKYRNQRRPHSLSISWNSPDSDRTDTISPALK---RWFRAVSKICKHDDDIDPWHDFTIDTIKPDKAIRYRYSAIKKKWVQDEIWVKLETLPFDHGAMRECFRLKKLSTTGINNNHDWNFSSNYVAKQYINLVNRDVYFEDVKLQMESKLWAEEYNRQNPPKK-IDIFQLSIIELIDRENKPLYHIEHFMEGTYLKYNSNSGYVDDSCLRNTPQAFSHFTFERSGHRIIIVDIQGVGDLYTDPQVHTAXXXXXXXXXXXXXXMALFFSSHRCNPICHYLGLSEFDMHQNEL 1169
            ++E++   ED+  SELL N ++C   +      SVN  K +  +  HS+ +     +S   D     LK    W     +     D   P+  F +  +  +K IRY Y +I K W  D+  VK+E  PF+ GAMRECFRLKK+ST   N   DW  + N+V+K+Y+  V R+VYFEDV LQM++KLWAEE+NRQ   KK +DI ++SIIE  DR +KPLYH+EHF+EG Y+KYNSNSG+VDD   RNTPQAFSHFTFERSGH +I+VDIQGVGDLYTDPQ+HT+    YG+GNLG RGMALFF SH CN +C  LGL+ FD+  +EL
Sbjct:    2 INEELAEDEDSIDSELLRNVVKCEENVPKRRRMSVNVFKLKKSQ--HSIDVDHLKSESMSNDDSIKHLKVPKLWQSLARRTLMLSD---PFRTFKLSELPTEKVIRYLYDSITKSWKTDKAIVKMEKEPFNRGAMRECFRLKKISTFHGN---DWKRAGNFVSKRYMENVEREVYFEDVCLQMDAKLWAEEFNRQPGVKKEVDIVRMSIIEFSDRPDKPLYHLEHFIEGNYIKYNSNSGFVDDRN-RNTPQAFSHFTFERSGHELIVVDIQGVGDLYTDPQIHTSCRNGYGNGNLGPRGMALFFHSHICNNVCEALGLARFDLAPSEL 320

HSP 2 Score: 141.354 bits (355), Expect = 2.288e-34
Identity = 90/290 (31.03%), Postives = 144/290 (49.66%), Query Frame = 3 
Query: 1683 EEHLAVYYSMKENQKPSSATHPTNLDQEIGHSILAQVHHELARLHESGRFVKSKRLAPGCLHHQFWSNLLNENDSPEESEQKSPTNHDLDINWESCLFHERHAAQLGCLEAVIVMARYCLNMSGH-MLQDCPLPPNQNDIECGLDYLWRAADSGDRRSMIELANLYRKTEYFGEIFNEINKTTL---EVNWFEAVKWYKRAFEAVNKLDGQIDSKDAEGRYDSAEDLMPPQEILASMAELYLKGGYGLEKNCQLAGELYSQAAEIATNALQGRQAVKYYELADTAYSQDE 2540
            E+ L  Y +     +PS A    +    +G SIL ++HHE++ +HE GRF    +L                 D P              INWE+ L+HE  AA L C+EA++ MA Y L +    +L+ C + P+      G  YL +AA++G R S++ LA+            N++ ++ +   + +W   + W +R  E +++LD         G +DS  D  P   + A MA ++  GGYGL+K+ + + ELYS+A + AT A++GR A KYYEL++  Y + E
Sbjct:  455 EDSLDAYMNRNHIHRPSCAVSTDSCSLRMGESILGEIHHEISNMHEIGRFADRNQL-----------------DEP--------------INWEAVLYHEDLAASLNCMEAILNMANYHLGLPPRDLLKACTIQPDPEKKFKGWIYLTKAANAGHRPSIMALADA-----------NDVEQSKIHGSDPDWSSVMHWLERTVETIDQLD-------ENGEFDSTND-NPSYVVKARMAAMFRTGGYGLDKDTERSAELYSEAGDEATAAMKGRLASKYYELSEEVYGEME 694
[Close]
BLAST of Elongation factor 2 kinase vs. Planmine SMEST
Match: SMESG000020757.1 (SMESG000020757.1)

HSP 1 Score: 281.952 bits (720), Expect = 4.404e-83
Identity = 149/262 (56.87%), Postives = 194/262 (74.05%), Query Frame = 3 
Query:  396 ALKRWFRAVSKICKHDDDIDPWHDFTIDTIKPDKAIRYRYSAIKKKWVQD-EIWVKLETLPFDHGAMRECFRLKKLSTTGINNNHDWNFSSNYVAKQYINLVNRDVYFEDVKLQMESKLWAEEYNRQ-NPPKKIDIFQLSIIELIDRENKPLYHIEHFMEGTYLKYNSNSGYVDDSCLRNTPQAFSHFTFERSGHRIIIVDIQGVGDLYTDPQVHTAXXXXXXXXXXXXXXMALFFSSHRCNPICHYLGLSEFDMHQNELVD 1175
            ++ RW  A+ K  K  D   PW +F +D I  +K  RY +++    W+Q  E  VK+E+ PF+ GAMRECFRLKK+S+       DW  + NYVAK+YI  V+  VY+EDVKLQM++KLW +EY+RQ    KK+DI Q+S+I+ +DR  +PLYH+EHF+EG Y+KYNSNSG+VD++  RNTPQAFSHFTFERSGH++I+VDIQGVGDLYTDPQ+HT   ++YGDGNLG RGMALFF SH CN IC  LGL +FD+ ++E  D
Sbjct:   81 SIDRWKSALIKFKKLKD---PWKNFDLDKIISEKVERYIFNSFTGLWLQSVEYKVKMESKPFNRGAMRECFRLKKMSSL-FKEEKDWYRAGNYVAKRYIEPVDGSVYYEDVKLQMDAKLWGQEYSRQPGVIKKVDICQMSVIKFVDRPGQPLYHLEHFIEGDYIKYNSNSGFVDENS-RNTPQAFSHFTFERSGHKLIVVDIQGVGDLYTDPQIHTFAKIDYGDGNLGPRGMALFFHSHVCNAICSILGLQKFDLSKSESED 337

HSP 2 Score: 140.198 bits (352), Expect = 5.051e-34
Identity = 91/253 (35.97%), Postives = 127/253 (50.20%), Query Frame = 3 
Query: 1779 ILAQVHHELARLHESGRFVKSKRLAPGCLHHQFWSNLLNENDSPEESEQKSPTNHDLDINWESCLFHERHAAQLGCLEAVIVMARYCLNMS-GHMLQDCPLPPNQNDIECGLDYLWRAADSGDRRSMIELANLYRKTEYFGEIFNEINKTTLEVNWFEAVKWYKRAFEAVNKLDGQIDSKDAEGRYDSAEDLMPPQEILASMAELYLKGGYGLEKNCQLAGELYSQAAEIATNALQGRQAVKYYELADTAYSQ 2534
            IL ++HHELARLH SG+F+   ++                                 +INWE  LFHE  AA+LG LE++  ++R+ L++    + ++C     + D E GL Y+  AA+ GDRRSMI L + YRK   F              NW+EA KWY+ A  +        +  D  G +DS  D+ P  EI A MAE+   GG GL+K+   A  LYSQAA+ AT A  GR A KY+ +A+   S+
Sbjct:  475 ILGEIHHELARLHSSGKFITDNKIQ--------------------------------NINWEVVLFHEELAAKLGYLESMCNLSRFYLDIDRDSLFENCLFKLTEMDKEKGLQYMIMAAEYGDRRSMIFLGDHYRKEPQFH-------------NWYEAYKWYECAITSA-------EDSDISGGFDSVADV-PLFEIKARMAEIKYIGGNGLDKDLNSAYNLYSQAADHATMAGNGRCATKYFTIAEEILSK 674
[Close]
BLAST of Elongation factor 2 kinase vs. Planmine SMEST
Match: SMESG000077033.1 (SMESG000077033.1)

HSP 1 Score: 225.713 bits (574), Expect = 4.299e-64
Identity = 115/177 (64.97%), Postives = 145/177 (81.92%), Query Frame = 3 
Query:  648 DWNFSSNYVAKQYINLVNRDVYFEDVKLQMESKLWAEEYNRQ-NPPKKIDIFQLSIIELIDRENKPLYHIEHFMEGTYLKYNSNSGYVDDSCLRNTPQAFSHFTFERSGHRIIIVDIQGVGDLYTDPQVHTAXXXXXXXXXXXXXXMALFFSSHRCNPICHYLGLSEFDMHQNELVD 1175
            DW  + NYVAK+YI  V+  VY+EDVKLQM++KLW +EY+RQ    KK+DI Q+S+I+ +DR  +PLYH+EHF+EG Y+KYNSNSG+VD++  RNTPQAFSHFTFERSGH++I+VDIQGVGDLYTDPQ+HT   ++YGDGNLG RGMALFF SH CN IC  LGL +FD+ ++E  D
Sbjct:   10 DWYRAGNYVAKRYIEPVDGSVYYEDVKLQMDAKLWGQEYSRQPGVIKKVDICQMSVIKFVDRPGQPLYHLEHFIEGDYIKYNSNSGFVDENS-RNTPQAFSHFTFERSGHKLIVVDIQGVGDLYTDPQIHTFAKIDYGDGNLGPRGMALFFHSHVCNAICSILGLQKFDLSKSESED 185

HSP 2 Score: 139.043 bits (349), Expect = 2.912e-34
Identity = 90/253 (35.57%), Postives = 128/253 (50.59%), Query Frame = 3 
Query: 1779 ILAQVHHELARLHESGRFVKSKRLAPGCLHHQFWSNLLNENDSPEESEQKSPTNHDLDINWESCLFHERHAAQLGCLEAVIVMARYCLNMS-GHMLQDCPLPPNQNDIECGLDYLWRAADSGDRRSMIELANLYRKTEYFGEIFNEINKTTLEVNWFEAVKWYKRAFEAVNKLDGQIDSKDAEGRYDSAEDLMPPQEILASMAELYLKGGYGLEKNCQLAGELYSQAAEIATNALQGRQAVKYYELADTAYSQ 2534
            IL ++HHELARLH SG+F+   ++                                 +INWE+ LFHE  AA+LG LE++  ++R+ L++    + ++C     + D E GL Y+  AA+ GDRRSMI L + YRK   F              NW+EA KWY+ A  +        +  D  G +DS  D+ P  EI A MAE+   GG GL+++   A  LYSQAA+ AT A  GR A KY+ +A+   S+
Sbjct:  323 ILGEIHHELARLHSSGKFITDNKIQ--------------------------------NINWEAVLFHEELAAKLGYLESMCNLSRFYLDIDRDSLFENCLFKLTEMDKEKGLQYMIMAAEYGDRRSMIFLGDHYRKEPQFH-------------NWYEAYKWYECAITSA-------EDSDISGGFDSVADV-PLFEIKARMAEIKYIGGNGLDQDLNSAYNLYSQAADHATMAGNGRCATKYFTIAEEILSK 522
The following BLAST results are available for this feature:
BLAST of Elongation factor 2 kinase vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5
Match NameE-valueIdentityDescription
EEF2K2.800e-9459.68eukaryotic elongation factor 2 kinase [Source:HGNC... [more]
EEF2K2.242e-9059.68eukaryotic elongation factor 2 kinase [Source:HGNC... [more]
EEF2K2.242e-9059.68eukaryotic elongation factor 2 kinase [Source:HGNC... [more]
EEF2K2.360e-9059.68eukaryotic elongation factor 2 kinase [Source:HGNC... [more]
ALPK12.500e-1225.52alpha kinase 1 [Source:HGNC Symbol;Acc:HGNC:20917][more]
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BLAST of Elongation factor 2 kinase vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 2
Match NameE-valueIdentityDescription
efk-14.208e-8760.80Eukaryotic elongation factor 2 kinase [Source:Uni... [more]
efk-15.668e-8760.80Eukaryotic elongation factor 2 kinase [Source:Uni... [more]
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BLAST of Elongation factor 2 kinase vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Elongation factor 2 kinase vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
eef2k6.972e-11935.14eukaryotic elongation factor 2 kinase [Source:ZFIN... [more]
eef2k7.519e-9056.85eukaryotic elongation factor 2 kinase [Source:ZFIN... [more]
trpm67.147e-828.21transient receptor potential cation channel, subfa... [more]
trpm71.361e-730.83transient receptor potential cation channel, subfa... [more]
trpm72.547e-730.83transient receptor potential cation channel, subfa... [more]
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BLAST of Elongation factor 2 kinase vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5
Match NameE-valueIdentityDescription
neu45.262e-11736.74neuraminidase 4 (sialidase) [Source:Xenbase;Acc:XB... [more]
neu46.575e-9258.61neuraminidase 4 (sialidase) [Source:Xenbase;Acc:XB... [more]
neu41.113e-8858.61neuraminidase 4 (sialidase) [Source:Xenbase;Acc:XB... [more]
neu41.571e-8858.61neuraminidase 4 (sialidase) [Source:Xenbase;Acc:XB... [more]
neu41.693e-8858.61neuraminidase 4 (sialidase) [Source:Xenbase;Acc:XB... [more]
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BLAST of Elongation factor 2 kinase vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Eef2k2.011e-8857.41eukaryotic elongation factor-2 kinase [Source:MGI ... [more]
Eef2k2.011e-8857.41eukaryotic elongation factor-2 kinase [Source:MGI ... [more]
Eef2k2.011e-8857.41eukaryotic elongation factor-2 kinase [Source:MGI ... [more]
Eef2k1.110e-1639.58eukaryotic elongation factor-2 kinase [Source:MGI ... [more]
Eef2k2.062e-1440.66eukaryotic elongation factor-2 kinase [Source:MGI ... [more]
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BLAST of Elongation factor 2 kinase vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|O00418|EF2K_HUMAN1.134e-8959.68Eukaryotic elongation factor 2 kinase OS=Homo sapi... [more]
sp|P70531|EF2K_RAT2.471e-8857.79Eukaryotic elongation factor 2 kinase OS=Rattus no... [more]
sp|O08796|EF2K_MOUSE1.407e-8757.41Eukaryotic elongation factor 2 kinase OS=Mus muscu... [more]
sp|O01991|EF2K_CAEEL7.210e-8660.80Eukaryotic elongation factor 2 kinase OS=Caenorhab... [more]
sp|Q54DK4|AK1_DICDI2.512e-5351.13Alpha-protein kinase 1 OS=Dictyostelium discoideum... [more]
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BLAST of Elongation factor 2 kinase vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
A0A0R3ST811.327e-16342.12Alpha-type protein kinase domain-containing protei... [more]
A0A293M2511.401e-13139.26Alpha-type protein kinase domain-containing protei... [more]
K1RAD51.881e-13038.80Eukaryotic elongation factor 2 kinase OS=Crassostr... [more]
A0A2R5LEC77.877e-12938.10Putative elongation factor 2 kinase ixodes scapula... [more]
A0A131XNL12.898e-12838.71Putative elongation factor 2 kinase (Fragment) OS=... [more]
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BLAST of Elongation factor 2 kinase vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
eef2k9.579e-11635.50eukaryotic elongation factor 2 kinase [Source:NCBI... [more]
eef2k2.066e-9153.29eukaryotic elongation factor 2 kinase [Source:NCBI... [more]
eef2k4.438e-9153.29eukaryotic elongation factor 2 kinase [Source:NCBI... [more]
eef2k6.748e-9160.08eukaryotic elongation factor 2 kinase [Source:NCBI... [more]
eef2k3.651e-7956.72eukaryotic elongation factor 2 kinase [Source:NCBI... [more]
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BLAST of Elongation factor 2 kinase vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Elongation factor 2 kinase vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Elongation factor 2 kinase vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 4
Match NameE-valueIdentityDescription
EDO369752.471e-7650.72Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO400681.317e-1130.77Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO359773.235e-847.83Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO272866.450e-836.04Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
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BLAST of Elongation factor 2 kinase vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5
Match NameE-valueIdentityDescription
eef2k4.944e-9059.26eukaryotic elongation factor 2 kinase [Source:NCBI... [more]
eef2k9.682e-9059.26eukaryotic elongation factor 2 kinase [Source:NCBI... [more]
eef2k1.060e-8959.26eukaryotic elongation factor 2 kinase [Source:NCBI... [more]
trpm68.641e-1040.74transient receptor potential cation channel subfam... [more]
trpm61.307e-941.90transient receptor potential cation channel subfam... [more]
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BLAST of Elongation factor 2 kinase vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 4
Match NameE-valueIdentityDescription
SMESG000034660.10.000e+099.62SMESG000034660.1[more]
SMESG000014704.11.002e-8550.91SMESG000014704.1[more]
SMESG000020757.14.404e-8356.87SMESG000020757.1[more]
SMESG000077033.14.299e-6464.97SMESG000077033.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30013397 ID=SMED30013397|Name=Elongation factor 2 kinase|organism=Schmidtea mediterranea sexual|type=transcript|length=2717bp
GTTGAGTTCAAATAAATAGAAGCCATTGAAATTAATTGCTACTTTTTTCT
GTTTAACTTTTGCTTAAATAAGTGTTATTGTCACGCAAATTCGGCCGATA
ATTTGACCGACTGCGTATTATTGTGGTAGTTAAATTGAGATTTCATGTCT
ATATTTCTTTATAAAAATAAATTATCATTACGAGGTCGTTATACGTTAAT
ATGGACGAAGATATTGAATCTTGCGAAGATACAAATTTTTCAGAGTTACT
CAATTCGTTAGAATGCAACACCGAACTTGATGATTTTGCATTGTATTCAG
TTAATAGTATTAAATATCGAAATCAGCGTAGACCACATTCATTATCGATT
TCCTGGAATTCCCCGGATTCAGATAGAACAGATACAATTTCTCCAGCCCT
TAAAAGATGGTTTAGAGCCGTTTCTAAAATTTGCAAGCATGATGATGACA
TTGATCCATGGCATGATTTTACAATCGATACTATTAAGCCGGATAAAGCA
ATTCGATATCGTTATAGTGCTATTAAAAAGAAATGGGTTCAAGATGAAAT
ATGGGTTAAATTAGAAACCCTTCCCTTCGATCATGGAGCCATGAGAGAAT
GCTTTAGACTAAAAAAGCTCTCGACTACTGGGATTAACAACAATCACGAT
TGGAACTTTTCATCCAATTATGTGGCAAAACAATATATAAATCTAGTTAA
TCGTGATGTTTATTTTGAAGATGTCAAGCTACAAATGGAATCGAAACTTT
GGGCTGAAGAATATAACCGACAAAATCCCCCAAAAAAAATCGACATTTTC
CAGCTATCGATAATAGAATTGATTGACCGCGAAAATAAACCACTGTATCA
TATTGAGCATTTCATGGAAGGTACCTATTTGAAGTATAACTCTAATTCCG
GTTATGTGGATGATAGTTGCTTGAGAAATACTCCACAAGCCTTTAGTCAT
TTTACTTTTGAAAGGTCTGGGCATAGAATTATTATTGTAGACATTCAAGG
TGTTGGTGATCTTTATACAGATCCACAGGTTCACACGGCAGATGGATTAA
ACTATGGTGATGGGAATCTAGGCCTAAGAGGAATGGCGCTATTTTTTAGT
AGTCATAGATGCAATCCAATTTGTCATTATCTAGGATTAAGTGAATTTGA
TATGCATCAAAATGAATTAGTTGACAATGATCTCGATCAAGAAATTGCTG
ATCATGACATATCAACTATATCAATAGATGCACTTCCCGAAGAGGATTCT
TGTGCTTTTTCATCTAAAAGTTACAATGAAATTAAGAAAAGAAATCGGTC
CATTTCTTTTAAAATGTCTGGGACAGTAATCAGAGATGGTCGAACTTCTC
CATGTGTCACATCTCCCGCGTTTCTAGATCAATTGTTTCCTGCACCCATT
GACTTGATTCGAGCAATGTCTGTTGATTCTGGAGTACAGTCTGTCTCTAC
TCCCTTTGTCTCTCAGGGCAACTTCATGACATCTAGCATTGTCCAGAGTG
ATGATTCCTTAAGTTCAGTTATTAGTGGAAGTAACGGTTTGCATTCTGGA
TTAGGAGCATATCATCATCCATATGAAATCAAAACTAATTTGTCACAGAT
TATTAATTCTAGAAAATTGTTTCGACGAAGACAGCGTAATTACTCAGATG
GATCTGATATTGATGCTTCTCTTGTGTCCTACGAAGAACATCTAGCTGTT
TATTATTCTATGAAGGAAAATCAAAAGCCATCTAGTGCTACCCATCCTAC
TAATCTTGATCAAGAAATTGGACATTCTATCCTAGCACAAGTTCATCACG
AATTAGCACGATTGCACGAATCTGGACGATTTGTTAAATCAAAACGACTC
GCTCCTGGCTGTTTACATCATCAATTTTGGTCAAATCTTTTAAATGAAAA
TGATTCCCCTGAAGAATCAGAGCAAAAATCACCCACTAATCATGACTTGG
ATATCAATTGGGAATCTTGTTTATTTCATGAAAGACATGCAGCACAACTT
GGTTGTCTCGAAGCAGTTATTGTTATGGCACGGTATTGTTTAAATATGTC
AGGACATATGCTTCAGGATTGTCCTCTTCCTCCGAATCAGAATGATATAG
AATGTGGCCTTGATTATCTATGGAGAGCAGCTGACAGTGGCGATAGGAGA
TCTATGATTGAGTTAGCGAATTTATATCGGAAAACTGAATATTTCGGCGA
AATATTCAATGAAATTAACAAAACAACATTAGAAGTTAATTGGTTTGAAG
CAGTTAAATGGTATAAACGTGCTTTCGAAGCTGTCAATAAACTGGATGGG
CAAATCGATTCAAAAGACGCGGAAGGTAGATATGATTCGGCCGAAGATTT
AATGCCACCACAAGAAATTCTGGCATCGATGGCAGAGTTGTATTTAAAAG
GTGGTTACGGATTGGAAAAAAATTGTCAATTGGCTGGAGAACTATATAGT
CAGGCTGCAGAGATTGCCACAAATGCTCTTCAAGGACGTCAAGCTGTGAA
ATATTATGAGCTTGCCGACACTGCATATTCACAAGACGAAAATTGTGAAT
GAAAATCTTGCTGTTCATCTGTCAATATCATTTTTCTAAAAATGCTTTTC
GCTACTTACATTGATTTTTACATTAAACCAACTAACGCTAACATCTATTG
TTTTGTATATTGTAAATTGCATTAAGATTTTTTGTTTGGTTTTTATTTGG
AATAGACAAAATTGTTT
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protein sequence of SMED30013397-orf-1

>SMED30013397-orf-1 ID=SMED30013397-orf-1|Name=SMED30013397-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=784bp
MDEDIESCEDTNFSELLNSLECNTELDDFALYSVNSIKYRNQRRPHSLSI
SWNSPDSDRTDTISPALKRWFRAVSKICKHDDDIDPWHDFTIDTIKPDKA
IRYRYSAIKKKWVQDEIWVKLETLPFDHGAMRECFRLKKLSTTGINNNHD
WNFSSNYVAKQYINLVNRDVYFEDVKLQMESKLWAEEYNRQNPPKKIDIF
QLSIIELIDRENKPLYHIEHFMEGTYLKYNSNSGYVDDSCLRNTPQAFSH
FTFERSGHRIIIVDIQGVGDLYTDPQVHTADGLNYGDGNLGLRGMALFFS
SHRCNPICHYLGLSEFDMHQNELVDNDLDQEIADHDISTISIDALPEEDS
CAFSSKSYNEIKKRNRSISFKMSGTVIRDGRTSPCVTSPAFLDQLFPAPI
DLIRAMSVDSGVQSVSTPFVSQGNFMTSSIVQSDDSLSSVISGSNGLHSG
LGAYHHPYEIKTNLSQIINSRKLFRRRQRNYSDGSDIDASLVSYEEHLAV
YYSMKENQKPSSATHPTNLDQEIGHSILAQVHHELARLHESGRFVKSKRL
APGCLHHQFWSNLLNENDSPEESEQKSPTNHDLDINWESCLFHERHAAQL
GCLEAVIVMARYCLNMSGHMLQDCPLPPNQNDIECGLDYLWRAADSGDRR
SMIELANLYRKTEYFGEIFNEINKTTLEVNWFEAVKWYKRAFEAVNKLDG
QIDSKDAEGRYDSAEDLMPPQEILASMAELYLKGGYGLEKNCQLAGELYS
QAAEIATNALQGRQAVKYYELADTAYSQDENCE*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000034epidermis
PLANA:0000070intestinal phagocyte
PLANA:0003117parapharyngeal cell
Vocabulary: molecular function
TermDefinition
GO:0004674protein serine/threonine kinase activity
GO:0005515protein binding
GO:0005524ATP binding
GO:0003746translation elongation factor activity
GO:0004686elongation factor-2 kinase activity
GO:0005509calcium ion binding
GO:0005516calmodulin binding
GO:0016301kinase activity
Vocabulary: INTERPRO
TermDefinition
IPR004166MHCK_EF2_kinase
IPR011990TPR-like_helical_dom_sf
IPR011009Kinase-like_dom_sf
Vocabulary: biological process
TermDefinition
GO:0006468protein phosphorylation
GO:0006414translational elongation
GO:0016310phosphorylation
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR004166MHCK/EF2 kinaseSMARTSM00811alpha_kinasecoord: 109..308
e-value: 1.4E-96
score: 336.9
IPR004166MHCK/EF2 kinasePFAMPF02816Alpha_kinasecoord: 128..308
e-value: 6.4E-61
score: 205.7
IPR004166MHCK/EF2 kinasePROSITEPS51158ALPHA_KINASEcoord: 104..316
score: 43.265
NoneNo IPR availableGENE3DG3DSA:3.30.200.20coord: 147..223
e-value: 1.1E-22
score: 82.6
coord: 96..146
e-value: 4.0E-14
score: 54.7
NoneNo IPR availableGENE3DG3DSA:3.20.200.10coord: 224..336
e-value: 3.5E-34
score: 119.2
NoneNo IPR availablePANTHERPTHR45992FAMILY NOT NAMEDcoord: 97..770
NoneNo IPR availablePANTHERPTHR45992:SF3EUKARYOTIC ELONGATION FACTOR 2 KINASEcoord: 97..770
NoneNo IPR availableCDDcd16967Alpha_kinase_eEF2Kcoord: 100..308
e-value: 7.66017E-137
score: 401.324
NoneNo IPR availableSUPERFAMILYSSF81901HCP-likecoord: 586..763
IPR011990Tetratricopeptide-like helical domain superfamilyGENE3DG3DSA:1.25.40.10coord: 523..782
e-value: 7.3E-13
score: 50.2
IPR011009Protein kinase-like domain superfamilySUPERFAMILYSSF56112Protein kinase-like (PK-like)coord: 90..319