THUMP domain-containing protein 1

Overview
NameTHUMP domain-containing protein 1
Smed IDSMED30013367
Length (bp)884
Neoblast Clusters

Zeng et. al., 2018



▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)



Explore this single cell expression dataset with our NB Cluster Shiny App



 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of THUMP domain-containing protein 1 (SMED30013367) t-SNE clustered cells

Violin plots show distribution of expression levels for THUMP domain-containing protein 1 (SMED30013367) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of THUMP domain-containing protein 1 (SMED30013367) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for THUMP domain-containing protein 1 (SMED30013367) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020



SMED30013367

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 1

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
X1 cellSMED30013367SMESG000006826.1 SmedASXL_008975SmedAsxl_ww_GCZZ01PMID:26114597
Zhu et al., 2015		FACS sorted cell population asexual adult RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
[Close]
BLAST of THUMP domain-containing protein 1 vs. Ensembl Human
Match: THUMPD1 (THUMP domain containing 1 [Source:HGNC Symbol;Acc:HGNC:23807])

HSP 1 Score: 62.003 bits (149), Expect = 2.585e-10
Identity = 61/251 (24.30%), Postives = 114/251 (45.42%), Query Frame = 1 
Query:  115 KLKPSTRGFFITCNGFEKEAVIESYKMLNE---------AVVRLDKTNSQVELKDNESIIPINKXXXXXXXXXXXILSALKKEKICESKQLFQQMSIGIKNCIFINNKSSYSTNELVNSVFACIKTSELPPAKYISRLLPVSTTCDSNIENIKLNFNSSWEVFVKNRNPANVVKKYHVDFKARHFDKINKMDVIKIVQDTLKDTCSEYEGTLNDYMPGIVIIYFNVLCKVTCISFLEDYQSNFKYNVQQFL 840
            +L+P  +G  ITCN  E++ V E+Y +LNE              D+  S  E +D+++   + KE  D   S    L            + FQ +  G  N +FI         +LV+ +   +  ++    + I R+LP+S TC + +E++K    +  E + K  N       + + +K+R+   +N+ +VI+ +   +    SE +  L +    +V+     +C   C+S ++DY    KYN+Q+ +
Sbjct:   38 QLEPGLQGILITCNMNERKCVEEAYSLLNEYGDDMYGPEKFTDKDQQPSGSEGEDDDAEAALKKEVGDIKASTEMRL------------RRFQSVESGANNVVFIRT-LGIEPEKLVHHILQDMYKTKKKKTRVILRMLPISGTCKAFLEDMKKYAETFLEPWFKAPNKGT----FQIVYKSRNNSHVNREEVIRELAGIVCTLNSENKVDLTNPQYTVVVEIIKAVC---CLSVVKDYMLFRKYNLQEVV 268
[Close]
BLAST of THUMP domain-containing protein 1 vs. Ensembl Human
Match: THUMPD1 (THUMP domain containing 1 [Source:HGNC Symbol;Acc:HGNC:23807])

HSP 1 Score: 62.003 bits (149), Expect = 2.585e-10
Identity = 61/251 (24.30%), Postives = 114/251 (45.42%), Query Frame = 1 
Query:  115 KLKPSTRGFFITCNGFEKEAVIESYKMLNE---------AVVRLDKTNSQVELKDNESIIPINKXXXXXXXXXXXILSALKKEKICESKQLFQQMSIGIKNCIFINNKSSYSTNELVNSVFACIKTSELPPAKYISRLLPVSTTCDSNIENIKLNFNSSWEVFVKNRNPANVVKKYHVDFKARHFDKINKMDVIKIVQDTLKDTCSEYEGTLNDYMPGIVIIYFNVLCKVTCISFLEDYQSNFKYNVQQFL 840
            +L+P  +G  ITCN  E++ V E+Y +LNE              D+  S  E +D+++   + KE  D   S    L            + FQ +  G  N +FI         +LV+ +   +  ++    + I R+LP+S TC + +E++K    +  E + K  N       + + +K+R+   +N+ +VI+ +   +    SE +  L +    +V+     +C   C+S ++DY    KYN+Q+ +
Sbjct:   38 QLEPGLQGILITCNMNERKCVEEAYSLLNEYGDDMYGPEKFTDKDQQPSGSEGEDDDAEAALKKEVGDIKASTEMRL------------RRFQSVESGANNVVFIRT-LGIEPEKLVHHILQDMYKTKKKKTRVILRMLPISGTCKAFLEDMKKYAETFLEPWFKAPNKGT----FQIVYKSRNNSHVNREEVIRELAGIVCTLNSENKVDLTNPQYTVVVEIIKAVC---CLSVVKDYMLFRKYNLQEVV 268
[Close]
BLAST of THUMP domain-containing protein 1 vs. Ensembl Human
Match: THUMPD1 (THUMP domain containing 1 [Source:HGNC Symbol;Acc:HGNC:23807])

HSP 1 Score: 62.003 bits (149), Expect = 2.585e-10
Identity = 61/251 (24.30%), Postives = 114/251 (45.42%), Query Frame = 1 
Query:  115 KLKPSTRGFFITCNGFEKEAVIESYKMLNE---------AVVRLDKTNSQVELKDNESIIPINKXXXXXXXXXXXILSALKKEKICESKQLFQQMSIGIKNCIFINNKSSYSTNELVNSVFACIKTSELPPAKYISRLLPVSTTCDSNIENIKLNFNSSWEVFVKNRNPANVVKKYHVDFKARHFDKINKMDVIKIVQDTLKDTCSEYEGTLNDYMPGIVIIYFNVLCKVTCISFLEDYQSNFKYNVQQFL 840
            +L+P  +G  ITCN  E++ V E+Y +LNE              D+  S  E +D+++   + KE  D   S    L            + FQ +  G  N +FI         +LV+ +   +  ++    + I R+LP+S TC + +E++K    +  E + K  N       + + +K+R+   +N+ +VI+ +   +    SE +  L +    +V+     +C   C+S ++DY    KYN+Q+ +
Sbjct:   38 QLEPGLQGILITCNMNERKCVEEAYSLLNEYGDDMYGPEKFTDKDQQPSGSEGEDDDAEAALKKEVGDIKASTEMRL------------RRFQSVESGANNVVFIRT-LGIEPEKLVHHILQDMYKTKKKKTRVILRMLPISGTCKAFLEDMKKYAETFLEPWFKAPNKGT----FQIVYKSRNNSHVNREEVIRELAGIVCTLNSENKVDLTNPQYTVVVEIIKAVC---CLSVVKDYMLFRKYNLQEVV 268
[Close]
BLAST of THUMP domain-containing protein 1 vs. Ensembl Celegans
Match: W02G9.3 (pep chromosome:WBcel235:V:2672986:2674026:1 gene:WBGene00020953.1 transcript:W02G9.3.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:W02G9.3)

HSP 1 Score: 50.0618 bits (118), Expect = 5.315e-7
Identity = 54/208 (25.96%), Postives = 98/208 (47.12%), Query Frame = 1 
Query:  136 GFFITCNGFEKEAVIESYKMLNEAVVRLDKTNSQVELKDNESI-----IPINKXXXXXXXXXXXILSALKKEKICESKQLFQ------------QMSIGIKNCIFINNKSSYSTNELVNSVFACIKTSELPPAKYISRLLPVSTTCDSNIENIKLNFNSSWEVFVK------NRNPANVVKKYHVDFKARHFDKINKMDVIKIVQDTL 690
            G F +C G EK+A+ E+Y +++E    L+   + + LK  E+       P N    + ++SD DI  ALK  K C+ ++  +            Q   G+KNCIF++ K++ +   L   +     T + P  +++ R+ PV  T       + ++ +   EV +K        +    +  Y V+FKAR+ D + K  V+++V D +
Sbjct:   28 GLFFSCEGHEKQALQEAYSIIDEL---LEDPANGISLKAPEAAPQGSEAPGNP--AEAEDSDEDIADALK--KACDDQRQPKPGNFVKKERRCIQRPTGVKNCIFVSVKNA-NIQLLAEKMVEL--TQKAPRCRFLQRVYPVEHT-------LAVDLSKMNEVLMKVISDTLKADGTGKLPTYSVEFKARNNDSVAKNSVLQMVDDAV 218
[Close]
BLAST of THUMP domain-containing protein 1 vs. Ensembl Fly
Match: CG15014 (gene:FBgn0035532 transcript:FBtr0073340)

HSP 1 Score: 47.3654 bits (111), Expect = 7.956e-6
Identity = 49/198 (24.75%), Postives = 85/198 (42.93%), Query Frame = 1 
Query:  118 LKPSTRGFFITCNGFEKEAVIESYKMLNEAVVRL---DKTNSQVELKDNESIIPINKXXXXXXXXXXXILSALK---------KEKICESKQLFQQMSIGIKNCIFINNKSSYSTNELVNSVFACIKTSELPPAKYISRLLPVSTTCDSNIENIKLNFNSSWEVFVKN--RNPANVVKKYHVDFKARHFDKINKMDVI 669
            L+P  RGFF TCN  EK  V E Y +LN     L   +K  ++ E K  E     +  E+D   +                  +E + + K  FQ +     NC+FI  +       L   +   I T+    ++++ RL+P+   C +N+ +I     ++ E+F K+  + P +    Y + F  R+  +I +  +I
Sbjct:   31 LQPGQRGFFATCNINEKACVRECYNLLNHYADILYGSEKPENEPEKKQPEEGAGGDAGEDDPKPAAGGTSDDDDDLEAAAAKCREMLSQRKMRFQNVDTNTTNCVFIRTQLEDPV-ALGKHIINDIATTGKSMSRFVLRLVPIEVVCRANMPDI---ITAAGELFDKHFLKEPTS----YGIIFNHRYNQQIKRDQII 220
[Close]
BLAST of THUMP domain-containing protein 1 vs. Ensembl Xenopus
Match: thumpd1 (THUMP domain containing 1 [Source:NCBI gene;Acc:394656])

HSP 1 Score: 63.929 bits (154), Expect = 3.169e-11
Identity = 69/255 (27.06%), Postives = 123/255 (48.24%), Query Frame = 1 
Query:   94 KKGKYECKLKPSTRGFFITCNGFEKEAVIESYKMLNEAVVRLDKTNSQVELKDNESIIPINKXXXXXXXXXXXILSALKKE----KICESKQL--FQQMSIGIKNCIFINNKSSYSTNELVNSVFACIKTSELPPAKYISRLLPVSTTCDSNIENIKLNFNSSWEVFVKNRNPANVVKKYHVDFKARHFDKINKMDVIKIVQDTLKDTCSEYEGTLNDYMPGIVIIYFNVLCKVTCISFLEDYQSNFKYNVQQFL 840
            K+ K   +L+   +G  ITCN  E++ V E+Y +LNE   ++       E  D            + +E D D  +ALKKE    +    K L  FQ +  G  N IFI    +    +LV+ +   + T++    + I R+LPVS TC + +E++K    + +  + K+ N  +    + + +KAR+ + +N+ +VIK +   +     E +  L++  P   +I   ++  V C S ++DY    KYN+Q+ +
Sbjct:   21 KRQKRRHELEVGMQGILITCNMNERKCVAEAYSLLNEYGDQMYGPEKLSEKDDG---------LSESEEEDDDAEAALKKEVDQIRTSTEKNLRRFQSVESGANNVIFIRT-LNVEPEKLVHHILKDVHTTKKKKTRVILRMLPVSGTCKAFLEDLKKYAETFFAPWFKSPNKGS----FQIAYKARNNNHMNRDEVIKELAGIVASQNPENKVDLSN--PEYTVI-VEIIKNVCCFSVVKDYTVFRKYNLQEVI 258
[Close]
BLAST of THUMP domain-containing protein 1 vs. Ensembl Xenopus
Match: thumpd1 (THUMP domain containing 1 [Source:NCBI gene;Acc:394656])

HSP 1 Score: 53.5286 bits (127), Expect = 1.026e-7
Identity = 42/160 (26.25%), Postives = 82/160 (51.25%), Query Frame = 1 
Query:  361 FQQMSIGIKNCIFINNKSSYSTNELVNSVFACIKTSELPPAKYISRLLPVSTTCDSNIENIKLNFNSSWEVFVKNRNPANVVKKYHVDFKARHFDKINKMDVIKIVQDTLKDTCSEYEGTLNDYMPGIVIIYFNVLCKVTCISFLEDYQSNFKYNVQQFL 840
            FQ +  G  N IFI    +    +LV+ +   + T++    + I R+LPVS TC + +E++K    + +  + K+ N  +    + + +KAR+ + +N+ +VIK +   +     E +  L++  P   +I   ++  V C S ++DY    KYN+Q+ +
Sbjct:  100 FQSVESGANNVIFIRT-LNVEPEKLVHHILKDVHTTKKKKTRVILRMLPVSGTCKAFLEDLKKYAETFFAPWFKSPNKGS----FQIAYKARNNNHMNRDEVIKELAGIVASQNPENKVDLSN--PEYTVI-VEIIKNVCCFSVVKDYTVFRKYNLQEVI 251
[Close]
BLAST of THUMP domain-containing protein 1 vs. Ensembl Mouse
Match: Thumpd1 (THUMP domain containing 1 [Source:MGI Symbol;Acc:MGI:2444479])

HSP 1 Score: 65.0846 bits (157), Expect = 1.367e-11
Identity = 65/248 (26.21%), Postives = 118/248 (47.58%), Query Frame = 1 
Query:  115 KLKPSTRGFFITCNGFEKEAVIESYKMLNEAVVRLDKTNSQVELKDNESIIPINKXXXXXXXXXXXILSALKKE----KICESKQL--FQQMSIGIKNCIFINNKSSYSTNELVNSVFACIKTSELPPAKYISRLLPVSTTCDSNIENIKLNFNSSWEVFVKNRNPANVVKKYHVDFKARHFDKINKMDVIKIVQDTLKDTCSEYEGTLNDYMPGIVIIYFNVLCKVTCISFLEDYQSNFKYNVQQFL 840
            +L+P  +G  ITCN  E++ V E+Y +LNE            ++   E  I  +++    +  D D  +ALKKE    K    K+L  FQ +  G  N +FI         +LV+ +   +  ++    + I R+LP+S TC + +E++K    +  E + K  N       + + +K+R+   +N+ +VIK +   +    SE +  L +    +V+     +C   C+S ++DY    KYN+Q+ +
Sbjct:   38 QLEPGLQGILITCNMNERKCVEEAYSLLNEY---------GDDMYGPEKFIDKDQQPSGSEGEDDDAEAALKKEVGDIKASTEKRLRRFQSVESGANNVVFIRT-LGIEPEKLVHHILQDMYKTKKKKTRVILRMLPISGTCKAFLEDMKKYAETFLEPWFKAPNKGT----FQIVYKSRNNSHMNREEVIKELAGIVGSLNSENKVDLTNPEYTVVVEIIKAVC---CLSVVKDYVLFRKYNLQEVV 268
[Close]
BLAST of THUMP domain-containing protein 1 vs. UniProt/SwissProt
Match: sp|Q24K03|THUM1_BOVIN (THUMP domain-containing protein 1 OS=Bos taurus OX=9913 GN=THUMPD1 PE=2 SV=1)

HSP 1 Score: 67.0106 bits (162), Expect = 2.549e-11
Identity = 66/262 (25.19%), Postives = 119/262 (45.42%), Query Frame = 1 
Query:  100 GKYECKLKPSTRGFFITCNGFEKEAVIESYKMLN---------EAVVRLDKTNSQVELKDNESIIPINKXXXXXXXXXXXILSALKKE--KICESKQL----FQQMSIGIKNCIFINNKSSYSTNELVNSVFACIKTSELPPAKYISRLLPVSTTCDSNIENIKLNFNSSWEVFVKNRNPANVVKKYHVDFKARHFDKINKMDVIKIVQDTLKDTCSEYEGTLNDYMPGIVIIYFNVLCKVTCISFLEDYQSNFKYNVQQFL 840
            G    +L+P  +G  ITCN  E++ V E+Y +LN         E     D+  S  E +D++                  + +ALKKE   I  S ++    FQ +  G  N +FI         +LV+ +   I  ++    + I R+LP+S TC + +E++K    +  E + K  N       + + +K+R+   +N+ +VIK +   +    SE +  L++    +V+     +C   C+S ++DY    KYN+Q+ +
Sbjct:   33 GGGPRQLEPGIQGILITCNMNERKCVEEAYSLLNEYGDDMYGPEKFADKDQQPSGSEGEDDD------------------VEAALKKEVGDIKASTEMRLRRFQSVESGANNVVFIRT-LGIEPEKLVHHILQDIYKTKKKKTRVILRMLPISGTCKAFLEDMKKYAETFLEPWFKAPNKGT----FQIVYKSRNNSHMNREEVIKELAGIVGSLNSENKVDLSNPQYTVVVEIIKAVC---CLSVVKDYMLFRKYNLQEVV 268
[Close]
BLAST of THUMP domain-containing protein 1 vs. UniProt/SwissProt
Match: sp|Q99J36|THUM1_MOUSE (THUMP domain-containing protein 1 OS=Mus musculus OX=10090 GN=Thumpd1 PE=1 SV=1)

HSP 1 Score: 65.0846 bits (157), Expect = 9.565e-11
Identity = 65/248 (26.21%), Postives = 118/248 (47.58%), Query Frame = 1 
Query:  115 KLKPSTRGFFITCNGFEKEAVIESYKMLNEAVVRLDKTNSQVELKDNESIIPINKXXXXXXXXXXXILSALKKE----KICESKQL--FQQMSIGIKNCIFINNKSSYSTNELVNSVFACIKTSELPPAKYISRLLPVSTTCDSNIENIKLNFNSSWEVFVKNRNPANVVKKYHVDFKARHFDKINKMDVIKIVQDTLKDTCSEYEGTLNDYMPGIVIIYFNVLCKVTCISFLEDYQSNFKYNVQQFL 840
            +L+P  +G  ITCN  E++ V E+Y +LNE            ++   E  I  +++    +  D D  +ALKKE    K    K+L  FQ +  G  N +FI         +LV+ +   +  ++    + I R+LP+S TC + +E++K    +  E + K  N       + + +K+R+   +N+ +VIK +   +    SE +  L +    +V+     +C   C+S ++DY    KYN+Q+ +
Sbjct:   38 QLEPGLQGILITCNMNERKCVEEAYSLLNEY---------GDDMYGPEKFIDKDQQPSGSEGEDDDAEAALKKEVGDIKASTEKRLRRFQSVESGANNVVFIRT-LGIEPEKLVHHILQDMYKTKKKKTRVILRMLPISGTCKAFLEDMKKYAETFLEPWFKAPNKGT----FQIVYKSRNNSHMNREEVIKELAGIVGSLNSENKVDLTNPEYTVVVEIIKAVC---CLSVVKDYVLFRKYNLQEVV 268
[Close]
BLAST of THUMP domain-containing protein 1 vs. UniProt/SwissProt
Match: sp|Q9NXG2|THUM1_HUMAN (THUMP domain-containing protein 1 OS=Homo sapiens OX=9606 GN=THUMPD1 PE=1 SV=2)

HSP 1 Score: 62.003 bits (149), Expect = 1.242e-9
Identity = 61/251 (24.30%), Postives = 114/251 (45.42%), Query Frame = 1 
Query:  115 KLKPSTRGFFITCNGFEKEAVIESYKMLNE---------AVVRLDKTNSQVELKDNESIIPINKXXXXXXXXXXXILSALKKEKICESKQLFQQMSIGIKNCIFINNKSSYSTNELVNSVFACIKTSELPPAKYISRLLPVSTTCDSNIENIKLNFNSSWEVFVKNRNPANVVKKYHVDFKARHFDKINKMDVIKIVQDTLKDTCSEYEGTLNDYMPGIVIIYFNVLCKVTCISFLEDYQSNFKYNVQQFL 840
            +L+P  +G  ITCN  E++ V E+Y +LNE              D+  S  E +D+++   + KE  D   S    L            + FQ +  G  N +FI         +LV+ +   +  ++    + I R+LP+S TC + +E++K    +  E + K  N       + + +K+R+   +N+ +VI+ +   +    SE +  L +    +V+     +C   C+S ++DY    KYN+Q+ +
Sbjct:   38 QLEPGLQGILITCNMNERKCVEEAYSLLNEYGDDMYGPEKFTDKDQQPSGSEGEDDDAEAALKKEVGDIKASTEMRL------------RRFQSVESGANNVVFIRT-LGIEPEKLVHHILQDMYKTKKKKTRVILRMLPISGTCKAFLEDMKKYAETFLEPWFKAPNKGT----FQIVYKSRNNSHVNREEVIRELAGIVCTLNSENKVDLTNPQYTVVVEIIKAVC---CLSVVKDYMLFRKYNLQEVV 268
[Close]
BLAST of THUMP domain-containing protein 1 vs. TrEMBL
Match: A0A564YGX8 (Uncharacterized protein OS=Hymenolepis diminuta OX=6216 GN=WMSIL1_LOCUS6151 PE=4 SV=1)

HSP 1 Score: 99.7525 bits (247), Expect = 1.645e-20
Identity = 81/273 (29.67%), Postives = 132/273 (48.35%), Query Frame = 1 
Query:  115 KLKPSTRGFFITCNGFE-KEAVIESYKMLNEAVVRLDKTNSQVELKDNESIIPINKXXXXXXXXXXXILSALKKEKICESKQ---LFQQMSIGIKNCIFINNKSS-YSTNELVNSVFACIKTSELPPAKYISRLLPVSTTCDSNIENI----KLNFNSSWEV------------------------FVKNRNPANVVKKYHVDFKARHFDKINKMDVIKIVQDTLKDTCSEYEGTLNDYMPGIVIIYFNVLCKVTCISFLEDYQSNFKYNVQQ 834
            +L+P   GF  T N  +  +A IE Y++LNEA  RL   N   E  + E +   +K++ DE + D D  SALK+E   +SK    +F  +  G+ NC F+ N+S   S+ ++VNS+F   +       + + R LPV  TC  +I ++    +  F + W+                         F++  +  +  + + V+FK R++DKI K DV+  V  T ++   E+    +      +I+  NVLC V C+SFLE Y    KYN+ +
Sbjct:   42 RLEPGMTGFLFTSNNKDIHQAQIEVYRLLNEANARL---NGSKEEGEKEKVA--DKQKSDEVDDDMDFTSALKEELKSDSKSSRYIFNGVKTGVSNCGFVLNQSECNSSADIVNSIFQYTQKKGEADTRRVLRFLPVVGTCRPDISDLSALLRRAFRAYWDSSIEGFEDGEPLCLICPKVPLQRARFIEKPDSEDAKRYFTVNFKTRNYDKIKKEDVVMTVIATFQEIAPEWSPITHG---ADLIVSVNVLCNVLCLSFLEKYNDFAKYNIHE 306
[Close]
BLAST of THUMP domain-containing protein 1 vs. TrEMBL
Match: A0A158REQ6 (Uncharacterized protein OS=Hydatigena taeniaeformis OX=6205 GN=TTAC_LOCUS7816 PE=4 SV=1)

HSP 1 Score: 100.908 bits (250), Expect = 5.425e-20
Identity = 71/276 (25.72%), Postives = 132/276 (47.83%), Query Frame = 1 
Query:  115 KLKPSTRGFFITC-NGFEKEAVIESYKMLNEAVVRLDKT----NSQVELKDNESIIPINKXXXXXXXXXXXILSALKKEKICES---KQLFQQMSIGIKNCIFINNKSSYSTN-ELVNSVFACIKTSELPPAKYISRLLPVSTTCDSNIENIKLNFNSSWEV---------------------------FVKNRNPANVVKKYHVDFKARHFDKINKMDVIKIVQDTLKDTCSEYEGTLNDYMPGIVIIYFNVLCKVTCISFLEDYQSNFKYNVQQ 834
            +L+P   G  +TC N  E++A+IE+Y++LNEA  RL+ T    +  V + DNE +                I SAL KE   +S   +  F  +  G+ NC F+ N+S+ S++ +LV  VF  +  S    ++++ R  PV  TC  + +++++    +W++                           FVK  +  +  K + V+F+AR++ K++K + +  V D +++   ++           ++I  +VL  V C+ FLE + +  KYN+ +
Sbjct:  447 RLEPGMTGILLTCVNKAERQALIEAYRLLNEAHERLNGTRRSEDKAVAVSDNEDL---------------SIASALIKEMKSDSTSSQYTFYGVKTGVSNCTFVLNQSADSSSADLVYEVFRHVMASREANSRHVYRFQPVLATCRPDRDDLRILMRKAWKIFWNSEDTFEDGRPLCLLCSKVPFQRARFVKKDDSGDTKKHFMVNFRARNYGKMSKAEALMAVIDIMREVAPDWSPVCAG---ADLVISIDVLRTVLCLGFLEKFSTFSKYNISE 704
[Close]
BLAST of THUMP domain-containing protein 1 vs. TrEMBL
Match: A0A068XZJ0 (THUMP domain containing protein 1 OS=Echinococcus multilocularis OX=6211 GN=EmuJ_000490700 PE=4 SV=1)

HSP 1 Score: 96.6709 bits (239), Expect = 1.691e-19
Identity = 74/277 (26.71%), Postives = 137/277 (49.46%), Query Frame = 1 
Query:  103 KYECKLKPSTRGFFITCNG-FEKEAVIESYKMLNEAVVRLDKTNSQVELKDNESIIPINKXXXXXXXXXXXILSALKKEKICES---KQLFQQMSIGIKNCIFINNKS-SYSTNELVNSVFACIKTSELPPAKYISRLLPVSTTCDSNIENIKLNFNSSWEVF---------------------------VKNRNPANVVKKYHVDFKARHFDKINKMDVIKIVQDTLKDTCSEYEGTLNDYMPGIVIIYFNVLCKVTCISFLEDYQSNFKYNVQQF 837
            ++  +L+P   G  +T N   E++A++E+Y++LNEA  RL+ T+    L D+       KE+   D+ D DI SAL +E   +S   + +F+ +  G+ NC F+ N+S   S+ +LV  VF  +  S    ++ + R  PV  TC    E++++  + +W+ F                           VK  +   V K + V+F+AR++ K++K + + +V   +++   ++           ++I  +VLC V C+SFLE +    KYN+++ 
Sbjct:   39 RFPRRLEPGMTGILLTSNNKEERQALMEAYRLLNEAHKRLNGTH----LSDD-------KEDSVSDKEDLDIASALIEEMKSDSTTSQYIFRAVKTGVSNCAFVVNQSEDRSSADLVYEVFRQVMASREANSRRVLRFQPVLATCRPGKEDLRVLMSKAWKAFWNGVDGYEDGRPLCLLCSKVPLQRARFVKRDDSGEVKKYFMVNFRARNYGKMSKEEAVMVVIAVMQEIAPDWSPV---RAGADLVISVDVLCTVLCLSFLEKFSDFAKYNIREL 301
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BLAST of THUMP domain-containing protein 1 vs. TrEMBL
Match: A0A0R3S9I8 (Uncharacterized protein OS=Hymenolepis diminuta OX=6216 GN=HDID_LOCUS921 PE=4 SV=1)

HSP 1 Score: 98.9821 bits (245), Expect = 2.231e-19
Identity = 81/273 (29.67%), Postives = 132/273 (48.35%), Query Frame = 1 
Query:  115 KLKPSTRGFFITCNGFE-KEAVIESYKMLNEAVVRLDKTNSQVELKDNESIIPINKXXXXXXXXXXXILSALKKEKICESKQ---LFQQMSIGIKNCIFINNKSS-YSTNELVNSVFACIKTSELPPAKYISRLLPVSTTCDSNIENI----KLNFNSSWEV------------------------FVKNRNPANVVKKYHVDFKARHFDKINKMDVIKIVQDTLKDTCSEYEGTLNDYMPGIVIIYFNVLCKVTCISFLEDYQSNFKYNVQQ 834
            +L+P   GF  T N  +  +A IE Y++LNEA  RL   N   E  + E +   +K++ DE + D D  SALK+E   +SK    +F  +  G+ NC F+ N+S   S+ ++VNS+F   +       + + R LPV  TC  +I ++    +  F + W+                         F++  +  +  + + V+FK R++DKI K DV+  V  T ++   E+    +      +I+  NVLC V C+SFLE Y    KYN+ +
Sbjct:  464 RLEPGMTGFLFTSNNKDIHQAQIEVYRLLNEANARL---NGSKEEGEKEKVA--DKQKSDEVDDDMDFTSALKEELKSDSKSSRYIFNGVKTGVSNCGFVLNQSECNSSADIVNSIFQYTQKKGEADTRRVLRFLPVVGTCRPDISDLSALLRRAFRAYWDSSIEGFEDGEPLCLICPKVPLQRARFIEKPDSEDAKRYFTVNFKTRNYDKIKKEDVVMTVIATFQEIAPEWSPITHG---ADLIVSVNVLCNVLCLSFLEKYNDFAKYNIHE 728
[Close]
BLAST of THUMP domain-containing protein 1 vs. TrEMBL
Match: W6UTU9 (Porphobilinogen deaminase OS=Echinococcus granulosus OX=6210 GN=EGR_01214 PE=4 SV=1)

HSP 1 Score: 96.6709 bits (239), Expect = 1.236e-18
Identity = 74/278 (26.62%), Postives = 138/278 (49.64%), Query Frame = 1 
Query:  100 GKYECKLKPSTRGFFITCNG-FEKEAVIESYKMLNEAVVRLDKTNSQVELKDNESIIPINKXXXXXXXXXXXILSALKKEKICES---KQLFQQMSIGIKNCIFINNKSS-YSTNELVNSVFACIKTSELPPAKYISRLLPVSTTCDSNIENIKLNFNSSWEV---------------------------FVKNRNPANVVKKYHVDFKARHFDKINKMDVIKIVQDTLKDTCSEYEGTLNDYMPGIVIIYFNVLCKVTCISFLEDYQSNFKYNVQQF 837
             ++  +L+P   G  +T N   E++A++E+Y++LNEA  RL+ T+    L D+       KE+   D+ D DI SAL +E   +S   + +F+ +  G+ NC F+ N+S+  S+ +LV  VF  +  S    ++ + R  PV  TC    E++++  + +W+                            FVK  +   V K + V+F+AR++ K++K + + +V   +++   ++    +      ++I  +VLC V C+SFLE +    KYN+ + 
Sbjct:  450 ARFPRRLEPGMTGILLTSNNKEERQALMEAYRLLNEAHKRLNGTH----LSDD-------KEDSVSDKEDVDIASALIEEMKSDSTTSQYIFRAVKTGVSNCAFVVNQSADRSSADLVYEVFRHVMASREANSRRVLRFQPVLATCRPGKEDLRVLMSKAWKAFWNGVDGYADGRPLCLLCSKVPLQRARFVKRDDSGEVKKYFMVNFRARNYGKMSKEEAVMVVIAVMQEIAPDWSPVRSG---ADLVISVDVLCTVLCLSFLEKFSDFAKYNISEL 713
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BLAST of THUMP domain-containing protein 1 vs. Ensembl Cavefish
Match: thumpd1 (THUMP domain containing 1 [Source:NCBI gene;Acc:103030207])

HSP 1 Score: 72.0182 bits (175), Expect = 6.514e-14
Identity = 74/259 (28.57%), Postives = 123/259 (47.49%), Query Frame = 1 
Query:   76 TKSKYFKKGKYECKLKPSTRGFFITCNGFEKEAVIESYKMLNEAVVRLDKTNSQVELKDNESIIPINKXXXXXXXXXXXILSALKKEKIC------ESKQLFQQMSIGIKNCIFINNKSSYSTNELVNSVFACIKTSELPPAKYISRLLPVSTTCDSNIENIKLNFNSSWEVFVKNRNPANVVKKYHVDFKARHFDKINKMDVIKIVQDTLKDTCSEYEGTLNDYMPGIVIIYFNVLCKVTCISFLEDYQSNFKYNVQQ 834
             +++  K+ + E  L    +G  ITCN   +    E+Y +L E   RL       EL D +S         DE++ + D+ +ALKKE +       + K+ FQ +  G  N +FI         +LV+ +   I  ++   ++ I R+LPVS TC +  E+++   +S  E + K  N A+    Y ++FKAR+     + DVIK +   +     E +  L D  P + II   ++  V C+S + DY    KYN+Q+
Sbjct:   62 AQARGGKRARRERALCTGMQGVLITCNMNAQRCTAEAYSLLGEYGDRLYGPE---ELGDPQS------SNSDEEQDEDDVEAALKKEVMQLQGSNKKRKRRFQAVDSGANNVVFIQT-HHVDPEKLVHHILQDIYQTKKKKSRVILRMLPVSGTCRAFPEDMEKYLSSYLEPWFKAPNHAS----YQINFKARNSSHNKRDDVIKALAGLVAKLNPENKVDLTD--PELTII-VEIIKSVCCVSVVRDYTLFRKYNLQE 303
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BLAST of THUMP domain-containing protein 1 vs. Ensembl Cavefish
Match: thumpd1 (THUMP domain containing 1 [Source:NCBI gene;Acc:103030207])

HSP 1 Score: 71.2478 bits (173), Expect = 9.127e-14
Identity = 74/259 (28.57%), Postives = 123/259 (47.49%), Query Frame = 1 
Query:   76 TKSKYFKKGKYECKLKPSTRGFFITCNGFEKEAVIESYKMLNEAVVRLDKTNSQVELKDNESIIPINKXXXXXXXXXXXILSALKKEKIC------ESKQLFQQMSIGIKNCIFINNKSSYSTNELVNSVFACIKTSELPPAKYISRLLPVSTTCDSNIENIKLNFNSSWEVFVKNRNPANVVKKYHVDFKARHFDKINKMDVIKIVQDTLKDTCSEYEGTLNDYMPGIVIIYFNVLCKVTCISFLEDYQSNFKYNVQQ 834
             +++  K+ + E  L    +G  ITCN   +    E+Y +L E   RL       EL D +S         DE++ + D+ +ALKKE +       + K+ FQ +  G  N +FI         +LV+ +   I  ++   ++ I R+LPVS TC +  E+++   +S  E + K  N A+    Y ++FKAR+     + DVIK +   +     E +  L D  P + II   ++  V C+S + DY    KYN+Q+
Sbjct:   12 AQARGGKRARRERALCTGMQGVLITCNMNAQRCTAEAYSLLGEYGDRL---YGPEELGDPQS------SNSDEEQDEDDVEAALKKEVMQLQGSNKKRKRRFQAVDSGANNVVFIQT-HHVDPEKLVHHILQDIYQTKKKKSRVILRMLPVSGTCRAFPEDMEKYLSSYLEPWFKAPNHAS----YQINFKARNSSHNKRDDVIKALAGLVAKLNPENKVDLTD--PELTII-VEIIKSVCCVSVVRDYTLFRKYNLQE 253
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BLAST of THUMP domain-containing protein 1 vs. Ensembl Sea Lamprey
Match: thumpd1 (THUMP domain containing 1 [Source:ZFIN;Acc:ZDB-GENE-040426-1805])

HSP 1 Score: 48.1358 bits (113), Expect = 5.524e-7
Identity = 36/171 (21.05%), Postives = 78/171 (45.61%), Query Frame = 1 
Query:  331 KEKICESKQLFQQMSIGIKNCIFINNKSSYSTNELVNSVFACIKTSELPPAKYISRLLPVSTTC---DSNIENIKLNFNSSWEVFVKNRNPANVVKKYHVDFKARHFDKINKMDVIKIVQDTLKDTCSEYEGTLNDYMPGIVIIYFNVLCKVTCISFLEDYQSNFKYNVQQ 834
            K++   +++ F+ ++ G  N +FI +      + LV+ + + +       ++++ R+LPV+ +C    +++E         W  F   R        + V +KAR+   +++ + IK V   +    +E    L +    +V+     +C   C+S + DY    KYN+Q+
Sbjct:   25 KKRGAAAQRRFRAVTSGANNVVFIRS-VGVEPDTLVHGILSELAELRQSKSRHVLRVLPVTASCRAYPADVERAAEAHLPRW--FAAPRR-----ATFQVVYKARNNGNMHREETIKAVAGVVLKLNAENHVDLTEPELTVVVEVIRAVC---CLSVVRDYVRLRKYNLQE 184
[Close]
BLAST of THUMP domain-containing protein 1 vs. Ensembl Sea Lamprey
Match: thumpd1 (THUMP domain containing 1 [Source:ZFIN;Acc:ZDB-GENE-040426-1805])

HSP 1 Score: 46.9802 bits (110), Expect = 1.907e-6
Identity = 36/172 (20.93%), Postives = 78/172 (45.35%), Query Frame = 1 
Query:  331 KEKICESKQLFQQMSIGIKNCIFINNKSSYSTNELVNSVFACIKTSELPPAKYISRLLPVSTTC---DSNIENIKLNFNSSWEVFVKNRNPANVVKKYHVDFKARHFDKINKMDVIKIVQDTLKDTCSEYEGTLNDYMPGIVIIYFNVLCKVTCISFLEDYQSNFKYNVQQF 837
            K++   +++ F+ ++ G  N +FI +      + LV+ + + +       ++++ R+LPV+ +C    +++E         W  F   R        + V +KAR+   +++ + IK V   +    +E    L +    +V+     +C   C+S + DY    KYN+Q+ 
Sbjct:   17 KKRGAAAQRRFRAVTSGANNVVFIRS-VGVEPDTLVHGILSELAELRQSKSRHVLRVLPVTASCRAYPADVERAAEAHLPRW--FAAPRR-----ATFQVVYKARNNGNMHREETIKAVAGVVLKLNAENHVDLTEPELTVVVEVIRAVC---CLSVVRDYVRLRKYNLQEV 177
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BLAST of THUMP domain-containing protein 1 vs. Ensembl Medaka
Match: thumpd1 (THUMP domain containing 1 [Source:NCBI gene;Acc:101168181])

HSP 1 Score: 62.003 bits (149), Expect = 1.199e-10
Identity = 68/264 (25.76%), Postives = 116/264 (43.94%), Query Frame = 1 
Query:   94 KKGKYECKLKPSTRGFFITCNGFEKEAVIESYKMLNEAVVRL----DKTNSQVELKDNESIIPINKXXXXXXXXXXXILSALKKE----KICESKQ--LFQQMSIGIKNCIFINNKSSYSTNELVNSVFACIKTSELPPAKYISRLLPVSTTCDSNIENIKLNFNSSWEVFVKNRNPANVVKKYHVDFKARHFDKINKMDVIKIVQDTLKDTCSEYEGTLN-----DYMPGIVIIYFNVLCKVTCISFLEDYQSNFKYNVQQFL 840
            K+ K   +L+   +G  ITCN  +++   E+  +LNE   +L       N+     + E  + +                ALKKE    +   +KQ   FQ +  G  N IFI  ++    ++L++ +   + TS+   ++ I R+LPV+ TC +  E++     +  E + K  N A     Y + FKAR+     + ++IK +   +        G LN     D     + I   V+  V CIS ++DY    KYNVQ+ +
Sbjct:   24 KRWKGSRELEVGMQGILITCNMNQRKCTAEALDLLNEYAEKLYGPEKLPNANGGSSEEEEDVDV----------------ALKKEVAQLQASNTKQERRFQALESGANNVIFIKTQN-MEPDKLIHQILTDLHTSKKKKSRVILRMLPVTGTCKAFQEDMVKYLTTYLEPWFKTPNCAT----YKIAFKARNSSHNKRDEIIKSIAGIV--------GKLNPKNKVDLTNPELTIIVEVIKAVCCISVVKDYTLYRKYNVQEVV 258
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BLAST of THUMP domain-containing protein 1 vs. Planmine SMEST
Match: SMESG000006826.1 (SMESG000006826.1)

HSP 1 Score: 500.745 bits (1288), Expect = 0.000e+0
Identity = 260/264 (98.48%), Postives = 260/264 (98.48%), Query Frame = 1 
Query:   49 MMKRNEKSCTKSKYFKKGKYECKLKPSTRGFFITCNGFEKEAVIESYKMLNEAVVRLDKTNSQVELKDNESIIPINKXXXXXXXXXXXILSALKKEKICESKQLFQQMSIGIKNCIFINNKSSYSTNELVNSVFACIKTSELPPAKYISRLLPVSTTCDSNIENIKLNFNSSWEVFVKNRNPANVVKKYHVDFKARHFDKINKMDVIKIVQDTLKDTCSEYEGTLNDYMPGIVIIYFNVLCKVTCISFLEDYQSNFKYNVQQFL 840
            MMKRNEKSCTKSKYFKKGKYECKLKPSTRGFFITCNGFEKEAVIESYKMLNEAVVRLDKTNSQVELKDNESIIPINKEEEDEDESDSDILSALKKEKICESKQLFQQMSIGIKNCIFINNKSSYSTNELVNSVFACIKTSELPPAKYISRLLPVSTTCDSNIENIKLNFNSSWE FVKNRNPAN VKKYHVDFKARHFDKI KMDVIKIVQDTLKDT SEYEGTLNDYMPGIVIIYFNVLCKVTCISFLEDYQSNFKYNVQQFL
Sbjct:    1 MMKRNEKSCTKSKYFKKGKYECKLKPSTRGFFITCNGFEKEAVIESYKMLNEAVVRLDKTNSQVELKDNESIIPINKEEEDEDESDSDILSALKKEKICESKQLFQQMSIGIKNCIFINNKSSYSTNELVNSVFACIKTSELPPAKYISRLLPVSTTCDSNIENIKLNFNSSWEAFVKNRNPANAVKKYHVDFKARHFDKITKMDVIKIVQDTLKDTSSEYEGTLNDYMPGIVIIYFNVLCKVTCISFLEDYQSNFKYNVQQFL 264
The following BLAST results are available for this feature:
BLAST of THUMP domain-containing protein 1 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 3
Match NameE-valueIdentityDescription
THUMPD12.585e-1024.30THUMP domain containing 1 [Source:HGNC Symbol;Acc:... [more]
THUMPD12.585e-1024.30THUMP domain containing 1 [Source:HGNC Symbol;Acc:... [more]
THUMPD12.585e-1024.30THUMP domain containing 1 [Source:HGNC Symbol;Acc:... [more]
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BLAST of THUMP domain-containing protein 1 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 1
Match NameE-valueIdentityDescription
W02G9.35.315e-725.96pep chromosome:WBcel235:V:2672986:2674026:1 gene:W... [more]
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BLAST of THUMP domain-containing protein 1 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 1
Match NameE-valueIdentityDescription
CG150147.956e-624.75gene:FBgn0035532 transcript:FBtr0073340[more]
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BLAST of THUMP domain-containing protein 1 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of THUMP domain-containing protein 1 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 2
Match NameE-valueIdentityDescription
thumpd13.169e-1127.06THUMP domain containing 1 [Source:NCBI gene;Acc:39... [more]
thumpd11.026e-726.25THUMP domain containing 1 [Source:NCBI gene;Acc:39... [more]
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BLAST of THUMP domain-containing protein 1 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 1
Match NameE-valueIdentityDescription
Thumpd11.367e-1126.21THUMP domain containing 1 [Source:MGI Symbol;Acc:M... [more]
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BLAST of THUMP domain-containing protein 1 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 3
Match NameE-valueIdentityDescription
sp|Q24K03|THUM1_BOVIN2.549e-1125.19THUMP domain-containing protein 1 OS=Bos taurus OX... [more]
sp|Q99J36|THUM1_MOUSE9.565e-1126.21THUMP domain-containing protein 1 OS=Mus musculus ... [more]
sp|Q9NXG2|THUM1_HUMAN1.242e-924.30THUMP domain-containing protein 1 OS=Homo sapiens ... [more]
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BLAST of THUMP domain-containing protein 1 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
A0A564YGX81.645e-2029.67Uncharacterized protein OS=Hymenolepis diminuta OX... [more]
A0A158REQ65.425e-2025.72Uncharacterized protein OS=Hydatigena taeniaeformi... [more]
A0A068XZJ01.691e-1926.71THUMP domain containing protein 1 OS=Echinococcus ... [more]
A0A0R3S9I82.231e-1929.67Uncharacterized protein OS=Hymenolepis diminuta OX... [more]
W6UTU91.236e-1826.62Porphobilinogen deaminase OS=Echinococcus granulos... [more]
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BLAST of THUMP domain-containing protein 1 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 2
Match NameE-valueIdentityDescription
thumpd16.514e-1428.57THUMP domain containing 1 [Source:NCBI gene;Acc:10... [more]
thumpd19.127e-1428.57THUMP domain containing 1 [Source:NCBI gene;Acc:10... [more]
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BLAST of THUMP domain-containing protein 1 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 2
Match NameE-valueIdentityDescription
thumpd15.524e-721.05THUMP domain containing 1 [Source:ZFIN;Acc:ZDB-GEN... [more]
thumpd11.907e-620.93THUMP domain containing 1 [Source:ZFIN;Acc:ZDB-GEN... [more]
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BLAST of THUMP domain-containing protein 1 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of THUMP domain-containing protein 1 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of THUMP domain-containing protein 1 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 1
Match NameE-valueIdentityDescription
thumpd11.199e-1025.76THUMP domain containing 1 [Source:NCBI gene;Acc:10... [more]
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BLAST of THUMP domain-containing protein 1 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 1
Match NameE-valueIdentityDescription
SMESG000006826.10.000e+098.48SMESG000006826.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30013367 ID=SMED30013367|Name=THUMP domain-containing protein 1|organism=Schmidtea mediterranea sexual|type=transcript|length=884bp
GTTTTGTTTAAATATACACATTTTAAAACTAAGAACTTTTAACTATATAT
GATGAAAAGGAATGAAAAATCATGCACAAAATCAAAATATTTTAAAAAAG
GTAAATATGAATGTAAATTAAAACCTTCAACTCGTGGATTTTTTATTACA
TGCAATGGCTTTGAAAAAGAGGCAGTTATCGAATCATATAAAATGCTAAA
TGAAGCTGTTGTACGATTGGATAAAACGAATTCTCAAGTTGAATTAAAAG
ATAACGAATCAATTATTCCAATTAATAAAGAAGAGGAAGATGAAGATGAA
TCTGATTCCGATATTTTATCAGCTCTTAAAAAAGAAAAAATTTGTGAAAG
TAAACAACTTTTTCAACAAATGAGTATTGGTATAAAAAATTGTATATTTA
TTAACAACAAAAGTTCTTACTCTACTAATGAATTAGTAAACTCGGTATTT
GCATGTATTAAAACTTCAGAACTTCCTCCAGCAAAATATATAAGTAGGTT
GCTACCAGTATCAACTACGTGTGATAGTAATATAGAAAATATAAAATTGA
ATTTCAATTCAAGCTGGGAAGTTTTTGTCAAGAATCGAAATCCAGCTAAT
GTGGTCAAAAAGTATCACGTTGATTTTAAAGCCCGTCATTTTGATAAAAT
AAACAAGATGGATGTTATTAAAATTGTACAAGATACATTAAAAGATACAT
GTTCAGAATATGAAGGCACACTAAATGATTATATGCCTGGTATAGTTATC
ATTTATTTCAATGTTTTATGCAAAGTTACTTGTATTTCGTTTTTGGAAGA
TTATCAATCCAATTTTAAGTATAATGTTCAACAATTTTTGTAGATATAAA
ATAAAATTATTGCTTATTTTGAACTCTGCGTTGA
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protein sequence of SMED30013367-orf-1

>SMED30013367-orf-1 ID=SMED30013367-orf-1|Name=SMED30013367-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=265bp
MMKRNEKSCTKSKYFKKGKYECKLKPSTRGFFITCNGFEKEAVIESYKML
NEAVVRLDKTNSQVELKDNESIIPINKEEEDEDESDSDILSALKKEKICE
SKQLFQQMSIGIKNCIFINNKSSYSTNELVNSVFACIKTSELPPAKYISR
LLPVSTTCDSNIENIKLNFNSSWEVFVKNRNPANVVKKYHVDFKARHFDK
INKMDVIKIVQDTLKDTCSEYEGTLNDYMPGIVIIYFNVLCKVTCISFLE
DYQSNFKYNVQQFL*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: biological process
TermDefinition
GO:0006400tRNA modification
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0002109X1 cell
Vocabulary: INTERPRO
TermDefinition
IPR004114THUMP_dom
IPR040183THUMPD1-like
Vocabulary: molecular function
TermDefinition
GO:0003723RNA binding
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR004114THUMP domainPFAMPF02926THUMPcoord: 89..216
e-value: 1.5E-4
score: 21.9
NoneNo IPR availableGENE3DG3DSA:3.30.2300.10coord: 159..250
e-value: 1.9E-5
score: 27.0
IPR040183THUMP domain-containing protein 1-likePANTHERPTHR13452THUMP DOMAIN CONTAINING PROTEIN 1-RELATEDcoord: 5..263
IPR040183THUMP domain-containing protein 1-likeCDDcd11717THUMP_THUMPD1_likecoord: 95..250
e-value: 6.0585E-20
score: 81.861