Guanylate cyclase domain-containing protein

Query:  163 MYGLILEGVRQFICSKYGEDHWNSILRSADIDVI-TFGTHEVYGETLIPNIIESASRFLNMTVDEIMFLNGIFFINFVSQYGYDGILRVLGRDLRDFLNGLDNLHEYLRFSYPKLKPPSFFCVNESK-TGITLQYRTRRSGYIHYVRGQITEIARQFYSTEMSIEIVSQTSE--DNVSNCIMRLHFNNKNFIQIEDLLXXXXXXXX--------XXXXXNIVFNRGMRAINCGKGMLNALPDL-PHQL-ITEYFLLTRPLIEFTWDAVMLHTNNIFELIHLDPKISSSKILREGNHSSKKRTLSRNNPSLKMRGQMKYMPEWDAIVFLGTPIMRDVESMYKAGLFINDLSMHDSSRDLVLAGXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMKKTDELLFQMIPKSVAERLRHGSEAVDTCEHFDEVTILFSDVVGFTTICSK----INPFDVVEMLNKLYSVFDELTEKHK---VYKVETIGDAYMIASGCPTVTQYHAPFIIEMSLDMIKSIGFLMDPSDHSRSLQIRVGIHTGMVVAGVVGLKMPRYCLFGDTVNTASRMESNSEPQKIHISEAT-----KAKVTDLQSYKISERGHIDIKGKGNIKTYWL 1932
            MYG +   +   +   YG + W  I + A +D    F    +Y ++   +++ +AS+ LN+   EI+ + G  F  F  + GYD ILRVLG ++R+FL  LD LH++L   YP ++ PSF C +  K  G+ L Y + R G    V G I  +A+Q + TE+ ++++ Q +E  D+    I       ++F +  D                  + FPF+I+F+R +    CG  +   LP L P    +   F L RP I+ ++  ++ H N +F L   +  +   K+  E   +  + +       L+++GQM Y+PE D+I+FL +P + +++ + + GL+++D+ +HD++RDLVL GEQ   E KL  E E    +         DE  KKTD LL+ ++P SVA  LRH        + +D VTILFS +VGF   CSK         +V +LN LY+ FD LT+  K   VYKVET+GD YM  SG P    +HA  I  ++LDM++  G +    +   S+QI +GIHTG VV GV+G +MPRYCLFG+TVN  SR E+  E  KI++SE T       + +D Q + +  RG + +KGK      W 
Sbjct:    1 MYGFVNHALELLVIRNYGPEVWEDIKKEAQLDEEGQFLVRIIYDDSKTYDLVAAASKVLNLNAGEILQMFGKMFFVFCQESGYDTILRVLGSNVREFLQNLDALHDHLATIYPGMRAPSFRCTDAEKGKGLILHYYSEREGLQDIVIGIIKTVAQQIHGTEIDMKVIQQRNEECDHTQFLIEEKESKEEDFYEDLDRFEENGTQESRISPYTFCKAFPFHIIFDRDLVVTQCGNAIYRVLPQLQPGNCSLLSVFSLVRPHIDISFHGILSHINTVFVLRSKEGLLDVEKLECEDELTGTEIS------CLRLKGQMIYLPEADSILFLCSPSVMNLDDLTRRGLYLSDIPLHDATRDLVLLGEQFREEYKLTQELEILTDRLQLTLRALEDEK-KKTDTLLYSVLPPSVANELRHKRPV--PAKRYDNVTILFSGIVGFNAFCSKHASGEGAMKIVNLLNDLYTRFDTLTDSRKNPFVYKVETVGDKYMTVSGLPEPCIHHARSICHLALDMMEIAGQVQVDGE---SVQITIGIHTGEVVTGVIGQRMPRYCLFGNTVNLTSRTETTGEKGKINVSEYTYRCLMSPENSDPQ-FHLEHRGPVSMKGKKEPMQVWF 603          

Query:  163 MYGLILEGVRQFICSKYGEDHWNSILRSADIDVI-TFGTHEVYGETLIPNIIESASRFLNMTVDEIMFLNGIFFINFVSQYGYDGILRVLGRDLRDFL----------------------NGLDNLHEYLRFSYPKLKPPSFFCVNESK-TGITLQYRTRRSGYIHYVRGQITEIARQFYSTEMSIEIVSQTSE--DNVSNCIMRLHFNNKNFIQIEDLLXXXXXXXX--------XXXXXNIVFNRGMRAINCGKGMLNALPDL-PHQL-ITEYFLLTRPLIEFTWDAVMLHTNNIFELIHLDPKISSSKILREGNHSSKKRTLSRNNPSLKMRGQMKYMPEWDAIVFLGTPIMRDVESMYKAGLFINDLSMHDSSRDLVLAGXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMKKTDELLFQMIPKSVAERLRHGSEAVDTCEHFDEVTILFSDVVGFTTICSK----INPFDVVEMLNKLYSVFDELTEKHK---VYKVETIGDAYMIASGCPTVTQYHAPFIIEMSLDMIKSIGFLMDPSDHSRSLQIRVGIHTGMVVAGVVGLKMPRYCLFGDTVNTASRMESNSEPQKIHISEAT-----KAKVTDLQSYKISERGHIDIKGKGNIKTYWL 1932
            MYG +   +   +   YG + W  I + A +D    F    +Y ++   +++ +AS+ LN+   EI+ + G  F  F  + GYD ILRVLG ++R+FL                      N LD LH++L   YP ++ PSF C +  K  G+ L Y + R G    V G I  +A+Q + TE+ ++++ Q +E  D+    I       ++F +  D                  + FPF+I+F+R +    CG  +   LP L P    +   F L RP I+ ++  ++ H N +F L   +  +   K+  E   +  + +       L+++GQM Y+PE D+I+FL +P + +++ + + GL+++D+ +HD++RDLVL GEQ   E KL  E E    +         DE  KKTD LL+ ++P SVA  LRH        + +D VTILFS +VGF   CSK         +V +LN LY+ FD LT+  K   VYKVET+GD YM  SG P    +HA  I  ++LDM++  G +    +   S+QI +GIHTG VV GV+G +MPRYCLFG+TVN  SR E+  E  KI++SE T       + +D Q + +  RG + +KGK      W 
Sbjct:    1 MYGFVNHALELLVIRNYGPEVWEDIKKEAQLDEEGQFLVRIIYDDSKTYDLVAAASKVLNLNAGEILQMFGKMFFVFCQESGYDTILRVLGSNVREFLQKNESKHISDLHHCFLGIYLCCNNLDALHDHLATIYPGMRAPSFRCTDAEKGKGLILHYYSEREGLQDIVIGIIKTVAQQIHGTEIDMKVIQQRNEECDHTQFLIEEKESKEEDFYEDLDRFEENGTQESRISPYTFCKAFPFHIIFDRDLVVTQCGNAIYRVLPQLQPGNCSLLSVFSLVRPHIDISFHGILSHINTVFVLRSKEGLLDVEKLECEDELTGTEIS------CLRLKGQMIYLPEADSILFLCSPSVMNLDDLTRRGLYLSDIPLHDATRDLVLLGEQFREEYKLTQELEILTDRLQLTLRALEDEK-KKTDTLLYSVLPPSVANELRHKRPV--PAKRYDNVTILFSGIVGFNAFCSKHASGEGAMKIVNLLNDLYTRFDTLTDSRKNPFVYKVETVGDKYMTVSGLPEPCIHHARSICHLALDMMEIAGQVQVDGE---SVQITIGIHTGEVVTGVIGQRMPRYCLFGNTVNLTSRTETTGEKGKINVSEYTYRCLMSPENSDPQ-FHLEHRGPVSMKGKKEPMQVWF 625          

Query:  283 VYGETLIPNIIESASRFLNMTVDEIMFLNGIFFINFVSQYGYDGILRVLGRDLRDFLNGLDNLHEYLRFSYPKLKPPSFFCVNESK-TGITLQYRTRRSGYIHYVRGQITEIARQFYSTEMSIEIVSQTSE--DNVSNCIMRLHFNNKNFIQIEDLLXXXXXXXX--------XXXXXNIVFNRGMRAINCGKGMLNALPDL-PHQL-ITEYFLLTRPLIEFTWDAVMLHTNNIFELIHLDPKISSSKILREGNHSSKKRTLSRNNPSLKMRGQMKYMPEWDAIVFLGTPIMRDVESMYKAGLFINDLSMHDSSRDLVLAGXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMKKTDELLFQMIPKSVAERLRHGSEAVDTCEHFDEVTILFSDVVGFTTICSK----INPFDVVEMLNKLYSVFDELTEKHK---VYKVETIGDAYMIASGCPTVTQYHAPFIIEMSLDMIKSIGFLMDPSDHSRSLQIRVGIHTGMVVAGVVGLKMPRYCLFGDTVNTASRMESNSEPQKIHISEAT-----KAKVTDLQSYKISERGHIDIKGKGNIKTYWL 1932
            +Y ++   +++ +AS+ LN+   EI+ + G  F  F  + GYD ILRVLG ++R+FL  LD LH++L   YP ++ PSF C +  K  G+ L Y + R G    V G I  +A+Q + TE+ ++++ Q +E  D+    I       ++F +  D                  + FPF+I+F+R +    CG  +   LP L P    +   F L RP I+ ++  ++ H N +F L   +  +   K+  E   +  + +       L+++GQM Y+PE D+I+FL +P + +++ + + GL+++D+ +HD++RDLVL GEQ   E KL  E E    +         DE  KKTD LL+ ++P SVA  LRH        + +D VTILFS +VGF   CSK         +V +LN LY+ FD LT+  K   VYKVET+GD YM  SG P    +HA  I  ++LDM++  G +    +   S+QI +GIHTG VV GV+G +MPRYCLFG+TVN  SR E+  E  KI++SE T       + +D Q + +  RG + +KGK      W 
Sbjct:   22 IYDDSKTYDLVAAASKVLNLNAGEILQMFGKMFFVFCQESGYDTILRVLGSNVREFLQNLDALHDHLATIYPGMRAPSFRCTDAEKGKGLILHYYSEREGLQDIVIGIIKTVAQQIHGTEIDMKVIQQRNEECDHTQFLIEEKESKEEDFYEDLDRFEENGTQESRISPYTFCKAFPFHIIFDRDLVVTQCGNAIYRVLPQLQPGNCSLLSVFSLVRPHIDISFHGILSHINTVFVLRSKEGLLDVEKLECEDELTGTEIS------CLRLKGQMIYLPEADSILFLCSPSVMNLDDLTRRGLYLSDIPLHDATRDLVLLGEQFREEYKLTQELEILTDRLQLTLRALEDEK-KKTDTLLYSVLPPSVANELRHKRPV--PAKRYDNVTILFSGIVGFNAFCSKHASGEGAMKIVNLLNDLYTRFDTLTDSRKNPFVYKVETVGDKYMTVSGLPEPCIHHARSICHLALDMMEIAGQVQVDGE---SVQITIGIHTGEVVTGVIGQRMPRYCLFGNTVNLTSRTETTGEKGKINVSEYTYRCLMSPENSDPQ-FHLEHRGPVSMKGKKEPMQVWF 583          

Query:  283 VYGETLIPNIIESASRFLNMTVDEIMFLNGIFFINFVSQYGYDGILRVLGRDLRDFLNGLDNLHEYLRFSYPKLKPPSFFCVNESK-TGITLQYRTRRSGYIHYVRGQITEIARQFYSTEMSIEIVSQTSE--DNVSNCIMRLHFNNKNFIQIEDLLXXXXXXXX--------XXXXXNIVFNRGMRAINCGKGMLNALPDL-PHQL-ITEYFLLTRPLIEFTWDAVMLHTNNIFELIHLDPKISSSKILREGNHSSKKRTLSRNNPSLKMRGQMKYMPEWDAIVFLGTPIMRDVESMYKAGLFINDLSMHDSSRDLVLAGXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMKKTDELLFQMIPKSVAERLRHGSEAVDTCEHFDEVTILFSDVVGFTTICSK----INPFDVVEMLNKLYSVFDELTEKHK---VYKVETIGDAYMIASGCPTVTQYHAPFIIEMSLDMIKSIGFLMDPSDHSRSLQIRVGIHTGMVVAGVVGLKMPRYCLFGDTVNTASRMESNSEPQKIHISEAT-----KAKVTDLQSYKISERGHIDIKGKGNIKTYWL 1932
            +Y ++   +++ +AS+ LN+   EI+ + G  F  F  + GYD ILRVLG ++R+FL  LD LH++L   YP ++ PSF C +  K  G+ L Y + R G    V G I  +A+Q + TE+ ++++ Q +E  D+    I       ++F +  D                  + FPF+I+F+R +    CG  +   LP L P    +   F L RP I+ ++  ++ H N +F L   +  +   K+  E   +  + +       L+++GQM Y+PE D+I+FL +P + +++ + + GL+++D+ +HD++RDLVL GEQ   E KL  E E    +         DE  KKTD LL+ ++P SVA  LRH        + +D VTILFS +VGF   CSK         +V +LN LY+ FD LT+  K   VYKVET+GD YM  SG P    +HA  I  ++LDM++  G +    +   S+QI +GIHTG VV GV+G +MPRYCLFG+TVN  SR E+  E  KI++SE T       + +D Q + +  RG + +KGK      W 
Sbjct:   74 IYDDSKTYDLVAAASKVLNLNAGEILQMFGKMFFVFCQESGYDTILRVLGSNVREFLQNLDALHDHLATIYPGMRAPSFRCTDAEKGKGLILHYYSEREGLQDIVIGIIKTVAQQIHGTEIDMKVIQQRNEECDHTQFLIEEKESKEEDFYEDLDRFEENGTQESRISPYTFCKAFPFHIIFDRDLVVTQCGNAIYRVLPQLQPGNCSLLSVFSLVRPHIDISFHGILSHINTVFVLRSKEGLLDVEKLECEDELTGTEIS------CLRLKGQMIYLPEADSILFLCSPSVMNLDDLTRRGLYLSDIPLHDATRDLVLLGEQFREEYKLTQELEILTDRLQLTLRALEDEK-KKTDTLLYSVLPPSVANELRHKRPV--PAKRYDNVTILFSGIVGFNAFCSKHASGEGAMKIVNLLNDLYTRFDTLTDSRKNPFVYKVETVGDKYMTVSGLPEPCIHHARSICHLALDMMEIAGQVQVDGE---SVQITIGIHTGEVVTGVIGQRMPRYCLFGNTVNLTSRTETTGEKGKINVSEYTYRCLMSPENSDPQ-FHLEHRGPVSMKGKKEPMQVWF 635          

Query:  370 GIFFINFVSQYGYDGILRVLGRDLRDFLNGLDNLHEYLRFSYPKLKPPSFFCVNESK-TGITLQYRTRRSGYIHYVRGQITEIARQFYSTEMSIEIVSQTSE--DNVSNCIMRLHFNNKNFIQIEDLLXXXXXXXX--------XXXXXNIVFNRGMRAINCGKGMLNALPDL-PHQL-ITEYFLLTRPLIEFTWDAVMLHTNNIFELIHLDPKISSSKILREGNHSSKKRTLSRNNPSLKMRGQMKYMPEWDAIVFLGTPIMRDVESMYKAGLFINDLSMHDSSRDLVLAGXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMKKTDELLFQMIPKSVAERLRHGSEAVDTCEHFDEVTILFSDVVGFTTICSK----INPFDVVEMLNKLYSVFDELTEKHK---VYKVETIGDAYMIASGCPTVTQYHAPFIIEMSLDMIKSIGFLMDPSDHSRSLQIRVGIHTGMVVAGVVGLKMPRYCLFGDTVNTASRMESNSEPQKIHISEAT-----KAKVTDLQSYKISERGHIDIKGKGNIKTYWL 1932
            G  F  F  + GYD ILRVLG ++R+FL  LD LH++L   YP ++ PSF C +  K  G+ L Y + R G    V G I  +A+Q + TE+ ++++ Q +E  D+    I       ++F +  D                  + FPF+I+F+R +    CG  +   LP L P    +   F L RP I+ ++  ++ H N +F L   +  +   K+  E   +  + +       L+++GQM Y+PE D+I+FL +P + +++ + + GL+++D+ +HD++RDLVL GEQ   E KL  E E    +         DE  KKTD LL+ ++P SVA  LRH        + +D VTILFS +VGF   CSK         +V +LN LY+ FD LT+  K   VYKVET+GD YM  SG P    +HA  I  ++LDM++  G +    +   S+QI +GIHTG VV GV+G +MPRYCLFG+TVN  SR E+  E  KI++SE T       + +D Q + +  RG + +KGK      W 
Sbjct:    3 GKMFFVFCQESGYDTILRVLGSNVREFLQNLDALHDHLATIYPGMRAPSFRCTDAEKGKGLILHYYSEREGLQDIVIGIIKTVAQQIHGTEIDMKVIQQRNEECDHTQFLIEEKESKEEDFYEDLDRFEENGTQESRISPYTFCKAFPFHIIFDRDLVVTQCGNAIYRVLPQLQPGNCSLLSVFSLVRPHIDISFHGILSHINTVFVLRSKEGLLDVEKLECEDELTGTEIS------CLRLKGQMIYLPEADSILFLCSPSVMNLDDLTRRGLYLSDIPLHDATRDLVLLGEQFREEYKLTQELEILTDRLQLTLRALEDEK-KKTDTLLYSVLPPSVANELRHKRPV--PAKRYDNVTILFSGIVGFNAFCSKHASGEGAMKIVNLLNDLYTRFDTLTDSRKNPFVYKVETVGDKYMTVSGLPEPCIHHARSICHLALDMMEIAGQVQVDGE---SVQITIGIHTGEVVTGVIGQRMPRYCLFGNTVNLTSRTETTGEKGKINVSEYTYRCLMSPENSDPQ-FHLEHRGPVSMKGKKEPMQVWF 535          

Query:  163 MYGLILEGVRQFICSKYGEDHWNSILRSADIDVITFGTHEVYGETLIPNIIESASRFLNMTVDEIMFLNGIFFINFVSQYGYDGILRVLGRDLRDFLNGLDNLHEYLRFSYPKLKPPSFFCVNESKTGITLQYRTRRSGYIHYVRGQITEIARQFYSTEMSIEIVSQTSEDNVSNCIMRLHFNNKNFIQ-----------IEDLLXXXXXXXXXXXXXNIVFNRGMRAINCGKGMLNALPDLPHQLITEYFLLTRPLIEFTWDAVMLHTNNIFELIHLDP-KISSSKILREGNHSSKKRTLSRNNPS-------LKMRGQMKYMPEWDAIVFLGTPIMRDVESMYKAGLFINDLSMHDSSRDLVLAGXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMKKTDELLFQMIPKSVAERLRHGSEAVDTCEHFDEVTILFSDVVGFTTICSKINPFDVVEMLNKLYSVFDELTEKHKVYKVETIGDAYMIASGCPTVTQYHAPFIIEMSLDMIKSIGFLMDPSDHSRSLQIRVGIHTGMVVAGVVGLKMPRYCLFGDTVNTASRMESNSEPQKIHISEATKAKV--TDLQSYKISERGHIDIKGKGNIKTYWL----DGHNLENPKAVAS 1971
            MYGLI++ +  +I  KYGE  W+ +   + +   TF   + + E L   +I +        VDE+M   G  F  F++++ ++ +LRVLGR    FLNGLDNLHEYLRF++PKLKPPSF+C +ES+TG+TL YR++R G++HYV+GQI  I+++ + TE+ IE++    + N+ + IMRLHFNN +F +           I + + + S++FF++FPF IVFNRGMR  N G G+L  +  +  + I + FLL RP I F W+ +MLH+NNIFELI  DP +     IL        + T  R+          L ++GQM YM EW++I F+G P+M  +  MYK+GLFIND ++HDSSRDLVLA  QQSAELKL L QE++KS+ + E++++L +  ++TD+LL+QM+PKSVA +LRHG  AV  CE FD VTILF+D+V FT +CS + P +V+E L  +Y+ FD++ + H VYKVETIGDAYM+ SG PT T++ A FI++ +   +   G +++ ++    + IR G+H+G VVAGVVGL MPRYCLFG+TV  A++ME NS P KI +SE T  K+  +D   Y+   R  I+IK    I+T+++      H + +P+   S
Sbjct:    1 MYGLIIDHIATYIKEKYGESTWSEVKFVSGVTDDTFQMDKKFSEGLSHKLIWACHDVTGDPVDELMTNIGTSFYKFLTKFEFNKVLRVLGRTFPQFLNGLDNLHEYLRFTFPKLKPPSFYCEHESRTGLTLHYRSKRRGFLHYVQGQIRNISQELFQTEVVIELLDIEHDLNLEHVIMRLHFNNLDFNRQGTAYRNLNDSILEKVKITSDIFFDIFPFIIVFNRGMRIRNIGIGLLRVMAGIVGKKINQTFLLMRPFIRFRWEEIMLHSNNIFELISSDPIQEDEDGILVYKTTDVDQMTEERHRMGDGEREKFLSLKGQMFYMEEWESICFVGIPVMSHLPQMYKSGLFINDFALHDSSRDLVLASTQQSAELKLLLHQEAQKSRNMRENMNRLKKERRRTDKLLYQMLPKSVANQLRHGESAVACCERFDSVTILFTDIVEFTKMCSSLTPLEVIEFLKVIYTNFDKIIDTHGVYKVETIGDAYMVVSGAPTKTEHDAEFILDCASQFLVEAGKMVNMNNKIHKIDIRAGVHSGSVVAGVVGLSMPRYCLFGETVYVANKMEQNSSPMKILVSETTHNKIEESDPGLYQFERREEIEIKDDQTIQTFFVVSRHGPHRVPSPRNCES 628          

Query:  346 VDEIMFLNGIFFINFVSQYGYDGILRVLGRDLRDFLNGLDNLHEYLRFSYPKLKPPSFFCVNESKTGITLQYRTRRSGYIHYVRGQITEIARQFYSTEMSIEIVSQTSEDNVSNCIMRLHFNNKNFIQ-----------IEDLLXXXXXXXXXXXXXNIVFNRGMRAINCGKGMLNALPDLPHQLITEYFLLTRPLIEFTWDAVMLHTNNIFELIHLDP-KISSSKILREGNHSSKKRTLSRNNPS-------LKMRGQMKYMPEWDAIVFLGTPIMRDVESMYKAGLFINDLSMHDSSRDLVLAGXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMKKTDELLFQMIPKSVAERLRHGSEAVDTCEHFDEVTILFSDVVGFTTICSKINPFDVVEMLNKLYSVFDELTEKHKVYKVETIGDAYMIASGCPTVTQYHAPFIIEMSLDMIKSIGFLMDPSDHSRSLQIRVGIHTGMVVAGVVGLKMPRYCLFGDTVNTASRMESNSEPQKIHISEATKAKV--TDLQSYKISERGHIDIKGKGNIKTYWL----DGHNLENPKAVAS 1971
            VDE+M   G  F  F++++ ++ +LRVLGR    FLNGLDNLHEYLRF++PKLKPPSF+C +ES+TG+TL YR++R G++HYV+GQI  I+++ + TE+ IE++    + N+ + IMRLHFNN +F +           I + + + S++FF++FPF IVFNRGMR  N G G+L  +  +  + I + FLL RP I F W+ +MLH+NNIFELI  DP +     IL        + T  R+          L ++GQM YM EW++I F+G P+M  +  MYK+GLFIND ++HDSSRDLVLA  QQSAELKL L QE++KS+ + E++++L +  ++TD+LL+QM+PKSVA +LRHG  AV  CE FD VTILF+D+V FT +CS + P +V+E L  +Y+ FD++ + H VYKVETIGDAYM+ SG PT T++ A FI++ +   +   G +++ ++    + IR G+H+G VVAGVVGL MPRYCLFG+TV  A++ME NS P KI +SE T  K+  +D   Y+   R  I+IK    I+T+++      H + +P+   S
Sbjct:   25 VDELMTNIGTSFYKFLTKFEFNKVLRVLGRTFPQFLNGLDNLHEYLRFTFPKLKPPSFYCEHESRTGLTLHYRSKRRGFLHYVQGQIRNISQELFQTEVVIELLDIEHDLNLEHVIMRLHFNNLDFNRQGTAYRNLNDSILEKVKITSDIFFDIFPFIIVFNRGMRIRNIGIGLLRVMAGIVGKKINQTFLLMRPFIRFRWEEIMLHSNNIFELISSDPIQEDEDGILVYKTTDVDQMTEERHRMGDGEREKFLSLKGQMFYMEEWESICFVGIPVMSHLPQMYKSGLFINDFALHDSSRDLVLASTQQSAELKLLLHQEAQKSRNMRENMNRLKKERRRTDKLLYQMLPKSVANQLRHGESAVACCERFDSVTILFTDIVEFTKMCSSLTPLEVIEFLKVIYTNFDKIIDTHGVYKVETIGDAYMVVSGAPTKTEHDAEFILDCASQFLVEAGKMVNMNNKIHKIDIRAGVHSGSVVAGVVGLSMPRYCLFGETVYVANKMEQNSSPMKILVSETTHNKIEESDPGLYQFERREEIEIKDDQTIQTFFVVSRHGPHRVPSPRNCES 591          

Query:  562 RTRRSGYIHYVRGQITEIARQFYSTEMSIEIVSQTSEDNVSNCIMRLHFNNKNFIQ-----------IEDLLXXXXXXXXXXXXXNIVFNRGMRAINCGKGMLNALPDLPHQLITEYFLLTRPLIEFTWDAVMLHTNNIFELIHLDP-KISSSKILREGNHSSKKRTLSRNNPS-------LKMRGQMKYMPEWDAIVFLGTPIMRDVESMYKAGLFINDLSMHDSSRDLVLAGXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMKKTDELLFQMIPKSVAERLRHGSEAVDTCEHFDEVTILFSDVVGFTTICSKINPFDVVEMLNKLYSVFDELTEKHKVYKVETIGDAYMIASGCPTVTQYHAPFIIEMSLDMIKSIGFLMDPSDHSRSLQIRVGIHTGMVVAGVVGLKMPRYCLFGDTVNTASRMESNSEPQKIHISEATKAKV--TDLQSYKISERGHIDIKGKGNIKTYWL----DGHNLENPKAVAS 1971
            R++R G++HYV+GQI  I+++ + TE+ IE++    + N+ + IMRLHFNN +F +           I + + + S++FF++FPF IVFNRGMR  N G G+L  +  +  + I + FLL RP I F W+ +MLH+NNIFELI  DP +     IL        + T  R+          L ++GQM YM EW++I F+G P+M  +  MYK+GLFIND ++HDSSRDLVLA  QQSAELKL L QE++KS+ + E++++L +  ++TD+LL+QM+PKSVA +LRHG  AV  CE FD VTILF+D+V FT +CS + P +V+E L  +Y+ FD++ + H VYKVETIGDAYM+ SG PT T++ A FI++ +   +   G +++ ++    + IR G+H+G VVAGVVGL MPRYCLFG+TV  A++ME NS P KI +SE T  K+  +D   Y+   R  I+IK    I+T+++      H + +P+   S
Sbjct:   10 RSKRRGFLHYVQGQIRNISQELFQTEVVIELLDIEHDLNLEHVIMRLHFNNLDFNRQGTAYRNLNDSILEKVKITSDIFFDIFPFIIVFNRGMRIRNIGIGLLRVMAGIVGKKINQTFLLMRPFIRFRWEEIMLHSNNIFELISSDPIQEDEDGILVYKTTDVDQMTEERHRMGDGEREKFLSLKGQMFYMEEWESICFVGIPVMSHLPQMYKSGLFINDFALHDSSRDLVLASTQQSAELKLLLHQEAQKSRNMRENMNRLKKERRRTDKLLYQMLPKSVANQLRHGESAVACCERFDSVTILFTDIVEFTKMCSSLTPLEVIEFLKVIYTNFDKIIDTHGVYKVETIGDAYMVVSGAPTKTEHDAEFILDCASQFLVEAGKMVNMNNKIHKIDIRAGVHSGSVVAGVVGLSMPRYCLFGETVYVANKMEQNSSPMKILVSETTHNKIEESDPGLYQFERREEIEIKDDQTIQTFFVVSRHGPHRVPSPRNCES 504          

Query:  163 MYGLILEGVRQFICSKYGEDHWNSILRSADIDVITFGTHEVYGETLIPNIIESASRFLNMTVDEIMFLNGIFFINFVSQYGYDGILRVLGRDLRDFLNGLDNLHEYLRFSYPKLKPPSFFCVNESKTGITLQYRTRRSGYIHYVRGQITEIARQFYSTEMSIEIVSQTSEDNVSNCIMRLHFNNKNFIQ----------IEDLLXXXXXXXXXXXXXNIVFNRGMRAINCGKGMLNALPDLPHQLITEYFLLTRPLIEFTWDAVMLHTNNIFELIHLDPKISSSK--------ILREGNHSSKKRTLSRNN----PSLKMRGQMKYMPEWDAIVFLGTPIMRDVESMYKAGLFINDLSMHDSSRDLVLAGXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMKKTDELLFQMIPKSVAER-LRHGSEAVDTCEHFDEVTILFSDVVGFTTICSKINPFDVVEMLNKLYSVFDELTEKHKVYKVETIGDAYMIASGCPTVTQYHAPFIIEMSLDMIKSI-GFLMDPSDHSRSLQIRVGIHTGMVVAGVVGLKMPRYCLFGDTVNTASRME-SNSEPQKIHISEATKAKVTDLQS--YKISERGHIDIKGKGNIKTYWLD 1935
            MYGL++EGVR  I   +G      + +   +   +  TH+ Y E ++P + ++         ++I  L G FF+ F+ + GY  ++ V+GR   DF+ GLDN+HEY RFSYPKL+ PSF+C +ES+ G+ L YR+RR+GY+ YV GQ+ E+AR FY  ++ I+++ +  +   +  ++++ F+N    Q          + + LPV ++ F ++FPF+I FN+ +  +  G+G+LN +P++   L+T+ F L RP I+FT + +M+H N +F++  L P +  ++         + E   S +K+T+  N     P + +RG +  +   +  + L T ++  +++M+K GL++ND    D +R++++A  Q+S  LK  LE E  +S+ L E   ++ E  K    LL QM+P  VA+  +R GS  VD CE F+ V+I F  V  F+ I   I  F+VV +LN +YS  D + + H VYKVETIG++YMI++GCP    Y A  + +  L+M+  I  F     D  + + I+ GI TG VV GVVG++ PRYCLFGDTVNTASRME SN  P  I I + TK +V    S  ++I  +G++ +KGKG+++ Y ++
Sbjct:    1 MYGLVIEGVRFMIQENWGPQVLLQVQKLTSLSEKSVSTHDQYSEHVVPQMFKAIHEITGTPYEQIGVLAGRFFVQFLIRNGYGDLMNVMGRRFSDFIKGLDNIHEYFRFSYPKLRAPSFYCKSESEDGLILHYRSRRTGYLSYVIGQLVELARVFYQLDIGIQVLKKKEKGRFTFVVLKISFDNVGLGQDLKLKERVKNLNEYLPVDTKSFLQMFPFHIAFNKKLEILMAGQGLLNLMPNIQGLLMTDVFDLQRPCIKFTAEGIMVHQNCVFQIESLHPVVKQTEENITVQINDITEDKVSLEKKTVMDNEYESLPYVTLRGPITVLKSSETFLLLATCVVDTLDTMFKMGLYLNDFGESDCNREIIMATIQKSDTLKTMLENEKRRSEVLTEMTREISEAKKTARTLLTQMMPYEVAQTMMRSGS--VDHCEAFECVSIGFIRVCDFSKISLFIEAFEVVNLLNTIYSHLDSIVDTHGVYKVETIGESYMISAGCPYRDDYDAEMVSDCCLEMVSHIKSFEYQSHDAVKKVLIKCGIFTGPVVGGVVGVRTPRYCLFGDTVNTASRMESSNQTPMTIQIGQRTKDRVEKQASGAFRIKPKGNVFVKGKGDMRVYEIE 616          

Query:  163 MYGLILEGVRQFICSKYGEDHWNSILRSADIDVITFGTHEVYGETLIPNIIESASRFLNMTVDEIMFLNGIFFINFVSQYGYDGILRVLGRDLRDFLNGLDNLHEYLRFSYPKLKPPSFFCVNESKTGITLQYRTRRSGYIHYVRGQITEIARQFYSTEMSIEIVSQTSEDNVSNCIMRLHFNNKNFIQ----------IEDLLXXXXXXXXXXXXXNIVFNRGMRAINCGKGMLNALPDLPHQLITEYFLLTRPLIEFTWDAVMLHTNNIFELIHLDPKISSSK--------ILREGNHSSKKRTLSRNN------PSLKMRGQMKYMPEWDAIVFLGTPIMRDVESMYKAGLFINDLSMHDSSRDLVLAGXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMKKTDELLFQMIPKSVAER-LRHGSEAVDTCEHFDEVTILFSDVVGFTTICSKINPFDVVEMLNKLYSVFDELTEKHKVYKVETIGDAYMIASGCPTVTQYHAPFIIEMSLDMIKSI-GFLMDPSDHSRSLQIRVGIHTGMVVAGVVGLKMPRYCLFGDTVNTASRME-SNSEPQKIHISEATKAKVTDLQS--YKISERGHIDIKGKGNIKTYWLD 1935
            MYGL++EGVR  I   +G      + +   +   +  TH+ Y E ++P + ++         ++I  L G FF+ F+ + GY  ++ V+GR   DF+ GLDN+HEY RFSYPKL+ PSF+C +ES+ G+ L YR+RR+GY+ YV GQ+ E+AR FY  ++ I+++ +  +   +  ++++ F+N    Q          + + LPV ++ F ++FPF+I FN+ +  +  G+G+LN +P++   L+T+ F L RP I+FT + +M+H N +F++  L P +  ++         + E   S +K+T+  N       P + +RG +  +   +  + L T ++  +++M+K GL++ND    D +R++++A  Q+S  LK  LE E  +S+ L E   ++ E  K    LL QM+P  VA+  +R GS  VD CE F+ V+I F  V  F+ I   I  F+VV +LN +YS  D + + H VYKVETIG++YMI++GCP    Y A  + +  L+M+  I  F     D  + + I+ GI TG VV GVVG++ PRYCLFGDTVNTASRME SN  P  I I + TK +V    S  ++I  +G++ +KGKG+++ Y ++
Sbjct:    1 MYGLVIEGVRFMIQENWGPQVLLQVQKLTSLSEKSVSTHDQYSEHVVPQMFKAIHEITGTPYEQIGVLAGRFFVQFLIRNGYGDLMNVMGRRFSDFIKGLDNIHEYFRFSYPKLRAPSFYCKSESEDGLILHYRSRRTGYLSYVIGQLVELARVFYQLDIGIQVLKKKEKGRFTFVVLKISFDNVGLGQDLKLKERVKNLNEYLPVDTKSFLQMFPFHIAFNKKLEILMAGQGLLNLMPNIQGLLMTDVFDLQRPCIKFTAEGIMVHQNCVFQIESLHPVVKQTEENITVQINDITEDKVSLEKKTVMDNEYGLESLPYVTLRGPITVLKSSETFLLLATCVVDTLDTMFKMGLYLNDFGESDCNREIIMATIQKSDTLKTMLENEKRRSEVLTEMTREISEAKKTARTLLTQMMPYEVAQTMMRSGS--VDHCEAFECVSIGFIRVCDFSKISLFIEAFEVVNLLNTIYSHLDSIVDTHGVYKVETIGESYMISAGCPYRDDYDAEMVSDCCLEMVSHIKSFEYQSHDAVKKVLIKCGIFTGPVVGGVVGVRTPRYCLFGDTVNTASRMESSNQTPMTIQIGQRTKDRVEKQASGAFRIKPKGNVFVKGKGDMRVYEIE 618          

Query:  163 MYGLILEGVRQFICSKYGEDHWNSILRSADIDVITFGTHEVYGETLIPNIIESASRFLNMTVDEIMFLNGIFFINFVSQYGYDGILRVLGRDLRDFLNGLDNLHEYLRFSYPKLKPPSFFCVNESKTGITLQYRTRRSGYIHYVRGQITEIARQFYSTEMSIEIVSQTSEDNVSNCIMRLHFNNKNF-------IQIEDLLXXXXXXXXXXXXXNIVFNRGMRAINCGKGMLNALPDLPHQLITEYFLLTRPLIEFTWDAVMLHTNNIFELIHLDP-----KISSSKILREGNHSSKKRTLSRNNPSLKMRGQMKYMPEWDAIVFLGTPIMRDVESMYKAGLFINDLSMHDSSRDLVLAGXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMKKTDELLFQMIPKSVAERLRHGSEAVDTCEHFDEVTILFSDVVGFTTICSKINPFDVVEMLNKLYSVFDELTEKHKVYKVETIGDAYMIASGCPTVTQYHAPFIIEMSLDMIKSIGFLMDPSDHSRSLQIRVGIHTGMVVAGVVGLKMPRYCLFGDTVNTASRMESNSEPQKIHISEATKAKVTDLQSYKISERGHIDIKGKGNIKTYWLD 1935
            MYGL+LE + ++I S YGE+ W  I R A ID  +F  H+VY E L+  + + A + L ++  + M   G++F+ FV QYGYD +L VLGR +RDFLNGLDNLHEYL+FSYP+++ PSF C NE+K G+TL YR++R G+++Y  GQI E+AR FY  EM IE+V +    +  +   +L F+N+ F        + E  LP+ + V FE+FPF +VF   M   + G  ++  LP+L  + IT +F L RPLI F +  ++  TNNIFEL+ +DP      + +  +L+  + S  ++       SL+++GQM YM  W  I+FLGTP+M D+ S+   GL+INDLSMHD SRDL+LAG QQS ELKLAL+QE +KSKKLEES+  LDE M++TDELL+QMIPK VA+RLR G   +DTCE FD V+ILFSD+V FT ICS+I P +VV MLN +YS+FD+LTE++ VYKVETIGDAYM+ +G P     HA  + +M+LDM+ +I  L DPS   + L+IRVG+H+G VVAG+VGLKMPRYCLFGDTVNTASRMES S   K+HISE+TK  +    +YKI ERG ID+KGKG + TYWL+
Sbjct:    1 MYGLLLENLSEYIKSVYGEEKWEDIRRQAGIDSPSFSVHQVYPENLLQKLAKKAQQVLGVSERDFMDQMGVYFVGFVGQYGYDRVLSVLGRHMRDFLNGLDNLHEYLKFSYPRMRAPSFICENETKQGLTLHYRSKRRGFVYYTMGQIREVARYFYHKEMHIELVREEILFDTVHVTFQLTFDNRAFTLASLAMTREEKHLPISAHVLFEIFPFCMVFGADMVVRSIGNSLMVILPELLGKKITAWFDLVRPLIAFKFQTILNRTNNIFELVTVDPVTERFDVQNEDLLQHEDGSEPEK-------SLRLKGQMVYMENWRMIMFLGTPVMPDLTSLITTGLYINDLSMHDFSRDLMLAGTQQSVELKLALDQEQQKSKKLEESMRLLDEEMRRTDELLYQMIPKQVADRLRRGENPIDTCEMFDSVSILFSDIVTFTEICSRITPMEVVSMLNAMYSIFDKLTERNSVYKVETIGDAYMVVAGAPDKDANHAERVCDMALDMVDAITDLKDPST-GQHLRIRVGVHSGAVVAGIVGLKMPRYCLFGDTVNTASRMESTSIAMKVHISESTKVLIG--PNYKIIERGEIDVKGKGTMGTYWLE 593          

Query:  163 MYGLILEGVRQFICSKYGEDHWNSILRSADIDVITFGTHEVYGETLIPNIIESASRFLNMTVDEIMFLNGIFFINFVSQYGYDGILRVLGRDLRDFLNGLDNLHEYLRFSYPKLKPPSFFCVNESKTGITLQYRTRRSGYIHYVRGQITEIARQFYSTEMSIEIVSQTSEDNVSNCIMRLHFNNKNF-------IQIEDLLXXXXXXXXXXXXXNIVFNRGMRAINCGKGMLNALPDLPHQLITEYFLLTRPLIEFTWDAVMLHTNNIFELIHLDP-----KISSSKILREGNHSSKKRTLSRNNPSLKMRGQMKYMPEWDAIVFLGTPIMRDVESMYKAGLFINDLSMHDSSRDLVLAGXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMKKTDELLFQMIPKSVAERLRHGSEAVDTCEHFDEVTILFSDVVGFTTICSKINPFDVVEMLNKLYSVFDELTEKHKVYKVETIGDAYMIASGCPTVTQYHAPFIIEMSLDMIKSIGFLMDPSDHSRSLQIRVGIHTGMVVAGVVGLKMPRYCLFGDTVNTASRMESNSEPQKIHISEATKAKVTDLQSYKISERGHIDIKGKGNIKTYWLD 1935
            MYGL+LE + ++I S YGE+ W  I R A ID  +F  H+VY E L+  + + A + L ++  + M   G++F+ FV QYGYD +L VLGR +RDFLNGLDNLHEYL+FSYP+++ PSF C NE+K G+TL YR++R G+++Y  GQI E+AR FY  EM IE+V +    +  +   +L F+N+ F        + E  LP+ + V FE+FPF +VF   M   + G  ++  LP+L  + IT +F L RPLI F +  ++  TNNIFEL+ +DP      + +  +L+  + S  ++       SL+++GQM YM  W  I+FLGTP+M D+ S+   GL+INDLSMHD SRDL+LAG QQS ELKLAL+QE +KSKKLEES+  LDE M++TDELL+QMIPK VA+RLR G   +DTCE FD V+ILFSD+V FT ICS+I P +VV MLN +YS+FD+LTE++ VYKVETIGDAYM+ +G P     HA  + +M+LDM+ +I  L DPS   + L+IRVG+H+G VVAG+VGLKMPRYCLFGDTVNTASRMES S   K+HISE+TK  +    +YKI ERG ID+KGKG + TYWL+
Sbjct:    1 MYGLLLENLSEYIKSVYGEEKWEDIRRQAGIDSPSFSVHQVYPENLLQKLAKKAQQVLGVSERDFMDQMGVYFVGFVGQYGYDRVLSVLGRHMRDFLNGLDNLHEYLKFSYPRMRAPSFICENETKQGLTLHYRSKRRGFVYYTMGQIREVARYFYHKEMHIELVREEILFDTVHVTFQLTFDNRAFTLASLAMTREEKHLPISAHVLFEIFPFCMVFGADMVVRSIGNSLMVILPELLGKKITAWFDLVRPLIAFKFQTILNRTNNIFELVTVDPVTERFDVQNEDLLQHEDGSEPEK-------SLRLKGQMVYMENWRMIMFLGTPVMPDLTSLITTGLYINDLSMHDFSRDLMLAGTQQSVELKLALDQEQQKSKKLEESMRLLDEEMRRTDELLYQMIPKQVADRLRRGENPIDTCEMFDSVSILFSDIVTFTEICSRITPMEVVSMLNAMYSIFDKLTERNSVYKVETIGDAYMVVAGAPDKDANHAERVCDMALDMVDAITDLKDPST-GQHLRIRVGVHSGAVVAGIVGLKMPRYCLFGDTVNTASRMESTSIAMKVHISESTKVLIG--PNYKIIERGEIDVKGKGTMGTYWLE 593          

Query:  163 MYGLILEGVRQFICSKYGEDHWNSILRSADIDVITFGTHEVYGETLIPNIIESASRFLNMTVDEIMFLNGIFFINFVSQYGYDGILRVLGRDLRDFLNGLDNLHEYLRFSYPKLKPPSFFCVNESKTGITLQYRTRRSGYIHYVRGQITEIARQFYSTEMSIEIVSQTSEDNVSNCIMRLHFNNKNF-------IQIEDLLXXXXXXXXXXXXXNIVFNRGMRAINCGKGMLNALPDLPHQLITEYFLLTRPLIEFTWDAVMLHTNNIFELIHLDP-----KISSSKILREGNHSSKKRTLSRNNPSLKMRGQMKYMPEWDAIVFLGTPIMRDVESMYKAGLFINDLSMHDSSRDLVLAGXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMKKTDELLFQMIPKSVAERLRHGSEAVDTCEHFDEVTILFSDVVGFTTICSKINPFDVVEMLNKLYSVFDELTEKHKVYKVETIGDAYMIASGCPTVTQYHAPFIIEMSLDMIKSIGFLMDPSDHSRSLQIRVGIHTGMVVAGVVGLKMPRYCLFGDTVNTASRMESNSEPQKIHISEATKAKVTDLQSYKISERGHIDIKGKGNIKTYWLD 1935
            MYGL+LE + ++I S YGE+ W  I R A ID  +F  H+VY E L+  + + A + L ++  + M   G++F+ FV QYGYD +L VLGR +RDFLNGLDNLHEYL+FSYP+++ PSF C NE+K G+TL YR++R G+++Y  GQI E+AR FY  EM IE+V +    +  +   +L F+N+ F        + E  LP+ + V FE+FPF +VF   M   + G  ++  LP+L  + IT +F L RPLI F +  ++  TNNIFEL+ +DP      + +  +L+  + S  ++       SL+++GQM YM  W  I+FLGTP+M D+ S+   GL+INDLSMHD SRDL+LAG QQS ELKLAL+QE +KSKKLEES+  LDE M++TDELL+QMIPK VA+RLR G   +DTCE FD V+ILFSD+V FT ICS+I P +VV MLN +YS+FD+LTE++ VYKVETIGDAYM+ +G P     HA  + +M+LDM+ +I  L DPS   + L+IRVG+H+G VVAG+VGLKMPRYCLFGDTVNTASRMES S   K+HISE+TK  +    +YKI ERG ID+KGKG + TYWL+
Sbjct:    1 MYGLLLENLSEYIKSVYGEEKWEDIRRQAGIDSPSFSVHQVYPENLLQKLAKKAQQVLGVSERDFMDQMGVYFVGFVGQYGYDRVLSVLGRHMRDFLNGLDNLHEYLKFSYPRMRAPSFICENETKQGLTLHYRSKRRGFVYYTMGQIREVARYFYHKEMHIELVREEILFDTVHVTFQLTFDNRAFTLASLAMTREEKHLPISAHVLFEIFPFCMVFGADMVVRSIGNSLMVILPELLGKKITAWFDLVRPLIAFKFQTILNRTNNIFELVTVDPVTERFDVQNEDLLQHEDGSEPEK-------SLRLKGQMVYMENWRMIMFLGTPVMPDLTSLITTGLYINDLSMHDFSRDLMLAGTQQSVELKLALDQEQQKSKKLEESMRLLDEEMRRTDELLYQMIPKQVADRLRRGENPIDTCEMFDSVSILFSDIVTFTEICSRITPMEVVSMLNAMYSIFDKLTERNSVYKVETIGDAYMVVAGAPDKDANHAERVCDMALDMVDAITDLKDPST-GQHLRIRVGVHSGAVVAGIVGLKMPRYCLFGDTVNTASRMESTSIAMKVHISESTKVLIG--PNYKIIERGEIDVKGKGTMGTYWLE 593          

Query: 1303 KKTDELLFQMIPKSVAERLRHGSEAVDTCEHFDEVTILFSDVVGFTTICSKINPFDVVEMLNKLYSVFDELTEKHKVYKVETIGDAYMIASGCPTVT-QYHAPFIIEMSLDMIKSIGFLMDPSDHSRSLQIRVGIHTGMVVAGVVGLKMPRYCLFGDTVNTASRMESNSEPQKIHISEATKAKVTDLQSYKISERGHIDIKGKGNIKTYWLDGHNLENPKAVASLITQLE 1989
            KKTD LL+QM+P+ VAE L+ G      C  FD VTILFSD+VGFT +C+   PF+VVEMLN  Y+  D +   + VYKVETIGDAYM+ SG P      HA  I  ++L +++++G L      + ++Q+R+G+H+G   AGVVG KMPRYCLFGDTVNTASRMES  +  +IHISEAT   +  + SY   ERG   IKGKG+++TYWL     + P+    LI+ ++
Sbjct:  832 KKTDMLLYQMLPRPVAELLKRGDPVEAEC--FDCVTILFSDIVGFTELCTTSTPFEVVEMLNDWYTCCDSIISNYDVYKVETIGDAYMVVSGLPLQNGSRHAGEIASLALHLLETVGNLKIRHKPTETVQLRIGVHSGPCAAGVVGQKMPRYCLFGDTVNTASRMESTGDSMRIHISEATYQLLQVIGSYVCIERGLTSIKGKGDMRTYWLTKR--QQPELTPDLISTVD 1057          

Query: 1303 KKTDELLFQMIPKSVAERLRHGSEAVDTCEHFDEVTILFSDVVGFTTICSKINPFDVVEMLNKLYSVFDELTEKHKVYKVETIGDAYMIASGCPTVT-QYHAPFIIEMSLDMIKSIGFLMDPSDHSRSLQIRVGIHTGMVVAGVVGLKMPRYCLFGDTVNTASRMESNSEPQKIHISEATKAKVTDLQSYKISERGHIDIKGKGNIKTYWLDGHNLENPKAVASLITQLE 1989
            KKTD LL+QM+P+ VAE L+ G      C  FD VTILFSD+VGFT +C+   PF+VVEMLN  Y+  D +   + VYKVETIGDAYM+ SG P      HA  I  ++L +++++G L      + ++Q+R+G+H+G   AGVVG KMPRYCLFGDTVNTASRMES  +  +IHISEAT   +  + SY   ERG   IKGKG+++TYWL     + P+    LI+ ++
Sbjct:  868 KKTDMLLYQMLPRPVAELLKRGDPVEAEC--FDCVTILFSDIVGFTELCTTSTPFEVVEMLNDWYTCCDSIISNYDVYKVETIGDAYMVVSGLPLQNGSRHAGEIASLALHLLETVGNLKIRHKPTETVQLRIGVHSGPCAAGVVGQKMPRYCLFGDTVNTASRMESTGDSMRIHISEATYQLLQVIGSYVCIERGLTSIKGKGDMRTYWLTKR--QQPELTPDLISTVD 1093          

Query:  163 MYGLILEGVRQFICSKYGEDHWNSILRSADIDVI-TFGTHEVYGETLIPNIIESASRFLNMTVDEIMFLNGIFFINFVSQYGYDGILRVLGRDLRDFLNGLDNLHEYLRFSYPKLKPPSFFCVNESK-TGITLQYRTRRSGYIHYVRGQITEIARQFYSTEMSIEIVSQTSE--DNVSNCIMRLHFNNKNFIQIEDLLXXXXXXXX--------XXXXXNIVFNRGMRAINCGKGMLNALPDLPHQL--ITEYFLLTRPLIEFTWDAVMLHTNNIFELIHLDPKISSSKILREGNHSSKKRTLSRNNPSLKMRGQMKYMPEWDAIVFLGTPIMRDVESMYKAGLFINDLSMHDSSRDLVLAGXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMKKTDELLFQMIPKSVAERLRHGSEAVDTCEHFDEVTILFSDVVGFTTICSK----INPFDVVEMLNKLYSVFDELTEKHK---VYKVETIGDAYMIASGCPTVTQYHAPFIIEMSLDMIKSIGFLMDPSDHSRSLQIRVGIHTGMVVAGVVGLKMPRYCLFGDTVNTASRMESNSEPQKIHISEATKAKVTDLQS----YKISERGHIDIKGKGNIKTYWL 1932
            MYG +   +   +   YG D W  I R A +DV   F    +Y +    +++ +AS+ L M    I+ + G  F  F  + GYD ILRVLG ++R+FL  LD LH++L   YP ++ PSF C +  K   + L Y + R G    V G I  +A+Q + TE+ ++++   SE  D++   I       + F +  D                  + FPF+++F++ +    CG  +   LP L   +  ++  F L RP I+F++  ++ H N +F L       S   +L      ++          L+++GQM  +PE + I+FL +P + +++ + + GL+++D+ +HD++RDLVL GEQ   E KL  E E    +         DE  KKTD LL+ ++P SVA  LRH        + +D VTILFS +VGF   CSK         +V +LN +Y+ FD LT+  K   VYKVET+GD YM  SG P    +HA  I  ++LDM++  G +    D    +QI +GIHTG VV GV+G +MPRYCLFG+TVN  SR E+  E  KI++SE T   +  +++    + +  RG + +KGK      W 
Sbjct:    1 MYGFVNHALELLVLRNYGPDVWEDIKREAQVDVEGQFLVRIIYEDAKTYDLVAAASKVLKMDAGGILQMFGKMFFEFCQESGYDTILRVLGSNVREFLQNLDALHDHLGTIYPGMRAPSFRCTDAEKGNNLILHYYSEREGLQDIVIGIIKTVAQQIHGTEIEMKVIQPKSEECDHIKFLIEEKDSEEEAFYEDLDGFEENGTQETRISPYTFCKAFPFHLMFDKDLMLTQCGNAIFRVLPQLQPGVCNLSSVFSLVRPHIDFSFHGILSHINTVFVLR------SKEGLLNVETAENEDELTGTEISCLRLKGQMISLPETENILFLCSPSVMNLDDLTRRGLYLSDIPLHDATRDLVLLGEQFREEYKLTQELEILTDRLQHTLRALEDEK-KKTDRLLYSVLPPSVANELRHKRPV--PAKRYDNVTILFSGIVGFNAFCSKHASAEGAIKIVNLLNDIYTRFDILTDSRKNPYVYKVETVGDKYMTVSGLPEPCTHHAKSICHLALDMMEIAGQVKVDED---PVQITIGIHTGEVVTGVIGQRMPRYCLFGNTVNLTSRTETTGEKGKINVSEYTYRCLQSVENADPQFHLEYRGPVTMKGKKEPMKVWF 603          

Query:  196 FICSKYGEDHWNSILRSADIDVI-TFGTHEVYGETLIPNIIESASRFLNMTVDEIMFLNGIFFINFVSQYGYDGILRVLGRDLRDFLNGLDNLHEYLRFSYPKLKPPSFFCVNESK-TGITLQYRTRRSGYIHYVRGQITEIARQFYSTEMSIEIVSQTSE--DNVSNCIMRLHFNNKNFIQIEDLLXXXXXXXX--------XXXXXNIVFNRGMRAINCGKGMLNALPDLPHQL--ITEYFLLTRPLIEFTWDAVMLHTNNIFELIHLDPKISSSKILREGNHSSKKRTLSRNNPSLKMRGQMKYMPEWDAIVFLGTPIMRDVESMYKAGLFINDLSMHDSSRDLVLAGXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMKKTDELLFQMIPKSVAERLRHGSEAVDTCEHFDEVTILFSDVVGFTTICSK----INPFDVVEMLNKLYSVFDELTEKHK---VYKVETIGDAYMIASGCPTVTQYHAPFIIEMSLDMIKSIGFLMDPSDHSRSLQIRVGIHTGMVVAGVVGLKMPRYCLFGDTVNTASRMESNSEPQKIHISEATKAKVTDLQS----YKISERGHIDIKGKGNIKTYWL 1932
             +   YG D W  I R A +DV   F    +Y +    +++ +AS+ L M    I+ + G  F  F  + GYD ILRVLG ++R+FL  LD LH++L   YP ++ PSF C +  K   + L Y + R G    V G I  +A+Q + TE+ ++++   SE  D++   I       + F +  D                  + FPF+++F++ +    CG  +   LP L   +  ++  F L RP I+F++  ++ H N +F L       S   +L      ++          L+++GQM  +PE + I+FL +P + +++ + + GL+++D+ +HD++RDLVL GEQ   E KL  E E    +         DE  KKTD LL+ ++P SVA  LRH        + +D VTILFS +VGF   CSK         +V +LN +Y+ FD LT+  K   VYKVET+GD YM  SG P    +HA  I  ++LDM++  G +    D    +QI +GIHTG VV GV+G +MPRYCLFG+TVN  SR E+  E  KI++SE T   +  +++    + +  RG + +KGK      W 
Sbjct:    6 LVLRNYGPDVWEDIKREAQVDVEGQFLVRIIYEDAKTYDLVAAASKVLKMDAGGILQMFGKMFFEFCQESGYDTILRVLGSNVREFLQNLDALHDHLGTIYPGMRAPSFRCTDAEKGNNLILHYYSEREGLQDIVIGIIKTVAQQIHGTEIEMKVIQPKSEECDHIKFLIEEKDSEEEAFYEDLDGFEENGTQETRISPYTFCKAFPFHLMFDKDLMLTQCGNAIFRVLPQLQPGVCNLSSVFSLVRPHIDFSFHGILSHINTVFVLR------SKEGLLNVETAENEDELTGTEISCLRLKGQMISLPETENILFLCSPSVMNLDDLTRRGLYLSDIPLHDATRDLVLLGEQFREEYKLTQELEILTDRLQHTLRALEDEK-KKTDRLLYSVLPPSVANELRHKRPV--PAKRYDNVTILFSGIVGFNAFCSKHASAEGAIKIVNLLNDIYTRFDILTDSRKNPYVYKVETVGDKYMTVSGLPEPCTHHAKSICHLALDMMEIAGQVKVDED---PVQITIGIHTGEVVTGVIGQRMPRYCLFGNTVNLTSRTETTGEKGKINVSEYTYRCLQSVENADPQFHLEYRGPVTMKGKKEPMKVWF 597          

Query:  784 NIVFNRGMRAINCGKGMLNALPDLPHQLIT--EYFLLTRPLIEFTWDAVMLHTNNIFELIHLDPKISSSKILREGNHSSKKRTLSRNNPSLKMRGQMKYMPEWDAIVFLGTPIMRDVESMYKAGLFINDLSMHDSSRDLVLAGXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMKKTDELLFQMIPKSVAERLRHGSEAVDTCEHFDEVTILFSDVVGFTTICSKINPFDVVEMLNKLYSVFDELTEKHKVYKVETIGDAYMIASGCPTVTQYHAPFIIEMSLDMIKSIGFLMDPSDHSRSLQIRVGIHTGMVVAGVVGLKMPRYCLFGDTVNTASRMESNSEPQKIHISEATKAKVTDLQSYKISERGHIDIKGKGNIKTYWL 1932
            +IVF+  +   + G  +   +P L    I   EYF +  P + F   ++    N+ F L       +  ++L E         + +N P+LK+RGQM +M   + +++L +P +R ++ + + GL + D++ HD++RDL+L  +Q+ AE++L+ + E +K +    S +   E  +K+++LL+ M+P  VA +L+ G   V+  E F   TILFSDVV FT IC+   P  +V MLN +YS FD LT  H VYKVETIGDAYM+  G P  T  HA  +   +L M  +   + +P    + +QIRVG+HTG V+AGVVG KMPRYCLFGDTVNTASRMES+  P  IH+S  T + + D   ++++ERG I++KGKG ++TY+L
Sbjct:  276 HIVFDSDLVVKHTGVNIQKFVPGLQTAGIRLDEYFTIVHPEVIFNIQSIKKFINSQFVLK------TRREMLPE---------VQQNQPTLKLRGQMMWMESLNCMIYLCSPKLRSLQELEERGLHLADIAQHDTTRDLILLNQQRLAEIELSNQLERKKEELRILSRNLEIEK-QKSEKLLYAMLPTHVANQLKEGKR-VEAGE-FKVCTILFSDVVTFTNICAACEPIQIVNMLNAMYSRFDRLTSIHNVYKVETIGDAYMVVGGVPVPTNTHAERVANFALGMRIAAREVTNPIT-GQPIQIRVGLHTGPVLAGVVGEKMPRYCLFGDTVNTASRMESHGVPDHIHVSPFTFSVIKDKGIFEMAERGEIEVKGKGLMRTYFL 641          

Query:  163 MYGLILEGVRQFICSKYGEDHWNSILRSADIDVITFGTHEVYGETLIPNIIESASRFLNMTVDEIMFLNGIFFINFVSQYGYDGILRVLGRDLRDFLNGLDNLHEYLRFSYPKLKPPSFFCVNESKTGITLQYRTRRSGYIHYVRGQITEIARQFYSTEMSIEIVSQTSED 675
            MYG I   ++  +  ++GE+ W ++   A +   TF T+E+Y + +   +++ A + L+++ + ++ L G +F +F    GYD +LR LG +L +F+  LD LH YL  SY  +  PSF         I L Y + R G  H V G I  +A+ F+ +E+++ I++Q+ ED
Sbjct:    1 MYGFINTCLKSLVIERFGEETWENLRLMAGVQE-TFMTYEIYDDIITLRLVQEACKMLDVSSEVVLKLFGEYFFSFCKMSGYDTMLRTLGGNLVEFIENLDALHSYLALSYEAMNAPSFRVERMDDGRILLHYYSDRKGLYHIVPGIIEAVAKDFFDSEVTMTILNQSEED 170          

Query: 1303 KKTDELLFQMIPKSVAERLRHGSEAVDTCEHFDEVTILFSDVVGFTTICSKINPFDVVEMLNKLYSVFDELTEKHKVYKVETIGDAYMIASGCPTVT-QYHAPFIIEMSLDMIKSIGFLMDPSDHSRSLQIRVGIHTGMVVAGVVGLKMPRYCLFGDTVNTASRMESNSEPQKIHISEATKAKVTDLQSYKISERGHIDIKGKGNIKTYWLDG 1938
            +K + LL+Q++P SVAE+L+ G E V   E FD VTI FSD+VGFT++ ++  P  VV +LN LY+ FD + +   VYKVETIGDAYM+ SG P    + H   I  MSL +++++            L++R+GIH+G V AGVVGLKMPRYCLFGDTVNT+SRMESN EP KIH+S AT+A + +   +++  RG +++KGKG ++TYWL G
Sbjct:  601 RKAEALLYQILPHSVAEQLKRG-ETVQA-EAFDSVTIYFSDIVGFTSLSAESTPLQVVTLLNDLYTCFDAIIDNFDVYKVETIGDAYMVVSGLPVRNGKLHGREIARMSLALLEAVKTFKIRHRPDEQLKLRIGIHSGPVCAGVVGLKMPRYCLFGDTVNTSSRMESNGEPLKIHVSSATRAVLQEFNCFQLELRGDVEMKGKGKMRTYWLLG 811          

Query: 1330 MIPKSVAERLRHGSEAVDTCEHFDEVTILFSDVVGFTTICSKINPFDVVEMLNKLYSVFDELTEKHKVYKVETIGDAYMIASGCPTVTQ-YHAPFIIEMSLDMIKSIGFLMDPSDHSRSLQIRVGIHTGMVVAGVVGLKMPRYCLFGDTVNTASRMESNSEPQKIHISEATKAKVTDLQSYKISERGHIDIKGKGNIKTYWLDGHNLENPKAVASLITQLERER 1998
            M+PK VA+ LR G       + +   T+ FSD+VGFT + S   P+ VV+ LNKLY+ FDE+ + H VYKVETIGDAYM+ SG P      HA  I  M+LD++        P      LQIR GIH+G VVAGVVG KMPRYCLFGDTVNTASRMES SE  KI  S +    + ++  Y ++ RG + +KGKG++ TYWL+G   ++ K  A   TQ E E+
Sbjct:    1 MLPKQVADDLRLGKPM--QAQSYVSATVFFSDIVGFTQLSSTSTPYQVVDFLNKLYTTFDEIIDNHDVYKVETIGDAYMVVSGVPRENGILHASEIANMALDLVSVCKTFRIPHRPQTQLQIRAGIHSGPVVAGVVGTKMPRYCLFGDTVNTASRMESTSEALKIQCSSSAFYLLEEIGGYLLTCRGLLQVKGKGDMVTYWLEGKCSKDMKKPA---TQQESEK 219          

Query:  163 MYGLILEGVRQFICSKYGEDHWNSILRSADIDVI-TFGTHEVYGETLIPNIIESASRFLNMTVDEIMFLNGIFFINFVSQYGYDGILRVLGRDLRDFLNGLDNLHEYLRFSYPKLKPPSFFCVNESK-TGITLQYRTRRSGYIHYVRGQITEIARQFYSTEMSIEIVSQTSE--DNVSNCIMRLHFNNKNFIQIEDLLXXXXXXXX--------XXXXXNIVFNRGMRAINCGKGMLNALPDL-PHQL-ITEYFLLTRPLIEFTWDAVMLHTNNIFELIHLDPKISSSKILREGNHSSKKRTLSRNNPSLKMRGQMKYMPEWDAIVFLGTPIMRDVESMYKAGLFINDLSMHDSSRDLVLAGXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMKKTDELLFQMIPKSVAERLRHGSEAVDTCEHFDEVTILFSDVVGFTTICSK----INPFDVVEMLNKLYSVFDELTEKHK---VYKVETIGDAYMIASGCPTVTQYHAPFIIEMSLDMIKSIGFLMDPSDHSRSLQIRVGIHTGMVVAGVVGLKMPRYCLFGDTVNTASRMESNSEPQKIHISEAT-----KAKVTDLQSYKISERGHIDIKGKGNIKTYWL 1932
            MYG +   +   +   YG + W  I + A +D    F    +Y ++   +++ +A++ LN+   +I+ + G  F  F  + GYD ILRVLG ++R+FL  LD LH++L   YP ++ PSF C +  K  G+ L Y + R G    V G +  +A+Q + TE+ ++++ Q +E  D+    I       ++F + +D                  + FPF+I+F+R +    CG  +   LP L P    +   F L RP I+ ++  ++ H N +F L       S   +L      S+          L+++GQM Y+PE D I+FL +P + +++ + + GL+++D+ +HD++RDLVL GEQ   E KL  E E    +         DE  KKTD LL+ ++P SVA  LRH        + +D VTILFS +VGF T CSK         +V +LN +Y+ FD LT+      VYKVET+GD YM  SG P    +HA  I  ++LDM++  G +    +   S+QI +GIHTG VV GV+G +MPRYCLFG+TVN  SR E+  E  KI++SE T       + +D Q + +  RG + +KGK +    W 
Sbjct:    1 MYGFVNHALELLVIRNYGPEVWEDIKKEAQLDEEGQFLVRIIYDDSKTYDLVSAATKVLNLNAGDILQMFGNMFFVFCQESGYDTILRVLGSNVREFLQNLDALHDHLGTIYPGMRAPSFRCTDAEKGKGLILHYYSEREGLQDIVIGIVKTVAQQIHGTEIDMKVIQQRNEECDHTQFLIEEKDTREEDFYEDQDRFEENGTQESRISPYTFCKAFPFHIMFDRDLFVTQCGNAIYRVLPQLQPGNCNLLSVFSLVRPHIDISFHGILSHINTVFVL------RSKEGLLDVEKSESEDELTGTEISCLRLKGQMIYLPEADNILFLCSPSVMNLDDLTRRGLYLSDIPLHDATRDLVLLGEQFREEYKLTQELEILTDRLQHTLRALEDEK-KKTDTLLYSVLPPSVANELRHKRPV--PAKRYDNVTILFSGIVGFNTFCSKHASGEGAMKIVNLLNDIYTRFDILTDSRNNPYVYKVETVGDKYMTVSGIPEPCVHHARSICHLALDMMEIAGQVQVDGE---SVQITIGIHTGEVVTGVIGQRMPRYCLFGNTVNLTSRTETTGEKGKINVSEYTYRCLMSPENSDPQ-FHLQYRGPVSMKGKTDPMQVWF 603          

Query:  163 MYGLILEGVRQFICSKYGEDHWNSILRSADIDVI-TFGTHEVYGETLIPNIIESASRFLNMTVDEIMFLNGIFFINFVSQYGYDGILRVLGRDLRDFLNGLDNLHEYLRFSYPKLKPPSFFCVNESK-TGITLQYRTRRSGYIHYVRGQITEIARQFYSTEMSIEIVSQTSE--DNVSNCIMRLHFNNKNFIQIEDLLXXXXXXXX--------XXXXXNIVFNRGMRAINCGKGMLNALPDL-PHQL-ITEYFLLTRPLIEFTWDAVMLHTNNIFELIHLDPKISSSKILREGNHSSKKRTLSRNNPSLKMRGQMKYMPEWDAIVFLGTPIMRDVESMYKAGLFINDLSMHDSSRDLVLAGXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMKKTDELLFQMIPKSVAERLRHGSEAVDTCEHFDEVTILFSDVVGFTTICSK----INPFDVVEMLNKLYSVFDELTEKHK---VYKVETIGDAYMIASGCPTVTQYHAPFIIEMSLDMIKSIGFLMDPSDHSRSLQIRVGIHTGMVVAGVVGLKMPRYCLFGDTVNTASRMESNSEPQKIHISEAT-----KAKVTDLQSYKISERGHIDIKGKGNIKTYWL 1932
            MYG +   +   +   YG + W  I + A +D    F    +Y ++   +++ +A++ LN+   +I+ + G  F  F  + GYD ILRVLG ++R+FL  LD LH++L   YP ++ PSF C +  K  G+ L Y + R G    V G +  +A+Q + TE+ ++++ Q +E  D+    I       ++F + +D                  + FPF+I+F+R +    CG  +   LP L P    +   F L RP I+ ++  ++ H N +F L       S   +L      S+          L+++GQM Y+PE D I+FL +P + +++ + + GL+++D+ +HD++RDLVL GEQ   E KL  E E    +         DE  KKTD LL+ ++P SVA  LRH        + +D VTILFS +VGF T CSK         +V +LN +Y+ FD LT+      VYKVET+GD YM  SG P    +HA  I  ++LDM++  G +    +   S+QI +GIHTG VV GV+G +MPRYCLFG+TVN  SR E+  E  KI++SE T       + +D Q + +  RG + +KGK +    W 
Sbjct:    1 MYGFVNHALELLVIRNYGPEVWEDIKKEAQLDEEGQFLVRIIYDDSKTYDLVSAATKVLNLNAGDILQMFGNMFFVFCQESGYDTILRVLGSNVREFLQNLDALHDHLGTIYPGMRAPSFRCTDAEKGKGLILHYYSEREGLQDIVIGIVKTVAQQIHGTEIDMKVIQQRNEECDHTQFLIEEKDTREEDFYEDQDRFEENGTQESRISPYTFCKAFPFHIMFDRDLFVTQCGNAIYRVLPQLQPGNCNLLSVFSLVRPHIDISFHGILSHINTVFVL------RSKEGLLDVEKSESEDELTGTEISCLRLKGQMIYLPEADNILFLCSPSVMNLDDLTRRGLYLSDIPLHDATRDLVLLGEQFREEYKLTQELEILTDRLQHTLRALEDEK-KKTDTLLYSVLPPSVANELRHKRPV--PAKRYDNVTILFSGIVGFNTFCSKHASGEGAMKIVNLLNDIYTRFDILTDSRNNPYVYKVETVGDKYMTVSGIPEPCVHHARSICHLALDMMEIAGQVQVDGE---SVQITIGIHTGEVVTGVIGQRMPRYCLFGNTVNLTSRTETTGEKGKINVSEYTYRCLMSPENSDPQ-FHLQYRGPVSMKGKTDPMQVWF 603          

Query:  163 MYGLILEGVRQFICSKYGEDHWNSILRSADIDVI-TFGTHEVYGETLIPNIIESASRFLNMTVDEIMFLNGIFFINFVSQYGYDGILRVLGRDLRDFLNGLDNLHEYLRFSYPKLKPPSFFCVNESK-TGITLQYRTRRSGYIHYVRGQITEIARQFYSTEMSIEIVSQTSE--DNVSNCIMRLHFNNKNFIQIEDLLXXXXXXXX--------XXXXXNIVFNRGMRAINCGKGMLNALPDL-PHQL-ITEYFLLTRPLIEFTWDAVMLHTNNIFELIHLDPKISSSKILREGNHSSKKRTLSRNNPSLKMRGQMKYMPEWDAIVFLGTPIMRDVESMYKAGLFINDLSMHDSSRDLVLAGXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMKKTDELLFQMIPKSVAERLRHGSEAVDTCEHFDEVTILFSDVVGFTTICSK----INPFDVVEMLNKLYSVFDELTEKHK---VYKVETIGDAYMIASGCPTVTQYHAPFIIEMSLDMIKSIGFLMDPSDHSRSLQIRVGIHTGMVVAGVVGLKMPRYCLFGDTVNTASRMESNSEPQKIHISEAT-----KAKVTDLQSYKISERGHIDIKGKGNIKTYWL 1932
            MYG +   +   +   YG + W  I + A +D    F    +Y ++   +++ +A++ LN+   +I+ + G  F  F  + GYD ILRVLG ++R+FL  LD LH++L   YP ++ PSF C +  K  G+ L Y + R G    V G +  +A+Q + TE+ ++++ Q +E  D+    I       ++F + +D                  + FPF+I+F+R +    CG  +   LP L P    +   F L RP I+ ++  ++ H N +F L       S   +L      S+          L+++GQM Y+PE D I+FL +P + +++ + + GL+++D+ +HD++RDLVL GEQ   E KL  E E    +         DE  KKTD LL+ ++P SVA  LRH        + +D VTILFS +VGF T CSK         +V +LN +Y+ FD LT+      VYKVET+GD YM  SG P    +HA  I  ++LDM++  G +    +   S+QI +GIHTG VV GV+G +MPRYCLFG+TVN  SR E+  E  KI++SE T       + +D Q + +  RG + +KGK +    W 
Sbjct:    1 MYGFVNHALELLVIRNYGPEVWEDIKKEAQLDEEGQFLVRIIYDDSKTYDLVSAATKVLNLNAGDILQMFGNMFFVFCQESGYDTILRVLGSNVREFLQNLDALHDHLGTIYPGMRAPSFRCTDAEKGKGLILHYYSEREGLQDIVIGIVKTVAQQIHGTEIDMKVIQQRNEECDHTQFLIEEKDTREEDFYEDQDRFEENGTQESRISPYTFCKAFPFHIMFDRDLFVTQCGNAIYRVLPQLQPGNCNLLSVFSLVRPHIDISFHGILSHINTVFVL------RSKEGLLDVEKSESEDELTGTEISCLRLKGQMIYLPEADNILFLCSPSVMNLDDLTRRGLYLSDIPLHDATRDLVLLGEQFREEYKLTQELEILTDRLQHTLRALEDEK-KKTDTLLYSVLPPSVANELRHKRPV--PAKRYDNVTILFSGIVGFNTFCSKHASGEGAMKIVNLLNDIYTRFDILTDSRNNPYVYKVETVGDKYMTVSGIPEPCVHHARSICHLALDMMEIAGQVQVDGE---SVQITIGIHTGEVVTGVIGQRMPRYCLFGNTVNLTSRTETTGEKGKINVSEYTYRCLMSPENSDPQ-FHLQYRGPVSMKGKTDPMQVWF 603          

Query:  163 MYGLILEGVRQFICSKYGEDHWNSILRSADIDVI-TFGTHEVYGETLIPNIIESASRFLNMTVDEIMFLNGIFFINFVSQYGYDGILRVLGRDLRDFL------------------NGLDNLHEYLRFSYPKLKPPSFFCVNESK-TGITLQYRTRRSGYIHYVRGQITEIARQFYSTEMSIEIVSQTSE--DNVSNCIMRLHFNNKNFIQIEDLLXXXXXXXX--------XXXXXNIVFNRGMRAINCGKGMLNALPDL-PHQL-ITEYFLLTRPLIEFTWDAVMLHTNNIFELIHLDPKISSSKILREGNHSSKKRTLSRNNPSLKMRGQMKYMPEWDAIVFLGTPIMRDVESMYKAGLFINDLSMHDSSRDLVLAGXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMKKTDELLFQMIPKSVAERLRHGSEAVDTCEHFDEVTILFSDVVGFTTICSK----INPFDVVEMLNKLYSVFDELTEKHK---VYKVETIGDAYMIASGCPTVTQYHAPFIIEMSLDMIKSIGFLMDPSDHSRSLQIRVGIHTGMVVAGVVGLKMPRYCLFGDTVNTASRMESNSEPQKIHISEAT-----KAKVTDLQSYKISERGHIDIKGKGNIKTYWL 1932
            MYG +   +   +   YG + W  I + A +D    F    +Y ++   +++ +A++ LN+   +I+ + G  F  F  + GYD ILRVLG ++R+FL                  N LD LH++L   YP ++ PSF C +  K  G+ L Y + R G    V G +  +A+Q + TE+ ++++ Q +E  D+    I       ++F + +D                  + FPF+I+F+R +    CG  +   LP L P    +   F L RP I+ ++  ++ H N +F L       S   +L      S+          L+++GQM Y+PE D I+FL +P + +++ + + GL+++D+ +HD++RDLVL GEQ   E KL  E E    +         DE  KKTD LL+ ++P SVA  LRH        + +D VTILFS +VGF T CSK         +V +LN +Y+ FD LT+      VYKVET+GD YM  SG P    +HA  I  ++LDM++  G +    +   S+QI +GIHTG VV GV+G +MPRYCLFG+TVN  SR E+  E  KI++SE T       + +D Q + +  RG + +KGK +    W 
Sbjct:    1 MYGFVNHALELLVIRNYGPEVWEDIKKEAQLDEEGQFLVRIIYDDSKTYDLVSAATKVLNLNAGDILQMFGNMFFVFCQESGYDTILRVLGSNVREFLQHFIYIIDKKACFLLFPINNLDALHDHLGTIYPGMRAPSFRCTDAEKGKGLILHYYSEREGLQDIVIGIVKTVAQQIHGTEIDMKVIQQRNEECDHTQFLIEEKDTREEDFYEDQDRFEENGTQESRISPYTFCKAFPFHIMFDRDLFVTQCGNAIYRVLPQLQPGNCNLLSVFSLVRPHIDISFHGILSHINTVFVLR------SKEGLLDVEKSESEDELTGTEISCLRLKGQMIYLPEADNILFLCSPSVMNLDDLTRRGLYLSDIPLHDATRDLVLLGEQFREEYKLTQELEILTDRLQHTLRALEDEK-KKTDTLLYSVLPPSVANELRHKRPV--PAKRYDNVTILFSGIVGFNTFCSKHASGEGAMKIVNLLNDIYTRFDILTDSRNNPYVYKVETVGDKYMTVSGIPEPCVHHARSICHLALDMMEIAGQVQVDGE---SVQITIGIHTGEVVTGVIGQRMPRYCLFGNTVNLTSRTETTGEKGKINVSEYTYRCLMSPENSDPQ-FHLQYRGPVSMKGKTDPMQVWF 621          

Query:  163 MYGLILEGVRQFICSKYGEDHWNSILRSADIDVI-TFGTHEVYGETLIPNIIESASRFLNMTVDEIMFLNGIFFINFVSQYGYDGILRVLGRDLRDFLNGLDNLHEYLRFSYPKLKPPSFFCVNESKTGITLQYRTRRSGYIHYVRGQITEIARQFYSTEMSIEIVSQTSE--DNVSNCIMRLHFNNKNFIQIEDLLXXXXXXXX--------XXXXXNIVFNRGMRAINCGKGMLNALPDL-PHQL-ITEYFLLTRPLIEFTWDAVMLHTNNIFELIHLDPKISSSKILREGNHSSKKRTLSRNNPSLKMRGQMKYMPEWDAIVFLGTPIMRDVESMYKAGLFINDLSMHDSSRDLVLAGXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMKKTDELLFQMIPKSVAERLRHGSEAVDTCEHFDEVTILFSDVVGFTTICSK----INPFDVVEMLNKLYSVFDELTEKHK---VYKVETIGDAYMIASGCPTVTQYHAPFIIEMSLDMIKSIGFLMDPSDHSRSLQIRVGIHTGMVVAGVVGLKMPRYCLFGDTVNTASRMESNSEPQKIHISEAT-----KAKVTDLQSYKISERGHIDIKGKGNIKTYWL 1932
            MYG +   +   +   YG + W  I + A +D    F    +Y ++   +++ +A++ LN+   +I+ + G  F  F  + GYD ILRVLG ++R+FL               +++ P  F       G+ L Y + R G    V G +  +A+Q + TE+ ++++ Q +E  D+    I       ++F + +D                  + FPF+I+F+R +    CG  +   LP L P    +   F L RP I+ ++  ++ H N +F L       S   +L      S+          L+++GQM Y+PE D I+FL +P + +++ + + GL+++D+ +HD++RDLVL GEQ   E KL  E E    +         DE  KKTD LL+ ++P SVA  LRH        + +D VTILFS +VGF T CSK         +V +LN +Y+ FD LT+      VYKVET+GD YM  SG P    +HA  I  ++LDM++  G +    +   S+QI +GIHTG VV GV+G +MPRYCLFG+TVN  SR E+  E  KI++SE T       + +D Q + +  RG + +KGK +    W 
Sbjct:    1 MYGFVNHALELLVIRNYGPEVWEDIKKEAQLDEEGQFLVRIIYDDSKTYDLVSAATKVLNLNAGDILQMFGNMFFVFCQESGYDTILRVLGSNVREFL---------------QVRKPFIFYYCFKGKGLILHYYSEREGLQDIVIGIVKTVAQQIHGTEIDMKVIQQRNEECDHTQFLIEEKDTREEDFYEDQDRFEENGTQESRISPYTFCKAFPFHIMFDRDLFVTQCGNAIYRVLPQLQPGNCNLLSVFSLVRPHIDISFHGILSHINTVFVLR------SKEGLLDVEKSESEDELTGTEISCLRLKGQMIYLPEADNILFLCSPSVMNLDDLTRRGLYLSDIPLHDATRDLVLLGEQFREEYKLTQELEILTDRLQHTLRALEDEK-KKTDTLLYSVLPPSVANELRHKRPV--PAKRYDNVTILFSGIVGFNTFCSKHASGEGAMKIVNLLNDIYTRFDILTDSRNNPYVYKVETVGDKYMTVSGIPEPCVHHARSICHLALDMMEIAGQVQVDGE---SVQITIGIHTGEVVTGVIGQRMPRYCLFGNTVNLTSRTETTGEKGKINVSEYTYRCLMSPENSDPQ-FHLQYRGPVSMKGKTDPMQVWF 587          

Query:  163 MYGLILEGVRQFICSKYGEDHWNSILRSADIDVI-TFGTHEVYGETLIPNIIESASRFLNMTVDEIMFLNGIFFINFVSQYGYDGILRVLGRDLRDFLNGLDNLHEYLRFSYPKLKPPSFFCVNESK-TGITLQYRTRRSGYIHYVRGQITEIARQFYSTEMSIEIVSQTSE--DNVSNCIMRLHFNNKNFIQIEDLLXXXXXXXX--------XXXXXNIVFNRGMRAINCGKGMLNALPDL-PHQL-ITEYFLLTRPLIEFTWDAVMLHTNNIFELIHLDPKISSSKILREGNHSSKKRTLSRNNPSLKMRGQMKYMPEWDAIVFLGTPIMRDVESMYKAGLFINDLSMHDSSRDLVLAGXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMKKTDELLFQMIPKSVAERLRHGSEAVDTCEHFDEVTILFSDVVGFTTICSK----INPFDVVEMLNKLYSVFDELTEKHK---VYKVETIGDAYMIASGCPTVTQYHAPFIIEMSLDMIKSIGFLMDPSDHSRSLQIRVGIHTGMVVAGVVGLKMPRYCLFGDTVNTASRMESNSEPQKIHISEATKAKVTDLQS----YKISERGHIDIKGKGNIKTYWL 1932
            MYG +   +   +   YG + W  I + A +D    F    +Y ++   +++ +AS+ LN+   EI+ + G  F  F  + GYD ILRVLG ++R+FL  LD LH++L   YP ++ PSF C +  K  G+ L Y + R G    V G I  +A+Q + TE+ ++++ Q +E  D+    I       ++F +  D                  + FPF+I+F+R +    CG  +   LP L P    +   F L RP I+ ++  ++ H N +F L   +  +   K+  E   +  + +       L+++GQM Y+PE D+I+FL +P + +++ + + GL+++D+ +HD++RDLVL GEQ   E KL  E E    +         DE  KKTD LL+ ++P SVA  LRH        + +D VTILFS +VGF   CSK         +V +LN LY+ FD LT+  K   VYKVET+GD YM  SG P    +HA  I  ++LDM++  G +    +   S+QI +GIHTG VV GV+G +MPRYCLFG+TVN  SR E+  E  KI++SE T   +   ++    + +  RG + +KGK      W 
Sbjct:    1 MYGFVNHALELLVIRNYGPEVWEDIKKEAQLDEEGQFLVRIIYDDSKTYDLVAAASKVLNLNAGEILQMFGKMFFVFCQESGYDTILRVLGSNVREFLQNLDALHDHLATIYPGMRAPSFRCTDAEKGKGLILHYYSEREGLQDIVIGIIKTVAQQIHGTEIDMKVIQQRNEECDHTQFLIEEKESKEEDFYEDLDRFEENGTQESRISPYTFCKAFPFHIIFDRNLVVTQCGNAIYRVLPQLQPGNCSLLSVFSLVRPHIDISFHGILSHINTVFVLRSKEGLLDVEKLECEDELTGAEIS------CLRLKGQMIYLPEADSILFLCSPSVMNLDDLTRRGLYLSDIPLHDATRDLVLLGEQFREEYKLTQELEILTDRLQLTLRALEDEK-KKTDTLLYSVLPPSVANELRHKRPV--PAKRYDNVTILFSGIVGFNAFCSKHASGEGAMKIVNLLNDLYTRFDTLTDSRKNPFVYKVETVGDKYMTVSGLPEPCIHHARSICHLALDMMEIAGQVQVDGE---SVQITIGIHTGEVVTGVIGQRMPRYCLFGNTVNLTSRTETTGEKGKINVSEYTYRCLMSPENSDPLFHLEHRGPVSMKGKKEPMQVWF 603          

Query:  163 MYGLILEGVRQFICSKYGEDHWNSILRSADIDVI-TFGTHEVYGETLIPNIIESASRFLNMTVDEIMFLNGIFFINFVSQYGYDGILRVLGRDLRDFLNGLDNLHEYLRFSYPKLKPPSFFCVNESK-TGITLQYRTRRSGYIHYVRGQITEIARQFYSTEMSIEIVSQTSE--DNVSNCIMRLHFNNKNFIQIEDLLXXXXXXXX--------XXXXXNIVFNRGMRAINCGKGMLNALPDL-PHQL-ITEYFLLTRPLIEFTWDAVMLHTNNIFELIHLDPKISSSKILREGNHSSKKRTLSRNNPSLKMRGQMKYMPEWDAIVFLGTPIMRDVESMYKAGLFINDLSMHDSSRDLVLAGXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMKKTDELLFQMIPKSVAERLRHGSEAVDTCEHFDEVTILFSDVVGFTTICSK----INPFDVVEMLNKLYSVFDELTEKHK---VYKVETIGDAYMIASGCPTVTQYHAPFIIEMSLDMIKSIGFLMDPSDHSRSLQIRVGIHTGMVVAGVVGLKMPRYCLFGDTVNTASRMESNSEPQKIHISEATKAKV 1851
            MYG +   +   +   YG + W  I + A +D    F    +Y ++   +++ +AS+ LN+   EI+ + G  F  F  + GYD ILRVLG ++R+FL  LD LH++L   YP ++ PSF C +  K  G+ L Y + R G    V G I  +A+Q + TE+ ++++ Q +E  D+    I       ++F +  D                  + FPF+I+F+R +    CG  +   LP L P    +   F L RP I+ ++  ++ H N +F L   +  +   K+  E   +  + +       L+++GQM Y+PE D+I+FL +P + +++ + + GL+++D+ +HD++RDLVL GEQ   E KL  E E    +         DE  KKTD LL+ ++P SVA  LRH        + +D VTILFS +VGF   CSK         +V +LN LY+ FD LT+  K   VYKVET+GD YM  SG P    +HA  I  ++LDM++  G +    +   S+QI +GIHTG VV GV+G +MPRYCLFG+TVN  SR E+  E  KI++SE T  K+
Sbjct:    1 MYGFVNHALELLVIRNYGPEVWEDIKKEAQLDEEGQFLVRIIYDDSKTYDLVAAASKVLNLNAGEILQMFGKMFFVFCQESGYDTILRVLGSNVREFLQNLDALHDHLATIYPGMRAPSFRCTDAEKGKGLILHYYSEREGLQDIVIGIIKTVAQQIHGTEIDMKVIQQRNEECDHTQFLIEEKESKEEDFYEDLDRFEENGTQESRISPYTFCKAFPFHIIFDRNLVVTQCGNAIYRVLPQLQPGNCSLLSVFSLVRPHIDISFHGILSHINTVFVLRSKEGLLDVEKLECEDELTGAEIS------CLRLKGQMIYLPEADSILFLCSPSVMNLDDLTRRGLYLSDIPLHDATRDLVLLGEQFREEYKLTQELEILTDRLQLTLRALEDEK-KKTDTLLYSVLPPSVANELRHKRPV--PAKRYDNVTILFSGIVGFNAFCSKHASGEGAMKIVNLLNDLYTRFDTLTDSRKNPFVYKVETVGDKYMTVSGLPEPCIHHARSICHLALDMMEIAGQVQVDGE---SVQITIGIHTGEVVTGVIGQRMPRYCLFGNTVNLTSRTETTGEKGKINVSEYTYRKL 572          

Query:  784 NIVFNRGMRAINCGKGMLNALPDLPHQL--ITEYFLLTRPLIEFTWDAVMLHTNNIFELIHLDPKISSSKILREGNHSSKKRTLSRNNPSLKMRGQMKYMPEWDAIVFLGTPIMRDVESMYKAGLFINDLSMHDSSRDLVLAGXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMKKTDELLFQMIPKSVAERLRHGSEAVDTCEHFDEVTILFSDVVGFTTICSKINPFDVVEMLNKLYSVFDELTEKHKVYKVETIGDAYMIASGCPTVTQYHAPFIIEMSLDMIKSIGFLMDPSDHSRSLQIRVGIHTGMVVAGVVGLKMPRYCLFGDTVNTASRMESNSEPQKIHISEATKAKVTDLQSYKISERGHIDIKGKGNIKTYWL 1932
            ++VF+  +R    G  +   +P +  Q   + EYF +  P + F   ++    N+ F L          K  RE    + K     + P+LK+RGQM +M     +VF+ +P +R ++ + ++ + ++D++ HD++RDL+L  +Q+ AE++L+ + E +K +    S H   E  KKT+ LL+ M+P+ VA +L+ G +       F+  TILFSDVV FT IC+   P  +V MLN +YS FD LT  H VYKVETIGDAYM+  G P   + HA  +   +L M  S   +M+P      +QIRVGIHTG V+AGVVG KMPRYCLFGDTVNTASRMES+  P K+H+S  T  +  + + ++I  RG I++KGKG + TY+L
Sbjct:  357 HVVFDEALRVKQAGVNIQKYVPGILTQKFGLDEYFSIVHPQVTFNISSICKFINSQFIL----------KTRREMMPEAWK-----SQPTLKLRGQMIWMESLKCMVFMCSPKLRSLQELEESKMHLSDIAPHDTTRDLILLNQQRLAEMELSCQLEKKKEELRVLSNHLAIEK-KKTETLLYAMLPEHVANQLKEGKKVA--AGEFETCTILFSDVVTFTNICAACEPIQIVNMLNSMYSKFDRLTNIHDVYKVETIGDAYMVVGGVPVPVESHAQRVANFALGMRISAKEVMNPVT-GEPIQIRVGIHTGPVLAGVVGDKMPRYCLFGDTVNTASRMESHGLPNKVHLS-PTAHRALENKGFEIVTRGEIEVKGKGKMTTYFL 721          

Query:  163 MYGLILEGVRQFICSKYGEDHWNSILRSADIDVITFGTHEVYGETLIPNIIESASRFLNMTVDEIMFLNGIFFINFVSQYGYDGILRVLGRDLRDFLNGLDNLHEYLRFSYPKLKPPSFFCVNESKTGITLQYRTRRSGYIHYVRGQITEIARQFYSTEMSIEIVSQTSE 672
            MYG I   ++  +  K+GE+ W  +  SA++  + F T+ VY +T+   +I+ A + L+++++ I+ L G +F  F    GYD +LR LG +L +F+  LD LH YL  SY ++  PSF     +   + L Y + R G  H V G I  +A+ F+ T++++ I+    E
Sbjct:   82 MYGFINTCLQSLVTEKFGEETWEKLKASAEVQDV-FMTYTVYDDTITVKLIQEACKALDVSMEAILKLFGEYFFKFCKMSGYDRMLRTLGGNLTEFIENLDALHSYLALSYQEMNAPSFRVEGGADGAMRLHYYSDRRGLCHIVPGIIEAVAKDFFDTDVAMSILDMNEE 250          

Query:  784 NIVFNRGMRAINCGKGMLNALPDLPHQL--ITEYFLLTRPLIEFTWDAVMLHTNNIFELIHLDPKISSSKILREGNHSSKKRTLSRNNPSLKMRGQMKYMPEWDAIVFLGTPIMRDVESMYKAGLFINDLSMHDSSRDLVLAGXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMKKTDELLFQMIPKSVAERLRHGSEAVDTCEHFDEVTILFSDVVGFTTICSKINPFDVVEMLNKLYSVFDELTEKHKVYKVETIGDAYMIASGCPTVTQYHAPFIIEMSLDMIKSIGFLMDPSDHSRSLQIRVGIHTGMVVAGVVGLKMPRYCLFGDTVNTASRMESNSEPQKIHISEATKAKVTDLQSYKISERGHIDIKGKGNIKTYWL 1932
            ++VF+  +R    G  +   +P +  Q   + EYF +  P + F   ++    N+ F L          K  RE    + K     + P+LK+RGQM +M     +VF+ +P +R ++ + ++ + ++D++ HD++RDL+L  +Q+ AE++L+ + E +K +    S H   E  KKT+ LL+ M+P+ VA +L+ G +       F+  TILFSDVV FT IC+   P  +V MLN +YS FD LT  H VYKVETIGDAYM+  G P   + HA  +   +L M  S   +M+P      +QIRVGIHTG V+AGVVG KMPRYCLFGDTVNTASRMES+  P K+H+S  T  +  + + ++I  RG I++KGKG + TY+L
Sbjct:  342 HVVFDEALRVKQAGVNIQKYVPGILTQKFGLDEYFSIVHPQVTFNISSICKFINSQFIL----------KTRREMMPEAWK-----SQPTLKLRGQMIWMESLKCMVFMCSPKLRSLQELEESKMHLSDIAPHDTTRDLILLNQQRLAEMELSCQLEKKKEELRVLSNHLAIEK-KKTETLLYAMLPEHVANQLKEGKKVA--AGEFETCTILFSDVVTFTNICAACEPIQIVNMLNSMYSKFDRLTNIHDVYKVETIGDAYMVVGGVPVPVESHAQRVANFALGMRISAKEVMNPVT-GEPIQIRVGIHTGPVLAGVVGDKMPRYCLFGDTVNTASRMESHGLPNKVHLS-PTAHRALENKGFEIVTRGEIEVKGKGKMTTYFL 706          

Query:  163 MYGLILEGVRQFICSKYGEDHWNSILRSADIDVITFGTHEVYGETLIPNIIESASRFLNMTVDEIMFLNGIFFINFVSQYGYDGILRVLGRDLRDFLNGLDNLHEYLRFSYPKLKPPSFFCVNESKTGITLQYRTRRSGYIHYVRGQITEIARQFYSTEMSIEIVSQTSE 672
            MYG I   ++  +  K+GE+ W  +  SA++  + F T+ VY +T+   +I+ A + L+++++ I+ L G +F  F    GYD +LR LG +L +F+  LD LH YL  SY ++  PSF     +   + L Y + R G  H V G I  +A+ F+ T++++ I+    E
Sbjct:   82 MYGFINTCLQSLVTEKFGEETWEKLKASAEVQDV-FMTYTVYDDTITVKLIQEACKALDVSMEAILKLFGEYFFKFCKMSGYDRMLRTLGGNLTEFIENLDALHSYLALSYQEMNAPSFRVEGGADGAMRLHYYSDRRGLCHIVPGIIEAVAKDFFDTDVAMSILDMNEE 250          

Query:  301 IPNIIESASRFLNMTVDEIM--FLNGIFFINFVSQYGYDGILRVLGRDLRDFLNGLDNLHEYLRFSYPK---LKPPSFFCVNESKTGITLQYRTRRSGYIHYVRGQITEIARQFYSTEMSIEIVSQTS----EDNVSNCIMRLHF-------------NNKNFIQIEDLLXXXXXXXXXXXXXNIVFNRGMRAINCGKGMLNALPDLPHQLIT--EYFLLTRPLIEFTWDAVMLHTNNIFELIHLDPKISSSKILREGNHSSKKRTLSRNNPSLKMRGQMKYMPEWDAIVFLGTPIMRDVESMYKAGLFINDLSMHDSSRDLVLAGXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMKKTDELLFQMIPKSVAERLRHGSEAVDTCEHFDEVTILFSDVVGFTTICSKINPFDVVEMLNKLYSVFDELTEKHKVYKVETIGDAYMIASGCPTVTQYHAPFIIEMSLDMIKSIGFLMDPSDHSRSLQIRVGIHTGMVVAGVVGLKMPRYCLFGDTVNTASRMESNSEPQKIHISEAT 1839
            +  I++  +  L +   EI   F    F I F      + +LR +G  L+DF NG D L E++R S+ K   L+  SF C    +  + L Y          + G I    ++ Y   + +E +          N SNC   L F             N +   Q+   L +    F   FPF+++F+  M  +  G+G+   L    H+ +   + F +  P+I  T+D V+L  +  F +I   P+ S ++                 +  ++++GQM ++PE  AI+FLG+P +  ++ +   GL ++D+ +HD++RD++L GEQ  A+  L    +  K+          +E  KKT +LL+ + P  VA++L            FD+VT+LFSD+VGFT IC++  P  V+ MLN+LY+ FD       +YKVETIGDAY +ASG    +  HA  I  M+L M++    ++ P    +++Q+R+GIH+G V+AGVVG++MPRYCLFG+ V  AS+ ES S P++I++S  T
Sbjct:  149 VSGILQCTANVLGLQFQEIQERFGEEFFKICFDEN---ERVLRAVGSTLQDFFNGFDALLEHIRTSFGKQATLESSSFLCKELPEGTLMLHYFHPHHTVGFAMLGMIKAAGKRIYHLNVEVEQIENEKLCFDGSNPSNCSC-LTFLIKECETTQITKDNPQGTSQVPADLRISINTFCRAFPFHLMFDSNMVVLQLGEGLRKQLRYDTHRALKFEDCFEIVSPMINATFDRVLLRLSTPF-VIRTKPEASGTE---------------NEDKVMEIKGQMIHVPESSAILFLGSPCVDKLDELMGRGLHLSDIPIHDATRDVILVGEQAKAQDGLKKRMDKLKATLERTHQALEEEK-KKTVDLLYSIFPGDVAQQLW--QGQQVQARKFDDVTMLFSDIVGFTAICAQCTPMQVISMLNELYTRFDHQCGLLDIYKVETIGDAYCVASGLHRKSLCHAKPIALMALKMMELSEEVLTPD--GKAIQMRIGIHSGSVLAGVVGVRMPRYCLFGNNVTLASKFESGSHPRRINVSPTT 660          

Query:  163 MYGLILEGVRQFICSKYGEDHWNSILRSADIDVITFGTHEVYGETLIPNIIESASRFLNMTVDEIMFLNGIFFINFVSQYGYDGILRVLGRDLRDFLNGLDNLHEYLRFSYPKLKPPSFFCVNESKTGITLQYRTRRSGYIHYVRGQITEIARQFYSTEMSIEIVSQTSEDNVSNCIMRLHFNNKNF-------IQIEDLLXXXXXXXXXXXXXNIVFNRGMRAINCGKGMLNALPDLPHQLITEYFLLTRPLIEFTWDAVMLHTNNIFELIHLDP-----KISSSKILREGNHSSKKRTLSRNNPSLKMRGQMKYMPEWDAIVFLGTPIMRDVESMYKAGLFINDLSMHDSSRDLVLAGXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMKKTDELLFQMIPKSVAERLRHGSEAVDTCEHFDEVTILFSDVVGFTTICSKINPFDVVEMLNKLYSVFDELTEKHKVYKVETIGDAYMIASGCPTVTQYHAPFIIEMSLDMIKSIGFLMDPSDHSRSLQIRVGIHTGMVVAGVVGLKMPRYCLFGDTVNTASRMESNSEPQKIHISEATKAKVTDLQSYKISERGHIDIKGKGNIKTYWLD 1935
            MYGL+LE + ++I S YGE+ W  I R A ID  +F  H+VY E L+  + + A + L ++  + M   G++F+ FV QYGYD +L VLGR +RDFLNGLDNLHEYL+FSYP+++ PSF C NE+K G+TL YR++R G+++Y  GQI E+AR FY  EM IE+V +    +  +   +L F+N+ F        + E  LP+ + V FE+FPF +VF   M   + G  ++  LP+L  + IT +F L RPLI F +  ++  TNNIFEL+ +DP      + +  +L+  + S  ++       SL+++GQM YM  W  I+FLGTP+M D+ S+   GL+INDLSMHD SRDL+LAG QQS ELKLAL+QE +KSKKLEES+  LDE M++TDELL+QMIPK VA+RLR G   +DTCE FD V+ILFSD+V FT ICS+I P +VV MLN +YS+FD+LTE++ VYKVETIGDAYM+ +G P     HA  + +M+LDM+ +I  L DPS   + L+IRVG+H+G VVAG+VGLKMPRYCLFGDTVNTASRMES S   K+HISE+TK  +    +YKI ERG ID+KGKG + TYWL+
Sbjct:    1 MYGLLLENLSEYIKSVYGEEKWEDIRRQAGIDSPSFSVHQVYPENLLQKLAKKAQQVLGVSERDFMDQMGVYFVGFVGQYGYDRVLSVLGRHMRDFLNGLDNLHEYLKFSYPRMRAPSFICENETKQGLTLHYRSKRRGFVYYTMGQIREVARYFYHKEMHIELVREEILFDTVHVTFQLTFDNRAFTLASLAMTREEKHLPISAHVLFEIFPFCMVFGADMVVRSIGNSLMVILPELLGKKITAWFDLVRPLIAFKFQTILNRTNNIFELVTVDPVTERFDVQNEDLLQHEDGSEPEK-------SLRLKGQMVYMENWRMIMFLGTPVMPDLTSLITTGLYINDLSMHDFSRDLMLAGTQQSVELKLALDQEQQKSKKLEESMRLLDEEMRRTDELLYQMIPKQVADRLRRGENPIDTCEMFDSVSILFSDIVTFTEICSRITPMEVVSMLNAMYSIFDKLTERNSVYKVETIGDAYMVVAGAPDKDANHAERVCDMALDMVDAITDLKDPST-GQHLRIRVGVHSGAVVAGIVGLKMPRYCLFGDTVNTASRMESTSIAMKVHISESTKVLIG--PNYKIIERGEIDVKGKGTMGTYWLE 593          

Query:  163 MYGLILEGVRQFICSKYGEDHWNSILRSADIDVITFGTHEVYGETLIPNIIESASRFLNMTVDEIMFLNGIFFINFVSQYGYDGILRVLGRDLRDFLNGLDNLHEYLRFSYPKLKPPSFFCVNESKTGITLQYRTRRSGYIHYVRGQITEIARQFYSTEMSIEIVSQTSEDNVSNCIMRLHFNNKNFIQ-----------IEDLLXXXXXXXXXXXXXNIVFNRGMRAINCGKGMLNALPDLPHQLITEYFLLTRPLIEFTWDAVMLHTNNIFELIHLDP-KISSSKILREGNHSSKKRTLSRNNPS-------LKMRGQMKYMPEWDAIVFLGTPIMRDVESMYKAGLFINDLSMHDSSRDLVLAGXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMKKTDELLFQMIPKSVAERLRHGSEAVDTCEHFDEVTILFSDVVGFTTICSKINPFDVVEMLNKLYSVFDELTEKHKVYKVETIGDAYMIASGCPTVTQYHAPFIIEMSLDMIKSIGFLMDPSDHSRSLQIRVGIHTGMVVAGVVGLKMPRYCLFGDTVNTASRMESNSEPQKIHISEATKAKV--TDLQSYKISERGHIDIKGKGNIKTYWL----DGHNLENPKAVAS 1971
            MYGLI++ +  +I  KYGE  W+ +   + +   TF   + + E L   +I +        VDE+M   G  F  F++++ ++ +LRVLGR    FLNGLDNLHEYLRF++PKLKPPSF+C +ES+TG+TL YR++R G++HYV+GQI  I+++ + TE+ IE++    + N+ + IMRLHFNN +F +           I + + + S++FF++FPF IVFNRGMR  N G G+L  +  +  + I + FLL RP I F W+ +MLH+NNIFELI  DP +     IL        + T  R+          L ++GQM YM EW++I F+G P+M  +  MYK+GLFIND ++HDSSRDLVLA  QQSAELKL L QE++KS+ + E++++L +  ++TD+LL+QM+PKSVA +LRHG  AV  CE FD VTILF+D+V FT +CS + P +V+E L  +Y+ FD++ + H VYKVETIGDAYM+ SG PT T++ A FI++ +   +   G +++ ++    + IR G+H+G VVAGVVGL MPRYCLFG+TV  A++ME NS P KI +SE T  K+  +D   Y+   R  I+IK    I+T+++      H + +P+   S
Sbjct:    1 MYGLIIDHIATYIKEKYGESTWSEVKFVSGVTDDTFQMDKKFSEGLSHKLIWACHDVTGDPVDELMTNIGTSFYKFLTKFEFNKVLRVLGRTFPQFLNGLDNLHEYLRFTFPKLKPPSFYCEHESRTGLTLHYRSKRRGFLHYVQGQIRNISQELFQTEVVIELLDIEHDLNLEHVIMRLHFNNLDFNRQGTAYRNLNDSILEKVKITSDIFFDIFPFIIVFNRGMRIRNIGIGLLRVMAGIVGKKINQTFLLMRPFIRFRWEEIMLHSNNIFELISSDPIQEDEDGILVYKTTDVDQMTEERHRMGDGEREKFLSLKGQMFYMEEWESICFVGIPVMSHLPQMYKSGLFINDFALHDSSRDLVLASTQQSAELKLLLHQEAQKSRNMRENMNRLKKERRRTDKLLYQMLPKSVANQLRHGESAVACCERFDSVTILFTDIVEFTKMCSSLTPLEVIEFLKVIYTNFDKIIDTHGVYKVETIGDAYMVVSGAPTKTEHDAEFILDCASQFLVEAGKMVNMNNKIHKIDIRAGVHSGSVVAGVVGLSMPRYCLFGETVYVANKMEQNSSPMKILVSETTHNKIEESDPGLYQFERREEIEIKDDQTIQTFFVVSRHGPHRVPSPRNCES 628          

Query:  163 MYGLILEGVRQFICSKYGEDHWNSILRSADIDVITFGTHEVYGETLIPNIIESASRFLNMTVDEIMFLNGIFFINFVSQYGYDGILRVLGRDLRDFLNGLDNLHEYLRFSYPKLKPPSFFCVNESKTGITLQYRTRRSGYIHYVRGQITEIARQFYSTEMSIEIVSQTSEDNVSNCIMRLHFNNKNFIQ----------IEDLLXXXXXXXXXXXXXNIVFNRGMRAINCGKGMLNALPDLPHQLITEYFLLTRPLIEFTWDAVMLHTNNIFELIHLDPKISSSK--------ILREGNHSSKKRTLSRNN----PSLKMRGQMKYMPEWDAIVFLGTPIMRDVESMYKAGLFINDLSMHDSSRDLVLAGXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMKKTDELLFQMIPKSVAER-LRHGSEAVDTCEHFDEVTILFSDVVGFTTICSKINPFDVVEMLNKLYSVFDELTEKHKVYKVETIGDAYMIASGCPTVTQYHAPFIIEMSLDMIKSI-GFLMDPSDHSRSLQIRVGIHTGMVVAGVVGLKMPRYCLFGDTVNTASRME-SNSEPQKIHISEATKAKVTDLQS--YKISERGHIDIKGKGNIKTYWLD 1935
            MYGL++EGVR  I   +G      + +   +   +  TH+ Y E ++P + ++         ++I  L G FF+ F+ + GY  ++ V+GR   DF+ GLDN+HEY RFSYPKL+ PSF+C +ES+ G+ L YR+RR+GY+ YV GQ+ E+AR FY  ++ I+++ +  +   +  ++++ F+N    Q          + + LPV ++ F ++FPF+I FN+ +  +  G+G+LN +P++   L+T+ F L RP I+FT + +M+H N +F++  L P +  ++         + E   S +K+T+  N     P + +RG +  +   +  + L T ++  +++M+K GL++ND    D +R++++A  Q+S  LK  LE E  +S+ L E   ++ E  K    LL QM+P  VA+  +R GS  VD CE F+ V+I F  V  F+ I   I  F+VV +LN +YS  D + + H VYKVETIG++YMI++GCP    Y A  + +  L+M+  I  F     D  + + I+ GI TG VV GVVG++ PRYCLFGDTVNTASRME SN  P  I I + TK +V    S  ++I  +G++ +KGKG+++ Y ++
Sbjct:    1 MYGLVIEGVRFMIQENWGPQVLLQVQKLTSLSEKSVSTHDQYSEHVVPQMFKAIHEITGTPYEQIGVLAGRFFVQFLIRNGYGDLMNVMGRRFSDFIKGLDNIHEYFRFSYPKLRAPSFYCKSESEDGLILHYRSRRTGYLSYVIGQLVELARVFYQLDIGIQVLKKKEKGRFTFVVLKISFDNVGLGQDLKLKERVKNLNEYLPVDTKSFLQMFPFHIAFNKKLEILMAGQGLLNLMPNIQGLLMTDVFDLQRPCIKFTAEGIMVHQNCVFQIESLHPVVKQTEENITVQINDITEDKVSLEKKTVMDNEYESLPYVTLRGPITVLKSSETFLLLATCVVDTLDTMFKMGLYLNDFGESDCNREIIMATIQKSDTLKTMLENEKRRSEVLTEMTREISEAKKTARTLLTQMMPYEVAQTMMRSGS--VDHCEAFECVSIGFIRVCDFSKISLFIEAFEVVNLLNTIYSHLDSIVDTHGVYKVETIGESYMISAGCPYRDDYDAEMVSDCCLEMVSHIKSFEYQSHDAVKKVLIKCGIFTGPVVGGVVGVRTPRYCLFGDTVNTASRMESSNQTPMTIQIGQRTKDRVEKQASGAFRIKPKGNVFVKGKGDMRVYEIE 616          

Query:  163 MYGLILEGVRQFICSKYGEDHWNSILRSADIDVI-TFGTHEVYGETLIPNIIESASRFLNMTVDEIMFLNGIFFINFVSQYGYDGILRVLGRDLRDFLNGLDNLHEYLRFSYPKLKPPSFFCVNESK-TGITLQYRTRRSGYIHYVRGQITEIARQFYSTEMSIEIVSQTSE--DNVSNCIMRLHFNNKNFIQIEDLLXXXXXXXXXXXXX--------NIVFNRGMRAINCGKGMLNALPDL-PHQL-ITEYFLLTRPLIEFTWDAVMLHTNNIFELIHLDPKISSSKILREGNHSSKKRTLSRNNPSLKMRGQMKYMPEWDAIVFLGTPIMRDVESMYKAGLFINDLSMHDSSRDLVLAGXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMKKTDELLFQMIPKSVAERLRHGSEAVDTCEHFDEVTILFSDVVGFTTICSK----INPFDVVEMLNKLYSVFDELTEKHK---VYKVETIGDAYMIASGCPTVTQYHAPFIIEMSLDMIKSIGFLMDPSDHSRSLQIRVGIHTGMVVAGVVGLKMPRYCLFGDTVNTASRMESNSEPQKIHISEAT-----KAKVTDLQSYKISERGHIDIKGKGNIKTYWL 1932
            MYG +   +   +   YG + W  I + A +D    F    +Y ++   +++ +AS+ LN+   EI+ + G  F  F  + GYD ILRVLG ++R+FL  LD LH++L   YP ++ PSF C +  K  G+ L Y + R G    V G I  +A+Q + TE+ ++++ Q SE  D+    I       ++F +  D           + P+        +I+F+R +    CG  +   LP L P +  +   F L RP I+ ++  ++ H N +F L   +  +   K+  E   +  + +       L+++GQM Y+PE D+I+FL +P + +++ + + GL+++D+ +HD++RDLVL GEQ   E KL  E E    +         DE  KKTD LL+ ++P SVA  LRH        + +D VTILFS +VGF   CSK         +V +LN LY+ FD LT+  K   VYKVET+GD YM  SG P    +HA  I  ++LDM++  G +    +   S+QI +GIHTG VV GV+G +MPRYCLFG+TVN  SR E+  E  KI++SE T       + +D Q + +  RG + +KGK      W 
Sbjct:    1 MYGFVNHALELLVIRNYGPEVWEDIKKEAQLDEEGQFLVRIIYDDSKTYDLVAAASKVLNLNAGEILQMFGKMFFVFCQESGYDTILRVLGSNVREFLQNLDALHDHLATIYPGMRAPSFRCTDAEKGKGLILHYYSEREGLQDIVIGIIKTVAQQIHGTEIDMKVIQQRSEECDHTQFLIEEKESKEEDFYEDLDRFEENGTQDSRISPYTFCKAFPFHIIFDRDLVVTQCGNAIYRVLPQLQPGKCSLLSVFSLVRPHIDISFHGILSHINTVFVLRSKEGLLDVEKLECEDELTGAEIS------CLRLKGQMIYLPEADSILFLCSPSVMNLDDLTRRGLYLSDIPLHDATRDLVLLGEQFREEYKLTQELEILTDRLQLTLRALEDEK-KKTDTLLYSVLPPSVANELRHKRPV--PAKRYDNVTILFSGIVGFNAFCSKHASGEGAMKIVNLLNDLYTRFDTLTDSRKNPFVYKVETVGDKYMTVSGLPEPCIHHARSICHLALDMMEIAGQVQVDGE---SVQITIGIHTGEVVTGVIGQRMPRYCLFGNTVNLTSRTETTGEKGKINVSEYTYRCLMSPENSDPQ-FHLEHRGPVSMKGKKEPMQVWF 603          

Query:  163 MYGLILEGVRQFICSKYGEDHWNSILRSADIDVI-TFGTHEVYGETLIPNIIESASRFLNMTVDEIMFLNGIFFINFVSQYGYDGILRVLGRDLRDFLNGLDNLHEYLRFSYPKLKPPSFFCVNESK-TGITLQYRTRRSGYIHYVRGQITEIARQFYSTEMSIEIVSQTSE--DNVSNCIMRLHFNNKNFIQIEDLLXXXXXXXX--------XXXXXNIVFNRGMRAINCGKGMLNALPDL-PHQL-ITEYFLLTRPLIEFTWDAVMLHTNNIFELIHLDPKISSSKILREGNHSSKKRTLSRNNPSLKMRGQMKYMPEWDAIVFLGTPIMRDVESMYKAGLFINDLSMHDSSRDLVLAGXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMKKTDELLFQMIPKSVAERLRHGSEAVDTCEHFDEVTILFSDVVGFTTICSK----INPFDVVEMLNKLYSVFDELTEKHK---VYKVETIGDAYMIASGCPTVTQYHAPFIIEMSLDMIKSIGFLMDPSDHSRSLQIRVGIHTGMVVAGVVGLKMPRYCLFGDTVNTASRMESNSEPQKIHISEAT-KAKVTDLQS---YKISERGHIDIKGKGNIKTYWL 1932
            MYG +   +   +   YG + W  I + A +D    F    +Y ++   +++ +AS+ LN+   EI+ + G  F  F  + GYD ILRVLG ++R+FL  LD LH++L   YP ++ PSF C +  K  G+ L Y + R G    V G I  +A+Q + TE+ ++++ Q +E  D+    I       ++F +  D                  + FPF+I+F+R +    CG  +   LP L P    +   F L RP I+ ++  ++ H N +F L   +  +   K+  E   +  + +       L+++GQM Y+PE D+I+FL +P + +++ + + GL+++D+ +HD++RDLVL GEQ   E KL  E E    +         DE  KKTD LL+ ++P SVA  LRH        + +D VTILFS +VGF   CSK         +V +LN LY+ FD LT+  K   VYKVET+GD YM  SG P    +HA  I  ++LDM++  G +    +   S+QI +GIHTG VV GV+G +MPRYCLFG+TVN  SR E+  E  KI++SE T +  +T   S   + +  RG + +KGK      W 
Sbjct:    1 MYGFVNHALELLVIRNYGPEVWEDIKKEAQLDEEGQFLVRIIYDDSKTYDLVAAASKVLNLNAGEILQMFGKMFFVFCQESGYDTILRVLGSNVREFLQNLDALHDHLATIYPGMRAPSFRCTDAEKGKGLILHYYSEREGLQDIVIGIIKTVAQQIHGTEIDMKVIQQRNEECDHTQFLIEEKESKEEDFYEDLDRFEENGTQESRISPYTFCKAFPFHIIFDRDLVVTQCGNAIYRVLPQLQPGNCSLLSVFSLVRPHIDISFHGILSHINTVFVLRSKEGLLDVEKLECEDELTGTEIS------CLRLKGQMIYLPEADSILFLCSPSVMNLDDLTRRGLYLSDIPLHDATRDLVLLGEQFREEYKLTQELEILTDRLQLTLRALEDEK-KKTDTLLYSVLPPSVANELRHKRPV--PAKRYDNVTILFSGIVGFNAFCSKHASGEGAMKIVNLLNDLYTRFDTLTDSRKNPFVYKVETVGDKYMTVSGLPEPCIHHARSICHLALDMMEIAGQVQVDGE---SVQITIGIHTGEVVTGVIGQRMPRYCLFGNTVNLTSRTETTGEKGKINVSEYTYRCLMTPENSDPQFHLEHRGPVSMKGKKEPMQVWF 603          

Query:  163 MYGLILEGVRQFICSKYGEDHWNSILRSADIDVITFGTHEVYGETLIPNIIESASRFLNMTVDEIMFLNGIFFINFVSQYGYDGILRVLGRDLRDFLNGLDNLHEYLRFSYPKLKPPSFFCVNESKTGITLQYRTRRSGYIHYVRGQITEIARQFYSTEMSIEIVSQTSED-NVSNCIMRLHFNNKNFIQIED-------LLXXXXXXXXXXXXXNIVFNRGMRAINCGKGMLNALPDLPHQLITEYFLLTRPLIEFTWDAVMLHTNNIFELIHLDPKISSSKILREGNHSSKKRTLSRNNPSLKMRGQMKYMPEWDAIVFLGTPIMRDVESMYKAGLFINDLSMHDSSRDLVLAGXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMKKTDELLFQMIPKSVAERLRHGSEAVDTCEHFDEVTILFSDVVGFTTICSKINPFDVVEMLNKLYSVFDELTEKHKVYKVETIGDAYMIASGCPTVTQYHAPFIIEMSLDMIKSIGFLMDPSDHSRSLQIRVGIHTGMVVAGVVGLKMPRYCLFGDTVNTASRMESNSEPQKIHISEATKAKVTDLQSYKISERGHI 1893
            MYGL+LEG+  FI SK+ ED W++IL  A  D   F T EVY + LIP I+++A   L M+ D+IMF NG+FFI F+S +GYD ILRVLGRDLRDFLNGLDNLHEYLRF+Y K++PPSFFCVNESKTGITLQYR++R G+ HYVRGQITEIAR FY T M IEIVS+T+E   V NCI RLHFNN  F  + D       L  VPSEVFFEVFPFNIVFNRGMR +N G+G+ N LP+L + LI E FLL RP+IEF+WDAV++HTNN+FELI ++ K+   +  +E +    K+  + ++  L+++GQMKYMP WDAIVFLGTP++RDVESMY  GL+INDLSMHDSSRDL+LAGEQQSAELKLALEQE EKS KL ES+ +LDE  KKTDELL+QMIPK+VA+RLR G  AV TCE FDEVTILFSD+ GFT IC  I P DVV MLN +YSVFD+LTE++ VYKVET+GDAYMI SG P  T++HAP + EM+ DMIK+I    DPS  +  L +R+G+HTGMVVAGVVG+KMPRYCLFGDTVNTA++MES+   Q+IHIS  TK K+   ++Y IS+   +
Sbjct:   19 MYGLLLEGIHAFITSKFSEDVWDAILARAKTDTRNFRTREVYSDGLIPLIVDAACEELRMSNDDIMFENGVFFITFLSNFGYDSILRVLGRDLRDFLNGLDNLHEYLRFTYVKMRPPSFFCVNESKTGITLQYRSKRRGFHHYVRGQITEIARLFYQTSMRIEIVSKTAEACGVVNCIFRLHFNNIRFAIVSDRLFESSPLCTVPSEVFFEVFPFNIVFNRGMRILNIGRGLFNTLPNLVNTLINENFLLIRPMIEFSWDAVIIHTNNVFELISMENKLQDGQASKERH----KKASNASDNGLRLKGQMKYMPAWDAIVFLGTPVLRDVESMYSVGLYINDLSMHDSSRDLILAGEQQSAELKLALEQEQEKSAKLTESMKRLDEEKKKTDELLYQMIPKTVADRLRRGDSAVSTCETFDEVTILFSDICGFTNICGAITPLDVVNMLNNMYSVFDKLTEQNCVYKVETVGDAYMIVSGAPVKTEHHAPLMSEMAQDMIKAIANCKDPSGINPHLMMRIGLHTGMVVAGVVGVKMPRYCLFGDTVNTANKMESSG--QRIHISATTKTKLDSYEAYVISDGSEV 597          

Query:  163 MYGLILEGVRQFICSKYGEDHWNSILRSADIDVITFGTHEVYGETLIPNIIESASRFLNMTVDEIMFLNGIFFINFVSQYGYDGILRVLGRDLRDFLNGLDNLHEYLRFSYPKLKPPSFFCVNESKTGITLQYRTRRSGYIHYVRGQITEIARQFYSTEMSIEIVSQTSEDNVSNCIMRLHFNNKNFIQIEDLLXXXXXXXXXXXXXNIVFNRGMRAINCGKGMLNALPDLPHQLITEYFLLTRPLIEFTWDAVMLHTNNIFELIHLDPKISSSKILREGNHSSKKRTLSRNNPSLKMRGQMKYMPEWDAIVFLGTPIMRDVESMYKAGLFINDLSMHDSSRDLVLAGXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMKKTDELLFQMIPKSVAERLRHGSEAVDTCEHFDEVTILFSDVVGFTTICSKINPFDVVEMLNKLYSVFDELTEKHKVYKVETIGDAYMIASGCPTVTQYHAPFIIEMSLDMIKSIGFLMDPS-DHSRSLQIRVGIHTGMVVAGVVGLKMPRYCLFGDTVNTASRMESNSEPQKIHISEATKAKVTDLQSYKISERGHIDIKGKGNIKTYWLDGH-NLENPKAVASLITQLERERITISDSNLAGSQI-KGDGWESLT 2064
            MYGL+L+G+R FI +K+  D WN I + A+   + F T  VY E L+PN+ ++++  L    D+I F  GI F+ +V   GY GILRVLGR+LRDFLNGLDNLH++LR +YPK++PPSFFCVNESKTGITLQYR+ R G++ +  G +TE++R  Y  EM IEIV Q         I+RLHF+N +F  IE+ LPVP+ VFFE FPFN VFNRGM+ +N G+ M NALP++  + +++ F L+RP+I FTWD VMLHTN IFEL   +    + +I      ++K   L  N   LK+RGQMKYM EWDAIVFLGTPIMRDV+SM + GL++NDLSMHDSSRD+VLAGEQQSAELKLALEQE+EKSK+LEESL +LDE M++TDELL+QMIP+SVA+RLR G  A+DTCE F+ VT+L SDVVGFTTICS + P +VV +LNKLYSVFD LTEKHKVYKVETIGDAYMIASGCPT T YH+PFI EM+LDM++S+  + D S +   SL+IRVGIHTG  VAGVVG+KMPRYCLFG TV T+  ME  S PQ+I +S      ++    Y ++E+G +++K  G I TYWL+G  N    +  A  + +L  ER  I+DSN+A SQ   G+ WES+T
Sbjct:    1 MYGLLLDGLRNFIVTKWSIDIWNEICQQANSSDVQFETRRVYDEALLPNLFKTSANILETPEDDIKFGMGITFVEYVGGKGYQGILRVLGRELRDFLNGLDNLHQFLRATYPKMQPPSFFCVNESKTGITLQYRSHRVGFVPFFCGWMTELSRVLYEKEMKIEIVGQKDRGKQVETILRLHFHNHSFASIEEELPVPAIVFFEAFPFNFVFNRGMKLLNIGRSMANALPNIVGKNVSDIFRLSRPVIPFTWDDVMLHTNIIFELTSNE---VNKEIALNDEQNNKGNELDSNRGKLKLRGQMKYMFEWDAIVFLGTPIMRDVDSMLEIGLYLNDLSMHDSSRDMVLAGEQQSAELKLALEQENEKSKRLEESLRRLDEEMRRTDELLYQMIPRSVAQRLRAGEAAMDTCETFENVTLLLSDVVGFTTICSGLAPLEVVGLLNKLYSVFDGLTEKHKVYKVETIGDAYMIASGCPTRTDYHSPFIAEMALDMVESVQTVKDESKEPPESLRIRVGIHTGPAVAGVVGVKMPRYCLFGSTVTTSELMEQTSSPQRIQVSVKAYENLSKYGVYDLTEKGTVELKDGGTILTYWLNGRPNPSECEKTAKFLDELNNEREKIADSNMASSQQHTGESWESVT 634          

Query:  163 MYGLILEGVRQFICSKYGEDHWNSILRSADIDVITFGTHEVYGETLIPNIIESASRFLNMTVDEIMFLNGIFFINFVSQYGYDGILRVLGRDLRDFLNGLDNLHEYLRFSYPKLKPPSFFCVNESKTGITLQYRTRRSGYIHYVRGQITEIARQFYSTEMSIEIVSQTSED-NVSNCIMRLHFNNKNFIQIEDLLXXXXXXXXXXXXX-------NIVFNRGMRAINCGKGMLNALPDLPHQLITEYFLLTRPLIEFTWDAVMLHTNNIFELIHLDPKISSSKILREGNHSSKKRTLSRNNPSLKMRGQMKYMPEWDAIVFLGTPIMRDVESMYKAGLFINDLSMHDSSRDLVLAGXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMKKTDELLFQMIPKSVAERLRHGSEAVDTCEHFDEVTILFSDVVGFTTICSKINPFDVVEMLNKLYSVFDELTEKHKVYKVETIGDAYMIASGCPTVTQYHAPFIIEMSLDMIKSIGFLMDPSDHSRSLQIRVGIHTGMVVAGVVGLKMPRYCLFGDTVNTASRMESNSEPQKIHISEATKAKVTDLQSYKISERGHI 1893
            MYGL+LEG+  FI SK+ ED W++IL  A  D   F T EVY + LIP I+++A   L M+ D+IMF NG+FFI F+S +GYD ILRVLGRDLRDFLNGLDNLHEYLRF+Y K++PPSFFCVNESKTGITLQYR++R G+ HYVRGQITEIAR FY T M IEIVS+T+E   V NCI RLHFNN  F  + D L   S +              NIVFNRGMR +N G+G+ N LP+L + LI E FLL RP+IEF+WDAV++HTNN+FELI ++ K+   +  +E +    K+  + ++  L+++GQMKYMP WDAIVFLGTP++RDVESMY  GL+INDLSMHDSSRDL+LAGEQQSAELKLALEQE EKS KL ES+ +LDE  KKTDELL+QMIPK+VA+RLR G  AV TCE FDEVTILFSD+ GFT IC  I P DVV MLN +YSVFD+LTE++ VYKVET+GDAYMI SG P  T++HA  + EM+ DMIK+I    DPS  +  L +R+G+HTGMVVAGVVG+KMPRYCLFGDTVNTA++MES+   Q+IHIS  TK K+   ++Y IS+   +
Sbjct:   19 MYGLLLEGIHAFITSKFSEDVWDAILARAKTDTRNFRTREVYSDGLIPLIVDAACEELRMSNDDIMFENGVFFITFLSNFGYDSILRVLGRDLRDFLNGLDNLHEYLRFTYVKMRPPSFFCVNESKTGITLQYRSKRRGFHHYVRGQITEIARLFYQTNMRIEIVSKTAEACGVVNCIFRLHFNNIRFAIVSDRLFESSSLCTVPSEVFFEVFPFNIVFNRGMRILNIGRGLFNTLPNLVNTLINENFLLIRPMIEFSWDAVIIHTNNVFELISMENKLQDGQASKERH----KKASNASDNGLRLKGQMKYMPAWDAIVFLGTPVLRDVESMYSVGLYINDLSMHDSSRDLILAGEQQSAELKLALEQEQEKSAKLTESMKRLDEEKKKTDELLYQMIPKTVADRLRRGDSAVSTCETFDEVTILFSDICGFTNICGAITPLDVVNMLNNMYSVFDKLTEQNCVYKVETVGDAYMIVSGAPVKTEHHAALMSEMAQDMIKAIANCKDPSGINPHLMMRIGLHTGMVVAGVVGVKMPRYCLFGDTVNTANKMESSG--QRIHISATTKTKLDSYEAYVISDGSEV 597          

Query:  163 MYGLILEGVRQFICSKYGEDHWNSILRSADIDVITFGTHEVYGETLIPNIIESASRFLNMTVDEIMFLNGIFFINFVSQYGYDGILRVLGRDLRDFLNGLDNLHEYLRFSYPKLKPPSFFCVNESKTGITLQYRTRRSGYIHYVRGQITEIARQFYSTEMSIEIVSQTSEDNVSNCIMRLHFNNKNFIQIEDLLXXXXXXXXXXXXXNIVFNRGMRAINCGKGMLNALPDLPHQLITEYFLLTRPLIEFTWDAVMLHTNNIFELIHLDPKISSSKILREGNHSSKKRTLSRNNPSLKMRGQMKYMPEWDAIVFLGTPIMRDVESMYKAGLFINDLSMHDSSRDLVLAGXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMKKTDELLFQMIPKSVAERLRHGSEAVDTCEHFDEVTILFSDVVGFTTICSKINPFDVVEMLNKLYSVFDELTEKHKVYKVETIGDAYMIASGCPTVTQYHAPFIIEMSLDMIKSIGFLMDPS-DHSRSLQIRVGIHTGMVVAGVVGLKMPRYCLFGDTVNTASRMESNSEPQKIHISEATKAKVTDLQSYKISERGHIDIKGKGNIKTYWLDGH-NLENPKAVASLITQLERERITISDSNLAGS-QIKGDGWESLT 2064
            MYGL+LEG+R FI +K+  + W  I   A+   I F T +VY E L+PN+ + +S+ L+   DEI F  GI F+ +V   GY GILRVLGR+LRDFLNGLDNLHE+LR SYPK++PPSFFCVNES+TGITLQYR+ R+G++ +  G +TE+A+  YS +M +EIV Q         I+RLHF+N +F +I++ LPVP+ VFFE FPFN VFNRGM+ +N G+ M NALP++  + + + FLL+RP+I FTWD +MLHTN IFEL   +     + I  + N   +  T   N   LK+RGQMKYM EWDAIVFLGTPIMRDV+SM + GL++NDLSMHDSSRD+VLAGEQQSAELKLALEQE+EKSK+LEESL +LDE M++TDELL+QMIP+SVAERLR G  AVDTCE FD VT+L SDVVGFTTICS + P +VV +LNKLYSVFD LTEKHKVYKVETIGDAYMIASGCP+ T+YHAPFI EM+LDM++S+  + D S +   SL+IRV    G  VAGVVG+KMPRYCLFG TV T+  ME  S PQ+I +S      ++    Y ++E+G +++K  G I TYWL+G  N  + +  A  + +L  ER  I+DSN+A S Q  G+ WES+T
Sbjct:    1 MYGLLLEGLRNFIITKWSSEIWIEICTQANSPEIQFETRKVYDEALLPNLFQISSKLLDTPEDEIKFGMGISFVEYVGSKGYQGILRVLGRELRDFLNGLDNLHEFLRSSYPKIRPPSFFCVNESRTGITLQYRSHRTGFVPFFCGWMTELAKVLYSKDMKVEIVGQKDRGKQVETILRLHFHNHSFNEIDEELPVPAIVFFEAFPFNFVFNRGMKLLNIGRSMANALPNIVGKNVVDIFLLSRPVIPFTWDDIMLHTNIIFELTSNEISKEVNLIDEQNNTGDQSDT---NRGRLKLRGQMKYMSEWDAIVFLGTPIMRDVDSMLEIGLYLNDLSMHDSSRDMVLAGEQQSAELKLALEQENEKSKRLEESLRRLDEEMRRTDELLYQMIPRSVAERLRAGEAAVDTCETFDNVTLLLSDVVGFTTICSGLAPLEVVSLLNKLYSVFDGLTEKHKVYKVETIGDAYMIASGCPSRTEYHAPFIAEMALDMVESVQTVKDESKEPPESLRIRV----GPAVAGVVGVKMPRYCLFGSTVTTSELMEQTSSPQRIQVSVKAYENLSKYGVYDLTEKGRVELKDGGTILTYWLNGRSNPSDDEKTAKFLDELNTERERIADSNMASSYQRSGESWESVT 630          

Query:  163 MYGLILEGVRQFICSKYGEDHWNSILRSADIDVITFGTHEVYGETLIPNIIESASRFLNMTVDEIMFLNGIFFINFVSQYGYDGILRVLGRDLRDFLNGLDNLHEYLRFSYPKLKPPSFFCVNESKTGITLQYRTRRSGYIHYVRGQITEIARQFYSTEMSIEIVSQTSEDNVSNCIMRLHFNNKNFIQIEDLLXXXXXXXXXXXXXNIVFNRGMRAINCGKGMLNALPDLPHQLITEYFLLTRPLIEFTWDAVMLHTNNIFELIHLDPKISSSKILREGNHSSKKRTLSRNNPSLKMRGQMKYMPEWDAIVFLGTPIMRDVESMYKAGLFINDLSMHDSSRDLVLAGXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMKKTDELLFQMIPKSVAERLRHGSEAVDTCEHFDEVTILFSDVVGFTTICSKINPFDVVEMLNKLYSVFDELTEKHKVYKVETIGDAYMIASGCPTVTQYHAPFIIEMSLDMIKSIGFLMDPSDH-SRSLQIRVGIHTGMVVAGVVGLKMPRYCLFGDTVNTASRMESNSEPQKIHISEATKAKVTDLQSYKISERGHIDIKGKGNIKTYWLDGHNLEN-PKAVASLITQLERERITISDSNLAGSQIK-GDGWESLTHXXXXXXXXXTGSILELSHTKRLASINHGDSV 2160
            MYGL++EG + ++ ++Y +  W  IL+ +  +  TF + +VY E ++P +  +ASR L +  DEI +  G  F+ F+   GY GILRVLGR L+DFLNGLDNLHE+LR SYP++KPPSFFCVNES++GITL+YR+ R+ Y+ +  G +  ++  F+ TEM I ++    E+  +  I+RLHF+N ++I+  +  P+P+ VFFE FPFN VF+RGM+ IN G+ M NALP++  + +++ F++ RPLI+  W+A+MLHTNNIFEL   +  +  ++I      S K+ T       L++RGQMK+M EWDAIVF+GTPIM+DV++M++ GLF+NDLSMHDSSRD+VL GEQQ+AELKLALEQESEKS++L ESLH LDE MK+TDELL+QMIPK+VAERLR+G  AV TCE F+E+T+L SDVVGFT ICS ++P +VV +LN+LYS FD LTEKHKVYKVETIGDAY+IASGCP  T+YHAPFI EM+LDM+ S+  + D S +   SL+IR+G+HTG  VAGVVG+KMPRYCLFG TV T   ME+ S PQKI +SE T AK+     Y +S +G   +K  G I+T+WL+G   E   +  A L  ++++ER  ++DSNL+  Q + G+GWES++ SR SSAR         +HT R +S+  G  V
Sbjct:    1 MYGLVIEGFKSYVSAQYSDSIWEEILKQSGYESYTFDSKQVYDEAILPALFTTASRMLQIPEDEIKYATGKSFVRFMCNKGYGGILRVLGRQLKDFLNGLDNLHEFLRCSYPEMKPPSFFCVNESRSGITLEYRSHRANYVSFFMGYMEAVSLTFFKTEMKITVIVPADENLQTATILRLHFDNTSYIRPAEKKPLPARVFFEAFPFNFVFDRGMKLINVGRSMANALPNILGKKVSDVFIVKRPLIQLNWNAIMLHTNNIFELTSTNYDVVDTEI----EESGKEMTCLPQKGCLRLRGQMKFMSEWDAIVFIGTPIMQDVDAMWEVGLFLNDLSMHDSSRDMVLTGEQQAAELKLALEQESEKSRRLTESLHHLDEEMKRTDELLYQMIPKAVAERLRNGEPAVATCEKFEEITLLLSDVVGFTNICSGLSPLEVVNLLNRLYSCFDALTEKHKVYKVETIGDAYIIASGCPIRTKYHAPFIAEMALDMVNSVQMVKDESKNPPESLRIRIGMHTGPTVAGVVGVKMPRYCLFGSTVTTVEVMEATSAPQKIQVSETTHAKLKVYGVYDMSPKGDAQLKDGGVIRTHWLNGRRQETMCEITAKLCEEMDQERSRLADSNLSSHQQQSGEGWESMSASRCSSAR---------THTSRRSSMARGSLV 656          

Query:  157 LAMYGLILEGVRQFICSKYGEDHWNSILRSADIDVITFGTHEVYGETLIPNIIESASRFLNMTVDEIMFLNGIFFINFVSQYGYDGILRVLGRDLRDFLNGLDNLHEYLRFSYPKLKPPSFFCVNESKTGITLQYRTRRSGYIHYVRGQITEIARQFYSTEMSIEIVSQTSEDNVSNCIMRLHFNNK--NFIQIED-----LLXXXXXXXXXXXXXNIVFNRGMRAINCGKGMLNALPDLPHQLITEYFLLTRPLIEFTWDAVMLHTNNIFELIHLDP---------KISSSKI-----------------------LREGNHSSKKRTLSRNNPSLKMRGQMKYMPEWDAIVFLGTPIMRDVESMYKAGLFINDLSMHDSSRDLVLAGXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMKKTDELLFQMIPKSVAERLRHGSEAVDTCEHFDEVTILFSDVVGFTTICSKINPFDVVEMLNKLYSVFDELTEKHKVYKVETIGDAYMIASGCPTVTQYHAPFIIEMSLDMIKSIGFLMDPSDHSRSLQIRVGIHTGMVVAGVVGLKMPRYCLFGDTVNTASRMESNSEPQKIHISEATKAKVTDLQSYKISERGHIDIKGKGNIKTYWLDGHNLENPKAVASLITQLERERITISDSNLAGSQIKGDG 2049
            ++MYGL+ E +  FI   YG+D W  +   AD+ + +F TH+VY E++IP I ++AS       +E+M   G++F+ FV +YGYD IL+VLGR +RDF+NGLDNLHEYLRFSYPK++PP+FFC  ES TG+TL YR++R GY+HY  GQ+ ++ +QFY T++ +E++S+    + S+  MRL+F+N    +IQ ED     +LP+ S+ FFEVFPFNIVF + M   N G G+    PDL  + I + FLL RPL+EFTW+ ++ H NN+FE++  +P         ++ +S                          ++GN ++   +    +  LK++GQM+YMPEW++I+FLGTP+M  + +M+K GL+INDLSMHDSSRDLVLAG QQS ELK AL QE +KS KLEES+  LD  MKKTD+LL++MIPK VA+RLR G  AV+TCE F +VTILFSDVVGFT ICS I P  VV MLN +Y++FD L+EKH+V+KVETIGDAYM+ +G P  T+YHA  I +M+LDM++SI  L DPS+   ++QIRVGIH+GMVVAGVVG KMPRY L GDTV+TAS MESN +   I +S AT   +     +    RG I IKG   I+TYWL G   ++  A A+   Q E + I+ + ++     I  +G
Sbjct:   33 VSMYGLLCESLHDFIKESYGDDVWKLVRERADVRLHSFVTHQVYSESVIPRIAKAASGVTGTPYNELMNSWGVYFLGFVGKYGYDRILKVLGRHVRDFVNGLDNLHEYLRFSYPKVQPPTFFCQEESATGVTLHYRSKRKGYLHYAMGQLRQMGKQFYDTDIHVEVLSEQLVGDYSHVTMRLNFDNSAYRYIQKEDEEEQEILPITSDFFFEVFPFNIVFRQDMVVHNVGSGLATVFPDLDGKKINDAFLLARPLVEFTWNMIISHPNNLFEIMSKEPVKRERNLHNRVQNSDYENANRSADVDVELMAFQSIIGDDYKDGNSANAMESWGDGSRCLKLKGQMRYMPEWESIIFLGTPVMESLSAMFKTGLYINDLSMHDSSRDLVLAGTQQSEELKRALIQEQKKSSKLEESMKMLDYEMKKTDDLLYRMIPKPVAKRLRKGEPAVNTCEVFPDVTILFSDVVGFTRICSHITPMQVVSMLNTMYTLFDTLSEKHRVFKVETIGDAYMVVAGAPEKTKYHAHNICDMALDMVRSIDHLKDPSN-GNNIQIRVGIHSGMVVAGVVGHKMPRYGLHGDTVHTASAMESNGKEMHIQLSSATYEHLKG-SHFIFERRGTITIKGNVEIETYWLKGKRDKDGNAQAA-CPQFEAQTISKAAASPPEPPIDEEG 699          

Query:  598 GQITEIARQFYSTEMSIEIVSQTSEDNVSNCIMRLHFNNK--NFIQIED-----LLXXXXXXXXXXXXXNIVFNRGMRAINCGKGMLNALPDLPHQLITEYFLLTRPLIEFTWDAVMLHTNNIFELIHLDP---------KISSSKI-----------------------LREGNHSSKKRTLSRNNPSLKMRGQMKYMPEWDAIVFLGTPIMRDVESMYKAGLFINDLSMHDSSRDLVLAGXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMKKTDELLFQMIPKSVAERLRHGSEAVDTCEHFDEVTILFSDVVGFTTICSKINPFDVVEMLNKLYSVFDELTEKHKVYKVETIGDAYMIASGCPTVTQYHAPFIIEMSLDMIKSIGFLMDPSDHSRSLQIRVGIHTGMVVAGVVGLKMPRYCLFGDTVNTASRMESNSEPQKIHISEATKAKVTDLQSYKISERGHIDIKGKGNIKTYWLDGHNLENPKAVASLITQLERERITISDSNLAGSQIKGDG 2049
            GQ+ ++ +QFY T++ +E++S+    + S+  MRL+F+N    +IQ ED     +LP+ S+ FFEVFPFNIVF + M   N G G+    PDL  + I + FLL RPL+EFTW+ ++ H NN+FE++  +P         ++ +S                          ++GN ++   +    +  LK++GQM+YMPEW++I+FLGTP+M  + +M+K GL+INDLSMHDSSRDLVLAG QQS ELK AL QE +KS KLEES+  LD  MKKTD+LL++MIPK VA+RLR G  AV+TCE F +VTILFSDVVGFT ICS I P  VV MLN +Y++FD L+EKH+V+KVETIGDAYM+ +G P  T+YHA  I +M+LDM++SI  L DPS+   ++QIRVGIH+GMVVAGVVG KMPRY L GDTV+TAS MESN +   I +S AT   +     +    RG I IKG   I+TYWL G   ++  A A+   Q E + I+ + ++     I  +G
Sbjct:    2 GQLRQMGKQFYDTDIHVEVLSEQLVGDYSHVTMRLNFDNSAYRYIQKEDEEEQEILPITSDFFFEVFPFNIVFRQDMVVHNVGSGLATVFPDLDGKKINDAFLLARPLVEFTWNMIISHPNNLFEIMSKEPVKRERNLHNRVQNSDYENANRSADVDVELMAFQSIIGDDYKDGNSANAMESWGDGSRCLKLKGQMRYMPEWESIIFLGTPVMESLSAMFKTGLYINDLSMHDSSRDLVLAGTQQSEELKRALIQEQKKSSKLEESMKMLDYEMKKTDDLLYRMIPKPVAKRLRKGEPAVNTCEVFPDVTILFSDVVGFTRICSHITPMQVVSMLNTMYTLFDTLSEKHRVFKVETIGDAYMVVAGAPEKTKYHAHNICDMALDMVRSIDHLKDPSN-GNNIQIRVGIHSGMVVAGVVGHKMPRYGLHGDTVHTASAMESNGKEMHIQLSSATYEHLKG-SHFIFERRGTITIKGNVEIETYWLKGKRDKDGNAQAAC-PQFEAQTISKAAASPPEPPIDEEG 521          

Query: 1048 LKMRGQMKYMPEWDAIVFLGTPIMRDVESMYKAGLFINDLSMHDSSRDLVLAGXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMKKTDELLFQMIPKSVAERLRHGSEAVDTCEHFDEVTILFSDVVGFTTICSKINPFDVVEMLNKLYSVFDELTEKHKVYKVETIGDAYMIASGCPTVTQYHAPFIIEMSLDMIKSIGFLMDPSDHSRSLQIRVGIHTGMVVAGVVGLKMPRYCLFGDTVNTASRMESNSEPQKIHISEATKAKVTDLQSYKISERGHIDIKGKGNIKTYWLDG 1938
            L ++GQMKY+P+WD+++FLGTPI+  VE M K G+++NDL++HDSSR+L+LAG QQSAEL+LAL+QE +K  +L+E + KLDE  K+ D LL+ MIPK+VA+RLR G  A++TC+ F +VTILFSDVV F  IC  I P  VV+MLN++Y VFD L+EKH VYKVETI DAYM+ +G P  T +HA  I +M+LDM+ SI  L DPS    ++QIRVGIH+GMVVAGVVGLKMPRYCLFGDTVNTASRMESN    +IHIS+ TK  + + + Y I ERG I +KGKG +KTYWL G
Sbjct:  370 LHLKGQMKYVPQWDSLIFLGTPIIETVEDMIKMGVYVNDLNLHDSSRELILAGTQQSAELQLALDQEQQKYAQLQEIIKKLDEEKKRGDSLLYAMIPKAVADRLRKGITALETCQVFPDVTILFSDVVKFNEICIHITPMQVVDMLNEIYIVFDTLSEKHNVYKVETIRDAYMVVAGVPNKTTFHAHHICDMALDMLSSIDHLKDPST-GDNIQIRVGIHSGMVVAGVVGLKMPRYCLFGDTVNTASRMESNGVGMQIHISQTTKDHL-EHEPYIIEERGKIFVKGKGYMKTYWLKG 664          

Query:  163 MYGLILEGVRQFICSKYGEDHWNSILRSADIDVITFGTHEVYGETLIPNIIESASRFLNMTVDEIMFLNGIFFINFVSQYGYDGILRVLGRDLRDFLNGLDNLHEYLRFSYPKLKPPSFFCVNESKTGITLQYRTRRSGYIHYVRGQITEIARQFYSTEMSIEIVSQTSEDNVSNCIMRLHFNNKNFIQI---------EDLLXXXXXXXXXXXXXNIVFNRGMRAINCGKGMLNALPDLPHQLITEYFLLTRPLIEFTWDAVMLHTNNIFELI 957
            MYGL LE V  +I   YGED W  I   A+I  + F  H++Y + LI  + ++A   L  T DE+M+  G++ +  +  YGY+ IL+VLGR++RDF+N LDNLHEY RFS+PK++PPSF    E +T +TL YR+ R G+  +V+GQ++++ RQFY+T++ +EI+S+   + ++  + +++F+N  F             + LP+   +FF++FPF+++F R M     G G+     DL  + + E F L RP++EF+WD +  H NN+FEL+
Sbjct:    1 MYGLYLEAVNDYINESYGEDVWRLIEARAEIPHLKFVRHQMYNDNLILRLAKAAGEVLGKTHDELMYAFGVYMVKRIGNYGYERILKVLGRNVRDFINELDNLHEYFRFSFPKVQPPSFCVEEECETSLTLHYRSTRKGFTQFVKGQLSQVGRQFYNTDIEVEILSKEETEKMTYVVYKMNFDNAAFKHRMPQQKTAPGYEKLPMKRGIFFDMFPFSVIFRRDMTMYRIGDGLKEVFSDLQGKKVNEEFTLVRPMLEFSWDNIYTHLNNVFELL 274          

Query:  163 MYGLILEGVRQFICSKYGEDHWNSILRSADIDVITFGTHEVYGETLIPNIIESASRFLNMTVDEIMFLNGIFFINFVSQYGYDGILRVLGRDLRDFLNGLDNLHEYLRFSYPKLKPPSFFCVNESKTGITLQYRTRRSGYIHYVRGQITEIARQFYSTEMSIEIVSQTSED--------------------------------NVSNCIMRLHFNNKNFIQIEDLLXXXXXXXXXXXXXNIVFNRGMRAINCGKGMLNALPDLPHQ--LITEYFLLTRPLIEFTWDAVMLHTNNIFELIHLDPKISSSKILREGNHSSKKRTLSRNNPSLKMRGQMKYMPEWDAIVFLGTPIMRDVESMYKAGLFINDLSMHDSSRDLVLAGXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMKKTDELLFQMIPKSVAERLRHGSEAVDTCEHFDEVTILFSDVVGFTTICSKINPFDVVEMLNKLYSVFDELTEKHKVYKVETIGDAYMIASGCPTVTQYHAPFIIEMSLDMIKSIGFLMDPSDHSRSLQIRVGIHTGMVVAGVVGLKMPRYCLFGDTVNTASRMESNSEPQKIHISEATKAKVTDLQSYKISERGHIDIKGKGNIKTYWL 1932
            MYG I   +R  +  K+GE+ W  +   A++   TF T+E+Y + +   +++ A + L+++ + ++ L G +F +F    GYD +LR LG +L +F+  LD LH YL  SY ++  PSF     +     L Y + R G  + V G I  +A+ F+ +++++ I+ Q  E                                  V   +M  H  +    +    L +  + F   FPF+IVF++ +   + G  +   +P L      + EYF +  P +     ++    N+ F L          K  RE    S +     N   LK+RGQM +M     +V+L +P +R ++ + + GL + D++ HD++RDL+L  +Q+ AE++L+ + E +K +    S +   E  KKT+ LL+ M+P+ VA +L+ G + VD  E F   TILFSDVV FT IC+   P  +V MLN +YS FD LT  H VYKVETIGDAYM+  G P     HA  +   +L M  +   + +P    + +QIRVG+HTG V+AGVVG KMPRYCLFGDTVNTASRMES+  P  IH+S  T + + D + ++I ERG I +KGKG + TY+L
Sbjct:    1 MYGFINTCLRTLVVEKFGEETWEKLRLLAEVQ-DTFMTYEIYDDVITLRLVQEACKMLDVSSEVVLKLFGEYFFSFCKMSGYDTMLRTLGGNLVEFIENLDALHSYLALSYEEMNAPSFRVERTNDGRTLLHYYSDRKGLHYIVPGIIEAVAKDFFGSKVTMTILEQPKEQERTGKREHVIFLMTQTSEGAKGEEAHLNGGDGTVERKVMSDHIQHSFCPRYPKRLWIEEQAFCNAFPFHIVFDQNLVVKHTGVNIQKFVPGLQKTGCRLDEYFSVVHPEVTLNIHSIKKFINSQFVL----------KTRREMLPESLQ-----NQTMLKLRGQMVWMESLHCMVYLCSPKLRSLQELEERGLHLADIAQHDTTRDLILLNQQRLAEIELSNQLERKKEELRILSRNLEVEK-KKTETLLYAMLPRHVANQLKEGKK-VDAGE-FKVCTILFSDVVTFTNICAACEPIQIVHMLNSMYSRFDRLTNVHDVYKVETIGDAYMVVGGVPIPKDTHAERVANFALGMRIAAREVTNPIT-GKPIQIRVGLHTGPVLAGVVGEKMPRYCLFGDTVNTASRMESHGVPDHIHLSPFTYSALKD-KMFEIRERGEIQVKGKGLMDTYFL 603          

Query:  154 LLAMYGLILEGVRQFICSKYGEDHWNSILRSADIDVITFGTHEVYGETLIPNIIESASRFLNMTVDEIMFLNGIFFINFVSQYGYDGILRVLGRDLRDFLNGLDNLHEYLRFSYPKLKPPSFFCVNESKTGITLQYRTRRSGYIHYVRGQITEIARQFYSTEMSIEIVSQTSED--------------------------------NVSNCIMRLHFNNKNFIQIEDLLXXXXXXXXXXXXXNIVFNRGMRAINCGKGMLNALPDLPHQ--LITEYFLLTRPLIEFTWDAVMLHTNNIFELIHLDPKISSSKILREGNHSSKKRTLSRNNPSLKMRGQMKYMPEWDAIVFLGTPIMRDVESMYKAGLFINDLSMHDSSRDLVLAGXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMKKTDELLFQMIPKSVAERLRHGSEAVDTCEHFDEVTILFSDVVGFTTICSKINPFDVVEMLNKLYSVFDELTEKHKVYKVETIGDAYMIASGCPTVTQYHAPFIIEMSLDMIKSIGFLMDPSDHSRSLQIRVGIHTGMVVAGVVGLKMPRYCLFGDTVNTASRMESNSEPQKIHISEATKAKVTDLQSYKISERGHIDIKGKGNIKTYWL 1932
            L + YG I   +R  +  K+GE+ W  +   A++   TF T+E+Y + +   +++ A + L+++ + ++ L G +F +F    GYD +LR LG +L +F+  LD LH YL  SY ++  PSF     +     L Y + R G  + V G I  +A+ F+ +++++ I+ Q  E                                  V   +M  H  +    +    L +  + F   FPF+IVF++ +   + G  +   +P L      + EYF +  P +     ++    N+ F L          K  RE    S +     N   LK+RGQM +M     +V+L +P +R ++ + + GL + D++ HD++RDL+L  +Q+ AE++L+ + E +K +    S +   E  KKT+ LL+ M+P+ VA +L+ G + VD  E F   TILFSDVV FT IC+   P  +V MLN +YS FD LT  H VYKVETIGDAYM+  G P     HA  +   +L M  +   + +P    + +QIRVG+HTG V+AGVVG KMPRYCLFGDTVNTASRMES+  P  IH+S  T + + D + ++I ERG I +KGKG + TY+L
Sbjct:    4 LPSQYGFINTCLRTLVVEKFGEETWEKLRLLAEVQ-DTFMTYEIYDDVITLRLVQEACKMLDVSSEVVLKLFGEYFFSFCKMSGYDTMLRTLGGNLVEFIENLDALHSYLALSYEEMNAPSFRVERTNDGRTLLHYYSDRKGLHYIVPGIIEAVAKDFFGSKVTMTILEQPKEQERTGKREHVIFLMTQTSEGAKGEEAHLNGGDGTVERKVMSDHIQHSFCPRYPKRLWIEEQAFCNAFPFHIVFDQNLVVKHTGVNIQKFVPGLQKTGCRLDEYFSVVHPEVTLNIHSIKKFINSQFVL----------KTRREMLPESLQ-----NQTMLKLRGQMVWMESLHCMVYLCSPKLRSLQELEERGLHLADIAQHDTTRDLILLNQQRLAEIELSNQLERKKEELRILSRNLEVEK-KKTETLLYAMLPRHVANQLKEGKK-VDAGE-FKVCTILFSDVVTFTNICAACEPIQIVHMLNSMYSRFDRLTNVHDVYKVETIGDAYMVVGGVPIPKDTHAERVANFALGMRIAAREVTNPIT-GKPIQIRVGLHTGPVLAGVVGEKMPRYCLFGDTVNTASRMESHGVPDHIHLSPFTYSALKD-KMFEIRERGEIQVKGKGLMDTYFL 609          

Query:  868 ITEYFLLTRPLIEFTWDAVMLHTNNIFELIHLDPKISSSKILREGNHSSKKRTLSRNNPSLKMRGQMKYMPEWDAIVFLGTPIMRDVESMYKAGLFINDLSMHDSSRDLVLAGXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMKKTDELLFQMIPKSVAERLRHGSEAVDTCEHFDEVTILFSDVVGFTTICSKINPFDVVEMLNKLYSVFDELTEKHKVYKVETIGDAYMIASGCPTVTQYHAPFIIEMSLDMIKSIGFLMDPSDHSRSLQIRVGIHTGMVVAGVVGLKMPRYCLFGDTVNTASRMESNSEPQKIHISEATKAKVTDLQSYKISERGHIDIKGKGNIKTYWLDGH 1941
            + EYF +  P + FT +++    N+ F L          K  RE    ++     R+ P L +RGQM +M    ++++L +P++R +E + +  L I+D++ HD++RDL+L  +Q+ AE++L+ + E +K +    S +   E  KKT+ LL+ M+P  VA +L+ G + V+  E F   TILFSDVV FT IC+   P  +V MLN +Y  FD LT  H VYKVETIGDAYM+  G P     HA  +   +L M+ +   + +P   S ++QIRVGIH+G V+AGVVG KMPRYCLFGDTVNTASRMES+  P +IH+S +T+  +   + + + ERG I++KGKG + TY+L G+
Sbjct:   24 LDEYFTIGHPEVTFTIESIRKFINSQFVL----------KTRREMLPEAR-----RSQPMLDLRGQMVWMEGSRSMLYLCSPLLRSLEELEERQLHISDIAPHDATRDLILLNQQRLAEMELSTQLERKKEELRVLSKNLQVEK-KKTEALLYAMLPHHVANQLKEGKK-VEAGE-FKVCTILFSDVVTFTNICAVCEPIQIVHMLNAMYMRFDRLTTVHNVYKVETIGDAYMVVGGVPIPVPSHAERVANFALGMVLAAREVTNPVTGS-AIQIRVGIHSGPVLAGVVGEKMPRYCLFGDTVNTASRMESHGLPGRIHLSPSTREALQG-KEFDVEERGEIEVKGKGRMSTYFLLGN 361          

Query: 1303 KKTDELLFQMIPKSVAERLRHGSEAVDTCEHFDEVTILFSDVVGFTTICSKINPFDVVEMLNKLYSVFDELTEKHKVYKVETIGDAYMIASGCPTVTQ-YHAPFIIEMSLDMIKSIGFLMDPSDHSRSLQIRVGIHTGMVVAGVVGLKMPRYCLFGDTVNTASRMESNSEPQKIHISEATKAKVTDLQSYKISERGHIDIKGKGNIKTYWLDGHNLENPK 1959
            +KTD LL+ M+PK +A+ LR G   V   + +   T+ FSD+VGFT + S   P++VV+ LNKLY+ FD + + + VYKVETIGDAYM+ SG PT     HA     M+LD++      + P      L+IR GIHTG VVAGVVG KMPRYCLFGDTVNTASRMES SE  KI  S +T + +  + SY +S RG + +KGKG + T+WL+G +    K
Sbjct:  286 QKTDRLLYSMLPKQIADDLRQGR--VTKAQSYASATVFFSDIVGFTQLSSSSTPYEVVDFLNKLYTSFDGIIDNYDVYKVETIGDAYMVVSGVPTENHNQHAVETANMALDLVNVCQAFVIPHKPEMQLKIRAGIHTGPVVAGVVGTKMPRYCLFGDTVNTASRMESTSEALKIQCSPSTSSILQQIGSYLLSCRGTVTVKGKGEMITWWLEGRDTSTKK 503          

Query: 1303 KKTDELLFQMIPKSVAERLRHGSEAVDTCEHFDEVTILFSDVVGFTTICSKINPFDVVEMLNKLYSVFDELTEKHKVYKVETIGDAYMIASGCPTVT-QYHAPFIIEMSLDMIKSIGFLMDPSDHSRSLQIRVGIHTGMVVAGVVGLKMPRYCLFGDTVNTASRMESNSEPQKIHISEATKAKVTDLQSYKISERGHIDIKGKGNIKTYWLDGHNLENPKA 1962
            +K + LL+Q++P SVAE+L+ G E V   E FD VTI FSD+VGFT++ ++  P  VV +LN LY+ FD + +   VYKVETIGDAYM+ SG P    + +A  I  MSL ++ ++            L++R+GIHTG V AGVVGLKMPR+CLFGDTVNTASRMESN E  KIH+S+ TK  + +   +++  RG +++KGKG ++TYWL G   ENP+A
Sbjct:  609 RKAETLLYQILPHSVAEQLKRG-ETVQA-EAFDSVTIYFSDIVGFTSLSAESTPMQVVTLLNDLYTCFDAIIDNFDVYKVETIGDAYMVVSGLPVRNGKLNAKEIARMSLALLDAVKTFKIRHRQEDKLKLRIGIHTGPVCAGVVGLKMPRFCLFGDTVNTASRMESNGEALKIHVSQTTKEVLDEFGCFRLELRGDVEMKGKGKMRTYWLLGEIEENPEA 827          

Query: 1306 KTDELLFQMIPKSVAERLRHGSEAVDTCEHFDEVTILFSDVVGFTTICSKINPFDVVEMLNKLYSVFDELTEKHKVYKVETIGDAYMIASGCPTVT-QYHAPFIIEMSLDMIKSIGFLMDPSDHSRSLQIRVGIHTGMVVAGVVGLKMPRYCLFGDTVNTASRMESNSEPQKIHISEATKAKVTDLQSYKISERGHIDIKGKGNIKTYWLDGHN 1944
            K + LL+Q++P SVAE+L+ G       E FD VTI  SD+VGFT + ++  P  VV  LN LY+ FD + +   VYKVETIGDAYM+ SG P      HA  +  M+L ++ ++         ++ L +R+GIHTG V AGVVGLKMPRYCLFGDTVNTASRME+  E  +IH+S  TKA + +   + +   G +DIKGKG ++TYWL G N
Sbjct:  293 KAEALLYQILPHSVAEQLKRGETV--PAEAFDSVTIYLSDIVGFTAMSAQSTPMQVVAFLNDLYTCFDAIIDNFDVYKVETIGDAYMVVSGLPVHNGTRHAIEVARMALALLSAVRCFHIRHRPAQRLLLRIGIHTGPVCAGVVGLKMPRYCLFGDTVNTASRMEAKGEAHRIHLSSTTKAILDEYGGFVVQLHGDVDIKGKGTMRTYWLLGEN 504          

Query: 1306 KTDELLFQMIPKSVAERLRHGSEAVDTCEHFDEVTILFSDVVGFTTICSKINPFDVVEMLNKLYSVFDELTEKHKVYKVETIGDAYMIASGCPTVTQ-YHAPFIIEMSLDMIKSIGFLMDPSDHSRSLQIRVGIHTGMVVAGVVGLKMPRYCLFGDTVNTASRMESNSEPQKIHISEATKAKVTDLQS-YKISERGHIDIK 1902
            + D L +Q++PK+V + L+  S      E F+EVTI FSD+VGFTTIC    P +VV +LN LY  FD + + H VYKVETIGDAYM+ SG P     +HA  I  ++LD++  +G           + +R+GIH+G   AGVVG KMPRYCLFGDTVNTASRMES   P +IH+S++T   +   QS ++ + RG I++K
Sbjct:  240 RADHLNYQLLPKTVVQALK--SVGSVQPELFEEVTIYFSDIVGFTTICKHCEPMEVVCLLNDLYKEFDSIVDSHDVYKVETIGDAYMLVSGLPKRNGCHHAMEIANVALDILSFMGSFHIQHLPGLPVWVRIGIHSGKCAAGVVGNKMPRYCLFGDTVNTASRMESTGYPYRIHVSQSTVDTLNAQQSGHQFTCRGIIELK 438          

Query:  163 MYGLILEGVRQFICSKYGEDHWNSILRSADIDVITFGTHEVYGETLIPNIIESASRFLNMTVDEIMFLNGIFFINFVSQYGYDGILRVLGRDLRDFLNGLDNLHEYLRFSYPKLKPPSFFCVNESKTGITLQYRTRRSGYIHYVRGQITEIARQFYSTEMSIEIVSQTSEDNVSNCIMRLHFNNKNFIQIE---------------DLLXXXXXXXXXXXXXNIVFNRGMRAINCGKGMLNALPDLPHQLITEYFLLTRPLIEFTWDAVMLHTNNIFELIHLDPKISSSK----------------ILREG---NHSSKKRTLSRNNPSLKMRGQMKYMPEWDAIVFLGTPIMRDVESMYKAGLFINDLSMHDSSRDLVLAGXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMK-KTDELLFQMIPKSVAERLRHGSEAVDTCEHFDEVTILFSDVVGFTTICSKINPFDVVEMLNKLYSVFDELTEKHKVYKVETIGDAYMIASGCPTVTQYHAPFIIEMSLDMIKSIGFLMDPSDHSRSLQIRVGIHTGMVVAGVVGLKMPRYCLFGDTVNTASRMESNSEPQKIHISEATKAKVTDLQSYKISERGHIDIKGKGNIKTYWLDG 1938
            +YGL++E V   + S+YGED W+ I  +A +   TF  H +Y +++   ++ SA        + ++   G  F++F+ Q+GYD ILR+LGR +RDFLNGLDNLHE++RF+YPKLK PSF C  E++ G+ L YR+ R G+++YV GQI E+ + FY  ++ +E++ Q         +M+L+F+N+ FI                  D L +  +VF+EVFPF++V+++ M   + G  +   LP+L    IT+ F L RP ++F+W++V +HTN +FEL      +S  K                 L EG   NH +    ++  +  + ++GQM Y+ EW A+ +L TPI      +     F+          D++L   ++   + L+ + +  +     E   +  +  K +TD LL+QMIPK+VA+RLR G  A++TCE F  VTILFSDVVGFTTICS I P  VV MLN +Y+ FD+L+EKH VYKVETIGDAYM+ SG P  T+YHA  + +M+L+M+ ++  + DP+  +  L+IR+GIHTG VVAGVVGLKMPRYCLFGDTVNTASRMES      IH+SE T+ K     +Y + +RG +DIKGKG +KTYWL G
Sbjct:    2 VYGLLIENVSSLLTSRYGEDTWHKIRENAGVQQHTFAIHNIYSDSIFQRLVSSAEEITGEDRNSLLESTGALFVSFIGQFGYDKILRILGRHIRDFLNGLDNLHEFMRFTYPKLKAPSFHCSEETERGMKLHYRSSRKGFLYYVVGQIREVGKMFYDQQIEVEVLEQHESKEGFVAVMQLYFDNRAFISARKRPKRHSVISLGGETDSLSIHIDVFYEVFPFHVVYDKSMTITSVGSSLEAVLPNLVGCKITDEFSLIRPFLDFSWESVFVHTNVVFELQSRSKALSMRKNGKVQNGLLMGCPIMDALGEGVNGNHDNN-HNVTEFDSRIHLKGQMMYIDEWKAMAYLATPINISTLMLINFTFFLQTYL----DVDVILLFLRKEIRIILSKDVKCMQKSAKLEESMRELDNEKLRTDALLYQMIPKTVADRLRKGEPALNTCETFSNVTILFSDVVGFTTICSLIAPMQVVTMLNCMYTTFDKLSEKHNVYKVETIGDAYMVVSGIPERTKYHAEHVADMALNMLSAMPEIEDPAGLNDHLRIRIGIHTGTVVAGVVGLKMPRYCLFGDTVNTASRMESTGLAMAIHVSEDTQ-KFLAKANYALKQRGSMDIKGKGGMKTYWLLG 622          

Query:  163 MYGLILEGVRQFICSKYGEDHWNSILRSADIDVITFGTHEVYGETLIPNIIESASRFL-----NMTVDEIMFLNGIFFINFVSQYGYDGILRVLGRDLRDFLNGLDNLHEYLRFSYPKLKPPSFFCVNESKTGITLQYRTRRSGYIHYVRGQITEIARQFYS-TEMSIEIV-SQTSEDNVSNC--IMRLHFNNK-------NFIQIEDLLXXXXXXXXXXXXXNIVFNRGMRAINCGKGMLNALPDLP-HQLITEYFLLTRPLIEFTWDAVMLHTNNIFELIHLDPKISSSKILREGNHSSKKRTLSRNNPSLKMRGQMKYMPEWDAIVFLGTPIMRDVESMYKAGLFINDLSMHDSSRDLVLAGXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMKKTDELLFQMIPKSVAERLRHGSEAVDTCEHFDEVTILFSDVVGFTTICSKINPFDVVEMLNKLYSVFDELTEKHKVYKVETIGDA-YMIASGCPTVTQYHAPFIIEMSLDMIKSIGFLMDPSDHSRSLQIRVGIHTGMVVAGVVGLKMPRYCLFGDTVNTASRMESNSEPQKIHISEATKAKVTDLQSYKISERGHIDIK 1902
            MYGL+LE +R FI  KYGE+ W+ I+  A      F TH +Y E  I  I  +A+  L     ++TVD+ M L G+ F+ F S YGYD I+RV GR  RDFL G+D+LHE++RF YPK+K P+F+C  E+ TGI L Y +RR G++ YV GQ+ EIAR+FY  + ++++I+ +++S+ +   C  + RL FNN+       +F+ +     V +EVFF +FPF++V +  M     G G+ + L  L   + I E F+L RP  +FTW   +L    +FEL+   P I   +   +G           +  +L +RGQMK+M +WD  +F+ +P++ ++++M ++GL++NDLSMHD+S+++ L+G +   +L+ A +Q+ E+  +LEE++ KL+E  +++++LL++M+PK +AERL+ G   +DTCE FD  T+LFS + GFT+IC+++N    V ++N L+  FD LTEKH VYK ET+GDA YM  SG P  T++HA  +  M+LDM+K++  + DP    + + I VGIH+G V AG+VG +  +YCLFGDTVN ASR+ + + P +IHISE  +  + +   +    RG I++K
Sbjct:    1 MYGLLLESIRHFIVGKYGEELWSEIVNIAGTSSHEFVTHRLYDENWIFKIANAATTVLGDLDEHITVDDCMRLFGVCFVKFFSFYGYDPIIRVSGRHFRDFLIGIDSLHEHMRFGYPKMKSPTFYCDEETSTGINLHYESRRKGFMFYVVGQVEEIARKFYGISNINVKILKNESSQSSREQCHIVYRLEFNNEGYKPPPPDFLTVGTKKAVSTEVFFSIFPFSLVISPDMTLSMFGNGLQSLLGKLVLGRDIREVFILRRPKTDFTWHT-LLTRKVVFELLSKVPLIRRPQPKHQG-----------STMTLHLRGQMKFMHDWDKFLFICSPLIANLDTMLQSGLYMNDLSMHDTSQEMALSGIKPLPQLEYARDQQFEQGIELEENMRKLEEERQRSEDLLYRMVPKPIAERLKRGGNPIDTCEEFDAATVLFSYMDGFTSICTRLNAMQAVTLINNLFIKFDLLTEKHNVYKFETLGDALYMAVSGVPVRTEHHAEPMAAMALDMLKAVQLVKDPIT-KKPMTITVGIHSGPVAAGLVGERTLQYCLFGDTVNIASRLRTTALPMRIHISENCRECLEE-SDFITEFRGEIELK 584          

Query:  136 VSNY*MLLAMYGLILEGVRQFICSKYGEDHWNSILRSADIDVIT-FGTHEVYGETLIPNIIESASRFLNMTVDEIMFLNGIFFINFVSQYGYDGILRVLGRDLRDFLNGLDNLHEYLRFSYPKLKPPSFFCVN-ESKTGITLQYRTRRSGYIHYVRGQITEIARQFYSTEMSIEIV--SQTSEDNVSNCIMRLHFNN-------KNFIQIEDLLXXXXXXXXXXXX------XNIVFNRGMRAINCGKGMLNALPDL-PHQL-ITEYFLLTRPLIEFTWDAVMLHTNNIFELIHLDPKISSSKILREGNHSSKKR---TLSRNNPSLKMRGQMKYMPEWDAIVFLGTPIMRDVESMYKAGLFINDLSMHDSSRDLVLAGXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMKKTDELLFQMIPKSVAERLRHGSEAVDTCEHFDEVTILFSDVVGFTTICSKINPFDVVEMLNKLYSVFDELTEK--HKVYKVETIGDAYMIASGCPTVTQYHAPFIIEMSLDMIKSIGFLMDPSDHSRSLQIRVGIHTGMVVAGVVGLKMPRYCLFGDTVNTASRMESNSEPQKIHISEATKAKVTDLQ----SYKISERGHIDIKGKGN-IKTYWL 1932
            + +Y + +  YG +   +   +   +G   W  I R+A++++   F    +Y + +  +++ +A+R L++    I+   G  F +F  + GYD IL+VLG  LRDF+  LD LH++L   YP ++ PSF   + ES   + L Y + R G    V G +  +AR+  +TE+S+E+V   +   D+V   I  +           KN+  I+D   + +E             F+++FNR ++    G+ +   +P L P    ++E F L RP + FT++A++ H N +F L     +    K+ +  N+   K     L  ++  L+++GQM Y+PE D ++FL +P + ++E +   GL+++D+ +HD+++DL+L  EQ  AE  L  + E    K  +      ++  + TD+LL+ ++P SVA  LRH        E  + VT+LFS +V F  IC    P ++V +LN +Y+ FD LT+   + VYKVET+GD YM  SG P    +HA  I  M+LDM      ++   D    +QI++GIH+G VVAGVVG K PRYCLFG+TVN  SR E+   P +++I+E T   + + +    S+    RG + +KG+   + TY L
Sbjct:   90 LKHYDLKVLRYGFVNHALELLVVRNFGVAKWEEIKRAAELEIEGHFLQRIIYDDVMTYSLVGAATRVLDIETSAILEKFGEMFFDFCQESGYDRILQVLGGTLRDFIGNLDALHDHLGSIYPGMRAPSFRVSDRESDGALILHYYSERDGLEPIVVGIVKTVARKLLNTEVSVEVVKGKEYDGDDVQFVIKEISDRGRDCDSQVKNYDPIKDSFQLSNEPKISPATFCKAFPFHLMFNRDLKVTQAGESVSRVVPSLTPGDADMSEIFELIRPQLRFTYEAIIAHINTVFVL-----RTREGKLSKPANNMCNKNGCCKLCWDSLPLRLKGQMVYIPESDNMIFLCSPSVGNLEDLADVGLYLSDIPLHDATKDLILLSEQFKAEYVLTQQLEILTDKLRQTHNALAEKK-QLTDQLLYSVLPPSVANELRHNRPV--QAERAEMVTLLFSGIVDFAQICKNSKPMEIVMLLNNIYTKFDMLTDPSINDVYKVETVGDKYMAVSGLPERCAFHARSICNMALDMKHVTQSIIHKGD---KIQIKIGIHSGEVVAGVVGHKTPRYCLFGNTVNLTSRTETTGAPGQVNITEFTYRCLLEPECQDPSFVFERRGPVAMKGRQEPMVTYLL 706          

Query:  163 MYGLILEGVRQFICSKYGEDHWNSILRSADIDV---ITFGTHEVYGETLIPNIIESASRFLNMTVDEIMFLNGIFFINFVSQYGYDGILRVLGRDLRDFLNGLDNLHEYLRFSYPKLKPPSFFCVNES-KTGITLQYRTRRSGYIHYVRGQITEIARQFYSTEMSIEIVSQTSEDN--VSNCIMRLHFNNKNFIQIEDLLXXXXXXXXXXXXXN---------------IVFNRGMRAINCGKGMLNALPDLP--HQLITEYFLLTRPLIEFTWDAVMLHTNNIFELIHLDPKISSSKILREGNHSSKKRTLSRNNPSLKMRGQMKYMPEWDAIVFLGTPIMRDVESMYKAGLFINDLSMHDSSRDLVLAGXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMKKTDELLFQMIPKSVAERLRHGSEAVDTCEHFDEVTILFSDVVGFTTICSKIN-PFDVVEMLNKLYSVFDELTEKHK-VYKVETIGDAYMIASGCPTVTQYHAPFIIEMSLDMIK-SIGFLMDPSDHSRSLQIRVGIHTGMVVAGVVGLKMPRYCLFGDTVNTASRMESNSEPQKIHISEATKAK--VTDLQSYKISERGHIDIKGKGN-IKTYWLDGHNLENPKAVASLIT--QLE 1989
            MYG +   ++  +   YG D W  IL  A++D+     F    +Y +    +++  A   + ++ + I+   G  F       GYD ++R LG +L DF N LD LHE L   YP ++PPSF     +    + L Y + RSG  + V G +  +A + Y  ++++E+ S +S+D       ++  H +   +I   D     +     +   +                VF++ M     G  +   LP +      +T+ F   RP I+ T+D ++ + N ++ +      + S+ +    +  S+    +  +PS++ RGQM Y+PE ++I+FL +P + +++ + + GL+++D+ +HD++RDL+L  EQ +AE KL+   E    K  + S    +E  +  D LL+ ++P SVA  LR           ++ VTI+FS +V FT  C+KI  P ++VEMLN++Y+ FD+LT+ +  +YKVET+GD YM  SG PT    HA  I  ++LDMI  S G           LQ+ +GIH+G VVAGVVG K PRYCLFG+TVN  SR E+     KI++SE       V   + +   +RG + +KGK   + TY L  ++   P      I+  QLE
Sbjct:    1 MYGFVNRALQDLVIQGYGPDVWKEILEKANLDLGDSREFNERRIYDDQNTSDLLIVAEDVIGLSKNAILERFGDAFFEHCIGSGYDSMIRSLGGNLMDFFNSLDGLHEQLLLLYPGMRPPSFRAKQHNINMKLELVYTSERSGLEYMVVGLVKTVASKLYGIQVNVELASMSSKDQSWAMFYVLPQHQDEMKYILPTDTTLERTMKELSIMTLSSRIGTAAFCRACPFHAVFDQRMVIYQAGISLCRVLPAVRVGKSKLTDIFESIRPPIKLTFDNILQYINKVYVIKTKSGLLDSASL----STVSEDDYGNLESPSMRFRGQMMYLPECNSIMFLASPSVVNLDGLNEKGLYMSDIPIHDATRDLILLSEQHNAEFKLSQRLEILTDKLQQTSRELENE-QQLNDRLLYSILPASVANDLRLRKPV--NANKYEIVTIMFSGIVDFTNYCNKIKEPMEIVEMLNEVYTEFDQLTDSNDDIYKVETVGDKYMAVSGLPTRCDKHALNIANLALDMIDISKGM----KAKGIQLQVTIGIHSGEVVAGVVGQKKPRYCLFGNTVNLTSRTETTGLKGKINVSEYAYRCLLVQPHEQFVFKKRGPVVMKGKKEPMITYILQRNDKYQPDGAEQDISLQQLE 629          

Query: 1306 KTDELLFQMIPKSVAERLRHGSEAVDTCEHFDEVTILFSDVVGFTTICSKINPFDVVEMLNKLYSVFDELTEKHKVYKVETIGDAYMIASGCPTVT-QYHAPFIIEMSLDMIK-SIGFLMDPSDHSRSLQIRVGIHTGMVVAGVVGLKMPRYCLFGDTVNTASRMESNSEPQKIHISEATKAKVTDLQSYKISERGHIDIKGKGNIKTYWLDG 1938
            +TDELL  M P+SVAE L+ G +     EHFD VT+ FSD+V FT +C+ I+P  V +MLN +YSVFD+  EK+ VYKVETIGDAYM+ SG P      HA  I  MSLD+++ +    +D     + L +RVGIHTG  V+GVVG KMPRYCLFGDTVNTASRM++   PQK+HISE T   +T   ++ +  RG +++KGKG ++TYWL G
Sbjct:    1 RTDELLSAMFPRSVAETLKLGEKV--PSEHFDSVTVFFSDIVDFTNMCAMISPMSVTQMLNDVYSVFDDHIEKYDVYKVETIGDAYMVVSGLPLRNGTSHADEIGRMSLDLVRLTETTTLDSVPKGKKLMVRVGIHTGPCVSGVVGYKMPRYCLFGDTVNTASRMQTTGIPQKVHISETTYDLLTKFNTFHMEYRGTLEVKGKGLMRTYWLLG 211          

Query:  352 EIMFLNGIFFINFVSQYGYDGILRVL---------GRDLRDFLNGLDNLHEYLRFSYPKLKPPSFFCVNESK-TGITLQYRTRRSGYIHYVRGQITEIARQFYSTEMSIEIVSQTSE--DNVSNCIMRLHFNNKNFIQIEDLLXXXXXXXX--------XXXXXNIVFNRGMRAINCGKGMLNALPDLP--HQLITEYFLLTRPLIEFTWDAVMLHTNNIFELIHLDPKISSSKILREGNHSSKKRTLSRNNPSLKMRGQMKYMPEWDAIVFLGTPIMRDVESMYKAGLFINDLSMHDSSRDLVLAGXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMKKTDELLFQMIPKSVAERLRHGSEAVDTCEHFDEVTILFSDVVGFTTICSK----INPFDVVEMLNKLYSVFDELTEKHK---VYKVETIGDAYMIASGCPTVTQYHAPFIIEMSLDMIKSIGFLMDPSDHSRSLQIRVGIHTGMVVAGVVGLKMPRYCLFGDTVNTASRMESNSEPQKIHISEATK-----AKVTDLQSYKISERGHIDIKGKGNIKTYWL 1932
            EI++L G+  ++ VS      +L+VL              ++ + LD LH++L   YP ++ PSF C +  K   + L Y + R G    V G I  +A+Q + TE+ ++++ Q SE  D++   I       + F +  D                  + FPF+++F++ +    CG  +   LP L     ++   F L RP I+F++  ++ H N +F L   +  ++   +  E   +  + +       L+++GQM Y+PE + I+FL +P + +++ + + GL+++D+ +HD++RDLVL GEQ   E KL  E E    +         DE  KKTD LL+ ++P SVA  LRH        + +D VTILFS +VGF T CSK         +V +LN +Y+ FD LT+  K   VYKVET+GD YM  SG P    +HA  I  ++LDM++  G +    +   S+QI +GIHTG VV GV+G +MPRYCLFG+TVN  SR E+  E  KI++SE T      A+  D Q +++  RG I +KGK      W 
Sbjct:   13 EIIWLFGLL-LHVVSDNRNQALLKVLHGVHDHNLGSVRWTEWFDNLDALHDHLGTIYPGMRAPSFRCTDAEKGNNLILHYYSEREGLQDIVIGIIKTVAQQIHGTEIEMKVIQQKSEECDHIKFLIEEKDSEEEAFNEDLDGFEENGTQETRISPYTFCKAFPFHLMFDKDLMLTQCGNAIYRVLPQLQPGSCILPSVFSLVRPHIDFSFHGILSHINTVFVLRSKEGLLNVETVENEDELTGVEIS------CLRLKGQMIYLPEAENILFLCSPSVMNLDDLTRRGLYLSDIPLHDATRDLVLLGEQFREEYKLTQELEILTDRLQHTLRALEDEK-KKTDRLLYSVLPPSVANELRHKRPV--PAKRYDNVTILFSGIVGFNTFCSKHASAEGAIKIVNLLNDVYTRFDILTDSRKNPYVYKVETVGDKYMTVSGLPEPCTHHAKSICHLALDMMEIAGQVKVDDE---SVQITIGIHTGEVVTGVIGQRMPRYCLFGNTVNLTSRTETTGEKGKINVSEYTYRCLQCAENADPQ-FQLEYRGPITMKGKKEPMKVWF 559          

Query: 1303 KKTDELLFQMIPKSVAERLRHGSEAVDTCEHFDEVTILFSDVVGFTTICSKINPFDVVEMLNKLYSVFDELTEKHKVYKVETIGDAYMIASGCPTVT-QYHAPFIIEMSLDMIKSIGFLMDPSDHSRSLQIRVGIHTGMVVAGVVGLKMPRYCLFGDTVNTASRMESNSEPQKIHISEATKAKVTDLQSYKISERGHIDIKGKGNIKTYWLDGHNLEN 1953
            +K + LL+Q++P SVA++L+ G E V   E FD VTI FSD+VGFT + ++  P  VV +LN LY+ FD + +   VYKVETIGDAYM+ SG P    + H   +  M+L ++ ++         S+ L++R+G+H+G V AGVVGLKMPRYCLFGDTVNTASRMES  E  KIH+SEAT+  + +  ++++  RG I++KGKG+++TYWL G +  N
Sbjct:  780 RKAEALLYQILPHSVADQLKRG-ETVQA-EAFDSVTIYFSDIVGFTALSAESTPLQVVTLLNDLYTCFDAIIDNFDVYKVETIGDAYMVVSGLPVRNGKLHGREVARMALALLDAVKSFKIRHRPSQQLRLRIGVHSGPVCAGVVGLKMPRYCLFGDTVNTASRMESTGEALKIHVSEATRQVLQEFNTFQLQPRGEIEVKGKGHMRTYWLQGEDNSN 995          

Query: 1303 KKTDELLFQMIPKSVAERLRHGSEAVDTCEHFDEVTILFSDVVGFTTICSKINPFDVVEMLNKLYSVFDELTEKHKVYKVETIGDAYMIASGCPTVT-QYHAPFIIEMSLDMIKSIGFLMDPSDHSRSLQIRVGIHTGMVVAGVVGLKMPRYCLFGDTVNTASRMESNSEPQKIHISEATKAKVTDLQSYKISERGHIDIKGKGNIKTYWLDGHNLEN 1953
            +K + LL+Q++P SVA++L+ G E V   E FD VTI FSD+VGFT + ++  P  VV +LN LY+ FD + +   VYKVETIGDAYM+ SG P    + H   +  M+L ++ ++         S+ L++R+G+H+G V AGVVGLKMPRYCLFGDTVNTASRMES  E  KIH+SEAT+  + +  ++++  RG I++KGKG+++TYWL G +  N
Sbjct:  839 RKAEALLYQILPHSVADQLKRG-ETVQA-EAFDSVTIYFSDIVGFTALSAESTPLQVVTLLNDLYTCFDAIIDNFDVYKVETIGDAYMVVSGLPVRNGKLHGREVARMALALLDAVKSFKIRHRPSQQLRLRIGVHSGPVCAGVVGLKMPRYCLFGDTVNTASRMESTGEALKIHVSEATRQVLQEFNTFQLQPRGEIEVKGKGHMRTYWLQGEDNSN 1054          

Query: 1303 KKTDELLFQMIPKSVAERLRHGSEAVDTCEHFDEVTILFSDVVGFTTICSKINPFDVVEMLNKLYSVFDELTEKHKVYKVETIGDAYMIASGCPTVT-QYHAPFIIEMSL---DMIKSIGFLMDPSDHSRSLQIRVGIHTGMVVAGVVGLKMPRYCLFGDTVNTASRMESNSEPQKIHISEATKAKVTDLQSYKISERGHIDIKGKGNIKTYWLDG 1938
            +K + LL+Q++P SVAE+L+ G E V   E FD VTI FSD+VGFT++ ++  P  VV +LN LY+ FD + +   VYKVETIGDAYM+ SG P    + HA  I  MSL   + +K+      P+D    L++R+GIHTG V AGVVGLKMPRYCLFGDTVNTASRMESN E  KIH+S ATK  + +   + +  RG +++KGKG ++TYWL G
Sbjct:  785 RKAENLLYQILPHSVAEQLKRG-ETVQA-EAFDSVTIYFSDIVGFTSMSAESTPLQVVTLLNDLYTCFDAIIDNFDVYKVETIGDAYMVVSGLPVRNGKLHAREIASMSLALLEQVKTFKIRHRPNDQ---LRLRIGIHTGPVCAGVVGLKMPRYCLFGDTVNTASRMESNGEALKIHVSSATKEVLDEFCYFNLELRGDVEMKGKGKMRTYWLLG 995          

Query: 1303 KKTDELLFQMIPKSVAERLRHGSEAVDTCEHFDEVTILFSDVVGFTTICSKINPFDVVEMLNKLYSVFDELTEKHKVYKVETIGDAYMIASGCPTVT-QYHAPFIIEMSLDMIKSIGFLMDPSDHSRSLQIRVGIHTGMVVAGVVGLKMPRYCLFGDTVNTASRMESNSEPQKIHISEATKAKVTDLQ-SYKISERGHIDIKGKGNIKTYWLDGHN 1944
            +KTD L+ QM+PKSVA+ L+ G       EHF EVT+ FSD+VGF+TI +   P +VV++LN LYS+FD +   H VYKVETIGDAYM+ASG PT     HA  I  MSLD++  IG           ++IR+G+H+G VVAGVVGL MPRYCLFGDTVNT SRMES S P ++H++++T   +  L+  YKI  RG  ++KGKG   TYWL G +
Sbjct:  898 QKTDNLVAQMLPKSVAQSLKLGKPV--EPEHFSEVTLYFSDIVGFSTISTLSEPIEVVDLLNDLYSLFDAIIPLHDVYKVETIGDAYMVASGVPTRNGNRHAAEIANMSLDILHCIGTFKARHMPDLKIRIRIGLHSGPVVAGVVGLTMPRYCLFGDTVNTTSRMESTSSPYRVHVNQSTVNLLNSLKLGYKIDVRGLTELKGKGIETTYWLVGKD 1111          

Query:  151 MLLAMYGLILEGVRQFICSKYGEDHWNSILRSADIDVITFGTHEVYGETLIPNIIESASRFLNMTVDEIMFLNGIFFINFVSQYGYDGILRVLGRDLRDFLNGLDNLHEYLRFSYPKLKPPSFFCVNESKTGITLQYRTRRSGYIHYVRGQITEIARQFYSTEMSIEIVSQTSEDNVSNCIMRLHFNNKNFIQIEDLLXXXXXXXXXXXXXNIVFNRGMRAINCGKGMLNALPDLPHQLITEYFLLTRPLIEFTWDAVMLHTNNIFELIHLDPKISSSKILREGNHSSKKRTLSRNNPSLKMRGQMKYMPEWDAIVFLGTPIMRDVESMYKAGLFINDLSMHDSSRDLVLAGXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMKKTDELLFQMIPKSVAERLRHGSEAVDTCEHFDEVTILFSDVVGFTTICSKINPFDVVEMLNKLYSVFDELTEKHKVYKVETIGDAYMIASGCPTVTQYHAPFIIEMSLDMIKSIGFLMDPSDHSRSLQIRVGIHTGMVVAGVVGLKMPRYCLFGDTVNTASRMESNSEPQKIHISEATKAKVTDLQSYKISERGHIDIKGKGNIKTYWLDGHNLENPKAVASLITQLERERITISDSNLAGSQIKGDGWESLTHXXXXXXXXXTGSILELSHTKRLASINHGDSVPGGPEN 2178
            MLLAMYGLILEGVRQFICSKYGEDHWNSILRSADIDVITFGTHEVYGETLIPNIIESASRFLNMTVDEIMFLNGIFFINFVSQYGYDGILRVLGRDLRDFLNGLDNLHEYLRFSYPKLKPPSFFCVNESKTGITLQYRTRRSGYIHYVRGQITEIARQFYSTEMSIEIVSQTSEDNVSNCIMRLHFNNKNFIQIEDLLPVPSEVFFEVFPFNIVFNRGMRAINCGKGMLNALPDLPHQLITEYFLLTRPLIEFTWDAVMLHTNNIFELIHLDPKISSSKILREGNHSSKKRTLSRNNPSLKMRGQMKYMPEWDAIVFLGTPIMRDVESMYKAGLFINDLSMHDSSRDLVLAGEQQSAELKLALEQESEKSKKLEESLHKLDELMKKTDELLFQMIPKSVAERLRHGSEAVDTCEHFDEVTILFSDVVGFTTICSKINPFDVVEMLNKLYSVFDELTEKHKVYKVETIGDAYMIASGCPTVTQYHAPFIIEMSLDMIKSIGFLMDPSDHSRSLQIRVGIHTGMVVAGVVGLKMPRYCLFGDTVNTASRMESNSEPQKIHISEATKAKVTDLQSYKISERGHIDIKGKGNIKTYWLDGHNLENPKAVASLITQLERERITISDSNLAGSQIKGDGWESLTHSRASSARSRTGSILELSHTKRLASINHGDSVPGGPEN
Sbjct:    1 MLLAMYGLILEGVRQFICSKYGEDHWNSILRSADIDVITFGTHEVYGETLIPNIIESASRFLNMTVDEIMFLNGIFFINFVSQYGYDGILRVLGRDLRDFLNGLDNLHEYLRFSYPKLKPPSFFCVNESKTGITLQYRTRRSGYIHYVRGQITEIARQFYSTEMSIEIVSQTSEDNVSNCIMRLHFNNKNFIQIEDLLPVPSEVFFEVFPFNIVFNRGMRAINCGKGMLNALPDLPHQLITEYFLLTRPLIEFTWDAVMLHTNNIFELIHLDPKISSSKILREGNHSSKKRTLSRNNPSLKMRGQMKYMPEWDAIVFLGTPIMRDVESMYKAGLFINDLSMHDSSRDLVLAGEQQSAELKLALEQESEKSKKLEESLHKLDELMKKTDELLFQMIPKSVAERLRHGSEAVDTCEHFDEVTILFSDVVGFTTICSKINPFDVVEMLNKLYSVFDELTEKHKVYKVETIGDAYMIASGCPTVTQYHAPFIIEMSLDMIKSIGFLMDPSDHSRSLQIRVGIHTGMVVAGVVGLKMPRYCLFGDTVNTASRMESNSEPQKIHISEATKAKVTDLQSYKISERGHIDIKGKGNIKTYWLDGHNLENPKAVASLITQLERERITISDSNLAGSQIKGDGWESLTHSRASSARSRTGSILELSHTKRLASINHGDSVPGGPEN 676          

Query:  163 MYGLILEGVRQFICSKYGEDHWNSILRSADIDVITFGTHEVYGETLIPNIIESASRFLNMTVDEIMFLNGIFFINFVSQYGYDGILRVLGRDLRDFLNGLDNLHEYLRFSYPKLKPPSFFCVNESKTGITLQYRTRRSGYIHYVRGQITEIARQFYSTEMSIEIVSQTSEDNVSNCIMRLHFNNKNFIQIEDLLXXXXXXXXXXXXXNIVFNRGMRAINCGKGMLNALPDLPHQLITEYFLLTRPLIEFTWDAVMLHTNNIFELIHLDPKISSSKILREGNHSSKKRTLSRNNPSLKMRGQMKYMPEWDAIVFLGTPIMRDVESMYKAGLFINDLSMHDSSRDLVLAGXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMKKTDELLFQMIPKSVAERLRHGSEAVDTCEHFDEVTILFSDVVGFTTICSKINPFDVVEMLNKLYSVFDELTEKHKVYKVETIGDAYMIASGCPTVTQYHAPFIIEMSLDMIKSIGFLMDPSDHSRSLQIRVGIHTGMVVAGVVGLKMPRYCLFGDTVNTASRMESNSEPQKIHISEATKAKVTDLQSYKISERGHIDIKGKGNIKTYWLDGHNLENPKAVASLITQLERERITISDSNLAGSQIKGDGWESLTHXXXXXXXXXTGSILELSHTKRLASINHGDSVPGGPEN 2178
            MYGLILEGVRQFICSKYGEDHWNSILRSADIDVITFGTHEVYGETLIPNIIESASRFLNMTVDEIMFLNGIFFINFVSQYGYDGILRVLGRDLRDFLNGLDNLHEYLRFSYPKLKPPSFFCVNESKTGITLQYRTRRSGYIHYVRGQITEIARQFYSTEMSIEIVSQTSEDNVSNCIMRLHFNNKNFIQIEDLLPVPSEVFFEVFPFNIVFNRGMRAINCGKGMLNALPDLPHQLITEYFLLTRPLIEFTWDAVMLHTNNIFELIHLDPKISSSKILREGNHSSKKRTLSRNNPSLKMRGQMKYMPEWDAIVFLGTPIMRDVESMYKAGLFINDLSMHDSSRDLVLAGEQQSAELKLALEQESEKSKKLEESLHKLDELMKKTDELLFQMIPKSVAERLRHGSEAVDTCEHFDEVTILFSDVVGFTTICSKINPFDVVEMLNKLYSVFDELTEKHKVYKVETIGDAYMIASGCPTVTQYHAPFIIEMSLDMIKSIGFLMDPSDHSRSLQIRVGIHTGMVVAGVVGLKMPRYCLFGDTVNTASRMESNSEPQKIHISEATKAKVTDLQSYKISERGHIDIKGKGNIKTYWLDGHNLENPKAVASLITQLERERITISDSNLAGSQIKGDGWESLTHSRASSARSRTGSILELSHTKRLASINHGDSVPGGPEN
Sbjct:    1 MYGLILEGVRQFICSKYGEDHWNSILRSADIDVITFGTHEVYGETLIPNIIESASRFLNMTVDEIMFLNGIFFINFVSQYGYDGILRVLGRDLRDFLNGLDNLHEYLRFSYPKLKPPSFFCVNESKTGITLQYRTRRSGYIHYVRGQITEIARQFYSTEMSIEIVSQTSEDNVSNCIMRLHFNNKNFIQIEDLLPVPSEVFFEVFPFNIVFNRGMRAINCGKGMLNALPDLPHQLITEYFLLTRPLIEFTWDAVMLHTNNIFELIHLDPKISSSKILREGNHSSKKRTLSRNNPSLKMRGQMKYMPEWDAIVFLGTPIMRDVESMYKAGLFINDLSMHDSSRDLVLAGEQQSAELKLALEQESEKSKKLEESLHKLDELMKKTDELLFQMIPKSVAERLRHGSEAVDTCEHFDEVTILFSDVVGFTTICSKINPFDVVEMLNKLYSVFDELTEKHKVYKVETIGDAYMIASGCPTVTQYHAPFIIEMSLDMIKSIGFLMDPSDHSRSLQIRVGIHTGMVVAGVVGLKMPRYCLFGDTVNTASRMESNSEPQKIHISEATKAKVTDLQSYKISERGHIDIKGKGNIKTYWLDGHNLENPKAVASLITQLERERITISDSNLAGSQIKGDGWESLTHSRASSARSRTGSILELSHTKRLASINHGDSVPGGPEN 672          

Query:  163 MYGLILEGVRQFICSKYGEDHWNSILRSADIDVITFGTHEVYGETLIPNIIESASRFLNMTVDEIMFLNGIFFINFVSQYGYDGILRVLGRDLRDFLNGLDNLHEYLRFSYPKLKPPSFFCVNESKTGITLQYRTRRSGYIHYVRGQITEIARQFYSTEMSIEIVSQTSEDN-VSNCIMRLHFNNKNFIQIEDLLXXXXXXXXXXXXXNIVFNRGMRAINCGKGMLNALPDLPHQLITEYFLLTRPLIEFTWDAVMLHTNNIFELIHLDPKISSSKILREGNHSSKKRTLSRNNPSLKMRGQMKYMPEWDAIVFLGTPIMRDVESMYKAGLFINDLSMHDSSRDLVLAGXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMKKTDELLFQMIPKSVAERLRHGSEAVDTCEHFDEVTILFSDVVGFTTICSKINPFDVVEMLNKLYSVFDELTEKHKVYKVETIGDAYMIASGCPTVTQYHAPFIIEMSLDMIKSIGFLMDPSDHSRSLQIRVGIHTGMVVAGVVGLKMPRYCLFGDTVNTASRMESNSEPQKIHISEATKAKVTDLQSYKISERGHIDIKGKGNIKTYWLDGHNLENPKAVASLITQLERERITISDSNLAGSQIKGDGWESLT 2064
            MYGL+LEG+RQFICS YG   W  IL  + +DV  F  HEVY E L+  I+ +A+ +  +T DE+MF NG +FI+F+S YGYD ILRVLGRDLRDFLNGLDNLHEYLRFSYPKLKPPSFFCVNES+TGITLQYRT+R+G++HYVRGQI EIA+ FY+T + IEI+ +    N V NC                             PFNIVFNRG+R +NCG+GM N +PD+    + + F + RP+I+ +WD ++LH+NN+FELI L  K S          S    +L  +N  L+MRGQMKYM EWDAIVFLGTPIMRDVESM+KAGL+INDLSMHDSSRDLVLAGEQQSAEL+LALEQESEKSK+LE+SL +LD+ M++TDELL+QMIP++VA RLR+G ++V+TCE F+EVTILFSDVVGFT ICS I P DVVEMLN +YSVFD+LTE+HKVYKVET+GDAYMIASGCP +T  +AP I EM+L+MI  I  + +P++   SL+IRVGIHTG VVAGVVG+KMPRYCLFGDTVNTASRMES  E QKI IS +T+ K+     Y+I ERG +++KGKGN+ TYWL+ H  +    + + +  + +ER  + D+N++  Q  G+ W  L+
Sbjct:    1 MYGLLLEGIRQFICSTYGLQAWTQILEKSKLDVNVFAIHEVYDEELLKRIVFTAADYCRITKDELMFQNGKYFISFLSHYGYDSILRVLGRDLRDFLNGLDNLHEYLRFSYPKLKPPSFFCVNESRTGITLQYRTQRAGFVHYVRGQIFEIAKTFYNTTIEIEIIGENKMPNKVFNCF----------------------------PFNIVFNRGLRVVNCGRGMRNLIPDIIGDYVGDVFHVNRPIIQISWDTIILHSNNVFELILLHIKKSRLSD------SDSSNSLKESNYRLRMRGQMKYMNEWDAIVFLGTPIMRDVESMWKAGLYINDLSMHDSSRDLVLAGEQQSAELRLALEQESEKSKRLEDSLKRLDDEMRRTDELLYQMIPRAVANRLRNGEKSVNTCETFNEVTILFSDVVGFTKICSNITPLDVVEMLNSMYSVFDQLTERHKVYKVETVGDAYMIASGCPVLTTLNAPLIAEMALEMIDKICTIKNPANEIESLKIRVGIHTGTVVAGVVGIKMPRYCLFGDTVNTASRMESTGETQKIQISSSTQKKLMMHNVYQIVERGVVEVKGKGNVSTYWLEKHLDKQSLGLLNYMETVTKERERLGDANMSTYQSHGEYWHELS 601          

Query:  163 MYGLILEGVRQFICSKYGEDHWNSILRSADIDVITFGTHEVYGETLIPNIIESASRFLNMTVDEIMFLNGIFFINFVSQYGYDGILRVLGRDLRDFLNGLDNLHEYLRFSYPKLKPPSFFCVNESKTGITLQYRTRRSGYIHYVRGQITEIARQFYSTEMSIEIVSQTSEDNVSNCIMRLHFNNKNFIQIEDL------LXXXXXXXXXXXXXNIVFNRGMRAINCGKGMLNALPDLPHQLITEYFLLTRPLIEFTWDAVMLHTNNIFELIHLDPKISSSKI--LREGNHSSKKRTLSRNNPSLKMRGQMKYMPEWDAIVFLGTPIMRDVESMYKAGLFINDLSMHDSSRDLVLAGXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMKKTDELLFQMIPKSVAERLRHGSEAVDTCEHFDEVTILFSDVVGFTTICSKINPFDVVEMLNKLYSVFDELTEKHKVYKVETIGDAYMIASGCPTVTQYHAPFIIEMSLDMIK-SIGFLMDPSDHSRSLQIRVGIHTGMVVAGVVGLKMPRYCLFGDTVNTASRMESNSEPQKIHISEATKAKVTDLQSYKISERGHIDIKGKGNIKTYWLDGHNLENPKAVASLITQLERERITISDS 2016
            MYGL++  ++ F+ S YG D W   L  A+ID  +  TH VY ET+IP I+ + S  LN   ++IMF NG +F+ ++S  GYD ILRVLGR+  DF+ GLDNLHEYLRFSYPK+KPPSF   + +++ I L YRT+R G+ HYVRGQ+  IA+ FY  ++ I ++S+  +   ++    +  + K F +  ++       P+  ++FFE+FPF++V +  +   +CG G  +  P L +    + F+L++P I+ T++ ++ + N+ FE+I L P  SS  +    + + ++ KR  S     +K +GQM  MP W+ ++FLGTP++RDV+ + +AGLF+NDL+  D+ +D++LAG QQS EL    E++ EKSK+LEE++  L++  KKTDELL+Q IPKS+A+RLR G  ++DTC+ F  V+I FS VV F  ICS+I+   +V +LN +Y+ FD LTE +KVYKVETI D+YM+ SG P+ T  H+  I+EM+L MI  +   L +P+  S S+++ +G H+GM+VAG+VG+KMPRYCLFGDTVNT+SRM S+  P K+H+S+     ++    Y  ++RG ++IKGKG++ TY+++     +   V     +LE +R+   DS
Sbjct:    1 MYGLLVGALQHFVESLYGADIWIQALNLAEIDYQSINTHSVYAETIIPRIVNALSSILNEAEEDIMFHNGCYFVEYLSTCGYDKILRVLGRNFVDFIQGLDNLHEYLRFSYPKIKPPSFNVESVTESTIKLHYRTKRPGFQHYVRGQLVNIAKYFYEKDIKIFLISKIEDSYQTHYTFDILLDMKGFEKTLEISIPYENFPIRRDMFFEIFPFHLVLSENLTIQHCGVGFKHICPTLLNSNFNDEFILSKPFIDATYEKIVRYNNSNFEII-LMPHTSSGPLNAALKKDKANIKRLSSIVQGRIKFKGQMLDMPLWNGLMFLGTPVIRDVKQLKEAGLFLNDLNKFDTGKDIILAGSQQSDELMELFEKQLEKSKQLEENMRDLNKFRKKTDELLYQCIPKSIAKRLRKGVSSMDTCQVFQSVSICFSKVVDFVQICSEISVDKIVNLLNDMYTHFDNLTELYKVYKVETISDSYMLVSGAPSTTDLHSAHIVEMALSMITCAKKNLKNPAKSSGSIELLIGCHSGMIVAGIVGIKMPRYCLFGDTVNTSSRMMSHGSPNKVHVSDIFFEHISQF-PYNYTKRGEMEIKGKGSMTTYFIESRKSGDEYKV--FKQKLEEDRLMHDDS 623          

Query:  163 MYGLILEGVRQFICSKYGEDHWNSILRSADIDVITFGTHEVYGETLIPNIIESASRFLNMTVDEIMFLNGIFFINFVSQYGYDGILRVLGRDLRDFLNGLDNLHEYLRFSYPKLKPPSFFCVNESKTGITLQYRTRRSGYIHYVRGQITEIARQFYSTEMSIEIVSQTSEDNVSNCIMRLHFNNKNFIQIEDL------LXXXXXXXXXXXXXNIVFNRGMRAINCGKGMLNALPDLPHQLITEYFLLTRPLIEFTWDAVMLHTNNIFELIHLDPKISSSKI--LREGNHSSKKRTLSRNNPSLKMRGQMKYMPEWDAIVFLGTPIMRDVESMYKAGLFINDLSMHDSSRDLVLAGXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMKKTDELLFQMIPKSVAERLRHGSEAVDTCEHFDEVTILFSDVVGFTTICSKINPFDVVEMLNKLYSVFDELTEKHKVYKVETIGDAYMIASGCPTVTQYHAPFIIEMSLDMIK-SIGFLMDPSDHSRSLQIRVGIHTGMVVAGVVGLKMPRYCLFGDTVNTASRMESNSEPQKIHISEATKAKVTDLQSYKISERGHIDIKGKGNIKTYWLDGHNLENPKAVASLITQLERERITISDS 2016
            MYGL++  ++ F+ S YG D W   L  A+ID  +  TH VY ET+IP I+ + S  LN   ++IMF NG +F+ ++S  GYD ILRVLGR+  DF+ GLDNLHEYLRFSYPK+KPPSF   + +++ I L YRT+R G+ HYVRGQ+  IA+ FY  ++ I ++S+  +   ++    +  + K F +  ++       P+  ++FFE+FPF++V +  +   +CG G  +  P L +    + F+L++P I+ T++ ++ + N+ FE+I L P  SS  +    + + ++ KR  S     +K +GQM  MP W+ ++FLGTP++RDV+ + +AGLF+NDL+  D+ +D++LAG QQS EL    E++ EKSK+LEE++  L++  KKTDELL+Q IPKS+A+RLR G  ++DTC+ F  V+I FS VV F  ICS+I+   +V +LN +Y+ FD LTE +KVYKVETI D+YM+ SG P+ T  H+  I+EM+L MI  +   L +P+  S S+++ +G H+GM+VAG+VG+KMPRYCLFGDTVNT+SRM S+  P K+H+S+     ++    Y  ++RG ++IKGKG++ TY+++     +   V     +LE +R+   DS
Sbjct:    1 MYGLLVGALQHFVESLYGADIWIQALNLAEIDYQSINTHSVYAETIIPRIVNALSSILNEAEEDIMFHNGCYFVEYLSTCGYDKILRVLGRNFVDFIQGLDNLHEYLRFSYPKIKPPSFNVESVTESTIKLHYRTKRPGFQHYVRGQLVNIAKYFYEKDIKIFLISKIEDSYQTHYTFDILLDMKGFEKTLEISIPYENFPIRRDMFFEIFPFHLVLSENLTIQHCGVGFKHICPTLLNSNFNDEFILSKPFIDATYEKIVRYNNSNFEII-LMPHTSSGPLNAALKKDKANIKRLSSIVQGRIKFKGQMLDMPLWNGLMFLGTPVIRDVKQLKEAGLFLNDLNKFDTGKDIILAGSQQSDELMELFEKQLEKSKQLEENMRDLNKFRKKTDELLYQCIPKSIAKRLRKGVSSMDTCQVFQSVSICFSKVVDFVQICSEISVDKIVNLLNDMYTHFDNLTELYKVYKVETISDSYMLVSGAPSTTDLHSAHIVEMALSMITCAKKNLKNPAKSSGSIELLIGCHSGMIVAGIVGIKMPRYCLFGDTVNTSSRMMSHGSPNKVHVSDIFFEHISQF-PYNYTKRGEMEIKGKGSMTTYFIESRKSGDEYKV--FKQKLEEDRLMHDDS 623