Protein NDRG4

Overview


Name	Protein NDRG4
Smed ID	SMED30013306
Length (bp)	1127

Neoblast Clusters

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Overview

Single cell RNA-seq of pluripotent neoblasts and its early progenies

We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)

Explore this single cell expression dataset with our NB Cluster Shiny App

Neoblast Population

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.

Expression of Protein NDRG4 (SMED30013306) t-SNE clustered cells

Violin plots show distribution of expression levels for Protein NDRG4 (SMED30013306) in cells (dots) of each of the 12 neoblast clusters.

Sub-lethal Irradiated Surviving X1 and X2 Cell Population

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of Protein NDRG4 (SMED30013306) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for Protein NDRG4 (SMED30013306) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

Anatomical Expression

PAGE et. al., 2020

SMED30013306

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE

PAGE Curations: 5

Expressed In	Reference Transcript	Gene Models	Published Transcript	Transcriptome	Publication
nervous system	SMED30013306	SMESG000055233.1 SMESG000055204.1	dd_Smed_v4_11017_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
cephalic ganglia	SMED30013306	SMESG000055233.1 SMESG000055204.1	dd_Smed_v4_11017_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
neuron	SMED30013306	SMESG000055233.1 SMESG000055204.1	dd_Smed_v4_11017_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
cilated neuron	SMED30013306	SMESG000055233.1 SMESG000055204.1	dd_Smed_v4_11017_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
head region	SMED30013306	SMESG000055233.1 SMESG000055204.1	dd_Smed_v6_11017_0_1	dd_Smed_v6	PMID:28171748 Stückemann et al., 2017

Note: Hover over icons to view figure legend

Homology

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BLAST of Protein NDRG4 vs. Ensembl Human
Match: NDRG1 (N-myc downstream regulated 1 [Source:HGNC Symbol;Acc:HGNC:7679])

HSP 1 Score: 113.235 bits (282), Expect = 1.706e-27
Identity = 75/287 (26.13%), Postives = 135/287 (47.04%), Query Frame = 2

Query:   77 GVLNIYIQGNRSPNEVIIFTIHDLGCNHKE-YEQFLEHTSMKHLRNRCVWIHLDIPGQGDNDEDLNLKE-FPTMQEIADDIKVIFDELNIQHAVLFGEGAGANILARFAMNNDDKVLGIVLIHCTGTTAGIKEAIRDRLITWKLNTTGMNPVAESYLVVHRFG-EHINTNSEKEFREMINGFKRNLQASINPRNLNKFILSFMNRSNI-------AERIYQLKCPALFVTGNLASHNHTVMTLYNTLQKFVKDDPERIKKLELIQVNGVANVLKEKPEKIAESLQYF 907
            G +++ + G    N  +I T HD+G NHK  Y     +  M+ +       H+D PGQ D          +P+M ++A+ +  +  +  ++  +  G GAGA IL RFA+NN + V G+VLI+      G  +    ++  W      M       +V H FG E + +N      E+++ +++++   +NP NL+ FI ++ +R ++             L+CPAL V G+ +     V+   + L      DP +   L++    G+  +   +P K+AE+ +YF
Sbjct:   42 GSVHVTLCGTPKGNRPVILTYHDIGMNHKTCYNPLFNYEDMQEITQHFAVCHVDAPGQQDGAASFPAGYMYPSMDQLAEMLPGVLQQFGLKSIIGMGTGAGAYILTRFALNNPEMVEGLVLINVNPCAEGWMDWAASKISGWTQALPDM-------VVSHLFGKEEMQSNV-----EVVHTYRQHIVNDMNPGNLHLFINAYNSRRDLEIERPMPGTHTVTLQCPALLVVGDSSPAVDAVVECNSKL------DPTKTTLLKMADCGGLPQI--SQPAKLAEAFKYF 308

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Query:   77 GVLNIYIQGNRSPNEVIIFTIHDLGCNHKE-YEQFLEHTSMKHLRNRCVWIHLDIPGQGDNDEDLNLKE-FPTMQEIADDIKVIFDELNIQHAVLFGEGAGANILARFAMNNDDKVLGIVLIHCTGTTAGIKEAIRDRLITWKLNTTGMNPVAESYLVVHRFG-EHINTNSEKEFREMINGFKRNLQASINPRNLNKFILSFMNRSNI-------AERIYQLKCPALFVTGNLASHNHTVMTLYNTLQKFVKDDPERIKKLELIQVNGVANVLKEKPEKIAESLQYF 907
            G +++ + G    N  +I T HD+G NHK  Y     +  M+ +       H+D PGQ D          +P+M ++A+ +  +  +  ++  +  G GAGA IL RFA+NN + V G+VLI+      G  +    ++  W      M       +V H FG E + +N      E+++ +++++   +NP NL+ FI ++ +R ++             L+CPAL V G+ +     V+   + L      DP +   L++    G+  +   +P K+AE+ +YF
Sbjct:   42 GSVHVTLCGTPKGNRPVILTYHDIGMNHKTCYNPLFNYEDMQEITQHFAVCHVDAPGQQDGAASFPAGYMYPSMDQLAEMLPGVLQQFGLKSIIGMGTGAGAYILTRFALNNPEMVEGLVLINVNPCAEGWMDWAASKISGWTQALPDM-------VVSHLFGKEEMQSNV-----EVVHTYRQHIVNDMNPGNLHLFINAYNSRRDLEIERPMPGTHTVTLQCPALLVVGDSSPAVDAVVECNSKL------DPTKTTLLKMADCGGLPQI--SQPAKLAEAFKYF 308

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BLAST of Protein NDRG4 vs. Ensembl Human
Match: NDRG2 (NDRG family member 2 [Source:HGNC Symbol;Acc:HGNC:14460])

HSP 1 Score: 101.679 bits (252), Expect = 7.022e-24
Identity = 79/289 (27.34%), Postives = 134/289 (46.37%), Query Frame = 2

Query:   59 VTTPKCGVLNIYIQGNRSPNEVIIFTIHDLGCNHKE-YEQFLEHTSMKHLRNRCVWIHLDIPGQGDNDEDLNLK-EFPTMQEIADDIKVIFDELNIQHAVLFGEGAGANILARFAMNNDDKVLGIVLIHCTGTTAGIKEAIRDRLITWKLNTTGMNPVAESYLVVHRFG-EHINTNSEKEFREMINGFKRNLQASINPRNLNKFILSFMNRSNI-AER--IYQLKCPALFVTGNLASHNHTVMTLYNTLQKFVKDDPERIKKLELIQVNGVANVLKEKPEKIAESLQYF 907
            V TP  G +   + G   P    I T HD+G N+K  ++   +   M+ +    V +H+D PG  +      L  ++P++ ++AD I  +   LN    +  G GAGA ILAR+A+N+ D V G+VLI+      G  +    +L       TG+       ++ H F  E ++ NS     E+I  ++  +  + N  N+  +  S+ NR ++  ER     L+CP + V G+ A H   V+   + L      DP +   L++    G   +   +P K+ E+ +YF
Sbjct:   29 VETPY-GSVTFTVYGTPKPKRPAILTYHDVGLNYKSCFQPLFQFEDMQEIIQNFVRVHVDAPGMEEGAPVFPLGYQYPSLDQLADMIPCVLQYLNFSTIIGVGVGAGAYILARYALNHPDTVEGLVLINIDPNAKGWMDWAAHKL-------TGLTSSIPEMILGHLFSQEELSGNS-----ELIQKYRNIITHAPNLDNIELYWNSYNNRRDLNFERGGDITLRCPVMLVVGDQAPHEDAVVECNSKL------DPTQTSFLKMADSGGQPQL--TQPGKLTEAFKYF 296

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BLAST of Protein NDRG4 vs. Ensembl Human
Match: NDRG2 (NDRG family member 2 [Source:HGNC Symbol;Acc:HGNC:14460])

HSP 1 Score: 101.679 bits (252), Expect = 1.632e-23
Identity = 79/293 (26.96%), Postives = 135/293 (46.08%), Query Frame = 2

Query:   47 EVKQVTTPKCGVLNIYIQGNRSPNEVIIFTIHDLGCNHKE-YEQFLEHTSMKHLRNRCVWIHLDIPGQGDNDEDLNLK-EFPTMQEIADDIKVIFDELNIQHAVLFGEGAGANILARFAMNNDDKVLGIVLIHCTGTTAGIKEAIRDRLITWKLNTTGMNPVAESYLVVHRFG-EHINTNSEKEFREMINGFKRNLQASINPRNLNKFILSFMNRSNI-AERI--YQLKCPALFVTGNLASHNHTVMTLYNTLQKFVKDDPERIKKLELIQVNGVANVLKEKPEKIAESLQYF 907
            +   V TP  G +   + G   P    I T HD+G N+K  ++   +   M+ +    V +H+D PG  +      L  ++P++ ++AD I  +   LN    +  G GAGA ILAR+A+N+ D V G+VLI+      G  +    +L       TG+       ++ H F  E ++ NS     E+I  ++  +  + N  N+  +  S+ NR ++  ER     L+CP + V G+ A H   V+   + L      DP +   L++    G   +   +P K+ E+ +YF
Sbjct:   39 QTHSVETPY-GSVTFTVYGTPKPKRPAILTYHDVGLNYKSCFQPLFQFEDMQEIIQNFVRVHVDAPGMEEGAPVFPLGYQYPSLDQLADMIPCVLQYLNFSTIIGVGVGAGAYILARYALNHPDTVEGLVLINIDPNAKGWMDWAAHKL-------TGLTSSIPEMILGHLFSQEELSGNS-----ELIQKYRNIITHAPNLDNIELYWNSYNNRRDLNFERGGDITLRCPVMLVVGDQAPHEDAVVECNSKL------DPTQTSFLKMADSGGQPQL--TQPGKLTEAFKYF 310

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Query:   47 EVKQVTTPKCGVLNIYIQGNRSPNEVIIFTIHDLGCNHKE-YEQFLEHTSMKHLRNRCVWIHLDIPGQGDNDEDLNLK-EFPTMQEIADDIKVIFDELNIQHAVLFGEGAGANILARFAMNNDDKVLGIVLIHCTGTTAGIKEAIRDRLITWKLNTTGMNPVAESYLVVHRFG-EHINTNSEKEFREMINGFKRNLQASINPRNLNKFILSFMNRSNI-AERI--YQLKCPALFVTGNLASHNHTVMTLYNTLQKFVKDDPERIKKLELIQVNGVANVLKEKPEKIAESLQYF 907
            +   V TP  G +   + G   P    I T HD+G N+K  ++   +   M+ +    V +H+D PG  +      L  ++P++ ++AD I  +   LN    +  G GAGA ILAR+A+N+ D V G+VLI+      G  +    +L       TG+       ++ H F  E ++ NS     E+I  ++  +  + N  N+  +  S+ NR ++  ER     L+CP + V G+ A H   V+   + L      DP +   L++    G   +   +P K+ E+ +YF
Sbjct:   39 QTHSVETPY-GSVTFTVYGTPKPKRPAILTYHDVGLNYKSCFQPLFQFEDMQEIIQNFVRVHVDAPGMEEGAPVFPLGYQYPSLDQLADMIPCVLQYLNFSTIIGVGVGAGAYILARYALNHPDTVEGLVLINIDPNAKGWMDWAAHKL-------TGLTSSIPEMILGHLFSQEELSGNS-----ELIQKYRNIITHAPNLDNIELYWNSYNNRRDLNFERGGDITLRCPVMLVVGDQAPHEDAVVECNSKL------DPTQTSFLKMADSGGQPQL--TQPGKLTEAFKYF 310

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BLAST of Protein NDRG4 vs. Ensembl Celegans
Match: ZK1073.1 (pep chromosome:WBcel235:X:16124151:16128865:-1 gene:WBGene00014213.1 transcript:ZK1073.1.2 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:ZK1073.1)

HSP 1 Score: 221.09 bits (562), Expect = 2.165e-69
Identity = 118/319 (36.99%), Postives = 195/319 (61.13%), Query Frame = 2

Query:   59 VTTPKCGVLNIYIQGN--RSPNEVIIFTIHDLGCNHKEYEQFLEHTSMKHLRNRCVWIHLDIPGQGDNDEDLNLKEFPTMQEIADDIKVIFDELNIQHAVLFGEGAGANILARFAMNNDDKVLGIVLIHCTGTTAGIKEAIRDRLITWKLNTTGMNPVAESYLVVHRFGEHINTNSEKEFREMINGFKRNLQASINPRNLNKFILSFMNRSNIAERIYQL--KCPALFVTGNLASHNHTVMTLYNTLQKFVKDDPERIKKLELIQVNGVANVLKEKPEKIAESLQYFXXXXXXXXXXRVHSLCNPLSRRLSMEQLDLPR 1003
            V    CGVL++Y+QGN      + II T+HD+G NHK + +F+ H SM  ++ + +++H+ +PGQ DN  D    +FPT+  I DD+  + D+  ++ A+ FGEG GANI+ RFAM + ++++GIVL+HCT TTAGI E  +++++  +L  + M+  A  YL+ H+FG    + S +E+ E        L+A++NP+NL+K++++F  R++++  I        AL VTG+ ASH HTV T + ++ K         KK  L+ V+ VA+V++E P+K+A SL    +G G++ G+ +  +    +   SME+ D PR
Sbjct:   11 VQAQNCGVLHVYVQGNLEERGGKTIILTVHDIGTNHKSFVRFVNHPSMATVKEKAIFLHVCVPGQEDNSADF-FGDFPTLDGIGDDLSAVLDKFEVKSAIAFGEGVGANIICRFAMGHPNRIMGIVLVHCTSTTAGIIEYCKEKVMNMRLENSIMSDGAWDYLLAHKFGG--ESKSRQEYLE-------ELKATLNPKNLSKYLVAFTKRTDLSSTIGTKLETVDALLVTGSKASHLHTVYTTHKSMNK---------KKTTLLVVDNVADVMQEAPDKLARSLILLCKGCGVLSGVAIPGMERQRTLSSSMEEADRPR 310

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BLAST of Protein NDRG4 vs. Ensembl Celegans
Match: ZK1073.1 (pep chromosome:WBcel235:X:16123942:16128815:-1 gene:WBGene00014213.1 transcript:ZK1073.1.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:ZK1073.1)

HSP 1 Score: 221.09 bits (562), Expect = 2.165e-69
Identity = 118/319 (36.99%), Postives = 195/319 (61.13%), Query Frame = 2

Query:   59 VTTPKCGVLNIYIQGN--RSPNEVIIFTIHDLGCNHKEYEQFLEHTSMKHLRNRCVWIHLDIPGQGDNDEDLNLKEFPTMQEIADDIKVIFDELNIQHAVLFGEGAGANILARFAMNNDDKVLGIVLIHCTGTTAGIKEAIRDRLITWKLNTTGMNPVAESYLVVHRFGEHINTNSEKEFREMINGFKRNLQASINPRNLNKFILSFMNRSNIAERIYQL--KCPALFVTGNLASHNHTVMTLYNTLQKFVKDDPERIKKLELIQVNGVANVLKEKPEKIAESLQYFXXXXXXXXXXRVHSLCNPLSRRLSMEQLDLPR 1003
            V    CGVL++Y+QGN      + II T+HD+G NHK + +F+ H SM  ++ + +++H+ +PGQ DN  D    +FPT+  I DD+  + D+  ++ A+ FGEG GANI+ RFAM + ++++GIVL+HCT TTAGI E  +++++  +L  + M+  A  YL+ H+FG    + S +E+ E        L+A++NP+NL+K++++F  R++++  I        AL VTG+ ASH HTV T + ++ K         KK  L+ V+ VA+V++E P+K+A SL    +G G++ G+ +  +    +   SME+ D PR
Sbjct:   11 VQAQNCGVLHVYVQGNLEERGGKTIILTVHDIGTNHKSFVRFVNHPSMATVKEKAIFLHVCVPGQEDNSADF-FGDFPTLDGIGDDLSAVLDKFEVKSAIAFGEGVGANIICRFAMGHPNRIMGIVLVHCTSTTAGIIEYCKEKVMNMRLENSIMSDGAWDYLLAHKFGG--ESKSRQEYLE-------ELKATLNPKNLSKYLVAFTKRTDLSSTIGTKLETVDALLVTGSKASHLHTVYTTHKSMNK---------KKTTLLVVDNVADVMQEAPDKLARSLILLCKGCGVLSGVAIPGMERQRTLSSSMEEADRPR 310

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BLAST of Protein NDRG4 vs. Ensembl Celegans
Match: Y48G10A.3 (pep chromosome:WBcel235:I:13471683:13474185:-1 gene:WBGene00013020.1 transcript:Y48G10A.3.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:Y48G10A.3)

HSP 1 Score: 112.079 bits (279), Expect = 9.932e-28
Identity = 76/285 (26.67%), Postives = 141/285 (49.47%), Query Frame = 2

Query:   77 GVLNIYIQGNRS-PNEVIIFTIHDLGCNHKE-YEQFLEHTSMKHLRNRCVWIHLDIPGQGDNDEDLNLK-EFPTMQEIADDIKVIFDELNIQHAVLFGEGAGANILARFAMNNDDKVLGIVLIHCTGTTAGIKEAIRDRLITWKLNTTGMNPVAESYLVVHRFGEHINTNSEKEFREMINGFKRNLQASINPRNLNKFILSFMNRSNI-----AERIYQLKCPALFVTGNLASHNHTVMTLYNTLQKFVKDDPERIKKLELIQVNGVANVLKEKPEKIAESLQYF 907
            G + + I G+R+ P +V + T HDLG + +  ++ F +  S+    ++    +++ PGQ  + + L     +PTM  IA  I+ + D   +   + FG G GAN+L R+A  N ++V+ +VL++C    +G  E   ++  T  L   GM      YL+ H FG + +  S     +++  ++   Q   NP +L +FI S++ R+ +          QLK P L + G  ++H      + +T++   K DP     +++    G+  VL ++P+ + ES+  F
Sbjct:   34 GAIKVSIYGDRNDPKKVPMVTFHDLGLDSESNFQNFFQFVSIAEFADKFCIYNVNAPGQEMDAQPLPENFTYPTMDGIAKTIESVADHFKLNQFIGFGVGVGANVLLRYAAQNQNRVIALVLVNCCSGKSGWVEWGYEKWNTSYLRKVGMTKFTVDYLMWHHFGRNYDRCSP----DIVRQYRVFFQHLPNPNSLAEFIESYIQRTPLPISRDGTTGVQLKVPVLQLVGAGSAH------VEDTVEVNTKLDPAHADWIKISDSCGL--VLDDRPDAVTESMMLF 306

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BLAST of Protein NDRG4 vs. Ensembl Fly
Match: CG2082 (gene:FBgn0027608 transcript:FBtr0078672)

HSP 1 Score: 188.348 bits (477), Expect = 4.335e-56
Identity = 90/287 (31.36%), Postives = 173/287 (60.28%), Query Frame = 2

Query:   59 VTTPKCGVLNIYIQGNRSPNE--VIIFTIHDLGCNHKEYEQFLEHTSMKHLRNRCVWIHLDIPGQGDNDEDL-NLKEFPTMQEIADDIKVIFDELNIQHAVLFGEGAGANILARFAMNNDDKVLGIVLIHCTGTTAGIKEAIRDRLITWKLNTTGMNPVAESYLVVHRFGEHI-NTNSEKEFREMINGFKRNLQASINPRNLNKFILSFMNRSNIAERIYQLKCPALFVTGNLASHNHTVMTLYNTLQKFVKDDPERIKKLELIQVNGVANVLKEKPEKIAESLQYF 907
            ++T KCG L + +QG+ S  E   +  T+HDLGCNH  +++F+    M  ++ R  +IH+D+PG  DN E L +   FP++Q + +D+  + D L++++ +  GEGAGAN+LARF + +  +VLG++LI+ TG+ A + ++ +++ I+WK +    +  AES+L+ H+FG  I   N +KE  +++  +++ L  S+N +N+  ++ +FMNR ++   +   K   + +TG L+ +   V  L+  ++K         +++ ++++    +VL + P K+A+S+  F
Sbjct:   24 ISTEKCGDLTVIVQGDLSQQEKRAVFITVHDLGCNHNSFQEFVSSPCMTEIKERSCFIHVDVPGHADNAEALADGFPFPSLQSLGEDLVTVLDYLHVKYVIGLGEGAGANVLARFGLAHPSRVLGLILINATGSAASVVQSFKNKFISWKSDEVAQS--AESFLMYHKFGHQIVGENPDKE--KIVAEYQKRLHRSLNSKNIGLYVKAFMNRKDLT--LKGCKVDVILITGMLSPYASMVEKLHRDVEK---------ERVTILKIERAGDVLADAPGKVAQSILLF 295

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BLAST of Protein NDRG4 vs. Ensembl Fly
Match: CG2082 (gene:FBgn0027608 transcript:FBtr0300909)

HSP 1 Score: 188.348 bits (477), Expect = 4.335e-56
Identity = 90/287 (31.36%), Postives = 173/287 (60.28%), Query Frame = 2

Query:   59 VTTPKCGVLNIYIQGNRSPNE--VIIFTIHDLGCNHKEYEQFLEHTSMKHLRNRCVWIHLDIPGQGDNDEDL-NLKEFPTMQEIADDIKVIFDELNIQHAVLFGEGAGANILARFAMNNDDKVLGIVLIHCTGTTAGIKEAIRDRLITWKLNTTGMNPVAESYLVVHRFGEHI-NTNSEKEFREMINGFKRNLQASINPRNLNKFILSFMNRSNIAERIYQLKCPALFVTGNLASHNHTVMTLYNTLQKFVKDDPERIKKLELIQVNGVANVLKEKPEKIAESLQYF 907
            ++T KCG L + +QG+ S  E   +  T+HDLGCNH  +++F+    M  ++ R  +IH+D+PG  DN E L +   FP++Q + +D+  + D L++++ +  GEGAGAN+LARF + +  +VLG++LI+ TG+ A + ++ +++ I+WK +    +  AES+L+ H+FG  I   N +KE  +++  +++ L  S+N +N+  ++ +FMNR ++   +   K   + +TG L+ +   V  L+  ++K         +++ ++++    +VL + P K+A+S+  F
Sbjct:   24 ISTEKCGDLTVIVQGDLSQQEKRAVFITVHDLGCNHNSFQEFVSSPCMTEIKERSCFIHVDVPGHADNAEALADGFPFPSLQSLGEDLVTVLDYLHVKYVIGLGEGAGANVLARFGLAHPSRVLGLILINATGSAASVVQSFKNKFISWKSDEVAQS--AESFLMYHKFGHQIVGENPDKE--KIVAEYQKRLHRSLNSKNIGLYVKAFMNRKDLT--LKGCKVDVILITGMLSPYASMVEKLHRDVEK---------ERVTILKIERAGDVLADAPGKVAQSILLF 295

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BLAST of Protein NDRG4 vs. Ensembl Fly
Match: CG2082 (gene:FBgn0027608 transcript:FBtr0078675)

HSP 1 Score: 187.963 bits (476), Expect = 6.749e-56
Identity = 90/287 (31.36%), Postives = 173/287 (60.28%), Query Frame = 2

Query:   59 VTTPKCGVLNIYIQGNRSPNE--VIIFTIHDLGCNHKEYEQFLEHTSMKHLRNRCVWIHLDIPGQGDNDEDL-NLKEFPTMQEIADDIKVIFDELNIQHAVLFGEGAGANILARFAMNNDDKVLGIVLIHCTGTTAGIKEAIRDRLITWKLNTTGMNPVAESYLVVHRFGEHI-NTNSEKEFREMINGFKRNLQASINPRNLNKFILSFMNRSNIAERIYQLKCPALFVTGNLASHNHTVMTLYNTLQKFVKDDPERIKKLELIQVNGVANVLKEKPEKIAESLQYF 907
            ++T KCG L + +QG+ S  E   +  T+HDLGCNH  +++F+    M  ++ R  +IH+D+PG  DN E L +   FP++Q + +D+  + D L++++ +  GEGAGAN+LARF + +  +VLG++LI+ TG+ A + ++ +++ I+WK +    +  AES+L+ H+FG  I   N +KE  +++  +++ L  S+N +N+  ++ +FMNR ++   +   K   + +TG L+ +   V  L+  ++K         +++ ++++    +VL + P K+A+S+  F
Sbjct:   28 ISTEKCGDLTVIVQGDLSQQEKRAVFITVHDLGCNHNSFQEFVSSPCMTEIKERSCFIHVDVPGHADNAEALADGFPFPSLQSLGEDLVTVLDYLHVKYVIGLGEGAGANVLARFGLAHPSRVLGLILINATGSAASVVQSFKNKFISWKSDEVAQS--AESFLMYHKFGHQIVGENPDKE--KIVAEYQKRLHRSLNSKNIGLYVKAFMNRKDLT--LKGCKVDVILITGMLSPYASMVEKLHRDVEK---------ERVTILKIERAGDVLADAPGKVAQSILLF 299

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BLAST of Protein NDRG4 vs. Ensembl Fly
Match: CG2082 (gene:FBgn0027608 transcript:FBtr0300911)

HSP 1 Score: 186.422 bits (472), Expect = 2.042e-55
Identity = 89/289 (30.80%), Postives = 174/289 (60.21%), Query Frame = 2

Query:   59 VTTPKCGVLNIYIQGNRSPNE--VIIFTIHDLGCNHKEYEQFLEHTSMKHLRNRCVWIHLDIPGQGDNDEDL-NLKEFPTMQEIADDIKVIFDELNIQHAVLFGEGAGANILARFAMNNDDKVLGIVLIHCTGTTAGIKEAIRDRLITWKLNTTGMNPVAESYLVVHRFGEH---INTNSEKEFREMINGFKRNLQASINPRNLNKFILSFMNRSNIAERIYQLKCPALFVTGNLASHNHTVMTLYNTLQKFVKDDPERIKKLELIQVNGVANVLKEKPEKIAESLQYF 907
            ++T KCG L + +QG+ S  E   +  T+HDLGCNH  +++F+    M  ++ R  +IH+D+PG  DN E L +   FP++Q + +D+  + D L++++ +  GEGAGAN+LARF + +  +VLG++LI+ TG+ A + ++ +++ I+WK +    +  AES+L+ H+FG +   +  N +KE  +++  +++ L  S+N +N+  ++ +FMNR ++   +   K   + +TG L+ +   V  L+  ++K         +++ ++++    +VL + P K+A+S+  F
Sbjct:   24 ISTEKCGDLTVIVQGDLSQQEKRAVFITVHDLGCNHNSFQEFVSSPCMTEIKERSCFIHVDVPGHADNAEALADGFPFPSLQSLGEDLVTVLDYLHVKYVIGLGEGAGANVLARFGLAHPSRVLGLILINATGSAASVVQSFKNKFISWKSDEVAQS--AESFLMYHKFGHNWQIVGENPDKE--KIVAEYQKRLHRSLNSKNIGLYVKAFMNRKDLT--LKGCKVDVILITGMLSPYASMVEKLHRDVEK---------ERVTILKIERAGDVLADAPGKVAQSILLF 297

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BLAST of Protein NDRG4 vs. Ensembl Fly
Match: CG2082 (gene:FBgn0027608 transcript:FBtr0300907)

HSP 1 Score: 186.422 bits (472), Expect = 2.042e-55
Identity = 89/289 (30.80%), Postives = 174/289 (60.21%), Query Frame = 2

Query:   59 VTTPKCGVLNIYIQGNRSPNE--VIIFTIHDLGCNHKEYEQFLEHTSMKHLRNRCVWIHLDIPGQGDNDEDL-NLKEFPTMQEIADDIKVIFDELNIQHAVLFGEGAGANILARFAMNNDDKVLGIVLIHCTGTTAGIKEAIRDRLITWKLNTTGMNPVAESYLVVHRFGEH---INTNSEKEFREMINGFKRNLQASINPRNLNKFILSFMNRSNIAERIYQLKCPALFVTGNLASHNHTVMTLYNTLQKFVKDDPERIKKLELIQVNGVANVLKEKPEKIAESLQYF 907
            ++T KCG L + +QG+ S  E   +  T+HDLGCNH  +++F+    M  ++ R  +IH+D+PG  DN E L +   FP++Q + +D+  + D L++++ +  GEGAGAN+LARF + +  +VLG++LI+ TG+ A + ++ +++ I+WK +    +  AES+L+ H+FG +   +  N +KE  +++  +++ L  S+N +N+  ++ +FMNR ++   +   K   + +TG L+ +   V  L+  ++K         +++ ++++    +VL + P K+A+S+  F
Sbjct:   24 ISTEKCGDLTVIVQGDLSQQEKRAVFITVHDLGCNHNSFQEFVSSPCMTEIKERSCFIHVDVPGHADNAEALADGFPFPSLQSLGEDLVTVLDYLHVKYVIGLGEGAGANVLARFGLAHPSRVLGLILINATGSAASVVQSFKNKFISWKSDEVAQS--AESFLMYHKFGHNWQIVGENPDKE--KIVAEYQKRLHRSLNSKNIGLYVKAFMNRKDLT--LKGCKVDVILITGMLSPYASMVEKLHRDVEK---------ERVTILKIERAGDVLADAPGKVAQSILLF 297

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BLAST of Protein NDRG4 vs. Ensembl Zebrafish
Match: ndrg3b (ndrg family member 3b [Source:ZFIN;Acc:ZDB-GENE-030131-5606])

HSP 1 Score: 114.39 bits (285), Expect = 3.254e-28
Identity = 82/295 (27.80%), Postives = 137/295 (46.44%), Query Frame = 2

Query:   59 VTTPKCGVLNIYIQGNRSPNEVIIFTIHDLGCNHKE-YEQFLEHTSMKHLRNRCVWIHLDIPGQGDNDEDLNLK-EFPTMQEIADDIKVIFDELNIQHAVLFGEGAGANILARFAMNNDDKVLGIVLIHCTGTTAGIKEAIRDRLITWKLNTTGMNPVAESYLVVHRFGEHINTNSEKEFREMINGFKRNLQASINPRNLNKFILSFMNRSNIA-ER---------IYQLKCPALFVTGNLASHNHTVMTLYNTLQKFVKDDPERIKKLELIQVNGVANVLKEKPEKIAESLQYF 907
            + TP+ GVL++ ++G    N  +I T HD+G NHK  +        M+ +      +H+D PGQ ++         +PTM E+A+ +  +   L I   +  G GAGA IL RFA+N    V G+VLI+      G  +    +L  W  N           L+      H +T+   E +E+I  ++ ++   IN  NL  F  S+ +R ++  ER         +  LKCPAL + G+ +     V+   + L      +P +   L++    G+  V+  +P K+AE+ +YF
Sbjct:   35 IETPR-GVLHVTLRGTPKGNRPVILTYHDIGLNHKSCFNTLFNFEDMQEITQHFAVVHVDAPGQQESAPPFPTGFLYPTMDELAEMLPSVLTHLKINSVIGIGVGAGAYILTRFALNEPALVEGLVLINVDPCAKGWIDWAASKLSGWTSN-----------LIDIVMAHHFSTDELTENQEIIQTYRLHIAQDINQDNLALFCQSYNSRRDLEIERPVLGMNENAVKTLKCPALLIVGDTSPAVEAVVECNSRL------NPTKTTLLKMADCGGLPQVV--QPGKLAEAFKYF 309

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Query:   59 VTTPKCGVLNIYIQGNRSPNEVIIFTIHDLGCNHKE-YEQFLEHTSMKHLRNRCVWIHLDIPGQGDNDEDLNLK-EFPTMQEIADDIKVIFDELNIQHAVLFGEGAGANILARFAMNNDDKVLGIVLIHCTGTTAGIKEAIRDRLITWKLNTTGMNPVAESYLVVHRFGEHINTNSEKEFREMINGFKRNLQASINPRNLNKFILSFMNRSNIA-ER---------IYQLKCPALFVTGNLASHNHTVMTLYNTLQKFVKDDPERIKKLELIQVNGVANVLKEKPEKIAESLQYF 907
            + TP+ GVL++ ++G    N  +I T HD+G NHK  +        M+ +      +H+D PGQ ++         +PTM E+A+ +  +   L I   +  G GAGA IL RFA+N    V G+VLI+      G  +    +L  W  N           L+      H +T+   E +E+I  ++ ++   IN  NL  F  S+ +R ++  ER         +  LKCPAL + G+ +     V+   + L      +P +   L++    G+  V+  +P K+AE+ +YF
Sbjct:   35 IETPR-GVLHVTLRGTPKGNRPVILTYHDIGLNHKSCFNTLFNFEDMQEITQHFAVVHVDAPGQQESAPPFPTGFLYPTMDELAEMLPSVLTHLKINSVIGIGVGAGAYILTRFALNEPALVEGLVLINVDPCAKGWIDWAASKLSGWTSN-----------LIDIVMAHHFSTDELTENQEIIQTYRLHIAQDINQDNLALFCQSYNSRRDLEIERPVLGMNENAVKTLKCPALLIVGDTSPAVEAVVECNSRL------NPTKTTLLKMADCGGLPQVV--QPGKLAEAFKYF 309

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BLAST of Protein NDRG4 vs. Ensembl Zebrafish
Match: ndrg1b (N-myc downstream regulated 1b [Source:ZFIN;Acc:ZDB-GENE-040426-1648])

HSP 1 Score: 112.464 bits (280), Expect = 1.243e-27
Identity = 77/289 (26.64%), Postives = 139/289 (48.10%), Query Frame = 2

Query:   77 GVLNIYIQGNRSPNEVIIFTIHDLGCNHKE-YEQFLEHTSMKHLRNRCVWIHLDIPGQGDNDEDLNLK-EFPTMQEIADDIKVIFDELNIQHAVLFGEGAGANILARFAMNNDDKVLGIVLIHCTGTTAGIKEAIRDRLITWKLNTTGMNPVAESYLVVHRFG-EHINTNSEKEFREMINGFKRNLQASINPRNLNKFILSFMNRSNIA-ERIYQ--------LKCPALFVTGNLASHNHTVMTLYNTLQKFVKDDPERIKKLELIQVNGVANVLKEKPEKIAESLQYF 907
            G ++  ++G    N   I T HD+G NHK  +E    H  M  +       H+D PGQ +    L+    +P+M ++++ + ++ +   ++  +  G GAGANILARFA+ + D V G+VLI+ +    G  +    ++ +W              ++ H FG E I+ N      E+I  F++ +  +IN  NL +F+ S+ +R ++  ER  Q        L+CPAL + G+ +     V+   + +      +P     L++    G+  V  ++P K+ E+ +YF
Sbjct:   25 GRVHCTMKGVPKGNRPTILTFHDIGLNHKSCFESMFHHKDMHEILQHFAVCHVDAPGQQEGASTLSTDYTYPSMDQLSESLPMVLNHFGLKSVIGMGVGAGANILARFALKHPDMVEGLVLINMSTQAEGFMDWAAQKITSW-------THALPDTVISHLFGKEEIHNN-----HELIATFRQLITNNINQSNLQQFVKSYKSRKDLEIERPVQGGNVNTKTLQCPALLIVGDNSPAVDAVVDSNSRM------NPTTTTFLKMADCGGLPQV--DQPGKLIEAFKYF 293

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BLAST of Protein NDRG4 vs. Ensembl Zebrafish
Match: ndrg3b (ndrg family member 3b [Source:ZFIN;Acc:ZDB-GENE-030131-5606])

HSP 1 Score: 112.464 bits (280), Expect = 1.382e-27
Identity = 78/286 (27.27%), Postives = 134/286 (46.85%), Query Frame = 2

Query:   59 VTTPKCGVLNIYIQGNRSPNEVIIFTIHDLGCNHKE-YEQFLEHTSMKHLRNRCVWIHLDIPGQGDNDEDLNLK-EFPTMQEIADDIKVIFDELNIQHAVLFGEGAGANILARFAMNNDDKVLGIVLIHCTGTTAGIKEAIRDRLITWKLNTTGMNPVAESYLVVHRFGEHINTNSEKEFREMINGFKRNLQASINPRNLNKFILSFMNRSNIAERIYQ-LKCPALFVTGNLASHNHTVMTLYNTLQKFVKDDPERIKKLELIQVNGVANVLKEKPEKIAESLQYF 907
            + TP+ GVL++ ++G    N  +I T HD+G NHK  +        M+ +      +H+D PGQ ++         +PTM E+A+ +  +   L I   +  G GAGA IL RFA+N    V G+VLI+      G  +    +L  W  N           L+      H +T+   E +E+I  ++ ++   IN  NL++  L    R+ +    +  L+CPAL + G+ +     V+   + L      +P +   L++    G+  V+  +P K+AE+ +YF
Sbjct:   35 IETPR-GVLHVTLRGTPKGNRPVILTYHDIGLNHKSCFNTLFNFEDMQEITQHFAVVHVDAPGQQESAPPFPTGFLYPTMDELAEMLPSVLTHLKINSVIGIGVGAGAYILTRFALNEPALVEGLVLINVDPCAKGWIDWAASKLSGWTSN-----------LIDIVMAHHFSTDELTENQEIIQTYRLHIAQDINQDNLDQNTLIIGKRAELNWIFFSLLQCPALLIVGDTSPAVEAVVECNSRL------NPTKTTLLKMADCGGLPQVV--QPGKLAEAFKYF 300

[Close]

BLAST of Protein NDRG4 vs. Ensembl Zebrafish
Match: ndrg3a (ndrg family member 3a [Source:ZFIN;Acc:ZDB-GENE-980526-124])

HSP 1 Score: 108.612 bits (270), Expect = 3.912e-26
Identity = 80/295 (27.12%), Postives = 133/295 (45.08%), Query Frame = 2

Query:   59 VTTPKCGVLNIYIQGNRSPNEVIIFTIHDLGCNHKE-YEQFLEHTSMKHLRNRCVWIHLDIPGQGDNDEDLNLKE-FPTMQEIADDIKVIFDELNIQHAVLFGEGAGANILARFAMNNDDKVLGIVLIHCTGTTAGIKEAIRDRLITWKLNTTGMNPVAESYLVVHRFGEHINTNSEKEFREMINGFKRNLQASINPRNLNKFILSFMNRSNIA-ER---------IYQLKCPALFVTGNLASHNHTVMTLYNTLQKFVKDDPERIKKLELIQVNGVANVLKEKPEKIAESLQYF 907
            + TP  GVL++ ++G+   N  +I T HD+G NHK  +        M  +      +H+D PGQ +          +PTM E+A+ +  +  +L +   +  G GAGA IL RFA+ +   V G+VLI+      G  +    +L  W  N           LV      H +T    + +E+I  ++ ++   IN  NL  F  S+  R ++  ER         +  L CPAL V G+ +     V+   + L      +P +   L++    G+  V+  +P K+AE+ +YF
Sbjct:   21 IETPH-GVLHVTMRGSPKGNRPVILTYHDIGLNHKSCFNTLFNFEDMMEITQHFAVVHVDAPGQQEGGPPFPTGYLYPTMDELAEMLPSVLTQLKVNSVIGIGVGAGAYILTRFALIHPSLVEGLVLINVDPCAEGWIDWAASKLTGWTSN-----------LVDIVMAHHFSTEELTDNQELIQTYRLHIAQDINQDNLALFCGSYNARQDLGIERPIAGLNENIVKTLTCPALLVVGDTSPAVEAVVECNSRL------NPTKTTLLKMADCGGLPQVV--QPGKLAEAFKYF 295

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BLAST of Protein NDRG4 vs. Ensembl Xenopus
Match: kif1a (kinesin family member 1A [Source:Xenbase;Acc:XB-GENE-960470])

HSP 1 Score: 108.227 bits (269), Expect = 7.134e-26
Identity = 77/289 (26.64%), Postives = 135/289 (46.71%), Query Frame = 2

Query:   77 GVLNIYIQGNRSPNEVIIFTIHDLGCNHKE-YEQFLEHTSMKHLRNRCVWIHLDIPGQGDNDEDLNLK-EFPTMQEIADDIKVIFDELNIQHAVLFGEGAGANILARFAMNNDDKVLGIVLIHCTGTTAGIKEAIRDRLITWKLNTTGMNPVAESYLVVHRFG-EHINTNSEKEFREMINGFKRNLQASINPRNLNKFILSFMNRSN--IAERIY-------QLKCPALFVTGNLASHNHTVMTLYNTLQKFVKDDPERIKKLELIQVNGVANVLKEKPEKIAESLQYF 907
            GV+++ + GN   N  ++ T HD+G NHK  +  F     M  +       H+D PGQ +         ++PTM E+A+ +  +   LN++  +  G GAGA +L+RFA+NN   V G+VLI+      G  +    +L  W  N   +       ++   FG E + +N      +++  ++ ++   IN  NL  F+ S+ +R +  I   I+        +KCP L V G+ +     V+   + L      DP R   L++    G+   +  +P K+ E+++YF
Sbjct:   40 GVVHVTMSGNARGNRPVLLTFHDIGLNHKSCFNSFFNFDDMHEITQHFAVCHIDAPGQQEGAPSFPTGYQYPTMDELAEMLCAVLTHLNLRSIIGIGVGAGAYVLSRFALNNPLLVEGLVLINIDPCAKGWIDWAASKLSFWTSNIVEI-------VLGQLFGDEELQSN-----LDLVQTYRLHIAQDINQDNLQLFVTSYNSRKDLEIERPIFGSSTPTNTIKCPVLLVVGDSSPAVDAVVECNSRL------DPTRTTLLKMADCGGLPQAV--QPGKLTEAIKYF 308

[Close]

BLAST of Protein NDRG4 vs. Ensembl Xenopus
Match: kif1a (kinesin family member 1A [Source:Xenbase;Acc:XB-GENE-960470])

HSP 1 Score: 108.227 bits (269), Expect = 8.544e-26
Identity = 77/289 (26.64%), Postives = 135/289 (46.71%), Query Frame = 2

Query:   77 GVLNIYIQGNRSPNEVIIFTIHDLGCNHKE-YEQFLEHTSMKHLRNRCVWIHLDIPGQGDNDEDLNLK-EFPTMQEIADDIKVIFDELNIQHAVLFGEGAGANILARFAMNNDDKVLGIVLIHCTGTTAGIKEAIRDRLITWKLNTTGMNPVAESYLVVHRFG-EHINTNSEKEFREMINGFKRNLQASINPRNLNKFILSFMNRSN--IAERIY-------QLKCPALFVTGNLASHNHTVMTLYNTLQKFVKDDPERIKKLELIQVNGVANVLKEKPEKIAESLQYF 907
            GV+++ + GN   N  ++ T HD+G NHK  +  F     M  +       H+D PGQ +         ++PTM E+A+ +  +   LN++  +  G GAGA +L+RFA+NN   V G+VLI+      G  +    +L  W  N   +       ++   FG E + +N      +++  ++ ++   IN  NL  F+ S+ +R +  I   I+        +KCP L V G+ +     V+   + L      DP R   L++    G+   +  +P K+ E+++YF
Sbjct:   40 GVVHVTMSGNARGNRPVLLTFHDIGLNHKSCFNSFFNFDDMHEITQHFAVCHIDAPGQQEGAPSFPTGYQYPTMDELAEMLCAVLTHLNLRSIIGIGVGAGAYVLSRFALNNPLLVEGLVLINIDPCAKGWIDWAASKLSFWTSNIVEI-------VLGQLFGDEELQSN-----LDLVQTYRLHIAQDINQDNLQLFVTSYNSRKDLEIERPIFGSSTPTNTIKCPVLLVVGDSSPAVDAVVECNSRL------DPTRTTLLKMADCGGLPQAV--QPGKLTEAIKYF 308

[Close]

BLAST of Protein NDRG4 vs. Ensembl Xenopus
Match: slc15a5 (solute carrier family 15, member 5 [Source:Xenbase;Acc:XB-GENE-6049173])

HSP 1 Score: 102.064 bits (253), Expect = 1.485e-23
Identity = 74/287 (25.78%), Postives = 134/287 (46.69%), Query Frame = 2

Query:   77 GVLNIYIQGNRSPNEVIIFTIHDLGCNHKE-YEQFLEHTSMKHLRNRCVWIHLDIPGQGDNDEDLNLKE-FPTMQEIADDIKVIFDELNIQHAVLFGEGAGANILARFAMNNDDKVLGIVLIHCTGTTAGIKEAIRDRLITWKLNTTGMNPVAESYLVVHRFG-EHINTNSEKEFREMINGFKRNLQASINPRNLNKFILSFMNRSNIA-ERIY------QLKCPALFVTGNLASHNHTVMTLYNTLQKFVKDDPERIKKLELIQVNGVANVLKEKPEKIAESLQYF 907
            G++++ + G    N  +I T HD+G NHK  +        M  +       H+D PGQ +          +P+M ++A+ +  +  +L ++  +  G GAGA IL RFA+N+   V G+VLI+      G  +    ++  W      M       ++ H F  + +++N      E++  +++++   IN  NL  F+ S+ +R ++  ER +       LKCPAL V G+ +     V+   + L      DP +   L++    G   V+  +P K+AE+ +YF
Sbjct:   24 GIVHVTMCGTPKLNRPVILTYHDIGLNHKTCFNSLFNFEDMHEITQHFSVCHVDAPGQQEGAASFPAGYMYPSMDQLAEMLPGVIQQLGLKSVLGLGIGAGAYILTRFALNHPSMVEGLVLININPCAEGWMDWAATKISGWTHALPDM-------VISHLFSKDEVHSN-----HELVETYRQHIVQDINQNNLQLFVKSYNSRRDLEIERPFPGSNTVTLKCPALLVVGDSSPAVDAVVDCNSKL------DPTKTTLLKMSDCGGFPQVV--QPAKLAEAFKYF 290

[Close]

BLAST of Protein NDRG4 vs. Ensembl Xenopus
Match: slc15a5 (solute carrier family 15, member 5 [Source:Xenbase;Acc:XB-GENE-6049173])

HSP 1 Score: 102.064 bits (253), Expect = 1.546e-23
Identity = 74/287 (25.78%), Postives = 134/287 (46.69%), Query Frame = 2

Query:   77 GVLNIYIQGNRSPNEVIIFTIHDLGCNHKE-YEQFLEHTSMKHLRNRCVWIHLDIPGQGDNDEDLNLKE-FPTMQEIADDIKVIFDELNIQHAVLFGEGAGANILARFAMNNDDKVLGIVLIHCTGTTAGIKEAIRDRLITWKLNTTGMNPVAESYLVVHRFG-EHINTNSEKEFREMINGFKRNLQASINPRNLNKFILSFMNRSNIA-ERIY------QLKCPALFVTGNLASHNHTVMTLYNTLQKFVKDDPERIKKLELIQVNGVANVLKEKPEKIAESLQYF 907
            G++++ + G    N  +I T HD+G NHK  +        M  +       H+D PGQ +          +P+M ++A+ +  +  +L ++  +  G GAGA IL RFA+N+   V G+VLI+      G  +    ++  W      M       ++ H F  + +++N      E++  +++++   IN  NL  F+ S+ +R ++  ER +       LKCPAL V G+ +     V+   + L      DP +   L++    G   V+  +P K+AE+ +YF
Sbjct:   46 GIVHVTMCGTPKLNRPVILTYHDIGLNHKTCFNSLFNFEDMHEITQHFSVCHVDAPGQQEGAASFPAGYMYPSMDQLAEMLPGVIQQLGLKSVLGLGIGAGAYILTRFALNHPSMVEGLVLININPCAEGWMDWAATKISGWTHALPDM-------VISHLFSKDEVHSN-----HELVETYRQHIVQDINQNNLQLFVKSYNSRRDLEIERPFPGSNTVTLKCPALLVVGDSSPAVDAVVDCNSKL------DPTKTTLLKMSDCGGFPQVV--QPAKLAEAFKYF 312

[Close]

BLAST of Protein NDRG4 vs. Ensembl Xenopus
Match: slc15a5 (solute carrier family 15, member 5 [Source:Xenbase;Acc:XB-GENE-6049173])

HSP 1 Score: 102.064 bits (253), Expect = 1.577e-23
Identity = 74/287 (25.78%), Postives = 134/287 (46.69%), Query Frame = 2

Query:   77 GVLNIYIQGNRSPNEVIIFTIHDLGCNHKE-YEQFLEHTSMKHLRNRCVWIHLDIPGQGDNDEDLNLKE-FPTMQEIADDIKVIFDELNIQHAVLFGEGAGANILARFAMNNDDKVLGIVLIHCTGTTAGIKEAIRDRLITWKLNTTGMNPVAESYLVVHRFG-EHINTNSEKEFREMINGFKRNLQASINPRNLNKFILSFMNRSNIA-ERIY------QLKCPALFVTGNLASHNHTVMTLYNTLQKFVKDDPERIKKLELIQVNGVANVLKEKPEKIAESLQYF 907
            G++++ + G    N  +I T HD+G NHK  +        M  +       H+D PGQ +          +P+M ++A+ +  +  +L ++  +  G GAGA IL RFA+N+   V G+VLI+      G  +    ++  W      M       ++ H F  + +++N      E++  +++++   IN  NL  F+ S+ +R ++  ER +       LKCPAL V G+ +     V+   + L      DP +   L++    G   V+  +P K+AE+ +YF
Sbjct:   30 GIVHVTMCGTPKLNRPVILTYHDIGLNHKTCFNSLFNFEDMHEITQHFSVCHVDAPGQQEGAASFPAGYMYPSMDQLAEMLPGVIQQLGLKSVLGLGIGAGAYILTRFALNHPSMVEGLVLININPCAEGWMDWAATKISGWTHALPDM-------VISHLFSKDEVHSN-----HELVETYRQHIVQDINQNNLQLFVKSYNSRRDLEIERPFPGSNTVTLKCPALLVVGDSSPAVDAVVDCNSKL------DPTKTTLLKMSDCGGFPQVV--QPAKLAEAFKYF 296

[Close]

BLAST of Protein NDRG4 vs. Ensembl Mouse
Match: Ndrg1 (N-myc downstream regulated gene 1 [Source:MGI Symbol;Acc:MGI:1341799])

HSP 1 Score: 114.005 bits (284), Expect = 6.135e-28
Identity = 76/287 (26.48%), Postives = 135/287 (47.04%), Query Frame = 2

Query:   77 GVLNIYIQGNRSPNEVIIFTIHDLGCNHKE-YEQFLEHTSMKHLRNRCVWIHLDIPGQGDNDEDLNLKE-FPTMQEIADDIKVIFDELNIQHAVLFGEGAGANILARFAMNNDDKVLGIVLIHCTGTTAGIKEAIRDRLITWKLNTTGMNPVAESYLVVHRFG-EHINTNSEKEFREMINGFKRNLQASINPRNLNKFILSFMNRSNI-------AERIYQLKCPALFVTGNLASHNHTVMTLYNTLQKFVKDDPERIKKLELIQVNGVANVLKEKPEKIAESLQYF 907
            G L++ + G    N  +I T HD+G NHK  Y        M+ +       H+D PGQ D      +   +P+M ++A+ +  +  +  ++  +  G GAGA IL RFA+NN + V G+VL++      G  +    ++  W      M       +V H FG E I+ N      E+++ +++++   +NP NL+ FI ++ +R ++             L+CPAL V G+ +     V+   + L      DP +   L++    G+  +   +P K+AE+ +YF
Sbjct:   42 GSLHVTLCGTPKGNRPVILTYHDIGMNHKTCYNPLFNSEDMQEITQHFAVCHVDAPGQQDGAPSFPVGYMYPSMDQLAEMLPGVLHQFGLKSVIGMGTGAGAYILTRFALNNPEMVEGLVLMNVNPCAEGWMDWAASKISGWTQALPDM-------VVSHLFGKEEIHNNV-----EVVHTYRQHILNDMNPSNLHLFISAYNSRRDLEIERPMPGTHTVTLQCPALLVVGDNSPAVDAVVECNSKL------DPTKTTLLKMADCGGLPQI--SQPAKLAEAFKYF 308

[Close]

BLAST of Protein NDRG4 vs. Ensembl Mouse
Match: Ndrg2 (N-myc downstream regulated gene 2 [Source:MGI Symbol;Acc:MGI:1352498])

HSP 1 Score: 107.071 bits (266), Expect = 1.670e-25
Identity = 82/293 (27.99%), Postives = 137/293 (46.76%), Query Frame = 2

Query:   47 EVKQVTTPKCGVLNIYIQGNRSPNEVIIFTIHDLGCNHKE-YEQFLEHTSMKHLRNRCVWIHLDIPGQGDNDEDLNLK-EFPTMQEIADDIKVIFDELNIQHAVLFGEGAGANILARFAMNNDDKVLGIVLIHCTGTTAGIKEAIRDRLITWKLNTTGMNPVAESYLVVHRFG-EHINTNSEKEFREMINGFKRNLQASINPRNLNKFILSFMNRSNI-AERIYQ--LKCPALFVTGNLASHNHTVMTLYNTLQKFVKDDPERIKKLELIQVNGVANVLKEKPEKIAESLQYF 907
            +   V TP  G +   + G   P    IFT HD+G N+K  ++       M+ +    V +H+D PG  +      L  ++P++ ++AD I  I   LN    +  G GAGA IL+R+A+N+ D V G+VLI+      G  +    +L       TG+       ++ H F  E ++ NS     E+I  ++  +Q + N  N+  +  S+ NR ++  ER  +  LKCP + V G+ A H   V+   + L      DP +   L++    G   +   +P K+ E+ +YF
Sbjct:   39 QTHSVETPY-GSVTFTVYGTPKPKRPAIFTYHDVGLNYKSCFQPLFRFGDMQEIIQNFVRVHVDAPGMEEGAPVFPLGYQYPSLDQLADMIPCILQYLNFSTIIGVGVGAGAYILSRYALNHPDTVEGLVLINIDPNAKGWMDWAAHKL-------TGLTSSIPDMILGHLFSQEELSGNS-----ELIQKYRGIIQHAPNLENIELYWNSYNNRRDLNFERGGETTLKCPVMLVVGDQAPHEDAVVECNSKL------DPTQTSFLKMADSGGQPQL--TQPGKLTEAFKYF 310

[Close]

BLAST of Protein NDRG4 vs. Ensembl Mouse
Match: Ndrg2 (N-myc downstream regulated gene 2 [Source:MGI Symbol;Acc:MGI:1352498])

HSP 1 Score: 106.686 bits (265), Expect = 1.694e-25
Identity = 82/289 (28.37%), Postives = 136/289 (47.06%), Query Frame = 2

Query:   59 VTTPKCGVLNIYIQGNRSPNEVIIFTIHDLGCNHKE-YEQFLEHTSMKHLRNRCVWIHLDIPGQGDNDEDLNLK-EFPTMQEIADDIKVIFDELNIQHAVLFGEGAGANILARFAMNNDDKVLGIVLIHCTGTTAGIKEAIRDRLITWKLNTTGMNPVAESYLVVHRFG-EHINTNSEKEFREMINGFKRNLQASINPRNLNKFILSFMNRSNI-AERIYQ--LKCPALFVTGNLASHNHTVMTLYNTLQKFVKDDPERIKKLELIQVNGVANVLKEKPEKIAESLQYF 907
            V TP  G +   + G   P    IFT HD+G N+K  ++       M+ +    V +H+D PG  +      L  ++P++ ++AD I  I   LN    +  G GAGA IL+R+A+N+ D V G+VLI+      G  +    +L       TG+       ++ H F  E ++ NS     E+I  ++  +Q + N  N+  +  S+ NR ++  ER  +  LKCP + V G+ A H   V+   + L      DP +   L++    G   +   +P K+ E+ +YF
Sbjct:   29 VETPY-GSVTFTVYGTPKPKRPAIFTYHDVGLNYKSCFQPLFRFGDMQEIIQNFVRVHVDAPGMEEGAPVFPLGYQYPSLDQLADMIPCILQYLNFSTIIGVGVGAGAYILSRYALNHPDTVEGLVLINIDPNAKGWMDWAAHKL-------TGLTSSIPDMILGHLFSQEELSGNS-----ELIQKYRGIIQHAPNLENIELYWNSYNNRRDLNFERGGETTLKCPVMLVVGDQAPHEDAVVECNSKL------DPTQTSFLKMADSGGQPQL--TQPGKLTEAFKYF 296

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BLAST of Protein NDRG4 vs. Ensembl Mouse
Match: Ndrg3 (N-myc downstream regulated gene 3 [Source:MGI Symbol;Acc:MGI:1352499])

HSP 1 Score: 102.449 bits (254), Expect = 8.064e-24
Identity = 78/296 (26.35%), Postives = 137/296 (46.28%), Query Frame = 2

Query:   59 VTTPKCGVLNIYIQGNRSPNEVIIFTIHDLGCNHKE-YEQFLEHTSMKHLRNRCVWIHLDIPGQGDNDEDLNLK-EFPTMQEIADDIKVIFDELNIQHAVLFGEGAGANILARFAMNNDDKVLGIVLIHCTGTTAGIKEAIRDRLITWKLNTTGMNPVAESYLVVHRFG-EHINTNSEKEFREMINGFKRNLQASINPRNLNKFILSFMNRSNIA----------ERIYQLKCPALFVTGNLASHNHTVMTLYNTLQKFVKDDPERIKKLELIQVNGVANVLKEKPEKIAESLQYF 907
            + TP  G++++ I+G    N  +I T HD+G NHK  +  F     M+ +       H+D PGQ +         ++PTM E+A+ +  +   L+++  +  G GAGA IL+RFA+N+ + V G+VLI+      G  +    +L  +  N   +       ++ H FG E +  N      ++I  ++ ++   IN  NL  F+ S+  R ++            R+  LKC  L V G+ +     V+   + L      DP     L++    G+  V+  +P K+ E+ +YF
Sbjct:   35 IETPH-GMVHVTIRGLPKGNRPVILTYHDIGLNHKSCFNTFFNFEDMQEITQHFAVCHVDAPGQQEAAPSFPTGYQYPTMDELAEMLPPVLTHLSMKSIIGIGVGAGAYILSRFALNHPELVEGLVLINIDPCAKGWIDWAASKLSGFTTNIVDI-------ILAHHFGQEELQAN-----LDLIQTYRLHIAQDINQENLQLFLGSYNGRRDLEIERPILGQNDNRLKTLKCSTLLVVGDNSPAVEAVVECNSRL------DPINTTLLKMADCGGLPQVV--QPGKLTEAFKYF 309

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BLAST of Protein NDRG4 vs. Ensembl Mouse
Match: Ndrg3 (N-myc downstream regulated gene 3 [Source:MGI Symbol;Acc:MGI:1352499])

HSP 1 Score: 102.064 bits (253), Expect = 8.765e-24
Identity = 78/296 (26.35%), Postives = 137/296 (46.28%), Query Frame = 2

Query:   59 VTTPKCGVLNIYIQGNRSPNEVIIFTIHDLGCNHKE-YEQFLEHTSMKHLRNRCVWIHLDIPGQGDNDEDLNLK-EFPTMQEIADDIKVIFDELNIQHAVLFGEGAGANILARFAMNNDDKVLGIVLIHCTGTTAGIKEAIRDRLITWKLNTTGMNPVAESYLVVHRFG-EHINTNSEKEFREMINGFKRNLQASINPRNLNKFILSFMNRSNIA----------ERIYQLKCPALFVTGNLASHNHTVMTLYNTLQKFVKDDPERIKKLELIQVNGVANVLKEKPEKIAESLQYF 907
            + TP  G++++ I+G    N  +I T HD+G NHK  +  F     M+ +       H+D PGQ +         ++PTM E+A+ +  +   L+++  +  G GAGA IL+RFA+N+ + V G+VLI+      G  +    +L  +  N   +       ++ H FG E +  N      ++I  ++ ++   IN  NL  F+ S+  R ++            R+  LKC  L V G+ +     V+   + L      DP     L++    G+  V+  +P K+ E+ +YF
Sbjct:   35 IETPH-GMVHVTIRGLPKGNRPVILTYHDIGLNHKSCFNTFFNFEDMQEITQHFAVCHVDAPGQQEAAPSFPTGYQYPTMDELAEMLPPVLTHLSMKSIIGIGVGAGAYILSRFALNHPELVEGLVLINIDPCAKGWIDWAASKLSGFTTNIVDI-------ILAHHFGQEELQAN-----LDLIQTYRLHIAQDINQENLQLFLGSYNGRRDLEIERPILGQNDNRLKTLKCSTLLVVGDNSPAVEAVVECNSRL------DPINTTLLKMADCGGLPQVV--QPGKLTEAFKYF 309

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BLAST of Protein NDRG4 vs. UniProt/SwissProt
Match: sp|O02485|YDJ1_CAEEL (Uncharacterized protein ZK1073.1 OS=Caenorhabditis elegans OX=6239 GN=ZK1073.1 PE=3 SV=1)

HSP 1 Score: 221.09 bits (562), Expect = 2.753e-68
Identity = 118/319 (36.99%), Postives = 195/319 (61.13%), Query Frame = 2

Query:   59 VTTPKCGVLNIYIQGN--RSPNEVIIFTIHDLGCNHKEYEQFLEHTSMKHLRNRCVWIHLDIPGQGDNDEDLNLKEFPTMQEIADDIKVIFDELNIQHAVLFGEGAGANILARFAMNNDDKVLGIVLIHCTGTTAGIKEAIRDRLITWKLNTTGMNPVAESYLVVHRFGEHINTNSEKEFREMINGFKRNLQASINPRNLNKFILSFMNRSNIAERIYQL--KCPALFVTGNLASHNHTVMTLYNTLQKFVKDDPERIKKLELIQVNGVANVLKEKPEKIAESLQYFXXXXXXXXXXRVHSLCNPLSRRLSMEQLDLPR 1003
            V    CGVL++Y+QGN      + II T+HD+G NHK + +F+ H SM  ++ + +++H+ +PGQ DN  D    +FPT+  I DD+  + D+  ++ A+ FGEG GANI+ RFAM + ++++GIVL+HCT TTAGI E  +++++  +L  + M+  A  YL+ H+FG    + S +E+ E        L+A++NP+NL+K++++F  R++++  I        AL VTG+ ASH HTV T + ++ K         KK  L+ V+ VA+V++E P+K+A SL    +G G++ G+ +  +    +   SME+ D PR
Sbjct:   11 VQAQNCGVLHVYVQGNLEERGGKTIILTVHDIGTNHKSFVRFVNHPSMATVKEKAIFLHVCVPGQEDNSADF-FGDFPTLDGIGDDLSAVLDKFEVKSAIAFGEGVGANIICRFAMGHPNRIMGIVLVHCTSTTAGIIEYCKEKVMNMRLENSIMSDGAWDYLLAHKFGG--ESKSRQEYLE-------ELKATLNPKNLSKYLVAFTKRTDLSSTIGTKLETVDALLVTGSKASHLHTVYTTHKSMNK---------KKTTLLVVDNVADVMQEAPDKLARSLILLCKGCGVLSGVAIPGMERQRTLSSSMEEADRPR 310

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BLAST of Protein NDRG4 vs. UniProt/SwissProt
Match: sp|Q6JE36|NDRG1_RAT (Protein NDRG1 OS=Rattus norvegicus OX=10116 GN=Ndrg1 PE=1 SV=1)

HSP 1 Score: 115.161 bits (287), Expect = 2.180e-27
Identity = 76/287 (26.48%), Postives = 136/287 (47.39%), Query Frame = 2

Query:   77 GVLNIYIQGNRSPNEVIIFTIHDLGCNHKE-YEQFLEHTSMKHLRNRCVWIHLDIPGQGDNDEDLNLKE-FPTMQEIADDIKVIFDELNIQHAVLFGEGAGANILARFAMNNDDKVLGIVLIHCTGTTAGIKEAIRDRLITWKLNTTGMNPVAESYLVVHRFG-EHINTNSEKEFREMINGFKRNLQASINPRNLNKFILSFMNRSNI-------AERIYQLKCPALFVTGNLASHNHTVMTLYNTLQKFVKDDPERIKKLELIQVNGVANVLKEKPEKIAESLQYF 907
            G L++ + G    N  +I T HD+G NHK  Y        M+ +       H+D PGQ D      +   +P+M ++A+ +  +  +  ++  +  G GAGA IL RFA+NN + V G+VL++      G  +    ++  W      M       +V H FG E I++N      E+++ +++++   +NP NL+ FI ++ +R ++             L+CPAL V G+ +     V+   + L      DP +   L++    G+  +   +P K+AE+ +YF
Sbjct:   42 GSLHVTLCGTPKGNRPVILTYHDIGMNHKTCYNPLFNSEDMQEITQHFAVCHVDAPGQQDGAPSFPVGYMYPSMDQLAEMLPGVLHKFGLKSVIGMGTGAGAYILTRFALNNPEMVEGLVLMNVNPCAEGWMDWAASKISGWTQALPDM-------VVSHLFGKEEIHSNV-----EVVHTYRQHILNDMNPSNLHLFISAYNSRRDLEIERPMPGTHTVTLQCPALLVVGDNSPAVDAVVECNSKL------DPTKTTLLKMADCGGLPQI--SQPAKLAEAFKYF 308

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BLAST of Protein NDRG4 vs. UniProt/SwissProt
Match: sp|Q62433|NDRG1_MOUSE (Protein NDRG1 OS=Mus musculus OX=10090 GN=Ndrg1 PE=1 SV=1)

HSP 1 Score: 114.005 bits (284), Expect = 4.292e-27
Identity = 76/287 (26.48%), Postives = 135/287 (47.04%), Query Frame = 2

Query:   77 GVLNIYIQGNRSPNEVIIFTIHDLGCNHKE-YEQFLEHTSMKHLRNRCVWIHLDIPGQGDNDEDLNLKE-FPTMQEIADDIKVIFDELNIQHAVLFGEGAGANILARFAMNNDDKVLGIVLIHCTGTTAGIKEAIRDRLITWKLNTTGMNPVAESYLVVHRFG-EHINTNSEKEFREMINGFKRNLQASINPRNLNKFILSFMNRSNI-------AERIYQLKCPALFVTGNLASHNHTVMTLYNTLQKFVKDDPERIKKLELIQVNGVANVLKEKPEKIAESLQYF 907
            G L++ + G    N  +I T HD+G NHK  Y        M+ +       H+D PGQ D      +   +P+M ++A+ +  +  +  ++  +  G GAGA IL RFA+NN + V G+VL++      G  +    ++  W      M       +V H FG E I+ N      E+++ +++++   +NP NL+ FI ++ +R ++             L+CPAL V G+ +     V+   + L      DP +   L++    G+  +   +P K+AE+ +YF
Sbjct:   42 GSLHVTLCGTPKGNRPVILTYHDIGMNHKTCYNPLFNSEDMQEITQHFAVCHVDAPGQQDGAPSFPVGYMYPSMDQLAEMLPGVLHQFGLKSVIGMGTGAGAYILTRFALNNPEMVEGLVLMNVNPCAEGWMDWAASKISGWTQALPDM-------VVSHLFGKEEIHNNV-----EVVHTYRQHILNDMNPSNLHLFISAYNSRRDLEIERPMPGTHTVTLQCPALLVVGDNSPAVDAVVECNSKL------DPTKTTLLKMADCGGLPQI--SQPAKLAEAFKYF 308

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BLAST of Protein NDRG4 vs. UniProt/SwissProt
Match: sp|Q92597|NDRG1_HUMAN (Protein NDRG1 OS=Homo sapiens OX=9606 GN=NDRG1 PE=1 SV=1)

HSP 1 Score: 113.235 bits (282), Expect = 8.193e-27
Identity = 75/287 (26.13%), Postives = 135/287 (47.04%), Query Frame = 2

Query:   77 GVLNIYIQGNRSPNEVIIFTIHDLGCNHKE-YEQFLEHTSMKHLRNRCVWIHLDIPGQGDNDEDLNLKE-FPTMQEIADDIKVIFDELNIQHAVLFGEGAGANILARFAMNNDDKVLGIVLIHCTGTTAGIKEAIRDRLITWKLNTTGMNPVAESYLVVHRFG-EHINTNSEKEFREMINGFKRNLQASINPRNLNKFILSFMNRSNI-------AERIYQLKCPALFVTGNLASHNHTVMTLYNTLQKFVKDDPERIKKLELIQVNGVANVLKEKPEKIAESLQYF 907
            G +++ + G    N  +I T HD+G NHK  Y     +  M+ +       H+D PGQ D          +P+M ++A+ +  +  +  ++  +  G GAGA IL RFA+NN + V G+VLI+      G  +    ++  W      M       +V H FG E + +N      E+++ +++++   +NP NL+ FI ++ +R ++             L+CPAL V G+ +     V+   + L      DP +   L++    G+  +   +P K+AE+ +YF
Sbjct:   42 GSVHVTLCGTPKGNRPVILTYHDIGMNHKTCYNPLFNYEDMQEITQHFAVCHVDAPGQQDGAASFPAGYMYPSMDQLAEMLPGVLQQFGLKSIIGMGTGAGAYILTRFALNNPEMVEGLVLINVNPCAEGWMDWAASKISGWTQALPDM-------VVSHLFGKEEMQSNV-----EVVHTYRQHIVNDMNPGNLHLFINAYNSRRDLEIERPMPGTHTVTLQCPALLVVGDSSPAVDAVVECNSKL------DPTKTTLLKMADCGGLPQI--SQPAKLAEAFKYF 308

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BLAST of Protein NDRG4 vs. UniProt/SwissProt
Match: sp|Q4R4Q3|NDRG1_MACFA (Protein NDRG1 OS=Macaca fascicularis OX=9541 GN=Ndrg1 PE=2 SV=1)

HSP 1 Score: 113.235 bits (282), Expect = 8.526e-27
Identity = 75/287 (26.13%), Postives = 136/287 (47.39%), Query Frame = 2

Query:   77 GVLNIYIQGNRSPNEVIIFTIHDLGCNHKE-YEQFLEHTSMKHLRNRCVWIHLDIPGQGDNDEDLNLKE-FPTMQEIADDIKVIFDELNIQHAVLFGEGAGANILARFAMNNDDKVLGIVLIHCTGTTAGIKEAIRDRLITWKLNTTGMNPVAESYLVVHRFG-EHINTNSEKEFREMINGFKRNLQASINPRNLNKFILSFMNRSNI-------AERIYQLKCPALFVTGNLASHNHTVMTLYNTLQKFVKDDPERIKKLELIQVNGVANVLKEKPEKIAESLQYF 907
            G +++ + G    N  +I T HD+G NHK  Y     +  M+ +       H+D PGQ D          +P+M ++A+ +  +  +  ++  +  G GAGA IL RFA+NN + V G+VLI+      G  +    ++  W      M       +V H FG E +++N      E+++ +++++   +NP NL+ FI ++ +R ++             L+CPAL V G+ +     V+   + L      DP +   L++    G+  +   +P K+AE+ +YF
Sbjct:   42 GSVHVTLCGTPKGNRPVILTYHDIGMNHKTCYNPLFNYEDMQEITQHFAVCHVDAPGQQDGAASFPAGYMYPSMDQLAEMLPGVLQQFGLKSIIGMGTGAGAYILTRFALNNPEMVEGLVLINVNPCAEGWMDWAASKISGWTQALPDM-------VVSHLFGKEEMHSNV-----EVVHTYRQHIVNDMNPGNLHLFINAYNSRRDLEIERPMPGTHTVTLQCPALLVVGDSSPAVDAVVECNSKL------DPTKTTLLKMADCGGLPQI--SQPAKLAEAFKYF 308

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BLAST of Protein NDRG4 vs. TrEMBL
Match: C1L4M7 (Uncharacterized protein OS=Schistosoma japonicum OX=6182 PE=2 SV=1)

HSP 1 Score: 348.591 bits (893), Expect = 4.580e-116
Identity = 162/292 (55.48%), Postives = 215/292 (73.63%), Query Frame = 2

Query:   35 MVEIEVKQVTTPKCGVLNIYIQGNRSPNEVIIFTIHDLGCNHKEYEQFLEHTSMKHLRNRCVWIHLDIPGQGDNDEDLNLK-EFPTMQEIADDIKVIFDELNIQHAVLFGEGAGANILARFAMNNDDKVLGIVLIHCTGTTAGIKEAIRDRLITWKLNTTGMNPVAESYLVVHRFGEHINTNSEKEFREMINGFKRNLQASINPRNLNKFILSFMNRSNIAERIYQLKCPALFVTGNLASHNHTVMTLYNTLQKFVKDDPERIKKLELIQVNGVANVLKEKPEKIAESLQYF 907
            M  I+ + V T  CG LN+++QG R+ N V   T+HDLGCNH E   FL H SM+ L NRC WIH+D+PGQGD + DL     FP++Q++A+ +  + + L +QH V+FGEGAGANIL R  M   D VLG VLIHCTGTTAG+ E++RDRLI WKLNT GMNP AESYL++HRFG   +   E E RE++  F+++L+ +INPRNLNK+I+SFM+R+ I E++ Q++CP LF+TG LASHNHTV+ LYN L   V++DP    K+EL+Q++ VANVL E+PEK+A+ LQYF
Sbjct:    1 MSAIQHEVVDTESCGKLNVFMQGPRNTN-VAFLTVHDLGCNHNEMVHFLAHESMEPLANRCTWIHVDVPGQGDGESDLPPDYTFPSVQQLAEGMSEVCNALRLQHIVVFGEGAGANILVRLVMLRYDLVLGAVLIHCTGTTAGLSESLRDRLIGWKLNTVGMNPAAESYLLMHRFGSAADAEDEVELREVLVKFRQSLRTAINPRNLNKYIMSFMSRTKILEQVDQMRCPVLFLTGTLASHNHTVLRLYNALLSAVRNDPILQGKVELVQIDNVANVLSEQPEKVADCLQYF 291

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BLAST of Protein NDRG4 vs. TrEMBL
Match: C7TZF8 (Uncharacterized protein OS=Schistosoma japonicum OX=6182 GN=EWB00_003869 PE=2 SV=1)

HSP 1 Score: 350.903 bits (899), Expect = 4.591e-116
Identity = 177/329 (53.80%), Postives = 234/329 (71.12%), Query Frame = 2

Query:   35 MVEIEVKQVTTPKCGVLNIYIQGNRSPNEVIIFTIHDLGCNHKEYEQFLEHTSMKHLRNRCVWIHLDIPGQGDNDEDLNLK-EFPTMQEIADDIKVIFDELNIQHAVLFGEGAGANILARFAMNNDDKVLGIVLIHCTGTTAGIKEAIRDRLITWKLNTTGMNPVAESYLVVHRFGEHINTNSEKEFREMINGFKRNLQASINPRNLNKFILSFMNRSNIAERIYQLKCPALFVTGNLASHNHTVMTLYNTLQKFVKDDPERIKKLELIQVNGVANVLKEKPEKIAESLQYFXXXXXXX--XXXRVHSLCNPLS--RRLSMEQLDLPRG 1006
            M  I+ + V T  CG LN+++QG R+ N V   T+HDLGCNH E   FL H SM+ L NRC WIH+D+PGQGD + DL     FP++Q++A+ +  + + L +QH V+FGEGAGANIL R  M   D VLG VLIHCTGTTAG+ E++RDRLI WKLNT GMNP AESYL++HRFG   +   E E RE++  F+++L+ +INPRNLNK+I+SFM+R+ I E + Q++CP L +TG LASHNHTV+ LYN L   V++DP    K+EL+Q++ VANVL E+PEK+A+ LQYF+QGLGL      R  S   P++  R LSME+ D P+G
Sbjct:    1 MSAIQHEVVDTESCGKLNVFMQGPRNTN-VAFLTVHDLGCNHNEMVHFLAHESMEPLANRCTWIHVDVPGQGDGESDLPPDYTFPSVQQLAEGMSEVCNALRLQHIVVFGEGAGANILVRLVMLRYDLVLGAVLIHCTGTTAGLSESLRDRLIGWKLNTVGMNPAAESYLLMHRFGSAADAEDEVELREVLVKFRQSLRTAINPRNLNKYIMSFMSRTKILEHVDQIRCPVLLLTGTLASHNHTVLRLYNALLSAVRNDPILQGKVELVQIDNVANVLSEQPEKVADCLQYFIQGLGLAGGLVNRRMSSTIPVARNRSLSMEEYDQPKG 328

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BLAST of Protein NDRG4 vs. TrEMBL
Match: A0A3Q0KUE1 (Family S33 non-peptidase homologue (S33 family) OS=Schistosoma mansoni OX=6183 PE=4 SV=1)

HSP 1 Score: 350.517 bits (898), Expect = 7.417e-116
Identity = 177/329 (53.80%), Postives = 235/329 (71.43%), Query Frame = 2

Query:   35 MVEIEVKQVTTPKCGVLNIYIQGNRSPNEVIIFTIHDLGCNHKEYEQFLEHTSMKHLRNRCVWIHLDIPGQGDNDEDLNLK-EFPTMQEIADDIKVIFDELNIQHAVLFGEGAGANILARFAMNNDDKVLGIVLIHCTGTTAGIKEAIRDRLITWKLNTTGMNPVAESYLVVHRFGEHINTNSEKEFREMINGFKRNLQASINPRNLNKFILSFMNRSNIAERIYQLKCPALFVTGNLASHNHTVMTLYNTLQKFVKDDPERIKKLELIQVNGVANVLKEKPEKIAESLQYFXXXXXXX--XXXRVHSLCNPLS--RRLSMEQLDLPRG 1006
            M  +E + V T  CG +N++IQG R+  +V   T+HDLGCNH E   FL H SM+ L NRC W+H+D+PGQGD + DL     FP++Q++A+ +  + + L +Q+ V+FGEGAGANIL R  M   D VLG VLIHCTGTTAG+ E +RDRLI WKLNT GMNP AESYL++HRFG   ++  E E RE++  F+++L+ +INPRNLNKFI+SFM+R+ I E + Q++CP LF+TG LASHNHTV  LYN +   V++DP    K+ELIQ++ VANVL E+PEK+AESLQ+F+QGLGL      R  S   P++  R LSME+ D P+G
Sbjct:    1 MSGVEHQVVNTESCGKINVFIQGPRN-TKVAFLTVHDLGCNHNEIVNFLAHESMEPLVNRCTWVHVDVPGQGDGESDLPADYTFPSVQQLAEGMSEVCNALRLQYVVVFGEGAGANILVRLVMLRYDIVLGAVLIHCTGTTAGLSENLRDRLIGWKLNTVGMNPAAESYLLMHRFGSAADSEDEVEVREVLIKFRQSLRTAINPRNLNKFIMSFMSRTKILEHVDQIRCPVLFLTGALASHNHTVFRLYNAVLSAVRNDPNLQGKVELIQLDNVANVLSEQPEKVAESLQFFIQGLGLAGGLVSRRMSSTIPVARNRSLSMEEYDQPKG 328

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BLAST of Protein NDRG4 vs. TrEMBL
Match: Q5DF09 (SJCHGC02626 protein OS=Schistosoma japonicum OX=6182 PE=2 SV=1)

HSP 1 Score: 349.362 bits (895), Expect = 9.421e-116
Identity = 176/328 (53.66%), Postives = 233/328 (71.04%), Query Frame = 2

Query:   35 MVEIEVKQVTTPKCGVLNIYIQGNRSPNEVIIFTIHDLGCNHKEYEQFLEHTSMKHLRNRCVWIHLDIPGQGDNDEDLNLK-EFPTMQEIADDIKVIFDELNIQHAVLFGEGAGANILARFAMNNDDKVLGIVLIHCTGTTAGIKEAIRDRLITWKLNTTGMNPVAESYLVVHRFGEHINTNSEKEFREMINGFKRNLQASINPRNLNKFILSFMNRSNIAERIYQLKCPALFVTGNLASHNHTVMTLYNTLQKFVKDDPERIKKLELIQVNGVANVLKEKPEKIAESLQYFXXXXXXX--XXXRVHSLCNPLS--RRLSMEQLDLPR 1003
            M  I+ + V T  CG LN+++QG R+ N V   T+HDLGCNH E   FL H SM+ L NRC WIH+D+PGQGD + DL     FP++Q++A+ +  + + L +QH V+FGEGAGANIL R  M   D VLG VLIHCTGTTAG+ E++RDRLI WKLNT GMNP AESYL++HRFG   +   E E RE++  F+++L+ +INPRNLNK+I+SFM+R+ I E + Q++CP L +TG LASHNHTV+ LYN L   V++DP    K+EL+Q++ VANVL E+PEK+A+ LQYF+QGLGL      R  S   P++  R LSME+ D P+
Sbjct:    1 MSAIQHEVVDTESCGKLNVFMQGPRNTN-VAFLTVHDLGCNHNEMVHFLAHESMEPLANRCTWIHVDVPGQGDGESDLPPDYTFPSVQQLAEGMSEVCNALRLQHIVVFGEGAGANILVRLVMLRYDLVLGAVLIHCTGTTAGLSESLRDRLIGWKLNTVGMNPAAESYLLMHRFGSAADAEDEVELREVLVKFRQSLRTAINPRNLNKYIMSFMSRTKILEHVDQIRCPVLLLTGTLASHNHTVLRLYNALLSAVRNDPILQGKVELVQIDNVANVLSEQPEKVADCLQYFIQGLGLAGGLVNRRMSSTIPVARNRSLSMEEYDQPK 327

[Close]

BLAST of Protein NDRG4 vs. TrEMBL
Match: A0A4Z2D724 (Uncharacterized protein OS=Schistosoma japonicum OX=6182 GN=EWB00_003869 PE=4 SV=1)

HSP 1 Score: 345.51 bits (885), Expect = 8.239e-115
Identity = 161/292 (55.14%), Postives = 213/292 (72.95%), Query Frame = 2

Query:   35 MVEIEVKQVTTPKCGVLNIYIQGNRSPNEVIIFTIHDLGCNHKEYEQFLEHTSMKHLRNRCVWIHLDIPGQGDNDEDLNLK-EFPTMQEIADDIKVIFDELNIQHAVLFGEGAGANILARFAMNNDDKVLGIVLIHCTGTTAGIKEAIRDRLITWKLNTTGMNPVAESYLVVHRFGEHINTNSEKEFREMINGFKRNLQASINPRNLNKFILSFMNRSNIAERIYQLKCPALFVTGNLASHNHTVMTLYNTLQKFVKDDPERIKKLELIQVNGVANVLKEKPEKIAESLQYF 907
            M  I+ + V T  CG LN+++QG R+ N V   T+HDLGCNH E   FL H SM+ L NRC WIH+D+PGQGD + DL     FP++Q++A+ +  + + L +QH V+FGEGAGANIL R  M   D VLG VLIHCTGTTAG+ E++RDRLI WKLNT GMNP AESYL++HRFG   +   E E RE++  F+++L+ +INPRNLNK+I+SFM+R+ I E + Q++CP L +TG LASHNHTV+ LYN L   V++DP    K+EL+Q++ VANVL E+PEK+A+ LQYF
Sbjct:    1 MSAIQHEVVDTESCGKLNVFMQGPRNTN-VAFLTVHDLGCNHNEMVHFLAHESMEPLANRCTWIHVDVPGQGDGESDLPPDYTFPSVQQLAEGMSEVCNALRLQHIVVFGEGAGANILVRLVMLRYDLVLGAVLIHCTGTTAGLSESLRDRLIGWKLNTVGMNPAAESYLLMHRFGSAADAEDEVELREVLVKFRQSLRTAINPRNLNKYIMSFMSRTKILEHVDQIRCPVLLLTGTLASHNHTVLRLYNALLSAVRNDPILQGKVELVQIDNVANVLSEQPEKVADCLQYF 291

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BLAST of Protein NDRG4 vs. Ensembl Cavefish
Match: ndrg3b (ndrg family member 3b [Source:ZFIN;Acc:ZDB-GENE-030131-5606])

HSP 1 Score: 120.168 bits (300), Expect = 1.764e-30
Identity = 84/295 (28.47%), Postives = 137/295 (46.44%), Query Frame = 2

Query:   59 VTTPKCGVLNIYIQGNRSPNEVIIFTIHDLGCNHKE-YEQFLEHTSMKHLRNRCVWIHLDIPGQGDNDEDL-NLKEFPTMQEIADDIKVIFDELNIQHAVLFGEGAGANILARFAMNNDDKVLGIVLIHCTGTTAGIKEAIRDRLITWKLNTTGMNPVAESYLVVHRFGEHINTNSEKEFREMINGFKRNLQASINPRNLNKFILSFMNRSNI----------AERIYQLKCPALFVTGNLASHNHTVMTLYNTLQKFVKDDPERIKKLELIQVNGVANVLKEKPEKIAESLQYF 907
            + TP  GVL++ ++G    N  +I T HD+G NHK  +        M+ +      +H+D PGQ +N     +  ++PTM E+A+ +  +  +L I   +  G GAGA IL R A+N    V G+VLI+      G  +    +L  W  N           LV    G H +T+   E +E+I  ++ ++   IN  NL  F  S+  R ++           E +  LKCPAL V G+ +     V+   + L      +P +   L++    G+  V+  +P K+AE+ +YF
Sbjct:   21 IETPH-GVLHVTLRGTPKGNRPVILTYHDIGLNHKSCFNTLFNFEDMQEITQHFAVVHVDAPGQQENAPPFPSGYQYPTMDELAEMLPSVLTQLKINSVIGIGVGAGAYILTRLALNQSTLVEGLVLINVDPCAKGWMDWAASKLSGWTSN-----------LVDIVMGHHFSTDELTENQEIIQTYRLHIAQDINQDNLALFCNSYNGRRDLEIERPILGINEETVNTLKCPALLVVGDTSPAVEAVVECNSRL------NPTKTTLLKMADCGGLPQVV--QPGKLAEAFKYF 295

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BLAST of Protein NDRG4 vs. Ensembl Cavefish
Match: ndrg3b (ndrg family member 3b [Source:ZFIN;Acc:ZDB-GENE-030131-5606])

HSP 1 Score: 120.168 bits (300), Expect = 4.752e-30
Identity = 84/295 (28.47%), Postives = 137/295 (46.44%), Query Frame = 2

Query:   59 VTTPKCGVLNIYIQGNRSPNEVIIFTIHDLGCNHKE-YEQFLEHTSMKHLRNRCVWIHLDIPGQGDNDEDL-NLKEFPTMQEIADDIKVIFDELNIQHAVLFGEGAGANILARFAMNNDDKVLGIVLIHCTGTTAGIKEAIRDRLITWKLNTTGMNPVAESYLVVHRFGEHINTNSEKEFREMINGFKRNLQASINPRNLNKFILSFMNRSNI----------AERIYQLKCPALFVTGNLASHNHTVMTLYNTLQKFVKDDPERIKKLELIQVNGVANVLKEKPEKIAESLQYF 907
            + TP  GVL++ ++G    N  +I T HD+G NHK  +        M+ +      +H+D PGQ +N     +  ++PTM E+A+ +  +  +L I   +  G GAGA IL R A+N    V G+VLI+      G  +    +L  W  N           LV    G H +T+   E +E+I  ++ ++   IN  NL  F  S+  R ++           E +  LKCPAL V G+ +     V+   + L      +P +   L++    G+  V+  +P K+AE+ +YF
Sbjct:   71 IETPH-GVLHVTLRGTPKGNRPVILTYHDIGLNHKSCFNTLFNFEDMQEITQHFAVVHVDAPGQQENAPPFPSGYQYPTMDELAEMLPSVLTQLKINSVIGIGVGAGAYILTRLALNQSTLVEGLVLINVDPCAKGWMDWAASKLSGWTSN-----------LVDIVMGHHFSTDELTENQEIIQTYRLHIAQDINQDNLALFCNSYNGRRDLEIERPILGINEETVNTLKCPALLVVGDTSPAVEAVVECNSRL------NPTKTTLLKMADCGGLPQVV--QPGKLAEAFKYF 345

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BLAST of Protein NDRG4 vs. Ensembl Cavefish
Match: ndrg3b (ndrg family member 3b [Source:ZFIN;Acc:ZDB-GENE-030131-5606])

HSP 1 Score: 120.168 bits (300), Expect = 5.538e-30
Identity = 84/295 (28.47%), Postives = 137/295 (46.44%), Query Frame = 2

Query:   59 VTTPKCGVLNIYIQGNRSPNEVIIFTIHDLGCNHKE-YEQFLEHTSMKHLRNRCVWIHLDIPGQGDNDEDL-NLKEFPTMQEIADDIKVIFDELNIQHAVLFGEGAGANILARFAMNNDDKVLGIVLIHCTGTTAGIKEAIRDRLITWKLNTTGMNPVAESYLVVHRFGEHINTNSEKEFREMINGFKRNLQASINPRNLNKFILSFMNRSNI----------AERIYQLKCPALFVTGNLASHNHTVMTLYNTLQKFVKDDPERIKKLELIQVNGVANVLKEKPEKIAESLQYF 907
            + TP  GVL++ ++G    N  +I T HD+G NHK  +        M+ +      +H+D PGQ +N     +  ++PTM E+A+ +  +  +L I   +  G GAGA IL R A+N    V G+VLI+      G  +    +L  W  N           LV    G H +T+   E +E+I  ++ ++   IN  NL  F  S+  R ++           E +  LKCPAL V G+ +     V+   + L      +P +   L++    G+  V+  +P K+AE+ +YF
Sbjct:   82 IETPH-GVLHVTLRGTPKGNRPVILTYHDIGLNHKSCFNTLFNFEDMQEITQHFAVVHVDAPGQQENAPPFPSGYQYPTMDELAEMLPSVLTQLKINSVIGIGVGAGAYILTRLALNQSTLVEGLVLINVDPCAKGWMDWAASKLSGWTSN-----------LVDIVMGHHFSTDELTENQEIIQTYRLHIAQDINQDNLALFCNSYNGRRDLEIERPILGINEETVNTLKCPALLVVGDTSPAVEAVVECNSRL------NPTKTTLLKMADCGGLPQVV--QPGKLAEAFKYF 356

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BLAST of Protein NDRG4 vs. Ensembl Cavefish
Match: ndrg3b (ndrg family member 3b [Source:ZFIN;Acc:ZDB-GENE-030131-5606])

HSP 1 Score: 120.168 bits (300), Expect = 6.460e-30
Identity = 84/295 (28.47%), Postives = 137/295 (46.44%), Query Frame = 2

Query:   59 VTTPKCGVLNIYIQGNRSPNEVIIFTIHDLGCNHKE-YEQFLEHTSMKHLRNRCVWIHLDIPGQGDNDEDL-NLKEFPTMQEIADDIKVIFDELNIQHAVLFGEGAGANILARFAMNNDDKVLGIVLIHCTGTTAGIKEAIRDRLITWKLNTTGMNPVAESYLVVHRFGEHINTNSEKEFREMINGFKRNLQASINPRNLNKFILSFMNRSNI----------AERIYQLKCPALFVTGNLASHNHTVMTLYNTLQKFVKDDPERIKKLELIQVNGVANVLKEKPEKIAESLQYF 907
            + TP  GVL++ ++G    N  +I T HD+G NHK  +        M+ +      +H+D PGQ +N     +  ++PTM E+A+ +  +  +L I   +  G GAGA IL R A+N    V G+VLI+      G  +    +L  W  N           LV    G H +T+   E +E+I  ++ ++   IN  NL  F  S+  R ++           E +  LKCPAL V G+ +     V+   + L      +P +   L++    G+  V+  +P K+AE+ +YF
Sbjct:  106 IETPH-GVLHVTLRGTPKGNRPVILTYHDIGLNHKSCFNTLFNFEDMQEITQHFAVVHVDAPGQQENAPPFPSGYQYPTMDELAEMLPSVLTQLKINSVIGIGVGAGAYILTRLALNQSTLVEGLVLINVDPCAKGWMDWAASKLSGWTSN-----------LVDIVMGHHFSTDELTENQEIIQTYRLHIAQDINQDNLALFCNSYNGRRDLEIERPILGINEETVNTLKCPALLVVGDTSPAVEAVVECNSRL------NPTKTTLLKMADCGGLPQVV--QPGKLAEAFKYF 380

[Close]

BLAST of Protein NDRG4 vs. Ensembl Cavefish
Match: ndrg3b (ndrg family member 3b [Source:ZFIN;Acc:ZDB-GENE-030131-5606])

HSP 1 Score: 120.168 bits (300), Expect = 6.465e-30
Identity = 84/295 (28.47%), Postives = 137/295 (46.44%), Query Frame = 2

Query:   59 VTTPKCGVLNIYIQGNRSPNEVIIFTIHDLGCNHKE-YEQFLEHTSMKHLRNRCVWIHLDIPGQGDNDEDL-NLKEFPTMQEIADDIKVIFDELNIQHAVLFGEGAGANILARFAMNNDDKVLGIVLIHCTGTTAGIKEAIRDRLITWKLNTTGMNPVAESYLVVHRFGEHINTNSEKEFREMINGFKRNLQASINPRNLNKFILSFMNRSNI----------AERIYQLKCPALFVTGNLASHNHTVMTLYNTLQKFVKDDPERIKKLELIQVNGVANVLKEKPEKIAESLQYF 907
            + TP  GVL++ ++G    N  +I T HD+G NHK  +        M+ +      +H+D PGQ +N     +  ++PTM E+A+ +  +  +L I   +  G GAGA IL R A+N    V G+VLI+      G  +    +L  W  N           LV    G H +T+   E +E+I  ++ ++   IN  NL  F  S+  R ++           E +  LKCPAL V G+ +     V+   + L      +P +   L++    G+  V+  +P K+AE+ +YF
Sbjct:  106 IETPH-GVLHVTLRGTPKGNRPVILTYHDIGLNHKSCFNTLFNFEDMQEITQHFAVVHVDAPGQQENAPPFPSGYQYPTMDELAEMLPSVLTQLKINSVIGIGVGAGAYILTRLALNQSTLVEGLVLINVDPCAKGWMDWAASKLSGWTSN-----------LVDIVMGHHFSTDELTENQEIIQTYRLHIAQDINQDNLALFCNSYNGRRDLEIERPILGINEETVNTLKCPALLVVGDTSPAVEAVVECNSRL------NPTKTTLLKMADCGGLPQVV--QPGKLAEAFKYF 380

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BLAST of Protein NDRG4 vs. Ensembl Nematostella
Match: EDO32493 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SUY2])

HSP 1 Score: 146.747 bits (369), Expect = 5.610e-41
Identity = 106/333 (31.83%), Postives = 165/333 (49.55%), Query Frame = 2

Query:   35 MVEIEVKQVTTPKCGVLNIYIQGNRSPNEV----------IIFTIHDLGCNHKE-YEQFLEHTSMKHLRNRCVWIHLDIPGQGDNDEDL-NLKEFPTMQEIADDIKVIFDELNIQHAVLFGEGAGANILARFAMNN--DDKVLGIVLIHCTGTTAGIKEAIRDRLITWKLNTTGMNPVAESYLVVHRFGEHINTNSEKEFREMINGFKRNLQASINPRNLNKFILSFMNRSNI--------AERIYQLKCPALFVTGNLASHNHTVMTLYNTLQKFVKDDPERIKKLELIQVNGVANVLKEKPEKIAESLQYFXXXXXXXXXXRVHSLCNPLS 967
            M E   KQ    K G L +YI+G  + ++           ++ T HDLG NHK  +E+FL H  +K +++R V  HLD PGQ    E+L N  ++PT+ E+AD +  + D   +   V FG G+GANIL   A+ +   +++LG++L+   G T+  KE    ++  W+LN  G      +YL  H    H    + K   E++  F   ++ +INP NL  F+ S+M+R NI         ++        + VTG  + H       +  L       P   KK  +++ +   +VL+EKP+ +AE L  F+QGLGLV  LR  S+    S
Sbjct:    1 MSEETPKQERVEKVGDLTVYIEGEEAKDKTDEKENVKKKDVMITFHDLGMNHKTCFEKFLMHEDIKSIKDRFVIYHLDAPGQETGAENLSNDYQYPTINELADMVGKVLDHFALDDVVCFGVGSGANILCHLALASKWKERILGLILVEPCGATSSFKEWGEAKVKKWQLNAKGFTEGTANYLKWH----HFERKTGKPNIELMENFCDEMKKNINPHNLAAFLNSYMHRPNILNEAKQSVKDKSVSTTAYIMVVTGEHSPHKEQSEQFFRVLS------PVDRKKYSILKPDCGTSVLEEKPDTMAEGLLLFIQGLGLVPTLRTRSMSRTSS 323

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BLAST of Protein NDRG4 vs. Ensembl Nematostella
Match: EDO40164 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S803])

HSP 1 Score: 116.316 bits (290), Expect = 1.024e-29
Identity = 80/271 (29.52%), Postives = 138/271 (50.92%), Query Frame = 2

Query:  128 IFTIHDLGCNHKE-YEQFLEHTSMKHLRNRCVWIHLDIPGQGDNDEDL-NLKEFPTMQEIAD-DIKVIFDELNIQHAVLFGEGAGANILARFAMNNDDKVLGIVLIHCTGTTAGIKEAIRDRLITWKLNTTGMNPVAESYLVVHRFGEHINTNSEKEFREMINGFKRNLQASINPRNLNKFILSFMNRSNI--------AERIYQLKCPALFVTGNLASHNHTVMTLYNTLQKFVKDDPERIKKLELIQVNGVANVLKEKPEKIAESLQYF 907
            I T HD+G NH   +  F     ++ L       H+D PGQ + ++ L     +PTM+E+AD  +  +  +L+I   +  G GAGAN+L R+ +   D V  +VL++ +   +G  E    ++   +L+  G+    E YL+ H FGE     +++E  ++ + +K +L++ +NP NL  FI S++ R+NI              LKCP L VTG  + H   V+   + L      DP+  + +++    G+   L+E+P K+A++L  F
Sbjct:   10 IVTFHDIGQNHTSAFLGFFNFVDVQPLLEHFCIYHIDAPGQENCEKQLPETFVYPTMEELADFVVHEVVKQLSISRFIGLGVGAGANVLCRYGLMYPDFVDALVLVNLSVGKSGWIEWGYQKVCVRQLHNKGLTTFVEDYLLWHHFGE----KTKEENLDLSSAYKDSLRSLLNPHNLALFINSYITRTNIDIVRPVEGGPNPRSLKCPTLLVTGTFSPHGDDVVESNSRL------DPKISEYMKVSDCGGMP--LEEQPAKVAQALILF 268

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BLAST of Protein NDRG4 vs. Ensembl Medaka
Match: ENSORLT00000006023.2 (protein NDRG1 [Source:NCBI gene;Acc:101156766])

HSP 1 Score: 115.931 bits (289), Expect = 7.372e-29
Identity = 78/295 (26.44%), Postives = 142/295 (48.14%), Query Frame = 2

Query:   59 VTTPKCGVLNIYIQGNRSPNEVIIFTIHDLGCNHKE-YEQFLEHTSMKHLRNRCVWIHLDIPGQGDNDEDL-NLKEFPTMQEIADDIKVIFDELNIQHAVLFGEGAGANILARFAMNNDDKVLGIVLIHCTGTTAGIKEAIRDRLITWKLNTTGMNPVAESYLVVHRFG-EHINTNSEKEFREMINGFKRNLQASINPRNLNKFILSFMNRSNIAER---------IYQLKCPALFVTGNLASHNHTVMTLYNTLQKFVKDDPERIKKLELIQVNGVANVLKEKPEKIAESLQYF 907
            V TP  G L+  + G    N  +I T HD+G NHK  +E    H  M+ +       H++ PGQ +  + L  L  +PT+ ++++ +  +     ++  +  G GAGA ILARFA+N+ D V G+VLI+      G+ +++ +++  W              L+ H FG E I  N      +++  ++  + A++N  N+++F  S+ NR+ +  +         +  LKC  L V G+ +     V+   + L      +P +   L++    G+  V  ++P K+ E+L+YF
Sbjct:   21 VETPY-GDLHCIMTGTPKANRPVILTFHDVGLNHKSCFETLFNHEDMQEIVKHLPVCHVEAPGQQEAAKSLPTLYTYPTVDQLSEALPAVLKNFGLRSVIGLGVGAGAYILARFALNHPDLVDGLVLINVNPNAEGLMDSVANKITDW-------TQTLPDKLIAHLFGQEEIQKN-----YDLVATYRHYITATMNQSNVSQFFRSYNNRTTLDVQRPVSGGNINVRTLKCSTLLVVGDNSPAVEAVVDCNSKL------NPNKTTLLKMADCGGLPQV--DQPAKVTEALKYF 294

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BLAST of Protein NDRG4 vs. Ensembl Medaka
Match: ndrg3a (NDRG family member 3 [Source:NCBI gene;Acc:101162117])

HSP 1 Score: 112.849 bits (281), Expect = 8.838e-28
Identity = 80/295 (27.12%), Postives = 133/295 (45.08%), Query Frame = 2

Query:   59 VTTPKCGVLNIYIQGNRSPNEVIIFTIHDLGCNHKE-YEQFLEHTSMKHLRNRCVWIHLDIPGQGDNDEDLNLK-EFPTMQEIADDIKVIFDELNIQHAVLFGEGAGANILARFAMNNDDKVLGIVLIHCTGTTAGIKEAIRDRLITWKLNTTGMNPVAESYLVVHRFGEHINTNSEKEFREMINGFKRNLQASINPRNLNKFILSFMNRSNIA----------ERIYQLKCPALFVTGNLASHNHTVMTLYNTLQKFVKDDPERIKKLELIQVNGVANVLKEKPEKIAESLQYF 907
            + TP  GVL++ ++G    N  +I T HD+G NHK  +     +  M+ +      +H+D PGQ +          +PTM E+++ +  +   L I   +  G GAG+ IL RFA+NN   V G+VLI       G  +    +L  W  N           LV      H +T+   E +E+I  ++ ++   IN  NL  F  S+  R ++           + +  L CPAL V G+ +     V+   + L      +P +   L++    G+  V+  +P K+AE+ +YF
Sbjct:   21 IETPH-GVLHVTMRGVPKGNRPVILTYHDIGLNHKSCFNTLFNYEDMQEITQHFAVVHVDAPGQQEGAPPFPTGYRYPTMDELSEMLPSVMTRLKINSVIGIGVGAGSYILTRFALNNPALVEGLVLIDVDPCAEGWIDWAASKLSGWTSN-----------LVDIVMAHHFSTDELTENQELIQTYRLHIAQDINQDNLALFCGSYQYRQDLGIERPVVGLNEDTVNTLTCPALLVVGDTSPAVEAVVECNSRL------NPTKTTLLKMADCGGLPQVV--QPGKLAEAFKYF 295

[Close]

BLAST of Protein NDRG4 vs. Ensembl Medaka
Match: ndrg3a (NDRG family member 3 [Source:NCBI gene;Acc:101162117])

HSP 1 Score: 113.235 bits (282), Expect = 9.043e-28
Identity = 80/295 (27.12%), Postives = 133/295 (45.08%), Query Frame = 2

Query:   59 VTTPKCGVLNIYIQGNRSPNEVIIFTIHDLGCNHKE-YEQFLEHTSMKHLRNRCVWIHLDIPGQGDNDEDLNLK-EFPTMQEIADDIKVIFDELNIQHAVLFGEGAGANILARFAMNNDDKVLGIVLIHCTGTTAGIKEAIRDRLITWKLNTTGMNPVAESYLVVHRFGEHINTNSEKEFREMINGFKRNLQASINPRNLNKFILSFMNRSNIA----------ERIYQLKCPALFVTGNLASHNHTVMTLYNTLQKFVKDDPERIKKLELIQVNGVANVLKEKPEKIAESLQYF 907
            + TP  GVL++ ++G    N  +I T HD+G NHK  +     +  M+ +      +H+D PGQ +          +PTM E+++ +  +   L I   +  G GAG+ IL RFA+NN   V G+VLI       G  +    +L  W  N           LV      H +T+   E +E+I  ++ ++   IN  NL  F  S+  R ++           + +  L CPAL V G+ +     V+   + L      +P +   L++    G+  V+  +P K+AE+ +YF
Sbjct:   34 IETPH-GVLHVTMRGVPKGNRPVILTYHDIGLNHKSCFNTLFNYEDMQEITQHFAVVHVDAPGQQEGAPPFPTGYRYPTMDELSEMLPSVMTRLKINSVIGIGVGAGSYILTRFALNNPALVEGLVLIDVDPCAEGWIDWAASKLSGWTSN-----------LVDIVMAHHFSTDELTENQELIQTYRLHIAQDINQDNLALFCGSYQYRQDLGIERPVVGLNEDTVNTLTCPALLVVGDTSPAVEAVVECNSRL------NPTKTTLLKMADCGGLPQVV--QPGKLAEAFKYF 308

[Close]

BLAST of Protein NDRG4 vs. Ensembl Medaka
Match: ndrg3a (NDRG family member 3 [Source:NCBI gene;Acc:101162117])

HSP 1 Score: 112.849 bits (281), Expect = 1.200e-27
Identity = 80/295 (27.12%), Postives = 133/295 (45.08%), Query Frame = 2

Query:   59 VTTPKCGVLNIYIQGNRSPNEVIIFTIHDLGCNHKE-YEQFLEHTSMKHLRNRCVWIHLDIPGQGDNDEDLNLK-EFPTMQEIADDIKVIFDELNIQHAVLFGEGAGANILARFAMNNDDKVLGIVLIHCTGTTAGIKEAIRDRLITWKLNTTGMNPVAESYLVVHRFGEHINTNSEKEFREMINGFKRNLQASINPRNLNKFILSFMNRSNIA----------ERIYQLKCPALFVTGNLASHNHTVMTLYNTLQKFVKDDPERIKKLELIQVNGVANVLKEKPEKIAESLQYF 907
            + TP  GVL++ ++G    N  +I T HD+G NHK  +     +  M+ +      +H+D PGQ +          +PTM E+++ +  +   L I   +  G GAG+ IL RFA+NN   V G+VLI       G  +    +L  W  N           LV      H +T+   E +E+I  ++ ++   IN  NL  F  S+  R ++           + +  L CPAL V G+ +     V+   + L      +P +   L++    G+  V+  +P K+AE+ +YF
Sbjct:   34 IETPH-GVLHVTMRGVPKGNRPVILTYHDIGLNHKSCFNTLFNYEDMQEITQHFAVVHVDAPGQQEGAPPFPTGYRYPTMDELSEMLPSVMTRLKINSVIGIGVGAGSYILTRFALNNPALVEGLVLIDVDPCAEGWIDWAASKLSGWTSN-----------LVDIVMAHHFSTDELTENQELIQTYRLHIAQDINQDNLALFCGSYQYRQDLGIERPVVGLNEDTVNTLTCPALLVVGDTSPAVEAVVECNSRL------NPTKTTLLKMADCGGLPQVV--QPGKLAEAFKYF 308

[Close]

BLAST of Protein NDRG4 vs. Ensembl Medaka
Match: NDRG3 (protein NDRG3 [Source:NCBI gene;Acc:101163152])

HSP 1 Score: 110.153 bits (274), Expect = 7.853e-27
Identity = 78/289 (26.99%), Postives = 134/289 (46.37%), Query Frame = 2

Query:   77 GVLNIYIQGNRSPNEVIIFTIHDLGCNHKE-YEQFLEHTSMKHLRNRCVWIHLDIPGQGDNDEDLNLK-EFPTMQEIADDIKVIFDELNIQHAVLFGEGAGANILARFAMNNDDKVLGIVLIHCTGTTAGIKEAIRDRLITWKLNTTGMNPVAESYLVVHRFGEHINTNSEKEFREMINGFKRNLQASINPRNLNKFILSFMNRSNIA-ER---------IYQLKCPALFVTGNLASHNHTVMTLYNTLQKFVKDDPERIKKLELIQVNGVANVLKEKPEKIAESLQYF 907
            GVL++ ++G    N   I T HD+G NHK  +     +  M  +      +H+D PGQ +N        ++PTM E+A+ +  +  +L I+  +  G GAGA IL R A+N    V G+VLI+      G  +    +L  W  N           LV    G H +++   E +E+I  ++ ++   +   NL  F  S+ +R+ +  ER         +  L+CPAL V G+ +     V+   + +      +P +   L++    G+  V+  +P K+AE+ +YF
Sbjct:   27 GVLHVTMRGVAKGNRPTILTYHDIGLNHKSCFNSLFNYEDMLEVTQHFSVLHVDAPGQQENAPVFPTGYQYPTMDELAEMLPSVLTQLQIKSVIGIGVGAGAYILTRLALNEPGLVEGLVLINVDPCAKGWVDWAASKLSGWTSN-----------LVDIIMGHHFSSDELTENKEIIQTYRLHISQDVPQENLAMFYNSYDSRTELQMERPVAGLNENTVTTLRCPALLVVGDTSPAVDAVVECNSRM------NPTKTTLLKMADCGGLPQVV--QPGKLAEAFKYF 296

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BLAST of Protein NDRG4 vs. Planmine SMEST
Match: SMESG000065324.1 (SMESG000065324.1)

HSP 1 Score: 335.88 bits (860), Expect = 6.307e-114
Identity = 173/319 (54.23%), Postives = 226/319 (70.85%), Query Frame = 2

Query:   68 PKCGVLNIYIQGNRSPNEVIIFTIHDLGCNHKEYEQFLEHTSMKHLRNRCVWIHLDIPGQGDNDEDLNLKEFPTMQEIADDIKVIFDELNIQHAVLFGEGAGANILARFAMNNDDKVLGIVLIHCTGTTAGIKEAIRDRLITWKLNTTGMNPVAESYLVVHRFGEHINTNSEKEFREMINGFKRNLQASINPRNLNKFILSFMNRSNIAERIYQLKCPALFVTGNLASHNHTVMTLYNTLQKFVKDDPERIKKLELIQVNGVANVLKEKPEKIAESLQYFXXXXXXXXXXRVHSLCNPLSRRLSMEQLDLPRGPDSLSS 1024
            PK G +N+YIQG R P E II T+HDLGCNH +YE+FL +  M  L  + VWIH+D+PGQGD DEDL    FP+M++IA D++ +  ++ + + +LFGEGAGANILARFA+N++  VLG +LIHC G+TA + E+++D++I WKLN+ GMNP AESYLV+HRFG   N  +E E + +I  FK NL+ SINP+NL KFI SFM R N+ ERI +L  P LF+TG  A H   V  L  TL K  K   +++ K EL+Q++GVANVL E PEK+  SLQYFLQGLGLV  LR+ +    ++RR+SME  D PRG  S SS
Sbjct:   15 PKMGAINVYIQGTRGPKEQIILTVHDLGCNHYQYEEFLSNPKMSALSQKFVWIHVDLPGQGDGDEDLE-TNFPSMEDIALDLQELCVQMKLSNVLLFGEGAGANILARFAINSEHLVLGAILIHCVGSTASMIESLKDKVINWKLNSIGMNPTAESYLVLHRFGTFKNAENETELKNVIESFKYNLRNSINPKNLYKFINSFMTRRNLGERIAKLNTPTLFITGAAAIHCKNVHLLQETLLK-TKPADQKV-KFELVQIDGVANVLTEAPEKVVVSLQYFLQGLGLVSNLRLSNEPIKINRRMSMEDYDRPRGTGSFSS 330

[Close]

BLAST of Protein NDRG4 vs. Planmine SMEST
Match: SMESG000065324.1 (SMESG000065324.1)

HSP 1 Score: 331.257 bits (848), Expect = 5.187e-112
Identity = 173/323 (53.56%), Postives = 226/323 (69.97%), Query Frame = 2

Query:   68 PKCGVLNIYIQGNRSPNEVIIFTIHDLGCNHKEYEQFLEHTSMKHLRNRCVWIHLDIPGQGDNDEDLNLKEFPTMQEIADDIKVIFDELNIQHAVLFGEGAGANILARFAMNNDDKVLGIVLIHCTGTTAGIKEAIRDRLITWKLNTTGMNPVAESYLVVHRFGEHI----NTNSEKEFREMINGFKRNLQASINPRNLNKFILSFMNRSNIAERIYQLKCPALFVTGNLASHNHTVMTLYNTLQKFVKDDPERIKKLELIQVNGVANVLKEKPEKIAESLQYFXXXXXXXXXXRVHSLCNPLSRRLSMEQLDLPRGPDSLSS 1024
            PK G +N+YIQG R P E II T+HDLGCNH +YE+FL +  M  L  + VWIH+D+PGQGD DEDL    FP+M++IA D++ +  ++ + + +LFGEGAGANILARFA+N++  VLG +LIHC G+TA + E+++D++I WKLN+ GMNP AESYLV+HRFG       N  +E E + +I  FK NL+ SINP+NL KFI SFM R N+ ERI +L  P LF+TG  A H   V  L  TL K  K   +++ K EL+Q++GVANVL E PEK+  SLQYFLQGLGLV  LR+ +    ++RR+SME  D PRG  S SS
Sbjct:   15 PKMGAINVYIQGTRGPKEQIILTVHDLGCNHYQYEEFLSNPKMSALSQKFVWIHVDLPGQGDGDEDLE-TNFPSMEDIALDLQELCVQMKLSNVLLFGEGAGANILARFAINSEHLVLGAILIHCVGSTASMIESLKDKVINWKLNSIGMNPTAESYLVLHRFGTQSIKFKNAENETELKNVIESFKYNLRNSINPKNLYKFINSFMTRRNLGERIAKLNTPTLFITGAAAIHCKNVHLLQETLLK-TKPADQKV-KFELVQIDGVANVLTEAPEKVVVSLQYFLQGLGLVSNLRLSNEPIKINRRMSMEDYDRPRGTGSFSS 334

[Close]

BLAST of Protein NDRG4 vs. Planmine SMEST
Match: SMESG000021236.1 (SMESG000021236.1)

HSP 1 Score: 306.605 bits (784), Expect = 1.627e-102
Identity = 146/326 (44.79%), Postives = 226/326 (69.33%), Query Frame = 2

Query:   59 VTTPKCGVLNIYIQGNRSPNEVIIFTIHDLGCNHKEYEQFLEHTSMKHLRNRCVWIHLDIPGQGDNDEDL-NLKEFPTMQEIADDIKVIFDELNIQHAVLFGEGAGANILARFAMNNDDKVLGIVLIHCTGTTAGIKEAIRDRLITWKLNTTGMNPVAESYLVVHRFGEHINTNSEKEFREMINGFKRNLQASINPRNLNKFILSFMNRSNIAERIYQLKCPALFVTGNLASHNHTVMTLYNTLQKFVKDDPERIKKLELIQVNGVANVLKEKPEKIAESLQYFXX---XXXXXXXXRVHSLCNPLS-RRLSMEQLDLPRGPDSLS 1021
            + T  CG L  YI+G RS NEV I T+HD+GCNH +Y  FL+H+SM+ L  RCVW ++ +PGQ  ND DL +   +PTMQ+IADD+      L+I H ++FGEGAGANILAR AM+ D+++LG VL++C G+T  + E+++D++I WKL+T GM    E+YLVVHRFG   N  S+++   MIN +K+ L+ + N +NL+ ++ S+MNRSN+ ++   ++CP LF++G+LA++   V  LY  +Q F+K++P+R + +E ++++  ANVL E+ +++AESLQYFLQ    +G     R+ S   P+  R++SME+ D P+G  +++
Sbjct:    4 INTKYCGKLTFYIEGTRSTNEVAILTVHDIGCNHTQYIDFLKHSSMETLAPRCVWFNVVLPGQSVNDPDLPSDYTYPTMQQIADDLIECIGILSISHLIVFGEGAGANILARMAMSGDERILGAVLLNCVGSTPNLVESLKDKIIGWKLSTIGMTSSTENYLVVHRFGVMNNLESDEDLSTMINNYKKFLRDTFNSKNLHGYVTSYMNRSNLIDKNMTIRCPILFISGSLANYADDVKCLYEDIQGFLKNEPDRKRHIEFMEIDNCANVLVERTDQVAESLQYFLQGQGLVGSAPSRRMSSTVRPIGNRKISMEEYDSPKGASNIT 329

[Close]

BLAST of Protein NDRG4 vs. Planmine SMEST
Match: SMESG000021236.1 (SMESG000021236.1)

HSP 1 Score: 290.426 bits (742), Expect = 1.457e-95
Identity = 150/364 (41.21%), Postives = 228/364 (62.64%), Query Frame = 2

Query:   59 VTTPKCGVLNIYIQGNRSPNEVIIFTIHDLGCNHKEYEQFLEHTSMKHLRNRCVWIHLDIPGQGDNDEDL-NLKEFPTMQEIADDIKVIFDELNIQHAVLFGEGAGANILARFAMNNDDKVLGIVLIHCTGTTAGIKEAIRDRLITWKLNTTGMNPVAESYLVVHRFGEHINTNSEKEFREMINGFKRNLQASINPRNLNKFILSFMNRSNIAER---IYQ-----------------------------------LKCPALFVTGNLASHNHTVMTLYNTLQKFVKDDPERIKKLELIQVNGVANVLKEKPEKIAESLQYFXXXX---XXXXXXRVHSLCNPLS-RRLSMEQLDLPRGPDSLS 1021
            + T  CG L  YI+G RS NEV I T+HD+GCNH +Y  FL+H+SM+ L  RCVW ++ +PGQ  ND DL +   +PTMQ+IADD+      L+I H ++FGEGAGANILAR AM+ D+++LG VL++C G+T  + E+++D++I WKL+T GM    E+YLVVHRFG   N  S+++   MIN +K+ L+ + N +NL+ ++ S+MNRSN+ ++   I Q                                   +KCP LF++G+LA++   V  LY  +Q F+K++P+R + +E ++++  ANVL E+ +++AESLQYFLQG    G     R+ S   P+  R++SME+ D P+G  +++
Sbjct:    4 INTKYCGKLTFYIEGTRSTNEVAILTVHDIGCNHTQYIDFLKHSSMETLAPRCVWFNVVLPGQSVNDPDLPSDYTYPTMQQIADDLIECIGILSISHLIVFGEGAGANILARMAMSGDERILGAVLLNCVGSTPNLVESLKDKIIGWKLSTIGMTSSTENYLVVHRFGVMNNLESDEDLSTMINNYKKFLRDTFNSKNLHGYVTSYMNRSNLIDKNMTISQDISDSRQEDKQKVKKGKYREMEAETRERKSSKCPAIKCPILFISGSLANYADDVKCLYEDIQGFLKNEPDRKRHIEFMEIDNCANVLVERTDQVAESLQYFLQGQGLVGSAPSRRMSSTVRPIGNRKISMEEYDSPKGASNIT 367

[Close]

BLAST of Protein NDRG4 vs. Planmine SMEST
Match: SMESG000055204.1 (SMESG000055204.1)

HSP 1 Score: 255.758 bits (652), Expect = 1.342e-85
Identity = 120/123 (97.56%), Postives = 123/123 (100.00%), Query Frame = 2

Query:   35 MVEIEVKQVTTPKCGVLNIYIQGNRSPNEVIIFTIHDLGCNHKEYEQFLEHTSMKHLRNRCVWIHLDIPGQGDNDEDLNLKEFPTMQEIADDIKVIFDELNIQHAVLFGEGAGANILARFAMN 403
            MVEIEVKQVTTPKCGVLNIYIQGNRSPNEVIIFTIHDLGCNHKEYEQFLEHTSMKH+RNRCVWIHLDIPGQGDNDEDLNLKEFPTMQEIADDIKVIFDELNIQHAVLFGEGAGANILARFA++
Sbjct:    1 MVEIEVKQVTTPKCGVLNIYIQGNRSPNEVIIFTIHDLGCNHKEYEQFLEHTSMKHIRNRCVWIHLDIPGQGDNDEDLNLKEFPTMQEIADDIKVIFDELNIQHAVLFGEGAGANILARFAVS 123

The following BLAST results are available for this feature:

BLAST of Protein NDRG4 vs. Ensembl Human
BLAST of Protein NDRG4 vs. Ensembl Celegans
BLAST of Protein NDRG4 vs. Ensembl Fly
BLAST of Protein NDRG4 vs. Ensembl Zebrafish
BLAST of Protein NDRG4 vs. Ensembl Xenopus
BLAST of Protein NDRG4 vs. Ensembl Mouse
BLAST of Protein NDRG4 vs. UniProt/SwissProt
BLAST of Protein NDRG4 vs. TrEMBL
BLAST of Protein NDRG4 vs. Ensembl Cavefish
BLAST of Protein NDRG4 vs. Ensembl Sea Lamprey
BLAST of Protein NDRG4 vs. Ensembl Yeast
BLAST of Protein NDRG4 vs. Ensembl Nematostella
BLAST of Protein NDRG4 vs. Ensembl Medaka
BLAST of Protein NDRG4 vs. Planmine SMEST

BLAST of Protein NDRG4 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5


Match Name	E-value	Identity	Description
NDRG1	1.706e-27	26.13	N-myc downstream regulated 1 [Source:HGNC Symbol;A...	[more]
NDRG1	1.706e-27	26.13	N-myc downstream regulated 1 [Source:HGNC Symbol;A...	[more]
NDRG2	7.022e-24	27.34	NDRG family member 2 [Source:HGNC Symbol;Acc:HGNC:...	[more]
NDRG2	1.632e-23	26.96	NDRG family member 2 [Source:HGNC Symbol;Acc:HGNC:...	[more]
NDRG2	1.632e-23	26.96	NDRG family member 2 [Source:HGNC Symbol;Acc:HGNC:...	[more]

BLAST of Protein NDRG4 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 3


Match Name	E-value	Identity	Description
ZK1073.1	2.165e-69	36.99	pep chromosome:WBcel235:X:16124151:16128865:-1 gen...	[more]
ZK1073.1	2.165e-69	36.99	pep chromosome:WBcel235:X:16123942:16128815:-1 gen...	[more]
Y48G10A.3	9.932e-28	26.67	pep chromosome:WBcel235:I:13471683:13474185:-1 gen...	[more]

BLAST of Protein NDRG4 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5


Match Name	E-value	Identity	Description
CG2082	4.335e-56	31.36	gene:FBgn0027608 transcript:FBtr0078672	[more]
CG2082	4.335e-56	31.36	gene:FBgn0027608 transcript:FBtr0300909	[more]
CG2082	6.749e-56	31.36	gene:FBgn0027608 transcript:FBtr0078675	[more]
CG2082	2.042e-55	30.80	gene:FBgn0027608 transcript:FBtr0300911	[more]
CG2082	2.042e-55	30.80	gene:FBgn0027608 transcript:FBtr0300907	[more]

BLAST of Protein NDRG4 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5


Match Name	E-value	Identity	Description
ndrg3b	3.254e-28	27.80	ndrg family member 3b [Source:ZFIN;Acc:ZDB-GENE-03...	[more]
ndrg3b	3.254e-28	27.80	ndrg family member 3b [Source:ZFIN;Acc:ZDB-GENE-03...	[more]
ndrg1b	1.243e-27	26.64	N-myc downstream regulated 1b [Source:ZFIN;Acc:ZDB...	[more]
ndrg3b	1.382e-27	27.27	ndrg family member 3b [Source:ZFIN;Acc:ZDB-GENE-03...	[more]
ndrg3a	3.912e-26	27.12	ndrg family member 3a [Source:ZFIN;Acc:ZDB-GENE-98...	[more]

BLAST of Protein NDRG4 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5


Match Name	E-value	Identity	Description
kif1a	7.134e-26	26.64	kinesin family member 1A [Source:Xenbase;Acc:XB-GE...	[more]
kif1a	8.544e-26	26.64	kinesin family member 1A [Source:Xenbase;Acc:XB-GE...	[more]
slc15a5	1.485e-23	25.78	solute carrier family 15, member 5 [Source:Xenbase...	[more]
slc15a5	1.546e-23	25.78	solute carrier family 15, member 5 [Source:Xenbase...	[more]
slc15a5	1.577e-23	25.78	solute carrier family 15, member 5 [Source:Xenbase...	[more]

BLAST of Protein NDRG4 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5


Match Name	E-value	Identity	Description
Ndrg1	6.135e-28	26.48	N-myc downstream regulated gene 1 [Source:MGI Symb...	[more]
Ndrg2	1.670e-25	27.99	N-myc downstream regulated gene 2 [Source:MGI Symb...	[more]
Ndrg2	1.694e-25	28.37	N-myc downstream regulated gene 2 [Source:MGI Symb...	[more]
Ndrg3	8.064e-24	26.35	N-myc downstream regulated gene 3 [Source:MGI Symb...	[more]
Ndrg3	8.765e-24	26.35	N-myc downstream regulated gene 3 [Source:MGI Symb...	[more]

BLAST of Protein NDRG4 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5


Match Name	E-value	Identity	Description
sp\|O02485\|YDJ1_CAEEL	2.753e-68	36.99	Uncharacterized protein ZK1073.1 OS=Caenorhabditis...	[more]
sp\|Q6JE36\|NDRG1_RAT	2.180e-27	26.48	Protein NDRG1 OS=Rattus norvegicus OX=10116 GN=Ndr...	[more]
sp\|Q62433\|NDRG1_MOUSE	4.292e-27	26.48	Protein NDRG1 OS=Mus musculus OX=10090 GN=Ndrg1 PE...	[more]
sp\|Q92597\|NDRG1_HUMAN	8.193e-27	26.13	Protein NDRG1 OS=Homo sapiens OX=9606 GN=NDRG1 PE=...	[more]
sp\|Q4R4Q3\|NDRG1_MACFA	8.526e-27	26.13	Protein NDRG1 OS=Macaca fascicularis OX=9541 GN=Nd...	[more]

BLAST of Protein NDRG4 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5


Match Name	E-value	Identity	Description
C1L4M7	4.580e-116	55.48	Uncharacterized protein OS=Schistosoma japonicum O...	[more]
C7TZF8	4.591e-116	53.80	Uncharacterized protein OS=Schistosoma japonicum O...	[more]
A0A3Q0KUE1	7.417e-116	53.80	Family S33 non-peptidase homologue (S33 family) OS...	[more]
Q5DF09	9.421e-116	53.66	SJCHGC02626 protein OS=Schistosoma japonicum OX=61...	[more]
A0A4Z2D724	8.239e-115	55.14	Uncharacterized protein OS=Schistosoma japonicum O...	[more]

BLAST of Protein NDRG4 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5


Match Name	E-value	Identity	Description
ndrg3b	1.764e-30	28.47	ndrg family member 3b [Source:ZFIN;Acc:ZDB-GENE-03...	[more]
ndrg3b	4.752e-30	28.47	ndrg family member 3b [Source:ZFIN;Acc:ZDB-GENE-03...	[more]
ndrg3b	5.538e-30	28.47	ndrg family member 3b [Source:ZFIN;Acc:ZDB-GENE-03...	[more]
ndrg3b	6.460e-30	28.47	ndrg family member 3b [Source:ZFIN;Acc:ZDB-GENE-03...	[more]
ndrg3b	6.465e-30	28.47	ndrg family member 3b [Source:ZFIN;Acc:ZDB-GENE-03...	[more]

BLAST of Protein NDRG4 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 0


Match Name	E-value	Identity	Description

BLAST of Protein NDRG4 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0


Match Name	E-value	Identity	Description

BLAST of Protein NDRG4 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 2


Match Name	E-value	Identity	Description
EDO32493	5.610e-41	31.83	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO40164	1.024e-29	29.52	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]

BLAST of Protein NDRG4 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5


Match Name	E-value	Identity	Description
ENSORLT00000006023.2	7.372e-29	26.44	protein NDRG1 [Source:NCBI gene;Acc:101156766]	[more]
ndrg3a	8.838e-28	27.12	NDRG family member 3 [Source:NCBI gene;Acc:1011621...	[more]
ndrg3a	9.043e-28	27.12	NDRG family member 3 [Source:NCBI gene;Acc:1011621...	[more]
ndrg3a	1.200e-27	27.12	NDRG family member 3 [Source:NCBI gene;Acc:1011621...	[more]
NDRG3	7.853e-27	26.99	protein NDRG3 [Source:NCBI gene;Acc:101163152]	[more]

BLAST of Protein NDRG4 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5


Match Name	E-value	Identity	Description
SMESG000065324.1	6.307e-114	54.23	SMESG000065324.1	[more]
SMESG000065324.1	5.187e-112	53.56	SMESG000065324.1	[more]
SMESG000021236.1	1.627e-102	44.79	SMESG000021236.1	[more]
SMESG000021236.1	1.457e-95	41.21	SMESG000021236.1	[more]
SMESG000055204.1	1.342e-85	97.56	SMESG000055204.1	[more]

Analyses

This transcript is derived from or has results from the following analyses


Analysis Name	Date Performed
Embryonic Stages	2016-07-25
Schmidtea mediterranea smed_20140614 BLASTX Human e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL	2020-05-01
Schmidtea mediterranea Sexual smed_20140614 transcriptome	2016-07-25
Schmidtea mediteranean smed_20140614 Interproscan	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST	2020-05-08

Sequences

The following sequences are available for this feature:

transcript sequence
protein sequence

transcript sequence

>SMED30013306 ID=SMED30013306|Name=Protein NDRG4|organism=Schmidtea mediterranea sexual|type=transcript|length=1127bp
CTAATACGAATTTAAGATTCTATTTCGTTGAAATATGGTTGAAATTGAAG
TTAAGCAAGTTACTACTCCTAAATGTGGAGTTCTTAATATTTATATTCAA
GGAAACAGGTCGCCAAATGAAGTTATTATATTTACCATTCATGATCTTGG
TTGTAATCATAAAGAATATGAACAATTTCTTGAACACACTTCAATGAAGC
ACCTTAGAAATCGATGCGTTTGGATTCATTTGGATATTCCTGGGCAAGGG
GATAACGATGAAGATTTGAACTTAAAAGAATTTCCAACGATGCAAGAAAT
TGCTGATGATATAAAAGTAATTTTTGACGAATTAAATATTCAGCATGCTG
TGCTGTTTGGTGAAGGAGCCGGAGCTAATATTCTTGCGCGATTTGCTATG
AACAATGATGATAAAGTCTTGGGAATTGTTTTGATTCATTGTACAGGAAC
AACTGCGGGTATAAAAGAGGCGATTAGGGATCGATTAATCACCTGGAAAC
TGAATACAACTGGCATGAATCCAGTTGCAGAAAGCTATTTGGTTGTTCAC
AGATTCGGGGAACATATAAATACTAATAGTGAGAAAGAGTTTCGGGAAAT
GATAAATGGGTTCAAGAGAAATTTGCAAGCCTCTATTAATCCTAGAAATC
TCAACAAATTCATTTTGTCGTTTATGAACCGTTCTAATATTGCGGAGAGG
ATTTATCAATTGAAATGCCCAGCCTTATTTGTGACTGGAAACCTCGCATC
TCACAACCACACTGTTATGACTTTATATAATACGTTGCAAAAATTTGTTA
AAGATGATCCTGAACGTATTAAGAAGCTCGAATTGATCCAGGTCAATGGA
GTTGCTAATGTATTAAAAGAAAAACCAGAGAAAATCGCGGAATCATTACA
ATATTTCCTTCAAGGTTTAGGATTAGTTGGTGGATTACGAGTTCACAGCT
TATGCAATCCGTTATCAAGGCGATTATCCATGGAACAGCTTGACTTGCCA
CGAGGACCAGATTCGCTATCCTCCATCCGAAAAGGATCAATGCCAATTCA
ACATTAAAAAAATTATCTAATTTCATTACTAGTTAGAGTTGATGATTAAA
ACCCACTAAACATTTTCATAATTTATG

protein sequence of SMED30013306-orf-1

>SMED30013306-orf-1 ID=SMED30013306-orf-1|Name=SMED30013306-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=341bp
MVEIEVKQVTTPKCGVLNIYIQGNRSPNEVIIFTIHDLGCNHKEYEQFLE
HTSMKHLRNRCVWIHLDIPGQGDNDEDLNLKEFPTMQEIADDIKVIFDEL
NIQHAVLFGEGAGANILARFAMNNDDKVLGIVLIHCTGTTAGIKEAIRDR
LITWKLNTTGMNPVAESYLVVHRFGEHINTNSEKEFREMINGFKRNLQAS
INPRNLNKFILSFMNRSNIAERIYQLKCPALFVTGNLASHNHTVMTLYNT
LQKFVKDDPERIKKLELIQVNGVANVLKEKPEKIAESLQYFLQGLGLVGG
LRVHSLCNPLSRRLSMEQLDLPRGPDSLSSIRKGSMPIQH*

Annotated Terms

The following terms have been associated with this transcript:

Vocabulary: **molecular function**
Term	Definition
GO:0003674	molecular_function
GO:0008017	microtubule binding
GO:0017137	Rab GTPase binding
GO:0043015	gamma-tubulin binding
GO:0045296	cadherin binding

Vocabulary: **cellular component**
Term	Definition
GO:0005575	cellular_component
GO:0005634	nucleus
GO:0005737	cytoplasm
GO:0005813	centrosome
GO:0005815	microtubule organizing center
GO:0005829	cytosol
GO:0005856	cytoskeleton
GO:0005874	microtubule
GO:0005886	plasma membrane
GO:0005913	cell-cell adherens junction
GO:0015630	microtubule cytoskeleton
GO:0016020	membrane
GO:0043209	myelin sheath
GO:0048471	perinuclear region of cytoplasm
GO:0055038	recycling endosome membrane
GO:0070062	extracellular exosome

Vocabulary: **biological process**
Term	Definition
GO:0008150	biological_process
GO:0008285	negative regulation of cell proliferation
GO:0030330	DNA damage response, signal transduction by p53 class mediator
GO:0032287	peripheral nervous system myelin maintenance
GO:0042127	regulation of cell proliferation
GO:0045576	mast cell activation
GO:0071456	cellular response to hypoxia
GO:0090232	positive regulation of spindle checkpoint

Vocabulary: **Planarian Anatomy**
Term	Definition
PLANA:0000099	neuron
PLANA:0000418	head

Vocabulary: **INTERPRO**
Term	Definition
IPR004142	NDRG
IPR029058	AB_hydrolase

InterPro

Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01


IPR Term	IPR Description	Source	Source Term	Source Description	Alignment
IPR004142	NDRG	PFAM	PF03096	Ndr	coord: 10..298 e-value: 4.7E-73 score: 245.4
IPR004142	NDRG	PANTHER	PTHR11034	N-MYC DOWNSTREAM REGULATED	coord: 7..323
IPR029058	Alpha/Beta hydrolase fold	GENE3D	G3DSA:3.40.50.1820		coord: 1..294 e-value: 2.6E-64 score: 219.4
IPR029058	Alpha/Beta hydrolase fold	SUPERFAMILY	SSF53474	alpha/beta-Hydrolases	coord: 15..236
None	No IPR available	PANTHER	PTHR11034:SF40	BCDNA.GH02439	coord: 7..323

Main menu

Protein NDRG4

Zeng et. al., 2018

▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Overview

Single cell RNA-seq of pluripotent neoblasts and its early progenies

Explore this single cell expression dataset with our NB Cluster Shiny App

Neoblast Population

Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Davies et. al., 2017

PAGE et. al., 2020

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE

PAGE Curations: 5

Owlery

blazegraph-runner