TNF receptor-associated factor
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Overview
Neoblast Clusters
Zeng et. al., 2018▻ Overview▻ Neoblast Population▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Overview
Single cell RNA-seq of pluripotent neoblasts and its early progeniesWe isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)Explore this single cell expression dataset with our NB Cluster Shiny App
Neoblast Population
Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Embryonic Expression
Davies et. al., 2017
Hover the mouse over a column in the graph to view average RPKM values per sample. Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult. back to top Anatomical Expression
PAGE et. al., 2020SMED30013205 has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGEPAGE Curations: 17Note: Hover over icons to view figure legend
Homology
BLAST of TNF receptor-associated factor vs. Ensembl Human
Match: TRAF3 (TNF receptor associated factor 3 [Source:HGNC Symbol;Acc:HGNC:12033]) HSP 1 Score: 156.377 bits (394), Expect = 3.629e-39 Identity = 129/456 (28.29%), Postives = 218/456 (47.81%), Query Frame = 2
Query: 1397 IEARLRCGACTKLLKEPRQTECGCRLCTECIIELTLNGPKQCPDCKETEIASLGETQEDRAASREIMNMRIKCPN--KPCNWEGKIREASAHL-NQCRYKRKPCEK--CQQPISESEEKQH-ENVCEERRTRCEYCN-----ITETWKQIQQEHVNVKEEKICDRFRGKCPNKCGVEEEIELKEHWERCSRKRIECPMAKWGCKIKILREETIQHVQETAEEHLKIWXXXXXXXXXX---XXXXXXEIESHKILMTEIFNTRESF-ELAR-IGMSETEKNVENEMKRLREHYQKLRSYTPTGENPPIAPY----IWRIEEFTRKWQRARDGTEVSITSPPFYSWKNGYKLRMRVYPNGDGAGKDTHVSVFFVLVKGEWDELQSWPFSNKMAFTIM---SAKDAHVERLKPD-GAPCYNKPTADVGTAIGSPRIMRQNVM--WEYLEGDTLFVKWSV 2686
+E + +C C +L P+QTECG R C C+ L + +C C+E+ + + +D REI+ ++I C N + C + + HL N C ++ PC + C++ + + + H E C+ R C +C I +Q E +V++ K + C E EIE ++ R + +I +Q V ++ E LK ++ Q +K +ES + +TE+ + +S ++AR G+ E++ + ++M L H +L + A Y IW+I ++ R+ Q A G +S+ S PFY+ GYK+ RVY NGDG GK TH+S+FFV+++GE+D L WPF K+ +M S++ + KPD + + KPT ++ A G P + Q V+ Y++ DT+F+K V
Sbjct: 47 VEDKYKCEKCHLVLCSPKQTECGHRFCESCMAALLSSSSPKCTACQESIVKD--KVFKDNCCKREILALQIYCRNESRGCAEQLMLGHLLVHLKNDCHFEELPCVRPDCKEKVLRKDLRDHVEKACKYREATCSHCKSQVPMIALQVSLLQNE--SVEKNKSIQSLHNQI---CSFEIEIERQKEMLRNNESKIL----------------HLQRVIDSQAEKLKELDKEIRPFRQNWEEADSMKSSVESLQNRVTELESVDKSAGQVARNTGLLESQLSRHDQM--LSVHDIRLADMDLRFQVLETASYNGVLIWKIRDYKRRKQEAVMGKTLSLYSQPFYTGYFGYKMCARVYLNGDGMGKGTHLSLFFVIMRGEYDALLPWPFKQKVTLMLMDQGSSRRHLGDAFKPDPNSSSFKKPTGEMNIASGCPVFVAQTVLENGTYIKDDTIFIKVIV 477
BLAST of TNF receptor-associated factor vs. Ensembl Human
Match: TRAF2 (TNF receptor associated factor 2 [Source:HGNC Symbol;Acc:HGNC:12032]) HSP 1 Score: 150.599 bits (379), Expect = 3.919e-37 Identity = 123/493 (24.95%), Postives = 220/493 (44.62%), Query Frame = 2
Query: 1394 QIEARLRCGACTKLLKEPRQTECGCRLCTECIIELTLNGPKQCPDCKETEI----ASLGETQE---DRAASREIMNMRIKCPNKPCNWEGKIREASA---------------------------HL-NQCRYKRKPCEKCQQPISESEEKQHENVCEERRTRCEYCNITETWKQIQQEHVNVKEEKICDRFRGKCP-NKCGVEEEIE-----------LKEHWERCSRKRIEC-PM----AKWGCKIKILREETIQHVQETAEEHLKIWXXXXXXXXXXXXXXXXE--IESHKI--LMTEIFNTRESFELARIGMSETEKNVENEMKRLREHYQKLRSYTPTGENPPIAPYIWRIEEFTRKWQRARDGTEVSITSPPFYSWKNGYKLRMRVYPNGDGAGKDTHVSVFFVLVKGEWDELQSWPFSNKMAFTIM--SAKDAHVERLKPD-GAPCYNKPTADVGTAIGSPR---IMRQNVMWEYLEGDTLFVKWSV 2686
++EA+ C AC +L+ P Q +CG R C+ C+ + +GP+ C C I S+ E+ D AA RE+ ++ CP+ C W+G ++E + HL ++C + C C+ P ++ K H VC + C+ C + ++ Q+HV K C + R C + G E +E L+EH +E P+ + G ++ + R E+++ T E + + ++ + + ++ KI L +++ S L + M++ E+ V ++ + T G +IW+I +F RK Q A G +I SP FY+ + GYK+ +R+Y NGDG G+ TH+S+FFV++KG D L WPF+ K+ ++ + ++ ++ +PD + + +P D+ A G P + + Y+ D +F+K V
Sbjct: 27 KLEAKYLCSACRNVLRRPFQAQCGHRYCSFCLASILSSGPQNCAACVHEGIYEEGISILESSSAFPDNAARREVESLPAVCPSDGCTWKGTLKEYESCHEGRCPLMLTECPACKGLVRLGEKERHLEHECPERSLSCRHCRAPCCGADVKAHHEVCPKFPLTCDGCGKKKIPREKFQDHV-----KTCGKCRVPCRFHAIGCLETVEGEKQQEHEVQWLREHLAMLLSSVLEAKPLLGDQSHAGSEL-LQRCESLEKKTATFENIVCVLNREVERVAMTAEACSRQHRLDQDKIEALSSKVQQLERSIGLKDLAMADLEQKV-----------LEMEASTYDGV------FIWKISDFARKRQEAVAGRIPAIFSPAFYTSRYGYKMCLRIYLNGDGTGRGTHLSLFFVVMKGPNDALLRWPFNQKVTLMLLDQNNREHVIDAFRPDVTSSSFQRPVNDMNIASGCPLFCPVSKMEAKNSYVRDDAIFIKAIV 496
BLAST of TNF receptor-associated factor vs. Ensembl Human
Match: TRAF3 (TNF receptor associated factor 3 [Source:HGNC Symbol;Acc:HGNC:12033]) HSP 1 Score: 143.665 bits (361), Expect = 1.815e-34 Identity = 124/511 (24.27%), Postives = 224/511 (43.84%), Query Frame = 2
Query: 1397 IEARLRCGACTKLLKEPRQTECGCRLCTECIIELTLNGPKQCPDCKETEIASLGETQEDRAASREIMNMRIKCPN--KPCNWEGKIREASAHL-NQCRYKRKPCEK--CQQPISESEEKQH-ENVCEERRTRCEYCNITETWKQIQQEHVNVKEEKICDRFRGKCPNKCGVEEEI-------ELKEHWERCSRKRIECPMAKWGC----KIKILREETIQHVQETAEEHLKIWXXXXXXXXXXXXXXXXEIESHKILMTEIFNTRESFELARIGMSETE--KNVENEMKRLREHYQKLRSYTPTGE---------------------------------NPPIAPYIWRIEEFTRKWQ-------------RARD----------GTEVSITSPPFYSWKNGYKLRMRVYPNGDGAGKDTHVSVFFVLVKGEWDELQSWPFSNKMAFTIM---SAKDAHVERLKPD-GAPCYNKPTADVGTAIGSPRIMRQNVM--WEYLEGDTLFVKWSV 2686
+E + +C C +L P+QTECG R C C+ L + +C C+E+ + + +D REI+ ++I C N + C + + HL N C ++ PC + C++ + + + H E C+ R C +C Q+ + E+ C CP+KC V+ + ++K H + + + + +W K+ +L+ E+++ + H +I +IEIE K ++ N + L R+ S+ E K ++ E++ R+++++ S + E + ++ + R+ + ++Q + RD G +S+ S PFY+ GYK+ RVY NGDG GK TH+S+FFV+++GE+D L WPF K+ +M S++ + KPD + + KPT ++ A G P + Q V+ Y++ DT+F+K V
Sbjct: 47 VEDKYKCEKCHLVLCSPKQTECGHRFCESCMAALLSSSSPKCTACQESIVKD--KVFKDNCCKREILALQIYCRNESRGCAEQLMLGHLLVHLKNDCHFEELPCVRPDCKEKVLRKDLRDHVEKACKYREATCSHCK-----SQVPMIALQKHEDTDCPCVVVSCPHKCSVQTLLRSEGTNQQIKAHEASSAVQHVNL-LKEWSNSLEKKVSLLQNESVEKNKSIQSLHNQIC------------SFEIEIERQKEMLRN--NESKILHLQRVIDSQAEKLKELDKEIRPFRQNWEEADSMKSSVESLQNRVTELESVDKSAGQVARNTGLLESQLSRHDQMLSVHDIRLADMDLRFQVLETASYNGVLIWKIRDYKRRKQEAVMGKTLSLYSQPFYTGYFGYKMCARVYLNGDGMGKGTHLSLFFVIMRGEYDALLPWPFKQKVTLMLMDQGSSRRHLGDAFKPDPNSSSFKKPTGEMNIASGCPVFVAQTVLENGTYIKDDTIFIKVIV 535
BLAST of TNF receptor-associated factor vs. Ensembl Human
Match: TRAF3 (TNF receptor associated factor 3 [Source:HGNC Symbol;Acc:HGNC:12033]) HSP 1 Score: 143.665 bits (361), Expect = 1.815e-34 Identity = 124/511 (24.27%), Postives = 224/511 (43.84%), Query Frame = 2
Query: 1397 IEARLRCGACTKLLKEPRQTECGCRLCTECIIELTLNGPKQCPDCKETEIASLGETQEDRAASREIMNMRIKCPN--KPCNWEGKIREASAHL-NQCRYKRKPCEK--CQQPISESEEKQH-ENVCEERRTRCEYCNITETWKQIQQEHVNVKEEKICDRFRGKCPNKCGVEEEI-------ELKEHWERCSRKRIECPMAKWGC----KIKILREETIQHVQETAEEHLKIWXXXXXXXXXXXXXXXXEIESHKILMTEIFNTRESFELARIGMSETE--KNVENEMKRLREHYQKLRSYTPTGE---------------------------------NPPIAPYIWRIEEFTRKWQ-------------RARD----------GTEVSITSPPFYSWKNGYKLRMRVYPNGDGAGKDTHVSVFFVLVKGEWDELQSWPFSNKMAFTIM---SAKDAHVERLKPD-GAPCYNKPTADVGTAIGSPRIMRQNVM--WEYLEGDTLFVKWSV 2686
+E + +C C +L P+QTECG R C C+ L + +C C+E+ + + +D REI+ ++I C N + C + + HL N C ++ PC + C++ + + + H E C+ R C +C Q+ + E+ C CP+KC V+ + ++K H + + + + +W K+ +L+ E+++ + H +I +IEIE K ++ N + L R+ S+ E K ++ E++ R+++++ S + E + ++ + R+ + ++Q + RD G +S+ S PFY+ GYK+ RVY NGDG GK TH+S+FFV+++GE+D L WPF K+ +M S++ + KPD + + KPT ++ A G P + Q V+ Y++ DT+F+K V
Sbjct: 47 VEDKYKCEKCHLVLCSPKQTECGHRFCESCMAALLSSSSPKCTACQESIVKD--KVFKDNCCKREILALQIYCRNESRGCAEQLMLGHLLVHLKNDCHFEELPCVRPDCKEKVLRKDLRDHVEKACKYREATCSHCK-----SQVPMIALQKHEDTDCPCVVVSCPHKCSVQTLLRSEGTNQQIKAHEASSAVQHVNL-LKEWSNSLEKKVSLLQNESVEKNKSIQSLHNQIC------------SFEIEIERQKEMLRN--NESKILHLQRVIDSQAEKLKELDKEIRPFRQNWEEADSMKSSVESLQNRVTELESVDKSAGQVARNTGLLESQLSRHDQMLSVHDIRLADMDLRFQVLETASYNGVLIWKIRDYKRRKQEAVMGKTLSLYSQPFYTGYFGYKMCARVYLNGDGMGKGTHLSLFFVIMRGEYDALLPWPFKQKVTLMLMDQGSSRRHLGDAFKPDPNSSSFKKPTGEMNIASGCPVFVAQTVLENGTYIKDDTIFIKVIV 535
BLAST of TNF receptor-associated factor vs. Ensembl Human
Match: TRAF5 (TNF receptor associated factor 5 [Source:HGNC Symbol;Acc:HGNC:12035]) HSP 1 Score: 133.65 bits (335), Expect = 3.460e-31 Identity = 119/518 (22.97%), Postives = 223/518 (43.05%), Query Frame = 2
Query: 1394 QIEARLRCGACTKLLKEPRQTECGCRLCTECIIEL-TLNGPKQCPDCKETEIASLGETQEDRAASREIMNMRI-----------------------------KCPNKPCNWEGKIREASAHLN-QCRYKRKPC----------------------------EKCQQPISESEEKQHENVCEERRTRCEY----CNITETWKQIQQ-------EHV------NVK-EEKICDRFRGKCPNKCGVEEEIELKEHWERCSRKRIECPMAKWGC---KIKILREETIQHVQETAEEHLKIWXXXXXXXXXXXXXXXXEIESHKILMTEIFNTRESFELARIGMSETEKNVENEMKRLREHYQKLRSYTPTGENPPIAPYIWRIEEFTRKWQRARDGTEVSITSPPFYSWKNGYKLRMRVYPNGDGAGKDTHVSVFFVLVKGEWDELQSWPFSNKMAFTIM--SAKDAHVERLKPD-GAPCYNKPTADVGTAIGSPRIMRQNVMWE----YLEGDTLFVKWSV 2686
++E R +C C +L P QT CG R C CI+ L LN CP + E+ E +D RE++N+ + +C N+ C ++ HL+ C+++++ C C + I ++E +H VC E C + C +T+ + +QQ EH+ NV+ EE+I D + + +++ E + E+ K+ K G I++ + A+ H + M + + + +++ K +T + N + + ++ + ++ +L ++ ++ + T N + IW++ ++ K + A DG VSI S FY+ + GY+L R Y NGDG+G+ +H+S++FV+++GE+D L WPF ++ ++ S K +E KPD + + +P ++ A G PR + +V+ Y++ DTLF+K +V
Sbjct: 38 RLEERYKCAFCHSVLHNPHQTGCGHRFCQHCILSLRELNTVPICP--VDKEVIKSQEVFKDNCCKREVLNLYVYCSNAPGCNAKVILGRYQDHLQQCLFQPVQCSNEKCREPVLRKDLKEHLSASCQFRKEKCLYCKKDVVVINLQNHEENLCPEYPVFCPNNCAKIILKTEVDEHLAVCPEAEQDCPFKHYGCAVTDKRRNLQQHEHSALREHMRLVLEKNVQLEEQISDLHKSLEQKESKIQQLAETIKKLEK-EFKQFAQLFGKNGSFLPNIQVFASHIDKSAWLEAQVHQLLQMVNQQQNKFDLRPLMEAVDTVKQKITLLENNDQRLAVLEEETNKHDTHINIHKAQLSKNEERFKLLEGTCYNGKL---IWKVTDYKMKKREAVDGHTVSIFSQSFYTSRCGYRLCARAYLNGDGSGRGSHLSLYFVVMRGEFDSLLQWPFRQRVTLMLLDQSGKKNIMETFKPDPNSSSFKRPDGEMNIASGCPRFVAHSVLENAKNAYIKDDTLFLKVAV 549
BLAST of TNF receptor-associated factor vs. Ensembl Celegans
Match: trf-1 (TNF Receptor Associated Factor (TRAF) homolog; TRF-1 [Source:UniProtKB/TrEMBL;Acc:G5EG80]) HSP 1 Score: 129.798 bits (325), Expect = 7.610e-31 Identity = 98/446 (21.97%), Postives = 182/446 (40.81%), Query Frame = 2
Query: 1397 IEARLRCGACTKLLKEPRQTECGCRLCTECIIELTLNGPKQCPDCKETEIASLGET-QEDRAASREIMNMRIKCP--NKPCNWEGKIREASAHLNQCRYKRK-PCEKCQQPISESEEKQHENVCEERRTRCEYCNITETWKQIQQEHVNVKEEKICDRFRGKCPNKCGVEEE--IELKEHWERCSRKRIECPMAKWGCKIKILREETIQHVQETAEEHLKIWXXXXXXXXXXXXXXXXEIESHKILMTEIFNTRESFELARIGMSETEKNVENEMKRLREHYQKLRSYTPTGENPPIAPYIWRIEEFTRKWQRARDGTEVSITSPPFYSWKNGYKLRMRVYPNGDGAGKDTHVSVFFVLVKGEWDELQSWPFSNKMAFTIMSAKDAHVERLK----------PDGAPCYNKPTADVGTAIGSPRIMRQNVMWEYLEGDTLFVKWSV 2686
+ A C C + L++P + C C +C + P C + E Q DRA ++I+ + + C + C W+G++ HL++C +K CEKC + ++++ ++H CE R C +CN +T + +E + K C + CP +CG+ + +E++ H C CP +GC +E QH+ + HL L EI + + ++EL +E +M + ++ S T IW+I++ ++ A+ G + +I S PF S + GYK+ GDG+ +S++ +L+KGE+D WPF + +++ +R+ +P + A GS ++ Y++ D ++V+ V
Sbjct: 12 LPADCTCPICEQALRDPIKLNCDHHYCRQC-----FENENRTPGCAACQTIIQPELCQHDRAKQKQILALPVVCTFESSGCPWDGQLGTLHDHLSECTFKSSLKCEKCGRQFAKNDLEKHRAKCELNRAVCSFCN--KTIRDSDRE----RHPKTCPQVIISCPFQCGLTDRPRLEIEAHCPSCPNVDNVCPFVPYGCTFAGGKESIQQHLSDEPVRHLMY------------------------LCDEITDLKGTYEL-----------MERDMGSFNDRQTRILSAAETCTEMFGPQLIWKIDKLQQRTNEAKSGADTTIFSVPFMSHRFGYKMMACACLFGDGSSAGKSISLYVLLLKGEFDPTLEWPFHRAIKISLLDQNPRPEDRVNITYVIDPRKLKANEKFLARPRGERNAAFGSQSFCSLAILQNYVKDDKIYVQIDV 411
BLAST of TNF receptor-associated factor vs. Ensembl Celegans
Match: rpl-35 (60S ribosomal protein L35 [Source:UniProtKB/Swiss-Prot;Acc:P34662]) HSP 1 Score: 92.8189 bits (229), Expect = 1.696e-21 Identity = 51/107 (47.66%), Postives = 75/107 (70.09%), Query Frame = 2
Query: 80 MVKLRASELTKKNKADLEKQLHQLKTELAELRVAKVTGAGGTKLGKIRVLRKSIARVMTVMHTKQKDSLRQYYQHRKLKPQGIRTKATRAMRRQLTDNQKNKKTVRQ 400
M KL+ L + K L+K+L + KTELA LRV+KVTG +KL KIRV+RK+IAR++TV++ QK LR++Y K KP +R K TRA+RR+LT ++ + ++ +Q
Sbjct: 1 MTKLKCKSLRGEKKDALQKKLDEQKTELATLRVSKVTGGAASKLSKIRVVRKNIARLLTVINQTQKQELRKFYADHKYKPIDLRLKKTRAIRRRLTAHELSLRSAKQ 107
BLAST of TNF receptor-associated factor vs. Ensembl Celegans
Match: rpl-35 (60S ribosomal protein L35 [Source:UniProtKB/Swiss-Prot;Acc:P34662]) HSP 1 Score: 92.8189 bits (229), Expect = 1.696e-21 Identity = 51/107 (47.66%), Postives = 75/107 (70.09%), Query Frame = 2
Query: 80 MVKLRASELTKKNKADLEKQLHQLKTELAELRVAKVTGAGGTKLGKIRVLRKSIARVMTVMHTKQKDSLRQYYQHRKLKPQGIRTKATRAMRRQLTDNQKNKKTVRQ 400
M KL+ L + K L+K+L + KTELA LRV+KVTG +KL KIRV+RK+IAR++TV++ QK LR++Y K KP +R K TRA+RR+LT ++ + ++ +Q
Sbjct: 1 MTKLKCKSLRGEKKDALQKKLDEQKTELATLRVSKVTGGAASKLSKIRVVRKNIARLLTVINQTQKQELRKFYADHKYKPIDLRLKKTRAIRRRLTAHELSLRSAKQ 107
BLAST of TNF receptor-associated factor vs. Ensembl Celegans
Match: rpl-35 (60S ribosomal protein L35 [Source:UniProtKB/Swiss-Prot;Acc:P34662]) HSP 1 Score: 92.8189 bits (229), Expect = 1.696e-21 Identity = 51/107 (47.66%), Postives = 75/107 (70.09%), Query Frame = 2
Query: 80 MVKLRASELTKKNKADLEKQLHQLKTELAELRVAKVTGAGGTKLGKIRVLRKSIARVMTVMHTKQKDSLRQYYQHRKLKPQGIRTKATRAMRRQLTDNQKNKKTVRQ 400
M KL+ L + K L+K+L + KTELA LRV+KVTG +KL KIRV+RK+IAR++TV++ QK LR++Y K KP +R K TRA+RR+LT ++ + ++ +Q
Sbjct: 1 MTKLKCKSLRGEKKDALQKKLDEQKTELATLRVSKVTGGAASKLSKIRVVRKNIARLLTVINQTQKQELRKFYADHKYKPIDLRLKKTRAIRRRLTAHELSLRSAKQ 107
BLAST of TNF receptor-associated factor vs. Ensembl Celegans
Match: trf-2 (TNF Receptor Associated Factor (TRAF) homolog [Source:UniProtKB/TrEMBL;Acc:Q9N586]) HSP 1 Score: 63.5438 bits (153), Expect = 9.849e-10 Identity = 49/195 (25.13%), Postives = 81/195 (41.54%), Query Frame = 2
Query: 1943 IECPMAKWGCKIKILREETIQHVQETAEEHLKIWXXXXXXXXXXXXXXXXEIESHKILMTEIFNTRESFELARIGMSETEKNVENEMKRLREHYQKLRSYTPTGENPPIAPYIWRIEEFTRKWQRA-RDGTEVSITSPPFYSWKNGYKLRMRVYPNGDGAGKDTHVSVFFVLVKGEWDELQSWPFSNKMAFTIMS 2524
I+CP + GC K E +HV++ HL + +S + T+I + ++ +GM + E+ ++ + +RI + +A ++ + SI S PFYS GYK+ P GDG + SVF L+KGEWD++ WPF + F+I+S
Sbjct: 84 IDCPFKEHGCHKKGENSEVKRHVRDDRNLHLVLL-----------------CQSLNPIRTKINIQQSAYVDKYVGMLQYMSIAESAFEKYGSQHT------------------FRIPKIGLTVVKATKNKSHRSIYSQPFYSHGYGYKMMAVAAPYGDGLAFREYFSVFVCLMKGEWDDILEWPFRCDVTFSILS 243
BLAST of TNF receptor-associated factor vs. Ensembl Fly
Match: RpL35 (gene:FBgn0029785 transcript:FBtr0070801) HSP 1 Score: 119.783 bits (299), Expect = 8.221e-31 Identity = 62/122 (50.82%), Postives = 89/122 (72.95%), Query Frame = 2
Query: 80 MVKLRASELTKKNKADLEKQLHQLKTELAELRVAKVTGAGGTKLGKIRVLRKSIARVMTVMHTKQKDSLRQYYQHRKLKPQGIRTKATRAMRRQLTDNQKNKKTVRQIRLDRAWPEIIYAIK 445
MVK++ SEL K+K +L KQL +LK EL LRVAKVTG +KL KIRV+RK+IARV VMH KQK++LR+ ++++K KP +R K TRA+R+ L+ N+KT+++IR +P+ +A+K
Sbjct: 1 MVKVKCSELRIKDKKELTKQLDELKNELLSLRVAKVTGGAPSKLSKIRVVRKAIARVYIVMHQKQKENLRKVFKNKKYKPLDLRKKKTRAIRKALSPRDANRKTLKEIRKRSVFPQRKFAVK 122
BLAST of TNF receptor-associated factor vs. Ensembl Fly
Match: RpL35 (gene:FBgn0029785 transcript:FBtr0345788) HSP 1 Score: 119.783 bits (299), Expect = 8.221e-31 Identity = 62/122 (50.82%), Postives = 89/122 (72.95%), Query Frame = 2
Query: 80 MVKLRASELTKKNKADLEKQLHQLKTELAELRVAKVTGAGGTKLGKIRVLRKSIARVMTVMHTKQKDSLRQYYQHRKLKPQGIRTKATRAMRRQLTDNQKNKKTVRQIRLDRAWPEIIYAIK 445
MVK++ SEL K+K +L KQL +LK EL LRVAKVTG +KL KIRV+RK+IARV VMH KQK++LR+ ++++K KP +R K TRA+R+ L+ N+KT+++IR +P+ +A+K
Sbjct: 1 MVKVKCSELRIKDKKELTKQLDELKNELLSLRVAKVTGGAPSKLSKIRVVRKAIARVYIVMHQKQKENLRKVFKNKKYKPLDLRKKKTRAIRKALSPRDANRKTLKEIRKRSVFPQRKFAVK 122
BLAST of TNF receptor-associated factor vs. Ensembl Fly
Match: RpL35 (gene:FBgn0029785 transcript:FBtr0070800) HSP 1 Score: 119.783 bits (299), Expect = 8.221e-31 Identity = 62/122 (50.82%), Postives = 89/122 (72.95%), Query Frame = 2
Query: 80 MVKLRASELTKKNKADLEKQLHQLKTELAELRVAKVTGAGGTKLGKIRVLRKSIARVMTVMHTKQKDSLRQYYQHRKLKPQGIRTKATRAMRRQLTDNQKNKKTVRQIRLDRAWPEIIYAIK 445
MVK++ SEL K+K +L KQL +LK EL LRVAKVTG +KL KIRV+RK+IARV VMH KQK++LR+ ++++K KP +R K TRA+R+ L+ N+KT+++IR +P+ +A+K
Sbjct: 1 MVKVKCSELRIKDKKELTKQLDELKNELLSLRVAKVTGGAPSKLSKIRVVRKAIARVYIVMHQKQKENLRKVFKNKKYKPLDLRKKKTRAIRKALSPRDANRKTLKEIRKRSVFPQRKFAVK 122
BLAST of TNF receptor-associated factor vs. Ensembl Fly
Match: Traf4 (gene:FBgn0026319 transcript:FBtr0334401) HSP 1 Score: 115.161 bits (287), Expect = 9.369e-26 Identity = 96/432 (22.22%), Postives = 166/432 (38.43%), Query Frame = 2
Query: 1586 REIMNMRIKCPN--KPCNWEGKIREASAHLNQCRYKRKPC-EKCQQPISESEEKQH-ENVCEERRTRCEYCNITETWKQIQQEHVNVKEEKI------------------------------------------------CDRFRGKCPNKC--GVEEEIELKEHW-ERCSRKRIECPMAKWGCKIKILREETIQHVQETAEEHLKIWXXXXXXXXXXXXXXXXEIESHKILMTEIFNTRESFELARIGMSETEKNVENEMKRLREHYQKLR-SYTPTGENPPIAPYIWRIEEFTRKWQRARDGTEVSITSPPFYSWKNGYKLRMRVYPNGDGAGKDTHVSVFFVLVKGEWDELQSWPFSNKMAFTIM-----SAKDAHVERLKPDGA-PCYNKPTADVG-TAIGSPRIMRQNVMWE--YLEGDTLFVKWSV 2686
+ IM + C + + C W ++R+ HLN C++ C KC I H + C RRTRCE+C + +++ + + +E + C R CP +C G EL+ H + C + C + GC+ K R+ H++ A HL + M +++ L+ KL +YT T +W+I +++ K AR + + SPPFY+ + GYKL+ ++ NG+G G++THVSV+ ++ GE+D L WPFS+ + FT+ S + E PD + +P+ + G PR + ++ +++GDT+F++ V
Sbjct: 88 KHIMGSLVFCIHHKQGCKWSDELRKLKGHLNACKHDATQCPNKCGAQIPRIMMTDHLQYTCTMRRTRCEFCQSEFSGAGLEEHNGSCGQEPVYCEAKCGQRILRGRMTLHKSKDCAKRLRRCAHCQREFSADTLPLHAAQCPRAPLACPQRCDAGPIPRGELEAHLRDECQSLAVSCSFKEAGCRFKGPRQMLEAHLESNAAAHLSL------------------------------------------MVALSSRQGQQIQMLKSAVSKLSINYTGT--------LLWKITDWSAKMAEARGKDGLELVSPPFYTSQYGYKLQASMFLNGNGPGENTHVSVYIKVLPGEYDALLKWPFSHSITFTLFEQGAQSGQGGVAESFVPDPTWENFQRPSNEPDQLGFGFPRFISHELLHSRPFIKGDTVFLRVKV 469
BLAST of TNF receptor-associated factor vs. Ensembl Fly
Match: Traf4 (gene:FBgn0026319 transcript:FBtr0077429) HSP 1 Score: 104.76 bits (260), Expect = 2.517e-22 Identity = 84/345 (24.35%), Postives = 145/345 (42.03%), Query Frame = 2
Query: 1697 CE-KCQQPISESEEKQHENV-CEERRTRCEYCNITETWKQIQQEHVNVKEEKICDRFRGKCPNKC--GVEEEIELKEHW-ERCSRKRIECPMAKWGCKIKILREETIQHVQETAEEHLKIWXXXXXXXXXXXXXXXXEIESHKILMTEIFNTRESFELARIGMSETEKNVENEMKRLREHYQKLR-SYTPTGENPPIAPYIWRIEEFTRKWQRARDGTEVSITSPPFYSWKNGYKLRMRVYPNGDGAGKDTHVSVFFVLVKGEWDELQSWPFSNKMAFTIM-----SAKDAHVERLKPDGA-PCYNKPTADVG-TAIGSPRIMRQNVMWE--YLEGDTLFVKWSV 2686
CE KC Q I H++ C +R RC +C ++ + + + + C R CP +C G EL+ H + C + C + GC+ K R+ H++ A HL + M +++ L+ KL +YT T +W+I +++ K AR + + SPPFY+ + GYKL+ ++ NG+G G++THVSV+ ++ GE+D L WPFS+ + FT+ S + E PD + +P+ + G PR + ++ +++GDT+F++ V
Sbjct: 190 CEAKCGQRILRGRMTLHKSKDCAKRLRRCAHCQ-----REFSADTLPLHAAQ-CPRAPLACPQRCDAGPIPRGELEAHLRDECQSLAVSCSFKEAGCRFKGPRQMLEAHLESNAAAHLSL------------------------------------------MVALSSRQGQQIQMLKSAVSKLSINYTGT--------LLWKITDWSAKMAEARGKDGLELVSPPFYTSQYGYKLQASMFLNGNGPGENTHVSVYIKVLPGEYDALLKWPFSHSITFTLFEQGAQSGQGGVAESFVPDPTWENFQRPSNEPDQLGFGFPRFISHELLHSRPFIKGDTVFLRVKV 478
BLAST of TNF receptor-associated factor vs. Ensembl Zebrafish
Match: traf4a (tnf receptor-associated factor 4a [Source:ZFIN;Acc:ZDB-GENE-040308-1]) HSP 1 Score: 139.428 bits (350), Expect = 8.231e-34 Identity = 111/501 (22.16%), Postives = 206/501 (41.12%), Query Frame = 2
Query: 1406 RLRCGACTKLLKEPRQ-TECGCRLCTECIIELTLNGPKQCPDCKETEIASLGETQEDRAASREIMNMRIKCPN--KPCNWEGKIREASAHLNQCRYKRKPC-EKCQQPISESEEKQH-ENVCEERRTRCEYCNITETWKQIQQEHVNVKEEKI------------------------------------------------CDRFRGKCPNKCGVEEEI--ELKEHW-ERCSRKRIECPMAKWGCKIKILREETIQHVQETAEEHLKIWXXXXXXXXXXXXXXXXEIESHKILMTEIFNTR--ESFELARIGMSETEKNVENEMKRLREHYQKLRSYTPTGENPPIAPYIWRIEEFTRKWQRARDGTEVSITSPPFYSWKNGYKLRMRVYPNGDGAGKDTHVSVFFVLVKGEWDELQSWPFSNKMAFTIMSAKDAHV-------ERLKPDG------APCYNKPTADVGT-AIGSPRIMRQNVMWE--YLEGDTLFVKWSV 2686
R +C C+K ++EP Q + CG R C C+ E G +CP+ + + D ++I+ + I+C + + C W G++++ +H + C + PC +C ++ + +H ++ C +R+ +CE+C T + + +E + C RF +CPN+CG +L H E C + CP + GCK + + +H++E+ + HL +M + + E EL R EM+ L + + IW++ +++RK Q A+ SPPFY+ + GYKL++ + NG+G+G+ +H+S++ ++ GE+D L WPFS K+ F+I+ D + E PD PC ++ + D T G P+ + + + Y+ +++F+K S+
Sbjct: 15 RFQCPLCSKAMREPVQVSTCGHRFCDTCLQEFLSEGVFKCPE--DQLPLDYAKIYPDPELEQQILALPIRCIHSEEGCRWTGQMKQLQSHFSTCAFNVIPCPNRCSVKLTRRDLPEHLQHDCPKRKVKCEFCGSEFTGEAYENHQGICPQESVYCENKCGARMMRRLLSQHTMTECPKRTQPCKYCGKEFVYDTIQNHQYHCPRFPVQCPNQCGTPNIAREDLANHVKESCGSALVLCPFKEAGCKHRCPKMAIGRHLEESTKSHL-------------------------TMMCSLVGRQRQEILELRR------------EMEELSVSHDGV--------------LIWKLTDYSRKLQEAKLRNNHEFFSPPFYTHRYGYKLQVSAFLNGNGSGEGSHLSIYIRVLPGEYDNLLEWPFSYKVTFSILDQSDPSLSKPQHITETFNPDPNWKNFQKPCSSRNSLDESTLGFGYPKFISHEEIKKRNYIRDNSIFLKASI 462
BLAST of TNF receptor-associated factor vs. Ensembl Zebrafish
Match: traf4a (tnf receptor-associated factor 4a [Source:ZFIN;Acc:ZDB-GENE-040308-1]) HSP 1 Score: 139.428 bits (350), Expect = 8.231e-34 Identity = 111/501 (22.16%), Postives = 206/501 (41.12%), Query Frame = 2
Query: 1406 RLRCGACTKLLKEPRQ-TECGCRLCTECIIELTLNGPKQCPDCKETEIASLGETQEDRAASREIMNMRIKCPN--KPCNWEGKIREASAHLNQCRYKRKPC-EKCQQPISESEEKQH-ENVCEERRTRCEYCNITETWKQIQQEHVNVKEEKI------------------------------------------------CDRFRGKCPNKCGVEEEI--ELKEHW-ERCSRKRIECPMAKWGCKIKILREETIQHVQETAEEHLKIWXXXXXXXXXXXXXXXXEIESHKILMTEIFNTR--ESFELARIGMSETEKNVENEMKRLREHYQKLRSYTPTGENPPIAPYIWRIEEFTRKWQRARDGTEVSITSPPFYSWKNGYKLRMRVYPNGDGAGKDTHVSVFFVLVKGEWDELQSWPFSNKMAFTIMSAKDAHV-------ERLKPDG------APCYNKPTADVGT-AIGSPRIMRQNVMWE--YLEGDTLFVKWSV 2686
R +C C+K ++EP Q + CG R C C+ E G +CP+ + + D ++I+ + I+C + + C W G++++ +H + C + PC +C ++ + +H ++ C +R+ +CE+C T + + +E + C RF +CPN+CG +L H E C + CP + GCK + + +H++E+ + HL +M + + E EL R EM+ L + + IW++ +++RK Q A+ SPPFY+ + GYKL++ + NG+G+G+ +H+S++ ++ GE+D L WPFS K+ F+I+ D + E PD PC ++ + D T G P+ + + + Y+ +++F+K S+
Sbjct: 15 RFQCPLCSKAMREPVQVSTCGHRFCDTCLQEFLSEGVFKCPE--DQLPLDYAKIYPDPELEQQILALPIRCIHSEEGCRWTGQMKQLQSHFSTCAFNVIPCPNRCSVKLTRRDLPEHLQHDCPKRKVKCEFCGSEFTGEAYENHQGICPQESVYCENKCGARMMRRLLSQHTMTECPKRTQPCKYCGKEFVYDTIQNHQYHCPRFPVQCPNQCGTPNIAREDLANHVKESCGSALVLCPFKEAGCKHRCPKMAIGRHLEESTKSHL-------------------------TMMCSLVGRQRQEILELRR------------EMEELSVSHDGV--------------LIWKLTDYSRKLQEAKLRNNHEFFSPPFYTHRYGYKLQVSAFLNGNGSGEGSHLSIYIRVLPGEYDNLLEWPFSYKVTFSILDQSDPSLSKPQHITETFNPDPNWKNFQKPCSSRNSLDESTLGFGYPKFISHEEIKKRNYIRDNSIFLKASI 462
BLAST of TNF receptor-associated factor vs. Ensembl Zebrafish
Match: traf6 (TNF receptor-associated factor 6 [Source:NCBI gene;Acc:554561]) HSP 1 Score: 132.109 bits (331), Expect = 7.617e-31 Identity = 112/438 (25.57%), Postives = 200/438 (45.66%), Query Frame = 2
Query: 1397 IEARLRCGACTKLLKEPRQTECGCRLCTECIIELTLNGPKQCPDCKETEIASLGETQEDRAASREIMNMRIKCPNKPCNWEGKIREASAHLNQCRYKRKPCEKCQQ--PISESEEKQHENVCEERRTRCEYCNITETWKQIQQEHVNVKEEKICDRFRGKCPNKCGVEE-EIELKEHWER-CSRKRIECPMAKWGCKIKILREETIQHVQETAEEHLKI---WXXXXXXXXXXXXXXXXEIESHKILMT-----------EIFNTRESF-----ELARIGM--------SETEKNVENEMKR----LREHYQKLRSYTPTGENPPIAPYIWRIEEFTRKWQRARDGTEVSITSPPFYSWKNGYKLRMRVYPNGDGAGK-DTHVSVFFVLVKGEWDELQSWPFSNKMAFTIMSAKDA--HVERL--KPDGAPCYNKPTA 2590
+E++ C C L+ QT CG R C CI + + ++CP + E+ + D A REI+++ +KC N C+ + ++R+ HL+QCR+ PC +CQ+ PIS +E + ++ C +R C C + + ++Q H E+ C F C +E +L H + C + + C + +GC+ K+ R E QH+QE + H++ ++ + + M + S + E+ N RE+ L R ++T+KN E++R L E ++L + G Y+WR+E F+ + G + + SPPFY+ + GYKL +R++ A + +S+F ++GE+D SWP + ++ + H+E + KPD + +PT
Sbjct: 65 LESKYECPICLMGLRSAVQTPCGHRFCDSCIRKSIRDTGQKCP--VDNEVLLEEQLFPDNFAKREILSLTVKCSNFGCSEKMELRQLEKHLSQCRFATAPCPQCQESVPISHLDEHKSQH-CLQRIMTCPDCAGSFVYA-VKQNH-----EQFCP-FANTVCEYCEMELIRDQLALHCDTDCLKAPVACTFSTFGCREKMTRNELAQHMQEFTQMHMRYMAEFLRSQTLNNCTMPSAAAHLSSDDRGASARSPDSCQCKQELLNLRETVLELEGRLVRQDQQIRELCIHNDTQKNQVTELRRKLVSLEESTRELEAQQYQG------IYVWRVENFSHHLRNQEAGQPIVLHSPPFYTGRPGYKLCLRLHLQTPSAPRCSNFISLFVHTMQGEFDSQLSWPLQGTIRLAVLDQVEGQHHIEVMETKPD-LQAFQRPTV 485
BLAST of TNF receptor-associated factor vs. Ensembl Zebrafish
Match: traf6 (TNF receptor-associated factor 6 [Source:NCBI gene;Acc:554561]) HSP 1 Score: 132.109 bits (331), Expect = 7.617e-31 Identity = 112/438 (25.57%), Postives = 200/438 (45.66%), Query Frame = 2
Query: 1397 IEARLRCGACTKLLKEPRQTECGCRLCTECIIELTLNGPKQCPDCKETEIASLGETQEDRAASREIMNMRIKCPNKPCNWEGKIREASAHLNQCRYKRKPCEKCQQ--PISESEEKQHENVCEERRTRCEYCNITETWKQIQQEHVNVKEEKICDRFRGKCPNKCGVEE-EIELKEHWER-CSRKRIECPMAKWGCKIKILREETIQHVQETAEEHLKI---WXXXXXXXXXXXXXXXXEIESHKILMT-----------EIFNTRESF-----ELARIGM--------SETEKNVENEMKR----LREHYQKLRSYTPTGENPPIAPYIWRIEEFTRKWQRARDGTEVSITSPPFYSWKNGYKLRMRVYPNGDGAGK-DTHVSVFFVLVKGEWDELQSWPFSNKMAFTIMSAKDA--HVERL--KPDGAPCYNKPTA 2590
+E++ C C L+ QT CG R C CI + + ++CP + E+ + D A REI+++ +KC N C+ + ++R+ HL+QCR+ PC +CQ+ PIS +E + ++ C +R C C + + ++Q H E+ C F C +E +L H + C + + C + +GC+ K+ R E QH+QE + H++ ++ + + M + S + E+ N RE+ L R ++T+KN E++R L E ++L + G Y+WR+E F+ + G + + SPPFY+ + GYKL +R++ A + +S+F ++GE+D SWP + ++ + H+E + KPD + +PT
Sbjct: 65 LESKYECPICLMGLRSAVQTPCGHRFCDSCIRKSIRDTGQKCP--VDNEVLLEEQLFPDNFAKREILSLTVKCSNFGCSEKMELRQLEKHLSQCRFATAPCPQCQESVPISHLDEHKSQH-CLQRIMTCPDCAGSFVYA-VKQNH-----EQFCP-FANTVCEYCEMELIRDQLALHCDTDCLKAPVACTFSTFGCREKMTRNELAQHMQEFTQMHMRYMAEFLRSQTLNNCTMPSAAAHLSSDDRGASARSPDSCQCKQELLNLRETVLELEGRLVRQDQQIRELCIHNDTQKNQVTELRRKLVSLEESTRELEAQQYQG------IYVWRVENFSHHLRNQEAGQPIVLHSPPFYTGRPGYKLCLRLHLQTPSAPRCSNFISLFVHTMQGEFDSQLSWPLQGTIRLAVLDQVEGQHHIEVMETKPD-LQAFQRPTV 485
BLAST of TNF receptor-associated factor vs. Ensembl Zebrafish
Match: traf6 (TNF receptor-associated factor 6 [Source:NCBI gene;Acc:554561]) HSP 1 Score: 132.109 bits (331), Expect = 7.617e-31 Identity = 112/438 (25.57%), Postives = 200/438 (45.66%), Query Frame = 2
Query: 1397 IEARLRCGACTKLLKEPRQTECGCRLCTECIIELTLNGPKQCPDCKETEIASLGETQEDRAASREIMNMRIKCPNKPCNWEGKIREASAHLNQCRYKRKPCEKCQQ--PISESEEKQHENVCEERRTRCEYCNITETWKQIQQEHVNVKEEKICDRFRGKCPNKCGVEE-EIELKEHWER-CSRKRIECPMAKWGCKIKILREETIQHVQETAEEHLKI---WXXXXXXXXXXXXXXXXEIESHKILMT-----------EIFNTRESF-----ELARIGM--------SETEKNVENEMKR----LREHYQKLRSYTPTGENPPIAPYIWRIEEFTRKWQRARDGTEVSITSPPFYSWKNGYKLRMRVYPNGDGAGK-DTHVSVFFVLVKGEWDELQSWPFSNKMAFTIMSAKDA--HVERL--KPDGAPCYNKPTA 2590
+E++ C C L+ QT CG R C CI + + ++CP + E+ + D A REI+++ +KC N C+ + ++R+ HL+QCR+ PC +CQ+ PIS +E + ++ C +R C C + + ++Q H E+ C F C +E +L H + C + + C + +GC+ K+ R E QH+QE + H++ ++ + + M + S + E+ N RE+ L R ++T+KN E++R L E ++L + G Y+WR+E F+ + G + + SPPFY+ + GYKL +R++ A + +S+F ++GE+D SWP + ++ + H+E + KPD + +PT
Sbjct: 65 LESKYECPICLMGLRSAVQTPCGHRFCDSCIRKSIRDTGQKCP--VDNEVLLEEQLFPDNFAKREILSLTVKCSNFGCSEKMELRQLEKHLSQCRFATAPCPQCQESVPISHLDEHKSQH-CLQRIMTCPDCAGSFVYA-VKQNH-----EQFCP-FANTVCEYCEMELIRDQLALHCDTDCLKAPVACTFSTFGCREKMTRNELAQHMQEFTQMHMRYMAEFLRSQTLNNCTMPSAAAHLSSDDRGASARSPDSCQCKQELLNLRETVLELEGRLVRQDQQIRELCIHNDTQKNQVTELRRKLVSLEESTRELEAQQYQG------IYVWRVENFSHHLRNQEAGQPIVLHSPPFYTGRPGYKLCLRLHLQTPSAPRCSNFISLFVHTMQGEFDSQLSWPLQGTIRLAVLDQVEGQHHIEVMETKPD-LQAFQRPTV 485
BLAST of TNF receptor-associated factor vs. Ensembl Xenopus
Match: ssh2 (slingshot protein phosphatase 2 [Source:Xenbase;Acc:XB-GENE-993093]) HSP 1 Score: 149.058 bits (375), Expect = 2.592e-36 Identity = 129/496 (26.01%), Postives = 226/496 (45.56%), Query Frame = 2
Query: 1397 IEARLRCGACTKLLKEPRQTECGCRLCTECIIELTLNGPKQCPDCKETEIASLGETQEDRAASREIMNMRIKCPN--KPCNWEGKIREASAHL-NQCRYKRKPCEK--CQQPISESEEKQH-ENVCEERRTRCEYCNITETWKQIQQEHVNVKEEKICDRFRGKCPNKCGVEEEI-------ELKEHWERCSRKRIECPMAKWG----CKIKILREET--------IQHVQETA-----EEHLKIWXXXXXXXXXXXXXXXXEIESHKILMTEIFNTRESFELARIGMSETEKNVENEMKRLREHYQKLRSYTPTGENPPI--------------------------APY----IWRIEEFTRKWQRARDGTEVSITSPPFYSWKNGYKLRMRVYPNGDGAGKDTHVSVFFVLVKGEWDELQSWPFSNKMAFTIMSAKDA--HV-ERLKPD-GAPCYNKPTADVGTAIGSPRIMRQNVM--WEYLEGDTLFVKWSV 2686
+E + +C C +L PRQTECG R C C+ + + QC C++ + + +D RE++ +++ C N + C + HL + C+++ C + C++ + + H E C+ R T C++C ++Q+ E+ C CP+ C V+ + ++K H + + + M +W K+ +L+ E+ I H Q + E H + + + Q+ I+ + + K L EI N R++ + A GM ++++N + +L + S+ P I A Y IW+I ++ R+ Q A G +S+ S PFY+ GYK+ RVY NGDG GK TH+S+FFV+++GE+D L WPF K++ +M + H+ + KPD + + KPT ++ A G P + Q V+ Y++ DT+F+K V
Sbjct: 42 VEEKYKCEKCRLVLCNPRQTECGHRFCETCMNAILSSTSPQCMACEDN--ITKDKVFKDNCCRREVLALQMFCRNETRGCKELITLGNLLIHLKSDCQFEELSCPRADCKEKVIRKDLSDHIEKTCKYRETPCKFCRNQVPLVEMQKH-----EDVDCPSVVISCPHMCSVKSLLRSEGTNQQIKAHEASSAVQHVNL-MKEWSNYLEAKVSMLQNESSEKNKSIQILHNQMCSFEIEIERHKEQLRNNEARIIQLQRVIEGQADKLKDLDKEIRNLRQTGDEAD-GMKSNYESLQNRLSQLEVMAKNAASWNPGVLETQINRHDQMLSVHDIRLADMDLRFQVLETASYNGVLIWKIRDYKRRKQEAVMGKTLSLYSQPFYTGYFGYKMCARVYLNGDGMGKGTHLSLFFVIMRGEYDALLPWPFKQKVSLMLMDQGPSRRHLGDAFKPDPNSSSFKKPTGEMNIASGCPVFVAQTVLENGTYIKDDTIFIKVIV 528
BLAST of TNF receptor-associated factor vs. Ensembl Xenopus
Match: ssh2 (slingshot protein phosphatase 2 [Source:Xenbase;Acc:XB-GENE-993093]) HSP 1 Score: 145.976 bits (367), Expect = 3.397e-35 Identity = 135/520 (25.96%), Postives = 227/520 (43.65%), Query Frame = 2
Query: 1397 IEARLRCGACTKLLKEPRQTECGCRLCTECIIELTLNGPKQCPDCKETEIASLGETQEDRAASREIMNMRIKCPN--KPCNWEGKIREASAHL-NQCRYKRKPCEK--CQQPISESEEKQH-ENVCEERRTRCEYCNITETWKQIQQEHVNVKEEKICDRFRGKCPNKCGVEEEI--ELKEHW-------ERCSRKRIECP----------------------MAKWG----CKIKILREET--------IQHVQETA-----EEHLKIWXXXXXXXXXXXXXXXXEIESHKILMTEIFNTRESFELARIGMSETEKNVENEMKRLREHYQKLRSYTPTGENPPI--------------------------APY----IWRIEEFTRKWQRARDGTEVSITSPPFYSWKNGYKLRMRVYPNGDGAGKDTHVSVFFVLVKGEWDELQSWPFSNKMAFTIMSAKDA--HV-ERLKPD-GAPCYNKPTADVGTAIGSPRIMRQNVM--WEYLEGDTLFVKWSV 2686
+E + +C C +L PRQTECG R C C+ + + QC C++ + + +D RE++ +++ C N + C + HL + C+++ C + C++ + + H E C+ R T C++C ++Q+ E+ C CP+ C V+ + EL H CS KR C M +W K+ +L+ E+ I H Q + E H + + + Q+ I+ + + K L EI N R++ + A GM ++++N + +L + S+ P I A Y IW+I ++ R+ Q A G +S+ S PFY+ GYK+ RVY NGDG GK TH+S+FFV+++GE+D L WPF K++ +M + H+ + KPD + + KPT ++ A G P + Q V+ Y++ DT+F+K V
Sbjct: 42 VEEKYKCEKCRLVLCNPRQTECGHRFCETCMNAILSSTSPQCMACEDN--ITKDKVFKDNCCRREVLALQMFCRNETRGCKELITLGNLLIHLKSDCQFEELSCPRADCKEKVIRKDLSDHIEKTCKYRETPCKFCRNQVPLVEMQKH-----EDVDCPSVVISCPHMCSVKSLLRSELNAHLLECVNAPSTCSFKRYGCTFKGTNQQIKAHEASSAVQHVNLMKEWSNYLEAKVSMLQNESSEKNKSIQILHNQMCSFEIEIERHKEQLRNNEARIIQLQRVIEGQADKLKDLDKEIRNLRQTGDEAD-GMKSNYESLQNRLSQLEVMAKNAASWNPGVLETQINRHDQMLSVHDIRLADMDLRFQVLETASYNGVLIWKIRDYKRRKQEAVMGKTLSLYSQPFYTGYFGYKMCARVYLNGDGMGKGTHLSLFFVIMRGEYDALLPWPFKQKVSLMLMDQGPSRRHLGDAFKPDPNSSSFKKPTGEMNIASGCPVFVAQTVLENGTYIKDDTIFIKVIV 553
BLAST of TNF receptor-associated factor vs. Ensembl Xenopus
Match: sytl2 (synaptotagmin like 2 [Source:Xenbase;Acc:XB-GENE-945155]) HSP 1 Score: 139.813 bits (351), Expect = 9.049e-34 Identity = 112/503 (22.27%), Postives = 200/503 (39.76%), Query Frame = 2
Query: 1394 QIEARLRCGACTKLLKEPRQ-TECGCRLCTECIIELTLNGPKQCPDCKETEIASLGETQEDRAASREIMNMRIKCPN--KPCNWEGKIREASAHLNQCRYKRKPC-EKCQQPISESEEKQH-ENVCEERRTRCEYCNITETWKQIQQEHVNVKEEKI------------------------------------------------CDRFRGKCPNKCGVEEEI--ELKEHW-ERCSRKRIECPMAKWGCKIKILREETIQHVQETAEEHLKIWXXXXXXXXXXXXXXXXEIESHKILMTEIFNTRESFELARIGMSETEKNVENEMKRLREHYQKLRSYTPTGENPPIAPYIWRIEEFTRKWQRARDGTEVSITSPPFYSWKNGYKLRMRVYPNGDGAGKDTHVSVFFVLVKGEWDELQSWPFSNKMAFTIMSAKDAHV-------ERLKPDGA-PCYNKPTADVGT------AIGSPRIMRQNVMWE--YLEGDTLFVKWSV 2686
++ + C C K ++EP Q + CG R C C+ E G +CP+ + + DR ++M + I+C + + C W G++++ HLN C + PC +C + + +H ++ C +R+ RCE+C T + + +E + C R+ CPN+CG+ +L H + CS + CP GCK + + +H++E HL + MS E+ LR+ ++L S + G IW+I +++RK Q A+ SPPFY+ K GYKL++ + NG+G+G+ +++SV+ ++ GE+D L WPFS ++ F+++ D + E PD + KPT + G P+ + + + Y+ + +F++ SV
Sbjct: 11 KLRRKFLCPLCGKAMREPVQVSTCGHRFCDTCLQEFLSEGVFKCPE--DQLPLDYAKIYPDRDLETQVMGLSIRCIHSEEGCRWSGQLKQLQPHLNICAFNVIPCPNRCSTKLIRRDLPEHMQHDCPKRKVRCEFCGADFTGEAYEDHQGCCPQESVYCENKCGARMMRRVLSQHSLVECPKRTQPCPYCNKEFVFDTIQSHQYQCPRYPTPCPNQCGIASIAREDLSNHLKDSCSSALVLCPFKDSGCKHRGPKITISRHLEENMRAHLSM------------------------------------------MSSLVSRQRQEILELRKQVEEL-SVSSEGV------LIWKISDYSRKVQEAKVRGNFESFSPPFYTHKYGYKLQVSAFLNGNGSGEGSYLSVYIRVLPGEYDNLLEWPFSYRVTFSLLDQSDPSLSKPQHITETFNPDPNWKNFQKPTGSRNSLDESTLGFGYPKFISHEDIRKRNYVRDNAIFLRASV 462
BLAST of TNF receptor-associated factor vs. Ensembl Xenopus
Match: TRAF2 (TNF receptor associated factor 2 [Source:NCBI gene;Acc:100494415]) HSP 1 Score: 135.961 bits (341), Expect = 1.412e-32 Identity = 112/466 (24.03%), Postives = 193/466 (41.42%), Query Frame = 2
Query: 1394 QIEARLRCGACTKLLKEPRQTECGCRLCTECI------IELTLNGPKQCPDCKETEIASLGETQEDRAASREIMNMRIKCPNKPCNWEGKIREASAHLNQCRYKRKPCEKCQQPISESEEKQH-ENVCEERRTRCEYCNITETWKQIQQEHVNVKEEKICDRFRGKCPNKCGVEEEIELKEHWERCSRKRIECPMAKWGCKIKILREETIQHVQETAEEHLKIWXXXXXXXXXXXXXXXXEIESHKILMTEIFNTRESFELARIGMSETEKNVENEMKRLREHYQKLRSYTP-----TGENPPIAP-----------------YIWRIEEFTRKWQRARDGTEVSITSPPFYSWKNGYKLRMRVYPNGDGAGKDTHVSVFFVLVKGEWDELQSWPFSNKMAFTIM--SAKDAHVERLKPD-GAPCYNKPTADVGTAIGSP---RIMRQNVMWEYLEGDTLFVKWSV 2686
++E + C C LL+ P Q +CG R C+ C+ + G +CP E +W G + H +C Y PC C+ I + H E C ER+ C YC ++ + I+ ++IC +F C CG ++ K C + C A GC + ++ ++H ++ EHL + ++ + + +FE +S + VE E ++LR+ G+ I +IW+I EF +K Q A +G ++ SPPFY+ K GYK+ +R+Y NGDG G++TH+S+FFV++KG D L WPF+ K+ ++ + ++ ++ +PD + + +P +++ A G P ++ + Y+ DT+FVK V
Sbjct: 30 KLEVKYLCSDCKNLLRRPLQAQCGHRYCSHCLNKIIRWVARNWGGVPECPAVCERS-----------------------------DWTGALISV-GHEGKCPYLLAPCPACKTIIRAANRDLHSERECPERKLNCRYCKLSFYFPDIKAH------DEICPKFPMTCEG-CGRKKIPREKVRLFVC----MPCRYAAVGCTEMVENDKCLEHENKSLAEHLA--KGSPAPPANAPPNNSAKVAEMLLKFDTLDKKNTTFENI---VSVLNREVERSSHAAEELARQLRAADTRLERTLGQKELIVAELETRMQESELSTYDGVFIWKISEFGKKRQDAINGRCPAMFSPPFYTNKYGYKMCLRIYLNGDGTGRNTHLSLFFVVMKGNNDALLRWPFNQKVTLMLLDQNNREHVIDAFRPDVSSSSFQRPISEMNIASGCPLFCQVSKLEGKNSYVRDDTIFVKVIV 449
BLAST of TNF receptor-associated factor vs. Ensembl Xenopus
Match: slc12a1 (solute carrier family 12 member 1 [Source:Xenbase;Acc:XB-GENE-479925]) HSP 1 Score: 129.028 bits (323), Expect = 8.204e-30 Identity = 124/514 (24.12%), Postives = 221/514 (43.00%), Query Frame = 2
Query: 1394 QIEARLRCGACTKLLKEPRQTECGCRLCTECIIELT-LNGPKQCPDCKETEIASLGETQEDRAASREIMNMRIKCPNKP-----------------CNWEGKI------------REASAHL-NQCRYKRKPCEKCQQPISESEEKQHENV------------CEERRTRCEY----CNITETWKQIQQEHVNVKEEK---ICDRFRGKCPNKCGVEEEIELKEHWERCSRKRI-----EC------------------PMAKWGCKIKILREETIQHVQETAEEHLKIWXXXXXXXXXXXXXXXXEIESHKILMTEIFNTRESFELARIGMSETEKNVENEMKRLREHYQKLRSYTPTGENPPIAPYIWRIEEFTRKWQRARDGTEVSITSPPFYSWKNGYKLRMRVYPNGDGAGKDTHVSVFFVLVKGEWDELQSWPFSNKMAFTIM--SAKDAHVE---RLKPDGAPCYNKPTADVGTAIGSPRIMRQNVMWE-----YLEGDTLFVKWSV 2686
Q++ R +C +C +L P QT CG R C +CI L L+ QCP + E E +D RE++N+ + C N P C +E + +E HL ++C+ +++ C C+Q +S + E ++ + C E +C + CN+ ++++ + + +R V + ++LKEH + + EC +A + K L E+ IQ V ++EH ++ + + + + Q +E++K I N F+ + +S N ++ + ++ R T N + IW+I ++ RK + A +G VSI S FY+ GY+L R Y NGDG+GK + +S++FV++KGE+D + WPF K+ ++ S K H+ R P+ + + +P +++ A G PR + Y++ DTLF+K V
Sbjct: 37 QLQDRYKCASCHLVLHNPHQTGCGHRFCEKCISNLIELSETPQCP--IDMENIKSHEIFKDNCCKREVLNLLVYCKNSPACDVKVMLGRYQEHLGQCLYEMTLCSNDGCHDQMIRKELKGHLESECKLRQEACIYCKQTMSFNHENNYKKIFFSFQLDKHLCECPEAELQCTFSNYGCNVMVKRGKVKEHEDTFLRDHMLYVLNRNMKLEEQVLSVLQNLDLKEHQIQQLSDTVKWCEKECHQFGQFTGSNGNSLSSTKTLASYIDKSMWLEEQVIQLV---SKEHSRLDLRPILDTLESTKQRLSTLEAYK---DRIDNLDGQFKKHDVLLS-------NHKMQMTSNEERFRLVEGTSYNGKL---IWKITDYERKKREAMEGRAVSIFSQHFYTSWCGYRLCARAYLNGDGSGKGSFLSLYFVVMKGEFDSILLWPFKQKVTLMLLDQSGKKNHITDVFRADPNSSS-FKRPDSEMNIASGCPRFASHAQLENPKNGCYIKDDTLFIKIVV 531
BLAST of TNF receptor-associated factor vs. Ensembl Mouse
Match: Traf2 (TNF receptor-associated factor 2 [Source:MGI Symbol;Acc:MGI:101835]) HSP 1 Score: 174.866 bits (442), Expect = 2.328e-45 Identity = 129/485 (26.60%), Postives = 223/485 (45.98%), Query Frame = 2
Query: 1394 QIEARLRCGACTKLLKEPRQTECGCRLCTECIIELTLNGPKQCPDC-----KETEIASLGETQE--DRAASREIMNMRIKCPNKPCNWEGKIREA-SAHLNQCRYKRKPCEKCQQPISESEEKQH-ENVCEERRTRCEYCNITETWKQIQQEHVNVK-EEKICDRFRGKCPNKCGVEEEI---ELKEHWERCSRKRIECPMAKWGCKIKILREETIQHVQETAEEHLKIWXXXXXXXXXXXXXXXX---------EIESHKILMTEIFNTRESFELARIGMS-----------------------ETEKNV---ENEMKRLREHYQKLRSYTPTGENPPIAPYIWRIEEFTRKWQRARDGTEVSITSPPFYSWKNGYKLRMRVYPNGDGAGKDTHVSVFFVLVKGEWDELQSWPFSNKMAFTIM--SAKDAHVERLKPD-GAPCYNKPTADVGTAIGSPR---IMRQNVMWEYLEGDTLFVKWSV 2686
++EA+ C AC +L+ P Q +CG R C+ C+ + +GP+ C C E I+ L + D AA RE+ ++ CPN C W+G ++E S H C + C C+ + SE++ H E C +R C++C + HV+++ ++C +F C + CG +++I ++H CS+ R+ C GC + E H + EHL + + + + +I KI E + E+ R+ ++ + E+++ + M L + +L T G +IW+I +FTRK Q A G +I SP FY+ + GYK+ +RVY NGDG G+ TH+S+FFV++KG D L WPF+ K+ ++ + ++ ++ +PD + + +P +D+ A G P + + Y+ D +F+K V
Sbjct: 27 RLEAKYLCSACKNILRRPFQAQCGHRYCSFCLTSILSSGPQNCAACVYEGLYEEGISILESSSAFPDNAARREVESLPAVCPNDGCTWKGTLKEYESCHEGLCPFLLTECPACKGLVRLSEKEHHTEQECPKRSLSCQHC-------RAPCSHVDLEVHYEVCPKFPLTC-DGCG-KKKIPRETFQDHVRACSKCRVLCRFHTVGCSEMVETENLQDHELQRLREHLALLLSSFLEAQASPGTLNQVGPELLQRCQILEQKIATFENIVCVLNREVERVAVTAEACSRQHRLDQDKIEALSNKVQQLERSIGLKDLAMADLEQKVSELEVSTYDGV------FIWKISDFTRKRQEAVAGRTPAIFSPAFYTSRYGYKMCLRVYLNGDGTGRGTHLSLFFVVMKGPNDALLQWPFNQKVTLMLLDHNNREHVIDAFRPDVTSSSFQRPVSDMNIASGCPLFCPVSKMEAKNSYVRDDAIFIKAIV 496
BLAST of TNF receptor-associated factor vs. Ensembl Mouse
Match: Traf2 (TNF receptor-associated factor 2 [Source:MGI Symbol;Acc:MGI:101835]) HSP 1 Score: 169.474 bits (428), Expect = 1.644e-43 Identity = 130/492 (26.42%), Postives = 224/492 (45.53%), Query Frame = 2
Query: 1394 QIEARLRCGACTKLLKEPRQTECGCRLCTECIIE-------LTLNGPKQCPDC-----KETEIASLGETQE--DRAASREIMNMRIKCPNKPCNWEGKIREA-SAHLNQCRYKRKPCEKCQQPISESEEKQH-ENVCEERRTRCEYCNITETWKQIQQEHVNVK-EEKICDRFRGKCPNKCGVEEEI---ELKEHWERCSRKRIECPMAKWGCKIKILREETIQHVQETAEEHLKIWXXXXXXXXXXXXXXXX---------EIESHKILMTEIFNTRESFELARIGMS-----------------------ETEKNV---ENEMKRLREHYQKLRSYTPTGENPPIAPYIWRIEEFTRKWQRARDGTEVSITSPPFYSWKNGYKLRMRVYPNGDGAGKDTHVSVFFVLVKGEWDELQSWPFSNKMAFTIM--SAKDAHVERLKPD-GAPCYNKPTADVGTAIGSPR---IMRQNVMWEYLEGDTLFVKWSV 2686
++EA+ C AC +L+ P Q +CG R C+ C+ L+ +GP+ C C E I+ L + D AA RE+ ++ CPN C W+G ++E S H C + C C+ + SE++ H E C +R C++C + HV+++ ++C +F C + CG +++I ++H CS+ R+ C GC + E H + EHL + + + + +I KI E + E+ R+ ++ + E+++ + M L + +L T G +IW+I +FTRK Q A G +I SP FY+ + GYK+ +RVY NGDG G+ TH+S+FFV++KG D L WPF+ K+ ++ + ++ ++ +PD + + +P +D+ A G P + + Y+ D +F+K V
Sbjct: 27 RLEAKYLCSACKNILRRPFQAQCGHRYCSFCLTSILRCASILSSSGPQNCAACVYEGLYEEGISILESSSAFPDNAARREVESLPAVCPNDGCTWKGTLKEYESCHEGLCPFLLTECPACKGLVRLSEKEHHTEQECPKRSLSCQHC-------RAPCSHVDLEVHYEVCPKFPLTC-DGCG-KKKIPRETFQDHVRACSKCRVLCRFHTVGCSEMVETENLQDHELQRLREHLALLLSSFLEAQASPGTLNQVGPELLQRCQILEQKIATFENIVCVLNREVERVAVTAEACSRQHRLDQDKIEALSNKVQQLERSIGLKDLAMADLEQKVSELEVSTYDGV------FIWKISDFTRKRQEAVAGRTPAIFSPAFYTSRYGYKMCLRVYLNGDGTGRGTHLSLFFVVMKGPNDALLQWPFNQKVTLMLLDHNNREHVIDAFRPDVTSSSFQRPVSDMNIASGCPLFCPVSKMEAKNSYVRDDAIFIKAIV 503
BLAST of TNF receptor-associated factor vs. Ensembl Mouse
Match: Traf3 (TNF receptor-associated factor 3 [Source:MGI Symbol;Acc:MGI:108041]) HSP 1 Score: 144.05 bits (362), Expect = 9.781e-35 Identity = 124/511 (24.27%), Postives = 227/511 (44.42%), Query Frame = 2
Query: 1397 IEARLRCGACTKLLKEPRQTECGCRLCTECIIELTLNGPKQCPDCKETEIASLGETQEDRAASREIMNMRIKCPN--KPCNWEGKIREASAHL-NQCRYKRKPCEK--CQQPISESEEKQH-ENVCEERRTRCEYCNITETWKQIQQEHVNVKEEKICDRFRGKCPNKCGVEEEI-------ELKEHWERCSRKRIECPMAKWGC----KIKILREETIQHVQETAEEHLKIWXXXXXXXXXXXXXXXXEIESHKILMTEIFNTRESFELARIGMSETE--KNVENEMKRLREHYQKLRSYTPTGE---------------------------------NPPIAPYIWRIEEFTRKWQ-------------RARD----------GTEVSITSPPFYSWKNGYKLRMRVYPNGDGAGKDTHVSVFFVLVKGEWDELQSWPFSNKMAFTIM---SAKDAHVERLKPD-GAPCYNKPTADVGTAIGSPRIMRQNVM--WEYLEGDTLFVKWSV 2686
+E + +C C +L P+QTECG R C C+ L + +C C+E+ I + +D REI+ +++ C N + C + + HL N+C+++ PC + C++ + + + H E C+ R C +C ++Q+ E+ C CP+KC V+ + ++K H + + + + +W K+ +L+ E+++ + H +I +IEIE K ++ N + L R+ S+ E K ++ E++ R+++++ S + E + ++ + R+ + ++Q + RD G +S+ S PFY+ GYK+ RVY NGDG GK TH+S+FFV+++GE+D L WPF K+ +M S++ + KPD + + KPT ++ A G P + Q V+ Y++ DT+F+K V
Sbjct: 46 VEDKYKCEKCRLVLCNPKQTECGHRFCESCMAALLSSSSPKCTACQESIIKD--KVFKDNCCKREILALQVYCRNEGRGCAEQLTLGHLLVHLKNECQFEELPCLRADCKEKVLRKDLRDHVEKACKYREATCSHCKSQVPMIKLQKH-----EDTDCPCVVVSCPHKCSVQTLLRSEGTNQQIKAHEASSAVQHVNL-LKEWSNSLEKKVSLLQNESVEKNKSIQSLHNQIC------------SFEIEIERQKEMLRN--NESKILHLQRVIDSQAEKLKELDKEIRPFRQNWEEADSMKSSVESLQNRVTELESVDKSAGQAARNTGLLESQLSRHDQMLSVHDIRLADMDLRFQVLETASYNGVLIWKIRDYKRRKQEAVMGKTLSLYSQPFYTGYFGYKMCARVYLNGDGMGKGTHLSLFFVIMRGEYDALLPWPFKQKVTLMLMDQGSSRRHLGDAFKPDPNSSSFKKPTGEMNIASGCPVFVAQTVLENGTYIKDDTIFIKVIV 534
BLAST of TNF receptor-associated factor vs. Ensembl Mouse
Match: Traf3 (TNF receptor-associated factor 3 [Source:MGI Symbol;Acc:MGI:108041]) HSP 1 Score: 144.05 bits (362), Expect = 9.781e-35 Identity = 124/511 (24.27%), Postives = 227/511 (44.42%), Query Frame = 2
Query: 1397 IEARLRCGACTKLLKEPRQTECGCRLCTECIIELTLNGPKQCPDCKETEIASLGETQEDRAASREIMNMRIKCPN--KPCNWEGKIREASAHL-NQCRYKRKPCEK--CQQPISESEEKQH-ENVCEERRTRCEYCNITETWKQIQQEHVNVKEEKICDRFRGKCPNKCGVEEEI-------ELKEHWERCSRKRIECPMAKWGC----KIKILREETIQHVQETAEEHLKIWXXXXXXXXXXXXXXXXEIESHKILMTEIFNTRESFELARIGMSETE--KNVENEMKRLREHYQKLRSYTPTGE---------------------------------NPPIAPYIWRIEEFTRKWQ-------------RARD----------GTEVSITSPPFYSWKNGYKLRMRVYPNGDGAGKDTHVSVFFVLVKGEWDELQSWPFSNKMAFTIM---SAKDAHVERLKPD-GAPCYNKPTADVGTAIGSPRIMRQNVM--WEYLEGDTLFVKWSV 2686
+E + +C C +L P+QTECG R C C+ L + +C C+E+ I + +D REI+ +++ C N + C + + HL N+C+++ PC + C++ + + + H E C+ R C +C ++Q+ E+ C CP+KC V+ + ++K H + + + + +W K+ +L+ E+++ + H +I +IEIE K ++ N + L R+ S+ E K ++ E++ R+++++ S + E + ++ + R+ + ++Q + RD G +S+ S PFY+ GYK+ RVY NGDG GK TH+S+FFV+++GE+D L WPF K+ +M S++ + KPD + + KPT ++ A G P + Q V+ Y++ DT+F+K V
Sbjct: 46 VEDKYKCEKCRLVLCNPKQTECGHRFCESCMAALLSSSSPKCTACQESIIKD--KVFKDNCCKREILALQVYCRNEGRGCAEQLTLGHLLVHLKNECQFEELPCLRADCKEKVLRKDLRDHVEKACKYREATCSHCKSQVPMIKLQKH-----EDTDCPCVVVSCPHKCSVQTLLRSEGTNQQIKAHEASSAVQHVNL-LKEWSNSLEKKVSLLQNESVEKNKSIQSLHNQIC------------SFEIEIERQKEMLRN--NESKILHLQRVIDSQAEKLKELDKEIRPFRQNWEEADSMKSSVESLQNRVTELESVDKSAGQAARNTGLLESQLSRHDQMLSVHDIRLADMDLRFQVLETASYNGVLIWKIRDYKRRKQEAVMGKTLSLYSQPFYTGYFGYKMCARVYLNGDGMGKGTHLSLFFVIMRGEYDALLPWPFKQKVTLMLMDQGSSRRHLGDAFKPDPNSSSFKKPTGEMNIASGCPVFVAQTVLENGTYIKDDTIFIKVIV 534
BLAST of TNF receptor-associated factor vs. Ensembl Mouse
Match: Traf5 (TNF receptor-associated factor 5 [Source:MGI Symbol;Acc:MGI:107548]) HSP 1 Score: 137.502 bits (345), Expect = 1.475e-32 Identity = 127/520 (24.42%), Postives = 212/520 (40.77%), Query Frame = 2
Query: 1394 QIEARLRCGACTKLLKEPRQTECGCRLCTECIIELT-LNGPKQCPDCKETEIASLGETQEDRAASREIMNMRIKCPNKP-CNWEGKIREASAHLNQ-----------------------------CRYKRKPCEKCQQPISESEEKQHE-NVCEERRTRCEYCNITETWKQIQQEHVNVKEEKICDRFRGKCPNK---CGVE---------EEIELKEHWERCSRK------RIECPMAKWGCKIKILREET-IQHVQETAEEHLKIWXXXXXXXXXXXXXXXXEIESHKILMTEIFNTRES-FEL---------------------ARIGMSETEKNVEN--------EMKRLREHYQKLRSYTPTGENPPIAPYIWRIEEFTRKWQRARDGTEVSITSPPFYSWKNGYKLRMRVYPNGDGAGKDTHVSVFFVLVKGEWDELQSWPFSNKMAFTIM--SAKDAH-VERLKPD-GAPCYNKPTADVGTAIGSPRIMRQNVMWE----YLEGDTLFVKWSV 2686
Q+E R +C C +L P QT CG R C +CI L LN CP + E+ E +D RE++N+ + C N P CN + HL CR++ + C C++ I + + HE N C C + + EH+ V C CP K C V+ E L++H K R+ ++ K K+ ++ IQH I+ + +E+ + +I N + S +L R+ + E E + + ++ + E +++L +G+ IW++ ++ K + A +G VS+ S PFY+ + GY+L R Y NGDG+GK TH+S++FV+++GE+D L WPF ++ ++ S K H VE K D + + +P ++ A G PR + + + Y++ DTLF+K +V
Sbjct: 38 QLEERYKCAFCHSVLHNPHQTGCGHRFCQQCIRSLRELNSVPICP--VDKEVIKPQEVFKDNCCKREVLNLHVYCKNAPGCNARIILGRFQDHLQHCSFQAVPCPNESCREAMLRKDVKEHLSAYCRFREEKCLYCKRDIVVTNLQDHEENSCPAYPVSCPNRCVQTIPRARVNEHLTV-----CPEAEQDCPFKHYGCTVKGKRGNLLEHERAALQDHMLLVLEKNYQLEQRVNALLSSLERKKKMAAADSAIQHATNPMSRFQDIFSFLYRKALTSHTDKSAWLEAQVRQLLQIVNQQPSRLDLRSLVDAVDSVKQRITQLEASDQRLVLLEGETSKHDAHINIHKAQLNKNEERFKQLEGACYSGK------LIWKVTDYRVKKREAVEGHTVSVFSQPFYTSRCGYRLCARAYLNGDGSGKGTHLSLYFVVMRGEFDSLLQWPFRQRVTLMLLDQSGKKNHIVETFKADPNSSSFKRPDGEMNIASGCPRFVSHSTLENSKNTYIKDDTLFLKVAV 544
BLAST of TNF receptor-associated factor vs. UniProt/SwissProt
Match: sp|P39429|TRAF2_MOUSE (TNF receptor-associated factor 2 OS=Mus musculus OX=10090 GN=Traf2 PE=1 SV=1) HSP 1 Score: 174.866 bits (442), Expect = 1.628e-44 Identity = 129/485 (26.60%), Postives = 223/485 (45.98%), Query Frame = 2
Query: 1394 QIEARLRCGACTKLLKEPRQTECGCRLCTECIIELTLNGPKQCPDC-----KETEIASLGETQE--DRAASREIMNMRIKCPNKPCNWEGKIREA-SAHLNQCRYKRKPCEKCQQPISESEEKQH-ENVCEERRTRCEYCNITETWKQIQQEHVNVK-EEKICDRFRGKCPNKCGVEEEI---ELKEHWERCSRKRIECPMAKWGCKIKILREETIQHVQETAEEHLKIWXXXXXXXXXXXXXXXX---------EIESHKILMTEIFNTRESFELARIGMS-----------------------ETEKNV---ENEMKRLREHYQKLRSYTPTGENPPIAPYIWRIEEFTRKWQRARDGTEVSITSPPFYSWKNGYKLRMRVYPNGDGAGKDTHVSVFFVLVKGEWDELQSWPFSNKMAFTIM--SAKDAHVERLKPD-GAPCYNKPTADVGTAIGSPR---IMRQNVMWEYLEGDTLFVKWSV 2686
++EA+ C AC +L+ P Q +CG R C+ C+ + +GP+ C C E I+ L + D AA RE+ ++ CPN C W+G ++E S H C + C C+ + SE++ H E C +R C++C + HV+++ ++C +F C + CG +++I ++H CS+ R+ C GC + E H + EHL + + + + +I KI E + E+ R+ ++ + E+++ + M L + +L T G +IW+I +FTRK Q A G +I SP FY+ + GYK+ +RVY NGDG G+ TH+S+FFV++KG D L WPF+ K+ ++ + ++ ++ +PD + + +P +D+ A G P + + Y+ D +F+K V
Sbjct: 27 RLEAKYLCSACKNILRRPFQAQCGHRYCSFCLTSILSSGPQNCAACVYEGLYEEGISILESSSAFPDNAARREVESLPAVCPNDGCTWKGTLKEYESCHEGLCPFLLTECPACKGLVRLSEKEHHTEQECPKRSLSCQHC-------RAPCSHVDLEVHYEVCPKFPLTC-DGCG-KKKIPRETFQDHVRACSKCRVLCRFHTVGCSEMVETENLQDHELQRLREHLALLLSSFLEAQASPGTLNQVGPELLQRCQILEQKIATFENIVCVLNREVERVAVTAEACSRQHRLDQDKIEALSNKVQQLERSIGLKDLAMADLEQKVSELEVSTYDGV------FIWKISDFTRKRQEAVAGRTPAIFSPAFYTSRYGYKMCLRVYLNGDGTGRGTHLSLFFVVMKGPNDALLQWPFNQKVTLMLLDHNNREHVIDAFRPDVTSSSFQRPVSDMNIASGCPLFCPVSKMEAKNSYVRDDAIFIKAIV 496
BLAST of TNF receptor-associated factor vs. UniProt/SwissProt
Match: sp|Q12933|TRAF2_HUMAN (TNF receptor-associated factor 2 OS=Homo sapiens OX=9606 GN=TRAF2 PE=1 SV=2) HSP 1 Score: 150.599 bits (379), Expect = 1.882e-36 Identity = 123/493 (24.95%), Postives = 220/493 (44.62%), Query Frame = 2
Query: 1394 QIEARLRCGACTKLLKEPRQTECGCRLCTECIIELTLNGPKQCPDCKETEI----ASLGETQE---DRAASREIMNMRIKCPNKPCNWEGKIREASA---------------------------HL-NQCRYKRKPCEKCQQPISESEEKQHENVCEERRTRCEYCNITETWKQIQQEHVNVKEEKICDRFRGKCP-NKCGVEEEIE-----------LKEHWERCSRKRIEC-PM----AKWGCKIKILREETIQHVQETAEEHLKIWXXXXXXXXXXXXXXXXE--IESHKI--LMTEIFNTRESFELARIGMSETEKNVENEMKRLREHYQKLRSYTPTGENPPIAPYIWRIEEFTRKWQRARDGTEVSITSPPFYSWKNGYKLRMRVYPNGDGAGKDTHVSVFFVLVKGEWDELQSWPFSNKMAFTIM--SAKDAHVERLKPD-GAPCYNKPTADVGTAIGSPR---IMRQNVMWEYLEGDTLFVKWSV 2686
++EA+ C AC +L+ P Q +CG R C+ C+ + +GP+ C C I S+ E+ D AA RE+ ++ CP+ C W+G ++E + HL ++C + C C+ P ++ K H VC + C+ C + ++ Q+HV K C + R C + G E +E L+EH +E P+ + G ++ + R E+++ T E + + ++ + + ++ KI L +++ S L + M++ E+ V ++ + T G +IW+I +F RK Q A G +I SP FY+ + GYK+ +R+Y NGDG G+ TH+S+FFV++KG D L WPF+ K+ ++ + ++ ++ +PD + + +P D+ A G P + + Y+ D +F+K V
Sbjct: 27 KLEAKYLCSACRNVLRRPFQAQCGHRYCSFCLASILSSGPQNCAACVHEGIYEEGISILESSSAFPDNAARREVESLPAVCPSDGCTWKGTLKEYESCHEGRCPLMLTECPACKGLVRLGEKERHLEHECPERSLSCRHCRAPCCGADVKAHHEVCPKFPLTCDGCGKKKIPREKFQDHV-----KTCGKCRVPCRFHAIGCLETVEGEKQQEHEVQWLREHLAMLLSSVLEAKPLLGDQSHAGSEL-LQRCESLEKKTATFENIVCVLNREVERVAMTAEACSRQHRLDQDKIEALSSKVQQLERSIGLKDLAMADLEQKV-----------LEMEASTYDGV------FIWKISDFARKRQEAVAGRIPAIFSPAFYTSRYGYKMCLRIYLNGDGTGRGTHLSLFFVVMKGPNDALLRWPFNQKVTLMLLDQNNREHVIDAFRPDVTSSSFQRPVNDMNIASGCPLFCPVSKMEAKNSYVRDDAIFIKAIV 496
BLAST of TNF receptor-associated factor vs. UniProt/SwissProt
Match: sp|Q6DJN2|TRF6B_XENLA (TNF receptor-associated factor 6-B OS=Xenopus laevis OX=8355 GN=traf6-b PE=2 SV=1) HSP 1 Score: 138.272 bits (347), Expect = 6.335e-32 Identity = 120/480 (25.00%), Postives = 203/480 (42.29%), Query Frame = 2
Query: 1397 IEARLRCGACTKLLKEPRQTECGCRLCTECIIELTLNGPKQCPDCKETEIASLGETQEDRAASREIMNMRIKCPNKPCNWEGKIREASAHLNQCRYKRKPCEKCQQPISESE-EKQHENVCEERRTRCEYCNITETWKQIQQEHVNVKEEKICDRFRGKCPNKCGVEEEIELKEHWER-CSRKRIECPMAKWGCKIKILREETIQHVQETAEEHLKIWXXXXXXXXXXXXXXXXEIE-----------------------SHKILMTEIFNTRESFE-----LAR--------IGMSETEKNVENEMKR-LREHYQKLRSYTPTGENPPIAPYIWRIEEFTRKWQRARDGTEVSITSPPFYSWKNGYKLRMRVYPNGDGAGK-DTHVSVFFVLVKGEWDELQSWPFSNKMAFTIMSAKDA-------HVERLKPDGAPCYNKPTADVGT-AIGSPRIMRQNVM--WEYLEGDTLFVKWSV 2686
+E++ C C L+E QT CG R C CI++ + +CP + EI + D A REI+++++KCP++ C ++R HL QC++ C +CQ +S EK E+ C R+ C+ C + ++ + E IC C ++ H+ C+ I C ++GC K+ R + +H+Q+ + H+++ T+++ +I SH+ E N RE+ E L R I ET+ NE+K +R KL N +IW+I+ F+ + + V I SP FY+ K GYKL +R++ A + ++S+F ++GE+D L WP + +I+ + V KPD + +PT G M N + +Y++ DTLFV+ +V
Sbjct: 66 LESKYECPICLMALREAVQTPCGHRFCKACIVKSLRDAGHKCP--VDNEILMENQLFPDNFAKREILSLKVKCPSQGCTETMELRHLERHLGQCQFASVECSQCQGSFPKSRLEKHMEHECGRRKIFCDNCGLAMAYEDMS------GHELICPLAYVTCEYCQTNLIREQMPSHYSMDCTMAPIPCMYYEFGCTEKMQRNDLARHLQDFTQAHMRMMFQTLRSFSTTPTSHISDISFCDPNQFEPVPLSVAPAHPSHMPSHQDCSQETRNLRETIEQLEGRLVRQDHQIRELIAKMETQCTYVNELKHTIRSLEDKLLDVDGHHCN---GVFIWKIKGFSGLQKTQEEEKPVVIHSPGFYTGKPGYKLCLRLHLQLPSAQRCANYISLFVHTMQGEYDSLLPWPLHGTIRLSILDQSEGAIIQDQEEVMDTKPDLL-AFQRPTTQRNPKGFGYVTFMHLNTLKQRQYVKNDTLFVRCAV 533
BLAST of TNF receptor-associated factor vs. UniProt/SwissProt
Match: sp|Q3MV19|TRF6A_XENLA (TNF receptor-associated factor 6-A OS=Xenopus laevis OX=8355 GN=traf6-a PE=1 SV=1) HSP 1 Score: 135.961 bits (341), Expect = 3.101e-31 Identity = 124/484 (25.62%), Postives = 205/484 (42.36%), Query Frame = 2
Query: 1397 IEARLRCGACTKLLKEPRQTECGCRLCTECIIELTLNGPKQCPDCKETEIASLGETQEDRAASREIMNMRIKCPNKPCNWEGKIREASAHLNQCRYKRKPCEKCQQPISESEEKQH-ENVCEERRTRCEYCNITETWKQIQQEHVNVKEEKICDRFRGKCPNKCGVEEEIE-LKEHWER-CSRKRIECPMAKWGCKIKILREETIQHVQETAEEHLKIWXXXXXXXXXXXXXXXXEIE-----------------------SHKILMTEIFNTRESFE-----LAR--------IGMSETEKNVENEMKR----LREHYQKLRSYTPTGENPPIAPYIWRIEEFTRKWQRARDGTEVSITSPPFYSWKNGYKLRMRVYPNGDGAGK-DTHVSVFFVLVKGEWDELQSWPFSNKMAFTIM-----SAKDAHVERL--KPDGAPCYNKPTADVGT-AIGSPRIMRQNVM--WEYLEGDTLFVKWSV 2686
+E++ C C L+E QT CG R C CI++ N +CP + EI + D A REI+++R+KCPN C ++R HL QC++ C +CQ + +H E+ C RRT C+ C + ++ E IC C + C E + H+ C+ I C ++GC+ K+ R H+Q+ + H+++ T+++ +I S + E N RE+ E L R I ET+ NE+K L + + ++ G +IWRI+ F+ + + V I SP FY+ GYKL +R++ A + ++S+F ++G++D L WP + +I+ +A+ VE + KPD + +PTA G M N + +Y++ DTL V+ SV
Sbjct: 66 LESKYECPICLMALREAVQTPCGHRFCKACILKSLRNAGHKCP--VDNEILMEKQLFPDNFAKREILSLRVKCPNLGCTDTMELRHLEHHLVQCQFASVECSQCQGSFLKLLLDKHMEHECGRRRTFCDNCGLAMAYED------KSGHELICPMAYVTC-DYCQTNLIREQMPAHYSMDCTMAPIPCMYCEFGCREKMQRHNLAGHLQDFTQAHMRMMAQTLRSFSTTPTSHISDISFCDPNQFEPVPLSVAPAHPSHMPSQQDCSQETRNLRETVEQLEGRLVRQDHQIRELIAKMETQCTYVNELKHTIHSLEDKVADMDAHRCNGV------FIWRIKGFSGLQKSQEEEKPVVIHSPGFYTGDPGYKLCLRLHLQLPSAQRCANYISLFVHTMQGDYDSLLPWPLQGTIRLSILDQSESTARQDQVEVMDTKPDLL-AFQRPTAPRNPKGFGYVTFMHLNTLKQRQYVKNDTLLVRCSV 533
BLAST of TNF receptor-associated factor vs. UniProt/SwissProt
Match: sp|Q61382|TRAF4_MOUSE (TNF receptor-associated factor 4 OS=Mus musculus OX=10090 GN=Traf4 PE=1 SV=2) HSP 1 Score: 134.035 bits (336), Expect = 4.751e-31 Identity = 114/499 (22.85%), Postives = 195/499 (39.08%), Query Frame = 2
Query: 1406 RLRCGACTKLLKEPRQ-TECGCRLCTECIIELTLNGPKQCPDCKETEIASLGETQEDRAASREIMNMRIKCPN--KPCNWEGKIREASAHLNQCRYKRKPC-EKCQQPISESEEKQH-ENVCEERRTRCEYCNITETWKQIQQEHVNVKEEKI------------------------------------------------CDRFRGKCPNKCGVEEEI--ELKEHW-ERCSRKRIECPMAKWGCKIKILREETIQHVQETAEEHLKIWXXXXXXXXXXXXXXXXEIESHKILMTEIFNTRESFELARIGMSETEKNVENEMKRLREHYQKLRSYTPTGENPPIAPYIWRIEEFTRKWQRARDGTEVSITSPPFYSWKNGYKLRMRVYPNGDGAGKDTHVSVFFVLVKGEWDELQSWPFSNKMAFTIMS------AKDAHV-ERLKPDGA-PCYNKPTADVGT------AIGSPRIMRQNVMWE--YLEGDTLFVKWSV 2686
RL C C K ++EP Q + CG R C C+ E G +CP+ + + D +++ + I+C + + C W G +R HLN C + PC +C +S + H ++ C +RR +CE+C + + + +E + C R CPN+CGV +L H + CS + CP + GCK + + +HV+E+ + HL + M E++ LR ++L G + IW+I + R+ Q A+ + SP FY+ K GYKL++ + NG+G+G+ TH+S++ ++ G +D L WPF+ ++ F+++ AK HV E PD + KP G+ G P+ + + + Y+ D +F++ SV
Sbjct: 15 RLLCPLCGKPMREPVQVSTCGHRFCDTCLQEFLSEGVFKCPE--DQLPLDYAKIYPDPELEVQVLGLAIRCIHSEEGCRWSGPLRHLQGHLNTCSFNVVPCPNRCPAKLSRRDLPAHLQHDCPKRRLKCEFCGCDFSGEAYESHEGVCPQESVYCENKCGARMMRRLLAQHATSECPKRTQPCAYCTKEFVYDTIQSHQYQCPRLPVPCPNQCGVGTVAREDLPTHLKDSCSTAFVLCPFKESGCKHRCPKLAMGRHVEESVKPHLAM------------------------------------------MCALVSRQRQELQELRRELEELS----IGSD---GVLIWKIGSYGRRLQEAKAKPNLECFSPAFYTHKYGYKLQVSAFLNGNGSGEGTHLSIYIRVLPGAFDNLLEWPFARRVTFSLLDQSDPGLAKPQHVTETFHPDPNWKNFQKPGTWRGSLDESSLGFGYPKFISHQDIRKRNYVRDDAVFIRASV 462
BLAST of TNF receptor-associated factor vs. TrEMBL
Match: D5JG60 (TNF receptor-associated factor-2-like protein B OS=Dugesia japonica OX=6161 GN=TRAF-2B PE=2 SV=1) HSP 1 Score: 244.202 bits (622), Expect = 2.409e-66 Identity = 143/445 (32.13%), Postives = 227/445 (51.01%), Query Frame = 2
Query: 1376 RKQTQIQIEARLRCGACTKLLKEPRQTECGCRLCTECIIELTLNGPKQCPDCKETEIASLGETQEDRAASREIMNMRIKCPNKPCNWEGKIREASAHLNQCRYKRKPCEKCQQPISESEEKQH-ENVCEERRTRCEYCNITETWKQIQQEHVNVKEEKICDRFRGKCPNKCGVEEEIELKEHWERCSRKRIECPMAKWGCKIKILREETIQHVQETAEEHLKIWXXXXXXXXXXXXXXXXEIESHKILMTEIFNTRESFELARIGMSETEKNVENEMKRLRE---HYQKLRSYTPTGENPPI---APYIWRIEEFTRKWQRARDGTEVSITSPPFYSWKNGYKLRMRVYPNGDGAGKDTHVSVFFVLVKGEWDELQSWPFSNKMAFTIMSAKDA---HVERLKPDG-APCYNKPTADVGTAIGSPRIMRQNVMWE-YLEGDTLFV 2674
+K I L+C C++LL E QT+CGCR C EC+ E G +C LG D A +REI + +KC C +++ HL+ C ++ C+ C + +++ E K+H E C R C +C + + + H+NV EK+C + GKCP KC +E+ L +H + CS+K + C ++ GC + +E+ I+H E + +H ++ M EI + K ++E+ F + +I S+ + + +++K L + H S + E + +IW+IE F+ A G +SITS FY+ + GYK+ M++YP GDG GK TH+SVFF L++GE+D+L WPF NK+ TI+ K+ H + KPD + CY +PT D A GSP+ + + + E YL LF
Sbjct: 17 KKHFPFNISDNLKCIICSQLLLEALQTDCGCRYCKECLKEYQAKGKTKCL---TDGCGDLGNIIPDNAVNREIGKLTVKCLFPGCEHSELLKDIGDHLDSCIHQTINCKSCNEELTKIELKEHTEKKCPMRLVSCTHCGEEMEYSNLTELHLNVHTEKLCAKLVGKCPYKCDNGKEVNLLDHRKSCSKKPVTCLFSEIGCNRVMTKEDLIKHNNEESLQHSRLLMK--------------EIITMKNDISELKMKTLEFNILKIEFSKFQSEILDKIKSLEKIPRHTSPSTSSVRSSEEKTVYRNGVFIWKIERFSELKSEAERGNRISITSDYFYTKEFGYKMSMKIYPAGDGVGKGTHLSVFFTLMRGEFDDLLQWPFKNKVTLTILDQKNKTNDHSDTFKPDVRSTCYQQPTDDYNIASGSPKFITFSQLDEIYLXXXILFF 444
BLAST of TNF receptor-associated factor vs. TrEMBL
Match: T1DBK6 (TRAF-4 OS=Dendrocoelum lacteum OX=27895 PE=2 SV=1) HSP 1 Score: 226.483 bits (576), Expect = 3.327e-60 Identity = 130/443 (29.35%), Postives = 224/443 (50.56%), Query Frame = 2
Query: 1388 QIQIEARLRCGACTKLLKEPRQTECGCRLCTECIIELTLNGPKQCP----DCKETEIASLGETQEDRAASREIMNMRIKCPNKPCNWEGKIREASAHLNQCRYKRKPCEKCQQPISESEEKQH-ENVCEERRTRCEYCNITETWKQIQQEHVNVKEEKICDRFRGKCPNKCGVEEEIELKEHWERCSRKRIECPMAKWGCKIKILREETIQHVQETAEEH-LKIWXXXXXXXXXXXXXXXXEIESHKILMTEIFNTRESFELARIGMSETEKNVENEMKRLREHYQKLRSYTPTGENPPIAPYIWRIEEFTRKWQRARDGTEVSITSPPFYSWKNGYKLRMRVYPNGDGAGKDTHVSVFFVLVKGEWDELQSWPFSNKMAFTIMS--AKDAHV-ERLKPD-GAPCYNKPTADVGTAIGSPRIMRQNVMWEYLEGDTLFVKWSV 2686
+ I L+C C +L + QT+CGCR C ECI NG K+C DC+ + + DRA ++EI +++KC + C +E ++ HL+ C Y+ + C C EE H N C R C+YC T+K+ + H+ + +C ++ CP C E ++ L H + C K +ECP+ + CK I +++ +H+ ++ EH L I + K Q E IL+ E + + E+ ++ + + ++ + R + R+ Y+W+I+ F++ + A G +I S FY+ GYK+ M++YP GDG GK TH+S+FFV++KG++D++ WPF NK+ TI +K ++ + KPD + CY +P + A GSP+ + + + +L+ DTL+++ +V
Sbjct: 22 RFTINDNLKCVMCQDILLDAIQTDCGCRYCKECIDNYLENGEKECVAEYEDCRSVITSYI----YDRATNKEISLLKVKCLYEGCVFEDTLKSIKGHLDFCEYRNEMCSLCGMEYIIKEESNHLANECLLREVLCQYCRTLLTFKEYNESHLCFESRDLCGKYEAICPYGCTGESKVNLLHHRKSCENKPLECPLHVFDCKQLIPKDQMTEHLNTSSYEHTLTIVTELRKLEKQNKHME----ERMNILIEENQLLKATLEVMKLDLPKNSGSISRDTSLKRANKTIFRN----------GKYMWKIKSFSKLRENAMRGKNPTILSEAFYTSDFGYKMCMKIYPCGDGVGKGTHLSIFFVIMKGDYDDILPWPFKNKVIITIFDDFSKSTNLSDTFKPDPKSICYQRPEEEYNIASGSPKFISFSELKNFLKKDTLYIQINV 446
BLAST of TNF receptor-associated factor vs. TrEMBL
Match: A0A4W5P175 (TNF receptor-associated factor OS=Hucho hucho OX=62062 PE=3 SV=1) HSP 1 Score: 211.846 bits (538), Expect = 5.660e-55 Identity = 133/454 (29.30%), Postives = 243/454 (53.52%), Query Frame = 2
Query: 1391 IQIEARLRCGACTKLLKEPRQTECGCRLCTECIIELTLNGPKQCPDCKETE-------IASLGETQEDRAASREIMNMRIKCPNKPCNWEGKIREASA-HLNQCRYKRKPCEKCQQPISESEEKQH-ENVCEERRTRCEYCNITETWKQIQQEHVNVKEEKICDRFRGKCPNKCGVEE--EIELKEHWERCSRKRIECPMAKWGCKIKILREETIQHVQETAEEHLKIWXXXXXXXXXXXXXXXXEIESHKILMTEIFNTRESFELARI-GMSETEKNVENEMK----RLREHYQKLRSYTPTGENPPIAPYIWRIEEFTRKWQRARDGTEVSITSPPFYSWKNGYKLRMRVYPNGDGAGKDTHVSVFFVLVKGEWDELQSWPFSNKMAFTIM--SAKDAHVERLKPD-GAPCYNKPTADVGTAIGSPR---IMRQNVMWEYLEGDTLFVKWSV 2686
+ +E + +C C ++L++P Q +CG R C C+ LT +GPK C C++ E I + E D AA REI ++ KC ++ C+W G I+E A H +C Y+R PCE CQ I SE+++H E CE R C+YC ++ +K+I+ ++IC +F +C + CG ++ + +H + C++ + CP ++ GCK+ + + + H + + + ++ ++ ++ + E+E + + E F+ + + +I +S + +E + +L E Q LR + ++W+I +F+R+ Q A G ++ SP FYS K GYK+ +R+Y NGDG G+ TH+S+FFV+++G+ D L WPFS K+ ++ + ++ ++ +PD + + +P +++ A G P + + YL DT+F+K V
Sbjct: 23 VSMETKYQCQQCHQVLRKPVQAQCGHRFCVHCLKLLTSSGPKPCEACRQEEIYEEPQSILNSNEAFPDNAAGREIASLPAKCISEGCSWTGCIKEYEAQHEGKCEYERVPCETCQVLILRSEKERHNERECEARTLNCKYCKVSFNFKEIK------AHDEICQKFPMQCKD-CGKKKIPREKFLDHSKSCAKSKTACPFSEVGCKVVVDVADAVTHNEGLVFIVFSVVVLQVRALENIVCVLNREVERSSLTL-EAFSRQHRLDQDKIENLSNKVRQLERTLTMRDLQLAETDQTLRELQFCTFD---GVFVWKIADFSRRRQDAVAGRTPAMFSPAFYSSKYGYKMCLRLYLNGDGTGRGTHLSLFFVVMRGKCDALLKWPFSQKVTLMLLDQNNREHIIDAFRPDVTSTSFQRPISEMNIASGCPLFCPLAKLAGKSSYLRDDTIFIKAIV 465
BLAST of TNF receptor-associated factor vs. TrEMBL
Match: T1DF65 (TRAF-2 OS=Dendrocoelum lacteum OX=27895 PE=2 SV=1) HSP 1 Score: 211.46 bits (537), Expect = 7.001e-55 Identity = 126/449 (28.06%), Postives = 231/449 (51.45%), Query Frame = 2
Query: 1361 IIEIIRKQTQI------QIEARLRCGACTKLLKEPRQTECGCRLCTECIIELTLNGPKQCPDCKETEIASLGETQEDRAASREIMNMRIKCPNKPCNWEGKIREASAHLNQCRYKRKPCEKCQQPISESEEKQHEN-VCEERRTRCEYCNITETWKQIQQEHVNVKE--EKICDRFRGKCPNKCGVEEEIELKEHWERCSRKRIECPMAKWGCKIKILREETIQHVQETAEEHLKIWXXXXXXXXXXXXXXXXEIESHKILMTEIFNTRESFELARIG------MSETEKNVENEMKRLREHYQKLR--------SYTPTGENPPIAPYIWRIEEFTRKWQRARDGTEVSITSPPFYSWKNGYKLRMRVYPNGDGAGKDTHVSVFFVLVKGEWDELQSWPFSNKMAFTIMSAK---DAHVERLKPD-GAPCYNKPTADVGTAIGSPRIM 2626
++++I+ ++++ Q + R+ C C ++L EP QT+CGCRLC+ C+ E + + CP C ET + ++ D+A +EI+ + I C NK C + K+++ HL C Y K C C + E K+HE C+ T CE C + + ++++H NV E + +C ++R CP KC + + +K+H C R+ +EC + + GC+ + REE +H A H + MD + + + + + + + N R S E+ + ++E E +++ ++K+ + Y+KL S + T E Y W++E K A+ G I S FYS GY++ +++YPNGDG+ ++SV+FVL+KG++D+ WPF++ ++ +++ + V ++P+ CY +P + A G P+ +
Sbjct: 8 VLKVIKDRSKLFYFECEQQKQRISCVKCHQVLIEPYQTQCGCRLCSNCLEECSKDEESHCPGCNETMNSPSNYSKHDKAIEKEILELNIICTNKGCEYTCKVKDLDNHLETCEYIEKRCTACNESYPRKELKKHEEFTCKMIITTCEDCGLELSKGDLEKKHKNVNELIDNVCSKWRDICPFKCSEDTLVNIKDHLLTCERRPVECSLNEMGCRKVLPREEMREHFNLEANYHTVLLMDALFLLRKEHQDLSVSV--------SVQNERNSAEIKELKEKLSSLLTEIE-DLKTKLKQFQSMYEKLENERNLAKCSLSETKER--YGEYTWKVENIMEKVNDAKKGVNTQILSESFYSSNPGYRMCLKIYPNGDGSAFGNYLSVYFVLMKGKYDDQIQWPFNSIISIRLVNIARRGEDRVLNMRPNINDQCYGRPKEEHNLAAGQPKFV 445
BLAST of TNF receptor-associated factor vs. TrEMBL
Match: A0A4W4H2M4 (TNF receptor-associated factor OS=Electrophorus electricus OX=8005 GN=LOC113588078 PE=3 SV=1) HSP 1 Score: 211.075 bits (536), Expect = 1.488e-54 Identity = 129/461 (27.98%), Postives = 234/461 (50.76%), Query Frame = 2
Query: 1370 IIRKQTQIQIEARLRCGACTKLLKEPRQTECGCRLCTECIIELTLNGPKQCPDCK-------ETEIASLGETQEDRAASREIMNMRIKCPNKPCNWEGKIREASA-HLNQCRYKRKPCEKCQQPISESEEKQH-ENVCEERRTRCEYCNITETWKQIQQEHVNVKEEKICDRFRGKCPNKCGVEE--EIELKEHWERCSRKRIECPMAKWGCKIKILREETIQHVQETAEEHLKIWXXXXXXXXXXXX-XXXXEIESHKILMTEIFN----TRESFELARIGMSETEKNVENEMKRLREHYQKLRSYTPTGENPPIAPYIWRIEEFTRKWQRARDGTEVSITSPPFYSWKNGYKLRMRVYPNGDGAGKDTHVSVFFVLVKGEWDELQSWPFSNKMAFTIMSAKDAH--VERLKPD-GAPCYNKPTADVGTAIGSPR---IMRQNVMWEYLEGDTLFVKWSV 2686
I R+ + +E + +C C ++L++P Q +CG R C C ELT +GP C C+ + + ++ E D AA REI ++ KCPN+ C+W G +++ H +C ++R CE CQ I S+ +H E CE R C+YC ++ +K I+ ++IC +F +C + CG ++ + +EH + C++ + C + GC+ + + +H Q + EHL++ + + + + E+E + + + +E E + + E+ + +L E Q LR + +IW+I +F+ + Q A G ++ SP FYS K GYK+ +R+Y NGDG G++TH+S+FFV+++G++D L WPF K+ ++ + ++ +PD + + +P +++ A G P + + YL DT+F+K V
Sbjct: 27 ISRQVLSVSMEPKYQCQQCKEVLRKPFQAQCGHRFCVFCFKELTSSGPIPCEACRAEGIFEEQLSMLNITEAFPDNAARREIDSLPAKCPNEGCSWTGTLKDYEGQHEGRCEFERVTCEACQVLILLSDRDRHNERECEARTLNCKYCKVSFNFKDIK------AHDEICQKFPMQCKD-CGKKKIPREKFQEHSKSCAKSKSACQFREIGCRAVVDNGKQHEHEQASITEHLRLMLADKMTALENIACVLNREVERTALTLEALTRQHRLDQEKIESLSTKVRQLERTLTMRDLKLAESEQSLRELQFCTYD---GMFIWKISDFSHRRQDALAGRSPALFSPAFYSSKYGYKMCLRLYMNGDGTGRNTHLSLFFVVMRGKYDALLKWPFGQKVTLMLLDQNNREHIIDAFRPDTSSTSFQRPISEMNIASGCPLFCPLAKLAGKSSYLRDDTIFIKAIV 477
BLAST of TNF receptor-associated factor vs. Ensembl Cavefish
Match: traf2a (TNF receptor-associated factor 2-like [Source:NCBI gene;Acc:103036375]) HSP 1 Score: 145.591 bits (366), Expect = 5.109e-36 Identity = 120/474 (25.32%), Postives = 205/474 (43.25%), Query Frame = 2
Query: 1376 RKQTQIQIEARLRCGACTKLLKEPRQTECGCRLCTECIIELTLNGPKQCPDCKETEIASLGETQEDRAASREIMNMRIKCPNKPCNWEGKIREASA-HLNQCRYKRKPCEKCQQPISESE-EKQHENVCEERRTRCEYCNITETWKQIQ-QEHVNVKEEKICDRFRGKCPNKCGVEEEIELKEHWERCSRKRIECPMAKWGCKIK--------ILREETIQHVQETA---------------EEHLKIWXXXXXXXXXXXXXXXXEIESHKILMTEIFN-----TRESFELARIGMSETEKNVENEMKRLREHYQKLRSYTPTGENPPIAPYIWRIEEFTRKWQRARDGTEVSITSPPFYSWKNGYKLRMRVYPNGDGAGKDTHVSVFFVLVKGEWDELQSWPFSNKMAFTIM--SAKDAHVERLKPD-GAPCYNKPTADVGTAIGSPR---IMRQNVMWEYLEGDTLFVKWSV 2686
RK ++E + C C K+L+ P Q +CG R S D AA RE+ + C N+ C+W G I+E A H QC + PC C++ + +E E+ +E C ER C+YC +K I+ + + K IC+ G K E+ ++ H + C++ R C GC + IL + + T E LK+ E+E M E +N ++ E+ + + E+ V + E K+R + + ++W+I +F++K Q A G ++ SP FY+ K GYK+ +R+Y NGDG G+ TH+S+FFV+++G D L WPF+ K+ ++ + ++ ++ +PD + + +P +D+ A G P + + + Y+ DT+F+K V
Sbjct: 21 RKILANKLEDKHLCNICQKILRRPFQAQCGHRF-------------------------SPASAFPDNAAKREVEALEAVCINEGCSWTGTIKEYEATHEGQCDFMIIPCPSCKELLRANELERHNERECPERTLNCKYCKEPFHFKNIKAHDEICPKYPMICE---GCAKKKIPREKYVD---HIKLCTKFRTPCRFHVVGCDMSVSKPQWNLILTPRDLLYTSFTVPLSQTKVAELSRRCQELELKVGTFENIVCVLNR-----EMERSATTM-EAYNRQHRLDQDKIEILNNKVRQLERTVGLRDLSIVEMEGKMREMSAATYD---GVFVWKISDFSKKRQDAVAGRAPAMFSPAFYTSKYGYKMCLRIYLNGDGTGRGTHLSLFFVVMRGHSDALLKWPFNQKVTLMLLDQNNREHIIDAFRPDISSSSFQRPVSDMNIASGCPLFCPLSKLDSKNSYIRDDTIFIKAIV 454
BLAST of TNF receptor-associated factor vs. Ensembl Cavefish
Match: traf4a (TNF receptor associated factor 4 [Source:NCBI gene;Acc:103024022]) HSP 1 Score: 136.346 bits (342), Expect = 9.052e-33 Identity = 110/501 (21.96%), Postives = 203/501 (40.52%), Query Frame = 2
Query: 1406 RLRCGACTKLLKEPRQ-TECGCRLCTECIIELTLNGPKQCPDCKETEIASLGETQEDRAASREIMNMRIKCPN--KPCNWEGKIREASAHLNQCRYKRKPC-EKCQQPISESEEKQH-ENVCEERRTRCEYCNITETWKQIQQEHVNVKEEKI------------------------------------------------CDRFRGKCPNKCGVEEEI--ELKEHW-ERCSRKRIECPMAKWGCKIKILREETIQHVQETAEEHLKIWXXXXXXXXXXXXXXXXEIESHKILMTEIFNTR--ESFELARIGMSETEKNVENEMKRLREHYQKLRSYTPTGENPPIAPYIWRIEEFTRKWQRARDGTEVSITSPPFYSWKNGYKLRMRVYPNGDGAGKDTHVSVFFVLVKGEWDELQSWPFSNKMAFTIMSAKDAHV-------ERLKPDG------APCYNKPTADVGT-AIGSPRIMRQNVMWE--YLEGDTLFVKWSV 2686
R +C C+K ++EP Q + CG R C C+ E G +CP+ + + D ++I+ + I+C + + C W G++++ H + C + PC +C ++ + +H ++ C +R+ +CE+C T + + +E + C RF +CPN+CG +L H E C + CP GCK + + +H++ET + SH +M + + E EL R EM+ L + + IW++ +++RK Q A+ SPPFY+ + GYKL++ + NG+G+G+ +H+S++ ++ GE+D L WPF+ K+ F+I+ D + E PD P ++ + D T G P+ + + + + Y+ + +F+K S+
Sbjct: 15 RFQCPLCSKAMREPVQVSTCGHRFCDTCLQEFLSEGVFKCPE--DQLPLDYAKIYPDPELEQQILALPIRCIHSEEGCRWTGQMKQLQGHFSTCAFNVIPCPNRCAVKLTRRDLPEHLQHDCPKRKVKCEFCGSEFTGEAFENHQGICPQESVYCENKCGARMMRRLLAQHTMAECPKRTQPCKYCGKEFVYDTIQNHQYHCPRFPVQCPNQCGTPNIAREDLATHVKESCGSALVLCPFKDAGCKHRCPKLAIGRHLEETTK-------------------------SHLTMMCSLVGRQRQEIIELRR------------EMEELSVSHDGV--------------LIWKLNDYSRKLQEAKLHNNHEFFSPPFYTHRYGYKLQVSAFLNGNGSGEGSHLSIYIRVLPGEYDNLLEWPFAYKVTFSILDQSDPSLSKPQHITETFNPDPNWKNFQKPSSSRNSLDESTLGFGYPKFISHDEIRKRNYIRDNAIFLKASI 462
BLAST of TNF receptor-associated factor vs. Ensembl Cavefish
Match: traf6 (TNF receptor associated factor 6 [Source:NCBI gene;Acc:103021325]) HSP 1 Score: 124.79 bits (312), Expect = 1.213e-28 Identity = 114/475 (24.00%), Postives = 209/475 (44.00%), Query Frame = 2
Query: 1397 IEARLRCGACTKLLKEPRQTECGCRLCTECIIELTLNGPKQCPDCKETEIASLGETQEDRAASREIMNMRIKCPNKPCNWEGKIREASAHLNQCRYKRKPCEKCQQPISESEEKQHENV-CEERRTRCEYC--NITETWKQIQQEHVNVKEEKICDRFRGKCPNKCGVEE-EIELKEHWER-CSRKRIECPMAKWGCKIKILREETIQHVQETAEEHLKIWXXXXXXXXXXXXXX-------------------------XXEIESHK--ILMTEIFNTRESFELARIGM-SETEKNVENEMKR----LREHYQKLRSYTPTGENPPIAPYIWRIEEFTRKWQRARDGTEVSITSPPFYSWKNGYKLRMRVYPNGDGAGK-DTHVSVFFVLVKGEWDELQSWPFSNKMAFTIMSAKDA--HVERL--KPDGAPCYNKPTADVG-TAIGSPRIMRQNVMWE--YLEGDTLFVKWSV 2686
+E++ C C L+ QT CG R C CI + + ++CP + E+ + + D A REI+++ ++C N C + ++R H+ C++ PC +CQ+ + +SE ++H N C R C C NI KQ E++C F C +E +L H + C + + C + +GC+ K+LR + H+QE + H++ D ++N + E++ + +L E R+ +L + + +ET+ E+++ L E ++L++ G Y+WR+E F+ + G V + SPPFY+ + GYKL +R++ A + ++S+F ++GE+D SWP + ++ + HVE + KPD + +PT G M+ + + ++ D L V+ V
Sbjct: 64 LESKYECPICLMGLRSAVQTPCGHRFCNCCIRKSIRDTGQKCP--VDNEVLTEDQLFPDNFAKREILSLTVRCRNVGCMEKMELRHLENHIPHCKFATVPCPQCQESVWKSELEEHINQECSHRLITCPDCAENIIYAEKQFH--------EQLC-LFANTVCEYCNMELIRNQLASHCDTDCLKAPVACTFSIFGCREKMLRNDLALHMQEFTQMHMRYMADVLRNQTINGLISSHSASAASPTDSRGASSRPEGACQCNQELQQMRETVLELESRLVRQDHKLRELSIRNETQSTQMTELRKKLASLEESMRELQAQQYQGV------YVWRLEGFSTHIRNQEAGHPVVLHSPPFYTGRPGYKLCLRLHLQTPNAPRCSNYISLFVHTMQGEFDSQLSWPLQGTIRLAVLDQAEGQHHVEVMETKPD-LQAFQRPTVQRNPKGFGYVTFMQLQALHQRGFVRDDVLMVRCEV 520
BLAST of TNF receptor-associated factor vs. Ensembl Cavefish
Match: traf6 (TNF receptor associated factor 6 [Source:NCBI gene;Acc:103021325]) HSP 1 Score: 124.79 bits (312), Expect = 1.213e-28 Identity = 114/475 (24.00%), Postives = 209/475 (44.00%), Query Frame = 2
Query: 1397 IEARLRCGACTKLLKEPRQTECGCRLCTECIIELTLNGPKQCPDCKETEIASLGETQEDRAASREIMNMRIKCPNKPCNWEGKIREASAHLNQCRYKRKPCEKCQQPISESEEKQHENV-CEERRTRCEYC--NITETWKQIQQEHVNVKEEKICDRFRGKCPNKCGVEE-EIELKEHWER-CSRKRIECPMAKWGCKIKILREETIQHVQETAEEHLKIWXXXXXXXXXXXXXX-------------------------XXEIESHK--ILMTEIFNTRESFELARIGM-SETEKNVENEMKR----LREHYQKLRSYTPTGENPPIAPYIWRIEEFTRKWQRARDGTEVSITSPPFYSWKNGYKLRMRVYPNGDGAGK-DTHVSVFFVLVKGEWDELQSWPFSNKMAFTIMSAKDA--HVERL--KPDGAPCYNKPTADVG-TAIGSPRIMRQNVMWE--YLEGDTLFVKWSV 2686
+E++ C C L+ QT CG R C CI + + ++CP + E+ + + D A REI+++ ++C N C + ++R H+ C++ PC +CQ+ + +SE ++H N C R C C NI KQ E++C F C +E +L H + C + + C + +GC+ K+LR + H+QE + H++ D ++N + E++ + +L E R+ +L + + +ET+ E+++ L E ++L++ G Y+WR+E F+ + G V + SPPFY+ + GYKL +R++ A + ++S+F ++GE+D SWP + ++ + HVE + KPD + +PT G M+ + + ++ D L V+ V
Sbjct: 64 LESKYECPICLMGLRSAVQTPCGHRFCNCCIRKSIRDTGQKCP--VDNEVLTEDQLFPDNFAKREILSLTVRCRNVGCMEKMELRHLENHIPHCKFATVPCPQCQESVWKSELEEHINQECSHRLITCPDCAENIIYAEKQFH--------EQLC-LFANTVCEYCNMELIRNQLASHCDTDCLKAPVACTFSIFGCREKMLRNDLALHMQEFTQMHMRYMADVLRNQTINGLISSHSASAASPTDSRGASSRPEGACQCNQELQQMRETVLELESRLVRQDHKLRELSIRNETQSTQMTELRKKLASLEESMRELQAQQYQGV------YVWRLEGFSTHIRNQEAGHPVVLHSPPFYTGRPGYKLCLRLHLQTPNAPRCSNYISLFVHTMQGEFDSQLSWPLQGTIRLAVLDQAEGQHHVEVMETKPD-LQAFQRPTVQRNPKGFGYVTFMQLQALHQRGFVRDDVLMVRCEV 520
BLAST of TNF receptor-associated factor vs. Ensembl Cavefish
Match: traf2b (TNF receptor associated factor 2 [Source:NCBI gene;Acc:103028261]) HSP 1 Score: 123.635 bits (309), Expect = 3.161e-28 Identity = 76/251 (30.28%), Postives = 129/251 (51.39%), Query Frame = 2
Query: 1325 MEQQRTAIEVNEIIEIIRKQT-QIQIEARLRCGACTKLLKEPRQTECGCRLCTECIIELTLNGPKQCPDCK-------ETEIASLGETQEDRAASREIMNMRIKCPNKPCNWEGKIREASA-HLNQCRYKRKPCEKCQQPISESEEKQH-ENVCEERRTRCEYCNITETWKQIQQEHVNVKEEKICDRFRGKCPNKCGVEE--EIELKEHWERCSRKRIECPMAKWGCKIKILREETIQHVQETAEEHLKI 2041
M +Q V+ + I +Q + +E + +C C +L++P Q +CG R C C +LT +GP C C+ E + S+ E D AA REI + KCPN C+W G ++E H +C ++R CE CQ I S++ +H E CE R C+YC +T ++K I+ ++IC +F +C + CG ++ + EH + C++ + C ++ GC+ + + +H Q + EHL++
Sbjct: 11 MARQSLPSSVDSTLPGISRQVLSVSMEPKYQCQQCKGVLRKPFQAQCGHRFCVFCFKQLTSSGPIPCEACRAEGIFEMEHSMLSITEAFPDNAARREIDGLPAKCPNDGCSWNGTLKEYEVQHEGRCEFERVKCEACQMMILLSDKDRHNERECEARTLNCKYCKVTFSFKDIK------AHDEICQKFPMQCKD-CGKKKIPREKFAEHSKSCAKSKSACQFSEIGCRAVVDNGKQHEHEQSSIIEHLRL 254 HSP 2 Score: 110.923 bits (276), Expect = 4.106e-24 Identity = 49/143 (34.27%), Postives = 86/143 (60.14%), Query Frame = 2
Query: 2276 YIWRIEEFTRKWQRARDGTEVSITSPPFYSWKNGYKLRMRVYPNGDGAGKDTHVSVFFVLVKGEWDELQSWPFSNKMAFTIMSAKDAH--VERLKPD-GAPCYNKPTADVGTAIGSPR---IMRQNVMWEYLEGDTLFVKWSV 2686
++W+I +F+R+ Q A G ++ SP FYS K GYK+ +R+Y NGDG G+ +H+S+FFV+++G++D L WPFS K+ ++ + ++ +PD + + +P +++ A G P + + YL DT+F+K V
Sbjct: 384 FVWKISDFSRRRQDALAGRAPAMFSPAFYSSKYGYKMCLRLYLNGDGTGRGSHLSLFFVVMRGKYDALLKWPFSQKVTLMLLDQNNREHIIDAFRPDISSTSFQRPISEMNIASGCPLFCPLAKLAGKSSYLRDDTIFIKAIV 526
BLAST of TNF receptor-associated factor vs. Ensembl Sea Lamprey
Match: ENSPMAT00000000074.1 (pep scaffold:Pmarinus_7.0:GL482142:165593:173010:-1 gene:ENSPMAG00000000066.1 transcript:ENSPMAT00000000074.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 115.161 bits (287), Expect = 2.178e-26 Identity = 51/142 (35.92%), Postives = 85/142 (59.86%), Query Frame = 2
Query: 2279 IWRIEEFTRKWQRARDGTEVSITSPPFYSWKNGYKLRMRVYPNGDGAGKDTHVSVFFVLVKGEWDELQSWPFSNKMAFTIM---SAKDAHVERLKPD-GAPCYNKPTADVGTAIGSPRIMRQNVM--WEYLEGDTLFVKWSV 2686
+W+I ++ R+ Q A G +S+ S PFY+ GY++ R Y NGDG G+ TH+S+FFV+++GE+D L WPF ++ T++ +A+ + KPD + + +PT+D+ A G P + + YL+ DT+F+K V
Sbjct: 328 VWKIRDYARRKQDAVSGRTLSLYSQPFYTSPFGYRMCARAYLNGDGVGRGTHLSLFFVVMRGEYDALLPWPFRQRVTLTLLDQGAARRQLSDTFKPDPASSSFRRPTSDMNIASGCPLFVSHVALESASYLQDDTIFIKVVV 469 HSP 2 Score: 54.299 bits (129), Expect = 4.854e-7 Identity = 47/168 (27.98%), Postives = 72/168 (42.86%), Query Frame = 2
Query: 1571 DRAASREIMNMRIKCPNKPCNWE-----GKIREASAHLNQCRYKRKPC--EKCQQPISESEEKQHENV-CEERRTRCEYCNITETWKQIQQEHVNVKEEKICDRFRGKCPNKCGVEEEI---ELKEHWERCSRKRIECPMAKWGCKIKILREETIQHVQETAEEHLKI 2041
D REI+ +R+ C N + GK++E H+ C ++ C C + + E H + C R C YCN +Q+ E C R+ CPNKC E+ I EL H C K+ EC +++GCK K + +H ++HL +
Sbjct: 5 DNCCRREILALRVHCRNDTAGCKQIVELGKLQE---HMAVCVHEAVNCPHAGCTERLLRGELVNHVALGCHFRTESCRYCN-----QQVPLAEKRKHYETRCPRYPIPCPNKCE-EQSIAREELVSHLGICPYKQAECFFSQFGCKYKGTLQGLKEHESGATQQHLSL 163
BLAST of TNF receptor-associated factor vs. Ensembl Sea Lamprey
Match: ENSPMAT00000002130.1 (pep scaffold:Pmarinus_7.0:GL484662:8457:12718:-1 gene:ENSPMAG00000001936.1 transcript:ENSPMAT00000002130.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 106.686 bits (265), Expect = 5.508e-24 Identity = 50/142 (35.21%), Postives = 81/142 (57.04%), Query Frame = 2
Query: 2279 IWRIEEFTRKWQRARDGTEVSITSPPFYSWKNGYKLRMRVYPNGDGAGKDTHVSVFFVLVKGEWDELQSWPFSNKMAFTIM---SAKDAHVERLKPDGAP-CYNKPTADVGTAIGSPRIMRQNVM--WEYLEGDTLFVKWSV 2686
+W+I ++ R+ Q A G +S+ S PFY+ GYK+ R Y NGDG G+ TH+S+FFV+++GE+D L WPF ++ +++ +A+ + PD A + +P D+ A G P + + YL DT+FV+ V
Sbjct: 271 VWKIRDYARRKQEAASGRTLSLYSQPFYTSPFGYKMCARAYLNGDGVGRGTHLSLFFVVMRGEYDALLEWPFRRRVTLSLLDQGAARRHLSDTFTPDPASGSFRRPDGDMNVASGCPLFVSHVALEGSSYLVDDTVFVRVVV 412
BLAST of TNF receptor-associated factor vs. Ensembl Sea Lamprey
Match: ENSPMAT00000008091.1 (pep scaffold:Pmarinus_7.0:GL477915:34322:50582:-1 gene:ENSPMAG00000007312.1 transcript:ENSPMAT00000008091.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 98.9821 bits (245), Expect = 1.680e-21 Identity = 102/412 (24.76%), Postives = 173/412 (41.99%), Query Frame = 2
Query: 1403 ARLRCGACTKLLKEPRQTECGCRLCTECIIELTLNGPKQCPD-CKETEIASLGETQ--EDRAASREIMNMRIKCPNKPCNWEGKIREAS-AHLNQCRYKRKPCEKCQQPISESEEKQHENV---CEERRTRCEYCNITETWKQIQQEHVNVKEEKICDRFRGKCPNKCGVEEEIELK-EHWE--RCSRKRIECPMAKWGCKIKILREETIQHVQETAEEHLKIWXXXXXXXXXXXXXXXXEIESH------------------------KILMTEIFNTRESFELARIGMSETEKNVENEMKRLREHYQKLRSYTPTGENPPIAP---------YIWRIEEFTRKWQRARDGTE--VSITSPPFYSWKNGYKLRMRVYPNGDGAGKDTHVSVFFVLVKGEWDELQSWPFSNK 2503
AR CG+C LL++ QT CG R C CI L + + C D + TQ D A RE+ + ++C ++ C W G++ E AH+ +C + PC + + H +V C R C C ++Q+Q+ ++ C R + CG + E K +H E RC + R CP + GC + E H + + E HL I D K + +++ + H K + ++ + S I ET + ++N+M R+ EH + + G +A ++W+I+ + + A +G E I SP F++ + GY+LR+R+ +G+ HVS + +L G +D +WP+ K
Sbjct: 1 ARFACGSCQGLLRDAVQTHCGHRFCKPCIARLITSVHRSCNDTLMNSNFLVYSPTQFFPDAALRREMGVLPVRCVSEGCEWRGRLLEYDVAHVERCDWVLVPCLLAGCALLLPRAELHRHVAQECSVRPVPCAACAQLLPYRQLQKHQLH------CRSRRTRECKLCGQKSIPEDKWQHHEERRCMKNRDTCPYSPLGCLYRGHGESLHNHDKNSVEVHLAIVYDAFKKTFEQLIKGHADNIKHPPSARLVAAEAQLATMDRRVEEVAKRVERDVRVSEASTRQGNIDRDETAR-LQNKMARV-EHSDQETERSILGLTRRLAELENTAYNGMFLWKIKHVINRLREAGNGAERPPQIDSPAFFTTRYGYRLRLRLCRSGE------HVSAYAMLGPGPYDATLAWPYQLK 398
BLAST of TNF receptor-associated factor vs. Ensembl Sea Lamprey
Match: traf6 (TNF receptor-associated factor 6 [Source:NCBI gene;Acc:554561]) HSP 1 Score: 99.3673 bits (246), Expect = 6.015e-21 Identity = 63/224 (28.12%), Postives = 108/224 (48.21%), Query Frame = 2
Query: 1397 IEARLRCGACTKLLKEPRQTECGCRLCTECIIE---LTLNGPKQCPDCKETEIASLGETQEDRAASREIMNMRIKCPNKPCNWEGKIREASAHLNQCRYKRKPCEKCQQPISESEEKQH-ENVCEERRTRCEYCNITETWKQIQQEHVNVKEEKICDRFRGKCPNKCGVEEEI---ELKEHWE-RCSRKRIECPMAKWGCKIKILREETIQHVQETAEEHLKIW 2044
+E++ C C L+EP QT CG R C CI+ L GPK CP + + G+ D A REI+++ ++CPNKPC G++R H +C Y + PC +C+ P+ + +H E C R C +C +K + E++C C + ++E+ +L H E C + ++ C + GC+ +++R H+ E + H+++
Sbjct: 59 LESKYECPICLMALREPVQTPCGHRFCRACILHSMRLRDAGPK-CP--VDNAVLHEGQLFPDNFAKREILSLTVRCPNKPCGHRGELRALQEHQLRCEYAQVPCVRCEMPVCRRDLAKHEEQECMRRIVTCLHCCEKMAYKDSK------NHEQMCPLVVVNCKH---CQQELIREQLGPHLEVDCQQAQVPCTFSPLGCEAQMVRSLLAAHMHEHTQVHMRLL 270
BLAST of TNF receptor-associated factor vs. Ensembl Yeast
Match: RPL35A (Ribosomal 60S subunit protein L35A; homologous to mammalian ribosomal protein L35 and bacterial L29; RPL35A has a paralog, RPL35B, that arose from the whole genome duplication [Source:SGD;Acc:S000002350]) HSP 1 Score: 84.7297 bits (208), Expect = 1.953e-19 Identity = 52/122 (42.62%), Postives = 81/122 (66.39%), Query Frame = 2
Query: 80 MVKLRASELTKKNKADLEKQLHQLKTELAELRVAKVTGAGGTKLGKIRVLRKSIARVMTVMHTKQKDSLRQYYQHRKLKPQGIRTKATRAMRRQLTDNQKNKKTVRQIRLDRAWPEIIYAIK 445
M ++A EL K+K L QL LK ELAEL+V K++ L KI+ +RKSIA V+TV++ +Q++++RQ Y+ +K +P+ +R K TRA+RR LT + ++ T +Q + A+P+ YAIK
Sbjct: 1 MAGVKAYELRTKSKEQLASQLVDLKKELAELKVQKLSRPS---LPKIKTVRKSIACVLTVINEQQREAVRQLYKGKKYQPKDLRAKKTRALRRALTKFEASQVTEKQRKKQIAFPQRKYAIK 119
BLAST of TNF receptor-associated factor vs. Ensembl Yeast
Match: RPL35B (Ribosomal 60S subunit protein L35B; homologous to mammalian ribosomal protein L35 and bacterial L29; RPL35B has a paralog, RPL35A, that arose from the whole genome duplication [Source:SGD;Acc:S000002295]) HSP 1 Score: 84.7297 bits (208), Expect = 1.953e-19 Identity = 52/122 (42.62%), Postives = 81/122 (66.39%), Query Frame = 2
Query: 80 MVKLRASELTKKNKADLEKQLHQLKTELAELRVAKVTGAGGTKLGKIRVLRKSIARVMTVMHTKQKDSLRQYYQHRKLKPQGIRTKATRAMRRQLTDNQKNKKTVRQIRLDRAWPEIIYAIK 445
M ++A EL K+K L QL LK ELAEL+V K++ L KI+ +RKSIA V+TV++ +Q++++RQ Y+ +K +P+ +R K TRA+RR LT + ++ T +Q + A+P+ YAIK
Sbjct: 1 MAGVKAYELRTKSKEQLASQLVDLKKELAELKVQKLSRPS---LPKIKTVRKSIACVLTVINEQQREAVRQLYKGKKYQPKDLRAKKTRALRRALTKFEASQVTEKQRKKQIAFPQRKYAIK 119
BLAST of TNF receptor-associated factor vs. Ensembl Nematostella
Match: EDO38873 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SBN4]) HSP 1 Score: 159.073 bits (401), Expect = 9.628e-41 Identity = 128/478 (26.78%), Postives = 220/478 (46.03%), Query Frame = 2
Query: 1385 TQIQIEARLRCGACTKLLKEPRQTECGCRLCTECIIELTLNGPKQCPDCKETEIASLGETQEDRAASREIMNMRIKCPNKP--CNWEGKIREASAHLNQCRYKRKPC--EKCQQPISESEEKQH-ENVCEERRTRCEYCNITETWKQIQQEHVNVKEEKICDRFRGKCPNKCGVEEEIELKEHWERCSRK-RIECPMAKWGCK--IKIL--REETIQHVQE-------TAEEHLKIWXXXXXXXXXXXXXXXXEIES----HKILMTEIFNTRESF--ELARIGMSETEKNVENEMKRLREHYQKLRSYTPTGENPPIAP----------------YIWRIEEFTRKWQRARDGTEVSITSPPFYSWKNGYKLRMRVYPNGDGAGKDTHVSVFFVLVKGEWDELQSWPFSNKMAFTIMSAKDAH--VERLKPD-GAPCYNKPTADVGTAIGSPRI--MRQNVMWEYLEGDTLFVKWSV 2686
T I A+ C C ++K+ QT CG R C+ CI L GP QC C T + ET D+ A REI+ + + C N+P C WEG++R H +C + C +C + +S ++ +H +N C+ R C YC ++++ H EK C + CP KC +E I ++ H +R+ R+E GC+ +++L E I+ +++ + ++I + +++ +E+ H++L+ E + + E+ R+ + E +++ R E +L N IA +W+I K A G S SP F++ +GYK+ R+Y NGDG G++ HVS+FFV+++GE+D L WPF K+ ++ + ++ +PD + + +P A++ A G P Q Y+ DT+F+K V
Sbjct: 14 TDTAIAAKHLCAKCRLIVKDAVQTACGHRYCSPCISPLLSRGPIQCDVCGST--ITKPETFRDKFADREILELHVHCVNQPHGCPWEGELRHRQNHHTKCEFNPISCVHPECGKKLSVAKLPEHLQNECQYREETCSYCEQPVVVARMKEHH-----EKTCPSYPVNCP-KCS-KELIRVEVHSTPFTREPRLE---KGRGCENTLEVLEDHESRIKKLEQRGGGIGVNGLQSMRISENIDNEAIGDVLRRVANVEAKGADHEVLVVEAHSAVDELRREVGRLNVKLQES---DDIIRRLERQLELHDQGTGLRNLAIADLEERLNTLQGTTFDSVLLWKITNVANKRSEATSGRVTSFYSPCFFTGPHGYKMCARIYLNGDGMGRNHHVSLFFVIMRGEFDALLRWPFRQKVTLMLLDQDNVEHVIDAFRPDPSSSSFQRPRAEMNIASGCPLFCSHEQLTQHAYIRDDTMFLKIIV 476
BLAST of TNF receptor-associated factor vs. Ensembl Nematostella
Match: EDO41243 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S4Z7]) HSP 1 Score: 152.91 bits (385), Expect = 8.900e-39 Identity = 122/497 (24.55%), Postives = 210/497 (42.25%), Query Frame = 2
Query: 1391 IQIEARLRCGACTKLLKEPRQTECGCRLCTECIIELTLNGPK-QCPDCKETEIASLGETQEDRAASREIMNMRIKCPNKPCNWEGKIREASAHLNQCRYKRKPCEK--CQQPISESEEKQHENV-CEERRTRCEYCNITETWKQIQQEH----------------------VNVKEEKI----------------------------CDRFRGKCPNKCGVEEEIE-LKEHW-ERCSRKRIECPMAKWGCKIKILREETIQHVQETAEEHLKIWXXXXXXXXXXXXXXXXEIESHKILMTEIFNTRESFELARIGMSETEKNVENEMKRLREHYQKLRSYTPTGENPPIAPYIWRIEEFTRKWQRARDGTEVSITSPPFYSWKNGYKLRMRVYPNGDGAGKDTHVSVFFVLVKGEWDELQSWPFSNKMAFTIMSAKDAHVER------LKPD-GAPCYNKPTADVGTAIGSPRIMRQNVMW--EYLEGDTLFVKWSV 2686
I + C C L+ P QT+CG R C EC+ E + + +CP +E + + D+AA R I++ +KCP K C WE ++R+ AH C Y+ C C + + +H V C+ R CEYC E+ +Q+ H ++V E + CD+F CPN CG + E L++H E C + C +GC+++I QH+ + HL + +++L++ ++ F + G+ NE+ ++R ++WRI +F ++A+ G +V + S PF++ KNGYKLR +YPNG +GK+TH+S F + +GE+D + +WPF+ + T++ K+ ++R + P+ +++P GS + +W Y+ TLF++ V
Sbjct: 17 IAVAEEYTCRICHLPLRVPVQTKCGHRFCKECLDEASRRKSRAECPMDREP-LDLKKDVFLDKAAERTILSFLVKCPCKGCKWEAELRDLEAHARNCDYELVTCSNPMCSAQLPRMDVDEHLLVECDWRLIVCEYCG-DESPYCLQKAHARNCDYKLVTCSNPMCSAQLPRMDVDEHLLVECDWRLIVCEYCGDESPYCLQKDHSNQCDKFPVLCPNDCGTQITREKLRDHQSEECQFAVVPCAFRDFGCEVEIQNRLMDQHLDTNIQSHLNM-------------------TCNQLLLSR--DSGAQFHELQQGLGRV-----NELLKMR--------------------FVWRIPDFADSLRQAKLGLKVRLDSEPFFTEKNGYKLRATLYPNGTMSGKNTHISAFVSINRGEYDGILAWPFTRVIKITLLDQKENVLQRRNVEKTIIPNPSLENFHRPKTVSNNGRGSATFVSHEKLWTENYVVDGTLFMQVEV 465
BLAST of TNF receptor-associated factor vs. Ensembl Nematostella
Match: EDO32851 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7STV5]) HSP 1 Score: 147.902 bits (372), Expect = 3.174e-37 Identity = 128/458 (27.95%), Postives = 199/458 (43.45%), Query Frame = 2
Query: 1397 IEARLRCGACTKLLKEPRQTE-CGCRLCTECIIELTLNGPKQCPDCKETEIASLGETQEDRAASREIMNMRIKCPNK--PCNWEGKIREASAHLNQCRYKRKPCEK-CQQPISESEEKQH-ENVCEERRTRCEYCNITETWKQIQQEHVNVKEEKICDRFRGKCPNKCGVEEEI---ELKEHWER-CSRKRIECPMAKWGCKIKIL-------REETIQHVQETAEEHLKIWXXXXXXXXXXXXXXXXEIESHKILMTEIFNTRESFELARIGMSETEKNVENEMKRLREHYQKLRSYTPTGENPPIAPYIWRIEEFTRKWQRARDGTEVSITSPPFYSWKNGYKLRMRVYPNGDGAGKDTHVSVFFVLVKGEWDELQSWPFSNKMAFTIMSAKDAHVER------LKP----DGAPCYNKPTADVGTAIGSPRIMRQN--VMWEYLEGDTLFVKWSV 2686
++ + C C LL P Q + CG R+CT+C +L L+ +CP C + ++ + D+A EI + +KC N C WEG + E S+H+ +C Y CE C +H + C E+ C YC+ K + N C CPNKC + I EL H E C R ++ C GC +I RE+ +H + H+K+ D +++M+ ++ H L +E KRL + + S IWRIE++TRK + A+ G ++ SP F + K+GY+L V NGDG GK TH+SVF ++KG +D L WPF ++ F ++ D +R +KP D P +P + + G + + V Y++ DT+F+K SV
Sbjct: 39 LQKKYICLDCEGLLWYPVQIKPCGHRVCTKCYTKL-LSSSARCPGCMDELNENIPDI--DKAFHEEIQELDVKCRNVEWNCKWEGCVNEFSSHVEKCDYSDILCENDCGAKFQRRFLTKHLDKDCPEKLITCLYCDEKHLRKDKKGHLEN------CPLLPCPCPNKCDKKLTIHRCELDSHVENDCPRTKLMCEYEVLGCGHRITGLEGGGSREKMPKHNKTNIIAHVKMVADLALKNKELIMRFSEKLSEHGTL------------------------IEKHEKRLNDLEKIAHSQ-----------LIWRIEDYTRKMKEAKAGNTDTLFSPTFTTSKHGYRLCASVCLNGDGKGKGTHMSVFISVLKGAFDALLKWPFDYRVTFVLLDQNDDPAQRKHIRFSIKPNPCADNEPFLGRPRLEKNASFGGAKFAKHEEIVSRNYIKEDTIFLKISV 452
BLAST of TNF receptor-associated factor vs. Ensembl Nematostella
Match: EDO45915 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RRA4]) HSP 1 Score: 135.191 bits (339), Expect = 2.847e-33 Identity = 113/449 (25.17%), Postives = 197/449 (43.88%), Query Frame = 2
Query: 1391 IQIEARLRCGACTKLLKEPRQ-TECGCRLCTECIIELTLNGPKQCPDCKETEIASLGETQEDRAASREIMNMRIKCPN--KPCNWEGKIREASAHLNQ-CRYKRKPCEK-CQQPISESEEKQHENVCEERRTRCEYCNITETWKQIQQEHVNVKEEKICDRFRGKCPNKCGVEEEIE--LKEHW-ERCSRKRIECPMAKWGCKIKILREETIQHVQETAEEHLKIWXXXXXXXXXXXXXXXXEIESHKILMTEIFNTRESFELARIGMSETEKNVENEMKRLREHYQKLRSYTPTGENPPIAPYIWRIEEFTRKWQRARDG-TEVSITSPPFYSWKNGYKLRMRVYPNGDGAGKDTHVSVFFVLVKGEWDELQSWPFSNKMAFTIMS------AKDAHVERLKPDGAPCYNKPTADVGTAIGSPRIMRQNVM--WEYLEGDTLFVKWSV 2686
+ ++ C C L++P Q T CG R+C CI + N +CP + ++G+ D A R+I++M I CP+ C W+G I + HL + C C K C + + + H C R C +CN K++ +NV + C F CP CG ++ + L H + C I C A+ GC K R++ HVQE+ + SH ++ ++ + ++ +S ++ + + + ++ + RS GE +IW+I+ F+RK A+ G + S FY+ +GYK+ V+ NG G G+ ++SV + GE+D + WP + FT++ K V +P ++P+AD G+ R + Q+ + Y + +T+F+K+SV
Sbjct: 10 VPLDKSFECPVCLMALRDPVQVTPCGHRVCQTCIKPIIRNRRPRCP--LDNLTLNVGKIFPDNACHRQILSMDILCPHHGDGCEWQGTISDLEKHLERGCNLSEVRCPKDCGASVERGKLEGHYPECSRRLVNCTHCN-----KEVVFADMNVHLQS-CASFPISCPLTCGAKDLTKEALAVHLNQECPLLVIPCRFAEAGCTFKAKRQKMAAHVQES-------------------------LTSHVAMLCDLVCEQ------KLQISAQKERLLLQKEHIQLQIVECRSRCANGE------FIWKIQCFSRKLMDAKTGRASEPMISEAFYTSPHGYKMCAGVWLNGIGTGRGRYISVGLQVQSGEFDSILKWPLYPRYTFTLLDQSEDTKTKRDVVATFEPQS---ISRPSADRQLGKGARRFVLQDEVCGTTYCKDNTIFIKFSV 410
BLAST of TNF receptor-associated factor vs. Ensembl Nematostella
Match: EDO32849 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7STV3]) HSP 1 Score: 135.576 bits (340), Expect = 5.279e-33 Identity = 111/450 (24.67%), Postives = 196/450 (43.56%), Query Frame = 2
Query: 1400 EARLRCGACTKLLKEPRQT-ECGCRLCTECIIELTLNGPKQCPDCKETEIASLGETQEDRAASREIMNMRIKCPNK--PCNWEGKIREASAHLNQCRYKRKPCEK-CQQPISESEEKQH-ENVCEERRTRCEYCNITETWKQIQQEHVNVKEEKICDRFRGKCPNKCGVEEEI---ELKEHWER-CSRKRIECPMAKWGCKIKILREETIQHVQETAEEHLKIWXXXXXXXXXXXXXXXXEIESHKILMTEIFNTRESFELARIGMSETEKNVENEMKRLREHYQKLRSYTPTGENPPIAPYIWRIEEFTRKWQRARDGTEVSITSPPFYSWKNGYKLRMRVYPNGDGAGKDTHVSVFFVLVKGEWDELQSWPFSNKMAFTIMSAKDAHVERLK----------PDGAPCYNKPTADVGTAIGSPRIMRQNVM--WEYLEGDTLFVKWSV 2686
E + C C + P Q ECG RLC C + + +CP C + + D+A ++ + +C N C E + H +C Y C+ C +++H + C ++ C YC+ ++ ++EH+ + C CPNKC I +L EH E+ C R ++ C GC+ + RE+ +H++ H+K+ + + + + E H+ +M ++ +R+G + EK +++ IWRIE++TRK + A+ G ++ SP F + K+GY+L V NGDG GK TH+SVF ++KG +D L WPF ++ F +++ + ER PD P +P + + G + ++ + +++ DT+F+K SV
Sbjct: 50 ERKHLCPVCEDIFVSPVQIKECGHRLCQHCYKTIWRSPEPKCPKCSGDLDDKIPDV--DQAFENDMNELPCRCINHEWGCKVEVPFTQMITHKGECEYSDILCDNDCGAKFQRRFKQKHLDKDCPKKIISCPYCD-DRHLRENKKEHL-----EDCLLIPLPCPNKCDKTLTIPRGQLDEHIEKECPRAKLMCEFESLGCQHRCSREKMAKHMKSEIIGHVKMIFGVVLEQKEKLDNHAQKFEEHETIMKQV--------DSRVG--DLEKIAHSQI-------------------------IWRIEDYTRKLKEAKAGNAETLFSPTFTTSKHGYRLCASVCLNGDGKGKGTHMSVFVSVLKGAFDALLKWPFHYRVTFFLLNQHENPEERKHVKFSIKPNPIPDNEPFLGRPRLEKNASFGGAKFIKHEEIESGNFIKDDTVFLKVSV 456
BLAST of TNF receptor-associated factor vs. Ensembl Medaka
Match: traf3 (TNF receptor associated factor 3 [Source:NCBI gene;Acc:101161601]) HSP 1 Score: 155.221 bits (391), Expect = 2.323e-39 Identity = 124/448 (27.68%), Postives = 206/448 (45.98%), Query Frame = 2
Query: 1400 EARLRCGACTKLLKEPRQTECGCRLCTECIIELTLNGPKQCPDCKETEIASLGETQEDRAASREIMNMRIKCPNKP--CNWEGKIREASAHLNQCRYKRKPCE--KCQQPISESEEKQHEN-VCEERRTRCEYCNITETWKQIQQEHVNVKEEKICDRFRGKCPNKCGVEEEIELKEHWERCSRKRIECPMAKWGCKIKILREETIQHVQETAEEHLKIWXXXXXXXXXXXXXXXXEIESHKILMTEIFNTRESFELARIGMSETEKNVENEMKRLRE--------HYQKLRSYTPTGENPPIAPYIWRIEEFTRKWQRARDGTEVSITSPPFYSWKNGYKLRMRVYPNGDGAGKDTHVSVFFVLVKGEWDELQSWPFSNKMAFTIMSAKDA--HV-ERLKPD-GAPCYNKPTADVGTAIGSPRIMRQNVM--WEYLEGDTLFVKWSV 2686
EA+ C AC +L +PRQTECG R C CI ++ CP + E + D REIM +++ C ++ C + +++ H+N C + PC KC++ + E +H C+ R + CE+C ++Q+ +E +C F CPN H S R E K++ T + ++ E + Q++ E+ES + + + + E ET+ N ++M + E +Q L + + G IW+I ++ R+ Q A G +S+ S PFY+ GYK+ RVY NGDG GK TH+S+FFV+++GE+D L WPF K+ +M + H+ + KPD + + +P A++ A G P + Q+V+ Y++ DT+F+K +V
Sbjct: 43 EAKYCCEACRLVLCQPRQTECGHRFCYSCINDILSCPNPVCP--ADMEPLFKDKIFRDVCCHREIMALKVYCRSEANGCQEQMSLQQIPDHVNVCPFFEVPCPLGKCKERMMRKEIPEHLAWKCKYRESTCEFCKNKMPLTELQKH-----KETVCPAFPVSCPN------------HCTSSSLPRSE----------KLMSSHTEKLLELELELR-------------SLRQLRDEMESLRGTLDTVRTRLSALEQGGRASLETQLNRHDDMLSVHEIRLADMDLRFQVLETASYNGT------LIWKIRDYKRRKQDAVAGKTLSLYSQPFYTGYFGYKMCARVYLNGDGMGKGTHLSLFFVVMRGEYDALLPWPFKQKVTLMLMDQGPSRKHLGDAFKPDPSSSSFRRPVAEMNIASGCPLFVSQSVLESGTYIKDDTIFIKVTV 442
BLAST of TNF receptor-associated factor vs. Ensembl Medaka
Match: traf4a (TNF receptor associated factor 4 [Source:NCBI gene;Acc:101161428]) HSP 1 Score: 140.198 bits (352), Expect = 3.903e-34 Identity = 110/499 (22.04%), Postives = 203/499 (40.68%), Query Frame = 2
Query: 1406 RLRCGACTKLLKEPRQ-TECGCRLCTECIIELTLNGPKQCPDCKETEIASLGETQEDRAASREIMNMRIKCPN--KPCNWEGKIREASAHLNQCRYKRKPC-EKCQQPISESEEKQH-ENVCEERRTRCEYCNITETWKQIQQEHVNVKEEKI------------------------------------------------CDRFRGKCPNKCGVEEEI--ELKEHW-ERCSRKRIECPMAKWGCKIKILREETIQHVQETAEEHLKIWXXXXXXXXXXXXXXXXEIESHKILMTEIFNTRESFELARIGMSETEKNVENEMKRLREHYQKLRSYTPTGENPPIAPYIWRIEEFTRKWQRARDGTEVSITSPPFYSWKNGYKLRMRVYPNGDGAGKDTHVSVFFVLVKGEWDELQSWPFSNKMAFTIMSAKDAHV-------ERLKPDG------APCYNKPTADVGT-AIGSPRIMRQNVMWE--YLEGDTLFVKWSV 2686
R +C C+K ++EP Q + CG R C C+ E G +CP+ + + D ++I+++ I+C + + C W G++++ H + C + PC +C ++ + H ++ C +R+ +CE+C T + + +E + C RF +CPN+CG +L H + C + CP GCK + + +H+++T + HL + + + +E EL R EM+ L + + IW++ +++RK Q A+ + SPPFY+ + GYKL++ + NG+G+G+ +H+SV+ ++ GE+D L WPFS K+ F+I+ D + E PD PC + + D T G P+ + + + Y+ + +F+K S+
Sbjct: 15 RFQCPLCSKAMREPVQVSTCGHRFCDTCLQEFLSEGVFKCPE--DQLPLDYAKIYPDPELEQQILSLPIRCIHSEEGCRWTGQMKQLQGHFSTCAFNVIPCPNRCSVKLTRRDLPDHLQHDCPKRKVKCEFCGSEFTGEAFENHQGVCPQESVYCENKCGARMMRRLLSQHGMAECPKRTQPCKYCGKEFVFDTIQNHQFHCPRFPVQCPNQCGTPNIAREDLANHVKDNCGSALVLCPFKDAGCKHRCPKLAIGRHLEDTTKSHLTMMCNLVSR-----------------------QRQEILELRR------------EMEELSVSHDGV--------------LIWKLNDYSRKLQEAKLRSNHEFFSPPFYTHRYGYKLQVSAFLNGNGSGEGSHLSVYIRVLPGEYDNLLEWPFSYKVTFSILDQSDPSLSKPQHITETFNPDPNWKNFQKPCSTRNSLDESTLGFGYPKFISHEEIKKRNYIRDNCIFIKASI 462
BLAST of TNF receptor-associated factor vs. Ensembl Medaka
Match: traf4a (TNF receptor associated factor 4 [Source:NCBI gene;Acc:101161428]) HSP 1 Score: 140.584 bits (353), Expect = 5.409e-34 Identity = 110/499 (22.04%), Postives = 203/499 (40.68%), Query Frame = 2
Query: 1406 RLRCGACTKLLKEPRQ-TECGCRLCTECIIELTLNGPKQCPDCKETEIASLGETQEDRAASREIMNMRIKCPN--KPCNWEGKIREASAHLNQCRYKRKPC-EKCQQPISESEEKQH-ENVCEERRTRCEYCNITETWKQIQQEHVNVKEEKI------------------------------------------------CDRFRGKCPNKCGVEEEI--ELKEHW-ERCSRKRIECPMAKWGCKIKILREETIQHVQETAEEHLKIWXXXXXXXXXXXXXXXXEIESHKILMTEIFNTRESFELARIGMSETEKNVENEMKRLREHYQKLRSYTPTGENPPIAPYIWRIEEFTRKWQRARDGTEVSITSPPFYSWKNGYKLRMRVYPNGDGAGKDTHVSVFFVLVKGEWDELQSWPFSNKMAFTIMSAKDAHV-------ERLKPDG------APCYNKPTADVGT-AIGSPRIMRQNVMWE--YLEGDTLFVKWSV 2686
R +C C+K ++EP Q + CG R C C+ E G +CP+ + + D ++I+++ I+C + + C W G++++ H + C + PC +C ++ + H ++ C +R+ +CE+C T + + +E + C RF +CPN+CG +L H + C + CP GCK + + +H+++T + HL + + + +E EL R EM+ L + + IW++ +++RK Q A+ + SPPFY+ + GYKL++ + NG+G+G+ +H+SV+ ++ GE+D L WPFS K+ F+I+ D + E PD PC + + D T G P+ + + + Y+ + +F+K S+
Sbjct: 15 RFQCPLCSKAMREPVQVSTCGHRFCDTCLQEFLSEGVFKCPE--DQLPLDYAKIYPDPELEQQILSLPIRCIHSEEGCRWTGQMKQLQGHFSTCAFNVIPCPNRCSVKLTRRDLPDHLQHDCPKRKVKCEFCGSEFTGEAFENHQGVCPQESVYCENKCGARMMRRLLSQHGMAECPKRTQPCKYCGKEFVFDTIQNHQFHCPRFPVQCPNQCGTPNIAREDLANHVKDNCGSALVLCPFKDAGCKHRCPKLAIGRHLEDTTKSHLTMMCNLVSR-----------------------QRQEILELRR------------EMEELSVSHDGV--------------LIWKLNDYSRKLQEAKLRSNHEFFSPPFYTHRYGYKLQVSAFLNGNGSGEGSHLSVYIRVLPGEYDNLLEWPFSYKVTFSILDQSDPSLSKPQHITETFNPDPNWKNFQKPCSTRNSLDESTLGFGYPKFISHEEIKKRNYIRDNCIFIKASI 462
BLAST of TNF receptor-associated factor vs. Ensembl Medaka
Match: traf4a (TNF receptor associated factor 4 [Source:NCBI gene;Acc:101161428]) HSP 1 Score: 135.191 bits (339), Expect = 1.580e-32 Identity = 110/500 (22.00%), Postives = 203/500 (40.60%), Query Frame = 2
Query: 1406 RLRCGACTKLLKEPRQ-TECGCRLCTECIIE-LTLNGPKQCPDCKETEIASLGETQEDRAASREIMNMRIKCPN--KPCNWEGKIREASAHLNQCRYKRKPC-EKCQQPISESEEKQH-ENVCEERRTRCEYCNITETWKQIQQEHVNVKEEKI------------------------------------------------CDRFRGKCPNKCGVEEEI--ELKEHW-ERCSRKRIECPMAKWGCKIKILREETIQHVQETAEEHLKIWXXXXXXXXXXXXXXXXEIESHKILMTEIFNTRESFELARIGMSETEKNVENEMKRLREHYQKLRSYTPTGENPPIAPYIWRIEEFTRKWQRARDGTEVSITSPPFYSWKNGYKLRMRVYPNGDGAGKDTHVSVFFVLVKGEWDELQSWPFSNKMAFTIMSAKDAHV-------ERLKPDG------APCYNKPTADVGT-AIGSPRIMRQNVMWE--YLEGDTLFVKWSV 2686
R +C C+K ++EP Q + CG R C C+ E L++ P + L + D ++I+++ I+C + + C W G++++ H + C + PC +C ++ + H ++ C +R+ +CE+C T + + +E + C RF +CPN+CG +L H + C + CP GCK + + +H+++T + HL + + + +E EL R EM+ L + + IW++ +++RK Q A+ + SPPFY+ + GYKL++ + NG+G+G+ +H+SV+ ++ GE+D L WPFS K+ F+I+ D + E PD PC + + D T G P+ + + + Y+ + +F+K S+
Sbjct: 15 RFQCPLCSKAMREPVQVSTCGHRFCDTCLQEFLSIFFP----------MGLLPQIYPDPELEQQILSLPIRCIHSEEGCRWTGQMKQLQGHFSTCAFNVIPCPNRCSVKLTRRDLPDHLQHDCPKRKVKCEFCGSEFTGEAFENHQGVCPQESVYCENKCGARMMRRLLSQHGMAECPKRTQPCKYCGKEFVFDTIQNHQFHCPRFPVQCPNQCGTPNIAREDLANHVKDNCGSALVLCPFKDAGCKHRCPKLAIGRHLEDTTKSHLTMMCNLVSR-----------------------QRQEILELRR------------EMEELSVSHDGV--------------LIWKLNDYSRKLQEAKLRSNHEFFSPPFYTHRYGYKLQVSAFLNGNGSGEGSHLSVYIRVLPGEYDNLLEWPFSYKVTFSILDQSDPSLSKPQHITETFNPDPNWKNFQKPCSTRNSLDESTLGFGYPKFISHEEIKKRNYIRDNCIFIKASI 455
BLAST of TNF receptor-associated factor vs. Ensembl Medaka
Match: traf2b (TNF receptor associated factor 2 [Source:NCBI gene;Acc:101159764]) HSP 1 Score: 123.25 bits (308), Expect = 3.390e-28 Identity = 69/228 (30.26%), Postives = 123/228 (53.95%), Query Frame = 2
Query: 1391 IQIEARLRCGACTKLLKEPRQTECGCRLCTECIIELTLNGPKQCPDCKETE-------IASLGETQEDRAASREIMNMRIKCPNKPCNWEGKIREASA-HLNQCRYKRKPCEKCQQPISESEEKQHENV-CEERRTRCEYCNITETWKQIQQEHVNVKEEKICDRFRGKCPNKCGVEE--EIELKEHWERCSRKRIECPMAKWGCKIKILREETIQHVQETAEEHLKI 2041
+ +E + +C C ++L++P Q +CG R C C +LT +GPK C C++ E I + E D AA REI ++ +C N+ C+W G I+E A H +C +++ CE CQ + ++ +H + CEER C+YC +T +K I+ ++IC +F +C + CG ++ + +H + C++ + CP ++ GCK + + +H + EHL++
Sbjct: 29 VPMEDKYKCQQCLQVLRKPVQAQCGHRFCVHCFRQLTSSGPKPCQACRKEEIYEEPMSILNSSEAFPDNAAGREIASLPARCLNQGCDWTGSIKEYEAKHEGRCEFEQIQCEACQALVLRKDKDRHNDRECEERTLNCKYCKVTFNFKDIK------AHDEICQKFPLQCKD-CGKKKIPREKFNDHAKSCAKSKSACPFSEVGCKSVVENGKISEHEHSSTMEHLRL 249 HSP 2 Score: 106.686 bits (265), Expect = 9.387e-23 Identity = 48/143 (33.57%), Postives = 84/143 (58.74%), Query Frame = 2
Query: 2276 YIWRIEEFTRKWQRARDGTEVSITSPPFYSWKNGYKLRMRVYPNGDGAGKDTHVSVFFVLVKGEWDELQSWPFSNKMAFTIMSAKDAH--VERLKPD-GAPCYNKPTADVGTAIGSPR---IMRQNVMWEYLEGDTLFVKWSV 2686
++W+I +F+ + Q A G ++ SP FYS K GYK+ +R+Y NGDG G+ TH+S+FFV+++ ++D L WPFS K+ ++ + ++ +PD + + +P +++ A G P + + YL DT+F+K V
Sbjct: 376 FVWKITDFSHRRQEAVSGRAPAMFSPAFYSSKYGYKMCLRLYLNGDGTGRGTHLSLFFVVMRSKYDALLKWPFSQKVTLMLLDQNNREHIIDAFRPDITSTSFQRPVSEMNIASGCPLFCPLAKLAGKSPYLRDDTIFIKAIV 518
BLAST of TNF receptor-associated factor vs. Planmine SMEST
Match: SMESG000023758.1 (SMESG000023758.1) HSP 1 Score: 332.028 bits (850), Expect = 3.518e-90 Identity = 165/429 (38.46%), Postives = 258/429 (60.14%), Query Frame = 2
Query: 1397 IEARLRCGACTKLLKEPRQTECGCRLCTECIIELTLNGPKQCPDCKETEIASLGETQEDRAASREIMNMRIKCPNKPCNWEGKIREASAHLNQCRYKRKPCEKCQQPISESEEKQHENVCEERRTRCEYCNITETWKQIQQEHVNVKEEKICDRFRGKCPNKCGVEEEIELKEHWERCSRKRIECPMAKWGCKIKILREETIQHVQETAEEHLKIWXXXXXXXXXXXXXXXXEIESHKILMTEIFNTRESFELARIGMSETEKNVENEMKRLREHYQKLRSYTPTGENPPIAPYIWRIEEFTRKWQRARDGTEVSITSPPFYSWKNGYKLRMRVYPNGDGAGKDTHVSVFFVLVKGEWDELQSWPFSNKMAFTIMSAKDAHVERLKPDGAPCYNKPTADVGTAIGSPRIMRQNVMW--EYLEGDTLFVK 2677
I+ RL+C C +LL RQT+CGCR+CT+C IE+ +CP C ET T D+A ++EI N+ I+C K C W+G ++EA +H N+C Y CEKCQ +++ K+H VC +R +CE+C + + W +I+ EH N KEE+ICD + G C N C +++++LKEHW CS K ++CP+ C++++ E +H+ E + EH +I M T+ + + ++ E ++ K L+ EI +R++FE ++ + +E +M+++ ++L + + PP AP+IW+I EF K QRA+DGT+ + SPP YSWKNGYKL +R+YPNGDG TH+SVF + +G++DEL +WPF M T M ++ + ++ P +PT D TAIG+PR Q + +L D L+ K
Sbjct: 3600 IKERLKCCKCRELLIGARQTKCGCRICTDCTIEVIETQTIKCPGCDETMERDEDPTTMDKATNKEINNLLIQCQVKECEWKGLMKEAESHTNECEYNEILCEKCQTILTKKTMKEHHKVCIKREEKCEFCGVIDEWIKIEMEHRNPKEEQICDLYEGTCANNCDKKDKVKLKEHWNECSGKPVKCPLELLKCQVRLPITEMQKHMMENSIEHTEIMMKTIGMLAWEVKSLRTENDAQKALIREILESRKNFERSQGNTLKKMAEIEKKMQQMTNSLKELETNSSIARKPPTAPFIWKITEFAEKLQRAKDGTQRILDSPPIYSWKNGYKLGIRLYPNGDGNATGTHISVFIRVGRGDYDELLTWPFKQNMILT-MKGQEDYRNPIRTGNEPQMGRPTTDWNTAIGTPRFYPQQRLRGEGFLREDNLYKK 4027 HSP 2 Score: 75.0998 bits (183), Expect = 1.419e-12 Identity = 87/265 (32.83%), Postives = 135/265 (50.94%), Query Frame = 3
Query: 3783 SERKTNGVLKEAKIWKQKYQAAMKELKEFPEKRVPLDNLQMWEQLEEQKVETE--NSQA---------------RLRLQEKREEN----LRKFTTVKVNQLTKIQDQMRKLAEGKEQSDLQVEIEKSRLECTEQEIDKYKKMCEQRDLAIHRQKALRGSEKEVFETKARELQAEIERLEAREITSTLEREVEDLTEEVNQLLYMLDGEMNISQELRERINEIVNIPPIVWTSLIPIMSVPTNTMNMGEPTEQPQETIIDEGFVEV 4514
+E K + +EAK WK+ +Q A KE++ ++ + +++ ++WEQ+E QK E N Q RLR EK E + K + NQLT + Q ++L E + ++LQ E+ R +EI + + E + + +A + K+ +E + L+ EIE+L+A E T LE +VE+LTE L Y+LD E+ IS LRE IN + N PPI+ L+P+ PT + T+ P E DEGF E
Sbjct: 4752 TEIKEKAIKREAKKWKEHFQEAKKEIRLLLKRILNMEDWELWEQVEVQKATIEELNEQVQNLEFREKIRQGTIRRLRRHEKEYEQQFNEMYKRSAETRNQLTDEKRQNQQLNE--KITELQQEVNGHRGVAVFKEI-QLRHQHEVNEQLKEQVEAEIKTIKQGYEENEQNLRKEIEKLKALENTHRLEMQVEELTENTEYLAYLLDEEIQISNALREEINALQNRPPIL---LMPLY--PTEIL-----TQVPAEP--DEGFGET 5001 HSP 3 Score: 71.633 bits (174), Expect = 1.691e-11 Identity = 33/106 (31.13%), Postives = 63/106 (59.43%), Query Frame = 2
Query: 2384 LRMRVYPNGDGAGKDTHVSVFFVLVKGEWDELQSWPFSNKMAFTIMSAK---DAHVERLKPDG-APCYNKPTADVGTAIGSPR-IMRQNVMWEYLEGDTLFVKWSV 2686
+++RVYPNGDG GK ++SV+F+L +G +D WPF+ K+ +I + + H E+L D + KP + A G P+ ++++ + ++++ DT+++ V
Sbjct: 1 MKLRVYPNGDGVGKGKYLSVYFLLARGRYDGKLEWPFNRKVTISIAKPRKWEEQHSEKLGVDPRSMISQKPRSTENVAGGVPQFLLKKYITPQFVKDDTIYITIEV 106
BLAST of TNF receptor-associated factor vs. Planmine SMEST
Match: SMESG000010523.1 (SMESG000010523.1) HSP 1 Score: 327.791 bits (839), Expect = 4.833e-89 Identity = 163/432 (37.73%), Postives = 260/432 (60.19%), Query Frame = 2
Query: 1397 IEARLRCGACTKLLKEPRQTECGCRLCTECIIELTLNGPKQCPDCKETEIASLGETQEDRAASREIMNMRIKCPNKPCNWEGKIREASAHLNQCRYKRKPCEKCQQPISESEEKQHENVCEERRTRCEYCNITETWKQIQQEHVNVKEEKICDRFRGKCPNKCGVEEEIELKEHWERCSRKRIECPMAKWGCKIKILREETIQHVQETAEEHLKIWXXXXXXXXXXXXXXXXEIESHKILMTEIFNTRESFELARIGMSETEKNVENEMKRLREHYQKLRSYTPTGENPPIAPYIWRIEEFTRKWQRARDGTEVSITSPPFYSWKNGYKLRMRVYPNGDGAGKDTHVSVFFVLVKGEWDELQSWPFSNKMAFTIMSAKDAHVERLKPDGAPCYNKPTADVGTAIGSPRIMRQNVMW--EYLEGDTLFVKWSV 2686
I+ RL+C C +LL RQT+CGCR+CT+C IE+ +CP C ET T D+A ++EI N+ ++C K C W+G ++EA +H N+C Y CEKCQ I++ K+H +C +R +CE+C +T+ W +I+ EH N KEE+ICD + G C N C +++++LKEHW CS K ++CP+ + C+ ++ E +H+ E + EH +I M T+ + + ++ E ++ K ++ EI +R++FE ++ + +E +M+++ + ++L + P AP+IW+I EF K QRA+DGT+ + SPP YSW+NGYKL +R+YPNGDG TH+SVF + +G++DEL +WPF M T M ++ + ++ P +PT D TAIG+PR Q + +L D L++K V
Sbjct: 3791 IKERLKCCKCKELLIGARQTKCGCRICTDCTIEVIETQTIKCPGCDETFEEDEDPTTMDKATNKEINNLLVQCRVKECEWKGLMKEAESHTNECEYNEILCEKCQTIITKKTMKEHHKICIKREEKCEFCGVTDEWIKIEMEHRNPKEEQICDLYEGVCANNCDKKDKVKLKEHWNECSGKPVKCPLELFNCQTQLPMAEMQKHMMENSIEHTEIMMKTIGMLAWEVKSLRTENDAQKAIIREILESRKNFEKSQGDTLKKMVEMEKKMQQMTNNIKELETNNSITRKHPTAPFIWKITEFAEKLQRAKDGTQRILDSPPIYSWENGYKLGIRLYPNGDGNATGTHISVFIRVGRGDYDELLTWPFKQNMILT-MKGQEDYRNPIRTGNEPQMGRPTTDWNTAIGTPRFYPQQRLRGEGFLREDNLYIKLEV 4221 HSP 2 Score: 100.523 bits (249), Expect = 3.111e-20 Identity = 49/145 (33.79%), Postives = 86/145 (59.31%), Query Frame = 2
Query: 2267 IAPYIWRIEEFTRKWQRARDGTEVSITSPPFYSWKNGYKLRMRVYPNGDGAGKDTHVSVFFVLVKGEWDELQSWPFSNKMAFTIMSA---KDAHVERLKPD-GAPCYNKPTADVGTAIGSPR-IMRQNVMWEYLEGDTLFVKWSV 2686
+APY W+I + K + A + + ITS FY+ GY++++RVYPNGDG GK ++SV+F+L +G +D WPF+ K+ +I ++ H E+L D G+ KP + A G P+ ++++ V ++++ DT+++ V
Sbjct: 320 LAPYTWKIGGWAEKVKSAEEEKIIGITSHQFYTEIGGYRMKLRVYPNGDGVGKGKYLSVYFLLARGRYDGKLEWPFNRKVTISIAKPGKWEERHSEKLGMDPGSMISQKPKSTENVAGGVPQFLLKKYVTPQFVKDDTIYITIEV 464
BLAST of TNF receptor-associated factor vs. Planmine SMEST
Match: SMESG000010523.1 (SMESG000010523.1) HSP 1 Score: 327.791 bits (839), Expect = 4.926e-89 Identity = 163/432 (37.73%), Postives = 260/432 (60.19%), Query Frame = 2
Query: 1397 IEARLRCGACTKLLKEPRQTECGCRLCTECIIELTLNGPKQCPDCKETEIASLGETQEDRAASREIMNMRIKCPNKPCNWEGKIREASAHLNQCRYKRKPCEKCQQPISESEEKQHENVCEERRTRCEYCNITETWKQIQQEHVNVKEEKICDRFRGKCPNKCGVEEEIELKEHWERCSRKRIECPMAKWGCKIKILREETIQHVQETAEEHLKIWXXXXXXXXXXXXXXXXEIESHKILMTEIFNTRESFELARIGMSETEKNVENEMKRLREHYQKLRSYTPTGENPPIAPYIWRIEEFTRKWQRARDGTEVSITSPPFYSWKNGYKLRMRVYPNGDGAGKDTHVSVFFVLVKGEWDELQSWPFSNKMAFTIMSAKDAHVERLKPDGAPCYNKPTADVGTAIGSPRIMRQNVMW--EYLEGDTLFVKWSV 2686
I+ RL+C C +LL RQT+CGCR+CT+C IE+ +CP C ET T D+A ++EI N+ ++C K C W+G ++EA +H N+C Y CEKCQ I++ K+H +C +R +CE+C +T+ W +I+ EH N KEE+ICD + G C N C +++++LKEHW CS K ++CP+ + C+ ++ E +H+ E + EH +I M T+ + + ++ E ++ K ++ EI +R++FE ++ + +E +M+++ + ++L + P AP+IW+I EF K QRA+DGT+ + SPP YSW+NGYKL +R+YPNGDG TH+SVF + +G++DEL +WPF M T M ++ + ++ P +PT D TAIG+PR Q + +L D L++K V
Sbjct: 3747 IKERLKCCKCKELLIGARQTKCGCRICTDCTIEVIETQTIKCPGCDETFEEDEDPTTMDKATNKEINNLLVQCRVKECEWKGLMKEAESHTNECEYNEILCEKCQTIITKKTMKEHHKICIKREEKCEFCGVTDEWIKIEMEHRNPKEEQICDLYEGVCANNCDKKDKVKLKEHWNECSGKPVKCPLELFNCQTQLPMAEMQKHMMENSIEHTEIMMKTIGMLAWEVKSLRTENDAQKAIIREILESRKNFEKSQGDTLKKMVEMEKKMQQMTNNIKELETNNSITRKHPTAPFIWKITEFAEKLQRAKDGTQRILDSPPIYSWENGYKLGIRLYPNGDGNATGTHISVFIRVGRGDYDELLTWPFKQNMILT-MKGQEDYRNPIRTGNEPQMGRPTTDWNTAIGTPRFYPQQRLRGEGFLREDNLYIKLEV 4177 HSP 2 Score: 100.523 bits (249), Expect = 3.267e-20 Identity = 49/145 (33.79%), Postives = 86/145 (59.31%), Query Frame = 2
Query: 2267 IAPYIWRIEEFTRKWQRARDGTEVSITSPPFYSWKNGYKLRMRVYPNGDGAGKDTHVSVFFVLVKGEWDELQSWPFSNKMAFTIMSA---KDAHVERLKPD-GAPCYNKPTADVGTAIGSPR-IMRQNVMWEYLEGDTLFVKWSV 2686
+APY W+I + K + A + + ITS FY+ GY++++RVYPNGDG GK ++SV+F+L +G +D WPF+ K+ +I ++ H E+L D G+ KP + A G P+ ++++ V ++++ DT+++ V
Sbjct: 320 LAPYTWKIGGWAEKVKSAEEEKIIGITSHQFYTEIGGYRMKLRVYPNGDGVGKGKYLSVYFLLARGRYDGKLEWPFNRKVTISIAKPGKWEERHSEKLGMDPGSMISQKPKSTENVAGGVPQFLLKKYVTPQFVKDDTIYITIEV 464
BLAST of TNF receptor-associated factor vs. Planmine SMEST
Match: SMESG000010523.1 (SMESG000010523.1) HSP 1 Score: 327.791 bits (839), Expect = 4.957e-89 Identity = 163/432 (37.73%), Postives = 260/432 (60.19%), Query Frame = 2
Query: 1397 IEARLRCGACTKLLKEPRQTECGCRLCTECIIELTLNGPKQCPDCKETEIASLGETQEDRAASREIMNMRIKCPNKPCNWEGKIREASAHLNQCRYKRKPCEKCQQPISESEEKQHENVCEERRTRCEYCNITETWKQIQQEHVNVKEEKICDRFRGKCPNKCGVEEEIELKEHWERCSRKRIECPMAKWGCKIKILREETIQHVQETAEEHLKIWXXXXXXXXXXXXXXXXEIESHKILMTEIFNTRESFELARIGMSETEKNVENEMKRLREHYQKLRSYTPTGENPPIAPYIWRIEEFTRKWQRARDGTEVSITSPPFYSWKNGYKLRMRVYPNGDGAGKDTHVSVFFVLVKGEWDELQSWPFSNKMAFTIMSAKDAHVERLKPDGAPCYNKPTADVGTAIGSPRIMRQNVMW--EYLEGDTLFVKWSV 2686
I+ RL+C C +LL RQT+CGCR+CT+C IE+ +CP C ET T D+A ++EI N+ ++C K C W+G ++EA +H N+C Y CEKCQ I++ K+H +C +R +CE+C +T+ W +I+ EH N KEE+ICD + G C N C +++++LKEHW CS K ++CP+ + C+ ++ E +H+ E + EH +I M T+ + + ++ E ++ K ++ EI +R++FE ++ + +E +M+++ + ++L + P AP+IW+I EF K QRA+DGT+ + SPP YSW+NGYKL +R+YPNGDG TH+SVF + +G++DEL +WPF M T M ++ + ++ P +PT D TAIG+PR Q + +L D L++K V
Sbjct: 3793 IKERLKCCKCKELLIGARQTKCGCRICTDCTIEVIETQTIKCPGCDETFEEDEDPTTMDKATNKEINNLLVQCRVKECEWKGLMKEAESHTNECEYNEILCEKCQTIITKKTMKEHHKICIKREEKCEFCGVTDEWIKIEMEHRNPKEEQICDLYEGVCANNCDKKDKVKLKEHWNECSGKPVKCPLELFNCQTQLPMAEMQKHMMENSIEHTEIMMKTIGMLAWEVKSLRTENDAQKAIIREILESRKNFEKSQGDTLKKMVEMEKKMQQMTNNIKELETNNSITRKHPTAPFIWKITEFAEKLQRAKDGTQRILDSPPIYSWENGYKLGIRLYPNGDGNATGTHISVFIRVGRGDYDELLTWPFKQNMILT-MKGQEDYRNPIRTGNEPQMGRPTTDWNTAIGTPRFYPQQRLRGEGFLREDNLYIKLEV 4223 HSP 2 Score: 100.523 bits (249), Expect = 3.164e-20 Identity = 49/145 (33.79%), Postives = 86/145 (59.31%), Query Frame = 2
Query: 2267 IAPYIWRIEEFTRKWQRARDGTEVSITSPPFYSWKNGYKLRMRVYPNGDGAGKDTHVSVFFVLVKGEWDELQSWPFSNKMAFTIMSA---KDAHVERLKPD-GAPCYNKPTADVGTAIGSPR-IMRQNVMWEYLEGDTLFVKWSV 2686
+APY W+I + K + A + + ITS FY+ GY++++RVYPNGDG GK ++SV+F+L +G +D WPF+ K+ +I ++ H E+L D G+ KP + A G P+ ++++ V ++++ DT+++ V
Sbjct: 320 LAPYTWKIGGWAEKVKSAEEEKIIGITSHQFYTEIGGYRMKLRVYPNGDGVGKGKYLSVYFLLARGRYDGKLEWPFNRKVTISIAKPGKWEERHSEKLGMDPGSMISQKPKSTENVAGGVPQFLLKKYVTPQFVKDDTIYITIEV 464
BLAST of TNF receptor-associated factor vs. Planmine SMEST
Match: SMESG000010523.1 (SMESG000010523.1) HSP 1 Score: 327.791 bits (839), Expect = 4.961e-89 Identity = 163/432 (37.73%), Postives = 260/432 (60.19%), Query Frame = 2
Query: 1397 IEARLRCGACTKLLKEPRQTECGCRLCTECIIELTLNGPKQCPDCKETEIASLGETQEDRAASREIMNMRIKCPNKPCNWEGKIREASAHLNQCRYKRKPCEKCQQPISESEEKQHENVCEERRTRCEYCNITETWKQIQQEHVNVKEEKICDRFRGKCPNKCGVEEEIELKEHWERCSRKRIECPMAKWGCKIKILREETIQHVQETAEEHLKIWXXXXXXXXXXXXXXXXEIESHKILMTEIFNTRESFELARIGMSETEKNVENEMKRLREHYQKLRSYTPTGENPPIAPYIWRIEEFTRKWQRARDGTEVSITSPPFYSWKNGYKLRMRVYPNGDGAGKDTHVSVFFVLVKGEWDELQSWPFSNKMAFTIMSAKDAHVERLKPDGAPCYNKPTADVGTAIGSPRIMRQNVMW--EYLEGDTLFVKWSV 2686
I+ RL+C C +LL RQT+CGCR+CT+C IE+ +CP C ET T D+A ++EI N+ ++C K C W+G ++EA +H N+C Y CEKCQ I++ K+H +C +R +CE+C +T+ W +I+ EH N KEE+ICD + G C N C +++++LKEHW CS K ++CP+ + C+ ++ E +H+ E + EH +I M T+ + + ++ E ++ K ++ EI +R++FE ++ + +E +M+++ + ++L + P AP+IW+I EF K QRA+DGT+ + SPP YSW+NGYKL +R+YPNGDG TH+SVF + +G++DEL +WPF M T M ++ + ++ P +PT D TAIG+PR Q + +L D L++K V
Sbjct: 3798 IKERLKCCKCKELLIGARQTKCGCRICTDCTIEVIETQTIKCPGCDETFEEDEDPTTMDKATNKEINNLLVQCRVKECEWKGLMKEAESHTNECEYNEILCEKCQTIITKKTMKEHHKICIKREEKCEFCGVTDEWIKIEMEHRNPKEEQICDLYEGVCANNCDKKDKVKLKEHWNECSGKPVKCPLELFNCQTQLPMAEMQKHMMENSIEHTEIMMKTIGMLAWEVKSLRTENDAQKAIIREILESRKNFEKSQGDTLKKMVEMEKKMQQMTNNIKELETNNSITRKHPTAPFIWKITEFAEKLQRAKDGTQRILDSPPIYSWENGYKLGIRLYPNGDGNATGTHISVFIRVGRGDYDELLTWPFKQNMILT-MKGQEDYRNPIRTGNEPQMGRPTTDWNTAIGTPRFYPQQRLRGEGFLREDNLYIKLEV 4228 HSP 2 Score: 100.523 bits (249), Expect = 3.138e-20 Identity = 49/145 (33.79%), Postives = 86/145 (59.31%), Query Frame = 2
Query: 2267 IAPYIWRIEEFTRKWQRARDGTEVSITSPPFYSWKNGYKLRMRVYPNGDGAGKDTHVSVFFVLVKGEWDELQSWPFSNKMAFTIMSA---KDAHVERLKPD-GAPCYNKPTADVGTAIGSPR-IMRQNVMWEYLEGDTLFVKWSV 2686
+APY W+I + K + A + + ITS FY+ GY++++RVYPNGDG GK ++SV+F+L +G +D WPF+ K+ +I ++ H E+L D G+ KP + A G P+ ++++ V ++++ DT+++ V
Sbjct: 320 LAPYTWKIGGWAEKVKSAEEEKIIGITSHQFYTEIGGYRMKLRVYPNGDGVGKGKYLSVYFLLARGRYDGKLEWPFNRKVTISIAKPGKWEERHSEKLGMDPGSMISQKPKSTENVAGGVPQFLLKKYVTPQFVKDDTIYITIEV 464 The following BLAST results are available for this feature:
BLAST of TNF receptor-associated factor vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99) Total hits: 5
BLAST of TNF receptor-associated factor vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99) Total hits: 5
BLAST of TNF receptor-associated factor vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99) Total hits: 5
BLAST of TNF receptor-associated factor vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99) Total hits: 5
BLAST of TNF receptor-associated factor vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99) Total hits: 5
BLAST of TNF receptor-associated factor vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99) Total hits: 5
BLAST of TNF receptor-associated factor vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt) Total hits: 5
BLAST of TNF receptor-associated factor vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL) Total hits: 5
BLAST of TNF receptor-associated factor vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99) Total hits: 5
BLAST of TNF receptor-associated factor vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99) Total hits: 4
BLAST of TNF receptor-associated factor vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46) Total hits: 2
BLAST of TNF receptor-associated factor vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46) Total hits: 5
BLAST of TNF receptor-associated factor vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99) Total hits: 5
BLAST of TNF receptor-associated factor vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST) Total hits: 5
Analyses
This transcript is derived from or has results from the following analyses Sequences
The following sequences are available for this feature:
transcript sequence >SMED30013205 ID=SMED30013205|Name=TNF receptor-associated factor|organism=Schmidtea mediterranea sexual|type=transcript|length=11006bpback to top protein sequence of SMED30013205-orf-1 >SMED30013205-orf-1 ID=SMED30013205-orf-1|Name=SMED30013205-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=124bp MVKLRASELTKKNKADLEKQLHQLKTELAELRVAKVTGAGGTKLGKIRVLback to top protein sequence of SMED30013205-orf-2 >SMED30013205-orf-2 ID=SMED30013205-orf-2|Name=SMED30013205-orf-2|organism=Schmidtea mediterranea sexual|type=polypeptide|length=160bp MNPYPKISILLLVTLINKSNPNPQRIQETLESIQTIKSELTRMQEYFLRKback to top protein sequence of SMED30013205-orf-3 >SMED30013205-orf-3 ID=SMED30013205-orf-3|Name=SMED30013205-orf-3|organism=Schmidtea mediterranea sexual|type=polypeptide|length=552bp MNNKEITIEIINHLPVIKMMQIMGNEHQRAILIKNEEMGTMNKIKTETEKback to top protein sequence of SMED30013205-orf-4 >SMED30013205-orf-4 ID=SMED30013205-orf-4|Name=SMED30013205-orf-4|organism=Schmidtea mediterranea sexual|type=polypeptide|length=122bp MEQNYQTSTNNETVIEMWKRQYNALTKVVNTLQEQWTESQIALREALNTNback to top protein sequence of SMED30013205-orf-5 >SMED30013205-orf-5 ID=SMED30013205-orf-5|Name=SMED30013205-orf-5|organism=Schmidtea mediterranea sexual|type=polypeptide|length=306bp MTNNDNSTNSMRIPRLPPSIVAIRHKYEDLKIQHRDLQVKHERVKGTWAPback to top protein sequence of SMED30013205-orf-6 >SMED30013205-orf-6 ID=SMED30013205-orf-6|Name=SMED30013205-orf-6|organism=Schmidtea mediterranea sexual|type=polypeptide|length=464bp MEQQRTAIEVNEIIEIIRKQTQIQIEARLRCGACTKLLKEPRQTECGCRLback to top Annotated Terms
The following terms have been associated with this transcript:
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