zf-3CxxC domain-containing protein

Overview
Namezf-3CxxC domain-containing protein
Smed IDSMED30013183
Length (bp)930
Neoblast Clusters

Zeng et. al., 2018



▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)



Explore this single cell expression dataset with our NB Cluster Shiny App



 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of zf-3CxxC domain-containing protein (SMED30013183) t-SNE clustered cells

Violin plots show distribution of expression levels for zf-3CxxC domain-containing protein (SMED30013183) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of zf-3CxxC domain-containing protein (SMED30013183) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for zf-3CxxC domain-containing protein (SMED30013183) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
Sort Descending | Sort Ascending | Only Non-Zero Values | Tile/Chart | Reset

Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020



SMED30013183

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 8

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
intestinal phagocyteSMED30013183SMESG000066582.1 Contig1015GPL15192PMID:23079596
Forsthoefel et al., 2012		FACS sorted cell population asexual adult cDNA to DNA expression microarray evidence
intestinal phagocyteSMED30013183SMESG000033796.1 Contig1015GPL15192PMID:23079596
Forsthoefel et al., 2012		FACS sorted cell population asexual adult cDNA to DNA expression microarray evidence
pharynxSMED30013183SMESG000033796.1 dd_Smed_v4_4477_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
gutSMED30013183SMESG000033796.1 dd_Smed_v4_4477_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
epidermisSMED30013183SMESG000033796.1 dd_Smed_v4_4477_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
Smed sexual biotypeSMED30013183SMESG000033796.1 Contig39246newmark_estsPMID:29674431
Fincher et al., 2018		FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
Smed sexual biotypeSMED30013183SMESG000033796.1 Contig39246uc_Smed_v2PMID:29674431
Fincher et al., 2018		FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
epidermisSMED30013183SMESG000033796.1 dd_Smed_v4_4477_0_1dd_Smed_v4PMID:28292427
Wurtzel et al., 2017		whole organism asexual adult single-cell RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
[Close]
BLAST of zf-3CxxC domain-containing protein vs. Ensembl Human
Match: RTP3 (receptor transporter protein 3 [Source:HGNC Symbol;Acc:HGNC:15572])

HSP 1 Score: 47.7506 bits (112), Expect = 9.193e-6
Identity = 33/113 (29.20%), Postives = 53/113 (46.90%), Query Frame = 2 
Query:  335 RFMCSNCSNVWTTMFGAVTFCV---YEENGYVLSFKLLGQKCNKCTAENFQTPIWYAEEIERVLENV----------SRYILNTGMPVKSIKTGNPKGCHREDACQACQAKIC 634
            RF CS+CS  W +    V F +    E++   +  ++  Q+C KC    F+ P +  E I R+L+N+           R+ L   +P+  IK  + +G H  D C+AC    C
Sbjct:   52 RFQCSSCSRNWASAQVLVLFHMNWSEEKSRGQVKMRVFTQRCKKCPQPLFEDPEFTQENISRILKNLVFRILKKCYRGRFQLIEEVPM--IKDISLEGPHNSDNCEACLQGFC 162
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BLAST of zf-3CxxC domain-containing protein vs. Ensembl Mouse
Match: Rtp4 (receptor transporter protein 4 [Source:MGI Symbol;Acc:MGI:1915025])

HSP 1 Score: 46.9802 bits (110), Expect = 3.333e-6
Identity = 25/73 (34.25%), Postives = 37/73 (50.68%), Query Frame = 2 
Query:  335 RFMCSNCSNVWTTMFGAVTFCVYEE---NGYVLSFKLLGQKCNKCTAENFQTPIWYAEEIERVLENVSRYILN 544
            RF CS C   WT+    +   +Y +   +      ++ GQKC KC    F+TP +  E I+R+L N+  YIL 
Sbjct:   54 RFQCSRCCRSWTSAQVMILCHMYPDTLKSQGQARMRIFGQKCQKCFGCQFETPKFSTEIIKRILNNLVNYILQ 126
[Close]
BLAST of zf-3CxxC domain-containing protein vs. Ensembl Mouse
Match: Rtp4 (receptor transporter protein 4 [Source:MGI Symbol;Acc:MGI:1915025])

HSP 1 Score: 47.7506 bits (112), Expect = 6.827e-6
Identity = 33/107 (30.84%), Postives = 47/107 (43.93%), Query Frame = 2 
Query:  335 RFMCSNCSNVWTTMFGAVTFCVYEE---NGYVLSFKLLGQKCNKCTAENFQTPIWYAEEIERVLENVSRYILNTGMPVKSIK-TGNP--------KGCHREDACQAC 619
            RF CS C   WT+    +   +Y +   +      ++ GQKC KC    F+TP +  E I+R+L N+  YIL      + I  T N          G H    C+AC
Sbjct:   54 RFQCSRCCRSWTSAQVMILCHMYPDTLKSQGQARMRIFGQKCQKCFGCQFETPKFSTEIIKRILNNLVNYILQRYYGHRKIALTSNASLGEKVTLDGPHDTRNCEAC 160
[Close]
BLAST of zf-3CxxC domain-containing protein vs. Ensembl Mouse
Match: Rtp4 (receptor transporter protein 4 [Source:MGI Symbol;Acc:MGI:1915025])

HSP 1 Score: 47.7506 bits (112), Expect = 6.827e-6
Identity = 33/107 (30.84%), Postives = 47/107 (43.93%), Query Frame = 2 
Query:  335 RFMCSNCSNVWTTMFGAVTFCVYEE---NGYVLSFKLLGQKCNKCTAENFQTPIWYAEEIERVLENVSRYILNTGMPVKSIK-TGNP--------KGCHREDACQAC 619
            RF CS C   WT+    +   +Y +   +      ++ GQKC KC    F+TP +  E I+R+L N+  YIL      + I  T N          G H    C+AC
Sbjct:   54 RFQCSRCCRSWTSAQVMILCHMYPDTLKSQGQARMRIFGQKCQKCFGCQFETPKFSTEIIKRILNNLVNYILQRYYGHRKIALTSNASLGEKVTLDGPHDTRNCEAC 160
[Close]
BLAST of zf-3CxxC domain-containing protein vs. Ensembl Mouse
Match: Rtp4 (receptor transporter protein 4 [Source:MGI Symbol;Acc:MGI:1915025])

HSP 1 Score: 47.7506 bits (112), Expect = 6.827e-6
Identity = 33/107 (30.84%), Postives = 47/107 (43.93%), Query Frame = 2 
Query:  335 RFMCSNCSNVWTTMFGAVTFCVYEE---NGYVLSFKLLGQKCNKCTAENFQTPIWYAEEIERVLENVSRYILNTGMPVKSIK-TGNP--------KGCHREDACQAC 619
            RF CS C   WT+    +   +Y +   +      ++ GQKC KC    F+TP +  E I+R+L N+  YIL      + I  T N          G H    C+AC
Sbjct:   54 RFQCSRCCRSWTSAQVMILCHMYPDTLKSQGQARMRIFGQKCQKCFGCQFETPKFSTEIIKRILNNLVNYILQRYYGHRKIALTSNASLGEKVTLDGPHDTRNCEAC 160
[Close]
BLAST of zf-3CxxC domain-containing protein vs. TrEMBL
Match: A0A1I8I6Y7 (zf-3CxxC domain-containing protein OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig033475g1 PE=4 SV=1)

HSP 1 Score: 112.849 bits (281), Expect = 3.343e-25
Identity = 64/189 (33.86%), Postives = 97/189 (51.32%), Query Frame = 2 
Query:  182 LFLAQNLHIVWFGAFFEKFQKVSDSMAKAWSLIPFSNPASVILT---------LNESAKVRFMCSNCSNVWTTMFGAVTFCVYEEN----GYVLSFKLLGQKCNKCTAENFQTPIWYAEEIERVLENVSRYI--LNTGMPVK----SIKTGNPKGCHREDACQACQAKICKYSRSKFPSESADEIEEKP 691
            + L+Q + IVW   F + F + S     +W L P  +P  V  T           + AKVRF+C  C   WT+M G V F VY+++    GYV  FKL GQKC  C ++ ++  IWY EE+E+V+EN+   +  L  GMP        + G+PK  H    CQAC+ ++C+  + +       + ++KP
Sbjct:  141 MALSQQMEIVWHERFVDFFSRFS---FGSWHLFPVFDPPDVDNTGIPRNQWRYFKDQAKVRFICYKCQKAWTSMGGQVVFWVYKDDAKNEGYV-HFKLYGQKCTDCNSQYYEHAIWYQEEVEKVIENLYHQVGHLYYGMPAHRKRVDRRMGHPKKEHNSATCQACRDRVCRMGQLQKRKSHGQQQQKKP 325
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BLAST of zf-3CxxC domain-containing protein vs. TrEMBL
Match: A0A1I8I4K3 (zf-3CxxC domain-containing protein OS=Macrostomum lignano OX=282301 PE=4 SV=1)

HSP 1 Score: 111.694 bits (278), Expect = 1.095e-24
Identity = 62/171 (36.26%), Postives = 90/171 (52.63%), Query Frame = 2 
Query:  182 LFLAQNLHIVWFGAFFEKFQKVSDSMAKAWSLIPFSNPASVILT---------LNESAKVRFMCSNCSNVWTTMFGAVTFCVYEEN----GYVLSFKLLGQKCNKCTAENFQTPIWYAEEIERVLENVSRYI--LNTGMPVK----SIKTGNPKGCHREDACQACQAKICK 637
            + L+Q + IVW   F + F + S     +W L P  +P  V  T           + AKVRF+C  C   WT+M G V F VY+++    GYV  FKL GQKC  C ++ ++  IWY EE+E+V+EN+   +  L  GMP        + G+PK  H    CQAC+ ++C+
Sbjct:  142 MALSQQMEIVWHERFVDFFSRFS---FGSWHLFPVFDPPDVDNTGIPRNQWRYFKDQAKVRFICYKCQKAWTSMGGQVVFWVYKDDAKNEGYV-HFKLYGQKCTDCNSQYYEHAIWYQEEVEKVIENLYHQVGHLYYGMPAHRKRVDRRMGHPKKEHNSATCQACRDRVCR 308
[Close]
BLAST of zf-3CxxC domain-containing protein vs. TrEMBL
Match: A0A1S3K363 (receptor-transporting protein 1-like isoform X1 OS=Lingula unguis OX=7574 GN=LOC106178173 PE=4 SV=1)

HSP 1 Score: 104.375 bits (259), Expect = 9.756e-23
Identity = 64/183 (34.97%), Postives = 91/183 (49.73%), Query Frame = 2 
Query:  131 HFYAQIYAKKRYENDSQLFL---AQNLHIVWFGAFFEKFQKVSDSMAKAWSLIP-FSNPASVILTLNESAKVRFMCSNCSNVWTTMFGAVTFC----VYEENGYVLSFKLLGQKCNKCTAENFQTPIWYAEEIERVLENVSRYILNT-----GMPVK-SIKTGNPKGCHREDACQACQAKICK 637
            H Y QI  K     D +  +   A  + IVW G F   F   +      W L+P FS P+       +SAKVRF C  C + WT+M G V F     V   +GYVL FKL GQ+CN+C +E F+  +WY EE+ +V+ NV   +          P++   + G P+  H  + CQAC+  +C+
Sbjct:   58 HVYGQITEKSSKAGDPRAHIKPGAVGMEIVWHGEFDRLF---AQYFPHQWFLMPTFSPPSERWRVFKDSAKVRFQCQECGHGWTSMKGRVVFWFHLNVATNSGYVL-FKLYGQQCNRCKSEKFEHAMWYPEEVIKVVGNVYNRVGQVYYGFYRPPLRIDRRPGKPRNQHNAELCQACKDGLCR 236
[Close]
BLAST of zf-3CxxC domain-containing protein vs. TrEMBL
Match: A0A0B7AP26 (zf-3CxxC domain-containing protein OS=Arion vulgaris OX=1028688 GN=ORF133593 PE=4 SV=1)

HSP 1 Score: 102.064 bits (253), Expect = 2.406e-22
Identity = 60/168 (35.71%), Postives = 87/168 (51.79%), Query Frame = 2 
Query:  167 ENDSQLFLAQNLHIVWFGAFFEKFQKVSDSMAKAWSLIP-FSNPASVILTLNESAKVRFMCSNCSNVWTTMFGAVTFCVY----EENGYVLSFKLLGQKCNKCTAENFQTPIWYAEEIERVLEN----VSRYILNTGMPVKSI--KTGNPKGCHREDACQACQAKICK 637
            E++  LFL+Q + +VW G F   F   +     AW L+P F  P+       +SAKVRF C  C + WT+M G V F  +      +GYV+ FKL GQ+C KC   +++  +WY EE+ +V+ N    V +       P   I  + G P+  H  D CQAC+  +CK
Sbjct:   31 ESELGLFLSQRMELVWHGEFDRLF---AQYYPHAWYLVPTFYPPSDRWRVFKDSAKVRFSCQECGHGWTSMKGRVIFWFHLNYTTNSGYVM-FKLYGQQCQKCKNGSYEHAMWYPEEVVKVIGNVYNRVGQIFYGFVRPPLRIDRRQGKPRNQHNADLCQACKEGLCK 194
[Close]
BLAST of zf-3CxxC domain-containing protein vs. TrEMBL
Match: A0A2L2YD70 (Putative receptor-transporting protein (Fragment) OS=Parasteatoda tepidariorum OX=114398 PE=2 SV=1)

HSP 1 Score: 99.3673 bits (246), Expect = 1.120e-21
Identity = 55/161 (34.16%), Postives = 85/161 (52.80%), Query Frame = 2 
Query:  197 NLHIVW---FGAFFEKFQKVSDSMAKAWSLIPF-SNPASVILTLNESAKVRFMCSNCSNVWTTMFGAVTF-CVYEENGYVLSFKLLGQKCNKCTAENFQTPIWYAEEIERVLENVSRYILNT--GMPVKSI----KTGNPKGCHREDACQACQAKICKYSR 646
            N+ ++W   F   F +F   S      W L+P  S P+    T  +SAKVRF C  C + WT+M G +TF C +  N  V++++L GQ+C+ C  + ++  +WY EEIE+VL N+   + +   G+    I    + G PK  H  + CQAC+  +C   R
Sbjct:   13 NVALIWQLIFNKLFSRFAPHS------WRLVPVTSKPSGRWHTFVDSAKVRFACEACGHGWTSMKGRITFWCAFSNNTGVVAYRLYGQQCDSCKGDGYEPAMWYPEEIEKVLLNIFSRVAHVFYGLERPPIQLNRRPGKPKNPHNSERCQACKDGVCAERR 167
[Close]
BLAST of zf-3CxxC domain-containing protein vs. Planmine SMEST
Match: SMESG000033796.1 (SMESG000033796.1)

HSP 1 Score: 500.36 bits (1287), Expect = 0.000e+0
Identity = 239/240 (99.58%), Postives = 240/240 (100.00%), Query Frame = 2 
Query:   98 KMGICVCAECVHFYAQIYAKKRYENDSQLFLAQNLHIVWFGAFFEKFQKVSDSMAKAWSLIPFSNPASVILTLNESAKVRFMCSNCSNVWTTMFGAVTFCVYEENGYVLSFKLLGQKCNKCTAENFQTPIWYAEEIERVLENVSRYILNTGMPVKSIKTGNPKGCHREDACQACQAKICKYSRSKFPSESADEIEEKPQTSDYESETEILWSIDNSVFKRSLSMPAKPEPINHPIFFSET 817
            +MGICVCAECVHFYAQIYAKKRYENDSQLFLAQNLHIVWFGAFFEKFQKVSDSMAKAWSLIPFSNPASVILTLNESAKVRFMCSNCSNVWTTMFGAVTFCVYEENGYVLSFKLLGQKCNKCTAENFQTPIWYAEEIERVLENVSRYILNTGMPVKSIKTGNPKGCHREDACQACQAKICKYSRSKFPSESADEIEEKPQTSDYESETEILWSIDNSVFKRSLSMPAKPEPINHPIFFSET
Sbjct:   38 QMGICVCAECVHFYAQIYAKKRYENDSQLFLAQNLHIVWFGAFFEKFQKVSDSMAKAWSLIPFSNPASVILTLNESAKVRFMCSNCSNVWTTMFGAVTFCVYEENGYVLSFKLLGQKCNKCTAENFQTPIWYAEEIERVLENVSRYILNTGMPVKSIKTGNPKGCHREDACQACQAKICKYSRSKFPSESADEIEEKPQTSDYESETEILWSIDNSVFKRSLSMPAKPEPINHPIFFSET 277
[Close]
BLAST of zf-3CxxC domain-containing protein vs. Planmine SMEST
Match: SMESG000033796.1 (SMESG000033796.1)

HSP 1 Score: 499.204 bits (1284), Expect = 0.000e+0
Identity = 239/239 (100.00%), Postives = 239/239 (100.00%), Query Frame = 2 
Query:  101 MGICVCAECVHFYAQIYAKKRYENDSQLFLAQNLHIVWFGAFFEKFQKVSDSMAKAWSLIPFSNPASVILTLNESAKVRFMCSNCSNVWTTMFGAVTFCVYEENGYVLSFKLLGQKCNKCTAENFQTPIWYAEEIERVLENVSRYILNTGMPVKSIKTGNPKGCHREDACQACQAKICKYSRSKFPSESADEIEEKPQTSDYESETEILWSIDNSVFKRSLSMPAKPEPINHPIFFSET 817
            MGICVCAECVHFYAQIYAKKRYENDSQLFLAQNLHIVWFGAFFEKFQKVSDSMAKAWSLIPFSNPASVILTLNESAKVRFMCSNCSNVWTTMFGAVTFCVYEENGYVLSFKLLGQKCNKCTAENFQTPIWYAEEIERVLENVSRYILNTGMPVKSIKTGNPKGCHREDACQACQAKICKYSRSKFPSESADEIEEKPQTSDYESETEILWSIDNSVFKRSLSMPAKPEPINHPIFFSET
Sbjct:    1 MGICVCAECVHFYAQIYAKKRYENDSQLFLAQNLHIVWFGAFFEKFQKVSDSMAKAWSLIPFSNPASVILTLNESAKVRFMCSNCSNVWTTMFGAVTFCVYEENGYVLSFKLLGQKCNKCTAENFQTPIWYAEEIERVLENVSRYILNTGMPVKSIKTGNPKGCHREDACQACQAKICKYSRSKFPSESADEIEEKPQTSDYESETEILWSIDNSVFKRSLSMPAKPEPINHPIFFSET 239
The following BLAST results are available for this feature:
BLAST of zf-3CxxC domain-containing protein vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 1
Match NameE-valueIdentityDescription
RTP39.193e-629.20receptor transporter protein 3 [Source:HGNC Symbol... [more]
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BLAST of zf-3CxxC domain-containing protein vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of zf-3CxxC domain-containing protein vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of zf-3CxxC domain-containing protein vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of zf-3CxxC domain-containing protein vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of zf-3CxxC domain-containing protein vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 4
Match NameE-valueIdentityDescription
Rtp43.333e-634.25receptor transporter protein 4 [Source:MGI Symbol;... [more]
Rtp46.827e-630.84receptor transporter protein 4 [Source:MGI Symbol;... [more]
Rtp46.827e-630.84receptor transporter protein 4 [Source:MGI Symbol;... [more]
Rtp46.827e-630.84receptor transporter protein 4 [Source:MGI Symbol;... [more]
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BLAST of zf-3CxxC domain-containing protein vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of zf-3CxxC domain-containing protein vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
A0A1I8I6Y73.343e-2533.86zf-3CxxC domain-containing protein OS=Macrostomum ... [more]
A0A1I8I4K31.095e-2436.26zf-3CxxC domain-containing protein OS=Macrostomum ... [more]
A0A1S3K3639.756e-2334.97receptor-transporting protein 1-like isoform X1 OS... [more]
A0A0B7AP262.406e-2235.71zf-3CxxC domain-containing protein OS=Arion vulgar... [more]
A0A2L2YD701.120e-2134.16Putative receptor-transporting protein (Fragment) ... [more]
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BLAST of zf-3CxxC domain-containing protein vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of zf-3CxxC domain-containing protein vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of zf-3CxxC domain-containing protein vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of zf-3CxxC domain-containing protein vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of zf-3CxxC domain-containing protein vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of zf-3CxxC domain-containing protein vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 2
Match NameE-valueIdentityDescription
SMESG000033796.10.000e+099.58SMESG000033796.1[more]
SMESG000033796.10.000e+0100.00SMESG000033796.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30013183 ID=SMED30013183|Name=zf-3CxxC domain-containing protein|organism=Schmidtea mediterranea sexual|type=transcript|length=930bp
AAAATTATTATTTCCCGGATTTATAATTTATCAATTTCAGTTAAATTACT
TTAAAATTTGCAGATATATAACAAAGAAAAGAAGTTTCTAAAAATAGAAG
ATGGGTATTTGCGTCTGCGCAGAATGCGTACATTTTTACGCACAGATTTA
TGCAAAAAAAAGATATGAAAATGACTCTCAATTGTTCCTTGCACAAAATT
TACACATCGTTTGGTTTGGAGCGTTCTTTGAAAAATTTCAGAAAGTCAGC
GATTCAATGGCGAAAGCCTGGAGTTTGATTCCGTTCTCGAATCCGGCATC
GGTTATTTTGACTTTGAACGAGTCTGCAAAAGTTAGATTTATGTGTTCGA
ATTGCTCCAATGTTTGGACAACAATGTTCGGCGCGGTAACGTTTTGTGTA
TATGAAGAAAATGGGTATGTGTTGTCGTTTAAGCTACTCGGACAGAAATG
TAACAAATGTACCGCAGAGAATTTCCAAACTCCAATTTGGTATGCGGAAG
AAATCGAAAGGGTTTTGGAAAACGTTTCGAGGTACATATTAAATACCGGA
ATGCCGGTAAAGTCAATTAAAACCGGAAATCCGAAAGGCTGTCACAGAGA
AGATGCTTGTCAAGCATGTCAAGCGAAAATCTGCAAATATTCTAGGTCAA
AATTTCCATCGGAATCAGCGGATGAGATAGAAGAAAAACCCCAGACATCA
GATTATGAATCGGAAACAGAAATTCTATGGAGTATTGACAATTCGGTTTT
TAAGAGGAGTTTATCCATGCCTGCTAAACCAGAACCGATAAACCATCCGA
TATTTTTTTCGGAAACATGACGATATCGTTTGGTGTTATGTACAGAGAAT
AAATGTATATTTGTAATTTGAGGCTTGAAAATAGTTTTTAATGAAATTTT
CAATTTTTTATATTTGAGCCGTTATAAATG
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protein sequence of SMED30013183-orf-1

>SMED30013183-orf-1 ID=SMED30013183-orf-1|Name=SMED30013183-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=240bp
MGICVCAECVHFYAQIYAKKRYENDSQLFLAQNLHIVWFGAFFEKFQKVS
DSMAKAWSLIPFSNPASVILTLNESAKVRFMCSNCSNVWTTMFGAVTFCV
YEENGYVLSFKLLGQKCNKCTAENFQTPIWYAEEIERVLENVSRYILNTG
MPVKSIKTGNPKGCHREDACQACQAKICKYSRSKFPSESADEIEEKPQTS
DYESETEILWSIDNSVFKRSLSMPAKPEPINHPIFFSET*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000016pharynx
PLANA:0000034epidermis
PLANA:0000070intestinal phagocyte
PLANA:0002032epidermal cell
Vocabulary: INTERPRO
TermDefinition
IPR026096R-trans_p
IPR027377Znf-3CxxC
Vocabulary: biological process
TermDefinition
GO:0001580detection of chemical stimulus involved in sensory perception of bitter taste
GO:0006612protein targeting to membrane
GO:0051205protein insertion into membrane
Vocabulary: cellular component
TermDefinition
GO:0005737cytoplasm
GO:0009986cell surface
GO:0016020membrane
GO:0016021integral component of membrane
Vocabulary: molecular function
TermDefinition
GO:0031849olfactory receptor binding
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR027377Zinc-binding domainSMARTSM01328zf_3CxxC_2coord: 75..176
e-value: 1.4E-18
score: 77.7
IPR027377Zinc-binding domainPFAMPF13695zf-3CxxCcoord: 76..175
e-value: 1.6E-20
score: 73.4
IPR026096Receptor-transporting proteinPANTHERPTHR14402RECEPTOR TRANSPORTING PROTEINcoord: 27..183
NoneNo IPR availablePANTHERPTHR14402:SF10coord: 27..183