Rho GTPase-activating protein
|
Overview
Neoblast Clusters
Zeng et. al., 2018▻ Overview▻ Neoblast Population▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Overview
Single cell RNA-seq of pluripotent neoblasts and its early progeniesWe isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)Explore this single cell expression dataset with our NB Cluster Shiny App
Neoblast Population
Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Embryonic Expression
Davies et. al., 2017
Hover the mouse over a column in the graph to view average RPKM values per sample. Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult. back to top Anatomical Expression
PAGE et. al., 2020SMED30013182 has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGEPAGE Curations: 6
Homology
BLAST of Rho GTPase-activating protein vs. Ensembl Human
Match: SYDE2 (synapse defective Rho GTPase homolog 2 [Source:HGNC Symbol;Acc:HGNC:25841]) HSP 1 Score: 211.46 bits (537), Expect = 1.072e-54 Identity = 124/370 (33.51%), Postives = 203/370 (54.86%), Query Frame = 1
Query: 2671 YVSGMLVIHVVAGIGLNSSQTVVRDLYCVLEIDSVRRARSMIRTS-TEIFEWDEIFELDVEDNDWLAFLFYQWDPRNR-HRLCFYGNVALRQLIERFRHSYTNSEKLALYLEPKGVLFIELLYLKINEVFQRFKMPVNTDAL-FGVPLEVLVSRDLNRQGETDGQECRVPIIVRRCTEEVEKRGLDVVSIYRLSGAVKLKIRIREMLEQDVIAADLSADTVPDIHAITAVLRDFLRELPEPLFTNALYRMILDALQVSL-----------PGDNYAGAKLMLNILDCLPIVNQDTILHLLDHLKRVSSRSEVNKMTNEALAASLGPVLFFPSPEEAXXXXXXXXXXXXQA---------QTLLYILNIWP 3711
Y+SG++ +H L + +D++C +++DSV +AR+ + T T + D F +++E+ L + + W+P R +R+C +G V L L FR T + +LA+ LEP+G++++++ ++ E + +N + + FGV ++ +V E + VP+++++C E+EKRG VV +YRL G+ +K +RE E+D A L + PDI+ IT VL+D+LRELP PL T LY +LDA+ S PGD +K +++LDCLP + + T+ LLDHLK V+S EVNKMT + LA GPVL E + ++ D ++ A + L Y+L +WP
Sbjct: 677 YISGLMSVHFYGAEDLKPPRIDSKDVFCAIQVDSVNKARTALLTCRTTFLDMDHTFNIEIENAQHLKLVVFSWEPTPRKNRVCCHGTVVLPTL---FR--VTKTHQLAVKLEPRGLIYVKVTLMEQWE-NSLHGLDINQEPIIFGVDIQKVV--------EKENIGLMVPLLIQKCIMEIEKRGCQVVGLYRLCGSAAVKKELREAFERDSKAVGLCENQYPDINVITGVLKDYLRELPSPLITKQLYEAVLDAMAKSPLKMSSNGCENDPGD----SKYTVDLLDCLPEIEKATLKMLLDHLKLVASYHEVNKMTCQNLAVCFGPVLLSQRQEPSTHNNRVFTDSEELASALDFKKHIEVLHYLLQLWP 1028
BLAST of Rho GTPase-activating protein vs. Ensembl Human
Match: SYDE1 (synapse defective Rho GTPase homolog 1 [Source:HGNC Symbol;Acc:HGNC:25824]) HSP 1 Score: 183.726 bits (465), Expect = 4.331e-47 Identity = 127/356 (35.67%), Postives = 186/356 (52.25%), Query Frame = 1
Query: 2680 GMLVIHVVAGIGLNSSQTVV-RDLYCVLEIDSVRRARSM-IRTSTEIFEWDEIFELDVEDNDWLAFLFYQWDPR-NRHRLCFYGNVALRQLIERFRHSYTNSEKLALYLEPKGVLFIELLYLKINEVFQRFKMPVNTDA-LFGVPLEVLVSRDLNRQGETDGQECRVPIIVRRCTEEVEKRGLDVVSIYRLSGAVKLKIRIREMLEQDVIAADLSADTVPDIHAITAVLRDFLRELPEPLFTNALYRMILDALQVSLPGDNYAGAKLMLNILDCLPIVNQDTILHLLDHLKRVSSRSEVNKMTNEALAASLGPVLF-------FPSPEEAXXXXXXXXXXXXQAQTLLYILNIWPD 3714
G L +H+ GL + RDL C+L++D RAR+ +R + D F L++E L L WDP RHR C G V L + FR +++LA+ LEP+G+L+ +L + E P + +FG+PL +LV R+ GQ VP+I+++C ++E+RGL VV +YRL G+ +K +R+ E+D A LS D PDI+ IT +L+D+LRELP PL T LY+++L+A+ P + +L CLP V + T+ LLDHL+ VSS N+MT + LA GPVL P + S +D K + L Y+L WPD
Sbjct: 266 GRLSLHLYGLGGLRPAPGATPRDLCCLLQVDGEARARTGPLRGGPDFLRLDHTFHLELEAARLLRALVLAWDPGVRRHRPCAQGTVLLPTV---FRG--CQAQQLAVRLEPQGLLYAKLTLSEQQEA------PATAEPRVFGLPLPLLVERE-----RPPGQ---VPLIIQKCVGQIERRGLRVVGLYRLCGSAAVKKELRDAFERDSAAVCLSEDLYPDINVITGILKDYLRELPTPLITQPLYKVVLEAMARDPPNRVPPTTEGTRGLLSCLPDVERATLTLLLDHLRLVSSFHAYNRMTPQNLAVCFGPVLLPARQAPTRPRARSSGPGLASAVDFKHHIEVLHYLLQSWPD 602
BLAST of Rho GTPase-activating protein vs. Ensembl Human
Match: SYDE1 (synapse defective Rho GTPase homolog 1 [Source:HGNC Symbol;Acc:HGNC:25824]) HSP 1 Score: 182.57 bits (462), Expect = 4.711e-47 Identity = 127/356 (35.67%), Postives = 186/356 (52.25%), Query Frame = 1
Query: 2680 GMLVIHVVAGIGLNSSQTVV-RDLYCVLEIDSVRRARSM-IRTSTEIFEWDEIFELDVEDNDWLAFLFYQWDPR-NRHRLCFYGNVALRQLIERFRHSYTNSEKLALYLEPKGVLFIELLYLKINEVFQRFKMPVNTDA-LFGVPLEVLVSRDLNRQGETDGQECRVPIIVRRCTEEVEKRGLDVVSIYRLSGAVKLKIRIREMLEQDVIAADLSADTVPDIHAITAVLRDFLRELPEPLFTNALYRMILDALQVSLPGDNYAGAKLMLNILDCLPIVNQDTILHLLDHLKRVSSRSEVNKMTNEALAASLGPVLF-------FPSPEEAXXXXXXXXXXXXQAQTLLYILNIWPD 3714
G L +H+ GL + RDL C+L++D RAR+ +R + D F L++E L L WDP RHR C G V L + FR +++LA+ LEP+G+L+ +L + E P + +FG+PL +LV R+ GQ VP+I+++C ++E+RGL VV +YRL G+ +K +R+ E+D A LS D PDI+ IT +L+D+LRELP PL T LY+++L+A+ P + +L CLP V + T+ LLDHL+ VSS N+MT + LA GPVL P + S +D K + L Y+L WPD
Sbjct: 199 GRLSLHLYGLGGLRPAPGATPRDLCCLLQVDGEARARTGPLRGGPDFLRLDHTFHLELEAARLLRALVLAWDPGVRRHRPCAQGTVLLPTV---FRG--CQAQQLAVRLEPQGLLYAKLTLSEQQEA------PATAEPRVFGLPLPLLVERE-----RPPGQ---VPLIIQKCVGQIERRGLRVVGLYRLCGSAAVKKELRDAFERDSAAVCLSEDLYPDINVITGILKDYLRELPTPLITQPLYKVVLEAMARDPPNRVPPTTEGTRGLLSCLPDVERATLTLLLDHLRLVSSFHAYNRMTPQNLAVCFGPVLLPARQAPTRPRARSSGPGLASAVDFKHHIEVLHYLLQSWPD 535
BLAST of Rho GTPase-activating protein vs. Ensembl Human
Match: SYDE1 (synapse defective Rho GTPase homolog 1 [Source:HGNC Symbol;Acc:HGNC:25824]) HSP 1 Score: 139.043 bits (349), Expect = 1.419e-34 Identity = 96/258 (37.21%), Postives = 140/258 (54.26%), Query Frame = 1
Query: 2962 SYTNSEKLALYLEPKGVLFIELLYLKINEVFQRFKMPVNTDALFGVPLEVLVSRDLNRQGETDGQECRVPIIVRRCTEEVEKRGLDVVSIYRLSGAVKLKIRIREMLEQDVIAADLSADTVPDIHAITAVLRDFLRELPEPLFTNALYRMILDALQVSLPGDNYAGAKLMLNILDCLPIVNQDTILHLLDHLKRVSSRSEVNKMTNEALAASLGPVLFF-------PSPEEAXXXXXXXXXXXXQAQTLLYILNIWPD 3714
S +++LA+ LEP+G LLY K+ Q+ +FG+PL +LV R+ GQ VP+I+++C ++E+RGL VV +YRL G+ +K +R+ E+D A LS D PDI+ IT +L+D+LRELP PL T LY+++L+A+ P + +L CLP V + T+ LLDHL+ VSS N+MT + LA GPVL P + S +D K + L Y+L WPD
Sbjct: 15 SGCQAQQLAVRLEPQG-----LLYAKLTLSEQQEAPATAEPRVFGLPLPLLVERE-----RPPGQ---VPLIIQKCVGQIERRGLRVVGLYRLCGSAAVKKELRDAFERDSAAVCLSEDLYPDINVITGILKDYLRELPTPLITQPLYKVVLEAMARDPPNRVPPTTEGTRGLLSCLPDVERATLTLLLDHLRLVSSFHAYNRMTPQNLAVCFGPVLLPARQAPTRPRARSSGPGLASAVDFKHHIEVLHYLLQSWPD 259
BLAST of Rho GTPase-activating protein vs. Ensembl Human
Match: BCR (BCR activator of RhoGEF and GTPase [Source:HGNC Symbol;Acc:HGNC:1014]) HSP 1 Score: 138.272 bits (347), Expect = 5.164e-32 Identity = 119/372 (31.99%), Postives = 174/372 (46.77%), Query Frame = 1
Query: 2680 GMLVIHVVAGIGLNSSQTVVRDLYCVLEIDS----VRRARSMIRTSTEIFEWDEIFELDVEDNDWLAFLFYQW----------DPRNRHRLCFYGNVAL--RQLIERFRHSYTNSEKLALYLEPKGVLFIEL-LYLKINE-VFQRFKMPVNTD-ALFGVPLEVLVSRDLNRQGETDGQECRVPIIVRRCTEEVEKRGLDVVSIYRLSGAVKLKIRIREMLEQDVIAADLSADTVP-DIHAITAVLRDFLRELPEPLFTNALYRMILDALQVSLPGDNYAGAKLMLNILDCLPIVNQDTILHLLDHLKRVSSRSEVNKMTNEALAASLGPVLFFPSPEEA----------XXXXXXXXXXXXQAQTLLYILNI 3705
G L + V + G S +LYC LE+DS V +A++ + T W+E FE+++E + L L Y+ D + RL G V L + L +R + ++ + + IE+ L +K N F +MP +FGV + V+ R + +VP IVR+C EE+E+RG++ V IYR+SG ++ DV D+S D++AI L+ + RELPEPLFT+ Y + + +S D A MLN+L LP N T L LLDHLKRV+ + VNKM+ LA GP L PS +E+ D L+ Q Q LLY L +
Sbjct: 911 GFLNVIVHSATGFKQSS----NLYCTLEVDSFGYFVNKAKTRVYRDTAEPNWNEEFEIELEGSQTLRILCYEKCYNKTKIPKEDGESTDRLMGKGQVQLDPQALQDR------DWQRTVIAMNG-----IEVKLSVKFNSREFSLKRMPSRKQTGVFGVKIAVVTKR----------ERSKVPYIVRQCVEEIERRGMEEVGIYRVSGVATDIQALKAAF--DVNNKDVSVMMSEMDVNAIAGTLKLYFRELPEPLFTDEFYPNFAEGIALS---DPVAKESCMLNLLLSLPEANLLTFLFLLDHLKRVAEKEAVNKMSLHNLATVFGPTLLRPSEKESKLPANPSQPITMTDSWSLEVMSQVQVLLYFLQL 1252
BLAST of Rho GTPase-activating protein vs. Ensembl Celegans
Match: syd-1 (Rho GTPase-activating protein syd-1 [Source:UniProtKB/Swiss-Prot;Acc:Q86NH1]) HSP 1 Score: 215.312 bits (547), Expect = 4.266e-58 Identity = 131/395 (33.16%), Postives = 215/395 (54.43%), Query Frame = 1
Query: 2620 PVLASGGHPQRNKSATGYVSGMLVIHVVAGIGLN---SSQTVVRDLYCVLEIDSVRRARSMIRTSTEIFEWDEIFELDVEDNDWLAFLFYQWDPRNRHRLCFYGNVALRQLIERFRHSYTNSEKL-ALYLEPKGVLFIELLYLKINEVFQRFKMPVNTDALFGVPLEVLVSRDLNRQGETDGQECRVPIIVRRCTEEVEKRGLDVVSIYRLSGAVKLKIRIREMLEQDVIAADLSADTVPDIHAITAVLRDFLRELPEPLFTNALYRMILDALQVSLPGDNYAGAKLMLNILDCLPIVNQDTILHLLDHLKRVSSRSEVNKMTNEALAASLGPVLFFP----SP----EEAXXXXXXXXXXXXQAQTLLYILNIWPDESDHQYHSRDSKSKEPQK 3768
P+ A+G ++ + ++G+L +H+V G GL + + ++YCVLE+D RAR+ + T + F+W E F +DV + F Y W P+ RH+LC G++ +L+E F N +++ AL LEP+G L + + + + VF+R P + +FG+ L LV R+ PI++ R +E+EKRG+D +Y L G+V+ K +R LE + + +L+A+++PD + I +++DFLRELPEPL + ++ M+L+A V+LP D L+L I+DCL + ++ +L +LDHL V S N +T L+ P+LFF SP +K LD + + +L IL+IWP + + S DS + QK
Sbjct: 330 PLRAAGPGINVDRLSVSSLTGILYVHIVEGRGLKIPEKQKGLTEEMYCVLEVDEQHRARTGVSTIEQKFKWRETFHIDVVNATVSNFFVYSWHPQFRHKLCHKGSL---KLLEAFVVDQLNDDRVFALNLEPRGQLIVRIGFHDLQAVFRRTVNP-RLNGVFGISLSRLVQRERRD----------TPIVLTRLIQEIEKRGVDYSGLYVLCGSVEKKKMLRAELESNPLGTELAAESIPDTNVIACLIKDFLRELPEPLISPQIHGMLLEAASVALPNDVQTNRHLVLKIIDCLQLSAKNCLLLVLDHLSTVLCSSPHNGLTPTRLSLIFAPLLFFCLDTFSPYTISPTSKMAAVRTLDINQASSSLQMILSIWPSRVNSESGS-DSPATTCQK 709
BLAST of Rho GTPase-activating protein vs. Ensembl Celegans
Match: syd-1 (Rho GTPase-activating protein syd-1 [Source:UniProtKB/Swiss-Prot;Acc:Q86NH1]) HSP 1 Score: 216.083 bits (549), Expect = 4.656e-57 Identity = 131/395 (33.16%), Postives = 215/395 (54.43%), Query Frame = 1
Query: 2620 PVLASGGHPQRNKSATGYVSGMLVIHVVAGIGLN---SSQTVVRDLYCVLEIDSVRRARSMIRTSTEIFEWDEIFELDVEDNDWLAFLFYQWDPRNRHRLCFYGNVALRQLIERFRHSYTNSEKL-ALYLEPKGVLFIELLYLKINEVFQRFKMPVNTDALFGVPLEVLVSRDLNRQGETDGQECRVPIIVRRCTEEVEKRGLDVVSIYRLSGAVKLKIRIREMLEQDVIAADLSADTVPDIHAITAVLRDFLRELPEPLFTNALYRMILDALQVSLPGDNYAGAKLMLNILDCLPIVNQDTILHLLDHLKRVSSRSEVNKMTNEALAASLGPVLFFP----SP----EEAXXXXXXXXXXXXQAQTLLYILNIWPDESDHQYHSRDSKSKEPQK 3768
P+ A+G ++ + ++G+L +H+V G GL + + ++YCVLE+D RAR+ + T + F+W E F +DV + F Y W P+ RH+LC G++ +L+E F N +++ AL LEP+G L + + + + VF+R P + +FG+ L LV R+ PI++ R +E+EKRG+D +Y L G+V+ K +R LE + + +L+A+++PD + I +++DFLRELPEPL + ++ M+L+A V+LP D L+L I+DCL + ++ +L +LDHL V S N +T L+ P+LFF SP +K LD + + +L IL+IWP + + S DS + QK
Sbjct: 596 PLRAAGPGINVDRLSVSSLTGILYVHIVEGRGLKIPEKQKGLTEEMYCVLEVDEQHRARTGVSTIEQKFKWRETFHIDVVNATVSNFFVYSWHPQFRHKLCHKGSL---KLLEAFVVDQLNDDRVFALNLEPRGQLIVRIGFHDLQAVFRRTVNP-RLNGVFGISLSRLVQRERRD----------TPIVLTRLIQEIEKRGVDYSGLYVLCGSVEKKKMLRAELESNPLGTELAAESIPDTNVIACLIKDFLRELPEPLISPQIHGMLLEAASVALPNDVQTNRHLVLKIIDCLQLSAKNCLLLVLDHLSTVLCSSPHNGLTPTRLSLIFAPLLFFCLDTFSPYTISPTSKMAAVRTLDINQASSSLQMILSIWPSRVNSESGS-DSPATTCQK 975
BLAST of Rho GTPase-activating protein vs. Ensembl Celegans
Match: syd-1 (Rho GTPase-activating protein syd-1 [Source:UniProtKB/Swiss-Prot;Acc:Q86NH1]) HSP 1 Score: 214.157 bits (544), Expect = 1.509e-56 Identity = 126/376 (33.51%), Postives = 207/376 (55.05%), Query Frame = 1
Query: 2620 PVLASGGHPQRNKSATGYVSGMLVIHVVAGIGLN---SSQTVVRDLYCVLEIDSVRRARSMIRTSTEIFEWDEIFELDVEDNDWLAFLFYQWDPRNRHRLCFYGNVALRQLIERFRHSYTNSEKL-ALYLEPKGVLFIELLYLKINEVFQRFKMPVNTDALFGVPLEVLVSRDLNRQGETDGQECRVPIIVRRCTEEVEKRGLDVVSIYRLSGAVKLKIRIREMLEQDVIAADLSADTVPDIHAITAVLRDFLRELPEPLFTNALYRMILDALQVSLPGDNYAGAKLMLNILDCLPIVNQDTILHLLDHLKRVSSRSEVNKMTNEALAASLGPVLFFP----SP----EEAXXXXXXXXXXXXQAQTLLYILNIWP 3711
P+ A+G ++ + ++G+L +H+V G GL + + ++YCVLE+D RAR+ + T + F+W E F +DV + F Y W P+ RH+LC G++ +L+E F N +++ AL LEP+G L + + + + VF+R P + +FG+ L LV R+ PI++ R +E+EKRG+D +Y L G+V+ K +R LE + + +L+A+++PD + I +++DFLRELPEPL + ++ M+L+A V+LP D L+L I+DCL + ++ +L +LDHL V S N +T L+ P+LFF SP +K LD + + +L IL+IWP
Sbjct: 528 PLRAAGPGINVDRLSVSSLTGILYVHIVEGRGLKIPEKQKGLTEEMYCVLEVDEQHRARTGVSTIEQKFKWRETFHIDVVNATVSNFFVYSWHPQFRHKLCHKGSL---KLLEAFVVDQLNDDRVFALNLEPRGQLIVRIGFHDLQAVFRRTVNP-RLNGVFGISLSRLVQRERRD----------TPIVLTRLIQEIEKRGVDYSGLYVLCGSVEKKKMLRAELESNPLGTELAAESIPDTNVIACLIKDFLRELPEPLISPQIHGMLLEAASVALPNDVQTNRHLVLKIIDCLQLSAKNCLLLVLDHLSTVLCSSPHNGLTPTRLSLIFAPLLFFCLDTFSPYTISPTSKMAAVRTLDINQASSSLQMILSIWP 889
BLAST of Rho GTPase-activating protein vs. Ensembl Celegans
Match: tag-325 (WW domain-containing protein tag-325 [Source:UniProtKB/Swiss-Prot;Acc:P46941]) HSP 1 Score: 89.7373 bits (221), Expect = 6.726e-19 Identity = 56/150 (37.33%), Postives = 81/150 (54.00%), Query Frame = 1
Query: 3166 VPIIVRRCTEEVEKRGLDVVSIYRLSGAVKLKIRIREMLEQDVIAADLSADTVPDIHAITAVLRDFLRELPEPLFTNALYRMILDALQVSLPGDNYAGAKLMLNILDCLPIVNQDTILHLLDHLKRVSSRSEVNKMTNEALAASLGPVLF 3615
VP +R TE +E +GL+ IYR+SG + +IR +QD A +S + DIH +T L+ F REL +PLF +L++ A+Q+ + K +L LP N++T+ LL HL RV+S S N+M LA GP LF
Sbjct: 107 VPKFIRVITEVIESKGLETDGIYRVSGNLSAVQKIRCQADQDNYKALVSEE---DIHVLTGALKLFFRELTDPLFPISLHKEYTSAMQMPNATTRF---KKFEELLSRLPNENRETLKMLLRHLNRVASHSSQNRMQQHNLAIVFGPTLF 250
BLAST of Rho GTPase-activating protein vs. Ensembl Celegans
Match: tag-325 (WW domain-containing protein tag-325 [Source:UniProtKB/Swiss-Prot;Acc:P46941]) HSP 1 Score: 91.6633 bits (226), Expect = 2.583e-18 Identity = 56/150 (37.33%), Postives = 81/150 (54.00%), Query Frame = 1
Query: 3166 VPIIVRRCTEEVEKRGLDVVSIYRLSGAVKLKIRIREMLEQDVIAADLSADTVPDIHAITAVLRDFLRELPEPLFTNALYRMILDALQVSLPGDNYAGAKLMLNILDCLPIVNQDTILHLLDHLKRVSSRSEVNKMTNEALAASLGPVLF 3615
VP +R TE +E +GL+ IYR+SG + +IR +QD A +S + DIH +T L+ F REL +PLF +L++ A+Q+ + K +L LP N++T+ LL HL RV+S S N+M LA GP LF
Sbjct: 626 VPKFIRVITEVIESKGLETDGIYRVSGNLSAVQKIRCQADQDNYKALVSEE---DIHVLTGALKLFFRELTDPLFPISLHKEYTSAMQMPNATTRF---KKFEELLSRLPNENRETLKMLLRHLNRVASHSSQNRMQQHNLAIVFGPTLF 769
BLAST of Rho GTPase-activating protein vs. Ensembl Fly
Match: RhoGAP100F (gene:FBgn0039883 transcript:FBtr0304595) HSP 1 Score: 296.59 bits (758), Expect = 3.744e-81 Identity = 159/390 (40.77%), Postives = 233/390 (59.74%), Query Frame = 1
Query: 2575 LDPNEFRKIQTEQWPPVLASGGHPQRNKSATGYVSGMLVIHVVAGIGL---------NSSQTVVRDLYCVLEIDSVRRARSMIRTSTEIFEWDEIFELDVEDNDWLAFLFYQWDPRNRHRLCFYGNVALRQLIERFRHSYTNSEKLALYLEPKGVLFIELLYLKINEVFQRFKMP---VNTDALFGVPLEVLVSRDLNRQGETDGQECRVPIIVRRCTEEVEKRGLDVVSIYRLSGAVKLKIRIREMLEQDVIAADLSADTVPDIHAITAVLRDFLRELPEPLFTNALYRMILDALQVSLPGDNYAGAKLMLNILDCLPIVNQDTILHLLDHLKRVSSRSEVNKMTNEALAASLGPVLFFPSPEEAXXXXXXXXXXXXQAQTLLYILNIW 3708
++P EF K + ++ P++ GG +SGML IH++AG GL ++Q RDLYCV+E D V +AR+++R+ F+WDE FELD+ N L L Y WDP++RH+LC+ G ++L ++ + + +LAL +EP+G ++I + + +++R +P LFG LE +V NR+ + VPI++RRC EEVE+RGLD++ +YRL G+ K +RE E++ A +L+ + VPDI+ IT VL+D+LRELPEPLFT L++M +DAL V LP D AKLML+ILDCLP N+ T++ LLDHL V S SE NKM+ +ALA +GP L S A + +D + L Y+L IW
Sbjct: 767 INPAEFAKYKLDK--PIVDIGG-----------ISGMLWIHLLAGRGLRTAPEGAAGTATQGQTRDLYCVIECDRVHKARTVVRSGDLQFDWDESFELDLVGNKQLDVLVYSWDPQHRHKLCYRGAISLSSILRQ-----SPLHQLALKVEPRGTIYIRMRHTDPLALYKRRGLPSLRAGYPTLFGADLETVV----NRESKNAPGSAPVPIVLRRCVEEVERRGLDIIGLYRLCGSATKKRLLREAFERNSRAVELTPEHVPDINVITGVLKDYLRELPEPLFTRCLFQMTVDALAVCLPDDPEGNAKLMLSILDCLPRANRATLVFLLDHLSLVVSNSERNKMSAQALATVMGPPLMLHS---ASAQPGADIDHAQPIAVLKYLLQIW 1131
BLAST of Rho GTPase-activating protein vs. Ensembl Fly
Match: RhoGAP100F (gene:FBgn0039883 transcript:FBtr0309829) HSP 1 Score: 296.59 bits (758), Expect = 3.756e-81 Identity = 159/390 (40.77%), Postives = 233/390 (59.74%), Query Frame = 1
Query: 2575 LDPNEFRKIQTEQWPPVLASGGHPQRNKSATGYVSGMLVIHVVAGIGL---------NSSQTVVRDLYCVLEIDSVRRARSMIRTSTEIFEWDEIFELDVEDNDWLAFLFYQWDPRNRHRLCFYGNVALRQLIERFRHSYTNSEKLALYLEPKGVLFIELLYLKINEVFQRFKMP---VNTDALFGVPLEVLVSRDLNRQGETDGQECRVPIIVRRCTEEVEKRGLDVVSIYRLSGAVKLKIRIREMLEQDVIAADLSADTVPDIHAITAVLRDFLRELPEPLFTNALYRMILDALQVSLPGDNYAGAKLMLNILDCLPIVNQDTILHLLDHLKRVSSRSEVNKMTNEALAASLGPVLFFPSPEEAXXXXXXXXXXXXQAQTLLYILNIW 3708
++P EF K + ++ P++ GG +SGML IH++AG GL ++Q RDLYCV+E D V +AR+++R+ F+WDE FELD+ N L L Y WDP++RH+LC+ G ++L ++ + + +LAL +EP+G ++I + + +++R +P LFG LE +V NR+ + VPI++RRC EEVE+RGLD++ +YRL G+ K +RE E++ A +L+ + VPDI+ IT VL+D+LRELPEPLFT L++M +DAL V LP D AKLML+ILDCLP N+ T++ LLDHL V S SE NKM+ +ALA +GP L S A + +D + L Y+L IW
Sbjct: 770 INPAEFAKYKLDK--PIVDIGG-----------ISGMLWIHLLAGRGLRTAPEGAAGTATQGQTRDLYCVIECDRVHKARTVVRSGDLQFDWDESFELDLVGNKQLDVLVYSWDPQHRHKLCYRGAISLSSILRQ-----SPLHQLALKVEPRGTIYIRMRHTDPLALYKRRGLPSLRAGYPTLFGADLETVV----NRESKNAPGSAPVPIVLRRCVEEVERRGLDIIGLYRLCGSATKKRLLREAFERNSRAVELTPEHVPDINVITGVLKDYLRELPEPLFTRCLFQMTVDALAVCLPDDPEGNAKLMLSILDCLPRANRATLVFLLDHLSLVVSNSERNKMSAQALATVMGPPLMLHS---ASAQPGADIDHAQPIAVLKYLLQIW 1134
BLAST of Rho GTPase-activating protein vs. Ensembl Fly
Match: RhoGAP100F (gene:FBgn0039883 transcript:FBtr0302180) HSP 1 Score: 296.59 bits (758), Expect = 3.818e-81 Identity = 159/390 (40.77%), Postives = 233/390 (59.74%), Query Frame = 1
Query: 2575 LDPNEFRKIQTEQWPPVLASGGHPQRNKSATGYVSGMLVIHVVAGIGL---------NSSQTVVRDLYCVLEIDSVRRARSMIRTSTEIFEWDEIFELDVEDNDWLAFLFYQWDPRNRHRLCFYGNVALRQLIERFRHSYTNSEKLALYLEPKGVLFIELLYLKINEVFQRFKMP---VNTDALFGVPLEVLVSRDLNRQGETDGQECRVPIIVRRCTEEVEKRGLDVVSIYRLSGAVKLKIRIREMLEQDVIAADLSADTVPDIHAITAVLRDFLRELPEPLFTNALYRMILDALQVSLPGDNYAGAKLMLNILDCLPIVNQDTILHLLDHLKRVSSRSEVNKMTNEALAASLGPVLFFPSPEEAXXXXXXXXXXXXQAQTLLYILNIW 3708
++P EF K + ++ P++ GG +SGML IH++AG GL ++Q RDLYCV+E D V +AR+++R+ F+WDE FELD+ N L L Y WDP++RH+LC+ G ++L ++ + + +LAL +EP+G ++I + + +++R +P LFG LE +V NR+ + VPI++RRC EEVE+RGLD++ +YRL G+ K +RE E++ A +L+ + VPDI+ IT VL+D+LRELPEPLFT L++M +DAL V LP D AKLML+ILDCLP N+ T++ LLDHL V S SE NKM+ +ALA +GP L S A + +D + L Y+L IW
Sbjct: 769 INPAEFAKYKLDK--PIVDIGG-----------ISGMLWIHLLAGRGLRTAPEGAAGTATQGQTRDLYCVIECDRVHKARTVVRSGDLQFDWDESFELDLVGNKQLDVLVYSWDPQHRHKLCYRGAISLSSILRQ-----SPLHQLALKVEPRGTIYIRMRHTDPLALYKRRGLPSLRAGYPTLFGADLETVV----NRESKNAPGSAPVPIVLRRCVEEVERRGLDIIGLYRLCGSATKKRLLREAFERNSRAVELTPEHVPDINVITGVLKDYLRELPEPLFTRCLFQMTVDALAVCLPDDPEGNAKLMLSILDCLPRANRATLVFLLDHLSLVVSNSERNKMSAQALATVMGPPLMLHS---ASAQPGADIDHAQPIAVLKYLLQIW 1133
BLAST of Rho GTPase-activating protein vs. Ensembl Fly
Match: RhoGAP100F (gene:FBgn0039883 transcript:FBtr0302181) HSP 1 Score: 296.59 bits (758), Expect = 4.106e-81 Identity = 159/390 (40.77%), Postives = 233/390 (59.74%), Query Frame = 1
Query: 2575 LDPNEFRKIQTEQWPPVLASGGHPQRNKSATGYVSGMLVIHVVAGIGL---------NSSQTVVRDLYCVLEIDSVRRARSMIRTSTEIFEWDEIFELDVEDNDWLAFLFYQWDPRNRHRLCFYGNVALRQLIERFRHSYTNSEKLALYLEPKGVLFIELLYLKINEVFQRFKMP---VNTDALFGVPLEVLVSRDLNRQGETDGQECRVPIIVRRCTEEVEKRGLDVVSIYRLSGAVKLKIRIREMLEQDVIAADLSADTVPDIHAITAVLRDFLRELPEPLFTNALYRMILDALQVSLPGDNYAGAKLMLNILDCLPIVNQDTILHLLDHLKRVSSRSEVNKMTNEALAASLGPVLFFPSPEEAXXXXXXXXXXXXQAQTLLYILNIW 3708
++P EF K + ++ P++ GG +SGML IH++AG GL ++Q RDLYCV+E D V +AR+++R+ F+WDE FELD+ N L L Y WDP++RH+LC+ G ++L ++ + + +LAL +EP+G ++I + + +++R +P LFG LE +V NR+ + VPI++RRC EEVE+RGLD++ +YRL G+ K +RE E++ A +L+ + VPDI+ IT VL+D+LRELPEPLFT L++M +DAL V LP D AKLML+ILDCLP N+ T++ LLDHL V S SE NKM+ +ALA +GP L S A + +D + L Y+L IW
Sbjct: 780 INPAEFAKYKLDK--PIVDIGG-----------ISGMLWIHLLAGRGLRTAPEGAAGTATQGQTRDLYCVIECDRVHKARTVVRSGDLQFDWDESFELDLVGNKQLDVLVYSWDPQHRHKLCYRGAISLSSILRQ-----SPLHQLALKVEPRGTIYIRMRHTDPLALYKRRGLPSLRAGYPTLFGADLETVV----NRESKNAPGSAPVPIVLRRCVEEVERRGLDIIGLYRLCGSATKKRLLREAFERNSRAVELTPEHVPDINVITGVLKDYLRELPEPLFTRCLFQMTVDALAVCLPDDPEGNAKLMLSILDCLPRANRATLVFLLDHLSLVVSNSERNKMSAQALATVMGPPLMLHS---ASAQPGADIDHAQPIAVLKYLLQIW 1144
BLAST of Rho GTPase-activating protein vs. Ensembl Fly
Match: RhoGAP100F (gene:FBgn0039883 transcript:FBtr0343538) HSP 1 Score: 296.204 bits (757), Expect = 5.239e-81 Identity = 159/390 (40.77%), Postives = 233/390 (59.74%), Query Frame = 1
Query: 2575 LDPNEFRKIQTEQWPPVLASGGHPQRNKSATGYVSGMLVIHVVAGIGL---------NSSQTVVRDLYCVLEIDSVRRARSMIRTSTEIFEWDEIFELDVEDNDWLAFLFYQWDPRNRHRLCFYGNVALRQLIERFRHSYTNSEKLALYLEPKGVLFIELLYLKINEVFQRFKMP---VNTDALFGVPLEVLVSRDLNRQGETDGQECRVPIIVRRCTEEVEKRGLDVVSIYRLSGAVKLKIRIREMLEQDVIAADLSADTVPDIHAITAVLRDFLRELPEPLFTNALYRMILDALQVSLPGDNYAGAKLMLNILDCLPIVNQDTILHLLDHLKRVSSRSEVNKMTNEALAASLGPVLFFPSPEEAXXXXXXXXXXXXQAQTLLYILNIW 3708
++P EF K + ++ P++ GG +SGML IH++AG GL ++Q RDLYCV+E D V +AR+++R+ F+WDE FELD+ N L L Y WDP++RH+LC+ G ++L ++ + + +LAL +EP+G ++I + + +++R +P LFG LE +V NR+ + VPI++RRC EEVE+RGLD++ +YRL G+ K +RE E++ A +L+ + VPDI+ IT VL+D+LRELPEPLFT L++M +DAL V LP D AKLML+ILDCLP N+ T++ LLDHL V S SE NKM+ +ALA +GP L S A + +D + L Y+L IW
Sbjct: 780 INPAEFAKYKLDK--PIVDIGG-----------ISGMLWIHLLAGRGLRTAPEGAAGTATQGQTRDLYCVIECDRVHKARTVVRSGDLQFDWDESFELDLVGNKQLDVLVYSWDPQHRHKLCYRGAISLSSILRQ-----SPLHQLALKVEPRGTIYIRMRHTDPLALYKRRGLPSLRAGYPTLFGADLETVV----NRESKNAPGSAPVPIVLRRCVEEVERRGLDIIGLYRLCGSATKKRLLREAFERNSRAVELTPEHVPDINVITGVLKDYLRELPEPLFTRCLFQMTVDALAVCLPDDPEGNAKLMLSILDCLPRANRATLVFLLDHLSLVVSNSERNKMSAQALATVMGPPLMLHS---ASAQPGADIDHAQPIAVLKYLLQIW 1144
BLAST of Rho GTPase-activating protein vs. Ensembl Zebrafish
Match: SYDE2 (synapse defective 1, Rho GTPase, homolog 2 (C. elegans) [Source:NCBI gene;Acc:100333199]) HSP 1 Score: 199.904 bits (507), Expect = 8.829e-53 Identity = 131/404 (32.43%), Postives = 214/404 (52.97%), Query Frame = 1
Query: 2569 SRLDPNEFRKIQTEQWPPVLASGGHPQRNKSATGYVSGMLVIHVVAGIGLNSSQTVVRDLYCVLEIDSVRRARSMIRTS-TEIFEWDEIFELDVEDNDWLAFLFYQWD--PRNRHRLCFYGNVALRQLIERFRHSYTNSEKLALYLEPKGVLFIELLYLKINEVFQRFKMPVNTD----ALFGVPLEVLVSRDLNRQGETDGQECRVPIIVRRCTEEVEKRGLDVVSIYRLSGAVKLKIRIREMLEQDVIAADLSADTVPDIHAITAVLRDFLRELPEPLFTNALYRMILDALQVS--LPGDNY-----AGAKLMLNILDCLPIVNQDTILHLLDHLKRVSSRSEVNKMTNEALAASLGPVLFFPSPEEAXXXXXXXXXXXXQA---------QTLLYILNIWP 3711
+ LD + FR + P L Y+SG++ +H L + RD+YC +++DSV +AR+ + T T + D F +++E+ L + + W+ PR R+R+C +G V L L FR S T+ +LA+ LEP+G+++++L + ++ + ++ D +FGV +V R E G VP+++ +C E+E+RG VV +YRL G+ +K +RE E+D + +LS PDI+ IT VL+D+LRELP PL T LY +L+A+ L G+ A ++L +++LD LP V + ++ LLDHLKRV+S E+NKM + LA GPVL E + + + +D ++ A + L Y+L +WP
Sbjct: 140 TELDIDAFRSYSFTEQPKCLT-------------YISGLMSLHFYGAEDLKLPRVDSRDIYCAIQVDSVNKARTALLTCRTSFLDMDHTFNIELENAQHLKLVVFSWESTPR-RNRVCCHGTVVLPGL---FRVSKTH--QLAVRLEPRGMIYVKL------SLMEQRQNSLDGDHPQMQVFGVEARHVVER------EASG--LMVPLLIEKCISEIERRGCQVVGLYRLCGSAAVKKELREAFERDSHSVELSESNYPDINVITGVLKDYLRELPHPLITQQLYECVLEAMMKRPLLMGNAGCENTPADSQLTVSLLDILPDVEKASLKKLLDHLKRVASHHELNKMPCQNLAVCFGPVLLSQRQEASSQAKRVFIDSEELASALHFKKHIEVLHYLLQLWP 510
BLAST of Rho GTPase-activating protein vs. Ensembl Zebrafish
Match: SYDE1 (synapse defective Rho GTPase homolog 1 [Source:NCBI gene;Acc:568166]) HSP 1 Score: 186.422 bits (472), Expect = 1.688e-47 Identity = 111/331 (33.53%), Postives = 181/331 (54.68%), Query Frame = 1
Query: 2674 VSGMLVIHVVAGIGLNSSQTVVRDLYCVLEIDSVRRAR-SMIRTSTEIFEWDEIFELDVEDNDWLAFLFYQWDPRN------RHRLCFYGNVALRQLIERFRHSYTNSEKLALYLEPKGVLFIELLYLKINEVFQRFKMPVNTD--ALFGVPLEVLVSRDLNRQGETDGQECRVPIIVRRCTEEVEKRGLDVVSIYRLSGAVKLKIRIREMLEQDVIAADLSADTVPDIHAITAVLRDFLRELPEPLFTNALYRMILDALQVSLPGDNYAGAKL---MLNILDCLPIVNQDTILHLLDHLKRVSSRSEVNKMTNEALAASLGPVLFFPSPE 3630
+SG+L +H++ L + ++++C +++D V RAR S++ + F L++E L + N R+R+C G VA+ L + R S+ L + LEP+G+L+++L L+ + F P + A+FGV L LV E + RVP+I+++C E+++RGL VV +YRL G+ +K +R+ E+D A L+ + PD++ IT +L+D+LRELP PL T LY ++L+A+ V N + A+ +++L CLP + T+ LLDHL V+S S+ N+MT + LA GPVL PS E
Sbjct: 435 LSGLLTVHLLGVEELLRANKASKEVFCAIQVDGVTRARTSLLTCRGACLPLNHTFNLELERARLLKLVILTPATANASSAPARNRVCCVGAVAIPALFKACR-----SQHLCVRLEPRGLLYVKLTLLE--QFVSPFPRPGDLPPPAVFGVELRPLV--------EKESTALRVPLIIQKCVSEIQRRGLRVVGLYRLCGSAAVKKELRDAFERDSAAVTLNEELYPDVNVITGILKDYLRELPSPLITRTLYEVVLEAMTVRPAYRNDSDAQKSQSTVSLLHCLPEPERATLCFLLDHLSLVASYSDSNRMTCQNLAVCFGPVLLTPSQE 750
BLAST of Rho GTPase-activating protein vs. Ensembl Zebrafish
Match: si:dkey-91m11.5 (si:dkey-91m11.5 [Source:ZFIN;Acc:ZDB-GENE-060503-932]) HSP 1 Score: 137.502 bits (345), Expect = 5.885e-32 Identity = 115/374 (30.75%), Postives = 175/374 (46.79%), Query Frame = 1
Query: 2662 ATGYVSGMLVIHVVAGIGLNSSQTVVRDLYCVLEIDS----VRRARSMIRTSTEIFEWDEIFELDVEDNDWLAFLFYQW------DPRNRHRLCFYGNVALRQLIERFRHSYTNSEKLALYLEPKGVLFIELLYLKINEVFQRFKMPV-NTDALFGVPLEVLVSRDLNRQGETDGQECRVPIIVRRCTEEVEKRGLDVVSIYRLSGAVKLKIRIREMLEQD-----VIAADLSADTVPDIHAITAVLRDFLRELPEPLFTNALYRMILDALQVSLPGDNYAGAKLMLNILDCLPIVNQDTILHLLDHLKRVSSRSEVNKMTNEALAASLGPVLFFPSPEEAX----------XXXXXXXXXXXQAQTLLYILNI 3705
+TG + G L + V + GL S +LYC LE+DS V +A++ + T W+E FE+++E + L L Y D N R+ G + L S + + G+ ++L + F +MP +FGV + + R + +VP+IVR+C EE+E+RG++ V IYR+SG ++ + + VI +++ D++AI L+ + RELPEPLFT+ LY + + +S D+ A MLN+L LP N T L LLDHLKRV+ VNKM+ LA GP L PS +++K D L+ Q Q LLY L +
Sbjct: 929 STG-LCGFLNVIVHSATGLKQS----LNLYCTLEVDSFGYFVNKAKTRVYRDTTEPNWNEEFEIELEGSQTLRLLCYSKIKQCRDDGENIDRVMAKGQIQLDP------QSLQGKDWQRTVISMNGIE-VKLSMRFTSREFSLKRMPSRKQSGVFGVKIGAVTKR----------EHSKVPLIVRQCVEEIERRGMEEVGIYRVSGVATDIQALKAAFDANNKDVSVIMSEM------DVNAIAGTLKLYFRELPEPLFTDELYINFTEGIALS---DSVAKESCMLNLLLSLPEPNLLTFLFLLDHLKRVAENEIVNKMSFHNLATVFGPTLLRPSEKDSKIPSNPTQPISMSDSWSLEVMSQVQVLLYFLQL 1271
BLAST of Rho GTPase-activating protein vs. Ensembl Zebrafish
Match: si:dkey-91m11.5 (si:dkey-91m11.5 [Source:ZFIN;Acc:ZDB-GENE-060503-932]) HSP 1 Score: 137.117 bits (344), Expect = 5.906e-32 Identity = 115/374 (30.75%), Postives = 175/374 (46.79%), Query Frame = 1
Query: 2662 ATGYVSGMLVIHVVAGIGLNSSQTVVRDLYCVLEIDS----VRRARSMIRTSTEIFEWDEIFELDVEDNDWLAFLFYQW------DPRNRHRLCFYGNVALRQLIERFRHSYTNSEKLALYLEPKGVLFIELLYLKINEVFQRFKMPV-NTDALFGVPLEVLVSRDLNRQGETDGQECRVPIIVRRCTEEVEKRGLDVVSIYRLSGAVKLKIRIREMLEQD-----VIAADLSADTVPDIHAITAVLRDFLRELPEPLFTNALYRMILDALQVSLPGDNYAGAKLMLNILDCLPIVNQDTILHLLDHLKRVSSRSEVNKMTNEALAASLGPVLFFPSPEEAX----------XXXXXXXXXXXQAQTLLYILNI 3705
+TG + G L + V + GL S +LYC LE+DS V +A++ + T W+E FE+++E + L L Y D N R+ G + L S + + G+ ++L + F +MP +FGV + + R + +VP+IVR+C EE+E+RG++ V IYR+SG ++ + + VI +++ D++AI L+ + RELPEPLFT+ LY + + +S D+ A MLN+L LP N T L LLDHLKRV+ VNKM+ LA GP L PS +++K D L+ Q Q LLY L +
Sbjct: 866 STG-LCGFLNVIVHSATGLKQS----LNLYCTLEVDSFGYFVNKAKTRVYRDTTEPNWNEEFEIELEGSQTLRLLCYSKIKQCRDDGENMDRVMAKGQIQLDP------QSLQGKDWQRTVISMNGIE-VKLSMRFTSREFSLKRMPSRKQSGVFGVKIGAVTKR----------EHSKVPLIVRQCVEEIERRGMEEVGIYRVSGVATDIQALKAAFDANNKDVSVIMSEM------DVNAIAGTLKLYFRELPEPLFTDELYINFTEGIALS---DSVAKESCMLNLLLSLPEPNLLTFLFLLDHLKRVAENEIVNKMSFHNLATVFGPTLLRPSEKDSKIPSNPTQPISMSDSWSLEVMSQVQVLLYFLQL 1208
BLAST of Rho GTPase-activating protein vs. Ensembl Zebrafish
Match: si:dkey-91m11.5 (si:dkey-91m11.5 [Source:ZFIN;Acc:ZDB-GENE-060503-932]) HSP 1 Score: 137.117 bits (344), Expect = 6.950e-32 Identity = 115/374 (30.75%), Postives = 175/374 (46.79%), Query Frame = 1
Query: 2662 ATGYVSGMLVIHVVAGIGLNSSQTVVRDLYCVLEIDS----VRRARSMIRTSTEIFEWDEIFELDVEDNDWLAFLFYQW------DPRNRHRLCFYGNVALRQLIERFRHSYTNSEKLALYLEPKGVLFIELLYLKINEVFQRFKMPV-NTDALFGVPLEVLVSRDLNRQGETDGQECRVPIIVRRCTEEVEKRGLDVVSIYRLSGAVKLKIRIREMLEQD-----VIAADLSADTVPDIHAITAVLRDFLRELPEPLFTNALYRMILDALQVSLPGDNYAGAKLMLNILDCLPIVNQDTILHLLDHLKRVSSRSEVNKMTNEALAASLGPVLFFPSPEEAX----------XXXXXXXXXXXQAQTLLYILNI 3705
+TG + G L + V + GL S +LYC LE+DS V +A++ + T W+E FE+++E + L L Y D N R+ G + L S + + G+ ++L + F +MP +FGV + + R + +VP+IVR+C EE+E+RG++ V IYR+SG ++ + + VI +++ D++AI L+ + RELPEPLFT+ LY + + +S D+ A MLN+L LP N T L LLDHLKRV+ VNKM+ LA GP L PS +++K D L+ Q Q LLY L +
Sbjct: 878 STG-LCGFLNVIVHSATGLKQS----LNLYCTLEVDSFGYFVNKAKTRVYRDTTEPNWNEEFEIELEGSQTLRLLCYSKIKQCRDDGENMDRVMAKGQIQLDP------QSLQGKDWQRTVISMNGIE-VKLSMRFTSREFSLKRMPSRKQSGVFGVKIGAVTKR----------EHSKVPLIVRQCVEEIERRGMEEVGIYRVSGVATDIQALKAAFDANNKDVSVIMSEM------DVNAIAGTLKLYFRELPEPLFTDELYINFTEGIALS---DSVAKESCMLNLLLSLPEPNLLTFLFLLDHLKRVAENEIVNKMSFHNLATVFGPTLLRPSEKDSKIPSNPTQPISMSDSWSLEVMSQVQVLLYFLQL 1220
BLAST of Rho GTPase-activating protein vs. Ensembl Xenopus
Match: il6 (interleukin 6 [Source:Xenbase;Acc:XB-GENE-480186]) HSP 1 Score: 204.912 bits (520), Expect = 1.402e-52 Identity = 137/433 (31.64%), Postives = 223/433 (51.50%), Query Frame = 1
Query: 2671 YVSGMLVIHVVAGIGLNSSQTVVRDLYCVLEIDSVRRARSMIRTS-TEIFEWDEIFELDVEDNDWLAFLFYQWDPRNR-HRLCFYGNVALRQLIERFRHSYTNSEKLALYLEPKGVLFIELLYLKINEVFQRFKMPVNTDAL------FGVPLEVLVSRDLNRQGETDGQECRVPIIVRRCTEEVEKRGLDVVSIYRLSGAVKLKIRIREMLEQDVIAADLSADTVPDIHAITAVLRDFLRELPEPLFTNALYRMILDA-----LQVSLPG--DNYAGAKLMLNILDCLPIVNQDTILHLLDHLKRVSSRSEVNKMTNEALAASLGPVLFFPSPEEAXXXXXXXXXXXXQA---------QTLLYILNIWPDESDHQYHSRDSKSKEPQKIHSNSISNAQKITHITPSTRYSKPSPSTVRTSPNQTDTAATPR 3897
Y+SG++ +H L + +D++C +++DSV +AR+ + T T + D F +++E+ L + + WDP R +R+C +G V L L FR T + +LA+ LEP+G L+Y+K+N + ++++ ++ + FGV +V E + VP+++ +C E+EKRG VV +YRL G+ +K +RE E+D + L PDI+ IT VL+D+LRELP PL T LY +L A L+++ G ++ ++ +++LDCLP V + T+ LLDHLK V+S EVNKMT + LA GPVL E + ++ +D ++ A + L Y+L +WP +++ +KEP NS +T P R KP P T+ + PR
Sbjct: 812 YISGLMSLHFYGAEDLKPPKIDSKDVFCAIQVDSVNKARTALLTCRTTFLDMDHTFNIELENAQHLKLVVFSWDPTPRKNRVCCHGTVVLPAL---FR--VTKTHQLAVKLEPRG-----LIYVKLN-LMEQWENSLDRPGVDREPIVFGVEARKVV--------EKENAGLMVPLLMDKCITEIEKRGCQVVGLYRLCGSAAVKKELREAFERDSKSVGLCESQYPDINVITGVLKDYLRELPSPLITKHLYEAVLKAMAEKPLKMASSGCENDSRDSENTVSLLDCLPDVEKATLKMLLDHLKLVASYHEVNKMTCQNLAVCFGPVLLSQRQETSSHNNRVFIDSEELASALDFKKHIEVLHYLLQLWP--------VKNASAKEPAP---NST-----LTEQQPCLRRKKPRPQTLNLGSSDMSGVLRPR 1209
BLAST of Rho GTPase-activating protein vs. Ensembl Xenopus
Match: il6 (interleukin 6 [Source:Xenbase;Acc:XB-GENE-480186]) HSP 1 Score: 204.912 bits (520), Expect = 1.764e-52 Identity = 137/433 (31.64%), Postives = 223/433 (51.50%), Query Frame = 1
Query: 2671 YVSGMLVIHVVAGIGLNSSQTVVRDLYCVLEIDSVRRARSMIRTS-TEIFEWDEIFELDVEDNDWLAFLFYQWDPRNR-HRLCFYGNVALRQLIERFRHSYTNSEKLALYLEPKGVLFIELLYLKINEVFQRFKMPVNTDAL------FGVPLEVLVSRDLNRQGETDGQECRVPIIVRRCTEEVEKRGLDVVSIYRLSGAVKLKIRIREMLEQDVIAADLSADTVPDIHAITAVLRDFLRELPEPLFTNALYRMILDA-----LQVSLPG--DNYAGAKLMLNILDCLPIVNQDTILHLLDHLKRVSSRSEVNKMTNEALAASLGPVLFFPSPEEAXXXXXXXXXXXXQA---------QTLLYILNIWPDESDHQYHSRDSKSKEPQKIHSNSISNAQKITHITPSTRYSKPSPSTVRTSPNQTDTAATPR 3897
Y+SG++ +H L + +D++C +++DSV +AR+ + T T + D F +++E+ L + + WDP R +R+C +G V L L FR T + +LA+ LEP+G L+Y+K+N + ++++ ++ + FGV +V E + VP+++ +C E+EKRG VV +YRL G+ +K +RE E+D + L PDI+ IT VL+D+LRELP PL T LY +L A L+++ G ++ ++ +++LDCLP V + T+ LLDHLK V+S EVNKMT + LA GPVL E + ++ +D ++ A + L Y+L +WP +++ +KEP NS +T P R KP P T+ + PR
Sbjct: 1039 YISGLMSLHFYGAEDLKPPKIDSKDVFCAIQVDSVNKARTALLTCRTTFLDMDHTFNIELENAQHLKLVVFSWDPTPRKNRVCCHGTVVLPAL---FR--VTKTHQLAVKLEPRG-----LIYVKLN-LMEQWENSLDRPGVDREPIVFGVEARKVV--------EKENAGLMVPLLMDKCITEIEKRGCQVVGLYRLCGSAAVKKELREAFERDSKSVGLCESQYPDINVITGVLKDYLRELPSPLITKHLYEAVLKAMAEKPLKMASSGCENDSRDSENTVSLLDCLPDVEKATLKMLLDHLKLVASYHEVNKMTCQNLAVCFGPVLLSQRQETSSHNNRVFIDSEELASALDFKKHIEVLHYLLQLWP--------VKNASAKEPAP---NST-----LTEQQPCLRRKKPRPQTLNLGSSDMSGVLRPR 1436
BLAST of Rho GTPase-activating protein vs. Ensembl Xenopus
Match: bcr (BCR, RhoGEF and GTPase activating protein [Source:NCBI gene;Acc:100170543]) HSP 1 Score: 132.109 bits (331), Expect = 2.770e-30 Identity = 115/377 (30.50%), Postives = 176/377 (46.68%), Query Frame = 1
Query: 2680 GMLVIHVVAGIGLNSSQTVVRDLYCVLEIDS----VRRARSMIRTSTEIFEWDEIFELDVEDNDWLAFLFYQWDP-RNR----------HRLCFYGNVALRQ---LIERFRHSYTNSEKLALYLEPKGVLFIELLYLKI-NEVFQRFKMPVNTD-ALFGVPLEVLVSRDLNRQGETDGQECRVPIIVRRCTEEVEKRGLDVVSIYRLSGAVKLKIRIREMLEQD-----VIAADLSADTVPDIHAITAVLRDFLRELPEPLFTNALYRMILDALQVSLPGDNYAGAKLMLNILDCLPIVNQDTILHLLDHLKRVSSRSEVNKMTNEALAASLGPVLFFPSPEEAX----------XXXXXXXXXXXQAQTLLYILNI 3705
G L + V + G S +L+C LE+DS V +A++ + +T W+E FE+++E + L L Y+ RNR R+ G V L L + + S + +++ +E K L +K + F ++P +FGV + V+ R+ +VP IVR+C EE+E+RGL+ V IYR+SG ++ + + V+ +D+ D++AI L+ + RELP PLFT+ LY + + +S D A MLN+L LP N T L LLDHLKRV+ NKM+ LA GP L PS +++K D L+ Q Q LLY L +
Sbjct: 798 GFLNVIVHSATGFQQSS----NLFCTLEVDSFGYFVNKAKTRVYRNTTEPNWNEEFEIELEGSQTLRILCYEKSCNRNRPMKEDGGDSSERMVAKGQVQLESQLALGKDWHRSVVSMNGVSILIEVK-------LSMKFTSREFSLKRLPSRKQTGVFGVKIAVVTKRE----------RSKVPYIVRQCVEEIERRGLEEVGIYRVSGVATDIQALKNAFDANNKDVSVMMSDM------DVNAIAGTLKLYFRELPAPLFTDELYPNFAEGIALS---DPVAKESCMLNLLLSLPEPNLLTFLFLLDHLKRVAENESQNKMSLHNLATVFGPTLLRPSEKDSKIPVNPTQPISMADSWSLEVMSQVQVLLYFLQL 1144
BLAST of Rho GTPase-activating protein vs. Ensembl Xenopus
Match: bcr (BCR, RhoGEF and GTPase activating protein [Source:NCBI gene;Acc:100170543]) HSP 1 Score: 129.413 bits (324), Expect = 1.892e-29 Identity = 113/373 (30.29%), Postives = 171/373 (45.84%), Query Frame = 1
Query: 2680 GMLVIHVVAGIGLNSSQTVVRDLYCVLEIDS----VRRARSMIRTSTEIFEWDEIFELDVEDNDWLAFLFYQWDP-RNR----------HRLCFYGNVALRQLIERFRHSYTNSEKLALYLEPKGVLFIELLYLKINEVFQRFKMPVNTD-ALFGVPLEVLVSRDLNRQGETDGQECRVPIIVRRCTEEVEKRGLDVVSIYRLSGAVKLKIRIREMLEQD-----VIAADLSADTVPDIHAITAVLRDFLRELPEPLFTNALYRMILDALQVSLPGDNYAGAKLMLNILDCLPIVNQDTILHLLDHLKRVSSRSEVNKMTNEALAASLGPVLFFPSPEEAX----------XXXXXXXXXXXQAQTLLYILNI 3705
G L + V + G S +L+C LE+DS V +A++ + +T W+E FE+++E + L L Y+ RNR R+ G V L L + + S + + + L K + F ++P +FGV + V+ R+ +VP IVR+C EE+E+RGL+ V IYR+SG ++ + + V+ +D+ D++AI L+ + RELP PLFT+ LY + + +S D A MLN+L LP N T L LLDHLKRV+ NKM+ LA GP L PS +++K D L+ Q Q LLY L +
Sbjct: 775 GFLNVIVHSATGFQQSS----NLFCTLEVDSFGYFVNKAKTRVYRNTTEPNWNEEFEIELEGSQTLRILCYEKSCNRNRPMKEDGGDSSERMVAKGQVQL-ALGKDWHRSVVSMNGIEVKLSMKFT----------SREFSLKRLPSRKQTGVFGVKIAVVTKRE----------RSKVPYIVRQCVEEIERRGLEEVGIYRVSGVATDIQALKNAFDANNKDVSVMMSDM------DVNAIAGTLKLYFRELPAPLFTDELYPNFAEGIALS---DPVAKESCMLNLLLSLPEPNLLTFLFLLDHLKRVAENESQNKMSLHNLATVFGPTLLRPSEKDSKIPVNPTQPISMADSWSLEVMSQVQVLLYFLQL 1113
BLAST of Rho GTPase-activating protein vs. Ensembl Xenopus
Match: bcr (BCR, RhoGEF and GTPase activating protein [Source:NCBI gene;Acc:100170543]) HSP 1 Score: 129.028 bits (323), Expect = 3.042e-29 Identity = 111/369 (30.08%), Postives = 175/369 (47.43%), Query Frame = 1
Query: 2680 GMLVIHVVAGIGLNSSQTVVRDLYCVLEIDS----VRRARSMIRTSTEIFEWDEIFELDVEDNDWLAFLFYQWDP-RNRHRLCFYGNVALRQLIERFRHSYTNSEKLALYLE-PKGVLFIELLYLKINEVFQRFKMPVN------TDALFGVPLEVLVSRDLNRQGETDGQECRVPIIVRRCTEEVEKRGLDVVSIYRLSGAVKLKIRIREMLEQD-----VIAADLSADTVPDIHAITAVLRDFLRELPEPLFTNALYRMILDALQVSLPGDNYAGAKLMLNILDCLPIVNQDTILHLLDHLKRVSSRSEVNKMTNEALAASLGPVLFFPSPEEAX----------XXXXXXXXXXXQAQTLLYILNI 3705
G L + V + G S +L+C LE+DS V +A++ + +T W+E FE+++E + L L Y+ RNR G+ + R + + +LAL + + V+ + + +K++ F + + +FGV + V+ R+ +VP IVR+C EE+E+RGL+ V IYR+SG ++ + + V+ +D+ D++AI L+ + RELP PLFT+ LY + + +S D A MLN+L LP N T L LLDHLKRV+ NKM+ LA GP L PS +++K D L+ Q Q LLY L +
Sbjct: 788 GFLNVIVHSATGFQQSS----NLFCTLEVDSFGYFVNKAKTRVYRNTTEPNWNEEFEIELEGSQTLRILCYEKSCNRNRPMKEDGGDSSERMVA---KGQVQLESQLALGKDWHRSVVSMNGIEVKLSMKFTSREFSLKRLPSRKQTGVFGVKIAVVTKRE----------RSKVPYIVRQCVEEIERRGLEEVGIYRVSGVATDIQALKNAFDANNKDVSVMMSDM------DVNAIAGTLKLYFRELPAPLFTDELYPNFAEGIALS---DPVAKESCMLNLLLSLPEPNLLTFLFLLDHLKRVAENESQNKMSLHNLATVFGPTLLRPSEKDSKIPVNPTQPISMADSWSLEVMSQVQVLLYFLQL 1130
BLAST of Rho GTPase-activating protein vs. Ensembl Mouse
Match: Syde2 (synapse defective 1, Rho GTPase, homolog 2 (C. elegans) [Source:MGI Symbol;Acc:MGI:3036264]) HSP 1 Score: 216.853 bits (551), Expect = 7.450e-57 Identity = 164/559 (29.34%), Postives = 271/559 (48.48%), Query Frame = 1
Query: 2371 FDNATRTDLSYFRAPNNVLEYSSPGYAFSSNAQNDFRSTASAPSFRSLRQPSRPKDQQMDHGEQSV------SRLDPNEFRKIQTEQWPPVLASGGHPQRNKSATGYVSGMLVIHVVAGIGLNSSQTVVRDLYCVLEIDSVRRARSMIRTS-TEIFEWDEIFELDVEDNDWLAFLFYQWDPR-NRHRLCFYGNVALRQLIERFRHSYTNSEKLALYLEPKGVLFIELLYLKINEVFQRFKMPVNTDA-LFGVPLEVLVSRDLNRQGETDGQECRVPIIVRRCTEEVEKRGLDVVSIYRLSGAVKLKIRIREMLEQDVIAADLSADTVPDIHAITAVLRDFLRELPEPLFTNALYRMILDA-----LQVSLPG--DNYAGAKLMLNILDCLPIVNQDTILHLLDHLKRVSSRSEVNKMTNEALAASLGPVLFFPSPEEAXXXXXXXXXXXXQA---------QTLLYILNIWPDESDHQYHSRDSKSKEPQKIHSNSISNAQKITHITPSTRYSKPSPSTV-RTSPNQTDTAATPRKSDAPINSGMNSAENVRSQNNVKN 3969
D + SY + P +YS G + S +P R+ R + ++ G ++V + LD FR P + Y+SG++ +H GL + +D++C +++DSV +AR+ + T T + D F +++E+ L + + W+P R+R+C +G V L L FR T + +LA+ LEP+G++++++ ++ E + N +A +FGV ++ +V E + VP+++++C E+EKRG VV +YRL G+ +K +RE E+D L + PDI+ IT VL+D+LRELP PL T LY +LDA L++S G + + ++L +++LDCLP V + T+ LLDHLK V+S EVNKMT + LA GPVL E + ++ D ++ A + L Y+L +WP + RDS E S+S++ ++ S P S V RT + D+ + R + + G + + N R NVKN
Sbjct: 447 LDTTVSSRHSYRKKPLGSSKYSCKG---------GYLSDGDSPELRT-RSSKHGSEHKLGKGRETVPSSCSKNELDIGAFRHYSFADQP-------------KCSQYISGLMSVHFYGAEGLKPPRIDSKDVFCAIQVDSVNKARTALLTCRTTFLDMDHTFNIEIENAQHLKLVVFSWEPTPRRNRVCCHGTVVLPAL---FR--VTKTHQLAVKLEPRGLIYVKVTLMEQWE-NSLHGLDKNREAVMFGVDIQKVV--------EKENVGLMVPLLIQKCIVEIEKRGCQVVGLYRLCGSAAVKKELREAFEKDSKTVGLCENQYPDINVITGVLKDYLRELPSPLITKQLYEAVLDAMAKSPLKMSSSGCENEPSDSRLTVDLLDCLPDVEKATLKMLLDHLKLVASYHEVNKMTCQNLAVCFGPVLLNQRQEASTHNNRVFTDSEELASALDFKKHIEVLHYLLQLWPVQRLTVKEPRDSLCLE----QSSSLNYLRRKKERPCVLNLSGPDSSGVLRTRQARLDSPLSNRYAGDWSSCGESYSLNTR--GNVKN 962
BLAST of Rho GTPase-activating protein vs. Ensembl Mouse
Match: Syde2 (synapse defective 1, Rho GTPase, homolog 2 (C. elegans) [Source:MGI Symbol;Acc:MGI:3036264]) HSP 1 Score: 216.853 bits (551), Expect = 7.561e-57 Identity = 164/559 (29.34%), Postives = 271/559 (48.48%), Query Frame = 1
Query: 2371 FDNATRTDLSYFRAPNNVLEYSSPGYAFSSNAQNDFRSTASAPSFRSLRQPSRPKDQQMDHGEQSV------SRLDPNEFRKIQTEQWPPVLASGGHPQRNKSATGYVSGMLVIHVVAGIGLNSSQTVVRDLYCVLEIDSVRRARSMIRTS-TEIFEWDEIFELDVEDNDWLAFLFYQWDPR-NRHRLCFYGNVALRQLIERFRHSYTNSEKLALYLEPKGVLFIELLYLKINEVFQRFKMPVNTDA-LFGVPLEVLVSRDLNRQGETDGQECRVPIIVRRCTEEVEKRGLDVVSIYRLSGAVKLKIRIREMLEQDVIAADLSADTVPDIHAITAVLRDFLRELPEPLFTNALYRMILDA-----LQVSLPG--DNYAGAKLMLNILDCLPIVNQDTILHLLDHLKRVSSRSEVNKMTNEALAASLGPVLFFPSPEEAXXXXXXXXXXXXQA---------QTLLYILNIWPDESDHQYHSRDSKSKEPQKIHSNSISNAQKITHITPSTRYSKPSPSTV-RTSPNQTDTAATPRKSDAPINSGMNSAENVRSQNNVKN 3969
D + SY + P +YS G + S +P R+ R + ++ G ++V + LD FR P + Y+SG++ +H GL + +D++C +++DSV +AR+ + T T + D F +++E+ L + + W+P R+R+C +G V L L FR T + +LA+ LEP+G++++++ ++ E + N +A +FGV ++ +V E + VP+++++C E+EKRG VV +YRL G+ +K +RE E+D L + PDI+ IT VL+D+LRELP PL T LY +LDA L++S G + + ++L +++LDCLP V + T+ LLDHLK V+S EVNKMT + LA GPVL E + ++ D ++ A + L Y+L +WP + RDS E S+S++ ++ S P S V RT + D+ + R + + G + + N R NVKN
Sbjct: 448 LDTTVSSRHSYRKKPLGSSKYSCKG---------GYLSDGDSPELRT-RSSKHGSEHKLGKGRETVPSSCSKNELDIGAFRHYSFADQP-------------KCSQYISGLMSVHFYGAEGLKPPRIDSKDVFCAIQVDSVNKARTALLTCRTTFLDMDHTFNIEIENAQHLKLVVFSWEPTPRRNRVCCHGTVVLPAL---FR--VTKTHQLAVKLEPRGLIYVKVTLMEQWE-NSLHGLDKNREAVMFGVDIQKVV--------EKENVGLMVPLLIQKCIVEIEKRGCQVVGLYRLCGSAAVKKELREAFEKDSKTVGLCENQYPDINVITGVLKDYLRELPSPLITKQLYEAVLDAMAKSPLKMSSSGCENEPSDSRLTVDLLDCLPDVEKATLKMLLDHLKLVASYHEVNKMTCQNLAVCFGPVLLNQRQEASTHNNRVFTDSEELASALDFKKHIEVLHYLLQLWPVQRLTVKEPRDSLCLE----QSSSLNYLRRKKERPCVLNLSGPDSSGVLRTRQARLDSPLSNRYAGDWSSCGESYSLNTR--GNVKN 963
BLAST of Rho GTPase-activating protein vs. Ensembl Mouse
Match: Syde2 (synapse defective 1, Rho GTPase, homolog 2 (C. elegans) [Source:MGI Symbol;Acc:MGI:3036264]) HSP 1 Score: 216.083 bits (549), Expect = 3.315e-56 Identity = 146/484 (30.17%), Postives = 241/484 (49.79%), Query Frame = 1
Query: 2371 FDNATRTDLSYFRAPNNVLEYSSPGYAFSSNAQNDFRSTASAPSFRSLRQPSRPKDQQMDHGEQSV------SRLDPNEFRKIQTEQWPPVLASGGHPQRNKSATGYVSGMLVIHVVAGIGLNSSQTVVRDLYCVLEIDSVRRARSMIRTS-TEIFEWDEIFELDVEDNDWLAFLFYQWDPR-NRHRLCFYGNVALRQLIERFRHSYTNSEKLALYLEPKGVLFIELLYLKINEVFQRFKMPVNTDA-LFGVPLEVLVSRDLNRQGETDGQECRVPIIVRRCTEEVEKRGLDVVSIYRLSGAVKLKIRIREMLEQDVIAADLSADTVPDIHAITAVLRDFLRELPEPLFTNALYRMILDA-----LQVSLPG--DNYAGAKLMLNILDCLPIVNQDTILHLLDHLKRVSSRSEVNKMTNEALAASLGPVLFFPSPEEAXXXXXXXXXXXXQA---------QTLLYILNIWPDESDHQYHSRDS 3747
D + SY + P +YS G + S +P R+ R + ++ G ++V + LD FR P + Y+SG++ +H GL + +D++C +++DSV +AR+ + T T + D F +++E+ L + + W+P R+R+C +G V L L FR T + +LA+ LEP+G++++++ ++ E + N +A +FGV ++ +V E + VP+++++C E+EKRG VV +YRL G+ +K +RE E+D L + PDI+ IT VL+D+LRELP PL T LY +LDA L++S G + + ++L +++LDCLP V + T+ LLDHLK V+S EVNKMT + LA GPVL E + ++ D ++ A + L Y+L +WP + RDS
Sbjct: 715 LDTTVSSRHSYRKKPLGSSKYSCKG---------GYLSDGDSPELRT-RSSKHGSEHKLGKGRETVPSSCSKNELDIGAFRHYSFADQP-------------KCSQYISGLMSVHFYGAEGLKPPRIDSKDVFCAIQVDSVNKARTALLTCRTTFLDMDHTFNIEIENAQHLKLVVFSWEPTPRRNRVCCHGTVVLPAL---FR--VTKTHQLAVKLEPRGLIYVKVTLMEQWE-NSLHGLDKNREAVMFGVDIQKVV--------EKENVGLMVPLLIQKCIVEIEKRGCQVVGLYRLCGSAAVKKELREAFEKDSKTVGLCENQYPDINVITGVLKDYLRELPSPLITKQLYEAVLDAMAKSPLKMSSSGCENEPSDSRLTVDLLDCLPDVEKATLKMLLDHLKLVASYHEVNKMTCQNLAVCFGPVLLNQRQEASTHNNRVFTDSEELASALDFKKHIEVLHYLLQLWPVQRLTVKEPRDS 1161
BLAST of Rho GTPase-activating protein vs. Ensembl Mouse
Match: Syde1 (synapse defective 1, Rho GTPase, homolog 1 (C. elegans) [Source:MGI Symbol;Acc:MGI:1918959]) HSP 1 Score: 196.052 bits (497), Expect = 2.201e-51 Identity = 132/356 (37.08%), Postives = 192/356 (53.93%), Query Frame = 1
Query: 2680 GMLVIHVVAGIGLNSSQTVV-RDLYCVLEIDSVRRARSM-IRTSTEIFEWDEIFELDVEDNDWLAFLFYQWDPR-NRHRLCFYGNVALRQLIERFRHSYTNSEKLALYLEPKGVLFIELLYLKINEVFQRFKMPVNTDA-LFGVPLEVLVSRDLNRQGETDGQECRVPIIVRRCTEEVEKRGLDVVSIYRLSGAVKLKIRIREMLEQDVIAADLSADTVPDIHAITAVLRDFLRELPEPLFTNALYRMILDALQVSLPGDNYAGAKLMLNILDCLPIVNQDTILHLLDHLKRVSSRSEVNKMTNEALAASLGPVLF-------FPSPEEAXXXXXXXXXXXXQAQTLLYILNIWPD 3714
G L +H+ GL S RDL C+L++D V RAR+ +R+ + D F L++E L L WDP RHR C G V L + FR +++LA+ LEP+G+L+ +L + E P + +FG+PL++LV R+ ++ GQ VP+I+R+C ++E RGL VV +YRL G+ +K +R+ EQD A LS D PDI+ IT +L+D+LRELP PL T LY+++L+A+ P G + +L CLP V + T+ LLDHL+ VSS N+MT + LA GPVL P + S +D K+ + L Y+L WPD
Sbjct: 266 GRLSLHLYGLGGLRPSPGATPRDLCCLLQVDGVARARTGPLRSGPDFLRLDHTFHLELEAARLLRALVLAWDPGVRRHRPCAQGTVLLPTI---FRG--CQAQQLAVRLEPQGLLYAKLTLSEQQEA------PATAEPRVFGLPLQLLVERE-----QSPGQ---VPLIIRKCVGQIECRGLRVVGLYRLCGSAAVKKELRDAFEQDSAAVCLSEDVYPDINVITGILKDYLRELPTPLITQPLYQVVLEAMAQGHPSRASLGPEGTRGLLRCLPDVERATLTLLLDHLRLVSSFHTHNRMTPQNLAVCFGPVLLPARQTPSRPRLRSSGPGVTSAVDFKRHIEVLHYLLQSWPD 602
BLAST of Rho GTPase-activating protein vs. Ensembl Mouse
Match: Bcr (BCR activator of RhoGEF and GTPase [Source:MGI Symbol;Acc:MGI:88141]) HSP 1 Score: 136.732 bits (343), Expect = 8.648e-32 Identity = 110/363 (30.30%), Postives = 172/363 (47.38%), Query Frame = 1
Query: 2680 GMLVIHVVAGIGLNSSQTVVRDLYCVLEIDS----VRRARSMIRTSTEIFEWDEIFELDVEDNDWLAFLFYQWDPRNRHRLCFYGNVALRQLIERFR-----HSYTNSEKLALYLEPKGVLFIELLYLKINEVFQRFKMPVNTD-ALFGVPLEVLVSRDLNRQGETDGQECRVPIIVRRCTEEVEKRGLDVVSIYRLSGAVKLKIRIREMLEQDVIAADLSADTVP-DIHAITAVLRDFLRELPEPLFTNALYRMILDALQVSLPGDNYAGAKLMLNILDCLPIVNQDTILHLLDHLKRVSSRSEVNKMTNEALAASLGPVLFFPSPEEA----------XXXXXXXXXXXXQAQTLLYILNI 3705
G L + V + G S +LYC LE+DS V +A++ + T W+E FE+++E + L L Y+ N+ ++ + +L+ + + + + + ++ G+ ++L + F +MP +FGV + V+ R+ +VP IVR+C EE+E+RG++ V IYR+SG ++ DV D+S D++AI L+ + RELPEPLFT+ Y + + +S D A MLN+L LP N T L LLDHLKRV+ + VNKM+ LA GP L PS +E+ D L+ Q Q LLY L +
Sbjct: 910 GFLHVIVHSATGFKQSS----NLYCTLEVDSFGYFVNKAKTRVYRDTTEPNWNEEFEIELEGSQTLRILCYE-KCYNKMKMTKEDGESADKLMGKGQVQLDPQTLQDRDWQRTVIDMNGIE-VKLSVKFTSREFSLKRMPSRKQTGVFGVKIAVVTKRE----------RSKVPYIVRQCVEEIERRGMEEVGIYRVSGVATDIQALKAAF--DVNNKDVSVMMSEMDVNAIAGTLKLYFRELPEPLFTDEFYPNFAEGIALS---DPVAKESCMLNLLLSLPEANLLTFLFLLDHLKRVAEKETVNKMSLHNLATVFGPTLLRPSEKESKLPANPSQPITMTDSWSLEVMSQVQVLLYFLQL 1251
BLAST of Rho GTPase-activating protein vs. UniProt/SwissProt
Match: sp|Q9V9S7|SYDE_DROME (Rho GTPase-activating protein 100F OS=Drosophila melanogaster OX=7227 GN=RhoGAP100F PE=1 SV=2) HSP 1 Score: 296.59 bits (758), Expect = 4.116e-80 Identity = 159/390 (40.77%), Postives = 233/390 (59.74%), Query Frame = 1
Query: 2575 LDPNEFRKIQTEQWPPVLASGGHPQRNKSATGYVSGMLVIHVVAGIGL---------NSSQTVVRDLYCVLEIDSVRRARSMIRTSTEIFEWDEIFELDVEDNDWLAFLFYQWDPRNRHRLCFYGNVALRQLIERFRHSYTNSEKLALYLEPKGVLFIELLYLKINEVFQRFKMP---VNTDALFGVPLEVLVSRDLNRQGETDGQECRVPIIVRRCTEEVEKRGLDVVSIYRLSGAVKLKIRIREMLEQDVIAADLSADTVPDIHAITAVLRDFLRELPEPLFTNALYRMILDALQVSLPGDNYAGAKLMLNILDCLPIVNQDTILHLLDHLKRVSSRSEVNKMTNEALAASLGPVLFFPSPEEAXXXXXXXXXXXXQAQTLLYILNIW 3708
++P EF K + ++ P++ GG +SGML IH++AG GL ++Q RDLYCV+E D V +AR+++R+ F+WDE FELD+ N L L Y WDP++RH+LC+ G ++L ++ + + +LAL +EP+G ++I + + +++R +P LFG LE +V NR+ + VPI++RRC EEVE+RGLD++ +YRL G+ K +RE E++ A +L+ + VPDI+ IT VL+D+LRELPEPLFT L++M +DAL V LP D AKLML+ILDCLP N+ T++ LLDHL V S SE NKM+ +ALA +GP L S A + +D + L Y+L IW
Sbjct: 780 INPAEFAKYKLDK--PIVDIGG-----------ISGMLWIHLLAGRGLRTAPEGAAGTATQGQTRDLYCVIECDRVHKARTVVRSGDLQFDWDESFELDLVGNKQLDVLVYSWDPQHRHKLCYRGAISLSSILRQ-----SPLHQLALKVEPRGTIYIRMRHTDPLALYKRRGLPSLRAGYPTLFGADLETVV----NRESKNAPGSAPVPIVLRRCVEEVERRGLDIIGLYRLCGSATKKRLLREAFERNSRAVELTPEHVPDINVITGVLKDYLRELPEPLFTRCLFQMTVDALAVCLPDDPEGNAKLMLSILDCLPRANRATLVFLLDHLSLVVSNSERNKMSAQALATVMGPPLMLHS---ASAQPGADIDHAQPIAVLKYLLQIW 1144
BLAST of Rho GTPase-activating protein vs. UniProt/SwissProt
Match: sp|Q61CA4|SYD1_CAEBR (Rho GTPase-activating protein syd-1 OS=Caenorhabditis briggsae OX=6238 GN=syd-1 PE=3 SV=2) HSP 1 Score: 222.246 bits (565), Expect = 4.748e-58 Identity = 131/395 (33.16%), Postives = 216/395 (54.68%), Query Frame = 1
Query: 2620 PVLASGGHPQRNKSATGYVSGMLVIHVVAGIGLN---SSQTVVRDLYCVLEIDSVRRARSMIRTSTEIFEWDEIFELDVEDNDWLAFLFYQWDPRNRHRLCFYGNVALRQLIERFRHSYTNSEKL-ALYLEPKGVLFIELLYLKINEVFQRFKMPVNTDALFGVPLEVLVSRDLNRQGETDGQECRVPIIVRRCTEEVEKRGLDVVSIYRLSGAVKLKIRIREMLEQDVIAADLSADTVPDIHAITAVLRDFLRELPEPLFTNALYRMILDALQVSLPGDNYAGAKLMLNILDCLPIVNQDTILHLLDHLKRVSSRSEVNKMTNEALAASLGPVLFF--------PSPEEAXXXXXXXXXXXXQAQTLLYILNIWPDESDHQYHSRDSKSKEPQK 3768
P+ A+G ++ + ++G+L +H++ G GL + + ++YCVLE+D RAR+ + T + F+W E F +DV + F Y W P+ RH+LC G++ +L+E F N +++ AL LEP+G L + + + + VF+R P + +FGVPL LV R+ PI++ R +E+EKRG+D+ +Y L G+V+ K +R LE + + DL+A+ +PD + I +++DFLRELPEPL + ++ M+L+A V+LP D A L+L I+DCL + ++ +L +LDHL + S N +T L+ P+LFF + +K LD + + +L IL+IWP + + S DS + QK
Sbjct: 570 PLRAAGPGINVDRLSVSSLTGILYVHILEGRGLKIPEKQKGLTEEMYCVLEVDEQHRARTGVSTIEQKFKWRETFHIDVVNATVSNFFVYSWHPQFRHKLCHKGSL---KLLEAFVVDQLNDDRVFALNLEPRGQLIVRIGFHDLQAVFRRTVNP-RLNGVFGVPLGRLVQRERRD----------TPIVLTRLIQEIEKRGVDLSGLYVLCGSVEKKKMLRAQLESNPLGTDLNAENIPDTNVIACLIKDFLRELPEPLISPQIHGMLLEAATVALPNDVQANRTLVLKIIDCLQLSAKNCLLLVLDHLSTILCSSPHNGLTPTRLSLIFAPLLFFCLDAISPYTTSPTSKMAAVRSLDMNQASSSLQMILSIWPSRVNSESGS-DSPATSGQK 949
BLAST of Rho GTPase-activating protein vs. UniProt/SwissProt
Match: sp|Q86NH1|SYD1_CAEEL (Rho GTPase-activating protein syd-1 OS=Caenorhabditis elegans OX=6239 GN=syd-1 PE=2 SV=1) HSP 1 Score: 216.083 bits (549), Expect = 5.923e-56 Identity = 131/395 (33.16%), Postives = 215/395 (54.43%), Query Frame = 1
Query: 2620 PVLASGGHPQRNKSATGYVSGMLVIHVVAGIGLN---SSQTVVRDLYCVLEIDSVRRARSMIRTSTEIFEWDEIFELDVEDNDWLAFLFYQWDPRNRHRLCFYGNVALRQLIERFRHSYTNSEKL-ALYLEPKGVLFIELLYLKINEVFQRFKMPVNTDALFGVPLEVLVSRDLNRQGETDGQECRVPIIVRRCTEEVEKRGLDVVSIYRLSGAVKLKIRIREMLEQDVIAADLSADTVPDIHAITAVLRDFLRELPEPLFTNALYRMILDALQVSLPGDNYAGAKLMLNILDCLPIVNQDTILHLLDHLKRVSSRSEVNKMTNEALAASLGPVLFFP----SP----EEAXXXXXXXXXXXXQAQTLLYILNIWPDESDHQYHSRDSKSKEPQK 3768
P+ A+G ++ + ++G+L +H+V G GL + + ++YCVLE+D RAR+ + T + F+W E F +DV + F Y W P+ RH+LC G++ +L+E F N +++ AL LEP+G L + + + + VF+R P + +FG+ L LV R+ PI++ R +E+EKRG+D +Y L G+V+ K +R LE + + +L+A+++PD + I +++DFLRELPEPL + ++ M+L+A V+LP D L+L I+DCL + ++ +L +LDHL V S N +T L+ P+LFF SP +K LD + + +L IL+IWP + + S DS + QK
Sbjct: 596 PLRAAGPGINVDRLSVSSLTGILYVHIVEGRGLKIPEKQKGLTEEMYCVLEVDEQHRARTGVSTIEQKFKWRETFHIDVVNATVSNFFVYSWHPQFRHKLCHKGSL---KLLEAFVVDQLNDDRVFALNLEPRGQLIVRIGFHDLQAVFRRTVNP-RLNGVFGISLSRLVQRERRD----------TPIVLTRLIQEIEKRGVDYSGLYVLCGSVEKKKMLRAELESNPLGTELAAESIPDTNVIACLIKDFLRELPEPLISPQIHGMLLEAASVALPNDVQTNRHLVLKIIDCLQLSAKNCLLLVLDHLSTVLCSSPHNGLTPTRLSLIFAPLLFFCLDTFSPYTISPTSKMAAVRTLDINQASSSLQMILSIWPSRVNSESGS-DSPATTCQK 975
BLAST of Rho GTPase-activating protein vs. UniProt/SwissProt
Match: sp|Q5VT97|SYDE2_HUMAN (Rho GTPase-activating protein SYDE2 OS=Homo sapiens OX=9606 GN=SYDE2 PE=1 SV=2) HSP 1 Score: 211.46 bits (537), Expect = 5.150e-54 Identity = 124/370 (33.51%), Postives = 203/370 (54.86%), Query Frame = 1
Query: 2671 YVSGMLVIHVVAGIGLNSSQTVVRDLYCVLEIDSVRRARSMIRTS-TEIFEWDEIFELDVEDNDWLAFLFYQWDPRNR-HRLCFYGNVALRQLIERFRHSYTNSEKLALYLEPKGVLFIELLYLKINEVFQRFKMPVNTDAL-FGVPLEVLVSRDLNRQGETDGQECRVPIIVRRCTEEVEKRGLDVVSIYRLSGAVKLKIRIREMLEQDVIAADLSADTVPDIHAITAVLRDFLRELPEPLFTNALYRMILDALQVSL-----------PGDNYAGAKLMLNILDCLPIVNQDTILHLLDHLKRVSSRSEVNKMTNEALAASLGPVLFFPSPEEAXXXXXXXXXXXXQA---------QTLLYILNIWP 3711
Y+SG++ +H L + +D++C +++DSV +AR+ + T T + D F +++E+ L + + W+P R +R+C +G V L L FR T + +LA+ LEP+G++++++ ++ E + +N + + FGV ++ +V E + VP+++++C E+EKRG VV +YRL G+ +K +RE E+D A L + PDI+ IT VL+D+LRELP PL T LY +LDA+ S PGD +K +++LDCLP + + T+ LLDHLK V+S EVNKMT + LA GPVL E + ++ D ++ A + L Y+L +WP
Sbjct: 677 YISGLMSVHFYGAEDLKPPRIDSKDVFCAIQVDSVNKARTALLTCRTTFLDMDHTFNIEIENAQHLKLVVFSWEPTPRKNRVCCHGTVVLPTL---FR--VTKTHQLAVKLEPRGLIYVKVTLMEQWE-NSLHGLDINQEPIIFGVDIQKVV--------EKENIGLMVPLLIQKCIMEIEKRGCQVVGLYRLCGSAAVKKELREAFERDSKAVGLCENQYPDINVITGVLKDYLRELPSPLITKQLYEAVLDAMAKSPLKMSSNGCENDPGD----SKYTVDLLDCLPEIEKATLKMLLDHLKLVASYHEVNKMTCQNLAVCFGPVLLSQRQEPSTHNNRVFTDSEELASALDFKKHIEVLHYLLQLWP 1028
BLAST of Rho GTPase-activating protein vs. UniProt/SwissProt
Match: sp|D3ZZN9|SYDE1_RAT (Rho GTPase-activating protein SYDE1 OS=Rattus norvegicus OX=10116 GN=Syde1 PE=1 SV=1) HSP 1 Score: 194.126 bits (492), Expect = 6.997e-50 Identity = 128/356 (35.96%), Postives = 189/356 (53.09%), Query Frame = 1
Query: 2680 GMLVIHVVAGIGLNSSQTVV-RDLYCVLEIDSVRRARSM-IRTSTEIFEWDEIFELDVEDNDWLAFLFYQWDPR-NRHRLCFYGNVALRQLIERFRHSYTNSEKLALYLEPKGVLFIELLYLKINEVFQRFKMPVNTDA-LFGVPLEVLVSRDLNRQGETDGQECRVPIIVRRCTEEVEKRGLDVVSIYRLSGAVKLKIRIREMLEQDVIAADLSADTVPDIHAITAVLRDFLRELPEPLFTNALYRMILDALQVSLPGDNYAGAKLMLNILDCLPIVNQDTILHLLDHLKRVSSRSEVNKMTNEALAASLGPVLFFPSPEEAXXXXXXXXXXXXQA-------QTLLYILNIWPD 3714
G L +H+ GL + RDL C+L++D V RAR+ +R+ + D F L++E L L WDP RHR C G V L + FR +++LA+ LEP+G+L+ +L + E P + +FG+PL++LV R+ ++ GQ VP+I+R+C ++E RGL VV +YRL G+ +K +R+ EQD A LS D PDI+ IT +L+D+LRELP PL T LY+++L+A+ P G + +L CLP V + T+ LLDHL+ VSS N+MT + LA GPVL ++ + A + L Y+L WPD
Sbjct: 266 GRLSLHLYGLGGLRPTPGATPRDLCCLLQVDGVARARTGPLRSGPDFLRLDHTFHLELEAARLLRALVLAWDPGVRRHRPCAQGTVLLPTI---FRG--CQAQQLAVRLEPQGLLYAKLTLSEQQEA------PATVEPRVFGLPLQLLVERE-----QSPGQ---VPLIIRKCVGQIECRGLRVVGLYRLCGSAAVKKELRDAFEQDSAAVCLSEDVYPDINVITGILKDYLRELPTPLITQPLYQVVLEAMAQGHPSRASLGPEGTRGLLSCLPDVERATLTLLLDHLRLVSSFHTHNRMTPQNLAVCFGPVLLPARQTPSRTRLRGSGPGVSSAVDFKRHIEVLHYLLQSWPD 602
BLAST of Rho GTPase-activating protein vs. TrEMBL
Match: A0A267G9H2 (Rho-GAP domain-containing protein OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig014851g2 PE=4 SV=1) HSP 1 Score: 388.652 bits (997), Expect = 2.670e-117 Identity = 198/381 (51.97%), Postives = 260/381 (68.24%), Query Frame = 1
Query: 2566 VSRLDPNEFRKIQTEQWPPVLASGGHPQRNKSATGYVSGMLVIHVVAGIGLNSSQTVVRDLYCVLEIDSVRRARSMIRTSTEIFEWDEIFELDVEDNDWLAFLFYQWDPRNRHRLCFYGNVALRQLIERFRHSYTNSEKLALYLEPKGVLFIELLYLKINEVFQRFKMPVNTDALFGVPLEVLVSRDLNRQGETDGQECRVPIIVRRCTEEVEKRGLDVVSIYRLSGAVKLKIRIREMLEQDVIAADLSADTVPDIHAITAVLRDFLRELPEPLFTNALYRMILDALQVSLPGDNYAGAKLMLNILDCLPIVNQDTILHLLDHLKRVSSRSEVNKMTNEALAASLGPVLFFPSPEEAXXXXXXXXXXXXQAQTLLYILNIW 3708
RL +EFR +++ L G HP + G+L +HVVAG GL++ +RDLYC+LE+DSVR ARS+IRTSTE F WDE F+L L FL YQWDP N+HRLCF+G+V L L FRH SE++AL +EPKG L+ EL I+EV R + P ++FGVP+++LV R E GQ+ VP++V++C +EVE+RGLD+ IYRL G+ K KI +RE E+ DLSAD VPDIHA+T +L+DF+RELPEPLFTNALYRM+LDAL V +PGD GAKLML+ILDCLP VNQ+T++ +LDHLKRV+ RS+ NKMT + LA LGP+L +PSP+ A+ ++ S L + + L YIL+IW
Sbjct: 104 AGRLSLHEFRPCPSDRSARSLGPG-HP-------AGIDGVLRVHVVAGTGLHAPVVALRDLYCLLELDSVRMARSLIRTSTECFHWDEQFDLFAAGARGLGFLLYQWDPSNKHRLCFHGSVNLVSLAASFRHRCIRSERIALGMEPKGCLYFELTCYSISEVMCRTQSPRMHSSIFGVPIDILVRR------EKSGQQ--VPLLVQKCIDEVERRGLDIPGIYRLCGSNKSKISLREAFERRPGKVDLSADKVPDIHAVTGLLKDFVRELPEPLFTNALYRMLLDALAVEIPGDPRGGAKLMLSILDCLPPVNQETLVAILDHLKRVALRSDANKMTLDQLATCLGPLLLYPSPDSARIMEASFLQLGRMSHVLQYILDIW 468
BLAST of Rho GTPase-activating protein vs. TrEMBL
Match: A0A267DD13 (Rho-GAP domain-containing protein OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig033009g1 PE=4 SV=1) HSP 1 Score: 388.652 bits (997), Expect = 2.842e-117 Identity = 198/381 (51.97%), Postives = 260/381 (68.24%), Query Frame = 1
Query: 2566 VSRLDPNEFRKIQTEQWPPVLASGGHPQRNKSATGYVSGMLVIHVVAGIGLNSSQTVVRDLYCVLEIDSVRRARSMIRTSTEIFEWDEIFELDVEDNDWLAFLFYQWDPRNRHRLCFYGNVALRQLIERFRHSYTNSEKLALYLEPKGVLFIELLYLKINEVFQRFKMPVNTDALFGVPLEVLVSRDLNRQGETDGQECRVPIIVRRCTEEVEKRGLDVVSIYRLSGAVKLKIRIREMLEQDVIAADLSADTVPDIHAITAVLRDFLRELPEPLFTNALYRMILDALQVSLPGDNYAGAKLMLNILDCLPIVNQDTILHLLDHLKRVSSRSEVNKMTNEALAASLGPVLFFPSPEEAXXXXXXXXXXXXQAQTLLYILNIW 3708
RL +EFR +++ L G HP + G+L +HVVAG GL++ +RDLYC+LE+DSVR ARS+IRTSTE F WDE F+L L FL YQWDP N+HRLCF+G+V L L FRH SE++AL +EPKG L+ EL I+EV R + P ++FGVP+++LV R E GQ+ VP++V++C +EVE+RGLD+ IYRL G+ K KI +RE E+ DLSAD VPDIHA+T +L+DF+RELPEPLFTNALYRM+LDAL V +PGD GAKLML+ILDCLP VNQ+T++ +LDHLKRV+ RS+ NKMT + LA LGP+L +PSP+ A+ ++ S L + + L YIL+IW
Sbjct: 106 AGRLSLHEFRPCPSDRSARSLGPG-HP-------AGIDGVLRVHVVAGTGLHAPVVALRDLYCLLELDSVRMARSLIRTSTECFHWDEQFDLFAAGARGLGFLLYQWDPSNKHRLCFHGSVNLVSLAASFRHRCIRSERIALGMEPKGCLYFELTCYSISEVMCRTQSPRMHSSIFGVPIDILVRR------EKSGQQ--VPLLVQKCIDEVERRGLDIPGIYRLCGSNKSKISLREAFERRPGKVDLSADKVPDIHAVTGLLKDFVRELPEPLFTNALYRMLLDALAVEIPGDPRGGAKLMLSILDCLPPVNQETLVAILDHLKRVALRSDANKMTLDQLATCLGPLLLYPSPDSARIMEASFLQLGRMSHVLQYILDIW 470
BLAST of Rho GTPase-activating protein vs. TrEMBL
Match: A0A267DXS3 (Rho-GAP domain-containing protein OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig014851g1 PE=4 SV=1) HSP 1 Score: 390.193 bits (1001), Expect = 1.968e-116 Identity = 198/381 (51.97%), Postives = 260/381 (68.24%), Query Frame = 1
Query: 2566 VSRLDPNEFRKIQTEQWPPVLASGGHPQRNKSATGYVSGMLVIHVVAGIGLNSSQTVVRDLYCVLEIDSVRRARSMIRTSTEIFEWDEIFELDVEDNDWLAFLFYQWDPRNRHRLCFYGNVALRQLIERFRHSYTNSEKLALYLEPKGVLFIELLYLKINEVFQRFKMPVNTDALFGVPLEVLVSRDLNRQGETDGQECRVPIIVRRCTEEVEKRGLDVVSIYRLSGAVKLKIRIREMLEQDVIAADLSADTVPDIHAITAVLRDFLRELPEPLFTNALYRMILDALQVSLPGDNYAGAKLMLNILDCLPIVNQDTILHLLDHLKRVSSRSEVNKMTNEALAASLGPVLFFPSPEEAXXXXXXXXXXXXQAQTLLYILNIW 3708
RL +EFR +++ L G HP + G+L +HVVAG GL++ +RDLYC+LE+DSVR ARS+IRTSTE F WDE F+L L FL YQWDP N+HRLCF+G+V L L FRH SE++AL +EPKG L+ EL I+EV R + P ++FGVP+++LV R E GQ+ VP++V++C +EVE+RGLD+ IYRL G+ K KI +RE E+ DLSAD VPDIHA+T +L+DF+RELPEPLFTNALYRM+LDAL V +PGD GAKLML+ILDCLP VNQ+T++ +LDHLKRV+ RS+ NKMT + LA LGP+L +PSP+ A+ ++ S L + + L YIL+IW
Sbjct: 214 AGRLSLHEFRPCPSDRSARSLGPG-HPAG-------IDGVLRVHVVAGTGLHAPVVALRDLYCLLELDSVRMARSLIRTSTECFHWDEQFDLFAAGARGLGFLLYQWDPSNKHRLCFHGSVNLVSLAASFRHRCIRSERIALGMEPKGCLYFELTCYSISEVMCRTQSPRMHSSIFGVPIDILVRR------EKSGQQ--VPLLVQKCIDEVERRGLDIPGIYRLCGSNKSKISLREAFERRPGKVDLSADKVPDIHAVTGLLKDFVRELPEPLFTNALYRMLLDALAVEIPGDPRGGAKLMLSILDCLPPVNQETLVAILDHLKRVALRSDANKMTLDQLATCLGPLLLYPSPDSARIMEASFLQLGRMSHVLQYILDIW 578
BLAST of Rho GTPase-activating protein vs. TrEMBL
Match: A0A267GUS3 (Uncharacterized protein OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig013375g2 PE=4 SV=1) HSP 1 Score: 393.66 bits (1010), Expect = 2.242e-113 Identity = 191/345 (55.36%), Postives = 253/345 (73.33%), Query Frame = 1
Query: 2674 VSGMLVIHVVAGIGLNSSQTVVRDLYCVLEIDSVRRARSMIRTSTEIFEWDEIFELDVEDNDWLAFLFYQWDPRNRHRLCFYGNVALRQLIERFRHSYTNSEKLALYLEPKGVLFIELLYLKINEVFQRFKMPVNTDALFGVPLEVLVSRDLNRQGETDGQECRVPIIVRRCTEEVEKRGLDVVSIYRLSGAVKLKIRIREMLEQDVIAADLSADTVPDIHAITAVLRDFLRELPEPLFTNALYRMILDALQVSLPGDNYAGAKLMLNILDCLPIVNQDTILHLLDHLKRVSSRSEVNKMTNEALAASLGPVLFFPSPEEAXXXXXXXXXXXXQAQTLLYILNIW 3708
V G+L +HV+AG+GL+SSQ+++RDLYC+LE+DS R ARSMIRTST+ FEWDE F++ L FL YQWDPR++HRLCFYGNV L L+ FR Y SEK+AL LEPKG L+ E+ + +++EVF R P +FGVPL++L R+ + +P++VR+C +EVE+RGL+V IYRL G+ + K +R+ L++ AD+SA+ VPDIHA+T VL+DFL ELPEPLFTNALYRM+LDALQV LPGD GAKLML+ILDCLP NQ+T+L LLDHLKRV+++++VNKMT LA LGP+L FPSP+ A+++D +L + + L YIL IW
Sbjct: 601 VDGVLRVHVIAGVGLHSSQSLLRDLYCLLELDSTRVARSMIRTSTDCFEWDEQFDIFCSGARGLGFLLYQWDPRSKHRLCFYGNVNLVSLLSSFRQRYIKSEKIALSLEPKGQLYFEVTFAEVHEVFCR--EPAQRSGVFGVPLDLLARRE----------KSSIPMLVRKCIDEVERRGLEVAGIYRLCGSSRNKQPVRDALDRSAAEADVSAEKVPDIHAVTGVLKDFLCELPEPLFTNALYRMMLDALQVRLPGDPKGGAKLMLSILDCLPPANQETLLLLLDHLKRVAAKADVNKMTTGQLATCLGPLLLFPSPDAARQMDPEILRLGRMSDVLKYILEIW 933
BLAST of Rho GTPase-activating protein vs. TrEMBL
Match: A0A267F832 (Uncharacterized protein OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig013375g1 PE=4 SV=1) HSP 1 Score: 390.963 bits (1003), Expect = 1.766e-112 Identity = 191/345 (55.36%), Postives = 252/345 (73.04%), Query Frame = 1
Query: 2674 VSGMLVIHVVAGIGLNSSQTVVRDLYCVLEIDSVRRARSMIRTSTEIFEWDEIFELDVEDNDWLAFLFYQWDPRNRHRLCFYGNVALRQLIERFRHSYTNSEKLALYLEPKGVLFIELLYLKINEVFQRFKMPVNTDALFGVPLEVLVSRDLNRQGETDGQECRVPIIVRRCTEEVEKRGLDVVSIYRLSGAVKLKIRIREMLEQDVIAADLSADTVPDIHAITAVLRDFLRELPEPLFTNALYRMILDALQVSLPGDNYAGAKLMLNILDCLPIVNQDTILHLLDHLKRVSSRSEVNKMTNEALAASLGPVLFFPSPEEAXXXXXXXXXXXXQAQTLLYILNIW 3708
V G+L +HV+AG+GL+SSQ+++RDLYC+LE+DS R ARSMIRTST+ FEWDE F++ L FL YQWDPR++HRLCFYGNV L L+ FR Y SEK+AL LEPKG L+ E+ + ++ +VF R P +FGVPL++L R+ + +P++VR+C +EVE+RGL+V IYRL G+ + K +RE L++ AD+SA+ VPDIHA+T VL+DFL ELPEPLFTNALYRM+LDALQV LPGD GAKLML+ILDCLP NQ+T+L LLDHLKRV+++++VNKMT LA LGP+L FPSP+ A+++D +L + + L YIL IW
Sbjct: 601 VDGVLRVHVIAGVGLHSSQSLLRDLYCLLELDSTRVARSMIRTSTDCFEWDEQFDIFCSGARGLGFLLYQWDPRSKHRLCFYGNVNLVSLLSSFRQRYIKSEKIALSLEPKGQLYFEVTFAEVPDVFCR--EPAQRIGVFGVPLDLLARRE----------KSSIPMLVRKCIDEVERRGLEVAGIYRLCGSSRNKQPVREALDRSAAEADVSAEKVPDIHAVTGVLKDFLCELPEPLFTNALYRMMLDALQVRLPGDPKGGAKLMLSILDCLPPANQETLLLLLDHLKRVAAKADVNKMTTGQLATCLGPLLLFPSPDAARQMDPEILRLDRMSDVLKYILEIW 933
BLAST of Rho GTPase-activating protein vs. Ensembl Cavefish
Match: SYDE2 (synapse defective Rho GTPase homolog 2 [Source:NCBI gene;Acc:103025539]) HSP 1 Score: 203.371 bits (516), Expect = 3.169e-52 Identity = 129/375 (34.40%), Postives = 201/375 (53.60%), Query Frame = 1
Query: 2662 ATGYVSGMLVIHVVAGIGLNSSQTVVRDLYCVLEIDSVRRARSMIRTS-TEIFEWDEIFELDVEDNDWLAFLFYQWD--PRNRHRLCFYGNVALRQLIERFRHSYTNSEKLALYLEPKGVLFIELLYLK--INEVFQRFKMPVNTDALFGVPLEVLVSRDLNRQGETDGQECRVPIIVRRCTEEVEKRGLDVVSIYRLSGAVKLKIRIREMLEQDVIAADLSADTVPDIHAITAVLRDFLRELPEPLFTNALYRMILDA-----LQVSLPG--DNYAGAKLMLNILDCLPIVNQDTILHLLDHLKRVSSRSEVNKMTNEALAASLGPVLF-------------FPSPEEAXXXXXXXXXXXXQAQTLLYILNIWP 3711
T Y+SG++ +H GL + R +YC +++DSV +AR+ + T T + D F +++E+ L + W+ PR R+R+C +G V L L FR + T + +LA+ LEP+G+++++L ++ N + +FGV +V R+ G VP+I+ +C E+E+RG VV +YRL G+ +K +RE E+D A +LS PDI+ IT VL+D+LRELP PL + LY ++D+ L + G ++ A ++ +++L+ LP V + T+ LLDHLKRV+S EVNKMT + LA GPVL F EE S L KK + L Y+L +WP
Sbjct: 1027 CTAYISGLMSLHFYGAEGLKPPRADSRHVYCAIQVDSVNKARTALLTCRTAFLDMDHTFNIELENAQHLKLALFSWEAVPR-RNRVCCHGTVVLPPL---FR-TATRTHQLAVRLEPRGIIYVKLGLMEQWKNSLRGPDSEREGEANVFGVEAARVVERE--------GAGLMVPLIIEKCITEIERRGCQVVGLYRLCGSAAVKKELREAFERDSHAIELSESNYPDINVITGVLKDYLRELPFPLISKPLYEAVIDSMAKRPLLIGSGGCENDPAESEHTVSLLETLPEVEKMTLRKLLDHLKRVASHHEVNKMTCQNLAVCFGPVLLSQRQDASCHSNRVFVDSEE----LASALHFKKHIEVLHYLLQLWP 1384
BLAST of Rho GTPase-activating protein vs. Ensembl Cavefish
Match: SYDE1 (synapse defective Rho GTPase homolog 1 [Source:HGNC Symbol;Acc:HGNC:25824]) HSP 1 Score: 144.436 bits (363), Expect = 2.738e-36 Identity = 88/257 (34.24%), Postives = 137/257 (53.31%), Query Frame = 1
Query: 2977 EKLALYLEPKGVLFIELLYLKINEVFQRFKMPVNTDALFGVPLEVLVSRDLNRQGETDGQECRVPIIVRRCTEEVEKRGLDVVSIYRLSGAVKLKIRIREMLEQDVIAADLSADTVPDIHAITAVLRDFLRELPEPLFTNALYRMILDALQVSLPGDN---YAGAKLMLNILDCLPIVNQDTILHLLDHLKRVSSRSEVNKMTNEALAASLGPVLFFPSPEEAXXXXXXXXXXXXQA---------QTLLYILNIWP 3711
++L + LEP+G+L+++L L+ E + A+FGV L LV E + + +VP+I+++C E+E RGL VV +YRL G+ +K +R+ E+D L+ + PDI+ IT +L+D+LRELP L T LY ++L+A+ V G N ++ + +L CLP + T+ LLDHL V+S S+ N MT + LA GPVL P+ E + A + L Y+L +WP
Sbjct: 47 QQLCVKLEPRGLLYVKLTLLEQWEAPSPRLSELPPPAVFGVELRRLV--------EKEQHQLKVPLIIQKCVAEIETRGLKVVGLYRLCGSAAVKKELRDAFEKDSAVVTLNEELYPDINVITGILKDYLRELPSALITRTLYEVVLEAMCVRPAGRNDNDTQRSQSTVALLHCLPEPERATLSFLLDHLSLVASFSDCNLMTCQNLAVCFGPVLLTPTQESWRAGLPGSSSEGFGASAVDFKRHIEALHYLLQLWP 295
BLAST of Rho GTPase-activating protein vs. Ensembl Cavefish
Match: bcr (BCR activator of RhoGEF and GTPase [Source:NCBI gene;Acc:103040765]) HSP 1 Score: 134.42 bits (337), Expect = 3.993e-31 Identity = 107/366 (29.23%), Postives = 174/366 (47.54%), Query Frame = 1
Query: 2686 LVIHVVAGIGLNSSQTVVRDLYCVLEIDS----VRRARSMIRTSTEIFEWDEIFELDVEDNDWLAFLFYQW----------DPRNRHRLCFYGNVALR-QLIERFRHSYTNSEKLALYLEPKGVLFIELLYLKINEVFQRFKMPVNTDA-LFGVPLEVLVSRDLNRQGETDGQECRVPIIVRRCTEEVEKRGLDVVSIYRLSGAVKLKIRIREMLEQDVIAADLSADTVPDIHAITAVLRDFLRELPEPLFTNALYRMILDALQVSLPGDNYAGAKLMLNILDCLPIVNQDTILHLLDHLKRVSSRSEVNKMTNEALAASLGPVLFFPSPEEA----------XXXXXXXXXXXXQAQTLLYILNI 3705
++IH +G+ Q++ +LYC LE+DS V +A++ + T +W+E FE+++E + L L Y+ D + R+ G + L Q+++ + + P + ++L + F +MP A +FGV + + R + +VP IVR+C EE+E+RG++ V IYR+SG ++ + + + + D++AI L+ + RELPEPLFT+ LY + +S D+ A MLN+L LP N T L LLDHLKRV+ + VNKM+ LA GP L P+ +++ D L+ Q Q LLY L +
Sbjct: 1000 VIIHSASGL----KQSL--NLYCTLEVDSFGFFVNKAKTRVYRYTTEPKWNEEFEIELEGSQMLRLLCYEKSYNKSKTNKEDADSTDRIIGKGQIPLDPQMLQ--------GKDWQRTVIPMNGIEVKLSMKFTSREFSLKRMPSCKQAGVFGVKISTVTKR----------ERSKVPYIVRQCLEEIERRGMEEVGIYRVSGVATDIQALKTAFDTNNKDVSVMMSEM-DVNAIAGTLKLYFRELPEPLFTDELYPNFAGGIALS---DSVAKESCMLNLLLSLPEPNLVTFLFLLDHLKRVAEKECVNKMSLHNLATVFGPTLLRPAEKDSKIPTNPTQPITMGDSWSLEVMSQVQVLLYFLQL 1337
BLAST of Rho GTPase-activating protein vs. Ensembl Cavefish
Match: bcr (BCR activator of RhoGEF and GTPase [Source:NCBI gene;Acc:103040765]) HSP 1 Score: 134.035 bits (336), Expect = 5.696e-31 Identity = 107/366 (29.23%), Postives = 174/366 (47.54%), Query Frame = 1
Query: 2686 LVIHVVAGIGLNSSQTVVRDLYCVLEIDS----VRRARSMIRTSTEIFEWDEIFELDVEDNDWLAFLFYQW----------DPRNRHRLCFYGNVALR-QLIERFRHSYTNSEKLALYLEPKGVLFIELLYLKINEVFQRFKMPVNTDA-LFGVPLEVLVSRDLNRQGETDGQECRVPIIVRRCTEEVEKRGLDVVSIYRLSGAVKLKIRIREMLEQDVIAADLSADTVPDIHAITAVLRDFLRELPEPLFTNALYRMILDALQVSLPGDNYAGAKLMLNILDCLPIVNQDTILHLLDHLKRVSSRSEVNKMTNEALAASLGPVLFFPSPEEA----------XXXXXXXXXXXXQAQTLLYILNI 3705
++IH +G+ Q++ +LYC LE+DS V +A++ + T +W+E FE+++E + L L Y+ D + R+ G + L Q+++ + + P + ++L + F +MP A +FGV + + R + +VP IVR+C EE+E+RG++ V IYR+SG ++ + + + + D++AI L+ + RELPEPLFT+ LY + +S D+ A MLN+L LP N T L LLDHLKRV+ + VNKM+ LA GP L P+ +++ D L+ Q Q LLY L +
Sbjct: 905 VIIHSASGL----KQSL--NLYCTLEVDSFGFFVNKAKTRVYRYTTEPKWNEEFEIELEGSQMLRLLCYEKSYNKSKTNKEDADSTDRIIGKGQIPLDPQMLQ--------GKDWQRTVIPMNGIEVKLSMKFTSREFSLKRMPSCKQAGVFGVKISTVTKR----------ERSKVPYIVRQCLEEIERRGMEEVGIYRVSGVATDIQALKTAFDTNNKDVSVMMSEM-DVNAIAGTLKLYFRELPEPLFTDELYPNFAGGIALS---DSVAKESCMLNLLLSLPEPNLVTFLFLLDHLKRVAEKECVNKMSLHNLATVFGPTLLRPAEKDSKIPTNPTQPITMGDSWSLEVMSQVQVLLYFLQL 1242
BLAST of Rho GTPase-activating protein vs. Ensembl Cavefish
Match: ABR (ABR activator of RhoGEF and GTPase [Source:NCBI gene;Acc:103046632]) HSP 1 Score: 132.88 bits (333), Expect = 1.191e-30 Identity = 108/370 (29.19%), Postives = 174/370 (47.03%), Query Frame = 1
Query: 2680 GMLVIHVVAGIGLNSSQTVVRDLYCVLEIDS----VRRARSMIRTSTEIFEWDEIFELDVEDNDWLAFLFYQWDPRNRHRLCFYGNVALRQLIERFRHSYTNSEKLALYLEPKGVLF--IELLYLKINEVFQRFKMPVNT-------------DALFGVPLEVLVSRDLNRQGETDGQECRVPIIVRRCTEEVEKRGLDVVSIYRLSGAVKLKIRIREMLEQD-----VIAADLSADTVPDIHAITAVLRDFLRELPEPLFTNALYRMILDALQVSLPGDNYAGAKLMLNILDCLPIVNQDTILHLLDHLKRVSSRSEVNKMTNEALAASLGPVLFFPSPEEAXXXXXXXXX------XXXQAQTLLYIL 3699
G L + V + G S +LYC LE+DS V +A++ + T +W+E FE+++E + L L Y+ ++ +L N + +++ + + + L+P+ V + +++N + F M + +FGV + V+ R + +VP IVR+C EEVEKRG+D V IYR+SG ++ + + V+ +D+ DI+AI L+ + RELPEPL T+ LY ++ + +S P A M+++L LP N T L LL+HLKRV+ + +NKM+ LA GP L PS E K ++ Q Q LLY L
Sbjct: 815 GFLHVIVHSATGFKESA----NLYCTLEVDSFGYFVSKAKTRVFRDTAEPQWNEEFEIELEGSQCLRILCYE-KCYDKSKLNKDDNEIVDKIMGKGQ----------VQLDPQTVQSKNWHVDVIEMNGIKVEFSMKFTSRDLSLKRTPSKKQSGVFGVKISVVTKR----------ERSKVPYIVRQCIEEVEKRGIDEVGIYRISGVATDIQALKAAFDTNTKDILVMLSDM------DINAIAGTLKLYFRELPEPLLTDRLYPAFMEGIALSDPA---AKENCMMHLLRSLPDPNLITFLTLLEHLKRVAEKEPINKMSLHNLATVFGPTLLRPSESETSKPHITMASDIWSHDVMAQVQVLLYYL 1150
BLAST of Rho GTPase-activating protein vs. Ensembl Sea Lamprey
Match: chn2 (chimerin 2 [Source:ZFIN;Acc:ZDB-GENE-091020-5]) HSP 1 Score: 91.6633 bits (226), Expect = 3.861e-20 Identity = 60/190 (31.58%), Postives = 92/190 (48.42%), Query Frame = 1
Query: 3070 PVNTDALFGVPLEVLVSRDLNRQGETDGQECRVPIIVRRCTEEVEKRGLDVVSIYRLSGAVKLKIRIREMLEQDVIAADLSADTVPDIHAITAVLRDFLRELPEPLFTNALYRMILDALQVSLPGDNYAGAKLMLNILDCLPIVNQDTILHLLDHL--KRVSSRSEVNKMTNEALAASLGPVLFFPSPEE 3633
P +FG L LV R+P++V C E+E RGL +YR+SG L +R +++ AD+SA D++ IT L+ + RELP PL T Y ++A +VS P + + L LP + DT+ L+ HL +RVS + + N M++E L+ GP L P ++
Sbjct: 103 PRRLPKVFGCDLTALVK----------AHRGRLPMVVEMCIGEIEARGLKSEGLYRVSGVSDLVEEVRTAFDKEGEKADISAKAYEDVNVITGALKLYFRELPTPLVTYQAYPHFVEAAKVSDPAERLEQLR---RALQTLPPAHYDTLHCLMAHLHRRRVSQQEKHNLMSSENLSIVFGPTLMRPHEQD 279
BLAST of Rho GTPase-activating protein vs. Ensembl Sea Lamprey
Match: ENSPMAT00000004676.1 (pep scaffold:Pmarinus_7.0:GL476377:189826:224778:-1 gene:ENSPMAG00000004196.1 transcript:ENSPMAT00000004676.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 92.0485 bits (227), Expect = 3.411e-19 Identity = 58/185 (31.35%), Postives = 93/185 (50.27%), Query Frame = 1
Query: 3082 DALFGVPLEVLVSRDLNRQGETDGQECRVPIIVRRCTEEVEKRGLDVVSIYRLSGAVKLKIRIREMLEQDVIAADLSADTVPDIHAITAVLRDFLRELPEPLFTNALYRMILDALQVSLPGDNYAGAKLMLNILDCLPIVNQDTILHLLDHLKRVSSRSEVNKMTNEALAASLGPVLFFPSPEEA 3636
+ +FG PL +L R + VP V+ E V+KRGL + IYR+SG + ++R +++ + L DIH IT L+ F RELPEPLF + + A+++ D+ + + LP N+DT+ L +HLK+V + + N+MT +++A GP L P E +
Sbjct: 417 EQVFGCPLAMLCER----------ENTTVPKFVQLSIETVDKRGLCIDGIYRVSGNLATIQKLRFLVDHEE-KVSLDESHWEDIHVITGALKMFFRELPEPLFPFNQFDPFISAIKLQ---DSREKLTKIKEQVQKLPKPNKDTMRALFEHLKKVIACGDANRMTTQSVAIVFGPTLLRPENESS 587
BLAST of Rho GTPase-activating protein vs. Ensembl Sea Lamprey
Match: ENSPMAT00000004494.1 (pep scaffold:Pmarinus_7.0:GL476606:246273:272967:-1 gene:ENSPMAG00000004080.1 transcript:ENSPMAT00000004494.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 90.5077 bits (223), Expect = 1.143e-18 Identity = 57/184 (30.98%), Postives = 92/184 (50.00%), Query Frame = 1
Query: 3082 DALFGVPLEVLVSRDLNRQGETDGQECRVPIIVRRCTEEVEKRGLDVVSIYRLSGAVKLKIRIREMLEQDVIAADLSADTVPDIHAITAVLRDFLRELPEPLFTNALYRMILDALQVSLPGDNYAGAKLMLNILDCLPIVNQDTILHLLDHLK-RVSSRSEVNKMTNEALAASLGPVLFFPSPE 3630
+ +FG PL+ L R+ + VP R + VE+ GL V IYR+SG + ++R +++ + DL D+H IT L+ F RELPEPLF + ++A+++ D + M ++ LP N++T+ L +HL RV + + N+M+ + LA GP L P E
Sbjct: 409 EQVFGCPLQTLCEREGSA----------VPNFARLSVQCVERTGLQVDGIYRVSGNLATIQKLRFIVDHEE-KLDLEEPQWDDVHVITGALKMFFRELPEPLFPFKFFPHFINAIKIK---DYAEKIRCMGKLIAILPPTNRETMKLLFNHLATRVVAHGKTNRMSVQNLAIVFGPTLLRPEQE 578
BLAST of Rho GTPase-activating protein vs. Ensembl Sea Lamprey
Match: ARHGAP15 (Rho GTPase activating protein 15 [Source:HGNC Symbol;Acc:HGNC:21030]) HSP 1 Score: 90.8929 bits (224), Expect = 1.277e-18 Identity = 54/180 (30.00%), Postives = 90/180 (50.00%), Query Frame = 1
Query: 3082 DALFGVPLEVLVSRDLNRQGETDGQECRVPIIVRRCTEEVEKRGLDVVSIYRLSGAVKLKIRIREMLEQDVIAADLSADTVPDIHAITAVLRDFLRELPEPLFTNALYRMILDALQVSLPGDNYAGAKLMLNILDCLPIVNQDTILHLLDHLKRVSSRSEVNKMTNEALAASLGPVLFFP 3621
+ +FG PL L R + VP+ VR C +E + L++ +YR+SG ++R M++ D DL DI+ IT L+ F RELPEPL + + A+++ + + K M ++++ LP+ N +T+ L+ HLK V + E N+M+ + +A P L P
Sbjct: 603 EQVFGCPLACLCER----------ENSMVPLFVRMCMIALEWQRLEIDGVYRVSGNQATIQKLRIMVDHDE-HVDLDDSQWEDINVITGALKLFFRELPEPLVPYIFFEQFIAAIKIF---EYHNRVKCMKDLINILPLPNHNTMKFLIRHLKTVVAHGEKNRMSMQNMAIVFAPTLLRP 768
BLAST of Rho GTPase-activating protein vs. Ensembl Sea Lamprey
Match: chn2 (chimerin 2 [Source:ZFIN;Acc:ZDB-GENE-091020-5]) HSP 1 Score: 82.4185 bits (202), Expect = 1.305e-17 Identity = 52/155 (33.55%), Postives = 86/155 (55.48%), Query Frame = 1
Query: 3169 PIIVRRCTEEVEKRGLDVVSIYRLSGAVKLKIRIREMLEQDVIAADLSADTVPDIHAITAVLRDFLRELPEPLFTNALYRMILDALQVSLPGDNYAGAKLMLNILDCLPIVNQDTILHLLDHLKRVSSRSEVNKMTNEALAASLGPVLFFPSPEE 3633
P++V C +E+E RGL +YR+SG + ++ ++D AD+SA++ DI+ IT L+ + R+LP PL T Y ++A ++ + G L + LP + +++ +L+ HLKRV+ S+ N M+ E LA GP L P PE+
Sbjct: 46 PMVVDMCIKEIEMRGLRSEGLYRVSGFSEHIEDVKMAFDRDGEKADISANSYDDINIITGALKLYFRDLPIPLITYDAYPKFIEASKLMDADERLEGIHEALRL---LPPAHYESLRYLMAHLKRVTLYSKENLMSAENLAIVFGPTLMRP-PEQ 196
BLAST of Rho GTPase-activating protein vs. Ensembl Yeast
Match: RGD1 (GTPase-activating protein (RhoGAP) for Rho3p and Rho4p; possibly involved in control of actin cytoskeleton organization [Source:SGD;Acc:S000000464]) HSP 1 Score: 72.4034 bits (176), Expect = 3.569e-13 Identity = 55/186 (29.57%), Postives = 88/186 (47.31%), Query Frame = 1
Query: 3091 FGVPLEVLVSRDLNRQGETDGQECRVPIIVRRCTEEVEKRGLDVVSIYRLSGAVKLKIRIREMLEQDVIAADLSADTVP----DIHAITAVLRDFLRELPEPLFTNALYRMILDALQVSLPGDNYAGAKLMLNILDCLPIVNQDTILHLLDHLKRVSSRSEVNKMTNEALAASLGPVLFFPSPEEA 3636
FGVPLE L+ + ++ VP IVR+C ++K GLD IYR S V +++E +++D + + P DI+ + ++L+ F LP+ + AL I LQ+ P M ++ LP T+ L+ HLKRV + N+M AL GP + +P++A
Sbjct: 470 FGVPLESLI----------EFEQDMVPAIVRQCIYVIDKFGLDQEGIYRKSANVLDVSKLKEEIDKDPANISMILPSKPHSDSDIYLVGSLLKTFFASLPDSVLPKALSSEIKVCLQIEDPT---TRKNFMHGLIYNLPDAQYWTLRALVFHLKRVLAHEAQNRMNLRALCIIWGPTIAPANPDDA 642
BLAST of Rho GTPase-activating protein vs. Ensembl Yeast
Match: BEM2 (Rho GTPase activating protein (RhoGAP); involved in the control of cytoskeleton organization and cellular morphogenesis; required for bud emergence; potential GAP for Rho4p [Source:SGD;Acc:S000000957]) HSP 1 Score: 68.5514 bits (166), Expect = 7.089e-12 Identity = 49/178 (27.53%), Postives = 86/178 (48.31%), Query Frame = 1
Query: 3082 DALFGVPLEVLVSRDLNRQGETDGQECRVPIIVRRCTEEVEKRGLDVVSIYRLSGAVKLKIRIREMLEQDVIAAD---LSADTVPDIHAITAVLRDFLRELPEPLFTNALYRMILDALQVSLPGDNYAGA-----KLMLNILDCLPIVNQDTILHLLDHLKRVSSRSEVNKMTNEALA 3591
+ +FGVPLE + R + +P IV + EE+E RGLD V +YR+ G++ ++ +++ + L D +++AI + +LRELP+ LF++A M+ D +++ +A ++M +L LP T+ ++ HL +V NKM LA
Sbjct: 1962 NKIFGVPLEDVCER----------ENTLIPTIVVKLLEEIELRGLDEVGLYRIPGSIGSINALKNAFDEEGATDNSFTLEDDRWFEVNAIAGCFKMYLRELPDSLFSHA---MVNDFTDLAIKYKAHAMVNEEYKRMMNELLQKLPTCYYQTLKRIVFHLNKVHQHVVNNKMDASNLA 2126
BLAST of Rho GTPase-activating protein vs. Ensembl Yeast
Match: LRG1 (GTPase-activating protein (GAP); contains Rho1p-specific GAP activity, interacting with activated forms of Rho1p; functions along with Sac7p as a negative regulator of the Pkc1p-mediated cell wall integrity signaling pathway; negative regulator of cell wall 1,3-beta-glucan biosynthesis; required for efficient cell fusion; contains a RhoGAP domain and three Lin-11-Isl1-Mec-3 (LIM) domains [Source:SGD;Acc:S000002399]) HSP 1 Score: 61.6178 bits (148), Expect = 8.559e-10 Identity = 50/196 (25.51%), Postives = 94/196 (47.96%), Query Frame = 1
Query: 3064 KMPVNTDALFGVPLEVLVSR-DLNRQGETDGQECRVPIIVRRCTEEVEKRGLDVVSIYRLSGAVKLKIRIREMLEQDVIAADLSADTVPDIHA-----ITAVLRDFLRELPEPLFTNALYRMILDALQVSLPGDNYAGAKLMLNILDCLPIVNQDTILHLLDHLKRVSSRSEV-----NKMTNEALAASLGPVLFF 3618
K P+ T +FG PL+VL + ++ + R+PII+ + + + V I+R +G ++ R+RE+ D + PD ++A+L+ F+RELP+P+ + LY + + A ++ L + +++L I LP N++ + LL L SS S + +KM L+ + P + +
Sbjct: 720 KKPI-TKTVFGAPLDVLCEKWGVDSDLGVGPVKIRIPIIIDELISSLRQMDMSVEGIFRKNGNIR---RLRELTAN----IDSNPTEAPDFSKENAIQLSALLKKFIRELPQPILSTDLYELWIKAAKIDLEDEK---QRVILLIYSLLPTYNRNLLEALLSFLHWTSSFSYIENEMGSKMDIHNLSTVITPNILY 904
BLAST of Rho GTPase-activating protein vs. Ensembl Yeast
Match: RGA2 (GTPase-activating protein for polarity-establishment protein Cdc42p; implicated in control of septin organization, pheromone response, and haploid invasive growth; regulated by Pho85p and Cdc28p; RGA2 has a paralog, RGA1, that arose from the whole genome duplication [Source:SGD;Acc:S000002787]) HSP 1 Score: 58.5362 bits (140), Expect = 8.328e-9 Identity = 43/159 (27.04%), Postives = 75/159 (47.17%), Query Frame = 1
Query: 3211 GLDVVSIYRLSGAVKLKIRIREMLEQ------DVIAADLSADTVPDIHAITAVLRDFLRELPEPLFTNALYRMILDAL-------QVSLPGDNYAGA-----------KLMLNILDCLPIVNQDTILHLLDHLKRVSSRSEVNKMTNEALAASLGPVLF 3615
GL++ +YR SG+ L I Q D ++ L+A DIHA+ +VL+ +LR+LP+P+ + ++Y ++D + ++ L D + + K +L I LP+ +Q+ + L H+ +V SE N M L+ P L
Sbjct: 818 GLNMEGLYRKSGSQTLVEEIENEFAQNNSLHSDTLSPKLNALLNQDIHAVASVLKRYLRKLPDPVLSFSIYDALIDLVRNNQLIERLPLNNDKFLDSPQKVTIYEMVLKSLLEIFKILPVEHQEVLKVLAAHIGKVRRCSERNLMNLHNLSLVFAPSLI 976
BLAST of Rho GTPase-activating protein vs. Ensembl Yeast
Match: RGA1 (GTPase-activating protein for polarity-establishment protein Cdc42p; implicated in control of septin organization, pheromone response, and haploid invasive growth; relocalizes from bud neck to cytoplasm upon DNA replication stress; RGA1 has a paralog, RGA2, that arose from the whole genome duplication [Source:SGD;Acc:S000005653]) HSP 1 Score: 51.9878 bits (123), Expect = 7.909e-7 Identity = 49/177 (27.68%), Postives = 85/177 (48.02%), Query Frame = 1
Query: 3166 VPIIVRRCTE--EVEKRGLDVVSIYRLSGAVKLKIRIREMLEQDVIAADLSADT-VP------DIHAITAVLRDFLRELPEPLFTNALYRMILDALQVSLPGDN--YAGAKLML----------------NILDCLPIVNQDTILHLLDHLKRVSSRSEVNKMTNEALAASLGPVLF 3615
+P+I+ C + E ++ + IYR SG+ +L I E +E+ A + +T P D++ +T VL+ +LR+LP P+FT +Y ++ ++ +N + G KL L NIL+ LP + + L +H+++V+ S N+MT LA P L
Sbjct: 804 IPMILSVCIDFIESDEENMRSEGIYRKSGS-QLVI---EEIEKQFSAWKVQQNTETPNILTEQDLNVVTGVLKRYLRKLPNPIFTFQIYEPLMRLVKSKKMMENLPFVGGKLSLEAKNSDTYMSSKSALKNILEDLPREHYRVLRVLSEHIEKVTRYSHWNRMTLYNLALVFAPGLI 976
BLAST of Rho GTPase-activating protein vs. Ensembl Nematostella
Match: EDO47441 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RM51]) HSP 1 Score: 154.066 bits (388), Expect = 6.611e-38 Identity = 112/346 (32.37%), Postives = 175/346 (50.58%), Query Frame = 1
Query: 2677 SGMLVIHVVAGIGLNSSQTVVRDLYCVLEIDS----VRRARSMIRTSTEIFEWDEI-----------------FELDVEDNDWLAFLFYQWDPRNRHRL-----CFYGNVALRQLIERFRHSYTNSEK--LALYLEPKGVLFIELLYLKINEVFQRFKMPVNTDALFGVPLEVLVSRDLNRQGETDGQECRVPIIVRRCTEEVEKRGLDVVSIYRLSGAVKLKIRIREMLEQDVIAADLSADTVPDIHAITAVLRDFLRELPEPLFTNALYRMILDALQVSLPGDNYAGAKLMLNILDCLPIVNQDTILHLLDHLKRVSSRSEVNKMTNEALAASLGPVLFFPSPE 3630
+G+L +HV G G + S DLYC LE+D V++AR+ I +T WD+ F+L+VE L Y ++R+ L C G + LR R S + +K + + L+ +G + + L Y K + +R K VN+ +FGV +E + SR + C +P+IV C E+EKRGL+ V IYRLSGA R++E +++ +A L + DIHA+ + + +LR+LPEPLFT+ LY + A ++ D + ML + LP N+ T +L HL++V+ +SEV+KM L+ GP + PSP+
Sbjct: 459 NGVLYVHVQNGKGFHRS-----DLYCTLEVDHFGQFVKKARTKIAKTTGDPVWDQGTGGETLDTCPFINMSQDFDLEVEGTKELRIHVYS---KSRYTLQRDEECGLGRIQLR------RESLADLKKRTITIALDKQGAITLSLQYSKTRQGIER-KKSVNSVGVFGVDIETVTSR----------ESCDIPLIVIGCVREIEKRGLEEVGIYRLSGASSDVKRLKEGFDENSQSA-LVLVSEADIHAVAGLFKMYLRDLPEPLFTDELYDKFVKAYAMA---DAEEKRETMLELFQSLPTPNRLTACYLFQHLRKVAEKSEVHKMGLNNLSTVFGPNVLRPSPK 775
BLAST of Rho GTPase-activating protein vs. Ensembl Nematostella
Match: EDO38242 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SDK1]) HSP 1 Score: 112.464 bits (280), Expect = 3.316e-28 Identity = 57/154 (37.01%), Postives = 92/154 (59.74%), Query Frame = 1
Query: 3154 QECRVPIIVRRCTEEVEKRGLDVVSIYRLSGAVKLKIRIREMLEQDVIAADLSADTVPDIHAITAVLRDFLRELPEPLFTNALYRMILDALQVSLPGDNYAGAK-LMLNILDCLPIVNQDTILHLLDHLKRVSSRSEVNKMTNEALAASLGPVL 3612
++ VP++VR+C E+EKRGL+ V +YR+SG + K +R +++ A D+S + PDI+ IT +L+D+LRELPEPL T + + A + + K +M +L LP N+ T++ +L+HL+ V + E NKM L+ L PV+
Sbjct: 37 EQSSVPLLVRKCVLEIEKRGLESVGLYRISGNARRKKELRGFFDENSEAVDISEENCPDINVITGILKDYLRELPEPLITEKMTEGLRKAAKNEIQDKKVDEQKQVMSELLSGLPDPNRHTLVFILNHLRHVMEKKEFNKMDARNLSVCLAPVM 190
BLAST of Rho GTPase-activating protein vs. Ensembl Nematostella
Match: EDO49474 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RG60]) HSP 1 Score: 85.8853 bits (211), Expect = 1.836e-17 Identity = 61/180 (33.89%), Postives = 92/180 (51.11%), Query Frame = 1
Query: 3082 DALFGVPLEVLVSRDLNRQGETDGQECRVPIIVRRCTEEVEKRGLDVVSIYRLSGAVKLKIRIREMLEQDVIAADLSADTVPDIHAITAVLRDFLRELPEPLFTNALYRMILDALQVSLPGDNYAGAKLMLNILDCLPIVNQDTILHLLDHLKRVSSRSEVNKMTNEALAASLGPVLFFP 3621
+ +FG P+ L R+ G T +PI V +C +E RGL+ IYR+ G V L RIR M++Q+ A L D+HA+ L+ + RE+PEPL + ++A++ S K +++ LP +N DT+ LL HL +V SEVN+M + LA GP + P
Sbjct: 199 EQVFGCPITHLCERE----GTT------IPIFVSKCINAIESRGLEFDGIYRVCGNVALVQRIRIMVDQEEPIA-LGESPFDDVHALAGSLKLYFREMPEPLVPFDFFSGFVEAIKQSTRNSKLGALK---SLVGQLPRINFDTLKLLLGHLHKVMGFSEVNRMHAQNLAIVWGPNMMRP 364
BLAST of Rho GTPase-activating protein vs. Ensembl Nematostella
Match: EDO49053 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RHX5]) HSP 1 Score: 83.9593 bits (206), Expect = 2.465e-16 Identity = 53/149 (35.57%), Postives = 81/149 (54.36%), Query Frame = 1
Query: 3166 VPIIVRRCTEEVEKRGLDVVSIYRLSGAVKLKIRIREMLEQDVIAADLSADTVPDIHAITAVLRDFLRELPEPLFTNALYRMILDALQVSLPGDNYAGAKLMLNILDCLPIVNQDTILHLLDHLKRVSSRSEVNKMTNEALAASLGPVL 3612
VP IV +C E+EKRGL+ V +YR+ GA + I+E+ ++ + + DIH + VL+DFLR L EPL T L+ ++A D+++ M + LP N+DT+ L+ HL++VS ++ KM LA GP L
Sbjct: 382 VPAIVVQCISEIEKRGLNEVGLYRVPGAER---SIKELKDKFLHGKTQNLHETIDIHVVCGVLKDFLRNLAEPLVTYHLWGAFVNAANKDDDQDSFSA---MYQAVSELPQANRDTLACLVVHLQKVSQCTDC-KMPVSNLARVFGPTL 523
BLAST of Rho GTPase-activating protein vs. Ensembl Nematostella
Match: EDO47995 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RKJ0]) HSP 1 Score: 79.337 bits (194), Expect = 3.585e-15 Identity = 56/196 (28.57%), Postives = 99/196 (50.51%), Query Frame = 1
Query: 3040 INEVFQRFKMPVNTDAL---FGVPLEVLVSRDLNRQGETDGQECRVPIIVRRCTEEVEKRGLDVVSIYRLSGAVKLKIRIREMLEQDVIAADLSADTVPDIHAITAVLRDFLRELPEPLFTNALYRMILDALQVSLPGDNYAGAKLMLNILDCLPIVNQDTILHLLDHLKRVSSRSEVNKMTNEALAASLGPVLFF 3618
+ +V K V + +L FG PLE L Q + + ++ C + + L ++R++G+ +++ + ++ DL+ + D+HAIT VL+ +LRELPEPL T ALY D +Q + D+ A + ++D LP N+D + +L+ L +++ SEVNKMT +A + P + +
Sbjct: 233 LQDVLPLLKTQVESSSLRSVFGCPLE----EHLKVQRRS------IAFVLEECLTYLHEEALQEQGLFRMAGSSGKIRKLKAAFDAGMV--DLT-EFDCDVHAITGVLKQYLRELPEPLMTFALYD---DWIQAASIQDSGARLQAYWGLVDKLPKANKDNLRYLICFLGKLADYSEVNKMTASNIAIVIAPNIIY 412
BLAST of Rho GTPase-activating protein vs. Ensembl Medaka
Match: SYDE2 (synapse defective Rho GTPase homolog 2 [Source:NCBI gene;Acc:101168857]) HSP 1 Score: 199.134 bits (505), Expect = 7.189e-51 Identity = 139/468 (29.70%), Postives = 227/468 (48.50%), Query Frame = 1
Query: 2371 FDNATRTDLSYFRAPNNVLEYSSPGYAFSSNAQNDFRSTASAPSFRSLRQPSRPKDQQMDHGEQSV--SRLDPNEFRKIQTEQWPPVLASGGHPQRNKSATGYVSGMLVIHVVAGIGLNSSQTVVRDLYCVLEIDSVRRARSMIRTS-TEIFEWDEIFELDVEDNDWLAFLFYQWDPR-NRHRLCFYGNVALRQLIERFRHSYTNSEKLALYLEPKGVLFIEL-LYLKINEVFQRFKMPVNTDALFGVPLEVLVSRDLNRQGETDGQECRVPIIVRRCTEEVEKRGLDVVSIYRLSGAVKLKIRIREMLEQDVIAADLSADTVPDIHAITAVLRDFLRELPEPLFTNALYRMILDALQVSLPGDNYAGAKL-------MLNILDCLPIVNQDTILHLLDHLKRVSSRSEVNKMTNEALAASLGPVLFFPSPEEAXXXXXXXXXXXXQA---------QTLLYILNIWP 3711
D++ T SY + NN S+ + S+ + S + + R K+ + G + + LD + FR + P T Y+SG++ +H L + RD+YC +++DSV +AR+ + T T + D F +++E+ L + + W+P R+R+C +G V L + FR T +LA+ LEP+G+++++L L R +FGV +V R E G VP+I+ +C E+EKRG VV +YRL G+ +K +RE E+D A +L+ PDI+ IT VL+D+LRELP PL LY +L+++ AG ++ +++L+ LP V + T+ LL+HLKRV+S +VNKMT + LA GPVL E + ++ +D ++ A + L Y+L +WP
Sbjct: 928 LDSSVSTQNSYSKKKNNGSSKSASKGGYLSDGDSPELVAKSGKHGTAEGKGGRTKETEGGLGSSRLNGTELDIDAFRHYSFTEQP-------------KCTQYISGLMSLHFYGAEDLKPPRIDSRDVYCAIQVDSVNKARTALLTCRTTFLDMDHTFNIELENAQHLKLVVFSWEPTPKRNRVCCHGTVVLPSI---FR--VTRFHQLAVKLEPRGLIYVKLSLIEHWQNSLDRGPDADREPQVFGVEAWRVVER------ENTG--LMVPLIISKCINEIEKRGCQVVGLYRLCGSAAVKKELREAFERDSHAVELNESVYPDINVITGVLKDYLRELPFPLINKPLYEAVLESMATKPLKMGAAGCEIEQADSEHTVSLLEHLPEVERMTLRTLLNHLKRVASHQDVNKMTCQNLAVCFGPVLLSQRQEASCHTNRVFIDSEELASALHFKKHIEVLHYLLQLWP 1369
BLAST of Rho GTPase-activating protein vs. Ensembl Medaka
Match: SYDE1 (synapse defective Rho GTPase homolog 1 [Source:NCBI gene;Acc:101165963]) HSP 1 Score: 147.132 bits (370), Expect = 3.065e-35 Identity = 106/346 (30.64%), Postives = 180/346 (52.02%), Query Frame = 1
Query: 2674 VSGMLVIHVVAGIGLNSSQTV-VRDLYCVLEIDSVRRARSMIRT-STEIFEWDEIFELDVEDNDWLAFLFYQWDPRN---------------RHRLCFYGNVALRQLIERFRHSYTNSEKLALYLEPKGVLFIELLYLKINEVFQRFKM-----PVNTDALFGVPLEVLVSRDLNRQGETDGQECRVPIIVRRCTEEVEKRGLDVVSIYRLSGAVKLKIRIREMLEQDVIAADLSADTVPDIHAITAVLRDFLRELPEPLFTNALYRMILDALQV-SLPGDNYAG----AKLMLNILDCLPIVNQDTILHLLDHLKRVSSRSEVNKMTNEALAASLGPVLFFPSPE 3630
V+G+L +H++ + +S++ +D++ ++ID RAR+ + T + F L++E L + P N R+R+C G V++ L + R S++L + LEP+G+L+ L L + E + M P N +FG+ L LV E + VP+++++ E+E+RGL VV +YRL G+ +K +R+ E++ A LS D PDI+ +T +L+D+LRELP PL T LY+++ +A+ + + P + ++ + +L CLP + T+ LLDHL V+S S N+MT++ LA GPVL P+ E
Sbjct: 430 VTGLLTVHLLGLEDMKTSRSENSKDIFVAIQIDGATRARTALLTLKGSSLTLNHTFHLELERARQLRIVVLT--PANPAAGGHQPATSGGPTRNRVCCLGGVSIPPLFKGSR-----SQQLCVKLEPRGLLY---LKLSLQEKWDTQPMGDTSTPAN---VFGIELHQLV--------EKEESAVPVPLLIQKTVAEIERRGLKVVGLYRLCGSAAVKKELRDWFERNSSAVRLSEDLYPDINVVTGILKDYLRELPSPLITRTLYQVVREAMAIRTAPSPPESPDPQLSRSTVGLLSCLPTPERATLSLLLDHLSLVASFSSFNRMTHQNLAVCFGPVLLTPTQE 754
BLAST of Rho GTPase-activating protein vs. Ensembl Medaka
Match: ABR (ABR activator of RhoGEF and GTPase [Source:NCBI gene;Acc:101164832]) HSP 1 Score: 135.576 bits (340), Expect = 1.460e-31 Identity = 113/378 (29.89%), Postives = 170/378 (44.97%), Query Frame = 1
Query: 2680 GMLVIHVVAGIGLNSSQTVVRDLYCVLEIDS----VRRARSMIRTSTEIFEWDEIFELDVEDNDWLAFLFYQWDPRNRHRLCFYGNVALRQLIERFRHSYTNS--EKLALYLEPKGVLF--IELLYLKINEVFQRFKMPVNT-------------DALFGVPLEVLVSRDLNRQGETDGQECRVPIIVRRCTEEVEKRGLDVVSIYRLSGAVKLKIRIREMLEQDVIAADLSADTVP----------DIHAITAVLRDFLRELPEPLFTNALYRMILDALQVSLPGDNYAGAKLMLNILDCLPIVNQDTILHLLDHLKRVSSRSEVNKMTNEALAASLGPVLFFPSPEEAXXXXXXXXXX-------XXQAQTLLYIL 3699
G L + V + G S +LYC LE+DS V +A++ + T W+E FE+++E + +L L Y+ N + ++ + + + K + L+P+ V ++ +++N + F M + +FGV + V+ R + +VP IVR+C EEVEKRG+D V IYR+SG D+ A L+ DT DI+AI L+ + RELPEPL T+ LY ++ + +S P A M+++L LP N T L LLDHLKRV+ + VNKM+ LA GP L PS E+ K + Q Q LLY L
Sbjct: 739 GFLHVIVHSAKGFKESA----NLYCTLEVDSFGYFVSKAKTRVFRDTAEPSWNEEFEIELEGSQYLRILCYE-------------NCYDKSMLNKDDNEIVDKIMGKGQVQLDPQTVQSKNWQMDVIEMNGIKVEFSMKFTSRDLSLKRTPSKKQSGVFGVKISVVTKR----------ERSKVPYIVRQCIEEVEKRGIDEVGIYRISGVA-----------TDIQALKLAFDTNTKDILMMLSDMDINAIAGTLKLYFRELPEPLLTDRLYPAFMEGIALSDPA---AKENCMMHLLRSLPEPNIMTFLTLLDHLKRVAEKEPVNKMSLHNLATVFGPTLLRPSESESLKGQHIMSATDIWSHDVMGQVQVLLYYL 1075
BLAST of Rho GTPase-activating protein vs. Ensembl Medaka
Match: ABR (ABR activator of RhoGEF and GTPase [Source:NCBI gene;Acc:101164832]) HSP 1 Score: 132.88 bits (333), Expect = 5.872e-31 Identity = 113/377 (29.97%), Postives = 173/377 (45.89%), Query Frame = 1
Query: 2680 GMLVIHVVAGIGLNSSQTVVRDLYCVLEIDS----VRRARSMIRTSTEIFEWDEIFELDVEDNDWLAFLFYQWDPRNRHRLCFYGNVALRQLIERFRHSYTNSEKLALYLEPKGVLF--IELLYLKINEVFQRFKMPVNT-------------DALFGVPLEVLVSRDLNRQGETDGQECRVPIIVRRCTEEVEKRGLDVVSIYRLSGAVKLKIRIREMLEQDVIAADLSADTVP----------DIHAITAVLRDFLRELPEPLFTNALYRMILDALQVSLPGDNYAGAKLMLNILDCLPIVNQDTILHLLDHLKRVSSRSEVNKMTNEALAASLGPVLFFPSPEEAXXXXXXXXXX-------XXQAQTLLYILN 3702
G L + V + G S +LYC LE+DS V +A++ + T W+E FE+++E + +L L Y+ + ++ L N + +++ + + + L+P+ V ++ +++N + F M + +FGV + V+ R + +VP IVR+C EEVEKRG+D V IYR+SG D+ A L+ DT DI+AI L+ + RELPEPL T+ LY ++ + +S P A M+++L LP N T L LLDHLKRV+ + VNKM+ LA GP L PS E+ K + Q Q LLY L
Sbjct: 495 GFLHVIVHSAKGFKESA----NLYCTLEVDSFGYFVSKAKTRVFRDTAEPSWNEEFEIELEGSQYLRILCYE-NCYDKSMLNKDDNEIVDKIMGKGQ----------VQLDPQTVQSKNWQMDVIEMNGIKVEFSMKFTSRDLSLKRTPSKKQSGVFGVKISVVTKR----------ERSKVPYIVRQCIEEVEKRGIDEVGIYRISGVAT-----------DIQALKLAFDTNTKDILMMLSDMDINAIAGTLKLYFRELPEPLLTDRLYPAFMEGIALSDPA---AKENCMMHLLRSLPEPNIMTFLTLLDHLKRVAEKEPVNKMSLHNLATVFGPTLLRPSESESLKGQHIMSATDIWSHDVMGQVQVLLYYLQ 832
BLAST of Rho GTPase-activating protein vs. Ensembl Medaka
Match: ABR (ABR activator of RhoGEF and GTPase [Source:NCBI gene;Acc:101164832]) HSP 1 Score: 132.88 bits (333), Expect = 7.209e-31 Identity = 113/377 (29.97%), Postives = 173/377 (45.89%), Query Frame = 1
Query: 2680 GMLVIHVVAGIGLNSSQTVVRDLYCVLEIDS----VRRARSMIRTSTEIFEWDEIFELDVEDNDWLAFLFYQWDPRNRHRLCFYGNVALRQLIERFRHSYTNSEKLALYLEPKGVLF--IELLYLKINEVFQRFKMPVNT-------------DALFGVPLEVLVSRDLNRQGETDGQECRVPIIVRRCTEEVEKRGLDVVSIYRLSGAVKLKIRIREMLEQDVIAADLSADTVP----------DIHAITAVLRDFLRELPEPLFTNALYRMILDALQVSLPGDNYAGAKLMLNILDCLPIVNQDTILHLLDHLKRVSSRSEVNKMTNEALAASLGPVLFFPSPEEAXXXXXXXXXX-------XXQAQTLLYILN 3702
G L + V + G S +LYC LE+DS V +A++ + T W+E FE+++E + +L L Y+ + ++ L N + +++ + + + L+P+ V ++ +++N + F M + +FGV + V+ R + +VP IVR+C EEVEKRG+D V IYR+SG D+ A L+ DT DI+AI L+ + RELPEPL T+ LY ++ + +S P A M+++L LP N T L LLDHLKRV+ + VNKM+ LA GP L PS E+ K + Q Q LLY L
Sbjct: 501 GFLHVIVHSAKGFKESA----NLYCTLEVDSFGYFVSKAKTRVFRDTAEPSWNEEFEIELEGSQYLRILCYE-NCYDKSMLNKDDNEIVDKIMGKGQ----------VQLDPQTVQSKNWQMDVIEMNGIKVEFSMKFTSRDLSLKRTPSKKQSGVFGVKISVVTKR----------ERSKVPYIVRQCIEEVEKRGIDEVGIYRISGVAT-----------DIQALKLAFDTNTKDILMMLSDMDINAIAGTLKLYFRELPEPLLTDRLYPAFMEGIALSDPA---AKENCMMHLLRSLPEPNIMTFLTLLDHLKRVAEKEPVNKMSLHNLATVFGPTLLRPSESESLKGQHIMSATDIWSHDVMGQVQVLLYYLQ 838
BLAST of Rho GTPase-activating protein vs. Planmine SMEST
Match: SMESG000017186.1 (SMESG000017186.1) HSP 1 Score: 2588.91 bits (6709), Expect = 0.000e+0 Identity = 1301/1305 (99.69%), Postives = 1302/1305 (99.77%), Query Frame = 1
Query: 235 MDYNSSSIEQKEIIPMTPVVNIKPPSYKIIRIEFPNSEKNLLTILNENDSMNSMVTIYTSQTTVLSDILFENCLFFVTQVSKMPGQSLGIFLRDGDPFTDEPGLFVSRLSDNLSISLQSVNQERELMKVEIKSPDIIPDNNAFVVESQLAHQQNPSENDSSNNTSHSAYDCNIHNNSTSNPCYRSNFSLKKNCSASFSNENSPSDLIGGFCDEISKLQTNIFPFQIGDRICRVRISDSTHSHQDNNDCSIIEKIDNYSRSDGTNNNKRNDAEKKYNLDDVVLFMSISSFLELSILREGRNNQKPSLEQVDEKSSTYDEESN-KFFVDEQIRRVSFQLSDQESQSLSPGPSIDCEQEEIVSKTLSLNSEKTKDQRVRFDEFESSPIWDHLHPSMANSVPTMLNSTISLDRTNFSEKHKSTSKNILLREVPTEDSNDSGLSSENSWLPSIISTTNHSLPLDTTNTVTICNMSAPDSFGTGNPMRTVHFAGSKIHSQTVPTEVYNPSHQVPWPYQRASLTNPRTVTFRTNQKASIXXXXXXXXXXXLKNVYWPQNFYIPRHTGPLYPSQSLSDPRMLNYRWISPPVAQSYPVEVADKGIQCGPDRHGYNSDTELKMKSHQPFPVDMHSLNKSQVKFSVSRTAPHLHRSTVNYSSGEEEGFYQATSPSRYIDPKQSMMCSNQNMMYKQVSSQPSIEDEMRNLNIRPYMPVPMMETDFFDNATRTDLSYFRAPNNVLEYSSPGYAFSSNAQNDFRSTASAPSFRSLRQPSRPKDQQMDHGEQSVSRLDPNEFRKIQTEQWPPVLASGGHPQRNKSATGYVSGMLVIHVVAGIGLNSSQTVVRDLYCVLEIDSVRRARSMIRTSTEIFEWDEIFELDVEDNDWLAFLFYQWDPRNRHRLCFYGNVALRQLIERFRHSYTNSEKLALYLEPKGVLFIELLYLKINEVFQRFKMPVNTDALFGVPLEVLVSRDLNRQGETDGQECRVPIIVRRCTEEVEKRGLDVVSIYRLSGAVKLKIRIREMLEQDVIAADLSADTVPDIHAITAVLRDFLRELPEPLFTNALYRMILDALQVSLPGDNYAGAKLMLNILDCLPIVNQDTILHLLDHLKRVSSRSEVNKMTNEALAASLGPVLFFPSPEEAXXXXXXXXXXXXQAQTLLYILNIWPDESDHQYHSRDSKSKEPQKIHSNSISNAQKITHITPSTRYSKPSPSTVRTSPNQTDTAATPRKSDAPINSGMNSAENVRSQNNVKNRRPILSNSRRSNSLEMTERDQSRGRSATMXXXXXXXXXXXXXXXXXKVVLVDESSMPYL 4146
MDYNSSSIEQKEIIPMTPVVNIKPPSYKIIRIEFPNSEKNLLTILNENDSMNSMVTIYTSQTTVLSDILFENCLFFVTQVSKMPGQSLGIFLRDGDPFTDEPGLFVSRLSDNLSISLQSVNQERELMKVEIKSPDIIPDNNAFVVESQLAHQQNPSENDSSNNTSHSAYDCNIHNNSTSNPCYRSNFSLKKNCSASFSNENSPSDLIGGFCDEISKLQTNIFPFQIGDRICRVRISDSTHSHQDNNDCSIIEKIDNYSRSDGTNNNKRNDAEKKYNLDDVVLFMSISSFLELSILREGRNNQKPSLEQVDEKSSTYDEESN KFFVDEQIRRVSFQLSDQESQSLSPGPSIDCEQEEIVSKTLSLNSEKTKDQRVRFDEFESSPIWDHLHPSMANSVPTMLNSTISLDRTNFSEKHKSTSKNILLREVPTEDSNDSGLSSENSWLPSIISTTNHSLPLDTTNTVTICNMSAPDSFGTGNPMRTVHFAGSKIHSQTVPTEVYNPSHQVPWPYQRASLTNPRTVTFRTNQKASISSPPSPQSQGPLKNVYWPQNFYIPRHTGPLYPSQSLSDPRMLNYRWISPPVAQSYPVEVADKGIQCGPDRHGYNSDTELKMKSHQPFPVDMHSLNKSQVKFSVSRTAPHLHRSTVNYSSGEEEGFYQATSPSRYIDPKQSMMCSNQNMMYKQVSSQPSIEDEMRNLNIRPYMPVPMMETDFFDNATRTDLSYFRAPNNVLEYSSPGYAF SNAQNDFRSTASAPSFRSLRQPSRPKDQQMDHG+QSVSRLDPNEFRKIQTEQWPPVLASGGHPQRNKSATGYVSGMLVIHVVAGIGLNSSQTVVRDLYCVLEIDSVRRARSMIRTSTEIFEWDEIFELDVEDNDWLAFLFYQWDPRNRHRLCFYGNVALRQLIERFRHSYTNSEKLALYLEPKGVLFIELLYLKINEVFQRFKMPVNTDALFGVPLEVLVSRDLNRQGETDGQECRVPIIVRRCTEEVEKRGLDVVSIYRLSGAVKLKIRIREMLEQDVIAADLSADTVPDIHAITAVLRDFLRELPEPLFTNALYRMILDALQVSLPGDNYAGAKLMLNILDCLPIVNQDTILHLLDHLKRVSSRSEVNKMTNEALAASLGPVLFFPSPEEAKKLDKSLLDPKKQAQTLLYILNIWPDESDHQYHSRDSKSKEPQKIHSNSISNAQKITHITPSTRYSKPSPSTVRTSPNQTDTAATPRKSDAPINSGMNS ENVRSQNNVKNRRPILSNSRRSNSLEMTERDQSRGRSATMSSGNHSRLTSRSSSRDRKVVLVDESSMPYL
Sbjct: 1 MDYNSSSIEQKEIIPMTPVVNIKPPSYKIIRIEFPNSEKNLLTILNENDSMNSMVTIYTSQTTVLSDILFENCLFFVTQVSKMPGQSLGIFLRDGDPFTDEPGLFVSRLSDNLSISLQSVNQERELMKVEIKSPDIIPDNNAFVVESQLAHQQNPSENDSSNNTSHSAYDCNIHNNSTSNPCYRSNFSLKKNCSASFSNENSPSDLIGGFCDEISKLQTNIFPFQIGDRICRVRISDSTHSHQDNNDCSIIEKIDNYSRSDGTNNNKRNDAEKKYNLDDVVLFMSISSFLELSILREGRNNQKPSLEQVDEKSSTYDEESNNKFFVDEQIRRVSFQLSDQESQSLSPGPSIDCEQEEIVSKTLSLNSEKTKDQRVRFDEFESSPIWDHLHPSMANSVPTMLNSTISLDRTNFSEKHKSTSKNILLREVPTEDSNDSGLSSENSWLPSIISTTNHSLPLDTTNTVTICNMSAPDSFGTGNPMRTVHFAGSKIHSQTVPTEVYNPSHQVPWPYQRASLTNPRTVTFRTNQKASISSPPSPQSQGPLKNVYWPQNFYIPRHTGPLYPSQSLSDPRMLNYRWISPPVAQSYPVEVADKGIQCGPDRHGYNSDTELKMKSHQPFPVDMHSLNKSQVKFSVSRTAPHLHRSTVNYSSGEEEGFYQATSPSRYIDPKQSMMCSNQNMMYKQVSSQPSIEDEMRNLNIRPYMPVPMMETDFFDNATRTDLSYFRAPNNVLEYSSPGYAFPSNAQNDFRSTASAPSFRSLRQPSRPKDQQMDHGQQSVSRLDPNEFRKIQTEQWPPVLASGGHPQRNKSATGYVSGMLVIHVVAGIGLNSSQTVVRDLYCVLEIDSVRRARSMIRTSTEIFEWDEIFELDVEDNDWLAFLFYQWDPRNRHRLCFYGNVALRQLIERFRHSYTNSEKLALYLEPKGVLFIELLYLKINEVFQRFKMPVNTDALFGVPLEVLVSRDLNRQGETDGQECRVPIIVRRCTEEVEKRGLDVVSIYRLSGAVKLKIRIREMLEQDVIAADLSADTVPDIHAITAVLRDFLRELPEPLFTNALYRMILDALQVSLPGDNYAGAKLMLNILDCLPIVNQDTILHLLDHLKRVSSRSEVNKMTNEALAASLGPVLFFPSPEEAKKLDKSLLDPKKQAQTLLYILNIWPDESDHQYHSRDSKSKEPQKIHSNSISNAQKITHITPSTRYSKPSPSTVRTSPNQTDTAATPRKSDAPINSGMNSVENVRSQNNVKNRRPILSNSRRSNSLEMTERDQSRGRSATMSSGNHSRLTSRSSSRDRKVVLVDESSMPYL 1305
BLAST of Rho GTPase-activating protein vs. Planmine SMEST
Match: SMESG000037897.1 (SMESG000037897.1) HSP 1 Score: 383.645 bits (984), Expect = 8.815e-116 Identity = 257/702 (36.61%), Postives = 379/702 (53.99%), Query Frame = 1
Query: 1894 IPRHTGPLYPSQSLSDPRMLNYRWISPPVAQSYPVEVADKGIQCGPDRHGYNSDTELKMKSHQPFPVDMHSLNKSQVKFSVSRTAPHLHRSTVNYSSGEEEGFYQATSPSRYIDPKQSMMCSNQNMMYKQVSSQPSIEDEMRNLNIRPYMPVPMMETDFFD--------------NATRTDLSYFRAPNNVLEYSSPGYAFSSNAQNDFRSTASAPSFRSLRQPSRPKDQQMDHGEQSVSRLDPNEFRKIQTEQWPPVLASGGHPQRNK-----SATGYVSGMLVIHVVAGIGLNSSQTVVRDLYCVLEIDSVRRARSMIRTSTEIFEWDEIFELDVEDNDWLAFLFYQWDPRNRHRLCFYGNVALRQLIERFRHSYTNSEKLALYLEPKGVLFIELLYLKINEVFQR-FKMPVNTDALFGVPLEVLVSRDLNRQGETDGQECRVPIIVRRCTEEVEKRGLDVVSIYRLSGAVKLKIRIREMLEQDVIAADLSADTVPDIHAITAVLRDFLRELPEPLFTNALYRMILDALQVSLPGDNYAGAKLMLNILDCLPIVNQDTILHLLDHLKRVSSRSEVNKMTNEALAASLGPVLFFPSPEEAXXXXXXXXXXXXQAQTLLYILNIWPDESDHQYHSRDSKSKEPQKIHSNSISNAQKITHITPSTRYSKPSPSTVRTSPNQTDTAATPRKSDAPINSGMNSAE 3939
I R YPS ++D N R P++ S + G NSDTEL + + + S K SV+R RS +YSSGEE+ F + P Y D + + N + Q S+ +I + + Y P + + +F + TR + R N+ L SS F+ + +F+ S S+ KD ++ Q S++D NEFR I TE +L N +G+ SGMLVIH++AG+GLNSS +V++DLYCV+E D++R+ARSMIRTSTE FEWDE+FE+++ +N L+ L YQWDPR RHRLC++GN+ L LI +R TN+EKLAL LEPKG+L++E+ +L E F R +N ++FG L+ L+ + +P IV+ C +E+ RG +VV IYRLSG++KLKI++++M +++ ++S+D VPDIHAIT+VL+DFLRELPEPLFT A Y+MI++A ++ N +G KLMLNILDCLPI NQ+ +L L+DHL ++ ++SE NKM +L+ GP+LF+PS E + KL KS+LDP Q++ +I+ IWP +S + K TH + S + K ++ N+ + A +P S + M + E
Sbjct: 44 IERSYSNRYPSSGMTDH---NSRLNLAPISHSMRDQSQKIVNYKSRSMSGCNSDTELANGATNNATILD---SDSSSKLSVNRWRVGCRRSLSSYSSGEEDNFSSSNFPVHY-DNTKDVFFEYANS-HNQKGSRQNISETVY------YEPSQLSDHSYFSAIKASYNNVNAQIPSKTRPEKKSHRLDNSNLNSSS---VFT---RENFKKLGVKASTFSI------KDWEI---AQFTSKIDVNEFRHITTEHTDGLLGLLSRRSNNSYIPITRGSGF-SGMLVIHLIAGVGLNSSHSVIKDLYCVIETDALRKARSMIRTSTECFEWDEVFEIEILNNTCLSILLYQWDPRFRHRLCYFGNLTLDSLINHWRMYNTNNEKLALQLEPKGMLYLEIQFLNCEETFHRSGNKTINPRSIFGRSLKDLII--------LEKSPILIPNIVKICVDEINFRGREVVGIYRLSGSIKLKIQLKDMFDREGYHINISSDAVPDIHAITSVLKDFLRELPEPLFTEAFYQMIVNAHELH-KTSNTSGEKLMLNILDCLPIGNQNVLLFLIDHLLKIIAKSESNKMDLVSLSNIFGPLLFYPSLEGSSKLSKSILDPSLQSEIFQFIMTIWPSNI--------------------GLSRSSKYTHESLSRKSQKEMAASTYKHRNRENIANSPENSRNAVPGEMTAGE 686
BLAST of Rho GTPase-activating protein vs. Planmine SMEST
Match: SMESG000039887.1 (SMESG000039887.1) HSP 1 Score: 321.242 bits (822), Expect = 3.102e-92 Identity = 162/403 (40.20%), Postives = 251/403 (62.28%), Query Frame = 1
Query: 2512 LRQPSRPKDQQMDHGEQSVSRLDPNE---FRKIQTEQWPPVLASGGHPQRNKSATGYVSGMLVIHVVAGIGLNSSQTVVRDLYCVLEIDSVRRARSMIRTSTEIFEWDEIFELDVEDNDWLAFLFYQWDPRNRHRLCFYGNVALRQLIERFRHSYTNSEKLALYLEPKGVLFIELLYLKINEVFQRFKMPVNTDALFGVPLEVLVSRDLNRQGETDGQECRVPIIVRRCTEEVEKRGLDVVSIYRLSGAVKLKIRIREMLEQDVIAADLSADTVPDIHAITAVLRDFLRELPEPLFTNALYRMILDALQVSLPGDNYAGAKLMLNILDCLPIVNQDTILHLLDHLKRVSSRSEVNKMTNEALAASLGPVLFFPSPEEAXXXXXXXXXXXXQAQTLLYILNIWP 3711
+ +P P + G + R PNE FR +Q+E+W + S P ++G+LV++V+AG L SS ++ RDLYCVLEIDS+R+ARSMIRTSTE+FEWDEIFE+D+ ++ +L+ L YQWDP+ HRLCFYG + L I+ F+ + ++K+ L LEPKG+L++E+ +L F R + +++FG P+ + S + +C+ P ++ C EE+E+RGLD V +YRL GA KLK +R++LE D+S+ +PDIH IT+VL+DFLRELPEPL T ALYR ++ + S DN G +M+ I + LP VN++++++ +DHL R++ ++++NKMT L+ + +L PS E+ + +++ + L Y+L WP
Sbjct: 534 ISEPKFPAPPIQNTGSLLMERYIPNESKDFRLLQSERWMKPIRSSDQPPG-------IAGILVVNVIAGCSLQSSHSLFRDLYCVLEIDSIRKARSMIRTSTEVFEWDEIFEIDLWNSHFLSILLYQWDPKTHHRLCFYGGINLLTFIDYFQQNVAGADKVILQLEPKGLLYLEMAFLNWELSFIR-QTNNRDNSVFGRPISQIRS----VVSSNNAFDCK-PFVITLCVEEIERRGLDNVGLYRLCGAAKLKAHLRQLLETYHDFTDMSSSVIPDIHVITSVLKDFLRELPEPLLTTALYRNLVKSSFHSDIYDNPEGPMIMITIFNSLPQVNRESLIYFIDHLIRLAQKNDINKMTISELSTNFASLLLQPSCEQLNNYQNLIGLARQEIEFLQYLLTQWP 923
BLAST of Rho GTPase-activating protein vs. Planmine SMEST
Match: SMESG000025211.1 (SMESG000025211.1) HSP 1 Score: 100.523 bits (249), Expect = 5.668e-21 Identity = 91/327 (27.83%), Postives = 153/327 (46.79%), Query Frame = 1
Query: 2674 VSGMLVIHVVAGIGLNSSQTVVRDLYCVLEIDSVR----RARSMIRTSTEIFEWDEIFELDVEDNDWLAFLFYQWD--PRNRHRLCFYGNVALRQLIERFRH-----SYTNSEKLALYLEPKGVLFIELLYLKINEVFQRFKMPVNTDALFGVPLEVLVSRDLNRQGETDGQECRVPIIVRRCTEEVEKRGLDVVSIYRLSGAVKLKIRIREMLEQDVIAADLSADTVPDIHAITAVLRDFLRELPEPLFTNALYRMILDALQVSLPGDNYAGAKLMLNILDCLPIVNQDTILHLLDHLKRVSSRSEVNKMTNEALAASLGPVLFFP 3621
VSG+LV ++ GLN Y +E+DS +AR+ + T + +W+E F++D++ + + L Y+ N+ L Y L +H S ++E L LE L Y NE+ +R + T LFG L+ +V+R+ ++G + VP+I+ C + +E GLD IYR+SG+ + + L ++ A +S D+H IT +++ +LRELPEPL Y IL ++ + ++ ++ LP N T++ +L H ++V + S N+M L LGP L P
Sbjct: 606 VSGVLVTNIFKVDGLNPDFRY----YLSIEVDSFNLNELKARTKVCTGSSSLQWNESFDIDLDCSQMMNILVYEIKNYGENKESLIGYFEFQLNPKDHLNQHITKTVSMLSNESAKLTLEAS------LKYEAKNELLKRQPSIMKT-GLFGFSLKSVVTRE--KKGNVLVE--NVPMIIVACFKRIEDSGLDEEGIYRISGSKNEINELYKKLNKNPSYA-ISNLYTYDLHTITGIVKMYLRELPEPLLMTNNYERILQIAKLEEEVERFSRYN---EVILSLPEPNHSTVIFVLKHFQKVMAHSTKNQMIAGNLGLILGPTLIMP 913
BLAST of Rho GTPase-activating protein vs. Planmine SMEST
Match: SMESG000025211.1 (SMESG000025211.1) HSP 1 Score: 100.523 bits (249), Expect = 5.938e-21 Identity = 91/327 (27.83%), Postives = 153/327 (46.79%), Query Frame = 1
Query: 2674 VSGMLVIHVVAGIGLNSSQTVVRDLYCVLEIDSVR----RARSMIRTSTEIFEWDEIFELDVEDNDWLAFLFYQWD--PRNRHRLCFYGNVALRQLIERFRH-----SYTNSEKLALYLEPKGVLFIELLYLKINEVFQRFKMPVNTDALFGVPLEVLVSRDLNRQGETDGQECRVPIIVRRCTEEVEKRGLDVVSIYRLSGAVKLKIRIREMLEQDVIAADLSADTVPDIHAITAVLRDFLRELPEPLFTNALYRMILDALQVSLPGDNYAGAKLMLNILDCLPIVNQDTILHLLDHLKRVSSRSEVNKMTNEALAASLGPVLFFP 3621
VSG+LV ++ GLN Y +E+DS +AR+ + T + +W+E F++D++ + + L Y+ N+ L Y L +H S ++E L LE L Y NE+ +R + T LFG L+ +V+R+ ++G + VP+I+ C + +E GLD IYR+SG+ + + L ++ A +S D+H IT +++ +LRELPEPL Y IL ++ + ++ ++ LP N T++ +L H ++V + S N+M L LGP L P
Sbjct: 591 VSGVLVTNIFKVDGLNPDFRY----YLSIEVDSFNLNELKARTKVCTGSSSLQWNESFDIDLDCSQMMNILVYEIKNYGENKESLIGYFEFQLNPKDHLNQHITKTVSMLSNESAKLTLEAS------LKYEAKNELLKRQPSIMKT-GLFGFSLKSVVTRE--KKGNVLVE--NVPMIIVACFKRIEDSGLDEEGIYRISGSKNEINELYKKLNKNPSYA-ISNLYTYDLHTITGIVKMYLRELPEPLLMTNNYERILQIAKLEEEVERFSRYN---EVILSLPEPNHSTVIFVLKHFQKVMAHSTKNQMIAGNLGLILGPTLIMP 898 The following BLAST results are available for this feature:
BLAST of Rho GTPase-activating protein vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99) Total hits: 5
BLAST of Rho GTPase-activating protein vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99) Total hits: 5
BLAST of Rho GTPase-activating protein vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99) Total hits: 5
BLAST of Rho GTPase-activating protein vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99) Total hits: 5
BLAST of Rho GTPase-activating protein vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99) Total hits: 5
BLAST of Rho GTPase-activating protein vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99) Total hits: 5
BLAST of Rho GTPase-activating protein vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt) Total hits: 5
BLAST of Rho GTPase-activating protein vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL) Total hits: 5
BLAST of Rho GTPase-activating protein vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99) Total hits: 5
BLAST of Rho GTPase-activating protein vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99) Total hits: 5
BLAST of Rho GTPase-activating protein vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46) Total hits: 5
BLAST of Rho GTPase-activating protein vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46) Total hits: 5
BLAST of Rho GTPase-activating protein vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99) Total hits: 5
BLAST of Rho GTPase-activating protein vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST) Total hits: 5
Analyses
This transcript is derived from or has results from the following analyses Sequences
The following sequences are available for this feature:
transcript sequence >SMED30013182 ID=SMED30013182|Name=Rho GTPase-activating protein|organism=Schmidtea mediterranea sexual|type=transcript|length=4423bpback to top protein sequence of SMED30013182-orf-1 >SMED30013182-orf-1 ID=SMED30013182-orf-1|Name=SMED30013182-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=1305bp MDYNSSSIEQKEIIPMTPVVNIKPPSYKIIRIEFPNSEKNLLTILNENDSback to top Annotated Terms
The following terms have been associated with this transcript:
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
|
