Importin subunit alpha

Overview
NameImportin subunit alpha
Smed IDSMED30013177
Length (bp)2476
Neoblast Clusters

Zeng et. al., 2018




▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 



 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)




Explore this single cell expression dataset with our NB Cluster Shiny App




 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of Importin subunit alpha (SMED30013177) t-SNE clustered cells

Violin plots show distribution of expression levels for Importin subunit alpha (SMED30013177) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of Importin subunit alpha (SMED30013177) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for Importin subunit alpha (SMED30013177) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017




Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020




SMED30013177

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 2

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
gutSMED30013177h1SMcG0013531 dd_Smed_v4_590_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
neoblastSMED30013177h1SMcG0013531 dd_Smed_v4_590_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
BLAST of Importin subunit alpha vs. Ensembl Human
Match: KPNA3 (karyopherin subunit alpha 3 [Source:HGNC Symbol;Acc:HGNC:6396])

HSP 1 Score: 669.078 bits (1725), Expect = 0.000e+0
Identity = 334/487 (68.58%), Postives = 394/487 (80.90%), Query Frame = 3
Query:   69 SIMSDRRNMHKNASKDTDEMRRRRVEGNVELRKNKREETLQKRRNLP---SLEADENEIEEPLQMGNLSEIVANSTNPNPTVRLEAIQAARKLLSSDKNPPIDNLIQSGIMPILVECLDNDAHPNIQFEAAWALTNIASGTSEQTNAVVQAGAVPLFLKLLGSTHSNVCEQAVWALGNIIGDGPTLRDYAISLGVVAPLLKFLNADVPITFLRNVTWVIVNLCRNKDPPPSPVTISELLPALRFLIQNIDTNILVDTVWALSYLTDGGNDQIQMVIEADIVRFLVPLLSHNDVKVQTAALRAVGNIVTGTDEQTQYVLNFDALSHFPQLLQHSKEKINKEAVWFLSNITAGNQEQVQAVIDYSLIPLIIYHLDKGDFQTQKEAAWVISNLTISGTPQQVAFVVQQGVIPPFCKMLSVRDAQVVQVVLDGILNILKVANDQSDLVCTMIEECGGLDLIEQLQHHENGEIYKLAYDIIDNFFN-DEMEE 1517
            S+ + R    KN  +D + MRR R E  VELRKNKR+E L K+RN+P   SLE  + + +   Q   L  I+ N+T+ NP V+L A+QAARKLLSSD+NPPID+LI+SGI+PILV+CL+ D +P++QFEAAWALTNIASGTS QT AVVQ+ AVPLFL+LL S H NVCEQAVWALGNIIGDGP  RDY ISLGVV PLL F++  +PITFLRNVTWVIVNLCRNKDPPP   T+ E+LPAL  LI + D NILVDTVWALSYLTDGGN+QIQMVI++ +V FLVPLLSH +VKVQTAALRAVGNIVTGTDEQTQ VLN D LSHFP LL H KEKINKEAVWFLSNITAGNQ+QVQAVID  LIP+II+ L KGDF TQKEAAW ISNLTISG   QV ++VQQ VIPPFC +LSV+D+QVVQVVLDG+ NIL +A D++  +  +IEECGGL+ IE LQ HEN +IYKLA++IID +F+ D+++E
Sbjct:    6 SLENHRIKSFKNKGRDVETMRRHRNEVTVELRKNKRDEHLLKKRNVPQEESLEDSDVDADFKAQNVTLEAILQNATSDNPVVQLSAVQAARKLLSSDRNPPIDDLIKSGILPILVKCLERDDNPSLQFEAAWALTNIASGTSAQTQAVVQSNAVPLFLRLLRSPHQNVCEQAVWALGNIIGDGPQCRDYVISLGVVKPLLSFISPSIPITFLRNVTWVIVNLCRNKDPPPPMETVQEILPALCVLIYHTDINILVDTVWALSYLTDGGNEQIQMVIDSGVVPFLVPLLSHQEVKVQTAALRAVGNIVTGTDEQTQVVLNCDVLSHFPNLLSHPKEKINKEAVWFLSNITAGNQQQVQAVIDAGLIPMIIHQLAKGDFGTQKEAAWAISNLTISGRKDQVEYLVQQNVIPPFCNLLSVKDSQVVQVVLDGLKNILIMAGDEASTIAEIIEECGGLEKIEVLQQHENEDIYKLAFEIIDQYFSGDDIDE 492          
BLAST of Importin subunit alpha vs. Ensembl Human
Match: KPNA4 (karyopherin subunit alpha 4 [Source:HGNC Symbol;Acc:HGNC:6397])

HSP 1 Score: 669.078 bits (1725), Expect = 0.000e+0
Identity = 334/482 (69.29%), Postives = 400/482 (82.99%), Query Frame = 3
Query:   84 RRNMHKNASKDTDEMRRRRVEGNVELRKNKREETLQKRRNLPSLE-ADENEIEEPLQMGN--LSEIVANSTNPNPTVRLEAIQAARKLLSSDKNPPIDNLIQSGIMPILVECLDNDAHPNIQFEAAWALTNIASGTSEQTNAVVQAGAVPLFLKLLGSTHSNVCEQAVWALGNIIGDGPTLRDYAISLGVVAPLLKFLNADVPITFLRNVTWVIVNLCRNKDPPPSPVTISELLPALRFLIQNIDTNILVDTVWALSYLTDGGNDQIQMVIEADIVRFLVPLLSHNDVKVQTAALRAVGNIVTGTDEQTQYVLNFDALSHFPQLLQHSKEKINKEAVWFLSNITAGNQEQVQAVIDYSLIPLIIYHLDKGDFQTQKEAAWVISNLTISGTPQQVAFVVQQGVIPPFCKMLSVRDAQVVQVVLDGILNILKVANDQSDLVCTMIEECGGLDLIEQLQHHENGEIYKLAYDIIDNFF-NDEMEE 1517
            R    KN  +D + MRR+R E  VELRKNKR+E L KRRN+P  +  ++++I+   ++ N  L  IV N+++ N  ++L A+QAARKLLSSD+NPPID+LI+SGI+PILV CL+ D +P++QFEAAWALTNIASGTSEQT AVVQ+ AVPLFL+LL S H NVCEQAVWALGNIIGDGP  RDY ISLGVV PLL F++  +PITFLRNVTWV+VNLCR+KDPPP   TI E+LPAL  LI + D NILVDTVWALSYLTD GN+QIQMVI++ IV  LVPLLSH +VKVQTAALRAVGNIVTGTDEQTQ VLN DALSHFP LL H KEKINKEAVWFLSNITAGNQ+QVQAVID +L+P+II+ LDKGDF TQKEAAW ISNLTISG   QVA+++QQ VIPPFC +L+V+DAQVVQVVLDG+ NILK+A D+++ +  +IEECGGL+ IEQLQ+HEN +IYKLAY+IID FF +D+++E
Sbjct:   11 RLKNFKNKGRDLETMRRQRNEVVVELRKNKRDEHLLKRRNVPHEDICEDSDIDGDYRVQNTSLEAIVQNASSDNQGIQLSAVQAARKLLSSDRNPPIDDLIKSGILPILVHCLERDDNPSLQFEAAWALTNIASGTSEQTQAVVQSNAVPLFLRLLHSPHQNVCEQAVWALGNIIGDGPQCRDYVISLGVVKPLLSFISPSIPITFLRNVTWVMVNLCRHKDPPPPMETIQEILPALCVLIHHTDVNILVDTVWALSYLTDAGNEQIQMVIDSGIVPHLVPLLSHQEVKVQTAALRAVGNIVTGTDEQTQVVLNCDALSHFPALLTHPKEKINKEAVWFLSNITAGNQQQVQAVIDANLVPMIIHLLDKGDFGTQKEAAWAISNLTISGRKDQVAYLIQQNVIPPFCNLLTVKDAQVVQVVLDGLSNILKMAEDEAETIGNLIEECGGLEKIEQLQNHENEDIYKLAYEIIDQFFSSDDIDE 492          
BLAST of Importin subunit alpha vs. Ensembl Human
Match: KPNA2 (karyopherin subunit alpha 2 [Source:HGNC Symbol;Acc:HGNC:6395])

HSP 1 Score: 465.692 bits (1197), Expect = 2.461e-155
Identity = 243/533 (45.59%), Postives = 339/533 (63.60%), Query Frame = 3
Query:   48 VSINIGSSIMSDRRNMHKNASKDTDEMRRRRVEGNVELRKNKREETLQKRRNLPSLEAD------ENEIEEPLQMGNLSEIVANSTNPNPTVRLEAIQAARKLLSSDKNPPIDNLIQSGIMPILVECLDNDAHPNIQFEAAWALTNIASGTSEQTNAVVQAGAVPLFLKLLGSTHSNVCEQAVWALGNIIGDGPTLRDYAISLGVVAPLLKFLN----ADVPITFLRNVTWVIVNLCRNKDPPPSPVTISELLPALRFLIQNIDTNILVDTVWALSYLTDGGNDQIQMVIEADIVRFLVPLLSHNDVKVQTAALRAVGNIVTGTDEQTQYVLNFDALSHFPQLLQHSKEKINKEAVWFLSNITAGNQEQVQAVIDYSLIPLIIYHLDKGDFQTQKEAAWVISNLTISGTPQQVAFVVQQGVIPPFCKMLSVRDAQVVQVVLDGILNILKVAND--QSDLVCTMIEECGGLDLIEQLQHHENGEIYKLAYDIIDNFFNDEMEETENQNGMEMRSGVDASDMNALQQNNTGGFNF 1610
            +S N  ++  + R +  KN  KD+ EMRRRR+E NVELRK K+++ + KRRN+ S   D      EN   +     ++ +IV    + N   +L+A QAARKLLS +K PPIDN+I++G++P  V  L       IQFE+AWALTNIASGTSEQT AVV  GA+P F+ LL S H+++ EQAVWALGNI GDG   RD  I  G V PLL  L     + +   +LRN+TW + NLCRNK+P P    + ++LP L  L+ + D  +L DT WA+SYLTDG N++I MV++  +V  LV LL  +++ + T ALRA+GNIVTGTDEQTQ V++  AL+ FP LL + K  I KEA W +SNITAG Q+Q+Q V+++ L+P ++  L K DF+TQKEA W ++N T  GT +Q+ ++V  G+I P   +L+ +D +++ V+LD I NI + A    +++ +  MIEECGGLD IE LQ+HEN  +YK +  +I+ +F+ E EE +N        G        +Q    G FNF
Sbjct:    1 MSTNENANTPAARLHRFKNKGKDSTEMRRRRIEVNVELRKAKKDDQMLKRRNVSSFPDDATSPLQENRNNQGTVNWSVDDIVKGINSSNVENQLQATQAARKLLSREKQPPIDNIIRAGLIPKFVSFLGRTDCSPIQFESAWALTNIASGTSEQTKAVVDGGAIPAFISLLASPHAHISEQAVWALGNIAGDGSVFRDLVIKYGAVDPLLALLAVPDMSSLACGYLRNLTWTLSNLCRNKNPAPPIDAVEQILPTLVRLLHHDDPEVLADTCWAISYLTDGPNERIGMVVKTGVVPQLVKLLGASELPIVTPALRAIGNIVTGTDEQTQVVIDAGALAVFPSLLTNPKTNIQKEATWTMSNITAGRQDQIQQVVNHGLVPFLVSVLSKADFKTQKEAVWAVTNYTSGGTVEQIVYLVHCGIIEPLMNLLTAKDTKIILVILDAISNIFQAAEKLGETEKLSIMIEECGGLDKIEALQNHENESVYKASLSLIEKYFSVEEEEDQNVVPETTSEGYTFQ----VQDGAPGTFNF 529          
BLAST of Importin subunit alpha vs. Ensembl Human
Match: KPNA2 (karyopherin subunit alpha 2 [Source:HGNC Symbol;Acc:HGNC:6395])

HSP 1 Score: 465.692 bits (1197), Expect = 2.461e-155
Identity = 243/533 (45.59%), Postives = 339/533 (63.60%), Query Frame = 3
Query:   48 VSINIGSSIMSDRRNMHKNASKDTDEMRRRRVEGNVELRKNKREETLQKRRNLPSLEAD------ENEIEEPLQMGNLSEIVANSTNPNPTVRLEAIQAARKLLSSDKNPPIDNLIQSGIMPILVECLDNDAHPNIQFEAAWALTNIASGTSEQTNAVVQAGAVPLFLKLLGSTHSNVCEQAVWALGNIIGDGPTLRDYAISLGVVAPLLKFLN----ADVPITFLRNVTWVIVNLCRNKDPPPSPVTISELLPALRFLIQNIDTNILVDTVWALSYLTDGGNDQIQMVIEADIVRFLVPLLSHNDVKVQTAALRAVGNIVTGTDEQTQYVLNFDALSHFPQLLQHSKEKINKEAVWFLSNITAGNQEQVQAVIDYSLIPLIIYHLDKGDFQTQKEAAWVISNLTISGTPQQVAFVVQQGVIPPFCKMLSVRDAQVVQVVLDGILNILKVAND--QSDLVCTMIEECGGLDLIEQLQHHENGEIYKLAYDIIDNFFNDEMEETENQNGMEMRSGVDASDMNALQQNNTGGFNF 1610
            +S N  ++  + R +  KN  KD+ EMRRRR+E NVELRK K+++ + KRRN+ S   D      EN   +     ++ +IV    + N   +L+A QAARKLLS +K PPIDN+I++G++P  V  L       IQFE+AWALTNIASGTSEQT AVV  GA+P F+ LL S H+++ EQAVWALGNI GDG   RD  I  G V PLL  L     + +   +LRN+TW + NLCRNK+P P    + ++LP L  L+ + D  +L DT WA+SYLTDG N++I MV++  +V  LV LL  +++ + T ALRA+GNIVTGTDEQTQ V++  AL+ FP LL + K  I KEA W +SNITAG Q+Q+Q V+++ L+P ++  L K DF+TQKEA W ++N T  GT +Q+ ++V  G+I P   +L+ +D +++ V+LD I NI + A    +++ +  MIEECGGLD IE LQ+HEN  +YK +  +I+ +F+ E EE +N        G        +Q    G FNF
Sbjct:    1 MSTNENANTPAARLHRFKNKGKDSTEMRRRRIEVNVELRKAKKDDQMLKRRNVSSFPDDATSPLQENRNNQGTVNWSVDDIVKGINSSNVENQLQATQAARKLLSREKQPPIDNIIRAGLIPKFVSFLGRTDCSPIQFESAWALTNIASGTSEQTKAVVDGGAIPAFISLLASPHAHISEQAVWALGNIAGDGSVFRDLVIKYGAVDPLLALLAVPDMSSLACGYLRNLTWTLSNLCRNKNPAPPIDAVEQILPTLVRLLHHDDPEVLADTCWAISYLTDGPNERIGMVVKTGVVPQLVKLLGASELPIVTPALRAIGNIVTGTDEQTQVVIDAGALAVFPSLLTNPKTNIQKEATWTMSNITAGRQDQIQQVVNHGLVPFLVSVLSKADFKTQKEAVWAVTNYTSGGTVEQIVYLVHCGIIEPLMNLLTAKDTKIILVILDAISNIFQAAEKLGETEKLSIMIEECGGLDKIEALQNHENESVYKASLSLIEKYFSVEEEEDQNVVPETTSEGYTFQ----VQDGAPGTFNF 529          
BLAST of Importin subunit alpha vs. Ensembl Human
Match: KPNA7 (karyopherin subunit alpha 7 [Source:HGNC Symbol;Acc:HGNC:21839])

HSP 1 Score: 422.935 bits (1086), Expect = 5.448e-139
Identity = 215/487 (44.15%), Postives = 313/487 (64.27%), Query Frame = 3
Query:   81 DRRNMHKNASKDTDEMRRRRVEGNVELRKNKREETLQKRRNLPSLEAD---ENEIEEPLQMGNLSEIVANSTNPNPTVRLEAIQAARKLLSSDKNPPIDNLIQSGIMPILVECLDNDAHPNIQFEAAWALTNIASGTSEQTNAVVQAGAVPLFLKLLGSTHSNVCEQAVWALGNIIGDGPTLRDYAISLGVVAPLLKFLNADVPITFLRNVTWVIVNLCRNKDPPPSPVTISELLPALRFLIQNIDTNILVDTVWALSYLTDGGNDQIQMVIEADIVRFLVPLLSHNDVKVQTAALRAVGNIVTGTDEQTQYVLNFDALSHFPQLLQHSKEKINKEAVWFLSNITAGNQEQVQAVIDYSLIPLIIYHLDKGDFQTQKEAAWVISNLTISGTPQQVAFVVQQGVIPPFCKMLSVRDAQVVQVVLDGILNILKVANDQSDL--VCTMIEECGGLDLIEQLQHHENGEIYKLAYDIIDNFFNDEMEETEN 1526
            +RR   K   KD    R++R+  ++ELRK K++E   KRRN+ S   D   E   +       L EI+    + +P +  +A Q ARK+LS +KNPP+  +I++G++P +VE L +  +P +QFEAAWALTNIASGTSEQT AVV+ GA+   ++LL S++  VCEQAVWALGNI GDGP  RD  I+   +  LL  ++  +PITFLRN+TW + NLCRNK+P P    + ++LPAL  L+Q+ D+ +L D  WALSYLTDG N +I  V+   ++  LV L++ +++ V T +LR VGNIVTGTDEQTQ  ++   L+  PQLLQH+K  I KEA W LSN+ AG    +Q ++ Y ++P ++  L  G+F+ QKEA W+++N     T  Q+  +V  GV+ P   +L+  D ++V ++LD I  IL+ A  +S+   +C +IEE GG+D IE LQ HEN +I + A +II+  F +E +E++ 
Sbjct:    9 ERRRKFKYRGKDVSLRRQQRMAVSLELRKAKKDEQTLKRRNITSFCPDTPSEKTAKGVAVSLTLGEIIKGVNSSDPVLCFQATQTARKMLSQEKNPPLKLVIEAGLIPRMVEFLKSSLYPCLQFEAAWALTNIASGTSEQTRAVVEGGAIQPLIELLSSSNVAVCEQAVWALGNIAGDGPEFRDNVITSNAIPHLLALISPTLPITFLRNITWTLSNLCRNKNPYPCDTAVKQILPALLHLLQHQDSEVLSDACWALSYLTDGSNKRIGQVVNTGVLPRLVVLMTSSELNVLTPSLRTVGNIVTGTDEQTQMAIDAGMLNVLPQLLQHNKPSIQKEAAWALSNVAAGPCHHIQQLLAYDVLPPLVALLKNGEFKVQKEAVWMVANFATGATMDQLIQLVHSGVLEPLVNLLTAPDVKIVLIILDVISCILQAAEKRSEKENLCLLIEELGGIDRIEALQLHENRQIGQSALNIIEKHFGEEEDESQT 495          
BLAST of Importin subunit alpha vs. Ensembl Celegans
Match: ima-3 (Importin subunit alpha-3 [Source:UniProtKB/Swiss-Prot;Acc:Q19969])

HSP 1 Score: 607.831 bits (1566), Expect = 0.000e+0
Identity = 311/515 (60.39%), Postives = 386/515 (74.95%), Query Frame = 3
Query:   78 SDRRNMHKNASKDTDEMRRRRVEGNVELRKNKREETLQKRRNLPSLEADENEIEE----PLQMGNLSEIVANSTNPNPTVRLEAIQAARKLLSSDKNPPIDNLIQSGIMPILVECLDNDAHPNIQFEAAWALTNIASGTSEQTNAVVQAGAVPLFLKLLGSTHSNVCEQAVWALGNIIGDGPTLRDYAISLGVVAPLLKFLNADVPITFLRNVTWVIVNLCRNKDPPPSPVTISELLPALRFLIQNIDTNILVDTVWALSYLTDGGNDQIQMVIEADIVRFLVPLLSHNDVKVQTAALRAVGNIVTGTDEQTQYVLNFDALSHFPQLLQHSKEKINKEAVWFLSNITAGNQEQVQAVIDYSLIPLIIYHLDKGDFQTQKEAAWVISNLTISGTPQQVAFVVQQGVIPPFCKMLSVRDAQVVQVVLDGILNILKVANDQSDLVCTMIEECGGLDLIEQLQHHENGEIYKLAYDIIDNFFNDEMEETENQNGMEMRSGVDASDMNALQQNNTGGFNF 1610
            S+R+  +KN +K+    + +R E  V +RK+KREE + KRRN+ +   D++E       P     L   VA + + +P  +L A+Q ARK+LS+D+NPPID+LI SGI+P+LV+CL +   PN+QFEAAWALTNIASGTSEQT AVV AGAVPLFL+LL   + NVCEQ+VWALGNIIGDGP  RDY + LG++ PLL+F+N ++PI FLRNVTWVIVNLCR KDP PSP  +  +LPAL  LI + DTNIL+DTVWALSYLTDGGN+ IQMVIEA +V  LVPLL H DVKVQTAALRAVGNIVTGTDEQTQ VL+   L   P LL H KEKINKEAVWF+SNITAGNQ+QVQ V D  ++P+II+ LD+GDF TQKEAAW ISN+TISG P QV  +V+ GV+ PFC MLS  D+Q++QVVLDGI NILK+A + ++ V + IEECGGLD IE LQ+HEN +IYKLA++IIDNFF+ + +ET N  G +  S     D+  +     GG+NF
Sbjct:    3 SNRQAYYKNNAKEQIG-KEKRNEEVVSIRKDKREEAISKRRNINTQIEDDSETSTTPPGPFDANLLRLTVAAAQSSDPAEQLTAVQQARKMLSTDRNPPIDDLIGSGILPVLVQCLSS-TDPNLQFEAAWALTNIASGTSEQTQAVVNAGAVPLFLQLLSCGNLNVCEQSVWALGNIIGDGPHFRDYCLELGILQPLLQFINPEIPIGFLRNVTWVIVNLCRCKDPAPSPAVVRTILPALSLLIHHQDTNILIDTVWALSYLTDGGNEHIQMVIEAQVVTHLVPLLGHVDVKVQTAALRAVGNIVTGTDEQTQLVLDSGVLRFMPGLLAHYKEKINKEAVWFVSNITAGNQQQVQDVFDAGIMPMIIHLLDRGDFPTQKEAAWAISNVTISGRPNQVEQMVKLGVLRPFCAMLSCTDSQIIQVVLDGINNILKMAGEAAEQVTSEIEECGGLDKIENLQNHENEDIYKLAFEIIDNFFSSD-DETGNVEGAQ--SSAFGGDVPPVPDAPNGGWNF 512          
BLAST of Importin subunit alpha vs. Ensembl Celegans
Match: ima-2 (Importin subunit alpha-2 [Source:UniProtKB/Swiss-Prot;Acc:P91276])

HSP 1 Score: 302.753 bits (774), Expect = 3.447e-93
Identity = 182/504 (36.11%), Postives = 284/504 (56.35%), Query Frame = 3
Query:   84 RRNMHKNASKDTDEMRRRRVEGNVELRKNKREETLQKRRNLPSLEA---DENEIEEPLQMGNL--SEIVAN-------STNPNPTVRLEAIQAARKLLSSDKNPPIDNLIQSGIMPILVECLDNDAHPNIQFEAAWALTNIASGTSEQTNAVVQAGAVPLFLKLLGSTHSNVCEQAVWALGNIIGDGPTLRDYAISLGVVAPLLKFLNA--DVPITFLRNVTWVIVNLCRNKDPPPSPVTISELLPALRFLIQNIDTNILVDTVWALSYLTDGGNDQIQMVIEADIVRFLVPLLSHNDVKVQTAALRAVGNIVTGTDEQTQYVLNFDALSHFPQLLQHSKEK-INKEAVWFLSNITAGNQEQVQAVIDYSLIPLIIYHLDKGDFQTQKEAAWVISNLTISGTPQQVAFVVQQGVIPPFCKMLSVRDAQVVQVVLDGILNI-LKVAN---DQSDLVCTMIEECGGLDLIEQLQHHENGEIYKLAYDIIDNFFND----EMEETEN 1526
            R   +KN +K  +E+RRRR E +VE+RK K  + + KRRN+  ++     E+E+EEP ++ +   S  ++N       S NP+    +   ++ RK LS  KNPPID +I  G++  LV+ L  + +  +Q+EAAWALTNI SG++EQT A V+AG     + L     + + EQA+WA+ NI GD   LRDY I    V  L+  +     +  + +R + W   N+CR+K+P      +  L   L  L+Q+ D  +  D  WA+SYLTDG ++QI++  E+ ++  +V      +  V   ALR +GN+ TG D  TQ V++  +L     L++ ++   I KE  W +SNI AG Q+Q+QAV+D +L+P++I  L  GD + Q EA+W +SNL   GT +QV  +++  V+P  C+ L   +  ++   L+ +  + L V N    + D++   +EE GGLD +E+LQ  ++ +IY  AY II  FF D    E E  EN
Sbjct:   21 RLQQYKNLTKH-EELRRRRTECSVEIRKQKGADMMMKRRNIVDVDEGGNSESELEEPEKISHQQSSTRLSNDEIRAILSNNPSEDDMVRCFESLRKSLSKTKNPPIDEVIHCGLLQALVQALSVE-NERVQYEAAWALTNIVSGSTEQTIAAVEAGVTIPLIHLSVHQSAQISEQALWAVANIAGDSSQLRDYVIKCHGVEALMHLMEKVDQLGDSHVRTIAWAFSNMCRHKNPHAPLEVLRVLSKGLVKLVQHTDRQVRQDACWAVSYLTDGPDEQIELARESGVLPHVVAFFKEAENLV-APALRTLGNVATGNDSLTQAVIDLGSLDEILPLMEKTRSSSIVKECCWLVSNIIAGTQKQIQAVLDANLLPVLINVLKSGDHKCQFEASWALSNLAQGGTNRQVVAMLEDNVVPALCQALLQTNTDMLNNTLETLYTLMLTVQNGYPHKVDILHDQVEENGGLDSLERLQESQSEQIYTQAYRIITQFFTDDDAGEKESHEN 521          
BLAST of Importin subunit alpha vs. Ensembl Celegans
Match: ima-1 (Importin subunit alpha-1 [Source:UniProtKB/Swiss-Prot;Acc:Q22560])

HSP 1 Score: 104.76 bits (260), Expect = 3.561e-23
Identity = 105/493 (21.30%), Postives = 220/493 (44.62%), Query Frame = 3
Query:   81 DRRNMHKNASKDTDEMRRRRVEGNVELRKNKREETLQKRRNLPSLEADENEIEEPLQMGNLSEIVANSTNPNPTVRLEAIQAARKLLSSDKNPP---IDNLIQSGIMPILVECLDNDA-HPNIQFEAAWALTNIASGTSE-------QTNAVVQAGAVPLFLKLLGSTHSNVCEQAVWALGNIIGDGPTLRDYAISLGVVAPLLKFLNADVPITFLRNVTWVIVNLCRNKDP-PPSPVTISELLPALRFLIQNIDTNILVDTVWALSYLTDGGNDQIQMVIEADIVRFLVPLLSHNDVKVQTAALRAVGNIVTGTDEQTQYVLNFDALSHFPQLLQHSKEKINKEAVWFLSNITAGNQEQVQAVIDYSLIPLIIYHLDKGDFQTQKEAAWVISNLTISGTPQQVAFVVQQGVIPPFCKMLSVRDAQVVQVVLDGILNILKVAN-----DQSDLVCTMIEECGGLDLIEQLQHHENGEIYKLAYDIIDNFFNDE 1508
            +R  M+K+  +D +EMRR+R E  V++RKN+R+E  ++ R +         ++  L     SE++ +  +   +++   I  A  +L  + N     I  L++  I+  L +   N       +   +  L  I SG  E         +  +Q+  +   +   GS+   +C+    ++   I    T R+ A+   +V+ L+     ++ I   R++ W++   C   D   P    I+ LL  +   IQ+ D  +  D   + + L +       M  +  +   LV  L ++    +      + +I+  T   T+ +++   L      +  S   +++E  + +SNI    ++ +  +I   ++  +   ++  ++++++EAA+VI +   S   + + +VV+ G++  F  +L+  D  +V  +LD I  +L+        D S+ V   +EE G  + +E L   ++ +I+  AY IID F+ D+
Sbjct:   11 ERSKMYKSNVRDQNEMRRKRREDEVQIRKNRRDEKFERNRQIT--------VQRSLSHEETSELLKSVADGLQSMQETTIHEALTVLHENLNNTVWTIHVLVKVQILHKLSDVYCNRVISQTTRLLISRTLLKI-SGIDEVKYERYSSDDRCIQS--LVFNISTYGSSEDILCD-TFQSIACFIIRSITYRNLALDCAIVSELIDASTINMSIILHRSLMWLVFLFCEKLDRCSPHVDEIAPLLEIISNGIQSTDAMVQTDAASSCASLAEWPPIYHYMS-DLKLCSKLVANLRNDKGNARPKVKAGINSIIQATGYFTEEMIDAGLLEVLKGFVNVSY--MSQEVCFIISNICVEGEQTIDKLISSGVLREVARVMEASEYRSRREAAFVICHCCASANQKHLEYVVELGMLSAFTDLLTCMDVSLVSYILDAIYLLLQFGEMRLLPDNSNPVAIKLEEIGCREKLEFLCESQSVDIHARAYTIIDRFYVDD 488          
BLAST of Importin subunit alpha vs. Ensembl Celegans
Match: ima-1 (Importin subunit alpha-1 [Source:UniProtKB/Swiss-Prot;Acc:Q22560])

HSP 1 Score: 104.76 bits (260), Expect = 3.561e-23
Identity = 105/493 (21.30%), Postives = 220/493 (44.62%), Query Frame = 3
Query:   81 DRRNMHKNASKDTDEMRRRRVEGNVELRKNKREETLQKRRNLPSLEADENEIEEPLQMGNLSEIVANSTNPNPTVRLEAIQAARKLLSSDKNPP---IDNLIQSGIMPILVECLDNDA-HPNIQFEAAWALTNIASGTSE-------QTNAVVQAGAVPLFLKLLGSTHSNVCEQAVWALGNIIGDGPTLRDYAISLGVVAPLLKFLNADVPITFLRNVTWVIVNLCRNKDP-PPSPVTISELLPALRFLIQNIDTNILVDTVWALSYLTDGGNDQIQMVIEADIVRFLVPLLSHNDVKVQTAALRAVGNIVTGTDEQTQYVLNFDALSHFPQLLQHSKEKINKEAVWFLSNITAGNQEQVQAVIDYSLIPLIIYHLDKGDFQTQKEAAWVISNLTISGTPQQVAFVVQQGVIPPFCKMLSVRDAQVVQVVLDGILNILKVAN-----DQSDLVCTMIEECGGLDLIEQLQHHENGEIYKLAYDIIDNFFNDE 1508
            +R  M+K+  +D +EMRR+R E  V++RKN+R+E  ++ R +         ++  L     SE++ +  +   +++   I  A  +L  + N     I  L++  I+  L +   N       +   +  L  I SG  E         +  +Q+  +   +   GS+   +C+    ++   I    T R+ A+   +V+ L+     ++ I   R++ W++   C   D   P    I+ LL  +   IQ+ D  +  D   + + L +       M  +  +   LV  L ++    +      + +I+  T   T+ +++   L      +  S   +++E  + +SNI    ++ +  +I   ++  +   ++  ++++++EAA+VI +   S   + + +VV+ G++  F  +L+  D  +V  +LD I  +L+        D S+ V   +EE G  + +E L   ++ +I+  AY IID F+ D+
Sbjct:   11 ERSKMYKSNVRDQNEMRRKRREDEVQIRKNRRDEKFERNRQIT--------VQRSLSHEETSELLKSVADGLQSMQETTIHEALTVLHENLNNTVWTIHVLVKVQILHKLSDVYCNRVISQTTRLLISRTLLKI-SGIDEVKYERYSSDDRCIQS--LVFNISTYGSSEDILCD-TFQSIACFIIRSITYRNLALDCAIVSELIDASTINMSIILHRSLMWLVFLFCEKLDRCSPHVDEIAPLLEIISNGIQSTDAMVQTDAASSCASLAEWPPIYHYMS-DLKLCSKLVANLRNDKGNARPKVKAGINSIIQATGYFTEEMIDAGLLEVLKGFVNVSY--MSQEVCFIISNICVEGEQTIDKLISSGVLREVARVMEASEYRSRREAAFVICHCCASANQKHLEYVVELGMLSAFTDLLTCMDVSLVSYILDAIYLLLQFGEMRLLPDNSNPVAIKLEEIGCREKLEFLCESQSVDIHARAYTIIDRFYVDD 488          
BLAST of Importin subunit alpha vs. Ensembl Celegans
Match: F53B2.5 (pep chromosome:WBcel235:IV:12528529:12531166:-1 gene:WBGene00009956.1 transcript:F53B2.5.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:F53B2.5)

HSP 1 Score: 100.908 bits (250), Expect = 3.940e-22
Identity = 88/339 (25.96%), Postives = 154/339 (45.43%), Query Frame = 3
Query:  375 IQSGIMPILV-ECLDNDAHPNIQFEAAWALTNIASGTSEQTNAVVQAGAVPLFLKLLGSTHSNVCEQAVWALGNIIGDGPTLRDYAISLGVVAP-LLKFLNADVPITF------LRNVTWVIVNLCR-NKDPPPSPVTISELLPALRFLIQNIDTNILVDT-------VWALSYLTDGGND--QIQMVIEADIV--RFLVPLLSHNDVKVQTAALRAVGNIVTGTDEQTQYVLNFDALSHFPQLLQHSKEKINKEAVWFLSNITAGNQEQVQAVID--YSLIPLIIYHLDKGDFQTQKEAAWVISNLTISGTPQQVAFVVQQGVIPPFCKMLSVRDAQV 1325
            I++G++  L  + LD D+  N    A W +TN+   + E T+  V +  + + +KL+ S ++ +  Q VWA+ NI  D  + +     L   +P LLK L  ++  ++       R + W + N+    +   PSPV  S L+ AL  ++ + D    VD        +W L+ L D   D  +I M++  + V    L   +   D     + LR +GNI  G D QT  +++         +   S E  + EA W +SN+ AG    V  ++D   +    ++  +  GD + +KE  W+I NL  +    Q   +V  G++  F  +L   D ++
Sbjct:   69 IKNGVLNALRNQTLDIDSEVN----AVWIITNMCCISQEVTHLFVNSNCLDILIKLVRSQNARLSSQTVWAIANIAADCSSCK-----LKCRSPKLLKILARNLQTSYKLDDADRRQLIWCVNNIFSGGRTTMPSPVARS-LICALSAILLDTDA---VDNMGCGSMILWTLANLVDNSLDTTRIDMLLSQNYVVEHILEKFIDQTDKSCNVSCLRLIGNIAVGNDVQTDLLVDNPKFRVVMNIAMSSPEH-HSEAAWIISNVVAGAPRHVDYIMDDPDAFYEWVMAGIHTGDKRLRKECLWIIGNLLATADEHQTYLLVSLGIVQHFPALLDFDDVRL 393          
BLAST of Importin subunit alpha vs. Ensembl Fly
Match: Kap-alpha3 (gene:FBgn0027338 transcript:FBtr0301189)

HSP 1 Score: 645.195 bits (1663), Expect = 0.000e+0
Identity = 326/486 (67.08%), Postives = 381/486 (78.40%), Query Frame = 3
Query:   66 SSIMSDRRNMHKNASKDTDEMRRRRVEGNVELRKNKREETLQKRRNLPSLEADENEIEE-PLQMGNLSEIVANSTNPNPTVRLEAIQAARKLLSSDKNPPIDNLIQSGIMPILVECLDNDAHPNIQFEAAWALTNIASGTSEQTNAVVQAGAVPLFLKLLGSTHSNVCEQAVWALGNIIGDGPTLRDYAISLGVVAPLLKFLNADVPITFLRNVTWVIVNLCRNKDPPPSPVTISELLPALRFLIQNIDTNILVDTVWALSYLTDGGNDQIQMVIEADIVRFLVPLLSHNDVKVQTAALRAVGNIVTGTDEQTQYVLNFDALSHFPQLLQHSKEKINKEAVWFLSNITAGNQEQVQAVIDYSLIPLIIYHLDKGDFQTQKEAAWVISNLTISGTPQQVAFVVQQGVIPPFCKMLSVRDAQVVQVVLDGILNILKVANDQSDLVCTMIEECGGLDLIEQLQHHENGEIYKLAYDIIDNFFNDEMEET 1520
            +S+  +R    KN  KD DEMRRRR E  VELRKNKREET+ KRRN+P+L+++ +E E+    +       A +    P  +L A+QAARKLLSSDKNPPI++LIQS I+PILVECL    H  +QFEAAWALTNIASGTS QTN VV AGAVPLFL+LL S   NVCEQAVWALGNIIGDGP LRD+ I  GVV PLL F+  D+PITFLRNVTWVIVNLCRNKDP P   TI E+LPAL  LI + DTNILVDTVWA+SYLTDGGNDQIQMVIE+ +V  L+PLL +++VKVQTAALRAVGNIVTG+DEQTQ VLN+DALS+FP LL H KEKI KEAVWFLSNITAGNQ QVQAVI+  L+P II +L KG+FQTQKEAAW ISNLTISG  +QV  ++++GVIPPFC +LS +D QV+ VVLDG+ N+LKVA+   + V   IEEC GL  IE+LQ HEN EIYKLAY+IID +F DE E+T
Sbjct:    2 TSMEQNRLQNFKNKGKDQDEMRRRRNEVTVELRKNKREETILKRRNVPNLDSNTDEEEQLSSSIDLKKLAKAAADATKPEQQLAAVQAARKLLSSDKNPPINDLIQSDILPILVECLKQHNHTMLQFEAAWALTNIASGTSAQTNEVVAAGAVPLFLQLLNSPAPNVCEQAVWALGNIIGDGPLLRDFVIKHGVVQPLLSFIKPDIPITFLRNVTWVIVNLCRNKDPAPPTATIHEILPALNVLIHHTDTNILVDTVWAISYLTDGGNDQIQMVIESGVVPKLIPLLGNSEVKVQTAALRAVGNIVTGSDEQTQVVLNYDALSYFPGLLSHPKEKIRKEAVWFLSNITAGNQSQVQAVINVGLLPKIIENLSKGEFQTQKEAAWAISNLTISGNREQVFTLIKEGVIPPFCDLLSCQDTQVINVVLDGLNNMLKVADSHVEAVANCIEECEGLAKIERLQSHENVEIYKLAYEIIDQYFTDEGEQT 487          
BLAST of Importin subunit alpha vs. Ensembl Fly
Match: Kap-alpha3 (gene:FBgn0027338 transcript:FBtr0082106)

HSP 1 Score: 645.195 bits (1663), Expect = 0.000e+0
Identity = 326/486 (67.08%), Postives = 381/486 (78.40%), Query Frame = 3
Query:   66 SSIMSDRRNMHKNASKDTDEMRRRRVEGNVELRKNKREETLQKRRNLPSLEADENEIEE-PLQMGNLSEIVANSTNPNPTVRLEAIQAARKLLSSDKNPPIDNLIQSGIMPILVECLDNDAHPNIQFEAAWALTNIASGTSEQTNAVVQAGAVPLFLKLLGSTHSNVCEQAVWALGNIIGDGPTLRDYAISLGVVAPLLKFLNADVPITFLRNVTWVIVNLCRNKDPPPSPVTISELLPALRFLIQNIDTNILVDTVWALSYLTDGGNDQIQMVIEADIVRFLVPLLSHNDVKVQTAALRAVGNIVTGTDEQTQYVLNFDALSHFPQLLQHSKEKINKEAVWFLSNITAGNQEQVQAVIDYSLIPLIIYHLDKGDFQTQKEAAWVISNLTISGTPQQVAFVVQQGVIPPFCKMLSVRDAQVVQVVLDGILNILKVANDQSDLVCTMIEECGGLDLIEQLQHHENGEIYKLAYDIIDNFFNDEMEET 1520
            +S+  +R    KN  KD DEMRRRR E  VELRKNKREET+ KRRN+P+L+++ +E E+    +       A +    P  +L A+QAARKLLSSDKNPPI++LIQS I+PILVECL    H  +QFEAAWALTNIASGTS QTN VV AGAVPLFL+LL S   NVCEQAVWALGNIIGDGP LRD+ I  GVV PLL F+  D+PITFLRNVTWVIVNLCRNKDP P   TI E+LPAL  LI + DTNILVDTVWA+SYLTDGGNDQIQMVIE+ +V  L+PLL +++VKVQTAALRAVGNIVTG+DEQTQ VLN+DALS+FP LL H KEKI KEAVWFLSNITAGNQ QVQAVI+  L+P II +L KG+FQTQKEAAW ISNLTISG  +QV  ++++GVIPPFC +LS +D QV+ VVLDG+ N+LKVA+   + V   IEEC GL  IE+LQ HEN EIYKLAY+IID +F DE E+T
Sbjct:    2 TSMEQNRLQNFKNKGKDQDEMRRRRNEVTVELRKNKREETILKRRNVPNLDSNTDEEEQLSSSIDLKKLAKAAADATKPEQQLAAVQAARKLLSSDKNPPINDLIQSDILPILVECLKQHNHTMLQFEAAWALTNIASGTSAQTNEVVAAGAVPLFLQLLNSPAPNVCEQAVWALGNIIGDGPLLRDFVIKHGVVQPLLSFIKPDIPITFLRNVTWVIVNLCRNKDPAPPTATIHEILPALNVLIHHTDTNILVDTVWAISYLTDGGNDQIQMVIESGVVPKLIPLLGNSEVKVQTAALRAVGNIVTGSDEQTQVVLNYDALSYFPGLLSHPKEKIRKEAVWFLSNITAGNQSQVQAVINVGLLPKIIENLSKGEFQTQKEAAWAISNLTISGNREQVFTLIKEGVIPPFCDLLSCQDTQVINVVLDGLNNMLKVADSHVEAVANCIEECEGLAKIERLQSHENVEIYKLAYEIIDQYFTDEGEQT 487          
BLAST of Importin subunit alpha vs. Ensembl Fly
Match: Kap-alpha3 (gene:FBgn0027338 transcript:FBtr0082108)

HSP 1 Score: 645.195 bits (1663), Expect = 0.000e+0
Identity = 326/486 (67.08%), Postives = 381/486 (78.40%), Query Frame = 3
Query:   66 SSIMSDRRNMHKNASKDTDEMRRRRVEGNVELRKNKREETLQKRRNLPSLEADENEIEE-PLQMGNLSEIVANSTNPNPTVRLEAIQAARKLLSSDKNPPIDNLIQSGIMPILVECLDNDAHPNIQFEAAWALTNIASGTSEQTNAVVQAGAVPLFLKLLGSTHSNVCEQAVWALGNIIGDGPTLRDYAISLGVVAPLLKFLNADVPITFLRNVTWVIVNLCRNKDPPPSPVTISELLPALRFLIQNIDTNILVDTVWALSYLTDGGNDQIQMVIEADIVRFLVPLLSHNDVKVQTAALRAVGNIVTGTDEQTQYVLNFDALSHFPQLLQHSKEKINKEAVWFLSNITAGNQEQVQAVIDYSLIPLIIYHLDKGDFQTQKEAAWVISNLTISGTPQQVAFVVQQGVIPPFCKMLSVRDAQVVQVVLDGILNILKVANDQSDLVCTMIEECGGLDLIEQLQHHENGEIYKLAYDIIDNFFNDEMEET 1520
            +S+  +R    KN  KD DEMRRRR E  VELRKNKREET+ KRRN+P+L+++ +E E+    +       A +    P  +L A+QAARKLLSSDKNPPI++LIQS I+PILVECL    H  +QFEAAWALTNIASGTS QTN VV AGAVPLFL+LL S   NVCEQAVWALGNIIGDGP LRD+ I  GVV PLL F+  D+PITFLRNVTWVIVNLCRNKDP P   TI E+LPAL  LI + DTNILVDTVWA+SYLTDGGNDQIQMVIE+ +V  L+PLL +++VKVQTAALRAVGNIVTG+DEQTQ VLN+DALS+FP LL H KEKI KEAVWFLSNITAGNQ QVQAVI+  L+P II +L KG+FQTQKEAAW ISNLTISG  +QV  ++++GVIPPFC +LS +D QV+ VVLDG+ N+LKVA+   + V   IEEC GL  IE+LQ HEN EIYKLAY+IID +F DE E+T
Sbjct:    2 TSMEQNRLQNFKNKGKDQDEMRRRRNEVTVELRKNKREETILKRRNVPNLDSNTDEEEQLSSSIDLKKLAKAAADATKPEQQLAAVQAARKLLSSDKNPPINDLIQSDILPILVECLKQHNHTMLQFEAAWALTNIASGTSAQTNEVVAAGAVPLFLQLLNSPAPNVCEQAVWALGNIIGDGPLLRDFVIKHGVVQPLLSFIKPDIPITFLRNVTWVIVNLCRNKDPAPPTATIHEILPALNVLIHHTDTNILVDTVWAISYLTDGGNDQIQMVIESGVVPKLIPLLGNSEVKVQTAALRAVGNIVTGSDEQTQVVLNYDALSYFPGLLSHPKEKIRKEAVWFLSNITAGNQSQVQAVINVGLLPKIIENLSKGEFQTQKEAAWAISNLTISGNREQVFTLIKEGVIPPFCDLLSCQDTQVINVVLDGLNNMLKVADSHVEAVANCIEECEGLAKIERLQSHENVEIYKLAYEIIDQYFTDEGEQT 487          
BLAST of Importin subunit alpha vs. Ensembl Fly
Match: Kap-alpha3 (gene:FBgn0027338 transcript:FBtr0082107)

HSP 1 Score: 645.195 bits (1663), Expect = 0.000e+0
Identity = 326/486 (67.08%), Postives = 381/486 (78.40%), Query Frame = 3
Query:   66 SSIMSDRRNMHKNASKDTDEMRRRRVEGNVELRKNKREETLQKRRNLPSLEADENEIEE-PLQMGNLSEIVANSTNPNPTVRLEAIQAARKLLSSDKNPPIDNLIQSGIMPILVECLDNDAHPNIQFEAAWALTNIASGTSEQTNAVVQAGAVPLFLKLLGSTHSNVCEQAVWALGNIIGDGPTLRDYAISLGVVAPLLKFLNADVPITFLRNVTWVIVNLCRNKDPPPSPVTISELLPALRFLIQNIDTNILVDTVWALSYLTDGGNDQIQMVIEADIVRFLVPLLSHNDVKVQTAALRAVGNIVTGTDEQTQYVLNFDALSHFPQLLQHSKEKINKEAVWFLSNITAGNQEQVQAVIDYSLIPLIIYHLDKGDFQTQKEAAWVISNLTISGTPQQVAFVVQQGVIPPFCKMLSVRDAQVVQVVLDGILNILKVANDQSDLVCTMIEECGGLDLIEQLQHHENGEIYKLAYDIIDNFFNDEMEET 1520
            +S+  +R    KN  KD DEMRRRR E  VELRKNKREET+ KRRN+P+L+++ +E E+    +       A +    P  +L A+QAARKLLSSDKNPPI++LIQS I+PILVECL    H  +QFEAAWALTNIASGTS QTN VV AGAVPLFL+LL S   NVCEQAVWALGNIIGDGP LRD+ I  GVV PLL F+  D+PITFLRNVTWVIVNLCRNKDP P   TI E+LPAL  LI + DTNILVDTVWA+SYLTDGGNDQIQMVIE+ +V  L+PLL +++VKVQTAALRAVGNIVTG+DEQTQ VLN+DALS+FP LL H KEKI KEAVWFLSNITAGNQ QVQAVI+  L+P II +L KG+FQTQKEAAW ISNLTISG  +QV  ++++GVIPPFC +LS +D QV+ VVLDG+ N+LKVA+   + V   IEEC GL  IE+LQ HEN EIYKLAY+IID +F DE E+T
Sbjct:    2 TSMEQNRLQNFKNKGKDQDEMRRRRNEVTVELRKNKREETILKRRNVPNLDSNTDEEEQLSSSIDLKKLAKAAADATKPEQQLAAVQAARKLLSSDKNPPINDLIQSDILPILVECLKQHNHTMLQFEAAWALTNIASGTSAQTNEVVAAGAVPLFLQLLNSPAPNVCEQAVWALGNIIGDGPLLRDFVIKHGVVQPLLSFIKPDIPITFLRNVTWVIVNLCRNKDPAPPTATIHEILPALNVLIHHTDTNILVDTVWAISYLTDGGNDQIQMVIESGVVPKLIPLLGNSEVKVQTAALRAVGNIVTGSDEQTQVVLNYDALSYFPGLLSHPKEKIRKEAVWFLSNITAGNQSQVQAVINVGLLPKIIENLSKGEFQTQKEAAWAISNLTISGNREQVFTLIKEGVIPPFCDLLSCQDTQVINVVLDGLNNMLKVADSHVEAVANCIEECEGLAKIERLQSHENVEIYKLAYEIIDQYFTDEGEQT 487          
BLAST of Importin subunit alpha vs. Ensembl Fly
Match: Kap-alpha1 (gene:FBgn0024889 transcript:FBtr0074881)

HSP 1 Score: 447.973 bits (1151), Expect = 1.184e-148
Identity = 237/519 (45.66%), Postives = 324/519 (62.43%), Query Frame = 3
Query:   72 IMSDRRNMHKNASKDTDEMRRRRVEGNVELRKNKREETLQKRRNL----------PSLEADENEIEEPLQM-------GNLSEIVANSTNPNPTV----------------RLEAIQAARKLLSSDKNPPIDNLIQSGIMPILVECLDNDAHPNIQFEAAWALTNIASGTSEQTNAVVQAGAVPLFLKLLGSTHSNVCEQAVWALGNIIGDGPTLRDYAISLGVVAPLLKFLNADVPITFLRNVTWVIVNLCRNKDPPPSPVTISELLPALRFLIQNIDTNILVDTVWALSYLTDGGNDQIQMVIEADIVRFLVPLLSHNDVKVQTAALRAVGNIVTGTDEQTQYVLNFDALSHFPQLLQHSKEKINKEAVWFLSNITAGNQEQVQAVIDYSLIPLIIYHLDKGDFQTQKEAAWVISNLTISGTPQQVAFVVQQGVIPPFCKMLSVRDAQVVQVVLDGILNILKVAND---QSDLVCTMIEECGGLDLIEQLQHHENGEIYKLAYDIIDNFFNDEMEET 1520
            + +  +  +KNA+ D+ EMRRRR E  ++LRKNKRE+ L KRRN+            +E++ +  ++   M       G  +E  A S    P+V                +LEA Q  RKLLS D NPPI+ +IQ GI+P  V  L N A+  +QFEAAW LTNIASGTS+QT  V++AGAVP+F+ LL S H +V EQAVWALGNI GD P  RD+ +  G++ PLL  L+    IT +RN  W + NLCR K PP     IS  LP L  L++  D ++L DT WA+ YL+DG ND+IQ VI+A + R LV LL H    V TAALRAVGNIVTG D+QTQ +L ++AL+    LL  + E I KE+ W +SNI AGN+EQ+QA+I+ ++ P ++  +   +F+T+KEAAW I+N T SGT +Q+ ++VQ G +PP C  L+V D+ +VQV L+ + NILK       + +     IEECGGLD IE LQ HEN +IY  ++ II+ +F +E E++
Sbjct:    1 MSASHKQRYKNAALDSTEMRRRREEVGIQLRKNKREQQLFKRRNVVLEPATSSTSAGVESNTDNEQQAADMHMADSSTGGQNEEAAGS-GAQPSVINEEMIQMLFSGRENEQLEATQKFRKLLSRDPNPPIEEVIQKGIVPQFVTFLRNSANATLQFEAAWTLTNIASGTSQQTKVVIEAGAVPIFIDLLSSPHDDVQEQAVWALGNIAGDSPMCRDHLLGSGILEPLLHVLSNSDRITMIRNAVWTLSNLCRGKSPPADFAKISHGLPILARLLKYTDADVLSDTCWAIGYLSDGPNDKIQAVIDAGVCRRLVELLLHPQQNVSTAALRAVGNIVTGDDQQTQVILGYNALTCISHLLHSTAETIKKESCWTISNIAAGNREQIQALINANIFPQLMVIMQTAEFKTRKEAAWAITNATSSGTHEQIHYLVQVGCVPPMCDFLTVVDSDIVQVALNALENILKAGEKFQTRPNPYAITIEECGGLDKIEYLQAHENRDIYHKSFYIIEQYFGNEEEDS 518          
BLAST of Importin subunit alpha vs. Ensembl Zebrafish
Match: kpna4 (karyopherin alpha 4 (importin alpha 3) [Source:ZFIN;Acc:ZDB-GENE-030131-5584])

HSP 1 Score: 674.855 bits (1740), Expect = 0.000e+0
Identity = 337/485 (69.48%), Postives = 398/485 (82.06%), Query Frame = 3
Query:   84 RRNMHKNASKDTDEMRRRRVEGNVELRKNKREETLQKRRNLPSLE-ADENEIEEPLQMGN--LSEIVANSTNPNPTVRLEAIQAARKLLSSDKNPPIDNLIQSGIMPILVECLDNDAHPNIQFEAAWALTNIASGTSEQTNAVVQAGAVPLFLKLLGSTHSNVCEQAVWALGNIIGDGPTLRDYAISLGVVAPLLKFLNADVPITFLRNVTWVIVNLCRNKDPPPSPVTISELLPALRFLIQNIDTNILVDTVWALSYLTDGGNDQIQMVIEADIVRFLVPLLSHNDVKVQTAALRAVGNIVTGTDEQTQYVLNFDALSHFPQLLQHSKEKINKEAVWFLSNITAGNQEQVQAVIDYSLIPLIIYHLDKGDFQTQKEAAWVISNLTISGTPQQVAFVVQQGVIPPFCKMLSVRDAQVVQVVLDGILNILKVANDQSDLVCTMIEECGGLDLIEQLQHHENGEIYKLAYDIIDNFF-NDEMEETEN 1526
            R    KN  +D + MRR+R E  VELRKNKR+E L KRRN+P  +  D+++     +  N  L  IV N+T+ N  ++L A+QAARKLLSSD+NPPID+LI+SGI+PILV CLD D +P++QFEAAWALTNIASGTSEQT AVVQ+ AVPLFL+LL S H NVCEQAVWALGNIIGDGP  RDY ISLGVV PLL F++  +PITFLRNVTWV+VNLCR+KDPPP   TI E+LPAL  LI + D NILVDTVWALSYLTD GN+QIQMVI++ IV +LVPLLSH +VKVQTAALRAVGNIVTGTDEQTQ VLN DAL HFP LL H KEKINKEAVWFLSNITAGNQ+QVQAVID +L+P+II  LDKGDF TQKEAAW ISNLTISG   QVA+++QQ VIPPFC +L+V+DAQVVQVVLDG+ NILK+A+D+++ V  +IEECGGL+ IEQLQ+HEN +IYKLAY+IID FF +D+++E  N
Sbjct:   11 RLKNFKNKGRDLETMRRQRTEVVVELRKNKRDEHLLKRRNVPHEDICDDSDAVGDFRSQNTSLEAIVQNATSDNQGIQLSAVQAARKLLSSDRNPPIDDLIKSGILPILVHCLDRDDNPSLQFEAAWALTNIASGTSEQTQAVVQSNAVPLFLRLLHSPHQNVCEQAVWALGNIIGDGPQCRDYVISLGVVKPLLSFISPSIPITFLRNVTWVMVNLCRHKDPPPPMETIQEILPALCVLIHHTDVNILVDTVWALSYLTDAGNEQIQMVIDSGIVPYLVPLLSHQEVKVQTAALRAVGNIVTGTDEQTQVVLNCDALGHFPALLTHPKEKINKEAVWFLSNITAGNQQQVQAVIDANLVPMIILLLDKGDFGTQKEAAWAISNLTISGRKDQVAYLIQQQVIPPFCNLLTVKDAQVVQVVLDGLSNILKMADDEAETVANLIEECGGLEKIEQLQNHENEDIYKLAYEIIDQFFSSDDIDEDSN 495          
BLAST of Importin subunit alpha vs. Ensembl Zebrafish
Match: kpna3 (karyopherin alpha 3 (importin alpha 4) [Source:ZFIN;Acc:ZDB-GENE-030616-541])

HSP 1 Score: 656.366 bits (1692), Expect = 0.000e+0
Identity = 325/482 (67.43%), Postives = 391/482 (81.12%), Query Frame = 3
Query:   84 RRNMHKNASKDTDEMRRRRVEGNVELRKNKREETLQKRRNLPSLEA-DENEIEEPLQMGN--LSEIVANSTNPNPTVRLEAIQAARKLLSSDKNPPIDNLIQSGIMPILVECLDNDAHPNIQFEAAWALTNIASGTSEQTNAVVQAGAVPLFLKLLGSTHSNVCEQAVWALGNIIGDGPTLRDYAISLGVVAPLLKFLNADVPITFLRNVTWVIVNLCRNKDPPPSPVTISELLPALRFLIQNIDTNILVDTVWALSYLTDGGNDQIQMVIEADIVRFLVPLLSHNDVKVQTAALRAVGNIVTGTDEQTQYVLNFDALSHFPQLLQHSKEKINKEAVWFLSNITAGNQEQVQAVIDYSLIPLIIYHLDKGDFQTQKEAAWVISNLTISGTPQQVAFVVQQGVIPPFCKMLSVRDAQVVQVVLDGILNILKVANDQSDLVCTMIEECGGLDLIEQLQHHENGEIYKLAYDIIDNFFN-DEMEE 1517
            R    KN  +D + MRR R E  VELRKNKR+E L K+RN+P  E+ ++++++   +  N  L  I+ N+T+ N  V+L A+QAARKLLSSD+NPPID+LI+ GI+PILV+CL+ D +P++QFEAAWALTNIASGTS QT AVV++ AVPLFL+LL S H NVCEQAVWALGNIIGDGP  RDY ISLGVV PLL F+N  +PITFLRNVTWVIVNLCRNKDPPP   T+ E+LPAL  LI + D NILVDTVWALSYLTDGGN+QIQMVI++ +V +LVPLLSH +VKVQTAALRAVGNIVTGTDEQTQ VLN D L+HF  LL H KEKINKEAVWFLSNITAGNQ+QVQAVID  LIP+II+ L KGDF TQKEAAW ISNLTISG   QV ++VQQ VIPPFC +LSV+D+QVVQVVLDG+ NIL +A +++  +  +IEECGGL+ IE LQ HEN +IYKLA++IID +F+ D+++E
Sbjct:   11 RIKSFKNKGRDVETMRRHRNEVTVELRKNKRDEHLLKKRNVPQEESLEDSDVDSDFKGQNVTLDAILQNATSDNAVVQLSAVQAARKLLSSDRNPPIDDLIKCGILPILVKCLERDDNPSLQFEAAWALTNIASGTSAQTQAVVKSNAVPLFLRLLHSPHQNVCEQAVWALGNIIGDGPQCRDYVISLGVVKPLLSFINPSIPITFLRNVTWVIVNLCRNKDPPPPMETVQEILPALCVLIYHTDINILVDTVWALSYLTDGGNEQIQMVIDSGVVPYLVPLLSHQEVKVQTAALRAVGNIVTGTDEQTQVVLNCDVLTHFSTLLTHPKEKINKEAVWFLSNITAGNQQQVQAVIDAGLIPMIIHQLAKGDFGTQKEAAWAISNLTISGRKDQVEYLVQQNVIPPFCNLLSVKDSQVVQVVLDGLKNILIMAGEEASTIAEIIEECGGLEKIENLQQHENEDIYKLAFEIIDQYFSGDDIDE 492          
BLAST of Importin subunit alpha vs. Ensembl Zebrafish
Match: kpna2 (karyopherin alpha 2 (RAG cohort 1, importin alpha 1) [Source:ZFIN;Acc:ZDB-GENE-040718-22])

HSP 1 Score: 465.692 bits (1197), Expect = 1.193e-155
Identity = 239/495 (48.28%), Postives = 322/495 (65.05%), Query Frame = 3
Query:   84 RRNMHKNASKDTDEMRRRRVEGNVELRKNKREETLQKRRNLPSLEADENEIEEPLQMGN---------LSEIVANSTNPNPTVRLEAIQAARKLLSSDKNPPIDNLIQSGIMPILVECLDNDAHPNIQFEAAWALTNIASGTSEQTNAVVQAGAVPLFLKLLGSTHSNVCEQAVWALGNIIGDGPTLRDYAISLGVVAPLLKFLNAD----VPITFLRNVTWVIVNLCRNKDPPPSPVTISELLPALRFLIQNIDTNILVDTVWALSYLTDGGNDQIQMVIEADIVRFLVPLLSHNDVKVQTAALRAVGNIVTGTDEQTQYVLNFDALSHFPQLLQHSKEKINKEAVWFLSNITAGNQEQVQAVIDYSLIPLIIYHLDKGDFQTQKEAAWVISNLTISGTPQQVAFVVQQGVIPPFCKMLSVRDAQVVQVVLDGILNILKVANDQSDL--VCTMIEECGGLDLIEQLQHHENGEIYKLAYDIIDNFFNDEMEETE 1523
            R    KN  KD  E+RRRR+E NVELRK K++E + KRRN+ S     +E   PLQ  +         + EIV    + N   +++A QAARKLLS +++PPID +I +G++P  V  L     P IQFEAAWALTNIASGTS+QT+AVVQ GA+P F+ L+ S H+++ EQAVWALGNI GDG   RD  I  G + PLL  L        P  +LRNVTW + NLCRNK+P P    + ++LP L  L+Q+ D  +L DT WA+SYLTDG ND+I++V+ A +V  LV LL+  ++ + T +LR++GNIVTGTDEQTQ VL   AL  FP LL+H K  I KEA W LSNITAG   Q+Q VI+  ++P ++  L +GD++TQKEA W ++N T  GT +QV ++VQ  V+ P   +LS +D++ + V+LD I NI        ++  +C MIEECGGLD IE LQ HEN  +YK + ++I+ +F+ E EE E
Sbjct:   10 RLTQFKNKGKDATELRRRRIEVNVELRKAKKDEQILKRRNVSSFP---DEATSPLQEKSQNCQAQHWTVEEIVNGVNSNNLETQVQATQAARKLLSRERHPPIDRIISAGLIPKFVGFLSLVDSPPIQFEAAWALTNIASGTSDQTSAVVQGGAIPAFISLISSPHAHISEQAVWALGNIAGDGSGYRDRVIKHGAIPPLLALLAVPDLSVFPAGYLRNVTWTLSNLCRNKNPAPPLEAVKQILPTLICLLQHSDKEVLADTCWAISYLTDGPNDRIEVVVNAGVVPRLVQLLASGELSIVTPSLRSIGNIVTGTDEQTQAVLEAGALPMFPALLRHQKSNIQKEASWTLSNITAGRDYQIQEVINAGIVPYLVEVLRRGDYKTQKEAVWAVTNYTSGGTVEQVVYLVQANVLEPLLNLLSTKDSKTILVILDAITNIFLAGEKIGEVEKLCLMIEECGGLDKIEALQSHENEMVYKASLNLIEKYFSGEEEEDE 501          
BLAST of Importin subunit alpha vs. Ensembl Zebrafish
Match: kpna6 (karyopherin alpha 6 (importin alpha 7) [Source:ZFIN;Acc:ZDB-GENE-130530-626])

HSP 1 Score: 425.631 bits (1093), Expect = 5.895e-140
Identity = 233/502 (46.41%), Postives = 322/502 (64.14%), Query Frame = 3
Query:   84 RRNMHKNASKDTDEMRRRRVEGNVELRKNKREETLQKRRNLPSLEADENEIEEPLQMGNLSEIVANSTNPN---------------PTVRLEAIQAARKLLSSDKNPPIDNLIQS-GIMPILVECLDNDAHPNIQFEAAWALTNIASGTSEQTNAVVQAGAVPLFLKLLGSTHSNVCEQAVWALGNIIGDGPTLRDYAISLGVVAPLLKFLNADVPITFLRNVTWVIVNLCRNKDPPPSPVTISELLPALRFLIQNIDTNILVDTVWALSYLTDGGNDQIQMVIEADIVRFLVPLLSHNDVKVQTAALRAVGNIVTGTDEQTQYVLNFDALSHFPQLLQHSKEKINKEAVWFLSNITAGNQEQVQAVIDYSLIPLIIYHLDKGDFQTQKEAAWVISNLTISGTPQQVAFVVQQGVIPPFCKMLSVRDAQVVQVVLDGILNILKVANDQS-------DLVCTMIEECGGLDLIEQLQHHENGEIYKLAYDIIDNFFNDEMEET 1520
            R N +KN + + +EMRRRR E  ++LRK KRE+ L KRRN+  L  +    + PL    +   V+++T P+               P ++L   Q  RKLLS + NPPID +I + G++   VE L    +  +QFEAAWALTNIASGTS+QT  V++AGAVP+F++LL S   +V EQAVWALGNI GD    RDY ++  ++ PLL  L     +T  RN  W + NLCR K PPP    +S  LP L  L+ + D+++L D  WALSYL+DG N++IQ VI++ + R LV LL H+D KV + +LRAVGNIVTG D QTQ VLN  AL     LL  +KE I KEA W +SNITAGN+ Q+QAVID ++ P++I  L K +F+T+KEAAW I+N T  GTP+Q+ ++V  G I P C +L+V D+++V V L+G+ NIL++   ++       +  C++IEE  GLD IE LQ HEN EIY+ A+D+I+++F  E E+ 
Sbjct:   13 RMNRYKNKALNLEEMRRRREEEGIQLRKQKREQQLFKRRNVELLGEEGGMFDSPL----MDSYVSSTTAPDGVITRDMVEMLFSEDPELQLVTTQRFRKLLSKEPNPPIDEVISTPGVVNRFVEFLQKSTNCTLQFEAAWALTNIASGTSQQTKFVIEAGAVPVFIELLNSDFEDVQEQAVWALGNIAGDSAVCRDYVLNCNILPPLLVLLTKSTRLTMTRNAVWALSNLCRGKSPPPDFEKVSPCLPVLSRLLFSSDSDLLADACWALSYLSDGPNEKIQAVIDSGVCRRLVELLMHSDYKVASPSLRAVGNIVTGDDIQTQVVLNCSALPCLLHLLSSAKESIRKEACWTISNITAGNRAQIQAVIDANIFPVLIEILQKAEFRTRKEAAWAITNATSGGTPEQIRYLVNLGCIKPLCDLLTVMDSKIVLVALNGLENILRLGEQEAKQNGSGLNPYCSLIEEAYGLDKIEFLQSHENQEIYQKAFDLIEHYFGVEEEDA 510          
BLAST of Importin subunit alpha vs. Ensembl Zebrafish
Match: kpna5 (karyopherin alpha 5 (importin alpha 6) [Source:NCBI gene;Acc:553205])

HSP 1 Score: 416.772 bits (1070), Expect = 2.095e-136
Identity = 233/500 (46.60%), Postives = 317/500 (63.40%), Query Frame = 3
Query:   84 RRNMHKNASKDTDEMRRRRVEGNVELRKNKREETLQKRRNLPSLEADENEIEEPLQMGNLSEIVANST-------------NPNPTVRLEAIQAARKLLSSDKNPPIDNLIQS-GIMPILVECLDNDAHPNIQFEAAWALTNIASGTSEQTNAVVQAGAVPLFLKLLGSTHSNVCEQAVWALGNIIGDGPTLRDYAISLGVVAPLLKFLNADVPITFLRNVTWVIVNLCRNKDPPPSPVTISELLPALRFLIQNIDTNILVDTVWALSYLTDGGNDQIQMVIEADIVRFLVPLLSHNDVKVQTAALRAVGNIVTGTDEQTQYVLNFDALSHFPQLLQHSKEKINKEAVWFLSNITAGNQEQVQAVIDYSLIPLIIYHLDKGDFQTQKEAAWVISNLTISGTPQQVAFVVQQGVIPPFCKMLSVRDAQVVQVVLDGILNILKVANDQS-------DLVCTMIEECGGLDLIEQLQHHENGEIYKLAYDIIDNFFNDEMEET 1520
            R   +KN + +  EMRRRR E  ++LRK KREE L KRRN+     DE+ +E P+Q  ++S  V  S              + +P  +L A Q  RKLLS + NPPID +I + G++   VE L    +  +QFEAAWALTNIASGT + T  V++ GAVP+F++LL S + +V EQAVWALGNI GD    RDY ++ G++  L + L     +T  RN  W + NLCR K+PPP    +S  L  L  L+ + D ++L D  WALSYL+DG ND+IQ VI++ + R LV LL H+D KV + ALRAVGNIVTG D QTQ +LN  AL     LL   KE I KEA W +SNITAGN+ Q+QAVID ++ P++I  L K +F+T+KEAAW I+N T  GTP+Q+ ++V    I P C +L+V D+++VQV L+G+ NIL++   +S       +  C +IEE  GLD IE LQ HEN EIY+ A+D+I+++F  E E+ 
Sbjct:   13 RMKSYKNKALNPQEMRRRREEEGIQLRKQKREEQLFKRRNVSLPPGDESMLECPIQDPDVSSTVPVSGEGVITQDVIQMIFSEDPDQQLIATQKFRKLLSKEPNPPIDEVIGTPGVVNRFVEFLRRSDNCTLQFEAAWALTNIASGTFQHTKVVIETGAVPIFIELLNSEYEDVQEQAVWALGNIAGDNAECRDYVLNCGILPSLQQLLAKSNRLTTTRNAVWALSNLCRGKNPPPDFAKVSPCLSVLSRLLFSSDPDVLADACWALSYLSDGPNDKIQTVIDSGVCRRLVELLMHSDYKVVSPALRAVGNIVTGDDIQTQVILNCSALPCLLHLLSSPKESIKKEACWTVSNITAGNRAQIQAVIDSNVFPVLIEILQKAEFRTRKEAAWAITNATSGGTPEQIRYLVSLNTIKPMCDLLTVMDSKIVQVALNGLENILRLGEQESKQNGTGINPYCALIEEAYGLDKIEFLQSHENQEIYQKAFDLIEHYFGVEEEDA 512          
BLAST of Importin subunit alpha vs. Ensembl Xenopus
Match: kpna3 (karyopherin alpha 3 (importin alpha 4) [Source:NCBI gene;Acc:548814])

HSP 1 Score: 667.537 bits (1721), Expect = 0.000e+0
Identity = 331/485 (68.25%), Postives = 395/485 (81.44%), Query Frame = 3
Query:   84 RRNMHKNASKDTDEMRRRRVEGNVELRKNKREETLQKRRNLPSLEA-DENEIEEPLQMGN--LSEIVANSTNPNPTVRLEAIQAARKLLSSDKNPPIDNLIQSGIMPILVECLDNDAHPNIQFEAAWALTNIASGTSEQTNAVVQAGAVPLFLKLLGSTHSNVCEQAVWALGNIIGDGPTLRDYAISLGVVAPLLKFLNADVPITFLRNVTWVIVNLCRNKDPPPSPVTISELLPALRFLIQNIDTNILVDTVWALSYLTDGGNDQIQMVIEADIVRFLVPLLSHNDVKVQTAALRAVGNIVTGTDEQTQYVLNFDALSHFPQLLQHSKEKINKEAVWFLSNITAGNQEQVQAVIDYSLIPLIIYHLDKGDFQTQKEAAWVISNLTISGTPQQVAFVVQQGVIPPFCKMLSVRDAQVVQVVLDGILNILKVANDQSDLVCTMIEECGGLDLIEQLQHHENGEIYKLAYDIIDNFFN-DEMEETEN 1526
            R    KN  +D + MRR R E  VELRKNKR+E L K+RN+P  E+ ++++++   +  N  L  I+ N+T+ NP ++L A+QAARKLLSSD+NPPID+LI+SGI+PILV+CL+ D +P++QFEAAWALTNIASGTS QT AVVQ+ AVPLFL+LL S H NVCEQAVWALGNIIGDGP  RDY ISLGVV PLL F+N  +PITFLRNVTWVIVNLCRNKDPPP   T+ E+LPAL  LI + D NILVDTVWALSYLTDGGN+QIQMVI++ +V FLVPLLSH +VKVQTAALRAVGNIVTGTDEQTQ VLN D LSHF  LL H KEKINKEAVWFLSNITAGNQ+QVQAVID  LIP+II+ L KGDF TQKEAAW ISNLTISG   QV ++VQQ VIPPFC +LSV+D+QVVQVVLDG+ NIL +A D++  +  +IEECGGL+ IE LQ HEN EIYKLA++IID +F+ D+++E ++
Sbjct:   11 RIKSFKNKGRDVETMRRHRNEVTVELRKNKRDEHLLKKRNVPQEESLEDSDVDGDFKSQNVTLEAILQNATSDNPAIQLSAVQAARKLLSSDRNPPIDDLIKSGILPILVKCLEADDNPSLQFEAAWALTNIASGTSAQTQAVVQSNAVPLFLRLLHSLHQNVCEQAVWALGNIIGDGPQCRDYVISLGVVKPLLSFINPSIPITFLRNVTWVIVNLCRNKDPPPPMETVQEILPALCVLIYHTDINILVDTVWALSYLTDGGNEQIQMVIDSGVVPFLVPLLSHQEVKVQTAALRAVGNIVTGTDEQTQVVLNCDVLSHFHNLLTHPKEKINKEAVWFLSNITAGNQQQVQAVIDAGLIPMIIHQLAKGDFGTQKEAAWAISNLTISGRKDQVEYLVQQNVIPPFCSLLSVKDSQVVQVVLDGLKNILIMAGDEASTIAEIIEECGGLEKIEALQQHENEEIYKLAFEIIDQYFSGDDIDEDQS 495          
BLAST of Importin subunit alpha vs. Ensembl Xenopus
Match: kcnn1 (potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 1 [Source:Xenbase;Acc:XB-GENE-1001815])

HSP 1 Score: 663.3 bits (1710), Expect = 0.000e+0
Identity = 328/484 (67.77%), Postives = 398/484 (82.23%), Query Frame = 3
Query:   84 RRNMHKNASKDTDEMRRRRVEGNVELRKNKREETLQKRRNLPSLE-ADENEIEEPLQMGN--LSEIVANSTNPNPTVRLEAIQAARKLLSSDKNPPIDNLIQSGIMPILVECLDNDAHPNIQFEAAWALTNIASGTSEQTNAVVQAGAVPLFLKLLGSTHSNVCEQAVWALGNIIGDGPTLRDYAISLGVVAPLLKFLNADVPITFLRNVTWVIVNLCRNKDPPPSPVTISELLPALRFLIQNIDTNILVDTVWALSYLTDGGNDQIQMVIEADIVRFLVPLLSHNDVKVQTAALRAVGNIVTGTDEQTQYVLNFDALSHFPQLLQHSKEKINKEAVWFLSNITAGNQEQVQAVIDYSLIPLIIYHLDKGDFQTQKEAAWVISNLTISGTPQQVAFVVQQGVIPPFCKMLSVRDAQVVQVVLDGILNILKVANDQSDLVCTMIEECGGLDLIEQLQHHENGEIYKLAYDIIDNFFNDEMEETEN 1526
            R    KN  +D + MRR+R E  VELRKNKR+E L KRRN+P  +  ++++++   ++ N  L  IV N+++ +  ++L A+QAARKLLSSD+NPPID+LI+SGI+PILV CL+ D +P++QFEAAWALTNIASGTSEQT AVVQ+ AVPLFL+LL S H NVCEQAVWALGNIIGDGP  RDY ISLGVV PLL F+N  +PITFLRNVTWV+VNLCR+KDPPP   TI E+LPAL  LI + D NILVDTVWALSYLTD GN+QIQMVI++ IV  LVPLLS+ +VKVQTAALRAVGNIVTGTDEQTQ VLN DAL HFP LL H+KEKINKEAVWFLSNITAGNQ+QVQAVID +L+P+II+ LDKGDF TQKEAAW ISNLTISG   QVA+++QQ VIPPFC +L+V+D QV+QVVLDG+ NILK+A++ S+ +  +IEECGGL+ IEQLQ HEN +IYKLA++IID FF+ +++E  N
Sbjct:   11 RLKNFKNKGRDLESMRRQRNEVVVELRKNKRDEHLLKRRNVPHEDICEDSDVDADFRVQNTSLEAIVQNASSDHQGIQLSAVQAARKLLSSDRNPPIDDLIKSGILPILVHCLERDDNPSLQFEAAWALTNIASGTSEQTQAVVQSNAVPLFLRLLHSPHQNVCEQAVWALGNIIGDGPQCRDYVISLGVVKPLLSFINPSIPITFLRNVTWVMVNLCRHKDPPPPMETIQEILPALCVLIHHTDVNILVDTVWALSYLTDAGNEQIQMVIDSGIVTNLVPLLSNPEVKVQTAALRAVGNIVTGTDEQTQVVLNCDALLHFPALLTHAKEKINKEAVWFLSNITAGNQQQVQAVIDANLVPMIIHLLDKGDFGTQKEAAWAISNLTISGRKDQVAYLIQQNVIPPFCNLLTVKDPQVIQVVLDGLSNILKMADEDSETIANLIEECGGLEKIEQLQSHENEDIYKLAFEIIDQFFSSDIDEDSN 494          
BLAST of Importin subunit alpha vs. Ensembl Xenopus
Match: kcnn1 (potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 1 [Source:Xenbase;Acc:XB-GENE-1001815])

HSP 1 Score: 658.292 bits (1697), Expect = 0.000e+0
Identity = 328/496 (66.13%), Postives = 401/496 (80.85%), Query Frame = 3
Query:   63 GSSIMSD-------RRNMHKNASKDTDEMRRRRVEGNVELRKNKREETLQKRRNLPSLE-ADENEIEEPLQMGNLSEIVANSTNPNPTVRLEAIQAARKLLSSDKNPPIDNLIQSGIMPILVECLDNDAHPNIQFEAAWALTNIASGTSEQTNAVVQAGAVPLFLKLLGSTHSNVCEQAVWALGNIIGDGPTLRDYAISLGVVAPLLKFLNADVPITFLRNVTWVIVNLCRNKDPPPSPVTISELLPALRFLIQNIDTNILVDTVWALSYLTDGGNDQIQMVIEADIVRFLVPLLSHNDVKVQTAALRAVGNIVTGTDEQTQYVLNFDALSHFPQLLQHSKEKINKEAVWFLSNITAGNQEQVQAVIDYSLIPLIIYHLDKGDFQTQKEAAWVISNLTISGTPQQVAFVVQQGVIPPFCKMLSVRDAQVVQVVLDGILNILKVANDQSDLVCTMIEECGGLDLIEQLQHHENGEIYKLAYDIIDNFFNDEMEETEN 1526
            G+ IM+D       R    KN  +D + MRR+R E  VELRKNKR+E L KRRN+P  +  ++++++   ++     +  N+++ +  ++L A+QAARKLLSSD+NPPID+LI+SGI+PILV CL+ D +P++QFEAAWALTNIASGTSEQT AVVQ+ AVPLFL+LL S H NVCEQAVWALGNIIGDGP  RDY ISLGVV PLL F+N  +PITFLRNVTWV+VNLCR+KDPPP   TI E+LPAL  LI + D NILVDTVWALSYLTD GN+QIQMVI++ IV  LVPLLS+ +VKVQTAALRAVGNIVTGTDEQTQ VLN DAL HFP LL H+KEKINKEAVWFLSNITAGNQ+QVQAVID +L+P+II+ LDKGDF TQKEAAW ISNLTISG   QVA+++QQ VIPPFC +L+V+D QV+QVVLDG+ NILK+A++ S+ +  +IEECGGL+ IEQLQ HEN +IYKLA++IID FF+ +++E  N
Sbjct:   27 GAPIMADNDKLDNQRLKNFKNKGRDLESMRRQRNEVVVELRKNKRDEHLLKRRNVPHEDICEDSDVDADFRVVRSRHL--NASSDHQGIQLSAVQAARKLLSSDRNPPIDDLIKSGILPILVHCLERDDNPSLQFEAAWALTNIASGTSEQTQAVVQSNAVPLFLRLLHSPHQNVCEQAVWALGNIIGDGPQCRDYVISLGVVKPLLSFINPSIPITFLRNVTWVMVNLCRHKDPPPPMETIQEILPALCVLIHHTDVNILVDTVWALSYLTDAGNEQIQMVIDSGIVTNLVPLLSNPEVKVQTAALRAVGNIVTGTDEQTQVVLNCDALLHFPALLTHAKEKINKEAVWFLSNITAGNQQQVQAVIDANLVPMIIHLLDKGDFGTQKEAAWAISNLTISGRKDQVAYLIQQNVIPPFCNLLTVKDPQVIQVVLDGLSNILKMADEDSETIANLIEECGGLEKIEQLQSHENEDIYKLAFEIIDQFFSSDIDEDSN 520          
BLAST of Importin subunit alpha vs. Ensembl Xenopus
Match: kpna3 (karyopherin alpha 3 (importin alpha 4) [Source:NCBI gene;Acc:548814])

HSP 1 Score: 656.366 bits (1692), Expect = 0.000e+0
Identity = 331/502 (65.94%), Postives = 395/502 (78.69%), Query Frame = 3
Query:   84 RRNMHKNASKDTDEMRRRRVEGNVELRKNKREETLQKRRNLPSLEA-DENEIEEPLQMGN--LSEIVANSTNPNPTVRLEAIQAARKLLSSDKNPPIDNLIQSGIMPILVECLDNDAHPNIQFEAAWALTNIASGTSEQTNAVVQAGAVPLFLKLLGSTHSNVCEQAVWALGNIIGDGPTLRDYAISLGVVAPLLKFLNADVPITFLRNVTWVIVNLCRNKDPPPSPVTISE-----------------LLPALRFLIQNIDTNILVDTVWALSYLTDGGNDQIQMVIEADIVRFLVPLLSHNDVKVQTAALRAVGNIVTGTDEQTQYVLNFDALSHFPQLLQHSKEKINKEAVWFLSNITAGNQEQVQAVIDYSLIPLIIYHLDKGDFQTQKEAAWVISNLTISGTPQQVAFVVQQGVIPPFCKMLSVRDAQVVQVVLDGILNILKVANDQSDLVCTMIEECGGLDLIEQLQHHENGEIYKLAYDIIDNFFN-DEMEETEN 1526
            R    KN  +D + MRR R E  VELRKNKR+E L K+RN+P  E+ ++++++   +  N  L  I+ N+T+ NP ++L A+QAARKLLSSD+NPPID+LI+SGI+PILV+CL+ D +P++QFEAAWALTNIASGTS QT AVVQ+ AVPLFL+LL S H NVCEQAVWALGNIIGDGP  RDY ISLGVV PLL F+N  +PITFLRNVTWVIVNLCRNKDPPP   T+ E                 +LPAL  LI + D NILVDTVWALSYLTDGGN+QIQMVI++ +V FLVPLLSH +VKVQTAALRAVGNIVTGTDEQTQ VLN D LSHF  LL H KEKINKEAVWFLSNITAGNQ+QVQAVID  LIP+II+ L KGDF TQKEAAW ISNLTISG   QV ++VQQ VIPPFC +LSV+D+QVVQVVLDG+ NIL +A D++  +  +IEECGGL+ IE LQ HEN EIYKLA++IID +F+ D+++E ++
Sbjct:   11 RIKSFKNKGRDVETMRRHRNEVTVELRKNKRDEHLLKKRNVPQEESLEDSDVDGDFKSQNVTLEAILQNATSDNPAIQLSAVQAARKLLSSDRNPPIDDLIKSGILPILVKCLEADDNPSLQFEAAWALTNIASGTSAQTQAVVQSNAVPLFLRLLHSLHQNVCEQAVWALGNIIGDGPQCRDYVISLGVVKPLLSFINPSIPITFLRNVTWVIVNLCRNKDPPPPMETVQEAFWVIADLSGKDCILGMILPALCVLIYHTDINILVDTVWALSYLTDGGNEQIQMVIDSGVVPFLVPLLSHQEVKVQTAALRAVGNIVTGTDEQTQVVLNCDVLSHFHNLLTHPKEKINKEAVWFLSNITAGNQQQVQAVIDAGLIPMIIHQLAKGDFGTQKEAAWAISNLTISGRKDQVEYLVQQNVIPPFCSLLSVKDSQVVQVVLDGLKNILIMAGDEASTIAEIIEECGGLEKIEALQQHENEEIYKLAFEIIDQYFSGDDIDEDQS 512          
BLAST of Importin subunit alpha vs. Ensembl Xenopus
Match: kcnn1 (potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 1 [Source:Xenbase;Acc:XB-GENE-1001815])

HSP 1 Score: 655.981 bits (1691), Expect = 0.000e+0
Identity = 324/482 (67.22%), Postives = 395/482 (81.95%), Query Frame = 3
Query:   84 RRNMHKNASKDTDEMRRRRVEGNVELRKNKREETLQKRRNLPSLE-ADENEIEEPLQMGNLSEIVANSTNPNPTVRLEAIQAARKLLSSDKNPPIDNLIQSGIMPILVECLDNDAHPNIQFEAAWALTNIASGTSEQTNAVVQAGAVPLFLKLLGSTHSNVCEQAVWALGNIIGDGPTLRDYAISLGVVAPLLKFLNADVPITFLRNVTWVIVNLCRNKDPPPSPVTISELLPALRFLIQNIDTNILVDTVWALSYLTDGGNDQIQMVIEADIVRFLVPLLSHNDVKVQTAALRAVGNIVTGTDEQTQYVLNFDALSHFPQLLQHSKEKINKEAVWFLSNITAGNQEQVQAVIDYSLIPLIIYHLDKGDFQTQKEAAWVISNLTISGTPQQVAFVVQQGVIPPFCKMLSVRDAQVVQVVLDGILNILKVANDQSDLVCTMIEECGGLDLIEQLQHHENGEIYKLAYDIIDNFFNDEMEETEN 1526
            R    KN  +D + MRR+R E  VELRKNKR+E L KRRN+P  +  ++++++   ++     +  N+++ +  ++L A+QAARKLLSSD+NPPID+LI+SGI+PILV CL+ D +P++QFEAAWALTNIASGTSEQT AVVQ+ AVPLFL+LL S H NVCEQAVWALGNIIGDGP  RDY ISLGVV PLL F+N  +PITFLRNVTWV+VNLCR+KDPPP   TI E+LPAL  LI + D NILVDTVWALSYLTD GN+QIQMVI++ IV  LVPLLS+ +VKVQTAALRAVGNIVTGTDEQTQ VLN DAL HFP LL H+KEKINKEAVWFLSNITAGNQ+QVQAVID +L+P+II+ LDKGDF TQKEAAW ISNLTISG   QVA+++QQ VIPPFC +L+V+D QV+QVVLDG+ NILK+A++ S+ +  +IEECGGL+ IEQLQ HEN +IYKLA++IID FF+ +++E  N
Sbjct:   11 RLKNFKNKGRDLESMRRQRNEVVVELRKNKRDEHLLKRRNVPHEDICEDSDVDADFRVVRSRHL--NASSDHQGIQLSAVQAARKLLSSDRNPPIDDLIKSGILPILVHCLERDDNPSLQFEAAWALTNIASGTSEQTQAVVQSNAVPLFLRLLHSPHQNVCEQAVWALGNIIGDGPQCRDYVISLGVVKPLLSFINPSIPITFLRNVTWVMVNLCRHKDPPPPMETIQEILPALCVLIHHTDVNILVDTVWALSYLTDAGNEQIQMVIDSGIVTNLVPLLSNPEVKVQTAALRAVGNIVTGTDEQTQVVLNCDALLHFPALLTHAKEKINKEAVWFLSNITAGNQQQVQAVIDANLVPMIIHLLDKGDFGTQKEAAWAISNLTISGRKDQVAYLIQQNVIPPFCNLLTVKDPQVIQVVLDGLSNILKMADEDSETIANLIEECGGLEKIEQLQSHENEDIYKLAFEIIDQFFSSDIDEDSN 490          
BLAST of Importin subunit alpha vs. Ensembl Mouse
Match: Kpna4 (karyopherin (importin) alpha 4 [Source:MGI Symbol;Acc:MGI:1100848])

HSP 1 Score: 672.159 bits (1733), Expect = 0.000e+0
Identity = 341/513 (66.47%), Postives = 410/513 (79.92%), Query Frame = 3
Query:   84 RRNMHKNASKDTDEMRRRRVEGNVELRKNKREETLQKRRNLPSLE-ADENEIEEPLQMGN--LSEIVANSTNPNPTVRLEAIQAARKLLSSDKNPPIDNLIQSGIMPILVECLDNDAHPNIQFEAAWALTNIASGTSEQTNAVVQAGAVPLFLKLLGSTHSNVCEQAVWALGNIIGDGPTLRDYAISLGVVAPLLKFLNADVPITFLRNVTWVIVNLCRNKDPPPSPVTISELLPALRFLIQNIDTNILVDTVWALSYLTDGGNDQIQMVIEADIVRFLVPLLSHNDVKVQTAALRAVGNIVTGTDEQTQYVLNFDALSHFPQLLQHSKEKINKEAVWFLSNITAGNQEQVQAVIDYSLIPLIIYHLDKGDFQTQKEAAWVISNLTISGTPQQVAFVVQQGVIPPFCKMLSVRDAQVVQVVLDGILNILKVANDQSDLVCTMIEECGGLDLIEQLQHHENGEIYKLAYDIIDNFF-NDEMEETENQNGMEMRSGVDASDMNALQQNNTGGFNF 1610
            R    KN  +D + MRR+R E  VELRKNKR+E L KRRN+P  +  ++++I+   ++ N  L  IV N+++ N  ++L A+QAARKLLSSD+NPPID+LI+SGI+PILV CL+ D +P++QFEAAWALTNIASGTSEQT AVVQ+ AVPLFL+LL S H NVCEQAVWALGNIIGDGP  RDY ISLGVV PLL F++  +PITFLRNVTWV+VNLCR+KDPPP   TI E+LPAL  LI + D NILVDTVWALSYLTD GN+QIQMVI++ IV  LVPLLSH +VKVQTAALRAVGNIVTGTDEQTQ VLN DALSHFP LL H KEKINKEAVWFLSNITAGNQ+QVQAVID +L+P+II+ LDKGDF TQKEAAW ISNLTISG   QVA+++QQ VIPPFC +L+V+DAQVVQVVLDG+ NILK+A DQ++ +  +IEECGGL+ IEQLQ+HEN +IYKLAY+IID FF +D+++E  +     ++ G      N+     T GF F
Sbjct:   11 RLKNFKNKGRDLETMRRQRNEVVVELRKNKRDEHLLKRRNVPQEDICEDSDIDGDYRVQNTSLEAIVQNASSDNQGIQLSAVQAARKLLSSDRNPPIDDLIKSGILPILVHCLERDDNPSLQFEAAWALTNIASGTSEQTQAVVQSNAVPLFLRLLHSPHQNVCEQAVWALGNIIGDGPQCRDYVISLGVVKPLLSFISPSIPITFLRNVTWVMVNLCRHKDPPPPMETIQEILPALCVLIHHTDVNILVDTVWALSYLTDAGNEQIQMVIDSGIVPHLVPLLSHQEVKVQTAALRAVGNIVTGTDEQTQVVLNCDALSHFPALLTHPKEKINKEAVWFLSNITAGNQQQVQAVIDANLVPMIIHLLDKGDFGTQKEAAWAISNLTISGRKDQVAYLIQQNVIPPFCNLLTVKDAQVVQVVLDGLSNILKMAEDQAETIANLIEECGGLEKIEQLQNHENEDIYKLAYEIIDQFFSSDDIDEDPSLVPESVQGGTFG--FNSSTNVPTEGFQF 521          
BLAST of Importin subunit alpha vs. Ensembl Mouse
Match: Kpna4 (karyopherin (importin) alpha 4 [Source:MGI Symbol;Acc:MGI:1100848])

HSP 1 Score: 672.159 bits (1733), Expect = 0.000e+0
Identity = 341/513 (66.47%), Postives = 410/513 (79.92%), Query Frame = 3
Query:   84 RRNMHKNASKDTDEMRRRRVEGNVELRKNKREETLQKRRNLPSLE-ADENEIEEPLQMGN--LSEIVANSTNPNPTVRLEAIQAARKLLSSDKNPPIDNLIQSGIMPILVECLDNDAHPNIQFEAAWALTNIASGTSEQTNAVVQAGAVPLFLKLLGSTHSNVCEQAVWALGNIIGDGPTLRDYAISLGVVAPLLKFLNADVPITFLRNVTWVIVNLCRNKDPPPSPVTISELLPALRFLIQNIDTNILVDTVWALSYLTDGGNDQIQMVIEADIVRFLVPLLSHNDVKVQTAALRAVGNIVTGTDEQTQYVLNFDALSHFPQLLQHSKEKINKEAVWFLSNITAGNQEQVQAVIDYSLIPLIIYHLDKGDFQTQKEAAWVISNLTISGTPQQVAFVVQQGVIPPFCKMLSVRDAQVVQVVLDGILNILKVANDQSDLVCTMIEECGGLDLIEQLQHHENGEIYKLAYDIIDNFF-NDEMEETENQNGMEMRSGVDASDMNALQQNNTGGFNF 1610
            R    KN  +D + MRR+R E  VELRKNKR+E L KRRN+P  +  ++++I+   ++ N  L  IV N+++ N  ++L A+QAARKLLSSD+NPPID+LI+SGI+PILV CL+ D +P++QFEAAWALTNIASGTSEQT AVVQ+ AVPLFL+LL S H NVCEQAVWALGNIIGDGP  RDY ISLGVV PLL F++  +PITFLRNVTWV+VNLCR+KDPPP   TI E+LPAL  LI + D NILVDTVWALSYLTD GN+QIQMVI++ IV  LVPLLSH +VKVQTAALRAVGNIVTGTDEQTQ VLN DALSHFP LL H KEKINKEAVWFLSNITAGNQ+QVQAVID +L+P+II+ LDKGDF TQKEAAW ISNLTISG   QVA+++QQ VIPPFC +L+V+DAQVVQVVLDG+ NILK+A DQ++ +  +IEECGGL+ IEQLQ+HEN +IYKLAY+IID FF +D+++E  +     ++ G      N+     T GF F
Sbjct:  113 RLKNFKNKGRDLETMRRQRNEVVVELRKNKRDEHLLKRRNVPQEDICEDSDIDGDYRVQNTSLEAIVQNASSDNQGIQLSAVQAARKLLSSDRNPPIDDLIKSGILPILVHCLERDDNPSLQFEAAWALTNIASGTSEQTQAVVQSNAVPLFLRLLHSPHQNVCEQAVWALGNIIGDGPQCRDYVISLGVVKPLLSFISPSIPITFLRNVTWVMVNLCRHKDPPPPMETIQEILPALCVLIHHTDVNILVDTVWALSYLTDAGNEQIQMVIDSGIVPHLVPLLSHQEVKVQTAALRAVGNIVTGTDEQTQVVLNCDALSHFPALLTHPKEKINKEAVWFLSNITAGNQQQVQAVIDANLVPMIIHLLDKGDFGTQKEAAWAISNLTISGRKDQVAYLIQQNVIPPFCNLLTVKDAQVVQVVLDGLSNILKMAEDQAETIANLIEECGGLEKIEQLQNHENEDIYKLAYEIIDQFFSSDDIDEDPSLVPESVQGGTFG--FNSSTNVPTEGFQF 623          
BLAST of Importin subunit alpha vs. Ensembl Mouse
Match: Kpna3 (karyopherin (importin) alpha 3 [Source:MGI Symbol;Acc:MGI:1100863])

HSP 1 Score: 669.463 bits (1726), Expect = 0.000e+0
Identity = 342/513 (66.67%), Postives = 401/513 (78.17%), Query Frame = 3
Query:   84 RRNMHKNASKDTDEMRRRRVEGNVELRKNKREETLQKRRNLP---SLEADENEIEEPLQMGNLSEIVANSTNPNPTVRLEAIQAARKLLSSDKNPPIDNLIQSGIMPILVECLDNDAHPNIQFEAAWALTNIASGTSEQTNAVVQAGAVPLFLKLLGSTHSNVCEQAVWALGNIIGDGPTLRDYAISLGVVAPLLKFLNADVPITFLRNVTWVIVNLCRNKDPPPSPVTISELLPALRFLIQNIDTNILVDTVWALSYLTDGGNDQIQMVIEADIVRFLVPLLSHNDVKVQTAALRAVGNIVTGTDEQTQYVLNFDALSHFPQLLQHSKEKINKEAVWFLSNITAGNQEQVQAVIDYSLIPLIIYHLDKGDFQTQKEAAWVISNLTISGTPQQVAFVVQQGVIPPFCKMLSVRDAQVVQVVLDGILNILKVANDQSDLVCTMIEECGGLDLIEQLQHHENGEIYKLAYDIIDNFFN-DEMEETENQNGMEMRSGVDASDMNALQQNNTGGFNF 1610
            R    KN  +D + MRR R E  VELRKNKR+E L K+RN+P   SLE  + + +   Q   L  I+ N+T+ NP V+L A+QAARKLLSSD+NPPID+LI+SGI+PILV+CL+ D +P++QFEAAWALTNIASGTS QT AVVQ+ AVPLFL+LL S H NVCEQAVWALGNIIGDGP  RDY ISLGVV PLL F+N  +PITFLRNVTWVIVNLCRNKDPPP   T+ E+LPAL  LI + D NILVDTVWALSYLTDGGN+QIQMVI++ +V FLVPLLSH +VKVQTAALRAVGNIVTGTDEQTQ VLN D LSHFP LL H KEKINKEAVWFLSNITAGNQ+QVQAVID  LIP+II+ L KGDF TQKEAAW ISNLTISG   QV ++VQQ VIPPFC +LSV+D+QVVQVVLDG+ NIL +A D++  +  +IEECGGL+ IE LQ HEN +IYKLA++IID +F+ D+++E  +      + G    D  A  Q  T  FNF
Sbjct:   11 RIKSFKNKGRDVETMRRHRNEVTVELRKNKRDEHLLKKRNVPQEESLEDSDVDADFKAQNVTLEAILQNATSDNPVVQLSAVQAARKLLSSDRNPPIDDLIKSGILPILVKCLERDDNPSLQFEAAWALTNIASGTSAQTQAVVQSNAVPLFLRLLHSPHQNVCEQAVWALGNIIGDGPQCRDYVISLGVVKPLLSFINPSIPITFLRNVTWVIVNLCRNKDPPPPMETVQEILPALCVLIYHTDINILVDTVWALSYLTDGGNEQIQMVIDSGVVPFLVPLLSHQEVKVQTAALRAVGNIVTGTDEQTQVVLNCDVLSHFPNLLSHPKEKINKEAVWFLSNITAGNQQQVQAVIDAGLIPMIIHQLAKGDFGTQKEAAWAISNLTISGRKDQVEYLVQQNVIPPFCNLLSVKDSQVVQVVLDGLKNILIMAGDEASTIAEIIEECGGLEKIEVLQQHENEDIYKLAFEIIDQYFSGDDIDEDPSLIPEATQGGTYNFDPTANLQ--TKEFNF 521          
BLAST of Importin subunit alpha vs. Ensembl Mouse
Match: Gm10184 (predicted pseudogene 10184 [Source:MGI Symbol;Acc:MGI:3704480])

HSP 1 Score: 474.167 bits (1219), Expect = 8.318e-159
Identity = 247/533 (46.34%), Postives = 342/533 (64.17%), Query Frame = 3
Query:   48 VSINIGSSIMSDRRNMHKNASKDTDEMRRRRVEGNVELRKNKREETLQKRRNLPSLEAD------ENEIEEPLQMGNLSEIVANSTNPNPTVRLEAIQAARKLLSSDKNPPIDNLIQSGIMPILVECLDNDAHPNIQFEAAWALTNIASGTSEQTNAVVQAGAVPLFLKLLGSTHSNVCEQAVWALGNIIGDGPTLRDYAISLGVVAPLLKFLN----ADVPITFLRNVTWVIVNLCRNKDPPPSPVTISELLPALRFLIQNIDTNILVDTVWALSYLTDGGNDQIQMVIEADIVRFLVPLLSHNDVKVQTAALRAVGNIVTGTDEQTQYVLNFDALSHFPQLLQHSKEKINKEAVWFLSNITAGNQEQVQAVIDYSLIPLIIYHLDKGDFQTQKEAAWVISNLTISGTPQQVAFVVQQGVIPPFCKMLSVRDAQVVQVVLDGILNILKVAND--QSDLVCTMIEECGGLDLIEQLQHHENGEIYKLAYDIIDNFFNDEMEETENQNGMEMRSGVDASDMNALQQNNTGGFNF 1610
            +S N  +++ + R N  KN  KD+ EMRRRR+E NVELRK K++E + KRRN+ S   D      EN   +     ++ +IV    + N   +L+A QAARKLLS +K PPIDN+I++G++P  V  L       IQFE+AWALTNIASGTSEQT AVV  GA+P F+ LL S H+++ EQAVWALGNI GDG   RD  I  G + PLL  L     + +   +LRN+TW + NLCRNK+P P    + ++LP L  L+ + D  +L D+ WA+SYLTDG N++I+MV++  +V  LV LL   ++ + T ALRA+GNIVTGTDEQTQ V++  AL+ FP LL + K  I KEA W +SNITAG Q+Q+Q V+++ L+P ++  L K DF+TQKEAAW I+N T  GT +Q+ ++V  G+I P   +LS +D +++QV+LD I NI + A    +++ +  MIEECGGLD IE LQ HEN  +YK + ++I+ +F+ E EE +N        G        +Q    G FNF
Sbjct:    1 MSTNENANLPAARLNRFKNKGKDSTEMRRRRIEVNVELRKAKKDEQMLKRRNVSSFPDDATSPLQENRNNQGTVNWSVEDIVKGINSNNLESQLQATQAARKLLSREKQPPIDNIIRAGLIPKFVSFLGKTDCSPIQFESAWALTNIASGTSEQTKAVVDGGAIPAFISLLASPHAHISEQAVWALGNIAGDGSAFRDLVIKHGAIDPLLALLAVPDLSTLACGYLRNLTWTLSNLCRNKNPAPPLDAVEQILPTLVRLLHHNDPEVLADSCWAISYLTDGPNERIEMVVKKGVVPQLVKLLGATELPIVTPALRAIGNIVTGTDEQTQKVIDAGALAVFPSLLTNPKTNIQKEATWTMSNITAGRQDQIQQVVNHGLVPFLVGVLSKADFKTQKEAAWAITNYTSGGTVEQIVYLVHCGIIEPLMNLLSAKDTKIIQVILDAISNIFQAAEKLGETEKLSIMIEECGGLDKIEALQRHENESVYKASLNLIEKYFSVEEEEDQNVVPETTSEGFAFQ----VQDGAPGTFNF 529          
BLAST of Importin subunit alpha vs. Ensembl Mouse
Match: Kpna2 (karyopherin (importin) alpha 2 [Source:MGI Symbol;Acc:MGI:103561])

HSP 1 Score: 474.167 bits (1219), Expect = 8.318e-159
Identity = 247/533 (46.34%), Postives = 342/533 (64.17%), Query Frame = 3
Query:   48 VSINIGSSIMSDRRNMHKNASKDTDEMRRRRVEGNVELRKNKREETLQKRRNLPSLEAD------ENEIEEPLQMGNLSEIVANSTNPNPTVRLEAIQAARKLLSSDKNPPIDNLIQSGIMPILVECLDNDAHPNIQFEAAWALTNIASGTSEQTNAVVQAGAVPLFLKLLGSTHSNVCEQAVWALGNIIGDGPTLRDYAISLGVVAPLLKFLN----ADVPITFLRNVTWVIVNLCRNKDPPPSPVTISELLPALRFLIQNIDTNILVDTVWALSYLTDGGNDQIQMVIEADIVRFLVPLLSHNDVKVQTAALRAVGNIVTGTDEQTQYVLNFDALSHFPQLLQHSKEKINKEAVWFLSNITAGNQEQVQAVIDYSLIPLIIYHLDKGDFQTQKEAAWVISNLTISGTPQQVAFVVQQGVIPPFCKMLSVRDAQVVQVVLDGILNILKVAND--QSDLVCTMIEECGGLDLIEQLQHHENGEIYKLAYDIIDNFFNDEMEETENQNGMEMRSGVDASDMNALQQNNTGGFNF 1610
            +S N  +++ + R N  KN  KD+ EMRRRR+E NVELRK K++E + KRRN+ S   D      EN   +     ++ +IV    + N   +L+A QAARKLLS +K PPIDN+I++G++P  V  L       IQFE+AWALTNIASGTSEQT AVV  GA+P F+ LL S H+++ EQAVWALGNI GDG   RD  I  G + PLL  L     + +   +LRN+TW + NLCRNK+P P    + ++LP L  L+ + D  +L D+ WA+SYLTDG N++I+MV++  +V  LV LL   ++ + T ALRA+GNIVTGTDEQTQ V++  AL+ FP LL + K  I KEA W +SNITAG Q+Q+Q V+++ L+P ++  L K DF+TQKEAAW I+N T  GT +Q+ ++V  G+I P   +LS +D +++QV+LD I NI + A    +++ +  MIEECGGLD IE LQ HEN  +YK + ++I+ +F+ E EE +N        G        +Q    G FNF
Sbjct:    1 MSTNENANLPAARLNRFKNKGKDSTEMRRRRIEVNVELRKAKKDEQMLKRRNVSSFPDDATSPLQENRNNQGTVNWSVEDIVKGINSNNLESQLQATQAARKLLSREKQPPIDNIIRAGLIPKFVSFLGKTDCSPIQFESAWALTNIASGTSEQTKAVVDGGAIPAFISLLASPHAHISEQAVWALGNIAGDGSAFRDLVIKHGAIDPLLALLAVPDLSTLACGYLRNLTWTLSNLCRNKNPAPPLDAVEQILPTLVRLLHHNDPEVLADSCWAISYLTDGPNERIEMVVKKGVVPQLVKLLGATELPIVTPALRAIGNIVTGTDEQTQKVIDAGALAVFPSLLTNPKTNIQKEATWTMSNITAGRQDQIQQVVNHGLVPFLVGVLSKADFKTQKEAAWAITNYTSGGTVEQIVYLVHCGIIEPLMNLLSAKDTKIIQVILDAISNIFQAAEKLGETEKLSIMIEECGGLDKIEALQRHENESVYKASLNLIEKYFSVEEEEDQNVVPETTSEGFAFQ----VQDGAPGTFNF 529          
BLAST of Importin subunit alpha vs. UniProt/SwissProt
Match: sp|O35343|IMA3_MOUSE (Importin subunit alpha-3 OS=Mus musculus OX=10090 GN=Kpna4 PE=1 SV=1)

HSP 1 Score: 672.159 bits (1733), Expect = 0.000e+0
Identity = 341/513 (66.47%), Postives = 410/513 (79.92%), Query Frame = 3
Query:   84 RRNMHKNASKDTDEMRRRRVEGNVELRKNKREETLQKRRNLPSLE-ADENEIEEPLQMGN--LSEIVANSTNPNPTVRLEAIQAARKLLSSDKNPPIDNLIQSGIMPILVECLDNDAHPNIQFEAAWALTNIASGTSEQTNAVVQAGAVPLFLKLLGSTHSNVCEQAVWALGNIIGDGPTLRDYAISLGVVAPLLKFLNADVPITFLRNVTWVIVNLCRNKDPPPSPVTISELLPALRFLIQNIDTNILVDTVWALSYLTDGGNDQIQMVIEADIVRFLVPLLSHNDVKVQTAALRAVGNIVTGTDEQTQYVLNFDALSHFPQLLQHSKEKINKEAVWFLSNITAGNQEQVQAVIDYSLIPLIIYHLDKGDFQTQKEAAWVISNLTISGTPQQVAFVVQQGVIPPFCKMLSVRDAQVVQVVLDGILNILKVANDQSDLVCTMIEECGGLDLIEQLQHHENGEIYKLAYDIIDNFF-NDEMEETENQNGMEMRSGVDASDMNALQQNNTGGFNF 1610
            R    KN  +D + MRR+R E  VELRKNKR+E L KRRN+P  +  ++++I+   ++ N  L  IV N+++ N  ++L A+QAARKLLSSD+NPPID+LI+SGI+PILV CL+ D +P++QFEAAWALTNIASGTSEQT AVVQ+ AVPLFL+LL S H NVCEQAVWALGNIIGDGP  RDY ISLGVV PLL F++  +PITFLRNVTWV+VNLCR+KDPPP   TI E+LPAL  LI + D NILVDTVWALSYLTD GN+QIQMVI++ IV  LVPLLSH +VKVQTAALRAVGNIVTGTDEQTQ VLN DALSHFP LL H KEKINKEAVWFLSNITAGNQ+QVQAVID +L+P+II+ LDKGDF TQKEAAW ISNLTISG   QVA+++QQ VIPPFC +L+V+DAQVVQVVLDG+ NILK+A DQ++ +  +IEECGGL+ IEQLQ+HEN +IYKLAY+IID FF +D+++E  +     ++ G      N+     T GF F
Sbjct:   11 RLKNFKNKGRDLETMRRQRNEVVVELRKNKRDEHLLKRRNVPQEDICEDSDIDGDYRVQNTSLEAIVQNASSDNQGIQLSAVQAARKLLSSDRNPPIDDLIKSGILPILVHCLERDDNPSLQFEAAWALTNIASGTSEQTQAVVQSNAVPLFLRLLHSPHQNVCEQAVWALGNIIGDGPQCRDYVISLGVVKPLLSFISPSIPITFLRNVTWVMVNLCRHKDPPPPMETIQEILPALCVLIHHTDVNILVDTVWALSYLTDAGNEQIQMVIDSGIVPHLVPLLSHQEVKVQTAALRAVGNIVTGTDEQTQVVLNCDALSHFPALLTHPKEKINKEAVWFLSNITAGNQQQVQAVIDANLVPMIIHLLDKGDFGTQKEAAWAISNLTISGRKDQVAYLIQQNVIPPFCNLLTVKDAQVVQVVLDGLSNILKMAEDQAETIANLIEECGGLEKIEQLQNHENEDIYKLAYEIIDQFFSSDDIDEDPSLVPESVQGGTFG--FNSSTNVPTEGFQF 521          
BLAST of Importin subunit alpha vs. UniProt/SwissProt
Match: sp|O35344|IMA4_MOUSE (Importin subunit alpha-4 OS=Mus musculus OX=10090 GN=Kpna3 PE=1 SV=1)

HSP 1 Score: 669.463 bits (1726), Expect = 0.000e+0
Identity = 342/513 (66.67%), Postives = 401/513 (78.17%), Query Frame = 3
Query:   84 RRNMHKNASKDTDEMRRRRVEGNVELRKNKREETLQKRRNLP---SLEADENEIEEPLQMGNLSEIVANSTNPNPTVRLEAIQAARKLLSSDKNPPIDNLIQSGIMPILVECLDNDAHPNIQFEAAWALTNIASGTSEQTNAVVQAGAVPLFLKLLGSTHSNVCEQAVWALGNIIGDGPTLRDYAISLGVVAPLLKFLNADVPITFLRNVTWVIVNLCRNKDPPPSPVTISELLPALRFLIQNIDTNILVDTVWALSYLTDGGNDQIQMVIEADIVRFLVPLLSHNDVKVQTAALRAVGNIVTGTDEQTQYVLNFDALSHFPQLLQHSKEKINKEAVWFLSNITAGNQEQVQAVIDYSLIPLIIYHLDKGDFQTQKEAAWVISNLTISGTPQQVAFVVQQGVIPPFCKMLSVRDAQVVQVVLDGILNILKVANDQSDLVCTMIEECGGLDLIEQLQHHENGEIYKLAYDIIDNFFN-DEMEETENQNGMEMRSGVDASDMNALQQNNTGGFNF 1610
            R    KN  +D + MRR R E  VELRKNKR+E L K+RN+P   SLE  + + +   Q   L  I+ N+T+ NP V+L A+QAARKLLSSD+NPPID+LI+SGI+PILV+CL+ D +P++QFEAAWALTNIASGTS QT AVVQ+ AVPLFL+LL S H NVCEQAVWALGNIIGDGP  RDY ISLGVV PLL F+N  +PITFLRNVTWVIVNLCRNKDPPP   T+ E+LPAL  LI + D NILVDTVWALSYLTDGGN+QIQMVI++ +V FLVPLLSH +VKVQTAALRAVGNIVTGTDEQTQ VLN D LSHFP LL H KEKINKEAVWFLSNITAGNQ+QVQAVID  LIP+II+ L KGDF TQKEAAW ISNLTISG   QV ++VQQ VIPPFC +LSV+D+QVVQVVLDG+ NIL +A D++  +  +IEECGGL+ IE LQ HEN +IYKLA++IID +F+ D+++E  +      + G    D  A  Q  T  FNF
Sbjct:   11 RIKSFKNKGRDVETMRRHRNEVTVELRKNKRDEHLLKKRNVPQEESLEDSDVDADFKAQNVTLEAILQNATSDNPVVQLSAVQAARKLLSSDRNPPIDDLIKSGILPILVKCLERDDNPSLQFEAAWALTNIASGTSAQTQAVVQSNAVPLFLRLLHSPHQNVCEQAVWALGNIIGDGPQCRDYVISLGVVKPLLSFINPSIPITFLRNVTWVIVNLCRNKDPPPPMETVQEILPALCVLIYHTDINILVDTVWALSYLTDGGNEQIQMVIDSGVVPFLVPLLSHQEVKVQTAALRAVGNIVTGTDEQTQVVLNCDVLSHFPNLLSHPKEKINKEAVWFLSNITAGNQQQVQAVIDAGLIPMIIHQLAKGDFGTQKEAAWAISNLTISGRKDQVEYLVQQNVIPPFCNLLSVKDSQVVQVVLDGLKNILIMAGDEASTIAEIIEECGGLEKIEVLQQHENEDIYKLAFEIIDQYFSGDDIDEDPSLIPEATQGGTYNFDPTANLQ--TKEFNF 521          
BLAST of Importin subunit alpha vs. UniProt/SwissProt
Match: sp|O00505|IMA4_HUMAN (Importin subunit alpha-4 OS=Homo sapiens OX=9606 GN=KPNA3 PE=1 SV=2)

HSP 1 Score: 669.078 bits (1725), Expect = 0.000e+0
Identity = 334/487 (68.58%), Postives = 394/487 (80.90%), Query Frame = 3
Query:   69 SIMSDRRNMHKNASKDTDEMRRRRVEGNVELRKNKREETLQKRRNLP---SLEADENEIEEPLQMGNLSEIVANSTNPNPTVRLEAIQAARKLLSSDKNPPIDNLIQSGIMPILVECLDNDAHPNIQFEAAWALTNIASGTSEQTNAVVQAGAVPLFLKLLGSTHSNVCEQAVWALGNIIGDGPTLRDYAISLGVVAPLLKFLNADVPITFLRNVTWVIVNLCRNKDPPPSPVTISELLPALRFLIQNIDTNILVDTVWALSYLTDGGNDQIQMVIEADIVRFLVPLLSHNDVKVQTAALRAVGNIVTGTDEQTQYVLNFDALSHFPQLLQHSKEKINKEAVWFLSNITAGNQEQVQAVIDYSLIPLIIYHLDKGDFQTQKEAAWVISNLTISGTPQQVAFVVQQGVIPPFCKMLSVRDAQVVQVVLDGILNILKVANDQSDLVCTMIEECGGLDLIEQLQHHENGEIYKLAYDIIDNFFN-DEMEE 1517
            S+ + R    KN  +D + MRR R E  VELRKNKR+E L K+RN+P   SLE  + + +   Q   L  I+ N+T+ NP V+L A+QAARKLLSSD+NPPID+LI+SGI+PILV+CL+ D +P++QFEAAWALTNIASGTS QT AVVQ+ AVPLFL+LL S H NVCEQAVWALGNIIGDGP  RDY ISLGVV PLL F++  +PITFLRNVTWVIVNLCRNKDPPP   T+ E+LPAL  LI + D NILVDTVWALSYLTDGGN+QIQMVI++ +V FLVPLLSH +VKVQTAALRAVGNIVTGTDEQTQ VLN D LSHFP LL H KEKINKEAVWFLSNITAGNQ+QVQAVID  LIP+II+ L KGDF TQKEAAW ISNLTISG   QV ++VQQ VIPPFC +LSV+D+QVVQVVLDG+ NIL +A D++  +  +IEECGGL+ IE LQ HEN +IYKLA++IID +F+ D+++E
Sbjct:    6 SLENHRIKSFKNKGRDVETMRRHRNEVTVELRKNKRDEHLLKKRNVPQEESLEDSDVDADFKAQNVTLEAILQNATSDNPVVQLSAVQAARKLLSSDRNPPIDDLIKSGILPILVKCLERDDNPSLQFEAAWALTNIASGTSAQTQAVVQSNAVPLFLRLLRSPHQNVCEQAVWALGNIIGDGPQCRDYVISLGVVKPLLSFISPSIPITFLRNVTWVIVNLCRNKDPPPPMETVQEILPALCVLIYHTDINILVDTVWALSYLTDGGNEQIQMVIDSGVVPFLVPLLSHQEVKVQTAALRAVGNIVTGTDEQTQVVLNCDVLSHFPNLLSHPKEKINKEAVWFLSNITAGNQQQVQAVIDAGLIPMIIHQLAKGDFGTQKEAAWAISNLTISGRKDQVEYLVQQNVIPPFCNLLSVKDSQVVQVVLDGLKNILIMAGDEASTIAEIIEECGGLEKIEVLQQHENEDIYKLAFEIIDQYFSGDDIDE 492          
BLAST of Importin subunit alpha vs. UniProt/SwissProt
Match: sp|O00629|IMA3_HUMAN (Importin subunit alpha-3 OS=Homo sapiens OX=9606 GN=KPNA4 PE=1 SV=1)

HSP 1 Score: 669.078 bits (1725), Expect = 0.000e+0
Identity = 334/482 (69.29%), Postives = 400/482 (82.99%), Query Frame = 3
Query:   84 RRNMHKNASKDTDEMRRRRVEGNVELRKNKREETLQKRRNLPSLE-ADENEIEEPLQMGN--LSEIVANSTNPNPTVRLEAIQAARKLLSSDKNPPIDNLIQSGIMPILVECLDNDAHPNIQFEAAWALTNIASGTSEQTNAVVQAGAVPLFLKLLGSTHSNVCEQAVWALGNIIGDGPTLRDYAISLGVVAPLLKFLNADVPITFLRNVTWVIVNLCRNKDPPPSPVTISELLPALRFLIQNIDTNILVDTVWALSYLTDGGNDQIQMVIEADIVRFLVPLLSHNDVKVQTAALRAVGNIVTGTDEQTQYVLNFDALSHFPQLLQHSKEKINKEAVWFLSNITAGNQEQVQAVIDYSLIPLIIYHLDKGDFQTQKEAAWVISNLTISGTPQQVAFVVQQGVIPPFCKMLSVRDAQVVQVVLDGILNILKVANDQSDLVCTMIEECGGLDLIEQLQHHENGEIYKLAYDIIDNFF-NDEMEE 1517
            R    KN  +D + MRR+R E  VELRKNKR+E L KRRN+P  +  ++++I+   ++ N  L  IV N+++ N  ++L A+QAARKLLSSD+NPPID+LI+SGI+PILV CL+ D +P++QFEAAWALTNIASGTSEQT AVVQ+ AVPLFL+LL S H NVCEQAVWALGNIIGDGP  RDY ISLGVV PLL F++  +PITFLRNVTWV+VNLCR+KDPPP   TI E+LPAL  LI + D NILVDTVWALSYLTD GN+QIQMVI++ IV  LVPLLSH +VKVQTAALRAVGNIVTGTDEQTQ VLN DALSHFP LL H KEKINKEAVWFLSNITAGNQ+QVQAVID +L+P+II+ LDKGDF TQKEAAW ISNLTISG   QVA+++QQ VIPPFC +L+V+DAQVVQVVLDG+ NILK+A D+++ +  +IEECGGL+ IEQLQ+HEN +IYKLAY+IID FF +D+++E
Sbjct:   11 RLKNFKNKGRDLETMRRQRNEVVVELRKNKRDEHLLKRRNVPHEDICEDSDIDGDYRVQNTSLEAIVQNASSDNQGIQLSAVQAARKLLSSDRNPPIDDLIKSGILPILVHCLERDDNPSLQFEAAWALTNIASGTSEQTQAVVQSNAVPLFLRLLHSPHQNVCEQAVWALGNIIGDGPQCRDYVISLGVVKPLLSFISPSIPITFLRNVTWVMVNLCRHKDPPPPMETIQEILPALCVLIHHTDVNILVDTVWALSYLTDAGNEQIQMVIDSGIVPHLVPLLSHQEVKVQTAALRAVGNIVTGTDEQTQVVLNCDALSHFPALLTHPKEKINKEAVWFLSNITAGNQQQVQAVIDANLVPMIIHLLDKGDFGTQKEAAWAISNLTISGRKDQVAYLIQQNVIPPFCNLLTVKDAQVVQVVLDGLSNILKMAEDEAETIGNLIEECGGLEKIEQLQNHENEDIYKLAYEIIDQFFSSDDIDE 492          
BLAST of Importin subunit alpha vs. UniProt/SwissProt
Match: sp|Q19969|IMA3_CAEEL (Importin subunit alpha-3 OS=Caenorhabditis elegans OX=6239 GN=ima-3 PE=1 SV=2)

HSP 1 Score: 607.831 bits (1566), Expect = 0.000e+0
Identity = 311/515 (60.39%), Postives = 386/515 (74.95%), Query Frame = 3
Query:   78 SDRRNMHKNASKDTDEMRRRRVEGNVELRKNKREETLQKRRNLPSLEADENEIEE----PLQMGNLSEIVANSTNPNPTVRLEAIQAARKLLSSDKNPPIDNLIQSGIMPILVECLDNDAHPNIQFEAAWALTNIASGTSEQTNAVVQAGAVPLFLKLLGSTHSNVCEQAVWALGNIIGDGPTLRDYAISLGVVAPLLKFLNADVPITFLRNVTWVIVNLCRNKDPPPSPVTISELLPALRFLIQNIDTNILVDTVWALSYLTDGGNDQIQMVIEADIVRFLVPLLSHNDVKVQTAALRAVGNIVTGTDEQTQYVLNFDALSHFPQLLQHSKEKINKEAVWFLSNITAGNQEQVQAVIDYSLIPLIIYHLDKGDFQTQKEAAWVISNLTISGTPQQVAFVVQQGVIPPFCKMLSVRDAQVVQVVLDGILNILKVANDQSDLVCTMIEECGGLDLIEQLQHHENGEIYKLAYDIIDNFFNDEMEETENQNGMEMRSGVDASDMNALQQNNTGGFNF 1610
            S+R+  +KN +K+    + +R E  V +RK+KREE + KRRN+ +   D++E       P     L   VA + + +P  +L A+Q ARK+LS+D+NPPID+LI SGI+P+LV+CL +   PN+QFEAAWALTNIASGTSEQT AVV AGAVPLFL+LL   + NVCEQ+VWALGNIIGDGP  RDY + LG++ PLL+F+N ++PI FLRNVTWVIVNLCR KDP PSP  +  +LPAL  LI + DTNIL+DTVWALSYLTDGGN+ IQMVIEA +V  LVPLL H DVKVQTAALRAVGNIVTGTDEQTQ VL+   L   P LL H KEKINKEAVWF+SNITAGNQ+QVQ V D  ++P+II+ LD+GDF TQKEAAW ISN+TISG P QV  +V+ GV+ PFC MLS  D+Q++QVVLDGI NILK+A + ++ V + IEECGGLD IE LQ+HEN +IYKLA++IIDNFF+ + +ET N  G +  S     D+  +     GG+NF
Sbjct:    3 SNRQAYYKNNAKEQIG-KEKRNEEVVSIRKDKREEAISKRRNINTQIEDDSETSTTPPGPFDANLLRLTVAAAQSSDPAEQLTAVQQARKMLSTDRNPPIDDLIGSGILPVLVQCLSS-TDPNLQFEAAWALTNIASGTSEQTQAVVNAGAVPLFLQLLSCGNLNVCEQSVWALGNIIGDGPHFRDYCLELGILQPLLQFINPEIPIGFLRNVTWVIVNLCRCKDPAPSPAVVRTILPALSLLIHHQDTNILIDTVWALSYLTDGGNEHIQMVIEAQVVTHLVPLLGHVDVKVQTAALRAVGNIVTGTDEQTQLVLDSGVLRFMPGLLAHYKEKINKEAVWFVSNITAGNQQQVQDVFDAGIMPMIIHLLDRGDFPTQKEAAWAISNVTISGRPNQVEQMVKLGVLRPFCAMLSCTDSQIIQVVLDGINNILKMAGEAAEQVTSEIEECGGLDKIENLQNHENEDIYKLAFEIIDNFFSSD-DETGNVEGAQ--SSAFGGDVPPVPDAPNGGWNF 512          
BLAST of Importin subunit alpha vs. TrEMBL
Match: A0A210PVP2 (Importin subunit alpha OS=Mizuhopecten yessoensis OX=6573 GN=KP79_PYT19997 PE=3 SV=1)

HSP 1 Score: 701.819 bits (1810), Expect = 0.000e+0
Identity = 343/509 (67.39%), Postives = 409/509 (80.35%), Query Frame = 3
Query:   84 RRNMHKNASKDTDEMRRRRVEGNVELRKNKREETLQKRRNLPSLEADENEIEEPLQMGNLSEIVANSTNPNPTVRLEAIQAARKLLSSDKNPPIDNLIQSGIMPILVECLDNDAHPNIQFEAAWALTNIASGTSEQTNAVVQAGAVPLFLKLLGSTHSNVCEQAVWALGNIIGDGPTLRDYAISLGVVAPLLKFLNADVPITFLRNVTWVIVNLCRNKDPPPSPVTISELLPALRFLIQNIDTNILVDTVWALSYLTDGGNDQIQMVIEADIVRFLVPLLSHNDVKVQTAALRAVGNIVTGTDEQTQYVLNFDALSHFPQLLQHSKEKINKEAVWFLSNITAGNQEQVQAVIDYSLIPLIIYHLDKGDFQTQKEAAWVISNLTISGTPQQVAFVVQQGVIPPFCKMLSVRDAQVVQVVLDGILNILKVANDQSDLVCTMIEECGGLDLIEQLQHHENGEIYKLAYDIIDNFFNDEMEETENQNGMEMRSGVDASDMNALQQNNTGGFNF 1610
            R ++ KN  KD +EMRRRR E  VELRKNKR+  + KRRN+P+ ++ ++E  E     +L  IVAN+++P PTV+L A+QAARKLLSSD+NPPID+LI SGI+P LV+CL  D +P++QFEAAWALTNIASG+SEQT AVV AGAVP FL+LL S H NVCEQAVWALGNIIGDGP  RDY I LG V PLL F+N ++P+ FLRNV WVIVNLCRNK+PPP   TI E+LPAL  LI + D NILVDTVWALSYLTDGGN+QIQMVI++++V FLVPLLSH DVKVQTAALRAVGNIVTGTD++TQ VLN DALSHFP LL H KEKINKE+VWFLSNITAGNQ+QVQAVID  LIPLII+HL +GDFQT+KEAAW ISNLTISG  +QV++VV+QGVIPPFC +LSV+D QVVQVVLDGI NILK+A D+ + +C ++EECGGLD IE LQ+HEN +IY+LAY+IIDN+F+DE EE                D + L ++ T GF F
Sbjct:   10 RTHLFKNKGKDAEEMRRRRTEVTVELRKNKRDHYVLKRRNVPAQDSTDSEDTEKPTHDSLQAIVANASSPEPTVQLTAVQAARKLLSSDRNPPIDDLISSGILPTLVDCLVKDDNPSLQFEAAWALTNIASGSSEQTQAVVNAGAVPYFLRLLESPHQNVCEQAVWALGNIIGDGPRCRDYVIQLGAVKPLLSFINPNIPLPFLRNVAWVIVNLCRNKEPPPPLDTIQEILPALTQLIHHTDINILVDTVWALSYLTDGGNEQIQMVIDSEVVPFLVPLLSHPDVKVQTAALRAVGNIVTGTDDETQVVLNCDALSHFPALLTHPKEKINKESVWFLSNITAGNQQQVQAVIDAGLIPLIIHHLVRGDFQTKKEAAWAISNLTISGRKEQVSYVVEQGVIPPFCDLLSVKDTQVVQVVLDGINNILKMAADEVESICQVVEECGGLDKIENLQNHENSDIYRLAYEIIDNYFSDETEE----------------DPSVLPESTTQGFQF 502          
BLAST of Importin subunit alpha vs. TrEMBL
Match: T1IVG4 (Importin subunit alpha OS=Strigamia maritima OX=126957 PE=3 SV=1)

HSP 1 Score: 701.819 bits (1810), Expect = 0.000e+0
Identity = 343/484 (70.87%), Postives = 404/484 (83.47%), Query Frame = 3
Query:   69 SIMSDRRNMHKNASKDTDEMRRRRVEGNVELRKNKREETLQKRRNLPSLEA-DENEIEEPLQMGNLSEIVANSTNPNPTVRLEAIQAARKLLSSDKNPPIDNLIQSGIMPILVECLDNDAHPNIQFEAAWALTNIASGTSEQTNAVVQAGAVPLFLKLLGSTHSNVCEQAVWALGNIIGDGPTLRDYAISLGVVAPLLKFLNADVPITFLRNVTWVIVNLCRNKDPPPSPVTISELLPALRFLIQNIDTNILVDTVWALSYLTDGGNDQIQMVIEADIVRFLVPLLSHNDVKVQTAALRAVGNIVTGTDEQTQYVLNFDALSHFPQLLQHSKEKINKEAVWFLSNITAGNQEQVQAVIDYSLIPLIIYHLDKGDFQTQKEAAWVISNLTISGTPQQVAFVVQQGVIPPFCKMLSVRDAQVVQVVLDGILNILKVANDQSDLVCTMIEECGGLDLIEQLQHHENGEIYKLAYDIIDNFFNDEMEE 1517
            +I   R    KN  KD DEMRRRR E  VELRKNKREE+L KRRN+P  ++ DE E ++ L   +L  IV N+++  P+++L A+QAARKLLSSD+NPPID+LIQSGI+PILV CL+   + ++QFEAAWALTNIASGTS+QT AVV AGAVPLFL+LL S H NVCEQAVWALGNIIGDGP LRDY ISLGVV PLL F+N ++PI+FLRNVTWVIVNLCRNKDP P   TI+E+LPAL  LI + D NILVDTVWALSYLTDGGNDQIQMVI+  +V++LVPLLSH +VKVQTAALRAVGNIVTG+DEQTQ VLN +ALSHFP LL H K+KINKE+VWFLSNITAGNQ+QVQAVID +LIPLII+HL +GDFQTQKEAAW ISNLTISG   QVA++VQ+GVIPPFC +L+ +D QV+QVVLDGI NILK+A +Q   +C+MIEECGGLD IE LQ+HEN EIYKL+YDIID +F++E +E
Sbjct:    5 AINKSRIQHFKNKGKDQDEMRRRRNEVTVELRKNKREESLLKRRNVPQTDSTDEEETDKGLNHTSLETIVLNASSNQPSLQLSAVQAARKLLSSDRNPPIDDLIQSGILPILVHCLECHENASLQFEAAWALTNIASGTSQQTQAVVNAGAVPLFLQLLHSPHQNVCEQAVWALGNIIGDGPGLRDYVISLGVVQPLLAFINPEIPISFLRNVTWVIVNLCRNKDPSPPAETINEILPALCMLIHHTDVNILVDTVWALSYLTDGGNDQIQMVIDCGVVQYLVPLLSHKEVKVQTAALRAVGNIVTGSDEQTQVVLNCNALSHFPALLTHQKDKINKESVWFLSNITAGNQQQVQAVIDANLIPLIIHHLGRGDFQTQKEAAWAISNLTISGNKNQVAYLVQEGVIPPFCSLLTCKDVQVIQVVLDGITNILKMAGNQLVAICSMIEECGGLDNIEVLQNHENEEIYKLSYDIIDQYFSEEADE 488          

HSP 2 Score: 69.707 bits (169), Expect = 1.644e-8
Identity = 59/231 (25.54%), Postives = 107/231 (46.32%), Query Frame = 3
Query:  837 ALSYLTDGGNDQIQMVIEADIVRFLVPLL-SHNDVKVQTAALRAVGNIVTGTDEQTQYVLNFDALSHFPQLLQHSKEKINKEAVWFLSNITAGNQEQVQAVIDYSLI-PLIIYHLDKGDFQTQKEAAWVISNLTISGTPQQVAFVVQQGVIPPFCKMLSVRDAQVVQVVLDGILNILKVANDQSDLVCTMIEECGGLDLIEQLQHHENGEIYKLAYDIIDNFFNDEMEETE 1523
            A   L+   N  I  +I++ I+  LV  L  H +  +Q  A  A+ NI +GT +QTQ V+N  A+  F QLL    + + ++AVW L NI          VI   ++ PL+ +   +      +   WVI NL  +  P   A  + + ++P  C ++   D   V +++D +  +  + +  +D +  M+ +CG +  +  L  H+  ++   A   + N      E+T+
Sbjct:   92 ARKLLSSDRNPPIDDLIQSGILPILVHCLECHENASLQFEAAWALTNIASGTSQQTQAVVNAGAVPLFLQLLHSPHQNVCEQAVWALGNIIGDGPGLRDYVISLGVVQPLLAFINPEIPISFLRNVTWVIVNLCRNKDPSPPAETINE-ILPALCMLIHHTD---VNILVDTVWALSYLTDGGNDQI-QMVIDCGVVQYLVPLLSHKEVKVQTAALRAVGNIVTGSDEQTQ 317          
BLAST of Importin subunit alpha vs. TrEMBL
Match: Q6QJF2 (Importin subunit alpha OS=Aplysia californica OX=6500 PE=2 SV=1)

HSP 1 Score: 692.189 bits (1785), Expect = 0.000e+0
Identity = 340/478 (71.13%), Postives = 393/478 (82.22%), Query Frame = 3
Query:   84 RRNMHKNASKDTDEMRRRRVEGNVELRKNKREETLQKRRNLPSLEADENEIEEPLQMGNLSEIVANSTNPNPTVRLEAIQAARKLLSSDKNPPIDNLIQSGIMPILVECLDNDAHPNIQFEAAWALTNIASGTSEQTNAVVQAGAVPLFLKLLGSTHSNVCEQAVWALGNIIGDGPTLRDYAISLGVVAPLLKFLNADVPITFLRNVTWVIVNLCRNKDPPPSPVTISELLPALRFLIQNIDTNILVDTVWALSYLTDGGNDQIQMVIEADIVRFLVPLLSHNDVKVQTAALRAVGNIVTGTDEQTQYVLNFDALSHFPQLLQHSKEKINKEAVWFLSNITAGNQEQVQAVIDYSLIPLIIYHLDKGDFQTQKEAAWVISNLTISGTPQQVAFVVQQGVIPPFCKMLSVRDAQVVQVVLDGILNILKVANDQSDLVCTMIEECGGLDLIEQLQHHENGEIYKLAYDIIDNFFNDEMEE 1517
            R  M KN  KD DEMRRRR E  VELRKNK+EE + KRRN+P+ ++ ++E  E     +L  IVAN+++P P V+L A+QAARKLLSSD+NPPID+LI SGI+PILV CL  D +P++QFEAAWA+TNIASGTS QT AVV AGAVP FL+LL S H NVCEQAVWALGNIIGDGP  R+Y ISLG V  LL F+N ++P+ FLRNV WVIVNLCRNKDPPP   TI E+LPAL  LI + D NILVDTVWALSYLTDGGNDQIQMVI++ +V FLVPLL H DVK+QTAALRAVGNIVTGTDEQTQ VLN +AL HF  LL H KEKINKEAVWFLSNITAGNQ+QVQAVID SLIPLII+HL++GDFQTQKEAAW ISNLTISG  +QVA+VV+ GV+PPFC +LSV+DAQVV VVLDGI NILK+A +  D +C +IEECGGLD IE LQ+HEN EIYKL+Y+IID+FF DE +E
Sbjct:   11 RGLMFKNKGKDADEMRRRRTEVTVELRKNKKEEHMLKRRNVPTQDSTDSEDNEKPTTQSLETIVANASSPEPEVQLGAVQAARKLLSSDRNPPIDDLITSGILPILVNCLSRDDNPSLQFEAAWAITNIASGTSAQTQAVVNAGAVPFFLQLLRSPHQNVCEQAVWALGNIIGDGPECRNYVISLGAVQHLLTFINPNIPLPFLRNVAWVIVNLCRNKDPPPPAETIEEILPALCTLIHHSDVNILVDTVWALSYLTDGGNDQIQMVIDSGVVPFLVPLLCHQDVKLQTAALRAVGNIVTGTDEQTQAVLNCNALQHFSSLLTHPKEKINKEAVWFLSNITAGNQQQVQAVIDASLIPLIIHHLNRGDFQTQKEAAWAISNLTISGKKEQVAYVVEMGVLPPFCNLLSVKDAQVVNVVLDGINNILKMAGEDVDQICQIIEECGGLDKIENLQNHENEEIYKLSYEIIDSFFQDEDQE 488          
BLAST of Importin subunit alpha vs. TrEMBL
Match: V4CR36 (Importin subunit alpha OS=Lottia gigantea OX=225164 GN=LOTGIDRAFT_211744 PE=3 SV=1)

HSP 1 Score: 691.034 bits (1782), Expect = 0.000e+0
Identity = 341/482 (70.75%), Postives = 397/482 (82.37%), Query Frame = 3
Query:   75 MSDRRNMHKNASKDTDEMRRRRVEGNVELRKNKREETLQKRRNLPSLEADENEIEEPLQMGNLSEIVANSTNPNPTVRLEAIQAARKLLSSDKNPPIDNLIQSGIMPILVECLDNDAHPNIQFEAAWALTNIASGTSEQTNAVVQAGAVPLFLKLLGSTHSNVCEQAVWALGNIIGDGPTLRDYAISLGVVAPLLKFLNADVPITFLRNVTWVIVNLCRNKDPPPSPVTISELLPALRFLIQNIDTNILVDTVWALSYLTDGGNDQIQMVIEADIVRFLVPLLSHNDVKVQTAALRAVGNIVTGTDEQTQYVLNFDALSHFPQLLQHSKEKINKEAVWFLSNITAGNQEQVQAVIDYSLIPLIIYHLDKGDFQTQKEAAWVISNLTISGTPQQVAFVVQQGVIPPFCKMLSVRDAQVVQVVLDGILNILKVANDQSDLVCTMIEECGGLDLIEQLQHHENGEIYKLAYDIIDNFFN-DEMEE 1517
            +  R ++ KN  KD DEMRRRR E  VELRK+KREE + KRRN+P+ ++ ++E  E     +L  IVAN+ +P P+V+  A+QAARKLLSSD+NPPID+LI SGI+PILV CL  D   ++QFEAAWALTNIASGTS QT AVVQAGAVPLFL+LL STHSNVCEQAVWALGNIIGDGP  RDY ISLG V PLL F+N  +P+TFLRNV WVIVNLCRNK+PPP   TI E+LPAL +LI + D NILVDTVWALSYLTDGGNDQIQ+VI+A++V  LVPLLSH DVKVQTAALRAVGNIVTG+DEQTQ VL+ DALSHFP LL H KEKINKEAVWFLSN+TAGNQ+QVQAVID +LIPL+I+HL +G+FQTQKEAAW ISNLTISG  +QV FVV  GVIPPFC +LSV+D QVV VVLDGI NILK+A D+ + +  MIEECGGLD +E LQ+HEN +IYKLAY IID++F+ DE EE
Sbjct:    9 LKGRGHLFKNKGKDPDEMRRRRTEVTVELRKSKREEHMLKRRNVPAQDSTDSEDSERTTPQSLQSIVANAASPEPSVQFSAVQAARKLLSSDRNPPIDDLIASGILPILVGCLIKDDFSSLQFEAAWALTNIASGTSAQTKAVVQAGAVPLFLRLLHSTHSNVCEQAVWALGNIIGDGPQCRDYVISLGAVKPLLNFINPKIPLTFLRNVAWVIVNLCRNKEPPPPIRTIEEILPALCYLIHHTDVNILVDTVWALSYLTDGGNDQIQLVIDANVVPLLVPLLSHPDVKVQTAALRAVGNIVTGSDEQTQTVLSCDALSHFPSLLTHPKEKINKEAVWFLSNVTAGNQQQVQAVIDANLIPLVIHHLSRGEFQTQKEAAWAISNLTISGKKEQVMFVVTLGVIPPFCDLLSVKDTQVVNVVLDGINNILKIA-DEPETIAQMIEECGGLDKVEALQNHENEDIYKLAYLIIDHYFSGDEDEE 489          
BLAST of Importin subunit alpha vs. TrEMBL
Match: A0A2C9JNB0 (Importin subunit alpha OS=Biomphalaria glabrata OX=6526 GN=106060993 PE=3 SV=1)

HSP 1 Score: 689.878 bits (1779), Expect = 0.000e+0
Identity = 338/478 (70.71%), Postives = 391/478 (81.80%), Query Frame = 3
Query:   84 RRNMHKNASKDTDEMRRRRVEGNVELRKNKREETLQKRRNLPSLEADENEIEEPLQMGNLSEIVANSTNPNPTVRLEAIQAARKLLSSDKNPPIDNLIQSGIMPILVECLDNDAHPNIQFEAAWALTNIASGTSEQTNAVVQAGAVPLFLKLLGSTHSNVCEQAVWALGNIIGDGPTLRDYAISLGVVAPLLKFLNADVPITFLRNVTWVIVNLCRNKDPPPSPVTISELLPALRFLIQNIDTNILVDTVWALSYLTDGGNDQIQMVIEADIVRFLVPLLSHNDVKVQTAALRAVGNIVTGTDEQTQYVLNFDALSHFPQLLQHSKEKINKEAVWFLSNITAGNQEQVQAVIDYSLIPLIIYHLDKGDFQTQKEAAWVISNLTISGTPQQVAFVVQQGVIPPFCKMLSVRDAQVVQVVLDGILNILKVANDQSDLVCTMIEECGGLDLIEQLQHHENGEIYKLAYDIIDNFFNDEMEE 1517
            R  M KN  KD DEMRRRR E  +ELRKNKREE + KRRN+P+ ++ ++E  E     +L  IVAN+ +  P+V+L A+QAARKLLSSD+NPPID+LI SGI+PILV CL  + +P++QFEAAWALTNIASGTS QT AVV AGAVP FL+LL S H NVCEQAVWALGNIIGDGP  R+Y ISLG V  LL F+N  +P+ FLRNV WVIVNLCRNKDPPP   TI E+LPAL  LI + D NILVDTVWALSYLTDGGN+QIQMVI++ +V FLVPLLSH DVKVQTAALRAVGNIVTGTDEQTQ VLN +AL HFP LL H KEKINKEAVWFLSNITAGNQ QVQAVID  LIPLII+HL++GDFQTQKEAAW ISNLTISG  +QVA+VV+ GV+PPFC +LSV+DAQVV VVLDGI NILK+A D+ + +C +IEECGGLD IE LQ+HEN EIYKL+Y+IID +F D+ +E
Sbjct:   10 RTVMFKNKGKDADEMRRRRTEVTIELRKNKREEHMLKRRNVPTQDSTDSEDNEKPSTQSLETIVANANSSEPSVQLGAVQAARKLLSSDRNPPIDDLIASGILPILVNCLSKEDNPSLQFEAAWALTNIASGTSSQTQAVVNAGAVPYFLQLLRSPHQNVCEQAVWALGNIIGDGPQCRNYVISLGAVQHLLTFINPKIPLPFLRNVAWVIVNLCRNKDPPPPAETIEEILPALCQLIHHSDVNILVDTVWALSYLTDGGNEQIQMVIDSGVVPFLVPLLSHQDVKVQTAALRAVGNIVTGTDEQTQAVLNCNALQHFPSLLTHPKEKINKEAVWFLSNITAGNQHQVQAVIDAGLIPLIIHHLNRGDFQTQKEAAWAISNLTISGKKEQVAYVVEMGVLPPFCNLLSVKDAQVVNVVLDGINNILKMAGDEVEHICQIIEECGGLDKIESLQNHENEEIYKLSYEIIDGYFQDDNDE 487          
BLAST of Importin subunit alpha vs. Ensembl Cavefish
Match: kpna4 (karyopherin subunit alpha 4 [Source:NCBI gene;Acc:103046926])

HSP 1 Score: 672.159 bits (1733), Expect = 0.000e+0
Identity = 333/475 (70.11%), Postives = 392/475 (82.53%), Query Frame = 3
Query:   84 RRNMHKNASKDTDEMRRRRVEGNVELRKNKREETLQKRRNLPSLE-ADENEIEEPLQMGN--LSEIVANSTNPNPTVRLEAIQAARKLLSSDKNPPIDNLIQSGIMPILVECLDNDAHPNIQFEAAWALTNIASGTSEQTNAVVQAGAVPLFLKLLGSTHSNVCEQAVWALGNIIGDGPTLRDYAISLGVVAPLLKFLNADVPITFLRNVTWVIVNLCRNKDPPPSPVTISELLPALRFLIQNIDTNILVDTVWALSYLTDGGNDQIQMVIEADIVRFLVPLLSHNDVKVQTAALRAVGNIVTGTDEQTQYVLNFDALSHFPQLLQHSKEKINKEAVWFLSNITAGNQEQVQAVIDYSLIPLIIYHLDKGDFQTQKEAAWVISNLTISGTPQQVAFVVQQGVIPPFCKMLSVRDAQVVQVVLDGILNILKVANDQSDLVCTMIEECGGLDLIEQLQHHENGEIYKLAYDIIDNFF 1499
            R    KN  +D + MRR+R E  VELRKNKR+E L KRRN+P  +  D+++++   +  N  L  IV N+T+ N  ++L A+QAARKLLSSD+NPPID+LI+SGI+PILV CLD D +P++QFEAAWALTNIASGTSEQT AVVQ+ AVPLFL+LL S H NVCEQAVWALGNIIGDGP  RDY ISLGVV PLL F++  +PITFLRNVTWV+VNLCR+KDPPP   TI E+LPAL  LI + D NILVDTVWALSYLTD GN+QIQMVI++ IV  LVPLLSH +VKVQTAALRAVGNIVTGTDEQTQ VLN DAL HFP LL H KEKINKEAVWFLSNITAGNQ+QVQAVID +L+P+II  LDKGDF TQKEAAW ISNLTISG   QVA+++QQ VIPPFC +L+V+DAQVVQVVLDG+ NILK+A+D+++ +  +IEECGGL+ IEQLQ+HEN +IYKLAY+IID FF
Sbjct:   11 RLKNFKNKGRDLETMRRQRTEVVVELRKNKRDEHLLKRRNVPHEDICDDSDVDGDFRTQNTSLEAIVQNATSDNQGIQLSAVQAARKLLSSDRNPPIDDLIKSGILPILVHCLDRDDNPSLQFEAAWALTNIASGTSEQTQAVVQSNAVPLFLRLLHSPHQNVCEQAVWALGNIIGDGPQCRDYVISLGVVKPLLSFISPSIPITFLRNVTWVMVNLCRHKDPPPPMETIQEILPALCVLIHHTDVNILVDTVWALSYLTDAGNEQIQMVIDSGIVPHLVPLLSHQEVKVQTAALRAVGNIVTGTDEQTQVVLNCDALGHFPALLTHPKEKINKEAVWFLSNITAGNQQQVQAVIDANLVPMIILLLDKGDFGTQKEAAWAISNLTISGRKDQVAYLIQQQVIPPFCNLLTVKDAQVVQVVLDGLSNILKMADDEAETIANLIEECGGLEKIEQLQNHENEDIYKLAYEIIDQFF 485          
BLAST of Importin subunit alpha vs. Ensembl Cavefish
Match: kpna3 (karyopherin subunit alpha 3 [Source:NCBI gene;Acc:103046682])

HSP 1 Score: 662.914 bits (1709), Expect = 0.000e+0
Identity = 331/482 (68.67%), Postives = 390/482 (80.91%), Query Frame = 3
Query:   84 RRNMHKNASKDTDEMRRRRVEGNVELRKNKREETLQKRRNLP---SLEADENEIEEPLQMGNLSEIVANSTNPNPTVRLEAIQAARKLLSSDKNPPIDNLIQSGIMPILVECLDNDAHPNIQFEAAWALTNIASGTSEQTNAVVQAGAVPLFLKLLGSTHSNVCEQAVWALGNIIGDGPTLRDYAISLGVVAPLLKFLNADVPITFLRNVTWVIVNLCRNKDPPPSPVTISELLPALRFLIQNIDTNILVDTVWALSYLTDGGNDQIQMVIEADIVRFLVPLLSHNDVKVQTAALRAVGNIVTGTDEQTQYVLNFDALSHFPQLLQHSKEKINKEAVWFLSNITAGNQEQVQAVIDYSLIPLIIYHLDKGDFQTQKEAAWVISNLTISGTPQQVAFVVQQGVIPPFCKMLSVRDAQVVQVVLDGILNILKVANDQSDLVCTMIEECGGLDLIEQLQHHENGEIYKLAYDIIDNFFN-DEMEE 1517
            R    KN  +D + MRR R E  VELRKNKR+E L K+RN+P   SLE  + + +   Q   L  I+ N+T+ N  V+L A+QAARKLLSSD+NPPID+LI+SGI+PILV+CL+ D +P++QFEAAWALTNIASGTS QT AVV++ AVPLFL+LL S H NVCEQAVWALGNIIGDGP  RDY ISLGVV PLL F+N  +PITFLRNVTWVIVNLCRNKDPPP   T+ E+LPAL  LI + D NILVDTVWALSYLTDGGN+QIQMVI++ +V FLVPLLSH +VKVQTAALRAVGNIVTGTDEQTQ VLN D LSHFP LL H KEKINKEAVWFLSNITAGNQ+QVQAVID  LIP+II+ L KGDF TQKEAAW ISNLTISG   QV ++VQQ VIPPFC +LSV+D+QVVQVVLDG+ NIL +A +++  +  +IEECGGL+ IE LQ HEN +IYKLA++IID +F+ D+++E
Sbjct:   11 RIKSFKNKGRDVETMRRHRNEVTVELRKNKRDEHLLKKRNVPQDESLEDSDVDADFKGQNVTLDAILQNATSDNAVVQLSAVQAARKLLSSDRNPPIDDLIKSGILPILVKCLERDDNPSLQFEAAWALTNIASGTSAQTQAVVKSNAVPLFLRLLHSPHQNVCEQAVWALGNIIGDGPQCRDYVISLGVVKPLLSFINPSIPITFLRNVTWVIVNLCRNKDPPPPMETVQEILPALCVLIYHTDINILVDTVWALSYLTDGGNEQIQMVIDSGVVPFLVPLLSHQEVKVQTAALRAVGNIVTGTDEQTQVVLNCDVLSHFPNLLTHPKEKINKEAVWFLSNITAGNQQQVQAVIDAGLIPMIIHQLAKGDFGTQKEAAWAISNLTISGRKDQVEYLVQQNVIPPFCNLLSVKDSQVVQVVLDGLKNILIMAGEEASTIAEIIEECGGLEKIENLQQHENEDIYKLAFEIIDQYFSGDDIDE 492          
BLAST of Importin subunit alpha vs. Ensembl Cavefish
Match: KPNA3 (importin subunit alpha-4-like [Source:NCBI gene;Acc:103030092])

HSP 1 Score: 662.144 bits (1707), Expect = 0.000e+0
Identity = 330/482 (68.46%), Postives = 392/482 (81.33%), Query Frame = 3
Query:   84 RRNMHKNASKDTDEMRRRRVEGNVELRKNKREETLQKRRNLPSLE-ADENEIEEPLQMGNLS--EIVANSTNPNPTVRLEAIQAARKLLSSDKNPPIDNLIQSGIMPILVECLDNDAHPNIQFEAAWALTNIASGTSEQTNAVVQAGAVPLFLKLLGSTHSNVCEQAVWALGNIIGDGPTLRDYAISLGVVAPLLKFLNADVPITFLRNVTWVIVNLCRNKDPPPSPVTISELLPALRFLIQNIDTNILVDTVWALSYLTDGGNDQIQMVIEADIVRFLVPLLSHNDVKVQTAALRAVGNIVTGTDEQTQYVLNFDALSHFPQLLQHSKEKINKEAVWFLSNITAGNQEQVQAVIDYSLIPLIIYHLDKGDFQTQKEAAWVISNLTISGTPQQVAFVVQQGVIPPFCKMLSVRDAQVVQVVLDGILNILKVANDQSDLVCTMIEECGGLDLIEQLQHHENGEIYKLAYDIIDNFFN-DEMEE 1517
            R    KN  +D + MRR R E +VELRKNKR+E L K+RN+P  E AD+++++  L+  NL+   I+ N+++ N  ++L A+QAARKLLSSD+NPPID+L++SGI+P+LV CLD D HP++QFEAAWALTNIASGTS QT AVVQ+ AVPLFL+LL S H NVCEQAVWALGNIIGDGP  RDY ISLGVV PLL F+   VP++FLRNVTWVIVNLCRNKDPPP   T+ E+LPAL  LI + D NILVDTVWA+SYLTDGGN+QIQMVIE+ +V FLVPLLSH +VKVQTAALRAVGNIVTGTDEQTQ VLN D LSHFP LL H K+KINKEAVWFLSNITAGNQ+QVQAVID  LIPLII+ L KGDF TQKEAAW ISNLTISG  +QV ++VQQGV+ P C +L VRDAQVVQVVLDG+ NIL +A +Q+  V  +IEECGGL+ IE LQ HEN  IYKLA++IID +F+ D+++E
Sbjct:   29 RIKSFKNKGRDAEAMRRHRNEVSVELRKNKRDEHLLKKRNVPQSESADDSDVDNDLKGQNLTLETILQNASSNNNVLQLSAVQAARKLLSSDRNPPIDDLVRSGILPVLVNCLDRDDHPSLQFEAAWALTNIASGTSAQTQAVVQSNAVPLFLRLLHSPHQNVCEQAVWALGNIIGDGPQCRDYVISLGVVKPLLSFICPTVPLSFLRNVTWVIVNLCRNKDPPPPMETVQEILPALSVLIYHTDINILVDTVWAVSYLTDGGNEQIQMVIESGVVPFLVPLLSHQEVKVQTAALRAVGNIVTGTDEQTQAVLNCDVLSHFPLLLTHPKDKINKEAVWFLSNITAGNQQQVQAVIDAGLIPLIIHQLAKGDFGTQKEAAWAISNLTISGKKEQVEYLVQQGVVAPLCDLLVVRDAQVVQVVLDGLKNILLMAGEQASTVSNIIEECGGLEKIENLQQHENEYIYKLAFEIIDQYFSGDDIDE 510          
BLAST of Importin subunit alpha vs. Ensembl Cavefish
Match: kpna3 (karyopherin subunit alpha 3 [Source:NCBI gene;Acc:103046682])

HSP 1 Score: 641.728 bits (1654), Expect = 0.000e+0
Identity = 319/484 (65.91%), Postives = 391/484 (80.79%), Query Frame = 3
Query:   84 RRNMHKNASKDTDEMRRRRVEGNVELRKNKREETLQKRRNLPSLEA-DENEIEEPLQMGNLSEIVA----NSTNPNPTVRLEAIQAARKLLSSDKNPPIDNLIQSGIMPILVECLDNDAHPNIQFEAAWALTNIASGTSEQTNAVVQAGAVPLFLKLLGSTHSNVCEQAVWALGNIIGDGPTLRDYAISLGVVAPLLKFLNADVPITFLRNVTWVIVNLCRNKDPPPSPVTISELLPALRFLIQNIDTNILVDTVWALSYLTDGGNDQIQMVIEADIVRFLVPLLSHNDVKVQTAALRAVGNIVTGTDEQTQYVLNFDALSHFPQLLQHSKEKINKEAVWFLSNITAGNQEQVQAVIDYSLIPLIIYHLDKGDFQTQKEAAWVISNLTISGTPQQVAFVVQQGVIPPFCKMLSVRDAQVVQVVLDGILNILKVANDQSDLVCTMIEECGGLDLIEQLQHHENGEIYKLAYDIIDNFFN-DEMEE 1517
            R    KN  +D + MRR R E  VELRKNKR+E L K+RN+P  E+ ++++++   +   +S++ +    N+T+ N  V+L A+QAARKLLSSD+NPPID+LI+SGI+PILV+CL+ D +P++QFEAAWALTNIASGTS QT AVV++ AVPLFL+LL S H NVCEQAVWALGNIIGDGP  RDY ISLGVV PLL F+N  +PITFLRNVTWVIVNLCRNKDPPP   T+ E+   +   +++++  ILVDTVWALSYLTDGGN+QIQMVI++ +V FLVPLLSH +VKVQTAALRAVGNIVTGTDEQTQ VLN D LSHFP LL H KEKINKEAVWFLSNITAGNQ+QVQAVID  LIP+II+ L KGDF TQKEAAW ISNLTISG   QV ++VQQ VIPPFC +LSV+D+QVVQVVLDG+ NIL +A +++  +  +IEECGGL+ IE LQ HEN +IYKLA++IID +F+ D+++E
Sbjct:   11 RIKSFKNKGRDVETMRRHRNEVTVELRKNKRDEHLLKKRNVPQDESLEDSDVDADFKGVRVSQLFSHSFHNATSDNAVVQLSAVQAARKLLSSDRNPPIDDLIKSGILPILVKCLERDDNPSLQFEAAWALTNIASGTSAQTQAVVKSNAVPLFLRLLHSPHQNVCEQAVWALGNIIGDGPQCRDYVISLGVVKPLLSFINPSIPITFLRNVTWVIVNLCRNKDPPPPMETVQEVR-GVCVCVKDLNCCILVDTVWALSYLTDGGNEQIQMVIDSGVVPFLVPLLSHQEVKVQTAALRAVGNIVTGTDEQTQVVLNCDVLSHFPNLLTHPKEKINKEAVWFLSNITAGNQQQVQAVIDAGLIPMIIHQLAKGDFGTQKEAAWAISNLTISGRKDQVEYLVQQNVIPPFCNLLSVKDSQVVQVVLDGLKNILIMAGEEASTIAEIIEECGGLEKIENLQQHENEDIYKLAFEIIDQYFSGDDIDE 493          
BLAST of Importin subunit alpha vs. Ensembl Cavefish
Match: KPNA3 (importin subunit alpha-4-like [Source:NCBI gene;Acc:103030092])

HSP 1 Score: 630.943 bits (1626), Expect = 0.000e+0
Identity = 314/452 (69.47%), Postives = 372/452 (82.30%), Query Frame = 3
Query:  168 NKREETLQKRRNLPSLE-ADENEIEEPLQMGNLSEIVANSTNPNPTVRLEAIQAARKLLSSDKNPPIDNLIQSGIMPILVECLDNDAHPNIQFEAAWALTNIASGTSEQTNAVVQAGAVPLFLKLLGSTHSNVCEQAVWALGNIIGDGPTLRDYAISLGVVAPLLKFLNADVPITFLRNVTWVIVNLCRNKDPPPSPVTISELLPALRFLIQNIDTNILVDTVWALSYLTDGGNDQIQMVIEADIVRFLVPLLSHNDVKVQTAALRAVGNIVTGTDEQTQYVLNFDALSHFPQLLQHSKEKINKEAVWFLSNITAGNQEQVQAVIDYSLIPLIIYHLDKGDFQTQKEAAWVISNLTISGTPQQVAFVVQQGVIPPFCKMLSVRDAQVVQVVLDGILNILKVANDQSDLVCTMIEECGGLDLIEQLQHHENGEIYKLAYDIIDNFFN-DEMEE 1517
            NKR+E L K+RN+P  E AD+++++  L+       V+N+++ N  ++L A+QAARKLLSSD+NPPID+L++SGI+P+LV CLD D HP++QFEAAWALTNIASGTS QT AVVQ+ AVPLFL+LL S H NVCEQAVWALGNIIGDGP  RDY ISLGVV PLL F+   VP++FLRNVTWVIVNLCRNKDPPP   T+ E+LPAL  LI + D NILVDTVWA+SYLTDGGN+QIQMVIE+ +V FLVPLLSH +VKVQTAALRAVGNIVTGTDEQTQ VLN D LSHFP LL H K+KINKEAVWFLSNITAGNQ+QVQAVID  LIPLII+ L KGDF TQKEAAW ISNLTISG  +QV ++VQQGV+ P C +L VRDAQVVQVVLDG+ NIL +A +Q+  V  +IEECGGL+ IE LQ HEN  IYKLA++IID +F+ D+++E
Sbjct:   30 NKRDEHLLKKRNVPQSESADDSDVDNDLKG------VSNASSNNNVLQLSAVQAARKLLSSDRNPPIDDLVRSGILPVLVNCLDRDDHPSLQFEAAWALTNIASGTSAQTQAVVQSNAVPLFLRLLHSPHQNVCEQAVWALGNIIGDGPQCRDYVISLGVVKPLLSFICPTVPLSFLRNVTWVIVNLCRNKDPPPPMETVQEILPALSVLIYHTDINILVDTVWAVSYLTDGGNEQIQMVIESGVVPFLVPLLSHQEVKVQTAALRAVGNIVTGTDEQTQAVLNCDVLSHFPLLLTHPKDKINKEAVWFLSNITAGNQQQVQAVIDAGLIPLIIHQLAKGDFGTQKEAAWAISNLTISGKKEQVEYLVQQGVVAPLCDLLVVRDAQVVQVVLDGLKNILLMAGEQASTVSNIIEECGGLEKIENLQQHENEYIYKLAFEIIDQYFSGDDIDE 475          
BLAST of Importin subunit alpha vs. Ensembl Sea Lamprey
Match: kpna4 (karyopherin alpha 4 (importin alpha 3) [Source:ZFIN;Acc:ZDB-GENE-030131-5584])

HSP 1 Score: 664.455 bits (1713), Expect = 0.000e+0
Identity = 333/484 (68.80%), Postives = 395/484 (81.61%), Query Frame = 3
Query:   84 RRNMHKNASKDTDEMRRRRVEGNVELRKNKREETLQKRRNLPSLEA-DENEIEEPLQMGN--LSEIVANSTNPNPTVRLEAIQAARKLLSSDKNPPIDNLIQSGIMPILVECLDNDAHPNIQFEAAWALTNIASGTSEQTNAVVQAGAVPLFLKLLGSTHSNVCEQAVWALGNII--GDGPTLRDYAISLGVVAPLLKFLNADVPITFLRNVTWVIVNLCRNKDPPPSPVTISELLPALRFLIQNIDTNILVDTVWALSYLTDGGNDQIQMVIEADIVRFLVPLLSHNDVKVQTAALRAVGNIVTGTDEQTQYVLNFDALSHFPQLLQHSKEKINKEAVWFLSNITAGNQEQVQAVIDYSLIPLIIYHLDKGDFQTQKEAAWVISNLTISGTPQQVAFVVQQGVIPPFCKMLSVRDAQVVQVVLDGILNILKVANDQSDLVCTMIEECGGLDLIEQLQHHENGEIYKLAYDIIDNFFN-DEMEE 1517
            R    KN  +D + MRR+R E  +ELRKNKR+E L KRRN+P  E  DE + +   ++ N  L  IV N+ + NP V+L A+QAARKLLSSD+NPPID+LI SGI+PILV+CL+ + +P++QFEAAWALTNIASGTS QT AVV++ AVPLFLKLL S H NVCEQAVWALGNII  GDGP  RDY ISLGVV PLL F+N  +PITFLRNVTWVIVNLCRNKDPPP   TI E+LPAL  LI + D NILVDTVWALSYLTDGGN+QIQMVI++ +V +LVPLLSH +VKVQTAALRAVGNIVTGTDEQTQ VLN DALSHFP LL H+KEKINKEAVWFLSNITAGNQ+QVQAVID  LIP+II+HL KGDF TQKEAAW ISNLTISG   QV ++V++ VIPPFC +L+V+D QVVQVVLDG+ NILK+A ++ + + ++IEECGGL+ IE LQ HEN +IYKLAY+IID +F+ D+++E
Sbjct:   12 RIKSFKNKGRDAETMRRQRNEVTIELRKNKRDEHLLKRRNVPHEEILDELDFDGDFRLQNASLEAIVQNAASDNPNVQLSAVQAARKLLSSDRNPPIDDLINSGILPILVQCLEREDNPSLQFEAAWALTNIASGTSAQTQAVVKSNAVPLFLKLLHSPHQNVCEQAVWALGNIIAAGDGPQCRDYVISLGVVKPLLAFINPAIPITFLRNVTWVIVNLCRNKDPPPPMETIQEILPALCVLIHHTDINILVDTVWALSYLTDGGNEQIQMVIDSGVVPYLVPLLSHQEVKVQTAALRAVGNIVTGTDEQTQVVLNCDALSHFPALLTHAKEKINKEAVWFLSNITAGNQQQVQAVIDAGLIPMIIHHLAKGDFGTQKEAAWAISNLTISGRKDQVEYLVRENVIPPFCALLAVKDPQVVQVVLDGLNNILKMAGEEVETIASVIEECGGLEKIEALQQHENEDIYKLAYEIIDQYFSADDIDE 495          
BLAST of Importin subunit alpha vs. Ensembl Sea Lamprey
Match: kpna7 (karyopherin alpha 7 (importin alpha 8) [Source:ZFIN;Acc:ZDB-GENE-040426-2023])

HSP 1 Score: 442.965 bits (1138), Expect = 6.551e-148
Identity = 228/481 (47.40%), Postives = 318/481 (66.11%), Query Frame = 3
Query:  126 MRRRRVEGNVELRKNKREETLQKRRNLPSLEADE--NEIEEPLQMG------NLSEIVANSTNPNPTVRLEAIQAARKLLSSDKNPPIDNLIQSGIMPILVECLDNDAHPNIQFEAAWALTNIASGTSEQTNAVVQAGAVPLFLKLLGSTHSNVCEQAVWALGNIIGDGPTLRDYAISLGVVAPLLKFLN----ADVPITFLRNVTWVIVNLCRNKDPPPSPVTISELLPALRFLIQNIDTNILVDTVWALSYLTDGGNDQIQMVIEADIVRFLVPLLSHNDVKVQTAALRAVGNIVTGTDEQTQYVLNFDALSHFPQLLQHSKEKINKEAVWFLSNITAGNQEQVQAVIDYSLIPLIIYHLDKGDFQTQKEAAWVISNLTISGTPQQVAFVVQQGVIPPFCKMLSVRDAQVVQVVLDGILNILKVAND--QSDLVCTMIEECGGLDLIEQLQHHENGEIYKLAYDIIDNFFNDEMEETEN 1526
            +R+ R +  +ELRK ++++ + KRRN+ +++ DE  + ++E  Q G      +L EIV   ++    V+L++ Q ARKLLS +++PP++ +I +G++P  V+ L ++    IQFEAAWALTNIASGTSEQT AVV  GAVP F+ LL S H+++ EQAVWALGNI GDGP LRD  I  G V PLL  +     + + +++LRN+TW I NLCRNK PPP    +  LLPAL  L+ + D  +  D  WALSYL+DG ND+I+MV+ A +V  L  LL+  ++ V T ALR VGNIVTGTD+QTQ V+N   L  F  LL+H +  + KEA W LSNITAG+ EQ+ AVI   LIP ++  L KG+F+ Q+EA W ++NLT  GT   + +VVQ G + P   +L V+D+  V ++LD I NI +  +   Q+D +C M+EE GGLD IE LQ HEN  +YK A +IID +F+++  E EN
Sbjct:    1 LRQHRKDLCLELRKARKDDQILKRRNVAAMD-DEPTSPLQEKQQNGQKAQQMSLEEIVRGVSSNESDVQLQSTQGARKLLSRERHPPLNEIISAGLIPRFVQFLGHEDCSQIQFEAAWALTNIASGTSEQTKAVVDGGAVPAFVALLSSPHAHISEQAVWALGNIAGDGPVLRDLVIKYGAVEPLLALMAMPDLSMLSVSYLRNLTWTISNLCRNKKPPPPEEAVLMLLPALVRLLHHEDREVQTDATWALSYLSDGPNDRIEMVVAAGVVPRLAQLLASPELTVLTPALRTVGNIVTGTDQQTQAVINTGVLPVFQNLLRHQRSNVQKEAAWALSNITAGHAEQINAVITAGLIPPLVEVLHKGEFKAQREAVWAVTNLTSGGTVDHIVYVVQVGAMEPLLSLLEVKDSSTVLIILDAITNIFQAGDKVGQTDKLCMMVEELGGLDKIEHLQSHENEAVYKAALNIIDKYFSEDDSEAEN 480          
BLAST of Importin subunit alpha vs. Ensembl Sea Lamprey
Match: ENSPMAT00000005568.1 (pep scaffold:Pmarinus_7.0:GL477092:38612:43101:1 gene:ENSPMAG00000005012.1 transcript:ENSPMAT00000005568.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 322.398 bits (825), Expect = 1.836e-102
Identity = 187/434 (43.09%), Postives = 251/434 (57.83%), Query Frame = 3
Query:  330 RKLLSSDKNPPIDNLIQSGIMPILVECLDNDAHPNIQFEAAWALTNIASGTSEQTNAVVQAGAVPLFLKLLGSTHSNVCEQAVWALGNIIGDGPTLRDYAISLGVVAPLLKFL---NAD-VPITFLRNVTWVIVNLCRNKDPPPSPVTISELLPALRFLIQNIDTNILVDTVWALSYLTDGGNDQIQMVIEADIVRFLVPLLSHNDVKVQTAALRAVGNIVTGTDEQTQYVLNFDALSHFPQLLQHSKEKINKEAVWFLSNITAGNQEQVQAVIDYSLIPLIIYHLDKGDFQTQKEAAWVISNLTISGTPQQVAFVVQQGVIPPFCKMLSVRDAQVVQVVLDGILNILKVANDQSDLVCTMIEECGGLDLIEQLQHHENGEIYKLAYDIIDNFFNDEMEETENQNGMEMRSGVDASDMNALQQ---NNTGGFNF 1610
            RK+LS +K+PP +++I +G++P  V CLD D  P +QFEAAWALTNIASGT EQT  VV AGAVP  ++L+ S HS++ EQAVWALGNI GDG   RD  ++ G V PL+  L   N D   +  LRN+TW + NLCRNK+P PS  T+  LLP +  L+ + D  I  D  WALSYLTDG N++I +V    +   LV LL  +   V T  LRA+GN+VTGTDEQTQ VL   AL  FP LL+H K  I KEA W +SN+ AG  +Q++ +I   L+P +I+ LDK          WV   +T    P    FV QQ  +  + K L  R  +   +V  G     K+   ++  +  M+EE  GL+ +E LQ HEN  IYK A  ++D +F+ E      ++G E+        +    Q    + GGF F
Sbjct:    1 RKMLSREKHPPFNDIIAAGLVPEFVACLDRDDCPLLQFEAAWALTNIASGTGEQTAIVVAAGAVPALVRLVSSPHSHISEQAVWALGNIAGDGAEHRDLVVNSGAVGPLVALLENCNIDEFHVGLLRNLTWTLSNLCRNKNPAPSVTTVLMLLPTMVRLLHHADHEIEADAAWALSYLTDGTNERIHLVQAQGVTPRLVQLLGCDVPAVVTPCLRAIGNMVTGTDEQTQVVLKAGALDMFPMLLRHPKSNIQKEATWAVSNVAAGPIDQIEQIIAAGLVPHLIHVLDKLGQSQYLAPTWVCPIITSDALP-SFRFVKQQ--LDTYFKNLLARKDRTPVLVRCGAKAAEKIGEVEN--MTLMVEESEGLENLEMLQMHENETIYKTALALLDKYFSTE------EDGKELVGPTVTGSLYMFTQPSNEHDGGFGF 423          
BLAST of Importin subunit alpha vs. Ensembl Sea Lamprey
Match: kpna6 (karyopherin alpha 6 (importin alpha 7) [Source:ZFIN;Acc:ZDB-GENE-130530-626])

HSP 1 Score: 176.022 bits (445), Expect = 4.821e-51
Identity = 89/173 (51.45%), Postives = 118/173 (68.21%), Query Frame = 3
Query:  921 LSHNDVKVQTAALRAVGNIVTGTDEQTQYVLNFDALSHFPQLLQHSKEKINKEAVWFLSNITAGNQEQVQAVIDYSLIPLIIYHLDKGDFQTQKEAAWVISNLTISGTPQQVAFVVQQGVIPPFCKMLSVRDAQVVQVVLDGILNILKVANDQS-------DLVCTMIEECGG 1418
            L H DVKV + ALRAVGNIVTG D QTQ +LN  AL     LL + KE I KEA W +SNITAG++ Q+QAVID ++ P++I  L K +F+T+KEAAW I+N T  GTP+Q+ F+V+QG I P C +L+V DA++VQV L+G+ NILK+   ++       +  C  IEE  G
Sbjct:   17 LRHTDVKVVSPALRAVGNIVTGDDMQTQVILNCSALPCLLHLLSNPKESIKKEACWTISNITAGSRAQIQAVIDANIFPVLIEILQKAEFRTRKEAAWAITNATSGGTPEQIRFLVEQGCIKPLCDLLTVMDAKIVQVALNGLENILKLGEQEARQDNLGINPYCATIEEAYG 189          

HSP 2 Score: 51.6026 bits (122), Expect = 1.115e-7
Identity = 38/121 (31.40%), Postives = 59/121 (48.76%), Query Frame = 3
Query:  774 LPALRFLIQNIDTNILVDTVWALSYLTDGGNDQIQMVIEADIVRFLVPLLSHNDVKVQTAALRAVGNIVT-GTDEQTQYVLNFDALSHFPQLLQHSKEKINKEAVWFLSNITA-GNQEQVQ 1130
            LP L  L+ N   +I  +  W +S +T G   QIQ VI+A+I   L+ +L   + + +  A  A+ N  + GT EQ ++++    +     LL     KI + A+  L NI   G QE  Q
Sbjct:   52 LPCLLHLLSNPKESIKKEACWTISNITAGSRAQIQAVIDANIFPVLIEILQKAEFRTRKEAAWAITNATSGGTPEQIRFLVEQGCIKPLCDLLTVMDAKIVQVALNGLENILKLGEQEARQ 172          
BLAST of Importin subunit alpha vs. Ensembl Sea Lamprey
Match: ENSPMAT00000008519.1 (pep scaffold:Pmarinus_7.0:GL480915:29739:34392:1 gene:ENSPMAG00000007713.1 transcript:ENSPMAT00000008519.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 111.694 bits (278), Expect = 2.095e-28
Identity = 84/189 (44.44%), Postives = 112/189 (59.26%), Query Frame = 3
Query:   48 VSINIGSSIMSDRRNM--HKNASKDTDEMRRRRVEGNVELRKNKREETLQKRRNLPSLEAD---ENEIEEPLQM----GNLS----EIVANSTNPNPTVRLEAIQAARKLLSSDKNPPIDNLIQS-GIMPILVECLDNDAHPNIQFEAAWALTNIASGTSEQTNAVVQAGAVPLFLKLLGSTHSNVCEQ 572
            VS +I +S   +   M  +KN + +  EMRRRR E  ++LRK KRE+ L KRRN+     D   +N I++P       G  S    E++    + +P  +L A Q  RKLLS + NPPID +I S G++P  VE L    +  +QFEAAWALTNIASGTS QT  V+ AGAVP+F+ LL S   +V EQ
Sbjct:    4 VSTDIMASPAKENYRMRSYKNKALNPQEMRRRREEEGIQLRKQKREQQLFKRRNVDIPNEDVSMDNGIQDPSVTTTIPGEFSVITIEMLQMIFSDDPEHQLAATQKFRKLLSKEPNPPIDEVIVSPGVVPRFVEFLKRRENCTLQFEAAWALTNIASGTSTQTRVVITAGAVPIFITLLSSDFEDVQEQ 192          
BLAST of Importin subunit alpha vs. Ensembl Yeast
Match: SRP1 (Karyopherin alpha homolog; forms a dimer with karyopherin beta Kap95p to mediate import of nuclear proteins, binds the nuclear localization signal of the substrate during import; involved in cotranslational protein degradation; binds ribosome-bound nascent polypeptides; Srp1p and Sts1p couple proteasomes to nascent polypeptides emerging from the ribosome for cotranslational degradation [Source:SGD;Acc:S000005133])

HSP 1 Score: 391.734 bits (1005), Expect = 9.908e-128
Identity = 222/502 (44.22%), Postives = 299/502 (59.56%), Query Frame = 3
Query:   84 RRNMHKNASK-DTDEMRRRRVEGNVELRKNKREETLQKRRNL--PSLEADENEIEEP-----------LQMGNLSEIVANSTNPNPTVRLEAIQAARKLLSSDKNPPIDNLIQSGIMPILVECLDNDAHPNIQFEAAWALTNIASGTSEQTNAVVQAGAVPLFLKLLGSTHSNVCEQAVWALGNIIGDGPTLRDYAISLGVVAPLLKFLNADVPITFLRNVTWVIVNLCRNKDPPPSPVTISELLPALRFLIQNIDTNILVDTVWALSYLTDGGNDQIQMVIEADIVRFLVPLLSHNDVKVQTAALRAVGNIVTGTDEQTQYVLNFDALSHFPQLLQHSKEKINKEAVWFLSNITAGNQEQVQAVIDYSLIPLIIYHLDKGDFQTQKEAAWVISNLTISG--TPQQVAFVVQQGVIPPFCKMLSVRDAQVVQVVLDGILNILKVA-----------NDQSDLVCTMIEECGGLDLIEQLQHHENGEIYKLAYDIIDNFFNDE 1508
            RR   KN  +   DE+RRRR    VELRK KR+E L KRRN   P+  AD +E +E            LQ   L ++     + +   +L A    R++LS +  PPID +IQ+G++P LVE +  +    +Q EAAWALTNIASGTS QT  VV A AVPLF++LL +    V EQA+WALGN+ GD    RDY +    + P+L   N++ P + +R  TW + NLCR K P P    +S+ LP L  LI ++DT  LVD  WA+SYL+DG  + IQ VI+  I + LV LLSH    VQT ALRAVGNIVTG D QTQ V+N   L     LL   KE I KEA W +SNITAGN EQ+QAVID +LIP ++  L+  +++T+KEA W ISN +  G   P  + ++V QG I P C +L + D ++++V LD + NILK+            N+ +D     IE+ GG++ I   Q +EN +IY+ AY II+ +F +E
Sbjct:   17 RRTNFKNKGRFSADELRRRRDTQQVELRKAKRDEALAKRRNFIPPTDGADSDEEDESSVSADQQFYSQLQQ-ELPQMTQQLNSDDMQEQLSATVKFRQILSREHRPPIDVVIQAGVVPRLVEFMRENQPEMLQLEAAWALTNIASGTSAQTKVVVDADAVPLFIQLLYTGSVEVKEQAIWALGNVAGDSTDYRDYVLQCNAMEPILGLFNSNKP-SLIRTATWTLSNLCRGKKPQPDWSVVSQALPTLAKLIYSMDTETLVDACWAISYLSDGPQEAIQAVIDVRIPKRLVELLSHESTLVQTPALRAVGNIVTGNDLQTQVVINAGVLPALRLLLSSPKENIKKEACWTISNITAGNTEQIQAVIDANLIPPLVKLLEVAEYKTKKEACWAISNASSGGLQRPDIIRYLVSQGCIKPLCDLLEIADNRIIEVTLDALENILKMGEADKEARGLNINENADF----IEKAGGMEKIFNCQQNENDKIYEKAYKIIETYFGEE 512          
BLAST of Importin subunit alpha vs. Ensembl Nematostella
Match: EDO31940 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SWI7])

HSP 1 Score: 494.582 bits (1272), Expect = 4.113e-169
Identity = 249/369 (67.48%), Postives = 291/369 (78.86%), Query Frame = 3
Query:   84 RRNMHKNASKDTDEMRRRRVEGNVELRKNKREETLQKRRNLPSLEADENEIEEPLQMGNLSEIVANSTNPNPTVRLEAIQAARKLLSSDKNPPIDNLIQSGIMPILVECLDNDAHPNIQFEAAWALTNIASGTSEQTNAVVQAGAVPLFLKLLGSTHSNVCEQAVWALGNIIGDGPTLRDYAISLGVVAPLLKFLNADVPITFLRNVTWVIVNLCRNKDPPPSPVTISELLPALRFLIQNIDTNILVDTVWALSYLTDGGNDQIQMVIEADIVRFLVPLLSHNDVKVQTAALRAVGNIVTGTDEQTQYVLNFDALSHFPQLLQHSKEKINKEAVWFLSNITAGNQEQVQAVIDYSLIPLIIYHLDKGDF 1190
            R   +KN  KD   +R+RR E  VELRK KRE+ +QKRRN+P    DE +  E  Q  +L+ IV  + + +P+V+L A+QAARKLLS DKNPPID+LI+SGI+PILV+CL  + + ++QFEAAWALTNIASGTSEQT AVV AGAVP FLKLL S   +VCEQAVWALGNI+GDGP LRD+ I  GVV PLLKF+N  VPITFLRNVTWV+VNLCRNK+PPP   TI E+LPAL  LI + D +ILVDTVWALSYLTDGG+ QIQ+VIE+ +V++LVPLLSH ++K+QTAALRAVGNIVTGTDEQTQ VLN  ALSHF  LL H KEKI KEAVWFLSNITAGNQ QVQ VID  LIPLII  L+   F
Sbjct:    9 RLRYYKNKDKDVTALRQRRNEVTVELRKAKREDCMQKRRNVPLDLPDEKD--EKFQRKDLNAIVMEAGSDDPSVQLGAVQAARKLLSKDKNPPIDDLIKSGILPILVQCLQREDNHSLQFEAAWALTNIASGTSEQTQAVVNAGAVPFFLKLLNSPRQHVCEQAVWALGNIVGDGPVLRDFVIGYGVVKPLLKFVNPGVPITFLRNVTWVLVNLCRNKEPPPPIDTIREVLPALALLIHHQDLDILVDTVWALSYLTDGGSHQIQLVIESGVVQYLVPLLSHQEIKLQTAALRAVGNIVTGTDEQTQVVLNHGALSHFTGLLTHHKEKIKKEAVWFLSNITAGNQSQVQEVIDAGLIPLIIQTLETVMF 375          
BLAST of Importin subunit alpha vs. Ensembl Nematostella
Match: EDO29161 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7T4F4])

HSP 1 Score: 491.115 bits (1263), Expect = 2.644e-168
Identity = 241/375 (64.27%), Postives = 291/375 (77.60%), Query Frame = 3
Query:  378 QSGIMPILVECLDNDAHPNIQFEAAWALTNIASGTSEQTNAVVQAGAVPLFLKLLGSTHSNVCEQAVWALGNIIGDGPTLRDYAISLGVVAPLLKFLNADVPITFLRNVTWVIVNLCRNKDPPPSPVTISELLPALRFLIQNIDTNILVDTVWALSYLTDGGNDQIQMVIEADIVRFLVPLLSHNDVKVQTAALRAVGNIVTGTDEQTQYVLNFDALSHFPQLLQHSKEKINKEAVWFLSNITAGNQEQVQAVIDYSLIPLIIYHLDKGDFQTQKEAAWVISNLTISGTPQQVAFVVQQGVIPPFCKMLSVRDAQVVQVVLDGILNILKVANDQSDLVCTMIEECGGLDLIEQLQHHENGEIYKLAYDIIDNFFN 1502
            +SGI+PILV+CL  + + ++QFEAAWALTNIASGTSEQT AVV AGAVP FLKLL S   +VCEQAVWALGNI+GDGP LRD+ I  GVV PLLKF+N  VP    +   W I N+  +       + + ++LPAL  LI + D +ILVDTVWALSYLTDGG+ QIQ+VIE+ +V++LVPLLSH ++K+QTAALRAVGNIVTGTDEQTQ VLN  ALSHF  LL H KEKI KEAVWFLSNITAGNQ QVQ VID  LIPLII  L+ G+FQTQKEAAW ISN+T+SG  +QVA +V    +   CK+L VRD QVVQ+VLDG+ NILK+A D++ ++ T IEE GGLD IE LQHH+N EIYKLA+++ID +F+
Sbjct:    1 RSGILPILVQCLQREDNHSLQFEAAWALTNIASGTSEQTQAVVNAGAVPFFLKLLNSPRQHVCEQAVWALGNIVGDGPVLRDFVIGYGVVKPLLKFVNPGVPFQTQKEAAWAISNMTVSGRREQPLLLLFQVLPALALLIHHQDLDILVDTVWALSYLTDGGSHQIQLVIESGVVQYLVPLLSHQEIKLQTAALRAVGNIVTGTDEQTQVVLNHGALSHFTGLLTHHKEKIKKEAVWFLSNITAGNQSQVQEVIDAGLIPLIIQTLETGEFQTQKEAAWAISNMTVSGRREQVAVLVHCNAVEHLCKLLDVRDTQVVQIVLDGLNNILKMAGDKATVIATAIEEAGGLDKIELLQHHQNEEIYKLAFEMIDRYFS 375          

HSP 2 Score: 63.5438 bits (153), Expect = 1.385e-10
Identity = 58/232 (25.00%), Postives = 99/232 (42.67%), Query Frame = 3
Query:  366 DNLIQSGIMPILVECLDNDAHPNIQFEAAWALTNIASGTSEQTNAVVQAGAVPLFLKLLGSTHSNVCEQAVWALGNIIGDGPTLRDYAISLGVV---APLLKFLNADVPITFLRNVTWVIVNLCRNKDPPPSPVTISELLPALRFLIQNIDTNILVDTVWALSYLTDGGNDQIQMVIEADIVRFLVPLLSHNDVKVQTAALRAVGNI-VTGTDEQTQYVLNFDALSHFPQLL 1049
            D +I  G++  L++ ++       Q EAAWA++N+      +   ++    +P    L+     ++    VWAL  +   G       I  GVV    PLL      +    LR V     N+    D     V     L     L+ +    I  + VW LS +T G   Q+Q VI+A ++  ++  L   + + Q  A  A+ N+ V+G  EQ   +++ +A+ H  +LL
Sbjct:   82 DFVIGYGVVKPLLKFVNPGVPFQTQKEAAWAISNMTVSGRREQPLLLLFQVLPALALLIHHQDLDILVDTVWALSYLTDGGSHQIQLVIESGVVQYLVPLLSHQEIKLQTAALRAVG----NIVTGTDEQTQVVLNHGALSHFTGLLTHHKEKIKKEAVWFLSNITAGNQSQVQEVIDAGLIPLIIQTLETGEFQTQKEAAWAISNMTVSGRREQVAVLVHCNAVEHLCKLL 309          
BLAST of Importin subunit alpha vs. Ensembl Nematostella
Match: EDO30648 (Importin subunit alpha [Source:UniProtKB/TrEMBL;Acc:A7T055])

HSP 1 Score: 463.381 bits (1191), Expect = 3.318e-155
Identity = 236/490 (48.16%), Postives = 329/490 (67.14%), Query Frame = 3
Query:   84 RRNMHKNASKDTDEMRRRRVEGNVELRKNKREETLQKRRNLPS------LEADENEIEEPLQMGNLSEIVANSTNPNPTVRLEAIQAARKLLSSDKNPPIDNLIQSGIMPILVECLDNDAHPNIQFEAAWALTNIASGTSEQTNAVVQAGAVPLFLKLLGSTHSNVCEQAVWALGNIIGDGPTLRDYAISLGVVAPLLKFLNADVPITFLRNVTWVIVNLCRNKDPPPSPVTISELLPALRFLIQNIDTNILVDTVWALSYLTDGGNDQIQMVIEADIVRFLVPLLSHNDVKVQTAALRAVGNIVTGTDEQTQYVLNFDALSHFPQLLQHSKEKINKEAVWFLSNITAGNQEQVQAVIDYSLIPLIIYHLDKGDFQTQKEAAWVISNLTISGTPQQVAFVVQQGVIPPFCKMLSVRDAQVVQVVLDGILNILKVAND---QSDLVCTMIEECGGLDLIEQLQHHENGEIYKLAYDIIDNFFNDEMEETEN 1526
            R    KN  KD+ EMRRRR E +V+LRK+KR+E + KRRN+        L+   N+   P+Q+  L  +V N  + +  +   ++Q+ RK+LS +K+PPID++I +G++P+LV+ LD    P +QFEAAWALTNIASGTSEQT AV + GAVP+F+KLL S H NV EQAVWALGNI GDGP +R+  I+ G + PLL  +     I FLRNVTW + NLCRNK+PPP    + ++LPA+  LI + D  +L DT WALSYLTDG N++IQ+V+++ +V  LV LL + +V V T ALRA+GNIVTG D+QTQ V++  AL +F  LL H K  I KEA W +SN+TAG  +Q+QAV+D  L+PLI+  L +GDF+ +KEA WVI+N      P QV +++   VIPP C+ L ++D + +Q++LDG+ ++L  A+      D     IEE  G+D +E+LQ + N +IY  A  +I+ +F+DE  E EN
Sbjct:    7 RIQAFKNKGKDSSEMRRRRNEVSVQLRKSKRDENVLKRRNITDVDSTSPLKEHNNQHSVPIQILPLPVVVGNLQSGDDNLMFTSVQSVRKMLSKEKSPPIDDVINAGLIPMLVKLLDRFDLPLLQFEAAWALTNIASGTSEQTKAVQEGGAVPMFVKLLSSVHDNVAEQAVWALGNIAGDGPLMRNTVIACGALGPLLALIKPSTSIQFLRNVTWTLSNLCRNKNPPPDVTAVQQVLPAIARLILSDDKEVLADTCWALSYLTDGVNERIQLVLDSGVVPKLVELLGYPEVNVLTPALRAIGNIVTGRDDQTQAVIDTGALFYFRALLTHKKSNIIKEAAWAISNVTAGTAQQIQAVMDSGLVPLIVDILRRGDFKARKEAIWVITNYCSGANPDQVKYLLHCDVIPPLCEQLKIQDQKDIQILLDGLKSLLASASKIEGMLDDTLDKIEESEGIDHLEKLQENGNKQIYLKAKGLIERYFSDENIEEEN 496          
BLAST of Importin subunit alpha vs. Ensembl Nematostella
Match: EDO38337 (Importin subunit alpha [Source:UniProtKB/TrEMBL;Acc:A7SD78])

HSP 1 Score: 422.935 bits (1086), Expect = 1.892e-139
Identity = 233/492 (47.36%), Postives = 317/492 (64.43%), Query Frame = 3
Query:   84 RRNMHKNASKDTDEMRRRRVEGNVELRKNKREETLQKRRNL--PSLEADENEIEEPLQMGNLSE------IVANSTNPNPTVRLEAIQAARKLLSSDKNPPIDNLIQSGIMPILVECLDNDAHPNIQFEAAWALTNIASGTSEQTNAVVQAGAVPLFLKLLGSTHSNVCEQAVWALGNIIGDGPTLRDYAISLGVVAPLLKFLNADVPITFLRNVTWVIVNLCRNKDPPPSPVTISELLPALRFLIQNIDTNILVDTVWALSYLTDGGNDQIQMVIEADIVRFLVPLLSHNDVKVQTAALRAVGNIVTGTDEQTQYVLNFDALSHFPQLLQHSKEKINKEAVWFLSNITAGNQEQVQAVIDYSLIPLIIYHLDKGDFQTQKEAAWVISNLTISGTPQQVAFVVQQGVIPPFCKMLSVRDAQVVQVVLDGILNILKVANDQS------DLVCTMIEECGGLDLIEQLQHHENGEIYKLAYDIIDNFFNDEMEE 1517
            R   +KN S D  EMRRRR E  V+LRK KREE + KRRN+      +  +E+EE L    ++E      +V    + +  ++L A Q  RK+LS + NPPID++I+ G++P  VE L  + +  +QFEAAWALTNIASGTS QT   V AGAVP F+KLL S    V EQAVWALGNI GD    RDY ++ GV+ P L  L     ++  RN+ W + NLCR + PPP    +S  LP L  L+ + D  +L DT WALSYL DG N++IQ VI++ + R LV LL HN   V +AALRAVGNIVTG D QTQ +LN  AL +   LL  +KE I KEA W +SNITAGN+ Q+QAVID ++IP++I  L+K +F+T+KEAAW I+N T  GT +Q+ ++V QG I P C +L+V + ++VQV L+ + NILK+    S      +    M+EE  GLD +E LQ H+N +IY+ +++II+N+F+ + E+
Sbjct:    8 RIKAYKNKSLDVSEMRRRREEEGVQLRKAKREEQMFKRRNVEVTRTSSTGSELEELLTSDYMAEGPLFQDMVQAIISDDVEMQLAATQRFRKILSKEPNPPIDDVIKCGVIPKFVEFLQREDNSALQFEAAWALTNIASGTSMQTRETVNAGAVPCFIKLLESPKEEVQEQAVWALGNIAGDSADCRDYVLNCGVLTPFLNLLTKSTRLSMTRNLVWALSNLCRGRHPPPDFAKVSPCLPLLSRLLFSTDAEVLADTCWALSYLLDGPNEKIQAVIDSGVCRRLVELLDHNQNSVVSAALRAVGNIVTGDDIQTQVILNCHALPNLLHLLSSTKESIRKEACWTISNITAGNRLQIQAVIDANIIPMLIDVLNKAEFKTRKEAAWAIANATSGGTAEQIRYIVSQGAIRPLCDLLTVLNPKIVQVGLNALDNILKIGQQDSKQSGMPNPYAIMVEEAYGLDKMEFLQGHDNEQIYRKSFEIIENYFSADDED 499          
BLAST of Importin subunit alpha vs. Ensembl Nematostella
Match: EDO42228 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S260])

HSP 1 Score: 62.7734 bits (151), Expect = 3.492e-10
Identity = 70/310 (22.58%), Postives = 124/310 (40.00%), Query Frame = 3
Query:  366 DNLIQSGIMPILVECLDNDAHPNIQFE--AAWALTNIASGTSEQTNAVVQAGAVPLFLKLLGSTHSNVCEQAVWALGNIIGDGPTLRDYAISLGVVAPLLKFLNADVPITFLRNVTWVIVNLCRNKDPPPSPVTISELLPALRFLIQNIDTNILVDTVWALSYLTDGGNDQIQMVIEADIVRFLVPLLSHNDVKVQTAALRAVGNIVTGTDEQTQYVLNFDALSHFPQLLQHSKEKINKEAVWFLSNITAGNQEQVQAVI-DYSLIPLIIYHLDKGDFQTQKEAAWVISNLTISGTPQQVAFVVQQGVIP 1286
            + ++++ I+P LV  L   A  N  ++  AA+ L  +A  +++    VV  GA+   +  L      V E A WALG I      L    +  G V PLL     +  +   R  +  + ++C++       V  +  +  L  +I N D  +      ALS +     D  +MV+EA+I   ++  L   D  V       +  I   T E  Q ++N   ++     +      +    V  L  + A ++    +VI    ++ L I   ++ +   Q  AAW +  +    TP+    V    V+P
Sbjct:   77 EAVVKADILPQLVYSL---AEQNRFYKKAAAFVLRAVAKHSAQHAQCVVDCGALDALVICLEEFDPGVKEAAAWALGYIARHNAELSQAVVDAGAV-PLLVLCIQEPELALKRIASSALSDICKHSPELAQTVVDAGAIAHLAQMILNTDAKLKRQVFSALSQIAKHSVDLAEMVVEAEIFPAVLNCLKDPDEYVCKNVATLIREIAKHTPELAQLIVNAGGVAAVVDYVGDKSGNVRLPGVMMLGYVAAHSENLAMSVIVSKGVVQLSISIAEESEDHIQAAAAWALGQIG-RHTPEHAKAVAVANVLP 381          

HSP 2 Score: 62.003 bits (149), Expect = 6.027e-10
Identity = 59/267 (22.10%), Postives = 114/267 (42.70%), Query Frame = 3
Query:  372 LIQSGIMPILVECLDNDAHPNIQFEAAWALTNIASGTSEQTNAVVQAGAVPLFLKLLGSTHSNVCEQAVWALGNIIGDGPTLRDYAISLGVVAPLLKF-LNADVPITFLRNVTWVIVNLCRNKDPPPSPVTISELLPALRFLIQNIDTNILVDTVWALSYLTDGGNDQIQMVIEADIVRFLVPLLSHNDVKVQTAALRAVGNIVTGTDEQTQYVLNFDALSHFP-QLLQHSKEKINKEAVWFLSNITAGNQEQVQAVIDYSLIPLII 1166
            ++  G +  LV CL+ +  P ++  AAWAL  IA   +E + AVV AGAVPL +  +      +   A  AL +I    P L    +  G +A L +  LN D  +   R V   +  + ++       V  +E+ PA+   +++ D  +  +    +  +     +  Q+++ A  V  +V  +      V+   +  +G +   ++     V+    +      + + S++ I   A W L  I     E  +AV   +++P ++
Sbjct:  121 VVDCGALDALVICLE-EFDPGVKEAAAWALGYIARHNAELSQAVVDAGAVPLLVLCIQEPELALKRIASSALSDICKHSPELAQTVVDAGAIAHLAQMILNTDAKLK--RQVFSALSQIAKHSVDLAEMVVEAEIFPAVLNCLKDPDEYVCKNVATLIREIAKHTPELAQLIVNAGGVAAVVDYVGDKSGNVRLPGVMMLGYVAAHSENLAMSVIVSKGVVQLSISIAEESEDHIQAAAAWALGQIGRHTPEHAKAVAVANVLPKLL 384          

HSP 3 Score: 61.6178 bits (148), Expect = 7.615e-10
Identity = 50/203 (24.63%), Postives = 95/203 (46.80%), Query Frame = 3
Query:  783 LRFLIQNIDTNILVDTVWALSYLTDGGNDQIQMVIEADIVRFLVPLLSHNDVKVQTAALRAVGNIVTGTDEQTQYVLNFDALSHFPQLLQHSKEKINKEAVWFLSNITAGNQEQVQAVIDYSLIPLIIYHLDKGDFQTQKEAAWVISNLTISGTPQQVAFVVQQGVIPPFCKMLSVRDAQVVQVVLDGILNILKVANDQSDLV 1391
            LR L+ +I   I      AL  L +  +D  + V++ADI+  LV  L+  +   + AA   +  +   + +  Q V++  AL      L+     + + A W L  I   N E  QAV+D   +PL++  + + +   ++ A+  +S++    +P+    VV  G I    +M+   DA++ + V   +  I K + D +++V
Sbjct:   46 LRPLLLDIVPTIQQTAALALGRLANYNDDLAEAVVKADILPQLVYSLAEQNRFYKKAAAFVLRAVAKHSAQHAQCVVDCGALDALVICLEEFDPGVKEAAAWALGYIARHNAELSQAVVDAGAVPLLVLCIQEPELALKRIASSALSDIC-KHSPELAQTVVDAGAIAHLAQMILNTDAKLKRQVFSALSQIAKHSVDLAEMV 247          
BLAST of Importin subunit alpha vs. Ensembl Medaka
Match: kpna4 (karyopherin subunit alpha 4 [Source:NCBI gene;Acc:101173644])

HSP 1 Score: 667.537 bits (1721), Expect = 0.000e+0
Identity = 338/512 (66.02%), Postives = 406/512 (79.30%), Query Frame = 3
Query:   84 RRNMHKNASKDTDEMRRRRVEGNVELRKNKREETLQKRRNLPSLE-ADENEIEEPLQMGN--LSEIVANSTNPNPTVRLEAIQAARKLLSSDKNPPIDNLIQSGIMPILVECLDNDAHPNIQFEAAWALTNIASGTSEQTNAVVQAGAVPLFLKLLGSTHSNVCEQAVWALGNIIGDGPTLRDYAISLGVVAPLLKFLNADVPITFLRNVTWVIVNLCRNKDPPPSPVTISELLPALRFLIQNIDTNILVDTVWALSYLTDGGNDQIQMVIEADIVRFLVPLLSHNDVKVQTAALRAVGNIVTGTDEQTQYVLNFDALSHFPQLLQHSKEKINKEAVWFLSNITAGNQEQVQAVIDYSLIPLIIYHLDKGDFQTQKEAAWVISNLTISGTPQQVAFVVQQGVIPPFCKMLSVRDAQVVQVVLDGILNILKVANDQSDLVCTMIEECGGLDLIEQLQHHENGEIYKLAYDIIDNFF-NDEMEETENQNGMEMRSGVDASDMNALQQNNTGGFN 1607
            R    KN  +D + MRR+R E  VELRKNKR+E L KRRN+P  +  ++++++   +  N  L  IV N+T+ N  V+L A+QAARKLLSSD+NPPID+LI+SGI+PILV CLD D +P++QFEAAWALTNIASGTSEQT AVVQ+ AVPLFL+LL S H NVCEQAVWALGNIIGDGP  RDY ISLGVV PLL F++  +PITFLRNVTWV+VNLCR+KDPPP   TI E+LPAL  LI + D +ILVDTVWALSYLTD GN+QIQMVI++ IV  LVPLLSH +VKVQTAALRAVGNIVTGTDEQTQ VLN DALSHFP LL H KEKINKEAVWFLSNITAGNQ+QVQAVID  L+P+II+ LDKGDF TQKEAAW ISNLTISG   QVA ++++ VIPPFC +L+V+DAQVVQVVLDG+ NILK+A+D+++ +  +IEECGGL+ +EQLQ+HEN +IYKLAY+IID +F +D+++E             D S +    Q  T GFN
Sbjct:   11 RLKNFKNKGRDLETMRRQRTEVVVELRKNKRDEHLLKRRNVPHEDLCEDSDLDGDFRSQNTSLEAIVQNATSDNQGVQLSAVQAARKLLSSDRNPPIDDLIKSGILPILVHCLDRDDNPSLQFEAAWALTNIASGTSEQTQAVVQSNAVPLFLRLLHSPHQNVCEQAVWALGNIIGDGPQCRDYVISLGVVKPLLSFISPSIPITFLRNVTWVMVNLCRHKDPPPPMETIQEILPALCVLIHHTDVSILVDTVWALSYLTDAGNEQIQMVIDSGIVPHLVPLLSHQEVKVQTAALRAVGNIVTGTDEQTQVVLNCDALSHFPALLTHPKEKINKEAVWFLSNITAGNQQQVQAVIDAKLVPMIIHLLDKGDFGTQKEAAWAISNLTISGRKDQVAHLIEKQVIPPFCNLLTVKDAQVVQVVLDGLSNILKMADDEAETIANLIEECGGLEKVEQLQNHENEDIYKLAYEIIDQYFSSDDIDE-------------DTSLVPETIQGGTYGFN 509          
BLAST of Importin subunit alpha vs. Ensembl Medaka
Match: kpna3 (karyopherin subunit alpha 3 [Source:NCBI gene;Acc:101166015])

HSP 1 Score: 659.062 bits (1699), Expect = 0.000e+0
Identity = 331/512 (64.65%), Postives = 401/512 (78.32%), Query Frame = 3
Query:   84 RRNMHKNASKDTDEMRRRRVEGNVELRKNKREETLQKRRNLPSLEA-DENEIEEPLQMGN--LSEIVANSTNPNPTVRLEAIQAARKLLSSDKNPPIDNLIQSGIMPILVECLDNDAHPNIQFEAAWALTNIASGTSEQTNAVVQAGAVPLFLKLLGSTHSNVCEQAVWALGNIIGDGPTLRDYAISLGVVAPLLKFLNADVPITFLRNVTWVIVNLCRNKDPPPSPVTISELLPALRFLIQNIDTNILVDTVWALSYLTDGGNDQIQMVIEADIVRFLVPLLSHNDVKVQTAALRAVGNIVTGTDEQTQYVLNFDALSHFPQLLQHSKEKINKEAVWFLSNITAGNQEQVQAVIDYSLIPLIIYHLDKGDFQTQKEAAWVISNLTISGTPQQVAFVVQQGVIPPFCKMLSVRDAQVVQVVLDGILNILKVANDQSDLVCTMIEECGGLDLIEQLQHHENGEIYKLAYDIIDNFFNDEMEETENQNGMEMRSGVDASDMNALQQNNTGGFNF 1610
            R    KN  +D + MRR R E  VELRKNKR+E L K+RN+P  E+ ++++++   +  N  L +I+ N+T+ N  V+L A+QAARKLLSSD+NPPID+LI+SGI+PILV+CL+ D +P++QFEAAWALTNIASGTS QT AVV++ AVPLFL+LL S H NVCEQAVWALGNIIGDGP  RDY ISLGVV PLL F++  +PITFLRNVTWVIVNLCRNKDPPP   T+ E+LPAL  LI + D NILVDTVWALSYLTDGGN+QIQMVI++ +V FLVPLLSH +VKVQTAALRAVGNIVTGTDEQTQ VLN D L HFP LL H KEKINKEAVWFLSNITAGNQ+QVQAVID  LIP+II+ L KGDF TQKEAAW ISNLTISG   QV F+V+  VIPPFC +LSV+D+QVVQVVLDG+ NIL +A  ++  +  +IEECGGL+ IEQLQ HEN +IYKLA++IID +F+ ++ + E+ N +   +     + +      T  FNF
Sbjct:   11 RIKSFKNKGRDVETMRRHRNEVTVELRKNKRDEHLLKKRNVPQEESLEDSDVDSDFKGQNVTLDDILQNATSDNAVVQLSAVQAARKLLSSDRNPPIDDLIKSGILPILVKCLERDDNPSLQFEAAWALTNIASGTSAQTQAVVKSNAVPLFLRLLHSPHQNVCEQAVWALGNIIGDGPQCRDYVISLGVVKPLLSFISPSIPITFLRNVTWVIVNLCRNKDPPPPMETVQEILPALCMLIYHTDLNILVDTVWALSYLTDGGNEQIQMVIDSGVVPFLVPLLSHQEVKVQTAALRAVGNIVTGTDEQTQVVLNCDVLLHFPNLLSHPKEKINKEAVWFLSNITAGNQQQVQAVIDAGLIPMIIHQLAKGDFGTQKEAAWAISNLTISGRKDQVEFLVEHNVIPPFCSLLSVKDSQVVQVVLDGLKNILIMAGQEASTIAEIIEECGGLEKIEQLQQHENEDIYKLAFEIIDQYFSGDIFD-EDPNLIPETTQGGTFNFDPASNMQTKKFNF 521          
BLAST of Importin subunit alpha vs. Ensembl Medaka
Match: kpna2 (importin subunit alpha-1 [Source:NCBI gene;Acc:101160561])

HSP 1 Score: 452.21 bits (1162), Expect = 1.782e-150
Identity = 242/490 (49.39%), Postives = 315/490 (64.29%), Query Frame = 3
Query:   84 RRNMHKNASKDTDEMRRRRVEGNVELRKNKREETLQKRRNLPSLEADENEIEEPLQ----------MGNLSEIVANSTNPNPTVRLEAIQAARKLLSSDKNPPIDNLIQSGIMPILVECLDNDAHPNIQFEAAWALTNIASGTSEQTNAVVQAGAVPLFLKLLGSTHSNVCEQAVWALGNIIGDGPTLRDYAISLGVVAPLLKFL-----NADVPITFLRNVTWVIVNLCRNKDPPPSPVTISELLPALRFLIQNIDTNILVDTVWALSYLTDGGNDQIQMVIEADIVRFLVPLLSHNDVKVQTAALRAVGNIVTGTDEQTQYVLNFDALSHFPQLLQHSKEKINKEAVWFLSNITAGNQEQVQAVIDYSLIPLIIYHLDKGDFQTQKEAAWVISNLTISGTPQQVAFVVQQGVIPPFCKMLSVRDAQVVQVVLDGILNILKVAND--QSDLVCTMIEECGGLDLIEQLQHHENGEIYKLAYDIIDNFFN 1502
            R    KN  KD +E+RRRRVE NVELRK K+++ + KRRN+    A   E   PLQ             + EIV+   + +   +L+A QAARKLLS +K+PPID +I +G++P  V  L     P IQFEA+WALTNIASGTS+QT AVV+ GA+P F+ L+ S H ++ EQAVWALGNI GDG  LRD  I  G VAPLL  L     N   P  FLRNVTW + NLCRNK+P P    + +++PAL  L+ + D  +L D  WA+SYLTDG ND+I++V    ++  LV LL   ++ V T ALRA+GNIVTGTDEQTQ VL+  AL  FP+LL+H K  I KEA W LSNITAG   Q+Q VID  L+P ++  L + D++TQKEA W ++N T  GT QQV ++VQ  V+ P   +LS +D + V V+LD I NI    +   +SD +  MIEE GGLD IE LQ HEN  +YK A ++I+ +F+
Sbjct:    6 RLTQFKNKGKDANELRRRRVEVNVELRKAKKDDQMFKRRNV---AAAPEEATSPLQERTQNCQNSRQWTIEEIVSGLNSGSRESQLQATQAARKLLSREKHPPIDQMISAGLIPKFVAFLGLMDFPPIQFEASWALTNIASGTSDQTAAVVEGGAIPAFINLVTSPHLHISEQAVWALGNIAGDGSALRDRVIKHGAVAPLLSLLAVPDLNVFTP-GFLRNVTWTLSNLCRNKNPSPPISAVQQVMPALIRLLHHDDREVLADACWAVSYLTDGSNDRIEIVAGTGLIPRLVKLLGFEELPVITPALRAIGNIVTGTDEQTQAVLDAGALFMFPKLLRHKKPNIQKEAAWTLSNITAGKDSQIQEVIDAGLVPYLVDLLVRADYKTQKEAVWAVTNFTSGGTVQQVVYLVQANVLEPLLNLLSSKDCKTVLVILDAITNIFLAGDKIGESDKLSLMIEEFGGLDKIEALQAHENEMVYKAALNLIEKYFS 491          
BLAST of Importin subunit alpha vs. Ensembl Medaka
Match: KPNA2 (karyopherin subunit alpha 2 [Source:NCBI gene;Acc:101159727])

HSP 1 Score: 421.779 bits (1083), Expect = 1.002e-138
Identity = 224/486 (46.09%), Postives = 317/486 (65.23%), Query Frame = 3
Query:   84 RRNMHKNASKDTDEMRRRRVEGNVELRKNKREETLQKRRNL-----PSLEADENEIEEPLQMGNLSEIVANSTNPNPTVRLEAIQAARKLLSSDKNPPIDNLIQSGIMPILVECLDNDAHPNIQFEAAWALTNIASGTSEQTNAVVQAGAVPLFLKLLGSTHSNVCEQAVWALGNIIGDGPTLRDYAISLGVVAPLLKFL-NADVPI---TFLRNVTWVIVNLCRNKDPPPSPVTISELLPALRFLIQNIDTNILVDTVWALSYLTDGGNDQIQMVIEADIVRFLVPLLSHNDVKVQTAALRAVGNIVTGTDEQTQYVLNFDALSHFPQLLQHSKEKINKEAVWFLSNITAGNQEQVQAVIDYSLIPLIIYHLDKGDFQTQKEAAWVISNLTISGTPQQVAFVVQQGVIPPFCKMLSVRDAQVVQVVLDGILNILKVANDQSDL--VCTMIEECGGLDLIEQLQHHENGEIYKLAYDIIDNFFNDE 1508
            R ++ KN  K   E  RRR E  VELRK K++E + KRR +      SL  D+N      Q  ++ EIV    + N   +++A+QAAR  LS +K+PP+D +I +G++P LV  L    +P IQFEAAWALTNIASGTS QT +V+  GAVP F+ L+ S H ++ +QA+WALGNI GDG   RD  I  G + PLL  L  +D+ +   ++LRNVTW + NLCR+K+P P   ++ ++LP L  L+ + D  +L DT  ALS+LTDG N++I+MV++ D V  LV LLS  DV + T ALR +GNIVTGTDEQTQ VLN  AL+ FP LL +    I KEA W +SNITAG   Q+Q VI+  L+P+++  L +GD++TQ+EA W ++N T  GT  QVA++V    + P  ++L ++D++V+ V+LD I NIL+++ D  ++  V  +IE  GGLD +E LQ H+N  +YK + +IID +F+ E
Sbjct:   11 RIHLFKNKGKCALESLRRRAEVKVELRKAKKDEQIFKRRAIQQDDPASLLHDKNYRG---QCWSVEEIVGAVNSQNLEHQVQAVQAARAFLSREKSPPVDGIIAAGLIPTLVGFLALSENPPIQFEAAWALTNIASGTSHQTKSVIAGGAVPAFVSLISSPHQHISQQAIWALGNIAGDGADSRDLVIHHGGLQPLLALLETSDLSVFGSSYLRNVTWALSNLCRHKNPAPPLASVRQMLPVLAHLLHHDDREVLADTCRALSHLTDGANERIEMVVDTDCVPRLVQLLSCEDVSIVTPALRTIGNIVTGTDEQTQCVLNAGALAVFPVLLGYPNPNIQKEAAWAVSNITAGKSSQIQEVINAGLVPMLVDILQQGDYKTQREAVWAVTNYTSGGTVDQVAYLVHCNALEPLIQLLHIKDSRVILVILDAIDNILQMSKDTGEVEKVRLLIEGLGGLDTLEALQSHDNEAVYKSSLNIIDKYFSQE 493          
BLAST of Importin subunit alpha vs. Ensembl Medaka
Match: kpna6 (karyopherin subunit alpha 6 [Source:NCBI gene;Acc:101172668])

HSP 1 Score: 420.624 bits (1080), Expect = 5.147e-138
Identity = 235/499 (47.09%), Postives = 323/499 (64.73%), Query Frame = 3
Query:   84 RRNMHKNASKDTDEMRRRRVEGNVELRKNKREETLQKRRNLPSLEADENEIEEPLQMGNLSEIVANST----------NPNPTVRLEAIQAARKLLSSDKNPPIDNLIQS-GIMPILVECLDNDAHPNIQFEAAWALTNIASGTSEQTNAVVQAGAVPLFLKLLGSTHSNVCEQAVWALGNIIGDGPTLRDYAISLGVVAPLLKFLNADVPITFLRNVTWVIVNLCRNKDPPPSPVTISELLPALRFLIQNIDTNILVDTVWALSYLTDGGNDQIQMVIEADIVRFLVPLLSHNDVKVQTAALRAVGNIVTGTDEQTQYVLNFDALSHFPQLLQHSKEKINKEAVWFLSNITAGNQEQVQAVIDYSLIPLIIYHLDKGDFQTQKEAAWVISNLTISGTPQQVAFVVQQGVIPPFCKMLSVRDAQVVQVVLDGILNILKVANDQ---------SDLVCTMIEECGGLDLIEQLQHHENGEIYKLAYDIIDNFFNDEMEET 1520
            R N +KN + + +EMRRRR E  ++LRK KRE+ L KRRN+  L  +E   E PL   ++S  V              + +P ++L   Q  RKLLS + NPPID +I + G++   VE L    +  +QFEAAWALTNIASGTS QT  V++AGAVP+F++LL S + +V EQAVWALGNI GD    RD+ ++  ++ PLL  L     +T  RN  W + NLCR K+PPP+   +S  LP L  L+ + D ++L D  WALSYL+DG ND+IQ VI++ + R LV LL H D KV + ALRAVGNIVTG D QTQ VLN  AL     LL  +KE I KEA W +SNITAGN+ Q+QAVID ++ P++I  L K +F+T+KEAAW I+N T  GTP+Q+ ++V  G I P C +L+V D+++VQV L+G+ NIL++   +         ++  C++IEE  GLD IE LQ H+N EIY+ A+D+I+++F  E E++
Sbjct:   13 RMNRYKNKALNPEEMRRRREEEGIQLRKQKREQQLFKRRNVDVLNEEEAMFESPLVDPSVSSPVTEGVITRDMVEMLFSEDPELQLATTQKFRKLLSKEPNPPIDEVINTAGVVERFVEFLKMTTNCTLQFEAAWALTNIASGTSLQTKTVIEAGAVPIFIELLNSDYEDVQEQAVWALGNIAGDSAVCRDFVLNCNILPPLLTLLTKSTRLTMTRNAVWALSNLCRGKNPPPAFEKVSPCLPVLSRLLFSSDPDLLADACWALSYLSDGPNDKIQAVIDSGVCRRLVELLMHTDYKVASPALRAVGNIVTGDDIQTQVVLNCSALPCLLHLLSSAKESIRKEACWTISNITAGNRAQIQAVIDANIFPVLIGILQKAEFRTRKEAAWAITNATSGGTPEQIRYLVNLGCIKPLCDLLTVMDSKIVQVALNGLENILRLGEQEAKQENSGTGTNPYCSLIEEAYGLDKIEFLQSHDNQEIYQKAFDLIEHYFGVEDEDS 511          
BLAST of Importin subunit alpha vs. Planmine SMEST
Match: SMESG000058125.1 (SMESG000058125.1)

HSP 1 Score: 1051.2 bits (2717), Expect = 0.000e+0
Identity = 512/512 (100.00%), Postives = 512/512 (100.00%), Query Frame = 3
Query:   75 MSDRRNMHKNASKDTDEMRRRRVEGNVELRKNKREETLQKRRNLPSLEADENEIEEPLQMGNLSEIVANSTNPNPTVRLEAIQAARKLLSSDKNPPIDNLIQSGIMPILVECLDNDAHPNIQFEAAWALTNIASGTSEQTNAVVQAGAVPLFLKLLGSTHSNVCEQAVWALGNIIGDGPTLRDYAISLGVVAPLLKFLNADVPITFLRNVTWVIVNLCRNKDPPPSPVTISELLPALRFLIQNIDTNILVDTVWALSYLTDGGNDQIQMVIEADIVRFLVPLLSHNDVKVQTAALRAVGNIVTGTDEQTQYVLNFDALSHFPQLLQHSKEKINKEAVWFLSNITAGNQEQVQAVIDYSLIPLIIYHLDKGDFQTQKEAAWVISNLTISGTPQQVAFVVQQGVIPPFCKMLSVRDAQVVQVVLDGILNILKVANDQSDLVCTMIEECGGLDLIEQLQHHENGEIYKLAYDIIDNFFNDEMEETENQNGMEMRSGVDASDMNALQQNNTGGFNF 1610
            MSDRRNMHKNASKDTDEMRRRRVEGNVELRKNKREETLQKRRNLPSLEADENEIEEPLQMGNLSEIVANSTNPNPTVRLEAIQAARKLLSSDKNPPIDNLIQSGIMPILVECLDNDAHPNIQFEAAWALTNIASGTSEQTNAVVQAGAVPLFLKLLGSTHSNVCEQAVWALGNIIGDGPTLRDYAISLGVVAPLLKFLNADVPITFLRNVTWVIVNLCRNKDPPPSPVTISELLPALRFLIQNIDTNILVDTVWALSYLTDGGNDQIQMVIEADIVRFLVPLLSHNDVKVQTAALRAVGNIVTGTDEQTQYVLNFDALSHFPQLLQHSKEKINKEAVWFLSNITAGNQEQVQAVIDYSLIPLIIYHLDKGDFQTQKEAAWVISNLTISGTPQQVAFVVQQGVIPPFCKMLSVRDAQVVQVVLDGILNILKVANDQSDLVCTMIEECGGLDLIEQLQHHENGEIYKLAYDIIDNFFNDEMEETENQNGMEMRSGVDASDMNALQQNNTGGFNF
Sbjct:    1 MSDRRNMHKNASKDTDEMRRRRVEGNVELRKNKREETLQKRRNLPSLEADENEIEEPLQMGNLSEIVANSTNPNPTVRLEAIQAARKLLSSDKNPPIDNLIQSGIMPILVECLDNDAHPNIQFEAAWALTNIASGTSEQTNAVVQAGAVPLFLKLLGSTHSNVCEQAVWALGNIIGDGPTLRDYAISLGVVAPLLKFLNADVPITFLRNVTWVIVNLCRNKDPPPSPVTISELLPALRFLIQNIDTNILVDTVWALSYLTDGGNDQIQMVIEADIVRFLVPLLSHNDVKVQTAALRAVGNIVTGTDEQTQYVLNFDALSHFPQLLQHSKEKINKEAVWFLSNITAGNQEQVQAVIDYSLIPLIIYHLDKGDFQTQKEAAWVISNLTISGTPQQVAFVVQQGVIPPFCKMLSVRDAQVVQVVLDGILNILKVANDQSDLVCTMIEECGGLDLIEQLQHHENGEIYKLAYDIIDNFFNDEMEETENQNGMEMRSGVDASDMNALQQNNTGGFNF 512          
BLAST of Importin subunit alpha vs. Planmine SMEST
Match: SMESG000058125.1 (SMESG000058125.1)

HSP 1 Score: 1038.1 bits (2683), Expect = 0.000e+0
Identity = 506/506 (100.00%), Postives = 506/506 (100.00%), Query Frame = 3
Query:   93 MHKNASKDTDEMRRRRVEGNVELRKNKREETLQKRRNLPSLEADENEIEEPLQMGNLSEIVANSTNPNPTVRLEAIQAARKLLSSDKNPPIDNLIQSGIMPILVECLDNDAHPNIQFEAAWALTNIASGTSEQTNAVVQAGAVPLFLKLLGSTHSNVCEQAVWALGNIIGDGPTLRDYAISLGVVAPLLKFLNADVPITFLRNVTWVIVNLCRNKDPPPSPVTISELLPALRFLIQNIDTNILVDTVWALSYLTDGGNDQIQMVIEADIVRFLVPLLSHNDVKVQTAALRAVGNIVTGTDEQTQYVLNFDALSHFPQLLQHSKEKINKEAVWFLSNITAGNQEQVQAVIDYSLIPLIIYHLDKGDFQTQKEAAWVISNLTISGTPQQVAFVVQQGVIPPFCKMLSVRDAQVVQVVLDGILNILKVANDQSDLVCTMIEECGGLDLIEQLQHHENGEIYKLAYDIIDNFFNDEMEETENQNGMEMRSGVDASDMNALQQNNTGGFNF 1610
            MHKNASKDTDEMRRRRVEGNVELRKNKREETLQKRRNLPSLEADENEIEEPLQMGNLSEIVANSTNPNPTVRLEAIQAARKLLSSDKNPPIDNLIQSGIMPILVECLDNDAHPNIQFEAAWALTNIASGTSEQTNAVVQAGAVPLFLKLLGSTHSNVCEQAVWALGNIIGDGPTLRDYAISLGVVAPLLKFLNADVPITFLRNVTWVIVNLCRNKDPPPSPVTISELLPALRFLIQNIDTNILVDTVWALSYLTDGGNDQIQMVIEADIVRFLVPLLSHNDVKVQTAALRAVGNIVTGTDEQTQYVLNFDALSHFPQLLQHSKEKINKEAVWFLSNITAGNQEQVQAVIDYSLIPLIIYHLDKGDFQTQKEAAWVISNLTISGTPQQVAFVVQQGVIPPFCKMLSVRDAQVVQVVLDGILNILKVANDQSDLVCTMIEECGGLDLIEQLQHHENGEIYKLAYDIIDNFFNDEMEETENQNGMEMRSGVDASDMNALQQNNTGGFNF
Sbjct:    1 MHKNASKDTDEMRRRRVEGNVELRKNKREETLQKRRNLPSLEADENEIEEPLQMGNLSEIVANSTNPNPTVRLEAIQAARKLLSSDKNPPIDNLIQSGIMPILVECLDNDAHPNIQFEAAWALTNIASGTSEQTNAVVQAGAVPLFLKLLGSTHSNVCEQAVWALGNIIGDGPTLRDYAISLGVVAPLLKFLNADVPITFLRNVTWVIVNLCRNKDPPPSPVTISELLPALRFLIQNIDTNILVDTVWALSYLTDGGNDQIQMVIEADIVRFLVPLLSHNDVKVQTAALRAVGNIVTGTDEQTQYVLNFDALSHFPQLLQHSKEKINKEAVWFLSNITAGNQEQVQAVIDYSLIPLIIYHLDKGDFQTQKEAAWVISNLTISGTPQQVAFVVQQGVIPPFCKMLSVRDAQVVQVVLDGILNILKVANDQSDLVCTMIEECGGLDLIEQLQHHENGEIYKLAYDIIDNFFNDEMEETENQNGMEMRSGVDASDMNALQQNNTGGFNF 506          
BLAST of Importin subunit alpha vs. Planmine SMEST
Match: SMESG000058125.1 (SMESG000058125.1)

HSP 1 Score: 1013.83 bits (2620), Expect = 0.000e+0
Identity = 495/495 (100.00%), Postives = 495/495 (100.00%), Query Frame = 3
Query:  126 MRRRRVEGNVELRKNKREETLQKRRNLPSLEADENEIEEPLQMGNLSEIVANSTNPNPTVRLEAIQAARKLLSSDKNPPIDNLIQSGIMPILVECLDNDAHPNIQFEAAWALTNIASGTSEQTNAVVQAGAVPLFLKLLGSTHSNVCEQAVWALGNIIGDGPTLRDYAISLGVVAPLLKFLNADVPITFLRNVTWVIVNLCRNKDPPPSPVTISELLPALRFLIQNIDTNILVDTVWALSYLTDGGNDQIQMVIEADIVRFLVPLLSHNDVKVQTAALRAVGNIVTGTDEQTQYVLNFDALSHFPQLLQHSKEKINKEAVWFLSNITAGNQEQVQAVIDYSLIPLIIYHLDKGDFQTQKEAAWVISNLTISGTPQQVAFVVQQGVIPPFCKMLSVRDAQVVQVVLDGILNILKVANDQSDLVCTMIEECGGLDLIEQLQHHENGEIYKLAYDIIDNFFNDEMEETENQNGMEMRSGVDASDMNALQQNNTGGFNF 1610
            MRRRRVEGNVELRKNKREETLQKRRNLPSLEADENEIEEPLQMGNLSEIVANSTNPNPTVRLEAIQAARKLLSSDKNPPIDNLIQSGIMPILVECLDNDAHPNIQFEAAWALTNIASGTSEQTNAVVQAGAVPLFLKLLGSTHSNVCEQAVWALGNIIGDGPTLRDYAISLGVVAPLLKFLNADVPITFLRNVTWVIVNLCRNKDPPPSPVTISELLPALRFLIQNIDTNILVDTVWALSYLTDGGNDQIQMVIEADIVRFLVPLLSHNDVKVQTAALRAVGNIVTGTDEQTQYVLNFDALSHFPQLLQHSKEKINKEAVWFLSNITAGNQEQVQAVIDYSLIPLIIYHLDKGDFQTQKEAAWVISNLTISGTPQQVAFVVQQGVIPPFCKMLSVRDAQVVQVVLDGILNILKVANDQSDLVCTMIEECGGLDLIEQLQHHENGEIYKLAYDIIDNFFNDEMEETENQNGMEMRSGVDASDMNALQQNNTGGFNF
Sbjct:    1 MRRRRVEGNVELRKNKREETLQKRRNLPSLEADENEIEEPLQMGNLSEIVANSTNPNPTVRLEAIQAARKLLSSDKNPPIDNLIQSGIMPILVECLDNDAHPNIQFEAAWALTNIASGTSEQTNAVVQAGAVPLFLKLLGSTHSNVCEQAVWALGNIIGDGPTLRDYAISLGVVAPLLKFLNADVPITFLRNVTWVIVNLCRNKDPPPSPVTISELLPALRFLIQNIDTNILVDTVWALSYLTDGGNDQIQMVIEADIVRFLVPLLSHNDVKVQTAALRAVGNIVTGTDEQTQYVLNFDALSHFPQLLQHSKEKINKEAVWFLSNITAGNQEQVQAVIDYSLIPLIIYHLDKGDFQTQKEAAWVISNLTISGTPQQVAFVVQQGVIPPFCKMLSVRDAQVVQVVLDGILNILKVANDQSDLVCTMIEECGGLDLIEQLQHHENGEIYKLAYDIIDNFFNDEMEETENQNGMEMRSGVDASDMNALQQNNTGGFNF 495          
BLAST of Importin subunit alpha vs. Planmine SMEST
Match: SMESG000055942.1 (SMESG000055942.1)

HSP 1 Score: 926.391 bits (2393), Expect = 0.000e+0
Identity = 454/463 (98.06%), Postives = 454/463 (98.06%), Query Frame = 3
Query:   75 MSDRRNMHKNASKDTDEMRRRRVEGNVELRKNKREETLQKRRNLPSLEADENEIEEPLQMGNLSEIVANSTNPNPTVRLEAIQAARKLLSSDKNPPIDNLIQSGIMPILVECLDNDAHPNIQFEAAWALTNIASGTSEQTNAVVQAGAVPLFLKLLGSTHSNVCEQAVWALGNIIGDGPTLRDYAISLGVVAPLLKFLNADVPITFLRNVTWVIVNLCRNKDPPPSPVTISELLPALRFLIQNIDTNILVDTVWALSYLTDGGNDQIQMVIEADIVRFLVPLLSHNDVKVQTAALRAVGNIVTGTDEQTQYVLNFDALSHFPQLLQHSKEKINKEAVWFLSNITAGNQEQVQAVIDYSLIPLIIYHLDKGDFQTQKEAAWVISNLTISGTPQQVAFVVQQGVIPPFCKMLSVRDAQVVQVVLDGILNILKVANDQSDLVCTMIEECGGLDLIEQLQHHENGEI 1463
            MSDRRNMHKNASKDTDEMRRRRVEGNVELRKNKREETLQKRRNLPSLEADENEIEEPLQMGNLSEIVANSTNPNPTVRLEAIQAARKLLSSDKNPPIDNLIQSGIMPILVECLDNDAHPNIQFEAAWALTNIASGTSEQTNAVVQAGAVPLFLKLLGSTHSNVCEQAVWALGNIIGDGPTLRDYAISLGVVAPLLKF         LRNVTWVIVNLCRNKDPPPSPVTISELLPALRFLIQNIDTNILVDTVWALSYLTDGGNDQIQMVIEADIVRFLVPLLSHNDVKVQTAALRAVGNIVTGTDEQTQYVLNFDALSHFPQLLQHSKEKINKEAVWFLSNITAGNQEQVQAVIDYSLIPLIIYHLDKGDFQTQKEAAWVISNLTISGTPQQVAFVVQQGVIPPFCKMLSVRDAQVVQVVLDGILNILKVANDQSDLVCTMIEECGGLDLIEQLQHHENGEI
Sbjct:    1 MSDRRNMHKNASKDTDEMRRRRVEGNVELRKNKREETLQKRRNLPSLEADENEIEEPLQMGNLSEIVANSTNPNPTVRLEAIQAARKLLSSDKNPPIDNLIQSGIMPILVECLDNDAHPNIQFEAAWALTNIASGTSEQTNAVVQAGAVPLFLKLLGSTHSNVCEQAVWALGNIIGDGPTLRDYAISLGVVAPLLKFFKCRCTNNLLRNVTWVIVNLCRNKDPPPSPVTISELLPALRFLIQNIDTNILVDTVWALSYLTDGGNDQIQMVIEADIVRFLVPLLSHNDVKVQTAALRAVGNIVTGTDEQTQYVLNFDALSHFPQLLQHSKEKINKEAVWFLSNITAGNQEQVQAVIDYSLIPLIIYHLDKGDFQTQKEAAWVISNLTISGTPQQVAFVVQQGVIPPFCKMLSVRDAQVVQVVLDGILNILKVANDQSDLVCTMIEECGGLDLIEQLQHHENGEI 463          
BLAST of Importin subunit alpha vs. Planmine SMEST
Match: SMESG000063514.1 (SMESG000063514.1)

HSP 1 Score: 330.487 bits (846), Expect = 6.412e-104
Identity = 179/488 (36.68%), Postives = 287/488 (58.81%), Query Frame = 3
Query:   81 DRRNMHKNASKDTDEMRRRRVEGNVELRKNKREETLQKRRNL-------PSLEADENEIEEPLQMGNLSEIVANSTNPNPTVRLEAIQAARKLLSSDKNPPIDNLIQSGIMPILVECLDNDAHPNIQFEAAWALTNIASGTSEQTNAVVQAGAVPLFLKLLGSTHSNVCEQAVWALGNIIGDGPTLRDYAISLGVVA----PLLKFLNADVPITFLRNVTWVIVNLCRNKDPPPSPVTISELLPALRFLIQNI-DTNILVDTVWALSYLTDGGNDQIQMVIEADIVRFLVPLLSHNDVKVQTAALRAVGNIVTGTDEQTQYVLNFDALSHFPQLLQHSKEKINKEAVWFLSNITAGNQEQVQAVIDYSLIPLIIYHLDKGDFQTQKEAAWVISNLTISGTPQQVAFVVQQGVIPPFCKMLSVRDAQVVQVVLDGILNILKVAND--QSDLVCTMIEECGGLDLIEQLQHHENGEIYKLAYDIIDNFFN 1502
            +RRN++KN  KD + +RR R + +VE+RK K+E+ LQKRRN+        ++E    E  + ++  N++EI     + N T  L+A  + RKLLS  KNPPI++  ++G +P+LV+ + ++ +  + FE+AWALTNIASG ++ T AVV+AGA+P+F+KL+  +   V EQ++WAL NI GD    RD  +  G++      +L+F +    +  LR+V W+I NLCR+K        I ELLP +R ++  I D     D  WALSY  D  +D I  +I  ++V  L+  L+  + ++ T +LRA+GN++ GTDEQ    +    +     LL H   ++ KE+ W LSNI AGN+ Q+QA +D  ++  ++  +  GD+++QKEAAW +SN+  S   +   +++   V      +LS  +  VV ++LD +  +   A+   Q +L     E+ GG+D+IE LQ HE+ +IY  ++DI+  F N
Sbjct:    5 NRRNLYKNGDKDFESLRRNRNDHSVEIRKAKKEDQLQKRRNIVIDDLSDENIEVSSKENVKEIKDININEIPKLLKSDNITQMLDAATSCRKLLSKQKNPPIEDFYKNGTIPLLVKIMTDNKNEILTFESAWALTNIASGDNKHTEAVVKAGAIPVFVKLMSCSTDQVSEQSIWALSNIAGDSAKYRDMIVKHGIIDVVKNCILRFWS---KLEVLRHVCWLISNLCRHKSTNFPSSGIIELLPLIREIMVEINDVACTCDLNWALSYAIDSRDDIINALIANELVPVLIANLNRQECEIVTPSLRAIGNVIAGTDEQADAAIKCGVIISVGHLLSHKNPRLVKESCWVLSNIIAGNESQIQACVDCDVMIPLLDVMRNGDYKSQKEAAWAVSNMANSANDKHKLYLLNNNVFHAIVPILSCNENDVVILLLDAVRELFTCADKIGQLELCINAFEDVGGIDIIESLQEHESVDIYTKSFDIVKEFLN 489          
The following BLAST results are available for this feature:
BLAST of Importin subunit alpha vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5
Match NameE-valueIdentityDescription
KPNA30.000e+068.58karyopherin subunit alpha 3 [Source:HGNC Symbol;Ac... [more]
KPNA40.000e+069.29karyopherin subunit alpha 4 [Source:HGNC Symbol;Ac... [more]
KPNA22.461e-15545.59karyopherin subunit alpha 2 [Source:HGNC Symbol;Ac... [more]
KPNA22.461e-15545.59karyopherin subunit alpha 2 [Source:HGNC Symbol;Ac... [more]
KPNA75.448e-13944.15karyopherin subunit alpha 7 [Source:HGNC Symbol;Ac... [more]
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BLAST of Importin subunit alpha vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 5
Match NameE-valueIdentityDescription
ima-30.000e+060.39Importin subunit alpha-3 [Source:UniProtKB/Swiss-... [more]
ima-23.447e-9336.11Importin subunit alpha-2 [Source:UniProtKB/Swiss-... [more]
ima-13.561e-2321.30Importin subunit alpha-1 [Source:UniProtKB/Swiss-... [more]
ima-13.561e-2321.30Importin subunit alpha-1 [Source:UniProtKB/Swiss-... [more]
F53B2.53.940e-2225.96pep chromosome:WBcel235:IV:12528529:12531166:-1 ge... [more]
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BLAST of Importin subunit alpha vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Kap-alpha30.000e+067.08gene:FBgn0027338 transcript:FBtr0301189[more]
Kap-alpha30.000e+067.08gene:FBgn0027338 transcript:FBtr0082106[more]
Kap-alpha30.000e+067.08gene:FBgn0027338 transcript:FBtr0082108[more]
Kap-alpha30.000e+067.08gene:FBgn0027338 transcript:FBtr0082107[more]
Kap-alpha11.184e-14845.66gene:FBgn0024889 transcript:FBtr0074881[more]
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BLAST of Importin subunit alpha vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
kpna40.000e+069.48karyopherin alpha 4 (importin alpha 3) [Source:ZFI... [more]
kpna30.000e+067.43karyopherin alpha 3 (importin alpha 4) [Source:ZFI... [more]
kpna21.193e-15548.28karyopherin alpha 2 (RAG cohort 1, importin alpha ... [more]
kpna65.895e-14046.41karyopherin alpha 6 (importin alpha 7) [Source:ZFI... [more]
kpna52.095e-13646.60karyopherin alpha 5 (importin alpha 6) [Source:NCB... [more]
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BLAST of Importin subunit alpha vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5
Match NameE-valueIdentityDescription
kpna30.000e+068.25karyopherin alpha 3 (importin alpha 4) [Source:NCB... [more]
kcnn10.000e+067.77potassium channel, calcium activated intermediate/... [more]
kcnn10.000e+066.13potassium channel, calcium activated intermediate/... [more]
kpna30.000e+065.94karyopherin alpha 3 (importin alpha 4) [Source:NCB... [more]
kcnn10.000e+067.22potassium channel, calcium activated intermediate/... [more]
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BLAST of Importin subunit alpha vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Kpna40.000e+066.47karyopherin (importin) alpha 4 [Source:MGI Symbol;... [more]
Kpna40.000e+066.47karyopherin (importin) alpha 4 [Source:MGI Symbol;... [more]
Kpna30.000e+066.67karyopherin (importin) alpha 3 [Source:MGI Symbol;... [more]
Gm101848.318e-15946.34predicted pseudogene 10184 [Source:MGI Symbol;Acc:... [more]
Kpna28.318e-15946.34karyopherin (importin) alpha 2 [Source:MGI Symbol;... [more]
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BLAST of Importin subunit alpha vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|O35343|IMA3_MOUSE0.000e+066.47Importin subunit alpha-3 OS=Mus musculus OX=10090 ... [more]
sp|O35344|IMA4_MOUSE0.000e+066.67Importin subunit alpha-4 OS=Mus musculus OX=10090 ... [more]
sp|O00505|IMA4_HUMAN0.000e+068.58Importin subunit alpha-4 OS=Homo sapiens OX=9606 G... [more]
sp|O00629|IMA3_HUMAN0.000e+069.29Importin subunit alpha-3 OS=Homo sapiens OX=9606 G... [more]
sp|Q19969|IMA3_CAEEL0.000e+060.39Importin subunit alpha-3 OS=Caenorhabditis elegans... [more]
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BLAST of Importin subunit alpha vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
A0A210PVP20.000e+067.39Importin subunit alpha OS=Mizuhopecten yessoensis ... [more]
T1IVG41.644e-870.87Importin subunit alpha OS=Strigamia maritima OX=12... [more]
Q6QJF20.000e+071.13Importin subunit alpha OS=Aplysia californica OX=6... [more]
V4CR360.000e+070.75Importin subunit alpha OS=Lottia gigantea OX=22516... [more]
A0A2C9JNB00.000e+070.71Importin subunit alpha OS=Biomphalaria glabrata OX... [more]
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BLAST of Importin subunit alpha vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
kpna40.000e+070.11karyopherin subunit alpha 4 [Source:NCBI gene;Acc:... [more]
kpna30.000e+068.67karyopherin subunit alpha 3 [Source:NCBI gene;Acc:... [more]
KPNA30.000e+068.46importin subunit alpha-4-like [Source:NCBI gene;Ac... [more]
kpna30.000e+065.91karyopherin subunit alpha 3 [Source:NCBI gene;Acc:... [more]
KPNA30.000e+069.47importin subunit alpha-4-like [Source:NCBI gene;Ac... [more]
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BLAST of Importin subunit alpha vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 5
Match NameE-valueIdentityDescription
kpna40.000e+068.80karyopherin alpha 4 (importin alpha 3) [Source:ZFI... [more]
kpna76.551e-14847.40karyopherin alpha 7 (importin alpha 8) [Source:ZFI... [more]
ENSPMAT00000005568.11.836e-10243.09pep scaffold:Pmarinus_7.0:GL477092:38612:43101:1 g... [more]
kpna64.821e-5151.45karyopherin alpha 6 (importin alpha 7) [Source:ZFI... [more]
ENSPMAT00000008519.12.095e-2844.44pep scaffold:Pmarinus_7.0:GL480915:29739:34392:1 g... [more]
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BLAST of Importin subunit alpha vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 1
Match NameE-valueIdentityDescription
SRP19.908e-12844.22Karyopherin alpha homolog; forms a dimer with kary... [more]
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BLAST of Importin subunit alpha vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 5
Match NameE-valueIdentityDescription
EDO319404.113e-16967.48Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO291612.644e-16864.27Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO306483.318e-15548.16Importin subunit alpha [Source:UniProtKB/TrEMBL;A... [more]
EDO383371.892e-13947.36Importin subunit alpha [Source:UniProtKB/TrEMBL;A... [more]
EDO422283.492e-1022.58Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
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BLAST of Importin subunit alpha vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5
Match NameE-valueIdentityDescription
kpna40.000e+066.02karyopherin subunit alpha 4 [Source:NCBI gene;Acc:... [more]
kpna30.000e+064.65karyopherin subunit alpha 3 [Source:NCBI gene;Acc:... [more]
kpna21.782e-15049.39importin subunit alpha-1 [Source:NCBI gene;Acc:101... [more]
KPNA21.002e-13846.09karyopherin subunit alpha 2 [Source:NCBI gene;Acc:... [more]
kpna65.147e-13847.09karyopherin subunit alpha 6 [Source:NCBI gene;Acc:... [more]
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BLAST of Importin subunit alpha vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5
Match NameE-valueIdentityDescription
SMESG000058125.10.000e+0100.00SMESG000058125.1[more]
SMESG000058125.10.000e+0100.00SMESG000058125.1[more]
SMESG000058125.10.000e+0100.00SMESG000058125.1[more]
SMESG000055942.10.000e+098.06SMESG000055942.1[more]
SMESG000063514.16.412e-10436.68SMESG000063514.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30013177 ID=SMED30013177|Name=Importin subunit alpha|organism=Schmidtea mediterranea sexual|type=transcript|length=2476bp
TTTTAGTTTAAAAAAATTTGTTTATATTACTTGTTTATTTATAACTAGTT
TCGATTAACATAGGAAGTTCAATCATGTCTGACAGGCGTAATATGCATAA
AAATGCTAGTAAGGATACTGATGAGATGAGAAGAAGAAGAGTTGAAGGTA
ATGTGGAGCTACGCAAAAATAAGCGTGAAGAAACACTACAAAAACGTAGA
AACTTACCATCTCTTGAAGCCGATGAAAATGAGATTGAAGAACCACTTCA
AATGGGCAATTTAAGTGAAATAGTGGCAAATTCTACTAATCCTAATCCAA
CCGTTAGATTAGAAGCAATTCAAGCTGCAAGAAAATTATTGTCGAGTGAT
AAAAATCCTCCTATTGACAATCTCATACAATCGGGAATAATGCCAATTTT
AGTAGAATGTTTAGATAATGACGCGCATCCAAATATACAATTTGAAGCTG
CATGGGCATTGACTAATATTGCATCTGGAACATCAGAGCAGACAAACGCC
GTTGTACAAGCTGGTGCTGTACCTCTATTTTTAAAGTTATTAGGATCAAC
TCATAGCAATGTCTGTGAACAAGCAGTTTGGGCTTTAGGAAATATAATTG
GTGATGGCCCTACATTAAGAGACTATGCAATCAGTCTAGGCGTAGTAGCT
CCTTTACTCAAATTTTTAAATGCAGATGTACCCATAACCTTTTTAAGAAA
TGTTACATGGGTCATTGTAAACTTATGTCGTAATAAAGATCCACCGCCAA
GCCCTGTTACTATTTCAGAACTTTTGCCAGCTTTGAGATTTTTGATTCAA
AATATTGATACTAATATCCTGGTAGATACGGTTTGGGCTCTTTCATATTT
GACAGACGGTGGAAATGATCAAATCCAGATGGTTATTGAAGCTGATATAG
TGCGCTTCTTAGTACCATTATTATCGCATAACGATGTTAAAGTACAAACT
GCGGCGCTTAGAGCAGTAGGTAATATTGTTACAGGAACGGATGAACAGAC
CCAATACGTTTTAAATTTTGATGCACTTTCACATTTTCCTCAGTTATTGC
AACATTCTAAAGAAAAGATAAATAAAGAGGCTGTTTGGTTTTTATCAAAT
ATCACTGCTGGTAATCAAGAGCAAGTGCAAGCAGTTATTGATTATTCGCT
GATTCCATTAATTATTTATCATTTGGACAAAGGGGATTTTCAAACACAAA
AAGAAGCTGCTTGGGTAATTTCAAATTTAACAATTAGTGGTACTCCACAA
CAAGTTGCATTTGTTGTGCAACAAGGTGTTATACCTCCATTTTGTAAAAT
GTTGTCTGTTCGAGATGCTCAAGTCGTTCAGGTTGTACTTGATGGTATAT
TAAATATCCTTAAAGTAGCTAATGATCAATCGGATCTTGTTTGTACAATG
ATTGAAGAGTGTGGTGGCTTAGATTTAATAGAGCAACTTCAGCATCACGA
AAATGGTGAAATTTACAAATTAGCTTACGATATTATCGATAATTTTTTTA
ACGACGAGATGGAAGAAACCGAAAACCAAAATGGAATGGAAATGCGTTCG
GGGGTTGATGCAAGTGATATGAATGCATTGCAACAAAATAACACTGGTGG
ATTTAACTTTTAAACAGATTGATGACTTTTAATGAATATGATATGCTGCA
GGATGATTTATGATGTTATTGGATATAGACTGTATGTGGTGCTTCACATT
CTTTTGCCTTTTTTAATTTCATTTTAAATTTTCTGAATAGCCTTAAATGG
ATGATTAGTCGACTAGTCATATGTTGTGTGTTTTGCATTTATGTTTGTTT
ATTGTATCCAAGTTCTTTCAGATTTGATCTATGTTTGAGAATGCTCATGG
TTATTAAGCACATGTAGAGATGTATGATGTCAATTTTTCCAAGGTAAATT
CCTTATTTCCATAAGCAGAATTTCCTTTATTTTTATCCGTTGTCTTTCTT
TTTCATGAATTTTATCTTTTGTATGACATTTTGTTGTGTTGAGTGCAAGG
CAGTATTTGTTTGGTATAGCGATTGAGTTTGTTGGTATCAAAATGGTTTA
ATGTCAAGCTAGGTTAAATTTCAATCTAATAAATAGATTAAGTTGAGAGA
AATTAGTTTAGTAGAATTTGTTGGATTTTGAATGAGTAATATAACGAATG
TTTCATGAAAAGTTTTTATGATTTTTGTTATACTATATTTGTGGAACTGA
TTGATCAACATTATTATTTTTATCAGACAAAAAGTATTTCGTTGAATAGA
AAGCTTGCATTGTTCAAAAGAATTGATTTTATAAAGTTAAAATAGTAGAT
TATCGTTGGTAACTATCGGTTTCTTGAATATTATCAGTAAATCTTGCATC
GCGTGTAATTTGAAATATGTTTTAAGGCGCATATTTGCGGTGTGTTATTA
CATAAGTACTAAGAATCTTGGATTACGTTAAATAATTGAAATTCGTAATA
ATTTAAATATATTTACAGAATTTGAA
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protein sequence of SMED30013177-orf-1

>SMED30013177-orf-1 ID=SMED30013177-orf-1|Name=SMED30013177-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=513bp
MSDRRNMHKNASKDTDEMRRRRVEGNVELRKNKREETLQKRRNLPSLEAD
ENEIEEPLQMGNLSEIVANSTNPNPTVRLEAIQAARKLLSSDKNPPIDNL
IQSGIMPILVECLDNDAHPNIQFEAAWALTNIASGTSEQTNAVVQAGAVP
LFLKLLGSTHSNVCEQAVWALGNIIGDGPTLRDYAISLGVVAPLLKFLNA
DVPITFLRNVTWVIVNLCRNKDPPPSPVTISELLPALRFLIQNIDTNILV
DTVWALSYLTDGGNDQIQMVIEADIVRFLVPLLSHNDVKVQTAALRAVGN
IVTGTDEQTQYVLNFDALSHFPQLLQHSKEKINKEAVWFLSNITAGNQEQ
VQAVIDYSLIPLIIYHLDKGDFQTQKEAAWVISNLTISGTPQQVAFVVQQ
GVIPPFCKMLSVRDAQVVQVVLDGILNILKVANDQSDLVCTMIEECGGLD
LIEQLQHHENGEIYKLAYDIIDNFFNDEMEETENQNGMEMRSGVDASDMN
ALQQNNTGGFNF*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: cellular component
TermDefinition
GO:0042025host cell nucleus
GO:0005737cytoplasm
GO:0005634nucleus
GO:0005643nuclear pore
GO:0005654nucleoplasm
GO:0005829cytosol
GO:0070062extracellular exosome
Vocabulary: molecular function
TermDefinition
GO:0061608nuclear import signal receptor activity
GO:0005515protein binding
GO:0008565protein transporter activity
GO:0005488binding
GO:0008139nuclear localization sequence binding
Vocabulary: INTERPRO
TermDefinition
IPR036975Importin-a_IBB_sf
IPR000225Armadillo
IPR032413Arm_3
IPR024931Importing_su_alpha
IPR002652Importin-a_IBB
IPR011989ARM-like
IPR016024ARM-type_fold
Vocabulary: biological process
TermDefinition
GO:0006606protein import into nucleus
GO:0006607NLS-bearing protein import into nucleus
GO:0006810transport
GO:0015031protein transport
GO:0042542response to hydrogen peroxide
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR000225ArmadilloSMARTSM00185arm_5coord: 93..134
e-value: 9.2E-11
score: 51.8
coord: 136..176
e-value: 1.0E-9
score: 48.3
coord: 390..430
e-value: 6.9E-4
score: 28.9
coord: 347..387
e-value: 2.1E-4
score: 30.7
coord: 221..261
e-value: 21.0
score: 10.7
coord: 178..219
e-value: 24.0
score: 10.3
coord: 263..303
e-value: 1.2E-7
score: 41.5
coord: 305..345
e-value: 1.2E-6
score: 38.1
IPR000225ArmadilloPFAMPF00514Armcoord: 305..345
e-value: 1.4E-7
score: 31.3
coord: 136..174
e-value: 6.3E-12
score: 45.1
coord: 347..386
e-value: 7.3E-8
score: 32.2
coord: 391..428
e-value: 1.6E-5
score: 24.7
coord: 94..134
e-value: 1.4E-11
score: 44.0
coord: 181..219
e-value: 8.3E-5
score: 22.5
coord: 264..302
e-value: 3.6E-9
score: 36.3
IPR000225ArmadilloPROSITEPS50176ARM_REPEATcoord: 147..174
score: 8.697
IPR000225ArmadilloPROSITEPS50176ARM_REPEATcoord: 104..147
score: 10.657
IPR036975Importin-alpha, importin-beta-binding domain superfamilyGENE3DG3DSA:1.20.5.690coord: 3..44
e-value: 3.8E-14
score: 54.0
IPR002652Importin-alpha, importin-beta-binding domainPFAMPF01749IBBcoord: 4..83
e-value: 2.0E-17
score: 63.4
IPR002652Importin-alpha, importin-beta-binding domainPROSITEPS51214IBBcoord: 1..51
score: 15.291
IPR032413Atypical Arm repeatPFAMPF16186Arm_3coord: 439..485
e-value: 3.2E-21
score: 74.6
IPR024931Importin subunit alphaPIRSFPIRSF005673Importin_alphacoord: 1..512
e-value: 1.5E-200
score: 664.6
IPR011989Armadillo-like helicalGENE3DG3DSA:1.25.10.10coord: 58..477
e-value: 1.2E-183
score: 612.3
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 1..48
NoneNo IPR availablePANTHERPTHR23316:SF28IMPORTIN SUBUNIT ALPHAcoord: 3..478
NoneNo IPR availablePANTHERPTHR23316IMPORTIN ALPHAcoord: 3..478
IPR016024Armadillo-type foldSUPERFAMILYSSF48371ARM repeatcoord: 4..478