Cactin, spliceosome C complex subunit

Overview


Name	Cactin, spliceosome C complex subunit
Smed ID	SMED30013169
Length (bp)	2034

Neoblast Clusters

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Overview

Single cell RNA-seq of pluripotent neoblasts and its early progenies

We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)

Explore this single cell expression dataset with our NB Cluster Shiny App

Neoblast Population

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.

Expression of Cactin, spliceosome C complex subunit (SMED30013169) t-SNE clustered cells

Violin plots show distribution of expression levels for Cactin, spliceosome C complex subunit (SMED30013169) in cells (dots) of each of the 12 neoblast clusters.

Sub-lethal Irradiated Surviving X1 and X2 Cell Population

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of Cactin, spliceosome C complex subunit (SMED30013169) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for Cactin, spliceosome C complex subunit (SMED30013169) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

Anatomical Expression

PAGE et. al., 2020

SMED30013169

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE

PAGE Curations: 8

Expressed In	Reference Transcript	Gene Models	Published Transcript	Transcriptome	Publication
intestinal phagocyte	SMED30013169	SMESG000061791.1	Contig2041	newmark_ests	PMID:23079596 Forsthoefel et al., 2012
intestinal phagocyte	SMED30013169	SMESG000016407.1	Contig2041	newmark_ests	PMID:23079596 Forsthoefel et al., 2012
X1 cell	SMED30013169	SMESG000061791.1	SmedASXL_013553	SmedAsxl_ww_GCZZ01	PMID:26114597 Zhu et al., 2015
X2 cell	SMED30013169	SMESG000061791.1	SmedASXL_013553	SmedAsxl_ww_GCZZ01	PMID:26114597 Zhu et al., 2015
nervous system	SMED30013169	SMESG000061791.1	dd_Smed_v4_8085_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
epidermis	SMED30013169	SMESG000061791.1	dd_Smed_v4_8085_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
neoblast	SMED30013169	SMESG000061791.1	dd_Smed_v4_8085_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
parenchymal cell	SMED30013169	SMESG000061791.1	dd_Smed_v4_8085_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018

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Homology

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BLAST of Cactin, spliceosome C complex subunit vs. Ensembl Human
Match: CACTIN (cactin, spliceosome C complex subunit [Source:HGNC Symbol;Acc:HGNC:29938])

HSP 1 Score: 375.941 bits (964), Expect = 1.281e-119
Identity = 232/581 (39.93%), Postives = 329/581 (56.63%), Query Frame = 3

Query:  213 CGYTDDNNPFMDPNLTKEFVW-----------------KKKNNPVQLNCQEKQAELENVQXXXXXXXXXXXXXXXXXXXXXXAKEAQNFRG-RKSDSNFDIEQAKNRSKIRIAEGRAKPIDLLIQYVNEEENTINDNADAIIHEPTQFLVGLSKXXXXXXXXXIHEYSRNMEPGKNTQYWEDIRLITEDELKRVIKTEDDG-----RTEGVTKECVDDMKQMILQGTIDESTELLNDAKKMLETGDRRHIDVAYYEYFCSLARVLIAKKRLQERHSNNLRIKLNRLKHEQGLPIEPLFP----------SAIKPEAQVDTKPTSSKKP-------------------------------------EQKLEREEYDHSRYSPVLLSGEELGDEAIENVIYLADDDEKKLEFMRKKFIKFGSHKINQEDELIKLVQEGDEKGDLDFSEQIAIEEQSFLWSDKYRPRKPRFLNRVNTGFDWNKYNQTHYDMDNPPPKIVQGYKFNILYPDLIDKTKTPTFELTPCIDDDQYAMITFKAGPPYEDIAFKIVNREWETSERHGYKCQFYRDMLQLYFHFKRYRYRK 1745
             GYT+ +NPF D NL   F+W                 K++N  +Q   ++ + EL+ V++   E ER +  R  E E++QR KEA++F+   + + NF ++QAK RSKIRI +GRAKPIDLL +Y++ E    +D+    +HEP  FL GL+  D++DLL DI  Y   +E GKN  +W D+  ITEDE+ ++ K E  G     R EGV      D++ +    T ++   +    +  +  G   ++D+ Y+E      R  +A+ RL+ERH + LR KL +LK EQG+  EPLFP           +++PE    T P  S +                                      +Q L+  +YD  RYSP LL+  EL    ++  +   D+D ++L+  R++    G    + ED   +  +EG  + +  FS ++ +  +++LW+DKYRPRKPRF NRV+TGF+WNKYNQTHYD DNPPPKIVQGYKFNI YPDLIDK  TP + L  C D+  +A++ F AGPPYEDIAFKIVNREWE S RHG++CQF   + QL+FHFKRYRYR+
Sbjct:  192 MGYTNTDNPFGDNNLLGTFIWNKALEKKGISHLEEKELKERNKRIQ---EDNRLELQKVKQLRLEREREKAMREQELEMLQREKEAEHFKTWEEQEDNFHLQQAKLRSKIRIRDGRAKPIDLLAKYISAE----DDDLAVEMHEPYTFLNGLTVADMEDLLEDIQVYM-ELEQGKNADFWRDMTTITEDEISKLRKLEASGKGPGERREGVNASVSSDVQSVFKGKTYNQLQVIFQGIEGKIRAGGP-NLDMGYWESLLQQLRAHMARARLRERHQDVLRQKLYKLKQEQGVESEPLFPILKQEPQSPSRSLEPEDAAPTPPGPSSEGGPAEAEVDGATPTEGDGDGDGEGEGEGEAVLMEEDLIQQSLD--DYDAGRYSPRLLTAHEL---PLDAHVLEPDEDLQRLQLSRQQLQVTGDASESAEDIFFRRAKEGMGQDEAQFSVEMPLTGKAYLWADKYRPRKPRFFNRVHTGFEWNKYNQTHYDFDNPPPKIVQGYKFNIFYPDLIDKRSTPEYFLEACADNKDFAILRFHAGPPYEDIAFKIVNREWEYSHRHGFRCQFANGIFQLWFHFKRYRYRR 758

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Query:  213 CGYTDDNNPFMDPNLTKEFVW-----------------KKKNNPVQLNCQEKQAELENVQXXXXXXXXXXXXXXXXXXXXXXAKEAQNFRG-RKSDSNFDIEQAKNRSKIRIAEGRAKPIDLLIQYVNEEENTINDNADAIIHEPTQFLVGLSKXXXXXXXXXIHEYSRNMEPGKNTQYWEDIRLITEDELKRVIKTEDDG-----RTEGVTKECVDDMKQMILQGTIDESTELLNDAKKMLETGDRRHIDVAYYEYFCSLARVLIAKKRLQERHSNNLRIKLNRLKHEQGLPIEPLFP----------SAIKPEAQVDTKPTSSKKP-------------------------------------EQKLEREEYDHSRYSPVLLSGEELGDEAIENVIYLADDDEKKLEFMRKKFIKFGSHKINQEDELIKLVQEGDEKGDLDFSEQIAIEEQSFLWSDKYRPRKPRFLNRVNTGFDWNKYNQTHYDMDNPPPKIVQGYKFNILYPDLIDKTKTPTFELTPCIDDDQYAMITFKAGPPYEDIAFKIVNREWETSERHGYKCQFYRDMLQLYFHFKRYRYRK 1745
             GYT+ +NPF D NL   F+W                 K++N  +Q   ++ + EL+ V++   E ER +  R  E E++QR KEA++F+   + + NF ++QAK RSKIRI +GRAKPIDLL +Y++ E    +D+    +HEP  FL GL+  D++DLL DI  Y   +E GKN  +W D+  ITEDE+ ++ K E  G     R EGV      D++ +    T ++   +    +  +  G   ++D+ Y+E      R  +A+ RL+ERH + LR KL +LK EQG+  EPLFP           +++PE    T P  S +                                      +Q L+  +YD  RYSP LL+  EL    ++  +   D+D ++L+  R++    G    + ED   +  +EG  + +  FS ++ +  +++LW+DKYRPRKPRF NRV+TGF+WNKYNQTHYD DNPPPKIVQGYKFNI YPDLIDK  TP + L  C D+  +A++ F AGPPYEDIAFKIVNREWE S RHG++CQF   + QL+FHFKRYRYR+
Sbjct:  192 MGYTNTDNPFGDNNLLGTFIWNKALEKKGISHLEEKELKERNKRIQ---EDNRLELQKVKQLRLEREREKAMREQELEMLQREKEAEHFKTWEEQEDNFHLQQAKLRSKIRIRDGRAKPIDLLAKYISAE----DDDLAVEMHEPYTFLNGLTVADMEDLLEDIQVYM-ELEQGKNADFWRDMTTITEDEISKLRKLEASGKGPGERREGVNASVSSDVQSVFKGKTYNQLQVIFQGIEGKIRAGGP-NLDMGYWESLLQQLRAHMARARLRERHQDVLRQKLYKLKQEQGVESEPLFPILKQEPQSPSRSLEPEDAAPTPPGPSSEGGPAEAEVDGATPTEGDGDGDGEGEGEGEAVLMEEDLIQQSLD--DYDAGRYSPRLLTAHEL---PLDAHVLEPDEDLQRLQLSRQQLQVTGDASESAEDIFFRRAKEGMGQDEAQFSVEMPLTGKAYLWADKYRPRKPRFFNRVHTGFEWNKYNQTHYDFDNPPPKIVQGYKFNIFYPDLIDKRSTPEYFLEACADNKDFAILRFHAGPPYEDIAFKIVNREWEYSHRHGFRCQFANGIFQLWFHFKRYRYRR 758

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Query:  213 CGYTDDNNPFMDPNLTKEFVW-----------------KKKNNPVQLNCQEKQAELENVQXXXXXXXXXXXXXXXXXXXXXXAKEAQNFRG-RKSDSNFDIEQAKNRSKIRIAEGRAKPIDLLIQYVNEEENTINDNADAIIHEPTQFLVGLSKXXXXXXXXXIHEYSRNMEPGKNTQYWEDIRLITEDELKRVIKTEDDG-----RTEGVTKECVDDMKQMILQGTIDESTELLNDAKKMLETGDRRHIDVAYYEYFCSLARVLIAKKRLQERHSNNLRIKLNRLKHEQGLPIEPLFP----------SAIKPEAQVDTKPTSSKKP-------------------------------------EQKLEREEYDHSRYSPVLLSGEELGDEAIENVIYLADDDEKKLEFMRKKFIKFGSHKINQEDELIKLVQEGDEKGDLDFSEQIAIEEQSFLWSDKYRPRKPRFLNRVNTGFDWNKYNQTHYDMDNPPPKIVQGYKFNILYPDLIDKTKTPTFELTPCIDDDQYAMITFKAGPPYEDIAFKIVNREWETSERHGYKCQFYRDMLQLYFHFKRYRYRK 1745
             GYT+ +NPF D NL   F+W                 K++N  +Q   ++ + EL+ V++   E ER +  R  E E++QR KEA++F+   + + NF ++QAK RSKIRI +GRAKPIDLL +Y++ E    +D+    +HEP  FL GL+  D++DLL DI  Y   +E GKN  +W D+  ITEDE+ ++ K E  G     R EGV      D++ +    T ++   +    +  +  G   ++D+ Y+E      R  +A+ RL+ERH + LR KL +LK EQG+  EPLFP           +++PE    T P  S +                                      +Q L+  +YD  RYSP LL+  EL    ++  +   D+D ++L+  R++    G    + ED   +  +EG  + +  FS ++ +  +++LW+DKYRPRKPRF NRV+TGF+WNKYNQTHYD DNPPPKIVQGYKFNI YPDLIDK  TP + L  C D+  +A++ F AGPPYEDIAFKIVNREWE S RHG++CQF   + QL+FHFKRYRYR+
Sbjct:  192 MGYTNTDNPFGDNNLLGTFIWNKALEKKGISHLEEKELKERNKRIQ---EDNRLELQKVKQLRLEREREKAMREQELEMLQREKEAEHFKTWEEQEDNFHLQQAKLRSKIRIRDGRAKPIDLLAKYISAE----DDDLAVEMHEPYTFLNGLTVADMEDLLEDIQVYM-ELEQGKNADFWRDMTTITEDEISKLRKLEASGKGPGERREGVNASVSSDVQSVFKGKTYNQLQVIFQGIEGKIRAGGP-NLDMGYWESLLQQLRAHMARARLRERHQDVLRQKLYKLKQEQGVESEPLFPILKQEPQSPSRSLEPEDAAPTPPGPSSEGGPAEAEVDGATPTEGDGDGDGEGEGEGEAVLMEEDLIQQSLD--DYDAGRYSPRLLTAHEL---PLDAHVLEPDEDLQRLQLSRQQLQVTGDASESAEDIFFRRAKEGMGQDEAQFSVEMPLTGKAYLWADKYRPRKPRFFNRVHTGFEWNKYNQTHYDFDNPPPKIVQGYKFNIFYPDLIDKRSTPEYFLEACADNKDFAILRFHAGPPYEDIAFKIVNREWEYSHRHGFRCQFANGIFQLWFHFKRYRYRR 758

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Query:  213 CGYTDDNNPFMDPNLTKEFVW-----------------KKKNNPVQLNCQEKQAELENVQXXXXXXXXXXXXXXXXXXXXXXAKEAQNFRG-RKSDSNFDIEQAKNRSKIRIAEGRAKPIDLLIQYVNEEENTINDNADAIIHEPTQFLVGLSKXXXXXXXXXIHEYSRNMEPGKNTQYWEDIRLITEDELKRVIKTEDDG-----RTEGVTKECVDDMKQMILQGTIDESTELLNDAKKMLETGDRRHIDVAYYEYFCSLARVLIAKKRLQERHSNNLRIKLNRLKHEQGLPIEPLFP----------SAIKPEAQVDTKPTSSKKP-------------------------------------EQKLEREEYDHSRYSPVLLSGEELGDEAIENVIYLADDDEKKLEFMRKKFIKFGSHKINQEDELIKLVQEGDEKGDLDFSEQIAIEEQSFLWSDKYRPRKPRFLNRVNTGFDWNKYNQTHYDMDNPPPKIVQGYKFNILYPDLIDKTKTPTFELTPCIDDDQYAMITFKAGPPYEDIAFKIVNREWETSERHGYKCQFYRDMLQLYFHFKRYRYRK 1745
             GYT+ +NPF D NL   F+W                 K++N  +Q   ++ + EL+ V++   E ER +  R  E E++QR KEA++F+   + + NF ++QAK RSKIRI +GRAKPIDLL +Y++ E    +D+    +HEP  FL GL+  D++DLL DI  Y   +E GKN  +W D+  ITEDE+ ++ K E  G     R EGV      D++ +    T ++   +    +  +  G   ++D+ Y+E      R  +A+ RL+ERH + LR KL +LK EQG+  EPLFP           +++PE    T P  S +                                      +Q L+  +YD  RYSP LL+  EL    ++  +   D+D ++L+  R++    G    + ED   +  +EG  + +  FS ++ +  +++LW+DKYRPRKPRF NRV+TGF+WNKYNQTHYD DNPPPKIVQGYKFNI YPDLIDK  TP + L  C D+  +A++ F AGPPYEDIAFKIVNREWE S RHG++CQF   + QL+FHFKRYRYR+
Sbjct:  192 MGYTNTDNPFGDNNLLGTFIWNKALEKKGISHLEEKELKERNKRIQ---EDNRLELQKVKQLRLEREREKAMREQELEMLQREKEAEHFKTWEEQEDNFHLQQAKLRSKIRIRDGRAKPIDLLAKYISAE----DDDLAVEMHEPYTFLNGLTVADMEDLLEDIQVYM-ELEQGKNADFWRDMTTITEDEISKLRKLEASGKGPGERREGVNASVSSDVQSVFKGKTYNQLQVIFQGIEGKIRAGGP-NLDMGYWESLLQQLRAHMARARLRERHQDVLRQKLYKLKQEQGVESEPLFPILKQEPQSPSRSLEPEDAAPTPPGPSSEGGPAEAEVDGATPTEGDGDGDGEGEGEGEAVLMEEDLIQQSLD--DYDAGRYSPRLLTAHEL---PLDAHVLEPDEDLQRLQLSRQQLQVTGDASESAEDIFFRRAKEGMGQDEAQFSVEMPLTGKAYLWADKYRPRKPRFFNRVHTGFEWNKYNQTHYDFDNPPPKIVQGYKFNIFYPDLIDKRSTPEYFLEACADNKDFAILRFHAGPPYEDIAFKIVNREWEYSHRHGFRCQFANGIFQLWFHFKRYRYRR 758

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BLAST of Cactin, spliceosome C complex subunit vs. Ensembl Human
Match: CACTIN (cactin, spliceosome C complex subunit [Source:HGNC Symbol;Acc:HGNC:29938])

HSP 1 Score: 250.366 bits (638), Expect = 2.766e-77
Identity = 114/210 (54.29%), Postives = 150/210 (71.43%), Query Frame = 3

Query: 1116 EEYDHSRYSPVLLSGEELGDEAIENVIYLADDDEKKLEFMRKKFIKFGSHKINQEDELIKLVQEGDEKGDLDFSEQIAIEEQSFLWSDKYRPRKPRFLNRVNTGFDWNKYNQTHYDMDNPPPKIVQGYKFNILYPDLIDKTKTPTFELTPCIDDDQYAMITFKAGPPYEDIAFKIVNREWETSERHGYKCQFYRDMLQLYFHFKRYRYRK 1745
            ++YD  RYSP LL+  EL    ++  +   D+D ++L+  R++    G    + ED   +  +EG  + +  FS ++ +  +++LW+DKYRPRKPRF NRV+TGF+WNKYNQTHYD DNPPPKIVQGYKFNI YPDLIDK  TP + L  C D+  +A++ F AGPPYEDIAFKIVNREWE S RHG++CQF   + QL+FHFKRYRYR+
Sbjct:   85 DDYDAGRYSPRLLTAHEL---PLDAHVLEPDEDLQRLQLSRQQLQVTGDASESAEDIFFRRAKEGMGQDEAQFSVEMPLTGKAYLWADKYRPRKPRFFNRVHTGFEWNKYNQTHYDFDNPPPKIVQGYKFNIFYPDLIDKRSTPEYFLEACADNKDFAILRFHAGPPYEDIAFKIVNREWEYSHRHGFRCQFANGIFQLWFHFKRYRYRR 291

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BLAST of Cactin, spliceosome C complex subunit vs. Ensembl Celegans
Match: cacn-1 (Cactin [Source:UniProtKB/Swiss-Prot;Acc:G5EG14])

HSP 1 Score: 275.789 bits (704), Expect = 5.158e-83
Identity = 204/580 (35.17%), Postives = 286/580 (49.31%), Query Frame = 3

Query:  219 YTDDNNPFMDPNLTKEFVWKKKN--------NPVQLNCQEKQAELENVQXXXXXXXXXXXXXXXXXXXXXXAKEAQNFRGRKSDSN---FDIEQAKNRSKIRIAEGRAKPIDLLIQYVN--EEENTINDNADAIIHEPTQFLVGLSKXXX--XXXXXXIHEYSRNMEPGKNTQYWEDIRLITEDEL-KRVIKTEDDGRTEGVTKECVDDMKQMILQGTIDESTELLN--DAKKMLETGDRRHIDVAYYEYFCSLARVLIAKKRLQERHSNNLRIKLNRLKHEQGLPI-----EPLFPSA-IKPEAQVDTKPTS-----------SKKPEQKLE------------------------------REEYDHSRYSPVLLS------GEELGDEAIENVIYLADDDEKKLEFMRKKFIKFGSHKINQEDELIKLVQEGDEKGDLDFSEQIAIEEQSFLWSDKYRPRKPRFLNRVNTGFDWNKYNQTHYDMDNPPPKIVQGYKFNILYPDLIDKTKTPTFELTPCIDDDQYAMITFKAGPPYEDIAFKIVNREWETSERHGYKCQFYRDMLQLYFHFKRYRYRK 1745
            YT+ NNPF D  LT+ FVW KK            ++  Q  Q   +N+    +           ++++    ++A    G+ SD+    F ++Q K R++IRI +GRAK IDLL +Y    +E        D  +  P ++L    K     +DL+ DI  Y       KN  +W D+  I EDE+ K+  +   D     V      +++ M    +IDE  +L +  DAK    +G++      Y++      +V IA+KRL+E H   LR++L  +K EQ   I     E L P A + P+ ++  +              SKK  +K++                              RE Y    YSP  +S      G E+ DE   +V  L +   +    +                +++ + +EG E  +  F  +  +  Q  LWSDKYRPRKP +LNRV TGFDWNKYNQTHYD DNPPPKIVQGYKFNI YPDL+D T  P F LT C D D +A+I FKAGPPYEDIAFK+VNREWET  ++GYKCQF   + QL+F FK+YRYR+
Sbjct:   90 YTNLNNPFNDTKLTQTFVWGKKLEREGKSGLTQDEITKQTSQRIRKNLHEAAEFKRIRDSRAAAKEDMEMMKRDADLRAGQISDTKEREFQMDQIKERTRIRIDQGRAKAIDLLSRYARFADENPHTAKIPDFELENPMEYLKASCKSVDDYEDLIEDIKTYREVDGWAKNETWWMDVTRIAEDEIQKKAAQNRGD-----VHASVQTEVQNMFKNKSIDELLKLEDQMDAKIRGNSGNK-----GYWQDLDDQLKVFIARKRLREHHGRVLRLQLAIIKEEQKKEIQQQESEELLPVAEVPPQVKIQKEEEEEEEEDEDDEKISKKVRRKIDVQTLDDPELDEPERERKWRALTGDQLDDVTRELYRIGCYSPTYISADDTMPGIEILDEQA-DVDNLTERRNRNRGTLPSSSAASSGAPQGASSKMMAIAREGMEADESIFGAEEQLAAQRHLWSDKYRPRKPTYLNRVQTGFDWNKYNQTHYDQDNPPPKIVQGYKFNIFYPDLLDMTVAPRFGLTSCEDPD-FAIIRFKAGPPYEDIAFKVVNREWETLHKNGYKCQFQNGVFQLWFMFKKYRYRR 657

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Query:  219 YTDDNNPFMDPNLTKEFVWKKKN--------NPVQLNCQEKQAELENVQXXXXXXXXXXXXXXXXXXXXXXAKEAQNFRGRKSDSN---FDIEQAKNRSKIRIAEGRAKPIDLLIQYVN--EEENTINDNADAIIHEPTQFLVGLSKXXX--XXXXXXIHEYSRNMEPGKNTQYWEDIRLITEDEL-KRVIKTEDDGRTEGVTKECVDDMKQMILQGTIDESTELLN--DAKKMLETGDRRHIDVAYYEYFCSLARVLIAKKRLQERHSNNLRIKLNRLKHEQGLPI-----EPLFPSA-IKPEAQVDTKPTS-----------SKKPEQKLE------------------------------REEYDHSRYSPVLLS------GEELGDEAIENVIYLADDDEKKLEFMRKKFIKFGSHKINQEDELIKLVQEGDEKGDLDFSEQIAIEEQSFLWSDKYRPRKPRFLNRVNTGFDWNKYNQTHYDMDNPPPKIVQGYKFNILYPDLIDKTKTPTFELTPCIDDDQYAMITFKAGPPYEDIAFKIVNREWETSERHGYKCQFYRDMLQLYFHFKRYRYRK 1745
            YT+ NNPF D  LT+ FVW KK            ++  Q  Q   +N+    +           ++++    ++A    G+ SD+    F ++Q K R++IRI +GRAK IDLL +Y    +E        D  +  P ++L    K     +DL+ DI  Y       KN  +W D+  I EDE+ K+  +   D     V      +++ M    +IDE  +L +  DAK    +G++      Y++      +V IA+KRL+E H   LR++L  +K EQ   I     E L P A + P+ ++  +              SKK  +K++                              RE Y    YSP  +S      G E+ DE   +V  L +   +    +                +++ + +EG E  +  F  +  +  Q  LWSDKYRPRKP +LNRV TGFDWNKYNQTHYD DNPPPKIVQGYKFNI YPDL+D T  P F LT C D D +A+I FKAGPPYEDIAFK+VNREWET  ++GYKCQF   + QL+F FK+YRYR+
Sbjct:   90 YTNLNNPFNDTKLTQTFVWGKKLEREGKSGLTQDEITKQTSQRIRKNLHEAAEFKRIRDSRAAAKEDMEMMKRDADLRAGQISDTKEREFQMDQIKERTRIRIDQGRAKAIDLLSRYARFADENPHTAKIPDFELENPMEYLKASCKSVDDYEDLIEDIKTYREVDGWAKNETWWMDVTRIAEDEIQKKAAQNRGD-----VHASVQTEVQNMFKNKSIDELLKLEDQMDAKIRGNSGNK-----GYWQDLDDQLKVFIARKRLREHHGRVLRLQLAIIKEEQKKEIQQQESEELLPVAEVPPQVKIQKEEEEEEEEDEDDEKISKKVRRKIDVQTLDDPELDEPERERKWRALTGDQLDDVTRELYRIGCYSPTYISADDTMPGIEILDEQA-DVDNLTERRNRNRGTLPSSSAASSGAPQGASSKMMAIAREGMEADESIFGAEEQLAAQRHLWSDKYRPRKPTYLNRVQTGFDWNKYNQTHYDQDNPPPKIVQGYKFNIFYPDLLDMTVAPRFGLTSCEDPD-FAIIRFKAGPPYEDIAFKVVNREWETLHKNGYKCQFQNGVFQLWFMFKKYRYRR 657

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BLAST of Cactin, spliceosome C complex subunit vs. Ensembl Celegans
Match: cacn-1 (Cactin [Source:UniProtKB/Swiss-Prot;Acc:G5EG14])

HSP 1 Score: 227.254 bits (578), Expect = 3.154e-68
Identity = 141/351 (40.17%), Postives = 185/351 (52.71%), Query Frame = 3

Query:  852 DAKKMLETGDRRHIDVAYYEYFCSLARVLIAKKRLQERHSNNLRIKLNRLKHEQGLPI-----EPLFPSA-IKPEAQVDTKPTS-----------SKKPEQKLE------------------------------REEYDHSRYSPVLLS------GEELGDEAIENVIYLADDDEKKLEFMRKKFIKFGSHKINQEDELIKLVQEGDEKGDLDFSEQIAIEEQSFLWSDKYRPRKPRFLNRVNTGFDWNKYNQTHYDMDNPPPKIVQGYKFNILYPDLIDKTKTPTFELTPCIDDDQYAMITFKAGPPYEDIAFKIVNREWETSERHGYKCQFYRDMLQLYFHFKRYRYRK 1745
            DAK    +G++      Y++      +V IA+KRL+E H   LR++L  +K EQ   I     E L P A + P+ ++  +              SKK  +K++                              RE Y    YSP  +S      G E+ DE   +V  L +   +    +                +++ + +EG E  +  F  +  +  Q  LWSDKYRPRKP +LNRV TGFDWNKYNQTHYD DNPPPKIVQGYKFNI YPDL+D T  P F LT C D D +A+I FKAGPPYEDIAFK+VNREWET  ++GYKCQF   + QL+F FK+YRYR+
Sbjct:    2 DAKIRGNSGNK-----GYWQDLDDQLKVFIARKRLREHHGRVLRLQLAIIKEEQKKEIQQQESEELLPVAEVPPQVKIQKEEEEEEEEDEDDEKISKKVRRKIDVQTLDDPELDEPERERKWRALTGDQLDDVTRELYRIGCYSPTYISADDTMPGIEILDEQA-DVDNLTERRNRNRGTLPSSSAASSGAPQGASSKMMAIAREGMEADESIFGAEEQLAAQRHLWSDKYRPRKPTYLNRVQTGFDWNKYNQTHYDQDNPPPKIVQGYKFNIFYPDLLDMTVAPRFGLTSCEDPD-FAIIRFKAGPPYEDIAFKVVNREWETLHKNGYKCQFQNGVFQLWFMFKKYRYRR 345

[Close]

BLAST of Cactin, spliceosome C complex subunit vs. Ensembl Celegans
Match: cacn-1 (Cactin [Source:UniProtKB/Swiss-Prot;Acc:G5EG14])

HSP 1 Score: 216.468 bits (550), Expect = 3.662e-66
Identity = 99/154 (64.29%), Postives = 118/154 (76.62%), Query Frame = 3

Query: 1284 ELIKLVQEGDEKGDLDFSEQIAIEEQSFLWSDKYRPRKPRFLNRVNTGFDWNKYNQTHYDMDNPPPKIVQGYKFNILYPDLIDKTKTPTFELTPCIDDDQYAMITFKAGPPYEDIAFKIVNREWETSERHGYKCQFYRDMLQLYFHFKRYRYRK 1745
            +++ + +EG E  +  F  +  +  Q  LWSDKYRPRKP +LNRV TGFDWNKYNQTHYD DNPPPKIVQGYKFNI YPDL+D T  P F LT C D D +A+I FKAGPPYEDIAFK+VNREWET  ++GYKCQF   + QL+F FK+YRYR+
Sbjct:   44 KMMAIAREGMEADESIFGAEEQLAAQRHLWSDKYRPRKPTYLNRVQTGFDWNKYNQTHYDQDNPPPKIVQGYKFNIFYPDLLDMTVAPRFGLTSCEDPD-FAIIRFKAGPPYEDIAFKVVNREWETLHKNGYKCQFQNGVFQLWFMFKKYRYRR 196

[Close]

BLAST of Cactin, spliceosome C complex subunit vs. Ensembl Fly
Match: cactin (gene:FBgn0031114 transcript:FBtr0340400)

HSP 1 Score: 327.791 bits (839), Expect = 5.839e-102
Identity = 215/558 (38.53%), Postives = 319/558 (57.17%), Query Frame = 3

Query:  219 YTDDNNPFMDPNLTKEFVWKKK----------NNPVQLNCQEKQAE----LENVQXXXXXXXXXXXXXXXXXXXXXXAKEAQNFR-GRKSDSNFDIEQAKNRSKIRIAEGRAKPIDLLIQYVNEEENTINDNADAIIHEPTQFLVGLSKXXXXXXXXXIHEYSRNMEPGKNTQYWEDIRLITEDELKRVIKTEDDG-----RTEGVTKECVDDMKQMILQGTIDESTELLNDAKKMLETGDRRHIDVAYYEYFCSLARVLIAKKRLQERHSNNLRIKLNRLKHEQGLPI--EPLFPSAIKPEAQV---------DTKPTSSKKPEQKLER--EEYDHSRYSPVLL----------SGEELGDEAIENVIYLADDDEKKLEFMRKKFIKFGSHKIN------QEDELIKLVQEGDEKGDLDFSEQIAIEEQSFLWSDKYRPRKPRFLNRVNTGFDWNKYNQTHYDMDNPPPKIVQGYKFNILYPDLIDKTKTPTFELTPCIDDDQYAMITFKAGPPYEDIAFKIVNREWETSERHGYKCQFYRDMLQLYFHFKRYRYRK 1745
            Y++++NPF D NLT  F W KK             V++   +KQ E    LE V++R +E E  R+ R  +  + QRAKEA  FR  ++ +  F +EQA+ RS+IRI +GRAKPIDLL QYV      + +  +  +HEP   L GL   +L+DLLVDI  Y   +E GK+  +W D+  I +DEL+R  K E +      R +G+ +  V D+   I +G   +  E +    +   +G    +D++Y+E   S  +  +A+ RL++RH   LR KL+ LK E       E + P   + E +          +  P   + P  +L +    Y    YSP  +            E++ +   E ++Y  +DDE++ +  R++ +     +++      QE  +    ++G +  + +FS +  ++    L +DKYRPRKPR+ NRV+TGF+WNKYNQTHYDMDNPPPKIVQGYKFNI YPDL+DK++TP + LTPC D+  +A++ F  GPPYEDIAFKIVNREWE S + G++CQF+ ++ QL+FHFKRYRYR+
Sbjct:  167 YSNEDNPFGDSNLTSTFHWGKKLEVEGLSNLSTKTVEVLSLQKQLENRRELEKVKKRRQERELERQVREDDLMMQQRAKEAVQFREWQRQEDQFHLEQARLRSEIRIRDGRAKPIDLLAQYVAAGNEPLEECLEMQMHEPYVLLNGLPVEELEDLLVDIKVYE-ELEQGKHIDFWNDMITIVQDELQRQQKLEAENSSLNQRRDGIHQAVVKDVAD-IFRGKNAQQLEEMRHRIEAKISGRADGVDISYWESLLSQLKAHMARARLRDRHQALLREKLSLLKRENDNETLQEKVAPQVKEEEMETQDAEDPEVEEGSPEDEEDPLNELRKTVRLYQAGNYSPRYIREEDFTGRRAQNEDVDEPEAEGLLYEEEDDERRTQ--RQRLLILHPERVDNNQLTPQELRMRNEAKQGMQGDEAEFSVETTLDAVPQLATDKYRPRKPRYFNRVHTGFEWNKYNQTHYDMDNPPPKIVQGYKFNIFYPDLMDKSQTPQYFLTPCADNGDFAVLRFHTGPPYEDIAFKIVNREWEFSYKRGFRCQFHNNIFQLWFHFKRYRYRR 720

[Close]

BLAST of Cactin, spliceosome C complex subunit vs. Ensembl Zebrafish
Match: cactin (cactin [Source:NCBI gene;Acc:100126813])

HSP 1 Score: 351.288 bits (900), Expect = 1.551e-109
Identity = 231/597 (38.69%), Postives = 323/597 (54.10%), Query Frame = 3

Query:  213 CGYTDDNNPFMDPNLTKEFVWKK-----------------KNNPVQLNCQEKQAELENVQXXXXXXXXXXXXXXXXXXXXXXAKEAQNFRG-RKSDSNFDIEQAKNRSKIRIAEGRAKPIDLLIQYVNEEENTINDNADAIIHEPTQFLVGLSKXXXXXXXXXIHEYSRNMEPGKNTQYWEDIRLITEDELKRVIKTEDDG-----RTEGVTKECVDDMKQMILQGTIDESTELLNDAKKMLETGDRRHIDVAYYEYFCSLARVLIAKKRLQERHSNNLRIKLNRLKHEQGLPIEPLFP---------SAIKPEAQVDTKPTSSKKPEQKLEREEYDHSRYSPVLLSGEEL-----------------------GDEAI---ENVIYLA----DDDEKKLEFMRKKFIKFGSHKINQEDELIKLV------------------------QEGDEKGDLDFSEQIAIEEQSFLWSDKYRPRKPRFLNRVNTGFDWNKYNQTHYDMDNPPPKIVQGYKFNILYPDLIDKTKTPTFELTPCIDDDQYAMITFKAGPPYEDIAFKIVNREWETSERHGYKCQFYRDMLQLYFHFKRYRYRK 1745
             GYT+ +NPF D NL   F+W+K                 +N  +Q   +E + EL+ V++   E ER +  R  E E++QR KEA++F+   + + NF + QAK RSKIRI +GRAKPIDLL +Y++ E    +D+    +HEP  FL GL+  D++DLL DI  Y   +E GKN  +W D+  ITEDE+ ++ K E  G     R EG+      D++ +    T  +   L  + +  ++ G   ++D+ Y+E      RV +A+ RL+ERH + LR KL +LK EQG+  EPLFP           I  EA    +   S   +   E +E   SR +     GEE                          EA+   E++I  +    D        ++   +   +H I +E++L +L+                        +EG    +  FS ++ +  + +LW+DKYRPRKPRF NRV+TGF+WNKYNQTHYD DNPPPKIVQGYKFNI YPDLIDK  TP + L PC D+  + ++ F AGPPYEDIAFKIVNREWE S RHG++CQF   + QL+FHFKRYRYR+
Sbjct:  252 MGYTNADNPFGDNNLLGTFIWQKALEKKGIGHLSEKNLKDRNKHIQ---EENRRELQKVKQLRLEREREKAMREQELEMLQREKEAEHFKTWAEQEDNFHLHQAKLRSKIRIRDGRAKPIDLLAKYISAE----DDDLSVEMHEPYTFLNGLTVTDMEDLLEDIKVYM-ELECGKNVDFWRDMTTITEDEISKLRKLEASGKGPGDRREGINTSVSTDVQSVFKGKTYSQLQALYMNIESKIQAGGS-NLDIGYWESLLQQVRVYMARARLRERHQDVLRQKLYKLKQEQGVESEPLFPIIKEEPEKEQPISREAGSGEEEAGSSSQQADREEDEDRRSRRT----GGEEAERSGRSSPEEEKKGEEEEGEKDEAPEAVLTEEDLIQQSQAEYDSGRYSPTLLQNSELPLDTHIIAEEEDLQRLLLARRQMQVTGDASESAEDLFVRRAKEGMGGDEAQFSVEMPLTGKMYLWADKYRPRKPRFFNRVHTGFEWNKYNQTHYDFDNPPPKIVQGYKFNIFYPDLIDKRSTPQYFLEPCPDNKDFGILRFHAGPPYEDIAFKIVNREWEYSHRHGFRCQFANGIFQLWFHFKRYRYRR 835

[Close]

BLAST of Cactin, spliceosome C complex subunit vs. Ensembl Zebrafish
Match: cactin (cactin [Source:NCBI gene;Acc:100126813])

HSP 1 Score: 83.5741 bits (205), Expect = 4.438e-18
Identity = 46/129 (35.66%), Postives = 71/129 (55.04%), Query Frame = 3

Query:  669 MEPGKNTQYWEDIRLITEDELKRVIKTEDDG-----RTEGVTKECVDDMKQMILQGTIDESTELLNDAKKMLETGDRRHIDVAYYEYFCSLARVLIAKKRLQERHSNNLRIKLNRLKHEQGLPIEPLFP 1040
            +E GKN  +W D+  ITEDE+ ++ K E  G     R EG+      D++ +    T  +   L  + +  ++ G   ++D+ Y+E      RV +A+ RL+ERH + LR KL +LK EQG+  EPLFP
Sbjct:   14 LECGKNVDFWRDMTTITEDEISKLRKLEASGKGPGDRREGINTSVSTDVQSVFKGKTYSQLQALYMNIESKIQAGGS-NLDIGYWESLLQQVRVYMARARLRERHQDVLRQKLYKLKQEQGVESEPLFP 141

[Close]

BLAST of Cactin, spliceosome C complex subunit vs. Ensembl Xenopus
Match: CACTIN (cactin, spliceosome C complex subunit [Source:NCBI gene;Acc:100487223])

HSP 1 Score: 382.874 bits (982), Expect = 7.592e-122
Identity = 240/572 (41.96%), Postives = 335/572 (58.57%), Query Frame = 3

Query:  216 GYTDDNNPFMDPNLTKEFVW-----------------KKKNNPVQLNCQEKQAELENVQXXXXXXXXXXXXXXXXXXXXXXAKEAQNFRG-RKSDSNFDIEQAKNRSKIRIAEGRAKPIDLLIQYVNEEENTINDNADAIIHEPTQFLVGLSKXXXXXXXXXIHEYSRNMEPGKNTQYWEDIRLITEDELKRVIKTEDDG-----RTEGVTKECVDDMKQMILQGTIDESTELLNDAKKMLETGDRRHIDVAYYEYFCSLARVLIAKKRLQERHSNNLRIKLNRLKHEQGLPIEPLFPSAIKPEAQV------DTKPTSSKKP----------EQKLEREE-----------------------YDHSRYSPVLLSGEELGDEAIENVIYLADDDEKKLEFMRKKFIKFGSHKINQEDELIKLVQEGDEKGDLDFSEQIAIEEQSFLWSDKYRPRKPRFLNRVNTGFDWNKYNQTHYDMDNPPPKIVQGYKFNILYPDLIDKTKTPTFELTPCIDDDQYAMITFKAGPPYEDIAFKIVNREWETSERHGYKCQFYRDMLQLYFHFKRYRYRK 1745
            GYT+ +NPF D NL   F+W                 K++N  +Q   ++ + EL+ V++   E ER +  R  E E++QR KEA++F+   + + NF ++QAK RSKIRI +GRAKPIDLL +Y++ E    +D+    +HEP  FL GL+  DL+DLL DI  Y   +E GKN  +W D+ +ITEDE+ ++ K E  G     R EGV      D++ +    T ++   +    +  + TG   ++D+ Y+E      R  +A+ RL+ERH + LR KL +LK EQG+  EPLFP  IKPE +       + +P S + P          E  +E EE                       YD  RYSP LL+ +EL  +A  +V+   +D ++ +   R++    G    + ED  I+  +EG +  +  FS +I +  +++LW+DKYRPRKPRF NRV+TGF+WNKYNQTHYD DNPPPKIVQGYKFNI YPDLIDK  TP + L  C D+  +A++ F AGPPYEDIAFKIVNREWE S RHG++CQF   + QL+FHFKRYRYR+
Sbjct:  239 GYTNTDNPFGDNNLLGTFIWNKALEKKGIGHLTEKDLKERNKHIQ---EDNRLELQKVKQLRLEREREKAMREQELEMLQREKEAEHFKTWEEQEDNFHLQQAKLRSKIRIRDGRAKPIDLLAKYISAE----DDDLAVEMHEPYTFLNGLTVSDLEDLLEDIQIYM-ELEQGKNVDFWRDMTVITEDEISKLRKLEFSGKGPGERREGVNASVSTDVQTVFKGKTYNQLQAISQGIESRIRTGGP-NLDIGYWESLLQQLRAYMARARLRERHQDVLRQKLFKLKQEQGVESEPLFP-IIKPEPESPSNRESEVEPLSGQPPSSTSAAPEESESAIEGEEKNEAEGGESVLMEEDLIQQSLNDYDAGRYSPKLLTVQELPFDA--HVVDFEEDQQRTV-LCRQQLQVTGDASESPEDIFIRKAKEGMDGDEAQFSVEIPVTSKAYLWADKYRPRKPRFFNRVHTGFEWNKYNQTHYDFDNPPPKIVQGYKFNIFYPDLIDKRSTPEYFLEACHDNKDFAILRFHAGPPYEDIAFKIVNREWEYSHRHGFRCQFSNGIFQLWFHFKRYRYRR 797

[Close]

BLAST of Cactin, spliceosome C complex subunit vs. Ensembl Mouse
Match: Cactin (cactin, spliceosome C complex subunit [Source:MGI Symbol;Acc:MGI:1917562])

HSP 1 Score: 365.54 bits (937), Expect = 1.403e-115
Identity = 229/572 (40.03%), Postives = 324/572 (56.64%), Query Frame = 3

Query:  213 CGYTDDNNPFMDPNLTKEFVW-----------------KKKNNPVQLNCQEKQAELENVQXXXXXXXXXXXXXXXXXXXXXXAKEAQNFRG-RKSDSNFDIEQAKNRSKIRIAEGRAKPIDLLIQYVNEEENTINDNADAIIHEPTQFLVGLSKXXXXXXXXXIHEYSRNMEPGKNTQYWEDIRLITEDELKRVIKTEDDG-----RTEGVTKECVDDMKQMILQGTIDESTELLNDAKKMLETGDRRHIDVAYYEYFCSLARVLIAKKRLQERHSNNLRIKLNRLKHEQGLPIEPLFPSAIKPEAQV---------DTKPTSSKKPEQKLEREE-----------------------------YDHSRYSPVLLSGEELGDEAIENVIYLADDDEKKLEFMRKKFIKFGSHKINQEDELIKLVQEGDEKGDLDFSEQIAIEEQSFLWSDKYRPRKPRFLNRVNTGFDWNKYNQTHYDMDNPPPKIVQGYKFNILYPDLIDKTKTPTFELTPCIDDDQYAMITFKAGPPYEDIAFKIVNREWETSERHGYKCQFYRDMLQLYFHFKRYRYRK 1745
             GYT+ +NPF D NL   F+W                 K++N  +Q   ++ + EL+ V++   E ER +  R  E E++QR KEA++F+   + + +F + QAK RSKIRI +GRAKPIDLL +Y++ E    +D+    +HEP  FL GL+  D++DLL DI  Y   +E GKN  +W D+  ITEDE+ ++ K E  G     R EGV      D++ +    T ++   +    +  +  G   ++D+ Y+E      R  +A+ RL+ERH + LR KL +LK EQG+  EPLFP  +K E               P +S  P + +E EE                             YD  RYSP LL+  EL    ++  +    +D ++L+  R++    G    + ED   +  +EG  + +  FS ++ +  +++LW+DKYRPRKPRF NRV+TGF+WNKYNQTHYD DNPPPKIVQGYKFNI YPDLI K  TP + L  C D+  +A++ F AGPPYEDIAFKIV+REWE S RHG++CQF   + QL+FHFKRYRYR+
Sbjct:  214 MGYTNTDNPFGDNNLLGTFIWNKALEKKGISHLEEKELKERNKRIQ---EDNRLELQKVKQLRLEREREKAMREQELELLQREKEAEHFKTWEEQEDSFHLRQAKLRSKIRIRDGRAKPIDLLAKYISAE----DDDLAVEMHEPYTFLNGLTVADMEDLLEDIQVYM-ELEQGKNVDFWRDMTTITEDEIAKLRKLEASGKGPGERREGVNASVSSDVQSVFKGKTYNQLQVIFQGIEGKIRAGGP-NLDMGYWESLLQQLRAHMARARLRERHQDVLRQKLFKLKQEQGVESEPLFP-ILKSEPSAAHSPEPEERPPSPGTSVDPVEPVEPEEATAPGEAEGEAEGEAVLMEEDLIQQSLADYDAGRYSPRLLTAHEL---PLDAHVLEPHEDLQRLQLSRQQLQATGDASESAEDIFFRRAREGMGQDEAQFSVEMPLGGRAYLWADKYRPRKPRFFNRVHTGFEWNKYNQTHYDFDNPPPKIVQGYKFNIFYPDLIRKRATPEYFLEACADNRDFAILRFHAGPPYEDIAFKIVSREWEYSHRHGFRCQFANGIFQLWFHFKRYRYRR 772

[Close]

BLAST of Cactin, spliceosome C complex subunit vs. Ensembl Mouse
Match: Cactin (cactin, spliceosome C complex subunit [Source:MGI Symbol;Acc:MGI:1917562])

HSP 1 Score: 114.775 bits (286), Expect = 1.939e-28
Identity = 76/192 (39.58%), Postives = 110/192 (57.29%), Query Frame = 3

Query:  480 SKIRIAEGRAKPIDLLIQYVNEEENTINDNADAIIHEPTQFLVGLSKXXXXXXXXXIHEYSRNMEPGKNTQYWEDIRLITEDELKRVIKTEDDG-----RTEGVTKECVDDMKQMILQGTIDESTELLNDAKKMLETGDRRHIDVAYYEYFCSLARVLIAKKRLQERHSNNLRIKLNRLKHEQGLPIEPLFP 1040
            SKIRI +GRAKPIDLL +Y++ E    +D+    +HEP  FL GL+  D++DLL DI  Y   +E GKN  +W D+  ITEDE+ ++ K E  G     R EGV      D++ +    T ++   +    +  +  G   ++D+ Y+E      R  +A+ RL+ERH + LR KL +LK EQG+  EPLFP
Sbjct:    4 SKIRIRDGRAKPIDLLAKYISAE----DDDLAVEMHEPYTFLNGLTVADMEDLLEDIQVYM-ELEQGKNVDFWRDMTTITEDEIAKLRKLEASGKGPGERREGVNASVSSDVQSVFKGKTYNQLQVIFQGIEGKIRAGGP-NLDMGYWESLLQQLRAHMARARLRERHQDVLRQKLFKLKQEQGVESEPLFP 189

[Close]

BLAST of Cactin, spliceosome C complex subunit vs. UniProt/SwissProt
Match: sp|Q8WUQ7|CATIN_HUMAN (Cactin OS=Homo sapiens OX=9606 GN=CACTIN PE=1 SV=3)

HSP 1 Score: 375.941 bits (964), Expect = 6.150e-119
Identity = 232/581 (39.93%), Postives = 329/581 (56.63%), Query Frame = 3

Query:  213 CGYTDDNNPFMDPNLTKEFVW-----------------KKKNNPVQLNCQEKQAELENVQXXXXXXXXXXXXXXXXXXXXXXAKEAQNFRG-RKSDSNFDIEQAKNRSKIRIAEGRAKPIDLLIQYVNEEENTINDNADAIIHEPTQFLVGLSKXXXXXXXXXIHEYSRNMEPGKNTQYWEDIRLITEDELKRVIKTEDDG-----RTEGVTKECVDDMKQMILQGTIDESTELLNDAKKMLETGDRRHIDVAYYEYFCSLARVLIAKKRLQERHSNNLRIKLNRLKHEQGLPIEPLFP----------SAIKPEAQVDTKPTSSKKP-------------------------------------EQKLEREEYDHSRYSPVLLSGEELGDEAIENVIYLADDDEKKLEFMRKKFIKFGSHKINQEDELIKLVQEGDEKGDLDFSEQIAIEEQSFLWSDKYRPRKPRFLNRVNTGFDWNKYNQTHYDMDNPPPKIVQGYKFNILYPDLIDKTKTPTFELTPCIDDDQYAMITFKAGPPYEDIAFKIVNREWETSERHGYKCQFYRDMLQLYFHFKRYRYRK 1745
             GYT+ +NPF D NL   F+W                 K++N  +Q   ++ + EL+ V++   E ER +  R  E E++QR KEA++F+   + + NF ++QAK RSKIRI +GRAKPIDLL +Y++ E    +D+    +HEP  FL GL+  D++DLL DI  Y   +E GKN  +W D+  ITEDE+ ++ K E  G     R EGV      D++ +    T ++   +    +  +  G   ++D+ Y+E      R  +A+ RL+ERH + LR KL +LK EQG+  EPLFP           +++PE    T P  S +                                      +Q L+  +YD  RYSP LL+  EL    ++  +   D+D ++L+  R++    G    + ED   +  +EG  + +  FS ++ +  +++LW+DKYRPRKPRF NRV+TGF+WNKYNQTHYD DNPPPKIVQGYKFNI YPDLIDK  TP + L  C D+  +A++ F AGPPYEDIAFKIVNREWE S RHG++CQF   + QL+FHFKRYRYR+
Sbjct:  192 MGYTNTDNPFGDNNLLGTFIWNKALEKKGISHLEEKELKERNKRIQ---EDNRLELQKVKQLRLEREREKAMREQELEMLQREKEAEHFKTWEEQEDNFHLQQAKLRSKIRIRDGRAKPIDLLAKYISAE----DDDLAVEMHEPYTFLNGLTVADMEDLLEDIQVYM-ELEQGKNADFWRDMTTITEDEISKLRKLEASGKGPGERREGVNASVSSDVQSVFKGKTYNQLQVIFQGIEGKIRAGGP-NLDMGYWESLLQQLRAHMARARLRERHQDVLRQKLYKLKQEQGVESEPLFPILKQEPQSPSRSLEPEDAAPTPPGPSSEGGPAEAEVDGATPTEGDGDGDGEGEGEGEAVLMEEDLIQQSLD--DYDAGRYSPRLLTAHEL---PLDAHVLEPDEDLQRLQLSRQQLQVTGDASESAEDIFFRRAKEGMGQDEAQFSVEMPLTGKAYLWADKYRPRKPRFFNRVHTGFEWNKYNQTHYDFDNPPPKIVQGYKFNIFYPDLIDKRSTPEYFLEACADNKDFAILRFHAGPPYEDIAFKIVNREWEYSHRHGFRCQFANGIFQLWFHFKRYRYRR 758

[Close]

BLAST of Cactin, spliceosome C complex subunit vs. UniProt/SwissProt
Match: sp|Q9CS00|CATIN_MOUSE (Cactin OS=Mus musculus OX=10090 GN=Cactin PE=1 SV=2)

HSP 1 Score: 365.54 bits (937), Expect = 9.813e-115
Identity = 229/572 (40.03%), Postives = 324/572 (56.64%), Query Frame = 3

Query:  213 CGYTDDNNPFMDPNLTKEFVW-----------------KKKNNPVQLNCQEKQAELENVQXXXXXXXXXXXXXXXXXXXXXXAKEAQNFRG-RKSDSNFDIEQAKNRSKIRIAEGRAKPIDLLIQYVNEEENTINDNADAIIHEPTQFLVGLSKXXXXXXXXXIHEYSRNMEPGKNTQYWEDIRLITEDELKRVIKTEDDG-----RTEGVTKECVDDMKQMILQGTIDESTELLNDAKKMLETGDRRHIDVAYYEYFCSLARVLIAKKRLQERHSNNLRIKLNRLKHEQGLPIEPLFPSAIKPEAQV---------DTKPTSSKKPEQKLEREE-----------------------------YDHSRYSPVLLSGEELGDEAIENVIYLADDDEKKLEFMRKKFIKFGSHKINQEDELIKLVQEGDEKGDLDFSEQIAIEEQSFLWSDKYRPRKPRFLNRVNTGFDWNKYNQTHYDMDNPPPKIVQGYKFNILYPDLIDKTKTPTFELTPCIDDDQYAMITFKAGPPYEDIAFKIVNREWETSERHGYKCQFYRDMLQLYFHFKRYRYRK 1745
             GYT+ +NPF D NL   F+W                 K++N  +Q   ++ + EL+ V++   E ER +  R  E E++QR KEA++F+   + + +F + QAK RSKIRI +GRAKPIDLL +Y++ E    +D+    +HEP  FL GL+  D++DLL DI  Y   +E GKN  +W D+  ITEDE+ ++ K E  G     R EGV      D++ +    T ++   +    +  +  G   ++D+ Y+E      R  +A+ RL+ERH + LR KL +LK EQG+  EPLFP  +K E               P +S  P + +E EE                             YD  RYSP LL+  EL    ++  +    +D ++L+  R++    G    + ED   +  +EG  + +  FS ++ +  +++LW+DKYRPRKPRF NRV+TGF+WNKYNQTHYD DNPPPKIVQGYKFNI YPDLI K  TP + L  C D+  +A++ F AGPPYEDIAFKIV+REWE S RHG++CQF   + QL+FHFKRYRYR+
Sbjct:  214 MGYTNTDNPFGDNNLLGTFIWNKALEKKGISHLEEKELKERNKRIQ---EDNRLELQKVKQLRLEREREKAMREQELELLQREKEAEHFKTWEEQEDSFHLRQAKLRSKIRIRDGRAKPIDLLAKYISAE----DDDLAVEMHEPYTFLNGLTVADMEDLLEDIQVYM-ELEQGKNVDFWRDMTTITEDEIAKLRKLEASGKGPGERREGVNASVSSDVQSVFKGKTYNQLQVIFQGIEGKIRAGGP-NLDMGYWESLLQQLRAHMARARLRERHQDVLRQKLFKLKQEQGVESEPLFP-ILKSEPSAAHSPEPEERPPSPGTSVDPVEPVEPEEATAPGEAEGEAEGEAVLMEEDLIQQSLADYDAGRYSPRLLTAHEL---PLDAHVLEPHEDLQRLQLSRQQLQATGDASESAEDIFFRRAREGMGQDEAQFSVEMPLGGRAYLWADKYRPRKPRFFNRVHTGFEWNKYNQTHYDFDNPPPKIVQGYKFNIFYPDLIRKRATPEYFLEACADNRDFAILRFHAGPPYEDIAFKIVSREWEYSHRHGFRCQFANGIFQLWFHFKRYRYRR 772

[Close]

BLAST of Cactin, spliceosome C complex subunit vs. UniProt/SwissProt
Match: sp|F1Q8W0|CATIN_DANRE (Cactin OS=Danio rerio OX=7955 GN=cactin PE=2 SV=1)

HSP 1 Score: 351.288 bits (900), Expect = 1.170e-108
Identity = 231/597 (38.69%), Postives = 323/597 (54.10%), Query Frame = 3

Query:  213 CGYTDDNNPFMDPNLTKEFVWKK-----------------KNNPVQLNCQEKQAELENVQXXXXXXXXXXXXXXXXXXXXXXAKEAQNFRG-RKSDSNFDIEQAKNRSKIRIAEGRAKPIDLLIQYVNEEENTINDNADAIIHEPTQFLVGLSKXXXXXXXXXIHEYSRNMEPGKNTQYWEDIRLITEDELKRVIKTEDDG-----RTEGVTKECVDDMKQMILQGTIDESTELLNDAKKMLETGDRRHIDVAYYEYFCSLARVLIAKKRLQERHSNNLRIKLNRLKHEQGLPIEPLFP---------SAIKPEAQVDTKPTSSKKPEQKLEREEYDHSRYSPVLLSGEEL-----------------------GDEAI---ENVIYLA----DDDEKKLEFMRKKFIKFGSHKINQEDELIKLV------------------------QEGDEKGDLDFSEQIAIEEQSFLWSDKYRPRKPRFLNRVNTGFDWNKYNQTHYDMDNPPPKIVQGYKFNILYPDLIDKTKTPTFELTPCIDDDQYAMITFKAGPPYEDIAFKIVNREWETSERHGYKCQFYRDMLQLYFHFKRYRYRK 1745
             GYT+ +NPF D NL   F+W+K                 +N  +Q   +E + EL+ V++   E ER +  R  E E++QR KEA++F+   + + NF + QAK RSKIRI +GRAKPIDLL +Y++ E    +D+    +HEP  FL GL+  D++DLL DI  Y   +E GKN  +W D+  ITEDE+ ++ K E  G     R EG+      D++ +    T  +   L  + +  ++ G   ++D+ Y+E      RV +A+ RL+ERH + LR KL +LK EQG+  EPLFP           I  EA    +   S   +   E +E   SR +     GEE                          EA+   E++I  +    D        ++   +   +H I +E++L +L+                        +EG    +  FS ++ +  + +LW+DKYRPRKPRF NRV+TGF+WNKYNQTHYD DNPPPKIVQGYKFNI YPDLIDK  TP + L PC D+  + ++ F AGPPYEDIAFKIVNREWE S RHG++CQF   + QL+FHFKRYRYR+
Sbjct:  252 MGYTNADNPFGDNNLLGTFIWQKALEKKGIGHLSEKNLKDRNKHIQ---EENRRELQKVKQLRLEREREKAMREQELEMLQREKEAEHFKTWAEQEDNFHLHQAKLRSKIRIRDGRAKPIDLLAKYISAE----DDDLSVEMHEPYTFLNGLTVTDMEDLLEDIKVYM-ELECGKNVDFWRDMTTITEDEISKLRKLEASGKGPGDRREGINTSVSTDVQSVFKGKTYSQLQALYMNIESKIQAGGS-NLDIGYWESLLQQVRVYMARARLRERHQDVLRQKLYKLKQEQGVESEPLFPIIKEEPEKEQPISREAGSGEEEAGSSSQQADREEDEDRRSRRT----GGEEAERSGRSSPEEEKKGEEEEGEKDEAPEAVLTEEDLIQQSQAEYDSGRYSPTLLQNSELPLDTHIIAEEEDLQRLLLARRQMQVTGDASESAEDLFVRRAKEGMGGDEAQFSVEMPLTGKMYLWADKYRPRKPRFFNRVHTGFEWNKYNQTHYDFDNPPPKIVQGYKFNIFYPDLIDKRSTPQYFLEPCPDNKDFGILRFHAGPPYEDIAFKIVNREWEYSHRHGFRCQFANGIFQLWFHFKRYRYRR 835

[Close]

BLAST of Cactin, spliceosome C complex subunit vs. UniProt/SwissProt
Match: sp|Q9VR99|CATIN_DROME (Cactin OS=Drosophila melanogaster OX=7227 GN=cactin PE=1 SV=3)

HSP 1 Score: 327.791 bits (839), Expect = 5.853e-101
Identity = 215/558 (38.53%), Postives = 319/558 (57.17%), Query Frame = 3

Query:  219 YTDDNNPFMDPNLTKEFVWKKK----------NNPVQLNCQEKQAE----LENVQXXXXXXXXXXXXXXXXXXXXXXAKEAQNFR-GRKSDSNFDIEQAKNRSKIRIAEGRAKPIDLLIQYVNEEENTINDNADAIIHEPTQFLVGLSKXXXXXXXXXIHEYSRNMEPGKNTQYWEDIRLITEDELKRVIKTEDDG-----RTEGVTKECVDDMKQMILQGTIDESTELLNDAKKMLETGDRRHIDVAYYEYFCSLARVLIAKKRLQERHSNNLRIKLNRLKHEQGLPI--EPLFPSAIKPEAQV---------DTKPTSSKKPEQKLER--EEYDHSRYSPVLL----------SGEELGDEAIENVIYLADDDEKKLEFMRKKFIKFGSHKIN------QEDELIKLVQEGDEKGDLDFSEQIAIEEQSFLWSDKYRPRKPRFLNRVNTGFDWNKYNQTHYDMDNPPPKIVQGYKFNILYPDLIDKTKTPTFELTPCIDDDQYAMITFKAGPPYEDIAFKIVNREWETSERHGYKCQFYRDMLQLYFHFKRYRYRK 1745
            Y++++NPF D NLT  F W KK             V++   +KQ E    LE V++R +E E  R+ R  +  + QRAKEA  FR  ++ +  F +EQA+ RS+IRI +GRAKPIDLL QYV      + +  +  +HEP   L GL   +L+DLLVDI  Y   +E GK+  +W D+  I +DEL+R  K E +      R +G+ +  V D+   I +G   +  E +    +   +G    +D++Y+E   S  +  +A+ RL++RH   LR KL+ LK E       E + P   + E +          +  P   + P  +L +    Y    YSP  +            E++ +   E ++Y  +DDE++ +  R++ +     +++      QE  +    ++G +  + +FS +  ++    L +DKYRPRKPR+ NRV+TGF+WNKYNQTHYDMDNPPPKIVQGYKFNI YPDL+DK++TP + LTPC D+  +A++ F  GPPYEDIAFKIVNREWE S + G++CQF+ ++ QL+FHFKRYRYR+
Sbjct:  167 YSNEDNPFGDSNLTSTFHWGKKLEVEGLSNLSTKTVEVLSLQKQLENRRELEKVKKRRQERELERQVREDDLMMQQRAKEAVQFREWQRQEDQFHLEQARLRSEIRIRDGRAKPIDLLAQYVAAGNEPLEECLEMQMHEPYVLLNGLPVEELEDLLVDIKVYE-ELEQGKHIDFWNDMITIVQDELQRQQKLEAENSSLNQRRDGIHQAVVKDVAD-IFRGKNAQQLEEMRHRIEAKISGRADGVDISYWESLLSQLKAHMARARLRDRHQALLREKLSLLKRENDNETLQEKVAPQVKEEEMETQDAEDPEVEEGSPEDEEDPLNELRKTVRLYQAGNYSPRYIREEDFTGRRAQNEDVDEPEAEGLLYEEEDDERRTQ--RQRLLILHPERVDNNQLTPQELRMRNEAKQGMQGDEAEFSVETTLDAVPQLATDKYRPRKPRYFNRVHTGFEWNKYNQTHYDMDNPPPKIVQGYKFNIFYPDLMDKSQTPQYFLTPCADNGDFAVLRFHTGPPYEDIAFKIVNREWEFSYKRGFRCQFHNNIFQLWFHFKRYRYRR 720

[Close]

BLAST of Cactin, spliceosome C complex subunit vs. UniProt/SwissProt
Match: sp|G5EG14|CATIN_CAEEL (Cactin OS=Caenorhabditis elegans OX=6239 GN=cacn-1 PE=1 SV=1)

HSP 1 Score: 275.789 bits (704), Expect = 6.562e-82
Identity = 204/580 (35.17%), Postives = 286/580 (49.31%), Query Frame = 3

Query:  219 YTDDNNPFMDPNLTKEFVWKKKN--------NPVQLNCQEKQAELENVQXXXXXXXXXXXXXXXXXXXXXXAKEAQNFRGRKSDSN---FDIEQAKNRSKIRIAEGRAKPIDLLIQYVN--EEENTINDNADAIIHEPTQFLVGLSKXXX--XXXXXXIHEYSRNMEPGKNTQYWEDIRLITEDEL-KRVIKTEDDGRTEGVTKECVDDMKQMILQGTIDESTELLN--DAKKMLETGDRRHIDVAYYEYFCSLARVLIAKKRLQERHSNNLRIKLNRLKHEQGLPI-----EPLFPSA-IKPEAQVDTKPTS-----------SKKPEQKLE------------------------------REEYDHSRYSPVLLS------GEELGDEAIENVIYLADDDEKKLEFMRKKFIKFGSHKINQEDELIKLVQEGDEKGDLDFSEQIAIEEQSFLWSDKYRPRKPRFLNRVNTGFDWNKYNQTHYDMDNPPPKIVQGYKFNILYPDLIDKTKTPTFELTPCIDDDQYAMITFKAGPPYEDIAFKIVNREWETSERHGYKCQFYRDMLQLYFHFKRYRYRK 1745
            YT+ NNPF D  LT+ FVW KK            ++  Q  Q   +N+    +           ++++    ++A    G+ SD+    F ++Q K R++IRI +GRAK IDLL +Y    +E        D  +  P ++L    K     +DL+ DI  Y       KN  +W D+  I EDE+ K+  +   D     V      +++ M    +IDE  +L +  DAK    +G++      Y++      +V IA+KRL+E H   LR++L  +K EQ   I     E L P A + P+ ++  +              SKK  +K++                              RE Y    YSP  +S      G E+ DE   +V  L +   +    +                +++ + +EG E  +  F  +  +  Q  LWSDKYRPRKP +LNRV TGFDWNKYNQTHYD DNPPPKIVQGYKFNI YPDL+D T  P F LT C D D +A+I FKAGPPYEDIAFK+VNREWET  ++GYKCQF   + QL+F FK+YRYR+
Sbjct:   90 YTNLNNPFNDTKLTQTFVWGKKLEREGKSGLTQDEITKQTSQRIRKNLHEAAEFKRIRDSRAAAKEDMEMMKRDADLRAGQISDTKEREFQMDQIKERTRIRIDQGRAKAIDLLSRYARFADENPHTAKIPDFELENPMEYLKASCKSVDDYEDLIEDIKTYREVDGWAKNETWWMDVTRIAEDEIQKKAAQNRGD-----VHASVQTEVQNMFKNKSIDELLKLEDQMDAKIRGNSGNK-----GYWQDLDDQLKVFIARKRLREHHGRVLRLQLAIIKEEQKKEIQQQESEELLPVAEVPPQVKIQKEEEEEEEEDEDDEKISKKVRRKIDVQTLDDPELDEPERERKWRALTGDQLDDVTRELYRIGCYSPTYISADDTMPGIEILDEQA-DVDNLTERRNRNRGTLPSSSAASSGAPQGASSKMMAIAREGMEADESIFGAEEQLAAQRHLWSDKYRPRKPTYLNRVQTGFDWNKYNQTHYDQDNPPPKIVQGYKFNIFYPDLLDMTVAPRFGLTSCEDPD-FAIIRFKAGPPYEDIAFKVVNREWETLHKNGYKCQFQNGVFQLWFMFKKYRYRR 657

[Close]

BLAST of Cactin, spliceosome C complex subunit vs. TrEMBL
Match: A0A4S2LMZ6 (Uncharacterized protein OS=Opisthorchis felineus OX=147828 GN=CRM22_006385 PE=4 SV=1)

HSP 1 Score: 410.994 bits (1055), Expect = 8.646e-130
Identity = 259/592 (43.75%), Postives = 353/592 (59.63%), Query Frame = 3

Query:  213 CGYTDDNNPFMDPNLTKEFVWKKKNNPVQLN--------------CQEKQAELENVQXXXXXXXXXXXXXXXXXXXXXXAKEAQNFR--GRKSDSNFDIEQAKNRSKIRIAEGRAKPIDLLIQYVNEEENTINDNAD--AIIH--EPTQFLVGLSKXXXXXXXXXIHEYSRNMEPGKNTQYWEDIRLITEDELKRVIKTEDD-------------GRTEGVTKECVDDMKQMILQG-TIDESTELLNDAKKMLETGDRRHIDVAYYEYFCSLARVLIAKKRLQERHSNNLRIKLNRLKHEQGLPIEPLFPSAI-----------------------------KPEAQVDTKP---------------TSSKKPEQKLEREEYDHSRYSPVLLSGEELGDEAIENVIYLADDDEKKLEFMRKKFIKFGSHKINQEDELIKLVQEGDEKG-DLDFSEQIAIEEQSFLWSDKYRPRKPRFLNRVNTGFDWNKYNQTHYDMDNPPPKIVQGYKFNILYPDLIDKTKTPTFELTPCIDDDQ--YAMITFKAGPPYEDIAFKIVNREWETSERHGYKCQFYRDMLQLYFHFKRYRYRK 1745
             GYT+++NPF D  L++ FVWK+K     L                +E + ELE+V+RR  E ER REER  E E+MQR KEA+ +R  G++ D+ F +EQAK RS+IRIA+GRAKPIDLL +Y+ ++E     +A+   +I   EPTQFLVGLS  DL+DLL DI      +E G+N +YW DI  + EDEL ++ + E+D             GR+     + V       L+G T ++   L    +  L+ G+   +DV Y+E      R  +A+ RL++ H  NLR KL  L+  QG+  EPLFPS                               +PE   DT+P                +  +    +E E YD + YSP  +   E+   A++ VIY  +DD  K+++ RK  ++ G+ + ++E+EL++  +EG E G D  FS QI +E+QSFLWSDKYRPRKPRF NRV+TGF WNKYNQTHYD+DNPPPK+VQGYKFN+ YPDLIDK+KTPT+ LTPC D  Q  +A++ F AGPPYEDIAFKIVNREWE S +HG++CQF  ++ QL+FHFKR+RYR+
Sbjct:  181 LGYTNEDNPFGDHRLSESFVWKQKLEAEGLTHLSKEEIQELQKKKMEENKLELESVRRRRAEREREREEREKEMEMMQRDKEAEYYRSWGQQEDT-FHLEQAKLRSRIRIADGRAKPIDLLAKYIADQEEDAMASAEFTGVIELLEPTQFLVGLSVEDLEDLLEDIKVVYMQLEKGRNAEYWRDITTVAEDELNKLRRAENDSAGLAAAYGADSRGRSSASISQSVMQSVAETLKGKTYNQLAALERQIEPKLKGGE--GVDVTYWETLAQFVRAQMARTRLRDMHQENLRRKLECLRQSQGIVQEPLFPSGTDQPQPSTSQMVRSDTQLMPPPAIDKLRGEEPEEPEDTQPQIEDPHSAEAIRAARQAQLEAAAMVEEEMYDAACYSPPRVDPTEV---ALDAVIYNPEDDRAKIDYQRKDVLRTGAMRASEEEELMRRAREGMEDGEDAQFSVQIPLEDQSFLWSDKYRPRKPRFFNRVHTGFVWNKYNQTHYDLDNPPPKVVQGYKFNVFYPDLIDKSKTPTYTLTPCEDPSQRDFAILRFSAGPPYEDIAFKIVNREWEYSYKHGFRCQFQNNIFQLWFHFKRFRYRR 766

[Close]

BLAST of Cactin, spliceosome C complex subunit vs. TrEMBL
Match: A0A3R7ETC6 (Cactin OS=Clonorchis sinensis OX=79923 GN=CACTIN PE=4 SV=1)

HSP 1 Score: 413.305 bits (1061), Expect = 8.633e-129
Identity = 261/592 (44.09%), Postives = 356/592 (60.14%), Query Frame = 3

Query:  213 CGYTDDNNPFMDPNLTKEFVWKKKNNPVQLN--------------CQEKQAELENVQXXXXXXXXXXXXXXXXXXXXXXAKEAQNFR--GRKSDSNFDIEQAKNRSKIRIAEGRAKPIDLLIQYVNEEENTINDNAD--AIIH--EPTQFLVGLSKXXXXXXXXXIHEYSRNMEPGKNTQYWEDIRLITEDELKRVIKTEDD-------------GRTEGVTKECVDDMKQMILQG-TIDESTELLNDAKKMLETGDRRHIDVAYYEYFCSLARVLIAKKRLQERHSNNLRIKLNRLKHEQGLPIEPLFPSA-----------IKPEAQVDTKPTSSK-------KPEQK--------------------------LEREEYDHSRYSPVLLSGEELGDEAIENVIYLADDDEKKLEFMRKKFIKFGSHKINQEDELIKLVQEGDEKG-DLDFSEQIAIEEQSFLWSDKYRPRKPRFLNRVNTGFDWNKYNQTHYDMDNPPPKIVQGYKFNILYPDLIDKTKTPTFELTPCIDDDQ--YAMITFKAGPPYEDIAFKIVNREWETSERHGYKCQFYRDMLQLYFHFKRYRYRK 1745
             GYT+++NPF D  L++ FVWK+K     L                +E + ELE+V+RR  E ER REER  E E+MQR KEA+ +R  G++ D+ F +EQAK RS+IRIA+GRAKPIDLL +Y+ ++E     +A+   +I   EPTQFLVGLS  DL+DLLVDI      +E G+N +YW DI  + EDEL ++ + E+D             GR+     + V       L+G T ++   L    +  L+ G+   +DV Y+E      R  +A+ RL++ H  NLR KL  L+  QG+  EPLFPS            I+ + Q+   P   K       +PE                            +E E YD + YSP  +   E+   A++ VIY  +DD  K+++ RK+ ++ G+ + ++E+EL++  +EG E G D  FS QI +E+QSFLWSDKYRPRKPRF NRV+TGF WNKYNQTHYD+DNPPPK+VQGYKFN+ YPDLIDK+KTPT+ LTPC D  Q  +A++ F AGPPYEDIAFKIVNREWE S +HG++CQF  ++ QL+FHFKR+RYR+
Sbjct:  350 LGYTNEDNPFGDHRLSESFVWKQKLEAEGLTHLSKEEIQELQKKKMEENKLELESVRRRRAEREREREEREKEMEMMQRDKEAEYYRSWGQQEDT-FHLEQAKLRSRIRIADGRAKPIDLLAKYIADQEEDAMASAEFTGVIELLEPTQFLVGLSVEDLEDLLVDIKVVYMQLEKGRNAEYWRDITTVAEDELNKLRRAENDSAGLAAAYGADSRGRSSASISQSVMQSVAETLKGKTYNQLAALERQIEPKLKGGE--GVDVTYWETLAQFVRAQMARTRLRDMHQENLRRKLECLRQSQGIVQEPLFPSGTDQPQPSTSQMIRSDTQLMPPPAVDKLRGEEPDEPEDTQPQIEDPHSAEAIRAARQAQLEAAAMVEEEMYDAACYSPPRVDATEV---ALDAVIYNPEDDRAKIDYQRKEVLRTGAMRASEEEELMRRAREGMEDGEDAQFSVQIPLEDQSFLWSDKYRPRKPRFFNRVHTGFVWNKYNQTHYDLDNPPPKVVQGYKFNVFYPDLIDKSKTPTYTLTPCEDPSQRDFAILRFSAGPPYEDIAFKIVNREWEYSYKHGFRCQFQNNIFQLWFHFKRFRYRR 935

[Close]

BLAST of Cactin, spliceosome C complex subunit vs. TrEMBL
Match: A0A1S8WZG4 (Uncharacterized protein OS=Opisthorchis viverrini OX=6198 GN=X801_04245 PE=4 SV=1)

HSP 1 Score: 412.535 bits (1059), Expect = 1.492e-128
Identity = 261/591 (44.16%), Postives = 357/591 (60.41%), Query Frame = 3

Query:  216 GYTDDNNPFMDPNLTKEFVWKKKNNPVQLN--------------CQEKQAELENVQXXXXXXXXXXXXXXXXXXXXXXAKEAQNFR--GRKSDSNFDIEQAKNRSKIRIAEGRAKPIDLLIQYVNEEENTINDNAD--AIIH--EPTQFLVGLSKXXXXXXXXXIHEYSRNMEPGKNTQYWEDIRLITEDELKRVIKTEDD-------------GRTEGVTKECVDDMKQMILQG-TIDESTELLNDAKKMLETGDRRHIDVAYYEYFCSLARVLIAKKRLQERHSNNLRIKLNRLKHEQGLPIEPLFPSA-----------IKPEAQVDTKPTSSK-------KPEQK--------------------------LEREEYDHSRYSPVLLSGEELGDEAIENVIYLADDDEKKLEFMRKKFIKFGSHKINQEDELIKLVQEGDEKG-DLDFSEQIAIEEQSFLWSDKYRPRKPRFLNRVNTGFDWNKYNQTHYDMDNPPPKIVQGYKFNILYPDLIDKTKTPTFELTPCIDDDQ--YAMITFKAGPPYEDIAFKIVNREWETSERHGYKCQFYRDMLQLYFHFKRYRYRK 1745
            GYT+++NPF D  L++ FVWK+K     L                +E + ELE+V+RR  E ER REER  E E+MQR KEA+ +R  G++ D+ F +EQAK RS+IRIA+GRAKPIDLL +Y+ ++E     +A+   +I   EPTQFLVGLS  DL+DLLVDI      +E G+N +YW DI  + EDEL ++ + E+D             GR+     + V       L+G T ++   L    +  L+ G+   +DV Y+E      R  +A+ RL++ H  NLR KL  L+  QG+  EPLFPS            ++ +AQ+   P   K       +PE                            +E E YD + YSP  +   E+   A++ VIY  +DD  K+++ RK+ ++ G+ + ++E+EL++  +EG E G D  FS QI +E+QSFLWSDKYRPRKPRF NRV+TGF WNKYNQTHYD+DNPPPK+VQGYKFN+ YPDLIDK+KTPT+ LTPC D  Q  +A++ F AGPPYEDIAFKIVNREWE S +HG++CQF  ++ QL+FHFKR+RYR+
Sbjct:  354 GYTNEDNPFGDHRLSESFVWKQKLEAEGLTHLSKEEIQELQKKKMEENKLELESVRRRRAEREREREEREKEMEMMQRDKEAEYYRSWGQQEDT-FHLEQAKLRSRIRIADGRAKPIDLLAKYIADQEEDAMASAEFTGVIELLEPTQFLVGLSVEDLEDLLVDIKVVYMQLEKGRNAEYWRDITTVAEDELNKLRRAENDSAGLSAAYGADSRGRSSASISQSVMQSVAETLKGKTYNQLAALERQIEPKLKGGE--GVDVTYWETLAQFVRAQMARTRLRDMHQENLRRKLECLRQSQGIVQEPLFPSGTDQPKPSTSQVVRSDAQLMPPPAVDKLRGEEPDEPEDTQPQIEDPHSAEAIRAARQAQLEAAAMVEEEMYDAACYSPPRVDPTEV---ALDAVIYNPEDDRAKIDYQRKEVLRTGAMRASEEEELMRRAREGMEDGEDAQFSVQIPLEDQSFLWSDKYRPRKPRFFNRVHTGFVWNKYNQTHYDLDNPPPKVVQGYKFNVFYPDLIDKSKTPTYTLTPCEDPSQRDFAILRFSAGPPYEDIAFKIVNREWEYSYKHGFRCQFQNNIFQLWFHFKRFRYRR 938

[Close]

BLAST of Cactin, spliceosome C complex subunit vs. TrEMBL
Match: G7Y8W8 (Uncharacterized protein OS=Clonorchis sinensis OX=79923 GN=CLF_103019 PE=4 SV=1)

HSP 1 Score: 410.223 bits (1053), Expect = 1.683e-128
Identity = 261/592 (44.09%), Postives = 356/592 (60.14%), Query Frame = 3

Query:  213 CGYTDDNNPFMDPNLTKEFVWKKKNNPVQLN--------------CQEKQAELENVQXXXXXXXXXXXXXXXXXXXXXXAKEAQNFR--GRKSDSNFDIEQAKNRSKIRIAEGRAKPIDLLIQYVNEEENTINDNAD--AIIH--EPTQFLVGLSKXXXXXXXXXIHEYSRNMEPGKNTQYWEDIRLITEDELKRVIKTEDD-------------GRTEGVTKECVDDMKQMILQG-TIDESTELLNDAKKMLETGDRRHIDVAYYEYFCSLARVLIAKKRLQERHSNNLRIKLNRLKHEQGLPIEPLFPSA-----------IKPEAQVDTKPTSSK-------KPEQK--------------------------LEREEYDHSRYSPVLLSGEELGDEAIENVIYLADDDEKKLEFMRKKFIKFGSHKINQEDELIKLVQEGDEKG-DLDFSEQIAIEEQSFLWSDKYRPRKPRFLNRVNTGFDWNKYNQTHYDMDNPPPKIVQGYKFNILYPDLIDKTKTPTFELTPCIDDDQ--YAMITFKAGPPYEDIAFKIVNREWETSERHGYKCQFYRDMLQLYFHFKRYRYRK 1745
             GYT+++NPF D  L++ FVWK+K     L                +E + ELE+V+RR  E ER REER  E E+MQR KEA+ +R  G++ D+ F +EQAK RS+IRIA+GRAKPIDLL +Y+ ++E     +A+   +I   EPTQFLVGLS  DL+DLLVDI      +E G+N +YW DI  + EDEL ++ + E+D             GR+     + V       L+G T ++   L    +  L+ G+   +DV Y+E      R  +A+ RL++ H  NLR KL  L+  QG+  EPLFPS            I+ + Q+   P   K       +PE                            +E E YD + YSP  +   E+   A++ VIY  +DD  K+++ RK+ ++ G+ + ++E+EL++  +EG E G D  FS QI +E+QSFLWSDKYRPRKPRF NRV+TGF WNKYNQTHYD+DNPPPK+VQGYKFN+ YPDLIDK+KTPT+ LTPC D  Q  +A++ F AGPPYEDIAFKIVNREWE S +HG++CQF  ++ QL+FHFKR+RYR+
Sbjct:  272 LGYTNEDNPFGDHRLSESFVWKQKLEAEGLTHLSKEEIQELQKKKMEENKLELESVRRRRAEREREREEREKEMEMMQRDKEAEYYRSWGQQEDT-FHLEQAKLRSRIRIADGRAKPIDLLAKYIADQEEDAMASAEFTGVIELLEPTQFLVGLSVEDLEDLLVDIKVVYMQLEKGRNAEYWRDITTVAEDELNKLRRAENDSAGLAAAYGADSRGRSSASISQSVMQSVAETLKGKTYNQLAALERQIEPKLKGGE--GVDVTYWETLAQFVRAQMARTRLRDMHQENLRRKLECLRQSQGIVQEPLFPSGTDQPQPSTSQMIRSDTQLMPPPAVDKLRGEEPDEPEDTQPQIEDPHSAEAIRAARQAQLEAAAMVEEEMYDAACYSPPRVDPTEV---ALDAVIYNPEDDRAKIDYQRKEVLRTGAMRASEEEELMRRAREGMEDGEDAQFSVQIPLEDQSFLWSDKYRPRKPRFFNRVHTGFVWNKYNQTHYDLDNPPPKVVQGYKFNVFYPDLIDKSKTPTYTLTPCEDPSQRDFAILRFSAGPPYEDIAFKIVNREWEYSYKHGFRCQFQNNIFQLWFHFKRFRYRR 857

[Close]

BLAST of Cactin, spliceosome C complex subunit vs. TrEMBL
Match: A0A0R3VYN0 (Uncharacterized protein OS=Taenia asiatica OX=60517 GN=TASK_LOCUS2525 PE=4 SV=1)

HSP 1 Score: 398.282 bits (1022), Expect = 1.515e-126
Identity = 257/591 (43.49%), Postives = 353/591 (59.73%), Query Frame = 3

Query:  213 CGYTDDNNPFMDPNLTKEFVWKKKNNPVQLN--------------CQEKQAELENVQXXXXXXXXXXXXXXXXXXXXXXAKEAQNFR--GRKSDSNFDIEQAKNRSKIRIAEGRAKPIDLLIQYV-NEEENTIN-----DNADAI-IHEPTQFLVGLSKXXXXXXXXXIHEYSRNMEPGKNTQYWEDIRLITEDELKRVIKTED----DGRTEGV--TKECVDDMKQMILQGTIDESTELLNDAKKMLETGDRRHIDVAYYEYFCSLARVLIAKKRLQERHSNNLRIKLNRLKHEQGLPI-----EPLFPSAI----------------------------------------KPEAQVDTKPT---SSKKPEQKL---EREEYDHSRYSPVLLSGEELGDEAIENVIYLADDDEKKLEFMRKKFIKFGSHKINQEDELIKLVQEGDEKGDLDFSEQIAIEEQSFLWSDKYRPRKPRFLNRVNTGFDWNKYNQTHYDMDNPPPKIVQGYKFNILYPDLIDKTKTPTFELTPCIDDDQYAMITFKAGPPYEDIAFKIVNREWETSERHGYKCQFYRDMLQLYFHFKRYRYRK 1745
             GYT+++NPF D +L++ FVW+KK +   L+               +E + ELENV+RR  E ER +EE+  E E++QR +EA+ ++  G++ D+ F +EQAK RS+IRIA+GRAKPIDLL +Y+ +++E + N     D + AI + EPTQFLVGLS  DL+DLLVDI      +E G+N +YW D+ +I EDEL+R+ + ED     GR   V  +   +  +   +   T  +   L    +  L  G+   +DV Y+E         +A+ RL+ERH  +LR KL  L+  QG+        P+FPS                                           P +Q + +PT   SS +PE      + + YD S YSPVLL   +  D  I+ V+Y A DD  KLE+ RK  +  G+ +   E+EL+K  +EG E+GD +FS    +E+QSFLWSDKYRPRKPRF NRV+TGF WNKYNQTHYD+DNPPPK+VQGYKFNI YPDLID TKTPT+  TPC  +  + ++ F AGPPYEDIAFKIV+REWE S +HG++CQF+  + QL+FHFKR+RYR+
Sbjct:   43 LGYTNEDNPFGDRHLSETFVWRKKIDDKGLSHLDSARLQTLQAQKMEENRRELENVRRRRLEREREKEEKEKELEMLQREREAEYYKSWGQQEDT-FHLEQAKLRSRIRIADGRAKPIDLLSKYIADQDEGSQNMTSGGDISSAIEVMEPTQFLVGLSIDDLEDLLVDIKIVYMELEKGQNVEYWRDMTVIVEDELRRLKQDEDAEGGGGRHTSVNISNSVLKSVANTLKSKTYAQLAALERQIQPKLHGGE--GVDVGYWETLSQFVAAQMARTRLRERHQEHLRRKLAFLQQNQGISSTSTDSNPIFPSGSGSTCNMVERIRELQQQVAFKMQRDEVQQSEETRKVSEESPAPASQEEVEPTPGPSSAQPEVPTVLNQPDPYDSSLYSPVLL---DQSDVEIDAVLYDAQDDRAKLEYQRKDVMHTGALRKTAEEELMKRAREGVEEGDAEFSVLAPLEDQSFLWSDKYRPRKPRFFNRVHTGFVWNKYNQTHYDLDNPPPKVVQGYKFNIFYPDLIDMTKTPTYTRTPCDGEPDFEILRFIAGPPYEDIAFKIVSREWEYSYKHGFRCQFHNTIFQLWFHFKRFRYRR 627

[Close]

BLAST of Cactin, spliceosome C complex subunit vs. Ensembl Cavefish
Match: cactin (cactin [Source:NCBI gene;Acc:100126813])

HSP 1 Score: 374.4 bits (960), Expect = 7.664e-120
Identity = 235/563 (41.74%), Postives = 324/563 (57.55%), Query Frame = 3

Query:  213 CGYTDDNNPFMDPNLTKEFVWKK-----------------KNNPVQLNCQEKQAELENVQXXXXXXXXXXXXXXXXXXXXXXAKEAQNFRG-RKSDSNFDIEQAKNRSKIRIAEGRAKPIDLLIQYVNEEENTINDNADAIIHEPTQFLVGLSKXXXXXXXXXIHEYSRNMEPGKNTQYWEDIRLITEDELKRVIKTEDDG-----RTEGVTKECVDDMKQMILQGTIDESTELLNDAKKMLETGDRRHIDVAYYEYFCSLARVLIAKKRLQERHSNNLRIKLNRLKHEQGLPIEPLFPSAIKPEAQVDTKPTSSKK--------------------------PEQKL---EREEYDHSRYSPVLLSGEELGDEAIENVIYLADDDEKKLEFMRKKFIKFGSHKINQEDELIKLVQEGDEKGDLDFSEQIAIEEQSFLWSDKYRPRKPRFLNRVNTGFDWNKYNQTHYDMDNPPPKIVQGYKFNILYPDLIDKTKTPTFELTPCIDDDQYAMITFKAGPPYEDIAFKIVNREWETSERHGYKCQFYRDMLQLYFHFKRYRYRK 1745
             GYT+ +NPF D NL   F W+K                 +N  +Q   +E + EL+ V++   E ER +  R  E E++QR KEA++F+   + + NF + QAK RSKIRI +GRAKPIDLL +Y++ E    +D+    +HEP  FL GL+  D+DDLLVDI  Y + +E GKN  +W D+  ITEDE+ ++ K E  G     R EG+      D++ +    T  +   L  + +  ++ G   ++D+ Y+E      RV +A+ RL+ERH + LR KL +LK EQG+  EPLFP  IK E   +  P S +                            E+ L    + EYD  RYSP LL   EL    ++      ++D ++L   R++    G    + ED  ++  +EG    +  FS ++ +  + +LW+DKYRPRKPRF NRV+TGF+WNKYNQTHYD DNPPPKIVQGYKFNI YPDLIDK  TP + L P  D+  + ++ F AGPPYEDIAFKIVNREWE S RHG++CQF   + QL+FHFKRYRYR+
Sbjct:  159 MGYTNADNPFGDNNLLGTFKWQKALEKKGIGHLGEKELKERNKRIQ---EENRRELQKVKQLRLEREREKAMREQELEMLQREKEAEHFKTWAEQEDNFHLHQAKLRSKIRIRDGRAKPIDLLAKYISAE----DDDLAVEMHEPYTFLNGLTVTDMDDLLVDIKVYMQ-LEQGKNVDFWRDMTTITEDEISKLRKLEASGKGPGDRREGINTSVSTDVQSVFKGKTYSQLQALHMNIESKIQAGGS-NLDIGYWESLLQQVRVYMARARLRERHQDVLRQKLYKLKQEQGVESEPLFP-IIKEEP--EEHPASCRDGEEREENKEEEGEEDGEKSGGVEVVLTEEDLIQQSQAEYDSGRYSPTLLQSSEL---PLDTHTIDVEEDLQRLHLARRQLQVTGDASESAEDAFVRRAKEGMGGDEAQFSVELPLTGKMYLWADKYRPRKPRFFNRVHTGFEWNKYNQTHYDFDNPPPKIVQGYKFNIFYPDLIDKRSTPQYFLEPSPDNKDFGILRFHAGPPYEDIAFKIVNREWEYSHRHGFRCQFANGIFQLWFHFKRYRYRR 706

[Close]

BLAST of Cactin, spliceosome C complex subunit vs. Ensembl Sea Lamprey
Match: ENSPMAT00000010480.1 (pep scaffold:Pmarinus_7.0:GL484446:794:2147:1 gene:ENSPMAG00000009491.1 transcript:ENSPMAT00000010480.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 249.21 bits (635), Expect = 4.448e-78
Identity = 117/210 (55.71%), Postives = 149/210 (70.95%), Query Frame = 3

Query: 1116 EEYDHSRYSPVLLSGEELGDEAIENVIYLADDDEKKLEFMRKKFIKFGSHKINQEDELIKLVQEGDEKGDLDFSEQIAIEEQSFLWSDKYRPRKPRFLNRVNTGFDWNKYNQTHYDMDNPPPKIVQGYKFNILYPDLIDKTKTPTFELTPCIDDDQYAMITFKAGPPYEDIAFKIVNREWETSERHGYKCQFYRDMLQLYFHFKRYRYRK 1745
            EEY+  RYSP LL  +EL    +E  +  A++D ++L   RK+  + GS +   ED   +  +EG    +  FS ++ + ++ +LWSDKYRPRKPRF NRV+TGF+WNKYNQTHYD DNPPPKIVQGYKFNI YPDLIDK  TP + L     D ++A + F AGPPYEDIAFKIV+REWE S RHG++CQF   + QL+FHFKRYRYR+
Sbjct:   63 EEYEAGRYSPTLLPPDEL---PVEAHVMEAEEDNQRLYLARKQLQETGSAEDTAEDAFERRAREGMGTDEARFSVEVPLTDKLYLWSDKYRPRKPRFFNRVHTGFEWNKYNQTHYDFDNPPPKIVQGYKFNIFYPDLIDKKSTPQYFLESSDGDREFATLRFHAGPPYEDIAFKIVSREWEYSHRHGFRCQFANSIFQLWFHFKRYRYRR 269

[Close]

BLAST of Cactin, spliceosome C complex subunit vs. Ensembl Sea Lamprey
Match: CACTIN (cactin, spliceosome C complex subunit [Source:HGNC Symbol;Acc:HGNC:29938])

HSP 1 Score: 70.0922 bits (170), Expect = 4.312e-13
Identity = 66/180 (36.67%), Postives = 98/180 (54.44%), Query Frame = 3

Query:  129 ISKKEEIKNENYDATGFKRSSKVPKQAICGYTDDNNPFMDPNLTKEFVW---------------KKKNNPVQLNCQEKQAELENVQXXXXXXXXXXXXXXXXXXXXXXAKEAQNFRG-RKSDSNFDIEQAKNRSKIRIAEGRAKPIDLLIQYVNEEENTINDNADAI-IHEPTQFLVGLS 617
            +SKKE  + +  +  G+        +   GYT+ +NPF D NL    +                K++N  +Q   +E + EL+ V++   E ER +  R  E E+MQR KEA++F+   + + NF ++QAK RSKIRI +GRAKPIDLL +YV  EE  +     A+ +HEP  FL GL+
Sbjct:  194 LSKKEAKERKRREKMGWG-------EEYMGYTNADNPFGDNNLLGTLIQALETKGISHLSDKDKKERNKGIQ---KENRIELQKVKQLRLEREREQALRDQELEMMQRDKEAEHFKQWEQQEDNFHLQQAKLRSKIRIKDGRAKPIDLLAKYVGMEEEDL-----AVEMHEPYTFLNGLT 358

[Close]

BLAST of Cactin, spliceosome C complex subunit vs. Ensembl Nematostella
Match: EDO39568 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S9T3])

HSP 1 Score: 172.94 bits (437), Expect = 1.932e-51
Identity = 75/106 (70.75%), Postives = 88/106 (83.02%), Query Frame = 3

Query: 1428 FDWNKYNQTHYDMDNPPPKIVQGYKFNILYPDLIDKTKTPTFELTPCIDDDQYAMITFKAGPPYEDIAFKIVNREWETSERHGYKCQFYRDMLQLYFHFKRYRYRK 1745
            ++WNKYNQTHYD DNPPPKIVQGYKFNI YPDLIDKT  P + L PC D   +A++ F AGPPYEDIAFK+VNREWE S RHG++CQF  ++ QL+FHFKRYRYR+
Sbjct:    2 YEWNKYNQTHYDSDNPPPKIVQGYKFNIFYPDLIDKTVAPEYYLEPCSDTKDFAILRFHAGPPYEDIAFKVVNREWEYSHRHGFRCQFQNNIFQLWFHFKRYRYRR 107

[Close]

BLAST of Cactin, spliceosome C complex subunit vs. Ensembl Nematostella
Match: EDO39569 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S9T4])

HSP 1 Score: 101.293 bits (251), Expect = 3.309e-24
Identity = 82/194 (42.27%), Postives = 116/194 (59.79%), Query Frame = 3

Query:  210 ICGYTDDNNPFMDPNLTKEFVW---KKKNNPVQLNCQEKQA-----------ELENVQXXXXXXXXXXXXXXXXXXXXXXAKEAQNF-RGRKSDSNFDIEQAKNRSKIRIAEGRAKPIDLLIQYVNEEENTINDNADAIIHEPTQFLVGLSKXXXXXXXXXIHEYSRNMEPGKNTQYWEDIRLITEDELKRVIK 746
            + GYT+ +NPF D +L   FVW   K+K+    L+  EK+            +LE V++R  E E     R  E+E +QR KEA+ F    K + NF + QA  RS+IRI +GRAK IDLL QY++ +    +DN D  +HEP   LVGL++ DL+DLL DI  Y   M+ GKN +YW+DI +I +DE+K++ K
Sbjct:   45 LLGYTNTDNPFGDAHLLDSFVWHKVKEKHGENHLSEAEKRLRDKTRQEETRRQLEQVRQRRTEREHEMLLREEEKERLQREKEAEYFSEWEKQEDNFHLNQAMLRSQIRIKDGRAKAIDLLAQYISPD----DDNLDIKMHEPYTMLVGLTQSDLEDLLEDIKVYL-EMDQGKNAEYWQDITIICKDEIKKLRK 233

[Close]

BLAST of Cactin, spliceosome C complex subunit vs. Ensembl Medaka
Match: cactin (cactin, spliceosome C complex subunit [Source:NCBI gene;Acc:101170546])

HSP 1 Score: 363.999 bits (933), Expect = 2.064e-114
Identity = 236/599 (39.40%), Postives = 329/599 (54.92%), Query Frame = 3

Query:  213 CGYTDDNNPFMDPNLTKEFVWKK-----------------KNNPVQLNCQEKQAELENVQXXXXXXXXXXXXXXXXXXXXXXAKEAQNFRG-RKSDSNFDIEQAKNRSKIRIAEGRAKPIDLLIQYVNEEENTINDNADAIIHEPTQFLVGLSKXXXXXXXXXIHEYSRNMEPGKNTQYWEDIRLITEDELKRVIKTEDDG-----RTEGVTKECVDDMKQMILQGTIDESTELLNDAKKMLETGDRRHIDVAYYEYFCSLARVLIAKKRLQERHSNNLRIKLNRLKHEQGL---PIEPLF-------------------------PSA------IKPEAQVDTKPTSSK----------------KPEQKLE---------------REEYDHSRYSPVLLSGEELGDEAIENVIYLADDDEKKLEFMRKKFIKFGSHKINQEDELIKLVQEGDEKGDLDFSEQIAIEEQSFLWSDKYRPRKPRFLNRVNTGFDWNKYNQTHYDMDNPPPKIVQGYKFNILYPDLIDKTKTPTFELTPCIDDDQYAMITFKAGPPYEDIAFKIVNREWETSERHGYKCQFYRDMLQLYFHFKRYRYRK 1745
             GYT+ +NPF D NL   F W+K                 +N  +Q   +E + EL+ V++   E ER +  R +E E++QR KEA++F+   + + NF ++QAK RSKIRI +GRAKPIDLL +Y++ E    +D+    +HEP  FL GL+  D+DDLL DI  Y   +E GKN  +W D+  ITEDE+ ++ K E  G     R EG+      D++ +    T  +   L  + +  +  G R ++D+ Y+E      +V +A+ RL+ERH + LR KL +LK EQG+   P+ P+                          PSA         EA+ + +P  S                 K E+K E               + EYD  RYSP LL+  EL    ++      ++D  +L+  R+     G    + ED  ++  +EG    +  FS ++ +  + +LW+DKYRPRKPRF NRV+TGF+WNKYNQTHYD DNPPPKIVQGYKFNI YPDLIDK  TP + L PC D+  + ++ F AGPPYEDIAFKIVNREWE S RHG++CQF   + QL+FHFKRYRYR+
Sbjct:  261 MGYTNADNPFGDNNLLGTFKWQKALVKKGIGHLGEKELKERNKLIQ---EENRRELQKVKQLRLEREREKAMREMELEMLQREKEAEHFKTWAEQEDNFHLQQAKLRSKIRIRDGRAKPIDLLAKYISAE----DDDLAVEMHEPYTFLNGLTVTDMDDLLEDIKVYM-ELEQGKNVDFWRDMTTITEDEISKLRKLEASGKGPGDRREGINTAVSTDVQTVFKGKTYSQLQALHLNIESKIRAG-RSNLDIGYWESLLQQVKVYMARARLRERHQDVLRQKLFKLKQEQGVESEPLFPIIKEEPRDERDGDSRGQSRGATTEDSGPSASSFGRVANREAEDEERPGPSTSAAGGQDEDKGEKGEGKDEEKGEAVEAVLTEEDLIQQSQAEYDSGRYSPTLLTQSEL---PLDTHTITPEEDASRLQLARRLLQVTGDANESAEDAFVRRAREGMGTDEAQFSVEVPVTGKMYLWADKYRPRKPRFFNRVHTGFEWNKYNQTHYDFDNPPPKIVQGYKFNIFYPDLIDKRSTPQYFLEPCPDNKDFGILRFHAGPPYEDIAFKIVNREWEYSHRHGFRCQFANGIFQLWFHFKRYRYRR 847

[Close]

BLAST of Cactin, spliceosome C complex subunit vs. Planmine SMEST
Match: SMESG000061791.1 (SMESG000061791.1)

HSP 1 Score: 1053.89 bits (2724), Expect = 0.000e+0
Identity = 571/572 (99.83%), Postives = 572/572 (100.00%), Query Frame = 3

Query:   30 MNLEKNIXXXXXXXXXXXXXXXXXXXXXXXPEFISKKEEIKNENYDATGFKRSSKVPKQAICGYTDDNNPFMDPNLTKEFVWKKKNNPVQLNCQEKQAELENVQXXXXXXXXXXXXXXXXXXXXXXAKEAQNFRGRKSDSNFDIEQAKNRSKIRIAEGRAKPIDLLIQYVNEEENTINDNADAIIHEPTQFLVGLSKXXXXXXXXXIHEYSRNMEPGKNTQYWEDIRLITEDELKRVIKTEDDGRTEGVTKECVDDMKQMILQGTIDESTELLNDAKKMLETGDRRHIDVAYYEYFCSLARVLIAKKRLQERHSNNLRIKLNRLKHEQGLPIEPLFPSAIKPEAQVDTKPTSSKKPEQKLEREEYDHSRYSPVLLSGEELGDEAIENVIYLADDDEKKLEFMRKKFIKFGSHKINQEDELIKLVQEGDEKGDLDFSEQIAIEEQSFLWSDKYRPRKPRFLNRVNTGFDWNKYNQTHYDMDNPPPKIVQGYKFNILYPDLIDKTKTPTFELTPCIDDDQYAMITFKAGPPYEDIAFKIVNREWETSERHGYKCQFYRDMLQLYFHFKRYRYRK 1745
            MNLEKNISSEGSHKKSKKKHKKHLRRDSSSPEFISKKEEIKNENYDATGFKRSSKVPKQAICGYTDDNNPFMDPNLTKEFVWKKKNNPVQLNCQEKQAELENVQRRMKEHERLREERLLEQEIMQRAKEAQNFRGRKSDSNFDIEQAKNRSKIRIAEGRAKPIDLLIQYVNEEENTINDNADAIIHEPTQFLVGLSKLDLDDLLVDIHEYSRNMEPGKNTQYWEDIRLITEDELKRVIKTEDDGRTEGVTKECVDDMKQMILQGTI+ESTELLNDAKKMLETGDRRHIDVAYYEYFCSLARVLIAKKRLQERHSNNLRIKLNRLKHEQGLPIEPLFPSAIKPEAQVDTKPTSSKKPEQKLEREEYDHSRYSPVLLSGEELGDEAIENVIYLADDDEKKLEFMRKKFIKFGSHKINQEDELIKLVQEGDEKGDLDFSEQIAIEEQSFLWSDKYRPRKPRFLNRVNTGFDWNKYNQTHYDMDNPPPKIVQGYKFNILYPDLIDKTKTPTFELTPCIDDDQYAMITFKAGPPYEDIAFKIVNREWETSERHGYKCQFYRDMLQLYFHFKRYRYRK
Sbjct:    1 MNLEKNISSEGSHKKSKKKHKKHLRRDSSSPEFISKKEEIKNENYDATGFKRSSKVPKQAICGYTDDNNPFMDPNLTKEFVWKKKNNPVQLNCQEKQAELENVQRRMKEHERLREERLLEQEIMQRAKEAQNFRGRKSDSNFDIEQAKNRSKIRIAEGRAKPIDLLIQYVNEEENTINDNADAIIHEPTQFLVGLSKLDLDDLLVDIHEYSRNMEPGKNTQYWEDIRLITEDELKRVIKTEDDGRTEGVTKECVDDMKQMILQGTIEESTELLNDAKKMLETGDRRHIDVAYYEYFCSLARVLIAKKRLQERHSNNLRIKLNRLKHEQGLPIEPLFPSAIKPEAQVDTKPTSSKKPEQKLEREEYDHSRYSPVLLSGEELGDEAIENVIYLADDDEKKLEFMRKKFIKFGSHKINQEDELIKLVQEGDEKGDLDFSEQIAIEEQSFLWSDKYRPRKPRFLNRVNTGFDWNKYNQTHYDMDNPPPKIVQGYKFNILYPDLIDKTKTPTFELTPCIDDDQYAMITFKAGPPYEDIAFKIVNREWETSERHGYKCQFYRDMLQLYFHFKRYRYRK 572

[Close]

BLAST of Cactin, spliceosome C complex subunit vs. Planmine SMEST
Match: SMESG000026741.1 (SMESG000026741.1)

HSP 1 Score: 642.884 bits (1657), Expect = 0.000e+0
Identity = 343/544 (63.05%), Postives = 428/544 (78.68%), Query Frame = 3

Query:  120 PEFISKKEEIKNENYDATGFKRSSKVPKQAICGYTDDNNPFMDPNLTKEFVWKKKNNPVQLNCQEKQAELENVQXXXXXXXXXXXXXXXXXXXXXXAKEAQNFRGRKSDSNFDIEQAKNRSKIRIAEGRAKPIDLLIQYVNEEENTINDNADAIIHEPTQFLVGLSKXXXXXXXXXIHEYSRNMEPGKNTQYWEDIRLITEDELKRVIKTEDDGRTEGVTKECVDDMKQMILQGTIDESTELLNDAKKMLETGDRRHIDVAYYEYFCSLARVLIAKKRLQERHSNNLRIKLNRLKHEQGLPIE--PLFPSAIKPEAQVDTKPTSSKKPEQKLEREEYDHSRYSPVLLSGEELGDEAIENVIYLADDDEKKLEFMRKKFIKFGSHKINQEDELIKLVQEGDEKGDLDFSEQIAIEEQSFLWSDKYRPRKPRFLNRVNTGFDWNKYNQTHYDMDNPPPKIVQGYKFNILYPDLIDKTKTPTFELTPCIDDDQYAMITFKAGPPYEDIAFKIVNREWETSERHGYKCQFYRDMLQLYFHFKRYRYRK 1745
            PE +   E    E YDATG+KRS+ + K+ ICG+TDD NPFMDPNLT++F+WKK    ++++CQ K+AELE VQ+RM+EHERLREER +EQEI+QRAKE+QN+ GRK+DS FD++QA  RSKIRI   R +PID LIQY+NEE N  + + + I++EPTQ+L+ L K  L +LLVDI  YS NM PGKNTQYW D ++I EDEL ++ +TE+ GR E ++KE ++ MK M+L GTIDE+ EL ND+K+MLETGDRRHID++YYEYFC+ A++LIAK+RLQE H  NL+I+L +LK EQGL     P     IK E    TKP        K EREEY +  Y PVL+S  ELG+E I+ VIY A+DDE+KL  MRK+F+ FG     +ED+L+ L Q+GDEK D++F++Q+ +E+ SFLWSDKYRPRKPRFLNRVNTGFDWNKYNQTHYD+DNPPPKIVQGYKFNILYPDLIDK+KTPTFEL+ C D+DQ A+I FKAGPPY+DIAFKIVN+EWETSER GYKCQFY +MLQ++FHFKRYRYRK
Sbjct:   41 PELVYHIENEYKEKYDATGYKRSN-IRKKDICGFTDDVNPFMDPNLTEQFIWKKNKRQIKMDCQTKEAELEKVQKRMREHERLREERQIEQEIIQRAKESQNYLGRKNDSTFDLDQAIVRSKIRINSDRGQPIDYLIQYINEE-NECSTDTNVIMNEPTQYLLMLDKQQLGNLLVDIDNYSCNMVPGKNTQYWADFKIIVEDELFKLNRTEN-GRDEALSKESIEAMKDMVLSGTIDEAIELYNDSKQMLETGDRRHIDISYYEYFCNFAKILIAKRRLQENHMRNLQIQLKKLKEEQGLDSSSLPTLKDNIKEEVN-KTKP--------KDEREEYIYKLYEPVLISEHELGEEVIDYVIYRAEDDERKLISMRKQFLTFGHLSSTKEDQLLLLAQKGDEKDDVNFNDQVIVEDNSFLWSDKYRPRKPRFLNRVNTGFDWNKYNQTHYDIDNPPPKIVQGYKFNILYPDLIDKSKTPTFELSVCPDNDQEAIINFKAGPPYQDIAFKIVNKEWETSERFGYKCQFYCNMLQVHFHFKRYRYRK 572

The following BLAST results are available for this feature:

BLAST of Cactin, spliceosome C complex subunit vs. Ensembl Human
BLAST of Cactin, spliceosome C complex subunit vs. Ensembl Celegans
BLAST of Cactin, spliceosome C complex subunit vs. Ensembl Fly
BLAST of Cactin, spliceosome C complex subunit vs. Ensembl Zebrafish
BLAST of Cactin, spliceosome C complex subunit vs. Ensembl Xenopus
BLAST of Cactin, spliceosome C complex subunit vs. Ensembl Mouse
BLAST of Cactin, spliceosome C complex subunit vs. UniProt/SwissProt
BLAST of Cactin, spliceosome C complex subunit vs. TrEMBL
BLAST of Cactin, spliceosome C complex subunit vs. Ensembl Cavefish
BLAST of Cactin, spliceosome C complex subunit vs. Ensembl Sea Lamprey
BLAST of Cactin, spliceosome C complex subunit vs. Ensembl Yeast
BLAST of Cactin, spliceosome C complex subunit vs. Ensembl Nematostella
BLAST of Cactin, spliceosome C complex subunit vs. Ensembl Medaka
BLAST of Cactin, spliceosome C complex subunit vs. Planmine SMEST

BLAST of Cactin, spliceosome C complex subunit vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5


Match Name	E-value	Identity	Description
CACTIN	1.281e-119	39.93	cactin, spliceosome C complex subunit [Source:HGNC...	[more]
CACTIN	1.281e-119	39.93	cactin, spliceosome C complex subunit [Source:HGNC...	[more]
CACTIN	1.281e-119	39.93	cactin, spliceosome C complex subunit [Source:HGNC...	[more]
CACTIN	1.281e-119	39.93	cactin, spliceosome C complex subunit [Source:HGNC...	[more]
CACTIN	2.766e-77	54.29	cactin, spliceosome C complex subunit [Source:HGNC...	[more]

BLAST of Cactin, spliceosome C complex subunit vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 4


Match Name	E-value	Identity	Description
cacn-1	5.158e-83	35.17	Cactin [Source:UniProtKB/Swiss-Prot;Acc:G5EG14]	[more]
cacn-1	5.158e-83	35.17	Cactin [Source:UniProtKB/Swiss-Prot;Acc:G5EG14]	[more]
cacn-1	3.154e-68	40.17	Cactin [Source:UniProtKB/Swiss-Prot;Acc:G5EG14]	[more]
cacn-1	3.662e-66	64.29	Cactin [Source:UniProtKB/Swiss-Prot;Acc:G5EG14]	[more]

BLAST of Cactin, spliceosome C complex subunit vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 1


Match Name	E-value	Identity	Description
cactin	5.839e-102	38.53	gene:FBgn0031114 transcript:FBtr0340400	[more]

BLAST of Cactin, spliceosome C complex subunit vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 2


Match Name	E-value	Identity	Description
cactin	1.551e-109	38.69	cactin [Source:NCBI gene;Acc:100126813]	[more]
cactin	4.438e-18	35.66	cactin [Source:NCBI gene;Acc:100126813]	[more]

BLAST of Cactin, spliceosome C complex subunit vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 1


Match Name	E-value	Identity	Description
CACTIN	7.592e-122	41.96	cactin, spliceosome C complex subunit [Source:NCBI...	[more]

BLAST of Cactin, spliceosome C complex subunit vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 2


Match Name	E-value	Identity	Description
Cactin	1.403e-115	40.03	cactin, spliceosome C complex subunit [Source:MGI ...	[more]
Cactin	1.939e-28	39.58	cactin, spliceosome C complex subunit [Source:MGI ...	[more]

BLAST of Cactin, spliceosome C complex subunit vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5


Match Name	E-value	Identity	Description
sp\|Q8WUQ7\|CATIN_HUMAN	6.150e-119	39.93	Cactin OS=Homo sapiens OX=9606 GN=CACTIN PE=1 SV=3	[more]
sp\|Q9CS00\|CATIN_MOUSE	9.813e-115	40.03	Cactin OS=Mus musculus OX=10090 GN=Cactin PE=1 SV=...	[more]
sp\|F1Q8W0\|CATIN_DANRE	1.170e-108	38.69	Cactin OS=Danio rerio OX=7955 GN=cactin PE=2 SV=1	[more]
sp\|Q9VR99\|CATIN_DROME	5.853e-101	38.53	Cactin OS=Drosophila melanogaster OX=7227 GN=cacti...	[more]
sp\|G5EG14\|CATIN_CAEEL	6.562e-82	35.17	Cactin OS=Caenorhabditis elegans OX=6239 GN=cacn-1...	[more]

BLAST of Cactin, spliceosome C complex subunit vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5


Match Name	E-value	Identity	Description
A0A4S2LMZ6	8.646e-130	43.75	Uncharacterized protein OS=Opisthorchis felineus O...	[more]
A0A3R7ETC6	8.633e-129	44.09	Cactin OS=Clonorchis sinensis OX=79923 GN=CACTIN P...	[more]
A0A1S8WZG4	1.492e-128	44.16	Uncharacterized protein OS=Opisthorchis viverrini ...	[more]
G7Y8W8	1.683e-128	44.09	Uncharacterized protein OS=Clonorchis sinensis OX=...	[more]
A0A0R3VYN0	1.515e-126	43.49	Uncharacterized protein OS=Taenia asiatica OX=6051...	[more]

BLAST of Cactin, spliceosome C complex subunit vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 1


Match Name	E-value	Identity	Description
cactin	7.664e-120	41.74	cactin [Source:NCBI gene;Acc:100126813]	[more]

BLAST of Cactin, spliceosome C complex subunit vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 2


Match Name	E-value	Identity	Description
ENSPMAT00000010480.1	4.448e-78	55.71	pep scaffold:Pmarinus_7.0:GL484446:794:2147:1 gene...	[more]
CACTIN	4.312e-13	36.67	cactin, spliceosome C complex subunit [Source:HGNC...	[more]

BLAST of Cactin, spliceosome C complex subunit vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0


Match Name	E-value	Identity	Description

BLAST of Cactin, spliceosome C complex subunit vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 2


Match Name	E-value	Identity	Description
EDO39568	1.932e-51	70.75	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO39569	3.309e-24	42.27	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]

BLAST of Cactin, spliceosome C complex subunit vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 1


Match Name	E-value	Identity	Description
cactin	2.064e-114	39.40	cactin, spliceosome C complex subunit [Source:NCBI...	[more]

BLAST of Cactin, spliceosome C complex subunit vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 2


Match Name	E-value	Identity	Description
SMESG000061791.1	0.000e+0	99.83	SMESG000061791.1	[more]
SMESG000026741.1	0.000e+0	63.05	SMESG000026741.1	[more]

Analyses

This transcript is derived from or has results from the following analyses


Analysis Name	Date Performed
Embryonic Stages	2016-07-25
Schmidtea mediterranea smed_20140614 BLASTX Human e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL	2020-05-01
Schmidtea mediterranea Sexual smed_20140614 transcriptome	2016-07-25
Schmidtea mediteranean smed_20140614 Interproscan	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST	2020-05-08

Sequences

The following sequences are available for this feature:

transcript sequence
protein sequence

transcript sequence

>SMED30013169 ID=SMED30013169|Name=Cactin, spliceosome C complex subunit|organism=Schmidtea mediterranea sexual|type=transcript|length=2034bp
AATCTATATAAATCTTATATGCACTAATTATGAATTTAGAGAAAAACATA
AGTTCAGAAGGTAGTCATAAAAAATCTAAAAAAAAACACAAAAAACACCT
TCGAAGAGATTCGTCTTCTCCAGAATTCATAAGTAAAAAGGAAGAAATTA
AAAATGAAAATTACGACGCGACTGGATTTAAACGAAGTTCAAAAGTTCCA
AAACAGGCTATTTGTGGATATACTGATGATAACAATCCATTTATGGATCC
TAATTTAACGAAGGAATTTGTTTGGAAAAAGAAAAATAATCCTGTTCAAT
TAAATTGCCAAGAAAAGCAAGCAGAATTGGAAAATGTTCAACGAAGAATG
AAAGAACATGAAAGGCTGCGCGAGGAACGATTACTCGAACAGGAAATAAT
GCAACGAGCAAAAGAAGCACAGAATTTCCGTGGCCGAAAATCTGATTCCA
ATTTTGATATAGAGCAAGCTAAAAATCGATCTAAAATTAGAATAGCTGAA
GGTCGAGCAAAACCGATAGATTTACTAATTCAATACGTAAATGAAGAAGA
AAATACGATTAATGATAATGCTGATGCGATTATCCACGAACCGACACAAT
TTTTGGTTGGATTATCAAAATTAGATTTGGATGATTTGTTAGTGGATATC
CACGAATACTCACGAAACATGGAACCGGGCAAAAACACCCAATATTGGGA
AGATATCCGTTTAATAACCGAAGATGAGTTGAAAAGAGTCATCAAAACGG
AAGACGATGGTCGAACTGAAGGAGTAACAAAGGAATGCGTTGACGACATG
AAACAAATGATTCTTCAAGGAACTATCGACGAGTCAACGGAATTATTAAA
TGACGCTAAAAAGATGCTGGAAACAGGCGATCGCCGACATATCGATGTTG
CTTATTACGAATATTTTTGCAGTCTCGCCCGAGTTTTAATTGCTAAAAAA
CGGTTACAAGAGCGCCATTCCAACAATTTACGAATAAAATTGAACCGATT
AAAACACGAGCAAGGATTACCGATTGAGCCGCTTTTCCCCAGTGCGATAA
AACCGGAAGCACAAGTTGACACGAAACCGACAAGTTCCAAGAAACCCGAA
CAGAAGTTGGAACGAGAAGAATATGATCATAGTCGATACAGTCCGGTGTT
GTTGTCAGGTGAAGAGTTGGGCGACGAGGCAATTGAAAATGTAATTTATC
TCGCCGACGACGACGAGAAAAAACTAGAATTCATGAGAAAAAAATTCATC
AAGTTCGGCAGTCATAAAATCAATCAGGAAGACGAATTGATAAAATTGGT
GCAGGAAGGTGACGAGAAAGGTGATTTGGATTTCAGTGAGCAGATCGCAA
TTGAGGAGCAATCGTTTCTCTGGTCGGACAAATATCGACCGAGGAAGCCT
CGATTTCTCAACCGGGTCAATACGGGATTCGACTGGAACAAATACAATCA
AACCCATTATGACATGGACAACCCACCACCGAAAATCGTCCAGGGATACA
AATTCAATATTCTCTATCCGGATTTGATCGATAAAACAAAAACTCCCACA
TTCGAGTTGACTCCGTGCATCGATGACGATCAATACGCGATGATCACGTT
CAAGGCCGGGCCGCCATATGAGGACATCGCTTTCAAAATTGTGAACCGTG
AATGGGAGACCAGTGAAAGGCATGGTTACAAGTGCCAGTTCTATCGTGAT
ATGCTGCAGTTATATTTTCACTTCAAGCGATATCGATATAGAAAATAAAT
TTGTTCTTGTTATTTTAAATTTGATTTTAATCCATTTATTTAGATTGCTG
CCAGATTTTGACCAATGAAGACTGAGGCGGGTTCTGAAATCAGCTGGTAC
TACGTCGGATACATCCTCCAAAGCCTTTTTAACTGATAAAATTGATCTGA
AAGTATCATTAATTTAAAATATTCGGTCTGAGATCCATTATTGTAAAATC
CAAAATAATTTATACTAACACTTTGTTTAAGCCATGACCCCTCTGTTGTG
GTCTCGATTTTGGTGAGTCTCAACTTGCACTGGT

protein sequence of SMED30013169-orf-1

>SMED30013169-orf-1 ID=SMED30013169-orf-1|Name=SMED30013169-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=573bp
MNLEKNISSEGSHKKSKKKHKKHLRRDSSSPEFISKKEEIKNENYDATGF
KRSSKVPKQAICGYTDDNNPFMDPNLTKEFVWKKKNNPVQLNCQEKQAEL
ENVQRRMKEHERLREERLLEQEIMQRAKEAQNFRGRKSDSNFDIEQAKNR
SKIRIAEGRAKPIDLLIQYVNEEENTINDNADAIIHEPTQFLVGLSKLDL
DDLLVDIHEYSRNMEPGKNTQYWEDIRLITEDELKRVIKTEDDGRTEGVT
KECVDDMKQMILQGTIDESTELLNDAKKMLETGDRRHIDVAYYEYFCSLA
RVLIAKKRLQERHSNNLRIKLNRLKHEQGLPIEPLFPSAIKPEAQVDTKP
TSSKKPEQKLEREEYDHSRYSPVLLSGEELGDEAIENVIYLADDDEKKLE
FMRKKFIKFGSHKINQEDELIKLVQEGDEKGDLDFSEQIAIEEQSFLWSD
KYRPRKPRFLNRVNTGFDWNKYNQTHYDMDNPPPKIVQGYKFNILYPDLI
DKTKTPTFELTPCIDDDQYAMITFKAGPPYEDIAFKIVNREWETSERHGY
KCQFYRDMLQLYFHFKRYRYRK*

Annotated Terms

The following terms have been associated with this transcript:

Vocabulary: **biological process**
Term	Definition
GO:0043124	negative regulation of I-kappaB kinase/NF-kappaB signaling
GO:0000398	mRNA splicing, via spliceosome
GO:0001933	negative regulation of protein phosphorylation
GO:0002376	immune system process
GO:0006397	mRNA processing
GO:0007275	multicellular organism development
GO:0008380	RNA splicing
GO:0031665	negative regulation of lipopolysaccharide-mediated signaling pathway
GO:0032088	negative regulation of NF-kappaB transcription factor activity
GO:0032688	negative regulation of interferon-beta production
GO:0032717	negative regulation of interleukin-8 production
GO:0032720	negative regulation of tumor necrosis factor production
GO:0034122	negative regulation of toll-like receptor signaling pathway
GO:0045087	innate immune response
GO:0060339	negative regulation of type I interferon-mediated signaling pathway
GO:0071222	cellular response to lipopolysaccharide
GO:0071347	cellular response to interleukin-1
GO:0071356	cellular response to tumor necrosis factor

Vocabulary: **Planarian Anatomy**
Term	Definition
PLANA:0000070	intestinal phagocyte
PLANA:0000429	neoblast
PLANA:0002109	X1 cell
PLANA:0002111	X2 cell

Vocabulary: **INTERPRO**
Term	Definition
IPR019134	Cactin_C
IPR018816	Cactin_central

Vocabulary: **molecular function**
Term	Definition
GO:0005515	protein binding
GO:0003723	RNA binding

Vocabulary: **cellular component**
Term	Definition
GO:0005634	nucleus
GO:0005654	nucleoplasm
GO:0005681	spliceosomal complex
GO:0005829	cytosol
GO:0016607	nuclear speck
GO:0070062	extracellular exosome
GO:0071013	catalytic step 2 spliceosome

InterPro

Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01


IPR Term	IPR Description	Source	Source Term	Source Description	Alignment
None	No IPR available	COILS	Coil	Coil	coord: 96..133
None	No IPR available	SMART	SM01050	CactinC_cactus_3	coord: 451..575 e-value: 1.1E-76 score: 270.8
None	No IPR available	MOBIDB_LITE	mobidb-lite	disorder_prediction	coord: 339..369
None	No IPR available	MOBIDB_LITE	mobidb-lite	disorder_prediction	coord: 351..369
None	No IPR available	MOBIDB_LITE	mobidb-lite	disorder_prediction	coord: 1..40
None	No IPR available	PANTHER	PTHR21737	POLYGLUTAMINE BINDING PROTEIN 1/MARVEL MEMBRANE-ASSOCIATING DOMAIN CONTAINING 3	coord: 38..575
None	No IPR available	PANTHER	PTHR21737:SF4	CACTIN	coord: 38..575
IPR018816	Cactin, central domain	PFAM	PF10312	Cactin_mid	coord: 139..316 e-value: 8.4E-31 score: 107.2
IPR019134	Cactin, C-terminal	PFAM	PF09732	CactinC_cactus	coord: 451..575 e-value: 1.3E-55 score: 186.6

Main menu

Cactin, spliceosome C complex subunit

Zeng et. al., 2018

▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Overview

Single cell RNA-seq of pluripotent neoblasts and its early progenies

Explore this single cell expression dataset with our NB Cluster Shiny App

Neoblast Population

Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Davies et. al., 2017

PAGE et. al., 2020

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE

PAGE Curations: 8

Owlery

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