KHD-1

Overview


Name	KHD-1 (AFD29610.1)
Smed ID	SMED30013157
Length (bp)	1677

Neoblast Clusters

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Overview

Single cell RNA-seq of pluripotent neoblasts and its early progenies

We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)

Explore this single cell expression dataset with our NB Cluster Shiny App

Neoblast Population

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.

Expression of KHD-1 (SMED30013157) t-SNE clustered cells

Violin plots show distribution of expression levels for KHD-1 (SMED30013157) in cells (dots) of each of the 12 neoblast clusters.

Sub-lethal Irradiated Surviving X1 and X2 Cell Population

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of KHD-1 (SMED30013157) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for KHD-1 (SMED30013157) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

Anatomical Expression

PAGE et. al., 2020

SMED30013157

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE

PAGE Curations: 18

Expressed In	Reference Transcript	Gene Models	Published Transcript	Transcriptome	Publication
X1 cell	SMED30013157	SMESG000070471.1	SmedASXL_003885	SmedAsxl_ww_GCZZ01	PMID:26114597 Zhu et al., 2015
pharynx	SMED30013157	SMESG000070471.1	dd_Smed_v4_294_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
protonephridia	SMED30013157	SMESG000070471.1	dd_Smed_v4_294_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
nervous system	SMED30013157	SMESG000070471.1	dd_Smed_v4_294_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
gut	SMED30013157	SMESG000070471.1	dd_Smed_v4_294_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
epidermis	SMED30013157	SMESG000070471.1	dd_Smed_v4_294_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
cephalic ganglia	SMED30013157	SMESG000070471.1	dd_Smed_v4_294_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
neoblast	SMED30013157	SMESG000070471.1	dd_Smed_v4_294_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
parenchyma	SMED30013157	SMESG000070471.1	dd_Smed_v4_294_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
parenchymal cell	SMED30013157	SMESG000070471.1	dd_Smed_v4_294_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
muscle cell	SMED30013157	SMESG000070471.1	dd_Smed_v4_294_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
cilated neuron	SMED30013157	SMESG000070471.1	dd_Smed_v4_294_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
Smed sexual biotype	SMED30013157	SMESG000070471.1	Contig47058	newmark_ests	PMID:29674431 Fincher et al., 2018
Smed sexual biotype	SMED30013157	SMESG000070471.1	Contig47058	uc_Smed_v2	PMID:29674431 Fincher et al., 2018
neoblast	SMED30013157	SMESG000070471.1	dd_Smed_v6_294_0	dd_Smed_v6	PMID:29674432 Plass et al., 2018
Category 1 cell	SMED30013157	SMESG000070471.1	NB.19.5f	smed_ncbi_20200123	PMID:18786419 Eisenhoffer et al., 2008
Category 1 cell	SMED30013157	SMESG000070471.1	NB.19.5f	smed_ncbi_20200123	PMID:18786419 Eisenhoffer et al., 2008
neoblast	SMED30013157	SMESG000070471.1	SMED_01038_V2	GPL14150	PMID:22385657 Wagner et al., 2012

Note: Hover over icons to view figure legend

Homology

[Close]

BLAST of KHD-1 vs. Ensembl Human
Match: KHDRBS3 (KH RNA binding domain containing, signal transduction associated 3 [Source:HGNC Symbol;Acc:HGNC:18117])

HSP 1 Score: 117.857 bits (294), Expect = 2.046e-30
Identity = 56/101 (55.45%), Postives = 74/101 (73.27%), Query Frame = 3

Query:  372 IPVEAYPNVNFVGKLLGPAGKTLKTVQEQTNTKMSILGSGSLRNPEKEQELLNSGDPKYNHLRDRLHLQIDSIGNPSEAYYNISYALAEVKKVMIPDPNEQ 674
            IPV+ +P  NFVGKLLGP G +LK +QE+T TKMSILG GS+R+  KE+EL  SG+ KY HL D LH+ I+    P+EAY  + +AL E+KK +IPD N++
Sbjct:   35 IPVKQFPKFNFVGKLLGPRGNSLKRLQEETLTKMSILGKGSMRDKAKEEELRKSGEAKYFHLNDDLHVLIEVFAPPAEAYARMGHALEEIKKFLIPDYNDE 135

[Close]

BLAST of KHD-1 vs. Ensembl Human
Match: KHDRBS2 (KH RNA binding domain containing, signal transduction associated 2 [Source:HGNC Symbol;Acc:HGNC:18114])

HSP 1 Score: 119.398 bits (298), Expect = 6.018e-29
Identity = 56/101 (55.45%), Postives = 73/101 (72.28%), Query Frame = 3

Query:  372 IPVEAYPNVNFVGKLLGPAGKTLKTVQEQTNTKMSILGSGSLRNPEKEQELLNSGDPKYNHLRDRLHLQIDSIGNPSEAYYNISYALAEVKKVMIPDPNEQ 674
            IPV+ YP  NFVGKLLGP G +LK +QE+T  KMSILG GS+R+  KE+EL  SG+ KY HL D LH+ I+    P EAY  +S+AL E+KK ++PD N++
Sbjct:   66 IPVKQYPKFNFVGKLLGPRGNSLKRLQEETGAKMSILGKGSMRDKAKEEELRKSGEAKYAHLSDELHVLIEVFAPPGEAYSRMSHALEEIKKFLVPDYNDE 166

[Close]

BLAST of KHD-1 vs. Ensembl Human
Match: KHDRBS3 (KH RNA binding domain containing, signal transduction associated 3 [Source:HGNC Symbol;Acc:HGNC:18117])

HSP 1 Score: 117.087 bits (292), Expect = 7.762e-29
Identity = 56/101 (55.45%), Postives = 74/101 (73.27%), Query Frame = 3

Query:  372 IPVEAYPNVNFVGKLLGPAGKTLKTVQEQTNTKMSILGSGSLRNPEKEQELLNSGDPKYNHLRDRLHLQIDSIGNPSEAYYNISYALAEVKKVMIPDPNEQ 674
            IPV+ +P  NFVGKLLGP G +LK +QE+T TKMSILG GS+R+  KE+EL  SG+ KY HL D LH+ I+    P+EAY  + +AL E+KK +IPD N++
Sbjct:   34 IPVKQFPKFNFVGKLLGPRGNSLKRLQEETLTKMSILGKGSMRDKAKEEELRKSGEAKYFHLNDDLHVLIEVFAPPAEAYARMGHALEEIKKFLIPDYNDE 134

[Close]

BLAST of KHD-1 vs. Ensembl Human
Match: KHDRBS3 (KH RNA binding domain containing, signal transduction associated 3 [Source:HGNC Symbol;Acc:HGNC:18117])

HSP 1 Score: 116.701 bits (291), Expect = 4.432e-28
Identity = 56/101 (55.45%), Postives = 74/101 (73.27%), Query Frame = 3

Query:  372 IPVEAYPNVNFVGKLLGPAGKTLKTVQEQTNTKMSILGSGSLRNPEKEQELLNSGDPKYNHLRDRLHLQIDSIGNPSEAYYNISYALAEVKKVMIPDPNEQ 674
            IPV+ +P  NFVGKLLGP G +LK +QE+T TKMSILG GS+R+  KE+EL  SG+ KY HL D LH+ I+    P+EAY  + +AL E+KK +IPD N++
Sbjct:   62 IPVKQFPKFNFVGKLLGPRGNSLKRLQEETLTKMSILGKGSMRDKAKEEELRKSGEAKYFHLNDDLHVLIEVFAPPAEAYARMGHALEEIKKFLIPDYNDE 162

[Close]

BLAST of KHD-1 vs. Ensembl Human
Match: KHDRBS1 (KH RNA binding domain containing, signal transduction associated 1 [Source:HGNC Symbol;Acc:HGNC:18116])

HSP 1 Score: 112.464 bits (280), Expect = 4.883e-26
Identity = 52/97 (53.61%), Postives = 70/97 (72.16%), Query Frame = 3

Query:  372 IPVEAYPNVNFVGKLLGPAGKTLKTVQEQTNTKMSILGSGSLRNPEKEQELLNSGDPKYNHLRDRLHLQIDSIGNPSEAYYNISYALAEVKKVMIPD 662
            IPV+ YP  NFVGK+LGP G T+K +QE+T  K+S+LG GS+R+  KE+EL   GDPKY HL   LH+ I+  G P EAY  +++A+ EVKK ++PD
Sbjct:  162 IPVKQYPKFNFVGKILGPQGNTIKRLQEETGAKISVLGKGSMRDKAKEEELRKGGDPKYAHLNMDLHVFIEVFGPPCEAYALMAHAMEEVKKFLVPD 258

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BLAST of KHD-1 vs. Ensembl Celegans
Match: E02D9.1 (pep chromosome:WBcel235:I:6800386:6803841:1 gene:WBGene00017098.1 transcript:E02D9.1c.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:E02D9.1)

HSP 1 Score: 85.1149 bits (209), Expect = 7.596e-18
Identity = 37/106 (34.91%), Postives = 65/106 (61.32%), Query Frame = 3

Query:  372 IPVEAYPNVNFVGKLLGPAGKTLKTVQEQTNTKMSILGSGSLRNPEKEQELLNSGDPKYNHLRDRLHLQIDSIGNPSEAYYNISYALAEVKKVMIPDPNEQAPGQM 689
            +P+  +PN NF+GK+LGP G TL+T+ +     + ILG GS ++ EKE ELL SGDP++ H    LH++++++     AY  ++  + E+ +++ P   +  P  +
Sbjct:  135 VPIYRHPNFNFIGKVLGPKGATLQTLCKTHKCHIYILGRGSTKDREKEAELLASGDPQHAHFSGPLHVKVETVAPAYIAYGRVAAVIEELSRILQPIHEDTTPAHL 240

[Close]

BLAST of KHD-1 vs. Ensembl Celegans
Match: E02D9.1 (pep chromosome:WBcel235:I:6800386:6801970:1 gene:WBGene00017098.1 transcript:E02D9.1b.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:E02D9.1)

HSP 1 Score: 84.7297 bits (208), Expect = 7.753e-18
Identity = 37/106 (34.91%), Postives = 65/106 (61.32%), Query Frame = 3

Query:  372 IPVEAYPNVNFVGKLLGPAGKTLKTVQEQTNTKMSILGSGSLRNPEKEQELLNSGDPKYNHLRDRLHLQIDSIGNPSEAYYNISYALAEVKKVMIPDPNEQAPGQM 689
            +P+  +PN NF+GK+LGP G TL+T+ +     + ILG GS ++ EKE ELL SGDP++ H    LH++++++     AY  ++  + E+ +++ P   +  P  +
Sbjct:  135 VPIYRHPNFNFIGKVLGPKGATLQTLCKTHKCHIYILGRGSTKDREKEAELLASGDPQHAHFSGPLHVKVETVAPAYIAYGRVAAVIEELSRILQPIHEDTTPAHL 240

[Close]

BLAST of KHD-1 vs. Ensembl Celegans
Match: asd-2 (RNA-binding protein asd-2 [Source:UniProtKB/Swiss-Prot;Acc:G5EFF1])

HSP 1 Score: 82.0333 bits (201), Expect = 9.406e-17
Identity = 36/98 (36.73%), Postives = 62/98 (63.27%), Query Frame = 3

Query:  372 IPVEAYPNVNFVGKLLGPAGKTLKTVQEQTNTKMSILGSGSLRNPEKEQELLNSGDPKYNHLRDRLHLQIDSIGNPSEAYYNISYALAEVKKVMIPDP 665
            +P + +P+ NFVG++LGP G T K ++++T  K+ + G GS+R+ +KE+  LN G P + HL + LH+ I      + A   +  A+ EV+K+++P P
Sbjct:   94 VPAKEHPDYNFVGRILGPRGMTAKQLEQETGCKIMVRGRGSMRDKKKEE--LNRGKPNWEHLSEELHVLIQCEDTENRAKVKLMRAVEEVRKLLVPAP 189

[Close]

BLAST of KHD-1 vs. Ensembl Celegans
Match: asd-2 (RNA-binding protein asd-2 [Source:UniProtKB/Swiss-Prot;Acc:G5EFF1])

HSP 1 Score: 81.6481 bits (200), Expect = 2.455e-16
Identity = 36/98 (36.73%), Postives = 62/98 (63.27%), Query Frame = 3

Query:  372 IPVEAYPNVNFVGKLLGPAGKTLKTVQEQTNTKMSILGSGSLRNPEKEQELLNSGDPKYNHLRDRLHLQIDSIGNPSEAYYNISYALAEVKKVMIPDP 665
            +P + +P+ NFVG++LGP G T K ++++T  K+ + G GS+R+ +KE+  LN G P + HL + LH+ I      + A   +  A+ EV+K+++P P
Sbjct:   94 VPAKEHPDYNFVGRILGPRGMTAKQLEQETGCKIMVRGRGSMRDKKKEE--LNRGKPNWEHLSEELHVLIQCEDTENRAKVKLMRAVEEVRKLLVPAP 189

[Close]

BLAST of KHD-1 vs. Ensembl Celegans
Match: asd-2 (RNA-binding protein asd-2 [Source:UniProtKB/Swiss-Prot;Acc:G5EFF1])

HSP 1 Score: 80.8777 bits (198), Expect = 4.419e-16
Identity = 36/98 (36.73%), Postives = 62/98 (63.27%), Query Frame = 3

Query:  372 IPVEAYPNVNFVGKLLGPAGKTLKTVQEQTNTKMSILGSGSLRNPEKEQELLNSGDPKYNHLRDRLHLQIDSIGNPSEAYYNISYALAEVKKVMIPDP 665
            +P + +P+ NFVG++LGP G T K ++++T  K+ + G GS+R+ +KE+  LN G P + HL + LH+ I      + A   +  A+ EV+K+++P P
Sbjct:  136 VPAKEHPDYNFVGRILGPRGMTAKQLEQETGCKIMVRGRGSMRDKKKEE--LNRGKPNWEHLSEELHVLIQCEDTENRAKVKLMRAVEEVRKLLVPAP 231

[Close]

BLAST of KHD-1 vs. Ensembl Fly
Match: qkr58E-1 (gene:FBgn0022986 transcript:FBtr0339537)

HSP 1 Score: 118.242 bits (295), Expect = 8.301e-29
Identity = 52/100 (52.00%), Postives = 74/100 (74.00%), Query Frame = 3

Query:  372 IPVEAYPNVNFVGKLLGPAGKTLKTVQEQTNTKMSILGSGSLRNPEKEQELLNSGDPKYNHLRDRLHLQIDSIGNPSEAYYNISYALAEVKKVMIPDPNE 671
             P++ YP  NFVGK+LGP G TL+ +QE+T  KM ++G  S+R+  KE+EL +SG+PKY HL   LH++I ++  P+EAY+ ISYAL E++K MIPD N+
Sbjct:  119 FPIKEYPKFNFVGKILGPKGNTLRQLQEETMCKMVVMGRNSMRDHGKEEELRSSGNPKYAHLSRDLHVEISTVAPPAEAYHRISYALGEIRKFMIPDAND 218

[Close]

BLAST of KHD-1 vs. Ensembl Fly
Match: qkr58E-1 (gene:FBgn0022986 transcript:FBtr0346637)

HSP 1 Score: 117.857 bits (294), Expect = 1.348e-28
Identity = 52/100 (52.00%), Postives = 74/100 (74.00%), Query Frame = 3

Query:  372 IPVEAYPNVNFVGKLLGPAGKTLKTVQEQTNTKMSILGSGSLRNPEKEQELLNSGDPKYNHLRDRLHLQIDSIGNPSEAYYNISYALAEVKKVMIPDPNE 671
             P++ YP  NFVGK+LGP G TL+ +QE+T  KM ++G  S+R+  KE+EL +SG+PKY HL   LH++I ++  P+EAY+ ISYAL E++K MIPD N+
Sbjct:  119 FPIKEYPKFNFVGKILGPKGNTLRQLQEETMCKMVVMGRNSMRDHGKEEELRSSGNPKYAHLSRDLHVEISTVAPPAEAYHRISYALGEIRKFMIPDAND 218

[Close]

BLAST of KHD-1 vs. Ensembl Fly
Match: qkr58E-1 (gene:FBgn0022986 transcript:FBtr0071843)

HSP 1 Score: 118.242 bits (295), Expect = 1.510e-28
Identity = 52/100 (52.00%), Postives = 74/100 (74.00%), Query Frame = 3

Query:  372 IPVEAYPNVNFVGKLLGPAGKTLKTVQEQTNTKMSILGSGSLRNPEKEQELLNSGDPKYNHLRDRLHLQIDSIGNPSEAYYNISYALAEVKKVMIPDPNE 671
             P++ YP  NFVGK+LGP G TL+ +QE+T  KM ++G  S+R+  KE+EL +SG+PKY HL   LH++I ++  P+EAY+ ISYAL E++K MIPD N+
Sbjct:  119 FPIKEYPKFNFVGKILGPKGNTLRQLQEETMCKMVVMGRNSMRDHGKEEELRSSGNPKYAHLSRDLHVEISTVAPPAEAYHRISYALGEIRKFMIPDAND 218

[Close]

BLAST of KHD-1 vs. Ensembl Fly
Match: qkr58E-3 (gene:FBgn0022984 transcript:FBtr0339538)

HSP 1 Score: 112.464 bits (280), Expect = 4.223e-27
Identity = 46/101 (45.54%), Postives = 74/101 (73.27%), Query Frame = 3

Query:  372 IPVEAYPNVNFVGKLLGPAGKTLKTVQEQTNTKMSILGSGSLRNPEKEQELLNSGDPKYNHLRDRLHLQIDSIGNPSEAYYNISYALAEVKKVMIPDPNEQ 674
            +PV+ YP  NF GK+LGP G +L+ +QE+T  K++I G  S+R+  KE++L ++GDP+Y HL+  L L++ ++  P+E Y  I+YALAE++K +IPD N++
Sbjct:   86 VPVKQYPKFNFTGKILGPKGNSLRRLQEETQCKIAIKGRSSIRDRNKEEQLRSTGDPRYAHLQKDLFLEVSTVATPAECYARIAYALAEIRKYLIPDKNDE 186

[Close]

BLAST of KHD-1 vs. Ensembl Fly
Match: qkr58E-3 (gene:FBgn0022984 transcript:FBtr0307214)

HSP 1 Score: 112.464 bits (280), Expect = 4.223e-27
Identity = 46/101 (45.54%), Postives = 74/101 (73.27%), Query Frame = 3

Query:  372 IPVEAYPNVNFVGKLLGPAGKTLKTVQEQTNTKMSILGSGSLRNPEKEQELLNSGDPKYNHLRDRLHLQIDSIGNPSEAYYNISYALAEVKKVMIPDPNEQ 674
            +PV+ YP  NF GK+LGP G +L+ +QE+T  K++I G  S+R+  KE++L ++GDP+Y HL+  L L++ ++  P+E Y  I+YALAE++K +IPD N++
Sbjct:   86 VPVKQYPKFNFTGKILGPKGNSLRRLQEETQCKIAIKGRSSIRDRNKEEQLRSTGDPRYAHLQKDLFLEVSTVATPAECYARIAYALAEIRKYLIPDKNDE 186

[Close]

BLAST of KHD-1 vs. Ensembl Zebrafish
Match: khdrbs2 (KH domain containing, RNA binding, signal transduction associated 2 [Source:NCBI gene;Acc:768147])

HSP 1 Score: 116.316 bits (290), Expect = 4.437e-28
Identity = 54/101 (53.47%), Postives = 73/101 (72.28%), Query Frame = 3

Query:  372 IPVEAYPNVNFVGKLLGPAGKTLKTVQEQTNTKMSILGSGSLRNPEKEQELLNSGDPKYNHLRDRLHLQIDSIGNPSEAYYNISYALAEVKKVMIPDPNEQ 674
            IPV+ YP  NFVGKLLGP G ++K +QE+T  KMSILG GS+R+  KE+EL  SG+ KY HL + LH+ I+    P EAY  +S+AL E+KK ++PD N++
Sbjct:   66 IPVQQYPKFNFVGKLLGPRGNSMKRLQEETGAKMSILGKGSMRDKGKEEELRKSGEAKYAHLSNDLHVLIEVFAPPGEAYSRMSHALEEIKKFLVPDYNDE 166

[Close]

BLAST of KHD-1 vs. Ensembl Zebrafish
Match: KHDRBS3 (KH domain containing, RNA binding, signal transduction associated 3 [Source:NCBI gene;Acc:101867535])

HSP 1 Score: 107.842 bits (268), Expect = 1.349e-25
Identity = 52/92 (56.52%), Postives = 69/92 (75.00%), Query Frame = 3

Query:  399 NFVGKLLGPAGKTLKTVQEQTNTKMSILGSGSLRNPEKEQELLNSGDPKYNHLRDRLHLQIDSIGNPSEAYYNISYALAEVKKVMIPDPNEQ 674
            NFVGKLLGP G +LK +QE T TKMSILG GS+R+ EKE+EL  SG+ KY+HL + LH+ I+    P+EAY  + +AL E+KK +IPD N++
Sbjct:   25 NFVGKLLGPRGNSLKRLQEDTLTKMSILGKGSMRDKEKEEELRKSGETKYHHLNEDLHVLIEVFAPPAEAYARMGHALEEIKKFLIPDYNDE 116

[Close]

BLAST of KHD-1 vs. Ensembl Zebrafish
Match: khdrbs1b (KH domain containing, RNA binding, signal transduction associated 1b [Source:ZFIN;Acc:ZDB-GENE-040426-2344])

HSP 1 Score: 104.76 bits (260), Expect = 4.176e-24
Identity = 47/97 (48.45%), Postives = 68/97 (70.10%), Query Frame = 3

Query:  372 IPVEAYPNVNFVGKLLGPAGKTLKTVQEQTNTKMSILGSGSLRNPEKEQELLNSGDPKYNHLRDRLHLQIDSIGNPSEAYYNISYALAEVKKVMIPD 662
            IPV+ YP  NFVGK+LGP G T+K +QE+T  K+S+LG GS+R+  KE+EL  +G+PKY HL   LH+ I+      +AY  +++A+ E+KK + PD
Sbjct:   65 IPVKQYPKFNFVGKILGPQGNTIKRLQEETGAKISVLGKGSMRDKNKEEELRKNGEPKYAHLSMELHVFIEVFAPVPDAYMRMAHAMEEIKKFLFPD 161

[Close]

BLAST of KHD-1 vs. Ensembl Zebrafish
Match: khdrbs1a (KH domain containing, RNA binding, signal transduction associated 1a [Source:ZFIN;Acc:ZDB-GENE-000210-25])

HSP 1 Score: 103.605 bits (257), Expect = 1.857e-23
Identity = 47/96 (48.96%), Postives = 65/96 (67.71%), Query Frame = 3

Query:  372 IPVEAYPNVNFVGKLLGPAGKTLKTVQEQTNTKMSILGSGSLRNPEKEQELLNSGDPKYNHLRDRLHLQIDSIGNPSEAYYNISYALAEVKKVMIP 659
            IPV+ YP  NFVGK+LGP G T+K +QE T  K+S+LG GS+R+  KE+EL   GDPKY HL   LH+ I+      + Y  +++A+ EVKK ++P
Sbjct:   75 IPVKQYPRFNFVGKILGPQGSTIKRLQEDTGAKISVLGKGSMRDKNKEEELRKGGDPKYAHLGMELHVHIEVFAPIPDCYLRMAHAMDEVKKFLMP 170

[Close]

BLAST of KHD-1 vs. Ensembl Zebrafish
Match: khdrbs1a (KH domain containing, RNA binding, signal transduction associated 1a [Source:ZFIN;Acc:ZDB-GENE-000210-25])

HSP 1 Score: 102.834 bits (255), Expect = 2.449e-23
Identity = 47/96 (48.96%), Postives = 65/96 (67.71%), Query Frame = 3

Query:  372 IPVEAYPNVNFVGKLLGPAGKTLKTVQEQTNTKMSILGSGSLRNPEKEQELLNSGDPKYNHLRDRLHLQIDSIGNPSEAYYNISYALAEVKKVMIP 659
            IPV+ YP  NFVGK+LGP G T+K +QE T  K+S+LG GS+R+  KE+EL   GDPKY HL   LH+ I+      + Y  +++A+ EVKK ++P
Sbjct:   75 IPVKQYPRFNFVGKILGPQGSTIKRLQEDTGAKISVLGKGSMRDKNKEEELRKGGDPKYAHLGMELHVHIEVFAPIPDCYLRMAHAMDEVKKFLMP 170

[Close]

BLAST of KHD-1 vs. Ensembl Xenopus
Match: KHDRBS3 (KH domain containing, RNA binding, signal transduction associated 3 [Source:NCBI gene;Acc:100379996])

HSP 1 Score: 115.546 bits (288), Expect = 1.052e-27
Identity = 55/101 (54.46%), Postives = 73/101 (72.28%), Query Frame = 3

Query:  372 IPVEAYPNVNFVGKLLGPAGKTLKTVQEQTNTKMSILGSGSLRNPEKEQELLNSGDPKYNHLRDRLHLQIDSIGNPSEAYYNISYALAEVKKVMIPDPNEQ 674
            IP++ +P  NFVGKLLGP G +LK +QE T TKMSILG GS+R+  KE+EL  SG+ KY HL D LH+ I+    P+EAY  + +AL E+KK +IPD N++
Sbjct:   61 IPIKQFPKFNFVGKLLGPRGNSLKRLQEDTLTKMSILGKGSMRDKAKEEELRKSGEAKYYHLNDDLHVLIEVFAPPAEAYARMGHALEEIKKFLIPDYNDE 161

[Close]

BLAST of KHD-1 vs. Ensembl Xenopus
Match: pdc (phosducin [Source:Xenbase;Acc:XB-GENE-983832])

HSP 1 Score: 113.235 bits (282), Expect = 9.732e-27
Identity = 51/97 (52.58%), Postives = 71/97 (73.20%), Query Frame = 3

Query:  372 IPVEAYPNVNFVGKLLGPAGKTLKTVQEQTNTKMSILGSGSLRNPEKEQELLNSGDPKYNHLRDRLHLQIDSIGNPSEAYYNISYALAEVKKVMIPD 662
            IPV+ YP  NFVGK+LGP G T+K +QE+T  K+S+LG GS+R+  KE+EL   GDPKY+HL   LH+ I+  G P E+Y  +++A+ EVKK ++PD
Sbjct:   93 IPVKLYPKFNFVGKILGPQGNTIKRLQEETGAKISVLGKGSMRDKAKEEELRKGGDPKYSHLNMDLHVFIEVFGPPCESYTRMAHAMEEVKKFLVPD 189

[Close]

BLAST of KHD-1 vs. Ensembl Xenopus
Match: khdrbs2 (KH domain containing, RNA binding, signal transduction associated 2 [Source:NCBI gene;Acc:779662])

HSP 1 Score: 112.464 bits (280), Expect = 1.061e-26
Identity = 53/101 (52.48%), Postives = 72/101 (71.29%), Query Frame = 3

Query:  372 IPVEAYPNVNFVGKLLGPAGKTLKTVQEQTNTKMSILGSGSLRNPEKEQELLNSGDPKYNHLRDRLHLQIDSIGNPSEAYYNISYALAEVKKVMIPDPNEQ 674
            IPV+ YP  NFVGKLLGP G +LK +QE+T  KMSILG GS+R+  KE+EL  S + K+ HL D LH+ ++    P EAY  +S+AL E+KK ++PD N++
Sbjct:   66 IPVKQYPKFNFVGKLLGPRGNSLKRLQEETGAKMSILGKGSMRDKIKEEELRKSDEAKHAHLSDELHVLLEVFAPPGEAYSRMSHALEEIKKFLVPDYNDE 166

[Close]

BLAST of KHD-1 vs. Ensembl Xenopus
Match: pdc (phosducin [Source:Xenbase;Acc:XB-GENE-983832])

HSP 1 Score: 111.309 bits (277), Expect = 3.326e-26
Identity = 50/96 (52.08%), Postives = 70/96 (72.92%), Query Frame = 3

Query:  372 IPVEAYPNVNFVGKLLGPAGKTLKTVQEQTNTKMSILGSGSLRNPEKEQELLNSGDPKYNHLRDRLHLQIDSIGNPSEAYYNISYALAEVKKVMIP 659
            IPV+ YP  NFVGK+LGP G T+K +QE+T  K+S+LG GS+R+  KE+EL   GDPKY+HL   LH+ I+  G P E+Y  +++A+ EVKK ++P
Sbjct:   67 IPVKLYPKFNFVGKILGPQGNTIKRLQEETGAKISVLGKGSMRDKAKEEELRKGGDPKYSHLNMDLHVFIEVFGPPCESYTRMAHAMEEVKKFLVP 162

[Close]

BLAST of KHD-1 vs. Ensembl Xenopus
Match: spsb3 (splA/ryanodine receptor domain and SOCS box containing 3 [Source:Xenbase;Acc:XB-GENE-971062])

HSP 1 Score: 78.5666 bits (192), Expect = 2.033e-15
Identity = 37/96 (38.54%), Postives = 61/96 (63.54%), Query Frame = 3

Query:  372 IPVEAYPNVNFVGKLLGPAGKTLKTVQEQTNTKMSILGSGSLRNPEKEQELLNSGDPKYNHLRDRLHLQIDSIGNPSEAYYNISYALAEVKKVMIP 659
            +PV+ YP+ NFVG++LGP G T K ++ +T  K+ + G GS+R+ +KE++  N G P + HL + LH+ I      + A   +  A+ EVKK+++P
Sbjct:   89 VPVKEYPDFNFVGRILGPRGLTAKQLEAETGCKIMVRGKGSMRDKKKEEQ--NRGKPNWEHLNEDLHVLITVEDAQNRAEIKLKRAVEEVKKLLVP 182

[Close]

BLAST of KHD-1 vs. Ensembl Mouse
Match: Khdrbs3 (KH domain containing, RNA binding, signal transduction associated 3 [Source:MGI Symbol;Acc:MGI:1313312])

HSP 1 Score: 118.242 bits (295), Expect = 4.235e-31
Identity = 56/101 (55.45%), Postives = 74/101 (73.27%), Query Frame = 3

Query:  372 IPVEAYPNVNFVGKLLGPAGKTLKTVQEQTNTKMSILGSGSLRNPEKEQELLNSGDPKYNHLRDRLHLQIDSIGNPSEAYYNISYALAEVKKVMIPDPNEQ 674
            IPV+ +P  NFVGKLLGP G +LK +QE+T TKMSILG GS+R+  KE+EL  SG+ KY HL D LH+ I+    P+EAY  + +AL E+KK +IPD N++
Sbjct:    9 IPVKQFPKFNFVGKLLGPRGNSLKRLQEETLTKMSILGKGSMRDKAKEEELRKSGEAKYFHLNDDLHVLIEVFAPPAEAYARMGHALEEIKKFLIPDYNDE 109

[Close]

BLAST of KHD-1 vs. Ensembl Mouse
Match: Khdrbs2 (KH domain containing, RNA binding, signal transduction associated 2 [Source:MGI Symbol;Acc:MGI:2159649])

HSP 1 Score: 119.013 bits (297), Expect = 5.366e-29
Identity = 56/101 (55.45%), Postives = 73/101 (72.28%), Query Frame = 3

Query:  372 IPVEAYPNVNFVGKLLGPAGKTLKTVQEQTNTKMSILGSGSLRNPEKEQELLNSGDPKYNHLRDRLHLQIDSIGNPSEAYYNISYALAEVKKVMIPDPNEQ 674
            IPV+ YP  NFVGKLLGP G +LK +QE+T  KMSILG GS+R+  KE+EL  SG+ KY HL D LH+ I+    P EAY  +S+AL E+KK ++PD N++
Sbjct:   66 IPVKQYPKFNFVGKLLGPRGNSLKRLQEETGAKMSILGKGSMRDKTKEEELRKSGEAKYAHLSDELHVLIEVFAPPGEAYSRMSHALEEIKKFLVPDYNDE 166

[Close]

BLAST of KHD-1 vs. Ensembl Mouse
Match: Khdrbs3 (KH domain containing, RNA binding, signal transduction associated 3 [Source:MGI Symbol;Acc:MGI:1313312])

HSP 1 Score: 117.087 bits (292), Expect = 2.191e-28
Identity = 56/101 (55.45%), Postives = 74/101 (73.27%), Query Frame = 3

Query:  372 IPVEAYPNVNFVGKLLGPAGKTLKTVQEQTNTKMSILGSGSLRNPEKEQELLNSGDPKYNHLRDRLHLQIDSIGNPSEAYYNISYALAEVKKVMIPDPNEQ 674
            IPV+ +P  NFVGKLLGP G +LK +QE+T TKMSILG GS+R+  KE+EL  SG+ KY HL D LH+ I+    P+EAY  + +AL E+KK +IPD N++
Sbjct:   62 IPVKQFPKFNFVGKLLGPRGNSLKRLQEETLTKMSILGKGSMRDKAKEEELRKSGEAKYFHLNDDLHVLIEVFAPPAEAYARMGHALEEIKKFLIPDYNDE 162

[Close]

BLAST of KHD-1 vs. Ensembl Mouse
Match: Khdrbs3 (KH domain containing, RNA binding, signal transduction associated 3 [Source:MGI Symbol;Acc:MGI:1313312])

HSP 1 Score: 117.087 bits (292), Expect = 2.191e-28
Identity = 56/101 (55.45%), Postives = 74/101 (73.27%), Query Frame = 3

Query:  372 IPVEAYPNVNFVGKLLGPAGKTLKTVQEQTNTKMSILGSGSLRNPEKEQELLNSGDPKYNHLRDRLHLQIDSIGNPSEAYYNISYALAEVKKVMIPDPNEQ 674
            IPV+ +P  NFVGKLLGP G +LK +QE+T TKMSILG GS+R+  KE+EL  SG+ KY HL D LH+ I+    P+EAY  + +AL E+KK +IPD N++
Sbjct:   62 IPVKQFPKFNFVGKLLGPRGNSLKRLQEETLTKMSILGKGSMRDKAKEEELRKSGEAKYFHLNDDLHVLIEVFAPPAEAYARMGHALEEIKKFLIPDYNDE 162

[Close]

BLAST of KHD-1 vs. Ensembl Mouse
Match: Khdrbs3 (KH domain containing, RNA binding, signal transduction associated 3 [Source:MGI Symbol;Acc:MGI:1313312])

HSP 1 Score: 117.087 bits (292), Expect = 2.191e-28
Identity = 56/101 (55.45%), Postives = 74/101 (73.27%), Query Frame = 3

Query:  372 IPVEAYPNVNFVGKLLGPAGKTLKTVQEQTNTKMSILGSGSLRNPEKEQELLNSGDPKYNHLRDRLHLQIDSIGNPSEAYYNISYALAEVKKVMIPDPNEQ 674
            IPV+ +P  NFVGKLLGP G +LK +QE+T TKMSILG GS+R+  KE+EL  SG+ KY HL D LH+ I+    P+EAY  + +AL E+KK +IPD N++
Sbjct:   62 IPVKQFPKFNFVGKLLGPRGNSLKRLQEETLTKMSILGKGSMRDKAKEEELRKSGEAKYFHLNDDLHVLIEVFAPPAEAYARMGHALEEIKKFLIPDYNDE 162

[Close]

BLAST of KHD-1 vs. UniProt/SwissProt
Match: sp|Q920F3|KHDR2_RAT (KH domain-containing, RNA-binding, signal transduction-associated protein 2 OS=Rattus norvegicus OX=10116 GN=Khdrbs2 PE=1 SV=1)

HSP 1 Score: 119.783 bits (299), Expect = 2.182e-28
Identity = 56/101 (55.45%), Postives = 73/101 (72.28%), Query Frame = 3

Query:  372 IPVEAYPNVNFVGKLLGPAGKTLKTVQEQTNTKMSILGSGSLRNPEKEQELLNSGDPKYNHLRDRLHLQIDSIGNPSEAYYNISYALAEVKKVMIPDPNEQ 674
            IPV+ YP  NFVGKLLGP G +LK +QE+T  KMSILG GS+R+  KE+EL  SG+ KY HL D LH+ I+    P EAY  +S+AL E+KK ++PD N++
Sbjct:   66 IPVKQYPKFNFVGKLLGPRGNSLKRLQEETGAKMSILGKGSMRDKAKEEELRKSGEAKYAHLSDELHVLIEVFAPPGEAYSRMSHALEEIKKFLVPDYNDE 166

[Close]

BLAST of KHD-1 vs. UniProt/SwissProt
Match: sp|P13230|GRP33_ARTSA (Glycine-rich protein GRP33 OS=Artemia salina OX=85549 PE=2 SV=1)

HSP 1 Score: 118.242 bits (295), Expect = 2.864e-28
Identity = 55/101 (54.46%), Postives = 78/101 (77.23%), Query Frame = 3

Query:  372 IPVEAYPNVNFVGKLLGPAGKTLKTVQEQTNTKMSILGSGSLRNPEKEQELLNSGDPKYNHLRDRLHLQIDSIGNPSEAYYNISYALAEVKKVMIP--DPN 668
            +PV+ +P  NF+GKLLGP G T+K +Q++T TK+SILG GS+R+  KE+EL NSGD KY HL ++LH++I SI +P+EA+  ++YAL E+KK + P  DPN
Sbjct:   80 LPVDQFPKYNFLGKLLGPGGSTMKQLQDETMTKISILGRGSMRDRNKEEELRNSGDVKYAHLNEQLHIEIISIASPAEAHARMAYALTEIKKYITPEEDPN 180

[Close]

BLAST of KHD-1 vs. UniProt/SwissProt
Match: sp|Q5VWX1|KHDR2_HUMAN (KH domain-containing, RNA-binding, signal transduction-associated protein 2 OS=Homo sapiens OX=9606 GN=KHDRBS2 PE=1 SV=1)

HSP 1 Score: 119.398 bits (298), Expect = 2.890e-28
Identity = 56/101 (55.45%), Postives = 73/101 (72.28%), Query Frame = 3

Query:  372 IPVEAYPNVNFVGKLLGPAGKTLKTVQEQTNTKMSILGSGSLRNPEKEQELLNSGDPKYNHLRDRLHLQIDSIGNPSEAYYNISYALAEVKKVMIPDPNEQ 674
            IPV+ YP  NFVGKLLGP G +LK +QE+T  KMSILG GS+R+  KE+EL  SG+ KY HL D LH+ I+    P EAY  +S+AL E+KK ++PD N++
Sbjct:   66 IPVKQYPKFNFVGKLLGPRGNSLKRLQEETGAKMSILGKGSMRDKAKEEELRKSGEAKYAHLSDELHVLIEVFAPPGEAYSRMSHALEEIKKFLVPDYNDE 166

[Close]

BLAST of KHD-1 vs. UniProt/SwissProt
Match: sp|Q9WU01|KHDR2_MOUSE (KH domain-containing, RNA-binding, signal transduction-associated protein 2 OS=Mus musculus OX=10090 GN=Khdrbs2 PE=1 SV=1)

HSP 1 Score: 119.013 bits (297), Expect = 3.753e-28
Identity = 56/101 (55.45%), Postives = 73/101 (72.28%), Query Frame = 3

Query:  372 IPVEAYPNVNFVGKLLGPAGKTLKTVQEQTNTKMSILGSGSLRNPEKEQELLNSGDPKYNHLRDRLHLQIDSIGNPSEAYYNISYALAEVKKVMIPDPNEQ 674
            IPV+ YP  NFVGKLLGP G +LK +QE+T  KMSILG GS+R+  KE+EL  SG+ KY HL D LH+ I+    P EAY  +S+AL E+KK ++PD N++
Sbjct:   66 IPVKQYPKFNFVGKLLGPRGNSLKRLQEETGAKMSILGKGSMRDKTKEEELRKSGEAKYAHLSDELHVLIEVFAPPGEAYSRMSHALEEIKKFLVPDYNDE 166

[Close]

BLAST of KHD-1 vs. UniProt/SwissProt
Match: sp|Q9R226|KHDR3_MOUSE (KH domain-containing, RNA-binding, signal transduction-associated protein 3 OS=Mus musculus OX=10090 GN=Khdrbs3 PE=1 SV=1)

HSP 1 Score: 117.087 bits (292), Expect = 1.533e-27
Identity = 56/101 (55.45%), Postives = 74/101 (73.27%), Query Frame = 3

Query:  372 IPVEAYPNVNFVGKLLGPAGKTLKTVQEQTNTKMSILGSGSLRNPEKEQELLNSGDPKYNHLRDRLHLQIDSIGNPSEAYYNISYALAEVKKVMIPDPNEQ 674
            IPV+ +P  NFVGKLLGP G +LK +QE+T TKMSILG GS+R+  KE+EL  SG+ KY HL D LH+ I+    P+EAY  + +AL E+KK +IPD N++
Sbjct:   62 IPVKQFPKFNFVGKLLGPRGNSLKRLQEETLTKMSILGKGSMRDKAKEEELRKSGEAKYFHLNDDLHVLIEVFAPPAEAYARMGHALEEIKKFLIPDYNDE 162

[Close]

BLAST of KHD-1 vs. TrEMBL
Match: H9CXT9 (KHD-1 OS=Schmidtea mediterranea OX=79327 PE=2 SV=1)

HSP 1 Score: 366.311 bits (939), Expect = 2.986e-120
Identity = 306/306 (100.00%), Postives = 306/306 (100.00%), Query Frame = 3

Query:   87 MDGQSQDYTXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXGLIDAYENELHGVDEATCPNIAMLVRNELFRLRGGXXXXXXXXXXXXXXXXXXXXIPVEAYPNVNFVGKLLGPAGKTLKTVQEQTNTKMSILGSGSLRNPEKEQELLNSGDPKYNHLRDRLHLQIDSIGNPSEAYYNISYALAEVKKVMIPDPNEQAPGQMPMVTPLMXXXXXXXXXMXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXINNFNPMFMNGANDTGFTDDYPTMGFDNSFESXXXXXXXXXXXXXXXXXXNAPYSRPM 1004
            MDGQSQDYTQNADAQFQPAAQQNQQGNQQQQQPKRENQFQGLIDAYENELHGVDEATCPNIAMLVRNELFRLRGGVIDTVDVLTTKKTKVRTKVDIPVEAYPNVNFVGKLLGPAGKTLKTVQEQTNTKMSILGSGSLRNPEKEQELLNSGDPKYNHLRDRLHLQIDSIGNPSEAYYNISYALAEVKKVMIPDPNEQAPGQMPMVTPLMGGPNGGFGGMRNQPMNQQRGGRGRGGNRGSNRGGVGGPPRINNFNPMFMNGANDTGFTDDYPTMGFDNSFESGRGGGKMMRGGGMDRMNRNAPYSRPM
Sbjct:    1 MDGQSQDYTQNADAQFQPAAQQNQQGNQQQQQPKRENQFQGLIDAYENELHGVDEATCPNIAMLVRNELFRLRGGVIDTVDVLTTKKTKVRTKVDIPVEAYPNVNFVGKLLGPAGKTLKTVQEQTNTKMSILGSGSLRNPEKEQELLNSGDPKYNHLRDRLHLQIDSIGNPSEAYYNISYALAEVKKVMIPDPNEQAPGQMPMVTPLMGGPNGGFGGMRNQPMNQQRGGRGRGGNRGSNRGGVGGPPRINNFNPMFMNGANDTGFTDDYPTMGFDNSFESGRGGGKMMRGGGMDRMNRNAPYSRPM 306

[Close]

BLAST of KHD-1 vs. TrEMBL
Match: A0A4S2M594 (KH domain-containing protein OS=Opisthorchis felineus OX=147828 GN=CRM22_002587 PE=4 SV=1)

HSP 1 Score: 174.096 bits (440), Expect = 2.008e-46
Identity = 93/170 (54.71%), Postives = 125/170 (73.53%), Query Frame = 3

Query:  207 GLIDAYENELHGVDEATCPNIAMLVRNELFRLRGGXXXXXXXXXXXXXXXXXXXXIPVEAYPNVNFVGKLLGPAGKTLKTVQEQTNTKMSILGSGSLRNPEKEQELLNSGDPKYNHLRDRLHLQIDSIGNPSEAYYNISYALAEVKKVMIPDPNEQAP------GQMPMV 698
            G I+A   EL  +DE   P +  L  NELFRLRGG+ +++D+++ ++ K+R K++IP   YP VNFVGKLLGP G+TL+  QE T TKM+ILG+GSLR+  KE+ELL+SGDPKY HL+ +LHLQ+DS+  PSEAYY +S+ALAE++KVM+P+ NE  P      G  PMV
Sbjct:   13 GAIEAIVRELKNLDEKAFPALHALAENELFRLRGGIAESIDIVSNRQVKIRAKIEIPSSQYPGVNFVGKLLGPGGQTLRATQESTKTKMAILGAGSLRDDSKERELLSSGDPKYQHLKQKLHLQVDSLAPPSEAYYRLSHALAELRKVMLPESNECPPPPWVPQGTSPMV 182

[Close]

BLAST of KHD-1 vs. TrEMBL
Match: A0A4S2M597 (KH domain-containing protein OS=Opisthorchis felineus OX=147828 GN=CRM22_002587 PE=4 SV=1)

HSP 1 Score: 174.481 bits (441), Expect = 2.544e-46
Identity = 93/170 (54.71%), Postives = 125/170 (73.53%), Query Frame = 3

Query:  207 GLIDAYENELHGVDEATCPNIAMLVRNELFRLRGGXXXXXXXXXXXXXXXXXXXXIPVEAYPNVNFVGKLLGPAGKTLKTVQEQTNTKMSILGSGSLRNPEKEQELLNSGDPKYNHLRDRLHLQIDSIGNPSEAYYNISYALAEVKKVMIPDPNEQAP------GQMPMV 698
            G I+A   EL  +DE   P +  L  NELFRLRGG+ +++D+++ ++ K+R K++IP   YP VNFVGKLLGP G+TL+  QE T TKM+ILG+GSLR+  KE+ELL+SGDPKY HL+ +LHLQ+DS+  PSEAYY +S+ALAE++KVM+P+ NE  P      G  PMV
Sbjct:   13 GAIEAIVRELKNLDEKAFPALHALAENELFRLRGGIAESIDIVSNRQVKIRAKIEIPSSQYPGVNFVGKLLGPGGQTLRATQESTKTKMAILGAGSLRDDSKERELLSSGDPKYQHLKQKLHLQVDSLAPPSEAYYRLSHALAELRKVMLPESNECPPPPWVPQGTSPMV 182

[Close]

BLAST of KHD-1 vs. TrEMBL
Match: A0A564YXH5 (KH domain-containing protein OS=Hymenolepis diminuta OX=6216 GN=WMSIL1_LOCUS9986 PE=4 SV=1)

HSP 1 Score: 173.711 bits (439), Expect = 3.909e-46
Identity = 91/156 (58.33%), Postives = 121/156 (77.56%), Query Frame = 3

Query:  213 IDAYENELHGVDEATCPNIAMLVRNELFRLRGGXXXXXXXXXXXXXXXXXXXXIPVEAYPNVNFVGKLLGPAGKTLKTVQEQTNTKMSILGSGSLRNPEKEQELLNSGDPKYNHLRDRLHLQIDSIGNPSEAYYNISYALAEVKKVMIPDPNEQAP 680
            ++    E+  +DE T P +  +  NELFRLRGG+ DT+DV+  K+ K+R KV IPVE YP++NFVGKLLGP G TL+T+Q++T+TKM+ILG GSLR+  KE+ELL+ GDPKY HL+  LHLQID +  P++AYYNIS+ALA+VK+VM+PD N Q P
Sbjct:   14 VEVLSREVQNLDENTFPTLKSIGENELFRLRGGIADTLDVVDNKRVKIRAKVMIPVEQYPSINFVGKLLGPGGSTLRTIQDETHTKMAILGRGSLRDEAKEKELLSGGDPKYQHLKHPLHLQIDCLAPPADAYYNISHALAQVKRVMVPDANGQQP 169

[Close]

BLAST of KHD-1 vs. TrEMBL
Match: A0A4S2M5E9 (KH domain-containing protein OS=Opisthorchis felineus OX=147828 GN=CRM22_002587 PE=4 SV=1)

HSP 1 Score: 174.096 bits (440), Expect = 4.080e-46
Identity = 93/170 (54.71%), Postives = 125/170 (73.53%), Query Frame = 3

Query:  207 GLIDAYENELHGVDEATCPNIAMLVRNELFRLRGGXXXXXXXXXXXXXXXXXXXXIPVEAYPNVNFVGKLLGPAGKTLKTVQEQTNTKMSILGSGSLRNPEKEQELLNSGDPKYNHLRDRLHLQIDSIGNPSEAYYNISYALAEVKKVMIPDPNEQAP------GQMPMV 698
            G I+A   EL  +DE   P +  L  NELFRLRGG+ +++D+++ ++ K+R K++IP   YP VNFVGKLLGP G+TL+  QE T TKM+ILG+GSLR+  KE+ELL+SGDPKY HL+ +LHLQ+DS+  PSEAYY +S+ALAE++KVM+P+ NE  P      G  PMV
Sbjct:   13 GAIEAIVRELKNLDEKAFPALHALAENELFRLRGGIAESIDIVSNRQVKIRAKIEIPSSQYPGVNFVGKLLGPGGQTLRATQESTKTKMAILGAGSLRDDSKERELLSSGDPKYQHLKQKLHLQVDSLAPPSEAYYRLSHALAELRKVMLPESNECPPPPWVPQGTSPMV 182

[Close]

BLAST of KHD-1 vs. Ensembl Cavefish
Match: khdrbs2 (KH domain containing, RNA binding, signal transduction associated 2 [Source:NCBI gene;Acc:768147])

HSP 1 Score: 116.701 bits (291), Expect = 2.788e-28
Identity = 54/101 (53.47%), Postives = 73/101 (72.28%), Query Frame = 3

Query:  372 IPVEAYPNVNFVGKLLGPAGKTLKTVQEQTNTKMSILGSGSLRNPEKEQELLNSGDPKYNHLRDRLHLQIDSIGNPSEAYYNISYALAEVKKVMIPDPNEQ 674
            IPV+ YP  NFVGKLLGP G ++K +QE+T  KMSILG GS+R+  KE+EL  SG+ KY HL + LH+ I+    P EAY  +S+AL E+KK ++PD N++
Sbjct:   66 IPVQQYPKFNFVGKLLGPRGNSMKRLQEETGAKMSILGKGSMRDKGKEEELRKSGEAKYAHLSNDLHVLIEVFAPPGEAYSRMSHALEEIKKFLVPDYNDE 166

[Close]

BLAST of KHD-1 vs. Ensembl Cavefish
Match: khdrbs2 (KH domain containing, RNA binding, signal transduction associated 2 [Source:NCBI gene;Acc:768147])

HSP 1 Score: 117.087 bits (292), Expect = 4.016e-28
Identity = 54/101 (53.47%), Postives = 73/101 (72.28%), Query Frame = 3

Query:  372 IPVEAYPNVNFVGKLLGPAGKTLKTVQEQTNTKMSILGSGSLRNPEKEQELLNSGDPKYNHLRDRLHLQIDSIGNPSEAYYNISYALAEVKKVMIPDPNEQ 674
            IPV+ YP  NFVGKLLGP G ++K +QE+T  KMSILG GS+R+  KE+EL  SG+ KY HL + LH+ I+    P EAY  +S+AL E+KK ++PD N++
Sbjct:   66 IPVQQYPKFNFVGKLLGPRGNSMKRLQEETGAKMSILGKGSMRDKGKEEELRKSGEAKYAHLSNDLHVLIEVFAPPGEAYSRMSHALEEIKKFLVPDYNDE 166

[Close]

BLAST of KHD-1 vs. Ensembl Cavefish
Match: khdrbs2 (KH domain containing, RNA binding, signal transduction associated 2 [Source:NCBI gene;Acc:768147])

HSP 1 Score: 116.701 bits (291), Expect = 5.064e-28
Identity = 54/101 (53.47%), Postives = 73/101 (72.28%), Query Frame = 3

Query:  372 IPVEAYPNVNFVGKLLGPAGKTLKTVQEQTNTKMSILGSGSLRNPEKEQELLNSGDPKYNHLRDRLHLQIDSIGNPSEAYYNISYALAEVKKVMIPDPNEQ 674
            IPV+ YP  NFVGKLLGP G ++K +QE+T  KMSILG GS+R+  KE+EL  SG+ KY HL + LH+ I+    P EAY  +S+AL E+KK ++PD N++
Sbjct:   66 IPVQQYPKFNFVGKLLGPRGNSMKRLQEETGAKMSILGKGSMRDKGKEEELRKSGEAKYAHLSNDLHVLIEVFAPPGEAYSRMSHALEEIKKFLVPDYNDE 166

[Close]

BLAST of KHD-1 vs. Ensembl Cavefish
Match: khdrbs2 (KH domain containing, RNA binding, signal transduction associated 2 [Source:NCBI gene;Acc:768147])

HSP 1 Score: 117.087 bits (292), Expect = 9.260e-28
Identity = 54/101 (53.47%), Postives = 73/101 (72.28%), Query Frame = 3

Query:  372 IPVEAYPNVNFVGKLLGPAGKTLKTVQEQTNTKMSILGSGSLRNPEKEQELLNSGDPKYNHLRDRLHLQIDSIGNPSEAYYNISYALAEVKKVMIPDPNEQ 674
            IPV+ YP  NFVGKLLGP G ++K +QE+T  KMSILG GS+R+  KE+EL  SG+ KY HL + LH+ I+    P EAY  +S+AL E+KK ++PD N++
Sbjct:   66 IPVQQYPKFNFVGKLLGPRGNSMKRLQEETGAKMSILGKGSMRDKGKEEELRKSGEAKYAHLSNDLHVLIEVFAPPGEAYSRMSHALEEIKKFLVPDYNDE 166

[Close]

BLAST of KHD-1 vs. Ensembl Cavefish
Match: khdrbs2 (KH domain containing, RNA binding, signal transduction associated 2 [Source:NCBI gene;Acc:768147])

HSP 1 Score: 116.701 bits (291), Expect = 1.311e-27
Identity = 54/101 (53.47%), Postives = 73/101 (72.28%), Query Frame = 3

Query:  372 IPVEAYPNVNFVGKLLGPAGKTLKTVQEQTNTKMSILGSGSLRNPEKEQELLNSGDPKYNHLRDRLHLQIDSIGNPSEAYYNISYALAEVKKVMIPDPNEQ 674
            IPV+ YP  NFVGKLLGP G ++K +QE+T  KMSILG GS+R+  KE+EL  SG+ KY HL + LH+ I+    P EAY  +S+AL E+KK ++PD N++
Sbjct:   66 IPVQQYPKFNFVGKLLGPRGNSMKRLQEETGAKMSILGKGSMRDKGKEEELRKSGEAKYAHLSNDLHVLIEVFAPPGEAYSRMSHALEEIKKFLVPDYNDE 166

[Close]

BLAST of KHD-1 vs. Ensembl Sea Lamprey
Match: KHDRBS3 (KH RNA binding domain containing, signal transduction associated 3 [Source:HGNC Symbol;Acc:HGNC:18117])

HSP 1 Score: 112.079 bits (279), Expect = 4.191e-28
Identity = 52/105 (49.52%), Postives = 75/105 (71.43%), Query Frame = 3

Query:  372 IPVEAYPNVNFVGKLLGPAGKTLKTVQEQTNTKMSILGSGSLRNPEKEQELLNSGDPKYNHLRDRLHLQIDSIGNPSEAYYNISYALAEVKKVMIPDPNEQAPGQ 686
            IPV  +P  NF+GKLLGP G +LK ++E+T TK+SILG GS+R+ +KE++L  SG+ KY HL + LH+ I+    PS+AY  + +AL EVKK ++PD N++   Q
Sbjct:   43 IPVRQHPKFNFIGKLLGPRGNSLKRLKEETGTKLSILGKGSMRDRDKEEDLRKSGEAKYAHLNEDLHVLIEVFAPPSQAYRRMGHALDEVKKYLVPDYNDEIRQQ 147

[Close]

BLAST of KHD-1 vs. Ensembl Sea Lamprey
Match: khdrbs2 (KH domain containing, RNA binding, signal transduction associated 2 [Source:NCBI gene;Acc:768147])

HSP 1 Score: 111.694 bits (278), Expect = 2.308e-27
Identity = 53/101 (52.48%), Postives = 72/101 (71.29%), Query Frame = 3

Query:  372 IPVEAYPNVNFVGKLLGPAGKTLKTVQEQTNTKMSILGSGSLRNPEKEQELLNSGDPKYNHLRDRLHLQIDSIGNPSEAYYNISYALAEVKKVMIPDPNEQ 674
            IP + +P  NFVGKLLGP G +LK +QE+T TKMSILG GS+R+   E+E+  SG+ KY HL + LH+ I+    PSEAY  + +AL EVKK ++PD N++
Sbjct:   43 IPAKQHPKFNFVGKLLGPRGNSLKRMQEETGTKMSILGKGSMRDKALEEEMRKSGENKYAHLSEELHVLIEVFAPPSEAYSRMGHALDEVKKYLVPDYNDE 143

[Close]

BLAST of KHD-1 vs. Ensembl Sea Lamprey
Match: khdrbs1a (KH domain containing, RNA binding, signal transduction associated 1a [Source:ZFIN;Acc:ZDB-GENE-000210-25])

HSP 1 Score: 100.523 bits (249), Expect = 2.520e-23
Identity = 49/101 (48.51%), Postives = 68/101 (67.33%), Query Frame = 3

Query:  372 IPVEAYPNVNFVGKLLGPAGKTLKTVQEQTNTKMSILGSGSLRNPEKEQELLNSGDPKYNHLRDRLHLQIDSIGNPSEAYYNISYALAEVKKVMIPDPNEQ 674
            IP + +P  NFVGKLLGP G TLK +Q +T T+M+I+G G +++  KE+EL NSG+ KY HL + LH+ I+      EAY  + +AL EVKK   PD N++
Sbjct:   67 IPAKQHPKFNFVGKLLGPQGNTLKRLQVETGTRMAIMGKGCMKDRAKEEELRNSGEAKYVHLNEELHVLIEVYAPLPEAYSRMGHALEEVKKFFNPDYNDE 167

[Close]

BLAST of KHD-1 vs. Ensembl Sea Lamprey
Match: sf1 (splicing factor 1 [Source:ZFIN;Acc:ZDB-GENE-030131-2492])

HSP 1 Score: 48.1358 bits (113), Expect = 4.486e-6
Identity = 18/43 (41.86%), Postives = 32/43 (74.42%), Query Frame = 3

Query:  372 IPVEAYPNVNFVGKLLGPAGKTLKTVQEQTNTKMSILGSGSLR 500
            IP + +P++NF+G ++GP G TLK ++++ N K+ I G GS++
Sbjct:  212 IPQDEHPDINFIGLIIGPRGNTLKKIEKECNAKIMIRGKGSVK 254

[Close]

BLAST of KHD-1 vs. Ensembl Yeast
Match: MSL5 (Component of commitment complex; which defines first step in splicing pathway; essential protein that interacts with Mud2p and Prp40p, forming a bridge between the intron ends; also involved in nuclear retention of pre-mRNA; relocalizes to the cytosol in response to hypoxia [Source:SGD;Acc:S000004106])

HSP 1 Score: 58.9214 bits (141), Expect = 8.926e-10
Identity = 31/70 (44.29%), Postives = 44/70 (62.86%), Query Frame = 3

Query:  372 IPVEAYPNVNFVGKLLGPAGKTLKTVQEQTNTKMSILGSGSLRNPEKEQELLNSGDPKYNHLRDRLHLQI 581
            IPV+ YP+VNFVG LLGP G+TL+ +QE +N K++I G GS++  +   +L     P   +  D LH  I
Sbjct:  154 IPVDQYPDVNFVGLLLGPRGRTLRKLQEDSNCKIAIRGRGSVKEGKNASDL----PPGAMNFEDPLHCLI 219

[Close]

BLAST of KHD-1 vs. Ensembl Nematostella
Match: EDO44127 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RWI4])

HSP 1 Score: 106.686 bits (265), Expect = 5.698e-27
Identity = 51/101 (50.50%), Postives = 70/101 (69.31%), Query Frame = 3

Query:  372 IPVEAYPNVNFVGKLLGPAGKTLKTVQEQTNTKMSILGSGSLRNPEKEQELLNSGDPKYNHLRDRLHLQIDSIGNPSEAYYNISYALAEVKKVMIPDPNEQ 674
            IPV+ +P  NFVGKLLGP G T K +Q  T TKMSILG GS+R+ EKE+EL  + DPKY HL + LH+ I+    P +A+  +  A+ E+KK +IP+ N++
Sbjct:   55 IPVKDHPKFNFVGKLLGPRGNTFKRLQNSTGTKMSILGKGSMRDKEKEEELRATEDPKYAHLGEELHVLIEVEAPPGQAHARLGIAIEEIKKYLIPEMNDE 155

[Close]

BLAST of KHD-1 vs. Ensembl Nematostella
Match: EDO30297 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7T170])

HSP 1 Score: 67.0106 bits (162), Expect = 7.430e-13
Identity = 30/95 (31.58%), Postives = 53/95 (55.79%), Query Frame = 3

Query:  375 PVEAYPNVNFVGKLLGPAGKTLKTVQEQTNTKMSILGSGSLRNPEKEQELLNSGDPKYNHLRDRLHLQIDSIGNPSEAYYNISYALAEVKKVMIP 659
            PV+ +P  NFVG+++GP G TL+ ++  T  K+ + G GS+++ + E+E    G P Y HL + LH+ I         +  +  A+  V+ ++ P
Sbjct:   60 PVKEFPKFNFVGRVIGPRGMTLREIESTTGCKLLVRGKGSMKDKKLEEE--KRGQPNYEHLDEDLHVLISCEDTEERCHTRLEKAVERVQSLLRP 152

[Close]

BLAST of KHD-1 vs. Ensembl Nematostella
Match: EDO45484 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RSV9])

HSP 1 Score: 51.9878 bits (123), Expect = 1.765e-7
Identity = 25/60 (41.67%), Postives = 42/60 (70.00%), Query Frame = 3

Query:  372 IPVEAYPNVNFVGKLLGPAGKTLKTVQEQTNTKMSILGSGSLRNPE----KEQELLNSGD 539
            IP +  P VNF+G L+GP G TLK ++++TN K+ I G GS+++ +    ++ +L+NSG+
Sbjct:  186 IPQDENPEVNFIGLLIGPRGNTLKNMEKETNAKIMIRGKGSIKDGKQGRGRDMQLMNSGE 245

[Close]

BLAST of KHD-1 vs. Ensembl Nematostella
Match: EDO28641 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7T5W9])

HSP 1 Score: 46.595 bits (109), Expect = 3.388e-6
Identity = 17/43 (39.53%), Postives = 30/43 (69.77%), Query Frame = 3

Query:  375 PVEAYPNVNFVGKLLGPAGKTLKTVQEQTNTKMSILGSGSLRN 503
            PV+ +P  NFVG+++GP G TL+ ++  T  K+ + G GS+++
Sbjct:   99 PVKEFPKFNFVGRVIGPRGMTLREIESTTGCKLLVRGKGSMKD 141

[Close]

BLAST of KHD-1 vs. Ensembl Medaka
Match: khdrbs2 (KH RNA binding domain containing, signal transduction associated 2 [Source:NCBI gene;Acc:101155877])

HSP 1 Score: 119.013 bits (297), Expect = 3.674e-29
Identity = 55/101 (54.46%), Postives = 72/101 (71.29%), Query Frame = 3

Query:  372 IPVEAYPNVNFVGKLLGPAGKTLKTVQEQTNTKMSILGSGSLRNPEKEQELLNSGDPKYNHLRDRLHLQIDSIGNPSEAYYNISYALAEVKKVMIPDPNEQ 674
            IPV  YP  NFVGKLLGP G ++K +QE+T  KMSILG GS+R+ EKE+EL   GD KY HL + LH+ I+    P EAY  +S+AL E+KK ++PD N++
Sbjct:   69 IPVRQYPKFNFVGKLLGPRGNSMKRLQEETGVKMSILGKGSMRDKEKEEELRKGGDAKYAHLSNDLHVLIEVFAPPGEAYSRMSHALEEIKKFLVPDYNDE 169

[Close]

BLAST of KHD-1 vs. Ensembl Medaka
Match: khdrbs2 (KH RNA binding domain containing, signal transduction associated 2 [Source:NCBI gene;Acc:101155877])

HSP 1 Score: 118.627 bits (296), Expect = 4.934e-29
Identity = 55/101 (54.46%), Postives = 72/101 (71.29%), Query Frame = 3

Query:  372 IPVEAYPNVNFVGKLLGPAGKTLKTVQEQTNTKMSILGSGSLRNPEKEQELLNSGDPKYNHLRDRLHLQIDSIGNPSEAYYNISYALAEVKKVMIPDPNEQ 674
            IPV  YP  NFVGKLLGP G ++K +QE+T  KMSILG GS+R+ EKE+EL   GD KY HL + LH+ I+    P EAY  +S+AL E+KK ++PD N++
Sbjct:   66 IPVRQYPKFNFVGKLLGPRGNSMKRLQEETGVKMSILGKGSMRDKEKEEELRKGGDAKYAHLSNDLHVLIEVFAPPGEAYSRMSHALEEIKKFLVPDYNDE 166

[Close]

BLAST of KHD-1 vs. Ensembl Medaka
Match: KHDRBS3 (KH RNA binding domain containing, signal transduction associated 3 [Source:NCBI gene;Acc:101171680])

HSP 1 Score: 116.701 bits (291), Expect = 2.157e-28
Identity = 56/101 (55.45%), Postives = 74/101 (73.27%), Query Frame = 3

Query:  372 IPVEAYPNVNFVGKLLGPAGKTLKTVQEQTNTKMSILGSGSLRNPEKEQELLNSGDPKYNHLRDRLHLQIDSIGNPSEAYYNISYALAEVKKVMIPDPNEQ 674
            IPV+ +P  NFVGKLLGP G +LK +QE T TKMSILG GS+R+ EKE+EL  SG+ KY HL + LH+ I+    P+EAY  + +AL E+KK +IPD N++
Sbjct:   63 IPVKQFPKFNFVGKLLGPRGNSLKRLQEDTLTKMSILGKGSMRDKEKEEELRQSGEAKYQHLNEDLHVLIEVFAPPAEAYARMGHALEEIKKFLIPDYNDE 163

[Close]

BLAST of KHD-1 vs. Ensembl Medaka
Match: KHDRBS3 (KH RNA binding domain containing, signal transduction associated 3 [Source:NCBI gene;Acc:101171680])

HSP 1 Score: 116.701 bits (291), Expect = 2.397e-28
Identity = 56/101 (55.45%), Postives = 74/101 (73.27%), Query Frame = 3

Query:  372 IPVEAYPNVNFVGKLLGPAGKTLKTVQEQTNTKMSILGSGSLRNPEKEQELLNSGDPKYNHLRDRLHLQIDSIGNPSEAYYNISYALAEVKKVMIPDPNEQ 674
            IPV+ +P  NFVGKLLGP G +LK +QE T TKMSILG GS+R+ EKE+EL  SG+ KY HL + LH+ I+    P+EAY  + +AL E+KK +IPD N++
Sbjct:   63 IPVKQFPKFNFVGKLLGPRGNSLKRLQEDTLTKMSILGKGSMRDKEKEEELRQSGEAKYQHLNEDLHVLIEVFAPPAEAYARMGHALEEIKKFLIPDYNDE 163

[Close]

BLAST of KHD-1 vs. Ensembl Medaka
Match: khdrbs1a (KH domain-containing, RNA-binding, signal transduction-associated protein 1 [Source:NCBI gene;Acc:101175524])

HSP 1 Score: 110.923 bits (276), Expect = 3.680e-26
Identity = 52/103 (50.49%), Postives = 71/103 (68.93%), Query Frame = 3

Query:  372 IPVEAYPNVNFVGKLLGPAGKTLKTVQEQTNTKMSILGSGSLRNPEKEQELLNSGDPKYNHLRDRLHLQIDSIGNPSEAYYNISYALAEVKKVMIPDPNEQAP 680
            IP++ YP VNFVGKLLGP G T+K +QE+T  K+S+LG GS+R+  KE+EL   G+ KY HL   LH+ I+      EAY  +++A+ EVKK +IP+P E  P
Sbjct:   66 IPIKQYPRVNFVGKLLGPQGSTIKRLQEETGAKISVLGKGSMRDKNKEEELRKGGEAKYAHLAMELHVFIEVTAPIPEAYMRMAHAMDEVKKFLIPEPGEHEP 168

[Close]

BLAST of KHD-1 vs. Planmine SMEST
Match: SMESG000070471.1 (SMESG000070471.1)

HSP 1 Score: 366.311 bits (939), Expect = 8.305e-124
Identity = 306/306 (100.00%), Postives = 306/306 (100.00%), Query Frame = 3

Query:   87 MDGQSQDYTXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXGLIDAYENELHGVDEATCPNIAMLVRNELFRLRGGXXXXXXXXXXXXXXXXXXXXIPVEAYPNVNFVGKLLGPAGKTLKTVQEQTNTKMSILGSGSLRNPEKEQELLNSGDPKYNHLRDRLHLQIDSIGNPSEAYYNISYALAEVKKVMIPDPNEQAPGQMPMVTPLMXXXXXXXXXMXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXINNFNPMFMNGANDTGFTDDYPTMGFDNSFESXXXXXXXXXXXXXXXXXXNAPYSRPM 1004
            MDGQSQDYTQNADAQFQPAAQQNQQGNQQQQQPKRENQFQGLIDAYENELHGVDEATCPNIAMLVRNELFRLRGGVIDTVDVLTTKKTKVRTKVDIPVEAYPNVNFVGKLLGPAGKTLKTVQEQTNTKMSILGSGSLRNPEKEQELLNSGDPKYNHLRDRLHLQIDSIGNPSEAYYNISYALAEVKKVMIPDPNEQAPGQMPMVTPLMGGPNGGFGGMRNQPMNQQRGGRGRGGNRGSNRGGVGGPPRINNFNPMFMNGANDTGFTDDYPTMGFDNSFESGRGGGKMMRGGGMDRMNRNAPYSRPM
Sbjct:    1 MDGQSQDYTQNADAQFQPAAQQNQQGNQQQQQPKRENQFQGLIDAYENELHGVDEATCPNIAMLVRNELFRLRGGVIDTVDVLTTKKTKVRTKVDIPVEAYPNVNFVGKLLGPAGKTLKTVQEQTNTKMSILGSGSLRNPEKEQELLNSGDPKYNHLRDRLHLQIDSIGNPSEAYYNISYALAEVKKVMIPDPNEQAPGQMPMVTPLMGGPNGGFGGMRNQPMNQQRGGRGRGGNRGSNRGGVGGPPRINNFNPMFMNGANDTGFTDDYPTMGFDNSFESGRGGGKMMRGGGMDRMNRNAPYSRPM 306

[Close]

BLAST of KHD-1 vs. Planmine SMEST
Match: SMESG000004103.1 (SMESG000004103.1)

HSP 1 Score: 166.007 bits (419), Expect = 5.285e-47
Identity = 91/155 (58.71%), Postives = 117/155 (75.48%), Query Frame = 3

Query:  207 GLIDAYENELHGVDEATCPNIAMLVRNELFRLRGGXXXXXXXXXXXXXXXXXXXXIPVEAYPNVNFVGKLLGPAGKTLKTVQEQTNTKMSILGSGSLRNPEKEQELLNSGDPKYNHLRDRLHLQIDSIGNPSEAYYNISYALAEVKKVMIPDPNE 671
             LI+AYE EL  +D   CPN+   +R E+ RLR G+IDT+D L+ KK K+RTK+D PVE YP VNF GK++GP GKTLK +QEQT T+MS+LG+GS+RN  KE EL+ +GDPKY HL +R+HLQ+D +  PSEAY  IS AL E+KK + PDP+E
Sbjct:   13 ALIEAYEQELLTIDAVACPNVHSQIRMEIRRLREGIIDTIDTLSNKKVKIRTKIDFPVEQYPGVNFPGKIIGPGGKTLKELQEQTETRMSVLGAGSMRNRNKEMELIQTGDPKYQHLNERMHLQVDCLALPSEAYEKISKALIEIKKALTPDPSE 167

[Close]

BLAST of KHD-1 vs. Planmine SMEST
Match: SMESG000057199.1 (SMESG000057199.1)

HSP 1 Score: 126.716 bits (317), Expect = 5.512e-33
Identity = 80/147 (54.42%), Postives = 102/147 (69.39%), Query Frame = 3

Query:  213 IDAYENELHGVDEATCPNIAMLVRNELFRLRGGXXXXXXXXXXXXXXXXXXXXIPVEAYPNVNFVGKLLGPAGKTLKTVQEQTNTKMSILGSGSLRNPEKEQELLNSGDPKYNHLRDRLHLQIDSIGNPSEAYYNISYALAEVKKVM 653
            ID  E EL  +D+   P +A L   EL RLRGG+ D+VD+ + KK K+R KV IPV+ YP+VNFVGKLLGP   TLK +Q QTNTKM+ILG G L+N  K++E  N  D K    + +LHLQIDS+G P+EAYY +S+AL EV+  M
Sbjct:   16 IDILEQELKEIDDKY-PYLASLGEAELHRLRGGIADSVDLFSNKKVKIRAKVHIPVDQYPSVNFVGKLLGPGASTLKGIQGQTNTKMTILGVGVLKN--KKEEFQNKIDKKNISTKQKLHLQIDSLGTPAEAYYRLSHALVEVQNCM 159

[Close]

BLAST of KHD-1 vs. Planmine SMEST
Match: SMESG000057199.1 (SMESG000057199.1)

HSP 1 Score: 126.716 bits (317), Expect = 6.370e-33
Identity = 80/147 (54.42%), Postives = 102/147 (69.39%), Query Frame = 3

Query:  213 IDAYENELHGVDEATCPNIAMLVRNELFRLRGGXXXXXXXXXXXXXXXXXXXXIPVEAYPNVNFVGKLLGPAGKTLKTVQEQTNTKMSILGSGSLRNPEKEQELLNSGDPKYNHLRDRLHLQIDSIGNPSEAYYNISYALAEVKKVM 653
            ID  E EL  +D+   P +A L   EL RLRGG+ D+VD+ + KK K+R KV IPV+ YP+VNFVGKLLGP   TLK +Q QTNTKM+ILG G L+N  K++E  N  D K    + +LHLQIDS+G P+EAYY +S+AL EV+  M
Sbjct:   16 IDILEQELKEIDDK-YPYLASLGEAELHRLRGGIADSVDLFSNKKVKIRAKVHIPVDQYPSVNFVGKLLGPGASTLKGIQGQTNTKMTILGVGVLKN--KKEEFQNKIDKKNISTKQKLHLQIDSLGTPAEAYYRLSHALVEVQNCM 159

[Close]

BLAST of KHD-1 vs. Planmine SMEST
Match: SMESG000057199.1 (SMESG000057199.1)

HSP 1 Score: 123.635 bits (309), Expect = 6.604e-32
Identity = 80/147 (54.42%), Postives = 102/147 (69.39%), Query Frame = 3

Query:  213 IDAYENELHGVDEATCPNIAMLVRNELFRLRGGXXXXXXXXXXXXXXXXXXXXIPVEAYPNVNFVGKLLGPAGKTLKTVQEQTNTKMSILGSGSLRNPEKEQELLNSGDPKYNHLRDRLHLQIDSIGNPSEAYYNISYALAEVKKVM 653
            ID  E EL  +D+   P +A L   EL RLRGG+ D+VD+ + KK K+R KV IPV+ YP+VNFVGKLLGP   TLK +Q QTNTKM+ILG G L+N  K++E  N  D K    + +LHLQIDS+G P+EAYY +S+AL EV+  M
Sbjct:   16 IDILEQELKEIDDKY-PYLASL---ELHRLRGGIADSVDLFSNKKVKIRAKVHIPVDQYPSVNFVGKLLGPGASTLKGIQGQTNTKMTILGVGVLKN--KKEEFQNKIDKKNISTKQKLHLQIDSLGTPAEAYYRLSHALVEVQNCM 156

The following BLAST results are available for this feature:

BLAST of KHD-1 vs. Ensembl Human
BLAST of KHD-1 vs. Ensembl Celegans
BLAST of KHD-1 vs. Ensembl Fly
BLAST of KHD-1 vs. Ensembl Zebrafish
BLAST of KHD-1 vs. Ensembl Xenopus
BLAST of KHD-1 vs. Ensembl Mouse
BLAST of KHD-1 vs. UniProt/SwissProt
BLAST of KHD-1 vs. TrEMBL
BLAST of KHD-1 vs. Ensembl Cavefish
BLAST of KHD-1 vs. Ensembl Sea Lamprey
BLAST of KHD-1 vs. Ensembl Yeast
BLAST of KHD-1 vs. Ensembl Nematostella
BLAST of KHD-1 vs. Ensembl Medaka
BLAST of KHD-1 vs. Planmine SMEST

BLAST of KHD-1 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5


Match Name	E-value	Identity	Description
KHDRBS3	2.046e-30	55.45	KH RNA binding domain containing, signal transduct...	[more]
KHDRBS2	6.018e-29	55.45	KH RNA binding domain containing, signal transduct...	[more]
KHDRBS3	7.762e-29	55.45	KH RNA binding domain containing, signal transduct...	[more]
KHDRBS3	4.432e-28	55.45	KH RNA binding domain containing, signal transduct...	[more]
KHDRBS1	4.883e-26	53.61	KH RNA binding domain containing, signal transduct...	[more]

BLAST of KHD-1 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 5


Match Name	E-value	Identity	Description
E02D9.1	7.596e-18	34.91	pep chromosome:WBcel235:I:6800386:6803841:1 gene:W...	[more]
E02D9.1	7.753e-18	34.91	pep chromosome:WBcel235:I:6800386:6801970:1 gene:W...	[more]
asd-2	9.406e-17	36.73	RNA-binding protein asd-2 [Source:UniProtKB/Swiss...	[more]
asd-2	2.455e-16	36.73	RNA-binding protein asd-2 [Source:UniProtKB/Swiss...	[more]
asd-2	4.419e-16	36.73	RNA-binding protein asd-2 [Source:UniProtKB/Swiss...	[more]

BLAST of KHD-1 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5


Match Name	E-value	Identity	Description
qkr58E-1	8.301e-29	52.00	gene:FBgn0022986 transcript:FBtr0339537	[more]
qkr58E-1	1.348e-28	52.00	gene:FBgn0022986 transcript:FBtr0346637	[more]
qkr58E-1	1.510e-28	52.00	gene:FBgn0022986 transcript:FBtr0071843	[more]
qkr58E-3	4.223e-27	45.54	gene:FBgn0022984 transcript:FBtr0339538	[more]
qkr58E-3	4.223e-27	45.54	gene:FBgn0022984 transcript:FBtr0307214	[more]

BLAST of KHD-1 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5


Match Name	E-value	Identity	Description
khdrbs2	4.437e-28	53.47	KH domain containing, RNA binding, signal transduc...	[more]
KHDRBS3	1.349e-25	56.52	KH domain containing, RNA binding, signal transduc...	[more]
khdrbs1b	4.176e-24	48.45	KH domain containing, RNA binding, signal transduc...	[more]
khdrbs1a	1.857e-23	48.96	KH domain containing, RNA binding, signal transduc...	[more]
khdrbs1a	2.449e-23	48.96	KH domain containing, RNA binding, signal transduc...	[more]

BLAST of KHD-1 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5


Match Name	E-value	Identity	Description
KHDRBS3	1.052e-27	54.46	KH domain containing, RNA binding, signal transduc...	[more]
pdc	9.732e-27	52.58	phosducin [Source:Xenbase;Acc:XB-GENE-983832]	[more]
khdrbs2	1.061e-26	52.48	KH domain containing, RNA binding, signal transduc...	[more]
pdc	3.326e-26	52.08	phosducin [Source:Xenbase;Acc:XB-GENE-983832]	[more]
spsb3	2.033e-15	38.54	splA/ryanodine receptor domain and SOCS box contai...	[more]

BLAST of KHD-1 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5


Match Name	E-value	Identity	Description
Khdrbs3	4.235e-31	55.45	KH domain containing, RNA binding, signal transduc...	[more]
Khdrbs2	5.366e-29	55.45	KH domain containing, RNA binding, signal transduc...	[more]
Khdrbs3	2.191e-28	55.45	KH domain containing, RNA binding, signal transduc...	[more]
Khdrbs3	2.191e-28	55.45	KH domain containing, RNA binding, signal transduc...	[more]
Khdrbs3	2.191e-28	55.45	KH domain containing, RNA binding, signal transduc...	[more]

BLAST of KHD-1 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5


Match Name	E-value	Identity	Description
sp\|Q920F3\|KHDR2_RAT	2.182e-28	55.45	KH domain-containing, RNA-binding, signal transduc...	[more]
sp\|P13230\|GRP33_ARTSA	2.864e-28	54.46	Glycine-rich protein GRP33 OS=Artemia salina OX=85...	[more]
sp\|Q5VWX1\|KHDR2_HUMAN	2.890e-28	55.45	KH domain-containing, RNA-binding, signal transduc...	[more]
sp\|Q9WU01\|KHDR2_MOUSE	3.753e-28	55.45	KH domain-containing, RNA-binding, signal transduc...	[more]
sp\|Q9R226\|KHDR3_MOUSE	1.533e-27	55.45	KH domain-containing, RNA-binding, signal transduc...	[more]

BLAST of KHD-1 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5


Match Name	E-value	Identity	Description
H9CXT9	2.986e-120	100.00	KHD-1 OS=Schmidtea mediterranea OX=79327 PE=2 SV=1	[more]
A0A4S2M594	2.008e-46	54.71	KH domain-containing protein OS=Opisthorchis felin...	[more]
A0A4S2M597	2.544e-46	54.71	KH domain-containing protein OS=Opisthorchis felin...	[more]
A0A564YXH5	3.909e-46	58.33	KH domain-containing protein OS=Hymenolepis diminu...	[more]
A0A4S2M5E9	4.080e-46	54.71	KH domain-containing protein OS=Opisthorchis felin...	[more]

BLAST of KHD-1 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5


Match Name	E-value	Identity	Description
khdrbs2	2.788e-28	53.47	KH domain containing, RNA binding, signal transduc...	[more]
khdrbs2	4.016e-28	53.47	KH domain containing, RNA binding, signal transduc...	[more]
khdrbs2	5.064e-28	53.47	KH domain containing, RNA binding, signal transduc...	[more]
khdrbs2	9.260e-28	53.47	KH domain containing, RNA binding, signal transduc...	[more]
khdrbs2	1.311e-27	53.47	KH domain containing, RNA binding, signal transduc...	[more]

BLAST of KHD-1 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 4


Match Name	E-value	Identity	Description
KHDRBS3	4.191e-28	49.52	KH RNA binding domain containing, signal transduct...	[more]
khdrbs2	2.308e-27	52.48	KH domain containing, RNA binding, signal transduc...	[more]
khdrbs1a	2.520e-23	48.51	KH domain containing, RNA binding, signal transduc...	[more]
sf1	4.486e-6	41.86	splicing factor 1 [Source:ZFIN;Acc:ZDB-GENE-030131...	[more]

BLAST of KHD-1 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 1


Match Name	E-value	Identity	Description
MSL5	8.926e-10	44.29	Component of commitment complex; which defines fir...	[more]

BLAST of KHD-1 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 4


Match Name	E-value	Identity	Description
EDO44127	5.698e-27	50.50	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO30297	7.430e-13	31.58	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO45484	1.765e-7	41.67	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO28641	3.388e-6	39.53	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]

BLAST of KHD-1 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5


Match Name	E-value	Identity	Description
khdrbs2	3.674e-29	54.46	KH RNA binding domain containing, signal transduct...	[more]
khdrbs2	4.934e-29	54.46	KH RNA binding domain containing, signal transduct...	[more]
KHDRBS3	2.157e-28	55.45	KH RNA binding domain containing, signal transduct...	[more]
KHDRBS3	2.397e-28	55.45	KH RNA binding domain containing, signal transduct...	[more]
khdrbs1a	3.680e-26	50.49	KH domain-containing, RNA-binding, signal transduc...	[more]

BLAST of KHD-1 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5


Match Name	E-value	Identity	Description
SMESG000070471.1	8.305e-124	100.00	SMESG000070471.1	[more]
SMESG000004103.1	5.285e-47	58.71	SMESG000004103.1	[more]
SMESG000057199.1	5.512e-33	54.42	SMESG000057199.1	[more]
SMESG000057199.1	6.370e-33	54.42	SMESG000057199.1	[more]
SMESG000057199.1	6.604e-32	54.42	SMESG000057199.1	[more]

Analyses

This transcript is derived from or has results from the following analyses


Analysis Name	Date Performed
Embryonic Stages	2016-07-25
Schmidtea mediterranea smed_20140614 BLASTX Human e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL	2020-05-01
Schmidtea mediterranea Sexual smed_20140614 transcriptome	2016-07-25
Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST	2020-05-08

Cross References

External references for this transcript


Database	Accession
SmedGD GBrowse	SMED30013157
GenBank	AFD29610.1

Sequences

The following sequences are available for this feature:

transcript sequence
protein sequence

transcript sequence

>SMED30013157 ID=SMED30013157|Name=KHD-1|organism=Schmidtea mediterranea sexual|type=transcript|length=1677bp
TTCAAAATAAGTTTTAAAATATTTTGTTTAAAAGCATTACTTTATTTATT
TCAACGTGAAAGTTTTGGTTTCATATTCTTTTCAAAATGGATGGTCAAAG
TCAAGATTATACCCAAAATGCTGATGCGCAATTTCAACCTGCAGCACAAC
AAAATCAACAAGGTAATCAACAACAACAACAACCTAAACGTGAAAATCAA
TTCCAAGGACTAATTGATGCCTATGAAAATGAATTACATGGAGTTGATGA
AGCAACTTGCCCAAATATCGCCATGCTTGTTCGAAATGAACTTTTTAGAC
TTCGTGGAGGAGTTATTGATACTGTCGATGTACTAACTACTAAGAAAACT
AAAGTGCGTACAAAAGTTGATATTCCAGTTGAAGCATACCCAAATGTTAA
CTTTGTTGGAAAACTTTTGGGCCCAGCTGGTAAAACTCTAAAAACAGTTC
AAGAGCAAACTAACACTAAAATGTCAATATTGGGATCCGGTTCTTTAAGA
AATCCAGAAAAAGAACAGGAATTGTTAAACTCTGGTGATCCTAAATACAA
TCACTTGCGAGATCGTTTACATTTGCAAATCGATTCCATTGGCAATCCGT
CTGAAGCTTATTATAATATATCTTATGCACTAGCTGAAGTTAAAAAGGTC
ATGATTCCCGATCCTAACGAACAAGCTCCAGGGCAAATGCCAATGGTTAC
ACCTTTAATGGGAGGTCCTAATGGTGGTTTTGGTGGAATGAGAAATCAAC
CGATGAACCAACAACGAGGCGGTAGAGGTCGTGGAGGTAATCGAGGATCA
AATAGGGGTGGTGTTGGAGGTCCCCCAAGAATTAACAATTTTAACCCAAT
GTTTATGAATGGTGCAAATGACACCGGATTTACTGATGATTATCCAACCA
TGGGATTTGATAATAGTTTTGAATCGGGACGAGGAGGCGGGAAAATGATG
CGAGGTGGTGGTATGGATAGAATGAATCGAAATGCACCGTATTCTCGACC
CATGTGAAACATTCATTAACGTAGGTGCTGCTTTGTTAAAATAGCATCTA
TTTATCAAAAATGCATTTCATATTGACTTTAGAATATCGTATTGAAAAAT
CCAAAAAAAATCAAAACATTCAATGATAATAAGTATTTGTTAAACTCGTC
AATAGCAGCATGATTGTTAAAATTTGTATTTAATAATAAAATTTATATTC
ATGTATAAAATCGTTATTTAATTTTAATTTAATTACTTCAGCAAATTATT
TTAATATTTGAAATTTATTTTGATAATCTATGATGTTTGAGCACTGAGAG
CGGAAAAATGATTTTAATAACTGCGACAAAATATTTAAAATTCCAAATTT
CAGAAAACTAAACGAAAAATCTTTTCTAAAAAGTGGGTGAGTTATTAAAA
TTTAAATGTAGTGTAAATTTCATACTAATAACACATTTTTATGCTATTAT
CATTTTATTATTGCAGATTTTTGACTTGGACGGTTATGAAAACAATGGGG
AATGTTTGGACTTAGAAAAGATTGAGTAAGTCGTTAACTTAGAGATTAAG
TGGCCTTAATTCTCTATTACTCATCTAATGTTTATGTTTCTGAGACATGT
TAGTATTACATAACCCAATTGATTATTATTTTTGATAATATTGTGTTTAT
TTAAATAAATTTATTTGTTGAAAAAAA

protein sequence of SMED30013157-orf-1

>SMED30013157-orf-1 ID=SMED30013157-orf-1|Name=SMED30013157-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=307bp
MDGQSQDYTQNADAQFQPAAQQNQQGNQQQQQPKRENQFQGLIDAYENEL
HGVDEATCPNIAMLVRNELFRLRGGVIDTVDVLTTKKTKVRTKVDIPVEA
YPNVNFVGKLLGPAGKTLKTVQEQTNTKMSILGSGSLRNPEKEQELLNSG
DPKYNHLRDRLHLQIDSIGNPSEAYYNISYALAEVKKVMIPDPNEQAPGQ
MPMVTPLMGGPNGGFGGMRNQPMNQQRGGRGRGGNRGSNRGGVGGPPRIN
NFNPMFMNGANDTGFTDDYPTMGFDNSFESGRGGGKMMRGGGMDRMNRNA
PYSRPM*

Annotated Terms

The following terms have been associated with this transcript:

Vocabulary: **cellular component**
Term	Definition
GO:0016020	membrane
GO:0016021	integral component of membrane

Vocabulary: **Planarian Anatomy**
Term	Definition
PLANA:0000099	neuron
PLANA:0000101	muscle cell
PLANA:0000429	neoblast
PLANA:0002013	Category 1 cell
PLANA:0002109	X1 cell

Vocabulary: **INTERPRO**
Term	Definition
IPR004087	KH_dom
IPR004088	KH_dom_type_1

Vocabulary: **molecular function**
Term	Definition
GO:0003676	nucleic acid binding
GO:0003723	RNA binding

Main menu

KHD-1

Zeng et. al., 2018

▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Overview

Single cell RNA-seq of pluripotent neoblasts and its early progenies

Explore this single cell expression dataset with our NB Cluster Shiny App

Neoblast Population

Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Davies et. al., 2017

PAGE et. al., 2020

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE

PAGE Curations: 18

Owlery

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