Pleckstrin homology domain-containing family F member 2-like protein

Overview
NamePleckstrin homology domain-containing family F member 2-like protein
Smed IDSMED30013141
Length (bp)894
Neoblast Clusters

Zeng et. al., 2018



▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)



Explore this single cell expression dataset with our NB Cluster Shiny App



 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of Pleckstrin homology domain-containing family F member 2-like protein (SMED30013141) t-SNE clustered cells

Violin plots show distribution of expression levels for Pleckstrin homology domain-containing family F member 2-like protein (SMED30013141) in cells (dots) of each of the 12 neoblast clusters.

 

back to top

 

Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of Pleckstrin homology domain-containing family F member 2-like protein (SMED30013141) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for Pleckstrin homology domain-containing family F member 2-like protein (SMED30013141) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

back to top

 

Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
Sort Descending | Sort Ascending | Only Non-Zero Values | Tile/Chart | Reset

Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

back to top
Anatomical Expression

PAGE et. al., 2020



SMED30013141

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 6

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
pharynxSMED30013141 dd_Smed_v4_2374_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
protonephridiaSMED30013141 dd_Smed_v4_2374_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
epidermisSMED30013141 dd_Smed_v4_2374_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
cephalic gangliaSMED30013141 dd_Smed_v4_2374_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
parenchymal cellSMED30013141 dd_Smed_v4_2374_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
epidermisSMED30013141 dd_Smed_v4_2374_0_1dd_Smed_v4PMID:28292427
Wurtzel et al., 2017		whole organism asexual adult single-cell RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
[Close]
BLAST of Pleckstrin homology domain-containing family F member 2-like protein vs. Ensembl Human
Match: PLEKHF2 (pleckstrin homology and FYVE domain containing 2 [Source:HGNC Symbol;Acc:HGNC:20757])

HSP 1 Score: 193.741 bits (491), Expect = 3.287e-60
Identity = 95/212 (44.81%), Postives = 128/212 (60.38%), Query Frame = 1 
Query:  106 EANKERIKEIDSLFGNSYPPLYQEKRTLIGEGTLVKVCRKQSKKRQFFLFSDILVYCKYIWKGTKLTSQHVFPLSVMEIEEVPNNDILEHGFIIKSPKKSFIVYAATSDEREQWMRHIRNCMLQCGGESTYICVYNACSKADSLKSPVWVPDDETETCMVCRVTNFSLITRKHHCRKCGKVVCLKCSQKRFLIPEISCDTVRVCDTCYFVLS 741
            EAN  RI  +++ FG +  PL    R LIGEG L K+CRK+ K RQFFLF+DILVY   + +  K   QH+ PL  + I+ + +   L +G++IK+P KSF VYAAT+ E+ +WM HI  C+     +S             +  + VWVPD E   CM C+   F+ + R+HHCRKCG VVC  CS+KRFL+P  S   VR+CD CY +LS
Sbjct:    9 EANTRRISIVENCFGAAGQPLTIPGRVLIGEGVLTKLCRKKPKARQFFLFNDILVYGNIVIQKKKYNKQHIIPLENVTIDSIKDEGDLRNGWLIKTPTKSFAVYAATATEKSEWMNHINKCVTDLLSKSG--------KTPSNEHAAVWVPDSEATVCMRCQKAKFTPVNRRHHCRKCGFVVCGPCSEKRFLLPSQSSKPVRICDFCYDLLS 212
[Close]
BLAST of Pleckstrin homology domain-containing family F member 2-like protein vs. Ensembl Human
Match: PLEKHF2 (pleckstrin homology and FYVE domain containing 2 [Source:HGNC Symbol;Acc:HGNC:20757])

HSP 1 Score: 193.741 bits (491), Expect = 3.287e-60
Identity = 95/212 (44.81%), Postives = 128/212 (60.38%), Query Frame = 1 
Query:  106 EANKERIKEIDSLFGNSYPPLYQEKRTLIGEGTLVKVCRKQSKKRQFFLFSDILVYCKYIWKGTKLTSQHVFPLSVMEIEEVPNNDILEHGFIIKSPKKSFIVYAATSDEREQWMRHIRNCMLQCGGESTYICVYNACSKADSLKSPVWVPDDETETCMVCRVTNFSLITRKHHCRKCGKVVCLKCSQKRFLIPEISCDTVRVCDTCYFVLS 741
            EAN  RI  +++ FG +  PL    R LIGEG L K+CRK+ K RQFFLF+DILVY   + +  K   QH+ PL  + I+ + +   L +G++IK+P KSF VYAAT+ E+ +WM HI  C+     +S             +  + VWVPD E   CM C+   F+ + R+HHCRKCG VVC  CS+KRFL+P  S   VR+CD CY +LS
Sbjct:    9 EANTRRISIVENCFGAAGQPLTIPGRVLIGEGVLTKLCRKKPKARQFFLFNDILVYGNIVIQKKKYNKQHIIPLENVTIDSIKDEGDLRNGWLIKTPTKSFAVYAATATEKSEWMNHINKCVTDLLSKSG--------KTPSNEHAAVWVPDSEATVCMRCQKAKFTPVNRRHHCRKCGFVVCGPCSEKRFLLPSQSSKPVRICDFCYDLLS 212
[Close]
BLAST of Pleckstrin homology domain-containing family F member 2-like protein vs. Ensembl Human
Match: PLEKHF1 (pleckstrin homology and FYVE domain containing 1 [Source:HGNC Symbol;Acc:HGNC:20764])

HSP 1 Score: 181.03 bits (458), Expect = 5.622e-55
Identity = 91/209 (43.54%), Postives = 128/209 (61.24%), Query Frame = 1 
Query:  106 EANKERIKEIDSLFGNSYPPLYQEKRTLIGEGTLVKVCRKQSKKRQFFLFSDILVYCKYIWKGTKLTSQHVFPLSVMEIEEVPNNDILEHGFIIKSPKKSFIVYAATSDEREQWMRHIRNCMLQCGGESTYICVYNACSKADSLK-SPVWVPDDETETCMVCRVTNFSLITRKHHCRKCGKVVCLKCSQKRFLIPEISCDTVRVCDTCY 729
            E N +RI  ++S FG S  PL    R L+GEG L K CRK++K R FFLF+DILVY   +    K  SQH+ PL  + +E +P     ++ ++IK+ KKSF+V AA++ ER++W+ HI  C+ +            A  +  S + +  W+PD  T+ CM C  T FS +TR+HHCRKCG VVC +CS++RFL+P +S   VRVC  CY
Sbjct:    9 EINSQRIAAVESCFGASGQPLALPGRVLLGEGVLTKECRKKAKPRIFFLFNDILVYGSIVLNKRKYRSQHIIPLEEVTLELLPETLQAKNRWMIKTAKKSFVVSAASATERQEWISHIEECVRR---------QLRATGRPPSTEHAAPWIPDKATDICMRCTQTRFSALTRRHHCRKCGFVVCAECSRQRFLLPRLSPKPVRVCSLCY 208
[Close]
BLAST of Pleckstrin homology domain-containing family F member 2-like protein vs. Ensembl Human
Match: PLEKHF1 (pleckstrin homology and FYVE domain containing 1 [Source:HGNC Symbol;Acc:HGNC:20764])

HSP 1 Score: 181.03 bits (458), Expect = 5.622e-55
Identity = 91/209 (43.54%), Postives = 128/209 (61.24%), Query Frame = 1 
Query:  106 EANKERIKEIDSLFGNSYPPLYQEKRTLIGEGTLVKVCRKQSKKRQFFLFSDILVYCKYIWKGTKLTSQHVFPLSVMEIEEVPNNDILEHGFIIKSPKKSFIVYAATSDEREQWMRHIRNCMLQCGGESTYICVYNACSKADSLK-SPVWVPDDETETCMVCRVTNFSLITRKHHCRKCGKVVCLKCSQKRFLIPEISCDTVRVCDTCY 729
            E N +RI  ++S FG S  PL    R L+GEG L K CRK++K R FFLF+DILVY   +    K  SQH+ PL  + +E +P     ++ ++IK+ KKSF+V AA++ ER++W+ HI  C+ +            A  +  S + +  W+PD  T+ CM C  T FS +TR+HHCRKCG VVC +CS++RFL+P +S   VRVC  CY
Sbjct:    9 EINSQRIAAVESCFGASGQPLALPGRVLLGEGVLTKECRKKAKPRIFFLFNDILVYGSIVLNKRKYRSQHIIPLEEVTLELLPETLQAKNRWMIKTAKKSFVVSAASATERQEWISHIEECVRR---------QLRATGRPPSTEHAAPWIPDKATDICMRCTQTRFSALTRRHHCRKCGFVVCAECSRQRFLLPRLSPKPVRVCSLCY 208
[Close]
BLAST of Pleckstrin homology domain-containing family F member 2-like protein vs. Ensembl Human
Match: FGD6 (FYVE, RhoGEF and PH domain containing 6 [Source:HGNC Symbol;Acc:HGNC:21740])

HSP 1 Score: 120.168 bits (300), Expect = 1.487e-31
Identity = 64/210 (30.48%), Postives = 113/210 (53.81%), Query Frame = 1 
Query:  151 NSYPPLYQEKRTLIGEGTLVKVCRKQSKKRQFFLFSDILVYCKYIWKGT-KLTSQHVFPLSVMEIEEVPNNDILEHGFIIKSPKKSFIVYAATSDEREQWMRHIRNCMLQCGGESTYICVYNACSKADS----------LKSPVWVPDDETETCMVCRVTNFSLITRKHHCRKCGKVVCLKCSQKRFLIPEISCDTVRVCDTCYFVLSQI 747
            N +  + Q  R  + EG L+K+ RK  + R FFLF+D L+Y   +  G  KL   ++  L+ M++ + P  +  ++   I+S ++SFI+ A+++ ER++W+  I   + +   +    C   +  +ADS           K+P+W+PD     CM+C  + F+L  R+HHCR CGK+VC  CS  ++ +  +     RVC+ C+  L ++
Sbjct:   74 NGHHEIVQPGRVFLKEGILMKLSRKVMQPRMFFLFNDALLYTTPVQSGMYKLN--NMLSLAGMKVRK-PTQEAYQNELKIESVERSFILSASSATERDEWLEAISRAIEEYAKKRITFCPSRSLDEADSENKEEVSPLGSKAPIWIPDTRATMCMIC-TSEFTLTWRRHHCRACGKIVCQACSSNKYGLDYLKNQPARVCEHCFQELQKL 279
[Close]
BLAST of Pleckstrin homology domain-containing family F member 2-like protein vs. Ensembl Celegans
Match: ZK632.12 (pep chromosome:WBcel235:III:9830802:9832378:1 gene:WBGene00014019.1 transcript:ZK632.12.2 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:ZK632.12)

HSP 1 Score: 181.8 bits (460), Expect = 7.179e-56
Identity = 89/212 (41.98%), Postives = 124/212 (58.49%), Query Frame = 1 
Query:  106 EANKERIKEIDSLFGNSYPPLYQEKRTLIGEGTLVKVCRKQSKKRQFFLFSDILVYCKYIWKGTKLTSQHVFPLSVMEIEEVPNNDILEHGFIIKSPKKSFIVYAATSDEREQWMRHIRNCMLQCGGESTYICVYNACSKADSLKSPVWVPDDETETCMVCRVTNFSLITRKHHCRKCGKVVCLKCSQKRFLIPEISCDTVRVCDTCYFVLS 741
            E N  R+  ++  FG     L    R L+GEG LVK+CRK+ K+RQFFLF+DILVY   +    +   Q +  L  +++E++ ++ I +HG+IIK+P KSF VYAAT  E+ +WM HI  C+           +     +A +  + VWVPD E   CMVC  T F+L+ R+HHCR CG+VVC  CS + F I  +    VRVCD C+  LS
Sbjct:    9 EVNSRRMANVEQCFGKMGEQLSVFGRVLVGEGVLVKMCRKKPKQRQFFLFNDILVYGNIVISKKRYNKQRILRLEGVQVEDLEDDGIEKHGWIIKTPAKSFAVYAATETEKREWMLHIERCVTD--------LLERGNKQAATAHAAVWVPDGEAVKCMVCGKTQFNLVQRRHHCRNCGRVVCGACSSRTFRIDNVHKKPVRVCDHCFDSLS 212
[Close]
BLAST of Pleckstrin homology domain-containing family F member 2-like protein vs. Ensembl Celegans
Match: ZK632.12 (pep chromosome:WBcel235:III:9830792:9832430:1 gene:WBGene00014019.1 transcript:ZK632.12.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:ZK632.12)

HSP 1 Score: 181.8 bits (460), Expect = 7.179e-56
Identity = 89/212 (41.98%), Postives = 124/212 (58.49%), Query Frame = 1 
Query:  106 EANKERIKEIDSLFGNSYPPLYQEKRTLIGEGTLVKVCRKQSKKRQFFLFSDILVYCKYIWKGTKLTSQHVFPLSVMEIEEVPNNDILEHGFIIKSPKKSFIVYAATSDEREQWMRHIRNCMLQCGGESTYICVYNACSKADSLKSPVWVPDDETETCMVCRVTNFSLITRKHHCRKCGKVVCLKCSQKRFLIPEISCDTVRVCDTCYFVLS 741
            E N  R+  ++  FG     L    R L+GEG LVK+CRK+ K+RQFFLF+DILVY   +    +   Q +  L  +++E++ ++ I +HG+IIK+P KSF VYAAT  E+ +WM HI  C+           +     +A +  + VWVPD E   CMVC  T F+L+ R+HHCR CG+VVC  CS + F I  +    VRVCD C+  LS
Sbjct:    9 EVNSRRMANVEQCFGKMGEQLSVFGRVLVGEGVLVKMCRKKPKQRQFFLFNDILVYGNIVISKKRYNKQRILRLEGVQVEDLEDDGIEKHGWIIKTPAKSFAVYAATETEKREWMLHIERCVTD--------LLERGNKQAATAHAAVWVPDGEAVKCMVCGKTQFNLVQRRHHCRNCGRVVCGACSSRTFRIDNVHKKPVRVCDHCFDSLS 212
[Close]
BLAST of Pleckstrin homology domain-containing family F member 2-like protein vs. Ensembl Celegans
Match: aka-1 (A Kinase Anchor protein [Source:UniProtKB/TrEMBL;Acc:H2KZI9])

HSP 1 Score: 71.633 bits (174), Expect = 1.186e-13
Identity = 30/75 (40.00%), Postives = 45/75 (60.00%), Query Frame = 1 
Query:  541 SPVWVPDDETETCMVCRVTNFSLITRKHHCRKCGKVVCLKCSQKRFLIPEIS-----CDTVRVCDTCYFVLSQIQ 750
            SP W+PD E   CM+C  T F++ITR+HHCR CG+V+C  C  ++  +  +         VRVC  C  +L++I+
Sbjct:  535 SPYWIPDSECPNCMLCN-TRFTIITRRHHCRACGRVLCGSCCNEKAFLEYLQEEGKKLQAVRVCKPCSAMLARIE 608
[Close]
BLAST of Pleckstrin homology domain-containing family F member 2-like protein vs. Ensembl Celegans
Match: aka-1 (A Kinase Anchor protein [Source:UniProtKB/TrEMBL;Acc:H2KZI9])

HSP 1 Score: 71.633 bits (174), Expect = 1.186e-13
Identity = 30/75 (40.00%), Postives = 45/75 (60.00%), Query Frame = 1 
Query:  541 SPVWVPDDETETCMVCRVTNFSLITRKHHCRKCGKVVCLKCSQKRFLIPEIS-----CDTVRVCDTCYFVLSQIQ 750
            SP W+PD E   CM+C  T F++ITR+HHCR CG+V+C  C  ++  +  +         VRVC  C  +L++I+
Sbjct:  535 SPYWIPDSECPNCMLCN-TRFTIITRRHHCRACGRVLCGSCCNEKAFLEYLQEEGKKLQAVRVCKPCSAMLARIE 608
[Close]
BLAST of Pleckstrin homology domain-containing family F member 2-like protein vs. Ensembl Celegans
Match: aka-1 (A Kinase Anchor protein [Source:UniProtKB/TrEMBL;Acc:H2KZI9])

HSP 1 Score: 65.0846 bits (157), Expect = 1.682e-11
Identity = 28/75 (37.33%), Postives = 43/75 (57.33%), Query Frame = 1 
Query:  541 SPVWVPDDETETCMVCRVTNFSLITRKHHCRKCGKVVCLKCSQKRFLIPEIS-----CDTVRVCDTCYFVLSQIQ 750
            SP W+PD E   CM+     F++ITR+HHCR CG+V+C  C  ++  +  +         VRVC  C  +L++I+
Sbjct:  535 SPYWIPDSECPNCML-----FTIITRRHHCRACGRVLCGSCCNEKAFLEYLQEEGKKLQAVRVCKPCSAMLARIE 604
[Close]
BLAST of Pleckstrin homology domain-containing family F member 2-like protein vs. Ensembl Fly
Match: rush (gene:FBgn0025381 transcript:FBtr0070259)

HSP 1 Score: 197.593 bits (501), Expect = 3.039e-61
Identity = 93/214 (43.46%), Postives = 129/214 (60.28%), Query Frame = 1 
Query:  106 EANKERIKEIDSLFGNSYPPLYQEKRTLIGEGTLVKVCRKQSKKRQFFLFSDILVYCKYIWKGTKLTSQHVFPLSVMEIEEVPNNDILEHGFIIKSPKKSFIVYAATSDEREQWMRHIRNCMLQCGGESTYICVYNACSKADSLKSPVWVPDDETETCMVCRVTNFSLITRKHHCRKCGKVVCLKCSQKRFLIPEISCDTVRVCDTCYFVLSQI 747
            EAN  RI  +++ FG+S  PL  + R L+GEG L K+CRK+ K RQFFLF+DILVY   +    K   QH+ PL  + +E + +N    +G+ I++  KSF+V+AATS E+++WM HI  C+     +S    V N         + VWVPD +   CM C+ T F+ I R+HHCR CG VVC  CS K+FL+P+ S   +RVCD CY  L  +
Sbjct:    9 EANTRRIASVENCFGSSGVPLAMQGRVLVGEGVLTKMCRKRPKSRQFFLFNDILVYGNIVIGKKKYNKQHIMPLEEVSLESIADNQTYRNGWYIRTTTKSFVVFAATSTEKQEWMAHINKCVEDLLRKSGKKPVEN--------HAAVWVPDTDASVCMHCKKTQFTFIQRRHHCRNCGAVVCAGCSAKKFLLPQQSTKALRVCDACYERLKHV 214
[Close]
BLAST of Pleckstrin homology domain-containing family F member 2-like protein vs. Ensembl Fly
Match: rush (gene:FBgn0025381 transcript:FBtr0339589)

HSP 1 Score: 197.593 bits (501), Expect = 3.039e-61
Identity = 93/214 (43.46%), Postives = 129/214 (60.28%), Query Frame = 1 
Query:  106 EANKERIKEIDSLFGNSYPPLYQEKRTLIGEGTLVKVCRKQSKKRQFFLFSDILVYCKYIWKGTKLTSQHVFPLSVMEIEEVPNNDILEHGFIIKSPKKSFIVYAATSDEREQWMRHIRNCMLQCGGESTYICVYNACSKADSLKSPVWVPDDETETCMVCRVTNFSLITRKHHCRKCGKVVCLKCSQKRFLIPEISCDTVRVCDTCYFVLSQI 747
            EAN  RI  +++ FG+S  PL  + R L+GEG L K+CRK+ K RQFFLF+DILVY   +    K   QH+ PL  + +E + +N    +G+ I++  KSF+V+AATS E+++WM HI  C+     +S    V N         + VWVPD +   CM C+ T F+ I R+HHCR CG VVC  CS K+FL+P+ S   +RVCD CY  L  +
Sbjct:    9 EANTRRIASVENCFGSSGVPLAMQGRVLVGEGVLTKMCRKRPKSRQFFLFNDILVYGNIVIGKKKYNKQHIMPLEEVSLESIADNQTYRNGWYIRTTTKSFVVFAATSTEKQEWMAHINKCVEDLLRKSGKKPVEN--------HAAVWVPDTDASVCMHCKKTQFTFIQRRHHCRNCGAVVCAGCSAKKFLLPQQSTKALRVCDACYERLKHV 214
[Close]
BLAST of Pleckstrin homology domain-containing family F member 2-like protein vs. Ensembl Fly
Match: Sara (gene:FBgn0026369 transcript:FBtr0071641)

HSP 1 Score: 76.2554 bits (186), Expect = 5.048e-15
Identity = 31/69 (44.93%), Postives = 43/69 (62.32%), Query Frame = 1 
Query:  544 PVWVPDDETETCMVCRVTNFSLITRKHHCRKCGKVVCLKCSQKRFLIPEISCDTVRVCDTCYFVLSQIQ 750
            P+WVPD+    CM C+   F++I R+HHCR CGKV+C  C  +RF +   +    RVC  CY +LS+ Q
Sbjct:  526 PIWVPDNMAGQCMQCQ-QKFTMIKRRHHCRACGKVLCSVCCSQRFRLEFATEPESRVCVQCYMILSERQ 593
[Close]
BLAST of Pleckstrin homology domain-containing family F member 2-like protein vs. Ensembl Fly
Match: CG6051 (gene:FBgn0039492 transcript:FBtr0339264)

HSP 1 Score: 68.1662 bits (165), Expect = 2.341e-12
Identity = 30/74 (40.54%), Postives = 40/74 (54.05%), Query Frame = 1 
Query:  511 NACSKADSLKSPVWVPDDETETCMVCRVTNFSLITRKHHCRKCGKVVCLKCSQKRFLIPEIS-CDTVRVCDTCY 729
            +A S + +L  P W+PD +   CM C+ T F+   R+HHCR CG V C  CS     +P+      VRVC  CY
Sbjct:  892 SATSTSATLSPPAWIPDGKAPRCMACQ-TPFTAFRRRHHCRNCGGVFCGVCSNASAPLPKYGLTKAVRVCRDCY 964
[Close]
BLAST of Pleckstrin homology domain-containing family F member 2-like protein vs. Ensembl Fly
Match: CG6051 (gene:FBgn0039492 transcript:FBtr0305050)

HSP 1 Score: 68.1662 bits (165), Expect = 2.341e-12
Identity = 30/74 (40.54%), Postives = 40/74 (54.05%), Query Frame = 1 
Query:  511 NACSKADSLKSPVWVPDDETETCMVCRVTNFSLITRKHHCRKCGKVVCLKCSQKRFLIPEIS-CDTVRVCDTCY 729
            +A S + +L  P W+PD +   CM C+ T F+   R+HHCR CG V C  CS     +P+      VRVC  CY
Sbjct:  893 SATSTSATLSPPAWIPDGKAPRCMACQ-TPFTAFRRRHHCRNCGGVFCGVCSNASAPLPKYGLTKAVRVCRDCY 965
[Close]
BLAST of Pleckstrin homology domain-containing family F member 2-like protein vs. Ensembl Zebrafish
Match: plekhf2 (pleckstrin homology domain containing, family F (with FYVE domain) member 2 [Source:NCBI gene;Acc:393214])

HSP 1 Score: 191.045 bits (484), Expect = 1.866e-59
Identity = 97/215 (45.12%), Postives = 130/215 (60.47%), Query Frame = 1 
Query:  106 EANKERIKEIDSLFGNSYPPLYQEKRTLIGEGTLVKVCRKQSKKRQFFLFSDILVYCKYIWKGTKLTSQHVFPLSVMEIEEVPNNDILEHGFIIKSPKKSFIVYAATSDEREQWMRHIRNC---MLQCGGESTYICVYNACSKADSLKSPVWVPDDETETCMVCRVTNFSLITRKHHCRKCGKVVCLKCSQKRFLIPEISCDTVRVCDTCYFVLS 741
            EAN +RI  +++ FG +  PL    R LIGEG L K+CRK+ K RQFFLF+DILVY   + +  K   QH+ PL  + I+ V +   L +G++IK+P KSF VYAAT+ E+ +WM HI  C   +L+  G+S                + VWVPD E   CM C+   F+ + R+HHCRKCG VVC  CS+K+FL+P  S   VRVC+ CY  LS
Sbjct:    9 EANSKRIGVVEACFGTAGQPLAIPGRVLIGEGVLTKLCRKRPKARQFFLFNDILVYGNIVIQKKKYNKQHIIPLESVTIDTVEDEGELRNGWLIKTPTKSFAVYAATATEKSEWMSHINKCVSDLLEKSGKS-----------PTGEHAAVWVPDSEATVCMRCQKMKFTPVNRRHHCRKCGFVVCGPCSEKKFLLPSQSSKPVRVCEFCYKQLS 212
[Close]
BLAST of Pleckstrin homology domain-containing family F member 2-like protein vs. Ensembl Zebrafish
Match: plekhf2 (pleckstrin homology domain containing, family F (with FYVE domain) member 2 [Source:NCBI gene;Acc:393214])

HSP 1 Score: 191.045 bits (484), Expect = 1.866e-59
Identity = 97/215 (45.12%), Postives = 130/215 (60.47%), Query Frame = 1 
Query:  106 EANKERIKEIDSLFGNSYPPLYQEKRTLIGEGTLVKVCRKQSKKRQFFLFSDILVYCKYIWKGTKLTSQHVFPLSVMEIEEVPNNDILEHGFIIKSPKKSFIVYAATSDEREQWMRHIRNC---MLQCGGESTYICVYNACSKADSLKSPVWVPDDETETCMVCRVTNFSLITRKHHCRKCGKVVCLKCSQKRFLIPEISCDTVRVCDTCYFVLS 741
            EAN +RI  +++ FG +  PL    R LIGEG L K+CRK+ K RQFFLF+DILVY   + +  K   QH+ PL  + I+ V +   L +G++IK+P KSF VYAAT+ E+ +WM HI  C   +L+  G+S                + VWVPD E   CM C+   F+ + R+HHCRKCG VVC  CS+K+FL+P  S   VRVC+ CY  LS
Sbjct:    9 EANSKRIGVVEACFGTAGQPLAIPGRVLIGEGVLTKLCRKRPKARQFFLFNDILVYGNIVIQKKKYNKQHIIPLESVTIDTVEDEGELRNGWLIKTPTKSFAVYAATATEKSEWMSHINKCVSDLLEKSGKS-----------PTGEHAAVWVPDSEATVCMRCQKMKFTPVNRRHHCRKCGFVVCGPCSEKKFLLPSQSSKPVRVCEFCYKQLS 212
[Close]
BLAST of Pleckstrin homology domain-containing family F member 2-like protein vs. Ensembl Zebrafish
Match: plekhf1 (pleckstrin homology domain containing, family F (with FYVE domain) member 1 [Source:ZFIN;Acc:ZDB-GENE-040426-1289])

HSP 1 Score: 141.354 bits (355), Expect = 1.039e-39
Identity = 75/208 (36.06%), Postives = 118/208 (56.73%), Query Frame = 1 
Query:  112 NKERIKEIDSLFGNSYPPLYQEKRTLIGEGTLVKVCRKQSKKRQFFLFSDILVYCKYIWKGTKLTSQHVFPLSVMEIEEVPNNDILEHGFIIKSPKKSFIVYAATSDEREQWMRHI---RNCMLQCGGESTYICVYNACSKADSLKSPVWVPDDETETCMVCRVTNFSLITRKHHCRKCGKVVCLKCSQKRFLIPEISCDTVRVCDTC 726
            N+ERI+ ++S FG +   L +  R L+GEG L K+CR+  + R F+LF+DILVY   +  G     Q++ PL  ++ E++ +   + + ++I++P+KSF V A + +E+  WM HI   R   ++  G         A    D   +P W+PD  +  CM C    F++  R+HHCR+CG +VC  CS+ R ++P IS   VRVC  C
Sbjct:   11 NRERIQAVESSFGRTGKMLQKPGRFLVGEGCLQKLCRRGPQPRVFYLFNDILVYGSIMLHGRWNNKQNIIPLEEVQQEDLEDGMAMANQWLIRTPRKSFYVSAESPEEKIAWMGHIEQYRTLHVKNKG-------LPAKKSGDDFATP-WIPDVASAICMRC-SKRFTVANRRHHCRRCGYIVCQACSKGRAVLPHISNRPVRVCRNC 209
[Close]
BLAST of Pleckstrin homology domain-containing family F member 2-like protein vs. Ensembl Zebrafish
Match: plekhf1 (pleckstrin homology domain containing, family F (with FYVE domain) member 1 [Source:ZFIN;Acc:ZDB-GENE-040426-1289])

HSP 1 Score: 141.354 bits (355), Expect = 1.039e-39
Identity = 75/208 (36.06%), Postives = 118/208 (56.73%), Query Frame = 1 
Query:  112 NKERIKEIDSLFGNSYPPLYQEKRTLIGEGTLVKVCRKQSKKRQFFLFSDILVYCKYIWKGTKLTSQHVFPLSVMEIEEVPNNDILEHGFIIKSPKKSFIVYAATSDEREQWMRHI---RNCMLQCGGESTYICVYNACSKADSLKSPVWVPDDETETCMVCRVTNFSLITRKHHCRKCGKVVCLKCSQKRFLIPEISCDTVRVCDTC 726
            N+ERI+ ++S FG +   L +  R L+GEG L K+CR+  + R F+LF+DILVY   +  G     Q++ PL  ++ E++ +   + + ++I++P+KSF V A + +E+  WM HI   R   ++  G         A    D   +P W+PD  +  CM C    F++  R+HHCR+CG +VC  CS+ R ++P IS   VRVC  C
Sbjct:   11 NRERIQAVESSFGRTGKMLQKPGRFLVGEGCLQKLCRRGPQPRVFYLFNDILVYGSIMLHGRWNNKQNIIPLEEVQQEDLEDGMAMANQWLIRTPRKSFYVSAESPEEKIAWMGHIEQYRTLHVKNKG-------LPAKKSGDDFATP-WIPDVASAICMRC-SKRFTVANRRHHCRRCGYIVCQACSKGRAVLPHISNRPVRVCRNC 209
[Close]
BLAST of Pleckstrin homology domain-containing family F member 2-like protein vs. Ensembl Zebrafish
Match: fgd6 (FYVE, RhoGEF and PH domain containing 6 [Source:ZFIN;Acc:ZDB-GENE-041210-200])

HSP 1 Score: 118.627 bits (296), Expect = 2.608e-29
Identity = 71/207 (34.30%), Postives = 114/207 (55.07%), Query Frame = 1 
Query:  151 NSYPPLYQEKRTLIGEGTLVKVCRKQSKKRQFFLFSDILVYCKYIWKGT-KLTSQHVFPLSVMEIEEVPNNDILEHGFIIKSPKKSFIVYAATSDEREQWMRHIRNCMLQCGGESTYICVYNACSKA------DSL----KSPVWVPDDETETCMVCRVTNFSLITRKHHCRKCGKVVCLKCSQKRFLIPEISCDTVRVCDTCYFVL 738
            N +  + Q  R  + EGTL+K+ RK  + R FFLF+DIL+Y   +  G  K+ S  +  L+ M++ + P+ +  ++   I+S ++SFI+ A ++ ER++W+  I   +     +   I  +++ S+       D L    K+P+W+PD  T  CM+C    F+L  R+HHCR CGKVVC  CS  +F +  +     RVCD CY  L
Sbjct:  951 NGHHEIVQPGRVFLKEGTLMKLSRKVMQPRMFFLFNDILLYTTPVQSGQYKVNS--MLSLAGMKVSK-PSQEAYQNELNIESVERSFILSANSATERDEWLEAIATAIDDYTRKK--ISFFSSRSQELEGISDDGLPLGSKAPIWIPDLRTTMCMIC-TCEFTLTWRRHHCRACGKVVCQACSSNKFYLEYLKNQLARVCDHCYIKL 1151
[Close]
BLAST of Pleckstrin homology domain-containing family F member 2-like protein vs. Ensembl Xenopus
Match: eif4g3 (eukaryotic translation initiation factor 4 gamma, 3 [Source:Xenbase;Acc:XB-GENE-1010293])

HSP 1 Score: 195.282 bits (495), Expect = 6.360e-61
Identity = 94/213 (44.13%), Postives = 130/213 (61.03%), Query Frame = 1 
Query:  106 EANKERIKEIDSLFGNSYPPLYQEKRTLIGEGTLVKVCRKQSKKRQFFLFSDILVYCKYIWKGTKLTSQHVFPLSVMEIEEVPNNDILEHGFIIKSPKKSFIVYAATSDEREQWMRHIRNCMLQCGGESTYICVYNACSKADSLKSPVWVPDDETETCMVCRVTNFSLITRKHHCRKCGKVVCLKCSQKRFLIPEISCDTVRVCDTCYFVLSQ 744
            EAN +RI  ++S FG +  PL    R LIGEG L K+CRK+ K RQFFLF+DILVY   + +  K   QH+ PL  + I+ + +   L +G++IK+P KSF VYAAT+ E+ +WM HI  C+           +  +    +S  + VW+PD E   CM C+   F+ + R+HHCRKCG V+C  CS+KR+L+P  S   VRVCD CY +LS 
Sbjct:    9 EANSKRINLVESCFGTAGQPLAIPGRVLIGEGVLTKLCRKKPKARQFFLFNDILVYGNIVIQKKKYNKQHIIPLENVTIDTIEDEGELRNGWLIKTPTKSFAVYAATATEKSEWMNHINKCVCD--------LISKSGKTPNSEHAAVWIPDSEATICMRCKKVKFTPVNRRHHCRKCGYVICGPCSEKRYLLPSQSSKPVRVCDFCYDLLSN 213
[Close]
BLAST of Pleckstrin homology domain-containing family F member 2-like protein vs. Ensembl Xenopus
Match: plekhf1 (pleckstrin homology and FYVE domain containing 1 [Source:NCBI gene;Acc:548764])

HSP 1 Score: 173.711 bits (439), Expect = 2.604e-52
Identity = 87/208 (41.83%), Postives = 124/208 (59.62%), Query Frame = 1 
Query:  106 EANKERIKEIDSLFGNSYPPLYQEKRTLIGEGTLVKVCRKQSKKRQFFLFSDILVYCKYIWKGTKLTSQHVFPLSVMEIEEVPNNDILEHGFIIKSPKKSFIVYAATSDEREQWMRHIRNCMLQCGGESTYICVYNACSKADSLKSPVWVPDDETETCMVCRVTNFSLITRKHHCRKCGKVVCLKCSQKRFLIPEISCDTVRVCDTCY 729
            E N +RI  +++ FG S  PL    R L+GEG L K CRK+ K R FFLFSDILVY   +    +  +Q + PL  + +E +P++  + + ++IK+ KKSF+V AA+  ER++W+ HI  C+ Q         +     +     +  W+PD  T+ CM C  TNF+L+ R+HHCRKCG VVC +CS+ +FLIP I    VRVC  CY
Sbjct:    9 EINAQRIAVVENCFGTSGQPLSTPGRVLVGEGILTKECRKKPKPRTFFLFSDILVYGNIVINKVRYNTQRIIPLEDVTVEILPDSIDMRNRWMIKTSKKSFVVSAASYSERKEWICHIEECIHQ--------LLQKTGRQPSKEHAAPWIPDKATDICMRCTQTNFTLVNRRHHCRKCGFVVCHECSKYKFLIPTIKSKPVRVCSLCY 208
[Close]
BLAST of Pleckstrin homology domain-containing family F member 2-like protein vs. Ensembl Xenopus
Match: mc3r (melanocortin 3 receptor [Source:Xenbase;Acc:XB-GENE-986713])

HSP 1 Score: 113.62 bits (283), Expect = 1.752e-27
Identity = 62/209 (29.67%), Postives = 110/209 (52.63%), Query Frame = 1 
Query:  151 NSYPPLYQEKRTLIGEGTLVKVCRKQSKKRQFFLFSDILVYCKYIWKGT-KLTSQHVFPLSVMEIEEVPNNDILEHGFIIKSPKKSFIVYAATSDEREQWMRHIRNCMLQCGGESTYICVYNACSKADSLK---------SPVWVPDDETETCMVCRVTNFSLITRKHHCRKCGKVVCLKCSQKRFLIPEISCDTVRVCDTCYFVLSQI 747
            N +  + Q  R  + EGTL+K+ RK  + R F+LF+D L+Y   +  G  KL   ++  L+ M++ + P  +  ++   I+S ++SFI+ A+++ ER+ W+  I   + +   +        +  +AD  +         +P+W+PD     CM+C  + F+L  R+HHCR CGK++C  CS  +  +  +     RVCD C+ VL  +
Sbjct:  995 NGHHEIVQPGRVFLKEGTLMKLSRKVMQPRMFYLFNDALLYTTPVQSGMYKLN--NMLSLAGMKVRK-PTQEAYQNELNIESVERSFILSASSASERDDWLEAISLAIEEYAKKKITFNPTKSLEEADPGEKEDCTLGSTAPIWIPDGRVTMCMIC-TSEFTLTWRRHHCRACGKIICQACSTNKHSLEYLKNHLARVCDRCFQVLQNL 1199
[Close]
BLAST of Pleckstrin homology domain-containing family F member 2-like protein vs. Ensembl Xenopus
Match: FGD4 (FYVE, RhoGEF and PH domain containing 4 [Source:NCBI gene;Acc:100038050])

HSP 1 Score: 90.8929 bits (224), Expect = 7.887e-20
Identity = 57/188 (30.32%), Postives = 96/188 (51.06%), Query Frame = 1 
Query:  187 LIGEGTLVKVCRKQ--SKKRQFFLFSDILVYC--KYIWKGTKLTSQHVFPLSVMEIEEVPNNDILEHGFIIKSPKKSFIVYAATSDEREQWMRHIRNCMLQCGGESTYICVYNACSKADSLKSPVWVPDDETETCMVCRVTNFSLITRKHHCRKCGKVVCLKCSQKRFLIPEISCDTVRVCDTCYFVL 738
            LI EG ++K+  +   +++R  FL +++L+YC  K+   GTK T +    L  M++ E  N D   H F I   +++  + A++   +E+W++   N  +          +Y +      L++P W+ D+E   CM C+    +L  R+HHCR CG VVC KCS  +  +   S    +VC  CY +L
Sbjct:  245 LIKEGQILKLAARNTSAQERYLFLLNNMLLYCVPKFSLVGTKYTLRTKIGLEGMKVVETQNED-YPHTFQISGKERTLELQASSEQNKEEWIKVSDNYYIIL---IYLYILYLSSISELGLRAPRWIRDNEVTMCMKCKEQFNALTRRRHHCRACGYVVCWKCSDYKATLEYDSNKMNKVCKDCYKIL 428
[Close]
BLAST of Pleckstrin homology domain-containing family F member 2-like protein vs. Ensembl Xenopus
Match: FGD4 (FYVE, RhoGEF and PH domain containing 4 [Source:NCBI gene;Acc:100038050])

HSP 1 Score: 83.9593 bits (206), Expect = 1.590e-17
Identity = 59/196 (30.10%), Postives = 95/196 (48.47%), Query Frame = 1 
Query:  187 LIGEGTLVKVCRKQ--SKKRQFFLFSDILVYC--KYIWKGTKLTSQHVFPLSVMEIEEVPNNDILEHGFIIKSPKKSFIVYAATSDEREQWMRHIRNCM--LQCGGESTYICVYNACSKADS------LKSPVWVPDDETETCMVCRVTNFSLITRKHHCRKCGKVVCLKCSQKRFLIPEISCDTVRVCDTCYFVL 738
            LI EG ++K+  +   +++R  FL +++L+YC  K+   GTK T +    L  M++ E  N D   H F I            +  ER   ++ +R+ +  +Q   E+  I +     +  S      L++P W+ D+E   CM C+    +L  R+HHCR CG VVC KCS  +  +   S    +VC  CY +L
Sbjct:  205 LIKEGQILKLAARNTSAQERYLFLLNNMLLYCVPKFSLVGTKYTLRTKIGLEGMKVVETQNEDY-PHTFQI------------SGKERTLELQALRDTIAEVQQKNETFKIAIAKELEETPSEVAELGLRAPRWIRDNEVTMCMKCKEQFNALTRRRHHCRACGYVVCWKCSDYKATLEYDSNKMNKVCKDCYKIL 387
[Close]
BLAST of Pleckstrin homology domain-containing family F member 2-like protein vs. Ensembl Mouse
Match: Plekhf2 (pleckstrin homology domain containing, family F (with FYVE domain) member 2 [Source:MGI Symbol;Acc:MGI:1919051])

HSP 1 Score: 194.512 bits (493), Expect = 1.082e-60
Identity = 96/212 (45.28%), Postives = 128/212 (60.38%), Query Frame = 1 
Query:  106 EANKERIKEIDSLFGNSYPPLYQEKRTLIGEGTLVKVCRKQSKKRQFFLFSDILVYCKYIWKGTKLTSQHVFPLSVMEIEEVPNNDILEHGFIIKSPKKSFIVYAATSDEREQWMRHIRNCMLQCGGESTYICVYNACSKADSLKSPVWVPDDETETCMVCRVTNFSLITRKHHCRKCGKVVCLKCSQKRFLIPEISCDTVRVCDTCYFVLS 741
            EAN  RI  ++S FG +  PL    R LIGEG L K+CRK+ K RQFFLF+DILVY   + +  K   QH+ PL  + I+ + +   L +G++IK+P KSF VYAAT+ E+ +WM HI  C+     +S             +  + VWVPD E   CM C+   F+ + R+HHCRKCG VVC  CS+KRFL+P  S   VR+CD CY +LS
Sbjct:    9 EANTRRISIVESCFGAAGQPLTIPGRVLIGEGVLTKLCRKKPKARQFFLFNDILVYGNIVIQKKKYNKQHIIPLENVTIDSIKDEGELRNGWLIKTPTKSFAVYAATATEKSEWMNHINKCVTDLLSKSG--------KTPSNEHAAVWVPDSEATVCMRCQKAKFTPVNRRHHCRKCGFVVCGPCSEKRFLLPSQSSKPVRICDFCYDLLS 212
[Close]
BLAST of Pleckstrin homology domain-containing family F member 2-like protein vs. Ensembl Mouse
Match: Plekhf2 (pleckstrin homology domain containing, family F (with FYVE domain) member 2 [Source:MGI Symbol;Acc:MGI:1919051])

HSP 1 Score: 178.333 bits (451), Expect = 3.841e-55
Identity = 88/197 (44.67%), Postives = 118/197 (59.90%), Query Frame = 1 
Query:  106 EANKERIKEIDSLFGNSYPPLYQEKRTLIGEGTLVKVCRKQSKKRQFFLFSDILVYCKYIWKGTKLTSQHVFPLSVMEIEEVPNNDILEHGFIIKSPKKSFIVYAATSDEREQWMRHIRNCMLQCGGESTYICVYNACSKADSLKSPVWVPDDETETCMVCRVTNFSLITRKHHCRKCGKVVCLKCSQKRFLIPEIS 696
            EAN  RI  ++S FG +  PL    R LIGEG L K+CRK+ K RQFFLF+DILVY   + +  K   QH+ PL  + I+ + +   L +G++IK+P KSF VYAAT+ E+ +WM HI  C+     +S             +  + VWVPD E   CM C+   F+ + R+HHCRKCG VVC  CS+KRFL+P  S
Sbjct:    9 EANTRRISIVESCFGAAGQPLTIPGRVLIGEGVLTKLCRKKPKARQFFLFNDILVYGNIVIQKKKYNKQHIIPLENVTIDSIKDEGELRNGWLIKTPTKSFAVYAATATEKSEWMNHINKCVTDLLSKSG--------KTPSNEHAAVWVPDSEATVCMRCQKAKFTPVNRRHHCRKCGFVVCGPCSEKRFLLPSQS 197
[Close]
BLAST of Pleckstrin homology domain-containing family F member 2-like protein vs. Ensembl Mouse
Match: Plekhf1 (pleckstrin homology domain containing, family F (with FYVE domain) member 1 [Source:MGI Symbol;Acc:MGI:1919537])

HSP 1 Score: 181.03 bits (458), Expect = 3.902e-55
Identity = 92/216 (42.59%), Postives = 130/216 (60.19%), Query Frame = 1 
Query:  106 EANKERIKEIDSLFGNSYPPLYQEKRTLIGEGTLVKVCRKQSKKRQFFLFSDILVYCKYIWKGTKLTSQHVFPLSVMEIEEVPNNDILEHGFIIKSPKKSFIVYAATSDEREQWMRHIRNC----MLQCGGESTYICVYNACSKADSLKSPVWVPDDETETCMVCRVTNFSLITRKHHCRKCGKVVCLKCSQKRFLIPEISCDTVRVCDTCYFVLS 741
            E N +RI  ++S FG S  PL    R L+GEG L K CRK++K R FFLF+DILVY   +    K  SQH+ PL  + +E +P     ++ ++IK+ KKSF+V AA++ ER++W+ HI  C    +L  G + T            +  +  W+PD  T+ CM C  T FS +TR+HHCRKCG VVC +CS++RFL+P +S   +RVC  CY  L+
Sbjct:    9 EINSQRIAAVESCFGASGQPLALPGRVLLGEGVLTKECRKKAKPRIFFLFNDILVYGSIVLSKRKYRSQHIIPLEEVTLEPLPETLQAKNRWMIKTAKKSFVVSAASTTERQEWISHIEECVRRQLLATGRQPT------------TEHAAPWIPDKATDICMRCTQTRFSALTRRHHCRKCGFVVCAECSRERFLLPRLSPKPLRVCSLCYRELA 212
[Close]
BLAST of Pleckstrin homology domain-containing family F member 2-like protein vs. Ensembl Mouse
Match: Fgd6 (FYVE, RhoGEF and PH domain containing 6 [Source:MGI Symbol;Acc:MGI:1261419])

HSP 1 Score: 113.62 bits (283), Expect = 1.320e-27
Identity = 61/204 (29.90%), Postives = 109/204 (53.43%), Query Frame = 1 
Query:  166 LYQEKRTLIGEGTLVKVCRKQSKKRQFFLFSDILVYCKYIWKGT-KLTSQHVFPLSVMEIEEVPNNDILEHGFIIKSPKKSFIVYAATSDEREQWMRHIRNCMLQCGGESTYICVYNACSKAD---------SLKSPVWVPDDETETCMVCRVTNFSLITRKHHCRKCGKVVCLKCSQKRFLIPEISCDTVRVCDTCYFVLSQI 747
            + Q  R  + EGTL+K+ RK  + R FFLF+D L+Y   +  G  KL   ++  L+ M++ + P  +  ++   I+S ++SFI+ A+++ ER+ W+  I + + +   +    C   +  +             K+P+W+PD     CM+C  + F+L  R+HHCR CGK+VC  CS  ++ +  +     RVC+ C+  L ++
Sbjct: 1053 IVQPGRVFLKEGTLMKLSRKVMQPRMFFLFNDALLYTTPMQSGMYKLN--NMLSLAGMKVRK-PTQEAYQNELKIESVERSFILSASSAAERDDWLEAISSSIEEYAKKRITFCPSRSLDEDSERKEEVSPLGAKAPIWIPDTRATMCMIC-TSEFTLTWRRHHCRACGKIVCQACSSNKYGLDYLKGQLARVCEHCFQELQKL 1252
[Close]
BLAST of Pleckstrin homology domain-containing family F member 2-like protein vs. Ensembl Mouse
Match: Fgd4 (FYVE, RhoGEF and PH domain containing 4 [Source:MGI Symbol;Acc:MGI:2183747])

HSP 1 Score: 91.2781 bits (225), Expect = 5.144e-20
Identity = 54/200 (27.00%), Postives = 104/200 (52.00%), Query Frame = 1 
Query:  187 LIGEGTLVKVCRKQ--SKKRQFFLFSDILVYC--KYIWKGTKLTSQHVFPLSVMEIEEVPNNDILEHGFIIKSPKKSFIVYAATSDEREQWMRHIRNCMLQCGGESTYICVYNACSKADSL-----------KSPVWVPDDETETCMVCRVTNFSLITRKHHCRKCGKVVCLKCSQKRFLIPEISCDTVRVCDTCYFVLS 741
            LI EG ++K+  +   +++R  FLF+++L+YC  ++   G+K T +    +  M+I E  +N+   H F I   +++  + A++  ++E+W++ ++  +        +    NA +K + +           ++P W+ D+E   CM C+ +  +L  R+HHCR CG VVC KCS  +  +        +VC  CY ++S
Sbjct:  423 LIKEGQILKLAARNTSAQERYLFLFNNMLLYCVPRFSLVGSKFTVRTRVGIDGMKIVET-HNEEYPHTFQISGKERTLELQASSEQDKEEWIKALQESI--DAFHQRHETFRNAIAKENDIPLEVSTAELGKRAPRWIRDNEVTMCMKCKESFNALTRRRHHCRACGHVVCWKCSDYKAQLEYDGGRLNKVCKDCYQIIS 619
[Close]
BLAST of Pleckstrin homology domain-containing family F member 2-like protein vs. UniProt/SwissProt
Match: sp|O76902|PKHF1_DROME (Pleckstrin homology domain-containing family F member 1 homolog OS=Drosophila melanogaster OX=7227 GN=rush PE=1 SV=1)

HSP 1 Score: 197.593 bits (501), Expect = 3.047e-60
Identity = 93/214 (43.46%), Postives = 129/214 (60.28%), Query Frame = 1 
Query:  106 EANKERIKEIDSLFGNSYPPLYQEKRTLIGEGTLVKVCRKQSKKRQFFLFSDILVYCKYIWKGTKLTSQHVFPLSVMEIEEVPNNDILEHGFIIKSPKKSFIVYAATSDEREQWMRHIRNCMLQCGGESTYICVYNACSKADSLKSPVWVPDDETETCMVCRVTNFSLITRKHHCRKCGKVVCLKCSQKRFLIPEISCDTVRVCDTCYFVLSQI 747
            EAN  RI  +++ FG+S  PL  + R L+GEG L K+CRK+ K RQFFLF+DILVY   +    K   QH+ PL  + +E + +N    +G+ I++  KSF+V+AATS E+++WM HI  C+     +S    V N         + VWVPD +   CM C+ T F+ I R+HHCR CG VVC  CS K+FL+P+ S   +RVCD CY  L  +
Sbjct:    9 EANTRRIASVENCFGSSGVPLAMQGRVLVGEGVLTKMCRKRPKSRQFFLFNDILVYGNIVIGKKKYNKQHIMPLEEVSLESIADNQTYRNGWYIRTTTKSFVVFAATSTEKQEWMAHINKCVEDLLRKSGKKPVEN--------HAAVWVPDTDASVCMHCKKTQFTFIQRRHHCRNCGAVVCAGCSAKKFLLPQQSTKALRVCDACYERLKHV 214
[Close]
BLAST of Pleckstrin homology domain-containing family F member 2-like protein vs. UniProt/SwissProt
Match: sp|Q5ZLY5|PKHF2_CHICK (Pleckstrin homology domain-containing family F member 2 OS=Gallus gallus OX=9031 GN=PLEKHF2 PE=2 SV=1)

HSP 1 Score: 194.512 bits (493), Expect = 5.774e-60
Identity = 95/212 (44.81%), Postives = 129/212 (60.85%), Query Frame = 1 
Query:  106 EANKERIKEIDSLFGNSYPPLYQEKRTLIGEGTLVKVCRKQSKKRQFFLFSDILVYCKYIWKGTKLTSQHVFPLSVMEIEEVPNNDILEHGFIIKSPKKSFIVYAATSDEREQWMRHIRNCMLQCGGESTYICVYNACSKADSLKSPVWVPDDETETCMVCRVTNFSLITRKHHCRKCGKVVCLKCSQKRFLIPEISCDTVRVCDTCYFVLS 741
            EAN  RI  +++ FG +  PL    R LIGEG L K+CRK+ K RQFFLF+DILVY   + +  K   QH+ PL  + I+ + +   L +G++IK+P KSF VYAAT+ E+ +WM HI  C+     +S             +  + VWVPD E   CM C+   F+ + R+HHCRKCG VVC  CS+KRFL+P  S   VR+CD+CY +LS
Sbjct:    9 EANTRRISIVENCFGAAGQPLTIPGRVLIGEGVLTKLCRKKPKARQFFLFNDILVYGNIVIQKKKYNKQHIIPLENVTIDSIQDEGDLRNGWLIKTPTKSFAVYAATATEKSEWMNHINKCVSDLLSKSG--------KTPSNEHAAVWVPDSEATVCMRCQKAKFTPVNRRHHCRKCGFVVCGPCSEKRFLLPSQSSKPVRICDSCYDLLS 212
[Close]
BLAST of Pleckstrin homology domain-containing family F member 2-like protein vs. UniProt/SwissProt
Match: sp|Q91WB4|PKHF2_MOUSE (Pleckstrin homology domain-containing family F member 2 OS=Mus musculus OX=10090 GN=Plekhf2 PE=1 SV=1)

HSP 1 Score: 194.512 bits (493), Expect = 7.567e-60
Identity = 96/212 (45.28%), Postives = 128/212 (60.38%), Query Frame = 1 
Query:  106 EANKERIKEIDSLFGNSYPPLYQEKRTLIGEGTLVKVCRKQSKKRQFFLFSDILVYCKYIWKGTKLTSQHVFPLSVMEIEEVPNNDILEHGFIIKSPKKSFIVYAATSDEREQWMRHIRNCMLQCGGESTYICVYNACSKADSLKSPVWVPDDETETCMVCRVTNFSLITRKHHCRKCGKVVCLKCSQKRFLIPEISCDTVRVCDTCYFVLS 741
            EAN  RI  ++S FG +  PL    R LIGEG L K+CRK+ K RQFFLF+DILVY   + +  K   QH+ PL  + I+ + +   L +G++IK+P KSF VYAAT+ E+ +WM HI  C+     +S             +  + VWVPD E   CM C+   F+ + R+HHCRKCG VVC  CS+KRFL+P  S   VR+CD CY +LS
Sbjct:    9 EANTRRISIVESCFGAAGQPLTIPGRVLIGEGVLTKLCRKKPKARQFFLFNDILVYGNIVIQKKKYNKQHIIPLENVTIDSIKDEGELRNGWLIKTPTKSFAVYAATATEKSEWMNHINKCVTDLLSKSG--------KTPSNEHAAVWVPDSEATVCMRCQKAKFTPVNRRHHCRKCGFVVCGPCSEKRFLLPSQSSKPVRICDFCYDLLS 212
[Close]
BLAST of Pleckstrin homology domain-containing family F member 2-like protein vs. UniProt/SwissProt
Match: sp|Q9H8W4|PKHF2_HUMAN (Pleckstrin homology domain-containing family F member 2 OS=Homo sapiens OX=9606 GN=PLEKHF2 PE=1 SV=1)

HSP 1 Score: 193.741 bits (491), Expect = 1.579e-59
Identity = 95/212 (44.81%), Postives = 128/212 (60.38%), Query Frame = 1 
Query:  106 EANKERIKEIDSLFGNSYPPLYQEKRTLIGEGTLVKVCRKQSKKRQFFLFSDILVYCKYIWKGTKLTSQHVFPLSVMEIEEVPNNDILEHGFIIKSPKKSFIVYAATSDEREQWMRHIRNCMLQCGGESTYICVYNACSKADSLKSPVWVPDDETETCMVCRVTNFSLITRKHHCRKCGKVVCLKCSQKRFLIPEISCDTVRVCDTCYFVLS 741
            EAN  RI  +++ FG +  PL    R LIGEG L K+CRK+ K RQFFLF+DILVY   + +  K   QH+ PL  + I+ + +   L +G++IK+P KSF VYAAT+ E+ +WM HI  C+     +S             +  + VWVPD E   CM C+   F+ + R+HHCRKCG VVC  CS+KRFL+P  S   VR+CD CY +LS
Sbjct:    9 EANTRRISIVENCFGAAGQPLTIPGRVLIGEGVLTKLCRKKPKARQFFLFNDILVYGNIVIQKKKYNKQHIIPLENVTIDSIKDEGDLRNGWLIKTPTKSFAVYAATATEKSEWMNHINKCVTDLLSKSG--------KTPSNEHAAVWVPDSEATVCMRCQKAKFTPVNRRHHCRKCGFVVCGPCSEKRFLLPSQSSKPVRICDFCYDLLS 212
[Close]
BLAST of Pleckstrin homology domain-containing family F member 2-like protein vs. UniProt/SwissProt
Match: sp|Q7ZUV1|PKHF2_DANRE (Pleckstrin homology domain-containing family F member 2 OS=Danio rerio OX=7955 GN=plekhf2 PE=2 SV=1)

HSP 1 Score: 191.045 bits (484), Expect = 1.409e-58
Identity = 97/215 (45.12%), Postives = 130/215 (60.47%), Query Frame = 1 
Query:  106 EANKERIKEIDSLFGNSYPPLYQEKRTLIGEGTLVKVCRKQSKKRQFFLFSDILVYCKYIWKGTKLTSQHVFPLSVMEIEEVPNNDILEHGFIIKSPKKSFIVYAATSDEREQWMRHIRNC---MLQCGGESTYICVYNACSKADSLKSPVWVPDDETETCMVCRVTNFSLITRKHHCRKCGKVVCLKCSQKRFLIPEISCDTVRVCDTCYFVLS 741
            EAN +RI  +++ FG +  PL    R LIGEG L K+CRK+ K RQFFLF+DILVY   + +  K   QH+ PL  + I+ V +   L +G++IK+P KSF VYAAT+ E+ +WM HI  C   +L+  G+S                + VWVPD E   CM C+   F+ + R+HHCRKCG VVC  CS+K+FL+P  S   VRVC+ CY  LS
Sbjct:    9 EANSKRIGVVEACFGTAGQPLAIPGRVLIGEGVLTKLCRKRPKARQFFLFNDILVYGNIVIQKKKYNKQHIIPLESVTIDTVEDEGELRNGWLIKTPTKSFAVYAATATEKSEWMSHINKCVSDLLEKSGKS-----------PTGEHAAVWVPDSEATVCMRCQKMKFTPVNRRHHCRKCGFVVCGPCSEKKFLLPSQSSKPVRVCEFCYKQLS 212
[Close]
BLAST of Pleckstrin homology domain-containing family F member 2-like protein vs. TrEMBL
Match: A0A443RKS4 (Pleckstrin domain-containing family F member 2-like protein OS=Dinothrombium tinctorium OX=1965070 GN=B4U79_06700 PE=4 SV=1)

HSP 1 Score: 202.986 bits (515), Expect = 6.036e-60
Identity = 95/213 (44.60%), Postives = 137/213 (64.32%), Query Frame = 1 
Query:  106 EANKERIKEIDSLFGNSYPPLYQEKRTLIGEGTLVKVCRKQSKKRQFFLFSDILVYCKYIWKGTKLTSQHVFPLSVMEIEEVPNNDILEHGFIIKSPKKSFIVYAATSDEREQWMRHIRNCMLQCGGESTYICVYNACSKADSLKSPVWVPDDETETCMVCRVTNFSLITRKHHCRKCGKVVCLKCSQKRFLIPEISCDTVRVCDTCYFVLSQ 744
            E N  RI  +++ FG S  PL    R L+GEG L K+CRK+ K RQFFLF+DILVY   + KG K + QH+ PL  +++E++ ++D +++G++IK+P KSF VYAAT+ E+++WM+HI+ C+ +         +     +     + VWVPD E   CM C  + FSL+ R+HHCR CG V+C  CS+ +FLIP  S   VRVCDTC+  LS+
Sbjct:    9 EVNHNRIANVENCFGISGVPLNIPGRVLVGEGILTKMCRKKPKPRQFFLFNDILVYGNIVLKGKKYSRQHIIPLEEVKLEDLKDDDAMQNGWLIKTPTKSFAVYAATNTEKQEWMQHIQRCVDE--------LIKRTGKQPTGEHAAVWVPDAEARRCMHCNKSEFSLLNRRHHCRSCGAVICGACSKHKFLIPTQSSKPVRVCDTCFDKLSK 213
[Close]
BLAST of Pleckstrin homology domain-containing family F member 2-like protein vs. TrEMBL
Match: M4AYP1 (Pleckstrin homology domain containing, family F (with FYVE domain) member 2 OS=Xiphophorus maculatus OX=8083 PE=4 SV=1)

HSP 1 Score: 200.675 bits (509), Expect = 6.417e-60
Identity = 100/215 (46.51%), Postives = 134/215 (62.33%), Query Frame = 1 
Query:  106 EANKERIKEIDSLFGNSYPPLYQEKRTLIGEGTLVKVCRKQSKKRQFFLFSDILVYCKYIWKGTKLTSQHVFPLSVMEIEEVPNNDILEHGFIIKSPKKSFIVYAATSDEREQWMRHIRNC---MLQCGGESTYICVYNACSKADSLKSPVWVPDDETETCMVCRVTNFSLITRKHHCRKCGKVVCLKCSQKRFLIPEISCDTVRVCDTCYFVLS 741
            EAN +RI  ++S FG +  PL    R LIGEG L K+CRK+ K RQFFLF+DILVY   + +  K   QH+ PL  + I+ VP++  L +G++IK+P KSF VYAAT+ E+ +WM HI  C   +LQ  G+S                + VWVPD E   CM C+   F+ ++R+HHCRKCG VVC  CS+K+FL+P  S   VRVC+ CY +LS
Sbjct:    9 EANSKRIGLVESCFGAAGQPLAIPGRVLIGEGVLTKLCRKKPKARQFFLFNDILVYGNIVIQKKKYNKQHIIPLEGVTIDTVPDDGELRNGWLIKTPTKSFAVYAATATEKSEWMNHIGKCVRELLQKSGKS-----------PTGEHAAVWVPDSEATVCMRCKKVKFTPVSRRHHCRKCGYVVCGPCSEKKFLLPSQSSKPVRVCEHCYGMLS 212
[Close]
BLAST of Pleckstrin homology domain-containing family F member 2-like protein vs. TrEMBL
Match: A0A139WEK4 (Pleckstrin homology domain-containing family F member 2-like protein OS=Tribolium castaneum OX=7070 GN=TcasGA2_TC034798 PE=4 SV=1)

HSP 1 Score: 201.445 bits (511), Expect = 7.080e-60
Identity = 102/225 (45.33%), Postives = 137/225 (60.89%), Query Frame = 1 
Query:  106 EANKERIKEIDSLFGNSYPPLYQEKRTLIGEGTLVKVCRKQSKKRQFFLFSDILVYCKYIWKGTKLTSQHVFPLSVMEIEEVPNNDILEHGFIIKSPKKSFIVYAATSDEREQWMRHIRNCMLQCGGESTYICVYNACSKADSLKSPVWVPDDETETCMVCRVTNFSLITRKHHCRKCGKVVCLKCSQKRFLIPEISCDTVRVCDTCYFVLSQIQ*MI*SDHNSS 780
            EAN  RI  ++S FGNS  PL    R L+GEG LVK+CRK+ K RQFFLF+DILVY   I    K   QH+ PL  +++E + +++   +G++I++  KSF VYAAT+ E+++WM HI  C+           +  +  KA    + VWVPD E   CM C+ T F+LI R+HHCRKCG VVC  CS KRFL+P  S   +RVC  CY VL+        +HNS+
Sbjct:    9 EANTRRIATVESCFGNSGQPLEVPGRVLVGEGVLVKMCRKKPKTRQFFLFNDILVYGNIIINKKKYNKQHIIPLEEVKLENLEDDNQFRNGWLIRTASKSFAVYAATAVEKQEWMAHINKCIED--------LLRKSGKKAVEEHAAVWVPDGEAPVCMHCKKTQFTLINRRHHCRKCGAVVCGPCSNKRFLLPNQSSKPLRVCLHCYDVLTSAA----KNHNSA 221
[Close]
BLAST of Pleckstrin homology domain-containing family F member 2-like protein vs. TrEMBL
Match: A0A3B5L4I8 (Pleckstrin homology domain containing, family F (with FYVE domain) member 2 OS=Xiphophorus couchianus OX=32473 PE=4 SV=1)

HSP 1 Score: 200.29 bits (508), Expect = 8.322e-60
Identity = 100/215 (46.51%), Postives = 134/215 (62.33%), Query Frame = 1 
Query:  106 EANKERIKEIDSLFGNSYPPLYQEKRTLIGEGTLVKVCRKQSKKRQFFLFSDILVYCKYIWKGTKLTSQHVFPLSVMEIEEVPNNDILEHGFIIKSPKKSFIVYAATSDEREQWMRHIRNC---MLQCGGESTYICVYNACSKADSLKSPVWVPDDETETCMVCRVTNFSLITRKHHCRKCGKVVCLKCSQKRFLIPEISCDTVRVCDTCYFVLS 741
            EAN +RI  ++S FG +  PL    R LIGEG L K+CRK+ K RQFFLF+DILVY   + +  K   QH+ PL  + I+ VP++  L +G++IK+P KSF VYAAT+ E+ +WM HI  C   +LQ  G+S                + VWVPD E   CM C+   F+ ++R+HHCRKCG VVC  CS+K+FL+P  S   VRVC+ CY +LS
Sbjct:    9 EANSKRIGLVESCFGAAGQPLAIPGRVLIGEGVLTKLCRKKPKARQFFLFNDILVYGNIVIQKKKYNKQHIIPLEGVTIDTVPDDGELRNGWLIKTPTKSFAVYAATATEKSEWMNHIGKCVRELLQKSGKS-----------PTGEHAAVWVPDSEATVCMRCKKVKFTPVSRRHHCRKCGYVVCGPCSEKKFLLPSQSSKPVRVCEHCYRMLS 212
[Close]
BLAST of Pleckstrin homology domain-containing family F member 2-like protein vs. TrEMBL
Match: A0A3Q2G3D4 (Pleckstrin homology domain containing, family F (with FYVE domain) member 2 OS=Cyprinodon variegatus OX=28743 PE=4 SV=1)

HSP 1 Score: 200.29 bits (508), Expect = 8.490e-60
Identity = 100/215 (46.51%), Postives = 132/215 (61.40%), Query Frame = 1 
Query:  106 EANKERIKEIDSLFGNSYPPLYQEKRTLIGEGTLVKVCRKQSKKRQFFLFSDILVYCKYIWKGTKLTSQHVFPLSVMEIEEVPNNDILEHGFIIKSPKKSFIVYAATSDEREQWMRHIRNC---MLQCGGESTYICVYNACSKADSLKSPVWVPDDETETCMVCRVTNFSLITRKHHCRKCGKVVCLKCSQKRFLIPEISCDTVRVCDTCYFVLS 741
            EAN +RI  ++S FG +  PL    R LIGEG L K+CRK+ K RQFFLF+DILVY   + +  K   QH+ PL  + I+ VP+   L +G++IK+P KSF VYAAT+ E+ +WM HI  C   +LQ  G+S                + VWVPD E   CM C+   F+ ++R+HHCRKCG VVC  CS K+FL+P  S   VRVC+ CY +LS
Sbjct:    9 EANSKRIGLVESCFGAAGQPLAIPGRVLIGEGVLTKLCRKKPKARQFFLFNDILVYGNIVIQKKKYNKQHIIPLESVTIDTVPDEGELRNGWLIKTPTKSFAVYAATATEKSEWMNHIGKCVRELLQKSGKS-----------PTGEHAAVWVPDSEATVCMRCKKVKFTAVSRRHHCRKCGYVVCGPCSDKKFLLPSQSSKPVRVCEHCYAMLS 212
[Close]
BLAST of Pleckstrin homology domain-containing family F member 2-like protein vs. Ensembl Cavefish
Match: plekhf2 (pleckstrin homology and FYVE domain containing 2 [Source:NCBI gene;Acc:103028556])

HSP 1 Score: 192.586 bits (488), Expect = 3.549e-60
Identity = 97/215 (45.12%), Postives = 130/215 (60.47%), Query Frame = 1 
Query:  106 EANKERIKEIDSLFGNSYPPLYQEKRTLIGEGTLVKVCRKQSKKRQFFLFSDILVYCKYIWKGTKLTSQHVFPLSVMEIEEVPNNDILEHGFIIKSPKKSFIVYAATSDEREQWMRHIRNC---MLQCGGESTYICVYNACSKADSLKSPVWVPDDETETCMVCRVTNFSLITRKHHCRKCGKVVCLKCSQKRFLIPEISCDTVRVCDTCYFVLS 741
            EAN +RI  ++  FG +  PL    R LIGEG L K+CRK+ K RQFFLF+DILVY   + +  K   QH+ PL  + I+ V +   L +G++IK+P KSF VYAAT+ E+ +WM HI  C   +L+  G+S                + VWVPD E   CM C+   F+ ++R+HHCRKCG VVC  CS+K+FL+P  S   VRVC+ CY  LS
Sbjct:    9 EANSKRIAVVEGCFGTAGQPLAIPGRVLIGEGVLTKLCRKKPKARQFFLFNDILVYGNIVIQKKKYNKQHIIPLESVTIDTVADEGDLRNGWLIKTPTKSFAVYAATATEKSEWMNHISKCVSDLLEKSGKS-----------PTGEHAAVWVPDSEASVCMRCQKVKFTPVSRRHHCRKCGFVVCGPCSEKKFLLPSQSSKPVRVCEFCYEQLS 212
[Close]
BLAST of Pleckstrin homology domain-containing family F member 2-like protein vs. Ensembl Cavefish
Match: PLEKHF1 (pleckstrin homology and FYVE domain containing 1 [Source:NCBI gene;Acc:103028531])

HSP 1 Score: 145.591 bits (366), Expect = 1.820e-41
Identity = 76/208 (36.54%), Postives = 120/208 (57.69%), Query Frame = 1 
Query:  112 NKERIKEIDSLFGNSYPPLYQEKRTLIGEGTLVKVCRKQSKKRQFFLFSDILVYCKYIWKGTKLTSQHVFPLSVMEIEEVPNNDILEHGFIIKSPKKSFIVYAATSDEREQWMRHIRNCM---LQCGGESTYICVYNACSKADSLKSPVWVPDDETETCMVCRVTNFSLITRKHHCRKCGKVVCLKCSQKRFLIPEISCDTVRVCDTC 726
            N+ERI+ + S FG S   L +  R L+GEG L+K+C+++ + R FFLF+DILVY   +  G     Q +  L  +E E++ ++  + + +++K+P+KSF V AA+++E++ WM HI NC    LQ  G    +           + +  W+PD  +  CM C  + F++  R+HHCR CG +VC  CS+ R ++  IS   VRVC  C
Sbjct:   11 NRERIQAVASSFGPSGRSLMEPGRVLVGEGRLIKLCKRRPQPRSFFLFNDILVYGSIVMGGRWNKKQQIIRLEEVEQEDLEDSAQMCNQWLLKTPRKSFYVAAASAEEKQAWMEHIENCRNLKLQSLGRPVNV---------QPVFAATWIPDHASAICMRC-SSRFTVTHRRHHCRCCGFIVCNSCSKARVVLKNISNKPVRVCGLC 208
[Close]
BLAST of Pleckstrin homology domain-containing family F member 2-like protein vs. Ensembl Cavefish
Match: fgd6 (FYVE, RhoGEF and PH domain containing 6 [Source:NCBI gene;Acc:103037109])

HSP 1 Score: 119.398 bits (298), Expect = 1.238e-29
Identity = 70/207 (33.82%), Postives = 116/207 (56.04%), Query Frame = 1 
Query:  151 NSYPPLYQEKRTLIGEGTLVKVCRKQSKKRQFFLFSDILVYCKYIWKGT-KLTSQHVFPLSVMEIEEVPNNDILEHGFIIKSPKKSFIVYAATSDEREQWMRHIRNCMLQCGGES-TYICVYNACSKADSL-------KSPVWVPDDETETCMVCRVTNFSLITRKHHCRKCGKVVCLKCSQKRFLIPEISCDTVRVCDTCYFVLSQ 744
            N +  + Q  R  + EGTL+K+ RK  + R FFLF+DIL+Y   +  G  K+ S  +  L+ M++ + P+ +  ++   I+S ++SFI+ A+++ ER++W+  I   +     +  ++I   +  S+  S+       K+P+W+PD  T  CM+C    F+L  R+HHCR CGKVVC  CS  ++ +  +     RVCD CY  L Q
Sbjct:  943 NGHHEIVQPGRVFLKEGTLMKLSRKVMQPRMFFLFNDILLYTTPVQSGQYKVNS--MLSLAGMKVSK-PSLEAYQNELNIESVERSFILSASSATERDEWLEAIATAIEDYTRKKISFISSRSQESEGLSVDGPPLGSKAPIWIPDLRTTMCMIC-TCEFTLTWRRHHCRACGKVVCQACSSNKYYLEYLKNQLARVCDQCYAKLQQ 1145
[Close]
BLAST of Pleckstrin homology domain-containing family F member 2-like protein vs. Ensembl Cavefish
Match: ENSAMXT00000014177.2 (FYVE, RhoGEF and PH domain-containing protein 6-like [Source:NCBI gene;Acc:103024376])

HSP 1 Score: 109.383 bits (272), Expect = 3.132e-26
Identity = 70/221 (31.67%), Postives = 113/221 (51.13%), Query Frame = 1 
Query:  181 RTLIGEGTLVKVCRKQSKKRQFFLFSDILVYCKYIWKGT-KLTSQHVFPLSVMEIEEVPNNDILEHGFIIKSPKKSFIVYAATSDEREQWMRHIRNCM---------------LQCGGESTYICVYNACSKADSLKSPVWVPDDETETCMVCRVTNFSLITRKHHCRKCGKVVCLKCSQKRFLIPEISCDTVRVCDTCYFVLSQIQ*MI*SDHNSSL*TML 795
            RTL+ EGTL+K+ RK  + R FFLF+D L+Y   +  G  KL ++    L+ M++ + P+ +  ++   I+S ++SFI+ A++   R++W+  I   +                + GG+ T      +       K+P+W+PD     CM+C    F+L  R+HHCR CGKVVC  CS  ++ +  +     RVCD C+  L          HNSS  ++L
Sbjct:  836 RTLLKEGTLMKLSRKVMQPRMFFLFNDTLLYTTPLQTGQYKLNNE--LSLAGMKVSK-PSQEGHQNELNIESVERSFILSASSPTARDEWLEAISAAINDYTKKMISFGSSRSPEEGGKDTVDAQLGS-------KAPIWIPDLRATMCMIC-TCEFTLTWRRHHCRACGKVVCQACSTNKYPLEYLKYHPERVCDQCFETLQ---------HNSSGSSIL 1036
[Close]
BLAST of Pleckstrin homology domain-containing family F member 2-like protein vs. Ensembl Cavefish
Match: fgd5a (FYVE, RhoGEF and PH domain-containing protein 5-like [Source:NCBI gene;Acc:103035852])

HSP 1 Score: 97.8265 bits (242), Expect = 2.926e-22
Identity = 62/197 (31.47%), Postives = 100/197 (50.76%), Query Frame = 1 
Query:  166 LYQEKRTLIGEGTLVKVCRKQSKKRQFFLFSDILVYCKYIWKGTKLTSQHVFPLSVMEIEEVPNNDILEHGFIIKSPKKSFIVYAATSDEREQWMRHI-RNCMLQCGGESTYICVYNACSK---ADSLKSPVWVPDDETETCMVCRVTNFSLITRKHHCRKCGKVVCLKCSQKRFLIPEISCDTVRVCDTCYFVLSQ 744
            L Q  R  + EGTL+KV RK  + R  FL +D+++Y  Y  +  K   ++  PLS M++ +   +++L +   I+    +  + A++  ERE W   + R       G +T+     +  K   +    +PV VP      CM C  ++FSL  RKHHC  CGKVVC  CS+ R+ +  +    V+VC+ C+  L +
Sbjct: 1214 LLQPGRVFVKEGTLMKVSRKSRQPRHLFLTNDMMLY-TYPQQDGKYRLKNTLPLSGMKVSKSVIDNVL-NTLRIEVNDVTITLSASSLAEREDWFHTLSRAIADHAAGLNTFSSSSESREKLWMSLGEAAPVLVPISHAMMCMNC-ASDFSLTLRKHHCNACGKVVCRACSRNRYPLKYLKDRAVKVCNRCFAELKK 1407
[Close]
BLAST of Pleckstrin homology domain-containing family F member 2-like protein vs. Ensembl Sea Lamprey
Match: plekhf2 (pleckstrin homology domain containing, family F (with FYVE domain) member 2 [Source:NCBI gene;Acc:393214])

HSP 1 Score: 162.925 bits (411), Expect = 2.587e-49
Identity = 81/208 (38.94%), Postives = 115/208 (55.29%), Query Frame = 1 
Query:  106 EANKERIKEIDSLFGNSYPPLYQEKRTLIGEGTLVKVCRKQSKKRQFFLFSDILVYCKYIWKGTKLTSQHVFPLSVMEIEEVPNNDILEHGFIIKSPKKSFIVYAATSDEREQWMRHIRNCMLQCGGESTYICVYNACSKADSLKSPVWVPDDETETCMVCRVTNFSLITRKHHCRKCGKVVCLKCSQKRFLIPEISCDTVRVCDTCY 729
            E N  RI  I+S FG +  PL    R L+GEGTL K+CRK  K RQFFLF D++VY   +    +  +Q V  L  + I  +P+   L +G+++++P KSF V+AAT  ER +W+ HI  C+ +       +             +  WVPD     CM  + + F+ + R+HHCRKCG VVC  CS +RFL+P  S   +RVC  C+
Sbjct:    9 EENCRRIARIESCFGAAGRPLMAPGRVLVGEGTLTKLCRKGPKPRQFFLFDDMVVYGAAVLGNRRYANQRVLALEAVTICTLPDEGELSNGWLMQTPAKSFKVFAATESERAEWIGHIERCVRE-------LRAKRGLPPHGLEPAAWWVPDSSASACMRRQRSRFNALNRRHHCRKCGIVVCGACSDRRFLLPGQSSRPLRVCIDCF 209
[Close]
BLAST of Pleckstrin homology domain-containing family F member 2-like protein vs. Ensembl Sea Lamprey
Match: ENSPMAT00000005437.1 (pep scaffold:Pmarinus_7.0:GL486528:10206:16522:1 gene:ENSPMAG00000004933.1 transcript:ENSPMAT00000005437.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 82.0333 bits (201), Expect = 2.964e-18
Identity = 56/201 (27.86%), Postives = 102/201 (50.75%), Query Frame = 1 
Query:  187 LIGEGTLVKVCRKQS--KKRQFFLFSDILVYC-KYIWK-GTKLTSQHVFPLSVMEIEEVPNNDILEHGFIIKSPKKSFIVYAATSDEREQWMRHIRNCMLQCGGESTYICVYNACSKAD-----------SLKSPVWVPDDETETCMVCRVTNFSLITRKHHCRKCGKVVCLKCSQKRFLIPEISCDTVRVCDTCYFVLSQ 744
            L+ EG ++K   +    ++R  FLF+++L++C   +W  G + T +    +  +E+++V  +D +   F +   +++    A T +E++ WM+ I N +++   E     + +  + +D             ++P+WV D     CM C+    +L  R+HHCR CGKVVC KCS  R L+        RVC+ CY  L++
Sbjct:   94 LLKEGIILKRSVRIGVPQERYLFLFNNMLLHCVPKLWSMGQRYTLRTRINVRDLEVKDVNQHDQVP-TFQVCGVQRTIDFQARTEEEKQDWMKAI-NEVIKTFREKEETFMGHTANVSDVSPPATQGMELGQRAPMWVRDVNVTLCMTCQDPFTTLTRRRHHCRACGKVVCWKCSDHRVLLAYEPRKLQRVCEACYAQLTE 292
[Close]
BLAST of Pleckstrin homology domain-containing family F member 2-like protein vs. Ensembl Sea Lamprey
Match: eea1 (early endosome antigen 1 [Source:ZFIN;Acc:ZDB-GENE-041111-270])

HSP 1 Score: 66.6254 bits (161), Expect = 1.490e-12
Identity = 28/60 (46.67%), Postives = 35/60 (58.33%), Query Frame = 1 
Query:  550 WVPDDETETCMVCRVTNFSLITRKHHCRKCGKVVCLKCSQKRFLIPEISCDTVRVCDTCY 729
            W  D E + CM C    FS+  RKHHCR CG + C +CS +  +IP      VRVCDTC+
Sbjct: 1307 WAEDGEVQNCMGCG-KGFSVTVRKHHCRHCGNIFCGECSARNSMIPSAK-KPVRVCDTCF 1364
[Close]
BLAST of Pleckstrin homology domain-containing family F member 2-like protein vs. Ensembl Sea Lamprey
Match: ENSPMAT00000001934.1 (pep scaffold:Pmarinus_7.0:GL488632:1056:3278:1 gene:ENSPMAG00000001758.1 transcript:ENSPMAT00000001934.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 60.4622 bits (145), Expect = 7.513e-12
Identity = 29/71 (40.85%), Postives = 40/71 (56.34%), Query Frame = 1 
Query:  532 SLKSPVWVPDDETETCMVCRVTNFSLITRKHHCRKCGKVVCLKCSQKRFLIPEISCDTVRVCDTCYFVLSQ 744
            +L+  VW+ D +   C +C    FS+  RKHHCR CG++ C  CS     +P  S   VRVCD C+ +L Q
Sbjct:   49 ALQGQVWLKDQDATNCKLCE-KEFSISRRKHHCRNCGEIFCNSCSDNELPLPS-SPKPVRVCDLCHALLLQ 117
[Close]
BLAST of Pleckstrin homology domain-containing family F member 2-like protein vs. Ensembl Sea Lamprey
Match: fgd1 (FYVE, RhoGEF and PH domain containing 1 [Source:ZFIN;Acc:ZDB-GENE-081104-33])

HSP 1 Score: 62.7734 bits (151), Expect = 2.376e-11
Identity = 53/203 (26.11%), Postives = 88/203 (43.35%), Query Frame = 1 
Query:  187 LIGEGTLVKVCRKQ--SKKRQFFLFSDILVYCKYIWKGTKLTSQHVFP----LSVMEIEEVPNNDILEHGFIIKSPKKSFIVYAATSDEREQWMRHIRNCMLQCG-----------GESTYICVYNACSKADSL--KSPVWVPDDETETCMVCRVTNFSLITRKHHCRKCGKVVCLKCSQKRFLIPEISCDTVRVCDTCYFVL 738
            LI EG ++K+  K   +++R  FLF+++L+YC       +L  Q  F     L++  ++    +        ++S     I +  +  E+++W++ I N                 G +  + +      A  L  ++P  V +     CM C     +L  RKHHCR CG VVC KCS+ +  +        RVC  CY VL
Sbjct:  452 LIKEGQILKLSAKNGTAQERHLFLFNNMLLYC---VPKLRLMGQQRFSVRTRLNIDGMQYKRTSPAQLPSPTLRSRLHRSIYFYRSEAEKKEWVKAINNSESHQRSQVRVNFKKFIGNNHELYLIPPPHPATELGRRAPHLVRERSVSECMSCSEPFNALTRRKHHCRACGHVVCGKCSEYKAQLEYEGGKLARVCHDCYGVL 651
[Close]
BLAST of Pleckstrin homology domain-containing family F member 2-like protein vs. Ensembl Yeast
Match: VPS27 (Endosomal protein that forms a complex with Hse1p; required for recycling Golgi proteins, forming lumenal membranes and sorting ubiquitinated proteins destined for degradation; has Ubiquitin Interaction Motifs which bind ubiquitin (Ubi4p) [Source:SGD;Acc:S000005289])

HSP 1 Score: 56.6102 bits (135), Expect = 1.450e-9
Identity = 27/66 (40.91%), Postives = 41/66 (62.12%), Query Frame = 1 
Query:  538 KSPV-WVPDDETETCMVCRVTNFSLITRKHHCRKCGKVVCLKCSQKRFLIPEISC-DTVRVCDTCY 729
            K+P  W+   +++ CM+C    FSL+ RKHHCR CG V C + S     +P++   + VRVCD+C+
Sbjct:  165 KTPADWI---DSDACMICS-KKFSLLNRKHHCRSCGGVFCQEHSSNSIPLPDLGIYEPVRVCDSCF 226
[Close]
BLAST of Pleckstrin homology domain-containing family F member 2-like protein vs. Ensembl Yeast
Match: PIB1 (RING-type ubiquitin ligase of the endosomal and vacuolar membranes; binds phosphatidylinositol(3)-phosphate; contains a FYVE finger domain [Source:SGD;Acc:S000002721])

HSP 1 Score: 47.7506 bits (112), Expect = 8.083e-7
Identity = 18/41 (43.90%), Postives = 27/41 (65.85%), Query Frame = 1 
Query:  550 WVPDDETETCMVCRVTNFSLITRKHHCRKCGKVVCLKCSQK 672
            W  D+E  +C  C+ TNFS + R+HHCR CG++ C  C++ 
Sbjct:   14 WQADEEAHSCFQCK-TNFSFLVRRHHCRCCGRIFCSSCTEN 53
[Close]
BLAST of Pleckstrin homology domain-containing family F member 2-like protein vs. Ensembl Nematostella
Match: EDO38501 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SCW3])

HSP 1 Score: 197.978 bits (502), Expect = 6.751e-63
Identity = 99/217 (45.62%), Postives = 133/217 (61.29%), Query Frame = 1 
Query:  106 EANKERIKEIDSLFGNSYPPLYQEK--RTLIGEGTLVKVCRKQSKKRQFFLFSDILVYCKYIWKGTKLTSQHVFPLSVMEIEEVPNNDILEHGFIIKSPKKSFIVYAATSDEREQWMRHIRNCMLQCGGESTYICVYNACSKADSLKSPVWVPDDETETCMVCRVTNFSLITRKHHCRKCGKVVCLKCSQKRFLIPEISCDTVRVCDTCYFVLSQIQ 750
            EANK RI+ + S FG+S  PL+ E   R L+GEG L K+CRK+ K RQFFLF+DILVY   +    K   QH+ PL  +++  + ++  L++G+ I S KKSF VYAAT+ E+ +WM HI  C+           +     KA  + + VWVPD E  TCM C  T F+ I R+HHCRKCG VVC  CS K+FL+P  S   +RVC++CY  LS  +
Sbjct:    9 EANKRRIQHVQSCFGSSGQPLWLENKSRVLVGEGVLTKLCRKKPKPRQFFLFNDILVYGNIVINKKKYNKQHIIPLEEIKLLTLEDDGNLKNGWQIISTKKSFAVYAATATEKAEWMAHINKCIQD--------LLAKTGKKAGGVHAAVWVPDSEASTCMSCMKTKFTAINRRHHCRKCGAVVCGACSTKKFLLPAQSSKPLRVCNSCYNTLSNTK 217
[Close]
BLAST of Pleckstrin homology domain-containing family F member 2-like protein vs. Ensembl Nematostella
Match: EDO48232 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RKE8])

HSP 1 Score: 113.235 bits (282), Expect = 2.233e-28
Identity = 64/192 (33.33%), Postives = 98/192 (51.04%), Query Frame = 1 
Query:  181 RTLIGEGTLVKVCRKQSKKRQFFLFSDILVYCKYIWKGTKLTSQHVFPLSVMEIEEVPNNDILEHGFIIKSPKKSFIVYAATSDEREQWMRHIRNCMLQCGGESTYICVYNACSKADSL------KSPVWVPDDETETCMVCRVTNFSLITRKHHCRKCGKVVCLKCSQKRFLIPEISCDTVRVCDTCYFVL 738
            R  I +G L+K+CRK  ++R FFL +D+L+Y   +  G +   +   PL  M++  +P +    + F I S  +SF + A+TS ER++W+  +   +     +             DS       K+PVW+PD     CM+C   +F++  R+HHCR CGKVVC  CS     +  +     RVCD CY VL
Sbjct:  214 REFIKQGNLLKLCRKDMQERTFFLLTDVLLYTAPV-GGNQYKLRETLPLLGMKVI-LPESQEFVNEFSIISTTRSFTLSASTSAERDEWLEELERAINAMTKKKISFFKSKEGITQDSEDTKLGEKAPVWIPDARVTMCMLC-TDDFTVTNRRHHCRGCGKVVCGSCSDNLAPLTYLDYAQARVCDMCYEVL 402
[Close]
BLAST of Pleckstrin homology domain-containing family F member 2-like protein vs. Ensembl Nematostella
Match: EDO44864 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RUJ2])

HSP 1 Score: 65.4698 bits (158), Expect = 2.473e-12
Identity = 33/85 (38.82%), Postives = 49/85 (57.65%), Query Frame = 1 
Query:  502 CVYNACSKADSL----KSPVWVPDDETETCMVCRVTNFSLITRKHHCRKCGKVVCLKCSQKRFLIPEISCD-TVRVCDTCYFVLS 741
            C + A +++D++     +P W    E + C +CRV  F    R+HHCR CG+V C KCS K  +IP+   +  VRVCD CY  ++
Sbjct:  141 CKFPAFNESDAMFSADSAPAWA---EGDVCHMCRV-KFGTFIRQHHCRNCGQVFCKKCSSKESIIPQFGIEKEVRVCDPCYLKIN 221
[Close]
BLAST of Pleckstrin homology domain-containing family F member 2-like protein vs. Ensembl Nematostella
Match: EDO49099 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RI68])

HSP 1 Score: 60.8474 bits (146), Expect = 1.759e-10
Identity = 26/46 (56.52%), Postives = 31/46 (67.39%), Query Frame = 1 
Query:  547 VWVPDDETETCMVCRVTNFSLITRKHHCRKCGKVVCLKCSQKRFLI 684
             WVPD E +TCM C+ T F+ + R+HHCRKCG V C  CS KR  I
Sbjct:  533 AWVPDQEVKTCMACK-TRFTTVRRRHHCRKCGGVFCGACSSKRVPI 577
[Close]
BLAST of Pleckstrin homology domain-containing family F member 2-like protein vs. Ensembl Nematostella
Match: EDO49533 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RGJ2])

HSP 1 Score: 54.299 bits (129), Expect = 3.617e-10
Identity = 26/60 (43.33%), Postives = 38/60 (63.33%), Query Frame = 1 
Query:  550 WVPDDETETCMVCRVTNFSLITRKHHCRKCGKVVCLKCSQKRFLIPEISC-DTVRVCDTC 726
            W+ DDE   C +C    F+ I RKHHCR+CG+V+C KC  ++  +P++   D  R+CD C
Sbjct:    1 WMSDDEAHVCPLC-SQKFTQIRRKHHCRQCGRVLCNKCCNEKVPLPQMGFEDPERICDYC 59
[Close]
BLAST of Pleckstrin homology domain-containing family F member 2-like protein vs. Ensembl Medaka
Match: plekhf2 (pleckstrin homology and FYVE domain containing 2 [Source:NCBI gene;Acc:101160441])

HSP 1 Score: 196.052 bits (497), Expect = 1.868e-61
Identity = 102/227 (44.93%), Postives = 134/227 (59.03%), Query Frame = 1 
Query:  106 EANKERIKEIDSLFGNSYPPLYQEKRTLIGEGTLVKVCRKQSKKRQFFLFSDILVYCKYIWKGTKLTSQHVFPLSVMEIEEVPNNDILEHGFIIKSPKKSFIVYAATSDEREQWMRHIRNC---MLQCGGESTYICVYNACSKADSLKSPVWVPDDETETCMVCRVTNFSLITRKHHCRKCGKVVCLKCSQKRFLIPEISCDTVRVCDTCYFVLSQIQ*MI*SDHNS 777
            EAN +RI  ++S FG +  PL    R LIGEG L K+CRK+ K RQFFLF+DILVY   + +  K   QH+ PL  + I+ VP+   L +G++IK+P KSF VYAAT+ E+ +WM HI  C   +LQ  G+S                + VWVPD E   CM C    F+ + R+HHCRKCG VVC  CS+K++L+P  S   VRVC+ CY  L+       SD NS
Sbjct:    9 EANSKRIGMVESCFGAAGQPLAIPGRVLIGEGVLTKLCRKKPKARQFFLFNDILVYGNIVIQKKKYNKQHIIPLESVTIDTVPDEGDLRNGWLIKTPTKSFAVYAATATEKCEWMNHIGKCVKDLLQKSGKS-----------PTGEHAAVWVPDSEASVCMRCLKVKFTAVNRRHHCRKCGYVVCNPCSEKKYLLPSQSSKPVRVCEFCYAQLTSGSLAPCSDSNS 224
[Close]
BLAST of Pleckstrin homology domain-containing family F member 2-like protein vs. Ensembl Medaka
Match: ENSORLT00000040317.1 (pleckstrin homology domain-containing family F member 1-like [Source:NCBI gene;Acc:101175000])

HSP 1 Score: 137.887 bits (346), Expect = 5.430e-39
Identity = 81/209 (38.76%), Postives = 118/209 (56.46%), Query Frame = 1 
Query:  112 NKERIKEIDSLFGNSYPPLYQEKRTLIGEGTLVKVCRKQSKKRQFFLFSDILVYCKYIWKGTKLTSQHVFPLSVMEIEEVPNNDILEHGFIIKSPKKSFIVYAATSDEREQWMRHIRNC---MLQCGGESTYICVYNACSKADSLKSPVWVPDDETETCMVCRVTNFSLITRKHHCRKCGKVVCLKCSQKRFLIPEISCDT-VRVCDTC 726
            N+  I E+D  F     PL Q  R L+G+G+L+K  RK+   + FFLF+D+LVY   I K      Q V  L  +++E++ +++  +H ++I SP KSF V A + +E++ WM HI  C   +LQ GG          C+ + S  +P W+PD  ++ CM C  T FSL  RKHHCR CG +VC +CS+ R +I  +     VRVC  C
Sbjct:   10 NRRLIGELDKSFSPPRQPLLQPGRVLLGKGSLMKQGRKKWDLKAFFLFNDVLVYGSIIMKDRWFKKQKVIRLEDIKMEDLEDSEDFKHQWLICSPTKSFFVSALSLEEKKAWMEHIEECRRNLLQGGG----------CTPS-SRYAPTWIPDHVSQRCMRC-FTIFSLSKRKHHCRSCGFLVCSQCSKARAVIDALHPKKEVRVCKLC 206
[Close]
BLAST of Pleckstrin homology domain-containing family F member 2-like protein vs. Ensembl Medaka
Match: ENSORLT00000018711.2 (pleckstrin homology domain-containing family F member 1-like [Source:NCBI gene;Acc:101175000])

HSP 1 Score: 137.887 bits (346), Expect = 8.708e-39
Identity = 81/209 (38.76%), Postives = 118/209 (56.46%), Query Frame = 1 
Query:  112 NKERIKEIDSLFGNSYPPLYQEKRTLIGEGTLVKVCRKQSKKRQFFLFSDILVYCKYIWKGTKLTSQHVFPLSVMEIEEVPNNDILEHGFIIKSPKKSFIVYAATSDEREQWMRHIRNC---MLQCGGESTYICVYNACSKADSLKSPVWVPDDETETCMVCRVTNFSLITRKHHCRKCGKVVCLKCSQKRFLIPEISCDT-VRVCDTC 726
            N+  I E+D  F     PL Q  R L+G+G+L+K  RK+   + FFLF+D+LVY   I K      Q V  L  +++E++ +++  +H ++I SP KSF V A + +E++ WM HI  C   +LQ GG          C+ + S  +P W+PD  ++ CM C  T FSL  RKHHCR CG +VC +CS+ R +I  +     VRVC  C
Sbjct:   11 NRRLIGELDKSFSPPRQPLLQPGRVLLGKGSLMKQGRKKWDLKAFFLFNDVLVYGSIIMKDRWFKKQKVIRLEDIKMEDLEDSEDFKHQWLICSPTKSFFVSALSLEEKKAWMEHIEECRRNLLQGGG----------CTPS-SRYAPTWIPDHVSQRCMRC-FTIFSLSKRKHHCRSCGFLVCSQCSKARAVIDALHPKKEVRVCKLC 207
[Close]
BLAST of Pleckstrin homology domain-containing family F member 2-like protein vs. Ensembl Medaka
Match: FGD6 (FYVE, RhoGEF and PH domain-containing protein 6 [Source:NCBI gene;Acc:101155348])

HSP 1 Score: 123.635 bits (309), Expect = 3.685e-31
Identity = 66/200 (33.00%), Postives = 110/200 (55.00%), Query Frame = 1 
Query:  166 LYQEKRTLIGEGTLVKVCRKQSKKRQFFLFSDILVYCKYIWKGTKLTSQHVFPLSVMEIEEVPNNDILEHGFIIKSPKKSFIVYAATSDEREQWMRHIRNCMLQCGGESTYICVYNACSKAD-------SLKSPVWVPDDETETCMVCRVTNFSLITRKHHCRKCGKVVCLKCSQKRFLIPEISCDTVRVCDTCYFVLSQ 744
            + Q  R    EG L+K+ RK  + R FFLF+DIL+Y K +  G +   +++  L+ M++ + PN +  ++   I+S ++SFI+ A+++ ER+ W+  I   +     +       N  ++AD         K+P+W+PD  T  CM+C  + F+L  R+HHCR CGKV+C  CS  +  +  +   + RVCD C+  L Q
Sbjct:  841 IIQPGRIFFKEGILMKLSRKVMQPRMFFLFNDILLYTKPVQTG-QYKLKNMLSLAGMKVSK-PNQEAYQNELNIESVERSFILSASSATERDDWLNSISAAINDFTKKKITFLSGNPANEADLTDGTPLGSKAPIWIPDPRTTMCMIC-TSEFTLTWRRHHCRACGKVICQGCSSNKHYLQYMK-KSDRVCDLCFQTLRQ 1036
[Close]
BLAST of Pleckstrin homology domain-containing family F member 2-like protein vs. Ensembl Medaka
Match: FGD6 (FYVE, RhoGEF and PH domain-containing protein 6 [Source:NCBI gene;Acc:101155348])

HSP 1 Score: 123.635 bits (309), Expect = 3.686e-31
Identity = 66/200 (33.00%), Postives = 110/200 (55.00%), Query Frame = 1 
Query:  166 LYQEKRTLIGEGTLVKVCRKQSKKRQFFLFSDILVYCKYIWKGTKLTSQHVFPLSVMEIEEVPNNDILEHGFIIKSPKKSFIVYAATSDEREQWMRHIRNCMLQCGGESTYICVYNACSKAD-------SLKSPVWVPDDETETCMVCRVTNFSLITRKHHCRKCGKVVCLKCSQKRFLIPEISCDTVRVCDTCYFVLSQ 744
            + Q  R    EG L+K+ RK  + R FFLF+DIL+Y K +  G +   +++  L+ M++ + PN +  ++   I+S ++SFI+ A+++ ER+ W+  I   +     +       N  ++AD         K+P+W+PD  T  CM+C  + F+L  R+HHCR CGKV+C  CS  +  +  +   + RVCD C+  L Q
Sbjct:  843 IIQPGRIFFKEGILMKLSRKVMQPRMFFLFNDILLYTKPVQTG-QYKLKNMLSLAGMKVSK-PNQEAYQNELNIESVERSFILSASSATERDDWLNSISAAINDFTKKKITFLSGNPANEADLTDGTPLGSKAPIWIPDPRTTMCMIC-TSEFTLTWRRHHCRACGKVICQGCSSNKHYLQYMK-KSDRVCDLCFQTLRQ 1038
[Close]
BLAST of Pleckstrin homology domain-containing family F member 2-like protein vs. Planmine SMEST
Match: SMESG000038764.1 (SMESG000038764.1)

HSP 1 Score: 197.208 bits (500), Expect = 6.544e-62
Identity = 99/207 (47.83%), Postives = 139/207 (67.15%), Query Frame = 1 
Query:  109 ANKERIKEIDSLFGNSYPPLYQEKRTLIGEGTLVKVCRKQSKKRQFFLFSDILVYCKYIWKGTKLTSQHVFPLSVMEIEEVPNNDILEHGFIIKSPKKSFIVYAATSDEREQWMRHIRNCMLQCGGESTYICVYNACSKADSLKSPVWVPDDETETCMVCRVTNFSLITRKHHCRKCGKVVCLKCSQKRFLIPEISCDTVRVCDTCY 729
            ++ ERI EI+++FG S  PL Q  R LIGEG L+K+CRK+ K+R FFLFSDILVY   +  G KL  QH+  +  +EI ++ ++ I  +GF +KSPKKSF +YA +++E+EQWM H++ C+ +C  +   + +        + KSPVW+PD     CMVCR+T F+++ R+HHCR CG VVC  CS KR+L+P  S   VRVCD CY
Sbjct:    4 SSDERIIEIENMFGLSGIPLSQVDRKLIGEGILMKMCRKKPKERHFFLFSDILVYGSIVVHGKKLVGQHIIEIEEVEISDLSDDIIPYYGFCVKSPKKSFAMYAVSAEEKEQWMNHLQKCIDECSKKRGLVGL-------SATKSPVWIPDALAPKCMVCRLTVFAVLNRRHHCRHCGVVVCSTCSLKRWLLPYQSPVPVRVCDLCY 203
[Close]
BLAST of Pleckstrin homology domain-containing family F member 2-like protein vs. Planmine SMEST
Match: SMESG000028452.1 (SMESG000028452.1)

HSP 1 Score: 190.274 bits (482), Expect = 1.358e-59
Identity = 100/221 (45.25%), Postives = 135/221 (61.09%), Query Frame = 1 
Query:  121 RIKEIDSLFGNSYPPLYQEKRTLIGEGTLVKVCRKQSKKRQFFLFSDILVYCKYIWKGTKLTSQHVFPLSVMEIEEVPNNDILEHGFIIKSPKKSFIVYAATSDEREQWMRHIRNCMLQCGGESTYICVYNACSKADSLK-SPVWVPDDETETCMVCRVTNFSLITRKHHCRKCGKVVCLKCSQKRFLIPEISCDTVRVCDTCYFVLSQIQ*MI*SDHNSS 780
            RIK +++LFG +  PLY   R LIGEG L K+CR++ K+R FFLF+DILVY   I    KLTSQH+F L  + +EEV  N+     F + +PKKSFI+ A + DER QW+ HIR    +C  ++         S+   +   PVW+PD E   CM C +T FS I R+HHCR CG VVC KCSQ++ ++P  S + +RVC  C+     +Q  I  D+NSS
Sbjct:   10 RIKYVENLFGVNGMPLYNSNRELIGEGVLFKLCRRKPKQRHFFLFNDILVYGNIILYKKKLTSQHIFELESLTVEEVKGNENFPFQFKVMTPKKSFIICAVSEDERTQWILHIRKYSKECETKTL--------SRNKPVGFCPVWIPDTEAMKCMTCNLTEFSWIQRRHHCRSCGNVVCAKCSQQKIILPNQSHNALRVCVRCF-----LQNNIKIDNNSS 217
[Close]
BLAST of Pleckstrin homology domain-containing family F member 2-like protein vs. Planmine SMEST
Match: SMESG000038764.1 (SMESG000038764.1)

HSP 1 Score: 186.808 bits (473), Expect = 4.431e-58
Identity = 94/196 (47.96%), Postives = 130/196 (66.33%), Query Frame = 1 
Query:  142 LFGNSYPPLYQEKRTLIGEGTLVKVCRKQSKKRQFFLFSDILVYCKYIWKGTKLTSQHVFPLSVMEIEEVPNNDILEHGFIIKSPKKSFIVYAATSDEREQWMRHIRNCMLQCGGESTYICVYNACSKADSLKSPVWVPDDETETCMVCRVTNFSLITRKHHCRKCGKVVCLKCSQKRFLIPEISCDTVRVCDTCY 729
            +FG S  PL Q  R LIGEG L+K+CRK+ K+R FFLFSDILVY   +  G KL  QH+  +  +EI ++ ++ I  +GF +KSPKKSF +YA +++E+EQWM H++ C+ +C  +   + +        + KSPVW+PD     CMVCR+T F+++ R+HHCR CG VVC  CS KR+L+P  S   VRVCD CY
Sbjct:    1 MFGLSGIPLSQVDRKLIGEGILMKMCRKKPKERHFFLFSDILVYGSIVVHGKKLVGQHIIEIEEVEISDLSDDIIPYYGFCVKSPKKSFAMYAVSAEEKEQWMNHLQKCIDECSKKRGLVGL-------SATKSPVWIPDALAPKCMVCRLTVFAVLNRRHHCRHCGVVVCSTCSLKRWLLPYQSPVPVRVCDLCY 189
[Close]
BLAST of Pleckstrin homology domain-containing family F member 2-like protein vs. Planmine SMEST
Match: SMESG000066383.1 (SMESG000066383.1)

HSP 1 Score: 62.7734 bits (151), Expect = 1.064e-10
Identity = 29/81 (35.80%), Postives = 47/81 (58.02%), Query Frame = 1 
Query:  502 CVYNACSKADSL----KSPVWVPDDETETCMVCRVTNFSLITRKHHCRKCGKVVCLKCSQKRFLIPEISCDT-VRVCDTCY 729
            C +    ++D++     +P W    + +TC  C++  FS + RKHHCR CG + C +C+ KR  IP+   +  VRVC++CY
Sbjct:  140 CTFPTLIESDAMFVSETAPEW---QDADTCYRCKIA-FSALKRKHHCRHCGNIFCDECTSKRSNIPKYGIEKEVRVCESCY 216
[Close]
BLAST of Pleckstrin homology domain-containing family F member 2-like protein vs. Planmine SMEST
Match: SMESG000066383.1 (SMESG000066383.1)

HSP 1 Score: 62.3882 bits (150), Expect = 1.204e-10
Identity = 29/81 (35.80%), Postives = 47/81 (58.02%), Query Frame = 1 
Query:  502 CVYNACSKADSL----KSPVWVPDDETETCMVCRVTNFSLITRKHHCRKCGKVVCLKCSQKRFLIPEISCDT-VRVCDTCY 729
            C +    ++D++     +P W    + +TC  C++  FS + RKHHCR CG + C +C+ KR  IP+   +  VRVC++CY
Sbjct:  140 CTFPTLIESDAMFVSETAPEW---QDADTCYRCKIA-FSALKRKHHCRHCGNIFCDECTSKRSNIPKYGIEKEVRVCESCY 216
The following BLAST results are available for this feature:
BLAST of Pleckstrin homology domain-containing family F member 2-like protein vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5
Match NameE-valueIdentityDescription
PLEKHF23.287e-6044.81pleckstrin homology and FYVE domain containing 2 [... [more]
PLEKHF23.287e-6044.81pleckstrin homology and FYVE domain containing 2 [... [more]
PLEKHF15.622e-5543.54pleckstrin homology and FYVE domain containing 1 [... [more]
PLEKHF15.622e-5543.54pleckstrin homology and FYVE domain containing 1 [... [more]
FGD61.487e-3130.48FYVE, RhoGEF and PH domain containing 6 [Source:HG... [more]
back to top
BLAST of Pleckstrin homology domain-containing family F member 2-like protein vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 5
Match NameE-valueIdentityDescription
ZK632.127.179e-5641.98pep chromosome:WBcel235:III:9830802:9832378:1 gene... [more]
ZK632.127.179e-5641.98pep chromosome:WBcel235:III:9830792:9832430:1 gene... [more]
aka-11.186e-1340.00A Kinase Anchor protein [Source:UniProtKB/TrEMBL;... [more]
aka-11.186e-1340.00A Kinase Anchor protein [Source:UniProtKB/TrEMBL;... [more]
aka-11.682e-1137.33A Kinase Anchor protein [Source:UniProtKB/TrEMBL;... [more]
back to top
BLAST of Pleckstrin homology domain-containing family F member 2-like protein vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5
Match NameE-valueIdentityDescription
rush3.039e-6143.46gene:FBgn0025381 transcript:FBtr0070259[more]
rush3.039e-6143.46gene:FBgn0025381 transcript:FBtr0339589[more]
Sara5.048e-1544.93gene:FBgn0026369 transcript:FBtr0071641[more]
CG60512.341e-1240.54gene:FBgn0039492 transcript:FBtr0339264[more]
CG60512.341e-1240.54gene:FBgn0039492 transcript:FBtr0305050[more]
back to top
BLAST of Pleckstrin homology domain-containing family F member 2-like protein vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
plekhf21.866e-5945.12pleckstrin homology domain containing, family F (w... [more]
plekhf21.866e-5945.12pleckstrin homology domain containing, family F (w... [more]
plekhf11.039e-3936.06pleckstrin homology domain containing, family F (w... [more]
plekhf11.039e-3936.06pleckstrin homology domain containing, family F (w... [more]
fgd62.608e-2934.30FYVE, RhoGEF and PH domain containing 6 [Source:ZF... [more]
back to top
BLAST of Pleckstrin homology domain-containing family F member 2-like protein vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5
Match NameE-valueIdentityDescription
eif4g36.360e-6144.13eukaryotic translation initiation factor 4 gamma, ... [more]
plekhf12.604e-5241.83pleckstrin homology and FYVE domain containing 1 [... [more]
mc3r1.752e-2729.67melanocortin 3 receptor [Source:Xenbase;Acc:XB-GEN... [more]
FGD47.887e-2030.32FYVE, RhoGEF and PH domain containing 4 [Source:NC... [more]
FGD41.590e-1730.10FYVE, RhoGEF and PH domain containing 4 [Source:NC... [more]
back to top
BLAST of Pleckstrin homology domain-containing family F member 2-like protein vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Plekhf21.082e-6045.28pleckstrin homology domain containing, family F (w... [more]
Plekhf23.841e-5544.67pleckstrin homology domain containing, family F (w... [more]
Plekhf13.902e-5542.59pleckstrin homology domain containing, family F (w... [more]
Fgd61.320e-2729.90FYVE, RhoGEF and PH domain containing 6 [Source:MG... [more]
Fgd45.144e-2027.00FYVE, RhoGEF and PH domain containing 4 [Source:MG... [more]
back to top
BLAST of Pleckstrin homology domain-containing family F member 2-like protein vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|O76902|PKHF1_DROME3.047e-6043.46Pleckstrin homology domain-containing family F mem... [more]
sp|Q5ZLY5|PKHF2_CHICK5.774e-6044.81Pleckstrin homology domain-containing family F mem... [more]
sp|Q91WB4|PKHF2_MOUSE7.567e-6045.28Pleckstrin homology domain-containing family F mem... [more]
sp|Q9H8W4|PKHF2_HUMAN1.579e-5944.81Pleckstrin homology domain-containing family F mem... [more]
sp|Q7ZUV1|PKHF2_DANRE1.409e-5845.12Pleckstrin homology domain-containing family F mem... [more]
back to top
BLAST of Pleckstrin homology domain-containing family F member 2-like protein vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
A0A443RKS46.036e-6044.60Pleckstrin domain-containing family F member 2-lik... [more]
M4AYP16.417e-6046.51Pleckstrin homology domain containing, family F (w... [more]
A0A139WEK47.080e-6045.33Pleckstrin homology domain-containing family F mem... [more]
A0A3B5L4I88.322e-6046.51Pleckstrin homology domain containing, family F (w... [more]
A0A3Q2G3D48.490e-6046.51Pleckstrin homology domain containing, family F (w... [more]
back to top
BLAST of Pleckstrin homology domain-containing family F member 2-like protein vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
plekhf23.549e-6045.12pleckstrin homology and FYVE domain containing 2 [... [more]
PLEKHF11.820e-4136.54pleckstrin homology and FYVE domain containing 1 [... [more]
fgd61.238e-2933.82FYVE, RhoGEF and PH domain containing 6 [Source:NC... [more]
ENSAMXT00000014177.23.132e-2631.67FYVE, RhoGEF and PH domain-containing protein 6-li... [more]
fgd5a2.926e-2231.47FYVE, RhoGEF and PH domain-containing protein 5-li... [more]
back to top
BLAST of Pleckstrin homology domain-containing family F member 2-like protein vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 5
Match NameE-valueIdentityDescription
plekhf22.587e-4938.94pleckstrin homology domain containing, family F (w... [more]
ENSPMAT00000005437.12.964e-1827.86pep scaffold:Pmarinus_7.0:GL486528:10206:16522:1 g... [more]
eea11.490e-1246.67early endosome antigen 1 [Source:ZFIN;Acc:ZDB-GENE... [more]
ENSPMAT00000001934.17.513e-1240.85pep scaffold:Pmarinus_7.0:GL488632:1056:3278:1 gen... [more]
fgd12.376e-1126.11FYVE, RhoGEF and PH domain containing 1 [Source:ZF... [more]
back to top
BLAST of Pleckstrin homology domain-containing family F member 2-like protein vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 2
Match NameE-valueIdentityDescription
VPS271.450e-940.91Endosomal protein that forms a complex with Hse1p;... [more]
PIB18.083e-743.90RING-type ubiquitin ligase of the endosomal and va... [more]
back to top
BLAST of Pleckstrin homology domain-containing family F member 2-like protein vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 5
Match NameE-valueIdentityDescription
EDO385016.751e-6345.62Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO482322.233e-2833.33Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO448642.473e-1238.82Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO490991.759e-1056.52Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO495333.617e-1043.33Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
back to top
BLAST of Pleckstrin homology domain-containing family F member 2-like protein vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5
Match NameE-valueIdentityDescription
plekhf21.868e-6144.93pleckstrin homology and FYVE domain containing 2 [... [more]
ENSORLT00000040317.15.430e-3938.76pleckstrin homology domain-containing family F mem... [more]
ENSORLT00000018711.28.708e-3938.76pleckstrin homology domain-containing family F mem... [more]
FGD63.685e-3133.00FYVE, RhoGEF and PH domain-containing protein 6 [S... [more]
FGD63.686e-3133.00FYVE, RhoGEF and PH domain-containing protein 6 [S... [more]
back to top
BLAST of Pleckstrin homology domain-containing family F member 2-like protein vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5
Match NameE-valueIdentityDescription
SMESG000038764.16.544e-6247.83SMESG000038764.1[more]
SMESG000028452.11.358e-5945.25SMESG000028452.1[more]
SMESG000038764.14.431e-5847.96SMESG000038764.1[more]
SMESG000066383.11.064e-1035.80SMESG000066383.1[more]
SMESG000066383.11.204e-1035.80SMESG000066383.1[more]
back to top
Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30013141 ID=SMED30013141|Name=Pleckstrin homology domain-containing family F member 2-like protein|organism=Schmidtea mediterranea sexual|type=transcript|length=894bp
CATAACGGGGTTTTGATTGGTTGATTGAAATAAATTTAACATTTATTACT
GTGAAAATTGTTCAAATCTGTTTGATACTTTTTATCGCTGAACTCTCATC
AGATGGAAGCTAATAAAGAAAGAATCAAGGAAATAGATTCACTGTTTGGG
AATTCATATCCACCTCTTTATCAAGAAAAACGAACATTGATTGGTGAAGG
AACACTTGTTAAAGTCTGTAGAAAACAATCGAAAAAGAGGCAATTTTTTC
TCTTCTCCGATATATTAGTTTATTGCAAATATATTTGGAAAGGAACAAAA
TTGACAAGTCAACATGTTTTCCCATTATCTGTCATGGAAATTGAAGAAGT
ACCTAATAATGACATTCTAGAACACGGATTTATTATTAAAAGTCCGAAAA
AATCATTCATCGTGTATGCAGCAACTAGTGACGAAAGAGAACAATGGATG
CGGCACATAAGGAACTGTATGTTGCAATGCGGTGGAGAAAGTACATACAT
TTGTGTGTATAATGCGTGTTCAAAAGCAGATTCTTTGAAAAGTCCAGTCT
GGGTCCCCGACGATGAAACTGAAACCTGTATGGTATGCCGAGTGACAAAT
TTCAGTTTGATAACTCGTAAACACCATTGTCGAAAATGTGGTAAGGTTGT
TTGTTTGAAGTGCTCCCAGAAGCGTTTTCTCATCCCAGAAATATCATGTG
ATACAGTTAGGGTGTGTGATACGTGCTATTTTGTCTTATCCCAGATACAA
TAAATGATATAATCAGATCATAACTCTTCTCTCTGAACAATGCTCAAATT
TATACAAAATAAACTTTATTTATTGGAATTTATTTATATGATTTAGTTTC
GCAAATATTTTTGATAAAAAACTCAACATTTAATTCACAATTTA
back to top

protein sequence of SMED30013141-orf-1

>SMED30013141-orf-1 ID=SMED30013141-orf-1|Name=SMED30013141-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=217bp
MEANKERIKEIDSLFGNSYPPLYQEKRTLIGEGTLVKVCRKQSKKRQFFL
FSDILVYCKYIWKGTKLTSQHVFPLSVMEIEEVPNNDILEHGFIIKSPKK
SFIVYAATSDEREQWMRHIRNCMLQCGGESTYICVYNACSKADSLKSPVW
VPDDETETCMVCRVTNFSLITRKHHCRKCGKVVCLKCSQKRFLIPEISCD
TVRVCDTCYFVLSQIQ*
back to top
Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000016pharynx
PLANA:0000020protonephridia
PLANA:0000034epidermis
PLANA:0002032epidermal cell
PLANA:0003116parenchymal cell
Vocabulary: INTERPRO
TermDefinition
IPR000306Znf_FYVE
IPR001849PH_domain
IPR011993PH-like_dom_sf
IPR013083Znf_RING/FYVE/PHD
IPR017455Znf_FYVE-rel
IPR011011Znf_FYVE_PHD
Vocabulary: molecular function
TermDefinition
GO:0046872metal ion binding
GO:0035091phosphatidylinositol binding
Vocabulary: cellular component
TermDefinition
GO:0005737cytoplasm
GO:0005768endosome
GO:0005769early endosome
GO:0005770late endosome
GO:0005886plasma membrane
GO:0005938cell cortex
GO:0010008endosome membrane
GO:0016020membrane
GO:0016324apical plasma membrane
Vocabulary: biological process
TermDefinition
GO:0006897endocytosis
GO:0007032endosome organization
GO:0008333endosome to lysosome transport
GO:0048812neuron projection morphogenesis
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR001849Pleckstrin homology domainSMARTSM00233PH_updatecoord: 29..126
e-value: 1.6E-15
score: 67.6
IPR001849Pleckstrin homology domainPFAMPF00169PHcoord: 33..123
e-value: 4.9E-11
score: 43.1
IPR001849Pleckstrin homology domainPROSITEPS50003PH_DOMAINcoord: 28..124
score: 12.757
IPR000306FYVE zinc fingerSMARTSM00064fyve_4coord: 145..214
e-value: 7.8E-22
score: 88.5
IPR000306FYVE zinc fingerPFAMPF01363FYVEcoord: 149..213
e-value: 7.8E-18
score: 64.4
IPR011993PH-like domain superfamilyGENE3DG3DSA:2.30.29.30coord: 21..121
e-value: 2.6E-26
score: 94.0
IPR013083Zinc finger, RING/FYVE/PHD-typeGENE3DG3DSA:3.30.40.10coord: 138..216
e-value: 1.9E-21
score: 77.5
NoneNo IPR availablePANTHERPTHR46280FAMILY NOT NAMEDcoord: 1..213
NoneNo IPR availableSUPERFAMILYSSF50729PH domain-likecoord: 4..128
IPR017455Zinc finger, FYVE-relatedPROSITEPS50178ZF_FYVEcoord: 153..213
score: 12.179
IPR011011Zinc finger, FYVE/PHD-typeSUPERFAMILYSSF57903FYVE/PHD zinc fingercoord: 148..214