Septin-2
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Overview
Neoblast Clusters
Zeng et. al., 2018▻ Overview▻ Neoblast Population▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Overview
Single cell RNA-seq of pluripotent neoblasts and its early progeniesWe isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)Explore this single cell expression dataset with our NB Cluster Shiny App
Neoblast Population
Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Embryonic Expression
Davies et. al., 2017
Hover the mouse over a column in the graph to view average RPKM values per sample. Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult. back to top Anatomical Expression
PAGE et. al., 2020SMED30013132 has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGEPAGE Curations: 6
Homology
BLAST of Septin-2 vs. Ensembl Human
Match: SEPTIN10 (septin 10 [Source:HGNC Symbol;Acc:HGNC:14349]) HSP 1 Score: 451.055 bits (1159), Expect = 2.727e-151 Identity = 237/404 (58.66%), Postives = 322/404 (79.70%), Query Frame = 1
Query: 97 TTEVVKGLANE-IRTLKINGHVGFDTLPYQLVNKAVNQGFSFNILCLGETGLGKSTLMETLFEQNFDFTPSTHDLPEVSLKVSNFDLKEGNVKLKLSIIESCGFGDQINKEDCVNPVISYIDGEFEKYLQEEMKIKRNLYNYHDTRVHVCLYFIAPTGHTMKSLDLVAMKKLESKVSIIPVIAKSDTITKSEMQKFKAKIMNEIQSNKINIYQFPTTDDTVRELNTQMNQLLPFAVVGSNDEAKMPNGKVSRVRQYPWGTVQIDNDNHCDFIRLREMLLRTNMDDLRERTHLVHYETYRKHRLIEMGFSD----NENMSLXXXXXXXXXXXXXXXXXXXXXIRQMFFMRVKEKENQLKESDKELLAKFESLKKSNAXXXXXXXXXXXXXXXDIGNFEKRKAIVE 1293
++EV + L E IR+L ++GHVGF++LP QLVN+++ QGF FNILC+GETG+GKSTL++TLF NF+ S+H P V LK ++L+E NV+LKL+I+ + GFGDQINKE+ P++ YID +FE YLQEE+KIKR+L+ YHD+R+HVCLYFI+PTGH++K+LDL+ MK L+SKV+IIPVIAK+DT++K+E+QKFK K+M+E+ SN + IYQFPT DDT+ ++N MN LPFAVVGS DE K+ N K+ + RQYPWG VQ++N+NHCDF++LREML+ TNM+DLRE+TH HYE YR+ +L EMGF+D N+ +S+QETY+ +R E ++KEEE++QMF RVKEKE LKE+++EL AKFE LK+ + EE+ KLEE+RR+LEE+I F K+KA E
Sbjct: 3 SSEVARHLKRENIRSLTMSGHVGFESLPDQLVNRSIQQGFCFNILCVGETGIGKSTLIDTLFNTNFEDYESSHFCPNVKLKAQTYELQESNVQLKLTIVNTVGFGDQINKEESYQPIVDYIDAQFEAYLQEELKIKRSLFTYHDSRIHVCLYFISPTGHSLKTLDLLTMKNLDSKVNIIPVIAKADTVSKTELQKFKIKLMSELVSNGVQIYQFPTDDDTIAKVNAAMNGQLPFAVVGSMDEVKVGN-KMVKARQYPWGVVQVENENHCDFVKLREMLICTNMEDLREQTHTRHYELYRRCKLEEMGFTDVGPENKPVSVQETYEAKRHEFHGERQRKEEEMKQMFVQRVKEKEAILKEAERELQAKFEHLKRLHQEERMKLEEKRRLLEEEIIAFSKKKATSE 405
BLAST of Septin-2 vs. Ensembl Human
Match: SEPTIN10 (septin 10 [Source:HGNC Symbol;Acc:HGNC:14349]) HSP 1 Score: 448.743 bits (1153), Expect = 4.130e-150 Identity = 233/392 (59.44%), Postives = 315/392 (80.36%), Query Frame = 1
Query: 130 IRTLKINGHVGFDTLPYQLVNKAVNQGFSFNILCLGETGLGKSTLMETLFEQNFDFTPSTHDLPEVSLKVSNFDLKEGNVKLKLSIIESCGFGDQINKEDCVNPVISYIDGEFEKYLQEEMKIKRNLYNYHDTRVHVCLYFIAPTGHTMKSLDLVAMKKLESKVSIIPVIAKSDTITKSEMQKFKAKIMNEIQSNKINIYQFPTTDDTVRELNTQMNQLLPFAVVGSNDEAKMPNGKVSRVRQYPWGTVQIDNDNHCDFIRLREMLLRTNMDDLRERTHLVHYETYRKHRLIEMGFSD----NENMSLXXXXXXXXXXXXXXXXXXXXXIRQMFFMRVKEKENQLKESDKELLAKFESLKKSNAXXXXXXXXXXXXXXXDIGNFEKRKAIVE 1293
IR+L ++GHVGF++LP QLVN+++ QGF FNILC+GETG+GKSTL++TLF NF+ S+H P V LK ++L+E NV+LKL+I+ + GFGDQINKE+ P++ YID +FE YLQEE+KIKR+L+ YHD+R+HVCLYFI+PTGH++K+LDL+ MK L+SKV+IIPVIAK+DT++K+E+QKFK K+M+E+ SN + IYQFPT DDT+ ++N MN LPFAVVGS DE K+ N K+ + RQYPWG VQ++N+NHCDF++LREML+ TNM+DLRE+TH HYE YR+ +L EMGF+D N+ +S+QETY+ +R E ++KEEE++QMF RVKEKE LKE+++EL AKFE LK+ + EE+ KLEE+RR+LEE+I F K+KA E
Sbjct: 38 IRSLTMSGHVGFESLPDQLVNRSIQQGFCFNILCVGETGIGKSTLIDTLFNTNFEDYESSHFCPNVKLKAQTYELQESNVQLKLTIVNTVGFGDQINKEESYQPIVDYIDAQFEAYLQEELKIKRSLFTYHDSRIHVCLYFISPTGHSLKTLDLLTMKNLDSKVNIIPVIAKADTVSKTELQKFKIKLMSELVSNGVQIYQFPTDDDTIAKVNAAMNGQLPFAVVGSMDEVKVGN-KMVKARQYPWGVVQVENENHCDFVKLREMLICTNMEDLREQTHTRHYELYRRCKLEEMGFTDVGPENKPVSVQETYEAKRHEFHGERQRKEEEMKQMFVQRVKEKEAILKEAERELQAKFEHLKRLHQEERMKLEEKRRLLEEEIIAFSKKKATSE 428
BLAST of Septin-2 vs. Ensembl Human
Match: SEPTIN10 (septin 10 [Source:HGNC Symbol;Acc:HGNC:14349]) HSP 1 Score: 448.358 bits (1152), Expect = 5.211e-150 Identity = 233/392 (59.44%), Postives = 315/392 (80.36%), Query Frame = 1
Query: 130 IRTLKINGHVGFDTLPYQLVNKAVNQGFSFNILCLGETGLGKSTLMETLFEQNFDFTPSTHDLPEVSLKVSNFDLKEGNVKLKLSIIESCGFGDQINKEDCVNPVISYIDGEFEKYLQEEMKIKRNLYNYHDTRVHVCLYFIAPTGHTMKSLDLVAMKKLESKVSIIPVIAKSDTITKSEMQKFKAKIMNEIQSNKINIYQFPTTDDTVRELNTQMNQLLPFAVVGSNDEAKMPNGKVSRVRQYPWGTVQIDNDNHCDFIRLREMLLRTNMDDLRERTHLVHYETYRKHRLIEMGFSD----NENMSLXXXXXXXXXXXXXXXXXXXXXIRQMFFMRVKEKENQLKESDKELLAKFESLKKSNAXXXXXXXXXXXXXXXDIGNFEKRKAIVE 1293
IR+L ++GHVGF++LP QLVN+++ QGF FNILC+GETG+GKSTL++TLF NF+ S+H P V LK ++L+E NV+LKL+I+ + GFGDQINKE+ P++ YID +FE YLQEE+KIKR+L+ YHD+R+HVCLYFI+PTGH++K+LDL+ MK L+SKV+IIPVIAK+DT++K+E+QKFK K+M+E+ SN + IYQFPT DDT+ ++N MN LPFAVVGS DE K+ N K+ + RQYPWG VQ++N+NHCDF++LREML+ TNM+DLRE+TH HYE YR+ +L EMGF+D N+ +S+QETY+ +R E ++KEEE++QMF RVKEKE LKE+++EL AKFE LK+ + EE+ KLEE+RR+LEE+I F K+KA E
Sbjct: 38 IRSLTMSGHVGFESLPDQLVNRSIQQGFCFNILCVGETGIGKSTLIDTLFNTNFEDYESSHFCPNVKLKAQTYELQESNVQLKLTIVNTVGFGDQINKEESYQPIVDYIDAQFEAYLQEELKIKRSLFTYHDSRIHVCLYFISPTGHSLKTLDLLTMKNLDSKVNIIPVIAKADTVSKTELQKFKIKLMSELVSNGVQIYQFPTDDDTIAKVNAAMNGQLPFAVVGSMDEVKVGN-KMVKARQYPWGVVQVENENHCDFVKLREMLICTNMEDLREQTHTRHYELYRRCKLEEMGFTDVGPENKPVSVQETYEAKRHEFHGERQRKEEEMKQMFVQRVKEKEAILKEAERELQAKFEHLKRLHQEERMKLEEKRRLLEEEIIAFSKKKATSE 428
BLAST of Septin-2 vs. Ensembl Human
Match: SEPTIN10 (septin 10 [Source:HGNC Symbol;Acc:HGNC:14349]) HSP 1 Score: 447.203 bits (1149), Expect = 3.487e-149 Identity = 233/392 (59.44%), Postives = 315/392 (80.36%), Query Frame = 1
Query: 130 IRTLKINGHVGFDTLPYQLVNKAVNQGFSFNILCLGETGLGKSTLMETLFEQNFDFTPSTHDLPEVSLKVSNFDLKEGNVKLKLSIIESCGFGDQINKEDCVNPVISYIDGEFEKYLQEEMKIKRNLYNYHDTRVHVCLYFIAPTGHTMKSLDLVAMKKLESKVSIIPVIAKSDTITKSEMQKFKAKIMNEIQSNKINIYQFPTTDDTVRELNTQMNQLLPFAVVGSNDEAKMPNGKVSRVRQYPWGTVQIDNDNHCDFIRLREMLLRTNMDDLRERTHLVHYETYRKHRLIEMGFSD----NENMSLXXXXXXXXXXXXXXXXXXXXXIRQMFFMRVKEKENQLKESDKELLAKFESLKKSNAXXXXXXXXXXXXXXXDIGNFEKRKAIVE 1293
IR+L ++GHVGF++LP QLVN+++ QGF FNILC+GETG+GKSTL++TLF NF+ S+H P V LK ++L+E NV+LKL+I+ + GFGDQINKE+ P++ YID +FE YLQEE+KIKR+L+ YHD+R+HVCLYFI+PTGH++K+LDL+ MK L+SKV+IIPVIAK+DT++K+E+QKFK K+M+E+ SN + IYQFPT DDT+ ++N MN LPFAVVGS DE K+ N K+ + RQYPWG VQ++N+NHCDF++LREML+ TNM+DLRE+TH HYE YR+ +L EMGF+D N+ +S+QETY+ +R E ++KEEE++QMF RVKEKE LKE+++EL AKFE LK+ + EE+ KLEE+RR+LEE+I F K+KA E
Sbjct: 23 IRSLTMSGHVGFESLPDQLVNRSIQQGFCFNILCVGETGIGKSTLIDTLFNTNFEDYESSHFCPNVKLKAQTYELQESNVQLKLTIVNTVGFGDQINKEESYQPIVDYIDAQFEAYLQEELKIKRSLFTYHDSRIHVCLYFISPTGHSLKTLDLLTMKNLDSKVNIIPVIAKADTVSKTELQKFKIKLMSELVSNGVQIYQFPTDDDTIAKVNAAMNGQLPFAVVGSMDEVKVGN-KMVKARQYPWGVVQVENENHCDFVKLREMLICTNMEDLREQTHTRHYELYRRCKLEEMGFTDVGPENKPVSVQETYEAKRHEFHGERQRKEEEMKQMFVQRVKEKEAILKEAERELQAKFEHLKRLHQEERMKLEEKRRLLEEEIIAFSKKKATSE 413
BLAST of Septin-2 vs. Ensembl Human
Match: SEPTIN10 (septin 10 [Source:HGNC Symbol;Acc:HGNC:14349]) HSP 1 Score: 447.973 bits (1151), Expect = 1.594e-148 Identity = 233/392 (59.44%), Postives = 315/392 (80.36%), Query Frame = 1
Query: 130 IRTLKINGHVGFDTLPYQLVNKAVNQGFSFNILCLGETGLGKSTLMETLFEQNFDFTPSTHDLPEVSLKVSNFDLKEGNVKLKLSIIESCGFGDQINKEDCVNPVISYIDGEFEKYLQEEMKIKRNLYNYHDTRVHVCLYFIAPTGHTMKSLDLVAMKKLESKVSIIPVIAKSDTITKSEMQKFKAKIMNEIQSNKINIYQFPTTDDTVRELNTQMNQLLPFAVVGSNDEAKMPNGKVSRVRQYPWGTVQIDNDNHCDFIRLREMLLRTNMDDLRERTHLVHYETYRKHRLIEMGFSD----NENMSLXXXXXXXXXXXXXXXXXXXXXIRQMFFMRVKEKENQLKESDKELLAKFESLKKSNAXXXXXXXXXXXXXXXDIGNFEKRKAIVE 1293
IR+L ++GHVGF++LP QLVN+++ QGF FNILC+GETG+GKSTL++TLF NF+ S+H P V LK ++L+E NV+LKL+I+ + GFGDQINKE+ P++ YID +FE YLQEE+KIKR+L+ YHD+R+HVCLYFI+PTGH++K+LDL+ MK L+SKV+IIPVIAK+DT++K+E+QKFK K+M+E+ SN + IYQFPT DDT+ ++N MN LPFAVVGS DE K+ N K+ + RQYPWG VQ++N+NHCDF++LREML+ TNM+DLRE+TH HYE YR+ +L EMGF+D N+ +S+QETY+ +R E ++KEEE++QMF RVKEKE LKE+++EL AKFE LK+ + EE+ KLEE+RR+LEE+I F K+KA E
Sbjct: 38 IRSLTMSGHVGFESLPDQLVNRSIQQGFCFNILCVGETGIGKSTLIDTLFNTNFEDYESSHFCPNVKLKAQTYELQESNVQLKLTIVNTVGFGDQINKEESYQPIVDYIDAQFEAYLQEELKIKRSLFTYHDSRIHVCLYFISPTGHSLKTLDLLTMKNLDSKVNIIPVIAKADTVSKTELQKFKIKLMSELVSNGVQIYQFPTDDDTIAKVNAAMNGQLPFAVVGSMDEVKVGN-KMVKARQYPWGVVQVENENHCDFVKLREMLICTNMEDLREQTHTRHYELYRRCKLEEMGFTDVGPENKPVSVQETYEAKRHEFHGERQRKEEEMKQMFVQRVKEKEAILKEAERELQAKFEHLKRLHQEERMKLEEKRRLLEEEIIAFSKKKATSE 428
BLAST of Septin-2 vs. Ensembl Celegans
Match: unc-61 (pep chromosome:WBcel235:V:14731095:14733877:-1 gene:WBGene00006795.1 transcript:Y50E8A.4c.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:unc-61) HSP 1 Score: 369.392 bits (947), Expect = 1.349e-119 Identity = 160/308 (51.95%), Postives = 232/308 (75.32%), Query Frame = 1
Query: 109 VKGLANEI-RTLKINGHVGFDTLPYQLVNKAVNQGFSFNILCLGETGLGKSTLMETLFEQNFDFTPSTHDLPEVSLKVSNFDLKEGNVKLKLSIIESCGFGDQINKEDCVNPVISYIDGEFEKYLQEEMKIKRNLYNYHDTRVHVCLYFIAPTGHTMKSLDLVAMKKLESKVSIIPVIAKSDTITKSEMQKFKAKIMNEIQSNKINIYQFPTTDDTVRELNTQMNQLLPFAVVGSNDEAKMPNGKVSRVRQYPWGTVQIDNDNHCDFIRLREMLLRTNMDDLRERTHLVHYETYRKHRLIEMGFSDNE 1029
+K L++ R +++NGHVGFD+LP+QLV KAV GF FN++C+GETG GK+TL+E+LF DF P H+L V L+ D+ EG +++KL ++E+ GFGDQ++K+ ++ Y++ +FE YLQEE+K +R L ++D+R+H CLYFI+PTGH +K+LDLV +++L +V++IPVIAKSDT K E+ +FKAKI++E++S KI+IY FPT D+TV N +MN+ +PFAVVGS D K NG++ R RQYPWG V+++N++HCDF++LRE LLRTN+D++R+RTH YE YR+ RL +M D E
Sbjct: 63 IKSLSDHTGRVMQLNGHVGFDSLPHQLVKKAVEAGFQFNLMCVGETGTGKTTLIESLFNMKLDFEPCNHELKTVELRTCTKDVAEGGIRVKLRLVETAGFGDQLDKDKSAKVIVDYLESQFETYLQEELKPRRMLQYFNDSRIHACLYFISPTGHGLKALDLVTLRELAKRVNVIPVIAKSDTTCKDELLRFKAKILSELKSQKIDIYTFPTDDETVSTTNKEMNKSVPFAVVGSIDFVKKENGQMVRARQYPWGIVEVENESHCDFVKLREALLRTNVDEMRQRTHESLYENYRRDRLRQMKIGDGE 370
BLAST of Septin-2 vs. Ensembl Celegans
Match: unc-61 (pep chromosome:WBcel235:V:14731095:14733877:-1 gene:WBGene00006795.1 transcript:Y50E8A.4b.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:unc-61) HSP 1 Score: 369.007 bits (946), Expect = 1.380e-119 Identity = 160/308 (51.95%), Postives = 232/308 (75.32%), Query Frame = 1
Query: 109 VKGLANEI-RTLKINGHVGFDTLPYQLVNKAVNQGFSFNILCLGETGLGKSTLMETLFEQNFDFTPSTHDLPEVSLKVSNFDLKEGNVKLKLSIIESCGFGDQINKEDCVNPVISYIDGEFEKYLQEEMKIKRNLYNYHDTRVHVCLYFIAPTGHTMKSLDLVAMKKLESKVSIIPVIAKSDTITKSEMQKFKAKIMNEIQSNKINIYQFPTTDDTVRELNTQMNQLLPFAVVGSNDEAKMPNGKVSRVRQYPWGTVQIDNDNHCDFIRLREMLLRTNMDDLRERTHLVHYETYRKHRLIEMGFSDNE 1029
+K L++ R +++NGHVGFD+LP+QLV KAV GF FN++C+GETG GK+TL+E+LF DF P H+L V L+ D+ EG +++KL ++E+ GFGDQ++K+ ++ Y++ +FE YLQEE+K +R L ++D+R+H CLYFI+PTGH +K+LDLV +++L +V++IPVIAKSDT K E+ +FKAKI++E++S KI+IY FPT D+TV N +MN+ +PFAVVGS D K NG++ R RQYPWG V+++N++HCDF++LRE LLRTN+D++R+RTH YE YR+ RL +M D E
Sbjct: 63 IKSLSDHTGRVMQLNGHVGFDSLPHQLVKKAVEAGFQFNLMCVGETGTGKTTLIESLFNMKLDFEPCNHELKTVELRTCTKDVAEGGIRVKLRLVETAGFGDQLDKDKSAKVIVDYLESQFETYLQEELKPRRMLQYFNDSRIHACLYFISPTGHGLKALDLVTLRELAKRVNVIPVIAKSDTTCKDELLRFKAKILSELKSQKIDIYTFPTDDETVSTTNKEMNKSVPFAVVGSIDFVKKENGQMVRARQYPWGIVEVENESHCDFVKLREALLRTNVDEMRQRTHESLYENYRRDRLRQMKIGDGE 370
BLAST of Septin-2 vs. Ensembl Celegans
Match: unc-61 (pep chromosome:WBcel235:V:14731136:14734237:-1 gene:WBGene00006795.1 transcript:Y50E8A.4a.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:unc-61) HSP 1 Score: 369.777 bits (948), Expect = 6.169e-119 Identity = 160/308 (51.95%), Postives = 232/308 (75.32%), Query Frame = 1
Query: 109 VKGLANEI-RTLKINGHVGFDTLPYQLVNKAVNQGFSFNILCLGETGLGKSTLMETLFEQNFDFTPSTHDLPEVSLKVSNFDLKEGNVKLKLSIIESCGFGDQINKEDCVNPVISYIDGEFEKYLQEEMKIKRNLYNYHDTRVHVCLYFIAPTGHTMKSLDLVAMKKLESKVSIIPVIAKSDTITKSEMQKFKAKIMNEIQSNKINIYQFPTTDDTVRELNTQMNQLLPFAVVGSNDEAKMPNGKVSRVRQYPWGTVQIDNDNHCDFIRLREMLLRTNMDDLRERTHLVHYETYRKHRLIEMGFSDNE 1029
+K L++ R +++NGHVGFD+LP+QLV KAV GF FN++C+GETG GK+TL+E+LF DF P H+L V L+ D+ EG +++KL ++E+ GFGDQ++K+ ++ Y++ +FE YLQEE+K +R L ++D+R+H CLYFI+PTGH +K+LDLV +++L +V++IPVIAKSDT K E+ +FKAKI++E++S KI+IY FPT D+TV N +MN+ +PFAVVGS D K NG++ R RQYPWG V+++N++HCDF++LRE LLRTN+D++R+RTH YE YR+ RL +M D E
Sbjct: 132 IKSLSDHTGRVMQLNGHVGFDSLPHQLVKKAVEAGFQFNLMCVGETGTGKTTLIESLFNMKLDFEPCNHELKTVELRTCTKDVAEGGIRVKLRLVETAGFGDQLDKDKSAKVIVDYLESQFETYLQEELKPRRMLQYFNDSRIHACLYFISPTGHGLKALDLVTLRELAKRVNVIPVIAKSDTTCKDELLRFKAKILSELKSQKIDIYTFPTDDETVSTTNKEMNKSVPFAVVGSIDFVKKENGQMVRARQYPWGIVEVENESHCDFVKLREALLRTNVDEMRQRTHESLYENYRRDRLRQMKIGDGE 439
BLAST of Septin-2 vs. Ensembl Celegans
Match: unc-59 (pep chromosome:WBcel235:I:13629227:13633494:1 gene:WBGene00006793.1 transcript:W09C5.2.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:unc-59) HSP 1 Score: 219.164 bits (557), Expect = 4.764e-63 Identity = 111/287 (38.68%), Postives = 179/287 (62.37%), Query Frame = 1
Query: 154 HVGFDTLPYQLVNKAVNQGFSFNILCLGETGLGKSTLMETLF-----EQNFDFTPSTHDLPE-VSLKVSNFDLKEGNVKLKLSIIESCGFGDQINKEDCVNPVISYIDGEFEKYLQEEMKIKRNLYNYHDTRVHVCLYFIAPTGHTMKSLDLVAMKKLESKVSIIPVIAKSDTITKSEMQKFKAKIMNEIQSNKINIYQFPTTDD--TVRELNTQMNQLLPFAVVGSNDEAKMPNGKVSRVRQYPWGTVQIDNDNHCDFIRLREMLLRTNMDDLRERTHLVHYETYR 990
+ GF P Q+ +AV GF F ++ +G +GLGKST + TLF N + TH P V ++ L E +V L L+++++ GFGD +N C P+++Y++ +F + EE +I R D VH+CLYFI P+GH +K +D+ MK L +V+I+PVI+K+D +T+ E+ +FK +I+ + ++ +I +Y+FP +D T + ++ + LPFA++GSN K +GK R R+YPWGTV+++N H DF+ LR+M++RTN+ D+ + T VHYE +R
Sbjct: 27 YWGFANFPNQVFRRAVKNGFDFTLMVVGRSGLGKSTFINTLFLAEINNLNEKESAPTHPHPSTVRVEEKLVKLVENSVSLNLTLVDTPGFGDAVNNSKCWEPIVNYVESKFFEQFCEETRIDRG-EKIVDKCVHLCLYFIEPSGHGLKPIDIELMKHLHGRVNIVPVISKADCLTRDELLRFKKQIVKDAETAEIKLYKFPELEDPYTDKVAIEKLRKALPFAIIGSN-MLKEKDGKKIRYREYPWGTVEVENMQHNDFLTLRDMIIRTNLIDMIDVTRNVHYENFR 311
BLAST of Septin-2 vs. Ensembl Fly
Match: Sep2 (gene:FBgn0014029 transcript:FBtr0083945) HSP 1 Score: 464.922 bits (1195), Expect = 2.827e-157 Identity = 244/404 (60.40%), Postives = 317/404 (78.47%), Query Frame = 1
Query: 130 IRTLKINGHVGFDTLPYQLVNKAVNQGFSFNILCLGETGLGKSTLMETLFEQNFDFTPSTHDLPEVSLKVSNFDLKEGNVKLKLSIIESCGFGDQINKEDCVNPVISYIDGEFEKYLQEEMKIKRNLYNYHDTRVHVCLYFIAPTGHTMKSLDLVAMKKLESKVSIIPVIAKSDTITKSEMQKFKAKIMNEIQSNKINIYQFPTTDDTVRELNTQMNQLLPFAVVGSNDEAKMPNGKVSRVRQYPWGTVQIDNDNHCDFIRLREMLLRTNMDDLRERTHLVHYETYRKHRLIEMGF----SDNENMSLXXXXXXXXXXXXXXXXXXXXXIRQMFFMRVKEKENQLKESDKELLAKFESLKKSNAXXXXXXXXXXXXXXXDIGNFEKRKAIVEQAKQGNTIKKKK 1329
+RTLK +GHVGFD+LP QLVNK+V GF FN++C+GETGLGKSTLM+TLF +F+ TPS H LP V LK ++L+E NV+LKL+I ++ G+GDQINK+D V+ YID +FE YLQEE+KIKR+L HD+R+H+CLYFI PTGH +KSLDLV MKKL+SKV+IIPVIAK+DTI+K E+Q+FKAKI+ E+ +N ++IYQFPT D+TV E NT MN +PFAVVGS + K+ N K+ R RQYPWGTVQ++N+ HCDF++LREML+RTNM+D+RE+TH HYE YR+ RL +MGF SDN+ +S Q+T++ +R EL+ KEEE+RQMF RVKEKE +LKES+K+L AKFE LK+ +AEEKRKLEE R+ LEED +F++RK + A T+ K K
Sbjct: 15 LRTLKQSGHVGFDSLPDQLVNKSVQNGFVFNVMCIGETGLGKSTLMDTLFNTSFESTPSPHTLPSVKLKAHTYELQESNVRLKLTICDTVGYGDQINKDDSFKAVVDYIDAQFENYLQEELKIKRSLVTCHDSRIHICLYFICPTGHGLKSLDLVCMKKLDSKVNIIPVIAKADTISKVELQRFKAKIIQELNANGVHIYQFPTDDETVAETNTSMNSHIPFAVVGSTEFIKVGN-KLIRARQYPWGTVQVENETHCDFVKLREMLIRTNMEDMREKTHTRHYELYRQKRLEQMGFSDVDSDNKPISFQQTFEAKRSNHLAELQSKEEEVRQMFVQRVKEKEAELKESEKDLHAKFEKLKRDHAEEKRKLEESRKALEEDYLDFQRRKQQLATAHHTLTLGKSK 417
BLAST of Septin-2 vs. Ensembl Fly
Match: Sep5 (gene:FBgn0026361 transcript:FBtr0088877) HSP 1 Score: 428.713 bits (1101), Expect = 3.692e-143 Identity = 219/387 (56.59%), Postives = 296/387 (76.49%), Query Frame = 1
Query: 133 RTLKINGHVGFDTLPYQLVNKAVNQGFSFNILCLGETGLGKSTLMETLFEQNFDFTPSTHDLPEVSLKVSNFDLKEGNVKLKLSIIESCGFGDQINKEDCVNPVISYIDGEFEKYLQEEMKIKRNLYNYHDTRVHVCLYFIAPTGHTMKSLDLVAMKKLESKVSIIPVIAKSDTITKSEMQKFKAKIMNEIQSNKINIYQFPTTDDTVRELNTQMNQLLPFAVVGSNDEAKMPNGKVSRVRQYPWGTVQIDNDNHCDFIRLREMLLRTNMDDLRERTHLVHYETYRKHRLIEMGF----SDNENMSLXXXXXXXXXXXXXXXXXXXXXIRQMFFMRVKEKENQLKESDKELLAKFESLKKSNAXXXXXXXXXXXXXXXDIGNFEKRK 1281
R L++ GHVGFDTLP QLVNK+V GFSFNILC+GET LGKSTLM+TLF +F TPS H+LP V LK + ++L+E NV+LKL++ ++ G+GDQ+NK D ++ Y+D +FE YLQEE+KI+R + + HD RVH CLYFI PTGH +K++DLV MK+L+++V+IIPVIAK+DTI+KSE+ FK +IM+E++ N ++IYQFP D+TV E N MN LPFAVVGS + K+ GK R RQYPWG V I+N+ HCDF++LREML+RTNM+DLRE+TH HYE +R+ RL +MGF S+N+ +S Q+T++ +R L+ KEEE+RQMF RVK+KEN+LK+++KEL KF+ LK+ + EEK +LEE RR LEED ++R+
Sbjct: 19 RLLQLGGHVGFDTLPDQLVNKSVQNGFSFNILCIGETALGKSTLMDTLFNTSFGSTPSPHNLPNVKLKANTYELQESNVRLKLTVCDTIGYGDQVNKADSYKALVEYVDSQFEAYLQEELKIQRAMASAHDGRVHACLYFICPTGHGLKAMDLVCMKQLDTRVNIIPVIAKADTISKSELSGFKERIMDELRRNNVSIYQFPMDDETVSETNAAMNGHLPFAVVGSTEFVKVA-GKQVRARQYPWGAVHIENEAHCDFVKLREMLIRTNMEDLREQTHTRHYELFRQRRLQQMGFVDVDSNNQPVSFQQTFESKRSDHLACLQAKEEEVRQMFVQRVKQKENELKDNEKELHTKFDRLKREHLEEKAQLEEARRQLEEDCQELQRRR 404
BLAST of Septin-2 vs. Ensembl Fly
Match: Sep5 (gene:FBgn0026361 transcript:FBtr0088876) HSP 1 Score: 428.713 bits (1101), Expect = 3.692e-143 Identity = 219/387 (56.59%), Postives = 296/387 (76.49%), Query Frame = 1
Query: 133 RTLKINGHVGFDTLPYQLVNKAVNQGFSFNILCLGETGLGKSTLMETLFEQNFDFTPSTHDLPEVSLKVSNFDLKEGNVKLKLSIIESCGFGDQINKEDCVNPVISYIDGEFEKYLQEEMKIKRNLYNYHDTRVHVCLYFIAPTGHTMKSLDLVAMKKLESKVSIIPVIAKSDTITKSEMQKFKAKIMNEIQSNKINIYQFPTTDDTVRELNTQMNQLLPFAVVGSNDEAKMPNGKVSRVRQYPWGTVQIDNDNHCDFIRLREMLLRTNMDDLRERTHLVHYETYRKHRLIEMGF----SDNENMSLXXXXXXXXXXXXXXXXXXXXXIRQMFFMRVKEKENQLKESDKELLAKFESLKKSNAXXXXXXXXXXXXXXXDIGNFEKRK 1281
R L++ GHVGFDTLP QLVNK+V GFSFNILC+GET LGKSTLM+TLF +F TPS H+LP V LK + ++L+E NV+LKL++ ++ G+GDQ+NK D ++ Y+D +FE YLQEE+KI+R + + HD RVH CLYFI PTGH +K++DLV MK+L+++V+IIPVIAK+DTI+KSE+ FK +IM+E++ N ++IYQFP D+TV E N MN LPFAVVGS + K+ GK R RQYPWG V I+N+ HCDF++LREML+RTNM+DLRE+TH HYE +R+ RL +MGF S+N+ +S Q+T++ +R L+ KEEE+RQMF RVK+KEN+LK+++KEL KF+ LK+ + EEK +LEE RR LEED ++R+
Sbjct: 19 RLLQLGGHVGFDTLPDQLVNKSVQNGFSFNILCIGETALGKSTLMDTLFNTSFGSTPSPHNLPNVKLKANTYELQESNVRLKLTVCDTIGYGDQVNKADSYKALVEYVDSQFEAYLQEELKIQRAMASAHDGRVHACLYFICPTGHGLKAMDLVCMKQLDTRVNIIPVIAKADTISKSELSGFKERIMDELRRNNVSIYQFPMDDETVSETNAAMNGHLPFAVVGSTEFVKVA-GKQVRARQYPWGAVHIENEAHCDFVKLREMLIRTNMEDLREQTHTRHYELFRQRRLQQMGFVDVDSNNQPVSFQQTFESKRSDHLACLQAKEEEVRQMFVQRVKQKENELKDNEKELHTKFDRLKREHLEEKAQLEEARRQLEEDCQELQRRR 404
BLAST of Septin-2 vs. Ensembl Fly
Match: Sep2 (gene:FBgn0014029 transcript:FBtr0334579) HSP 1 Score: 391.349 bits (1004), Expect = 1.343e-129 Identity = 211/359 (58.77%), Postives = 277/359 (77.16%), Query Frame = 1
Query: 265 METLFEQNFDFTPSTHDLPEVSLKVSNFDLKEGNVKLKLSIIESCGFGDQINKEDCVNPVISYIDGEFEKYLQEEMKIKRNLYNYHDTRVHVCLYFIAPTGHTMKSLDLVAMKKLESKVSIIPVIAKSDTITKSEMQKFKAKIMNEIQSNKINIYQFPTTDDTVRELNTQMNQLLPFAVVGSNDEAKMPNGKVSRVRQYPWGTVQIDNDNHCDFIRLREMLLRTNMDDLRERTHLVHYETYRKHRLIEMGF----SDNENMSLXXXXXXXXXXXXXXXXXXXXXIRQMFFMRVKEKENQLKESDKELLAKFESLKKSNAXXXXXXXXXXXXXXXDIGNFEKRKAIVEQAKQGNTIKKKK 1329
M+TLF +F+ TPS H LP V LK ++L+E NV+LKL+I ++ G+GDQINK+D V+ YID +FE YLQEE+KIKR+L HD+R+H+CLYFI PTGH +KSLDLV MKKL+SKV+IIPVIAK+DTI+K E+Q+FKAKI+ E+ +N ++IYQFPT D+TV E NT MN +PFAVVGS + K+ N K+ R RQYPWGTVQ++N+ HCDF++LREML+RTNM+D+RE+TH HYE YR+ RL +MGF SDN+ +S Q+T++ +R EL+ KEEE+RQMF RVKEKE +LKES+K+L AKFE LK+ +AEEKRKLEE R+ LEED +F++RK + A T+ K K
Sbjct: 1 MDTLFNTSFESTPSPHTLPSVKLKAHTYELQESNVRLKLTICDTVGYGDQINKDDSFKAVVDYIDAQFENYLQEELKIKRSLVTCHDSRIHICLYFICPTGHGLKSLDLVCMKKLDSKVNIIPVIAKADTISKVELQRFKAKIIQELNANGVHIYQFPTDDETVAETNTSMNSHIPFAVVGSTEFIKVGN-KLIRARQYPWGTVQVENETHCDFVKLREMLIRTNMEDMREKTHTRHYELYRQKRLEQMGFSDVDSDNKPISFQQTFEAKRSNHLAELQSKEEEVRQMFVQRVKEKEAELKESEKDLHAKFEKLKRDHAEEKRKLEESRKALEEDYLDFQRRKQQLATAHHTLTLGKSK 358
BLAST of Septin-2 vs. Ensembl Fly
Match: pnut (gene:FBgn0013726 transcript:FBtr0088792) HSP 1 Score: 278.485 bits (711), Expect = 5.713e-84 Identity = 148/369 (40.11%), Postives = 233/369 (63.14%), Query Frame = 1
Query: 133 RTLKINGHVGFDTLPYQLVNKAVNQGFSFNILCLGETGLGKSTLMETLFEQNFDFT-----PSTHDLPEVSLKVSNFDLKEGNVKLKLSIIESCGFGDQINKEDCVNPVISYIDGEFEKYLQEEMKIKRNLYNYHDTRVHVCLYFIAPTGHTMKSLDLVAMKKLESKVSIIPVIAKSDTITKSEMQKFKAKIMNEIQSNKINIYQFPTT-DDTVRELNTQMN--QLLPFAVVGSNDEAKMPNGKVSRVRQYPWGTVQIDNDNHCDFIRLREMLLRTNMDDLRERTHLVHYETYRKHRLIEMGFSDNE----NMSLXXXXXXXXXXXXXXXXXXXXXIRQMFFMRVKEKENQLKESDKELLAKFESLKKS 1203
+ ++I G+VGF LP Q+ KAV +GF F ++ +G +GLGKSTL+ ++F + PS V+++ + LKE V L L+++++ GFGD ++ +C P++ Y+D ++E+YL E ++ R + D+RVH CLYFIAP+GH + LD+ M+ L KV+++PVIAK+DT+T E+ FK +I+NEI +KI IY FP T +D E T N +PFAVVG+N + +GK R R+YPWG V+++N HCDFI LR M++RT++ DL++ T+ VHYE YR +L E+G D + N + ++ + +++K+ E E+ Q+F M+VKEK +L++S+ EL + E KK+
Sbjct: 115 KPMEIAGYVGFANLPNQVYRKAVKRGFEFTLMVVGASGLGKSTLINSMFLSDIYNAEQYPGPSLRKKKTVAVEATKVMLKENGVNLTLTVVDTPGFGDAVDNSNCWVPILEYVDSKYEEYLTAESRVYRKTIS--DSRVHCCLYFIAPSGHGLLPLDIACMQSLSDKVNLVPVIAKADTMTPDEVHLFKKQILNEIAQHKIKIYDFPATLEDAAEEAKTTQNLRSRVPFAVVGANTIIEQ-DGKKVRGRRYPWGLVEVENLTHCDFIALRNMVIRTHLQDLKDVTNNVHYENYRCRKLSELGLVDGKARLSNKNPLTQMEEEKREHEQKMKKMEAEMEQVFDMKVKEKMQKLRDSELELARRHEERKKA 480
BLAST of Septin-2 vs. Ensembl Zebrafish
Match: sept8b (septin 8b [Source:NCBI gene;Acc:571702]) HSP 1 Score: 449.129 bits (1154), Expect = 6.301e-151 Identity = 237/416 (56.97%), Postives = 320/416 (76.92%), Query Frame = 1
Query: 97 TTEVVKGLANEIRTLKINGHVGFDTLPYQLVNKAVNQGFSFNILCLGETGLGKSTLMETLFEQNFDFTPSTHDLPEVSLKVSNFDLKEGNVKLKLSIIESCGFGDQINKEDCVNPVISYIDGEFEKYLQEEMKIKRNLYNYHDTRVHVCLYFIAPTGHTMKSLDLVAMKKLESKVSIIPVIAKSDTITKSEMQKFKAKIMNEIQSNKINIYQFPTTDDTVRELNTQMNQLLPFAVVGSNDEAKMPNGKVSRVRQYPWGTVQIDNDNHCDFIRLREMLLRTNMDDLRERTHLVHYETYRKHRLIEMGF----SDNENMSLXXXXXXXXXXXXXXXXXXXXXIRQMFFMRVKEKENQLKESDKELLAKFESLKKSNAXXXXXXXXXXXXXXXDIGNFEKRKAIVE--QAKQGNTIKKK 1326
TEV E+R+L ++GHVGFD+LP QLV+K+V+QGFSFNILC+GETG+GKSTLM TLF F+ ++H V L+ + L+E NV L+L+I+++ GFGDQ+NKE+ P++ YID +FE +L+EE+KIKR+LYNYHD+R+H+CLYFIAP+GH++KSLDLV MKKL+SKV+IIP+IAK+DT++KSE+QKFK KIM+E+ SN + IYQFPT D+ V E+N+ MN LPFAV+GS++E K+ N K+ R RQYPWG VQ++N++HCDF++LREML+R NM DLRE+TH HYE YR+ +L EMGF +D+E SLQETY +R EL+ KEE++RQMF +VKE E +LKE ++EL +FE LK+++ EEKR LEE RR EE++ F +RK E Q+ QG+T KK
Sbjct: 3 ATEVNTYPTEEMRSLSLSGHVGFDSLPDQLVSKSVSQGFSFNILCVGETGIGKSTLMNTLFNTTFENEEASHFHNGVHLRPRTYSLQESNVDLQLTIVDTVGFGDQVNKEESYKPIVDYIDAQFENFLEEELKIKRSLYNYHDSRIHICLYFIAPSGHSLKSLDLVTMKKLDSKVNIIPIIAKADTVSKSELQKFKIKIMSELVSNGVQIYQFPTDDEAVAEINSSMNAHLPFAVIGSSEEVKIGN-KMVRARQYPWGVVQVENESHCDFVKLREMLIRVNMLDLREQTHARHYELYRRCKLEEMGFKDTDADSEPFSLQETYVAKRREFIGELQMKEEQMRQMFVNKVKETEAELKEKERELHERFEMLKRTHQEEKRSLEEMRRDFEEEMNTFNRRKVAAETLQSLQGSTGLKK 417
BLAST of Septin-2 vs. Ensembl Zebrafish
Match: sept10 (septin 10 [Source:ZFIN;Acc:ZDB-GENE-050417-3]) HSP 1 Score: 446.817 bits (1148), Expect = 6.837e-150 Identity = 236/412 (57.28%), Postives = 321/412 (77.91%), Query Frame = 1
Query: 97 TTEVVKGLANEIRTLKINGHVGFDTLPYQLVNKAVNQGFSFNILCLGETGLGKSTLMETLFEQNFDFTPSTHDLPEVSLKVSNFDLKEGNVKLKLSIIESCGFGDQINKEDCVNPVISYIDGEFEKYLQEEMKIKRNLYNYHDTRVHVCLYFIAPTGHTMKSLDLVAMKKLESKVSIIPVIAKSDTITKSEMQKFKAKIMNEIQSNKINIYQFPTTDDTVRELNTQMNQLLPFAVVGSNDEAKMPNGKVSRVRQYPWGTVQIDNDNHCDFIRLREMLLRTNMDDLRERTHLVHYETYRKHRLIEMGFSDNE----NMSLXXXXXXXXXXXXXXXXXXXXXIRQMFFMRVKEKENQLKESDKELLAKFESLKKSNAXXXXXXXXXXXXXXXDIGNFEKRKAIVE--QAKQGNT 1314
+++V++ R L ++GHVGFD+LP QLVNK+ +QGF FNILC+GETG+GKSTLM+TLF NF+ S+H P+V L+ +DL+E NV+LKL+++ + GFGDQ+NK++ ++ YID +FE YLQEE+KIKR+L+NYHD+R+H CLYFIAP+GH++KSLDLV MKKL+SKV+IIPVIAK+DTI+KSE+ KFK KIM+E+ SN + IYQFP D+TV ++NT MN LPFAVVGS +E + N K+ + RQYPWG VQ++N+NHCDF++LREML+ NM+DLRE+TH HYE YR+ +L EMGF D + +SLQ+TY+ +R+ EL+++EEE+RQ F RVKEKE +LK++++EL KFE LK+ +A+EK KLEE+RR LEE++ F KRKA E QA+ NT
Sbjct: 3 SSDVLRQPDKNARPLALSGHVGFDSLPDQLVNKSTSQGFCFNILCIGETGIGKSTLMDTLFNTNFENFESSHFEPKVKLRAQTYDLQESNVRLKLTVVNTVGFGDQMNKQESYQHIVDYIDTQFESYLQEELKIKRSLHNYHDSRIHACLYFIAPSGHSLKSLDLVTMKKLDSKVNIIPVIAKADTISKSELHKFKIKIMSELVSNGVQIYQFPIDDETVAKINTAMNGHLPFAVVGSTEEVNIGN-KMVKARQYPWGVVQVENENHCDFVKLREMLICVNMEDLREQTHTRHYELYRRCKLEEMGFKDTDPECKPVSLQQTYEAKRQEFLGELQRREEEMRQTFVQRVKEKEAELKDAERELQGKFEQLKRLHADEKSKLEEKRRSLEEEMSVFSKRKAATELLQAQSFNT 413
BLAST of Septin-2 vs. Ensembl Zebrafish
Match: sept8a (septin 8a [Source:NCBI gene;Acc:321590]) HSP 1 Score: 439.884 bits (1130), Expect = 2.039e-147 Identity = 237/405 (58.52%), Postives = 311/405 (76.79%), Query Frame = 1
Query: 127 EIRTLKINGHVGFDTLPYQLVNKAVNQGFSFNILCLGETGLGKSTLMETLFEQNFDFTPSTHDLPEVSLKVSNFDLKEGNVKLKLSIIESCGFGDQINKEDCVNPVISYIDGEFEKYLQEEMKIKRNLYNYHDTRVHVCLYFIAPTGHTMKSLDLVAMKKLESKVSIIPVIAKSDTITKSEMQKFKAKIMNEIQSNKINIYQFPTTDDTVRELNTQMNQLLPFAVVGSNDEAKMPNGKVSRVRQYPWGTVQIDNDNHCDFIRLREMLLRTNMDDLRERTHLVHYETYRKHRLIEMGF----SDNENMSLXXXXXXXXXXXXXXXXXXXXXIRQMFFMRVKEKENQLKESDKELLAKFESLKKSNAXXXXXXXXXXXXXXXDIGNFEKRKAIVEQAKQGNTIKKKK 1329
E R L + GHVGFD+LP QLV+K+V QGF FNILC+GETG+GKSTLM TLF F+ ++H V L+ +DL+E NV LKL+I+++ GFGDQINKE+ P++ YID +FE YLQEE+KIKR+L+NYHDTR+H+CLYFI+PTGH++KSLDLV MKKL+SKV+IIP+IAK+DTI+KSE+ KFK KIM+E+ SN + IYQFPT D+ V E+N+ MN LPFAVVGS +E K+ N K R RQYPWG VQ++N++HCDF++LREML+R NM+DLRE+TH HYE YR+ +L EMGF D++ SLQETY+ +R+ +L++KEEE+RQMF +VKE E +LKE ++EL KFE LK+ + EEKRK+EE+RR LEE++ F +RK E +KK K
Sbjct: 13 EKRNLSLGGHVGFDSLPDQLVSKSVTQGFCFNILCVGETGIGKSTLMNTLFNTMFENEEASHYQNGVYLRPRTYDLQESNVHLKLTIVDTVGFGDQINKEESYKPIVDYIDTQFENYLQEELKIKRSLFNYHDTRIHICLYFISPTGHSLKSLDLVTMKKLDSKVNIIPIIAKADTISKSELHKFKIKIMSELVSNGVQIYQFPTDDEAVTEINSSMNAHLPFAVVGSVEEVKVGN-KTVRARQYPWGVVQVENESHCDFVKLREMLIRVNMEDLREQTHARHYELYRRCKLEEMGFKDTDPDSQPFSLQETYEAKRKEFLGDLQKKEEEMRQMFVNKVKETEAELKEKERELHEKFEQLKRMHQEEKRKVEEKRRELEEEMNAFNRRKVAAETLSLSQPLKKDK 416
BLAST of Septin-2 vs. Ensembl Zebrafish
Match: sept6 (septin 6 [Source:ZFIN;Acc:ZDB-GENE-030131-1414]) HSP 1 Score: 433.335 bits (1113), Expect = 1.280e-144 Identity = 234/403 (58.06%), Postives = 315/403 (78.16%), Query Frame = 1
Query: 97 TTEVVKGLANEIRTLKINGHVGFDTLPYQLVNKAVNQGFSFNILCLGETGLGKSTLMETLFEQNFDFTPSTHDLPEVSLKVSNFDLKEGNVKLKLSIIESCGFGDQINKEDCVNPVISYIDGEFEKYLQEEMKIKRNLYNYHDTRVHVCLYFIAPTGHTMKSLDLVAMKKLESKVSIIPVIAKSDTITKSEMQKFKAKIMNEIQSNKINIYQFPTTDDTVRELNTQMNQLLPFAVVGSNDEAKMPNGKVSRVRQYPWGTVQIDNDNHCDFIRLREMLLRTNMDDLRERTHLVHYETYRKHRLIEMGF----SDNENMSLXXXXXXXXXXXXXXXXXXXXXIRQMFFMRVKEKENQLKESDKELLAKFESLKKSNAXXXXXXXXXXXXXXXDIGNFEKRKAIVE 1293
TE+ + R + ++GHVGFD++P QLVNK+VN GF FNILC+GETGLGKSTLM+TLF F+ P+ H+ P V LK + ++L+E NV+LKL+++ + GFGDQINKED ++ +ID +FE YLQEE+KIKR L++YHDTR+H CLYFIAPTGH++KSLDLV MKKL+SKV+IIP+IAKSD I+KSE+ KFK KI +E+ SN + IYQFPT D+TV E+N+ MN LPFAVVGS +E K+ N K+ R RQYPWGTVQ++N+NHCDF++LREML+R NM+DLRE+TH HYE YR+ +L EMGF D++ SLQETY+ +R EL++KEEE+RQMF RVKEKE +LKE++KEL KF+ LKK + +EK+KLE++++ L++++ F+++K E
Sbjct: 8 ATEIARQAGEGARAVPLSGHVGFDSMPDQLVNKSVNHGFCFNILCVGETGLGKSTLMDTLFNTKFEGEPTQHNQPGVQLKSNTYELQESNVRLKLTVVNTVGFGDQINKEDSYKSIVEFIDAQFEAYLQEELKIKRTLHSYHDTRIHACLYFIAPTGHSLKSLDLVTMKKLDSKVNIIPIIAKSDAISKSELAKFKIKITSELVSNGVQIYQFPTDDETVAEINSTMNGHLPFAVVGSTEEVKIGN-KMVRARQYPWGTVQVENENHCDFVKLREMLIRVNMEDLREQTHTRHYELYRRCKLEEMGFKDTDPDSKPFSLQETYEAKRNEFMGELQKKEEEMRQMFVQRVKEKEAELKEAEKELHEKFDRLKKLHQDEKKKLEDKKKSLDDELNGFKQKKTAAE 409
BLAST of Septin-2 vs. Ensembl Zebrafish
Match: sept6 (septin 6 [Source:ZFIN;Acc:ZDB-GENE-030131-1414]) HSP 1 Score: 433.335 bits (1113), Expect = 1.308e-144 Identity = 234/403 (58.06%), Postives = 314/403 (77.92%), Query Frame = 1
Query: 97 TTEVVKGLANEIRTLKINGHVGFDTLPYQLVNKAVNQGFSFNILCLGETGLGKSTLMETLFEQNFDFTPSTHDLPEVSLKVSNFDLKEGNVKLKLSIIESCGFGDQINKEDCVNPVISYIDGEFEKYLQEEMKIKRNLYNYHDTRVHVCLYFIAPTGHTMKSLDLVAMKKLESKVSIIPVIAKSDTITKSEMQKFKAKIMNEIQSNKINIYQFPTTDDTVRELNTQMNQLLPFAVVGSNDEAKMPNGKVSRVRQYPWGTVQIDNDNHCDFIRLREMLLRTNMDDLRERTHLVHYETYRKHRLIEMGFSDNE----NMSLXXXXXXXXXXXXXXXXXXXXXIRQMFFMRVKEKENQLKESDKELLAKFESLKKSNAXXXXXXXXXXXXXXXDIGNFEKRKAIVE 1293
TE+ + R + ++GHVGFD++P QLVNK+VN GF FNILC+GETGLGKSTLM+TLF F+ P+ H+ P V LK + ++L+E NV+LKL+++ + GFGDQINKED ++ +ID +FE YLQEE+KIKR L++YHDTR+H CLYFIAPTGH++KSLDLV MKKL+SKV+IIP+IAKSD I+KSE+ KFK KI +E+ SN + IYQFPT D+TV E+N+ MN LPFAVVGS +E K+ N K+ R RQYPWGTVQ++N+NHCDF++LREML+R NM+DLRE+TH HYE YR+ +L EMGF D + SLQETY+ +R EL++KEEE+RQMF RVKEKE +LKE++KEL KF+ LKK + +EK+KLE++++ L++++ F+++K E
Sbjct: 8 ATEIARQAGEGARAVPLSGHVGFDSMPDQLVNKSVNHGFCFNILCVGETGLGKSTLMDTLFNTKFEGEPTQHNQPGVQLKSNTYELQESNVRLKLTVVNTVGFGDQINKEDSYKSIVEFIDAQFEAYLQEELKIKRTLHSYHDTRIHACLYFIAPTGHSLKSLDLVTMKKLDSKVNIIPIIAKSDAISKSELAKFKIKITSELVSNGVQIYQFPTDDETVAEINSTMNGHLPFAVVGSTEEVKIGN-KMVRARQYPWGTVQVENENHCDFVKLREMLIRVNMEDLREQTHTRHYELYRRCKLEEMGFKDTDPDSKPFSLQETYEAKRNEFMGELQKKEEEMRQMFVQRVKEKEAELKEAEKELHEKFDRLKKLHQDEKKKLEDKKKSLDDELNGFKQKKTAAE 409
BLAST of Septin-2 vs. Ensembl Xenopus
Match: rag1 (recombination activating gene 1 [Source:Xenbase;Acc:XB-GENE-6087118]) HSP 1 Score: 445.277 bits (1144), Expect = 3.573e-149 Identity = 241/402 (59.95%), Postives = 327/402 (81.34%), Query Frame = 1
Query: 94 MTTEVVKGL-ANEIRTLKINGHVGFDTLPYQLVNKAVNQGFSFNILCLGETGLGKSTLMETLFEQNFDFTPSTHDLPEVSLKVSNFDLKEGNVKLKLSIIESCGFGDQINKEDCVNPVISYIDGEFEKYLQEEMKIKRNLYNYHDTRVHVCLYFIAPTGHTMKSLDLVAMKKLESKVSIIPVIAKSDTITKSEMQKFKAKIMNEIQSNKINIYQFPTTDDTVRELNTQMNQLLPFAVVGSNDEAKMPNGKVSRVRQYPWGTVQIDNDNHCDFIRLREMLLRTNMDDLRERTHLVHYETYRKHRLIEMGF----SDNENMSLXXXXXXXXXXXXXXXXXXXXXIRQMFFMRVKEKENQLKESDKELLAKFESLKKSNAXXXXXXXXXXXXXXXDIGNFEKRKA 1284
++ VKGL +++IRTL ++GHVGFD+LP QLVNK+ +QGF FNILC+GETG+GKSTLM+T+F F+ P +H P V LK +++L+E NV+LKL+I+++ GFGDQINKE+ P++ YID +FE YLQEE+KIKR+LYNYHDTR+H CLYFIAPTGH++KSLDLV MKKL+SKV+IIP+IAK+DTI K+E+ KFK+KIMNE+ SN + IYQFPT ++TV E+N M+ LPFAVVGS +E K+ N K+++ RQYPWG VQ++N+NHCDF++LREML+R NM+DLRE+TH HYE YR+ +L EMGF D++ SLQETY+ +R EL++KEEE+RQMF MRVKEKE +LKE++KEL KF+ LK+++ EEK+KLE++++ +EE++ F+K+KA
Sbjct: 7 LSQHSVKGLPSDDIRTLSMSGHVGFDSLPDQLVNKSTSQGFCFNILCVGETGIGKSTLMDTIFNTKFENEPVSHSEPAVQLKARSYELQESNVRLKLTIVDTVGFGDQINKEESYRPIVEYIDAQFEAYLQEELKIKRSLYNYHDTRIHACLYFIAPTGHSLKSLDLVTMKKLDSKVNIIPIIAKADTIAKNELHKFKSKIMNELVSNGVQIYQFPTDEETVAEINATMSVHLPFAVVGSTEEVKIGN-KMAKARQYPWGIVQVENENHCDFVKLREMLIRVNMEDLREQTHARHYELYRRCKLEEMGFKDTAPDSKPFSLQETYEAKRNEFLGELQKKEEEMRQMFVMRVKEKEAELKEAEKELHEKFDLLKRTHQEEKKKLEDKKKEIEEEVNMFQKKKA 407
BLAST of Septin-2 vs. Ensembl Xenopus
Match: rag1 (recombination activating gene 1 [Source:Xenbase;Acc:XB-GENE-6087118]) HSP 1 Score: 443.736 bits (1140), Expect = 1.296e-148 Identity = 238/399 (59.65%), Postives = 326/399 (81.70%), Query Frame = 1
Query: 100 TEVVKGLANEIRTLKINGHVGFDTLPYQLVNKAVNQGFSFNILCLGETGLGKSTLMETLFEQNFDFTPSTHDLPEVSLKVSNFDLKEGNVKLKLSIIESCGFGDQINKEDCVNPVISYIDGEFEKYLQEEMKIKRNLYNYHDTRVHVCLYFIAPTGHTMKSLDLVAMKKLESKVSIIPVIAKSDTITKSEMQKFKAKIMNEIQSNKINIYQFPTTDDTVRELNTQMNQLLPFAVVGSNDEAKMPNGKVSRVRQYPWGTVQIDNDNHCDFIRLREMLLRTNMDDLRERTHLVHYETYRKHRLIEMGF----SDNENMSLXXXXXXXXXXXXXXXXXXXXXIRQMFFMRVKEKENQLKESDKELLAKFESLKKSNAXXXXXXXXXXXXXXXDIGNFEKRKA 1284
+E+++ +++IRTL ++GHVGFD+LP QLVNK+ +QGF FNILC+GETG+GKSTLM+T+F F+ P +H P V LK +++L+E NV+LKL+I+++ GFGDQINKE+ P++ YID +FE YLQEE+KIKR+LYNYHDTR+H CLYFIAPTGH++KSLDLV MKKL+SKV+IIP+IAK+DTI K+E+ KFK+KIMNE+ SN + IYQFPT ++TV E+N M+ LPFAVVGS +E K+ N K+++ RQYPWG VQ++N+NHCDF++LREML+R NM+DLRE+TH HYE YR+ +L EMGF D++ SLQETY+ +R EL++KEEE+RQMF MRVKEKE +LKE++KEL KF+ LK+++ EEK+KLE++++ +EE++ F+K+KA
Sbjct: 1 SEILELPSDDIRTLSMSGHVGFDSLPDQLVNKSTSQGFCFNILCVGETGIGKSTLMDTIFNTKFENEPVSHSEPAVQLKARSYELQESNVRLKLTIVDTVGFGDQINKEESYRPIVEYIDAQFEAYLQEELKIKRSLYNYHDTRIHACLYFIAPTGHSLKSLDLVTMKKLDSKVNIIPIIAKADTIAKNELHKFKSKIMNELVSNGVQIYQFPTDEETVAEINATMSVHLPFAVVGSTEEVKIGN-KMAKARQYPWGIVQVENENHCDFVKLREMLIRVNMEDLREQTHARHYELYRRCKLEEMGFKDTAPDSKPFSLQETYEAKRNEFLGELQKKEEEMRQMFVMRVKEKEAELKEAEKELHEKFDLLKRTHQEEKKKLEDKKKEIEEEVNMFQKKKA 398
BLAST of Septin-2 vs. Ensembl Xenopus
Match: rag1 (recombination activating gene 1 [Source:Xenbase;Acc:XB-GENE-6087118]) HSP 1 Score: 442.195 bits (1136), Expect = 4.599e-148 Identity = 238/397 (59.95%), Postives = 323/397 (81.36%), Query Frame = 1
Query: 106 VVKGLANEIRTLKINGHVGFDTLPYQLVNKAVNQGFSFNILCLGETGLGKSTLMETLFEQNFDFTPSTHDLPEVSLKVSNFDLKEGNVKLKLSIIESCGFGDQINKEDCVNPVISYIDGEFEKYLQEEMKIKRNLYNYHDTRVHVCLYFIAPTGHTMKSLDLVAMKKLESKVSIIPVIAKSDTITKSEMQKFKAKIMNEIQSNKINIYQFPTTDDTVRELNTQMNQLLPFAVVGSNDEAKMPNGKVSRVRQYPWGTVQIDNDNHCDFIRLREMLLRTNMDDLRERTHLVHYETYRKHRLIEMGF----SDNENMSLXXXXXXXXXXXXXXXXXXXXXIRQMFFMRVKEKENQLKESDKELLAKFESLKKSNAXXXXXXXXXXXXXXXDIGNFEKRKA 1284
V++ ++IRTL ++GHVGFD+LP QLVNK+ +QGF FNILC+GETG+GKSTLM+T+F F+ P +H P V LK +++L+E NV+LKL+I+++ GFGDQINKE+ P++ YID +FE YLQEE+KIKR+LYNYHDTR+H CLYFIAPTGH++KSLDLV MKKL+SKV+IIP+IAK+DTI K+E+ KFK+KIMNE+ SN + IYQFPT ++TV E+N M+ LPFAVVGS +E K+ N K+++ RQYPWG VQ++N+NHCDF++LREML+R NM+DLRE+TH HYE YR+ +L EMGF D++ SLQETY+ +R EL++KEEE+RQMF MRVKEKE +LKE++KEL KF+ LK+++ EEK+KLE++++ +EE++ F+K+KA
Sbjct: 6 VLEQTCDDIRTLSMSGHVGFDSLPDQLVNKSTSQGFCFNILCVGETGIGKSTLMDTIFNTKFENEPVSHSEPAVQLKARSYELQESNVRLKLTIVDTVGFGDQINKEESYRPIVEYIDAQFEAYLQEELKIKRSLYNYHDTRIHACLYFIAPTGHSLKSLDLVTMKKLDSKVNIIPIIAKADTIAKNELHKFKSKIMNELVSNGVQIYQFPTDEETVAEINATMSVHLPFAVVGSTEEVKIGN-KMAKARQYPWGIVQVENENHCDFVKLREMLIRVNMEDLREQTHARHYELYRRCKLEEMGFKDTAPDSKPFSLQETYEAKRNEFLGELQKKEEEMRQMFVMRVKEKEAELKEAEKELHEKFDLLKRTHQEEKKKLEDKKKEIEEEVNMFQKKKA 401
BLAST of Septin-2 vs. Ensembl Xenopus
Match: rag1 (recombination activating gene 1 [Source:Xenbase;Acc:XB-GENE-6087118]) HSP 1 Score: 442.195 bits (1136), Expect = 5.574e-148 Identity = 237/392 (60.46%), Postives = 321/392 (81.89%), Query Frame = 1
Query: 121 ANEIRTLKINGHVGFDTLPYQLVNKAVNQGFSFNILCLGETGLGKSTLMETLFEQNFDFTPSTHDLPEVSLKVSNFDLKEGNVKLKLSIIESCGFGDQINKEDCVNPVISYIDGEFEKYLQEEMKIKRNLYNYHDTRVHVCLYFIAPTGHTMKSLDLVAMKKLESKVSIIPVIAKSDTITKSEMQKFKAKIMNEIQSNKINIYQFPTTDDTVRELNTQMNQLLPFAVVGSNDEAKMPNGKVSRVRQYPWGTVQIDNDNHCDFIRLREMLLRTNMDDLRERTHLVHYETYRKHRLIEMGF----SDNENMSLXXXXXXXXXXXXXXXXXXXXXIRQMFFMRVKEKENQLKESDKELLAKFESLKKSNAXXXXXXXXXXXXXXXDIGNFEKRKA 1284
+++IRTL ++GHVGFD+LP QLVNK+ +QGF FNILC+GETG+GKSTLM+T+F F+ P +H P V LK +++L+E NV+LKL+I+++ GFGDQINKE+ P++ YID +FE YLQEE+KIKR+LYNYHDTR+H CLYFIAPTGH++KSLDLV MKKL+SKV+IIP+IAK+DTI K+E+ KFK+KIMNE+ SN + IYQFPT ++TV E+N M+ LPFAVVGS +E K+ N K+++ RQYPWG VQ++N+NHCDF++LREML+R NM+DLRE+TH HYE YR+ +L EMGF D++ SLQETY+ +R EL++KEEE+RQMF MRVKEKE +LKE++KEL KF+ LK+++ EEK+KLE++++ +EE++ F+K+KA
Sbjct: 12 SDDIRTLSMSGHVGFDSLPDQLVNKSTSQGFCFNILCVGETGIGKSTLMDTIFNTKFENEPVSHSEPAVQLKARSYELQESNVRLKLTIVDTVGFGDQINKEESYRPIVEYIDAQFEAYLQEELKIKRSLYNYHDTRIHACLYFIAPTGHSLKSLDLVTMKKLDSKVNIIPIIAKADTIAKNELHKFKSKIMNELVSNGVQIYQFPTDEETVAEINATMSVHLPFAVVGSTEEVKIGN-KMAKARQYPWGIVQVENENHCDFVKLREMLIRVNMEDLREQTHARHYELYRRCKLEEMGFKDTAPDSKPFSLQETYEAKRNEFLGELQKKEEEMRQMFVMRVKEKEAELKEAEKELHEKFDLLKRTHQEEKKKLEDKKKEIEEEVNMFQKKKA 402
BLAST of Septin-2 vs. Ensembl Xenopus
Match: rag1 (recombination activating gene 1 [Source:Xenbase;Acc:XB-GENE-6087118]) HSP 1 Score: 441.81 bits (1135), Expect = 6.841e-148 Identity = 237/392 (60.46%), Postives = 321/392 (81.89%), Query Frame = 1
Query: 121 ANEIRTLKINGHVGFDTLPYQLVNKAVNQGFSFNILCLGETGLGKSTLMETLFEQNFDFTPSTHDLPEVSLKVSNFDLKEGNVKLKLSIIESCGFGDQINKEDCVNPVISYIDGEFEKYLQEEMKIKRNLYNYHDTRVHVCLYFIAPTGHTMKSLDLVAMKKLESKVSIIPVIAKSDTITKSEMQKFKAKIMNEIQSNKINIYQFPTTDDTVRELNTQMNQLLPFAVVGSNDEAKMPNGKVSRVRQYPWGTVQIDNDNHCDFIRLREMLLRTNMDDLRERTHLVHYETYRKHRLIEMGF----SDNENMSLXXXXXXXXXXXXXXXXXXXXXIRQMFFMRVKEKENQLKESDKELLAKFESLKKSNAXXXXXXXXXXXXXXXDIGNFEKRKA 1284
+++IRTL ++GHVGFD+LP QLVNK+ +QGF FNILC+GETG+GKSTLM+T+F F+ P +H P V LK +++L+E NV+LKL+I+++ GFGDQINKE+ P++ YID +FE YLQEE+KIKR+LYNYHDTR+H CLYFIAPTGH++KSLDLV MKKL+SKV+IIP+IAK+DTI K+E+ KFK+KIMNE+ SN + IYQFPT ++TV E+N M+ LPFAVVGS +E K+ N K+++ RQYPWG VQ++N+NHCDF++LREML+R NM+DLRE+TH HYE YR+ +L EMGF D++ SLQETY+ +R EL++KEEE+RQMF MRVKEKE +LKE++KEL KF+ LK+++ EEK+KLE++++ +EE++ F+K+KA
Sbjct: 10 SDDIRTLSMSGHVGFDSLPDQLVNKSTSQGFCFNILCVGETGIGKSTLMDTIFNTKFENEPVSHSEPAVQLKARSYELQESNVRLKLTIVDTVGFGDQINKEESYRPIVEYIDAQFEAYLQEELKIKRSLYNYHDTRIHACLYFIAPTGHSLKSLDLVTMKKLDSKVNIIPIIAKADTIAKNELHKFKSKIMNELVSNGVQIYQFPTDEETVAEINATMSVHLPFAVVGSTEEVKIGN-KMAKARQYPWGIVQVENENHCDFVKLREMLIRVNMEDLREQTHARHYELYRRCKLEEMGFKDTAPDSKPFSLQETYEAKRNEFLGELQKKEEEMRQMFVMRVKEKEAELKEAEKELHEKFDLLKRTHQEEKKKLEDKKKEIEEEVNMFQKKKA 400
BLAST of Septin-2 vs. Ensembl Mouse
Match: Sept11 (septin 11 [Source:MGI Symbol;Acc:MGI:1277214]) HSP 1 Score: 441.039 bits (1133), Expect = 9.476e-148 Identity = 238/400 (59.50%), Postives = 323/400 (80.75%), Query Frame = 1
Query: 94 MTTEVVKGLANEIRTLKINGHVGFDTLPYQLVNKAVNQGFSFNILCLGETGLGKSTLMETLFEQNFDFTPSTHDLPEVSLKVSNFDLKEGNVKLKLSIIESCGFGDQINKEDCVNPVISYIDGEFEKYLQEEMKIKRNLYNYHDTRVHVCLYFIAPTGHTMKSLDLVAMKKLESKVSIIPVIAKSDTITKSEMQKFKAKIMNEIQSNKINIYQFPTTDDTVRELNTQMNQLLPFAVVGSNDEAKMPNGKVSRVRQYPWGTVQIDNDNHCDFIRLREMLLRTNMDDLRERTHLVHYETYRKHRLIEMGF----SDNENMSLXXXXXXXXXXXXXXXXXXXXXIRQMFFMRVKEKENQLKESDKELLAKFESLKKSNAXXXXXXXXXXXXXXXDIGNFEKRK 1281
M V + E+R L ++GHVGFD+LP QLVNK+ +QGF FNILC+GETG+GKSTLM+TLF F+ P+TH+ P V LK +++L+E NV+LKL+I+++ GFGDQINK+D P++ YID +FE YLQEE+KIKR+L+NYHDTR+H CLYFIAPTGH++KSLDLV MKKL+SKV+IIP+IAK+DTI K+E+ KFK+KIM+E+ SN + IYQFPT ++TV E+N M+ LPFAVVGS +E K+ N K+++ RQYPWG VQ++N+NHCDF++LREML+R NM+DLRE+TH HYE YR+ +L EMGF D++ SLQETY+ +R EL++KEEE+RQMF MRVKEKE +LKE++KEL KF+ LK+++ EEK+K+E++++ LEE++ NF+K+K
Sbjct: 1 MAVAVGRPSNEELRNLSLSGHVGFDSLPDQLVNKSTSQGFCFNILCVGETGIGKSTLMDTLFNTKFESDPATHNEPGVRLKARSYELQESNVRLKLTIVDTVGFGDQINKDDSYKPIVEYIDAQFEAYLQEELKIKRSLFNYHDTRIHACLYFIAPTGHSLKSLDLVTMKKLDSKVNIIPIIAKADTIAKNELHKFKSKIMSELVSNGVQIYQFPTDEETVAEINATMSVHLPFAVVGSTEEVKIGN-KMAKARQYPWGVVQVENENHCDFVKLREMLIRVNMEDLREQTHTRHYELYRRCKLEEMGFKDTDPDSKPFSLQETYEAKRNEFLGELQKKEEEMRQMFVMRVKEKEAELKEAEKELHEKFDLLKRTHQEEKKKVEDKKKELEEEVSNFQKKK 399
BLAST of Septin-2 vs. Ensembl Mouse
Match: Sept11 (septin 11 [Source:MGI Symbol;Acc:MGI:1277214]) HSP 1 Score: 441.039 bits (1133), Expect = 1.044e-147 Identity = 238/400 (59.50%), Postives = 323/400 (80.75%), Query Frame = 1
Query: 94 MTTEVVKGLANEIRTLKINGHVGFDTLPYQLVNKAVNQGFSFNILCLGETGLGKSTLMETLFEQNFDFTPSTHDLPEVSLKVSNFDLKEGNVKLKLSIIESCGFGDQINKEDCVNPVISYIDGEFEKYLQEEMKIKRNLYNYHDTRVHVCLYFIAPTGHTMKSLDLVAMKKLESKVSIIPVIAKSDTITKSEMQKFKAKIMNEIQSNKINIYQFPTTDDTVRELNTQMNQLLPFAVVGSNDEAKMPNGKVSRVRQYPWGTVQIDNDNHCDFIRLREMLLRTNMDDLRERTHLVHYETYRKHRLIEMGF----SDNENMSLXXXXXXXXXXXXXXXXXXXXXIRQMFFMRVKEKENQLKESDKELLAKFESLKKSNAXXXXXXXXXXXXXXXDIGNFEKRK 1281
M V + E+R L ++GHVGFD+LP QLVNK+ +QGF FNILC+GETG+GKSTLM+TLF F+ P+TH+ P V LK +++L+E NV+LKL+I+++ GFGDQINK+D P++ YID +FE YLQEE+KIKR+L+NYHDTR+H CLYFIAPTGH++KSLDLV MKKL+SKV+IIP+IAK+DTI K+E+ KFK+KIM+E+ SN + IYQFPT ++TV E+N M+ LPFAVVGS +E K+ N K+++ RQYPWG VQ++N+NHCDF++LREML+R NM+DLRE+TH HYE YR+ +L EMGF D++ SLQETY+ +R EL++KEEE+RQMF MRVKEKE +LKE++KEL KF+ LK+++ EEK+K+E++++ LEE++ NF+K+K
Sbjct: 1 MAVAVGRPSNEELRNLSLSGHVGFDSLPDQLVNKSTSQGFCFNILCVGETGIGKSTLMDTLFNTKFESDPATHNEPGVRLKARSYELQESNVRLKLTIVDTVGFGDQINKDDSYKPIVEYIDAQFEAYLQEELKIKRSLFNYHDTRIHACLYFIAPTGHSLKSLDLVTMKKLDSKVNIIPIIAKADTIAKNELHKFKSKIMSELVSNGVQIYQFPTDEETVAEINATMSVHLPFAVVGSTEEVKIGN-KMAKARQYPWGVVQVENENHCDFVKLREMLIRVNMEDLREQTHTRHYELYRRCKLEEMGFKDTDPDSKPFSLQETYEAKRNEFLGELQKKEEEMRQMFVMRVKEKEAELKEAEKELHEKFDLLKRTHQEEKKKVEDKKKELEEEVSNFQKKK 399
BLAST of Septin-2 vs. Ensembl Mouse
Match: Sept11 (septin 11 [Source:MGI Symbol;Acc:MGI:1277214]) HSP 1 Score: 441.039 bits (1133), Expect = 1.159e-147 Identity = 238/400 (59.50%), Postives = 323/400 (80.75%), Query Frame = 1
Query: 94 MTTEVVKGLANEIRTLKINGHVGFDTLPYQLVNKAVNQGFSFNILCLGETGLGKSTLMETLFEQNFDFTPSTHDLPEVSLKVSNFDLKEGNVKLKLSIIESCGFGDQINKEDCVNPVISYIDGEFEKYLQEEMKIKRNLYNYHDTRVHVCLYFIAPTGHTMKSLDLVAMKKLESKVSIIPVIAKSDTITKSEMQKFKAKIMNEIQSNKINIYQFPTTDDTVRELNTQMNQLLPFAVVGSNDEAKMPNGKVSRVRQYPWGTVQIDNDNHCDFIRLREMLLRTNMDDLRERTHLVHYETYRKHRLIEMGF----SDNENMSLXXXXXXXXXXXXXXXXXXXXXIRQMFFMRVKEKENQLKESDKELLAKFESLKKSNAXXXXXXXXXXXXXXXDIGNFEKRK 1281
M V + E+R L ++GHVGFD+LP QLVNK+ +QGF FNILC+GETG+GKSTLM+TLF F+ P+TH+ P V LK +++L+E NV+LKL+I+++ GFGDQINK+D P++ YID +FE YLQEE+KIKR+L+NYHDTR+H CLYFIAPTGH++KSLDLV MKKL+SKV+IIP+IAK+DTI K+E+ KFK+KIM+E+ SN + IYQFPT ++TV E+N M+ LPFAVVGS +E K+ N K+++ RQYPWG VQ++N+NHCDF++LREML+R NM+DLRE+TH HYE YR+ +L EMGF D++ SLQETY+ +R EL++KEEE+RQMF MRVKEKE +LKE++KEL KF+ LK+++ EEK+K+E++++ LEE++ NF+K+K
Sbjct: 1 MAVAVGRPSNEELRNLSLSGHVGFDSLPDQLVNKSTSQGFCFNILCVGETGIGKSTLMDTLFNTKFESDPATHNEPGVRLKARSYELQESNVRLKLTIVDTVGFGDQINKDDSYKPIVEYIDAQFEAYLQEELKIKRSLFNYHDTRIHACLYFIAPTGHSLKSLDLVTMKKLDSKVNIIPIIAKADTIAKNELHKFKSKIMSELVSNGVQIYQFPTDEETVAEINATMSVHLPFAVVGSTEEVKIGN-KMAKARQYPWGVVQVENENHCDFVKLREMLIRVNMEDLREQTHTRHYELYRRCKLEEMGFKDTDPDSKPFSLQETYEAKRNEFLGELQKKEEEMRQMFVMRVKEKEAELKEAEKELHEKFDLLKRTHQEEKKKVEDKKKELEEEVSNFQKKK 399
BLAST of Septin-2 vs. Ensembl Mouse
Match: Sept11 (septin 11 [Source:MGI Symbol;Acc:MGI:1277214]) HSP 1 Score: 440.654 bits (1132), Expect = 1.930e-147 Identity = 238/400 (59.50%), Postives = 323/400 (80.75%), Query Frame = 1
Query: 94 MTTEVVKGLANEIRTLKINGHVGFDTLPYQLVNKAVNQGFSFNILCLGETGLGKSTLMETLFEQNFDFTPSTHDLPEVSLKVSNFDLKEGNVKLKLSIIESCGFGDQINKEDCVNPVISYIDGEFEKYLQEEMKIKRNLYNYHDTRVHVCLYFIAPTGHTMKSLDLVAMKKLESKVSIIPVIAKSDTITKSEMQKFKAKIMNEIQSNKINIYQFPTTDDTVRELNTQMNQLLPFAVVGSNDEAKMPNGKVSRVRQYPWGTVQIDNDNHCDFIRLREMLLRTNMDDLRERTHLVHYETYRKHRLIEMGF----SDNENMSLXXXXXXXXXXXXXXXXXXXXXIRQMFFMRVKEKENQLKESDKELLAKFESLKKSNAXXXXXXXXXXXXXXXDIGNFEKRK 1281
M V + E+R L ++GHVGFD+LP QLVNK+ +QGF FNILC+GETG+GKSTLM+TLF F+ P+TH+ P V LK +++L+E NV+LKL+I+++ GFGDQINK+D P++ YID +FE YLQEE+KIKR+L+NYHDTR+H CLYFIAPTGH++KSLDLV MKKL+SKV+IIP+IAK+DTI K+E+ KFK+KIM+E+ SN + IYQFPT ++TV E+N M+ LPFAVVGS +E K+ N K+++ RQYPWG VQ++N+NHCDF++LREML+R NM+DLRE+TH HYE YR+ +L EMGF D++ SLQETY+ +R EL++KEEE+RQMF MRVKEKE +LKE++KEL KF+ LK+++ EEK+K+E++++ LEE++ NF+K+K
Sbjct: 1 MAVAVGRPSNEELRNLSLSGHVGFDSLPDQLVNKSTSQGFCFNILCVGETGIGKSTLMDTLFNTKFESDPATHNEPGVRLKARSYELQESNVRLKLTIVDTVGFGDQINKDDSYKPIVEYIDAQFEAYLQEELKIKRSLFNYHDTRIHACLYFIAPTGHSLKSLDLVTMKKLDSKVNIIPIIAKADTIAKNELHKFKSKIMSELVSNGVQIYQFPTDEETVAEINATMSVHLPFAVVGSTEEVKIGN-KMAKARQYPWGVVQVENENHCDFVKLREMLIRVNMEDLREQTHTRHYELYRRCKLEEMGFKDTDPDSKPFSLQETYEAKRNEFLGELQKKEEEMRQMFVMRVKEKEAELKEAEKELHEKFDLLKRTHQEEKKKVEDKKKELEEEVSNFQKKK 399
BLAST of Septin-2 vs. Ensembl Mouse
Match: Sept11 (septin 11 [Source:MGI Symbol;Acc:MGI:1277214]) HSP 1 Score: 440.654 bits (1132), Expect = 1.954e-147 Identity = 238/400 (59.50%), Postives = 323/400 (80.75%), Query Frame = 1
Query: 94 MTTEVVKGLANEIRTLKINGHVGFDTLPYQLVNKAVNQGFSFNILCLGETGLGKSTLMETLFEQNFDFTPSTHDLPEVSLKVSNFDLKEGNVKLKLSIIESCGFGDQINKEDCVNPVISYIDGEFEKYLQEEMKIKRNLYNYHDTRVHVCLYFIAPTGHTMKSLDLVAMKKLESKVSIIPVIAKSDTITKSEMQKFKAKIMNEIQSNKINIYQFPTTDDTVRELNTQMNQLLPFAVVGSNDEAKMPNGKVSRVRQYPWGTVQIDNDNHCDFIRLREMLLRTNMDDLRERTHLVHYETYRKHRLIEMGF----SDNENMSLXXXXXXXXXXXXXXXXXXXXXIRQMFFMRVKEKENQLKESDKELLAKFESLKKSNAXXXXXXXXXXXXXXXDIGNFEKRK 1281
M V + E+R L ++GHVGFD+LP QLVNK+ +QGF FNILC+GETG+GKSTLM+TLF F+ P+TH+ P V LK +++L+E NV+LKL+I+++ GFGDQINK+D P++ YID +FE YLQEE+KIKR+L+NYHDTR+H CLYFIAPTGH++KSLDLV MKKL+SKV+IIP+IAK+DTI K+E+ KFK+KIM+E+ SN + IYQFPT ++TV E+N M+ LPFAVVGS +E K+ N K+++ RQYPWG VQ++N+NHCDF++LREML+R NM+DLRE+TH HYE YR+ +L EMGF D++ SLQETY+ +R EL++KEEE+RQMF MRVKEKE +LKE++KEL KF+ LK+++ EEK+K+E++++ LEE++ NF+K+K
Sbjct: 1 MAVAVGRPSNEELRNLSLSGHVGFDSLPDQLVNKSTSQGFCFNILCVGETGIGKSTLMDTLFNTKFESDPATHNEPGVRLKARSYELQESNVRLKLTIVDTVGFGDQINKDDSYKPIVEYIDAQFEAYLQEELKIKRSLFNYHDTRIHACLYFIAPTGHSLKSLDLVTMKKLDSKVNIIPIIAKADTIAKNELHKFKSKIMSELVSNGVQIYQFPTDEETVAEINATMSVHLPFAVVGSTEEVKIGN-KMAKARQYPWGVVQVENENHCDFVKLREMLIRVNMEDLREQTHTRHYELYRRCKLEEMGFKDTDPDSKPFSLQETYEAKRNEFLGELQKKEEEMRQMFVMRVKEKEAELKEAEKELHEKFDLLKRTHQEEKKKVEDKKKELEEEVSNFQKKK 399
BLAST of Septin-2 vs. UniProt/SwissProt
Match: sp|P54359|SEPT2_DROME (Septin-2 OS=Drosophila melanogaster OX=7227 GN=Sep2 PE=2 SV=2) HSP 1 Score: 464.922 bits (1195), Expect = 2.834e-156 Identity = 244/404 (60.40%), Postives = 317/404 (78.47%), Query Frame = 1
Query: 130 IRTLKINGHVGFDTLPYQLVNKAVNQGFSFNILCLGETGLGKSTLMETLFEQNFDFTPSTHDLPEVSLKVSNFDLKEGNVKLKLSIIESCGFGDQINKEDCVNPVISYIDGEFEKYLQEEMKIKRNLYNYHDTRVHVCLYFIAPTGHTMKSLDLVAMKKLESKVSIIPVIAKSDTITKSEMQKFKAKIMNEIQSNKINIYQFPTTDDTVRELNTQMNQLLPFAVVGSNDEAKMPNGKVSRVRQYPWGTVQIDNDNHCDFIRLREMLLRTNMDDLRERTHLVHYETYRKHRLIEMGF----SDNENMSLXXXXXXXXXXXXXXXXXXXXXIRQMFFMRVKEKENQLKESDKELLAKFESLKKSNAXXXXXXXXXXXXXXXDIGNFEKRKAIVEQAKQGNTIKKKK 1329
+RTLK +GHVGFD+LP QLVNK+V GF FN++C+GETGLGKSTLM+TLF +F+ TPS H LP V LK ++L+E NV+LKL+I ++ G+GDQINK+D V+ YID +FE YLQEE+KIKR+L HD+R+H+CLYFI PTGH +KSLDLV MKKL+SKV+IIPVIAK+DTI+K E+Q+FKAKI+ E+ +N ++IYQFPT D+TV E NT MN +PFAVVGS + K+ N K+ R RQYPWGTVQ++N+ HCDF++LREML+RTNM+D+RE+TH HYE YR+ RL +MGF SDN+ +S Q+T++ +R EL+ KEEE+RQMF RVKEKE +LKES+K+L AKFE LK+ +AEEKRKLEE R+ LEED +F++RK + A T+ K K
Sbjct: 15 LRTLKQSGHVGFDSLPDQLVNKSVQNGFVFNVMCIGETGLGKSTLMDTLFNTSFESTPSPHTLPSVKLKAHTYELQESNVRLKLTICDTVGYGDQINKDDSFKAVVDYIDAQFENYLQEELKIKRSLVTCHDSRIHICLYFICPTGHGLKSLDLVCMKKLDSKVNIIPVIAKADTISKVELQRFKAKIIQELNANGVHIYQFPTDDETVAETNTSMNSHIPFAVVGSTEFIKVGN-KLIRARQYPWGTVQVENETHCDFVKLREMLIRTNMEDMREKTHTRHYELYRQKRLEQMGFSDVDSDNKPISFQQTFEAKRSNHLAELQSKEEEVRQMFVQRVKEKEAELKESEKDLHAKFEKLKRDHAEEKRKLEESRKALEEDYLDFQRRKQQLATAHHTLTLGKSK 417
BLAST of Septin-2 vs. UniProt/SwissProt
Match: sp|A4FUM1|SEP8B_DANRE (Septin-8-B OS=Danio rerio OX=7955 GN=sept8b PE=2 SV=1) HSP 1 Score: 450.669 bits (1158), Expect = 1.145e-150 Identity = 238/416 (57.21%), Postives = 320/416 (76.92%), Query Frame = 1
Query: 97 TTEVVKGLANEIRTLKINGHVGFDTLPYQLVNKAVNQGFSFNILCLGETGLGKSTLMETLFEQNFDFTPSTHDLPEVSLKVSNFDLKEGNVKLKLSIIESCGFGDQINKEDCVNPVISYIDGEFEKYLQEEMKIKRNLYNYHDTRVHVCLYFIAPTGHTMKSLDLVAMKKLESKVSIIPVIAKSDTITKSEMQKFKAKIMNEIQSNKINIYQFPTTDDTVRELNTQMNQLLPFAVVGSNDEAKMPNGKVSRVRQYPWGTVQIDNDNHCDFIRLREMLLRTNMDDLRERTHLVHYETYRKHRLIEMGF----SDNENMSLXXXXXXXXXXXXXXXXXXXXXIRQMFFMRVKEKENQLKESDKELLAKFESLKKSNAXXXXXXXXXXXXXXXDIGNFEKRKAIVE--QAKQGNTIKKK 1326
TEV E+R+L ++GHVGFD+LP QLV+K+V+QGFSFNILC+GETG+GKSTLM TLF F+ ++H V L+ + L+E NV L+L+I+++ GFGDQ+NKE+ P++ YID +FE +L+EE+KIKR+LYNYHD+R+H+CLYFIAPTGH++KSLDLV MKKL+SKV+IIP+IAK+DT++KSE+QKFK KIM+E+ SN + IYQFPT D+ V E+N+ MN LPFAV+GS++E K+ N K+ R RQYPWG VQ++N++HCDF++LREML+R NM DLRE+TH HYE YR+ +L EMGF +D+E SLQETY +R EL+ KEE++RQMF +VKE E +LKE ++EL +FE LK+++ EEKR LEE RR EE++ F +RK E Q+ QG+T KK
Sbjct: 3 ATEVNTYPTEEMRSLSLSGHVGFDSLPDQLVSKSVSQGFSFNILCVGETGIGKSTLMNTLFNTTFENEEASHFHNGVHLRPRTYSLQESNVDLQLTIVDTVGFGDQVNKEESYKPIVDYIDAQFENFLEEELKIKRSLYNYHDSRIHICLYFIAPTGHSLKSLDLVTMKKLDSKVNIIPIIAKADTVSKSELQKFKIKIMSELVSNGVQIYQFPTDDEAVAEINSSMNAHLPFAVIGSSEEVKIGN-KMVRARQYPWGVVQVENESHCDFVKLREMLIRVNMLDLREQTHARHYELYRRCKLEEMGFKDTDADSEPFSLQETYVAKRREFIVELQMKEEQMRQMFVNKVKETEAELKEKERELHERFEMLKRTHQEEKRSLEEMRRDFEEEMNTFNRRKVAAETLQSLQGSTGLKK 417
BLAST of Septin-2 vs. UniProt/SwissProt
Match: sp|Q9P0V9|SEP10_HUMAN (Septin-10 OS=Homo sapiens OX=9606 GN=SEPTIN10 PE=1 SV=2) HSP 1 Score: 448.358 bits (1152), Expect = 2.503e-149 Identity = 233/392 (59.44%), Postives = 315/392 (80.36%), Query Frame = 1
Query: 130 IRTLKINGHVGFDTLPYQLVNKAVNQGFSFNILCLGETGLGKSTLMETLFEQNFDFTPSTHDLPEVSLKVSNFDLKEGNVKLKLSIIESCGFGDQINKEDCVNPVISYIDGEFEKYLQEEMKIKRNLYNYHDTRVHVCLYFIAPTGHTMKSLDLVAMKKLESKVSIIPVIAKSDTITKSEMQKFKAKIMNEIQSNKINIYQFPTTDDTVRELNTQMNQLLPFAVVGSNDEAKMPNGKVSRVRQYPWGTVQIDNDNHCDFIRLREMLLRTNMDDLRERTHLVHYETYRKHRLIEMGFSD----NENMSLXXXXXXXXXXXXXXXXXXXXXIRQMFFMRVKEKENQLKESDKELLAKFESLKKSNAXXXXXXXXXXXXXXXDIGNFEKRKAIVE 1293
IR+L ++GHVGF++LP QLVN+++ QGF FNILC+GETG+GKSTL++TLF NF+ S+H P V LK ++L+E NV+LKL+I+ + GFGDQINKE+ P++ YID +FE YLQEE+KIKR+L+ YHD+R+HVCLYFI+PTGH++K+LDL+ MK L+SKV+IIPVIAK+DT++K+E+QKFK K+M+E+ SN + IYQFPT DDT+ ++N MN LPFAVVGS DE K+ N K+ + RQYPWG VQ++N+NHCDF++LREML+ TNM+DLRE+TH HYE YR+ +L EMGF+D N+ +S+QETY+ +R E ++KEEE++QMF RVKEKE LKE+++EL AKFE LK+ + EE+ KLEE+RR+LEE+I F K+KA E
Sbjct: 38 IRSLTMSGHVGFESLPDQLVNRSIQQGFCFNILCVGETGIGKSTLIDTLFNTNFEDYESSHFCPNVKLKAQTYELQESNVQLKLTIVNTVGFGDQINKEESYQPIVDYIDAQFEAYLQEELKIKRSLFTYHDSRIHVCLYFISPTGHSLKTLDLLTMKNLDSKVNIIPVIAKADTVSKTELQKFKIKLMSELVSNGVQIYQFPTDDDTIAKVNAAMNGQLPFAVVGSMDEVKVGN-KMVKARQYPWGVVQVENENHCDFVKLREMLICTNMEDLREQTHTRHYELYRRCKLEEMGFTDVGPENKPVSVQETYEAKRHEFHGERQRKEEEMKQMFVQRVKEKEAILKEAERELQAKFEHLKRLHQEERMKLEEKRRLLEEEIIAFSKKKATSE 428
BLAST of Septin-2 vs. UniProt/SwissProt
Match: sp|Q2KJB1|SEP10_BOVIN (Septin-10 OS=Bos taurus OX=9913 GN=SEPTIN10 PE=2 SV=1) HSP 1 Score: 447.203 bits (1149), Expect = 6.737e-149 Identity = 232/391 (59.34%), Postives = 313/391 (80.05%), Query Frame = 1
Query: 133 RTLKINGHVGFDTLPYQLVNKAVNQGFSFNILCLGETGLGKSTLMETLFEQNFDFTPSTHDLPEVSLKVSNFDLKEGNVKLKLSIIESCGFGDQINKEDCVNPVISYIDGEFEKYLQEEMKIKRNLYNYHDTRVHVCLYFIAPTGHTMKSLDLVAMKKLESKVSIIPVIAKSDTITKSEMQKFKAKIMNEIQSNKINIYQFPTTDDTVRELNTQMNQLLPFAVVGSNDEAKMPNGKVSRVRQYPWGTVQIDNDNHCDFIRLREMLLRTNMDDLRERTHLVHYETYRKHRLIEMGFSD----NENMSLXXXXXXXXXXXXXXXXXXXXXIRQMFFMRVKEKENQLKESDKELLAKFESLKKSNAXXXXXXXXXXXXXXXDIGNFEKRKAIVE 1293
R+L ++GHVGF++LP QLVN+++ QGF FNILC+GETG+GKSTL++TLF NF+ S+H P V LK ++L+E NV+LKL+I+ + GFGDQINKE+ P++ YID +FE YLQEE+KIKR+L+NYHD+RVHVCLYFI+PTGH++K+LDL+ MK L+SKV+IIPVIAK+D I+K+E+QKFK K+M+E+ SN + IYQFPT D+T+ ++N MN LPFAVVGS DE K+ N K+ + RQYPWG VQ++N+NHCDF++LREML+ TNM+DLR++TH HYE YR+ +L EMGF D N+ +SLQETY+ +R E ++KEEE++Q+F RVKEKE LKE+++EL AKFE LK+ + EEK +LEE+RR+LEE+I F K+KA E
Sbjct: 38 RSLTMSGHVGFESLPDQLVNRSIQQGFCFNILCVGETGIGKSTLIDTLFNTNFEDHESSHFYPHVRLKAQTYELQESNVRLKLTIVNTVGFGDQINKEESYQPIVDYIDAQFEAYLQEELKIKRSLFNYHDSRVHVCLYFISPTGHSLKTLDLLTMKSLDSKVNIIPVIAKADAISKTELQKFKIKLMSELVSNGVQIYQFPTDDETIAKINASMNGHLPFAVVGSMDEVKVGN-KMVKARQYPWGVVQVENENHCDFVKLREMLICTNMEDLRDQTHTRHYELYRRRKLEEMGFMDVGPENQPLSLQETYEAKRHEFYGERQRKEEEMKQLFVQRVKEKEAILKEAERELQAKFEHLKRVHQEEKLRLEEKRRLLEEEIMAFSKKKATSE 427
BLAST of Septin-2 vs. UniProt/SwissProt
Match: sp|Q6AXA6|SEP8A_XENLA (Septin-8-A OS=Xenopus laevis OX=8355 GN=sept8-a PE=2 SV=1) HSP 1 Score: 444.121 bits (1141), Expect = 4.211e-148 Identity = 239/422 (56.64%), Postives = 319/422 (75.59%), Query Frame = 1
Query: 97 TTEVVKGLANEIRTLKINGHVGFDTLPYQLVNKAVNQGFSFNILCLGETGLGKSTLMETLFEQNFDFTPSTHDLPEVSLKVSNFDLKEGNVKLKLSIIESCGFGDQINKEDCVNPVISYIDGEFEKYLQEEMKIKRNLYNYHDTRVHVCLYFIAPTGHTMKSLDLVAMKKLESKVSIIPVIAKSDTITKSEMQKFKAKIMNEIQSNKINIYQFPTTDDTVRELNTQMNQLLPFAVVGSNDEAKMPNGKVSRVRQYPWGTVQIDNDNHCDFIRLREMLLRTNMDDLRERTHLVHYETYRKHRLIEMGFSDN----ENMSLXXXXXXXXXXXXXXXXXXXXXIRQMFFMRVKEKENQLKESDKELLAKFESLKKSNAXXXXXXXXXXXXXXXDIGNFEKRKAIVE-------QAKQGNTIKKKK 1329
T+V + E R+L ++GHVGFD+LP QLV+K+V QGF FNILC+GETG+GKSTLM TLF F+ ++H V L+ +DL+E NV LKL+I+++ GFGDQINK+D V+ YID +FE YLQEE+KI+R+L+N+HD+R+HVCLYFI PTGH++KSLDLV MKKL+SKV+IIP+IAK+DTI+KSE+ KFK KIM+E+ SN + IYQFPT DD V E+N+ MN LPFAVVGS +E K+ N K+ R RQYPWG VQ++N++HCDF++LREML+R NM+DLRE+TH HYE YR+ +L EMGF DN + SLQETY+ +R+ EL++KEEE+RQMF +VKE E +LKE ++EL KF LK+ + EE +K+E++RR LEE++ +F +RKA +E QA +KK K
Sbjct: 3 ATDVQRASNEEKRSLAMSGHVGFDSLPDQLVSKSVTQGFCFNILCVGETGIGKSTLMNTLFNTTFETEEASHYENGVCLRPRTYDLQESNVHLKLTIVDTVGFGDQINKDDSYRSVVDYIDTQFENYLQEELKIRRSLFNFHDSRIHVCLYFITPTGHSLKSLDLVTMKKLDSKVNIIPIIAKADTISKSELHKFKIKIMSELVSNGVQIYQFPTDDDAVAEINSVMNAHLPFAVVGSTEEVKVGN-KLVRARQYPWGVVQVENESHCDFVKLREMLIRVNMEDLREQTHTRHYELYRRCKLEEMGFKDNDPDTQPFSLQETYEAKRKEFLSELQRKEEEMRQMFVNKVKETEAELKERERELQEKFMQLKRIHQEESKKVEDKRRDLEEEMNSFNRRKAAMEALQSQSFQATSQQPLKKDK 423
BLAST of Septin-2 vs. TrEMBL
Match: A0A4E0RBQ8 (Septin-2 OS=Fasciola hepatica OX=6192 GN=D915_005619 PE=3 SV=1) HSP 1 Score: 564.688 bits (1454), Expect = 0.000e+0 Identity = 292/408 (71.57%), Postives = 363/408 (88.97%), Query Frame = 1
Query: 109 VKGLANEIRTLKINGHVGFDTLPYQLVNKAVNQGFSFNILCLGETGLGKSTLMETLFEQNFDFTPSTHDLPEVSLKVSNFDLKEGNVKLKLSIIESCGFGDQINKEDCVNPVISYIDGEFEKYLQEEMKIKRNLYNYHDTRVHVCLYFIAPTGHTMKSLDLVAMKKLESKVSIIPVIAKSDTITKSEMQKFKAKIMNEIQSNKINIYQFPTTDDTVRELNTQMNQLLPFAVVGSNDEAKMPNGKVSRVRQYPWGTVQIDNDNHCDFIRLREMLLRTNMDDLRERTHLVHYETYRKHRLIEMGFSDNENMSLXXXXXXXXXXXXXXXXXXXXXIRQMFFMRVKEKENQLKESDKELLAKFESLKKSNAXXXXXXXXXXXXXXXDIGNFEKRKAIVEQAKQGN-TIKKKK 1329
VK + E+RTLK++GHVGFD+LP QLVNKAV+QGFSFNILC+GETG+GKSTL+ETLF Q FDF PS HDLP LK S F+LKEGNVKLKLS++E+CGFGDQ+NKED + PVI Y++ +FEKYLQEE+K+KR+L N+HDTR+HVCLYFIAPTGH++KSLD+VAMK LESKV++IP+IAKSDT+TK E+QKFKA+I++EIQSN+INIYQFPT D+TV ++NT+MNQ +PFAVVGS +E K+ NGK +RVRQYPWG VQ+DN++HCDF+RLREMLLR NM+DLRERTH V+YETYR+ RLIEMGF D+E MSLQETY++RRE Q KEL+QKEEE+RQ+F RVKEKE LKE+++EL AKFE+LKK++AEEK+KLE+++RILEE++ FE+RK + EQAKQGN T+KKKK
Sbjct: 5 VKAITGEVRTLKLSGHVGFDSLPNQLVNKAVSQGFSFNILCVGETGIGKSTLIETLFNQKFDFVPSLHDLPNPKLKESFFELKEGNVKLKLSVVETCGFGDQLNKEDNIKPVIDYVNSQFEKYLQEELKMKRSLQNFHDTRIHVCLYFIAPTGHSLKSLDVVAMKALESKVNVIPIIAKSDTVTKVELQKFKARILSEIQSNEINIYQFPTDDETVSDVNTKMNQHVPFAVVGSGEEIKI-NGKNARVRQYPWGAVQVDNESHCDFVRLREMLLRVNMEDLRERTHTVNYETYRRQRLIEMGFRDDEKMSLQETYEKRRELQRKELQQKEEEMRQLFVQRVKEKEQVLKEAERELQAKFEALKKNHAEEKKKLEDKKRILEEEMAAFERRKLLAEQAKQGNFTMKKKK 411
BLAST of Septin-2 vs. TrEMBL
Match: G4VFI8 (Putative septin OS=Schistosoma mansoni OX=6183 GN=Smp_029890 PE=1 SV=1) HSP 1 Score: 561.222 bits (1445), Expect = 0.000e+0 Identity = 289/413 (69.98%), Postives = 361/413 (87.41%), Query Frame = 1
Query: 94 MTTEVVKGLANEIRTLKINGHVGFDTLPYQLVNKAVNQGFSFNILCLGETGLGKSTLMETLFEQNFDFTPSTHDLPEVSLKVSNFDLKEGNVKLKLSIIESCGFGDQINKEDCVNPVISYIDGEFEKYLQEEMKIKRNLYNYHDTRVHVCLYFIAPTGHTMKSLDLVAMKKLESKVSIIPVIAKSDTITKSEMQKFKAKIMNEIQSNKINIYQFPTTDDTVRELNTQMNQLLPFAVVGSNDEAKMPNGKVSRVRQYPWGTVQIDNDNHCDFIRLREMLLRTNMDDLRERTHLVHYETYRKHRLIEMGFSDNENMSLXXXXXXXXXXXXXXXXXXXXXIRQMFFMRVKEKENQLKESDKELLAKFESLKKSNAXXXXXXXXXXXXXXXDIGNFEKRKAIVEQAKQGN-TIKKKK 1329
MT +V+K L ++RTLK++GHVGFD+LP QLVNKA++QGF FNILC+GETG+GKSTL+ETLF Q FDF+PSTHDL + LK +DLKE NVKLKL+++E+CG+GDQINKE+ + PV+ YID +FE YLQEE+K+KR++ +HDTRVHVCLYFIAPTGH++KS+DLVAMKKLE+KV++IPVIAKSDTITKSE+QKFKA+I++EIQSN+I IYQFPT D+ V E N+ MNQ +PFAVVGS++E K+ NGK RVRQYPWG+VQ++N+NHCDF+RLREMLLR NM+DLRERTH VHYETYR+ RLIEMGF D+E MSLQETY++RRE Q KEL+QKEEE+RQMF RVKEKE LKE+++EL KFESLKK++AEEK+KLEE++R LEE+I FE+RK + EQA+QGN T+KK+K
Sbjct: 1 MTADVLKALPPDVRTLKLSGHVGFDSLPDQLVNKAISQGFVFNILCVGETGIGKSTLLETLFNQKFDFSPSTHDLTDPKLKAVTYDLKEANVKLKLTVVETCGYGDQINKENNIKPVVDYIDNQFENYLQEELKMKRSMQAFHDTRVHVCLYFIAPTGHSLKSIDLVAMKKLENKVNVIPVIAKSDTITKSELQKFKARILSEIQSNEIGIYQFPTDDEAVSETNSVMNQHIPFAVVGSSEEVKI-NGKTVRVRQYPWGSVQVENENHCDFVRLREMLLRVNMEDLRERTHGVHYETYRRQRLIEMGFRDDEKMSLQETYEKRRELQRKELQQKEEEMRQMFVQRVKEKEQVLKEAERELQTKFESLKKTHAEEKKKLEEKKRFLEEEIAAFERRKQLAEQARQGNLTMKKRK 412
BLAST of Septin-2 vs. TrEMBL
Match: Q5DDA5 (SJCHGC01523 protein OS=Schistosoma japonicum OX=6182 GN=EWB00_003989 PE=2 SV=1) HSP 1 Score: 558.91 bits (1439), Expect = 0.000e+0 Identity = 289/413 (69.98%), Postives = 359/413 (86.92%), Query Frame = 1
Query: 94 MTTEVVKGLANEIRTLKINGHVGFDTLPYQLVNKAVNQGFSFNILCLGETGLGKSTLMETLFEQNFDFTPSTHDLPEVSLKVSNFDLKEGNVKLKLSIIESCGFGDQINKEDCVNPVISYIDGEFEKYLQEEMKIKRNLYNYHDTRVHVCLYFIAPTGHTMKSLDLVAMKKLESKVSIIPVIAKSDTITKSEMQKFKAKIMNEIQSNKINIYQFPTTDDTVRELNTQMNQLLPFAVVGSNDEAKMPNGKVSRVRQYPWGTVQIDNDNHCDFIRLREMLLRTNMDDLRERTHLVHYETYRKHRLIEMGFSDNENMSLXXXXXXXXXXXXXXXXXXXXXIRQMFFMRVKEKENQLKESDKELLAKFESLKKSNAXXXXXXXXXXXXXXXDIGNFEKRKAIVEQAKQGN-TIKKKK 1329
MT +V+K L ++RTLK+ GHVGFD+LP QLVNKA++QGF FNILC+GETG+GKSTL+ETLF Q FDF+PSTHDL + LK +DLKE NVKLKL+++E+CG+GDQINKE+ + PVI YI +FE YLQEE+K+KR++ +HDTRVH CLYFIAPTGH++KS+DLVAMKKLE+KV++IP+IAKSDTITKSE+QKFKA+I+NEIQSN+I IYQFPT D+ V E N+ MNQ +PFA+VGS++E K+ NGK RVRQYPWG+VQ++N+NHCDF+RLREMLLR NM+DLRERTH VHYETYR+ RLIEMGF D+E MSLQETY++RRE Q KEL+QKEEE+RQMF RVKEKE LKE+++EL KFE+LKK++AEEK+KLEE++RILEE+I FE+RK + EQA+QGN TIKKKK
Sbjct: 1 MTADVLKSLPPDVRTLKLTGHVGFDSLPDQLVNKAISQGFVFNILCVGETGIGKSTLLETLFNQKFDFSPSTHDLADPKLKAVTYDLKEANVKLKLTVVETCGYGDQINKENNIKPVIDYISNQFENYLQEELKMKRSMQAFHDTRVHACLYFIAPTGHSLKSIDLVAMKKLENKVNVIPIIAKSDTITKSELQKFKARILNEIQSNEIGIYQFPTDDEAVSETNSAMNQHIPFAIVGSSEETKI-NGKTVRVRQYPWGSVQVENENHCDFVRLREMLLRVNMEDLRERTHGVHYETYRRQRLIEMGFRDDEKMSLQETYEKRRELQRKELQQKEEEMRQMFVQRVKEKEQVLKEAERELQTKFENLKKTHAEEKKKLEEKKRILEEEIAAFERRKQLAEQARQGNLTIKKKK 412
BLAST of Septin-2 vs. TrEMBL
Match: A0A3Q0KDV9 (Putative septin; Septin-10 OS=Schistosoma mansoni OX=6183 PE=3 SV=1) HSP 1 Score: 558.14 bits (1437), Expect = 0.000e+0 Identity = 288/413 (69.73%), Postives = 360/413 (87.17%), Query Frame = 1
Query: 94 MTTEVVKGLANEIRTLKINGHVGFDTLPYQLVNKAVNQGFSFNILCLGETGLGKSTLMETLFEQNFDFTPSTHDLPEVSLKVSNFDLKEGNVKLKLSIIESCGFGDQINKEDCVNPVISYIDGEFEKYLQEEMKIKRNLYNYHDTRVHVCLYFIAPTGHTMKSLDLVAMKKLESKVSIIPVIAKSDTITKSEMQKFKAKIMNEIQSNKINIYQFPTTDDTVRELNTQMNQLLPFAVVGSNDEAKMPNGKVSRVRQYPWGTVQIDNDNHCDFIRLREMLLRTNMDDLRERTHLVHYETYRKHRLIEMGFSDNENMSLXXXXXXXXXXXXXXXXXXXXXIRQMFFMRVKEKENQLKESDKELLAKFESLKKSNAXXXXXXXXXXXXXXXDIGNFEKRKAIVEQAKQGN-TIKKKK 1329
MT +V+K L ++RTLK++GHVGFD+LP QLVNKA++QGF FNILC+GETG+GKSTL+ETLF Q FDF+PS HDL + LK +DLKE NVKLKL+++E+CG+GDQINKE+ + PV+ YID +FE YLQEE+K+KR++ +HDTRVHVCLYFIAPTGH++KS+DLVAMKKLE+KV++IPVIAKSDTITKSE+QKFKA+I++EIQSN+I IYQFPT D+ V E N+ MNQ +PFAVVGS++E K+ NGK RVRQYPWG+VQ++N+NHCDF+RLREMLLR NM+DLRERTH VHYETYR+ RLIEMGF D+E MSLQETY++RRE Q KEL+QKEEE+RQMF RVKEKE LKE+++EL KFESLKK++AEEK+KLEE++R LEE+I FE+RK + EQA+QGN T+KK+K
Sbjct: 1 MTADVLKALPPDVRTLKLSGHVGFDSLPDQLVNKAISQGFVFNILCVGETGIGKSTLLETLFNQKFDFSPSNHDLTDPKLKAVTYDLKEANVKLKLTVVETCGYGDQINKENNIKPVVDYIDNQFENYLQEELKMKRSMQAFHDTRVHVCLYFIAPTGHSLKSIDLVAMKKLENKVNVIPVIAKSDTITKSELQKFKARILSEIQSNEIGIYQFPTDDEAVSETNSVMNQHIPFAVVGSSEEVKI-NGKTVRVRQYPWGSVQVENENHCDFVRLREMLLRVNMEDLRERTHGVHYETYRRQRLIEMGFRDDEKMSLQETYEKRRELQRKELQQKEEEMRQMFVQRVKEKEQVLKEAERELQTKFESLKKTHAEEKKKLEEKKRFLEEEIAAFERRKQLAEQARQGNLTMKKRK 412
BLAST of Septin-2 vs. TrEMBL
Match: A0A504YUL9 (Septin-2 OS=Fasciola gigantica OX=46835 GN=FGIG_01793 PE=3 SV=1) HSP 1 Score: 557.37 bits (1435), Expect = 0.000e+0 Identity = 293/419 (69.93%), Postives = 364/419 (86.87%), Query Frame = 1
Query: 109 VKGLANEIRTLKINGHVGFDTLPYQLVNKAVNQGFSFNILC-----------LGETGLGKSTLMETLFEQNFDFTPSTHDLPEVSLKVSNFDLKEGNVKLKLSIIESCGFGDQINKEDCVNPVISYIDGEFEKYLQEEMKIKRNLYNYHDTRVHVCLYFIAPTGHTMKSLDLVAMKKLESKVSIIPVIAKSDTITKSEMQKFKAKIMNEIQSNKINIYQFPTTDDTVRELNTQMNQLLPFAVVGSNDEAKMPNGKVSRVRQYPWGTVQIDNDNHCDFIRLREMLLRTNMDDLRERTHLVHYETYRKHRLIEMGFSDNENMSLXXXXXXXXXXXXXXXXXXXXXIRQMFFMRVKEKENQLKESDKELLAKFESLKKSNAXXXXXXXXXXXXXXXDIGNFEKRKAIVEQAKQGN-TIKKKK 1329
VK +A E+RTLK++GHVGFD+LP QLVNKAV+QGFSFNILC +GETG+GKSTL+ETLF Q FDF PS HDLP LK S F+LKEGNVKLKLS++E+CGFGDQ+NKED + PVI Y++ +FEKYLQEE+K+KR+L N+HDTR+HVCLYFIAPTGH++KSLD+VAMK LESKV++IP+IAKSDT+TK E+QKFKA+I++EIQSN+INIYQFPT D+TV ++NT+MNQ +PFAVVGS +E K+ NGK +RVRQYPWG VQ+DN++HCDF+RLREMLLR NM+DLRERTH V+YETYR+ RLIEMGF D+E MSLQETY++RRE Q KEL+QKEEE+RQ+F RVKEKE LKE+++EL AKFE+LKK++AEEK+KLE+++RILEE++ FE+RK + EQAKQGN T+KKKK
Sbjct: 5 VKAIAGEVRTLKLSGHVGFDSLPNQLVNKAVSQGFSFNILCVGKVEFNTYSWIGETGIGKSTLIETLFNQKFDFVPSLHDLPNPKLKESFFELKEGNVKLKLSVVETCGFGDQLNKEDNIKPVIDYVNSQFEKYLQEELKMKRSLQNFHDTRIHVCLYFIAPTGHSLKSLDVVAMKALESKVNVIPIIAKSDTVTKVELQKFKARILSEIQSNEINIYQFPTDDETVSDVNTKMNQHVPFAVVGSGEEIKI-NGKNARVRQYPWGAVQVDNESHCDFVRLREMLLRVNMEDLRERTHTVNYETYRRQRLIEMGFRDDEKMSLQETYEKRRELQRKELQQKEEEMRQLFVQRVKEKEQVLKEAERELQAKFEALKKNHAEEKKKLEDKKRILEEEMAAFERRKLLAEQAKQGNFTMKKKK 422
BLAST of Septin-2 vs. Ensembl Cavefish
Match: sept8a (septin-8-A [Source:NCBI gene;Acc:103023804]) HSP 1 Score: 446.432 bits (1147), Expect = 5.635e-150 Identity = 238/407 (58.48%), Postives = 314/407 (77.15%), Query Frame = 1
Query: 121 ANEIRTLKINGHVGFDTLPYQLVNKAVNQGFSFNILCLGETGLGKSTLMETLFEQNFDFTPSTHDLPEVSLKVSNFDLKEGNVKLKLSIIESCGFGDQINKEDCVNPVISYIDGEFEKYLQEEMKIKRNLYNYHDTRVHVCLYFIAPTGHTMKSLDLVAMKKLESKVSIIPVIAKSDTITKSEMQKFKAKIMNEIQSNKINIYQFPTTDDTVRELNTQMNQLLPFAVVGSNDEAKMPNGKVSRVRQYPWGTVQIDNDNHCDFIRLREMLLRTNMDDLRERTHLVHYETYRKHRLIEMGF----SDNENMSLXXXXXXXXXXXXXXXXXXXXXIRQMFFMRVKEKENQLKESDKELLAKFESLKKSNAXXXXXXXXXXXXXXXDIGNFEKRKAIVEQAKQGNTIKKKK 1329
+ E R+L + GHVGFD+LP QLV+K+V QGF FNILC+GETG+GKSTLM TLF F+ ++H V L+ +DL+E NV LKL+I+++ GFGDQINKE+ P++ YID +FE YLQEE+KIKR+L+NYHDTR+H+CLYFIAPTGH++KSLDLV MKKL+SKV+IIP+IAK+DTI+KSE+ KFK KIM+E+ SN + IYQFPT D+ V E+N+ MN LPFAVVGS +E K+ N K R RQYPWG VQ++N++HCDF++LREML+R NM+DLRE+TH HYE YR+ +L EMGF D++ SLQETY+ +R+ +L++KEEE+RQMF +VKE E++LKE ++EL KFE LK+ + EEKRK+EE+RR LEE++ F +RK E +KK K
Sbjct: 11 SEEKRSLSLGGHVGFDSLPDQLVSKSVTQGFCFNILCVGETGIGKSTLMNTLFNTTFENEEASHYQNGVYLRPRTYDLQESNVHLKLTIVDTVGFGDQINKEESYKPIVDYIDTQFENYLQEELKIKRSLFNYHDTRIHICLYFIAPTGHSLKSLDLVTMKKLDSKVNIIPIIAKADTISKSELHKFKIKIMSELVSNGVQIYQFPTDDEAVSEINSSMNAHLPFAVVGSVEEVKVGN-KTVRARQYPWGVVQVENESHCDFVKLREMLIRVNMEDLREQTHARHYELYRRCKLEEMGFKDTDPDSQPFSLQETYEAKRKEFLSDLQRKEEEMRQMFVNKVKETESELKEKERELHDKFEQLKRMHQEEKRKVEEKRRDLEEEMNAFNRRKMAAETLSLSQPLKKDK 416
BLAST of Septin-2 vs. Ensembl Cavefish
Match: sept8a (septin-8-A [Source:NCBI gene;Acc:103023804]) HSP 1 Score: 445.662 bits (1145), Expect = 7.157e-149 Identity = 238/407 (58.48%), Postives = 314/407 (77.15%), Query Frame = 1
Query: 121 ANEIRTLKINGHVGFDTLPYQLVNKAVNQGFSFNILCLGETGLGKSTLMETLFEQNFDFTPSTHDLPEVSLKVSNFDLKEGNVKLKLSIIESCGFGDQINKEDCVNPVISYIDGEFEKYLQEEMKIKRNLYNYHDTRVHVCLYFIAPTGHTMKSLDLVAMKKLESKVSIIPVIAKSDTITKSEMQKFKAKIMNEIQSNKINIYQFPTTDDTVRELNTQMNQLLPFAVVGSNDEAKMPNGKVSRVRQYPWGTVQIDNDNHCDFIRLREMLLRTNMDDLRERTHLVHYETYRKHRLIEMGF----SDNENMSLXXXXXXXXXXXXXXXXXXXXXIRQMFFMRVKEKENQLKESDKELLAKFESLKKSNAXXXXXXXXXXXXXXXDIGNFEKRKAIVEQAKQGNTIKKKK 1329
+ E R+L + GHVGFD+LP QLV+K+V QGF FNILC+GETG+GKSTLM TLF F+ ++H V L+ +DL+E NV LKL+I+++ GFGDQINKE+ P++ YID +FE YLQEE+KIKR+L+NYHDTR+H+CLYFIAPTGH++KSLDLV MKKL+SKV+IIP+IAK+DTI+KSE+ KFK KIM+E+ SN + IYQFPT D+ V E+N+ MN LPFAVVGS +E K+ N K R RQYPWG VQ++N++HCDF++LREML+R NM+DLRE+TH HYE YR+ +L EMGF D++ SLQETY+ +R+ +L++KEEE+RQMF +VKE E++LKE ++EL KFE LK+ + EEKRK+EE+RR LEE++ F +RK E +KK K
Sbjct: 11 SEEKRSLSLGGHVGFDSLPDQLVSKSVTQGFCFNILCVGETGIGKSTLMNTLFNTTFENEEASHYQNGVYLRPRTYDLQESNVHLKLTIVDTVGFGDQINKEESYKPIVDYIDTQFENYLQEELKIKRSLFNYHDTRIHICLYFIAPTGHSLKSLDLVTMKKLDSKVNIIPIIAKADTISKSELHKFKIKIMSELVSNGVQIYQFPTDDEAVSEINSSMNAHLPFAVVGSVEEVKVGN-KTVRARQYPWGVVQVENESHCDFVKLREMLIRVNMEDLREQTHARHYELYRRCKLEEMGFKDTDPDSQPFSLQETYEAKRKEFLSDLQRKEEEMRQMFVNKVKETESELKEKERELHDKFEQLKRMHQEEKRKVEEKRRDLEEEMNAFNRRKMAAETLSLSQPLKKDK 416
BLAST of Septin-2 vs. Ensembl Cavefish
Match: sept8a (septin-8-A [Source:NCBI gene;Acc:103023804]) HSP 1 Score: 442.195 bits (1136), Expect = 1.884e-148 Identity = 235/393 (59.80%), Postives = 309/393 (78.63%), Query Frame = 1
Query: 127 EIRTLKINGHVGFDTLPYQLVNKAVNQGFSFNILCLGETGLGKSTLMETLFEQNFDFTPSTHDLPEVSLKVSNFDLKEGNVKLKLSIIESCGFGDQINKEDCVNPVISYIDGEFEKYLQEEMKIKRNLYNYHDTRVHVCLYFIAPTGHTMKSLDLVAMKKLESKVSIIPVIAKSDTITKSEMQKFKAKIMNEIQSNKINIYQFPTTDDTVRELNTQMNQLLPFAVVGSNDEAKMPNGKVSRVRQYPWGTVQIDNDNHCDFIRLREMLLRTNMDDLRERTHLVHYETYRKHRLIEMGF----SDNENMSLXXXXXXXXXXXXXXXXXXXXXIRQMFFMRVKEKENQLKESDKELLAKFESLKKSNAXXXXXXXXXXXXXXXDIGNFEKRKAIVE 1293
E R+L + GHVGFD+LP QLV+K+V QGF FNILC+GETG+GKSTLM TLF F+ ++H V L+ +DL+E NV LKL+I+++ GFGDQINKE+ P++ YID +FE YLQEE+KIKR+L+NYHDTR+H+CLYFIAPTGH++KSLDLV MKKL+SKV+IIP+IAK+DTI+KSE+ KFK KIM+E+ SN + IYQFPT D+ V E+N+ MN LPFAVVGS +E K+ N K R RQYPWG VQ++N++HCDF++LREML+R NM+DLRE+TH HYE YR+ +L EMGF D++ SLQETY+ +R+ +L++KEEE+RQMF +VKE E++LKE ++EL KFE LK+ + EEKRK+EE+RR LEE++ F +RK E
Sbjct: 10 EKRSLSLGGHVGFDSLPDQLVSKSVTQGFCFNILCVGETGIGKSTLMNTLFNTTFENEEASHYQNGVYLRPRTYDLQESNVHLKLTIVDTVGFGDQINKEESYKPIVDYIDTQFENYLQEELKIKRSLFNYHDTRIHICLYFIAPTGHSLKSLDLVTMKKLDSKVNIIPIIAKADTISKSELHKFKIKIMSELVSNGVQIYQFPTDDEAVSEINSSMNAHLPFAVVGSVEEVKVGN-KTVRARQYPWGVVQVENESHCDFVKLREMLIRVNMEDLREQTHARHYELYRRCKLEEMGFKDTDPDSQPFSLQETYEAKRKEFLSDLQRKEEEMRQMFVNKVKETESELKEKERELHDKFEQLKRMHQEEKRKVEEKRRDLEEEMNAFNRRKMAAE 401
BLAST of Septin-2 vs. Ensembl Cavefish
Match: sept8b (septin-8-A [Source:NCBI gene;Acc:103040455]) HSP 1 Score: 439.113 bits (1128), Expect = 4.288e-147 Identity = 230/416 (55.29%), Postives = 316/416 (75.96%), Query Frame = 1
Query: 115 GLANEIRTLKINGHVGFDTLPYQLVNKAVNQGFSFNILCLGETGLGKSTLMETLFEQNFDFTPSTHDLPEVSLKVSNFDLKEGNVKLKLSIIESCGFGDQINKEDCVNPVISYIDGEFEKYLQEEMKIKRNLYNYHDTRVHVCLYFIAPTGHTMKSLDLVAMKKLESKVSIIPVIAKSDTITKSEMQKFKAKIMNEIQSNKINIYQFPTTDDTVRELNTQMNQLLPFAVVGSNDEAKMPNGKVSRVRQYPWGTVQIDNDNHCDFIRLREMLLRTNMDDLRERTHLVHYETYRKHRLIEMGF----SDNENMSLXXXXXXXXXXXXXXXXXXXXXIRQMFFMRVKEKENQLKESDKELLAKFESLKKSNAXXXXXXXXXXXXXXXDIGNFEKRKAIVE-------QAKQGNTIKKKK 1329
+ E RTL + GHVGFD+LP QLV+K+V+QGF FNILC+GETG+GKSTLM TLF F+ ++H V L+ ++L+E NV LKL+I+++ GFGDQINKE+ P++ YID +FE +LQEE+KIKR+L+NYHDTR+H+CLYFI+PTGH+++SLDLV MKKL+SKV++IP+IAK+DTI+K E+ KFK K+M+E+ SN + IYQFPT D+ V E+N+ MN LPFAVVGS++E K+ N K+ R RQ+PWG VQ++N++HCDF++LREMLLR NM+DLRE+TH HYE YR+ +L EMGF +D + SLQ+ Y +R EL++ EE++RQMF +VKE E +LKE ++EL +FE LK+ + EEKR LE++RR LEE++ +F +RK E Q+ +TIKK+K
Sbjct: 10 SVTEEKRTLTLCGHVGFDSLPDQLVSKSVSQGFCFNILCVGETGIGKSTLMNTLFNTTFENEEASHHQNTVYLRPRTYNLQESNVDLKLTIVDTVGFGDQINKEESYKPILDYIDNQFENFLQEELKIKRSLHNYHDTRIHICLYFISPTGHSLRSLDLVTMKKLDSKVNLIPLIAKADTISKCELHKFKIKVMSELVSNGVQIYQFPTDDEAVTEINSTMNAHLPFAVVGSSEEVKVGN-KMVRARQFPWGVVQVENESHCDFVKLREMLLRVNMEDLREQTHARHYELYRRCKLEEMGFKDSNTDAQPFSLQDVYVAKRREFVAELQRSEEDMRQMFVNKVKETEAELKERERELHERFEQLKRLHQEEKRSLEQKRRELEEEMNSFSRRKVAAEALQACTLQSSITHTIKKEK 424
BLAST of Septin-2 vs. Ensembl Cavefish
Match: sept10 (septin-10 [Source:NCBI gene;Acc:103044988]) HSP 1 Score: 438.728 bits (1127), Expect = 6.494e-147 Identity = 225/391 (57.54%), Postives = 310/391 (79.28%), Query Frame = 1
Query: 133 RTLKINGHVGFDTLPYQLVNKAVNQGFSFNILCLGETGLGKSTLMETLFEQNFDFTPSTHDLPEVSLKVSNFDLKEGNVKLKLSIIESCGFGDQINKEDCVNPVISYIDGEFEKYLQEEMKIKRNLYNYHDTRVHVCLYFIAPTGHTMKSLDLVAMKKLESKVSIIPVIAKSDTITKSEMQKFKAKIMNEIQSNKINIYQFPTTDDTVRELNTQMNQLLPFAVVGSNDEAKMPNGKVSRVRQYPWGTVQIDNDNHCDFIRLREMLLRTNMDDLRERTHLVHYETYRKHRLIEMGFSDN----ENMSLXXXXXXXXXXXXXXXXXXXXXIRQMFFMRVKEKENQLKESDKELLAKFESLKKSNAXXXXXXXXXXXXXXXDIGNFEKRKAIVE 1293
R+L ++GHVGFD+LP QLVNK+ NQGF FNILC+GETG+GKSTLM+TLF NF+ S+H P+V L+ +DL+E NV+LKL+++ + GFGDQ+NK++ ++ YID +FE +LQEE+KI+R+L+N+HD+R+H CLYFIAP+GH++KSLDLV MKKL+SKV+IIPVIAK+DTI+KSE+ KFK KIM+E+ SN + IYQFP D+TV +NT MN LPFAVVGS +E + N K+ + RQYPWG VQ++N++HCDF++LREML+ NM+DLRE+TH HYE YR+ +L EMGF D + +SLQETY+ +R+ +L+++EEE++Q F +VKEKE +LKES+++L AKF+ LK+ +AEEK LEE++R LEE+I +F R+A E
Sbjct: 15 RSLTLSGHVGFDSLPDQLVNKSTNQGFCFNILCIGETGIGKSTLMDTLFNTNFENFESSHFEPQVKLRAQTYDLQESNVRLKLTVVNTVGFGDQMNKKESYQHIVDYIDTQFESFLQEELKIRRSLHNFHDSRIHACLYFIAPSGHSLKSLDLVTMKKLDSKVNIIPVIAKADTISKSELHKFKMKIMSELVSNGVQIYQFPIDDETVATINTTMNGHLPFAVVGSTEEVNVGN-KMVKARQYPWGVVQVENESHCDFVKLREMLICINMEDLREQTHTRHYELYRRCKLEEMGFKDTNPECQPISLQETYEAKRKEFQADLQRQEEEMKQSFVQKVKEKEGELKESERQLQAKFDQLKRQHAEEKSVLEEKKRALEEEIFSFSNRRAAAE 404
BLAST of Septin-2 vs. Ensembl Sea Lamprey
Match: SEPTIN9 (septin 9 [Source:HGNC Symbol;Acc:HGNC:7323]) HSP 1 Score: 248.44 bits (633), Expect = 6.088e-76 Identity = 139/319 (43.57%), Postives = 206/319 (64.58%), Query Frame = 1
Query: 94 MTTEVVK---GLANEIRTLKIN----GHVGFDTLPYQLVNKAVNQGFSFNILCLGETGLGKSTLMETLFEQNFD---FTPSTHD-LPE-VSLKVSNFDLKEGNVKLKLSIIESCGFGDQINKEDCVNPVISYIDGEFEKYLQEEMKIKRNLYNYHDTRVHVCLYFIAPTGHTMKSLDLVAMKKLESKVSIIPVIAKSDTITKSEMQKFKAKIMNEIQSNKINIYQFPT--TDDTVRELNTQMNQLLPFAVVGSNDEAKMPNGKVSRVRQYPWGTVQIDNDNHCDFIRLREMLLRTNMDDLRERTHLVHYETYRKHRLIE 1008
MTTE G+A +K N G+VG D + Q+ KA+ QGF FNI+ +G++GLGKSTL+ TLF+ TP+ + +P+ V +K + ++E VK+KL++I++ GFGDQIN +C PV+ YI+ ++EKYL EE+ I R D+RVH C+YFI TGH+++ LD+ MK+L V+I+PVIAKSDT+T E Q FK KI ++++ I+IY D+ R +N ++ +L+PFAVVGS D+ + NG+ + R+ WG ++I+N HC+F +LRE+L+R++ DL+E T VHYE YR RL E
Sbjct: 19 MTTETPGQDGGVARPPTRVKPNLDAFGYVGIDAVLEQMRRKAMKQGFEFNIMVVGQSGLGKSTLVNTLFKSPVSRKSCTPNHEEKIPKTVEIKSVSHVIEEKGVKMKLTVIDTPGFGDQINNNNCWEPVLKYINDQYEKYLAEEVNITRKKV-IPDSRVHCCIYFIPATGHSLRLLDIEFMKRLGKVVNIVPVIAKSDTLTLEERQAFKKKIREQLETQGISIYPHKEHDEDEEDRSVNNKIRELMPFAVVGS-DKDYLVNGRKTLGRKTKWGIIEIENVAHCEFSQLRELLIRSHTQDLKEVTSCVHYEGYRVLRLSE 335
BLAST of Septin-2 vs. Ensembl Sea Lamprey
Match: SEPTIN7 (septin 7 [Source:HGNC Symbol;Acc:HGNC:1717]) HSP 1 Score: 248.054 bits (632), Expect = 1.669e-74 Identity = 128/306 (41.83%), Postives = 194/306 (63.40%), Query Frame = 1
Query: 130 IRTLKINGHVGFDTLPYQLVNKAVNQGFSFNILCLGETGLGKSTLMETLFEQNF---DFTPSTHDLPE-VSLKVSNFDLKEGNVKLKLSIIESCGFGDQINKEDCVNPVISYIDGEFEKYLQEEMKIKRNLYNYHDTRVHVCLYFIAPTGHTMKSLDLVAMKKLESKVSIIPVIAKSDTITKSEMQKFKAKIMNEIQSNKINIYQFPTT-DDTVRELNTQMNQLLPFAVVGSNDEAKMPNGKVSRVRQYPWGTVQIDNDNHCDFIRLREMLLRTNMDDLRERTHLVHYETYRKHRLIEMGFSDNEN 1032
++T + G+VGF LP Q+ KA +GF F ++ +GE+G+GKSTL+ ++F+ + +F T + + V ++ S ++E V L L+I+++ G+GD IN +CV PVI +ID +FE YL E ++ R D+RVH CLYFIAP+GH +K+LD+ MK+L +KV+IIP++AK+D +E FK +IM +I N I IYQF T D+ +L ++ + LP AV+GSN + G+ R YPWG ++DN HCDF LR ML+RT+M DL++ T+ VHYE +R +L + + EN
Sbjct: 25 LQTKPMEGYVGFANLPNQIYRKAAKRGFEFTLMVVGESGVGKSTLINSMFKTDLYSEEFPGPTKRIQKTVKVEQSKVVIREEGVHLTLTIVDTPGYGDFINNSECVQPVIDHIDSQFEDYLNAESRVNRR--PMPDSRVHACLYFIAPSGHGLKALDIEFMKRLHNKVNIIPLVAKADAFLPTECCAFKKQIMKDIHDNNIKIYQFTDTHDEEDNKLLNKIKERLPLAVIGSNVVVDV-GGRRVWGRHYPWGVAEVDNVEHCDFTTLRRMLIRTHMQDLKDVTNNVHYENFRSCKLAALTGNVAEN 327
BLAST of Septin-2 vs. Ensembl Sea Lamprey
Match: zgc:162239 (zgc:162239 [Source:ZFIN;Acc:ZDB-GENE-070424-28]) HSP 1 Score: 239.965 bits (611), Expect = 4.212e-72 Identity = 120/293 (40.96%), Postives = 179/293 (61.09%), Query Frame = 1
Query: 154 HVGFDTLPYQLVNKAVNQGFSFNILCLGETGLGKSTLMETLFEQNFDFTPSTHD---LPEVSLKVSN-------FDLKEGNVKLKLSIIESCGFGDQINKEDCVNPVISYIDGEFEKYLQEEMKIKRNLYNYHDTRVHVCLYFIAPTGHTMKSLDLVAMKKLESKVSIIPVIAKSDTITKSEMQKFKAKIMNEIQSNKINIYQFPTT----DDTVRELNTQMNQLLPFAVVGSNDEAKMPNGKVSRVRQYPWGTVQIDNDNHCDFIRLREMLLRTNMDDLRERTHLVHYETYR 990
+VGF TLP Q+ K+V +GF F ++ GE+GLGKSTL+ +LF T HD LP + +++E V+L+LS++++ GF D I+ +C PV+ Y++ +FE Y +EE + R N DTRVH CLYFI+P GH +K LD+ MK L +KV+I+PVIAK+DT+T E + K ++ E+ N I IYQFP DD + + ++ +PFAV+G + + +G+ R R YPWG ++D+ HCD +LR ML+RT+M DL++ T +HYE +R
Sbjct: 24 YVGFATLPNQVHRKSVKKGFEFTLMVAGESGLGKSTLINSLF-----LTDLYHDRVLLPADGKRCDTTEILRRTLEIEEKGVRLRLSLVDTPGFADAIDNTECWQPVVEYVEEQFESYFREESGLDRK--NLQDTRVHCCLYFISPYGHGLKPLDVEFMKALHNKVNIVPVIAKADTLTMRERETLKRRVQEELSENDIKIYQFPECDSDEDDEFKRQDEELKASIPFAVIGGSAVVEA-SGRRVRGRLYPWGIAEVDSSEHCDLAKLRTMLIRTHMQDLKDVTRDLHYEEHR 308
BLAST of Septin-2 vs. Ensembl Sea Lamprey
Match: SEPTIN9 (septin 9 [Source:HGNC Symbol;Acc:HGNC:7323]) HSP 1 Score: 210.305 bits (534), Expect = 2.496e-62 Identity = 110/266 (41.35%), Postives = 173/266 (65.04%), Query Frame = 1
Query: 235 GETGLGKSTLMETLFEQNFDFTPSTHDLPEVSLKVSNFD-----LKEGNVKLKLSIIESCGFGDQINKEDCVNPVISYIDGEFEKYLQEEMKIKRNLYNYHDTRVHVCLYFIAPTGHTMKSLDLVAMKKLESKVSIIPVIAKSDTITKSEMQKFKAKIMNEIQSNKINIY---QFPTTDDTVRELNTQMNQLLPFAVVGSNDEAKMPNGKVSRVRQYPWGTVQIDNDNHCDFIRLREMLLRTNMDDLRERTHLVHYETYRKHRLIE 1008
G++GLGKSTL+ TLF+ T + E LK ++E VK+KL++I++ GFGDQIN E+C P++ YI ++EKYL+EE++I R + DTRVH C+Y I P+GH+++ LD+ M+ L VS++PVI K+DT+T E F+ +I ++ ++ I++Y +F D+ R N ++ + +PFAVVGS+ E + NG+ R+ WG V+++N NHC+F LR++L+R++M+DL++ TH + YETYR RL E
Sbjct: 1 GQSGLGKSTLVNTLFKSRVSRKSCTPNYQERILKTVEIQSVSHVIEERGVKMKLTVIDTPGFGDQINNENCWEPILKYIGEQYEKYLREEVRITRKRH-IPDTRVHCCIYCIPPSGHSLRPLDVEFMQHLSKVVSVVPVITKADTLTLEERHLFRQRIQADLVAHGIDVYPQREF-DEDEQGRLENAEVREKIPFAVVGSDREYQ-ENGRRVLGRKTRWGLVEVENINHCEFALLRDLLIRSHMEDLKDVTHSILYETYRVRRLNE 263
BLAST of Septin-2 vs. Ensembl Sea Lamprey
Match: SEPTIN7 (septin 7 [Source:HGNC Symbol;Acc:HGNC:1717]) HSP 1 Score: 184.496 bits (467), Expect = 9.336e-54 Identity = 93/215 (43.26%), Postives = 138/215 (64.19%), Query Frame = 1
Query: 145 INGHVGFDTLPYQLVNKAVNQGFSFNILCLGETGLGKSTLMETLFEQNFDFT----PSTHDLPEVSLKVSNFDLKEGNVKLKLSIIESCGFGDQINKEDCVNPVISYIDGEFEKYLQEEMKIKRNLYNYHDTRVHVCLYFIAPTGHTMKSLDLVAMKKLESKVSIIPVIAKSDTITKSEMQKFKAKIMNEIQSNKINIYQFPTTDDTVRELNTQM 777
+ G+VGF LP Q+ K+V +GF F ++ +GE+GLGKSTL+ +LF + + PS + ++ S LKEG V+L L+I+++ GFGD ++ C +I YID + E YL E ++ R L D+RVH CLYFI P+GH +K LD+ MK+L KV+IIP+IAK+D++T E Q+FK IM EI +KI IY+FP +D +L+ ++
Sbjct: 13 LEGYVGFANLPNQVYRKSVKRGFEFTLMVVGESGLGKSTLINSLFLTDLYASEYPGPSQRVRKTLQVEQSKVVLKEGGVQLTLTIVDTPGFGDAVDNSSCWQSIIDYIDSKCEDYLNAEARVNRRLMP--DSRVHCCLYFIFPSGHQLKPLDIEFMKRLHDKVNIIPLIAKADSLTTEECQQFKKTIMKEILEHKIKIYEFPDVEDDDEKLSKKV 225
BLAST of Septin-2 vs. Ensembl Yeast
Match: CDC3 (Component of the septin ring that is required for cytokinesis; septins are GTP-binding proteins that assemble with other septins into rod-like complexes that can associate with other rods to form filament polymers; septin rings at the mother-bud neck act as scaffolds for recruiting factors needed for cell division and as barriers to prevent diffusion of specific proteins between mother and daughter cells [Source:SGD;Acc:S000004306]) HSP 1 Score: 237.269 bits (604), Expect = 8.292e-70 Identity = 143/387 (36.95%), Postives = 224/387 (57.88%), Query Frame = 1
Query: 142 KINGHVGFDTLPYQLVNKAVNQGFSFNILCLGETGLGKSTLMETLF-----EQNF--DF-------------------TPSTHDLPEVSLKVSNFDLKEGNVKLKLSIIESCGFGDQINKED-CVNPVISYIDGEFEKYLQEEMKIKRNLYNYHDTRVHVCLYFIAPTGHTMKSLDLVAMKKLESKVSIIPVIAKSDTITKSEMQKFKAKIMNEIQSNKINIYQFP--TTDDTV-RELNTQMNQLLPFAVVGSNDEAKMPNGKVSRVRQYPWGTVQIDNDNHCDFIRLREMLLRTNMDDLRERTHLVHYETYRKHRLIEMGFSDNENM----SLXXXXXXXXXXXXXXXXXXXXXIRQMFFMRVKEKENQLKESDKELLAKFESLKK 1200
+ING+VGF LP Q +++ GFSFN+LC+G G+GK+TLM+TLF E N D+ S +V +K ++E VKL L++I++ GFGD +N + +P+I ID F++YL E KI R+ N D R+H CLYFI PTGH +K LDL M+ + K ++IPVIAKSD +T E+ FK IMN++ + I +++ P + DD L+ ++ LP+AV+GSND + +G R R YPWG +++DNDNH DF L+ +L++ M++L+ERT + YE YR +L ++G + ++ Q+ + +L + E E++ +F +V EKE +L++S+ EL A+ + +K+
Sbjct: 95 QINGYVGFANLPKQWHRRSIKNGFSFNLLCVGPDGIGKTTLMKTLFNNDDIEANLVKDYEEELANDQEEEEGQGEGHENQSQEQRHKVKIKSYESVIEENGVKLNLNVIDTEGFGDFLNNDQKSWDPIIKEIDSRFDQYLDAENKINRHSIN--DKRIHACLYFIEPTGHYLKPLDLKFMQSVYEKCNLIPVIAKSDILTDEEILSFKKTIMNQLIQSNIELFKPPIYSNDDAENSHLSERLFSSLPYAVIGSNDIVENYSGNQVRGRSYPWGVIEVDNDNHSDFNLLKNLLIKQFMEELKERTSKILYENYRSSKLAKLGIKQDNSVFKEFDPISKQQEEKTLHEAKLAKLEIEMKTVFQQKVSEKEKKLQKSETELFARHKEMKE 479
BLAST of Septin-2 vs. Ensembl Yeast
Match: CDC10 (Component of the septin ring, required for cytokinesis; septins are GTP-binding proteins that assemble into rod-like hetero-oligomers that can associate to form filaments; septin rings at the mother-bud neck act as scaffolds for recruiting cell division factors and as barriers to prevent diffusion of specific proteins between mother and daughter cells; N-terminus interacts with phosphatidylinositol-4,5-bisphosphate; protein abundance increases under DNA damage stress [Source:SGD;Acc:S000000595]) HSP 1 Score: 211.075 bits (536), Expect = 2.559e-62 Identity = 112/304 (36.84%), Postives = 181/304 (59.54%), Query Frame = 1
Query: 151 GHVGFDTLPYQLVNKAVNQGFSFNILCLGETGLGKSTLMETLFEQNFDFTPSTHDLPEV------SLKVSNFDLKEGNVKLKLSIIESCGFGDQINKEDCVNPVISYIDGEFEKYLQEEMKIKRNLYNYHDTRVHVCLYFIAPTGHTMKSLDLVAMKKLESKVSIIPVIAKSDTITKSEMQKFKAKIMNEIQSNKINIYQFPT--TDDTVRELNTQMNQLLPFAVVGSNDEAKMPNGKVSRVRQYPWGTVQIDNDNHCDFIRLREMLLRTNMDDLRERTHLVHYETYRKHRLIEMGFSDNENMS 1038
+VGFDT+ Q+ ++ + +GF FNI+ +G++GLGKSTL+ TLF + + + D+ + +K+S L E V+L +++I++ GFGD I+ P++ YI + +YL++E+ +R + DTRVH LYF+ P G + LD+ A+K+L ++IPVI KSDT+T E +F+ I NE + IY + + D ELN + ++PFAVVGS +E ++ NG+ R R+ W + +++ N CDF+ LRE L+RT++ DL E T +HYE +R +LI + + N S
Sbjct: 11 SYVGFDTITNQIEHRLLKKGFQFNIMVVGQSGLGKSTLINTLFASHLIDSATGDDISALPVTKTTEMKISTHTLVEDRVRLNINVIDTPGFGDFIDNSKAWEPIVKYIKEQHSQYLRKELTAQRERF-ITDTRVHAILYFLQPNGKELSRLDVEALKRLTEIANVIPVIGKSDTLTLDERTEFRELIQNEFEKYNFKIYPYDSEELTDEELELNRSVRSIIPFAVVGSENEIEI-NGETFRGRKTRWSAINVEDINQCDFVYLREFLIRTHLQDLIETTSYIHYEGFRARQLIALKENANSRSS 312
BLAST of Septin-2 vs. Ensembl Yeast
Match: CDC12 (Component of the septin ring that is required for cytokinesis; septins are GTP-binding proteins that assemble into rod-like hetero-oligomers that can associate with other rods to form filaments; septin rings at the mother-bud neck act as scaffolds for recruiting cell division factors and as barriers to prevent diffusion of specific proteins between mother and daughter cells [Source:SGD;Acc:S000001149]) HSP 1 Score: 199.519 bits (506), Expect = 3.848e-57 Identity = 125/364 (34.34%), Postives = 210/364 (57.69%), Query Frame = 1
Query: 160 GFDTLP---YQLVNKAVNQGFSFNILCLGETGLGKSTLMETLFEQNFDFTPSTHDLPE-----VSLKVSNFDLKEGNVKLKLSIIESCGFGDQINKEDCVNPVISYIDGEFEKYLQEEMKIKRNLYNYHDTRVHVCLYFIAPTGHTMKSLDLVAMKKLESKVSIIPVIAKSDTITKSEMQKFKAKIMNEIQSNKINIYQFP-------------TTDDTVRELNTQMNQLLPFAVVGSNDEAKMPNGKVSRV--RQYPWGTVQIDNDNHCDFIRLREMLLRTNMDDLRERTHLVHYETYRKHRL--IEMGFSDNENMSLXXXXXXXXXXXXXXXXXXXXXIRQMFFMRVKEKENQLKESDKELL 1176
G LP Y++VN+ +G +F ++ GE+GLGK+T + TLF+ E V + ++ L+E + +L++++I++ GFGD +N P++ +ID + + Y+++E + R D RVH LYFI PTGH +K +D+ MK+L ++ ++IPVIAK+DT+T E+Q+FK++I I++ +I I+ P D E Q+ + +PFA+VGS E K NG+ ++V R+YPWG V+I+ND+HCDF +LR +LLRT + DL T +HYETYR+ RL E NE+ +L R+ + K++E +++ F +VK +E + ++ ++ ++
Sbjct: 16 GISNLPNQRYKIVNE---EGGTFTVMLCGESGLGKTTFINTLFQTVLKRADGQQHRQEPIRKTVEIDITRALLEEKHFELRVNVIDTPGFGDNVNNNKAWQPLVDFIDDQHDSYMRQEQQPYRT--KKFDLRVHAVLYFIRPTGHGLKPIDIETMKRLSTRANLIPVIAKADTLTAQELQQFKSRIRQVIEAQEIRIFTPPLDADSKEDAKSGSNPDSAAVEHARQLIEAMPFAIVGS--EKKFDNGQGTQVVARKYPWGLVEIENDSHCDFRKLRALLLRTYLLDLISTTQEMHYETYRRLRLEGHENTGEGNEDFTLPAIAPARKLSHNPRYKEEENALKKYFTDQVKAEEQRFRQWEQNIV 372
BLAST of Septin-2 vs. Ensembl Yeast
Match: CDC11 (Component of the septin ring that is required for cytokinesis; present at the ends of rod-like septin hetero-oligomers; C-terminal extension is important for recruitment of Bni5p to the mother-bud neck, which in turn is required for Myo1p recruitment and cytokinesis; septin rings at the mother-bud neck act as scaffolds for recruiting cell division factors and as barriers to prevent diffusion of specific proteins between mother and daughter cells [Source:SGD;Acc:S000003837]) HSP 1 Score: 184.111 bits (466), Expect = 1.400e-51 Identity = 103/284 (36.27%), Postives = 170/284 (59.86%), Query Frame = 1
Query: 193 KAVNQGFSFNILCLGETGLGKSTLMETLFEQNFDFTPSTHDLP-------EVSLKVSNFDLKEG-NVKLKLSIIESCGFGDQINKEDCVNPVISYIDGEFEKYLQEEMKIKRNLYNYHDTRVHVCLYFIAPTGHTMKSLDLVAMKKLESKVSIIPVIAKSDTITKSEMQKFKAKIMNEIQSNKINIYQFPTTDDTVR----ELNTQMNQLLPFAVVGSNDEAKMPNGKVS--RVRQYPWGTVQIDNDNHCDFIRLREMLLRTNMDDLRERTHLVHYETYRKHRL 1002
K + +G +F ++ +G++G G+ST + TL Q T +T LP ++ L+ +L++ VK++L+II++ GFGD ++ + YI ++++ L EE +++RN + D RVH CLY I PTGH +K +D+ +++L S V+IIPVI+KSD++T+ E++ K IM +I + IY FP +D + E N + LLPFA++GSN+ +M G V R R+YPWG + +++ + DF+ LR LL +++ DL+ TH + YE YR L
Sbjct: 15 KHLKRGITFTVMIVGQSGSGRSTFINTLCGQQVVDTSTTILLPTDTSTEIDLQLREETVELEDDEGVKIQLNIIDTPGFGDSLDNSPSFEIISDYIRHQYDEILLEESRVRRN-PRFKDGRVHCCLYLINPTGHGLKEIDVEFIRQLGSLVNIIPVISKSDSLTRDELKLNKKLIMEDIDRWNLPIYNFPFDEDEISDEDYETNMYLRTLLPFAIIGSNEVYEM-GGDVGTIRGRKYPWGILDVEDSSISDFVILRNALLISHLHDLKNYTHEILYERYRTEAL 296
BLAST of Septin-2 vs. Ensembl Yeast
Match: SPR3 (Sporulation-specific homolog of the CDC3/10/11/12 family of genes; septin protein involved in sporulation; regulated by ABFI; the yeast CDC3/10/11/12 family is a family of bud neck microfilament genes [Source:SGD;Acc:S000003291]) HSP 1 Score: 151.369 bits (381), Expect = 2.408e-39 Identity = 97/296 (32.77%), Postives = 153/296 (51.69%), Query Frame = 1
Query: 121 ANEIRTLKINGHVGFDTLPYQLVNKAVNQGFSFNILCLGETGLGKSTLMETLFEQNFDFTPSTHDLPEVSLKVSNFDLKEGN-VKLKLSIIESCGFGDQINKEDCVNPVISYIDGEFEKYL-QEEMKIKRNLYNYHDTRVHVCLYFIAPTGHTMKSLDLVAMKKLESKVSIIPVIAKSDTITKSEMQKFKAKIMNEIQSNKINIYQFPTTDDTVRELNTQMNQLLPFAVVGSNDEAKMPNGKVSRVRQYPWGTVQIDNDNHCDFIRLREMLLRTNMDDLRERTHLVHYETYRKHRL 1002
A EI T +G LP Q G F ++ G++GLGK+T + +LF + + P + K + EG+ L ++I++ GFG+ ++ +++YID E Y+ QEE + + D RVH CLYF+ P+ + +LD+V MKKL +V++IPVIAKSD +TK E++ FK ++ I+ I + F D V + Q PF+++ SN+ G+ + RQY WG V I+N+ +CDF L++ + N+ DL E T +YE R L
Sbjct: 78 AQEINTNSHGQDIGIKNLPRQRELLNAKNGIDFTLMVAGQSGLGKTTFINSLFSTSLIDDDIKENKPIIRYK----SIVEGDGTHLNFNVIDTPGFGNNMDNAFTWRTMVNYIDEEIRSYIFQEEQPDRTKMV---DNRVHCCLYFLRPSNKGIDTLDVVTMKKLAKRVNLIPVIAKSDLLTKEELKNFKTQVREIIRVQDIPVCFF--FGDEVLNATQDIFQKYPFSIIASNEYIFNEKGEKVKGRQYKWGAVDIENEKYCDFKILQKTIFDWNLIDLVESTE-DYYEKCRSEML 363
BLAST of Septin-2 vs. Ensembl Nematostella
Match: EDO37950 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SE59]) HSP 1 Score: 419.853 bits (1078), Expect = 6.524e-141 Identity = 201/367 (54.77%), Postives = 289/367 (78.75%), Query Frame = 1
Query: 85 LKNMTTEVVKGLANEIRTLKINGHVGFDTLPYQLVNKAVNQGFSFNILCLGETGLGKSTLMETLFEQNFDFTPSTHDLPEVSLKVSNFDLKEGNVKLKLSIIESCGFGDQINKEDCVNPVISYIDGEFEKYLQEEMKIKRNLYNYHDTRVHVCLYFIAPTGHTMKSLDLVAMKKLESKVSIIPVIAKSDTITKSEMQKFKAKIMNEIQSNKINIYQFPTTDDTVRELNTQMNQLLPFAVVGSNDEAKMPNGKVSRVRQYPWGTVQIDNDNHCDFIRLREMLLRTNMDDLRERTHLVHYETYRKHRLIEMGFSD----NENMSLXXXXXXXXXXXXXXXXXXXXXIRQMFFMRVKEKENQLKESDKEL 1173
+ + T+ + L + R L++ GHVGFD+LP QLVNK+VN+GF+FNILC+GETG+GKSTLM+TLF+ F+ P +H LP V ++ +DL E NV LKL+I+++ G+GDQINKED + +++YID +F+ YL +E+KIKR + +HDTR+H CLYFI+PTGH++KSLDLV MK+L+ KV+IIP+IAK+DTI KSE+++FK KIM+E++SN + IY+FP D+TV E+N+ MN +PFAVVGS +E M N SR R YPWGTV+++N+NHCDF++LREML+RTNM L ++TH VHYE +R+++L EMGF+D N++ SLQETY++RR+ + + KEE++RQ F +VK+KEN+LK++++E+
Sbjct: 1 MASAVTDYCRSLGADGRQLRLAGHVGFDSLPDQLVNKSVNRGFAFNILCIGETGIGKSTLMDTLFQTTFEGQPHSHHLPGVQIEHHTYDLNESNVMLKLTIVDTVGYGDQINKEDSSSSIVNYIDQQFDTYLHQELKIKRTMDTFHDTRIHACLYFISPTGHSLKSLDLVCMKQLDKKVNIIPIIAKADTIAKSELKQFKQKIMDELESNGVEIYRFPVDDETVAEMNSTMNNEIPFAVVGSREEV-MVNKTKSRARVYPWGTVEVENENHCDFVKLREMLIRTNMQSLIDKTHTVHYELFRRNKLEEMGFNDGDANNKSHSLQETYEERRKEYMSQFQDKEEKMRQRFVQKVKDKENELKKAEQEV 366
BLAST of Septin-2 vs. Ensembl Nematostella
Match: EDO34522 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SP25]) HSP 1 Score: 276.944 bits (707), Expect = 4.318e-85 Identity = 138/297 (46.46%), Postives = 204/297 (68.69%), Query Frame = 1
Query: 145 INGHVGFDTLPYQLVNKAVNQGFSFNILCLGETGLGKSTLMETLFEQNFDFTPSTH-DLPE-----VSLKVSNFDLKEGNVKLKLSIIESCGFGDQINKEDCVNPVISYIDGEFEKYLQEEMKIKRNLYNYHDTRVHVCLYFIAPTGHTMKSLDLVAMKKLESKVSIIPVIAKSDTITKSEMQKFKAKIMNEIQSNKINIYQFPT-TDDTVRELNT-QMNQLLPFAVVGSNDEAKMPNGKVSRVRQYPWGTVQIDNDNHCDFIRLREMLLRTNMDDLRERTHLVHYETYRKHRLIEM 1011
+ G+VGF LP Q+ K+V +GF F ++ +GE+GLGKSTL+ +LF + +TPS++ + E V +K +LKEG V+L+L+++++ GFGD ++ DC PVI YID +FE++L E +++R+ + D RVH CLYFI+PTGH++K LD+ MKKL +KV+I+PVI+K+DT+T E +FK +I+ EI+ N I+IY+FP + EL+ M +PFAVVGSN ++ NGK R R YPWG V+++N HCDF+ LR ML+RT+M DL++ T+ HYE YR +L M
Sbjct: 1 MEGYVGFANLPNQVFRKSVKKGFEFTVMVVGESGLGKSTLLNSLFLTDL-YTPSSYPSIKEKLNKTVEVKPCTVELKEGGVRLRLTVVDTPGFGDAVDNTDCWKPVIKYIDSKFEEHLNAESRVQRS--PFPDNRVHCCLYFISPTGHSLKPLDIEFMKKLHNKVNIVPVISKADTLTTEECTRFKKQILQEIKENNISIYEFPDLGGEEDAELDAVNMRDKVPFAVVGSNTVLEV-NGKRVRARVYPWGVVEVENVEHCDFVALRNMLIRTHMQDLKDVTNDAHYENYRCDKLASM 293
BLAST of Septin-2 vs. Ensembl Nematostella
Match: EDO47409 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RLX3]) HSP 1 Score: 255.758 bits (652), Expect = 6.252e-78 Identity = 124/295 (42.03%), Postives = 193/295 (65.42%), Query Frame = 1
Query: 151 GHVGFDTLPYQLVNKAVNQGFSFNILCLGETGLGKSTLMETLFEQNF----DFTPSTHDLPE-VSLKVSNFDLKEGNVKLKLSIIESCGFGDQINKEDCVNPVISYIDGEFEKYLQEEMKIKRNLYNYHDTRVHVCLYFIAPTGHTMKSLDLVAMKKLESKVSIIPVIAKSDTITKSEMQKFKAKIMNEIQSNKINIYQFPTTDDTVRE----LNTQMNQLLPFAVVGSNDEAKMPNGKVSRVRQYPWGTVQIDNDNHCDFIRLREMLLRTNMDDLRERTHLVHYETYRKHRLIE 1008
+VGF LP Q+ K+V +GF F ++ +GE+GLGKSTL+++LF + P+ + + V ++ + +++E V+L+L+++++ GF D ++ P++ YID +FE YL++E + R N DTRVH CLYFI P GH ++ +D+ MK L +KV+I+PVIAKSD++TK+E+ + K K+++EI ++I IY FP D E +N + LPFAV+GSN ++ KV R R YPWG +++N +HCDFI+LR ML+RT+M DL++ T VHYE YR RL++
Sbjct: 16 AYVGFANLPNQVHRKSVKKGFEFTLMVVGESGLGKSTLIDSLFLTDLYDDKSIPPAKGRIGQTVHIESNTVEIEEKGVRLRLTVVDTPGFADAVDNTYSWEPIVDYIDHQFESYLRDESGLNRR--NIMDTRVHCCLYFINPHGHGLRPVDVEFMKALHTKVNIVPVIAKSDSLTKTEISRLKRKVLDEIADHEIKIYSFPECDSEDDEEFLAINKDLKASLPFAVIGSNTVIEVKGRKV-RARWYPWGYAEVENPDHCDFIKLRNMLVRTHMQDLKDVTQDVHYENYRAQRLLD 307
BLAST of Septin-2 vs. Ensembl Nematostella
Match: EDO33106 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7ST61]) HSP 1 Score: 213.386 bits (542), Expect = 1.739e-63 Identity = 111/268 (41.42%), Postives = 168/268 (62.69%), Query Frame = 1
Query: 154 HVGFDTLPYQLVNKAVNQGFSFNILCLGETGLGKSTLMETLFEQNFDFTPSTHDLPE-----VSLKVSNFDLKEGNVKLKLSIIESCGFGDQINKEDCVNPVISYIDGEFEKYLQEEMKIKRNLYNYHDTRVHVCLYFIAPTGHTMKSLDLVAMKKLESKVSIIPVIAKSDTITKSEMQKFKAKIMNEIQSNKINIYQFPTTD-DTVRELNTQMNQL---LPFAVVGSNDEAKMPNGKVSRVRQYPWGTVQIDNDNHCDFIRLREMLL 930
+VGF LP Q+ K+V +GF F ++ +GE+GLGKSTL+++LF + E V ++ S +++E VKL+L+++++ G+GD IN ++ P++ Y + +FE YL++E + R + D+RVH C YFIAPTGH +K LD+ MK L V+I+PVI K+DT+T +E+++ K ++++EI I IY+ P D D E Q QL +PFAVVGSN + GK R R YPWG V+++N HCDF +LR ML+
Sbjct: 4 YVGFANLPNQVHRKSVKKGFEFTLMVVGESGLGKSTLIDSLFLTDLYSDRKILSAEERIKKTVKIETSTVEIEERGVKLRLTVVDTPGYGDGINHKNSFKPILDYANNQFESYLKDESGLNRR--HIIDSRVHCCFYFIAPTGHGLKPLDIEFMKALHHIVNIVPVIGKADTLTPTELKEMKRRVLDEIDEYGIQIYELPQCDSDEDEEFIEQTRQLKEGMPFAVVGSNTLIDV-CGKKVRGRLYPWGVVEVENPIHCDFSKLRAMLM 268
BLAST of Septin-2 vs. Ensembl Nematostella
Match: EDO47975 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RKG1]) HSP 1 Score: 173.711 bits (439), Expect = 6.506e-50 Identity = 85/197 (43.15%), Postives = 136/197 (69.04%), Query Frame = 1
Query: 151 GHVGFDTLPYQLVNKAVNQGFSFNILCLGETGLGKSTLMETLFEQNFDFTPSTHD---LPE-VSLKVSNFDLKEGNVKLKLSIIESCGFGDQINKEDCVNPVISYIDGEFEKYLQEEMKIKRNLYNYHDTRVHVCLYFIAPTGHTMKSLDLVAMKKLESKVSIIPVIAKSDTITKSEMQKFKAKIMNEIQSNKINIY 729
G+VGFDT+ Q+ K++ +GF FN++ +G +GLGKST++ TLF+ ST +P+ V +K + ++E V+LKL+I ++ GFGDQIN + C P++ YI+ +++K+L EE+ I+R D+RVH CLYFIAPTGH +K +D+ MK+L+ V+I+PVIAK+D +T E + F+ ++ +IQ++ INI+
Sbjct: 1 GYVGFDTVQEQIRRKSLKRGFEFNLMVVGASGLGKSTMVNTLFKGKLSRPTSTGKPTIIPKTVDVKSVSHVIEEKGVRLKLTITDTPGFGDQINNDKCWEPIMDYINSQYDKFLTEEVTIERKP-RIPDSRVHCCLYFIAPTGHRLKPIDVEFMKRLDKCVNIVPVIAKADNMTLEEREAFRRRLREDIQAHNINIH 196
BLAST of Septin-2 vs. Ensembl Medaka
Match: sept6 (septin 6 [Source:NCBI gene;Acc:101158862]) HSP 1 Score: 433.335 bits (1113), Expect = 9.100e-145 Identity = 238/422 (56.40%), Postives = 323/422 (76.54%), Query Frame = 1
Query: 97 TTEVVKGLANEIRTLKINGHVGFDTLPYQLVNKAVNQGFSFNILCLGETGLGKSTLMETLFEQNFDFTPSTHDLPEVSLKVSNFDLKEGNVKLKLSIIESCGFGDQINKEDCVNPVISYIDGEFEKYLQEEMKIKRNLYNYHDTRVHVCLYFIAPTGHTMKSLDLVAMKKLESKVSIIPVIAKSDTITKSEMQKFKAKIMNEIQSNKINIYQFPTTDDTVRELNTQMNQLLPFAVVGSNDEAKMPNGKVSRVRQYPWGTVQIDNDNHCDFIRLREMLLRTNMDDLRERTHLVHYETYRKHRLIEMGFSDNE----NMSLXXXXXXXXXXXXXXXXXXXXXIRQMFFMRVKEKENQLKESDKELLAKFESLKKSNAXXXXXXXXXXXXXXXDIGNFEKRKAIVE-------QAKQGNTIKKKK 1329
+TE+ + R + ++GHVGFD++P QLVNK+VN GF FNILC+GETGLGKSTLM+TLF F+ P+ H+ P V+LK + ++L+E NV+LKL+++ + GFGDQINKED ++ +ID +FE YLQEE+KIKR L++YHDTR+H CLYFIAPTGH++KSLDLV MKKL+SKV+IIP+IAKSD I+KSE+ KFK KI +E+ SN + IYQFPT D++V E+N+ MN LPFAVVGS +E K+ N K+ + RQYPWGTVQ++N+NHCDF++LREML+R NM+DLRE+TH HYE YR+ +L EMGF D + SLQETY+ +R EL++KEEE+RQMF RVKEKE +LKE++KEL KF+ LKK + +EK+KLEE+++ L++++ F+++K E QA T+K+ K
Sbjct: 3 STEIARQAGEGARAVPLSGHVGFDSMPDQLVNKSVNHGFCFNILCVGETGLGKSTLMDTLFNTKFEGEPTQHNQPGVTLKSNTYELQESNVRLKLTMVNTVGFGDQINKEDSYKSIVEFIDAQFEAYLQEELKIKRTLHSYHDTRIHACLYFIAPTGHSLKSLDLVTMKKLDSKVNIIPIIAKSDAISKSELAKFKIKITSELVSNGVQIYQFPTDDESVAEINSTMNSHLPFAVVGSTEEVKIGN-KMVKARQYPWGTVQVENENHCDFVKLREMLIRVNMEDLREQTHTRHYELYRRCKLEEMGFKDTDPDSKPFSLQETYEAKRNEFMGELQKKEEEMRQMFVQRVKEKEAELKEAEKELHEKFDRLKKLHQDEKKKLEEKKKALDDEVNTFKQKKTAAELLLNQAQQAGGSTTLKRDK 423
BLAST of Septin-2 vs. Ensembl Medaka
Match: sept10 (septin 10 [Source:NCBI gene;Acc:101166511]) HSP 1 Score: 428.328 bits (1100), Expect = 7.942e-143 Identity = 230/403 (57.07%), Postives = 315/403 (78.16%), Query Frame = 1
Query: 97 TTEVVKGLANEIRTLKINGHVGFDTLPYQLVNKAVNQGFSFNILCLGETGLGKSTLMETLFEQNFDFTPSTHDLPEVSLKVSNFDLKEGNVKLKLSIIESCGFGDQINKEDCVNPVISYIDGEFEKYLQEEMKIKRNLYNYHDTRVHVCLYFIAPTGHTMKSLDLVAMKKLESKVSIIPVIAKSDTITKSEMQKFKAKIMNEIQSNKINIYQFPTTDDTVRELNTQMNQLLPFAVVGSNDEAKMPNGKVSRVRQYPWGTVQIDNDNHCDFIRLREMLLRTNMDDLRERTHLVHYETYRKHRLIEMGFSDNE----NMSLXXXXXXXXXXXXXXXXXXXXXIRQMFFMRVKEKENQLKESDKELLAKFESLKKSNAXXXXXXXXXXXXXXXDIGNFEKRKAIVE 1293
+++V + R L + GHVGFD+LP QLVNK++ QGF FNILC+GETG+GKSTLM+TLF NF+ S+H P+V L+ +DL+E NV+L+L+++ + GFGDQ+NK+D PV+ YID +FE YLQEE+KIKR+L+NYHD+RVH CLYFI+P+GH++KSLDLV MKKL+SKV+IIPVIAK+DTI+KSE+ KFK KIM+E+ SN + IYQFP D+TV ++NT MN LPFAVVGS +E + N K+ + RQYPWG VQ++N+ HCDF++LREML+ NM+DLRE+TH HYE YR+ +L EMGF D + +SLQ+TY+ +R+ EL+++E+E+RQ+F RVKEKE +LKE+++EL ++FE LK+ +AEEK LEE++R+ EED +F KRKA +
Sbjct: 3 SSDVARQPDKGARPLSLAGHVGFDSLPDQLVNKSICQGFCFNILCIGETGIGKSTLMDTLFNTNFENFESSHFEPQVKLRAQTYDLQETNVRLRLTVVNTVGFGDQMNKQDSYQPVVDYIDKQFESYLQEELKIKRSLHNYHDSRVHACLYFISPSGHSLKSLDLVTMKKLDSKVNIIPVIAKADTISKSELHKFKIKIMSELVSNGVQIYQFPLDDETVAKVNTTMNGHLPFAVVGSTEEVCVGN-KMVKARQYPWGVVQVENEQHCDFVKLREMLICVNMEDLREQTHSRHYELYRRCKLEEMGFKDTDPECKPVSLQQTYEAKRQEFLLELQRREDEMRQIFVQRVKEKEAELKEAERELQSRFEQLKRRHAEEKATLEEKKRLFEEDQSSFNKRKAATQ 404
BLAST of Septin-2 vs. Ensembl Medaka
Match: sept8a (septin-8-A [Source:NCBI gene;Acc:101166488]) HSP 1 Score: 422.165 bits (1084), Expect = 1.618e-140 Identity = 237/405 (58.52%), Postives = 312/405 (77.04%), Query Frame = 1
Query: 127 EIRTLKINGHVGFDTLPYQLVNKAVNQGFSFNILCLGETGLGKSTLMETLFEQNFDFTPSTHDLPEVSLKVSNFDLKEGNVKLKLSIIESCGFGDQINKEDCVNPVISYIDGEFEKYLQEEMKIKRNLYNYHDTRVHVCLYFIAPTGHTMKSLDLVAMKKLESKVSIIPVIAKSDTITKSEMQKFKAKIMNEIQSNKINIYQFPTTDDTVRELNTQMNQLLPFAVVGSNDEAKMPNGKVSRVRQYPWGTVQIDNDNHCDFIRLREMLLRTNMDDLRERTHLVHYETYRKHRLIEMGF----SDNENMSLXXXXXXXXXXXXXXXXXXXXXIRQMFFMRVKEKENQLKESDKELLAKFESLKKSNAXXXXXXXXXXXXXXXDIGNFEKRKAIVEQAKQGNTIKKKK 1329
E R L + GHVGFD+LP QLV+K+V QGF FNILC+GETG+GKSTLM TLF F+ ++H V L+ +DL+E +V LKL+I+++ GFGDQINK++ P++ YID +FE YLQEE+KIKR+L+NYHDTR+H+CLYFIAPTGH++KSLDLV MKKL+SKV+IIP+IAK+DTI+KSE+ KFK KIM+E+ SN + IYQFPT D+ V E+N+ MN LPFAVVGS +E K+ N K R RQYPWG VQ++N++HCDF++LREML+R NM+DLRE+TH HYE YR+ +L EMGF D++ +SLQETY+ +R+ +L++KEEE+RQMF +VKE E +LKE +KEL KFE LK+ + EEKRK+EE+RR LEE++ F +RK E +KK K
Sbjct: 13 EKRNLSLGGHVGFDSLPDQLVSKSVTQGFCFNILCVGETGIGKSTLMNTLFNTMFENEEASHYQNGVYLRPRTYDLQESSVHLKLTIVDTVGFGDQINKDESYKPIVDYIDTQFENYLQEELKIKRSLFNYHDTRIHICLYFIAPTGHSLKSLDLVTMKKLDSKVNIIPIIAKADTISKSELHKFKIKIMSELVSNGVQIYQFPTDDEAVSEINSSMNAHLPFAVVGSVEEVKVGN-KTVRARQYPWGVVQVENESHCDFVKLREMLIRVNMEDLREQTHARHYELYRRCKLEEMGFKDTDPDSQPISLQETYEAKRKEFLGDLQRKEEEMRQMFVNKVKETEAELKEKEKELHDKFEHLKRIHQEEKRKVEEKRRDLEEELNTFNRRKMAAETQSLSQPLKKDK 416
BLAST of Septin-2 vs. Ensembl Medaka
Match: sept8a (septin-8-A [Source:NCBI gene;Acc:101166488]) HSP 1 Score: 421.779 bits (1083), Expect = 1.156e-139 Identity = 237/405 (58.52%), Postives = 312/405 (77.04%), Query Frame = 1
Query: 127 EIRTLKINGHVGFDTLPYQLVNKAVNQGFSFNILCLGETGLGKSTLMETLFEQNFDFTPSTHDLPEVSLKVSNFDLKEGNVKLKLSIIESCGFGDQINKEDCVNPVISYIDGEFEKYLQEEMKIKRNLYNYHDTRVHVCLYFIAPTGHTMKSLDLVAMKKLESKVSIIPVIAKSDTITKSEMQKFKAKIMNEIQSNKINIYQFPTTDDTVRELNTQMNQLLPFAVVGSNDEAKMPNGKVSRVRQYPWGTVQIDNDNHCDFIRLREMLLRTNMDDLRERTHLVHYETYRKHRLIEMGF----SDNENMSLXXXXXXXXXXXXXXXXXXXXXIRQMFFMRVKEKENQLKESDKELLAKFESLKKSNAXXXXXXXXXXXXXXXDIGNFEKRKAIVEQAKQGNTIKKKK 1329
E R L + GHVGFD+LP QLV+K+V QGF FNILC+GETG+GKSTLM TLF F+ ++H V L+ +DL+E +V LKL+I+++ GFGDQINK++ P++ YID +FE YLQEE+KIKR+L+NYHDTR+H+CLYFIAPTGH++KSLDLV MKKL+SKV+IIP+IAK+DTI+KSE+ KFK KIM+E+ SN + IYQFPT D+ V E+N+ MN LPFAVVGS +E K+ N K R RQYPWG VQ++N++HCDF++LREML+R NM+DLRE+TH HYE YR+ +L EMGF D++ +SLQETY+ +R+ +L++KEEE+RQMF +VKE E +LKE +KEL KFE LK+ + EEKRK+EE+RR LEE++ F +RK E +KK K
Sbjct: 13 EKRNLSLGGHVGFDSLPDQLVSKSVTQGFCFNILCVGETGIGKSTLMNTLFNTMFENEEASHYQNGVYLRPRTYDLQESSVHLKLTIVDTVGFGDQINKDESYKPIVDYIDTQFENYLQEELKIKRSLFNYHDTRIHICLYFIAPTGHSLKSLDLVTMKKLDSKVNIIPIIAKADTISKSELHKFKIKIMSELVSNGVQIYQFPTDDEAVSEINSSMNAHLPFAVVGSVEEVKVGN-KTVRARQYPWGVVQVENESHCDFVKLREMLIRVNMEDLREQTHARHYELYRRCKLEEMGFKDTDPDSQPISLQETYEAKRKEFLGDLQRKEEEMRQMFVNKVKETEAELKEKEKELHDKFEHLKRIHQEEKRKVEEKRRDLEEELNTFNRRKMAAETQSLSQPLKKDK 416
BLAST of Septin-2 vs. Ensembl Medaka
Match: sept6 (septin 6 [Source:NCBI gene;Acc:101158862]) HSP 1 Score: 409.453 bits (1051), Expect = 5.741e-136 Identity = 229/397 (57.68%), Postives = 307/397 (77.33%), Query Frame = 1
Query: 172 LPYQLVNKAVNQGFSFNILCLGETGLGKSTLMETLFEQNFDFTPSTHDLPEVSLKVSNFDLKEGNVKLKLSIIESCGFGDQINKEDCVNPVISYIDGEFEKYLQEEMKIKRNLYNYHDTRVHVCLYFIAPTGHTMKSLDLVAMKKLESKVSIIPVIAKSDTITKSEMQKFKAKIMNEIQSNKINIYQFPTTDDTVRELNTQMNQLLPFAVVGSNDEAKMPNGKVSRVRQYPWGTVQIDNDNHCDFIRLREMLLRTNMDDLRERTHLVHYETYRKHRLIEMGFSDNE----NMSLXXXXXXXXXXXXXXXXXXXXXIRQMFFMRVKEKENQLKESDKELLAKFESLKKSNAXXXXXXXXXXXXXXXDIGNFEKRKAIVE-------QAKQGNTIKKKK 1329
+P QLVNK+VN GF FNILC+GETGLGKSTLM+TLF F+ P+ H+ P V+LK + ++L+E NV+LKL+++ + GFGDQINKED ++ +ID +FE YLQEE+KIKR L++YHDTR+H CLYFIAPTGH++KSLDLV MKKL+SKV+IIP+IAKSD I+KSE+ KFK KI +E+ SN + IYQFPT D++V E+N+ MN LPFAVVGS +E K+ N K+ + RQYPWGTVQ++N+NHCDF++LREML+R NM+DLRE+TH HYE YR+ +L EMGF D + SLQETY+ +R EL++KEEE+RQMF RVKEKE +LKE++KEL KF+ LKK + +EK+KLEE+++ L++++ F+++K E QA T+K+ K
Sbjct: 1 MPDQLVNKSVNHGFCFNILCVGETGLGKSTLMDTLFNTKFEGEPTQHNQPGVTLKSNTYELQESNVRLKLTMVNTVGFGDQINKEDSYKSIVEFIDAQFEAYLQEELKIKRTLHSYHDTRIHACLYFIAPTGHSLKSLDLVTMKKLDSKVNIIPIIAKSDAISKSELAKFKIKITSELVSNGVQIYQFPTDDESVAEINSTMNSHLPFAVVGSTEEVKIGN-KMVKARQYPWGTVQVENENHCDFVKLREMLIRVNMEDLREQTHTRHYELYRRCKLEEMGFKDTDPDSKPFSLQETYEAKRNEFMGELQKKEEEMRQMFVQRVKEKEAELKEAEKELHEKFDRLKKLHQDEKKKLEEKKKALDDEVNTFKQKKTAAELLLNQAQQAGGSTTLKRDK 396
BLAST of Septin-2 vs. Planmine SMEST
Match: SMESG000008815.1 (SMESG000008815.1) HSP 1 Score: 770.385 bits (1988), Expect = 0.000e+0 Identity = 412/412 (100.00%), Postives = 412/412 (100.00%), Query Frame = 1
Query: 94 MTTEVVKGLANEIRTLKINGHVGFDTLPYQLVNKAVNQGFSFNILCLGETGLGKSTLMETLFEQNFDFTPSTHDLPEVSLKVSNFDLKEGNVKLKLSIIESCGFGDQINKEDCVNPVISYIDGEFEKYLQEEMKIKRNLYNYHDTRVHVCLYFIAPTGHTMKSLDLVAMKKLESKVSIIPVIAKSDTITKSEMQKFKAKIMNEIQSNKINIYQFPTTDDTVRELNTQMNQLLPFAVVGSNDEAKMPNGKVSRVRQYPWGTVQIDNDNHCDFIRLREMLLRTNMDDLRERTHLVHYETYRKHRLIEMGFSDNENMSLXXXXXXXXXXXXXXXXXXXXXIRQMFFMRVKEKENQLKESDKELLAKFESLKKSNAXXXXXXXXXXXXXXXDIGNFEKRKAIVEQAKQGNTIKKKK 1329
MTTEVVKGLANEIRTLKINGHVGFDTLPYQLVNKAVNQGFSFNILCLGETGLGKSTLMETLFEQNFDFTPSTHDLPEVSLKVSNFDLKEGNVKLKLSIIESCGFGDQINKEDCVNPVISYIDGEFEKYLQEEMKIKRNLYNYHDTRVHVCLYFIAPTGHTMKSLDLVAMKKLESKVSIIPVIAKSDTITKSEMQKFKAKIMNEIQSNKINIYQFPTTDDTVRELNTQMNQLLPFAVVGSNDEAKMPNGKVSRVRQYPWGTVQIDNDNHCDFIRLREMLLRTNMDDLRERTHLVHYETYRKHRLIEMGFSDNENMSLQETYQQRRETQTKELKQKEEEIRQMFFMRVKEKENQLKESDKELLAKFESLKKSNAEEKRKLEERRRILEEDIGNFEKRKAIVEQAKQGNTIKKKK
Sbjct: 1 MTTEVVKGLANEIRTLKINGHVGFDTLPYQLVNKAVNQGFSFNILCLGETGLGKSTLMETLFEQNFDFTPSTHDLPEVSLKVSNFDLKEGNVKLKLSIIESCGFGDQINKEDCVNPVISYIDGEFEKYLQEEMKIKRNLYNYHDTRVHVCLYFIAPTGHTMKSLDLVAMKKLESKVSIIPVIAKSDTITKSEMQKFKAKIMNEIQSNKINIYQFPTTDDTVRELNTQMNQLLPFAVVGSNDEAKMPNGKVSRVRQYPWGTVQIDNDNHCDFIRLREMLLRTNMDDLRERTHLVHYETYRKHRLIEMGFSDNENMSLQETYQQRRETQTKELKQKEEEIRQMFFMRVKEKENQLKESDKELLAKFESLKKSNAEEKRKLEERRRILEEDIGNFEKRKAIVEQAKQGNTIKKKK 412
BLAST of Septin-2 vs. Planmine SMEST
Match: SMESG000076922.1 (SMESG000076922.1) HSP 1 Score: 239.195 bits (609), Expect = 1.571e-70 Identity = 122/301 (40.53%), Postives = 189/301 (62.79%), Query Frame = 1
Query: 136 TLKINGH-------VGFDTLPYQLVNKAVNQGFSFNILCLGETGLGKSTLMETLFEQNFDFTP---STHDLPEVSLKVSN--FDLKEGNVKLKLSIIESCGFGDQINKEDCVNPVISYIDGEFEKYLQEEMKIKRNLYNYHDTRVHVCLYFIAPTGHTMKSLDLVAMKKLESKVSIIPVIAKSDTITKSEMQKFKAKIMNEIQSNKINIYQFPTT----DDTVRELNTQMNQLLPFAVVGSNDEAKMPNGKVSRVRQYPWGTVQIDNDNHCDFIRLREMLLRTNMDDLRERTHLVHYETYR 990
T++ NG +GF LP Q+ KAV +GF+F ++ +GE+GLGKST + +L Q+ P S+ D+ + K+ +L E VKL+L+I+++ GFGD ++ +C P++ YID F +Y ++E I R N D RVH CLYFI+PTGH +K +D+ MK L KV+I+P+IAK+D++T+SE++ FK K+M++++ +IN YQ P +D R + ++ LPF+VVGSN +G+ R RQY WG +++N HC+F LR +LRT+M DL++ T+ + YE YR
Sbjct: 34 TIRSNGSAKNDELKLGFANLPEQMQRKAVKKGFNFTLMIVGESGLGKSTFVNSLLNQSIYTEPRDSSSEDMINSTTKIEKHFIELDEKGVKLRLTIVDTPGFGDGLDCRECWKPIVEYIDETFYQYFKDECAINRK--NIQDNRVHCCLYFISPTGHGIKPVDVELMKTLHHKVNIVPIIAKADSLTESELKIFKRKVMDDLEKYQINFYQPPICGSDEEDEFRAQDAEIRAALPFSVVGSNIIVDSDSGRKLRGRQYIWGIAEVENSKHCNFNILRTFILRTHMQDLKDVTNDLLYENYR 332
BLAST of Septin-2 vs. Planmine SMEST
Match: SMESG000048968.1 (SMESG000048968.1) HSP 1 Score: 230.72 bits (587), Expect = 9.913e-68 Identity = 114/293 (38.91%), Postives = 185/293 (63.14%), Query Frame = 1
Query: 157 VGFDTLPYQLVNKAVNQGFSFNILCLGETGLGKSTLMETLFEQNF----DFTPSTHDLPEVSLKVSNF-DLKEGNVKLKLSIIESCGFGDQINKEDCVNPVISYIDGEFEKYLQEEMKIKRNLYNYHDTRVHVCLYFIAPTGHTMKSLDLVAMKKLESKVSIIPVIAKSDTITKSEMQKFKAKIMNEIQSNKINIYQFPTTDD----TVRELNTQMNQLLPFAVVGSNDEAKMPNGKVSRVRQYPWGTVQIDNDNHCDFIRLREMLLRTNMDDLRERTHLVHYETYRKHRLIE 1008
+GF +P Q+ KAV +GF+F+I+ +GE+GLGKST + +L + + P+ + + V F +L E VKL+L+II++ GF D +N +C P+ YI+ F++Y +EE + R N D R+H CLYF+ P G +K LD+ +K+L+ K++IIPVI K+D++T E++K K KI+N+I+ ++++Y+ P + ++R L++++ LPF+++GS D G R RQY WGT +++N+ HCDF RLR LL+T+M DL++ T V YE YR + + E
Sbjct: 41 LGFGQIPDQMHRKAVKKGFNFSIMVVGESGLGKSTFVNSLLMTDLYKDREILPAFESIAVTTKIVKRFIELDEKGVKLRLTIIDTPGFNDAVNCYNCWKPIEDYINDTFDQYFKEECGLNRK--NIQDNRIHCCLYFVNPFGRGLKPLDVEVIKRLQCKINIIPVIGKADSLTADELKKLKQKILNDIERYQLDVYRLPECESDEEASIRTLDSEIKACLPFSIIGSPDIIDNTRGPKIRGRQYIWGTSEVENNKHCDFSRLRLFLLKTHMQDLKDMTSDVLYENYRANCITE 331
BLAST of Septin-2 vs. Planmine SMEST
Match: SMESG000064397.1 (SMESG000064397.1) HSP 1 Score: 224.557 bits (571), Expect = 9.288e-65 Identity = 134/367 (36.51%), Postives = 219/367 (59.67%), Query Frame = 1
Query: 157 VGFDTLPYQLVNKAVNQGFSFNILCLGETGLGKSTLMETLFEQNFDFT----PSTHDLPEVSLKVSNFDLKEGNVKLKLSIIESCGFGDQINKEDCVNPVISYIDGEFEKYLQEEMKIKRNLYNYHDTRVHVCLYFIAPTGHTMKSLDLVAMKKLESKVSIIPVIAKSDTITKSEMQKFKAKIMNEIQSNKINIYQFPTT---------DDTVRELNTQMNQLLPFAVVGSN---DEAKMPNGKVSRVRQYPWGTVQIDNDNHCDFIRLREMLLRTNMDDLRERTHLVHYETYRKHRLIEMGFSDNENMS----LXXXXXXXXXXXXXXXXXXXXXIRQMFFMRVKEKENQLKESDKELLAKFESLK 1197
+GF +L Q+ +A +GF FN++ +G +GLGKST + +L +F T PS V ++ + LKE +V LKL ++++ GFGD ++ C +P+I YID F++++ E K+ R ++ D R+H C+YFI PTGH +K LD+ MK++ KV+IIPVI KSDT+T E + FK ++N++ +KI IY FP + D V +L + + +PF+V+GSN D+ NGK R R+YPWG V+++N H DF+ L+ M++RT++ DL++ T YE YR ++ ++ N N+S + + Q +K+ EEE++Q+F + +E+ +LKES+ +L + E +K
Sbjct: 60 IGFGSLTDQVYKRAFRKGFEFNLMVVGCSGLGKSTFINSLLMSDFYNTEYLGPSKRIKKTVYIEPTTVILKENDVALKLCLVDTPGFGDAVDNSACWDPIIEYIDNRFDEHIDNENKVNRLIF--PDKRIHACIYFIQPTGHNLKPLDVEFMKRIHEKVNIIPVIGKSDTMTPEECRDFKKNVLNQLTFHKIKIYDFPESGAAYSASDNDGEVMDLK-KCREKIPFSVIGSNIFIDK----NGKKIRGRRYPWGDVEVENAEHNDFVFLKYMIMRTHLLDLKDVTSQQLYEKYRVLKMSKIAEDSNFNVSDGKDPMMQLEAEKGEQENRIKKMEEEMKQLFEQKAEERTTKLKESEIDLEKRKEHMK 419
BLAST of Septin-2 vs. Planmine SMEST
Match: SMESG000064397.1 (SMESG000064397.1) HSP 1 Score: 224.557 bits (571), Expect = 1.295e-64 Identity = 134/367 (36.51%), Postives = 219/367 (59.67%), Query Frame = 1
Query: 157 VGFDTLPYQLVNKAVNQGFSFNILCLGETGLGKSTLMETLFEQNFDFT----PSTHDLPEVSLKVSNFDLKEGNVKLKLSIIESCGFGDQINKEDCVNPVISYIDGEFEKYLQEEMKIKRNLYNYHDTRVHVCLYFIAPTGHTMKSLDLVAMKKLESKVSIIPVIAKSDTITKSEMQKFKAKIMNEIQSNKINIYQFPTT---------DDTVRELNTQMNQLLPFAVVGSN---DEAKMPNGKVSRVRQYPWGTVQIDNDNHCDFIRLREMLLRTNMDDLRERTHLVHYETYRKHRLIEMGFSDNENMS----LXXXXXXXXXXXXXXXXXXXXXIRQMFFMRVKEKENQLKESDKELLAKFESLK 1197
+GF +L Q+ +A +GF FN++ +G +GLGKST + +L +F T PS V ++ + LKE +V LKL ++++ GFGD ++ C +P+I YID F++++ E K+ R ++ D R+H C+YFI PTGH +K LD+ MK++ KV+IIPVI KSDT+T E + FK ++N++ +KI IY FP + D V +L + + +PF+V+GSN D+ NGK R R+YPWG V+++N H DF+ L+ M++RT++ DL++ T YE YR ++ ++ N N+S + + Q +K+ EEE++Q+F + +E+ +LKES+ +L + E +K
Sbjct: 75 IGFGSLTDQVYKRAFRKGFEFNLMVVGCSGLGKSTFINSLLMSDFYNTEYLGPSKRIKKTVYIEPTTVILKENDVALKLCLVDTPGFGDAVDNSACWDPIIEYIDNRFDEHIDNENKVNRLIF--PDKRIHACIYFIQPTGHNLKPLDVEFMKRIHEKVNIIPVIGKSDTMTPEECRDFKKNVLNQLTFHKIKIYDFPESGAAYSASDNDGEVMDLK-KCREKIPFSVIGSNIFIDK----NGKKIRGRRYPWGDVEVENAEHNDFVFLKYMIMRTHLLDLKDVTSQQLYEKYRVLKMSKIAEDSNFNVSDGKDPMMQLEAEKGEQENRIKKMEEEMKQLFEQKAEERTTKLKESEIDLEKRKEHMK 434 The following BLAST results are available for this feature:
BLAST of Septin-2 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99) Total hits: 5
BLAST of Septin-2 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99) Total hits: 4
BLAST of Septin-2 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99) Total hits: 5
BLAST of Septin-2 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99) Total hits: 5
BLAST of Septin-2 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99) Total hits: 5
BLAST of Septin-2 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99) Total hits: 5
BLAST of Septin-2 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt) Total hits: 5
BLAST of Septin-2 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL) Total hits: 5
BLAST of Septin-2 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99) Total hits: 5
BLAST of Septin-2 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99) Total hits: 5
BLAST of Septin-2 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46) Total hits: 5
BLAST of Septin-2 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46) Total hits: 5
BLAST of Septin-2 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99) Total hits: 5
BLAST of Septin-2 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST) Total hits: 5
Analyses
This transcript is derived from or has results from the following analyses Sequences
The following sequences are available for this feature:
transcript sequence >SMED30013132 ID=SMED30013132|Name=Septin-2|organism=Schmidtea mediterranea sexual|type=transcript|length=2406bpback to top protein sequence of SMED30013132-orf-1 >SMED30013132-orf-1 ID=SMED30013132-orf-1|Name=SMED30013132-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=413bp MTTEVVKGLANEIRTLKINGHVGFDTLPYQLVNKAVNQGFSFNILCLGETback to top Annotated Terms
The following terms have been associated with this transcript:
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
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