Aldehyde dehydrogenase family protein

Query:  121 NLSKSFFRSNQRFSCYMIQSPEYSWLKDLGLKDYNNGVYDGNNWTASGTEFEQLCPSNNKIIAKIKMSSLEDCNRCIAETYKTNKVWRNLPAPYRGEIVRQIGYRFRQKKDIIAKLLSLEVGKIYAEGKGEVQEIIDICDFATGLSRMFNGSIFPSERQNHLLLEQWNPLGVVGVISAFNFPAAVFGWNLALALVCGNSVVWKGAPSTNLTTIAVSNIIIEVLKENNLPTSIVTALCGGTDVGQALVADKRIALVSFTGSCSAGAKVQQAVTNRFGRCLLELGGNNAIIVNHDANIDMVTRSVLFAAAGTAGQRCTTTRRLLVHEDVYDLVLSKLIAAYKKLRIGDPMDENVTIGPLHTKGAVEMFKNCIDQVKSSXXXXXXXXXXXXXXXNFVQPTIVTNLAHDHPIVHNETFVPIIYVIKIKNLDQAITINNEVEQGLSSSLFTRDLSSIYRWLGPEGSDCGLVNVNIPTNGAEIGGAFGGEKMTGGGRESGSDSWKQYMRRSTCTINCGTDLPLAQGIVFE 1692
             LS  + R     S  +I  P+Y+WLK+LGL++ N GVY+G+ W   G      CP+NN+ IA+++ +S+ D    + +  +  K+W ++PAP RGEIVRQIG   R+K  ++  L+SLE+GKI  EG GEVQE +DICD+A GLSRM  G I PSER  H L+EQWNP+G+VG+I+AFNFP AV+GWN A+A++CGN  +WKGAP+T+L ++AV+ II +VL++N LP +I +  CGG D+G A+  D+R+ L+SFTGS   G +V   V  RFGR LLELGGNNAII   DA++ +V  S LFAA GTAGQRCTT RRL +HE ++D V+++L  AY ++R+G+P D NV  GPLHTK AV MF   +++ K  GG + +GG+ +   GN+V+PTIVT L HD  I H ETF PI+YV K KN ++    NNEV+QGLSSS+FT+DL  I+RWLGP+GSDCG+VNVNIPT+GAEIGGAFGGEK TGGGRESGSD+WKQYMRRSTCTIN   DLPLAQGI F+
Sbjct:   17 KLSGPWSRPAAFMSTLLINQPQYAWLKELGLREENEGVYNGS-WGGRGEVITTYCPANNEPIARVRQASVADYEETVKKAREAWKIWADIPAPKRGEIVRQIGDALREKIQVLGSLVSLEMGKILVEGVGEVQEYVDICDYAVGLSRMIGGPILPSERSGHALIEQWNPVGLVGIITAFNFPVAVYGWNNAIAMICGNVCLWKGAPTTSLISVAVTKIIAKVLEDNKLPGAICSLTCGGADIGTAMAKDERVNLLSFTGSTQVGKQVGLMVQERFGRSLLELGGNNAIIAFEDADLSLVVPSALFAAVGTAGQRCTTARRLFIHESIHDEVVNRLKKAYAQIRVGNPWDPNVLYGPLHTKQAVSMFLGAVEEAKKEGGTVVYGGKVMDRPGNYVEPTIVTGLGHDASIAHTETFAPILYVFKFKNEEEVFAWNNEVKQGLSSSIFTKDLGRIFRWLGPKGSDCGIVNVNIPTSGAEIGGAFGGEKHTGGGRESGSDAWKQYMRRSTCTINYSKDLPLAQGIKFQ 539          

Query:  121 NLSKSFFRSNQRFSCYMIQSPEYSWLKDLGLKDYNNGVYDGNNWTASGTEFEQLCPSNNKIIAKIKMSSLEDCNRCIAETYKTNKVWRNLPAPYRGEIVRQIGYRFRQKKDIIAKLLSLEVGKIYAEGKGEVQEIIDICDFATGLSRMFNGSIFPSERQNHLLLEQWNPLGVVGVISAFNFPAAVFGWNLALALVCGNSVVWKGAPSTNLTTIAVSNIIIEVLKENNLPTSIVTALCGGTDVGQALVADKRIALVSFTGSCSAGAKVQQAVTNRFGRCLLELGGNNAIIVNHDANIDMVTRSVLFAAAGTAGQRCTTTRRLLVHEDVYDLVLSKLIAAYKKLRIGDPMDENVTIGPLHTKGAVEMFKNCIDQVKSSXXXXXXXXXXXXXXXNFVQPTIVTNLAHDHPIVHNETFVPIIYVIKIKNLDQAITINNEVEQGLSSSLFTRDLSSIYRWLGPEGSDCGLVNVNIPTNGAEIGGAFGGEKMTGGGRESGSDSWKQYMRRSTCTINCGTDLPLAQGIVFE 1692
             LS  + R     S  +I  P+Y+WLK+LGL++ N GVY+G+ W   G      CP+NN+ IA+++ +S+ D    + +  +  K+W ++PAP RGEIVRQIG   R+K  ++  L+SLE+GKI  EG GEVQE +DICD+A GLSRM  G I PSER  H L+EQWNP+G+VG+I+AFNFP AV+GWN A+A++CGN  +WKGAP+T+L ++AV+ II +VL++N LP +I +  CGG D+G A+  D+R+ L+SFTGS   G +V   V  RFGR LLELGGNNAII   DA++ +V  S LFAA GTAGQRCTT RRL +HE ++D V+++L  AY ++R+G+P D NV  GPLHTK AV MF   +++ K  GG + +GG+ +   GN+V+PTIVT L HD  I H ETF PI+YV K KN ++    NNEV+QGLSSS+FT+DL  I+RWLGP+GSDCG+VNVNIPT+GAEIGGAFGGEK TGGGRESGSD+WKQYMRRSTCTIN   DLPLAQGI F+
Sbjct:   17 KLSGPWSRPAAFMSTLLINQPQYAWLKELGLREENEGVYNGS-WGGRGEVITTYCPANNEPIARVRQASVADYEETVKKAREAWKIWADIPAPKRGEIVRQIGDALREKIQVLGSLVSLEMGKILVEGVGEVQEYVDICDYAVGLSRMIGGPILPSERSGHALIEQWNPVGLVGIITAFNFPVAVYGWNNAIAMICGNVCLWKGAPTTSLISVAVTKIIAKVLEDNKLPGAICSLTCGGADIGTAMAKDERVNLLSFTGSTQVGKQVGLMVQERFGRSLLELGGNNAII---DADLSLVVPSALFAAVGTAGQRCTTARRLFIHESIHDEVVNRLKKAYAQIRVGNPWDPNVLYGPLHTKQAVSMFLGAVEEAKKEGGTVVYGGKVMDRPGNYVEPTIVTGLGHDASIAHTETFAPILYVFKFKNEEEVFAWNNEVKQGLSSSIFTKDLGRIFRWLGPKGSDCGIVNVNIPTSGAEIGGAFGGEKHTGGGRESGSDAWKQYMRRSTCTINYSKDLPLAQGIKFQ 536          

Query:  121 NLSKSFFRSNQRFSCYMIQSPEYSWLKDLGLKDYNNGVYDGNNWTASGTEFEQLCPSNNKIIAKIKMSSLEDCNRCIAETYKTNKVWRNLPAPYRGEIVRQIGYRFRQKKDIIAKLLSLEVGKIYAEGKGEVQEIIDICDFATGLSRMFNGSIFPSERQ---------------NHLLLEQWNPLGVVGVISAFNFPAAVFGWNLALALVCGNSVVWKGAPSTNLTTIAVSNIIIEVLKENNLPTSIVTALCGGTDVGQALVADKRIALVSFTGSCSAGAKVQQAVTNRFGRCLLELGGNNAIIVNHDANIDMVTRSVLFAAAGTAGQRCTTTRRLLVHEDVYDLVLSKLIAAYKKLRIGDPMDENVTIGPLHTKGAVEMFKNCIDQVKSSXXXXXXXXXXXXXXXNFVQPTIVTNLAHDHPIVHNETFVPIIYVIKIKNLDQAITINNEVEQGLSSSLFTRDLSSIYRWLGPEGSDCGLVNVNIPTNGAEIGGAFGGEKMTGGGRESGSDSWKQYMRRSTCTINCGTDLPLAQGIVFE 1692
             LS  + R     S  +I  P+Y+WLK+LGL++ N GVY+G+ W   G      CP+NN+ IA+++ +S+ D    + +  +  K+W ++PAP RGEIVRQIG   R+K  ++  L+SLE+GKI  EG GEVQE +DICD+A GLSRM  G I PSER                 H L+EQWNP+G+VG+I+AFNFP AV+GWN A+A++CGN  +WKGAP+T+L ++AV+ II +VL++N LP +I +  CGG D+G A+  D+R+ L+SFTGS   G +V   V  RFGR LLELGGNNAII   DA++ +V  S LFAA GTAGQRCTT RRL +HE ++D V+++L  AY ++R+G+P D NV  GPLHTK AV MF   +++ K  GG + +GG+ +   GN+V+PTIVT L HD  I H ETF PI+YV K KN ++    NNEV+QGLSSS+FT+DL  I+RWLGP+GSDCG+VNVNIPT+GAEIGGAFGGEK TGGGRESGSD+WKQYMRRSTCTIN   DLPLAQGI F+
Sbjct:   17 KLSGPWSRPAAFMSTLLINQPQYAWLKELGLREENEGVYNGS-WGGRGEVITTYCPANNEPIARVRQASVADYEETVKKAREAWKIWADIPAPKRGEIVRQIGDALREKIQVLGSLVSLEMGKILVEGVGEVQEYVDICDYAVGLSRMIGGPILPSERSCCVVQAGLKLLSSRSGHALIEQWNPVGLVGIITAFNFPVAVYGWNNAIAMICGNVCLWKGAPTTSLISVAVTKIIAKVLEDNKLPGAICSLTCGGADIGTAMAKDERVNLLSFTGSTQVGKQVGLMVQERFGRSLLELGGNNAIIAFEDADLSLVVPSALFAAVGTAGQRCTTARRLFIHESIHDEVVNRLKKAYAQIRVGNPWDPNVLYGPLHTKQAVSMFLGAVEEAKKEGGTVVYGGKVMDRPGNYVEPTIVTGLGHDASIAHTETFAPILYVFKFKNEEEVFAWNNEVKQGLSSSIFTKDLGRIFRWLGPKGSDCGIVNVNIPTSGAEIGGAFGGEKHTGGGRESGSDAWKQYMRRSTCTINYSKDLPLAQGIKFQ 554          

Query:  121 NLSKSFFRSNQRFSCYMIQSPEYSWLKDLGLKDYNNGVYDGNNWTASGTEFEQLCPSNNKIIAKIKMSSLEDCNRCIAETYKTNKVWRNLPAPYRGEIVRQIGYRFRQKKDIIAKLLSLEVGKIYAEGKGEVQEIIDICDFATGLSRMFNGSIFPSERQNHLLLEQWNPLGVVGVISAFNFPAAVFGWNLALALVCGNSVVWKGAPSTNLTTIAVSNIIIEVLKENNLPTSIVTALCGGTDVGQALVADKRIALVSFTGSCSAGAKVQQAVTNRFGRCLLELGGNNAIIVNHDANIDMVTRSVLFAAAGTAGQRCTTTRRLLVHEDVYDLVLSKLIAAYKKLRIGDPMDENVTIGPLHTKGAVEMFKNCIDQVKSSXXXXXXXXXXXXXXXNFVQPTIVTNLAHDHPIVHNETFVPIIYVIKIKNLDQAITINNEVEQGLSSSLFTRDLSSIYRWLGPEGSDCGLVNVNIPTNGAEIGGAFGGEKMTGGGRESGSDSWKQYMRRST 1638
             LS  + R     S  +I  P+Y+WLK+LGL++ N GVY+G+ W   G      CP+NN+ IA+++ +S+ D    + +  +  K+W ++PAP RGEIVRQIG   R+K  ++  L+SLE+GKI  EG GEVQE +DICD+A GLSRM  G I PSER  H L+EQWNP+G+VG+I+AFNFP AV+GWN A+A++CGN  +WKGAP+T+L ++AV+ II +VL++N LP +I +  CGG D+G A+  D+R+ L+SFTGS   G +V   V  RFGR LLELGGNNAII   DA++ +V  S LFAA GTAGQRCTT RRL +HE ++D V+++L  AY ++R+G+P D NV  GPLHTK AV MF   +++ K  GG + +GG+ +   GN+V+PTIVT L HD  I H ETF PI+YV K KN ++    NNEV+QGLSSS+FT+DL  I+RWLGP+GSDCG+VNVNIPT+GAEIGGAFGGEK TGGGRESGSD+WKQYMRRST
Sbjct:   17 KLSGPWSRPAAFMSTLLINQPQYAWLKELGLREENEGVYNGS-WGGRGEVITTYCPANNEPIARVRQASVADYEETVKKAREAWKIWADIPAPKRGEIVRQIGDALREKIQVLGSLVSLEMGKILVEGVGEVQEYVDICDYAVGLSRMIGGPILPSERSGHALIEQWNPVGLVGIITAFNFPVAVYGWNNAIAMICGNVCLWKGAPTTSLISVAVTKIIAKVLEDNKLPGAICSLTCGGADIGTAMAKDERVNLLSFTGSTQVGKQVGLMVQERFGRSLLELGGNNAIIAFEDADLSLVVPSALFAAVGTAGQRCTTARRLFIHESIHDEVVNRLKKAYAQIRVGNPWDPNVLYGPLHTKQAVSMFLGAVEEAKKEGGTVVYGGKVMDRPGNYVEPTIVTGLGHDASIAHTETFAPILYVFKFKNEEEVFAWNNEVKQGLSSSIFTKDLGRIFRWLGPKGSDCGIVNVNIPTSGAEIGGAFGGEKHTGGGRESGSDAWKQYMRRST 521          

Query:  121 NLSKSFFRSNQRFSCYMIQSPEYSWLKDLGLKDYNNGVYDGNNWTASGTEFEQLCPSNNKIIAKIKMSSLEDCNRCIAETYKTNKVWRNLPAPYRGEIVRQIGYRFRQKKDIIAKLLSLEVGKIYAEGKGEVQEIIDICDFATGLSRMFNGSIFPSERQNHLLLEQWNPLGVVGVISAFNFPAAVFGWNLALALVCGNSVVWKGAPSTNLTTIAVSNIIIEVLKENNLPTSIVTALCGGTDVGQALVADKRIALVSFTGSCSAGAKVQQAVTNRFGRCLLELGGNNAIIVNHDANIDMVTRSVLFAAAGTAGQRCTTTRRLLVHEDVYDLVLSKLIAAYKKLRIGDPMDENVTIGPLHTKGAVEMFKNCIDQVKSSXXXXXXXXXXXXXXXNFVQPTIVTNLAHDHPIVHNETFVPIIYVIKIKNLDQAITINNEVEQGLSSSLFTRDLSSIYRWLGPEGSDCGLVNVNIPTNGAEIGGAFGGEKMTGGGRESGSDSWKQYMRRST 1638
             LS  + R     S  +I  P+Y+WLK+LGL++ N GVY+G+ W   G      CP+NN+ IA+++ +S+ D    + +  +  K+W ++PAP RGEIVRQIG   R+K  ++  L+SLE+GKI  EG GEVQE +DICD+A GLSRM  G I PSER  H L+EQWNP+G+VG+I+AFNFP AV+GWN A+A++CGN  +WKGAP+T+L ++AV+ II +VL++N LP +I +  CGG D+G A+  D+R+ L+SFTGS   G +V   V  RFGR LLELGGNNAII   DA++ +V  S LFAA GTAGQRCTT RRL +HE ++D V+++L  AY ++R+G+P D NV  GPLHTK AV MF   +++ K  GG + +GG+ +   GN+V+PTIVT L HD  I H ETF PI+YV K KN ++    NNEV+QGLSSS+FT+DL  I+RWLGP+GSDCG+VNVNIPT+GAEIGGAFGGEK TGGGRESGSD+WKQYMRRST
Sbjct:   17 KLSGPWSRPAAFMSTLLINQPQYAWLKELGLREENEGVYNGS-WGGRGEVITTYCPANNEPIARVRQASVADYEETVKKAREAWKIWADIPAPKRGEIVRQIGDALREKIQVLGSLVSLEMGKILVEGVGEVQEYVDICDYAVGLSRMIGGPILPSERSGHALIEQWNPVGLVGIITAFNFPVAVYGWNNAIAMICGNVCLWKGAPTTSLISVAVTKIIAKVLEDNKLPGAICSLTCGGADIGTAMAKDERVNLLSFTGSTQVGKQVGLMVQERFGRSLLELGGNNAIIAFEDADLSLVVPSALFAAVGTAGQRCTTARRLFIHESIHDEVVNRLKKAYAQIRVGNPWDPNVLYGPLHTKQAVSMFLGAVEEAKKEGGTVVYGGKVMDRPGNYVEPTIVTGLGHDASIAHTETFAPILYVFKFKNEEEVFAWNNEVKQGLSSSIFTKDLGRIFRWLGPKGSDCGIVNVNIPTSGAEIGGAFGGEKHTGGGRESGSDAWKQYMRRST 521          

Query:  160 SCYMIQSPEYSWLKDLGLKDYNNGVYDGNNWTASGTEFEQLCPSNNKIIAKIKMSSLEDCNRCIAETYKTNKVWRNLPAPYRGEIVRQIGYRFRQKKDIIAKLLSLEVGKIYAEGKGEVQEIIDICDFATGLSRMFNGSIFPSERQNHLLLEQWNPLGVVGVISAFNFPAAVFGWNLALALVCGNSVVWKGAPSTNLTTIAVSNIIIEVLKENNLPTSIVTALCGGTDVGQALVADKRIALVSFTGSCSAGAKVQQAVTNRFGRCLLELGGNNAIIVNHDANIDMVTRSVLFAAAGTAGQRCTTTRRLLVHEDVYDLVLSKLIAAYKKL--RIGDPMDENVTIGPLHTKGAVEMFKNCIDQVKSSXXXXXXXXXXXXXXXNFVQPTIVTNLAHDHPIVHNETFVPIIYVIKIKNLDQAITINNEVEQGLSSSLFTRDLSSIYRWLGPEGSDCGLVNVNIPTNGAEIGGAFGGEKMTGGGRESGSDSWKQYMRRSTCTINCGTDLPLAQGIVFE 1692
            S  +I   +Y +LK+LGL + N GV+ G  W ASG   +   P+NN  IA ++  +++D    I+E  K    W  +PAP RGEIVRQIG + R +   + KL+SLE+GKI AEG GEVQE +DICD+ATGLSR   G IFPSER  H LLEQWNPLGVVGVISAFNFP AV+GWN ALALV GNSVVWK APST LT IAV+ ++ EVL  NN+  ++ + +CG  DVGQALV DKR+ LVSFTGS   G  V Q V  RFG+ LLELGGNNAIIVN DA+++MV  + +FAA GTAGQRCTTTRRL+VH+ VYD VL +L  AY +   RIG P+D N  IGPLH + AV  +K  + +  +SGGKIE+GG+ +  +GNFV PTIVT L HD P+V  ETF PI+YV+K   L++AI INNEV+QGLSSSLFT ++ ++++W+GP+GSDCG+VNVNIPT+GAEIGGAFGGEK TGGGRESGSDSW+QYMRRSTCTIN   +LPLAQGI FE
Sbjct:   20 SQLLINDSKYGFLKELGLTENNAGVFHGK-WAASGQVVQSFAPANNSPIANVQNGNVQDYEIAISEAKKAYNDWCEVPAPRRGEIVRQIGDKLRTQLQNLGKLVSLEMGKISAEGVGEVQEYVDICDYATGLSRSLEGKIFPSERPGHALLEQWNPLGVVGVISAFNFPCAVYGWNNALALVTGNSVVWKPAPSTPLTAIAVTKLVEEVLVANNVNPALCSLVCGEGDVGQALVKDKRVNLVSFTGSSEIGKIVGQQVQARFGKLLLELGGNNAIIVNEDADLNMVVPATVFAAVGTAGQRCTTTRRLIVHDKVYDQVLERLKKAYAQFESRIGCPLDSNTIIGPLHNQQAVGKYKASVAEAVASGGKIEYGGKVLERDGNFVLPTIVTGLKHDSPVVLRETFAPILYVLKFSTLEEAIAINNEVDQGLSSSLFTTNIQNVFKWMGPKGSDCGIVNVNIPTSGAEIGGAFGGEKETGGGRESGSDSWRQYMRRSTCTINYSKELPLAQGIKFE 531          

Query:  160 SCYMIQSPEYSWLKDLGLKDYNNGVYDGNNWTASGTEFEQLCPSNNKIIAKIKMSSLEDCNRCIAETYKTNKVWRNLPAPYRGEIVRQIGYRFRQKKDIIAKLLSLEVGKIYAEGKGEVQEIIDICDFATGLSRMFNGSIFPSERQNHLLLEQWNPLGVVGVISAFNFPAAVFGWNLALALVCGNSVVWKGAPSTNLTTIAVSNIIIEVLKENNLPTSIVTALCGGTDVGQALVADKRIALVSFTGSCSAGAKVQQAVTNRFGRCLLELGGNNAIIVNHDANIDMVTRSVLFAAAGTAGQRCTTTRRLLVHEDVYDLVLSKLIAAYKKL--RIGDPMDENVTIGPLHTKGAVEMFKNCIDQVKSSXXXXXXXXXXXXXXXNFVQPTIVTNLAHDHPIVHNETFVPIIYVIKIKNLDQAITINNEVEQGLSSSLFTRDLSSIYRWLGPEGSDCGLVNVNIPTNGAEIGGAFGGEKMTGGGRESGSDSWKQYMRRSTCTINCGTDLPLAQGIVFE 1692
            S  +I   +Y +LK+LGL + N GV+ G  W ASG   +   P+NN  IA ++  +++D    I+E  K    W  +PAP RGEIVRQIG + R +   + KL+SLE+GKI AEG GEVQE +DICD+ATGLSR   G IFPSER  H LLEQWNPLGVVGVISAFNFP AV+GWN ALALV GNSVVWK APST LT IAV+ ++ EVL  NN+  ++ + +CG  DVGQALV DKR+ LVSFTGS   G  V Q V  RFG+ LLELGGNNAIIVN DA+++MV  + +FAA GTAGQRCTTTRRL+VH+ VYD VL +L  AY +   RIG P+D N  IGPLH + AV  +K  + +  +SGGKIE+GG+ +  +GNFV PTIVT L HD P+V  ETF PI+YV+K   L++AI INNEV+QGLSSSLFT ++ ++++W+GP+GSDCG+VNVNIPT+GAEIGGAFGGEK TGGGRESGSDSW+QYMRRSTCTIN   +LPLAQGI FE
Sbjct:   20 SQLLINDSKYGFLKELGLTENNAGVFHGK-WAASGQVVQSFAPANNSPIANVQNGNVQDYEIAISEAKKAYNDWCEVPAPRRGEIVRQIGDKLRTQLQNLGKLVSLEMGKISAEGVGEVQEYVDICDYATGLSRSLEGKIFPSERPGHALLEQWNPLGVVGVISAFNFPCAVYGWNNALALVTGNSVVWKPAPSTPLTAIAVTKLVEEVLVANNVNPALCSLVCGEGDVGQALVKDKRVNLVSFTGSSEIGKIVGQQVQARFGKLLLELGGNNAIIVNEDADLNMVVPATVFAAVGTAGQRCTTTRRLIVHDKVYDQVLERLKKAYAQFESRIGCPLDSNTIIGPLHNQQAVGKYKASVAEAVASGGKIEYGGKVLERDGNFVLPTIVTGLKHDSPVVLRETFAPILYVLKFSTLEEAIAINNEVDQGLSSSLFTTNIQNVFKWMGPKGSDCGIVNVNIPTSGAEIGGAFGGEKETGGGRESGSDSWRQYMRRSTCTINYSKELPLAQGIKFE 531          

Query:  259 SGTEFEQLCPSNNKIIAKIKMSSLEDCNRCIAETYKTNKVWRNLPAPYRGEIVRQIGYRFRQKKDIIAKLLSLEVGKIYAEGKGEVQEIIDICDFATGLSRMFNGSIFPSERQNHLLLEQWNPLGVVGVISAFNFPAAVFGWNLALALVCGNSVVWKGAPSTNLTTIAVSNIIIEVLKENNLPTSIVTALCGGTDVGQALVADKRIALVSFTGSCSAGAKVQQAVTNR-FGRCLLELGGNNAIIVNHDANIDMVTRSVLFAAAGTAGQRCTTTRRLLVHEDVYDLVLSKLIAAYKKLRIGDPMDENVTIG---PLHTKGAVEMF-KNCIDQVKSSXXXXXXXXXXXXXXXNFVQPTIVTNLAHDHPIVHNETFVPIIYVIKIKNLDQAITINNEVEQGLSSSLFTRDLSSIYRWLGPEGSDCGLVNVNIPTNGAEIGGAFGGEKMTGGGRESGSDSWKQYMRRSTCTINCGT 1659
            S  +FE + P + K +A    ++ +  +  + E  K  K W       R EI+++ G   +   + IA    +  GK  AE K +V   +D   F +G++    G   P +   +    +  P+GVV  I A+N+P     W  A AL CGN+V++K +P + +T +    I+ E+LK   LP  +   + G  +  Q L+    ++ VSFTGS   G K+ +A  +R      LELGG +A+IV  DA+ID      + A   + GQ C+   ++LVH+ V      KL+   +K++IGDP+ E+  +G       +  VE +    I +  +     +         G ++ P I+T +     +   E F  ++ +I     D+AI I N+ + GL++ L T+DLS  YR    E  + G V VN   + + +   FGG   +G GRE+G+   + Y    +  +N GT
Sbjct:   35 SDRKFEVIEPRSGKPMATWHYATRDQVDLTVKEAKKAQKQWAKSSWMERSEILKKTGDLLKTHCNDIAYWECISNGKPIAEAKADVLSCVDTFYFYSGIASDLLGQHVPLDASRYAYTRRL-PVGVVAAIGAWNYPIQTCSWKTAPALACGNAVIYKPSPLSPVTAL----ILAEILKSAGLPDGVFNVIQGDAETAQDLIHHDGVSKVSFTGSIPTGKKIMKACADRNIKPVTLELGGKSALIVFDDADIDSAVSCAMMANFYSQGQVCSNASKVLVHKSVLKEFTKKLVDHTQKMKIGDPLKEDTQVGSHISAEHRNKVEGYISTAIAEGATKLCGGDRVAVHGLENGFYLSPCILTGITPKMTVYREEIFGSVLLIIPFDTEDEAIKIANDTDMGLAAGLVTKDLSRSYRV--SEQLNAGNVYVNTYNDVSPL-VPFGGVGESGFGRENGTAVLEHYTHLKSVFVNTGT 498          

Query:  259 SGTEFEQLCPSNNKIIAKIKMSSLEDCNRCIAETYKTNKVWRNLPAPYRGEIVRQIGYRFRQKKDIIAKLLSLEVGKIYAEGKGEVQEIIDICDFATGLSRMFNGSIFPSERQNHLLLEQWNPLGVVGVISAFNFPAAVFGWNLALALVCGNSVVWKGAPSTNLTTIAVSNIIIEVLKENNLPTSIVTALCGGTDVGQALVADKRIALVSFTGSCSAGAKVQQAVTNR-FGRCLLELGGNNAIIVNHDANIDMVTRSVLFAAAGTAGQRCTTTRRLLVHEDVYDLVLSKLIAAYKKLRIGDPMDENVTIG---PLHTKGAVEMF-KNCIDQVKSSXXXXXXXXXXXXXXXNFVQPTIVTNLAHDHPIVHNETFVPIIYVIKIKNLDQAITINNEVEQGLSSSLFTRDLSSIYRWLGPEGSDCGLVNVNIPTNGAEIGGAFGGEKMTGGGRESGSDSWKQYMRRSTCTINCGT 1659
            S  +FE + P + K +A    ++ +  +  + E  K  K W       R EI+++ G   +   + IA    +  GK  AE K +V   +D   F +G++    G   P +   +    +  P+GVV  I A+N+P     W  A AL CGN+V++K +P + +T +    I+ E+LK   LP  +   + G  +  Q L+    ++ VSFTGS   G K+ +A  +R      LELGG +A+IV  DA+ID      + A   + GQ C+   ++LVH+ V      KL+   +K++IGDP+ E+  +G       +  VE +    I +  +     +         G ++ P I+T +     +   E F  ++ +I     D+AI I N+ + GL++ L T+DLS  YR    E  + G V VN   + + +   FGG   +G GRE+G+   + Y    +  +N GT
Sbjct:   35 SDRKFEVIEPRSGKPMATWHYATRDQVDLTVKEAKKAQKQWAKSSWMERSEILKKTGDLLKTHCNDIAYWECISNGKPIAEAKADVLSCVDTFYFYSGIASDLLGQHVPLDASRYAYTRRL-PVGVVAAIGAWNYPIQTCSWKTAPALACGNAVIYKPSPLSPVTAL----ILAEILKSAGLPDGVFNVIQGDAETAQDLIHHDGVSKVSFTGSIPTGKKIMKACADRNIKPVTLELGGKSALIVFDDADIDSAVSCAMMANFYSQGQVCSNASKVLVHKSVLKEFTKKLVDHTQKMKIGDPLKEDTQVGSHISAEHRNKVEGYISTAIAEGATKLCGGDRVAVHGLENGFYLSPCILTGITPKMTVYREEIFGSVLLIIPFDTEDEAIKIANDTDMGLAAGLVTKDLSRSYRV--SEQLNAGNVYVNTYNDVSPL-VPFGGVGESGFGRENGTAVLEHYTHLKSVFVNTGT 498          

Query:  259 SGTEFEQLCPSNNKIIAKIKMSSLEDCNRCIAETYKTNKVWRNLPAPYRGEIVRQIGYRFRQKKDIIAKLLSLEVGKIYAEGKGEVQEIIDICDFATGLSRMFNGSIFPSERQNHLLLEQWNPLGVVGVISAFNFPAAVFGWNLALALVCGNSVVWKGAPSTNLTTIAVSNIIIEVLKENNLPTSIVTALCGGTDVGQALVADKRIALVSFTGSCSAGAKVQQAVTNR-FGRCLLELGGNNAIIVNHDANIDMVTRSVLFAAAGTAGQRCTTTRRLLVHEDVYDLVLSKLIAAYKKLRIGDPMDENVTIG---PLHTKGAVEMF-KNCIDQVKSSXXXXXXXXXXXXXXXNFVQPTIVTNLAHDHPIVHNETFVPIIYVIKIKNLDQAITINNEVEQGLSSSLFTRDLSSIYRWLGPEGSDCGLVNVNIPTNGAEIGGAFGGEKMTGGGRESGSDSWKQYMRRSTCTINCGT 1659
            S  +FE + P + K +A    ++ +  +  + E  K  K W       R EI+++ G   +   + IA    +  GK  AE K +V   +D   F +G++    G   P +   +    +  P+GVV  I A+N+P     W  A AL CGN+V++K +P + +T +    I+ E+LK   LP  +   + G  +  Q L+    ++ VSFTGS   G K+ +A  +R      LELGG +A+IV  DA+ID      + A   + GQ C+   ++LVH+ V      KL+   +K++IGDP+ E+  +G       +  VE +    I +  +     +         G ++ P I+T +     +   E F  ++ +I     D+AI I N+ + GL++ L T+DLS  YR    E  + G V VN   + + +   FGG   +G GRE+G+   + Y    +  +N GT
Sbjct:  219 SDRKFEVIEPRSGKPMATWHYATRDQVDLTVKEAKKAQKQWAKSSWMERSEILKKTGDLLKTHCNDIAYWECISNGKPIAEAKADVLSCVDTFYFYSGIASDLLGQHVPLDASRYAYTRRL-PVGVVAAIGAWNYPIQTCSWKTAPALACGNAVIYKPSPLSPVTAL----ILAEILKSAGLPDGVFNVIQGDAETAQDLIHHDGVSKVSFTGSIPTGKKIMKACADRNIKPVTLELGGKSALIVFDDADIDSAVSCAMMANFYSQGQVCSNASKVLVHKSVLKEFTKKLVDHTQKMKIGDPLKEDTQVGSHISAEHRNKVEGYISTAIAEGATKLCGGDRVAVHGLENGFYLSPCILTGITPKMTVYREEIFGSVLLIIPFDTEDEAIKIANDTDMGLAAGLVTKDLSRSYRV--SEQLNAGNVYVNTYNDVSPL-VPFGGVGESGFGRENGTAVLEHYTHLKSVFVNTGT 682          

Query:  169 MIQSPEYSWLKDLGLKDYNNGVYDGNNWTASGTEFEQLCPSNNKIIAKIKMSSLEDCNRCIAETYKTNKVWRNLPAPYRGEIVRQIGYRFRQKKDIIAKLLSLEVGKIYAEGKGEVQEIIDICDFATGLSRMFNGSIFPSERQNHLLLEQWNPLGVVGVISAFNFPAAVFGWNLALALVCGNSVVWKGAPSTNLTTIAVSNIIIEVLKENNLPTSIVTALCGGTDVGQALVADKRIALVSFTGSCSAGAKVQQAVTNRFGRCLLELGGNNAIIVNHDANIDMVTRSVLFAAAGTAGQRCTTTRRLLVHEDVYDLVLSKLIAAYKKL--RIGDPMDENVTIGPLHTKGAVEMFKNCIDQVKSSXXXXXXXXXXXXXXXNFVQPTIVTNLAHDHPIVHNETFVPIIYVIKIKNLDQAITINNEVEQGLSSSLFTRDLSSIYRWLGPEGSDCGLVNVNIPTNGAEIGGAFGGEKMTGGGRESGSDSWKQYMRRSTCTINCGTDLPLAQGIVF 1689
            +I  PEYS+LK+LGL+  N GVY G  W   G       P   + IAK++  ++++    I    +  K WR +PAP RGEIVRQIG   R+ K+ + KL+SLEVGKIY+EG+GEVQE IDICD+A GLSR+++G +  SER +H +LE W PLGVVGVISA+NFP AVFGWN A+AL  GNSV+WKGAPST L ++A + I+ EVL+ NNLP  +VT   GGTDVGQ LVADKR+ LVSFTGSC  G  V   V  RFG+ +LELGGNNA+I++  AN+ M   + LF   GT+GQRCTTTRR++VHE ++D  + +L+  YK+L  +IG  ++    +GP+HT+  VE +K  I + KS GG + FGG  I  +G +V+PT++T L HD  +VH ETF PI+Y++K KN+DQAI  NNEVEQGLSS++FT ++   ++W+G +GSDCG+VN+N  TNGAEIGGAFGGEK TGGGRESGSD+WKQY +R+T T+N   +L  AQG+VF
Sbjct:   31 LIDQPEYSFLKELGLERDNPGVYSGQ-WQGRGPSVTSYDPGTGQPIAKVRQGNVQELEHTIGLAVEAYKQWRQVPAPVRGEIVRQIGDELRKYKEPLGKLVSLEVGKIYSEGQGEVQEFIDICDYAVGLSRIYSGQLINSERADHSILEAWRPLGVVGVISAYNFPNAVFGWNAAIALTTGNSVLWKGAPSTPLVSVATTKIVAEVLRRNNLP-PVVTLCQGGTDVGQTLVADKRVNLVSFTGSCQTGRDVGVEVQRRFGKVILELGGNNALIIDESANVKMALDAALFGCIGTSGQRCTTTRRIIVHEKLHDQFVKELVGKYKQLISKIGHQLEAQTLVGPVHTQQNVENYKAAIAEAKSLGGTVAFGGNVIQRDGFYVEPTVITGLPHDASVVHRETFAPIVYILKAKNVDQAIEWNNEVEQGLSSAIFTENIGQAFKWIGAKGSDCGIVNINTTTNGAEIGGAFGGEKATGGGRESGSDAWKQYCKRATITVNHSGELACAQGVVF 537          

Query:  229 GVYDGNNW--TASGTEFEQLCPSNNKIIAKIKMSSLEDCNRCIA---ETYKTNKVWRNLPAPYRGEIVRQIGYRFRQKKDIIAKLLSLEVGKIYAEGKG-EVQEIIDICDFATGLSRMFNGSIFPSERQNHLLLEQWNPLGVVGVISAFNFPAAVFGWNLALALVCGNSVVWKGAPSTNLTTIAVSNIIIEVLKENNLPTSIVTALCGGTDVGQALVADKRIALVSFTGSCSAGAKVQQAVTN-RFGRCLLELGGNNAIIVNHDANIDMVTRSVLFAAAGTAGQRCTTTRRLLVHEDVYDLVLSKLIAAYKKLRIGDPMDENVTIGPLHTKGAVEMFKNCIDQVKSSXXXXXXXXXXXXXXXN-FVQPTIVTNLAHDHPIVHNETFVPIIYVIKIKNLDQAITINNEVEQGLSSSLFTRDLSSIYRWLGPEGSDCGLVNVNIPTNGAEIGGAFGGEKMTGGGRESGSDSWKQY 1623
            GV+  N W  + SG  FE + P+  ++IA+I+ +  ED +  +      +K    WR + A  RG ++ ++     + +  +A L +L+ GK Y+     ++   I    +  G +   +G   P +  +     +  P+GV G I  +NFP  +  W L  AL  GN++V K A  T+LT + ++ ++    KE   P  +V  + G    G AL     +  V+FTGS   G  +Q A  N    R  LELGG +  I+  D ++D    +  F      GQ C    R  V + +YD  + +     KK  +G+P D N   GP   +  +E     I   K  G K+  GG         FVQPT+  ++  D  I   E F P+  +I+ K LD+ I   N  E GL++++FT+DL      +G  G   G V VN   N       FGG KM+G GRE+G  +   Y
Sbjct:   41 GVFINNEWHKSKSGKIFETINPTTAEVIAEIQCADKEDIDIAVQAARNAFKLGSPWRRMDASERGRLLYRLADLMERDQVYLASLETLDNGKPYSMSYNVDLPTAIKNLRYFAGWADKNHGKTIPMD-GDFFTYTRHEPVGVCGQIIPWNFPILMMAWKLGPALATGNTIVLKPAEQTSLTALYIAQLV----KEAGFPEGVVNVVPGFGTAGAALANHCDVDKVAFTGSTDVGKLIQLASGNTNLKRVTLELGGKSPNIILSDTDMDYAVETAHFGLFFNMGQCCCAGSRTFVEDKIYDEFVERSAERAKKRTVGNPFDLNTEQGPQVNEEQMEKILGMIKTGKKQGAKLVAGGSRPEGLPGYFVQPTVFADVQDDMTIAREEIFGPVQQLIRFKKLDEVIERANNSEYGLAAAVFTKDLDKANYIVG--GLRAGTVWVNT-YNVLAAQAPFGGYKMSGHGRENGEYALSNY 505          

Query:  229 GVYDGNNW--TASGTEFEQLCPSNNKIIAKIKMSSLEDCNRCIA---ETYKTNKVWRNLPAPYRGEIVRQIGYRFRQKKDIIAKLLSLEVGKIYAEGKG-EVQEIIDICDFATGLSRMFNGSIFPSERQNHLLLEQWNPLGVVGVISAFNFPAAVFGWNLALALVCGNSVVWKGAPSTNLTTIAVSNIIIEVLKENNLPTSIVTALCGGTDVGQALVADKRIALVSFTGSCSAGAKVQQAVTN-RFGRCLLELGGNNAIIVNHDANIDMVTRSVLFAAAGTAGQRCTTTRRLLVHEDVYDLVLSKLIAAYKKLRIGDPMDENVTIGPLHTKGAVEMFKNCIDQVKSSXXXXXXXXXXXXXXXN-FVQPTIVTNLAHDHPIVHNETFVPIIYVIKIKNLDQAITINNEVEQGLSSSLFTRDLSSIYRWLGPEGSDCGLVNVNIPTNGAEIGGAFGGEKMTGGGRESGSDSWKQY 1623
            GV+  N W  + SG  FE + P+  ++IA+I+ +  ED +  +      +K    WR + A  RG ++ ++     + +  +A L +L+ GK Y+     ++   I    +  G +   +G   P +  +     +  P+GV G I  +NFP  +  W L  AL  GN++V K A  T+LT + ++ ++    KE   P  +V  + G    G AL     +  V+FTGS   G  +Q A  N    R  LELGG +  I+  D ++D    +  F      GQ C    R  V + +YD  + +     KK  +G+P D N   GP   +  +E     I   K  G K+  GG         FVQPT+  ++  D  I   E F P+  +I+ K LD+ I   N  E GL++++FT+DL      +G  G   G V VN   N       FGG KM+G GRE+G  +   Y
Sbjct:   41 GVFINNEWHKSKSGKIFETINPTTAEVIAEIQCADKEDIDIAVQAARNAFKLGSPWRRMDASERGRLLYRLADLMERDQVYLASLETLDNGKPYSMSYNVDLPTAIKNLRYFAGWADKNHGKTIPMD-GDFFTYTRHEPVGVCGQIIPWNFPILMMAWKLGPALATGNTIVLKPAEQTSLTALYIAQLV----KEAGFPEGVVNVVPGFGTAGAALANHCDVDKVAFTGSTDVGKLIQLASGNTNLKRVTLELGGKSPNIILSDTDMDYAVETAHFGLFFNMGQCCCAGSRTFVEDKIYDEFVERSAERAKKRTVGNPFDLNTEQGPQVNEEQMEKILGMIKTGKKQGAKLVAGGSRPEGLPGYFVQPTVFADVQDDMTIAREEIFGPVQQLIRFKKLDEVIERANNSEYGLAAAVFTKDLDKANYIVG--GLRAGTVWVNT-YNVLAAQAPFGGYKMSGHGRENGEYALSNY 505          

Query:  253 TASGTEFEQLCPSNNKIIAKIKMSSLEDCN---RCIAETYKTNKVWRNLPAPYRGEIVRQIGYRFRQKKDIIAKLLSLEVGKIYAEGKGEVQEIIDICDFATGLSRMFNGSIFPSERQNHLLLEQWNPLGVVGVISAFNFPAAVFGWNLALALVCGNSVVWKGAPSTNLTTIAVSNIIIEVLKENNLPTSIVTALCG-GTDVGQALVADKRIALVSFTGSCSAGAKVQQAV-TNRFGRCLLELGGNNAIIVNHDANIDMVTRSVLFAAAGTAGQRCTTTRRLLVHEDVYDLVLSKLIAAYKKLRIGDPMDENVTIGPLHTKGAVEMFKNCIDQVKSSXXXXXXXXXXXXXXXNFVQPTIVTNLAHDHPIVHNETFVPIIYVIKIKNLDQAITINNEVEQGLSSSLFTRDLSSIYRWLGPEGSDCGLVNVN-----IPTNGAEIGGAFGGEKMTGGGRESGSDSWKQYMRRSTCTI 1647
            + SG  F    P+ +K I ++      D +   +   + +  +  WR L    R  ++ ++     + K  +A L + + GK YAE   +V   I    +  G +  F G   P+     + + +  P+GVVG I  +N+P  +  W    AL  G +++ K A  T LT + ++ +     KE   P  ++  + G G   G A+ A   IA V+FTGS   G  V QA  T+   R  LELGG + ++V  DA+ID    +   A     GQ C    R  VHE +YD  ++K  A  K  ++G+P ++NV  GP      +      I+  K  G K++ GG+ IG  G FV+PT+ +++  D  I   E F P+  + K  +L++ I   N V+ GL++ + T D++   ++      D G V +N     +P+        FGG K +G GRE G D    Y+   T T+
Sbjct:   22 SVSGKTFATFNPATSKEIVQVSEGDKADIDLAVKAAKKAFHRDSEWRKLSPLQRTNLMNKLCALMDRDKAFLASLETQDNGKPYAEALFDVTYSILTLQYYAGWTDKFFGDTIPA--GGFVSMTRKEPVGVVGQIIPWNYPLLMLAWKWGPALAVGCTIIMKPAEQTPLTALHMAALA----KEAGFPAGVINVVNGFGPTAGAAISAHPDIAKVAFTGSVEIGRIVMQAAATSNLKRVSLELGGKSPVVVFDDADIDFAVETTHEALFSNHGQSCCAGSRTYVHEKIYDEFVAKAAAKAKARKVGNPFEQNVQQGPQIDDDMLTKVLGYIESGKKEGAKLQAGGKRIGNVGFFVEPTVFSDVKDDMRIAQEEIFGPVQSIFKFSSLEEMIDRANNVQYGLAAGVITNDINKALKFA--NNVDAGSVWINCYDAVLPST------PFGGYKHSGIGRELGKDGLDNYLETKTITM 482          

Query:  253 TASGTEFEQLCPSNNKIIAKIKMSSLEDCN---RCIAETYKTNKVWRNLPAPYRGEIVRQIGYRFRQKKDIIAKLLSLEVGKIYAEGKGEVQEIIDICDFATGLSRMFNGSIFPSERQNHLLLEQWNPLGVVGVISAFNFPAAVFGWNLALALVCGNSVVWKGAPSTNLTTIAVSNIIIEVLKENNLPTSIVTALCG-GTDVGQALVADKRIALVSFTGSCSAGAKVQQAV-TNRFGRCLLELGGNNAIIVNHDANIDMVTRSVLFAAAGTAGQRCTTTRRLLVHEDVYDLVLSKLIAAYKKLRIGDPMDENVTIGPLHTKGAVEMFKNCIDQVKSSXXXXXXXXXXXXXXXNFVQPTIVTNLAHDHPIVHNETFVPIIYVIKIKNLDQAITINNEVEQGLSSSLFTRDLSSIYRWLGPEGSDCGLVNVNIPTNGAEIGGAFGGEKMTGGGRESGSDSWKQYMRRSTCTI 1647
            + SG  F    P+ +K I ++      D +   +   + +  +  WR L    R  ++ ++     + K  +A L + + GK YAE   +V   I    +  G +  F G   P+     + + +  P+GVVG I  +N+P  +  W    AL  G +++ K A  T LT + ++ +     KE   P  ++  + G G   G A+ A   IA V+FTGS   G  V QA  T+   R  LELGG + ++V  DA+ID    +   A     GQ C    R  VHE +YD  ++K  A  K  ++G+P ++NV  GP      +      I+  K  G K++ GG+ IG  G FV+PT+ +++  D  I   E F P+  + K  +L++ I   N V+ GL++ + T D++   ++      D G V +N   +       FGG K +G GRE G D    Y+   T T+
Sbjct:   45 SVSGKTFATFNPATSKEIVQVSEGDKADIDLAVKAAKKAFHRDSEWRKLSPLQRTNLMNKLCALMDRDKAFLASLETQDNGKPYAEALFDVTYSILTLQYYAGWTDKFFGDTIPA--GGFVSMTRKEPVGVVGQIIPWNYPLLMLAWKWGPALAVGCTIIMKPAEQTPLTALHMAALA----KEAGFPAGVINVVNGFGPTAGAAISAHPDIAKVAFTGSVEIGRIVMQAAATSNLKRVSLELGGKSPVVVFDDADIDFAVETTHEALFSNHGQSCCAGSRTYVHEKIYDEFVAKAAAKAKARKVGNPFEQNVQQGPQIDDDMLTKVLGYIESGKKEGAKLQAGGKRIGNVGFFVEPTVFSDVKDDMRIAQEEIFGPVQSIFKFSSLEEMIDRANNVQYGLAAGVITNDINKALKF--ANNVDAGSVWINC-YDAVLPSTPFGGYKHSGIGRELGKDGLDNYLETKTITM 505          

Query:  157 FSCYMIQSPEYSWLKDLGLKDYNNGVYDGNNWTASGTEFEQLCPSNNKIIAKIKMSSLEDCNRCIAETYKTNKVWRNLPAPYRGEIVRQIGYRFRQKKDIIAKLLSLEVGKIYAEGKGEVQEIIDICDFATGLSRMFNGSIFPSERQNHLLLEQWNPLGVVGVISAFNFPAAVFGWNLALALVCGNSVVWKGAPSTNLTTIAVSNIIIEVLKENNLPTSIVTALCGGTDVGQALVADKRIALVSFTGSCSAGAKVQQAVTNRFGRCLLELGGNNAIIVNHDANIDMVTRSVLFAAAGTAGQRCTTTRRLLVHEDVYDLVLSKLIAAYKKLRIGDPMDENVTIGPLHTKGAVEMFKNCIDQVKSSXXXXXXXXXXXXXXXNFVQPTIVTNLAHDHPIVHNETFVPIIYVIKIKNLDQAITINNEVEQGLSSSLFTRDLSSIYRWLGPEGSDCGLVNVNIPTNGAEIGGAFGGEKMTGGGRESGSDSWKQYMRRSTCTINCGTDLPLAQGIVFE 1692
             S  +I  PEY+WLK+LGLK+ N+GVY+G+ W   G      CP+NN+ IA+++ +++ +    I +     KVW ++PAP RGEIVRQIG   R+K   +  L+SLE+GKIY EG GEVQE +D+CD+A GLSRM  G I PSER  H+L+EQWNP+G+VG+I+AFNFP AV+GWN A+AL+CGN+ +WKGAP+T LT++AV+ I+ EVL++N+LP +I +  CGG D+G A+  D+R+ L+SFTGS   G +V   V  RFGR LLELGGNNAIIV  DA++ +V  S +FA+ GTAGQRCTTTRRL++HE ++D V+ ++  AYK++RIGDP D N   GPLHTK AV+ +   I+Q K  GG +  GG+ +   GN+V+PTI+T L H+  IVH ETFVPI+YV+K K  ++A + NNEV+QGLSSS+FT+D+  ++RWLGP+GSDCG+VNVNIPT+GAEIGGAFGGEK TGGGRESGSDSWKQYMRRSTCTIN   DLPLAQGI FE
Sbjct:   31 MSTLLINQPEYNWLKELGLKEDNDGVYNGS-WGGQGEVVTSYCPANNEPIARVRQATIAEYEETIQKALDAWKVWADVPAPKRGEIVRQIGEALRRKIKALGSLVSLEMGKIYVEGVGEVQEYVDVCDYAVGLSRMIGGPILPSERPGHVLIEQWNPVGLVGIITAFNFPVAVYGWNNAIALICGNACLWKGAPTTPLTSVAVTKIVAEVLEQNHLPGAICSMTCGGADIGMAMAKDERVGLLSFTGSTHVGKQVAMMVQERFGRQLLELGGNNAIIVFEDADLSLVVPSAVFASVGTAGQRCTTTRRLMLHESIHDEVVERIAKAYKQIRIGDPWDPNTLYGPLHTKQAVQQYLAAIEQAKQQGGTLVCGGKIMDRPGNYVEPTIITGLPHNASIVHTETFVPILYVLKFKTEEEAFSWNNEVKQGLSSSIFTKDMGRVFRWLGPKGSDCGIVNVNIPTSGAEIGGAFGGEKHTGGGRESGSDSWKQYMRRSTCTINYSKDLPLAQGIKFE 541          

Query:  232 VYDGNNW--TASGTEFEQLCPSNNKIIAKIKMSSLEDCNRCIA---ETYKTNKVWRNLPAPYRGEIVRQIGYRFRQKKDIIAKLLSLEVGKIYAEGKG-EVQEIIDICDFATGLSRMFNGSIFPSERQNHLLLEQWNPLGVVGVISAFNFPAAVFGWNLALALVCGNSVVWKGAPSTNLTTIAVSNIIIEVLKENNLPTSIVTALCG-GTDVGQALVADKRIALVSFTGSCSAGAKVQQAV-TNRFGRCLLELGGNNAIIVNHDANIDMVTRSVLFAAAGTAGQRCTTTRRLLVHEDVYDLVLSKLIAAYKKLRIGDPMDENVTIGPLHTKGAVEMFKNCIDQVKSSXXXXXXXXXXXXXXXNFVQPTIVTNLAHDHPIVHNETFVPIIYVIKIKNLDQAITINNEVEQGLSSSLFTRDLSSIYRWLGPEGSDCGLVNVNIPTNGAEIGGAFGGEKMTGGGRESGSDSWKQYMRRSTCTIN 1650
            ++  N W  + SG  F    P+  + I  ++ S   D ++ +      +    VWR + A  RG+++ ++     +    +A L SL+ GK +      ++Q II    +  G +   +GS  P + +    L +  P+GV G I  +NFP  +  W L  AL CGN+VV K A  T LT + +  +I    KE   P  +V  L G G   G A+ +   I  V+FTGS   G  +Q+A   +   R  LELGG +  I+  DA+ ++             GQ CT   R+ V E +YD  + + +   ++ ++G+P D     GP  ++         I    + G K+E GG+   T+G FV+PT+ +N+     I   E F P+  ++K K +++ I   N  E GL++++FTRD+S             G V +N   N       FGG KM+G GRE G    K+Y    T T+ 
Sbjct:   40 IFINNEWHDSVSGKVFHTYNPATGEKICDVQESDKADVDKAVQAARSAFSLGSVWRKMDASERGKLLFKLADLVERDSAYLATLESLDSGKPFLPCFFVDLQGIIKTFRYYAGWADKIHGSTIPIDGE-FFTLTRHEPIGVCGQIIPWNFPLVMTAWKLGPALSCGNTVVLKPAEQTPLTCLYLGALI----KEAGFPPGVVNILPGYGPTAGAAISSHMGIDKVAFTGSTEVGKLIQEAAGKSNLKRVTLELGGKSPNIIFADADFELALEQAHQGVFFNNGQCCTAGSRIFVEEPIYDEFVRRSVERAQRRKVGNPFDPTTEHGPQVSEEQQRRVLELIQSGITEGAKLECGGKAPPTKGFFVEPTVFSNVKDHMRIAKEEIFGPVQQIMKFKTIEEVIERANNTEYGLAAAVFTRDISKAMTISA--AVQAGTVWINC-YNALSCQCPFGGFKMSGNGRELGEIGLKEYTELKTITMK 512          

Query:  232 VYDGNNW--TASGTEFEQLCPSNNKIIAKIKMSSLEDCNRCIA---ETYKTNKVWRNLPAPYRGEIVRQIGYRFRQKKDIIAKLLSLEVGKIYAEGKG-EVQEIIDICDFATGLSRMFNGSIFPSERQNHLLLEQWNPLGVVGVISAFNFPAAVFGWNLALALVCGNSVVWKGAPSTNLTTIAVSNIIIEVLKENNLPTSIVTALCG-GTDVGQALVADKRIALVSFTGSCSAGAKVQQAV-TNRFGRCLLELGGNNAIIVNHDANIDMVTRSVLFAAAGTAGQRCTTTRRLLVHEDVYDLVLSKLIAAYKKLRIGDPMDENVTIGPLHTKGAVEMFKNCIDQVKSSXXXXXXXXXXXXXXXNFVQPTIVTNLAHDHPIVHNETFVPIIYVIKIKNLDQAITINNEVEQGLSSSLFTRDLSSIYRWLGPEGSDCGLVNVNIPTNGAEIGGAFGGEKMTGGGRESGSDSWKQYMRRSTCTIN 1650
            ++  N W  + SG  F    P+  + I  ++ S   D ++ +      +    VWR + A  RG+++ ++     +    +A L SL+ GK +      ++Q II    +  G +   +GS  P + +    L +  P+GV G I  +NFP  +  W L  AL CGN+VV K A  T LT + +  +I    KE   P  +V  L G G   G A+ +   I  V+FTGS   G  +Q+A   +   R  LELGG +  I+  DA+ ++             GQ CT   R+ V E +YD  + + +   ++ ++G+P D     GP  ++         I    + G K+E GG+   T+G FV+PT+ +N+     I   E F P+  ++K K +++ I   N  E GL++++FTRD+S             G V +N   N       FGG KM+G GRE G    K+Y    T T+ 
Sbjct:   40 IFINNEWHDSVSGKVFHTYNPATGEKICDVQESDKADVDKAVQAARSAFSLGSVWRKMDASERGKLLFKLADLVERDSAYLATLESLDSGKPFLPCFFVDLQGIIKTFRYYAGWADKIHGSTIPIDGE-FFTLTRHEPIGVCGQIIPWNFPLVMTAWKLGPALSCGNTVVLKPAEQTPLTCLYLGALI----KEAGFPPGVVNILPGYGPTAGAAISSHMGIDKVAFTGSTEVGKLIQEAAGKSNLKRVTLELGGKSPNIIFADADFELALEQAHQGVFFNNGQCCTAGSRIFVEEPIYDEFVRRSVERAQRRKVGNPFDPTTEHGPQVSEEQQRRVLELIQSGITEGAKLECGGKAPPTKGFFVEPTVFSNVKDHMRIAKEEIFGPVQQIMKFKTIEEVIERANNTEYGLAAAVFTRDISKAMTISA--AVQAGTVWINC-YNALSCQCPFGGFKMSGNGRELGEIGLKEYTELKTITMK 512          

Query:  232 VYDGNNWTAS--GTEFEQLCPSNNKIIAKIKMSSLEDCNRCIAETYKTNK---VWRNLPAPYRGEIVRQIGYRFRQKKDIIAKLLSLEVGKIYAEGKG-EVQEIIDICDFATGLSRMFNGSIFPSERQNHLLLEQWNPLGVVGVISAFNFPAAVFGWNLALALVCGNSVVWKGAPSTNLTTIAVSNIIIEVLKENNLPTSIVTALCG-GTDVGQALVADKRIALVSFTGSCSAGAKVQQAV-TNRFGRCLLELGGNNAIIVNHDANIDMVTRSVLFAAAGTAGQRCTTTRRLLVHEDVYDLVLSKLIAAYKKLRIGDPMDENVTIGPLHTKGAVEMFKNCIDQVKSSXXXXXXXXXXXXXXXNFVQPTIVTNLAHDHPIVHNETFVPIIYVIKIKNLDQAITINNEVEQGLSSSLFTRDLSSIYRWLGPEGS-DCGLVNVNIPTNGAEIGGAFGGEKMTGGGRESGSDSWKQYMRRSTCTINCGTDLPL 1671
            ++  N W  S  G +F  + P+    I  I+ +   D +  +       +   VWR + A  RG ++ ++     +++ ++A L S + GK +      ++   I    +  G +   +G   P + +N +   +  P+GV G I  +NFP  +  W +A AL CGN+VV K A  T LT + V+ +I    KE   P  +V  + G G   G A+     I  ++FTGS   G  V+ A  ++   R  LELGG N  IV  D+++ +        A    GQ CT   R+ V E VY+  +   +   K + IGDPM+   + GP   +   E     +D  K  G K+EFGG  +   G F+ PTI +++     I   E F P+  ++K +     I   N  + GL++++FTRD   + R +    + + G V VN   N       FGG KM+G GRE G  +  +Y      TI     L L
Sbjct:   34 IFINNEWHTSSKGKQFPTINPATGVKICDIEEADKADVDEAVKAAKAAGQRGSVWRRMDASSRGRLLNRLADLLERERAVLATLESKDTGKPFLHAFFVDLDGSIKTLRYYAGWTDKIHGKTMPVD-ENFVCFTKHEPIGVCGAIIPWNFPLLMLMWKIAPALACGNTVVLKPAEQTPLTALHVAALI----KEAGFPPGVVNVVPGFGPTAGAAIAGHMNIDKLAFTGSTEVGQLVKAAAASSNLKRVTLELGGKNPCIVFADSDLQLAVEETQKGAFFNQGQACTAASRVYVQEPVYEEFVRLSVERAKNIVIGDPMEPRTSHGPQIDQHQFEKILALVDSGKKEGAKLEFGGCAVEDRGLFIHPTIFSDVKDHMRIAKEEIFGPVQCIMKFECQQDVIDRANSSQFGLTAAVFTRD---VQRAMSVSAALEAGTVWVNC-YNALHAQTPFGGYKMSGNGRELGEYALAEYTEVKAITIKLSEQLRL 513          

Query:  124 LSKSFFRSNQRFSCYMIQSPEYSWLKDLGLKDYNNGVYDGNNW--TASGTEFEQLCPSNNKIIAKIKMSSLEDCNRCIA---ETYKTNKVWRNLPAPYRGEIVRQIGYRFRQKKDIIAKLLSLEVGKIYAEGKG-EVQEIIDICDFATGLSRMFNGSIFPSERQNHLLLEQWNPLGVVGVISAFNFPAAVFGWNLALALVCGNSVVWKGAPSTNLTTIAVSNIIIEVLKENNLPTSIVTALCG-GTDVGQALVADKRIALVSFTGSCSAGAKVQQAVT-NRFGRCLLELGGNNAIIVNHDANIDMVTRSVLFAAAGTAGQRCTTTRRLLVHEDVYDLVLSKLIAAYKKLRIGDPMDENVTIGPLHTKGAVEMFKNCIDQVKSSXXXXXXXXXXXXXXXNFVQPTIVTNLAHDHPIVHNETFVPIIYVIKIKNLDQAITINNEVEQGLSSSLFTRDLSSIYRWLGPEGSDCGLVNVNIPTNGAEIGGAFGGEKMTGGGRESGSDSWKQYMRRSTCTI 1647
            LS++F +  +  SC     P  +   D+    + N ++  N W    S   F  + P+  +II  +      D ++ +    + +K    WR + A  RG ++ ++     +    +A+L +L+ GK YA     +V  ++    +  G +  + G   P +  N+    +  P+GV G I  +NFP  +  W L  AL  GN+VV K A  T LT + ++++I    KE   P  +V  + G G   G A+ +   +  V+FTGS   G  +Q+A + +   +  LELGG +  I+  DAN++        A     GQ C    R  V E +YD  + + +   K   +GDP D N   GP   +   +     I   K  G K+  GG      G F+QPT+  ++  D  I   E F P++ ++K K+L++ I   N+ + GL+ ++FT+D+     ++   G   G V +N   N   +   FGG K +G GRE G    + Y    T TI
Sbjct:    6 LSRAFPQVCRISSCQHSTIPAPNVQPDV----HYNKIFINNEWHDAVSKKTFPTINPATGEIICHVAEGDKADVDKAVKAARDAFKLGSPWRRMDASQRGLLLSRLADCIERDAAYLAELETLDNGKPYAVSFSVDVPMVVKCMRYYAGWADKWEGKTIPID-GNYFCYTRHEPIGVCGQIIPWNFPLLMQAWKLGPALATGNTVVMKVAEQTPLTALYIASLI----KEVGFPAGVVNIIPGMGPTAGAAIASHMDVDKVAFTGSTDVGHLIQRASSASNLKKVTLELGGKSPNIILSDANMEEAVEQSHIALFFNQGQCCCAGTRTFVQESIYDEFVERSVERAKNRIVGDPFDLNTEQGPQVNEDQFKKVLGYISSGKREGAKLMCGGAPAAERGYFIQPTVFGDVKDDMTIAREEIFGPVMQILKFKSLEEVIERANDSKYGLAGAVFTQDIDKA-NYIS-HGLRAGTVWINC-YNVFGVQAPFGGYKASGIGREMGEYGLENYTEVKTVTI 509          

Query:  118 FNLSKSFF----RSNQRFSCYMIQSPEYSWLKDLGLKDYNNGVYDGNNWTASGTEFEQLCPSNNKIIAKIKMSSLEDCNRCIAETYKTNKVWRNLPAPYRGEIVRQIGYRFRQKKDIIAKLLSLEVGKIYAEGKGEVQEIIDICDFATGLSRMFNGSIFPSERQNHLLLEQWNPLGVVGVISAFNFPAAVFGWNLALALVCGNSVVWKGAPSTNLTTIAVSNIIIEVLKENNLPTSIVTALCGGTDVGQALVADKRIALVSFTGSCSAGAKVQQAVTNRFGRCLLELGGNNAIIVNHDANIDMVTRSVLFAAAGTAGQRCTTTRRLLVHEDVYDLVLSKLIAAYKKLRIGDPMDENVTIGPLHTKGAVEMFKNCIDQVKSSXXXXXXXXXXXXXXXNFVQPTIVTNLAHDHPIVHNETFVPIIYVIKIKNLDQAITINNEVEQGLSSSLFTRDLSSIYRWLGPEGSDCGLVNVNIPTNGAEIGGAFGGEKMTGGGRESGSDSWKQYMRRSTCTINCGTDLPLAQGIVFE 1692
            F L +  F    R +   S  +I  PEYSWLK+LGLK+ N GVY+G  W   G      CP NN  IA++K ++L++ N  + +  +  K+W ++PAP RGEIVRQIG   R+K  ++  L SLE+GKI  EG GEVQE +DICD+A GLSR+  G I PSER  H L+EQWNP+G+VG+I+AFNFP AV+GWN ALAL+CGN  +WKGAP+T+LT++AV+ I+ +V ++N LP +I +  CGG D+G A+  D+R+ LVSFTGS + G +V   V  RFGR LLELGGNNAIIV  DA++ +VT SVLFAA GTAGQRCTT RRL +HE ++D ++ KL  AY ++RIGDP   +   GPLHTK AVEM+ + ++Q K  GG +  GG+ I   GNFV+PTI+T LAHD  IVH ETF PI+YVIK K  ++A   NNEV+QGLSSS+FT+DL  I+RWLGP+GSDCGLVNVNIPT+GAEIGGAFGGEK TGGGRESGSDSWK YMRRSTCTIN   DLPLAQGI F+
Sbjct:   12 FVLKRKIFASCCRQSAAMSSLLINQPEYSWLKELGLKEDNEGVYNGT-WGGKGEVVTSYCPGNNAPIARVKQATLDEYNETVNKAKEAWKIWADIPAPKRGEIVRQIGDALRKKIKLLGHLESLEMGKILVEGVGEVQEYVDICDYAVGLSRIIGGPILPSERPGHALIEQWNPVGLVGIITAFNFPVAVYGWNNALALICGNVCLWKGAPTTSLTSVAVTKIVAQVFEDNKLPGAICSLTCGGADIGNAIAKDERVDLVSFTGSTNVGKQVALKVQERFGRKLLELGGNNAIIVFEDADLSLVTPSVLFAAVGTAGQRCTTARRLFLHESIHDEIVEKLSKAYAQVRIGDPCAPDTLCGPLHTKQAVEMYLSAVEQAKCEGGTVVCGGKVIDRPGNFVEPTIMTGLAHDAAIVHKETFAPILYVIKFKTEEEAFAWNNEVKQGLSSSIFTKDLGRIFRWLGPKGSDCGLVNVNIPTSGAEIGGAFGGEKHTGGGRESGSDSWKHYMRRSTCTINYSKDLPLAQGIKFQ 539          

Query:  118 FNLSKSFF----RSNQRFSCYMIQSPEYSWLKDLGLKDYNNGVYDGNNWTASGTEFEQLCPSNNKIIAKIKMSSLEDCNRCIAETYKTNKVWRNLPAPYRGEIVRQIGYRFRQKKDIIAKLLSLEVGKIYAEGKGEVQEIIDICDFATGLSRMFNGSIFPSERQNHLLLEQWNPLGVVGVISAFNFPAAVFGWNLALALVCGNSVVWKGAPSTNLTTIAVSNIIIEVLKENNLPTSIVTALCGGTDVGQALVADKRIALVSFTGSCSAGAKVQQAVTNRFGRCLLELGGNNAIIVNHDANIDMVTRSVLFAAAGTAGQRCTTTRRLLVHEDVYDLVLSKLIAAYKKLRIGDPMDENVTIGPLHTKGAVEMFKNCIDQVKSSXXXXXXXXXXXXXXXNFVQPTIVTNLAHDHPIVHNETFVPIIYVIKIKNLDQAITINNEVEQGLSSSLFTRDLSSIYRWLGPEGSDCGLVNVNIPTNGAEIGGAFGGEKMTGGGRESGSDSWKQYMRRST 1638
            F L +  F    R +   S  +I  PEYSWLK+LGLK+ N GVY+G  W   G      CP NN  IA++K ++L++ N  + +  +  K+W ++PAP RGEIVRQIG   R+K  ++  L SLE+GKI  EG GEVQE +DICD+A GLSR+  G I PSER  H L+EQWNP+G+VG+I+AFNFP AV+GWN ALAL+CGNSV+      T L    +  I+ +V ++N LP +I +  CGG D+G A+  D+R+ LVSFTGS + G +V   V  RFGR LLELGGNNAIIV  DA++ +VT SVLFAA GTAGQRCTT RRL +HE ++D ++ KL  AY ++RIGDP   +   GPLHTK AVEM+ + ++Q K  GG +  GG+ I   GNFV+PTI+T LAHD  IVH ETF PI+YVIK K  ++A   NNEV+QGLSSS+FT+DL  I+RWLGP+GSDCGLVNVNIPT+GAEIGGAFGGEK TGGGRESGSDSWK YMRRST
Sbjct:   12 FVLKRKIFASCCRQSAAMSSLLINQPEYSWLKELGLKEDNEGVYNGT-WGGKGEVVTSYCPGNNAPIARVKQATLDEYNETVNKAKEAWKIWADIPAPKRGEIVRQIGDALRKKIKLLGHLESLEMGKILVEGVGEVQEYVDICDYAVGLSRIIGGPILPSERPGHALIEQWNPVGLVGIITAFNFPVAVYGWNNALALICGNSVL----ECTALILSVIDRIVAQVFEDNKLPGAICSLTCGGADIGNAIAKDERVDLVSFTGSTNVGKQVALKVQERFGRKLLELGGNNAIIVFEDADLSLVTPSVLFAAVGTAGQRCTTARRLFLHESIHDEIVEKLSKAYAQVRIGDPCAPDTLCGPLHTKQAVEMYLSAVEQAKCEGGTVVCGGKVIDRPGNFVEPTIMTGLAHDAAIVHKETFAPILYVIKFKTEEEAFAWNNEVKQGLSSSIFTKDLGRIFRWLGPKGSDCGLVNVNIPTSGAEIGGAFGGEKHTGGGRESGSDSWKHYMRRST 517          

Query:  118 FNLSKSFF----RSNQRFSCYMIQSPEYSWLKDLGLKDYNNGVYDGNNWTASGTEFEQLCPSNNKIIAKIKMSSLEDCNRCIAETYKTNKVWRNLPAPYRGEIVRQIGYRFRQKKDIIAKLLSLEVGKIYAEGKGEVQEIIDICDFATGLSRMFNGSIFPSERQNHLLLEQWNPLGVVGVISAFNFPAAVFGWNLALALVCGNSVVWKGAPSTNLTTIAVSNIIIEVLKENNLPTSIVTALCGGTDVGQALVADKRIALVSFTGSCSAGAKVQQAVTNRFGRCLLELGGNNAIIVNHDANIDMVTRSVLFAAAGTAGQRCTTTRRLLVHEDVYDLVLSKLIAAYKKLRIGDPMDENVTIGPLHTKGAVEMFKNCIDQVKSSXXXXXXXXXXXXXXXNFVQPTIVTNLAHDHPIVHNETFVPIIYVIKIKNLDQAITINNEVEQGLSSSLFTRDLSSIYRWLGP---------------EGSDCGLVNVNIPTNGAEIGGAFGGEKMTGGGRESGSDSWKQYMRRST 1638
            F L +  F    R +   S  +I  PEYSWLK+LGLK+ N GVY+G  W   G      CP NN  IA++K                       +PAP RGEIVRQIG   R+K  ++  L SLE+GKI  EG GEVQE +DICD+A GLSR+  G I PSER  H L+EQWNP+G+VG+I+AFNFP AV+GWN ALAL+CGN  +WKGAP+T+LT++AV+ I+ +V ++N LP +I +  CGG D+G A+  D+R+ LVSFTGS + G +V   V  RFGR LLELGGNNAIIV  DA++ +VT SVLFAA GTAGQRCTT RRL +HE ++D ++ KL  AY ++RIGDP   +   GPLHTK AVEM+ + ++Q K  GG +  GG+ I   GNFV+PTI+T LAHD  IVH ETF PI+YVIK K  ++A   NNEV+QGLSSS+FT+DL  I+R   P                GSDCGLVNVNIPT+GAEIGGAFGGEK TGGGRESGSDSWK YMRRST
Sbjct:   12 FVLKRKIFASCCRQSAAMSSLLINQPEYSWLKELGLKEDNEGVYNGT-WGGKGEVVTSYCPGNNAPIARVK----------------------QIPAPKRGEIVRQIGDALRKKIKLLGHLESLEMGKILVEGVGEVQEYVDICDYAVGLSRIIGGPILPSERPGHALIEQWNPVGLVGIITAFNFPVAVYGWNNALALICGNVCLWKGAPTTSLTSVAVTKIVAQVFEDNKLPGAICSLTCGGADIGNAIAKDERVDLVSFTGSTNVGKQVALKVQERFGRKLLELGGNNAIIVFEDADLSLVTPSVLFAAVGTAGQRCTTARRLFLHESIHDEIVEKLSKAYAQVRIGDPCAPDTLCGPLHTKQAVEMYLSAVEQAKCEGGTVVCGGKVIDRPGNFVEPTIMTGLAHDAAIVHKETFAPILYVIKFKTEEEAFAWNNEVKQGLSSSIFTKDLGRIFRVTLPMSSLPCITLLAPFKNTGSDCGLVNVNIPTSGAEIGGAFGGEKHTGGGRESGSDSWKHYMRRST 514          

Query:  118 FNLSKSFF----RSNQRFSCYMIQSPEYSWLKDLGLKDYNNGVYDGNNWTASGTEFEQLCPSNNKIIAKIKMSSLEDCNRCIAETYKTNKVWR-NLPAPYRGEIVRQIGYRFRQKKDIIAKLLSLEVGKIYAEGKGEVQEIIDICDFATGLSRMFNGSIFPSE-------RQNHLLLEQWNPLGVVGVISAFNFPAAVFGWNLALALVCGNSVVWKGAPSTNLTTIAVSNIIIEVLKENNLPTSIVTALCGGTDVGQALVADKRIALVSFTGSCSAGAKVQQAVTNRFGRCLLELGGNNAIIVNHDANIDMVTRSVLFAAAGTAGQRCTTTRRLLVHEDVYDLVLSKLIAAYKKLRIGDPMDENVTIGPLHTKGAVEMFKNCIDQVKSSXXXXXXXXXXXXXXXNFVQPTIVTNLAHDHPIVHNETFVPIIYVIKIKNLDQAITINNEVEQGLSSSLFTRDLSSIYRWLGPEGSDCGLVNVNIPTNGAEIGGAFGGEKMTGGGRESGSDSWKQYMRRST 1638
            F L +  F    R +   S  +I  PEYSWLK+LGLK+ N GVY+G  W   G      CP NN  IA++K            + Y  N ++   +PAP RGEIVRQIG   R+K  ++  L SLE+GKI  EG GEVQE +DICD+A GLSR+  G I PSE       R  H L+EQWNP+G+VG+I+AFNFP AV+GWN ALAL+CGNSV+      T L    +  I+ +V ++N LP +I +  CGG D+G A+  D+R+ LVSFTGS + G +V   V  RFGR LLELGGNNAIIV  DA++ +VT SVLFAA GTAGQRCTT RRL +HE ++D ++ KL  AY ++RIGDP   +   GPLHTK AVEM+ + ++Q K  GG +  GG+ I   GNFV+PTI+T LAHD  IVH ETF PI+YVIK K  ++A   NNEV+QGLSSS+FT+DL  I+RWLGP+GSDCGLVNVNIPT+GAEIGGAFGGEK TGGGRESGSDSWK YMRRST
Sbjct:   12 FVLKRKIFASCCRQSAAMSSLLINQPEYSWLKELGLKEDNEGVYNGT-WGGKGEVVTSYCPGNNAPIARVK------------QYYLLNFIFFFQIPAPKRGEIVRQIGDALRKKIKLLGHLESLEMGKILVEGVGEVQEYVDICDYAVGLSRIIGGPILPSESNGVHVRRPGHALIEQWNPVGLVGIITAFNFPVAVYGWNNALALICGNSVL----ECTALILSVIDRIVAQVFEDNKLPGAICSLTCGGADIGNAIAKDERVDLVSFTGSTNVGKQVALKVQERFGRKLLELGGNNAIIVFEDADLSLVTPSVLFAAVGTAGQRCTTARRLFLHESIHDEIVEKLSKAYAQVRIGDPCAPDTLCGPLHTKQAVEMYLSAVEQAKCEGGTVVCGGKVIDRPGNFVEPTIMTGLAHDAAIVHKETFAPILYVIKFKTEEEAFAWNNEVKQGLSSSIFTKDLGRIFRWLGPKGSDCGLVNVNIPTSGAEIGGAFGGEKHTGGGRESGSDSWKHYMRRST 513          

Query:  118 FNLSKSFF----RSNQRFSCYMIQSPEYSWLKDLGLKDYNNGVYDGNNWTASGTEFEQLCPSNNKIIAKIKMSSLEDCNRCIAETYKTNKVWR-NLPAPYRGEIVRQIGYRFRQKKDIIAKLLSLEVGKIYAEGKGEVQEIIDICDFATGLSRMFNGSIFPSERQNHLLLEQWNPLGVVGVISAFNFPAAVFGWNLALALVCGNSVVWKGAPSTNLTTIAVSNIIIEVLKENNLPTSIVTALCGGTDVGQALVADKRIALVSFTGSCSAGAKVQQAVTNRFGRCLLELGGNNAIIVNHDANIDMVTRSVLFAAAGTAGQRCTTTRRLLVHEDVYDLVLSKLIAAYKKLRIGDPMDENVTIGPLHTKGAVEMFKNCIDQVKSSXXXXXXXXXXXXXXXNFVQPTIVTNLAHDHPIVHNETFVPIIYVIKIKNLDQAITINNEVEQGLSSSLFTRDLSSIYRWLGPEGSDCGLVNVNIPTNGAEIGGAFGGEKMTGGGRESGSDSWKQYMRRST 1638
            F L +  F    R +   S  +I  PEYSWLK+LGLK+ N GVY+G  W   G      CP NN  IA++K            + Y  N ++   +PAP RGEIVRQIG   R+K  ++  L SLE+GKI  EG GEVQE +DICD+A GLSR+  G I PSER  H L+EQWNP+G+VG+I+AFNFP AV+GWN ALAL+CGN  +WKGAP+T+LT++AV+ I+ +V ++N LP +I +  CGG D+G A+  D+R+ LVSFTGS + G +V   V  RF              V  DA++ +VT SVLFAA GTAGQRCTT RRL +HE ++D ++ KL  AY ++RIGDP D     GPLHTK AVEM+ + ++Q K  GG +  GG+ I   GNFV+PTI+T LAHD  IVH ETF PI+YVIK K  ++A   NNEV+QGLSSS+FT+DL  I+RWLGP+GSDCGLVNVNIPT+GAEIGGAFGGEK TGGGRESGSDSWK YMRRST
Sbjct:   12 FVLKRKIFASCCRQSAAMSSLLINQPEYSWLKELGLKEDNEGVYNGT-WGGKGEVVTSYCPGNNAPIARVK------------QYYLLNFIFFFQIPAPKRGEIVRQIGDALRKKIKLLGHLESLEMGKILVEGVGEVQEYVDICDYAVGLSRIIGGPILPSERPGHALIEQWNPVGLVGIITAFNFPVAVYGWNNALALICGNVCLWKGAPTTSLTSVAVTKIVAQVFEDNKLPGAICSLTCGGADIGNAIAKDERVDLVSFTGSTNVGKQVALKVQERF--------------VFEDADLSLVTPSVLFAAVGTAGQRCTTARRLFLHESIHDEIVEKLSKAYAQVRIGDPSD--TLCGPLHTKQAVEMYLSAVEQAKCEGGTVVCGGKVIDRPGNFVEPTIMTGLAHDAAIVHKETFAPILYVIKFKTEEEAFAWNNEVKQGLSSSIFTKDLGRIFRWLGPKGSDCGLVNVNIPTSGAEIGGAFGGEKHTGGGRESGSDSWKHYMRRST 494          

Query:  121 NLSKSFFRSNQRFSCYMIQSPEYSWLKDLGLKDYNNGVYDGNNWTASGTEFEQLCPSNNKIIAKIKMSSLEDCNRCIAETYKTNKVWRNLPAPYRGEIVRQIGYRFRQKKDIIAKLLSLEVGKIYAEGKGEVQEIIDICDFATGLSRMFNGSIFPSERQNHLLLEQWNPLGVVGVISAFNFPAAVFGWNLALALVCGNSVVWKGAPSTNLTTIAVSNIIIEVLKENNLPTSIVTALCGGTDVGQALVADKRIALVSFTGSCSAGAKVQQAVTNRFGRCLLELGGNNAIIVNHDANIDMVTRSVLFAAAGTAGQRCTTTRRLLVHEDVYDLVLSKLIAAYKKLRIGDPMDENVTIGPLHTKGAVEMFKNCIDQVKSSXXXXXXXXXXXXXXXNFVQPTIVTNLAHDHPIVHNETFVPIIYVIKIKNLDQAITINNEVEQGLSSSLFTRDLSSIYRWLGPEGSDCGLVNVNIPTNGAEIGGAFGGEKMTGGGRESGSDSWKQYMRRSTCTINCGTDLPLAQGIVFE 1692
             LS  + R     S  +I  P+Y+WL+DLGL++ N GVY+G+ W   G      CP+NN+ IA+++ +SL+D    I +  K   +W ++PAP RGEIVR+IG  FR+K  ++ +L+SLE+GKI  EG GEVQE +D+CD+A GLSRM  G   PSER  H L+E WNPLG+VG+I+AFNFP AVFGWN A+AL+ GN  +WKGAP+T+L ++AV+ II +VL++N LP +I + +CGG D+G  +  D+R+ L+SFTGS   G +V   V  RFG+ LLELGGNNAII   DA++ +V  SVLFAA GTAGQRCTT RRL +HE +++ V+ +L +AY ++R+G+P D N+  GPLHTK AV MF   +++ K  GG + +GG+ +   GN+V+PTIVT LAHD PIVH ETF PI+YV K ++ ++    NNEV+QGLSSS+FT+DL  I+RWLGP+GSDCG+VNVNIPT+GAEIGGAFGGEK TGGGRESGSD+WKQYMRRSTCTIN  T LPLAQGI F+
Sbjct:   17 KLSGPWSRPAAHMSTLLIHHPQYAWLQDLGLREDNEGVYNGS-WGGRGEVITTYCPANNEPIARVRQASLKDYEETIGKAKKAWNIWADIPAPKRGEIVRKIGDAFREKIQLLGRLVSLEMGKILVEGIGEVQEYVDVCDYAAGLSRMIGGPTLPSERPGHALIEMWNPLGLVGIITAFNFPVAVFGWNNAIALITGNVCLWKGAPTTSLVSVAVTKIIAQVLEDNLLPGAICSLVCGGADIGTTMARDERVNLLSFTGSTQVGKEVALMVQERFGKSLLELGGNNAIIAFEDADLSLVVPSVLFAAVGTAGQRCTTVRRLFLHESIHNEVVDRLRSAYSQIRVGNPWDPNILYGPLHTKQAVSMFVRAVEEAKKQGGTVVYGGKVMDHPGNYVEPTIVTGLAHDAPIVHQETFAPILYVFKFQDEEEVFEWNNEVKQGLSSSIFTKDLGRIFRWLGPKGSDCGIVNVNIPTSGAEIGGAFGGEKHTGGGRESGSDAWKQYMRRSTCTINYSTSLPLAQGIKFQ 539          

Query:  157 FSCYMIQSPEYSWLKDLGLKDYNNGVYDGNNWTASGTEFEQLCPSNNKIIAKIKMSSLEDCNRCIAETYKTNKVWRNLPAPYRGEIVRQIGYRFRQKKDIIAKLLSLEVGKIYAEGKGEVQEIIDICDFATGLSRMFNGSIFPSERQNHLLLEQWNPLGVVGVISAFNFPAAVFGWNLALALVCGNSVVWKGAPSTNLTTIAVSNIIIEVLKENNLPTSIVTALCGGTDVGQALVADKRIALVSFTGSCSAGAKVQQAVTNRFGRCLLELGGNNAIIVNHDANIDMVTRSVLFAAAGTAGQRCTTTRRLLVHEDVYDLVLSKLIAAYKKLRIGDPMDENVTIGPLHTKGAVEMFKNCIDQVKSSXXXXXXXXXXXXXXXNFVQPTIVTNLAHDHPIVHNETFVPIIYVIKIKNLDQAITINNEVEQGLSSSLFTRDLSSIYRWLGPEGSDCGLVNVNIPTNGAEIGGAFGGEKMTGGGRESGSDSWKQYMRRSTCTINCGTDLPLAQGIVFE 1692
             S  +I  P+Y+WL+DLGL++ N GVY+G+ W   G      CP+NN+ IA+++ +SL+D    I +  K   +W ++PAP RGEIVR+IG  FR+K  ++ +L+SLE+GKI  EG GEVQE +D+CD+A GLSRM  G   PSER  H L+E WNPLG+VG+I+AFNFP AVFGWN A+AL+ GN  +WKGAP+T+L ++AV+ II +VL++N LP +I + +CGG D+G  +  D+R+ L+SFTGS   G +V   V  RFG+ LLELGGNNAII   DA++ +V  SVLFAA GTAGQRCTT RRL +HE +++ V+ +L +AY ++R+G+P D N+  GPLHTK AV MF   +++ K  GG + +GG+ +   GN+V+PTIVT LAHD PIVH ETF PI+YV K ++ ++    NNEV+QGLSSS+FT+DL  I+RWLGP+GSDCG+VNVNIPT+GAEIGGAFGGEK TGGGRESGSD+WKQYMRRSTCTIN  T LPLAQGI F+
Sbjct:    1 MSTLLIHHPQYAWLQDLGLREDNEGVYNGS-WGGRGEVITTYCPANNEPIARVRQASLKDYEETIGKAKKAWNIWADIPAPKRGEIVRKIGDAFREKIQLLGRLVSLEMGKILVEGIGEVQEYVDVCDYAAGLSRMIGGPTLPSERPGHALIEMWNPLGLVGIITAFNFPVAVFGWNNAIALITGNVCLWKGAPTTSLVSVAVTKIIAQVLEDNLLPGAICSLVCGGADIGTTMARDERVNLLSFTGSTQVGKEVALMVQERFGKSLLELGGNNAIIAFEDADLSLVVPSVLFAAVGTAGQRCTTVRRLFLHESIHNEVVDRLRSAYSQIRVGNPWDPNILYGPLHTKQAVSMFVRAVEEAKKQGGTVVYGGKVMDHPGNYVEPTIVTGLAHDAPIVHQETFAPILYVFKFQDEEEVFEWNNEVKQGLSSSIFTKDLGRIFRWLGPKGSDCGIVNVNIPTSGAEIGGAFGGEKHTGGGRESGSDAWKQYMRRSTCTINYSTSLPLAQGIKFQ 511          

Query:  121 NLSKSFFRSNQRFSCYMIQSPEYSWLKDLGLKDYNNGVYDGNNWTASGTEFEQLCPSNNKIIAKIKMSSLEDCNRCIAETYKTNKVWRNLPAPYRGEIVRQIGYRFRQKKDIIAKLLSLEVGKIYAEGKGEVQEIIDICDFATGLSRMFNGSIFPSERQNHLLLEQWNPLGVVGVISAFNFPAAVFGWNLALALVCGNSVVWKGAPSTNLTTIAVSNIIIEVLKENNLPTSIVTALCGGTDVGQALVADKRIALVSFTGSCSAGAKVQQAVTNRFGRCLLELGGNNAIIVNHDANIDMVTRSVLFAAAGTAGQRCTTTRRLLV 1089
             LS  + R     S  +I  P+Y+WL+DLGL++ N GVY+G+ W   G      CP+NN+ IA+++ +SL+D    I +  K   +W ++PAP RGEIVR+IG  FR+K  ++ +L+SLE+GKI  EG GEVQE +D+CD+A GLSRM  G   PSER  H L+E WNPLG+VG+I+AFNFP AVFGWN A+AL+ GN  +WKGAP+T+L ++AV+ II +VL++N LP +I + +CGG D+G  +  D+R+ L+SFTGS   G +V   V  RFG+ LLELGGNNAII   DA++ +V  SVLFAA GTAGQRCTT RRL++
Sbjct:   17 KLSGPWSRPAAHMSTLLIHHPQYAWLQDLGLREDNEGVYNGS-WGGRGEVITTYCPANNEPIARVRQASLKDYEETIGKAKKAWNIWADIPAPKRGEIVRKIGDAFREKIQLLGRLVSLEMGKILVEGIGEVQEYVDVCDYAAGLSRMIGGPTLPSERPGHALIEMWNPLGLVGIITAFNFPVAVFGWNNAIALITGNVCLWKGAPTTSLVSVAVTKIIAQVLEDNLLPGAICSLVCGGADIGTTMARDERVNLLSFTGSTQVGKEVALMVQERFGKSLLELGGNNAIIAFEDADLSLVVPSVLFAAVGTAGQRCTTVRRLVM 338          

Query: 1294 NFVQPTIVTNLAHDHPIVHNETFVPIIYVIKIKNLDQAITINNEVEQGLSSSLFTRDLSSIYRWLGPEGSDCGLVNVNIPTNGAEIGGAFGGEKMTGGGRESGSDSWKQYMRRSTCTINCGTDLPLAQGIVFE 1692
            N+V+PTIVT LAHD PIVH ETF PI+YV K ++ ++    NNEV+QGLSSS+FT+DL  I+RWLGP+GSDCG+VNVNIPT+GAEIGGAFGGEK TGGGRESGSD+WKQYMRRSTCTIN  T LPLAQGI F+
Sbjct:  343 NYVEPTIVTGLAHDAPIVHQETFAPILYVFKFQDEEEVFEWNNEVKQGLSSSIFTKDLGRIFRWLGPKGSDCGIVNVNIPTSGAEIGGAFGGEKHTGGGRESGSDAWKQYMRRSTCTINYSTSLPLAQGIKFQ 475          

Query:  121 NLSKSFFRSNQRFSCYMIQSPEYSWLKDLGLKDYNNGVYDGNNWTASGTEFEQLCPSNNKIIAKIKMSSLEDCNRCIAETYKTNKVWRNLPAPYRGEIVRQIGYRFRQKKDIIAKLLSLEVGKIYAEGKGEVQEIIDICDFATGLSRMFNGSIFPSERQNHLLLEQWNPLGVVGVISAFNFPAAVFGWNLALALVCGNSVVWKGAPSTNLTTIAVSNIIIEVLKENNLPTSIVTALCGGTDVGQALVADKRIALVSFTGSCSAGAK 918
             LS  + R     S  +I  P+Y+WL+DLGL++ N GVY+G+ W   G      CP+NN+ IA+++ +SL+D    I +  K   +W ++PAP RGEIVR+IG  FR+K  ++ +L+SLE+GKI  EG GEVQE +D+CD+A GLSRM  G   PSER  H L+E WNPLG+VG+I+AFNFP AVFGWN A+AL+ GN  +WKGAP+T+L ++AV+ II +VL++N LP +I + +CGG D+G  +  D+R+ L+SFTGS   G +
Sbjct:   15 KLSGPWSRPAAHMSTLLIHHPQYAWLQDLGLREDNEGVYNGS-WGGRGEVITTYCPANNEPIARVRQASLKDYEETIGKAKKAWNIWADIPAPKRGEIVRKIGDAFREKIQLLGRLVSLEMGKILVEGIGEVQEYVDVCDYAAGLSRMIGGPTLPSERPGHALIEMWNPLGLVGIITAFNFPVAVFGWNNAIALITGNVCLWKGAPTTSLVSVAVTKIIAQVLEDNLLPGAICSLVCGGADIGTTMARDERVNLLSFTGSTQVGKE 279          

Query:  232 VYDGNNW--TASGTEFEQLCPSNNKIIAKIKMSSLEDCNRCIAET---YKTNKVWRNLPAPYRGEIVRQIGYRFRQKKDIIAKLLSLEVGKIYAEGKG-EVQEIIDICDFATGLSRMFNGSIFPSERQNHLLLEQWNPLGVVGVISAFNFPAAVFGWNLALALVCGNSVVWKGAPSTNLTTIAVSNIIIEVLKENNLPTSIVTALCG-GTDVGQALVADKRIALVSFTGSCSAGAKVQQAVT-NRFGRCLLELGGNNAIIVNHDANIDMVTRSVLFAAAGTAGQRCTTTRRLLVHEDVYDLVLSKLIAAYKKLRIGDPMDENVTIGPLHTKGAVEMFKNCIDQVKSSXXXXXXXXXXXXXXXNFVQPTIVTNLAHDHPIVHNETFVPIIYVIKIKNLDQAITINNEVEQGLSSSLFTRDLSSIYRWLGPEGSDCGLVNVNIPTNGAEIGGAFGGEKMTGGGRESGSDSWKQYMRRSTCTIN 1650
            ++  N+W  + SG +F    PS  + I +++     D ++ +      ++    WR L A  RG+++ Q+     + + I+A L +++ GK +      +++  I    +  G +    G   P++  N +   +  P+GV G I+ +NFP  +  W LA AL CGN+VV K A  T LT + ++++I EV      P  +V  + G G  VG A+ +  +I  ++FTGS   G  V++A + +   R  LELGG N  IV  DA++D+             GQ CT   R+ V E VY   + + +   KK  +GDP D     GP   +   +     I+  K  G K+E GG  +   G F++PT+ +++  +  I   E F P+  ++K KNL++ I   N  + GL++++FT++L    +       + G V +N   N       FGG KM+G GRE G  +  +Y    T TI 
Sbjct:   34 IFINNDWHESKSGRKFATYNPSTLEKICEVEEGDKPDVDKAVEAAQAAFQRGSPWRRLDALSRGQLLHQLADLVERDRAILATLETMDTGKPFLHAFFVDLEGCIKTFRYFAGWADKIQGRTIPTD-DNVVCFTRHEPIGVCGAITPWNFPLLMLAWKLAPALCCGNTVVLKPAEQTPLTALYLASLIKEV----GFPPGVVNIVPGFGPTVGAAISSHPQINKIAFTGSTEVGKLVREAASRSNLKRVTLELGGKNPCIVCADADLDLAVECAHQGVFFNQGQCCTAASRVFVEEQVYGEFVRRSVEFAKKRPVGDPFDAKTEQGPQIDQKQFDKILELIESGKKEGAKLECGGSAMEDRGLFIKPTVFSDVTDNMRIAKEEIFGPVQPILKFKNLEEVIKRANSTDYGLTAAVFTKNLDKALKLAA--ALESGTVWINC-YNAFYAQAPFGGFKMSGNGRELGEYALAEYTEVKTVTIK 506          

Query:  121 NLSKSFFRSNQRFSCYMIQSPEYSWLKDLGLKDYNNGVYDGNNWTASGTEFEQLCPSNNKIIAKIKMSSLEDCNRCIAETYKTNKVWRNLPAPYRGEIVRQIGYRFRQKKDIIAKLLSLEVGKIYAEGKGEVQEIIDICDFATGLSRMFNGSIFPSERQNHLLLEQWNPLGVVGVISAFNFPAAVFGWNLALALVCGNSVVWKGAPSTNLTTIAVSNIIIEVLKENNLPTSIVTALCGGTDVGQALVADKRIALVSFTGSCSAGAKVQQAVTNRFGRCLLELGGNNAIIVNHDANIDMVTRSVLFAAAGTAGQRCTTTRRLLVHEDVYDLVLSKLIAAYKKLRIGDPMDENVTIGPLHTKGAVEMFKNCIDQVKSSXXXXXXXXXXXXXXXNFVQPTIVTNLAHDHPIVHNETFVPIIYVIKIKNLDQAITINNEVEQGLSSSLFTRDLSSIYRWLGPEGSDCGLVNVNIPTNGAEIGGAFGGEKMTGGGRESGSDSWKQYMRRSTCTINCGTDLPLAQGIVFE 1692
              S S+ R     S  +I  P+Y+WLK+LGL++ N+GVY+G+ W   G      CP+NN+ IA+++ +S+ D    + +  +   +W ++PAP RGE+VRQIG   R+K  ++  L+SLE+GKI  EG GEVQE +D+CD+A GLSRM  G I PSER  H L+EQWNP+G+VG+I+AFNFP AV+GWN A+A++CGN+ +WKGAP+T+L ++AV+ II +VL++N LP +I +  CGG D+G A+  D+R+ L+SFTGS   G +V   V  RFGR LLELGGNNAII   DA++ +V  S LFAA GTAGQRCTT RRL +HE ++D V+++L  AY ++R+G+P D NV  GPLHTK AV MF   +++ K  GG + +GG+ +   GN+V+PTIVT L HD  IVH ETF PI+YV K KN D+    NNEV+QGLSSS+FT+D+  I+RWLGP+GSDCG+VNVNIPT+GAEIGGAFGGEK TGGGRESGSD+WKQYMRRSTCTIN   DLPLAQGI F+
Sbjct:   17 KFSGSWNRPAAFMSTLLINQPQYAWLKELGLREENDGVYNGS-WGGRGEVITTYCPANNEPIARVRQASMADYEETVEKAREAWSIWADVPAPKRGEVVRQIGDALREKIQVLGSLVSLEMGKILVEGVGEVQEYVDVCDYAVGLSRMIGGPILPSERPGHALIEQWNPVGLVGIITAFNFPVAVYGWNNAIAMICGNACLWKGAPTTSLISVAVTKIIAKVLEDNKLPGAICSLTCGGADIGTAMAKDERVDLLSFTGSTQVGKQVALMVQERFGRSLLELGGNNAIIAFEDADLSLVVPSALFAAVGTAGQRCTTARRLFLHESIHDEVVNRLKKAYAQIRVGNPWDSNVLYGPLHTKQAVSMFLGAVEEAKKEGGTVVYGGKVMDRPGNYVEPTIVTGLDHDASIVHTETFAPILYVFKFKNEDEVFAWNNEVKQGLSSSIFTKDMGRIFRWLGPKGSDCGIVNVNIPTSGAEIGGAFGGEKHTGGGRESGSDAWKQYMRRSTCTINYSKDLPLAQGIKFQ 539          

Query:  121 NLSKSFFRSNQRFSCYMIQSPEYSWLKDLGLKDYNNGVYDGNNWTASGTEFEQLCPSNNKIIAKIKMSSLEDCNRCIAETYKTNKVWRNLPAPYRGEIVRQIGYRFRQKKDIIAKLLSLEVGKIYAEGKGEVQEIIDICDFATGLSRMFNGSIFPSERQNHLLLEQWNPLGVVGVISAFNFPAAVFGWNLALALVCGNSVVWKGAPSTNLTTIAVSNIIIEVLKENNLPTSIVTALCGGTDVGQALVADKRIALVSFTGSCSAGAKVQQAVTNRFGRCLLELGGNNAIIVNHDANIDMVTRSVLFAAAGTAGQRCTTTRRLLVHEDVYDLVLSKLIAAYKKLRIGDPMDENVTIGPLHTKGAVEMFKNCIDQVKSSXXXXXXXXXXXXXXXNFVQPTIVTNLAHDHPIVHNETFVPIIYVIKIKNLDQAITINNEVEQGLSSSLFTRDLSSIYRWLGPEGSDCGLVNVNIPTNGAEIGGAFGGEKMTGGGRESGSDSWKQYMRRSTCTINCGTDLPLAQGIVFE 1692
             LS  + R     S  +I  P+Y+WLK+LGL++ N GVY+G+ W   G      CP+NN+ IA+++ +S+ D    + +  +  K+W ++PAP RGEIVRQIG   R+K  ++  L+SLE+GKI  EG GEVQE +DICD+A GLSRM  G I PSER  H L+EQWNP+G+VG+I+AFNFP AV+GWN A+A++CGN  +WKGAP+T+L ++AV+ II +VL++N LP +I +  CGG D+G A+  D+R+ L+SFTGS   G +V   V  RFGR LLELGGNNAII   DA++ +V  S LFAA GTAGQRCTT RRL +HE ++D V+++L  AY ++R+G+P D NV  GPLHTK AV MF   +++ K  GG + +GG+ +   GN+V+PTIVT L HD  I H ETF PI+YV K KN ++    NNEV+QGLSSS+FT+DL  I+RWLGP+GSDCG+VNVNIPT+GAEIGGAFGGEK TGGGRESGSD+WKQYMRRSTCTIN   DLPLAQGI F+
Sbjct:   17 KLSGPWSRPAAFMSTLLINQPQYAWLKELGLREENEGVYNGS-WGGRGEVITTYCPANNEPIARVRQASVADYEETVKKAREAWKIWADIPAPKRGEIVRQIGDALREKIQVLGSLVSLEMGKILVEGVGEVQEYVDICDYAVGLSRMIGGPILPSERSGHALIEQWNPVGLVGIITAFNFPVAVYGWNNAIAMICGNVCLWKGAPTTSLISVAVTKIIAKVLEDNKLPGAICSLTCGGADIGTAMAKDERVNLLSFTGSTQVGKQVGLMVQERFGRSLLELGGNNAIIAFEDADLSLVVPSALFAAVGTAGQRCTTARRLFIHESIHDEVVNRLKKAYAQIRVGNPWDPNVLYGPLHTKQAVSMFLGAVEEAKKEGGTVVYGGKVMDRPGNYVEPTIVTGLGHDASIAHTETFAPILYVFKFKNEEEVFAWNNEVKQGLSSSIFTKDLGRIFRWLGPKGSDCGIVNVNIPTSGAEIGGAFGGEKHTGGGRESGSDAWKQYMRRSTCTINYSKDLPLAQGIKFQ 539          

Query:  121 NLSKSFFRSNQRFSCYMIQSPEYSWLKDLGLKDYNNGVYDGNNWTASGTEFEQLCPSNNKIIAKIKMSSLEDCNRCIAETYKTNKVWRNLPAPYRGEIVRQIGYRFRQKKDIIAKLLSLEVGKIYAEGKGEVQEIIDICDFATGLSRMFNGSIFPSERQNHLLLEQWNPLGVVGVISAFNFPAAVFGWNLALALVCGNSVVWKGAPSTNLTTIAVSNIIIEVLKENNLPTSIVTALCGGTDVGQALVADKRIALVSFTGSCSAGAKVQQAVTNRFGRCLLELGGNNAIIVNHDANIDMVTRSVLFAAAGTAGQRCTTTRRLLVHEDVYDLVLSKLIAAYKKLRIGDPMDENVTIGPLHTKGAVEMFKNCIDQVKSSXXXXXXXXXXXXXXXNFVQPTIVTNLAHDHPIVHNETFVPIIYVIKIKNLDQAITINNEVEQGLSSSLFTRDLSSIYRWLGPEGSDCGLVNVNIPTNGAEIGGAFGGEKMTGGGRESGSDSWKQYMRRSTCTINCGTDLPLAQGIVFE 1692
             LS  + R     S  +I  P+Y+WL+DLGL++ N GVY+G+ W   G      CP+NN+ IA+++ +SL+D    I +  K   +W ++PAP RGEIVR+IG  FR+K  ++ +L+SLE+GKI  EG GEVQE +D+CD+A GLSRM  G   PSER  H L+E WNPLG+VG+I+AFNFP AVFGWN A+AL+ GN  +WKGAP+T+L ++AV+ II +VL++N LP +I + +CGG D+G  +  D+R+ L+SFTGS   G +V   V  RFG+ LLELGGNNAII   DA++ +V  SVLFAA GTAGQRCTT RRL +HE +++ V+ +L +AY ++R+G+P D N+  GPLHTK AV MF   +++ K  GG + +GG+ +   GN+V+PTIVT LAHD PIVH ETF PI+YV K ++ ++    NNEV+QGLSSS+FT+DL  I+RWLGP+GSDCG+VNVNIPT+GAEIGGAFGGEK TGGGRESGSD+WKQYMRRSTCTIN  T LPLAQGI F+
Sbjct:   17 KLSGPWSRPAAHMSTLLIHHPQYAWLQDLGLREDNEGVYNGS-WGGRGEVITTYCPANNEPIARVRQASLKDYEETIGKAKKAWNIWADIPAPKRGEIVRKIGDAFREKIQLLGRLVSLEMGKILVEGIGEVQEYVDVCDYAAGLSRMIGGPTLPSERPGHALIEMWNPLGLVGIITAFNFPVAVFGWNNAIALITGNVCLWKGAPTTSLVSVAVTKIIAQVLEDNLLPGAICSLVCGGADIGTTMARDERVNLLSFTGSTQVGKEVALMVQERFGKSLLELGGNNAIIAFEDADLSLVVPSVLFAAVGTAGQRCTTVRRLFLHESIHNEVVDRLRSAYSQIRVGNPWDPNILYGPLHTKQAVSMFVRAVEEAKKQGGTVVYGGKVMDHPGNYVEPTIVTGLAHDAPIVHQETFAPILYVFKFQDEEEVFEWNNEVKQGLSSSIFTKDLGRIFRWLGPKGSDCGIVNVNIPTSGAEIGGAFGGEKHTGGGRESGSDAWKQYMRRSTCTINYSTSLPLAQGIKFQ 539          

Query:  121 NLSKSFFRSNQRFSCYMIQSPEYSWLKDLGLKDYNNGVYDGNNWTASGTEFEQLCPSNNKIIAKIKMSSLEDCNRCIAETYKTNKVWRNLPAPYRGEIVRQIGYRFRQKKDIIAKLLSLEVGKIYAEGKGEVQEIIDICDFATGLSRMFNGSIFPSERQNHLLLEQWNPLGVVGVISAFNFPAAVFGWNLALALVCGNSVVWKGAPSTNLTTIAVSNIIIEVLKENNLPTSIVTALCGGTDVGQALVADKRIALVSFTGSCSAGAKVQQAVTNRFGRCLLELGGNNAIIVNHDANIDMVTRSVLFAAAGTAGQRCTTTRRLLVHEDVYDLVLSKLIAAYKKLRIGDPMDENVTIGPLHTKGAVEMFKNCIDQVKSSXXXXXXXXXXXXXXXNFVQPTIVTNLAHDHPIVHNETFVPIIYVIKIKNLDQAITINNEVEQGLSSSLFTRDLSSIYRWLGPEGSDCGLVNVNIPTNGAEIGGAFGGEKMTGGGRESGSDSWKQYMRRSTCTINCGTDLPLAQGIVFE 1692
             LS+ + R     S  +I  P+Y+WL+DLGL++ N GV++G+ W   G      CP+NN+ IA+++ +S++D    I +  K   +W ++PAP RGEIVR+IG   R+K  ++ +L+SLE+GKI  EG GEVQE +D+CD+A GLSRM  G   PSER  H L+EQWNPLG+VG+I+AFNFP AVFGWN A+AL+ GN  +WKGAP+T+L +IAV+ II +VL++N LP +I +  CGG D+G A+  D+R+ L+SFTGS   G +V   V  RFG+ LLELGGNNAII   DA++ +V  S LFAA GTAGQRCTT RRL +HE ++D V+ +L  AY ++R+G+P D N+  GPLHTK AV MF   +++ K  GG + +GG+ +   GN+V+PTIVT L HD PIVH ETF PI+YV K KN ++    NNEV+QGLSSS+FT+DL  I+RWLGP+GSDCG+VNVNIPT+GAEIGGAFGGEK TGGGRESGSD+WKQYMRRSTCTIN  T LPLAQGI F+
Sbjct:   17 KLSRLWSRPAALMSTLLIHHPQYAWLQDLGLREDNEGVFNGS-WGGRGEVITTYCPANNEPIARVRQASMKDYEETIGKAKKAWNIWADIPAPKRGEIVRKIGDALREKIQLLGRLVSLEMGKILVEGIGEVQEYVDVCDYAAGLSRMIGGPTLPSERPGHALMEQWNPLGLVGIITAFNFPVAVFGWNNAIALITGNVCLWKGAPTTSLVSIAVTKIIAKVLEDNLLPGAICSLTCGGADMGTAMARDERVNLLSFTGSTQVGKQVALMVQERFGKSLLELGGNNAIIAFEDADLSLVLPSALFAAVGTAGQRCTTVRRLFLHESIHDEVVDRLKNAYSQIRVGNPWDPNILYGPLHTKQAVSMFVQAVEEAKKEGGTVVYGGKVMDHPGNYVEPTIVTGLVHDAPIVHKETFAPILYVFKFKNEEEVFEWNNEVKQGLSSSIFTKDLGRIFRWLGPKGSDCGIVNVNIPTSGAEIGGAFGGEKHTGGGRESGSDAWKQYMRRSTCTINYSTALPLAQGIKFQ 539          

Query:  160 SCYMIQSPEYSWLKDLGLKDYNNGVYDGNNWTASGTEFEQLCPSNNKIIAKIKMSSLEDCNRCIAETYKTNKVWRNLPAPYRGEIVRQIGYRFRQKKDIIAKLLSLEVGKIYAEGKGEVQEIIDICDFATGLSRMFNGSIFPSERQNHLLLEQWNPLGVVGVISAFNFPAAVFGWNLALALVCGNSVVWKGAPSTNLTTIAVSNIIIEVLKENNLPTSIVTALCGGTDVGQALVADKRIALVSFTGSCSAGAKVQQAVTNRFGRCLLELGGNNAIIVNHDANIDMVTRSVLFAAAGTAGQRCTTTRRLLVHEDVYDLVLSKLIAAYKKL--RIGDPMDENVTIGPLHTKGAVEMFKNCIDQVKSSXXXXXXXXXXXXXXXNFVQPTIVTNLAHDHPIVHNETFVPIIYVIKIKNLDQAITINNEVEQGLSSSLFTRDLSSIYRWLGPEGSDCGLVNVNIPTNGAEIGGAFGGEKMTGGGRESGSDSWKQYMRRSTCTINCGTDLPLAQGIVFE 1692
            S  +I   +Y +LK+LGL + N GV+ G  W ASG   +   P+NN  IA ++  +++D    I+E  K    W  +PAP RGEIVRQIG + R +   + KL+SLE+GKI AEG GEVQE +DICD+ATGLSR   G IFPSER  H LLEQWNPLGVVGVISAFNFP AV+GWN ALALV GNSVVWK APST LT IAV+ ++ EVL  NN+  ++ + +CG  DVGQALV DKR+ LVSFTGS   G  V Q V  RFG+ LLELGGNNAIIVN DA+++MV  + +FAA GTAGQRCTTTRRL+VH+ VYD VL +L  AY +   RIG P+D N  IGPLH + AV  +K  + +  +SGGKIE+GG+ +  +GNFV PTIVT L HD P+V  ETF PI+YV+K   L++AI INNEV+QGLSSSLFT ++ ++++W+GP+GSDCG+VNVNIPT+GAEIGGAFGGEK TGGGRESGSDSW+QYMRRSTCTIN   +LPLAQGI FE
Sbjct:   20 SQLLINDSKYGFLKELGLTENNAGVFHGK-WAASGQVVQSFAPANNSPIANVQNGNVQDYEIAISEAKKAYNDWCEVPAPRRGEIVRQIGDKLRTQLQNLGKLVSLEMGKISAEGVGEVQEYVDICDYATGLSRSLEGKIFPSERPGHALLEQWNPLGVVGVISAFNFPCAVYGWNNALALVTGNSVVWKPAPSTPLTAIAVTKLVEEVLVANNVNPALCSLVCGEGDVGQALVKDKRVNLVSFTGSSEIGKIVGQQVQARFGKLLLELGGNNAIIVNEDADLNMVVPATVFAAVGTAGQRCTTTRRLIVHDKVYDQVLERLKKAYAQFESRIGCPLDSNTIIGPLHNQQAVGKYKASVAEAVASGGKIEYGGKVLERDGNFVLPTIVTGLKHDSPVVLRETFAPILYVLKFSTLEEAIAINNEVDQGLSSSLFTTNIQNVFKWMGPKGSDCGIVNVNIPTSGAEIGGAFGGEKETGGGRESGSDSWRQYMRRSTCTINYSKELPLAQGIKFE 531          

Query:  160 SCYMIQSPEYSWLKDLGLKDYNNGVYDGNNWTASGTEFEQLCPSNNKIIAKIKMSSLEDCNRCIAETYKTNKVWRNLPAPYRGEIVRQIGYRFRQKKDIIAKLLSLEVGKIYAEGKGEVQEIIDICDFATGLSRMFNGSIFPSERQNHLLLEQWNPLGVVGVISAFNFPAAVFGWNLALALVCGNSVVWKGAPSTNLTTIAVSNIIIEVLKENNLPTSIVTALCGGTDVGQALVADKRIALVSFTGSCSAGAKVQQAVTNRFGRCLLELGGNNAIIVNHDANIDMVTRSVLFAAAGTAGQRCTTTRRLLVHEDVYDLVLSKLIAAYKK--LRIGDPMDENVTIGPLHTKGAVEMFKNCIDQVKSSXXXXXXXXXXXXXXXNFVQPTIVTNLAHDHPIVHNETFVPIIYVIKIKNLDQAITINNEVEQGLSSSLFTRDLSSIYRWLGPEGSDCGLVNVNIPTNGAEIGGAFGGEKMTGGGRESGSDSWKQYMRRSTCTINCGTDLPLAQGIVFE 1692
            S  +I++P+YSWLKDLGL+  N GV+ G  WT +G      CP+NN+ IA++   ++ED + CI    K    W ++PAP RGEIVRQ+G   R KK+++ KL+SLE+GKI +EG GE+QE IDICD+A GLSRMF+G I PSER  H+LLE WNPLGVVGVI+AFNFPAAVFGWN A+ALVCGN+ +WKGAP+T LT+IAV+ ++ EVL++NN+P SI + +CGG DVGQA+  D RI LVSFTGSCS G KV   VT RFGR LLELGGNNAIIVN DA++DMV R+ LFA  GTAGQRCTTTRRL++HE ++D V+ +L  +Y++  LR GDP++ N   GP+H+K  V+ F++ I    S GGKIEFGG+ +   GN+V+PTIVTNL+HD PIVH ETF PI+YV+K+K+LD+AI  NNEVEQGLSSSLFT+D+ +IY WLGP+GSDCG+VNVNIPTNGAEIGGAFGGEK TGGGRESGSDSWKQYMRRSTCTIN G +LPLAQGI FE
Sbjct:    5 SLLLIENPKYSWLKDLGLQSENPGVFHGK-WTGNGKVVTSECPANNQPIARVTEGNIEDYDNCITAAQKAWADWADVPAPQRGEIVRQLGNALRDKKELLGKLVSLEMGKILSEGAGEIQEYIDICDYAVGLSRMFSGKIIPSERPKHILLENWNPLGVVGVITAFNFPAAVFGWNNAIALVCGNTTLWKGAPTTPLTSIAVTKVVQEVLEKNNMPPSICSMICGGADVGQAMAKDPRIPLVSFTGSCSIGQKVAVEVTRRFGRRLLELGGNNAIIVNEDADLDMVVRAALFACMGTAGQRCTTTRRLILHEKIHDAVVERLKKSYEQVVLRTGDPLEGNTLYGPMHSKQGVQQFQSAIQTAISLGGKIEFGGKVMDRPGNYVEPTIVTNLSHDSPIVHQETFAPIVYVLKVKSLDEAIRWNNEVEQGLSSSLFTKDVGAIYNWLGPKGSDCGIVNVNIPTNGAEIGGAFGGEKHTGGGRESGSDSWKQYMRRSTCTINYGRELPLAQGIKFE 516          

Query:  103 LAPFL-------FNLSKSFFRSNQRFSC---YMIQSPEYSWLKDLGLKDYNNGVYDGNNWTASGTEFEQLCPSNNKIIAKIKMSSLEDCNRCIAETYKTNKVWRNLPAPYRGEIVRQIGYRFRQKKDIIAKLLSLEVGKIYAEGKGEVQEIIDICDFATGLSRMFNGSIFPSERQNHLLLEQWNPLGVVGVISAFNFPAAVFGWNLALALVCGNSVVWKGAPSTNLTTIAVSNIIIEVLKENNLPTSIVTALCGGTDVGQALVADKRIALVSFTGSCSAGAKVQQAVTNRFGRCLLELGGNNAIIVNHDANIDMVTRSVLFAAAGTAGQRCTTTRRLLVHEDVYDLVLSKLIAAYKKLRIGDPMDENVTIGPLHTKGAVEMFKNCIDQVKSSXXXXXXXXXXXXXXXNFVQPTIVTNLAHDHPIVHNETFVPIIYVIKIKNLDQAITINNEVEQGLSSSLFTRDLSSIYRWLGPEGSDCGLVNVNIPTNGAEIGGAFGGEKMTGGGRESGSDSWKQYMRRSTCTINCGTDLPLAQGIVFE 1692
            +AP L       F+L ++F  S++ +S    +++  P+YSWLKDLG+   N GVY G  W  SG E    CP+NNK IA++   +  D    +  +      W +LP P RGEIVRQIG  FR KK ++ KL++LE+GKI AEG+GEVQE+IDICD+A GLSRMF G +FPSER+ HLLLEQWNPLGVVGVI+AFNFP AV+GWN +LALVCGN+++WKGAPST L ++A++ II EVL  N +P  +   + GG D+G  +  D+R+ L+SFTGS   G KV   V  RFG+ LLELGGNNAI+VN DA++DMV RS LFA AGTAGQRCTTTRRL++HE V+D ++ +L  AY  LR+GDP++E+   GPLH + AV+ FK  ++  K+ GG +  GG+ +  EGN+V+PTIVT LAHD PIV  ETFVPI+YV+K KN+D+A+  NNEV+QGLSSSLFT+DLS+I++W+GP+GSDCG+VNVNIPT+GAEIGGAFGGEK TGGGRESGSD+WKQY+RRSTCT+N   +LPLAQGI FE
Sbjct:    1 MAPLLGVRLCRGFSLYRTFVSSSRYYSAMANFLVDDPKYSWLKDLGISSQNQGVYHGK-WCGSGQEVTTYCPANNKPIAQVTTGNAADYETAVQASLTAWDHWADLPGPQRGEIVRQIGEAFRDKKHLLGKLIALEMGKIAAEGEGEVQELIDICDYAVGLSRMFAGHVFPSERKGHLLLEQWNPLGVVGVITAFNFPCAVYGWNASLALVCGNTMLWKGAPSTPLVSVAMTKIISEVLDRNKIPGGVCALVSGGADIGTLMAKDERVKLLSFTGSTPVGHKVSMMVQERFGKFLLELGGNNAIVVNEDADVDMVVRSALFACAGTAGQRCTTTRRLILHEKVHDEIVERLSKAYSLLRVGDPIEEDTLYGPLHNQEAVDKFKAAVEAAKAQGGTVVCGGKVMDREGNYVEPTIVTGLAHDAPIVLQETFVPIVYVLKCKNVDEAMAWNNEVKQGLSSSLFTKDLSAIFKWMGPKGSDCGIVNVNIPTSGAEIGGAFGGEKHTGGGRESGSDAWKQYVRRSTCTLNFSKELPLAQGIKFE 539          

Query:  139 FRSNQRFSCYMIQSPEYSWLKDLGLKDYNNGVYDGNNWTASGTEFEQLCPSNNKIIAKIKMSSLEDCNRCIAETYKTNKVWRNLPAPYRGEIVRQIGYRFRQKKDIIAKLLSLEVGKIYAEGKGEVQEIIDICDFATGLSRMFNGSIFPSERQNHLLLEQWNPLGVVGVISAFNFPAAVFGWNLALALVCGNSVVWKGAPSTNLTTIAVSNIIIEVLKENNLPTSIVTALCGGTDVGQALVADKRIALVSFTGSCSAGAKVQQAVTNRFGRCLLELGGNNAIIVNHDANIDMVTRSVLFAAAGTAGQRCTTTRRLLVHEDVYDLVLSKLIAAYKKLRIGDPMDENVTIGPLHTKGAVEMFKNCIDQVKSSXXXXXXXXXXXXXXXNFVQPTIVTNLAHDHPIVHNETFVPIIYVIKIKNLDQAITINNEVEQGLSSSLFTRDLSSIYRWLGPEGSDCGLVNVNIPTNGAEIGGAFGGEKMTGGGRESGSDSWKQYMRRSTCTINCGTDLPLAQGIVFE 1692
            +R ++  S  +I  P+YSWLK+LGLK+ N+GVY+G  W   G      CP+NN+ IA+++ +++ +    + +  +  K+W ++PAP RGEIVRQIG   R++  ++  L+SLE+GKIY EG GEVQE +D+CD+A GLSRM  G + PSER  H L+EQWNP+G+VG+I+AFNFP AV+GWN A+AL+CGN  +WKGAP+T LT++AV+ I+  VL++NNLP +I +  CGG D+G+AL  D+R+ LVSFTGS   G KV   V  RFGR LLELGGNNAIIV  DA++++V  S +FA+ GTAGQRCTTTRRL++HE V+D V++++  AYK++RIGDP D N   GPLHTK AVE +K  +DQ K  GG I +GG+ +   GN+V+PTI+T LAHD PIV  ETFVPI+YV+K K+ ++A T NNEV+QGLSSS+FT+D+  ++RWLGP+GSDCG+VNVNIPT+GAEIGGAFGGEK TGGGRESGSDSWKQYMRRSTCTIN   DLPLAQGI FE
Sbjct:   96 YRQSRTMSTLLINQPKYSWLKELGLKEENDGVYNGT-WGGKGEVVTSYCPANNEPIARVRQATMAEYEETVQKAKEAWKIWADIPAPKRGEIVRQIGDALRKQIKVLGSLVSLEMGKIYVEGVGEVQEYVDVCDYAVGLSRMIGGPVLPSERPGHALIEQWNPVGLVGIITAFNFPVAVYGWNNAIALICGNVCLWKGAPTTPLTSVAVTKIVAGVLEQNNLPGAICSMTCGGADIGEALAKDERVGLVSFTGSTHVGKKVSLMVQERFGRQLLELGGNNAIIVFEDADLNLVVPSAVFASVGTAGQRCTTTRRLMLHESVHDDVVARIAKAYKQIRIGDPWDPNTLYGPLHTKQAVEQYKQALDQAKQQGGTIVYGGKVMDRPGNYVEPTIITGLAHDAPIVQTETFVPILYVLKFKSEEEAFTWNNEVKQGLSSSIFTKDMGRVFRWLGPKGSDCGIVNVNIPTSGAEIGGAFGGEKHTGGGRESGSDSWKQYMRRSTCTINYSKDLPLAQGIKFE 612          

Query:  103 LAPFLFNLSKSF--FRSNQRFSCYMIQSPEYSWLKDLGLKDYNNGVYDGNNWTASGTEFEQLCPSNNKIIAKIKMSSLEDCNRCIAETYKTNKVWRNLPAPYRGEIVRQIGYRFRQKKDIIAKLLSLEVGKIYAEGKGEVQEIIDICDFATGLSRMFNGSIFPSERQNHLLLEQWNPLGVVGVISAFNFPAAVFGWNLALALVCGNSVVWKGAPSTNLTTIAVSNIIIEVLKENNLPTSIVTALCGGTDVGQALVADKRIALVSFTGSCSAGAKVQQAVTNRFGRCLLELGGNNAIIVNHDANIDMVTRSVLFAAAGTAGQRCTTTRRLLVHEDVYDLVLSKLIAAYKKLRIGDPMDENVTIGPLHTKGAVEMFKNCIDQVKSSXXXXXXXXXXXXXXXNFVQPTIVTNLAHDHPIVHNETFVPIIYVIKIKNLDQAITINNEVEQGLSSSLFTRDLSSIYRWLGPEGSDCGLVNVNIPTNGAEIGGAFGGEKMTGGGRESGSDSWKQYMRRSTCTINCGTDLPLAQGIVFE 1692
            LA  L    K+F  +R +   S  +IQ P+Y+WLK+LGLK+ N+GV++G+ W   G      CP+NN+ IA+++ ++LED    + +  +  KVW ++PAP RGEIVRQIG   R+K  ++  L+SLE+GKI  EG GEVQE IDICD+A GLSRMF G + PSER  H L+EQWNPLG+VG+I+AFNFP AV+GWN ALALVCGN  +WKGAP+T LT++AV+ I+ +VL++N LP +I +  CGGTD+G A+  D+RI L+SFTGS + G +V   V  RFGR LLELGGNNAIIV  DA+++MV  SVLFAA GTAGQRCTTTRRL +HE ++D V+ +L+ AYK++RIGDP+D     GPLHTK AV+M+KN ++Q K  GG +  GG+ I   GN+V+PTIVT L HD  IVH ETF PI+YV+K K+ ++A   NNEV+QGLSSS+FT+D+  ++RW+GP+GSDCG+VNVNIPT+GAEIGGAFGGEK TGGGRESGSD+WK YMRRSTCTIN   +LPLAQGI FE
Sbjct:    8 LARPLLRGKKAFCGWRLSAAMSSLLIQRPDYAWLKELGLKEDNSGVFNGS-WGGRGEVVTSYCPANNEPIARVRQATLEDYEETVRKAKEAWKVWADIPAPKRGEIVRQIGDALRKKLKVLGNLVSLEMGKISVEGVGEVQEYIDICDYAVGLSRMFGGPVLPSERPGHALIEQWNPLGLVGIITAFNFPVAVYGWNNALALVCGNCCLWKGAPTTPLTSVAVTQIVAQVLEDNKLPGAICSLTCGGTDIGAAMSKDERINLLSFTGSTNVGKQVSLVVQERFGRLLLELGGNNAIIVFDDADLNMVIPSVLFAAVGTAGQRCTTTRRLFLHESIHDGVVERLVKAYKQVRIGDPLDSTTLYGPLHTKQAVDMYKNAVEQAKQQGGTVACGGKVINRPGNYVEPTIVTGLPHDASIVHTETFAPILYVLKFKSEEEAFAWNNEVKQGLSSSIFTKDVGRMFRWMGPKGSDCGIVNVNIPTSGAEIGGAFGGEKHTGGGRESGSDAWKHYMRRSTCTINYSKELPLAQGIKFE 538          

Query:   79 SFIKKMSYLAPFLFNLSKSFFRSNQRFSCYMIQSPEYSWLKDLGLKDYNNGVYDGNNWTASGTEFEQLCPSNNKIIAKIKMSSLEDCNRCIAETYKTNKVWRNLPAPYRGEIVRQIGYRFRQKKDIIAKLLSLEVGKIYAEGKGEVQEIIDICDFATGLSRMFNGSIFPSERQNHLLLEQWNPLGVVGVISAFNFPAAVFGWNLALALVCGNSVVWKGAPSTNLTTIAVSNIIIEVLKENNLPTSIVTALCGGTDVGQALVADKRIALVSFTGSCSAGAKVQQAVTNRFGRCLLELGGNNAIIVNHDANIDMVTRSVLFAAAGTAGQRCTTTRRLLVHEDVYDLVLSKLIAAYKKLRIGDPMDENVTIGPLHTKGAVEMFKNCIDQVKSSXXXXXXXXXXXXXXXNFVQPTIVTNLAHDHPIVHNETFVPIIYVIKIKNLDQAITINNEVEQGLSSSLFTRDLSSIYRWLGPEGSDCGLVNVNIPTNGAEIGGAFGGEKMTGGGRESGSDSWKQYMRRSTCTINCGTDLPLAQGIVFE 1692
            + ++    +A  L   + +F    +  S  +I  P+YSWLKDLGL   N GV+ G  WT SG      CP+NN+ IA++   S  D +  +    +  + W  +PAP RGEIVRQIG+  R+KK ++ KL SLE GKI  EG+GEVQE IDICD+A GLSRMF G + PSER  HLLLEQWNPLGVVGVI+AFNFP AVFGWN ++AL CGN  +WKGAPST LT+IAV+ ++  VL+ NN+P ++V+ +CGG D+G  +  D+RI LVSFTGS   G  V Q VT RFG+ +LELGGNNAIIVN DA++DMV R+ LFA  GTAGQRCTTTRRL+VHE +YD VLS L  AY ++++GDP++    +GP+H+K  VE++   +  V++ GGKIE GG+ +   GNFV+PTIVT L HD  IVH ETF PI+Y++K K+L++ I  NNEV+QGLSSSLFTRD+S++++W+GP+GSDCGL+NVNIPT+GAEIGGAFGGEK TGGGRESGSD+WKQYMRR+TCTINC  +LPLAQGI FE
Sbjct:    3 AILRTSRTVAYSLIKRTLTFKTPYRAMSSLLIDDPKYSWLKDLGLSADNKGVFHGV-WTGSGEVTTSYCPTNNQPIARVTQGSPGDYDSAVKAALEAWQTWCEVPAPQRGEIVRQIGHALREKKTLLGKLESLENGKILPEGEGEVQEFIDICDYAVGLSRMFQGLVLPSERPGHLLLEQWNPLGVVGVITAFNFPVAVFGWNSSIALTCGNVALWKGAPSTPLTSIAVTRVMTSVLEANNMPPAVVSLVCGGADIGTLMAKDERIPLVSFTGSTPVGHIVAQMVTERFGKKILELGGNNAIIVNEDADVDMVVRASLFACVGTAGQRCTTTRRLIVHEKLYDAVLSGLKKAYGQVKMGDPLEPGTLLGPMHSKQGVELYLKAVADVQAQGGKIEVGGKAVDRPGNFVEPTIVTGLPHDAEIVHRETFAPIVYIMKCKSLEEGIQWNNEVKQGLSSSLFTRDISNVFKWIGPKGSDCGLINVNIPTSGAEIGGAFGGEKHTGGGRESGSDAWKQYMRRATCTINCSRELPLAQGIKFE 539          

Query:  139 FRSNQRFSCYMIQSPEYSWLKDLGLKDYNNGVYDGNNWTASGTEFEQLCPSNNKIIAKIKMSSLEDCNRCIAETYKTNKVWRNLPAPYRGEIVRQIGYRFRQKKDIIAKLLSLEVGKIYAEGKGEVQEIIDICDFATGLSRMFNGSIFPSERQNHLLLEQWNPLGVVGVISAFNFPAAVFGWNLALALVCGNSVVWKGAPSTNLTTIAVSNIIIEVLKENNLPTSIVTALCGGTDVGQALVADKRIALVSFTGSCSAGAKVQQAVTNRFGRCLLELGGNNAIIVNHDANIDMVTRSVLFAAAGTAGQRCTTTRRLLVHEDVYDLVLSKLIAAYKKLRIGDPMDENVTIGPLHTKGAVEMFKNCIDQVKSSXXXXXXXXXXXXXXXNFVQPTIVTNLAHDHPIVHNETFVPIIYVIKIKNLDQAITINNEVEQGLSSSLFTRDLSSIYRWLGPEGSDCGLVNVNIPTNGAEIGGAFGGEKMTGGGRESGSDSWKQYMRRSTCTINCGTDLPLAQGIVFE 1692
            F+ +   S  +I  P+Y+WLK+LGL + N+GVY+G  W   G      CP+NN+ IA+++ ++L +    + +  +  KVW ++PAP RGEIVRQIG   R+K  ++  L+SLE+GKIY EG GEVQE +D+CD+A GLSRM  G + PSER  H L+EQWNP+G+VG+I+AFNFP AV+GWN A+AL+CGN  +WKGAP+T LT++AV+ I+ EVL++NNLP +I +  CGG D+G AL  D+R+ LVSFTGS   G +V   V  RFGR LLELGGNNAIIV  DA++++V  S LFA+ GTAGQRCTTTRRL++HE V+D V+ +L  AYK++RIGDP D +   GPLHTK AV+ +   I+Q K  GG +  GG+ +   GN+V+PTI T LAHD PIVH ETFVPI+YVIK K  ++A   NNEV+QGLSSS+FT+D+  ++RWLGP+GSDCG+VNVNIPT+GAEIGGAFGGEK TGGGRESGSDSWKQYMRRSTCTIN   DLPLAQGI FE
Sbjct:   24 FQPSAAMSTLLINQPKYAWLKELGLSEDNDGVYNGT-WGGKGEVVTSYCPANNEPIARVRQATLAEYEETVQKAREAWKVWADIPAPKRGEIVRQIGDALRKKIKVLGSLVSLEMGKIYVEGVGEVQEYVDVCDYAVGLSRMIGGPVLPSERPGHALIEQWNPVGLVGIITAFNFPVAVYGWNNAIALICGNVCLWKGAPTTPLTSVAVTKIVAEVLEQNNLPGAICSMTCGGADIGTALSKDERVDLVSFTGSTQVGKQVALMVQERFGRQLLELGGNNAIIVFEDADLNLVVPSALFASVGTAGQRCTTTRRLMLHESVHDEVVERLSKAYKQVRIGDPWDPSTLYGPLHTKHAVQQYLAAIEQAKQQGGTLVCGGKVMDRPGNYVEPTIFTGLAHDAPIVHTETFVPILYVIKFKTEEEAFAWNNEVKQGLSSSIFTKDMGRVFRWLGPKGSDCGIVNVNIPTSGAEIGGAFGGEKHTGGGRESGSDSWKQYMRRSTCTINYSKDLPLAQGIKFE 540          

Query:  139 FRSNQRFSCYMIQSPEYSWLKDLGLKDYNNGVYDGNNWTASGTEFEQLCPSNNKIIAKIKMSSLEDCNRCIAETYKTNKVWRNLPAPYRGEIVRQIGYRFRQKKDIIAKLLSLEVGKIYAEGKGEVQEIIDICDFATGLSRMFNGSIFPSERQNHLLLEQWNPLGVVGVISAFNFPAAVFGWNLALALVCGNSVVWKGAPSTNLTTIAVSNIIIEVLKENNLPTSIVTALCGGTDVGQALVADKRIALVSFTGSCSAGAKVQQAVTNRFGRCLLELGGNNAIIVNHDANIDMVTRSVLFAAAGTAGQRCTTTRRLLVHEDVYDLVLSKLIAAYKKLRIGDPMDENVTIGPLHTKGAVEMFKNCIDQVKSSXXXXXXXXXXXXXXXNFVQPTIVTNLAHDHPIVHNETFVPIIYVIKIKNLDQAITINNEVEQGLSSSLFTRDLSSIYRWLGPEGSDCGLVNVNIPTNGAEIGGAFGGEKMTGGGRESGSDSWKQYMRRSTCTINCGTDLPLAQGIVFE 1692
            F+ +   S  +I  P+Y+WLK+LGL + N+GVY+G  W   G                                         +PAP RGEIVRQIG   R+K  ++  L+SLE+GKIY EG GEVQE +D+CD+A GLSRM  G + PSE  +H L+EQWNP+G+VG+I+AFNFP AV+GWN A+AL+CGN  +WKGAP+T LT++AV+ I+ EVL++NNLP +I +  CGG D+G AL  D+R+ LVSFTGS   G +V   V  RFGR LLELGGNNAIIV  DA++++V  S LFA+ GTAGQRCTTTRRL++HE V+D V+ +L  AYK++RIGDP D +   GPLHTK AV+ +   I+Q K  GG +  GG+ +   GN+V+PTI T LAHD PIVH ETFVPI+YVIK K  ++A   NNEV+QGLSSS+FT+D+  ++RWLGP+GSDCG+VNVNIPT+GAEIGGAFGGEK TGGGRESGSDSWKQYMRRSTCTIN   DLPLAQGI FE
Sbjct:   24 FQPSAAMSTLLINQPKYAWLKELGLSEDNDGVYNGT-WGGKG----------------------------------------EIPAPKRGEIVRQIGDALRKKIKVLGSLVSLEMGKIYVEGVGEVQEYVDVCDYAVGLSRMIGGPVLPSE--SHALIEQWNPVGLVGIITAFNFPVAVYGWNNAIALICGNVCLWKGAPTTPLTSVAVTKIVAEVLEQNNLPGAICSMTCGGADIGTALSKDERVDLVSFTGSTQVGKQVALMVQERFGRQLLELGGNNAIIVFEDADLNLVVPSALFASVGTAGQRCTTTRRLMLHESVHDEVVERLSKAYKQVRIGDPWDPSTLYGPLHTKHAVQQYLAAIEQAKQQGGTLVCGGKVMDRPGNYVEPTIFTGLAHDAPIVHTETFVPILYVIKFKTEEEAFAWNNEVKQGLSSSIFTKDMGRVFRWLGPKGSDCGIVNVNIPTSGAEIGGAFGGEKHTGGGRESGSDSWKQYMRRSTCTINYSKDLPLAQGIKFE 498          

Query:  223 NNGVYDGNNW--TASGTEFEQLCPSNNKIIAKIKMSSLEDCNRCIAET---YKTNKVWRNLPAPYRGEIVRQIGYRFRQKKDIIAKLLSLEVGKIYAEGKG-EVQEIIDICDFATGLSRMFNGSIFPSERQNHLLLEQWNPLGVVGVISAFNFPAAVFGWNLALALVCGNSVVWKGAPSTNLTTIAVSNIIIEVLKENNLPTSIVTALCG-GTDVGQALVADKRIALVSFTGSCSAGAKVQQAVT-NRFGRCLLELGGNNAIIVNHDANIDMVTRSVLFAAAGTAGQRCTTTRRLLVHEDVYDLVLSKLIAAYKKLRIGDPMDENVTIGPLHTKGAVEMFKNCIDQVKSSXXXXXXXXXXXXXXXNFVQPTIVTNLAHDHPIVHNETFVPIIYVIKIKNLDQAITINNEVEQGLSSSLFTRDLSSIYRWLGPEGS-DCGLVNVNIPTNGAEIGGAFGGEKMTGGGRESGSDSWKQYMRRSTCTINCGTDLPL 1671
            N  ++  N W  +A G       P+    I +++ +   D +  +       K    WR +    RG ++ ++     + + ++A + S++ GK + +    +++  I    +  G +   +G   P +  N +   +  P+GV G I  +NFP  +F W +A AL CGN+VV K +  T LT + V  +I    KE   P  +V  + G G   G A+ +   I  V+FTGS   G  +++A   +   R  LELGG N  IV  D+++ +  +     A    GQ CT   R+ V E VYD  +   + + KK+  GDPMD   + GP   +   E   + ++  K  G K+E GG  +  +G F+QPTI +++     +   E F P+  ++K K+ ++ I   N    GL++++FTR   S+ R +    + + G V VN   N       FGG KM+G GRE G  +  +Y      TI     L L
Sbjct:    6 NIQLFINNEWHSSAKGKTIPIFNPATGDKICEVEEADKADVDVAVEAARAAMKRGSAWRRMDVSGRGRLLHKLAELLERDRTLLATMESMDSGKPFLQSFFIDLEGSIKTLRYYAGWADKIHGKTMPVD-DNFMCFTKHEPVGVCGAIIPWNFPLLMFTWKIAPALCCGNTVVIKPSELTPLTALHVGALI----KEAGFPPGVVNIVPGFGPTSGAAIASHMGIDKVAFTGSVEVGQLIKEAAAKSNLKRVTLELGGKNPCIVFGDSDLQLAVQEAQKGAFYNQGQCCTAASRVFVEERVYDEFVRLSVESAKKIVAGDPMDPRTSHGPQINQQQFEKILDLVESGKREGAKLECGGHALQDKGLFIQPTIFSDVKDHMRLAKEEIFGPVQCIMKFKSQEEVIERANSTHYGLAAAVFTR---SVDRAMSVSSALEAGTVWVNC-YNALHAQAPFGGYKMSGNGRELGEYALAEYTEVKAVTIKLSEQLTL 488          

Query:  244 NNW--TASGTEFEQLCPSNNKIIAKIKMSSLEDCNRCIAET---YKTNKVWRNLPAPYRGEIVRQIGYRFRQKKDIIAKLLSLEVGKIYAEGKG-EVQEIIDICDFATGLSRMFNGSIFPSERQNHLLLEQWNPLGVVGVISAFNFPAAVFGWNLALALVCGNSVVWKGAPSTNLTTIAVSNIIIEVLKENNLPTSIVTALCG-GTDVGQALVADKRIALVSFTGSCSAGAKVQQAVT-NRFGRCLLELGGNNAIIVNHDANIDMVTRSVLFAAAGTAGQRCTTTRRLLVHEDVYDLVLSKLIAAYKKLRIGDPMDENVTIGPLHTKGAVEMFKNCIDQVKSSXXXXXXXXXXXXXXXNFVQPTIVTNLAHDHPIVHNETFVPIIYVIKIKNLDQAITINNEVEQGLSSSLFTRDLSSIYRWLGPEGS-DCGLVNVNIPTNGAEIGGAFGGEKMTGGGRESGSDSWKQYMRRSTCTINCGTDLPL 1671
            N W  +A G       P+    I +++ +   D +  +       K    WR +    RG ++ ++     + + ++A + S++ GK + +    +++  I    +  G +   +G   P +  N +   +  P+GV G I  +NFP  +F W +A AL CGN+VV K +  T LT + V  +I    KE   P  +V  + G G   G A+ +   I  V+FTGS   G  +++A   +   R  LELGG N  IV  D+++ +  +     A    GQ CT   R+ V E VYD  +   + + KK+  GDPMD   + GP   +   E   + ++  K  G K+E GG  +  +G F+QPTI +++     +   E F P+  ++K K+ ++ I   N    GL++++FTR   S+ R +    + + G V VN   N       FGG KM+G GRE G  +  +Y      TI     L L
Sbjct:   38 NEWHSSAKGKTIPIFNPATGDKICEVEEADKADVDVAVEAARAAMKRGSAWRRMDVSGRGRLLHKLAELLERDRTLLATMESMDSGKPFLQSFFIDLEGSIKTLRYYAGWADKIHGKTMPVD-DNFMCFTKHEPVGVCGAIIPWNFPLLMFTWKIAPALCCGNTVVIKPSELTPLTALHVGALI----KEAGFPPGVVNIVPGFGPTSGAAIASHMGIDKVAFTGSVEVGQLIKEAAAKSNLKRVTLELGGKNPCIVFGDSDLQLAVQEAQKGAFYNQGQCCTAASRVFVEERVYDEFVRLSVESAKKIVAGDPMDPRTSHGPQINQQQFEKILDLVESGKREGAKLECGGHALQDKGLFIQPTIFSDVKDHMRLAKEEIFGPVQCIMKFKSQEEVIERANSTHYGLAAAVFTR---SVDRAMSVSSALEAGTVWVNC-YNALHAQAPFGGYKMSGNGRELGEYALAEYTEVKAVTIKLSEQLTL 513          

Query:  232 VYDGNNW--TASGTEFEQLCPSNNKIIAKIKMSSLEDCNRCIA---ETYKTNKVWRNLPAPYRGEIVRQIGYRFRQKKDIIAKLLSLEVGKIYAEGKG-EVQEIIDICDFATGLSRMFNGSIFPSERQNHLLLEQWNPLGVVGVISAFNFPAAVFGWNLALALVCGNSVVWKGAPSTNLTTIAVSNIIIEVLKENNLPTSIVTALCG-GTDVGQALVADKRIALVSFTGSCSAGAKVQQAV-TNRFGRCLLELGGNNAIIVNHDANIDMVTRSVLFAAAGTAGQRCTTTRRLLVHEDVYDLVLSKLIAAYKKLRIGDPMDENVTIGPLHTKGAVEMFKNCIDQVKSSXXXXXXXXXXXXXXXN---FVQPTIVTNLAHDHPIVHNETFVPIIYVIKIKNLDQAITINNEVEQGLSSSLFTRDLSSIYRWLGPEGSDCGLVNVNIPTNGAEIGGAFGGEKMTGGGRESGSDSWKQYMRRSTCTIN 1650
            ++  N W  + SG  F    P+  + I  ++ +   D ++ +      +  +  WR + +  RG ++ ++     + +  +A L SL+ GK +      ++Q  I    +  G +   +G+  P++   +L   +  P+GV G I  +NFP  +  W L  AL CGN+VV K A  T LT + + ++I    KE   P  +V  L G G   G  + +   I  V+FTGS   G  +Q+A   +   R  LELGG N  I+  DA++D+            +GQ CT   R+ V E +YD  +S+ +   K+  +G P D     GP   + + E  +  ++ V+S   +            +   ++QPT+ +N+     I   E F P+  ++K K +++ I   N  E GL++++FT D+S             G V +N   N       FGG KM+G GRE G    ++Y    T T+ 
Sbjct:   41 IFINNEWHDSLSGKTFSTYNPATGEKICDVQEADKADVDKAVKAARSAFSLSSEWRRMDSSDRGRLLSKLADLVERDRLYLATLESLDTGKPFLSSFFVDLQGTIKTLRYFAGWADKIHGTSIPTD-GGYLSFTRHEPIGVCGQIIPWNFPLMMMAWKLGPALCCGNTVVMKPAEQTPLTCLYMGSLI----KEAGFPPGVVNILPGFGPTAGAGIASHMGIDKVAFTGSTKVGKLIQEAAGKSNLKRVTLELGGKNPNIIFADADLDLAVEQAHQGVFFNSGQCCTAGSRIFVEESIYDEFVSRSVERAKRRIVGSPFDPTTEQGP---QISAEQQRRVLEFVESGISEGAKLECGGKAHFSKGFYIQPTVFSNVQDHMRIAREEIFGPVQQIMKFKTMEEVIERANNTEYGLTAAVFTNDISKAMAI--STALQAGTVWINC-FNALSCQCPFGGFKMSGNGRELGEYGLREYTEVKTITVK 513          

Query:  139 FRSNQRFSCYMIQSPEYSWLKDLGLKDYNNGVYDGNNWTASGTEFEQLCPSNNKIIAKIKMSSLEDCNRCIAETYKTNKVWRNLPAPYRGEIVRQIGYRFRQKKDIIAKLLSLEVGKIYAEGKGEVQEIIDICDFATGLSRMFNGSIFPSERQNHLLLEQWNPLGVVGVISAFNFPAAVFGWNLALALVCGNSVVWKGAPSTNLTTIAVSNI--IIEVLKENNLPTSIVTALCGGTDVGQALVADKRIALVSFTGSCSAGAKVQQAVTNRFGRCLLELGGNNAIIVNHDANIDMVTRSVLFAAAGTAGQRCTTTRRLLVHEDVYDLVLSKLIAAYKKLRIGDPMDENVTIGPLHTKGAVEMFKNCIDQVKSSXXXXXXXXXXXXXXXNFVQPTIVTNLAHDHPIVHNETFVPIIYVIKIKNLDQAITINNEVEQGLSSSLFTRDLSSIYRWLGPEGSDCGLVNVNIPTNGAEIGGAFGGEKMTGGGRESGSDSWKQYMRRSTCTINCGTDLPLAQGIVFE 1692
             R     +  +I+ P+Y+WLK+LGL+  N+GVY+G  W   G       P+ N+ IA ++ ++L D    + +  +  KVW ++PAP RGEIVRQIG   R+K  ++  L+SLE+GKI  EG GEVQE +D+CD+A GLSRM  G + PSER  H L+EQWNP+G+VGVI+AFNFP AV+GWN ALALVCGN  +WKGAP+T LT++AV+ I  + EVL+ NNLP +I +   GG D+G A+  D+RI LVSFTGS   G +V   V  RFG  LLELGGNNAIIV  DA++++V  +VLFAA GTAGQRCTTTRRL++HE ++D V+  L+ AYK++RIGDP+D N   GPLHTK +VEM+K  ++Q    GG +E GG+ I   GNFV+PTI+T L HD  IVH ETF P++YV+K K  ++AI  NNEV+QGLSSS+FT+DL  I+ WLGP+GSDCG+VNVNIPT+GAEIGGAFGGEK TGGGRESGSDSWK YMRRSTCTIN   +LPLAQGI FE
Sbjct:   23 LRYLSAMASLLIEQPKYAWLKELGLRAENDGVYNGV-WGGRGELVTSYSPATNEPIAHVRQATLADYEDTVKKANEAWKVWADIPAPKRGEIVRQIGDALRKKIKVLGNLVSLEMGKIGVEGLGEVQEYVDVCDYAVGLSRMIGGPVLPSERPGHALIEQWNPVGLVGVITAFNFPVAVYGWNNALALVCGNCCLWKGAPTTPLTSVAVTRIRIVAEVLESNNLPGAICSLTTGGADIGTAIARDERIPLVSFTGSTPVGKQVALMVQERFGNKLLELGGNNAIIVMDDADLNLVIPAVLFAAVGTAGQRCTTTRRLILHESIHDKVVESLVKAYKQVRIGDPLDANTLYGPLHTKQSVEMYKAAVEQAVKQGGTVECGGKVIDRPGNFVEPTIITGLKHDAAIVHQETFAPVLYVLKFKAFEEAIAWNNEVKQGLSSSIFTQDLGRIFTWLGPKGSDCGIVNVNIPTSGAEIGGAFGGEKHTGGGRESGSDSWKHYMRRSTCTINYSKNLPLAQGIKFE 541          

Query:  253 TASGTEFEQLCPSNNKIIAKIKMSSLEDCNRCIAETYKT-NKVWRNLPAPYRGEIVRQIGYRFRQKKDIIAKLLSLEVGKIYAEGKGEVQEIIDICDFATGLSRMFNGS--IFPSERQNHLLLEQWNPLGVVGVISAFNFPAAVFGWNLALALVCGNSVVWKGAPSTNLTTIAVSNIIIEVLKENNLPTSIVTALCGGTDVGQALVADKRIALVSFTGSCSAGAKVQQAVTNRFGRCLLELGGNNAIIVNHDANIDMVTRSVLFAAAGTAGQRCTTTRRLLVHEDVYDLVLSKLIAAYKKLRIGDPMDENVTIGPLHTKGAVEMFKNCIDQVKSSXXXXXXXXXXXXXXXN------FVQPTIVTNLAHDHPIVHNETFVPIIYVIKIKNLDQAITINNEVEQGLSSSLFTRDLSSIYRWLGP-EGSDCGLVNVNIPTNGAEIGGAFGGEKMTGGGRESGSDSWKQYMRRSTCTINCG 1656
            +  G EF+ + P+   ++ + + S   D    + +  +     WR L    R + + +     +++++ +A +   + GK   E + +V       ++  GL+    G     P       +  +  PLGV   I A+NFP  +  W  A AL CGN++V+K +P T LT +A++    E+  E  LP  +   + G  + GQ L +   +A VS TGS   G KV Q    R     LELGG + +IV  D ++D   ++ L     + GQ C+   R+ V   V +  L +L+     +RIGDP  ++ T+G L ++  ++     + +    G K+  GG+    E        F+ P ++     D   V  E F P++ V+     ++ +   N  + GL++ +FT+DL+  +R +   +   C + N N+      +   FGG KM+G GRE+G  +   Y +  T  +  G
Sbjct:   53 STGGPEFDVVNPATGGLLCRGQASGAVDVQAAVKDAREAFEGSWRGLSGSERSQHLLRASAIIKERREELAVMEVKDTGKPVYEARMDVDSGWQCLEYFAGLAPTIAGQHIQLPG---GSFMYSRREPLGVCVGIGAWNFPFQIACWKSAPALACGNAMVFKPSPLTPLTAVALA----EIYTEAGLPPGLFNIVQGDGETGQLLCSHNDVAKVSCTGSVGTGVKVLQQTAPRIKPVTLELGGKSPLIVFSDCDLDNAVKAALMGNFLSQGQVCSNATRVFVQRSVCERFLERLLDRVSAIRIGDPQRDSTTMGALISQSHLDRVLAYVQRAVQEGAKLVCGGKKYVPEDPSLKGGFFMTPCVLAECRDDMQAVREEIFGPVMAVLAFDTEEEVLQRANATDFGLAAGVFTKDLTRAHRVIAALQAGSCYINNYNV----VLMEMPFGGYKMSGFGRENGMATVDYYTQLKTVYVEMG 519          

Query:  403 RGEIVRQIGYRFRQKKDIIAKLLSLEVGKIYAEGKGEVQEIIDICDFATGLSRMFNGSIFPSERQNHLLLEQWNPLGVVGVISAFNFPAAVFGWNLALALVCGNSVVWKGAPSTNLTTIAVSNIIIEVLKENNLPTSIVTAL-CGGTDV---GQALVADKRIALVSFTGSCSAGAKVQQAVTNRFGRCLLELGGNNAIIVNHDANIDMVTRSVLFAAAGTAGQRCTTTRRLLVHEDVYDLVLSKLI-AAYKKLRIGDPMDENVTIGPLHTKGAVEMFKNCIDQVKSSXXXXXXXXXXXXXXXNFVQPTIVTNLAHDHPIVHNETFVPIIYVIKIKNLDQAITINNEVEQGLSSSLFTRDLSSIYRWLGPEGSDCGLVNVNIPTNGAEIGGAFGGEKMTGGGRESGSDSWKQYMR 1629
            RG ++++      Q +  +A+L++ E GK   E  GEV       ++    +R   G I PS   +  +   + P+GV  +I+ +NFP A+    +  AL  G + V K A  T L+ +A++ + +E      LP  ++  + C   +V   G+ L     ++ +SFTGS + G  +         R  +ELGG+   IV   A++D   R +L +    +GQ C    R+LV E V+D  +S+L  A   +LR+G   D   T+GPL  + A+E  +  +    S G ++  GG      G+F QPT++ ++  +      ETF P+  +IK K  ++AI + N    GL+   F+RD++ ++R    E  + G+V  N     A +   FGG K +G GRE       +YM 
Sbjct:    3 RGALLKRWYEVILQNRQELAQLITAESGKPQQESLGEVSYGAAFLEWFGEEARRAYGQIIPSAAPDRRMFSMYQPVGVAAMITPWNFPVAMITRKVGAALAAGCTAVVKPAEDTPLSALALAQLAVEA----GLPPGVLNVVPCSRANVAAVGELLCTHPSVSKISFTGSTATGKVLMAHAVGTVKRVSMELGGHAPFIVFESADLDAAVRGLLSSKFRFSGQTCVCPNRMLVQESVHDAFVSRLAHAVSTQLRVGPGADTGNTLGPLINEHALEKVERHVVDAVSQGARVVVGGARHALGGSFFQPTVLADVTPNMLCAREETFGPLAPIIKFKTEEEAIALANSTAMGLAGYFFSRDVAQVWRV--SEALEVGMVGANEGLLSA-VEAPFGGIKQSGLGREGAQQGMLEYMH 409          

Query:  271 FEQLCPSNNKIIAKIKMSSLEDCNRCIAETYKT--NKVWRNLPAPYRGEIVRQIGYRFRQKKDIIAKLLSLEVGKIYAEG-KGEVQEIIDICDFATGLSRMFNGSIFP--SERQN-HLLLEQWNPLGVVGVISAFNFPAAVFGWNLALALVCGNSVVWKGAPSTNLTTIAVSNIIIEVLKENNLPTSIVTALCG--GTDVGQALVADKRIALVSFTGSCSAGAKVQQA-VTNRFGRCLLELGGNNAIIVNHDANIDMVTRSVLFAAAGTAGQRCTTTRRLLVHEDVYDLVLSKLIAAYKKLRIGDPMDENVTIGPLHTKGAVE-MFKNCIDQVKSSXXXXXXXXXXXXXXXNFVQPTIVTNLAHDHPIVHNETFVPIIYVIKIK--NLDQAITINNEVEQGLSSSLFTRDLS-SIYRWLGPEGSDCGLVNVNIPTNGAEIGGAFGGEKMTGGGRESGSDSWKQYMRRSTCTIN 1650
            ++ + P++  +I K+  +S+ D +  +A   +   +  W  +    RG ++ ++     + ++ +A + +L+ G +Y    K  V   I    +  G     +G+  P    R N +L   +  P+GV G++  +N+P  +  W  A  L  GN++V K A  T LT +  +    E+  +   P  ++  + G  G+ VGQ +     I  + FTGS   G ++ ++  T+   +  LELGG + +I+ +D +ID   R  + A     G+ C    RL V E ++D  + +++   KK+++GDP+D +   GP + +  +E + + C   VK     +  G +    E  F  P++ T +     I   E+F PI+ + K    ++D  +   N  E GL+S +FTRD+S ++Y     +  + G V +N   N  ++   FGG K +G G++ G ++  +Y+R    T+ 
Sbjct:  227 YDTVNPTDGSVICKVAFASVADVDEAVAAAKRAFESGEWGRMNPRDRGRLLYKLADLMEEHQEELATIETLDSGAVYTLALKTHVGMSIQTFRYFAGWCDKIHGTTIPINQARPNRNLTFTKREPIGVCGIVIPWNYPLMMLAWKSAACLAAGNTLVLKPAQVTPLTALKFA----ELAAKAGFPKGVINIIPGSVGSIVGQRMSEHPHIRKLGFTGSTPIGKQIMKSCATSNLKKVSLELGGKSPLIIFNDCDIDKAVRMGMSAVFFNKGENCIAAGRLFVEESIHDEYVRRVVEEIKKMKVGDPLDRSTDHGPQNHRAHMEKLVEYCEVGVKEGATLVHGGRQVPRPEV-FANPSVFTGVEDHMYIAQEESFGPIMVISKFPDGDIDGVLARANNTEFGLASGVFTRDISKALYV---SDQLEAGTVFINT-YNKTDVAAPFGGFKQSGFGKDLGEEALNEYLRTKAVTVE 690          

Query:  205 LGLKDYNNGVYDGNNWTASGTEFEQLCPSNNKIIAKIKMSSLEDCNRCIAETYKTNKVWRNLPAPYRGEIVRQIGYRFRQKKDIIAKLLSLEVGKIYAEGKG-EVQEIIDICDFATGLSRMFNGSI--FPSE--RQNHLLLEQW---NPLGVVGVISAFNFPAAVFGWNLALALVCGNSVVWKGAPSTNLTTIAVSNIIIEVLKENNLPTSIVTALCGGTDVGQALVADKRIALVSFTGSCSAGAKVQQAVTNRFGRCLLELGGNNAIIVNHDANIDM-VTRSVLFAAAGTAGQRCTTTRRLLVHEDVYDLVLSKLIAAYKKLRIGDPMDENVTIGPLHTK-------GAVEMFKNCIDQVKSSXXXXXXXXXXXXXXXNFVQPTIVTNLAHDHPIVHNETFVPIIYVIKIKNLDQAITINNEVEQGLSSSLFTRDLSSIYR-----WLGPEGSDCGLV-NVNIPTNGAEIGGAFGGEKMTGGGRESGSDSWKQYMRRSTCTIN 1650
            L L++Y NG      + AS T  +   PS   +  ++  S   + N  +    +    W       RG I+ ++       + I ++L  L + + + +GK  E    +DI   A    R F  ++  + +E  + +H+    +   +P+GVVG+IS +N P  +  W +A A+  GN+VV K +  T++T   +  ++ E          +   L  G   G ALV    +  +SFTGS +    +         R  LELGG N  ++  DA++D  V  +V  + A   G   ++   +  H  V      +     K  ++G P D    +GPL +K       G VE+ +    QV    G            G F+ PT++T +  D P +  E F P++ V   ++ D+A+T +N V  GL++ +++RD++ ++R       G   ++C L+  +N+P         FGG K +G GRE   DS++ +    T TI 
Sbjct:    8 LVLENYING-----EFVASETHVDSFEPSTGNVYCRVPDSGEAEVNAAVEAAKRAFPAWAARSPQERGRILTRLA------ELIESRLEELAIAESHDQGKTVEHARTVDIPRAAYNF-RFFASAVQHYTTECTQADHVGCMHYTVRSPVGVVGLISPWNLPLYLLTWKIAPAIALGNTVVAKPSELTSVTAWMLCMLLREAGVPP---GVVNVVLGTGQKAGAALVGHPDVPAISFTGSTATACDITVRSALHCKRLSLELGGKNPAVIFADADLDACVATTVRSSFANQTGHVPSSLSAIFSHSVVVQCP-RRFFRTTKAWKVGPPDDFTSNMGPLISKEHLAKVRGYVELAERDGGQVLCGEGVDPLLLPPRCQGGYFLAPTVITGVPDDSPAMQEEIFGPVVCVSPFEDEDEAVTRSNGVRYGLAAVVWSRDVARVHRVAKRLQAGIVWTNCWLIRELNLP---------FGGMKASGIGREGAKDSFEFFTDVKTITIK 486          

Query:  271 FEQLCPSNNKIIAKIKMSSLEDCNRCI--AETYKTNKVWRNLPAPYRGEIVRQIGYRFRQKKDIIAKLLSLEVGKIYAEGKGEVQEIIDICDFATGLSRMFNGSIFPSERQNHLLLEQWNPLGVVGVISAFNFPAAVFGWNLALALVCGNSVVWKGAPSTNLTTIAVSNIIIEVLKENNLPTSIVTALCG-GTDVGQALVADKRIALVSFTGSCSAGAKVQQAVTNRFGRCLLELGGNNAIIVNHDANIDMVTRSVLFAAAGTAGQRCTTTRRLLVHEDVYDLVLSKLIAAYKKLRIGDPMDENVTIGPLHTKGAVEMFKNCIDQVKSSXXXXXXXXXXXXXXXNFVQPTIVTNLAHDHPIVHNETFVPIIYVIKIKNLDQAITINNEVEQGLSSSLFTRDLSSIYRWLGPEGSDCGLVNVNIPTNGAEIGGAFGGEKMTGGGRESGSDSWKQYMR 1629
            FE + PS  + I  I     +D    +  A+   +N  W  +    RG+ + ++     Q KD+IA + +L+ GK  +  +G+V  +I+    + G +   +G +  + R  H    +  PLGV G I  +NFP  ++ W +A ALV GN+VV K A ST L+ + VS  I     +  +P  ++  + G G  VG+A+    +I  V+FTGS + G  + Q+      +  LELGG +  IV  DA +    ++++      +G+ C    R+ V E +YD  + +  AA + +++GDP DE+   G   ++  +      +D  K+ G  +  GGE +G++G F++PT+  ++  D  IV  E F P++ V K K+ D+ I + N+ E GL++ + T ++++  +    +  + G V +N   N       FGG   +G GRE   D+ + Y++
Sbjct:   62 FEVINPSTEEEICHIYEGREDDVEEAVQAADRAFSNGSWNGIDPIDRGKALYRLAELIEQDKDVIASIETLDNGKAISSSRGDVDLVINYLKSSAGFADKIDGRMIDTGR-THFSYTKRQPLGVCGQIIPWNFPLLMWAWKIAPALVTGNTVVLKTAESTPLSALYVSKYI----PQAGIPPGVINIVSGFGKIVGEAITNHPKIKKVAFTGSTATGRHIYQSAAAGLKKVTLELGGKSPNIVFADAELKKAVQNIILGIYYNSGEVCCAGSRVYVEESIYDKFIEEFKAASESIKVGDPFDESTFQGAQTSQMQLNKILKYVDIGKNEGATLITGGERLGSKGYFIKPTVFGDVKEDMRIVKEEIFGPVVTVTKFKSADEVINMANDSEYGLAAGIHTSNINTALKV--ADRVNAGTVWINT-YNDFHHAVPFGGFNASGLGREMSVDALQNYLQ 509          

Query:  253 TASGTEFEQLCPSNNKIIAKIKMSSLEDCNRCI-AETYKTNKVWRNLPAPYRGEIVRQIGYRFRQKKDIIAKLLSLEVGKIY-AEGKGEVQEIIDICDFATGLSRMFN-GSIFPSERQNHLLLEQWNPLGVVGVISAFNFPAAVFGWNLALALVCGNSVVWKGAPSTNLTTIAVSNIIIEVLKENNLPTSIVTALCG-GTDVGQALVADKRIALVSFTGSCSAGAKVQQAV-TNRFGRCLLELGGNNAIIVNHDANIDMVTRSVLFAAAG---TAGQRCTTTRRLLVHEDVYDLVLSKLIAAYKK----LRIGDPMDENVTIGPLHTKGAVEMFKNCIDQVKSSXXXXXXXXXXXX---XXXNFVQPTIVTNLAHDHPIVHNETFVPIIYVIKIKNLDQAITINNEVEQGLSSSLFTRDLSSIYRWLGPEGSDCGLVNVNIPTNGAEIGGAFGGEKMTGGGRESGSDSWKQYMRRSTCTINCGTD 1662
            ++ G   E + P+  + I   + ++ +D ++ + A     + VW    +  RG  +  +     +++D +A L +L+ GK Y +  KG++ +I+ +  +  G +  F+ G+  P    N        P GVV  I  +N+P A+  W L  AL  GN+V+ K A +T+L+ +  + +I    K+   P  +V  + G G+ VGQAL +   I  +SFTGS   G  V +A   +      LE GG +  +V  DA++D   +++ + AAG    +GQ CT   R+ V   +YD  + K     KK        DP DE   +GP+ +    +  K+ I++ K       F          +G F+ PTI T++     ++ +E F P++ V K  N D A+ + N+   GL+S++FT+D+   + +        G V +N  +N  ++   FGG KM+G GRE G      Y++     IN   D
Sbjct:   32 SSDGKTIETVNPATGEPITSFQAANEKDVDKAVKAARAAFDNVWSKTSSEQRGIYLSNLLKLIEEEQDTLAALETLDAGKPYHSNAKGDLAQILQLTRYFAGSADKFDKGATIPLTF-NKFAYTLKVPFGVVAQIVPWNYPLAMACWKLQGALAAGNTVIIKPAENTSLSLLYFATLI----KKAGFPPGVVNIVPGYGSLVGQALASHMDIDKISFTGSTKVGGFVLEASGQSNLKDVTLECGGKSPALVFEDADLD---KAIDWIAAGIFYNSGQNCTANSRVYVQSSIYDKFVEKFKETAKKEWDVAGKFDPFDEKCIVGPVISSTQYDRIKSYIERGKREEKLDMFQTSEFPIGGAKGYFIPPTIFTDVPQTSKLLQDEIFGPVVVVSKFTNYDDALKLANDTCYGLASAVFTKDVKKAHMFA--RDIKAGTVWIN-SSNDEDVTVPFGGFKMSGIGRELGQSGVDTYLQTKAVHINLSLD 505          

Query:  271 FEQLCPSNNKIIAKIKMSSLEDCNRCIAETYKTNKV-WRNLPAPYRGEIVRQIGYRFRQKKDIIAKLLSLEVGKIYAEGKGEVQEIIDICDFATGLSRMFNGSIFPSERQNHLLLEQWNPLGVVGVISAFNFPAAVFGWNLALALVCGNSVVWKGAPSTNLTTIAVSNIIIEVLKENNLPTSIVTALCG-GTDVGQALVADKRIALVSFTGSCSAGAKVQQAVTNRFGRCLLELGGNNAIIVNHDANIDMVTRSVLFAAAGTAGQRCTTTRRLLVHEDVYDLVLSKLIAAYKKLRIGDPMDENVTIGPLHTKGAVEMFKNCIDQVKSSXXXXXXXXXXXXXXXNFVQPTIVTNLAHDHPIVHNETFVPIIYVIKIKNLDQAITINNEVEQGLSSSLFTRDLSSIYRWLGPEGSDCGLVNVNIPTNGAEIGGAFGGEKMTGGGRESGSDSWKQYMRRSTCTINCGTDLPL 1671
            F+ + PSN + I  +  +  +D +  +A   K  +  W  +    R + +  +     + ++ +A + S++ GK     +G+V  +        G +    G++  + + NH       PLGV G I  +NFP  ++ W +  AL  GN+VV K A +T L+ +  S    ++ +E  +P  +V  L G G  VG+ L A   +  ++FTGS + G  + +   +   +  LELGG +  IV  DA++D   +++ F     +G+ C    R+ + + VY+ VL KL    + L++GDP DE V  G   +   +    + +D  KS G ++  GG   G++G FV+PT+  ++  D  IV  E F PI+ V K   +D+ I + N+ + GL++ + T D++        +    G V +N   N  +    FGG   +G GRE G  +   Y +  T ++    D P+
Sbjct:   61 FDVINPSNEEKITTVYKAMEDDVDEAVAAAKKAFETKWSIVEPEVRAKALFNLADLVEKHQETLAAIESMDNGKSLFCARGDVALVSKYLRSCGGWADKIYGNVIDTGK-NHFTYSIKEPLGVCGQIIPWNFPLLMWSWKIGPALATGNTVVLKPAETTPLSALFAS----QLCQEAGIPAGVVNILPGSGRVVGERLSAHPDVKKIAFTGSTATGRHIMKVAADTVKKVTLELGGKSPNIVFADADLDKAVKNIAFGIFYNSGEVCCAGSRIYIQDTVYEEVLQKLKDYTESLKVGDPFDEEVFQGAQTSDKQLHKILDYVDVAKSEGARLVTGGARHGSKGYFVKPTVFADVKEDMRIVKEEVFGPIVTVSKFSTVDEVIAMANDSQYGLAAGIHTNDINKAVDV--SKRVKAGTVWINTYNNFHQ-NVPFGGFGQSGIGREMGEAALSNYTQ--TKSVRIAIDKPI 519          

Query:  253 TASGTEFEQLCPSNNKIIAKIKMSSLEDCNRCI-AETYKTNKVWRNLPAPYRGEIVRQIGYRFRQKKDIIAKLLSLEVGK-IYAEGKGEVQEIIDICDFATGLSRMFN-GSIFPSERQNHLLLEQWNPLGVVGVISAFNFPAAVFGWNLALALVCGNSVVWKGAPSTNLTTIAVSNIIIEVLKENNLPTSIVTALCG-GTDVGQALVADKRIALVSFTGSCSAGAKVQQAV-TNRFGRCLLELGGNNAIIVNHDANIDMVTRSVLFAAAGTAGQRCTTTRRLLVHEDVYDLVLSKLIAAYKK----LRIGDPMDENVTIGPLHTKGAVEMFKNCIDQVKSSXXXXXXXXXXXX---XXXNFVQPTIVTNLAHDHPIVHNETFVPIIYVIKIKNLDQAITINNEVEQGLSSSLFTRDLSSIYRWLGPEGSDCGLVNVNIPTNGAEIGGAFGGEKMTGGGRESGSDSWKQYMRRSTCTINCGTD 1662
            ++ G   E + P+  + I   + ++ +D ++ + A     + VW    +  RG  +  +     +++D +A L +L+ GK  ++  K ++ +II++  +  G    FN G   P    N        P GVV  I  +N+P A+    +  AL  GN+V+ K A +T+L+ +  + +I    K+   P  +V  + G G+ VG+AL     I  +SFTGS   G  V +A   +      LE GG +  +V  DA++D     V       +GQ CT   R+ V   +YD  + K     KK        DP DE   +GP+ +    +  K+ I++ K       F          +G F+ PTI T++     ++ +E F P++ V K  N D A+ + N+   GL+S++FT+D+   + +        G V +N  TN  E    FGG KM+G GRESG      Y++  +  ++   D
Sbjct:   32 SSDGKTIETVNPATGEPITSFQAANEKDVDKAVKAARAAFDNVWSKTSSEQRGIYLSNLLKLIEEEQDTLAALETLDAGKPFHSNAKQDLAQIIELTRYYAGAVDKFNMGETIPLTF-NKFAYTLKVPFGVVAQIVPWNYPLAMACRKMQGALAAGNTVIIKPAENTSLSLLYFATLI----KKAGFPPGVVNVIPGYGSVVGKALGTHMDIDKISFTGSTKVGGSVLEASGQSNLKDITLECGGKSPALVFEDADLDKAIEWVANGIFFNSGQICTANSRVYVQSSIYDKFVEKFKETAKKEWDVAGKFDPFDEKCIVGPVISSTQYDRIKSYIERGKKEEKLDMFQTSEFPIGGAKGYFIPPTIFTDVPETSKLLRDEIFGPVVVVSKFTNYDDALKLANDTCYGLASAVFTKDVKKAHMFA--RDIKAGTVWIN-QTNQEEAKVPFGGFKMSGIGRESGDTGVDNYLQIKSVHVDLSLD 505          

Query:  286 PSNNKIIAKIKMSSLEDCNRCI--AETYKTNKVWRNLPAPYRGEIVRQIGYRFRQKKDIIAKLLSLEVGKIYAEGKGEVQEIIDICDFATGLSRMFNGSIFPSERQNHLLLEQWNPLGVVGVISAFNFPAAVFGWNLALALVCGNSVVWKGAPSTNLTTIAVSNIIIEVLKENNLPTSIVTALCG-GTDVGQALVADKRIALVSFTGSCSAGAKVQ-QAVTNRFGRCLLELGGNNAIIVNHDANIDMVTRSVLFAAAGTAGQRCTTTRRLLVHEDVYDLVLSKLIAAYK-----KLRIGDPMDENVTIGPLHTKGAVEMFKNCIDQVKSSXXXXXXXXXXXXXXXNFVQPTIVTNLAHDHPIVHNETFVPIIYVIKIKNLDQAITINNEVEQGLSSSLFTRDLSS---IYRWLGPEGSDCGLVNVNIPTNGAEIGGAFGGEKMTGGGRESGSDSWKQY 1623
            PS    + ++  ++ ED    I  A+    +  W       RG ++ ++      + D+++ + +L+ GK  A  +G+V   I+    A   +   NG    +    ++      P+GV G I  +NFP  +  W +A AL  GN  + K A  T L  +  +++     K+  +P  +V  + G G  VG AL  D RI  ++FTGS   G  V   +  +   +  LELGG +A +V  DANI     +++      AGQ C++  R+ V E +YD    +L+AA+K     ++++G+P D+    G +  +   +   N ID  K  G KI  GGE +G +G F++PT+  ++  D  IV  E F P++ V K K L++ + + N  E GL S + T  LS+   + + L       G V +N   N  +    FGG K +G GRE G + +  Y
Sbjct:   48 PSTENTVCEVSSATTEDVEYAIECADRAFHDTEWATQDPRERGRLLSKLADELESQIDLVSSIEALDNGKTLALARGDVTIAINCLRDAAAYADKVNGRTI-NTGDGYMNFTTLEPIGVCGQIIPWNFPIMMLAWKIAPALAMGNVCILKPAAVTPLNALYFASL----CKKVGIPAGVVNIVPGPGRTVGAALTNDPRIRKLAFTGSTEVGKSVAVDSSESNLKKITLELGGKSAHLVFDDANIKKTLPNLVNGIFKNAGQICSSGSRIYVQEGIYD----ELLAAFKAYLETEIKVGNPFDKANFQGAITNRQQFDTIMNYIDIGKKEGAKILTGGEKVGDKGYFIRPTVFYDVNEDMRIVKEEIFGPVVTVAKFKTLEEGVEMANSSEFGLGSGIETESLSTGLKVAKML-----KAGTVWINT-YNDFDSRVPFGGVKQSGYGREMGEEVYHAY 490          

Query:  115 LFNLSKSFFRSNQRFSCYMIQSPEYSWLKDLGLKDYNNGVYDGNNWTASGTEFEQLCPSNNKIIAKIKMSSLEDCNRCIAETYKTNKVWRNLPAPYRGEIVRQIGYRFRQKKDIIAKLLSLEVGKIYAEGKGEVQEIIDICDFATGLSRMFNGSIFPSERQNHLLLEQWNPLGVVGVISAFNFPAAVFGWNLALALVCGNSVVWKGAPSTNLTTIAVSNIIIEVLKENNLPTSIVTALCGGTDVGQALVADKRIALVSFTGSCSAGAKVQQAVTNRFGRCLLELGGNNAIIVNHDANIDMV-TRSVLFAAA--GTAGQRCTTTRRLLVHEDVYDLVLSKLIAAYKKLRIGDPMDENVTIGPLHTKGAVEMFKNCIDQVKSSXXXXXXXXXXXXXXXNFVQPTIVTNLAHDHPIVHNETFVPIIYVIKIKNLDQAITINNEVEQGLSSSLFTRDLSSIYRWLGPEGSDCGLVNVNIPTNGAEIGGAFGGEKMTGGGRESGSDSWKQYMRRSTCTINCGTDLPLAQGIVF 1689
            LF  S++ F ++Q     +I++ +YSWL++LGLK  N GVY+G  W   G     +CPSN + IA+++  S+ED +  +    +  K W   P P RGE+VRQIG+  R+K   + KLLSLEVGKI+ EG GE+QE ID+CD+A GLSRMF+G +FPSER  H LLEQWNP+G VGVI+AFNFP AVFGWN A+++ CGN  +WKGAPST LT++AV+ I+  VL+ N    ++ + +CGG ++G+A+  D RI LVSFTGS + G KV  AV  RFGR LLELGGNNAIIV       +V T+ + ++    GTAGQRCTTTRRL++HE ++D V+ KL  AY ++++GDP+D+ V  GPLH + AV ++ N I+  KS GG +E GG+ +   G +V+PTIVT L HD  IVH E+FVPI+YV+K KN ++A++ NNEV        +  D+  +++W+GP GSDCG+VNVNIPT+GAEIGGAFGGEK TGGGRESGSDSWK YMRRSTCTIN   DLPLAQGI F
Sbjct:   20 LFLNSRNCFSTSQS-GALLIENEKYSWLRELGLKADNPGVYNGT-WGGKGEVVTSICPSNGQPIARVQQGSVEDYDATVKLAKEAWKSWAMTPGPKRGEVVRQIGHALREKLTPLGKLLSLEVGKIFPEGVGEIQEYIDVCDYAVGLSRMFDGKVFPSERPGHALLEQWNPVGTVGVITAFNFPVAVFGWNTAISMTCGNVNIWKGAPSTPLTSVAVTRIVGSVLEANGFSGAVSSLVCGGAEIGEAIAKDPRIDLVSFTGSTAVGQKVGVAVQERFGRKLLELGGNNAIIVLECFKYCIVLTQGICYSVGIVGTAGQRCTTTRRLILHESIHDQVVEKLKKAYAQVKMGDPLDDGVIYGPLHNEQAVAIYLNAIEAAKSQGGTVECGGKVVDRPGYYVEPTIVTGLKHDAEIVHTESFVPILYVLKCKNFEEAVSFNNEVSNVCPEISYRADMGKLFQWMGPMGSDCGIVNVNIPTSGAEIGGAFGGEKHTGGGRESGSDSWKAYMRRSTCTINYSKDLPLAQGIKF 545          

Query: 1006 IDMVTRSVLFAAAGTAGQRCTTTRRLLVHEDVYDLVLSKLIAAYKKLRIGDPMDENVTIGPLHTKGAVEMFKNCIDQVKSSXXXXXXXXXXXXXXXNFVQPTIVTNLAHDHPIVHNETFVPIIYVIKIKNLDQAITINNEVEQGLSSSLFTR-DLSSIYRWLGPEGSDCGLVNVNIPTNGAEIGGAFG 1566
            +D+V  SVLFA+ GTAGQRCTTTRRL++HE ++D V+ KL  AY ++++GDP+D+ V  GPLH + AV ++ N I+  KS GG +E GG+ +   G +V+PTIVT L HD  IVH E+FVPI+YV+K K   Q    N + E G+ +    R D+  +++W+GP GSDCG+VNVNIPT+GAEIGGAFG
Sbjct:    1 MDLVVPSVLFASVGTAGQRCTTTRRLILHESIHDQVVEKLKKAYAQVKMGDPLDDGVIYGPLHNEQAVAIYLNAIEAAKSQGGTVECGGKVVDRPGYYVEPTIVTGLKHDAEIVHTESFVPILYVLKCKLAWQCYDYNCKFEPGVMARDTNRADMGKLFQWMGPMGSDCGIVNVNIPTSGAEIGGAFG 188          

Query:  286 PSNNKIIAKIKMSSLEDCNRCIAETYKTNKVWRNLPAPYRGEIVRQIGYRFRQKKDIIAKLLSLEVGKIYAEGKGEVQEIIDICDFATGLS--------RMFNGSIFPSERQNHLLLEQWNPLGVVGVISAFNFPAAVFGWNLALALVCGNSVVWKGAPSTNLTTIAVSNIIIEVLKENNLPTSIVTALCGGTDVGQALVADKRIALVSFTGSCSAGAKVQQAVTNRFGRCLLELGGNNAIIVNHDANIDMVTRSVLFAAAGTAGQRCTTTRRLLVHEDVYDLVLSKLIAAYKKLRIGDPMDENVTIGPL----HTKGAVEMFKNCIDQ-VKSSXXXXXXXXXXXXXXXNFVQPTIVTNLAHDHPIVHNETFVPIIYVIKIKNLDQAITINNEVEQGLSSSLFTRDLSSIYRWLGP-EGSDCGLVNVNIPTNGAEIGGAFGGEKMTGGGRESGSDSWKQYMRRSTCTINCG 1656
            PS   I  ++K S   +  R +    K  K W  L    RG I+       R++++ IAK+   + GK + E   +V  + D+ ++  G++        ++ NGS   + R+         PLGVVG I A+N+P     W +A A+ CGN++V+K +P T +  +A+++I    L E  +P  +V  + GG + G+ L  D  +A VSFTGS   G K+  +  +      LELGG + +I+  DA++       L A   + GQ C+   R+ V + + D  L K++   K +R+GDPM  +  +G +    H    ++  +   D+  K   G          T G ++ P ++     D  +V  E F P++ V+  +  ++A+T  N    GL+  +FTRDL+  +R +G  +   C + + NI      +   FGG KM+G GRE G+ + + Y +  T  +  G
Sbjct:    6 PSTGHISCEVKGSGKTEVKRAVLSARKAFKTWSVLSGSERGRILGDASRLVRKRREDIAKVEVHDNGKPFHEALWDVDNVADVLEYYAGVAPTLSGQHVQLPNGSFAYTRRE---------PLGVVGGIGAWNYPIQTACWKIAPAIACGNTIVYKPSPLTPMNAVALADI----LTEAGVPPGVVNIIQGGGETGEMLSKDPNVAKVSFTGSVPTGQKIMASCADGIKHVTLELGGKSPLIIFKDADMANAVSGALMANFLSQGQVCSNGTRVFVEDSIKDEFLEKVVERTKNIRVGDPMAPDTQMGAMISSAHLNKVLDYVQIGKDEGAKVLCGGERLHLPEPLTSGYYMSPCVMAECTDDMTVVKEEIFGPVMTVLTFQTEEEAVTRANNTTFGLAGGIFTRDLNRAHRVIGSLQAGTCWINSFNI----TPVEVPFGGYKMSGFGREGGTAAVEHYTQLKTVYVEMG 459          

Query:  259 SGTEFEQLCPSNNKIIAKIKMSSLEDCNRCIA---ETYKTNKVWRNLPAPYRGEIVRQIGYRFRQKKDIIAKLLSLEVGKIYAEGKGEVQEIIDICDFATGLSRMFNGSIFPSERQNHLLLEQWNPLGVVGVISAFNFPAAVFGWNLALALVCGNSVVWKGAPSTNLTTIAVSNIIIEVLKENNLPTSIVTALCG-GTDVGQALVADKRIALVSFTGSCSAGAKVQQA-VTNRFGRCLLELGGNNAIIVNHDANIDMVTRSVLFAAAGTAGQRCTTTRRLLVHEDVYDLVLSKLIAAYKKLRIGDPMDENVTIGPLHTKGAVEMFKNCIDQVKSSXXXXXXXXXXXXXXXN---FVQPTIVTNLAHDHPIVHNETFVPIIYVIKIKNLDQAITINNEVEQGLSSSLFTRDLSSIYRWLGPEGSDCGLVNVNIPTNGAEIGGAFGGEKMTGGGRESGSDSWKQYMRRSTCTINCGT-DLPL 1671
            SG  F  + P+  + I  I     ED ++ +    E +K    WR + A  RG+++ ++     +    +A L +++ GK++++  G++Q   +   +  G +    G   P++   + +  +  P+G+VG I+ +NFP  +    +A AL CGN V+ K A  T LT +    ++    KE   P  +V  + G G   G A+     I  VSFTGS   G  +Q+A   +   R  LELGG +  IV  D+++D        A     GQ C+   R  V + +YD  + K +   K   +GDP D +V  GP   +   E F   +D ++S   +           GN   F+QPT+ +++  D  I   E F P+  +IK K++D+ I   N    GL++ +FT+++ +        G   G V +N    GA     FGG KM+G GRE     W +Y     C +   T  +PL
Sbjct:   29 SGKVFPTINPTTGEKICDISEGDKEDVDKAVKAAKEAFKLGSAWRTMDASMRGKLLYKLAQLIDRDIAYLASLETIDSGKLFSDSVGDMQSSANCFRYYAGWADKVTGKTIPADGP-YFVYTRHEPVGLVGAITPWNFPLNMASVKIAPALACGNVVILKPAEQTPLTALYFCALV----KEAGFPAGVVNVIPGYGPTAGAAITTHLDIDKVSFTGSTEVGRLIQEASAKSNLKRLTLELGGKSPNIVFADSDMDYAVEMAHEALFFNQGQCCSAGSRTFVQDTIYDEFVKKSVKRAKARTVGDPFD-SVEQGPQIDQ---EQFDKIMDLIESGKKEGAKMQCGGARHGNKGFFIQPTVFSDVTDDMRIAKEEIFGPVQQLIKFKSVDEVIERANNTTYGLAAGVFTKNIDTAIAV--SSGLRAGTVWINCYECGAP-QAPFGGYKMSGYGRE-----WGEYGVLPYCEVKTVTMKVPL 491          

Query:  262 GTEFEQLCPSNNKIIAKIKMSSLEDCNRCI--AETYKTNKVWRNLPAPYRGEIVRQIGYRFRQKKDIIAKLLSLEVGKIYAEG-KGEVQEIIDICDFATGLSRMFNGSIFP---SERQNHLLLEQWNPLGVVGVISAFNFPAAVFGWNLALALVCGNSVVWKGAPSTNLTTIAVSNIIIEVLKENNLPTSIVTALCG-GTDVGQALVADKRIALVSFTGSCSAGAKVQQA-VTNRFGRCLLELGGNNAIIVNHDANIDMVTRSVLFAAAGTAGQRCTTTRRLLVHEDVYDLVLSKLIAAYKKLRIGDPMDENVTIGPLHTKGAVEMFKNCIDQVKSSXXXXXXXXXXXXXXXNFVQPTIVTNLAHDHPIVHNETFVPIIYVIKIKNLD--QAITINNEVEQGLSSSLFTRDLSSIYRWLGPEGSDCGLVNVNIPTNGAEIGGAFGGEKMTGGGRESGSDSWKQYMRRSTCTI 1647
            G  F  + P++  ++A++ +++ ED +  +  A+    N  W ++ A  R  ++ ++     Q K+ +A + SL+ G +Y    K  V   ID   +  G      G   P   ++   +L   +  P+GV G+I  +N+P  +  W ++  L  GN+VV K A  T +T +  +    E+      P  ++  L G G+ VG  +     +  + FTGS   G  + ++  T+   +C LELGG + +I+  D +++   R  + A     G+ C    RL V E ++D  +++L+   KKL+IGDP+D     GP + K  ++     + +    G K+ +GG  +   G F +P + TN+  D  I   E+F P++ + K  + D    +   N  E GL+S +FT+D+S   R    +  + G   VN   N  ++   FGG K +G G++ G ++  +Y++    TI
Sbjct:  408 GKTFNTINPTDGTVLAQVSLATHEDVDDAVDAAKEAFYNGPWGSMNARDRATLMNRLADLMEQHKEELATIESLDSGAVYTLALKTHVGMSIDTVRYFAGWCDKIQGLTVPVNNAKPNRNLCYTKREPIGVCGLIVPWNYPLMMLAWKISPLLAAGNTVVLKPAQVTPMTALKFA----ELAARAGFPKGVINILPGSGSVVGNRICEHPDVRKLGFTGSTPVGKAIMESCATSNLKKCSLELGGKSPLIIFSDCDMERAVRQGMMACLFNKGENCIAAGRLFVEESIHDEFVNRLVDELKKLKIGDPLDTATDHGPQNHKAHLDSLVEYVKRGVEEGAKLVYGGRHLDRPGFFFEPAVFTNVEDDMFIAKEESFGPVVIISKFDDGDVEGVLESANGTEYGLASGVFTKDMSKALRVA--DALEAGTCFVNT-YNKTDVAAPFGGCKQSGFGKDLGMEALNEYLKTKVITI 872          

Query:  112 FLFNLSKSFFRSNQR--FSCYMIQSPEYSWLKDLGLKDYNNGVYDGNNWTASGTEFEQLCPSNNKIIAKIKMSSLEDCNRCIAETYKTNKVWRNLPAPYRGEIVRQIGYRFRQKKDIIAKLLSLEVGKIYAEGKGEVQEIIDICDFATGLSRMFNGSIFPSERQNHLLLEQWNPLGVVGVISAFNFPAAVFGWNLALALVCGNSVVWKGAPSTNLTTIAVSNIIIEVLKENNLPTSIVTALCGGTDVGQALVADKRIALVSFTGSCSAGAKVQQAVTNRFGRCLLELGGNNAIIVNHDANIDMVTRSVLFAAAGTAGQRCTTTRRLLVHEDVYDLVLSKLIAAYKKLRIGDPMDENVTIGPLHTKGAVEMFKNCIDQVKSSXXXXXXXXXXXXXXXNFVQPTIVTNLAHDHPIVHNETFVPIIYVIKIKNLDQAITINNEVEQGLSSSLFTRDLSSIYRWLGPEGSDCGLVNVNIPTNGAEIGGAFGGEKMTGGGRESGSDSWKQYMRRSTCTINCGTDLPLAQGIVFE 1692
             L     S F   Q    S  +I  P+YSWLK+LGL + N GVY+G+ W  SG      CP+NN+ IA++  ++L +    + +  +  K+W ++PAP RGE+VRQIG   R+K  ++  L+SLE+GKIY EG GEVQE +D+CD+A GLSRM  G + PSER  H+L+EQWNP+G+VG+I+AFNFP AV+GWN A+AL+CGN  +WKGAP+T LT++AV+ I+ EVL++NNLP +I +  CGG DVG A+  D+R+ L+SFTGS   G  V   V  RFGR LLELGGNNAII   DA++++V  S +FA+ GTAGQRCTTTRRL++HE ++D V+ ++  AYK++RIGDP D N   GPLHTK AVE +   ++Q K  GG I  GG+ +   GN+V+PTI+T L H+ PIVH ETFVPI+YV+K K  ++A   NNEV+QGLSSS+FT+D+  ++RWLGP+GSDCG+VNVNIPT+GAEIGGAFGGEK TGGGRESGSDSWKQYMRRSTCTIN   DLPLAQGI FE
Sbjct:   19 LLLQKRISSFHCQQSATMSSLLINQPKYSWLKELGLSEDNPGVYNGS-WGGSGEVITSYCPANNEPIARVTQATLAEYEETVQKAKEAWKLWADIPAPKRGEVVRQIGDALRKKIKVLGSLVSLEMGKIYVEGVGEVQEYVDVCDYAVGLSRMIGGPMLPSERPGHVLIEQWNPVGLVGIITAFNFPVAVYGWNNAIALICGNVCLWKGAPTTPLTSVAVTKIVAEVLEQNNLPGAICSMTCGGADVGTAMAKDERVDLLSFTGSTHVGKMVAMTVQERFGRKLLELGGNNAIIAFEDADLNLVVPSAVFASVGTAGQRCTTTRRLMLHESLHDTVVERIAKAYKQVRIGDPWDPNTLYGPLHTKQAVEQYLAAVEQAKQQGGTIVCGGKVMDRPGNYVEPTIITGLPHNAPIVHTETFVPILYVLKFKTEEEAFAWNNEVQQGLSSSIFTKDMGRVFRWLGPKGSDCGIVNVNIPTSGAEIGGAFGGEKHTGGGRESGSDSWKQYMRRSTCTINYSKDLPLAQGIKFE 546          

Query:  112 FLFNLSKSFFRSNQR--FSCYMIQSPEYSWLKDLGLKDYNNGVYDGNNWTASGTEFEQLCPSNNKIIAKIKMSSLEDCNRCIAETYKTNKVWRNLPAPYRGEIVRQIGYRFRQKKDIIAKLLSLEVGKIYAEGKGEVQEIIDICDFATGLSRMFNGSIFPSERQNHLLLEQWNPLGVVGVISAFNFPAAVFGWNLALALVCGNSVVWKGAPSTNLTTIAVSNIIIEVLKENNLPTSIVTALCGGTDVGQALVADKRIALVSFTGSCSAGAKVQQAVTNRFGRCLLELGGNNAIIVNHDANIDMVTRSVLFAAAGTAGQRCTTTRRLLVHEDVYDLVLSKLIAAYKKLRIGDPMDENVTIGPLHTKGAVEMFKNCIDQVKSSXXXXXXXXXXXXXXXNFVQPTIVTNLAHDHPIVHNETFVPIIYVIKIKNLDQAITINNEVEQGLSSSLFTRDLSSIYRWLGPEGSDCGLVNVNIPTNGAEIGGAFGGEKMTGGGRESGSDSWKQYMRRSTCTINCGTDLPLAQGIVFE 1692
             L     S F   Q    S  +I  P+YSWLK+LGL + N GVY+G+ W  SG      CP+NN+ IA++  ++L +    + +  +  K+W ++PAP RGE+VRQIG   R+K  ++  L+SLE+GKIY EG GEVQE +D+CD+A GLSRM  G + PSER  H+L+EQWNP+G+VG+I+AFNFP AV+GWN A+AL+CGN  +WKGAP+T LT++AV+ I+ EVL++NNLP +I +  CGG DVG A+  D+R                           LLEL                   S +FA+ GTAGQR                            RIGDP D N   GPLHTK AVE +   ++Q K  GG I  GG+ +   GN+V+PTI+T L H+ PIVH ETFVPI+YV+K K  ++A   NNEV+QGLSSS+FT+D+  ++RWLGP+GSDCG+VNVNIPT+GAEIGGAFGGEK TGGGRESGSDSWKQYMRRSTCTIN   DLPLAQGI FE
Sbjct:    6 LLLQKRISSFHCQQSATMSSLLINQPKYSWLKELGLSEDNPGVYNGS-WGGSGEVITSYCPANNEPIARVTQATLAEYEETVQKAKEAWKLWADIPAPKRGEVVRQIGDALRKKIKVLGSLVSLEMGKIYVEGVGEVQEYVDVCDYAVGLSRMIGGPMLPSERPGHVLIEQWNPVGLVGIITAFNFPVAVYGWNNAIALICGNVCLWKGAPTTPLTSVAVTKIVAEVLEQNNLPGAICSMTCGGADVGTAMAKDER---------------------------LLEL-----------------VPSAVFASVGTAGQR---------------------------FRIGDPWDPNTLYGPLHTKQAVEQYLAAVEQAKQQGGTIVCGGKVMDRPGNYVEPTIITGLPHNAPIVHTETFVPILYVLKFKTEEEAFAWNNEVQQGLSSSIFTKDMGRVFRWLGPKGSDCGIVNVNIPTSGAEIGGAFGGEKHTGGGRESGSDSWKQYMRRSTCTINYSKDLPLAQGIKFE 462          

Query:  286 PSNNKIIAKIKMSSLEDCNRCIAETYKTNKVWRNLPAPYRGEIVRQIGYRFRQKKDIIAKLLSLEVGKIYAEGKGEVQEIIDICDFATGLSRMFNGSIFPSERQNHLLLEQWNPLGVVGVISAFNFPAAVFGWNLALALVCGNSVVWKGAPSTNLTTIAVSNIIIEVLKENNLPTSIVTALCGGTDVGQALVADKRIALVSFTGSCSAGAKVQQAVTNRFGRCLLELGGNNAIIVNHDANIDMVTRSVLFAAAGTAGQRCTTTRRLLVHEDVYDLVLSKLIAAYKKLRIGDPMDENVTIGPLHTKGAVEMFKNCIDQVKSSXXXXX------XXXXXXXXXXNFVQPTIVTNLAHDHPIVHNETFVPIIYVIKIKNLDQAITINNEVEQGLSSSLFTRDLSSIYRWLGP-EGSDCGLVNVNIPTNGAEIGGAFGGEKMTGGGRESGSDSWKQYMRRSTCTINCG 1656
            P+  +++ ++     E+ +  I   +     W       R  ++ +     R++++ IAKL  +  GK   E   ++       ++  GL+    G  F           +  PLGV   I A+N+P  +  W  A AL CGN++V+K +P T +T +    I+ E+ KE  +P  +   + GG + G  L    ++A VSFTGS   G KV +       +  LELGG + +I+  D +++   +  L A   T GQ C    R+ VH+D+    L +++   K + +GDP+ ++  +G L TK  +E     + Q K  GG++          +     G F+ P I+ N   D   V  E F P++ V+     ++ I   N    GL+S +FTRD+S  +R     E   C + N NI    + +   FGG KM+G GRE+G  + + Y +  T  +  G
Sbjct:   45 PATGRVLCQMVPCGAEEVDEAIMSAHAAYVQWSKKAGTERARVMLEAARIIRERREKIAKLEVINNGKSITEALVDIDVSWQCIEYYAGLAGTLAGQHF-QLPGGAFAYTRREPLGVCVGIGAWNYPFQIAAWKSAPALACGNAMVFKPSPFTPVTAV----ILAEIYKEAGVPDGLFCVVQGGAETGSLLCNHPKVAKVSFTGSVPTGKKVMEMSAKGVKQVTLELGGKSPLIIFKDCDLENAVKGALMANFLTQGQVCCNGTRVFVHKDILPQFLEEVVKRTKAIAVGDPLLDSTRMGALITKPHLEKVLGFVSQAKKEGGRVLCGGEPFVPSDPKLKGGYFMSPCILDNCRDDMTCVKEEIFGPVMSVLPFDTEEEVIRRANNTTFGLASGVFTRDISRAHRVAASLEAGTCFINNYNI----SPVEVPFGGYKMSGFGRENGQVTIEYYSQLKTVVVETG 499          

Query:  286 PSNNKIIAKIKMSSLEDCNRCIAETYKTNKVWRNLPAPYRGEIVRQIGYRFRQKKDIIAKLLSLEVGKIYAEGKGEVQEIIDICDFATGLSRMFNGSIFPSERQNHLLLEQWNPLGVVGVISAFNFPAAVFGWNLALALVCGNSVVWKGAPSTNLTTIAVSNIIIEVLKENNLPTSIVTALCGGTDVGQALVADKRIALVSFTGSCSAGAKVQQAVTNRFGRCLLELGGNNAIIVNHDANIDMVTRSVLFAAAGTAGQRCTTTRRLLVHEDVYDLVLSKLIAAYKKLRIGDPMDENVTIGPLHTKGAVEMFKNCIDQVKSSXXXXX------XXXXXXXXXXNFVQPTIVTNLAHDHPIVHNETFVPIIYVIKIKNLDQAITINNEVEQGLSSSLFTRDLSSIYRWLGP-EGSDCGLVNVNIPTNGAEIGGAFGGEKMTGGGRESGSDSWKQYMRRSTCTINCG 1656
            P+  +++ ++     E+ +  I   +     W       R  ++ +     R++++ IAKL  +  GK   E   ++       ++  GL+    G  F           +  PLGV   I A+N+P  +  W  A AL CGN++V+K +P T +T +    I+ E+ KE  +P  +   + GG + G  L    ++A VSFTGS   G KV +       +  LELGG + +I+  D +++   +  L A   T GQ C    R+ VH+D+    L +++   K + +GDP+ ++  +G L TK  +E     + Q K  GG++          +     G F+ P I+ N   D   V  E F P++ V+     ++ I   N    GL+S +FTRD+S  +R     E   C + N NI    + +   FGG KM+G GRE+G  + + Y +  T  +  G
Sbjct:   45 PATGRVLCQMVPCGAEEVDEAIMSAHAAYVQWSKKAGTERARVMLEAARIIRERREKIAKLEVINNGKSITEALVDIDVSWQCIEYYAGLAGTLAGQHF-QLPGGAFAYTRREPLGVCVGIGAWNYPFQIAAWKSAPALACGNAMVFKPSPFTPVTAV----ILAEIYKEAGVPDGLFCVVQGGAETGSLLCNHPKVAKVSFTGSVPTGKKVMEMSAKGVKQVTLELGGKSPLIIFKDCDLENAVKGALMANFLTQGQVCCNGTRVFVHKDILPQFLEEVVKRTKAIAVGDPLLDSTRMGALITKPHLEKVLGFVSQAKKEGGRVLCGGEPFVPSDPKLKGGYFMSPCILDNCRDDMTCVKEEIFGPVMSVLPFDTEEEVIRRANNTTFGLASGVFTRDISRAHRVAASLEAGTCFINNYNI----SPVEVPFGGYKMSGFGRENGQVTIEYYSQLKTVVVETG 499          

Query:  232 VYDGNNW--TASGTEFEQLCPSNNKIIAKIKMSSLEDCNRCIAET---YKTNKVWRNLPAPYRGEIVRQIGYRFRQKKDIIAKLLSLEVGKIYAEGKG-EVQEIIDICDFATGLSRMFNGSIFPSERQNHLLLEQWNPLGVVGVISAFNFPAAVFGWNLALALVCGNSVVWKGAPSTNLTTIAVSNIIIEVLKENNLPTSIVTALCG-GTDVGQALVADKRIALVSFTGSCSAGAKVQQAV-TNRFGRCLLELGGNNAIIVNHDANIDMVTRSVLFAAAGTAGQRCTTTRRLLVHEDVYDLVLSKLIAAYKKLRIGDPMDENVTIGPL----HTKGAVEMFKNCIDQVKSSXXXXXXXXXXXXXXXNFVQPTIVTNLAHDHPIVHNETFVPIIYVIKIKNLDQAITINNEVEQGLSSSLFTRDLSSIYRWLGPEGSDCGLVNVNIPTNGAEIGGAFGGEKMTGGGRESGSDSWKQYMRRSTCTINCGT 1659
            ++  N W  + SG  F    P+  + I +++ +   D ++ +      +    VWR + A  RG+++ ++     +    +A + SL  GK +      ++Q  I    +  G +   +G+  P + + +L   ++ P+GV G I  +NFP  +  W LA AL CGN+VV K +  T LT + V+ ++    KE   P  +V  L G G   G A+ +   I  V+FTGS   G  +Q+A   +   R  LE+GG N  I+  DA++D+            AGQ CT   R+ V E +YD  + + +   K+  +G P D     GP     H    +E  ++ I +    G K+E GG+ +G +G F++PT+ +++  D  I   E F P+  ++K K +++AI   N  + GL++++FT D++             G V VN   N       FGG KM+G GRE G    K+Y+   T T+   T
Sbjct:   40 IFINNEWHVSVSGKVFPVYNPATGEQICEVQEADKADVDKAVQAARLAFSLGSVWRRMDASERGKLLAKLADLVERDSVYLATIESLNSGKPFLPTLFVDLQGTIKTLRYFAGYADKIHGTSIPMDGE-YLTFTRYEPIGVCGQIIPWNFPLMMAAWKLAPALACGNTVVLKPSEETPLTCLYVAALV----KEAGFPPGVVNILPGFGPTAGAAIASHMGIDKVAFTGSTEVGKLIQEAAGRSNLKRVTLEMGGKNPNIIFADADLDLAVEQAHQGVFFNAGQCCTAGSRIYVEEPIYDEFVRRSVERAKRRIVGSPFDPTTEQGPQISREHQNRVLEYIQSGIQE----GAKLECGGKALGLKGFFIEPTVFSDVKDDMRIAKEEIFGPVQQIMKFKTVEEAIERANNSDYGLTAAVFTTDINKAMTV--STAMQAGTVWVNC-FNALSTQCPFGGYKMSGNGRELGESGLKEYLEIKTITMKTVT 515          

Query:  169 MIQSPEYSWLKDLGLKDYNNGVYDGNNWTASGTEFEQLCPSNNKIIAKIKMSSLEDCNRCIAETYKTNKVWRNLPAPYRGEIVRQIGYRFRQKKDIIAKLLSLEVGKIYAEGKGEVQEIIDICDFATGLSRMFNGSIFPSERQNHLLLEQWNPLGVVGVISAFNFPAAVFGWNLALALVCGNSVVWKGAPSTNLTTIAVSNIIIEVLKENNLPTSIVTALCGGTDVGQALVADKRIALVSFTGSCSAGAKVQQAVTNRFGRCLLELGGNNAIIVNHDANIDMVTRSVLFAAAGTAGQRCTTTRRLLVHEDVYDLVLSKLIAAYKKLRIGDPMDENVTIGPLHTKGAVEMFKNCIDQVKSSXXXXXXXXXXXXXXXNFVQPTIVTNLAHDHPIVHNETFVPIIYVIKIKNLDQAITINNEVEQGLSSSLFTRDLSSIYRWLGPEGSDCGLVNVNIPTNGAEIGGAFGGEKMTGGGRESGSDSWKQYMRRSTCTINCGTDLPLAQGIVFE 1692
            MIQSPEYSWLKDLG+KDYNNGVYDGNNWTASGTEFEQLCPSNNKIIAKIKMSSLEDCNRCIAETYKTNKVWRNLPAPYRGEIVRQIGYRFRQKKDIIAKLLSLEVGKIYAEGKGEVQEIIDICDFATGLSRMFNGSIFPSERQNHLLLEQWNPLGVVGVISAFNFPAAVFGWNLALALVCGNSVVWKGAPSTNLTTIAVSNIIIEVLKENNLPTSIVTALCGGTDVGQALVADKRIALVSFTGSCSAGAKVQQAVTNRFGRCLLELGGNNAIIVNHDANIDMVTRSVLFAAAGTAGQRCTTTRRLLVHEDVYDLVLSKLIAAYKKLRIGDPMDENVTIGPLHTKGAVEMFKNCIDQVKSSGGKIEFGGETIGTEGNFVQPTIVTNLAHDHPIVHNETFVPIIYVIKIKNLDQAITINNEVEQGLSSSLFTRDLSSIYRWLGPEGSDCGLVNVNIPTNGAEIGGAFGGEKMTGGGRESGSDSWKQYMRRSTCTINCGTDLPLAQGIVFE
Sbjct:    1 MIQSPEYSWLKDLGIKDYNNGVYDGNNWTASGTEFEQLCPSNNKIIAKIKMSSLEDCNRCIAETYKTNKVWRNLPAPYRGEIVRQIGYRFRQKKDIIAKLLSLEVGKIYAEGKGEVQEIIDICDFATGLSRMFNGSIFPSERQNHLLLEQWNPLGVVGVISAFNFPAAVFGWNLALALVCGNSVVWKGAPSTNLTTIAVSNIIIEVLKENNLPTSIVTALCGGTDVGQALVADKRIALVSFTGSCSAGAKVQQAVTNRFGRCLLELGGNNAIIVNHDANIDMVTRSVLFAAAGTAGQRCTTTRRLLVHEDVYDLVLSKLIAAYKKLRIGDPMDENVTIGPLHTKGAVEMFKNCIDQVKSSGGKIEFGGETIGTEGNFVQPTIVTNLAHDHPIVHNETFVPIIYVIKIKNLDQAITINNEVEQGLSSSLFTRDLSSIYRWLGPEGSDCGLVNVNIPTNGAEIGGAFGGEKMTGGGRESGSDSWKQYMRRSTCTINCGTDLPLAQGIVFE 508          

Query:  214 KDYNNGVYDGNNWTASGTEFEQLCPSNNKIIAKIKMSSLEDCNRCIAETYKTNKVWRNLPAPYRGEIVRQIGYRFRQKKDIIAKLLSLEVGKIYAEGKGEVQEIIDICDFATGLSRMFNGSIFPSERQNHLLLEQWNPLGVVGVISAFNFPAAVFGWNLALALVCGNSVVWKGAPSTNLTTIAVSNIIIEVLKENNLPTSIVTALCGGT----DVGQALVADKRIALVSFTGSCSAGAKVQQAVTNRFGRCLLELGGNNAIIVNHDANIDMVTRSVLFAAAGTAGQRCTTTRRLLVHEDVYDLVLSKLIAAYKKLRIGDPMDENVTIGPLHTKGAVEMFKNCIDQVKSSXXXX----XXXXXXXXXXXNFVQPTIVTNLAHDHPIVHNETFVPIIYVIKIKNLDQAITINNEVEQGLSSSLFTRDLSSIYRWLGPEGSDCGLVNVNIPTNGA--EIGGAFGGEKMTGGGRESGSDSWKQYMRR 1632
            K Y NG++  N     G  F+ + P+  ++I+ +   S+++ +  I   YK         A  R  +++Q+       +D I+ L++LE GK   E + EV+      ++     R   G I PS + +  L+    P+GVVG+I+ +NFP A+    L   L  G + + K A  T L+ +      IEV  E+ +P  ++  +         VG+A   D RI  ++FTGS   G  +         R   ELGGN   IV   A++++  +  L      +GQ C +  R+LVHE ++D  + KLI+   KL++G  ++++   GPL  + A+   +  I++   SG ++    +        +GNF QPT++T+ + DHP+  NE F P+  + KI +   A+ I N +  GL+  LF+ D   I+R    E    G++ VN    GA       F G K +G G ESG     +Y+ +
Sbjct:   25 KSYINGLWVTNE---DGLTFDVINPATGEVISTVPDLSVKEIDSGIESAYKAFNNSSKSTASQRSHLLKQLNDSLLAHEDEISSLITLENGKCLEEARTEVKYAASFLNWFAEEPRRIMGYIMPSPKLDQKLMILQQPIGVVGMITPWNFPLAMVTRKLGAILAAGCAAIIKPAEDTPLSLLK----FIEV-SESFIPPGMINVVTSSKLSCPSVGRAFCNDSRIKSITFTGSSEVGKILYAQSAETMKRLSFELGGNAPFIVFESADLNLAVKCALICKFRNSGQACISANRILVHESIHDEFVKKLISETSKLKVGYGLEKDNNQGPLINQDAIRKVEQLINRSVESGAQVKLGGKRAILEKYPKGNFFQPTVITDCSTDHPLFKNEIFGPVCAITKISDEKSAVRIANSLNTGLAGYLFSEDHRQIFRV--SEELQMGIIGVN---EGAVSHCEAPFSGWKESGLGTESGIFGIDEYLVK 494          

Query:  253 TASGTEFEQLCPSNNKIIAKIKMSSLEDCN---RCIAETYKTNKVWRNLPAPYRGEIVRQIGYRFRQKKDIIAKLLSLEVGKIYAEG-KGEVQEIIDICDFATGLSRMFNGSIFP--SERQN-HLLLEQWNPLGVVGVISAFNFPAAVFGWNLALALVCGNSVVWKGAPSTNLTTIAVSNIIIEVLKENNLPTSIVTALCG-GTDVGQALVADKRIALVSFTGSCSAGAKVQQA-VTNRFGRCLLELGGNNAIIVNHDANIDMVTRSVLFAAAGTAGQRCTTTRRLLVHEDVYDLVLSKLIAAYKKLRIGDPMDENVTIGPL-HTKGAVEMFKNCIDQVKSSXXXXXXXXXXXXXXXNFVQPTIVTNLAHDHPIVHNETFVPIIYVIKIKNLDQAITINNEVEQGLSSSLFTRDLSSIYRWLGPEGSDCGLVNVNIPTNGAEIGGAFGGEKMTGGGRESGSDSWKQYMRRSTCTI 1647
            + SG E++   PS+  +I ++  SS +D +   +   E ++  + W  + A  RG I+ ++     +  + +A L SL+ G +Y    K  +   I+   +  G      GS  P  + R N +L   +  P+GV G+I+ +N+P  +  W +A  L  GN+VV K A  T L ++    + +E       P+ ++  L G G   G A+     I  + FTGS + G  +  +   +   +C LELGG + +I+  D ++D   +S   +     G+ C    R+ V   ++D+ L  ++   KK++IGDP+D +V  GP  H    +++ + C   VK     +  G         F++PTI T++  D  I   E+F PI+ + K  ++D+ I   N+ E GL+S +FT D+S   R    +  D G V +N   N  ++   FGG K +G G++ G ++  +Y++  T T+
Sbjct:  446 SESGKEYDSKNPSDESVICRVSYSSKKDVDIAVKAAKEAFEFGE-WGKMSARDRGRILYKLADLMEEHAEELATLESLDSGAVYTLALKTHIGMSIETFRYFAGWCDKIQGSTIPISNARPNKNLSFTKKEPIGVCGIITPWNYPLMMLAWKVAACLAAGNTVVLKPAQVTPLASLKFCELSVEA----GFPSGVINVLPGSGAIAGTAISEHPDIRKLGFTGSTAIGQTIMSSCAKSNLKKCSLELGGKSPLIIFSDCDMDKAVKSACSSVFFNKGENCIAAGRIFVDVRIHDVFLKLVVEDVKKMKIGDPLDRSVDHGPQNHEIHLLKLLEFCDIGVKEGAKLVFGGKRCDRKGY-FMEPTIFTSVTDDMYIAREESFGPIMIISKFYDIDEVIVRANKTEYGLASGVFTNDISKALRV--ADAIDAGTVFINT-YNKTDVAAPFGGFKQSGFGKDLGQEALNEYLKTKTVTV 911          

Query:  253 TASGTEFEQLCPSNNKIIAKIKMSSLEDCN---RCIAETYKTNKVWRNLPAPYRGEIVRQIGYRFRQKKDIIAKLLSLEVGKIYAEG-KGEVQEIIDICDFATGLSRMFNGSIFP--SERQN-HLLLEQWNPLGVVGVISAFNFPAAVFGWNLALALVCGNSVVWKGAPSTNLTTIAVSNIIIEVLKENNLPTSIVTALCG-GTDVGQALVADKRIALVSFTGSCSAGAKVQQA-VTNRFGRCLLELGGNNAIIVNHDANIDMVTRSVLFAAAGTAGQRCTTTRRLLVHEDVYDLVLSKLIAAYKKLRIGDPMDENVTIGPL-HTKGAVEMFKNCIDQVKSSXXXXXXXXXXXXXXXNFVQPTIVTNLAHDHPIVHNETFVPIIYVIKIKNLDQAITINNEVEQGLSSSLFTRDLSSIYRWLGPEGSDCGLVNVNIPTNGAEIGGAFGGEKMTGGGRESGSDSWKQYMRRSTCTI 1647
            + SG E++   PS+  +I ++  SS +D +   +   E ++  + W  + A  RG I+ ++     +  + +A L SL+ G +Y    K  +   I+   +  G      GS  P  + R N +L   +  P+GV G+I+ +N+P  +  W +A  L  GN+VV K A  T L ++    + +E       P+ ++  L G G   G A+     I  + FTGS + G  +  +   +   +C LELGG + +I+  D ++D   +S   +     G+ C    R+ V   ++D+ L  ++   KK++IGDP+D +V  GP  H    +++ + C   VK     +  G         F++PTI T++  D  I   E+F PI+ + K  ++D+ I   N+ E GL+S +FT D+S   R    +  D G V +N   N  ++   FGG K +G G++ G ++  +Y++  T T+
Sbjct:  420 SESGKEYDSKNPSDESVICRVSYSSKKDVDIAVKAAKEAFEFGE-WGKMSARDRGRILYKLADLMEEHAEELATLESLDSGAVYTLALKTHIGMSIETFRYFAGWCDKIQGSTIPISNARPNKNLSFTKKEPIGVCGIITPWNYPLMMLAWKVAACLAAGNTVVLKPAQVTPLASLKFCELSVEA----GFPSGVINVLPGSGAIAGTAISEHPDIRKLGFTGSTAIGQTIMSSCAKSNLKKCSLELGGKSPLIIFSDCDMDKAVKSACSSVFFNKGENCIAAGRIFVDVRIHDVFLKLVVEDVKKMKIGDPLDRSVDHGPQNHEIHLLKLLEFCDIGVKEGAKLVFGGKRCDRKGY-FMEPTIFTSVTDDMYIAREESFGPIMIISKFYDIDEVIVRANKTEYGLASGVFTNDISKALRV--ADAIDAGTVFINT-YNKTDVAAPFGGFKQSGFGKDLGQEALNEYLKTKTVTV 885          

Query:  211 LKDYNNGVYDGNNW--TASGTEFEQLCPSNNKIIAKIKMSSLEDCNRCIA---ETYKTNKVWRNLPAPYRGEIVRQIGYRFRQKKDIIAKLLSLEVGKIYAEGKG-EVQEIIDICDFATGLSRMFNGSIFPSERQNHLLLEQWNPLGVVGVISAFNFPAAVFGWNLALALVCGNSVVWKGAPSTNLTTIAVSNIIIEVLKENNLPTSIVTALCG-GTDVGQALVADKRIALVSFTGSCSAGAKVQQAVT-NRFGRCLLELGGNNAIIVNHDANIDMVTRSVLFAAAGTAGQRCTTTRRLLVHEDVYDLVLSKLIAAYKKLRIGDPMDENVTIGPLHTKGAVEMFKNCIDQVKSSXXXXXXXXXXXXXXXNFVQPTIVTNLAHDHPIVHNETFVPIIYVIKIKNLDQAITINNEVEQGLSSSLFTRDLSSIYRWLGPEGSDCGLVNVNIPTNGAEIGGAFGGEKMTGGGRESGSDSWKQYMRRSTCTI 1647
            +K +   ++  N W  + S   F    P+  + I ++     ED ++ +    + ++    WR + A  RG ++ ++    R+  D +A L +L+ GK  +  +  +V+  I   ++  G +   +G + P  R +++   +  P+GV G I  +NFP  +  W LA AL  GN+VV K A  T LT    +N +  +  E   P  +V  + G G   G ALV   ++  ++FTGS   G  + +    N   R  LELGG +  IV  DA+ D   ++  FA     GQ C    R+ V E +YD  +  ++A  K   +G+P D NV  GP   +  +      ID  KS G ++  GG+ IG++G F++PTI T +     I   E F P++ ++K K+ ++ I   N  E GL++S+FT+D+         +    G V VN   +  +    FGG K +G GRE G      Y      TI
Sbjct:   36 IKVHYTKIFINNEWHDSVSKKTFPTKNPATGQDICQVAEGGKEDIDKAVTAANKAFQLGSPWRKMDAADRGSLMYKLAQLIRRDADYLAALETLDSGKPVSIARAADVELTIKCYEYYAGWADKNHGKVIPI-RGDYIGFTRHEPVGVCGQIIPWNFPLLMQAWKLAPALSMGNTVVLKTAEQTPLT----ANYVASLAAEAGFPPGVVNIVPGMGPTAGAALVTHPKVDKIAFTGSTEVGQIISKHCNENNIKRLTLELGGKSPNIVFADADFDNAVKTSYFALFFNMGQCCCAGSRIYVEEKIYDKFVEAMVAEAKSKVVGNPFD-NVDQGPQIDEEQMNKILGFIDSGKSEGAQMCTGGKQIGSKGFFIEPTIFTKVEDSMRIAKEEIFGPVMQIMKFKDTNEVIARANNNEYGLAASIFTQDIDKSLHVT--QSLRAGTVWVNC-YDVFDAAAPFGGYKSSGVGRELGEYGLSNYTEVKMVTI 513