Dynein light chain

Overview
NameDynein light chain
Smed IDSMED30013082
Length (bp)606
Neoblast Clusters

Zeng et. al., 2018



▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)



Explore this single cell expression dataset with our NB Cluster Shiny App



 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of Dynein light chain (SMED30013082) t-SNE clustered cells

Violin plots show distribution of expression levels for Dynein light chain (SMED30013082) in cells (dots) of each of the 12 neoblast clusters.

 

back to top

 

Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of Dynein light chain (SMED30013082) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for Dynein light chain (SMED30013082) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

back to top

 

Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
Sort Descending | Sort Ascending | Only Non-Zero Values | Tile/Chart | Reset

Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

back to top
Anatomical Expression

PAGE et. al., 2020



SMED30013082

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 6

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
pharynxSMED30013082h1SMcG0021859 dd_Smed_v4_1888_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
epidermisSMED30013082h1SMcG0021859 dd_Smed_v4_1888_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
cephalic gangliaSMED30013082h1SMcG0021859 dd_Smed_v4_1888_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
head regionSMED30013082h1SMcG0021859 dd_Smed_v6_1888_0_1dd_Smed_v6PMID:28171748
Stückemann et al., 2017		whole organism asexual adult RNA-sequencing evidence
epidermisSMED30013082h1SMcG0021859 dd_Smed_v4_1888_0_1dd_Smed_v4PMID:28292427
Wurtzel et al., 2017		whole organism asexual adult single-cell RNA-sequencing evidence
Category 4 cellSMED30013082h1SMcG0021859 dd_Smed_v4_1888_0_1dd_Smed_v4PMID:28292427
Wurtzel et al., 2017		whole organism asexual adult single-cell RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
[Close]
BLAST of Dynein light chain vs. Ensembl Human
Match: DYNLL1 (dynein light chain LC8-type 1 [Source:HGNC Symbol;Acc:HGNC:15476])

HSP 1 Score: 50.447 bits (119), Expect = 4.643e-8
Identity = 26/84 (30.95%), Postives = 46/84 (54.76%), Query Frame = 3 
Query:  303 IIKEDDNMPQNLKDAIINTSIDALNNYEKESQMAKHIKIFLDDNFGKVWHAVVGKSQFGSNISHLPESFMHYKIEDHAFLIFKT 554
            +IK  D M + ++   +  +  AL  Y  E  +A HIK   D  +   WH +VG++ FGS ++H  + F+++ +   A L+FK+
Sbjct:    7 VIKNAD-MSEEMQQDSVECATQALEKYNIEKDIAAHIKKEFDKKYNPTWHCIVGRN-FGSYVTHETKHFIYFYLGQVAILLFKS 88
[Close]
BLAST of Dynein light chain vs. Ensembl Human
Match: DYNLL1 (dynein light chain LC8-type 1 [Source:HGNC Symbol;Acc:HGNC:15476])

HSP 1 Score: 50.447 bits (119), Expect = 4.643e-8
Identity = 26/84 (30.95%), Postives = 46/84 (54.76%), Query Frame = 3 
Query:  303 IIKEDDNMPQNLKDAIINTSIDALNNYEKESQMAKHIKIFLDDNFGKVWHAVVGKSQFGSNISHLPESFMHYKIEDHAFLIFKT 554
            +IK  D M + ++   +  +  AL  Y  E  +A HIK   D  +   WH +VG++ FGS ++H  + F+++ +   A L+FK+
Sbjct:    7 VIKNAD-MSEEMQQDSVECATQALEKYNIEKDIAAHIKKEFDKKYNPTWHCIVGRN-FGSYVTHETKHFIYFYLGQVAILLFKS 88
[Close]
BLAST of Dynein light chain vs. Ensembl Human
Match: DYNLL1 (dynein light chain LC8-type 1 [Source:HGNC Symbol;Acc:HGNC:15476])

HSP 1 Score: 50.447 bits (119), Expect = 4.643e-8
Identity = 26/84 (30.95%), Postives = 46/84 (54.76%), Query Frame = 3 
Query:  303 IIKEDDNMPQNLKDAIINTSIDALNNYEKESQMAKHIKIFLDDNFGKVWHAVVGKSQFGSNISHLPESFMHYKIEDHAFLIFKT 554
            +IK  D M + ++   +  +  AL  Y  E  +A HIK   D  +   WH +VG++ FGS ++H  + F+++ +   A L+FK+
Sbjct:    7 VIKNAD-MSEEMQQDSVECATQALEKYNIEKDIAAHIKKEFDKKYNPTWHCIVGRN-FGSYVTHETKHFIYFYLGQVAILLFKS 88
[Close]
BLAST of Dynein light chain vs. Ensembl Human
Match: DYNLL1 (dynein light chain LC8-type 1 [Source:HGNC Symbol;Acc:HGNC:15476])

HSP 1 Score: 50.447 bits (119), Expect = 4.643e-8
Identity = 26/84 (30.95%), Postives = 46/84 (54.76%), Query Frame = 3 
Query:  303 IIKEDDNMPQNLKDAIINTSIDALNNYEKESQMAKHIKIFLDDNFGKVWHAVVGKSQFGSNISHLPESFMHYKIEDHAFLIFKT 554
            +IK  D M + ++   +  +  AL  Y  E  +A HIK   D  +   WH +VG++ FGS ++H  + F+++ +   A L+FK+
Sbjct:    7 VIKNAD-MSEEMQQDSVECATQALEKYNIEKDIAAHIKKEFDKKYNPTWHCIVGRN-FGSYVTHETKHFIYFYLGQVAILLFKS 88
[Close]
BLAST of Dynein light chain vs. Ensembl Human
Match: DYNLL1 (dynein light chain LC8-type 1 [Source:HGNC Symbol;Acc:HGNC:15476])

HSP 1 Score: 50.447 bits (119), Expect = 4.643e-8
Identity = 26/84 (30.95%), Postives = 46/84 (54.76%), Query Frame = 3 
Query:  303 IIKEDDNMPQNLKDAIINTSIDALNNYEKESQMAKHIKIFLDDNFGKVWHAVVGKSQFGSNISHLPESFMHYKIEDHAFLIFKT 554
            +IK  D M + ++   +  +  AL  Y  E  +A HIK   D  +   WH +VG++ FGS ++H  + F+++ +   A L+FK+
Sbjct:    7 VIKNAD-MSEEMQQDSVECATQALEKYNIEKDIAAHIKKEFDKKYNPTWHCIVGRN-FGSYVTHETKHFIYFYLGQVAILLFKS 88
[Close]
BLAST of Dynein light chain vs. Ensembl Celegans
Match: dlc-5 (Dynein Light Chain [Source:UniProtKB/TrEMBL;Acc:Q65XS9])

HSP 1 Score: 62.003 bits (149), Expect = 6.020e-12
Identity = 25/78 (32.05%), Postives = 48/78 (61.54%), Query Frame = 3 
Query:  321 NMPQNLKDAIINTSIDALNNYEKESQMAKHIKIFLDDNFGKVWHAVVGKSQFGSNISHLPESFMHYKIEDHAFLIFKT 554
             MP++++    + +  ++  Y  E  +A+H+K+  D  +G  WH + GK  FGS ++  P+SF++++I   AF++FKT
Sbjct:   64 RMPRHMEQEACSLAAKSIMTYHLEHDIARHLKMAFDREYGPDWHCICGK-HFGSFVTFEPDSFIYFRIGTIAFMLFKT 140
[Close]
BLAST of Dynein light chain vs. Ensembl Celegans
Match: dlc-1 (Dynein light chain 1, cytoplasmic [Source:UniProtKB/Swiss-Prot;Acc:Q22799])

HSP 1 Score: 49.2914 bits (116), Expect = 4.412e-8
Identity = 26/84 (30.95%), Postives = 47/84 (55.95%), Query Frame = 3 
Query:  303 IIKEDDNMPQNLKDAIINTSIDALNNYEKESQMAKHIKIFLDDNFGKVWHAVVGKSQFGSNISHLPESFMHYKIEDHAFLIFKT 554
            +IK  D M  +++   I+ +  AL  Y  E  +A +IK   D  +   WH +VG++ FGS ++H  + F+++ +   A L+FK+
Sbjct:    7 VIKNAD-MSDDMQQDAIDCATQALEKYNIEKDIAAYIKKEFDKKYNPTWHCIVGRN-FGSYVTHETKHFIYFYLGQVAILLFKS 88
[Close]
BLAST of Dynein light chain vs. Ensembl Celegans
Match: dlc-1 (Dynein light chain 1, cytoplasmic [Source:UniProtKB/Swiss-Prot;Acc:Q22799])

HSP 1 Score: 49.2914 bits (116), Expect = 4.412e-8
Identity = 26/84 (30.95%), Postives = 47/84 (55.95%), Query Frame = 3 
Query:  303 IIKEDDNMPQNLKDAIINTSIDALNNYEKESQMAKHIKIFLDDNFGKVWHAVVGKSQFGSNISHLPESFMHYKIEDHAFLIFKT 554
            +IK  D M  +++   I+ +  AL  Y  E  +A +IK   D  +   WH +VG++ FGS ++H  + F+++ +   A L+FK+
Sbjct:    7 VIKNAD-MSDDMQQDAIDCATQALEKYNIEKDIAAYIKKEFDKKYNPTWHCIVGRN-FGSYVTHETKHFIYFYLGQVAILLFKS 88
[Close]
BLAST of Dynein light chain vs. Ensembl Celegans
Match: dlc-1 (Dynein light chain 1, cytoplasmic [Source:UniProtKB/Swiss-Prot;Acc:Q22799])

HSP 1 Score: 49.2914 bits (116), Expect = 4.412e-8
Identity = 26/84 (30.95%), Postives = 47/84 (55.95%), Query Frame = 3 
Query:  303 IIKEDDNMPQNLKDAIINTSIDALNNYEKESQMAKHIKIFLDDNFGKVWHAVVGKSQFGSNISHLPESFMHYKIEDHAFLIFKT 554
            +IK  D M  +++   I+ +  AL  Y  E  +A +IK   D  +   WH +VG++ FGS ++H  + F+++ +   A L+FK+
Sbjct:    7 VIKNAD-MSDDMQQDAIDCATQALEKYNIEKDIAAYIKKEFDKKYNPTWHCIVGRN-FGSYVTHETKHFIYFYLGQVAILLFKS 88
[Close]
BLAST of Dynein light chain vs. Ensembl Celegans
Match: dlc-2 (Probable dynein light chain 2, cytoplasmic [Source:UniProtKB/Swiss-Prot;Acc:Q21557])

HSP 1 Score: 42.743 bits (99), Expect = 9.635e-6
Identity = 26/88 (29.55%), Postives = 43/88 (48.86%), Query Frame = 3 
Query:  291 ENVDIIKEDDNMPQNLKDAIINTSIDALNNYEKESQMAKHIKIFLDDNFGKVWHAVVGKSQFGSNISHLPESFMHYKIEDHAFLIFKT 554
            E +++ + D   PQ  +D +I+   +A   Y  +  +A  +K  LD  FG  WH + GK  FGS +S+    F+  K      +I+K 
Sbjct:    4 EKIEVKETDMEDPQ--RDMVISVVREAQRLYNIDKDVAAFVKEELDKKFGATWHVICGKC-FGSRVSYEMGHFILLKCNKVNVMIYKC 88
[Close]
BLAST of Dynein light chain vs. Ensembl Fly
Match: ctp (gene:FBgn0011760 transcript:FBtr0070706)

HSP 1 Score: 49.2914 bits (116), Expect = 5.054e-8
Identity = 25/84 (29.76%), Postives = 46/84 (54.76%), Query Frame = 3 
Query:  303 IIKEDDNMPQNLKDAIINTSIDALNNYEKESQMAKHIKIFLDDNFGKVWHAVVGKSQFGSNISHLPESFMHYKIEDHAFLIFKT 554
            +IK  D M + ++   ++ +  AL  Y  E  +A +IK   D  +   WH +VG++ FGS ++H    F+++ +   A L+FK+
Sbjct:    7 VIKNAD-MSEEMQQDAVDCATQALEKYNIEKDIAAYIKKEFDKKYNPTWHCIVGRN-FGSYVTHETRHFIYFYLGQVAILLFKS 88
[Close]
BLAST of Dynein light chain vs. Ensembl Fly
Match: ctp (gene:FBgn0011760 transcript:FBtr0070704)

HSP 1 Score: 49.2914 bits (116), Expect = 5.054e-8
Identity = 25/84 (29.76%), Postives = 46/84 (54.76%), Query Frame = 3 
Query:  303 IIKEDDNMPQNLKDAIINTSIDALNNYEKESQMAKHIKIFLDDNFGKVWHAVVGKSQFGSNISHLPESFMHYKIEDHAFLIFKT 554
            +IK  D M + ++   ++ +  AL  Y  E  +A +IK   D  +   WH +VG++ FGS ++H    F+++ +   A L+FK+
Sbjct:    7 VIKNAD-MSEEMQQDAVDCATQALEKYNIEKDIAAYIKKEFDKKYNPTWHCIVGRN-FGSYVTHETRHFIYFYLGQVAILLFKS 88
[Close]
BLAST of Dynein light chain vs. Ensembl Fly
Match: ctp (gene:FBgn0011760 transcript:FBtr0307065)

HSP 1 Score: 49.2914 bits (116), Expect = 5.054e-8
Identity = 25/84 (29.76%), Postives = 46/84 (54.76%), Query Frame = 3 
Query:  303 IIKEDDNMPQNLKDAIINTSIDALNNYEKESQMAKHIKIFLDDNFGKVWHAVVGKSQFGSNISHLPESFMHYKIEDHAFLIFKT 554
            +IK  D M + ++   ++ +  AL  Y  E  +A +IK   D  +   WH +VG++ FGS ++H    F+++ +   A L+FK+
Sbjct:    7 VIKNAD-MSEEMQQDAVDCATQALEKYNIEKDIAAYIKKEFDKKYNPTWHCIVGRN-FGSYVTHETRHFIYFYLGQVAILLFKS 88
[Close]
BLAST of Dynein light chain vs. Ensembl Fly
Match: ctp (gene:FBgn0011760 transcript:FBtr0070707)

HSP 1 Score: 49.2914 bits (116), Expect = 5.054e-8
Identity = 25/84 (29.76%), Postives = 46/84 (54.76%), Query Frame = 3 
Query:  303 IIKEDDNMPQNLKDAIINTSIDALNNYEKESQMAKHIKIFLDDNFGKVWHAVVGKSQFGSNISHLPESFMHYKIEDHAFLIFKT 554
            +IK  D M + ++   ++ +  AL  Y  E  +A +IK   D  +   WH +VG++ FGS ++H    F+++ +   A L+FK+
Sbjct:    7 VIKNAD-MSEEMQQDAVDCATQALEKYNIEKDIAAYIKKEFDKKYNPTWHCIVGRN-FGSYVTHETRHFIYFYLGQVAILLFKS 88
[Close]
BLAST of Dynein light chain vs. Ensembl Fly
Match: Cdlc2 (gene:FBgn0026141 transcript:FBtr0077924)

HSP 1 Score: 47.7506 bits (112), Expect = 1.796e-7
Identity = 25/84 (29.76%), Postives = 45/84 (53.57%), Query Frame = 3 
Query:  303 IIKEDDNMPQNLKDAIINTSIDALNNYEKESQMAKHIKIFLDDNFGKVWHAVVGKSQFGSNISHLPESFMHYKIEDHAFLIFKT 554
            +IK  D M + ++   ++ +  AL  Y  E  +A  IK   D  +   WH +VG++ FGS ++H    F+++ +   A L+FK+
Sbjct:    7 VIKNAD-MSEEMQQDAVDCATQALEKYNIEKDIAAFIKKEFDKKYNPTWHCIVGRN-FGSYVTHETRHFIYFYLGQVAILLFKS 88
[Close]
BLAST of Dynein light chain vs. Ensembl Zebrafish
Match: dynll2a (dynein, light chain, LC8-type 2a [Source:ZFIN;Acc:ZDB-GENE-030828-11])

HSP 1 Score: 48.9062 bits (115), Expect = 8.849e-8
Identity = 24/84 (28.57%), Postives = 48/84 (57.14%), Query Frame = 3 
Query:  303 IIKEDDNMPQNLKDAIINTSIDALNNYEKESQMAKHIKIFLDDNFGKVWHAVVGKSQFGSNISHLPESFMHYKIEDHAFLIFKT 554
            +IK  D M ++++   ++ +  A+  Y  E  +A +IK   D  +   WH +VG++ FGS ++H  + F+++ +   A L+FK+
Sbjct:    7 VIKNAD-MSEDMQQDAVDCATQAMEKYNIEKDIAAYIKKEFDKKYNPTWHCIVGRN-FGSYVTHETKHFIYFYLGQVAILLFKS 88
[Close]
BLAST of Dynein light chain vs. Ensembl Zebrafish
Match: dynll2b (dynein, light chain, LC8-type 2b [Source:ZFIN;Acc:ZDB-GENE-050320-132])

HSP 1 Score: 48.9062 bits (115), Expect = 8.849e-8
Identity = 24/84 (28.57%), Postives = 48/84 (57.14%), Query Frame = 3 
Query:  303 IIKEDDNMPQNLKDAIINTSIDALNNYEKESQMAKHIKIFLDDNFGKVWHAVVGKSQFGSNISHLPESFMHYKIEDHAFLIFKT 554
            +IK  D M ++++   ++ +  A+  Y  E  +A +IK   D  +   WH +VG++ FGS ++H  + F+++ +   A L+FK+
Sbjct:    7 VIKNAD-MSEDMQQDAVDCATQAMEKYNIEKDIAAYIKKEFDKKYNPTWHCIVGRN-FGSYVTHETKHFIYFYLGQVAILLFKS 88
[Close]
BLAST of Dynein light chain vs. Ensembl Zebrafish
Match: dynll2a (dynein, light chain, LC8-type 2a [Source:ZFIN;Acc:ZDB-GENE-030828-11])

HSP 1 Score: 48.9062 bits (115), Expect = 8.849e-8
Identity = 24/84 (28.57%), Postives = 48/84 (57.14%), Query Frame = 3 
Query:  303 IIKEDDNMPQNLKDAIINTSIDALNNYEKESQMAKHIKIFLDDNFGKVWHAVVGKSQFGSNISHLPESFMHYKIEDHAFLIFKT 554
            +IK  D M ++++   ++ +  A+  Y  E  +A +IK   D  +   WH +VG++ FGS ++H  + F+++ +   A L+FK+
Sbjct:    7 VIKNAD-MSEDMQQDAVDCATQAMEKYNIEKDIAAYIKKEFDKKYNPTWHCIVGRN-FGSYVTHETKHFIYFYLGQVAILLFKS 88
[Close]
BLAST of Dynein light chain vs. Ensembl Zebrafish
Match: dynll1 (dynein, light chain, LC8-type 1 [Source:ZFIN;Acc:ZDB-GENE-040426-1961])

HSP 1 Score: 48.9062 bits (115), Expect = 1.075e-7
Identity = 25/84 (29.76%), Postives = 46/84 (54.76%), Query Frame = 3 
Query:  303 IIKEDDNMPQNLKDAIINTSIDALNNYEKESQMAKHIKIFLDDNFGKVWHAVVGKSQFGSNISHLPESFMHYKIEDHAFLIFKT 554
            +IK  D M + ++   +  +  AL  Y  E  +A +IK   D  +   WH +VG++ FGS ++H  + F+++ +   A L+FK+
Sbjct:    7 VIKNAD-MSEEMQQDAVECATQALEKYNIEKDIAAYIKKEFDKKYNPTWHCIVGRN-FGSYVTHETKHFIYFYLGQVAILLFKS 88
[Close]
BLAST of Dynein light chain vs. Ensembl Zebrafish
Match: dynll1 (dynein, light chain, LC8-type 1 [Source:ZFIN;Acc:ZDB-GENE-040426-1961])

HSP 1 Score: 48.9062 bits (115), Expect = 1.075e-7
Identity = 25/84 (29.76%), Postives = 46/84 (54.76%), Query Frame = 3 
Query:  303 IIKEDDNMPQNLKDAIINTSIDALNNYEKESQMAKHIKIFLDDNFGKVWHAVVGKSQFGSNISHLPESFMHYKIEDHAFLIFKT 554
            +IK  D M + ++   +  +  AL  Y  E  +A +IK   D  +   WH +VG++ FGS ++H  + F+++ +   A L+FK+
Sbjct:    7 VIKNAD-MSEEMQQDAVECATQALEKYNIEKDIAAYIKKEFDKKYNPTWHCIVGRN-FGSYVTHETKHFIYFYLGQVAILLFKS 88
[Close]
BLAST of Dynein light chain vs. Ensembl Xenopus
Match: dynll2 (dynein light chain LC8-type 2 [Source:NCBI gene;Acc:100038056])

HSP 1 Score: 48.9062 bits (115), Expect = 1.355e-7
Identity = 24/84 (28.57%), Postives = 48/84 (57.14%), Query Frame = 3 
Query:  303 IIKEDDNMPQNLKDAIINTSIDALNNYEKESQMAKHIKIFLDDNFGKVWHAVVGKSQFGSNISHLPESFMHYKIEDHAFLIFKT 554
            +IK  D M ++++   ++ +  A+  Y  E  +A +IK   D  +   WH +VG++ FGS ++H  + F+++ +   A L+FK+
Sbjct:    7 VIKNAD-MSEDMQQDAVDCATQAMEKYNIEKDIAAYIKKEFDKKYNPTWHCIVGRN-FGSYVTHETKHFIYFYLGQVAILLFKS 88
[Close]
BLAST of Dynein light chain vs. Ensembl Xenopus
Match: dynll1 (dynein light chain LC8-type 1 [Source:NCBI gene;Acc:448652])

HSP 1 Score: 46.595 bits (109), Expect = 9.137e-7
Identity = 25/88 (28.41%), Postives = 47/88 (53.41%), Query Frame = 3 
Query:  291 ENVDIIKEDDNMPQNLKDAIINTSIDALNNYEKESQMAKHIKIFLDDNFGKVWHAVVGKSQFGSNISHLPESFMHYKIEDHAFLIFKT 554
            E   +IK  D M + ++   ++ +  AL  +  E  +A  IK   D  +   WH +VG++ FGS ++H  + F+++ +   A L+FK+
Sbjct:    3 ERKAVIKNAD-MSEEMQQDAVDCATQALEKFNIEKDIAAFIKKEFDKKYNPTWHCIVGRN-FGSYVTHETKHFIYFYLGQVAILLFKS 88
[Close]
BLAST of Dynein light chain vs. Ensembl Mouse
Match: BC048507 (cDNA sequence BC048507 [Source:MGI Symbol;Acc:MGI:3040680])

HSP 1 Score: 51.6026 bits (122), Expect = 1.083e-8
Identity = 26/84 (30.95%), Postives = 47/84 (55.95%), Query Frame = 3 
Query:  303 IIKEDDNMPQNLKDAIINTSIDALNNYEKESQMAKHIKIFLDDNFGKVWHAVVGKSQFGSNISHLPESFMHYKIEDHAFLIFKT 554
            +IK  D M + ++   +  +I AL  Y  E  +A HIK   D  +   WH +VG++ FGS +++  + F+++ +   A L+FK+
Sbjct:    7 VIKTVD-MSEEMQQDSVRCAIQALEKYSTEKDIAAHIKKEFDKKYNPTWHCIVGRN-FGSYVTYETKHFVYFYLGQVAILLFKS 88
[Close]
BLAST of Dynein light chain vs. Ensembl Mouse
Match: Dynll1 (dynein light chain LC8-type 1 [Source:MGI Symbol;Acc:MGI:1861457])

HSP 1 Score: 50.447 bits (119), Expect = 3.188e-8
Identity = 26/84 (30.95%), Postives = 46/84 (54.76%), Query Frame = 3 
Query:  303 IIKEDDNMPQNLKDAIINTSIDALNNYEKESQMAKHIKIFLDDNFGKVWHAVVGKSQFGSNISHLPESFMHYKIEDHAFLIFKT 554
            +IK  D M + ++   +  +  AL  Y  E  +A HIK   D  +   WH +VG++ FGS ++H  + F+++ +   A L+FK+
Sbjct:    7 VIKNAD-MSEEMQQDSVECATQALEKYNIEKDIAAHIKKEFDKKYNPTWHCIVGRN-FGSYVTHETKHFIYFYLGQVAILLFKS 88
[Close]
BLAST of Dynein light chain vs. Ensembl Mouse
Match: Dynll1 (dynein light chain LC8-type 1 [Source:MGI Symbol;Acc:MGI:1861457])

HSP 1 Score: 50.447 bits (119), Expect = 3.188e-8
Identity = 26/84 (30.95%), Postives = 46/84 (54.76%), Query Frame = 3 
Query:  303 IIKEDDNMPQNLKDAIINTSIDALNNYEKESQMAKHIKIFLDDNFGKVWHAVVGKSQFGSNISHLPESFMHYKIEDHAFLIFKT 554
            +IK  D M + ++   +  +  AL  Y  E  +A HIK   D  +   WH +VG++ FGS ++H  + F+++ +   A L+FK+
Sbjct:    7 VIKNAD-MSEEMQQDSVECATQALEKYNIEKDIAAHIKKEFDKKYNPTWHCIVGRN-FGSYVTHETKHFIYFYLGQVAILLFKS 88
[Close]
BLAST of Dynein light chain vs. Ensembl Mouse
Match: Dynll2 (dynein light chain LC8-type 2 [Source:MGI Symbol;Acc:MGI:1915347])

HSP 1 Score: 48.9062 bits (115), Expect = 1.026e-7
Identity = 24/84 (28.57%), Postives = 48/84 (57.14%), Query Frame = 3 
Query:  303 IIKEDDNMPQNLKDAIINTSIDALNNYEKESQMAKHIKIFLDDNFGKVWHAVVGKSQFGSNISHLPESFMHYKIEDHAFLIFKT 554
            +IK  D M ++++   ++ +  A+  Y  E  +A +IK   D  +   WH +VG++ FGS ++H  + F+++ +   A L+FK+
Sbjct:    7 VIKNAD-MSEDMQQDAVDCATQAMEKYNIEKDIAAYIKKEFDKKYNPTWHCIVGRN-FGSYVTHETKHFIYFYLGQVAILLFKS 88
[Close]
BLAST of Dynein light chain vs. Ensembl Mouse
Match: Dynll2 (dynein light chain LC8-type 2 [Source:MGI Symbol;Acc:MGI:1915347])

HSP 1 Score: 48.9062 bits (115), Expect = 1.026e-7
Identity = 24/84 (28.57%), Postives = 48/84 (57.14%), Query Frame = 3 
Query:  303 IIKEDDNMPQNLKDAIINTSIDALNNYEKESQMAKHIKIFLDDNFGKVWHAVVGKSQFGSNISHLPESFMHYKIEDHAFLIFKT 554
            +IK  D M ++++   ++ +  A+  Y  E  +A +IK   D  +   WH +VG++ FGS ++H  + F+++ +   A L+FK+
Sbjct:    7 VIKNAD-MSEDMQQDAVDCATQAMEKYNIEKDIAAYIKKEFDKKYNPTWHCIVGRN-FGSYVTHETKHFIYFYLGQVAILLFKS 88
[Close]
BLAST of Dynein light chain vs. UniProt/SwissProt
Match: sp|Q6BZF8|DYL1_DEBHA (Dynein light chain 1, cytoplasmic OS=Debaryomyces hansenii (strain ATCC 36239 / CBS 767 / JCM 1990 / NBRC 0083 / IGC 2968) OX=284592 GN=DYN2 PE=3 SV=1)

HSP 1 Score: 62.3882 bits (150), Expect = 6.660e-12
Identity = 34/88 (38.64%), Postives = 53/88 (60.23%), Query Frame = 3 
Query:  291 ENVDIIKEDDNMPQNLKDAIINTSIDALNNYEKESQMAKHIKIFLDDNFGKVWHAVVGKSQFGSNISHLPESFMHYKIEDHAFLIFKT 554
            E   I+K  D +P+ ++  I   S +A++NY+ E  +A ++K  LD  +G  WH +VGKS FGS ++H    F ++ I   AFLIFK+
Sbjct:    5 EQEPILKASD-LPEEMQTRIFELSNEAVSNYKIEKDIATYLKKELDQLYGATWHVIVGKS-FGSYVTHEQGFFTYFYIGQLAFLIFKS 90
[Close]
BLAST of Dynein light chain vs. UniProt/SwissProt
Match: sp|Q02647|DYL1_YEAST (Dynein light chain 1, cytoplasmic OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) OX=559292 GN=DYN2 PE=1 SV=1)

HSP 1 Score: 61.6178 bits (148), Expect = 1.665e-11
Identity = 34/88 (38.64%), Postives = 53/88 (60.23%), Query Frame = 3 
Query:  291 ENVDIIKEDDNMPQNLKDAIINTSIDALNNYEKESQMAKHIKIFLDDNFGKVWHAVVGKSQFGSNISHLPESFMHYKIEDHAFLIFKT 554
            ++  I+K  D +   LK+ I+  S DAL+ Y+ E  +A  +K  LD  +G  WH +VGK+ FGS ++H    F+++ I   AFL+FKT
Sbjct:    6 KSTPIVKASD-ITDKLKEDILTISKDALDKYQLERDIAGTVKKQLDVKYGNTWHVIVGKN-FGSYVTHEKGHFVYFYIGPLAFLVFKT 91
[Close]
BLAST of Dynein light chain vs. UniProt/SwissProt
Match: sp|Q759T0|DYL1_ASHGO (Dynein light chain 1, cytoplasmic OS=Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056) OX=284811 GN=DYN2 PE=3 SV=1)

HSP 1 Score: 60.8474 bits (146), Expect = 2.771e-11
Identity = 32/84 (38.10%), Postives = 51/84 (60.71%), Query Frame = 3 
Query:  303 IIKEDDNMPQNLKDAIINTSIDALNNYEKESQMAKHIKIFLDDNFGKVWHAVVGKSQFGSNISHLPESFMHYKIEDHAFLIFKT 554
            I+K  D +   L+D I   S+ A+  ++ E ++A +IK  LD   G+ WH +VGK+ FGS ++H    F+++ I   AFL+FKT
Sbjct:    6 ILKASD-ITDELRDEIFGISVQAVEQFQLEREVAAYIKKELDSKHGQTWHVIVGKN-FGSYVTHEKGHFIYFYIGPLAFLVFKT 87
[Close]
BLAST of Dynein light chain vs. UniProt/SwissProt
Match: sp|Q94748|DYL2_SCHMA (Probable dynein light chain OS=Schistosoma mansoni OX=6183 PE=3 SV=1)

HSP 1 Score: 60.4622 bits (145), Expect = 3.394e-11
Identity = 30/88 (34.09%), Postives = 55/88 (62.50%), Query Frame = 3 
Query:  291 ENVDIIKEDDNMPQNLKDAIINTSIDALNNYEKESQMAKHIKIFLDDNFGKVWHAVVGKSQFGSNISHLPESFMHYKIEDHAFLIFKT 554
            E   +IK  D M +++++  ++T+  AL+ YE E  +A +IK   D  +   WH +VGK  FGS ++H  + F+++ +++ AFL+FK+
Sbjct:    3 ERKAVIKNAD-MHEDMQETAVHTAAAALDKYEIEKDVAAYIKKEFDRKYNPNWHCIVGK-HFGSYVTHETQHFIYFYLQERAFLLFKS 88
[Close]
BLAST of Dynein light chain vs. UniProt/SwissProt
Match: sp|Q6CWX4|DYL1_KLULA (Dynein light chain 1, cytoplasmic OS=Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37) OX=284590 GN=DYN2 PE=3 SV=1)

HSP 1 Score: 58.9214 bits (141), Expect = 1.158e-10
Identity = 33/84 (39.29%), Postives = 52/84 (61.90%), Query Frame = 3 
Query:  303 IIKEDDNMPQNLKDAIINTSIDALNNYEKESQMAKHIKIFLDDNFGKVWHAVVGKSQFGSNISHLPESFMHYKIEDHAFLIFKT 554
            ++K  D +   L+D I   S +A  NY+ E ++A +IK  LD + G+ WH +VGK+ FGS ++H    F+++ I   AFL+FKT
Sbjct:    5 VLKASD-ITDELRDEIFELSSNATANYKLEREIAAYIKKQLDVSQGETWHVIVGKN-FGSYVTHEKGYFVYFYIGPLAFLVFKT 86
[Close]
BLAST of Dynein light chain vs. TrEMBL
Match: A0A267EIW9 (Dynein light chain OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig005207g1 PE=3 SV=1)

HSP 1 Score: 123.25 bits (308), Expect = 7.011e-32
Identity = 66/175 (37.71%), Postives = 102/175 (58.29%), Query Frame = 3 
Query:   45 MELLKIFNEIDVGRTGIITEEQLLDFQER-NGLNNFAEKWLNMFDVENEGKIRIENFASTVGLEP-EDYVDQTIQNHEES--GQFIENVDIIKEDDNMPQNLKDAIINTSIDALNNYEKESQMAKHIKIFLDDNFGKVWHAVVGKSQFGSNISHLPESFMHYKIEDHAFLIFKTP 557
            M+ L  F +ID   +G IT E+L  +  R N  + F EKWL +FD +N G I IE F  T+GL P ++Y+++   N E+S  G  ++ V II ED  +  + K+ I+  +  A   +  E  +A+H+K  LDD FG+ WH +VG+ Q+GS  +H   S  H+ +  +A L++KTP
Sbjct:    1 MDFLHAFEDIDSDFSGEITTEELEAYCRRHNYEDRFVEKWLRLFDHDNSGTITIEEFCDTLGLVPKQEYMEKVQTNREKSEGGGIMDGVKIITEDPELSDSTKEEIVRIARQAQEQFVNERDIARHMKARLDDMFGRAWHVIVGRYQYGSFCTHETGSLFHFYVLRNAVLVWKTP 175
[Close]
BLAST of Dynein light chain vs. TrEMBL
Match: A0A1I8IZR3 (Uncharacterized protein OS=Macrostomum lignano OX=282301 PE=4 SV=1)

HSP 1 Score: 124.02 bits (310), Expect = 8.506e-30
Identity = 66/177 (37.29%), Postives = 103/177 (58.19%), Query Frame = 3 
Query:   39 LPMELLKIFNEIDVGRTGIITEEQLLDFQER-NGLNNFAEKWLNMFDVENEGKIRIENFASTVGLEP-EDYVDQTIQNHEES--GQFIENVDIIKEDDNMPQNLKDAIINTSIDALNNYEKESQMAKHIKIFLDDNFGKVWHAVVGKSQFGSNISHLPESFMHYKIEDHAFLIFKTP 557
            + M+ L  F +ID   +G IT E+L  +  R N  + F EKWL +FD +N G I IE F  T+GL P ++Y+++   N E+S  G  ++ V II ED  +  + K+ I+  +  A   +  E  +A+H+K  LDD FG+ WH +VG+ Q+GS  +H   S  H+ +  +A L++KTP
Sbjct:  281 ISMDFLHAFEDIDSDFSGEITTEELEAYCRRHNYEDRFVEKWLRLFDHDNSGTITIEEFCDTLGLVPKQEYMEKVQTNREKSEGGGIMDGVKIITEDPELSDSTKEEIVRIARQAQEQFVNERDIARHMKARLDDMFGRAWHVIVGRYQYGSFCTHETGSLFHFYVLRNAVLVWKTP 457
[Close]
BLAST of Dynein light chain vs. TrEMBL
Match: A0A1I8I7N8 (Dynein light chain OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig001380g1 PE=3 SV=1)

HSP 1 Score: 117.472 bits (293), Expect = 1.015e-29
Identity = 62/173 (35.84%), Postives = 100/173 (57.80%), Query Frame = 3 
Query:   45 MELLKIFNEIDVGRTGIITEEQLLDF-QERNGLNNFAEKWLNMFDVENEGKIRIENFASTVGLEP-EDYVDQTIQNHEESGQFIENVDIIKEDDNMPQNLKDAIINTSIDALNNYEKESQMAKHIKIFLDDNFGKVWHAVVGKSQFGSNISHLPESFMHYKIEDHAFLIFKTP 557
            M+ L  +  ID   +G IT E+L  + ++ N  + F EKWL +FD +N G I IE F  T+GL P ++Y+++   N E+S   ++ V II ED +M   LK+ I+  +  A   +E E  +A+++K  LD  F + WH +VG+ Q+GS  +H      H+ +  +A L++KTP
Sbjct:    1 MDFLTAYEAIDTDFSGEITSEELEAYCRKHNYEDKFVEKWLRLFDHDNSGTITIEEFCETLGLVPKQEYMEKVQINREKSSGVMDGVKIITEDPDMTDELKEEIVQLARTAQEQFENERDIARYMKSELDAKFDRAWHVIVGRFQYGSFCTHEVGRLFHFYVVRNAILVWKTP 173
[Close]
BLAST of Dynein light chain vs. TrEMBL
Match: A0A1I8IZM2 (Uncharacterized protein OS=Macrostomum lignano OX=282301 PE=4 SV=1)

HSP 1 Score: 115.161 bits (287), Expect = 5.075e-28
Identity = 63/170 (37.06%), Postives = 97/170 (57.06%), Query Frame = 3 
Query:   45 MELLKIFNEIDVGRTGIITEEQLLDFQER-NGLNNFAEKWLNMFDVENEGKIRIENFASTVGLEP-EDYVDQTIQNHEES--GQFIENVDIIKEDDNMPQNLKDAIINTSIDALNNYEKESQMAKHIKIFLDDNFGKVWHAVVGKSQFGSNISHLPESFMHYKIEDHAFL 542
            M+ L  F +ID   +G IT E+L  +  R N  + F EKWL +FD +N G I IE F  T+GL P ++Y+++   N E+S  G  ++ V II ED  +  + K+ I+  +  A   +  E  +A+H+K  LDD FG+ WH +VG+ Q+GS  +H   S  H+ +  +A L
Sbjct:    1 MDFLHAFEDIDSDFSGEITTEELEAYCRRHNYEDRFVEKWLRLFDHDNSGTITIEEFCDTLGLVPKQEYMEKVQTNREKSEGGGIMDGVKIITEDPELSDSTKEEIVRIARQAQEQFVNERDIARHMKARLDDMFGRAWHVIVGRYQYGSFCTHETGSLFHFYVLRNAVL 170
[Close]
BLAST of Dynein light chain vs. TrEMBL
Match: A0A267EQG8 (Uncharacterized protein OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig026868g1 PE=4 SV=1)

HSP 1 Score: 111.309 bits (277), Expect = 6.153e-27
Identity = 61/196 (31.12%), Postives = 105/196 (53.57%), Query Frame = 3 
Query:   48 ELLKIFNEIDVGRTGIITEEQLLDFQERNGLNN-FAEKWLNMFDVENEGKIRIENFASTVGLEP-EDYVDQ---------------------TIQNHEESGQF---IENVDIIKEDDNMPQNLKDAIINTSIDALNNYEKESQMAKHIKIFLDDNFGKVWHAVVGKSQFGSNISHLPESFMHYKIEDHAFLIFKTP 557
            + LK F  ID   +G IT+++L ++ ++   ++ F +KWL++FD +N G I +E +  T+GL P  DY+++                      +Q+    G+    ++NV I+  DD +P++L   I+  + +    Y  E  +AKHIK  LDD  G+ WHA+VG+ Q+GS  +H     +H  +   AFL+++TP
Sbjct:    3 DFLKAFEAIDTDFSGEITKQELEEYCKKQEFDDRFIQKWLDLFDADNSGTITVEEYCETLGLTPNTDYIEKVETRRVNAGPPGTGVDEADQYAVQSSGNDGEIDDSLDNVQILAVDDQLPEDLMRTIVRLAREGQAVYSLEKDIAKHIKAGLDDLDGRAWHAIVGRFQYGSFCTHEVGRMLHCFVGRFAFLVWRTP 198
[Close]
BLAST of Dynein light chain vs. Ensembl Cavefish
Match: ENSAMXT00000047143.1 (dynein light chain 2, cytoplasmic [Source:NCBI gene;Acc:103041528])

HSP 1 Score: 48.9062 bits (115), Expect = 7.499e-8
Identity = 24/84 (28.57%), Postives = 48/84 (57.14%), Query Frame = 3 
Query:  303 IIKEDDNMPQNLKDAIINTSIDALNNYEKESQMAKHIKIFLDDNFGKVWHAVVGKSQFGSNISHLPESFMHYKIEDHAFLIFKT 554
            +IK  D M ++++   ++ +  A+  Y  E  +A +IK   D  +   WH +VG++ FGS ++H  + F+++ +   A L+FK+
Sbjct:    7 VIKNAD-MSEDMQQDAVDCATQAMEKYNIEKDIAAYIKKEFDKKYNPTWHCIVGRN-FGSYVTHETKHFIYFYLGQVAILLFKS 88
[Close]
BLAST of Dynein light chain vs. Ensembl Cavefish
Match: dynll2b (dynein light chain 2, cytoplasmic [Source:NCBI gene;Acc:103041528])

HSP 1 Score: 48.9062 bits (115), Expect = 7.499e-8
Identity = 24/84 (28.57%), Postives = 48/84 (57.14%), Query Frame = 3 
Query:  303 IIKEDDNMPQNLKDAIINTSIDALNNYEKESQMAKHIKIFLDDNFGKVWHAVVGKSQFGSNISHLPESFMHYKIEDHAFLIFKT 554
            +IK  D M ++++   ++ +  A+  Y  E  +A +IK   D  +   WH +VG++ FGS ++H  + F+++ +   A L+FK+
Sbjct:    7 VIKNAD-MSEDMQQDAVDCATQAMEKYNIEKDIAAYIKKEFDKKYNPTWHCIVGRN-FGSYVTHETKHFIYFYLGQVAILLFKS 88
[Close]
BLAST of Dynein light chain vs. Ensembl Yeast
Match: DYN2 (Cytoplasmic light chain dynein, microtubule motor protein; required for intracellular transport and cell division; involved in mitotic spindle positioning; forms complex with dynein intermediate chain Pac11p that promotes Dyn1p homodimerization, potentiates motor processivity; Dyn2p-Pac11p complex important for interaction of dynein motor complex with dynactin complex; acts as molecular glue to dimerize, stabilize Nup82-Nsp1-Nup159 complex module of cytoplasmic pore filaments [Source:SGD;Acc:S000002832])

HSP 1 Score: 61.6178 bits (148), Expect = 2.398e-13
Identity = 34/88 (38.64%), Postives = 53/88 (60.23%), Query Frame = 3 
Query:  291 ENVDIIKEDDNMPQNLKDAIINTSIDALNNYEKESQMAKHIKIFLDDNFGKVWHAVVGKSQFGSNISHLPESFMHYKIEDHAFLIFKT 554
            ++  I+K  D +   LK+ I+  S DAL+ Y+ E  +A  +K  LD  +G  WH +VGK+ FGS ++H    F+++ I   AFL+FKT
Sbjct:    6 KSTPIVKASD-ITDKLKEDILTISKDALDKYQLERDIAGTVKKQLDVKYGNTWHVIVGKN-FGSYVTHEKGHFVYFYIGPLAFLVFKT 91
[Close]
BLAST of Dynein light chain vs. Ensembl Nematostella
Match: EDO44582 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RVI5])

HSP 1 Score: 47.3654 bits (111), Expect = 1.361e-7
Identity = 26/88 (29.55%), Postives = 47/88 (53.41%), Query Frame = 3 
Query:  291 ENVDIIKEDDNMPQNLKDAIINTSIDALNNYEKESQMAKHIKIFLDDNFGKVWHAVVGKSQFGSNISHLPESFMHYKIEDHAFLIFKT 554
            E   +IK  D M ++++   I  +  AL  +  E  +A  IK   D  +   WH +VG++ FGS ++H  + F+++ +   A L+FK+
Sbjct:    3 ERKAVIKNAD-MAEDMQTDAIECATQALEKFNIEKDIAAFIKKEFDKKYNPTWHCIVGRN-FGSYVTHETKHFIYFYLGQVAILLFKS 88
[Close]
BLAST of Dynein light chain vs. Ensembl Medaka
Match: dynll1 (dynein light chain 2, cytoplasmic [Source:NCBI gene;Acc:101171417])

HSP 1 Score: 49.2914 bits (116), Expect = 5.949e-8
Identity = 25/84 (29.76%), Postives = 47/84 (55.95%), Query Frame = 3 
Query:  303 IIKEDDNMPQNLKDAIINTSIDALNNYEKESQMAKHIKIFLDDNFGKVWHAVVGKSQFGSNISHLPESFMHYKIEDHAFLIFKT 554
            +IK  D M ++++   +  +  AL  Y  E  +A +IK   D  +   WH +VG++ FGS ++H  + F+++ +   A L+FK+
Sbjct:    7 VIKNAD-MSEDMQQDAVECATQALEKYNIEKDIAAYIKKEFDKKYNPTWHCIVGRN-FGSYVTHETKHFIYFYLGQVAILLFKS 88
[Close]
BLAST of Dynein light chain vs. Ensembl Medaka
Match: ENSORLT00000005747.2 (dynein light chain 2, cytoplasmic [Source:NCBI gene;Acc:101162462])

HSP 1 Score: 48.521 bits (114), Expect = 1.205e-7
Identity = 24/84 (28.57%), Postives = 47/84 (55.95%), Query Frame = 3 
Query:  303 IIKEDDNMPQNLKDAIINTSIDALNNYEKESQMAKHIKIFLDDNFGKVWHAVVGKSQFGSNISHLPESFMHYKIEDHAFLIFKT 554
            +IK  D M + ++   ++ +  A+  Y  E  +A +IK   D  +   WH +VG++ FGS ++H  + F+++ +   A L+FK+
Sbjct:    7 VIKNAD-MSEEMQQDAVDCATQAMEKYNIEKDIAAYIKKEFDKKYNPTWHCIVGRN-FGSYVTHETKHFIYFYLGQVAILLFKS 88
[Close]
BLAST of Dynein light chain vs. Ensembl Medaka
Match: DYNLL2 (dynein light chain 2, cytoplasmic [Source:NCBI gene;Acc:101174042])

HSP 1 Score: 47.3654 bits (111), Expect = 3.053e-7
Identity = 23/84 (27.38%), Postives = 47/84 (55.95%), Query Frame = 3 
Query:  303 IIKEDDNMPQNLKDAIINTSIDALNNYEKESQMAKHIKIFLDDNFGKVWHAVVGKSQFGSNISHLPESFMHYKIEDHAFLIFKT 554
            +IK  D M   ++   ++ ++ A+  Y  E  +A ++K   D  +   WH +VG++ FGS ++H  + F+++ +   A L+FK+
Sbjct:    7 VIKNAD-MSDEMQQDAVDCAMQAMEKYNIEKDIAAYVKKEFDKKYNPTWHCIVGRN-FGSYVTHETKHFIYFYLGQVAILLFKS 88
[Close]
BLAST of Dynein light chain vs. Planmine SMEST
Match: SMESG000081226.1 (SMESG000081226.1)

HSP 1 Score: 348.206 bits (892), Expect = 3.577e-124
Identity = 171/171 (100.00%), Postives = 171/171 (100.00%), Query Frame = 3 
Query:   45 MELLKIFNEIDVGRTGIITEEQLLDFQERNGLNNFAEKWLNMFDVENEGKIRIENFASTVGLEPEDYVDQTIQNHEESGQFIENVDIIKEDDNMPQNLKDAIINTSIDALNNYEKESQMAKHIKIFLDDNFGKVWHAVVGKSQFGSNISHLPESFMHYKIEDHAFLIFKTP 557
            MELLKIFNEIDVGRTGIITEEQLLDFQERNGLNNFAEKWLNMFDVENEGKIRIENFASTVGLEPEDYVDQTIQNHEESGQFIENVDIIKEDDNMPQNLKDAIINTSIDALNNYEKESQMAKHIKIFLDDNFGKVWHAVVGKSQFGSNISHLPESFMHYKIEDHAFLIFKTP
Sbjct:    1 MELLKIFNEIDVGRTGIITEEQLLDFQERNGLNNFAEKWLNMFDVENEGKIRIENFASTVGLEPEDYVDQTIQNHEESGQFIENVDIIKEDDNMPQNLKDAIINTSIDALNNYEKESQMAKHIKIFLDDNFGKVWHAVVGKSQFGSNISHLPESFMHYKIEDHAFLIFKTP 171
[Close]
BLAST of Dynein light chain vs. Planmine SMEST
Match: SMESG000081215.1 (SMESG000081215.1)

HSP 1 Score: 127.102 bits (318), Expect = 6.525e-38
Identity = 60/66 (90.91%), Postives = 62/66 (93.94%), Query Frame = 3 
Query:   51 LLKIFNEIDVGRTGIITEEQLLDFQERNGLNNFAEKWLNMFDVENEGKIRIENFASTVGLEPEDYV 248
            LLKIFNEIDVGRTGIITEEQLLDFQERNGL NFAEKWLN+FDVENEGKIRIE   ST+GLEPEDYV
Sbjct:   27 LLKIFNEIDVGRTGIITEEQLLDFQERNGLTNFAEKWLNLFDVENEGKIRIEYICSTIGLEPEDYV 92
[Close]
BLAST of Dynein light chain vs. Planmine SMEST
Match: SMESG000008592.1 (SMESG000008592.1)

HSP 1 Score: 125.946 bits (315), Expect = 2.017e-36
Identity = 70/187 (37.43%), Postives = 108/187 (57.75%), Query Frame = 3 
Query:   45 MELLKIFNEIDVGRTGIITEEQLLDFQ-ERNGLNNFAEKWLNMFDVENEGKIRIENFASTVGLEP-EDYVDQTIQNHEESGQFIE--------------NVDIIKEDDNMPQNLKDAIINTSIDALNNYEKESQMAKHIKIFLDDNFGKVWHAVVGKSQFGSNISHLPESFMHYKIEDHAFLIFKTP 557
            M+L+K F EID   +G IT+++L+++  +++    F  KW+ +FD  N G+I +E F   +GL+P EDY+ Q     EES   I+              +V+II+ED +     +   I+ S  A  +++ E  +AK IK  LD+ + K+WH VV +S FGS ISH    FMHYKIE+  +LI++TP
Sbjct:    1 MDLIKAFEEIDTDYSGEITKDELINYMIKKDYEMGFVNKWMEIFDPNNTGRITLEEFCDALGLQPNEDYLQQVQTKQEESKPMIQICPPFNEETNEEIIDVEIIREDPDTTAEFRQFAIDVSHQASKDHKLEKDIAKSIKKKLDEEYNKIWHVVVARSTFGSFISHKSGKFMHYKIENFCYLIWQTP 187
[Close]
BLAST of Dynein light chain vs. Planmine SMEST
Match: SMESG000042102.1 (SMESG000042102.1)

HSP 1 Score: 103.605 bits (257), Expect = 1.096e-27
Identity = 60/181 (33.15%), Postives = 94/181 (51.93%), Query Frame = 3 
Query:   45 MELLKIFNEIDVGRTGIITEEQLLDFQE-RNGLNNFAEKWLNMFDVENEGKIRIENFASTVGLEPEDYVDQTIQNHEESGQFIE---------NVDIIKEDDNMPQNLKDAIINTSIDALNNYEKESQMAKHIKIFLDDNFGKVWHAVVGKSQFGSNISHLPESFMHYKIEDHAFLIFKTP 557
            ME +K F EID   +G IT  +L+ +   +N    F EKWLN+FD +N G I +E F +T+GL P     + I+  +   + ++         ++ +I ED       KD  +    +A NN      +AK++K  LD  FG+ W+ VV    +GS +SH P +F+H K+   A L++K P
Sbjct:    1 MEFIKAFEEIDSDNSGEITRGELIRYMRLKNYKPAFVEKWLNIFDADNSGTITLEEFCNTLGLIPNKNYQKRIEKRKSEKELLKRKSLLIPLYDLYVIDEDPLNDPKFKDFCMKICQEATNNENDFISIAKYLKSVLDVKFGRSWNVVVDIDAYGSFLSHEPGAFIHIKVRKFAILLWKVP 181
[Close]
BLAST of Dynein light chain vs. Planmine SMEST
Match: SMESG000078154.1 (SMESG000078154.1)

HSP 1 Score: 93.2041 bits (230), Expect = 3.129e-22
Identity = 52/184 (28.26%), Postives = 95/184 (51.63%), Query Frame = 3 
Query:   36 ILPMELLKIFNEIDVGRTGIITEEQLLDFQERNGLN-NFAEKWLNMFDVENEGKIRIENFASTVGLEPEDYVDQTIQNHEESGQFI---------ENVDIIKEDDNMPQNLKDAIINTSIDALNNYEKESQMAKHIKIFLDDNFGKVWHAVVGKSQFGSNISHLPESFMHYKIEDHAFLIFKTP 557
            ++ ++ LK F EID   +G I+ E++  +  R+     F +KWL +F+   +G+I IE++  ++GL P ++    +  + + G  I          NV II+ +  M   +K  II  +  A      E ++A+ IK  LD  +G +W  +V +  +   +SH   S +H+ + +H+F I+KTP
Sbjct:  239 VMSLDFLKTFEEIDGDFSGEISYEEISTYMRRHNFEAEFVDKWLTLFEPNKDGRITIESYCGSLGLIPREHYYGRVVANRKVGSLIPRGNATEDWANVRIIRLEPLMDDTMKTFIIRLARKAQKELATEYEIARFIKQSLDLRWGGLWQVIVSRYPYACYLSHEMASLIHFWLLEHSFCIWKTP 422
The following BLAST results are available for this feature:
BLAST of Dynein light chain vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5
Match NameE-valueIdentityDescription
DYNLL14.643e-830.95dynein light chain LC8-type 1 [Source:HGNC Symbol;... [more]
DYNLL14.643e-830.95dynein light chain LC8-type 1 [Source:HGNC Symbol;... [more]
DYNLL14.643e-830.95dynein light chain LC8-type 1 [Source:HGNC Symbol;... [more]
DYNLL14.643e-830.95dynein light chain LC8-type 1 [Source:HGNC Symbol;... [more]
DYNLL14.643e-830.95dynein light chain LC8-type 1 [Source:HGNC Symbol;... [more]
back to top
BLAST of Dynein light chain vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 5
Match NameE-valueIdentityDescription
dlc-56.020e-1232.05Dynein Light Chain [Source:UniProtKB/TrEMBL;Acc:Q... [more]
dlc-14.412e-830.95Dynein light chain 1, cytoplasmic [Source:UniProt... [more]
dlc-14.412e-830.95Dynein light chain 1, cytoplasmic [Source:UniProt... [more]
dlc-14.412e-830.95Dynein light chain 1, cytoplasmic [Source:UniProt... [more]
dlc-29.635e-629.55Probable dynein light chain 2, cytoplasmic [Sourc... [more]
back to top
BLAST of Dynein light chain vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5
Match NameE-valueIdentityDescription
ctp5.054e-829.76gene:FBgn0011760 transcript:FBtr0070706[more]
ctp5.054e-829.76gene:FBgn0011760 transcript:FBtr0070704[more]
ctp5.054e-829.76gene:FBgn0011760 transcript:FBtr0307065[more]
ctp5.054e-829.76gene:FBgn0011760 transcript:FBtr0070707[more]
Cdlc21.796e-729.76gene:FBgn0026141 transcript:FBtr0077924[more]
back to top
BLAST of Dynein light chain vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
dynll2a8.849e-828.57dynein, light chain, LC8-type 2a [Source:ZFIN;Acc:... [more]
dynll2b8.849e-828.57dynein, light chain, LC8-type 2b [Source:ZFIN;Acc:... [more]
dynll2a8.849e-828.57dynein, light chain, LC8-type 2a [Source:ZFIN;Acc:... [more]
dynll11.075e-729.76dynein, light chain, LC8-type 1 [Source:ZFIN;Acc:Z... [more]
dynll11.075e-729.76dynein, light chain, LC8-type 1 [Source:ZFIN;Acc:Z... [more]
back to top
BLAST of Dynein light chain vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 2
Match NameE-valueIdentityDescription
dynll21.355e-728.57dynein light chain LC8-type 2 [Source:NCBI gene;Ac... [more]
dynll19.137e-728.41dynein light chain LC8-type 1 [Source:NCBI gene;Ac... [more]
back to top
BLAST of Dynein light chain vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5
Match NameE-valueIdentityDescription
BC0485071.083e-830.95cDNA sequence BC048507 [Source:MGI Symbol;Acc:MGI:... [more]
Dynll13.188e-830.95dynein light chain LC8-type 1 [Source:MGI Symbol;A... [more]
Dynll13.188e-830.95dynein light chain LC8-type 1 [Source:MGI Symbol;A... [more]
Dynll21.026e-728.57dynein light chain LC8-type 2 [Source:MGI Symbol;A... [more]
Dynll21.026e-728.57dynein light chain LC8-type 2 [Source:MGI Symbol;A... [more]
back to top
BLAST of Dynein light chain vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|Q6BZF8|DYL1_DEBHA6.660e-1238.64Dynein light chain 1, cytoplasmic OS=Debaryomyces ... [more]
sp|Q02647|DYL1_YEAST1.665e-1138.64Dynein light chain 1, cytoplasmic OS=Saccharomyces... [more]
sp|Q759T0|DYL1_ASHGO2.771e-1138.10Dynein light chain 1, cytoplasmic OS=Ashbya gossyp... [more]
sp|Q94748|DYL2_SCHMA3.394e-1134.09Probable dynein light chain OS=Schistosoma mansoni... [more]
sp|Q6CWX4|DYL1_KLULA1.158e-1039.29Dynein light chain 1, cytoplasmic OS=Kluyveromyces... [more]
back to top
BLAST of Dynein light chain vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
A0A267EIW97.011e-3237.71Dynein light chain OS=Macrostomum lignano OX=28230... [more]
A0A1I8IZR38.506e-3037.29Uncharacterized protein OS=Macrostomum lignano OX=... [more]
A0A1I8I7N81.015e-2935.84Dynein light chain OS=Macrostomum lignano OX=28230... [more]
A0A1I8IZM25.075e-2837.06Uncharacterized protein OS=Macrostomum lignano OX=... [more]
A0A267EQG86.153e-2731.12Uncharacterized protein OS=Macrostomum lignano OX=... [more]
back to top
BLAST of Dynein light chain vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 2
Match NameE-valueIdentityDescription
ENSAMXT00000047143.17.499e-828.57dynein light chain 2, cytoplasmic [Source:NCBI gen... [more]
dynll2b7.499e-828.57dynein light chain 2, cytoplasmic [Source:NCBI gen... [more]
back to top
BLAST of Dynein light chain vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 0
Match NameE-valueIdentityDescription
back to top
BLAST of Dynein light chain vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 1
Match NameE-valueIdentityDescription
DYN22.398e-1338.64Cytoplasmic light chain dynein, microtubule motor ... [more]
back to top
BLAST of Dynein light chain vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 1
Match NameE-valueIdentityDescription
EDO445821.361e-729.55Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
back to top
BLAST of Dynein light chain vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 3
Match NameE-valueIdentityDescription
dynll15.949e-829.76dynein light chain 2, cytoplasmic [Source:NCBI gen... [more]
ENSORLT00000005747.21.205e-728.57dynein light chain 2, cytoplasmic [Source:NCBI gen... [more]
DYNLL23.053e-727.38dynein light chain 2, cytoplasmic [Source:NCBI gen... [more]
back to top
BLAST of Dynein light chain vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5
Match NameE-valueIdentityDescription
SMESG000081226.13.577e-124100.00SMESG000081226.1[more]
SMESG000081215.16.525e-3890.91SMESG000081215.1[more]
SMESG000008592.12.017e-3637.43SMESG000008592.1[more]
SMESG000042102.11.096e-2733.15SMESG000042102.1[more]
SMESG000078154.13.129e-2228.26SMESG000078154.1[more]
back to top
Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30013082 ID=SMED30013082|Name=Dynein light chain|organism=Schmidtea mediterranea sexual|type=transcript|length=606bp
AACTTTTAGATATTTTTAAATTCATTCTTGTTTGAATATTACCAATGGAG
CTTTTGAAAATATTCAATGAAATCGATGTTGGCAGAACAGGAATAATCAC
AGAAGAGCAATTGTTGGATTTTCAGGAAAGGAACGGATTAAACAATTTTG
CAGAAAAATGGCTAAACATGTTTGATGTGGAAAATGAAGGTAAAATACGA
ATTGAAAACTTTGCTAGTACAGTCGGTTTGGAACCAGAAGACTACGTTGA
TCAGACTATACAGAACCACGAGGAATCAGGCCAGTTCATTGAAAATGTTG
ATATAATAAAGGAAGATGACAATATGCCACAAAATTTGAAAGACGCAATT
ATCAACACTAGCATTGATGCGCTTAATAATTATGAAAAAGAATCACAAAT
GGCAAAGCATATAAAGATCTTCCTCGATGATAATTTTGGTAAAGTTTGGC
ACGCTGTTGTCGGAAAATCACAATTTGGAAGTAATATTAGCCATCTGCCA
GAAAGTTTTATGCACTACAAAATCGAAGATCACGCGTTTTTAATTTTCAA
AACTCCAAACCTACAAAATGACGATTAAAATTATTATAATTTACAAAATT
AACTCT
back to top

protein sequence of SMED30013082-orf-1

>SMED30013082-orf-1 ID=SMED30013082-orf-1|Name=SMED30013082-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=178bp
MELLKIFNEIDVGRTGIITEEQLLDFQERNGLNNFAEKWLNMFDVENEGK
IRIENFASTVGLEPEDYVDQTIQNHEESGQFIENVDIIKEDDNMPQNLKD
AIINTSIDALNNYEKESQMAKHIKIFLDDNFGKVWHAVVGKSQFGSNISH
LPESFMHYKIEDHAFLIFKTPNLQNDD*
back to top
Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: molecular function
TermDefinition
GO:0005509calcium ion binding
GO:0003774motor activity
GO:0008574ATP-dependent microtubule motor activity, plus-end-directed
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000016pharynx
PLANA:0000018Category 4 cell
PLANA:0000034epidermis
PLANA:0000418head
PLANA:0002032epidermal cell
Vocabulary: INTERPRO
TermDefinition
IPR037177DLC_sf
IPR002048EF_hand_dom
IPR001372Dynein_light_chain_typ-1/2
IPR011992EF-hand-dom_pair
Vocabulary: biological process
TermDefinition
GO:0007017microtubule-based process
GO:0006810transport
GO:0030473nuclear migration along microtubule
GO:0040001establishment of mitotic spindle localization
GO:0051292nuclear pore complex assembly
GO:2000582positive regulation of ATP-dependent microtubule motor activity, plus-end-directed
Vocabulary: cellular component
TermDefinition
GO:0030286dynein complex
GO:0005643nuclear pore
GO:0005737cytoplasm
GO:0005777peroxisome
GO:0005856cytoskeleton
GO:0005868cytoplasmic dynein complex
GO:0005874microtubule
GO:0005875microtubule associated complex
GO:0005881cytoplasmic microtubule
GO:1990429peroxisomal importomer complex
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR001372Dynein light chain, type 1/2SMARTSM01375Dynein_light_2coord: 82..170
e-value: 1.9E-18
score: 77.3
IPR001372Dynein light chain, type 1/2PFAMPF01221Dynein_lightcoord: 92..170
e-value: 1.9E-20
score: 73.0
IPR001372Dynein light chain, type 1/2PANTHERPTHR11886DYNEIN LIGHT CHAINcoord: 80..170
IPR037177Dynein light chain superfamilyGENE3DG3DSA:3.30.740.10coord: 87..170
e-value: 8.5E-20
score: 72.7
IPR037177Dynein light chain superfamilySUPERFAMILYSSF54648DLCcoord: 86..171
NoneNo IPR availableGENE3DG3DSA:1.10.238.10coord: 1..86
e-value: 9.6E-7
score: 30.3
NoneNo IPR availablePANTHERPTHR11886:SF35DYNEIN LIGHT CHAIN 2, CYTOPLASMICcoord: 80..170
IPR002048EF-hand domainPROSITEPS50222EF_HAND_2coord: 1..33
score: 8.906
IPR002048EF-hand domainPROSITEPS50222EF_HAND_2coord: 36..66
score: 5.308
IPR011992EF-hand domain pairSUPERFAMILYSSF47473EF-handcoord: 2..61